Miracle-dz/UniFAR-FTUs huggingface dataset:
Prediction of Reading Disabilities in Kindergarten and First Grade

The goal of this study was to design a small set of phonological, letter, and memory tasks that would reliably identify children likely to develop reading disabilities (RD). We tested children in kindergarten and followed them through 1st grade, layering the investigation by testing various cohorts from diverse geographic, community, and economic conditions. Our strategy involved establishing selection measures and criteria by calibrating indicators of RD on 1 cohort of children, testing the parameters on a new cohort, exploring the relative accuracy of predictors gathered over time, and testing the contribution of dynamic segmentation in which children received varying levels of prompts in performing the task. Discriminant analysis based on a small set of predictors yielded high hit rates in distinguishing children who exhibited an RD profile at the end of 1st grade. Measures taken early in 1st grade were more accurate discriminators than were measures taken late in kindergarten, which were more discrimi.
Expression of hepatic transcription factors during liver development and oval cell differentiation

The oval cells are thought to be the progeny of a liver stem cell compartment and strong evidence now exists indicating that these cells can participate in liver regeneration by differentiating into different hepatic lineages. To better understand the regulation of this process we have studied the expression of liver-enriched transcriptional factors (HNF1 alpha and HNF1 beta, HNF3 alpha, HNF3 beta, and HNF3 gamma, HNF4, C/EBP, C/EBP beta, and DBP) in an experimental model of oval cell proliferation and differentiation and compared the expression of these factors to that observed during late stages of hepatic ontogenesis. The steady-state mRNA levels of four (HNF1 alpha, HNF3 alpha, HNF4, and C/EBP beta) "liver-enriched" transcriptional factors gradually decrease during the late period of embryonic liver development while three factors (HNF1 beta, HNF3 beta, and DBP) increase. In the normal adult rat liver the expression of all the transcription factors are restricted to the hepatocytes. However, during early stages of oval cell proliferation both small and large bile ducts start to express HNF1 alpha and HNF1 beta, HNF3 gamma, C/EBP, and DBP but not HNF4. At the later stages all of these factors are also highly expressed in the proliferating oval cells. Expression of HNF4 is first observed when the oval cells differentiate morphologically and functionally into hepatocytes and form basophilic foci. At that time the expression of some of the other factors is also further increased. Based on these data we suggest that the upregulation of the "establishment" factors (HNF1 and -3) may be an important step in oval cell activation. The high levels of these factors in the oval cells and embryonic hepatoblasts further substantiates the similarity between the two cell compartments. Furthermore, the data suggest that HNF4 may be responsible for the final commitment of a small portion of the oval cells to differentiate into hepatocytes which form the basophilic foci and eventually regenerate the liver parenchyma.
Conformity to feminine gender norms in the Spanish population

In this study, the aim was to describe the adaptation of the Conformity to Feminine Norms Inventory (CFNI; Mahalik et al., 2005) for the Spanish population. The CFNI is used to assess women’s conformity to feminine norms in the United States of America, from a multidimensional perspective. The protocol of the International Test Commission was followed when adapting the inventory. The questionnaire was administered to 780 Spanish women between 18 and 59 years of age. Factor analysis revealed a similar profile to that obtained in the USA and, although it is different in some aspects, it supports the structure proposed by the authors. The reliability data (alpha coefficient of the total scale of .87) also confirm the validity of the CFNI for use in the Spanish population.
Apoptosis is not involved in the mechanism of myocardial dysfunction after resuscitation in a rat model of cardiac arrest and cardiopulmonary resuscitation

