Miracle-dz/UniFAR-FTUs huggingface dataset:
Evaluation of the Effects of Khaya Gum on the Mechanical and Release Properties of Paracetamol Tablets

Abstract A study of the comparative effects of khaya gum and two standard binding agents––polyvinylpyrrolidone (PVP) and gelatin––on crushing strength and friability, and the disintegration and dissolution characteristics of paracetamol tablets was made. The crushing strength-friability ratio (CSFR), the disintegration times, D, and the dissolution times t50, t90, and t1 (derived from the equation of Noyes and Whitney), all increased with an increase in binder concentration; however, the dissolution rate constants, k1 and k2, decreased. The ranking for the values of CSFR for tablets containing the different binders was PVP>gelatin>khaya gum. The ranking for D and the dissolution times was gelatin>khaya gum>PVP, whereas the ranking for the dissolution rate constants was PVP>khaya gum>gelatin. There were significant linear correlations between CSFR, D, t50, t90, and t1 for the tablets. There were also significant correlations between k1 and D, t50, t90, and t1, and between k2 and t90. The results suggest that khaya gum could be useful as an alternative binding agent to produce tablets with particular mechanical strength and drug release profiles.
Design and analysis of thermoelectric material based roof top energy harvesting system for Pakistan

Main concern of today's era is green energy. Different methods of energy harvesting are introduced, which are free and environmental friendly. Thermoelectric material produces electric potential when temperature difference provide to its end. Pakistan has a solar irradiance of 2400 kWh/m2 per year and temperature will rise up to 45° to 50° in many cities during summer. Use of air conditioner is now very common. Research analyzes energy extraction due to that temperature change from thermoelectric material based roof top in summer. Total average power generated through this method is studied. Research also determines the design and implementation of energy harvesting roof top.
Strategic Pricing of New Products and Services

This chapter organizes and reviews the literature on new product pricing, with a primary focus on normative models that take a dynamic perspective. Such a perspective is essential in the new product context, given the underlying demandand supply-side dynamics and the need to take a long-term, strategic, view in setting pricing policy. Along with these dynamics, the high levels of uncertainty (for fi rms and customers alike) make the strategic new product pricing decision particularly complex and challenging. Our review of normative models yields key implications that provide (i) theoretical insights into the drivers of dynamic pricing policy for new products and services, and (ii) directional guidance for new product pricing decisions in practice. However, as abstractions of reality, these normative models are limited as practical tools for new product pricing. On the other hand, the new product pricing tools available are primarily helpful for setting specifi c (myopic) prices rather than a dynamic long-term pricing policy. Our review and discussion suggest several areas that offer opportunities for future research.
Local hematopoietic renin-angiotensin system in myeloid versus lymphoid hematological neoplastic disorders

There is preliminary evidence that the local renin-angiotensin system (RAS) could affect neoplastic hematopoiesis. The aim of this study is to search messenger RNA (mRNA) expressions of the essential RAS elements in myeloid and lymphoid hematological neoplastic disorders. Forty-six patients with newly diagnosed myeloid (AML, biphenotypic leukemia, CML) or lymphoid (CLL, NHL, B-ALL, T-ALL) hematological disorders were included in the study. In the lymphoid group, the median expression values of RENIN, ACE1, ACE2 and ANGIOTENSINOGEN (ANGTS) mRNAs were 1.96%, 0.42%, 0.00% and 0.00%, respectively; in the myeloid group, 0.73%, 1.55%, 0.04% and 0.006%, respectively. In the lymphoid group, RENIN levels were significantly higher (p = 0.001), whereas ACE1 and ACE2 levels were significantly higher in the myeloid group (p values were 0.013 and 0.010, respectively). ANGTS levels were similar in both groups. In patients with non-ALL lymphoid malignancies, RENIN expressions were significantly higher when compared to ALL patients (p = 0.004). All patients with active disease had significantly higher RENIN mRNA expression levels than patients without active disease (2.03% vs 0.30%) (p = 0.034). The result of our present study indicates that the activities of local RAS may differ in distinct disease states such as leukemia and lymphomas.
Towards Analyzing Adversarial Behavior in Clandestine Networks

