Miracle-dz/UniFAR-FTUs huggingface dataset:
Design, consumption and marketing: outcomes, process, philosophy and future directions

Whether we know it or not (the best design is the least obvious), design plays a role in many of the decisions and experiences we as consumers and marketers take for granted. For better or worse, every customer experience is the result of a design decision and execution, while customers are also curators of their identities, usually with the help of designer brands, designer goods, designed servicescapes, experiences and co-designed social media platforms. These observations, along with the belief that more rather than less interaction between design, consumption and marketing research is needed, motivated this special issue. Although design has always played a role in the broad church we call marketing, scholarly interest between the two disciplines remained relatively rare (outside of marketing communications) and typically involved little appreciation for the practices, processes and philosophies of each. Measures of the effectiveness of design cues on a range of marketing-related outcomes such as likeability, attractiveness, willingness to buy (Fajardo, Zhang, & Tsiros, 2016) and perceptions of quality reflected standard research interests in marketing, while, apart from concern regarding the effects of consumerism, product form, servicescape, logo and identity work were as far as designers went in their embrace of marketing and the consumer. This special issue aimed to build on more recent interest in what can best be called the design–marketing interface. With alternate framings of the consumer (Belk, Sherry, & Wallendorf 1989; Hirschman & Holbrook 1982), interest has moved to the motives at the heart of identity design decisions (Arnould & Thompson, 2005), leveraging the techniques of designers for better marketing decisions (Cayla & Arnould, 2013), triggering emotions and the senses (Baron, Harris, & Harris, 2001; Kozinets et al., 2002; Pine & Gilmore, 1999), building more relevant cultural brands (Allen, Fournier, & Miller 2008; Holt & Cameron, 2010) or enabling brand relevance at the strategic level (Beverland, Micheli, & Wilner, 2015), offering alternate views on product innovation (Verganti, 2009) and complementary logics to market orientation (Beverland & Farrelly, 2007; Venkatesh, Digerfeldt-Mansson, Brunel, & Chen, 2012), improving the product development management process (Beverland, Micheli, & Farrelly, 2016; Micheli, Jaina, Goffin, Lemke, & Verganti, 2012) and reinvigorating interest in design tools such as anthropomorphism (Brown & Ponsonby-McCabe, 2013). In so doing, we build on previous special issues dedicated to further crossover between design, marketing and consumption published in this journal (Journal of Marketing Management, 2007, Vol. 23 Iss. 9–10) and the Journal of Product Innovation Management (2005 and 2012). Before turning our attention to the articles and commentaries in this issue, we will briefly review the ways in which design and marketing have intersected over the years, JOURNAL OF MARKETING MANAGEMENT, 2017 VOL. 33, NOS. 3–4, 159–172 http://dx.doi. org/10.1080/0267257X.2017. 1283908
Algorithm for Disease Association Studies Using Functionally Informative Haplotype Motif

Selecting a subset of genetic polymorphism data is considered to be an essential step for locating disease related genes. Haplotypes, contiguous sets of correlated single nucleotide polymorphisms (SNPs), may provide a promising way out for analyzing linkage data involved. At present, some flexible block- free "haplotype motif models are demonstrated to deduce conserved structure within haplotype. However, while those haplotype motifs may characterize true haplotype conservation patterns of a target genomic region, they do not necessarily contain functional significant SNPs directly associated with disease. In this paper, we address this challenge by redefining the mathematical model of haplotype motif. We present an integrative haplotype motif selection system which can simultaneously deduce motif not only statistically significant but also highly correlated to deleterious variation. To evaluate our system, we compared our new model with some existing models on finding informative haplotype motifs on real data set to show its advantages in disease association studies.
Decision tree design using a probabilistic model

A sequential optical character recognition algorithm, ideally suited for implementation by means of microprocessors with limited storage capabilities, is formulated in terms of a binary decision tree. Upper bounds On the recognition performance are derived in terms of the stability of the digitized picture elements. The design process is described in detail. The algorithm is tested on single-font typewritten characters and the experimental and theoretical results are compared.
Information and Optimal Trading Strategies with Dark Pools