Objective:To investigate the presence of apoptosis after the global myocardial ischemia of cardiopulmonary resuscitation and the regional myocardial ischemia after left anterior descending coronary artery occlusion and relate it to the severity of postresuscitation myocardial dysfunction. Design:Prospective animal study. Setting:University-affiliated animal research laboratory. Subjects:Male Sprague-Dawley rats. Interventions:Fifteen male Sprague-Dawley rats weighing 450–550 g were randomized to: (1) 8 mins of untreated cardiac arrest followed by 6 mins of cardiopulmonary resuscitation; (2) left anterior descending coronary artery occlusion for 45 mins followed by 4 hrs of reperfusion; and (3) left anterior descending coronary artery sham group. Cardiac functions, including ejection fraction, analog differentiation of left ventricular pressure at 40 mm Hg, and rate of maximal left ventricular pressure decline were continuously measured for 4 hrs. The hearts were then harvested for the terminal transferase-mediated 2′-deoxyuridine, 5′-triphosphate nick end-labeling assay analysis. Measurements and Main Results:Myocardial function was significantly impaired after resuscitation from cardiac arrest and reperfusion from left anterior descending coronary artery occlusion (p < .01). There was no difference in the percentage of apoptotic cells between the cardiopulmonary resuscitation animals and sham-operated animals. Fewer apoptotic cells were observed in cardiac arrest/cardiopulmonary resuscitation animals in comparison to left anterior descending coronary artery occlusion animals (p < .05), even though myocardial function was more severely impaired after resuscitation (p < .01). Conclusions:Myocardial function was significantly impaired after cardiac arrest/cardiopulmonary resuscitation and ischemia/reperfusion. However, apoptosis was not involved in the mechanism of postresuscitation myocardial dysfunction in this setting.
SAT-Controlled redundancy addition and removal — a novel circuit restructuring technique

We proposed a novel Boolean Satisfiability (SAT)-controlled redundancy addition and removal (RAR) algorithm to resolve the performance and quality problems of the previous RAR approaches. With the introduction of modern SAT techniques, such as efficient Boolean constraint propagation (BCP), conflict-driven learning, and flexible decision procedure, our RAR engine can identify 10x more alternative wires/gates while achieving 70% reduction in runtime.
Generalized constraints for NMF with application to informed source separation

Nonnegative matrix factorization (NMF) is a widely used method for audio source separation. Additional constraints supporting e.g. temporal continuity or sparseness adapt NMF to the structure of audio signals even further. In this paper, we propose generalized NMF constraints which make use of prior information gathered for each component individually. In general, this information could be obtained blindly or by a training step. Here we make use of these novel constraints in an algorithm for informed audio source separation (ISS). ISS uses source separation to code audio objects by assisting a source separation step in the decoder with parameters extracted with knowledge of the sources in the encoder. In [1], a novel algorithm for ISS was proposed which makes use of an NMF step in the decoder. We show in experiments that the generalized constraints enhance the separation quality while keeping the additionally needed bit rate very low.
Substantial Fault Pair At-a-Time (SFPAT): An Automatic Diagnostic Pattern Generation Method

Volume diagnosis plays an important role in the yield learning process. To get a high quality diagnosis result, patterns with high distinguish ability are essential. However, the test patterns used by volume diagnosis commonly have low distinguish ability to specific faults. In our experiments, we observe that on average, under automatic generated test patterns, faults in the same fan out free region (FFR) account for only 6% of all possible fault pairs, but their share in total indistinguishable faults is 70%, faults in different FFRs but with the same observation points account for 4% of all fault pairs, but their share in total indistinguishable faults is 22%. Exploiting this fact that faults in the same FFRs are harder to be distinguished, we propose an Automatic Diagnostic Pattern Generation (ADPG) method named Substantial Fault Pairs at-A-Time (SFPAT)-ADPG. By applying a transformed circuit and a new fault list to an existing Automatic Test Pattern Generation (ATPG) tool, we generate the compressed test patterns which are also the diagnostic patterns with high distinguish ability for the original circuit. Experiments on ISCAS'89 and ITC'99 benchmark circuits show the effectiveness of the proposed SFPAT-ADPG method.
The Impact of Anisotropy on the Accuracy of Conductivity Imaging: A Quantitative Validation Study

We present a quantitative validation study to assess the accuracy of low-frequency conductivity imaging methods, based on a testing current measured using Current Density Imaging (CDI). We tested the proposed procedure to study the influence of tissue anisotropy on the accuracy of conductivity reconstruction methods, using a finite element model of anisotropic brain tissue. Simulations were carried out for three different levels of tissue anisotropy to compare the results obtained by our recently developed anisotropic conductivity method with those obtained by our well-established conductivity method that assumes isotropic conductivity. The validation results clearly show that the conductivity imaging method which takes into account tissue anisotropy yields significantly superior accuracy.
F-Like Type IV Secretion Systems Encode Proteins with Thioredoxin Folds That Are Putative DsbC Homologues