Adversarial behavioral has been observed in many different contexts. In this paper we address the problem of adversarial behavior in the context of clandestine networks. We use data from a massively multiplayer online role playing game to illustrate the behavioral and structural signatures of deviant players change over time as a response to "policing" activities of the game administrators. Preliminary results show that the behavior of the deviant players and their affiliates show co-evolutionary behavior and the timespan within the game can be divided into different epochs based on their behaviors. Feature sets derived from these results can be used for better predictive machine learning models for detecting deviants in clandestine networks.
Quagmire: Revision of a Classic Recreation Resource Management Simulation Game

Simulation games have been used as an education tool in many fields. From flight simulators to the Model UN, simulations can engage students and increase their learning. Before students became proficient in using the Internet, the Quagmire simulation game, developed by Dan Dustin, was often used to illustrate the complexity of public land management in the United States. Students' increasing Internet proficiency led to frustration as they tried to research management alternatives to a fictional site. Modifying Dustin's Quagmire resulted in the development of an Internet compatible version of the simulation. This simulation is interwoven with class lectures to reinforce key content of a recreation resource management course throughout the semester.
The Prevention and Management of Distant Metastases in Women with Breast Cancer

About one-third of all women diagnosed with breast cancer face the risk of recurrence, which can occur at any stage of disease, observation time, and after any treatment modality. Most recurrence comes in the form of distant metastasis, which is the major cause of death in women with breast cancer. Treatments shown to decrease the risk of breast cancer recurrence, especially distant metastasis, will likely produce a survival benefit and a potentially significant improvement in quality of life in women with early breast cancer. New third-generation aromatase inhibitors (anastrozole, exemestane, and letrozole) that have been shown to be well tolerated have the potential to contribute to benefits beyond those seen with tamoxifen.
Import of cytochrome b2 to the mitochondrial intermembrane space: The tightly folded heme‐binding domain makes import dependent upon matrix ATP

Cytochrome b2 is synthesized as a precursor in the cytoplasm and imported to the intermembrane space of yeast mitochondria. We show here that the precursor contains a tightly folded heme‐binding domain and that translocation of this domain across the outer membrane requires ATP. Surprisingly, it is ATP in the mitochondrial matrix rather than external ATP that drives import of the heme‐binding domain. When the folded structure of the heme‐binding domain is disrupted by mutation or by urea denaturation, import and correct processing take place in ATP‐depleted mitochondria. These results indicate that (1) cytochrome b2 reaches the intermembrane space without completely crossing the inner membrane, and (2) some precursors fold outside the mitochondria but remain translocation‐competent, and import of these precursors in vitro does not require ATP‐dependent cytosolic chaperone proteins.
Environmental Protection Expenditures and Effects of Environmental Governance of Sustainable Development in Manufacture Enterprise

The article concentrates on the effects of the environmental governance of sustainable development. It examines the relationship between environmental protection expenditures and the effects of the environmental governance of sustainable development. In order to reduce the variables determining the number of effects the Principal Component Analysis was used. Analyses are related to the European Union countries and cover the 2008-2014 period. The research is based on the industry sector. Over the whole analysed period the positive trends in the effects of the environmental governance of sustainable development were observed in the majority of the analysed countries. The results of the analysis show that an increase in environmental protection expenditure is not always followed by an increase in ecological effects.
Supply chain risk assessment: a content analysis-based literature review