We study how asymmetric information affects market participants’ choice of trading venue (either an exchange or dark pool), and the optimal submission strategies in a sequential trading game. The exchange is organized as a fully transparent limit order book, and the dark pool is an opaque venue where orders are continuously executed at the midpoint of the bid and ask prices that prevail in the exchange. We find that when the limit order book conveys no information rational uninformed traders never trade in the dark pool due to price risk. However, price risk may be reduced when the information in the book induces an uninformed buyer (seller) to believe that the value of the asset is high (low) since the order was previously submitted by an informed buyer (seller). The optimal strategy of an informed trader takes into account the information leakage, and the strategic response of each type of trader in the subsequent stages. Our main finding is that, adding a dark pool alongside an exchange, may divert the informed trader from the exchange to the dark pool. When the execution risk in the dark pool is low, the informed trader decides to trade in the dark pool. In this case the adverse selection problem in the exchange reduces and consequently, the uninformed trader decides to switch from no trade to placing a limit order in the exchange.
Dietary overlap of invertivorous fishes and macroinvertebrates in the Gila River, New Mexico

Abstract The diets of stoneflies (Perlodidae) and hellgrammites (Corydalidae) from the Gila River, New Mexico, were quantified and compared to diets of three native fishes that also occupy riffle habitats along with stoneflies and hellgrammites: speckled dace (Rhinichthys osculus); longfin dace (Agosia chrysogaster); desert sucker (Catostomus clarkii). The highest overlap occurred among corydalids, desert sucker, and longfin dace, which had diets dominated by amorphous detritus. Speckled dace and perlodids consumed less amorphous detritus, with nymphs of mayflies and larval black flies dominating their respective diets. Our results suggest moderate to high overlap of resources among invertivorous fishes and invertebrates. Although we found high dietary overlap between corydalids and two fishes, it is unclear whether amorphous detritus is a limiting resource that drives competitive interactions.
Sources of Return and Volatility Spillover for Pakistan: An Analysis of Exogenous Factors by using EGARCH Model

The purpose of this research is to determine the behavior and magnitude of return movements and volatility movements of KSE-100 index (Pakistan) with respective global index FPI (Foreign portfolio Investment), FDI (Foreign direct Investment). The ultimate goal is to find out the diversification opportunity of FPI for international investors during the Global financial crisis as well as to understand the behavior of investors during crisis. We found that FPI and FDI strong predictors of KSE-100 index. The results demonstrated that the negative behavior of return movements of KSE-100 with global index during crisis period provides an opportunity for international investors diversification.
Temperature-suitability maps for schistosomiasis in South Africa

Abstract The results of parasitological surveys have shown that both urinary and intestinal schistosomiasis occur widely among the human residents of South Africa. The national data on both diseases have now been incorporated into a geographical information system, to develop new maps based on defined temperature constraints. The disease data, obtained from a 'hard-copy' atlas of schistosomiasis, were used as a template to select temperature regimes that were (1) suitable and (2) unsuitable for the transmission of schistosomes to humans in South Africa. The regimes were derived from the published results of investigations in which the biology of larval schistosomes (i.e. schistosome transmission) was related to temperature in South Africa. Those regimes that were based on the estimated temperature minima for transmission corresponded more closely to the disease-distribution data than those based on the corresponding maxima. An estimate of the number of children living in the climate-suitable areas was made but, within the context of the spatial methodology used and the limitations of the available disease data, it was not possible to predict the prevalences of schistosomiasis.
Solution structure of apo CopZ from Bacillus subtilis: further analysis of the changes associated with the presence of copper.

