Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of switching unfractionated heparin to low-molecular-weight heparin on serum potassium in hemodialysis patients.

INTRODUCTION Unfractionated (UF) heparin is the most common anticoagulant used during hemodialysis. Failure of the kidneys to excrete potassium as well as heparin-induced reduction of aldosterone synthesis put hemodialysis patients at risk of hyperkalemia. It has not yet been clearly known whether hyperkalemia is also induced by low-molecular-weight (LMW) heparins. This study aimed to evaluate the effect of switching UF heparin to LMW heparin enoxaparin, as an anticoagulant during hemodialysis, on serum potassium level in patients on hemodialysis. MATERIAL AND METHODS In two hemodialysis units, 58 patients were randomly assigned into two groups, to receive two different anticoagulation protocols for 3 weeks; one group continued to receive their routine dose of UF heparin, 5000 units, and the other received enoxaparin, 0.5 mg/kg, at the beginning of each hemodialysis session. RESULTS While there was no significant difference between baseline blood measurements of the two groups in terms of kidney function tests and electrolytes, following 3 weeks of the study, the mean serum potassium level decreased from 4.9 ± 0.8 mEq/L to 4.5 ± 0.5 mEq/L in the LMW heparin group (P = .001); however, there was no change in the mean serum potassium level in those who continued to receive their usual dose of UF heparin. In a subgroup analysis, diabetic patients in the enoxaparin group did not experience significant reduction in serum potassium levels. CONCLUSIONS Our study revealed the role of LMW heparins as a potential alternative to UF heparins in the hemodialysis patients with hyperkalemia.
The business potential of live communication in the European Union : a market analysis of the European Union’s outsourced event and communication actions

This commissioned thesis examines the business potential of live communication in the European Union. The commissioner of the study is the Live Communication agency 27Names. Live communication is an innovative sector of the event industry entailing the face-to-face and online goal-directed visitations between the communication owner and target audience. The study examines the current utilization of live communication in the EU, the competitive field targeting to the institutional projects and the business possibilities the European Union is offering for the live communication agencies. The theoretical framework of the study contains the knowledge of the current communication actions of the European Union, the procurement procedures and the features of the competitive environment. The main sources of the research were the qualitative customer survey and the comprehensive study of the customer and competitors. The final outcome of the thesis entails a market analysis with two segments: the customer analysis and the competitor analysis. The analyses offer an extensive view to the business potential of live communication and to the current competitive environment targeting the EU projects. The main findings indicate that the business potential of live communication in the European Union is remarkable. There are versatile working possibilities for live communication companies. However, the projects also contain several rules and directives that must be obeyed. The competitive environment targeting to the EU projects is extremely intense. There are many experienced agencies competing with the commissioning company. Despite the strong competitors, 27Names has great possibilities to gain success in the institutional projects. The outcome of the thesis can be applied to the entire event and live communication business sector in Europe.
Credit Derivatives in an Affine Framework ( Working Paper Version )

A general and efficient method for valuing credit derivatives based on multiple entities is developed in an affine framework. This includes interdependence of market and credit risk, joint credit migration and counterparty default risk of multiple firms. As an application we provide closed form expressions for the joint distribution of default times, default correlations, and default swap spreads in the presence of counterparty default risk. An extension of this framework towards modeling default correlations of a large credit portfolio is also discussed.
Denoising of hyperspectral images using shearlet transform and fully constrained least squares unmixing

In this paper, we propose a new denoising method based on a 2D non-subsampled shearlet transform (NSST) and fully constrained least squares unmixing (FCLSU). In the proposed method, first low noisy (LN) bands are separated from high noisy (HN) bands using spectral correlation. Second, NSST is applied to each spectral band of the hyperspectral images. Third, LN bands are denoised using a thresholding technique on the shearlet coefficients and HN bands are denoised by applying FCLSU. The proposed method is compared to state of the art denoising methods on synthetic and real hyperspectral datasets. The effect of denoising on classification accuracy is also investigated. Obtained results show the superiority of the proposed approach.
Development and Implementation of a Performance Management System that Efficiently and Effectively Drive Thai Public Sector Development