ABSTRACT F and R27 are conjugative plasmids of enteric bacteria belonging to the IncF and IncHI1 plasmid incompatibility groups, respectively. Based on sequence analysis, two genes of the F transfer region, traF and trbB, and three genes of the R27 transfer region, trhF, dsbC, and htdT, are predicted to encode periplasmic proteins containing a C-terminal thioredoxin fold. The C-X-X-C active-site motif of thioredoxins is present in all of these proteins except TraFF. Escherichia coli carrying a dsbA mutation, which is deficient in disulfide bond formation, cannot synthesize pili and exhibits hypersensitivity to dithiothreitol (DTT) as monitored by mating ability. Overproduction of the E. coli disulfide bond isomerase DsbC, TrbBF, DsbCR27, or HtdTR27, but not TraFF or TrhFR27, reverses this hypersensitivity to DTT. Site-directed mutagenesis established that the C-X-X-C motif was necessary for this activity. Secretion into the periplasm of the C-terminal regions of TrbBF and DsbCR27, containing putative thioredoxin folds, but not TrhFR27, partially complemented the host dsbA mutation. A trbBF deletion mutant showed a 10-fold-lower mating efficiency in an E. coli dsbC null strain but had no phenotype in wild-type E. coli, suggesting redundancy in function between TrbBF and E. coli DsbC. Our results indicate that TrbBF, DsbCR27, and HtdTR27 are putative disulfide bond isomerases for their respective transfer systems. TraFF is essential for conjugation but appears to have a function other than disulfide bond chemistry.
Iteratively collective prediction of disease-gene associations through the incomplete network

The prediction of links between genes and disease is still one of the biggest challenges in the field of human health. Almost all state-of-the-art studies on the prediction of gene-disease links focuson a single pair of links, ignoring the associations and interactions among different types of links. Moreover, the biological information networks are usually incomplete. In this paper, we study the similarity measure to be used on two different types of nodes, based on the metapaths between them (Wsrm). Then an iterative self-updating approach for link prediction using heterogeneous information network is proposed to fit the incompletion of the network (ISL), which is a semi-supervised learning formula. Using the biological integrated network constructed from OMIM and HumanNet dataset (30,896 nodes and 1,200,166 edges) we applied our framework. The area under the receiver operating characteristic is 0.941, indicating that our approach significantly outperforms the state-of-the-art gene-disease link prediction approaches. Moreover, the sensitivity analysis signifies that our approach is robust. Consequently, our proposed framework demonstrates an efficient and accurate approach for link prediction between genes and diseases. In addition, during iteration, the accuracy of the result gradually increases. The example dataset and the implementation of our approach is avaliable at https://github.com/xymeng16/ISL.
A Human Family: Commentary on Paper by Elisabeth Fivaz-Depeursinge, Chloé Lavanchy-Scaiola, and Nicolas Favez

In discussing the paradigm shifting work of Fivaz-Depeursinge and her colleagues, I illustrate how developmental conceptions have shifted from a narrative centered on the discovery of “an Other” to narratives emphasizing what these authors term “collective intersubjectivity. ” In this latter view, humans simultaneously share affect and intention with multiple others from birth, and subsequently continue to develop increasingly sophisticated means for doing so thorough out their lives. I situate this phenomenon in philosophy, nonlinear dynamic systems theory and evolutionary biology in order to highlight the species specific, phenomenologically given, and ecologically situated aspects of our intersubjective condition. Intersubjectivity from the perspective of Fivaz-Depeursinge and her group opens us to this collective dimension of membership in a human family.
Modulation Wiener filter for improving speech intelligibility

This paper presents a single-channel high-dimensional Wiener filter in the spectro-temporal modulation domain. Unlike other conventional noise reduction techniques, the proposed algorithm not only reduces noise but also enhances the “textures” of the speech signal. A non-iterative decision-directed noise estimation method is adopted to estimate the modulation SNR for the modulation-domain Wiener filter. The efficacy of the proposed algorithm in enhancing speech intelligibility is assessed using the short-time objective intelligibility (STOI) measure. Statistical analysis results demonstrate that our proposed algorithm can improve STOI scores in speech-shape noise (SSN) and white noise conditions, but not in babble noise condition, while the conventional Wiener filter fails to improve STOI scores in all three noise conditions.
Growth of Au Nanoparticles on 2D Metalloporphyrinic Metal‐Organic Framework Nanosheets Used as Biomimetic Catalysts for Cascade Reactions