The solution structure of apo CopZ from Bacillus subtilis has been determined with the aim of investigating the changes in the hydrophobic interactions around the M-X-C-X-X-C copper(I) binding motif upon metal binding. The methionine of this motif (Met 11 in CopZ) points toward the solvent in apo CopZ, whereas its sulfur atom is close to the metal ion in the metal-loaded protein, though probably not at binding distance. This change is associated with the weakening of the interaction between Leu 37 and Cys 16, present in the apo form, and the formation of an interaction between Met 11 and Tyr 65. Loops 1, 3, and 5 are affected by metal binding. Comparison with the structure of other homologous proteins confirms that often metal binding affects a hydrophobic patch around the metal site, possibly for optimizing and tuning the hydrophobic interactions with the partners. It is also shown that copper(I) exchanges among apo CopZ molecules in slow exchange on the NMR time scale, whereas it is known that such exchange between partner molecules (i.e., metallochaperones and metal pumps) is fast.
Diagnosis of the market for ideas and the role of industrial associations as intermediaries in the Brazilian context

Markets for technologies and ideas depend on the flow of knowledge and technology from one company to another or from universities and research institutes to industry. These markets are driven by the process known as open innovation. In recent years, the literature has emphasized the need to analyse the market for ideas through its constituent parts. The concept of technology and knowledge intermediaries is relatively new and has not yet been well defined. This article focuses on specific types of intermediaries in an attempt to enrich the conceptual framework of this knowledge domain and to identify the influences of variables at various contextual levels. The article focuses on the role of industrial associations as intermediaries connecting companies with other innovation system agents. By assessing the content of their respective websites, the authors compare the approaches of selected industrial associations in Brazil with counterparts in other countries. In doing so, they find differences between the two groups in mindset and attitudes to university–industry interaction. On the basis of their analysis, they diagnose shortcomings in the Brazilian context that need to be addressed if the country is to be competitive at the global level in terms of innovation and the effective exploitation of research.
The Effect of Aligning Business Strategy and Human Resource Management Practices on Organizational Outcomes

This research explores the relationship between business strategy, human resource management (HRM) practices, and organizational outcomes through two studies. The first study provides a practitioner’s perspective into the relationship between the business strategy and HRM practices and the challenges and opportunities managers face when aligning the two. The practitioner’s perspective was captured through short interviews with human resource (HR) managers and other business leaders. This portion of the research shows common patterns that help HR leaders in alignment, such as fostering good relationships with key business leaders, having an understanding of the business, and taking part in strategic planning. The second study tests the contingency theory of strategic human resource management to understand if the relationship between HRM practices and organizational outcomes is contingent on business strategy. Data were collected through an online questionnaire completed by call center general managers in China. The results indicate that price leadership strategy has a significant moderating effect on the relationship between job discretion and employee turnover.
Genome-Wide Analysis of Secondary Metabolite Gene Clusters in Ophiostoma ulmi and Ophiostoma novo-ulmi Reveals a Fujikurin-Like Gene Cluster with a Putative Role in Infection

The emergence of new microbial pathogens can result in destructive outbreaks, since their hosts have limited resistance and pathogens may be excessively aggressive. Described as the major ecological incident of the twentieth century, Dutch elm disease, caused by ascomycete fungi from the Ophiostoma genus, has caused a significant decline in elm tree populations (Ulmus sp.) in North America and Europe. Genome sequencing of the two main causative agents of Dutch elm disease (Ophiostoma ulmi and Ophiostoma novo-ulmi), along with closely related species with different lifestyles, allows for unique comparisons to be made to identify how pathogens and virulence determinants have emerged. Among several established virulence determinants, secondary metabolites (SMs) have been suggested to play significant roles during phytopathogen infection. Interestingly, the secondary metabolism of Dutch elm pathogens remains almost unexplored, and little is known about how SM biosynthetic genes are organized in these species. To better understand the metabolic potential of O. ulmi and O. novo-ulmi, we performed a deep survey and description of SM biosynthetic gene clusters (BGCs) in these species and assessed their conservation among eight species from the Ophiostomataceae family. Among 19 identified BGCs, a fujikurin-like gene cluster (OpPKS8) was unique to Dutch elm pathogens. Phylogenetic analysis revealed that orthologs for this gene cluster are widespread among phytopathogens and plant-associated fungi, suggesting that OpPKS8 may have been horizontally acquired by the Ophiostoma genus. Moreover, the detailed identification of several BGCs paves the way for future in-depth research and supports the potential impact of secondary metabolism on Ophiostoma genus’ lifestyle.
Local and Systemic Neutralizing Antibody Responses Induced by Intranasal Immunization with the Nontoxic Binding Domain of Toxin A from Clostridium difficile

