Miracle-dz/UniFAR-FTUs huggingface dataset:
Using Choice Experiments to Understand Visitors Preferences for the Man-Made Lake Ecotourism Services in Terengganu, Malaysia

This paper aims to capture the level of satisfaction of the visitors towards the ecotourism service attributes at Kenyir Lake, by providing results of a valuation study on the boat house services, which is the main focus in this research. A choice experiment is employed to estimate the visitors’ preferences for boat house service attributes. The attributes investigated were visitors guide (TG), provision of safety equipment (SAFE), coverage for communication system (COMM), package of activities (ACTV) and extra package price (EPP). The simple conditional logit (CL) model and CL interaction model were estimated in order to identify the preferences of the visitors from various service options of boat house attributes. This study presents implications for the policy makers in guiding the future management and the improvement of boat house services. The results of this study will be able to facilitate the future management in establishing an efficient implementation in order to improve the boat house services to fulfill the visitors’ satisfaction.
RNA-binding Proteins That Specifically Recognize the Selenocysteine Insertion Sequence of Human Cellular Glutathione Peroxidase mRNA (*)

Translational incorporation of the unusual amino acid selenocysteine in eukaryotes requires a coding region UGA codon (which otherwise serves as a termination signal), a selenocysteine insertion sequence (SECIS) in the 3′-untranslated region of the mRNA, and selenocysteyl-tRNA. The mechanisms involved in SECIS recognition by the eukaryotic translational machinery remain unknown. We report the detection of RNA-binding proteins that specifically recognize the SECIS from human cellular glutathione peroxidase (GPX1) transcripts. RNA gel shift assays showed three retarded bands after incubation with COS-1 whole cell lysate or S-100 cytosol fraction or with extracts from hepatoma cell lines HepG2 and Hep3B. The specificity of the binding was demonstrated by competition by cold unlabeled SECIS RNA and by lack of competition by other RNA species with similar stem-loop secondary structures, such as the human immunodeficiency virus (HIV) trans-activation-response region of HIV mRNA element, and mutated SECIS constructs. UV cross-linking and SDS-polyacrylamide gel electrophoresis revealed at least two proteins, with estimated molecular masses of 55,000 and 65,000 Da, that bind to the SECIS. Examination of a series of insertion and deletion SECIS mutants indicated recognition of the SECIS primarily through the basal stem region, although the upper stem, loop, and two of three short conserved sequences also appear to contribute to the affinity of the binding.
The effect of relational governance on business partnership performance: a Nedap AVI case

The aim of this research is to assess the effect of relational governance on business partnership performance. A conceptual model with three associated hypotheses is developed and tested. Business development managers of Nedap AVI (interviews), a technology company from the Netherlands and their global network of business partners (survey, N=41) provided data for the empirical analysis. The results show that establishing and building trust & commitment are of major importance in order to develop effective and successful business relationships with business partners. Relational governance, a construct existing of the dimensions; joint planning; joint problem solving; trust & commitment has a significant positive effect on one of the two performance indicators used in this study, perceived satisfaction (hypothesis 1). There is no evidence being found regarding a positive effect of relational governance on the other performance indicator that is adopted, sales growth rate (hypothesis 2). This research also investigated whether there is a mediating effect of perceived satisfaction on the sales growth rate. This assumption (hypothesis 3) cannot be confirmed based on the results of this study.
Domain‐related differentiation of working memory in the Japanese macaque (Macaca fuscata) frontal cortex: a positron emission tomography study

The lateral prefrontal cortex (LPFC) is important for working memory (WM) task performance. Neuropsychological and neurophysiological studies in monkeys suggest that the lateral prefrontal cortex is functionally segregated based on the working memory domain (spatial vs. non‐spatial). However, this is not supported by most human neuroimaging studies, and the discrepancy might be due to differences in methods and/or species (monkey neuropsychology/physiology vs. human neuroimaging). We used positron emission topography to examine the functional segregation of the lateral prefrontal cortex of Japanese macaques (Macaca fuscata) that showed near 100% accuracy on spatial and non‐spatial working memory tasks. Compared with activity during the non‐working memory control tasks, the dorsolateral prefrontal cortex (DLPFC) was more active during the non‐spatial, but not during the spatial, working memory task, although a muscimol microinjection into the dorsolateral prefrontal cortex significantly impaired the performance of both working memory tasks. A direct comparison of the brain activity between the two working memory tasks revealed no differences within the lateral prefrontal cortex, whereas the premotor area was more active during the spatial working memory task. Comparing the delay‐specific activity, which did not include task‐associated stimulus/response‐related activity, revealed more spatial working memory‐related activity in the posterior parietal and premotor areas, and more non‐spatial working memory‐related activity in the dorsolateral prefrontal cortex and hippocampus. These results suggest that working memory in the monkey brain is segregated based on domain, not within the lateral prefrontal cortex but rather between the posterior parietal‐premotor areas and the dorsolateral prefrontal‐hippocampus areas.
The Pricing of Corporate Foreign Sales Risk