In recent years, along with globalisation trend, risk management has been an integral part in supply chain management. In this vein, supply chain risk assessment has become an active and important research subject. There is considerable research and debate on the approach and method of assessing risk in order to obtain a sound base for decision making in supply chain and supply chain risk management. This paper aims to synthesise overall aspects of supply chain risk assessment in the literature. To this end, we have investigated 140 peer-reviewed articles in high quality journals by using a content analysis method and a systematic approach. The heterogeneous definitions, focuses, procedures, methods, and indicators of supply chain risk assessment referred to in previous research are comprehensively analysed and presented in classification frameworks in order to gain insights into this field, explore research gaps, and provide an outlook for future research.
The Movement and Change in Online Price Within and Across Selected Major Retail Stores in Thailand

E-commerce has gained larger market shares in Thailand over the last decade. Yet there is a paucity of studies on online price behaviour and movement. This project is one of the first attempts to explore this topic in the Thai context. Using web scraping technique to acquire the data on price and product information from major retailers that have both physical and online outlets, this paper summarizes its findings into six stylized facts. In short, online price changes more frequent than its offline counterpart, yet the magnitudes of changes are generally much larger. Further, price heterogeneity exists across stores and product categories. However, pricing strategies of the same store seems to differ between its online and offline outlets.
A Reactive Approach for Use-Based Privacy

Use-based privacy, which equates privacy with preventing harmful uses of sensitive information, has been proposed as a means to enhance privacy in networked information systems. This work explores the feasibility of expressing and enforcing use-based privacy. The first step of this exploration is to identify patterns in which uses are considered harmful; a survey of privacy regulations and a user study both suggest that a reactive policy language—one that specifies not only a current set of use restrictions but also describes how those use restrictions change after a sequence of events occurs—might be well-suited to use-based privacy. Avenance, a reactive policy specification language for use-based privacy, is described, and its expressiveness is evaluated. A mechanism is also described for facilitating Avenance policy enforcement, where policy is separated from code and an inline monitor performs automated compliance checking. This work can be viewed as positive evidence of the feasibility use-based privacy.
Why do consumers of organic food have more nutritionally balanced diets? – a Danish study

Policies encouraging consumers to follow nutritional dietary guidelines are widely used by governments as a strategy to improve public health. Organic consumers seem to adhere to nutritional guidelines more than others, but it remains obscure why, exactly, there is a correlation between eating healthily and organic consumption. Based on six focus groups, 1519 survey respondents, and purchase data from 2449 households (all data collected in Denmark), we found that not only dedicated but also occasional organic consumers eat more fruit and vegetables and less meat than consumers with no or little organic consumption. We also found that earlier findings on product-level consumption carried over to a meal context, where organic consumers were more likely to substitute some of the meat in their meal with vegetables than non-organic consumers. When respondents were asked about healthy food in general, nutritional health (involving fat, sugar, nutrients) was the dominant health dimension, but the health benefits of organic food were linked to the purity of organic products (e.g. being free-from pesticides, drug residues and artificial additives). We conclude that organic consumption and a nutritionally balanced diet are both driven by an underlying interest in health.
Mécanismes de retransmission Hybrid-ARQ en radio-cognitive.