ABSTRACT Fourteen of the 38 C-terminal repeats from Clostridium difficile toxin A (14CDTA) were cloned and expressed either with an N-terminal polyhistidine tag (14CDTA-HIS) or fused to the nontoxic binding domain from tetanus toxin (14CDTA-TETC). The recombinant proteins were successfully purified by bovine thyroglobulin affinity chromatography. Both C. difficile toxin A fusion proteins bound to known toxin A ligands present on the surface of rabbit erythrocytes. Intranasal immunization of BALB/c mice with three separate 10-μg doses of 14CDTA-HIS or -TETC generated significant levels of anti-toxin A serum antibodies compared to control animals. The coadministration of the mucosal adjuvant heat labile toxin (LT) from Escherichia coli (1 μg) significantly increased the anti-toxin A response in the serum and at the mucosal surface. Importantly, the local and systemic antibodies generated neutralized toxin A cytotoxicity. Impressive systemic and mucosal anti-toxin A responses were also seen following coadministration of 14CDTA-TETC with LTR72, an LT derivative with reduced toxicity which shows potential as a mucosal adjuvant for humans.
The Evaluation of User Mobility Behavior in Personal Communication Service Network

Cellular technology has shown a tremendous impact to communication behavior and human life. The growth of cellular users' increase every year world wide. GSM as the second generation still exist as the famous technology and soon the third generation comes as a competitor. This technology has delivered an opportunity to communicate to anyone, anywhere and anytime wherever the service is available. In terms of services, many network operators have expanded the service coverage to cope with the increased of user density in a certain service area and improved services to enhance quality of service. In this paper, three control mobility schemes of user movement using a certain threshold level are proposed to investigate user mobility behavior. Each of these schemes incorporates equal cell size and examines in similar mobile environment based random mobility model. Every user can move in any direction with equal probability. Based on hexagonal cell model, 49 cells have been developed as a service area for simulation environment. Two mobility characteristics: user distribution and direction are considered as parameters to analyze user behavior in the certain service area. Simulation results using three mobility control schemes: scheme A, scheme B and scheme C; have shown that in time domain analysis. Result shows that the direction of each MS for any implemented scheme is unique. In term of mobility characteristic, we find that 90% of service area are occupied by MS for both balanced and un-balanced strategies while in cell strategy approach the distribution for all the schemes the result is less that the above strategies in terms of service.
A flash-aware buffering scheme with the on-the-fly redo for efficient data management in flash storage

Thanks to remarkably fast random reads and rapidly decreasing prices per bit, flash storage has been regarded as a promising alternative to traditional hard disk drives (HDDs). Although flash storage has many distinguished hardware features, it still suffers from the poor I/O performance in the case of update operations. Due to the absence of in-place updates, differently from HDDs, flash storage needs to modify data through out-of-place updates. For this reason, it is required to continuously renew the mapping information between a logical page address and its new physical address, invalidating its old physical address. When the invalidated pages swallow most of free space in flash storage, the actions of garbage reclamation are needed. Since the actions of garbage reclamation are very costly, it is crucial to reduce the number of update operations for the use of flash storage in enterprise-scale database systems. In this light, we propose a new buffering scheme that evicts dirty pages without writing them to storage, thereby reducing the amount of update operations considerably. That is, our buffering scheme enables the flushing-less evictions of dirty pages. To correctly read a page undergoing its flushing-less eviction, we propose a new on-the-fly redo mechanism that enables restoring the lost updates of the page in normal database processing. For fast execution of the on-the-fly redo, we maintain memoryresident log data of a reasonable size. To show the performance advantages of the proposed scheme, we performed extensive experiments based on the TPC-C benchmark, by running them on the open-sourced Berkeley DB equipped with/without our scheme. The results show that our scheme yields a much better performance by reducing the amount of page updates significantly.
Three-dimensional measurements of non-diffusive fast ion transport in TORPEX