We test the pricing of foreign sales exposure risk using the ratio of the firm foreign sales to total sales (FSratio). Whereas foreign-exchange exposure is not priced, foreign sales exposure is priced both as a characteristic and as systematic risk. Across stocks, return increases in FSratio and the risk-adjusted excess return (alpha) on high-minus-low-FSratio stocks (HMLFS) is positive. The HMLFS systematic risk – βHMLFS – captures firms’ direct and indirect exposures to foreign sales, even for firms that have no direct foreign sales. Expected stock returns increase in βHMLFS in a Fama-Macbeth analysis after controlling for other factors’ beta risk.
Desktop data sonification: Comments on Flowers et al., ICAD 1996

Sonification tools have not yet become typical components of data analysis software, despite dramatic advances in sound-production capabilities of personal computers over the past decade. However, we continue to believe that auditory displays have the potential to be highly useful for “small scale” exploration of data for normally sighted users as well as an alternative format for users with visual impairment. Demonstration of effective examples of auditory data displays and design of flexible software tools for data sonification will be key factors in determining the impact of this method of data representation.
Strategic Database Marketing: The Masterplan for Starting and Managing a Profitable, Customer-Based Marketing Program

Part 1: Database Marketing and the Web. Strategic Database Marketing and the Web: An Overview. "The Vision Thing". Part 2: Strategy Development. Lifetime Value - The Criterion of Strategy. Designing a Successful Cutomer Strategy. Building Profits with Recency, Frequency, and Monetary Analysis. Communicating with Customers. Building Customer Loyalty. Using Customer Profiles in Marketing Strategy. Strategy Verification: Testing and Control Groups. Finding Customers through the Web. Part 3: Profiting by Experience. Retailing and Packaged Goods. Building Retention and Loyalty in Business Customers. Financial Services. Why Databases Fail. Database Types That Succeed. Choosing Business Partners. Database Marketing and the Internal Struggle for Power A Farewell to the Reader.
STUDY ON SHOPPING STYLES OF YOUNG SHOPPERS A study with reference to young shoppers in Kerala

Abstract Organized retailing is changing the whole concept of shopping, creating a radical shift in consumer buying behavior. In such a scenario, understanding consumer’s shopping styles and preferences is considered to be very crucial in order to succeed in selling a product or service. Consumer shopping styles is a major area of concern for marketers as it provides the advantage of aligning the sales techniques with the buying style, which improves the chances of converting more prospects to paying customers. Today, the market is driven by the changing consumption patterns and aspirations of the youth. Young consumers show more consumer confidence, are active and spend more than they save. They represent a powerful new consumer force and shape the trends that affect the modern retail sector. Moreover, there exists considerable difference in the shopping styles exhibited by urban, semi-urban and rural consumers. The purpose of this study was to investigate the difference in shopping styles of young urban and semi-urban consumers in Kerala, India and to analyze the consumer shopping styles across different demographic variables. Data for this study were collected from 220 students in Kerala, who frequently shop from modern retail outlets. The study revealed that there exist statistically significant differences in the shopping styles of urban and semi-urban consumers. The consumer shopping styles also vary across demographic variables. This study will help marketers to understand the young shoppers in terms of their shopping styles and to adapt and improve their marketing campaigns as well as strategies to penetrate more into the market. Key words: Consumer shopping styles, Consumer Style Inventory (CSI), Young shoppers.
Localization of MglA, an essential gliding motility protein in Myxococcus xanthus

MglA, a 22‐kDa protein related to monomeric GTPases, is required for the normal operation of the A (Adventurous) and S (Social) motility and for multicellular development of Myxococcus xanthus. To determine how MglA controls A‐ and S‐motility, MglA was assayed biochemically and its cellular location was determined. His‐tagged MglA hydrolyzed GTP slowly in vitro at a rate nearly identical to that of Ras showing that MglA has GTPase activity. Immunofluorescence microscopy of fixed cells from liquid showed that MglA was associated with helical track similar to the MreB spiral that spanned the length of the cell. The distribution pattern of MglA depended on the type of surface from which cells were harvested. In cells gliding on 1.5% (w/v) agar, the helical pattern gave way to punctate clusters of MglA‐Yfp at the poles and along the long axis (lateral clusters). The lateral clusters emerged near the leading pole as the cell advanced coincident with a decrease in the intensity of the MglA‐Yfp cluster at the leading pole. Newly formed lateral clusters remained fixed with regard to the substratum as the cell moved forward, similar to focal adhesion complexes described for AglZ, a protein partner of MglA. Lateral clusters did not form in cells gliding in methylcellulose, a polymer that stimulates S‐motility at low cell density; rather MglA‐Yfp was diffuse in the cytoplasm and more concentrated at the poles. The results suggest that conditions that favor S‐motility prevent the formation of lateral clusters of MglA, which are associated with A‐motility functions. © 2010 Wiley‐Liss, Inc.
Intellectual disability (mental retardation).