Dans les standards actuels tels que HSDPA ou LTE, des protocoles de retransmissions (ARQ: Automatic Repeat reQuest) sont utilises conjointement au codage de canal afin de palier aux erreurs dues a l'absence ou la mauvaise de connaissance de canal a la transmission. On garantit ainsi la fiabilite du lien physique pour les couches OSI superieures (du moins un taux d'erreur paquet faible). De tels protocoles sont appeles protocoles de retransmission hybrides (HARQ). L'objet de cette these est de proposer des outils permettant l'analyse et l'optimisation des systemes de communication en presences de protocoles HARQ avec une emphase particuliere sur les systemes cognitifs.Dans la premiere partie, nous etudierons un systeme point-a-point dans lequel trois differents protocoles HARQ adaptatifs seront consideres. Dans un premier temps, nous considererons le regime asymptotique (i.e. codes optimaux gaussiens). Nous proposerons, dans ce cas, deux optimisations possibles : la minimisation de la puissance moyenne sous la contrainte de debit moyen et la maximisation du debit moyen sous une contrainte de puissance moyenne. Nous montrerons que les Processus de Decision Markoviens (MDP) sont des outils adaptes aux problemes d'optimisation consideres.Dans les standards actuels tels que HSDPA ou LTE, des protocoles de retransmissions (ARQ: Automatic Repeat reQuest) sont utilises conjointement au codage de canal afin de palier aux erreurs dues a l'absence ou la mauvaise de connaissance de canal a la transmission. On garantit ainsi la fiabilite du lien physique pour les couches OSI superieures (du moins un taux d'erreur paquet faible). De tels protocoles sont appeles protocoles de retransmission hybrides (HARQ). L'objectif de cette these est de proposer des outils permettant l'analyse et l'optimisation des systemes de communication en presences de protocoles HARQ avec une emphase particuliere sur les systemes cognitifs. La radio cognitive est une approche permettant a des utilisateurs non-licencies de communiquer dans les memes bandes de frequences que des utilisateurs licencies afin d'augmenter l'efficacite spectrale des reseaux sans fil. Les utilisateurs secondaires doivent neanmoins limiter les interferences generees sur les signaux des utilisateurs primaires. Dans ce contexte, nous etudierons les debits atteignables par un utilisateur secondaire utilisant l'observation du protocole HARQ de l'utilisateur primaire afin de controler son interference.
Timing of antibiotic prophylaxis for primary total knee arthroplasty performed during ischemia.

BACKGROUND There is no clinical trial analyzing the best moment to infuse an antibiotic during knee arthroplasty performed during ischemia. We designed a single-center, randomized, double-blind, placebo-controlled trial to evaluate whether antibiotic therapy should be administered before tourniquet inflation or just before tourniquet deflation. MATERIAL AND METHODS Patients who underwent a primary knee arthroplasty were randomized to receive (1) 1.5 g of cefuroxime 10-30 min before inflation of the tourniquet and placebo 10 min before release of the tourniquet (standard arm) or (2) placebo 10-30 min before inflation of the tourniquet and 1.5 g of cefuroxime 10 min before release of the tourniquet (experimental arm). In both arms, a postoperative dose of 1.5 g of cefuroxime was given 6 h after the surgical procedure. The main variables associated with the rate of deep-tissue infection after 3 and 12 months of follow-up were gathered. Continuous variables were compared using Student's t test, and categorical variables were compared using the chi(2) test or Fisher's exact test. RESULTS From September 2004 through December 2005, a total of 908 patients were randomized, 442 and 466 of whom were allocated to the standard and experimental arms, respectively. There were no differences between treatment arms in terms of age, sex, comorbidity, American Society of Anaesthesiologists score, duration of surgery, need of blood transfusion, or fourth-day hematocrit. The rates of deep-tissue infection among the standard and experimental groups were 3.4% and 1.9%, respectively, at 3 months of follow-up (P = .21) and 3.6% and 2.6%, respectively, at 12 months of follow-up (P = .44). CONCLUSION The administration of prophylactic antibiotics just before tourniquet release was not inferior to standard antibiotic prophylaxis.
Maximum Storm Tide Response to the Intensity of Typhoons and Bathymetric Changes along the East Coast of Taiwan