This thesis investigates how the Thai public sector, particularly at the provincial level, makes sense of the performance management system (PMS) aimed at driving forward the improvement in public service and enhancing the sustainability of service quality. The study explores the implications of the PMS implementation after the major civil service reform in 2002. The core aspects of this development include the nation-wide implementation of the PMS, the Provincial CEO scheme, as well as the incentive schemes put force to motivate and enhance such development and improvement. Although there is rich literature on performance management, there is limited in the Thai context, particularly at the provincial level. The empirical study relies on a qualitative approach through intensively exploring five provincial case studies. In-depth, semi-structure interviews have been conducted within the provinces, as well as with executives from central agencies, training and development institutes, and key resource persons who are directly involved in the PMS implementation. The data analysis reveals that a strong commitment of the government at policy level brought in support and coordination among central agencies and has altered attention and resources towards the system implementation. Additionally, the PMS implementation together with the promotion of the Provincial CEO scheme has created new challenges for the Provincial Governors and the provincial administration in which there is shown to be a shift from an administrative approach to a more managerial and participative one. The performance agreement (PA) has played a crucial role in improving and evaluating performance, driving public sector development, and linking performance with the monetary incentive schemes. However, the study also finds a limitation of the PA execution in relation to its linkages with incentive distribution to individuals. Furthermore, several incentive schemes are available for different groups of people and cause misunderstanding and demotivating affects which, in turn, has impacts on the PMS as a whole.The findings of this research provide new evidence on the PMS implications at the provincial level in the Thai public sector in which political policies are cascaded down into real practices and execution. Therefore, the result could be considered as extending the knowledge boundary in the context of public management. Crucially, the research highlights significant implications and specified factors enabling and inhibiting success in the PMS implementation.
Development and Validation of Colorimetric and RP - HPLC Methods for the Determination of Formaldehyde in Cosmetics

Aims: To develop and validate two assay methods for the determination of total and free formaldehyde content in cosmetics by Colorimetric and High Performance Liquid Chromatographic (HPLC) methods, respectively. Study Design: Colorimetric and HPLC methods. Place and Duration of Study: Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh; between February 2012 and June 2013. Short Research Article Rahman et al.; ACSj, 5(3): 224-237, 2015; Article no.ACSj. 2015.022 225 Methodology: In Colorimetric method the quantitation was performed by a UV/Vis spectrophotometer at 410 nm and by HPLC at 345 nm and the methods were linear over the concentration ranges of 4-12 mg/L (R 2 =0.999) and 2-32 mg/L (R 2 =0.999), respectively. Based on 2, 4-dinitrophenylhydrazine (DNPH) derivatization, free formaldehyde was analyzed using a Phenomenex C18 (250 mm × 4.6 mm i. d., 5 μm particle size) column in a binary separation mode with mobile phase consisting of acetonitrile and distilled water (45:55, v/v) and flow rate of 2.0 mL/min. Results: The overall recovery rate of free formaldehyde was (95.33-98.37)±(0.29-1.6)% (RSD). Seventy five cosmetics of local and foreign brands were investigated. None of those products was labeled to contain formaldehyde. 18 products were labeled with specific formaldehyde donors (17 with DMDM hydantoin and 1 with imidazolidinyl urea). 64% of the products were formaldehyde positive among which 54% exceeded 0.05% limit of formaldehyde content for which EU dictates the mandatory formaldehyde donors labeling. The investigated amounts of the total formaldehyde and free formaldehyde were 190-5502 mg/L and 47-604 mg/L, respectively. Conclusion: The methods were found valid as per in terms of suitability, linearity, accuracy, sensitivity, ruggedness, and robustness. The formaldehyde content found in the cosmetics was highly alarming and must be addressed by the authority in an immediate basis.
Aporosa tetragona Tagane & V. S. Dang (Phyllanthaceae), a new species from Mt. Hon Ba, Vietnam