1. Sarah E. Shea, MD, FRCPC* 1. *Editorial board member; Dalhousie University, Halifax, Nova Scotia. * Abbreviations: AAIDD: : American Association on Intellectual and Developmental Disabilities ADHD: : attention-deficit/hyperactivity disorder CT: : computed tomography DSM: : Diagnostic and Statistical Manual of Mental Disorders FAPE: : free appropriate public education FAS: : fetal alcohol syndrome ID: : intellectual disability IQ: : intelligence quotient MR: : mental retardation The approach to genetic testing in the evaluation of intellectual disability is changing with the introduction of newer techniques, such as microarray testing. After reading this article, readers should be able to: 1. Understand the terminology and definitions relevant to individuals who are intellectually disabled. 2. Be aware of the epidemiology, clinical presentations, and causes of intellectual disability (ID). 3. Know how to carry out an evaluation for the cause of a child's ID, realizing that in many cases a cause cannot be identified, and know how to assess the child's strengths and weaknesses. 4. Be aware of the latest trends in genetic testing in identifying the causes of ID. 5. Know the conditions that commonly coexist with ID and know proper medical follow-up. 6. Understand what is involved in the education of children and adolescents with ID, as well as reasonable expectations. 7. Be aware of ways to help an intellectually disabled youth transition to adulthood. Intellectual disability is a general term for what has previously been described as mental retardation. ID is a lifelong condition characterized by significant impairment of cognitive and adaptive development owing to abnormalities of brain structure or function. ID is not a single entity, but rather a general symptom of neurologic dysfunction. At this time, the terminology used with respect to intellectual disability (ID) (mental retardation [MR]) is shifting. The term mental retardation is still in use in many settings, including by some clinicians, and is found in legal and public policies that determine eligibility for support; however, the use of the term intellectual disability as a direct substitute for mental retardation is increasing. The American Association on Mental Retardation has been renamed …
Non-Abelian gapless and quasi-gapless excitations of vortices in condensed matter systems

We discuss the low energy effective theory of gapless excitations of the mass vortices of systems similar to the Ginzburg–Landau description of superfluid helium-3 in the bulk B-phase. Our approach is to determine the vortex solution by considering a specific ansatz for the order parameter and minimizing the free energy. The conditions on the βi coefficients required for the stability of the various solutions for the order parameter are calculated. By considering the symmetries that are broken by the vortex solutions we are able to generate the modulus fields associated with the low energy excitations of the vortices. Using these fields we determine the effective free energy describing the dynamics of these excitations.
Significance of group delay functions in spectrum estimation

A method of spectrum estimation using group delay functions is proposed. This method exploits the additive property of the Fourier transform (FT) phase to extract spectral information of the signal in the presence of noise. The phase is generally featureless due to random polarity and wrappings, but the group delay function can be processed to derive significant information such as peaks in the spectral envelope. In the resulting spectral estimates obtained the resolution properties of the periodogram estimate are preserved while the variance is reduced. Variance caused by the sidelobe leakage due to windows and additive noise are significantly reduced even in the spectral estimate obtained using a single realization of the observation peak. Resolution is primarily dictated by the size of the data window. The method works even for high noise levels. The results of this procedure are demonstrated through two illustrative examples: estimation of sinusoids in noise and estimation of the narrowband autoregressive process in noise. >
The Development of Capabilities of Young People with Low Skills. The Case Study of a Vocational Education Programme in Poland.

The article presents results of a case study of educational programme, which was designed to answer the structural problems of vocational schooling in Poland. It aimed at improving skills of students from vocational schools and was provided by a big employer operating in the sector of power industry. The analysis of empirical material consisting of interviews, documents, legal regulations and statistics, focused on identifying factors working in favour of building capabilities of its participants (increasing spectrum of their possible life choices). This particular case study gives insight into more general mechanisms contributing to the development of freedom of youth with low skills or impeding it by reproduction of inequalities.
Strains on Money Market Makers and Money Market Liquidity

We analyze the trading book of a key market maker in the European unsecured money market and study the extent to which liquidity risks accumulated by this market maker affect his pricing of liquidity and the bid-ask-spread he quotes on unsecured borrowing and lending. We find that the larger the funding liquidity risk assumed by the market maker the higher the market price for liquidity and the higher his term premium. Furthermore, his bid-ask-spread and the sensitivity of his bid-ask-spread to the maturity of transactions increases as his assumed liquidity risk rises. This suggests that also in the unsecured money market funding constraints and funding risks of the market maker affect market liquidity in line with Gromp and Vayanos (2004) and Brunnermeier and Pedersen (2009).
Signal processing and climate understanding