A typhoon-induced storm surge is considered one of the most severe coastal disasters in Taiwan. However, the combination of the storm surge and the astronomical tide called the storm tide can actually cause extreme flooding in coastal areas. This study implemented a two-dimensional hydrodynamic model to account for the interaction between tides and storm surges on the coast of Taiwan. The model was validated with observed water levels at Sauo Fish Port, Hualien Port, and Chenggong Fish Port under different historical typhoon events. The model results are in reasonable agreement with the measured data. The validated model was then used to evaluate the effects of the typhoon's intensity, bathymetric change, and the combination of the typhoon’s intensity and bathymetric change on the maximum storm tide and its distribution along the east coast of Taiwan. The results indicated that the maximum storm tide rises to 1.92 m under a typhoon with an intensity of a 100-year return period. The maximum storm tide increased from a baseline of 1.26 m to 2.63 m for a 90% bathymetric rise at Sauo Fish Port under the conditions of Typhoon Jangmi (2008). The combination of the intensity of a typhoon with a 100-year return period and a 90% bathymetric rise will result in a maximum storm tide exceeding 4 m, 2 m, and 3 m at Sauo Fish Port, Hualien Port, and Chenggong Fish Port, respectively. We also found that the distribution of the maximum storm tide on the east coast of Taiwan can expand significantly subject to the bathymetric rise.
A modified orthogonal matching algorithm using correlation coefficient for compressed sensing

This paper presents a modified orthogonal matching pursuit (OMP) algorithm for compressed sensing (CS). Compared with the standard OMP algorithm, the most innovation of this algorithm is its improvement on the reconstruction probability of the sparse signal, and the basic idea is that the support set is estimated using correlation coefficient because the correlation coefficient can be viewed as a normalized matching criterion. In the standard OMP algorithm, the inner product is used for estimating the support set of the sparse signal, which may generate the wrong coordinates because the inner product couldn't guarantee the expected column of sensing matrix matches the measurement vector very best. However, the proposed algorithm is able to demonstrate a better performance on estimating the support set to some extent. From the simulation results, the proposed algorithm outperforms the standard OMP algorithm.
Use of advanced features and perceptions of software quality: an experimental study

An experiment was conducted to investigate the impacts of use of advanced features on perceptions of software quality. Subjects were given the task of planning an information systems development project. They were provided with project management software and given an opportunity to use advanced features. Two levels of task difficulty (high and low), and two levels of performance feedback (positive feedback and no feedback) were manipulated. Results show that when the more advanced features are used, more computing problems and less positive attitudes toward the software are reported. However, the contextual variables show moderating effects on this relationship. Under the condition of either low task difficulty or no performance feedback, the negative relationship between extensiveness of use and attitudes toward the software is statistically significant. <<ETX>>
Proposition de l'architecture "Cortexionist" pour l'intelligence comportementale de créatures artificielles

Traditionnellement, la production de comportements intelligents pour les creatures artificielles repose sur la modelisation de leurs facultes cognitives. Cette approche pose deux problemes essentiels. D'une part, la lourde charge de definir manuellement les connaissances d'un agent necessite l'intervention d'un animateur, d'autre part la relation cognition-->intelligence n'a jamais ete averee theoriquement ni experimentalement. C'est face a ces deux defis que les approches ecologiques apparaissent comme de nouvelles pistes explorant les liens entre la creature, son corps et son environnement. Ce travail de recherche s'inscrit dans cette optique. Partant de la synthese de theories provenant de diverses disciplines des neurosciences, nous proposons, dans une approche vie artificielle, une modelisation originale de la memoire. Le controleur Cortexionist est une architecture reactive connexionniste qui integre une memoire associative favorisant l'adaptation de l'agent dans un environnement dynamique. L'obtention de regles comportementales emergentes lors des experimentations revele la relation qu'entretiennent la complexite de l'environnement et celle du comportement des creatures qui y evoluent.
Creation and Regulation of Bank Liquidity

Liquidity creation is a core function of banks and an important economic service to the economy. This chapter discusses two distinct notions of bank liquidity creation developed in the theoretical literature—funding liquidity creation and improved risk sharing for risk-averse depositors. It also examines the empirical literature on bank liquidity creation. The focus is on the economics of bank liquidity creation, both in the traditional relationship banking context and in the shadow-banking context. This chapter discusses related prudential regulation issues, pertaining mainly to capital requirements and liquidity requirements, as well. It provides a historical overview, starting in the early 1800s and ending with Basel III and the Dodd–Frank Act. It identifies open research questions regarding both capital requirements and liquidity requirements.