Miracle-dz/UniFAR-FTUs huggingface dataset:
L 2 SERRE DUALITY ON DOMAINS IN COMPLEX MANIFOLDS AND APPLICATIONS

An L 2 version of the Serre duality on domains in complex manifolds involving duality of Hilbert space realizations of the @-operator is established. This duality is used to study the solution of the @-equation with prescribed support. Applications are given to @-closed extension of forms, as well to Bochner-Hartogs type extension of CR functions. comp (;E � ) with the quotient topology, where we endow spaces of compactly supported forms with the natural inductive limit topology. In fact, condition that the two maps in (1) have closed range is also necessary for the duality theorem to hold (see (9); also see (26, 27, 28) for further results of this type. ) Serre's original proof (33) is based on sheaf theory and the theory of topological vector spaces. A different approach to this result, in the case when is a compact complex manifold, was given by Kodaira using Hodge theory (see (23) or (7). ) In this note we extend Kodaira's method to non-compact Hermitian manifolds to obtain an L 2 analog of the Serre duality. Special cases of Serre-duality using L 2 methods have appeared before in many contexts (see (25), or (11, Theorem 5.1.7) and (19, 20), for example. ) Our treatment aims to streamline and systematize these results, with emphasis on non-compact manifolds, and point out its close relation with the choice of L 2 -realizations of the Cauchy-Riemann operator @, or alternatively, choice of boundary conditions for the L 2 -realizations of the formal complex Laplacian @E#E + #E@E. The L 2 -duality can be interpreted in many ways. At one level, it is a duality between the standard � - Laplacian with @-Neumann boundary conditions, and thec-Laplacian with dual ( "@-Dirichlet") boundary conditions. Using another approach, results regarding solution of the @-equation in L 2 can be converted to statements regarding the solution of the @c equation. This leads to a solution of the @-Cauchy problem, i.e., solution of the @-equation with prescribed support. At the heart of the matter lies the existence of
Lectin electron microscopic histochemistry of the pseudoexfoliative material in the skin.

PURPOSE To investigate the hypothesis that pseudoexfoliation (PSX) syndrome is a systemic disorder, the authors studied the composition of glycoconjugates in the intraocular and extraocular PSX material at the electron microscopic level, using a panel of lectins as cytochemical probes. METHODS The authors examined 8 lid skins, 11 trabecular tissues, and 3 cataractous lenses from human eyes with PSX syndrome. Tissues were processed for electron microscopical histochemistry and stained with PNA, RCA120, DBA, SBA, ConA, WGA, UEA-I, and Lotus, with an indirect lectin-colloidal gold technique. RESULTS Both the intraocular and extraocular PSX materials manifested almost identical reactivity to lectins, which indicated that glycoconjugates in the PSX material contained with sugar residues of galactose (PNA, RCA120), alpha-mannose (ConA), and N-acetyl-D-glucosamine (WGA). On the other hand, it was indicated that sugar residues of N-acetyl-D-galactosamine (DBA, SBA) and fucose (UEA-I, Lotus) were absent. Granular inclusions and microfibrils in the capsule and ocular zonules were stained similarly and weakly. CONCLUSIONS The intraocular and extraocular PSX materials contained the same sugar residues of glycoconjugates, which suggested that those materials had the same nature. This study, the first documentation of lectin-binding sites on the extraocular PSX material, supported the hypothesis of PSX syndrome as a systemic disorder.
Stratospheric Observations of CH3D and HDO from ATMOS Infrared Solar Spectra: Enrichments