Clean energy, as generated by wind and sun, is a must nowadays. It has, however, to be competitive with other sources, offering acceptable costs and production risks. This work faces the usual lack of a long and reliable historic of climato-logical data and consequent uncertainty about expected plant production. Customized machine learning and signal processing techniques are used to map regional satellite measurements into local information, creating a virtual historical series of energy production. Two illustrative cases are presented for eolic and photovoltaic energy, where neural network inputs and operations are described.
Review of the genus Canalirogas van Achterberg & Chen (Hymenoptera, Braconidae, Rogadinae) from Vietnam, with description of ten new species

Abstract The Vietnamese species of the genus Canalirogas van Achterberg & Chen, 1996 (Hymenoptera: Braconidae: Rogadinae) are revised. Ten species are new to science, viz., Canalirogas affinis sp. n. , Canalirogas cucphuongensis sp. n. , Canalirogas curvinervis sp. n. , Canalirogas eurycerus sp. n. , Canalirogas hoabinhicus sp. n. , Canalirogas intermedius sp. n. , Canalirogas parallelus sp. n. , Canalirogas robberti sp. n. , Canalirogas vittatus sp. n. and Canalirogas vuquangensis sp. n. One species is new for the Vietnamese fauna: Canalirogas spilonotus (Cameron, 1905) and Canalirogas balgooyi van Achterberg & Chen, 1996, is synonymized with it (syn. n.); a lectotype is designated for Troporhogas spilonotus. A key to the Vietnamese species of the genus is also provided.
Reduction in Smad 2 / 3 Signaling Enhances Tumorigenesis but Suppresses Metastasis of Breast Cancer Cell Lines

The role of transforming growth factor in breast cancer is controversial with tumor suppressor and pro-oncogenic activities having been demonstrated. To address whether the same or different signal transduction pathways mediate these opposing activities, we manipulated the Smad2/3 signaling pathway in cells of common origin but differing degrees of malignancy derived from MCF10A human breast cells. We show that interference with endogenous Smad2/3 signaling enhances the malignancy of xenografted tumors of premalignant and well-differentiated tumor cells but strongly suppresses lung metastases of more aggressive carcinoma cells after tail vein injection. Overexpression of Smad3 in the same cells has opposite effects. The data demonstrate that the Smad2/3 signaling pathway mediates tumor suppressor and prometastatic signals, depending on the cellular context.
Invasive and Noninvasive Mechanical Ventilation For Acute Exacerbations Of Chronic Obstructive Pulmonary Disease: A Comparative Study.

Introduction: Acute exacerbation of chronic obstructive pulmonary disease (COPD) is a frequent cause of hospitalization and intensive care unit admission. Respiratory failure from airflow obstruction is a direct consequenceof acute airway narrowing.Aim of the study: It was to compare the efficacy of noninvasive mechanical ventilation (NIMV) against conventional mechanical ventilation (CMV) in patients with acute exacerbation of COPD. Patients and methods: Forty patients with acute exacerbation of COPD were recruited in the present study. A comparative, hospital based study design was used. All the cases were examined; clinically and laboratory. The patients were divided into two groups each include 20 patients. Group A received NIMV in the form of continuous positive airway pressure (CPAP) and group B with CMV. Results: There were statistically significant decreases in respiratory rate, heart rate and diastolic blood pressure after 6 hours of CPAP in comparison to baseline parameters in group A. While, there were statistically significant increases in PaO2 and SaO2 after 6 hours of CPAP in comparison to baseline parameters. In group B there were statistically significant decreases in respiratory rate, heart rate, systolic blood pressure and diastolic blood pressure after 6 hours of CMV in comparison to baseline parameters. While, there were statistically significant increases in pH, PaO2, and SaO2 and a statistically significant decrease in PaCO2 after 6 hours of CMV in comparison to baseline parameters. Further, comparison of respiratory rate and hemodynamic parameters in both groups showed statistically significant decreases in respiratory rate, heart rate, systolic blood pressure and diastolic blood pressure in group A in comparison to group B. Finally, failure rate was 35.0% in group A (NIMV) compared to 5.0% in group B (CMV) with statistically significant difference. Conclusions and recommendations: Noninvasive mechanical ventilation is a safe and effective means of improving gas exchange in patients with acute exacerbations of CPPD. If patient not respond to NIMV, CMV should be used. Further studies are needed to evaluate the appropriate selection of patients and to find the best level and schedule of ventilation.