Abstract A new species, Aporosa tetragona Tagane & V. S. Dang, sp. nov., is described and illustrated from Mt. Hon Ba located in the Khanh Hoa Province, South Vietnam. This species is characterized by tetragonal pistillate flowers and fruits, which are clearly distinguishable from the other previously known species of the genus. The morphology and phylogeny based on rbcL and matK of this species indicated that the new species belongs to section Appendiculatae Pax & K. Hoffm.
Not If Affordability Data Adds Value But How to Add Real Value by Leveraging Affordability Data: Enhancing Predictive Capability of Credit Scoring Using Affordability Data

The aim of this paper is to focus on the role of affordability of loans on credit risk at 3 different levels. The first being short term practical approach to optimally using affordability data to improve current credit scorecards by showing how Random Forests can be used to improve logistic regression. After this discussion we step back and look at how affordability fits into ensuring systemic risk and use the credit union industry as a base case model for using affordability measures to reduce systemic risk. Finally we turn to the question of whether credit risk is a source of sustainable competitive advantage and what measures would create greater welfare for the financial system as whole. It is the belief of the authors that proprietary black box credit systems and increasing complexity of unpredictable factors make it necessary to build an open credit systems viewpoint. Using this weltanschauung we conclude with a simple example of restructuring mortgage products using affordability and borrower well being as central to sustainable credit risk management. The article is comprised of survey and quantitative analysis showing how affordability has been used in the credit industry or not used. The article shows that credit decisions can be improved by leveraging affordability optimally and then also discusses policy implications of using affordability to ensure soundness and well being of consumers instead of simply determining whether the consumer will repay the loan successfully.
Conjecturas Acerca do Gerenciamento de Lucros, Republicação das Demonstrações Contábeis e Fraude Contábil

Financial statement reporting objectives to inform external users about the financial situation of an organization. However, recent fraud scandals involving highly known corporations (Enron, WorldCom, Adelphia, Xerox, Parmalat, etc.) have led financial statement's users to question the integrity and the credibility of this information. This paper, which adopts an exploratory approach, objectives to discuss and to define a few issues related to the manipulation of accounting information: earnings management, financial restatement and fraudulent reporting. For these, a literature review has been. This paper's main contribution consists in the discussion of a theme, which is an organization's "real" problem, and yet incipient in the brazilian scientific literature.
Interactive Shape Design

Providing an intuitive modeling system, which would enable us to communicate about any free-form shape we have in mind at least as quickly as with real-world tools, is one of the main challenges of digital shape design. The user should ideally be able to create, deform, and progressively add details to a shape, without being aware of the underlying mathematical representation nor being tied by any constraint on the geometrical or topological nature of the model. This book presents the field of interactive shape design from this perspective. Since interactively creating a shape builds on the humans ability of modeling by gesture, we note that the recent advances in interactive shape design can be classified as those that rely on sculpting as opposed to sketching metaphors. Our synthetic presentation of these strategies enables us to compare the different families of solutions, discuss open issues, and identify directions for future research. Table of Contents: Introduction / Sculpting etaphors / Sketching Systems / Future Directions: Modeling by Gesture
PENGARUH GOOD CORPORATE GOVERNANCE DAN KINERJA PERUSAHAAN TERHADAP NILAI PERUSAHAAN (Studi Pada Badan Usaha Milik Negara Yang Terdaftar Di Bursa Efek Indonesia Tahun 2010-2013)