Stratospheric mixing ratios of CH_3D from 100 mb to 17 mb (≈ 15 to 28 km) and HDO from 100 mb to 10 mb (≈ 15 to 32 km) have been inferred from high resolution solar occultation infrared spectra from the Atmospheric Trace MOlecule Spectroscopy (ATMOS) Fourier-transform interferometer. The spectra, taken on board the Space Shuttle during the Spacelab 3 and ATLAS-1, -2, and -3 missions, extend in latitude from 70°S to 65°N. We find CH_3D entering the stratosphere at an average mixing ratio of (9.9±0.8) × 10^(−10) with a D/H ratio in methane (7.1±7.4)% less than that in Standard Mean Ocean Water (SMOW) (1σ combined precision and systematic error). In the mid to lower stratosphere, the average lifetime of CH_3D is found to be (1.19±0.02) times that of CH_4, resulting in an increasing D/H ratio in methane as air “ages” and the methane mixing ratio decreases. We find an average of (1.0±0.1) molecules of stratospheric HDO are produced for each CH_3D destroyed (1σ combined precision and systematic error), indicating that the rate of HDO production is approximately equal to the rate of CH_3D destruction. Assuming negligible amounts of deuterium in species other than HDO, CH_3D and HD, this limits the possible change in the stratospheric HD mixing ratio below about 10 mb to be ±0.1 molecules HD created per molecule CH_3D destroyed.
Magnetic resonance imaging of live freshwater mussels (Unionidae)

Abstract. We examined the soft tissues of live freshwater mussels, Eastern elliptio Elliptio complanata, via magnetic resonance imaging (MRI), acquiring data with a widely available human whole-body MRI system. Anatomical features depicted in the profile images included the foot, stomach, intestine, anterior and posterior adductor muscles, and pericardial cavity. Noteworthy observations on soft tissue morphology included a concentration of lipids at the most posterior aspect of the foot, the presence of hemolymph-filled fissures in the posterior adductor muscle, the presence of a relatively large hemolymph-filled sinus adjacent to the posterior adductor muscle (at the ventral-anterior aspect), and segmentation of the intestine (a diagnostic description not reported previously in Unionidae). Relatively little is known about the basic biology and ecological physiology of freshwater mussels. Traditional approaches for studying anatomy and tissue processes, and for measuring sub-lethal physiological stress, are destructive or invasive. Our study, the first to evaluate freshwater mussel soft tissues by MRI, clarifies the body plan of unionid mussels and demonstrates the efficacy of this technology for in vivo evaluation of the structure, function, and integrity of mussel soft tissues.
Feasibility and Impact of Doctor-Nurse Task Delegation in Preventive Child Health Care in the Netherlands, a Controlled Before-After Study

Background In the Netherlands a need is felt for more flexible Child Health Care services, both efficient and tailored to needs. We set up a study on impact and feasibility of task delegation to child health care nurses performing all regular checkups on children aged 2 months to 4 years. Abnormal findings were discussed with the attending child health care doctor. This article describes impact and feasibility of this task delegation from four viewpoints: competences of nurses; percentage of children assigned to the nurse; change in abnormal findings and referrals; experiences of professionals and parents. Methods Two experiment teams and two control teams were compared before and after starting task delegation. Nurses in the experiment teams were trained to carry out regular checkups on healthy children. Assignment to the experiment schedule was a joint decision by doctor and nurse. Nursing competences were measured by means of questionnaires. Percentage of children assigned to the nurse and screening results of eyes, heart, hips, growth and development were extracted from the electronic health record. Difference in change was compared between experiment and control teams. Mann-Whitney tests and logistic generalized estimating equations were used to test for significance. Experiences of professionals and parents were evaluated through focus group interviews, which were subjected to a qualitative analysis. Results Nurses in the experiment regions showed improvement in medical screening skills. No difference in change was perceived in general nursing competences. In the experiment group, 69% of all children were assigned to the nurse. There were no significant differences in change in the percentages of abnormal findings or referrals in the experiment teams compared to the control teams, except for hips. Interviews showed that both doctors and nurses thought positively of the new working method, yet made some recommendations for improvements. Parents felt well-informed and experienced an equal level of proficiency but less continuity in person. Conclusion This experiment shows that task delegation from doctor to nurse in preventive child health care is feasible. It is important to pay attention to the acceptation process of professionals during implementation. More investigation is needed in order to assess effectiveness and efficacy of task delegation.
Molecular Cloning and Characterization of Annexin V‐Binding Proteins with Highly Hydrophilic Peptide Structure