In the basic plasma physics device TORPEX, progress in the fundamental understanding of supra-thermal ion transport is achieved by extensive sets of three-dimensional (3D) data, together with numerical simulations of supra-thermal ion tracers in fluid turbulent fields. A miniaturized lithium 6+ ion source injects fast ions with energies up to 1 KeV and a double-gridded energy analyzer is used as a detector. The source is mounted on a toroidally movable system and the detector can be moved in the poloidal cross-section, allowing one to reconstruct 3D fast ion current profiles. Synchronous detection is used to enhance the signal-to-noise ratio. A modulated biasing voltage is applied to the fast ion source and an analog lock-in amplifier is used to demodulate the detector signal. The analog lock-in amplifier is specially designed to remove the capacitive noise associated with the voltage modulation. Radial transport of the fast ions, associated with plasma turbulence, is characterized. A synthetic diagnostic allows comparing the experimental results with numerical simulations of the fast ion transport in a global fluid simulation of the TORPEX plasma. A good agreement is shown.
Sub‐populations within the major European and African derived haplogroups R1b3 and E3a are differentiated by previously phylogenetically undefined Y‐SNPs

Single nucleotide polymorphisms on the Y chromosome (Y‐SNPs) have been widely used in the study of human migration patterns and evolution. Potential forensic applications of Y‐SNPs include their use in predicting the ethnogeographic origin of the donor of a crime scene sample, or exclusion of suspects of sexual assaults (the evidence of which often comprises male/female mixtures and may involve multiple perpetrators), paternity testing, and identification of non‐ and half‐siblings. In this study, we used a population of 118 African‐ and 125 European‐Americans to evaluate 12 previously phylogenetically undefined Y‐SNPs for their ability to further differentiate individuals who belong to the major African (E3a)‐ and European (R1b3, I)‐derived haplogroups. Ten of these markers define seven new sub‐clades (equivalent to E3a7a, E3a8, E3a8a, E3a8a1, R1b3h, R1b3i, and R1b3i1 using the Y Chromosome Consortium nomenclature) within haplogroups E and R. Interestingly, during the course of this study we evaluated M222, a sub‐R1b3 marker rarely used, and found that this sub‐haplogroup in effect defines the Y‐STR Irish Modal Haplotype (IMH). The new bi‐allelic markers described here are expected to find application in human evolutionary studies and forensic genetics. © 2006 Wiley‐Liss, Inc.
Anti Cariogenic Efficacy of Herbal and Conventional Tooth Pastes-A Comparative In-Vitro Study

1Assistant Professor, Oral Pathology and Microbiology, Department of Oral Pathology and Microbiology, College of Dental Sciences, Davangere, Karnataka, India; 2Reader, Oral Pathology and Microbiology, Department of Oral Pathology and Microbiology, College of Dental Sciences, Davangere, Karnataka, India; 3Professor in Oral Pathology and Microbiology, Department of Oral Pathology and Microbiology, College of Dental Sciences, Davangere, Karnataka, India.
Conservation law for multiple four-wave-mixing processes in a nonlinear optical medium.

When two optical waves at frequencies ${\mathrm{\ensuremath{\omega}}}_{1}$ and ${\mathrm{\ensuremath{\omega}}}_{2}$ interact in a medium with cubic nonlinearity, multiple four-wave-mixing processes can generate pairs of sidebands. A conservation law that connects the amplitudes of the pump waves and sidebands is shown to arise from the Manley-Rowe relations and from the infinite set of conservation relations of the nonlinear Schr\"odinger equation. The conservation relation is examined theoretically and verified experimentally for a variety of input pump power levels and asymmetries. It can be used as a diagnostic measure to determine if nonlinearities of higher order than cubic are present.