Competition of the business world today's is very tight so its realy ne ed to implementation the good corporate governance. Implementation of the good corporate governance can improve the performance of the company. High performance of enterprise will have an impact on the value of the company. The study of aims to identify and explain the influence of good corporate governance to corporate value, identify and explain the effect of the performance of the company to the value of the company and identify and explain the influence of good corporate governance and co mpany performance against the value of the company. This type of research is explanatory research with quantitative approach. Based on the analysis of the partial result obtained in the form of good corporate governance has no effect on the value of the company, the company's performance effect the value of the company. The result from the Simultaneous analysis of the obtained results that good corporate governance and company performance effect on the value of the company. Keyword : Good Corporate Govvernance, Company Performance, Company Value ABSTRAK Persaingan dunia bisnis saat ini sangat ketat sehingga perlu adanya tata kelola perusahaan yang baik atau Good corporate governance . Penerapan good corporate governance dapat meningkatkan kinerja perusahaan. Kinerja perusahaan yang tinggi akan berdampak pada nilai perusahaan. Penelitian ini bertujuan untuk mengetahui dan menjelaskan pengaruh good corporate governance terhadap nilai perusahaan, mengetahui dan menjelaskan pengaruh kinerja perusahaan terhadap nilai perusahaan serta mengetahui dan menjelaskan pengaruh good corporate governance dan kinerja perusahaan terhadap nilai perusahaan. Jenis penelitian yang digunakan ialah penelitian penjelasan dengan pendekatan kuantitatif. Berdasarkan analisis secara parsial diperoleh hasil berupa good corporate governance tidak berpengaruh terhadap nilai perusahaan, kinerja perusahaan berpengaruh terhadap nilai perusahaan. Hasil dari analisis simultan diperoleh hasil bahwa good corporate governance dan kinerja perusahhan berpengaruh terhadap nilai perusahaan. Kata Kunci : good corporate governance , kinerja perusahaan, nilai perusahaan
A grid-based approach to automating display layout

A research testbed is described for exploring the automated layout of graphical displays. We address the problem of determining the size and position of the objects displayed to a user. Our approach is based on the graphic design concept of a design grid. A design grid is a set of proportionally-spaced vertical and horizontal lines that control the position and size of the objects being laid out. The system first generates a grid intended for a set of possible displays, based on information about the kind of material to be displayed, the user, and the display hardware. The grid is next used, in conjunction with further information about the kinds of objects to be presented, to create a prototype display layout. This prototype display layout determines how each actual set of objects will be sized and positioned in the displays presented to the user.
Enoxaparin versus unfractionated heparin with fibrinolysis for ST-elevation myocardial infarction.

BACKGROUND Unfractionated heparin is often used as adjunctive therapy with fibrinolysis in patients with ST-elevation myocardial infarction. We compared a low-molecular-weight heparin, enoxaparin, with unfractionated heparin for this purpose. METHODS We randomly assigned 20,506 patients with ST-elevation myocardial infarction who were scheduled to undergo fibrinolysis to receive enoxaparin throughout the index hospitalization or weight-based unfractionated heparin for at least 48 hours. The primary efficacy end point was death or nonfatal recurrent myocardial infarction through 30 days. RESULTS The primary end point occurred in 12.0 percent of patients in the unfractionated heparin group and 9.9 percent of those in the enoxaparin group (17 percent reduction in relative risk, P<0.001). Nonfatal reinfarction occurred in 4.5 percent of the patients receiving unfractionated heparin and 3.0 percent of those receiving enoxaparin (33 percent reduction in relative risk, P<0.001); 7.5 percent of patients given unfractionated heparin died, as did 6.9 percent of those given enoxaparin (P=0.11). The composite of death, nonfatal reinfarction, or urgent revascularization occurred in 14.5 percent of patients given unfractionated heparin and 11.7 percent of those given enoxaparin (P<0.001); major bleeding occurred in 1.4 percent and 2.1 percent, respectively (P<0.001). The composite of death, nonfatal reinfarction, or nonfatal intracranial hemorrhage (a measure of net clinical benefit) occurred in 12.2 percent of patients given unfractionated heparin and 10.1 percent of those given enoxaparin (P<0.001). CONCLUSIONS In patients receiving fibrinolysis for ST-elevation myocardial infarction, treatment with enoxaparin throughout the index hospitalization is superior to treatment with unfractionated heparin for 48 hours but is associated with an increase in major bleeding episodes. These findings should be interpreted in the context of net clinical benefit. (ClinicalTrials.gov number, NCT00077792.).
Insurance Culture in China under the Conditions of Transformation