Abstract: We previously reported that annexin V promoted the survival of cultured rat neocortical neurons. In an effort to elucidate the mechanism underlying this neurotrophic activity of annexin V, we have attempted to identify the target or binding proteins of annexin V in neuronal cells. Herein, we screened an embryonic day 17 rat brain cDNA library by western blot using glutathione S‐transferase‐annexin V fusion protein as a probe and then isolated four clones showing binding to annexin V in a Ca2+ ‐ and phospholipid‐dependent manner. Although these cDNAs encoded different polypeptides, all four polypeptides shared the unique feature of containing highly hydrophilic stretches with high Lys, Glu, and Ser contents. Deduced amino acid sequences of two clones showed high homology with human X‐linked Helicase2 (XH2) and DNA (cytosine‐5) methyltransferase (DMTase) sequences, whereas the other two were not related to any known peptide sequence. These results suggest that XH2 and DMTase are candidates for annexin V‐binding proteins and thus may mediate the biological activity of annexin V.
Management of Madhumeha (Diabetes mellitus) with current evidence and intervention with Ayurvedic Rasausadhies

Rasausadhies or organo-metallic formulations have been use in the treatment of Diabetes mellitus with its excellence for centuries but their scientific evaluation has not thoroughly constituted with modern tools. Rasausadhies are popularly use since the period of great alchemist Nagarjuna, i.e. 8th century AD. In fact, it is explored that strategies and treatment modalities to control diabetes exists in Rasashastra, a discipline of Ayurveda. In this time, invention of special processing techniques as sodhan (purification and detoxification), marana (incineration), etc. have been established which are being use to convert the minerals and metals into easily consumable form and immediate showing the desirable effect. Madhumeha (Diabetes mellitus) is a multi-factorial disease resulting from a gene environment interaction. Projection of disease prevalence and incidence rate in worldwide by World Health Organization indicating the danger and graveness of this disease. In the present study, the initiation have been taken to collect and compiled all the related information about Madhumeha with current evidence regarding Rasausadhies used therapeutically that may facilitate further research work.
Mapping with MAV: Experimental Study on the Contribution of Absolute and Relative Aerial Position Control

This study highlights the benefit of precise aerial position control in the context of mapping using frame-based imagery taken by small UAVs. We execute several flights with a custom Micro Aerial Vehicle (MAV) octocopter over a small calibration field equipped with 90 signalized targets and 25 ground control points. The octocopter carries a consumer grade RGB camera, modified to insure precise GPS time stamping of each exposure, as well as a multi-frequency/constellation GNSS receiver. The GNSS antenna and camera are rigidly mounted together on a one-axis gimbal that allows control of the obliquity of the captured imagery. The presented experiments focus on including absolute and relative aerial control. We confirm practically that both approaches are very effective: the absolute control allows omission of ground control points while the relative requires only a minimum number of control points. Indeed, the latter method represents an attractive alternative in the context of MAVs for two reasons. First, the procedure is somewhat simplified (e.g. the lever-arm between the camera perspective and antenna phase centers does not need to be determined) and, second, its principle allows employing a single-frequency antenna and carrier-phase GNSS receiver. This reduces the cost of the system as well as the payload, which in turn increases the flying time.
Nuclear reprogramming in mammalian somatic cell nuclear cloning

Nuclear cloning is still a developing technique used to create genetically identical animals by somatic cell nuclear transfer into unfertilized eggs. Despite an intensive effort in a number of laboratories, the success rate of obtaining viable offspring from this technique remains less than 5%. In the past few years many investigators reported the reprogramming of specific nuclear activities in cloned animals, such as genome-wide gene expression patterns, DNA methylation, genetic imprinting, histone modifications and telomere length regulation. The results highlight the tremendous difficulty the clones face to reprogram the original differentiation status of the donor nuclei. Nevertheless, nuclei prepared from terminally differentiated lymphocytes can overcome this barrier and produce apparently normal mice. Study of this striking nuclear reprogramming activity should significantly contribute to our understanding of cell differentiation in more physiological settings.
Exploiting User Consuming Behavior for Effective Item Tagging

Automatic tagging techniques are important for many applications such as searching and recommendation, which has attracted many researchers' attention in recent years. Existing methods mainly rely on users' tagging behavior or items' content information for tagging, yet users' consuming behavior is ignored. In this paper, we propose to leverage such information and introduce a probabilistic model called joint-tagging LDA to improve tagging accuracy. An effective algorithm based on Zero-Order Collapsed Variational Bayes is developed. Experiments conducted on a real dataset demonstrate that joint-tagging LDA outperforms existing competing methods.
Enabling the Real-Time City: LIVE Singapore!

The increasing pervasiveness of urban systems and networks utilizing digital technologies for their operation generates enormous amounts of digital traces capable of reflecting in real-time how people make use of space and infrastructures in the city. This is not only transforming how we study, design, and manage cities but opens up new possibilities for tools that give people access to up-to-date information about urban dynamics, allowing them to take decisions that are more in sync with their environment. This paper documents the ongoing LIVE Singapore! project which explores the development of an open platform for the collection, elaboration and distribution of a large and growing number of different kinds of real-time data that originate in a city. Inspired by recent data.gov initiatives, the platform is structured to become itself a tool for developer communities, allowing them to analyze data and write applications that create links between a city's different real-time data streams, offering new insights and services to citizens. Being a compact island based city-state metropolis, Singapore offers a unique context for this study. This paper addresses the value of stream data for city planning and management as well as modalities to give citizens meaningful access to large amounts of data capable of informing their decisions. We describe the technology context within which this project is framed, illustrate the requirements and the architecture of the open real-time data platform to serve as a base for programming the city, and finally we present and discuss the first platform prototype (using real-world data from operators of cellphone networks, taxi fleet, public transport, sea port, airport, and others). Based on this prototype a public showcasing of the project was staged in April 2011 at the Singapore Art Museum and the visual data analytics generated are illustrated in the paper. Finally, we draw some conclusions of technical as well as organizational nature regarding the challenges we faced when working in new ways with real-world, real-time data streams in an urban context that will help inform further development of our as well as of related projects in progressing in disclosing the potential of the wealth of digital data generated by urban systems, networks, and infrastructures.
Fabrication of polymeric microfluidic devices with tunable wetting behavior for biomedical applications

We demonstrate the fabrication of microchannels with specific fluidic behavior due to micro- and/or nanostructures on the surfaces. With a combination of hot embossing and microthermoforming it is possible to produce microchannels with specific surface properties. These surface properties are highly dependent on the micro- and nanostructures embossed into the material. Different structure sizes and geometries where examined by contact angle measurements. Here the dependency of diameter and pitch of the structures on the contact angle is examined as well as the material impact. These results enable the fabrication of highly specific surfaces tunable to an application.
Glycoprotein B genotype correlates with cell tropism in vivo of human cytomegalovirus infection

Human cytomegalovirus (HCMV) strains can be classified into four genotypes of the glycoprotein B (gB). In a previous study, the gB genotype 1 was found more frequently in bone marrow transplant recipients with nonfatal HCMV infection than in patients who died from HCMV disease [Fries et al. (1994): Journal of Infectious Diseases 169:769–774]. The distribution and cell tropism of different gB types in vivo were investigated. The gB type of HCMV was determined in blood or urine specimen from 76 organ and 47 bone marrow transplant recipients using PCR and restriction fragment length polymorphism (RFLP). The leukocyte populations (polymorphonuclear leukocytes, monocytes, T lymphocytes, non‐T lymphocytes) of 20 viremic patients were purified by a fluorescence‐activated cell sorter (FACS) and examined for HCMV infection by PCR. Sequence analysis of four randomly selected strains showed that gB types were similar to published sequences and no atypical gB types were found. Within the compartments blood and urine, the gB types were almost equally distributed, whereas the gB type 1, in contrast to gB types 2 and 3, did not infect T lymphocytes in vivo. These data show that the gB type correlates with viral tropism in vivo and thus provides further evidence that the gB variation may indeed influence the virulence of HCMV. J. Med. Virol. 54:75–81, 1998. © 1998 Wiley‐Liss, Inc.
Genomic Organization and Localization of Mouse Nma/BAMBI: Possible Implications Related to Ameloblastoma Formation