During the process of transformation from Gemeinschaft to Gesellschaft, as a product of market economy, China's insurance industry has achieved great accomplishments since its reestablishment in 1980. However, it still encounters the problem of the low acceptance rate among Chinese people. They have their own understanding of insurance according to their knowledge of insurance. Chinese attitudes towards insurance are less positive. For those Chinese who have purchased commercial insurance, their insurance behavior displays the influences of culture. Facing insurance? one method of dealing with risks, Chinese people like to compare it with the traditional mode of dealing with risks which is composed of family, human relationships, and work unit (country), which cultural foundation is the traditional values including "loyalty, filial piety, and ties of friendship". Although there have been many changes of the traditional mode of dealing with risks because of the transformation, the traditional mode is still operating. The cultural values-"loyalty, filial piety, and ties of friendship"-dominate Chinese people's attitudes towards insurance and their insurance behavior. This paper discusses the influence of these values on the development of insurance in China.
The Past Tense Debate Revisited: Electrophysiological Evidence for Subregularities of Irregular Verb Inflection

Neuropsychological research investigating mental grammar and lexicon has largely been based on the processing of regular and irregular inflection. Past tense inflection of regular verbs is assumed to be generated by a syntactic rule (e.g., show-ed), whereas irregular verbs consist of rather unsystematic alternations (e.g., caught) represented as lexical entries. Recent morphological accounts, however, hold that irregular inflection is not entirely rule-free but relies on morphological principles. These subregularities are computed by the syntactic system. We tested this latter hypothesis by examining alternations of irregular German verbs as well as pseudowords using ERPs. Participants read series of irregular verb inflection including present tense, past participle, and past tense forms embedded in minimal syntactic contexts. The critical past tense form was correct (e.g., er sang [he sang]) or incorrect by being either partially consistent (e.g., *er sung [*he sung]) or inconsistent (e.g., *er sing [*he sing]) with the proposed morphological principles. Correspondingly, in a second experimental block, pseudowords (e.g., tang/*tung/*ting) were presented. ERPs for real words revealed a biphasic ERP pattern consisting of a negativity and P600 for both incorrect forms in comparison to the correct equivalents. Most interestingly, the P600 amplitude for the incorrect forms was gradually modulated by the type of anomaly with medium amplitude for consistent past tense forms and largest amplitude for inconsistent past tense forms. ERPs for pseudoword past tense forms showed a similar gradual modulation of N400. The findings support the assumption that irregular verbs are processed by rule-based mechanisms because of subregularities of their past tense inflection.
Phospholipase Cγ2 Contributes to Light-Chain Gene Activation and Receptor Editing

ABSTRACT Phospholipase Cγ2 (PLCγ2) is critical for pre-B-cell receptor (pre-BCR) and BCR signaling. Current studies discovered that PLCγ2-deficient mice had reduced immunoglobulin λ (Igλ) light-chain usage throughout B-cell maturation stages, including transitional type 1 (T1), transitional type 2 (T2), and mature follicular B cells. The reduction of Igλ rearrangement by PLCγ2 deficiency was not due to specifically increased apoptosis or decreased proliferation of mutant Igλ+ B cells, as lack of PLCγ2 exerted a similar effect on apoptosis and proliferation of both Igλ+ and Igκ+ B cells. Moreover, PLCγ2-deficient IgHEL transgenic B cells exhibited an impairment of antigen-induced receptor editing among both the endogenous λ and κ loci in vitro and in vivo. Importantly, PLCγ2 deficiency impaired BCR-induced expression of IRF-4 and IRF-8, the two transcription factors critical for λ and κ light-chain rearrangements. Taken together, these data demonstrate that the PLCγ2 signaling pathway plays a role in activation of light-chain loci and contributes to receptor editing.