Our laboratory has determined the DNA sequence and transcriptional expression pattern of a mouse cDNA clone termed Nma/BAMBI. This clone encodes a highly conserved protein with 89% identity to the human homologue (termed Nma) and 78% similarity to the Xenopus homologue (termed BAMBI) at the predicted amino acid level. Nma/BAMBI encodes a 260-amino-acid transmembrane protein that has homology to the transforming growth factor (TGF) g type I receptor family. This protein contains an extracellular ligand binding domain, a 24-amino-acid transmembrane domain, and a short intracellular domain that lacks a functional serine/threonine kinase domain. It is believed that Nma/BAMBI is important in the negative regulation of TGF g signal transduction pathways during development and has implications in tumor progression. We have determined the genomic organization of the mouse Nma/BAMBI gene and confirmed the chromosomal mapping to human chromosome 10 and mouse chromosome 2. Furthermore, we report the production and utilization of an anti-peptide antibody in preliminary immunohistochemical analysis of an ameloblastoma.
The St. Lawrence polynya and the Bering shelf circulation : New observations and a model comparison

[1] Using 14 yearlong instrumented moorings deployed south of St. Lawrence Island, along with oceanographic drifters, we investigate the circulation over the central Bering shelf and the role of polynyas in forming and disseminating saline waters over the shelf. We focus also on evaluating the Gawarkiewicz and Chapman (1995) model of eddy production within coastal polynyas. Principal results include the following. (1) The northern central shelf near-surface waters exhibit westward flow, carrying low-salinity waters from the Alaskan coast in fall and early winter, with consequences for water mass formation and biological production. (2) Within the St. Lawrence polynya the freshening effect of winter advection is about half as large as the salting effect of surface brine flux resulting from freezing. (3) Brine production over the Bering shelf occurs primarily offshore, rather than within coastal polynyas, even though ice production per unit area is much larger within the polynyas. (4) We find little evidence for the geostrophic flow adjustment predicted by recent polynya models. (5) In contrast to the theoretical prediction that dense water from the polynya is carried offshore by eddies, we find negligible cross-shelf eddy density fluxes within and surrounding the polynya and very low levels of eddy energy that decreased from fall to winter, even though dense water accumulated within the polynya and large cross-shore density gradients developed. (6) It is possible that dense polynya water was advected downstream of our array before appreciable eddy fluxes materialized.
RTP Payload Format for the Extended Adaptive Multi-Rate Wideband (AMR-WB+) Audio Codec

This document specifies a real-time transport protocol (RTP) payload format to be used for Extended AMR Wideband (AMR-WB+) encoded audio signals. The AMR-WB+ codec is an audio extension of the AMR-WB codec providing additional frame types designed to give higher quality of music and speech than the original frame types. A media type registration is included for AMR-WB+.
If You Go Down to the Woods Today: Infants’ Distress During a Teddy Bear's Picnic in Relation to Peer Relations and Later Emotional Problems

Infants’ emotional reactions to an unusual event were assessed at a simulated birthday party during which two costumed characters enacted a Teddy Bear's Picnic. Two hundred and fifty‐eight firstborn infants in a representative British community sample were observed at a mean age of 12.8 months in the presence of their parents and other participating families, in a laboratory sitting room decorated with balloons and banners. The picnic scenario was followed by free play with the other participating infants. At a mean of 36 months of age, mothers, fathers, and another informant who knew the child well completed the Child Behaviour Check List (CBCL). The majority of infants showed no vocal distress during the picnic scenario. A minority of infants expressed strong distress, which was correlated with elevated heart rate and production of cortisol. Infants who were not distressed were more likely to direct social behavior to their peers and especially likely to use physical force against peers. In comparison with strongly distressed and nondistressed infants, those who had shown mild distress during the picnic scenario were least likely to manifest later emotional problems. This pattern was particularly marked for boys. Taken together, the findings indicate that infants’ strong distress during naturalistic encounters that are meant to be entertaining can suppress sociability and might indicate risk for subsequent emotional problems.