Inspired by the multiple functions of natural multienzyme systems, a new kind of hybrid nanosheet is designed and synthesized, i.e., ultrasmall Au nanoparticles (NPs) grown on 2D metalloporphyrinic metal‐organic framework (MOF) nanosheets. Since 2D metalloporphyrinic MOF nanosheets can act as the peroxidase mimics and Au NPs can serve as artificial glucose oxidase, the hybrid nanosheets are used to mimic the natural enzymes and catalyze the cascade reactions. Furthermore, the synthesized hybrid nanosheets are used to detect biomolecules, such as glucose. This study paves a new avenue to design nanomaterial‐based biomimetic catalysts with multiple complex functions.
‘Prove it!’ same-sex performativity among sexual minority women and men

Past research has focused on understanding performances of same-sex sexual behaviour between women as occurring in high-pressure exploitative contexts, primarily for the purpose of arousing a male audience. These women, who are presumed heterosexual, have been described as ‘performing bisexuality’ for an also presumably heterosexual male audience. Drunkenness, dares and fulfilling others’ desires are common reasons why heterosexual individuals perform public same-sex sexual behaviour. The present study explored same-sex performative behaviour among sexual minority individuals. Participants included 84 young adults (age 18–25) who identified as lesbian, gay, bisexual and queer. Participants completed an anonymous online survey consisting of both qualitative and quantitative questions about their same-sex performative behaviour, as well as their attitudes towards such behaviours. Results revealed that sexual minority women are asked more frequently to engage in same-sex performative behaviour than sexual minority men. Findings also showed that sexual minority participants are expected to engage in performative same-sex sexual behaviours to authenticate their sexual orientation label. Discussion focuses on the unique perspective of sexual minorities regarding same-sex performance and also explores potential sex differences in the findings.
Managing media relations in museums through the Internet: a model of analysis for online pressrooms in museums

The main objective of this article is to analyze online pressrooms developed by museums on their corporate websites, and to assess how these institutions communicate with the media. Four key elements are evaluated: the presence of online pressrooms on museum websites, the type of content given, the information tools provided, and the resources available for providing feedback. The results suggest that the museums studied do not use the advantages of online pressrooms to communicate more frequently and better with journalists and, instead, merely reproduce the one-way, passive forms of traditional offline media relations. The paper helps to define a model for analyzing online pressrooms that shows how museums develop their media relations through the Internet and how they can implement tools to foster and improve interactive communication with the mass media.
Collateral report of psychopathy: convergent and divergent validity of the psychopathic personality inventory-short form

Psychopathy is a personality syndrome comprised of interpersonal, affective, and behavioral features that has emerged as a correlate of intimate partner violence perpetration. One commonly used self-report measure of psychopathy is the Psychopathic Personality Inventory-Short Form (PPI-SF). The current study employed a multi-trait, multi-method approach to test convergent and discriminant validity of the measure in partner-violent couples by comparing males’ self-report of psychopathy to the informant report of their female partner (N = 114). It was hypothesized that the female partner report of the male’s psychopathy would be highly correlated with the male report of his own psychopathy, thus providing evidence for the construct validity and interrater reliability of the PPI-SF. Analyses found that male and female reports were correlated significantly on the two major factors of the PPI-SF. Furthermore, the female report explained a significant amount of variance over and above men’s self-report on PAI scales designed to indicate antisocial personality traits.
Older people”s performance on the profile of mood states (Poms)

This paper reports on the psychometric properties and feasibility of using the Profile of Mood State (POMS) with older adults to establish its cross-age usefulness in assessing emotional states. The POMS Scale, along with measures of functional status and Bradburn's Affect Balance Scale, was administered to 505 older adults 65 and over recruited from 4 different locations. Exploratory factor analysis indicated a similar factor structure for both the older adult and the original standardized samples for five of the six original factors (Tension, Depression, Anger, Fatigue and Vigor). There were enough differences between the sixth original factor (Confusion) and older-persons confusion factor to warrant a different scoring for older samples. Tests of validity demonstrated concurrent relationships of the POMS scores with indicators of competence and psychological well-being. Cross-sectional age comparisons on the POMS factors inidcated that older subjects appeared relatively healthier than the original samp.
Photosensitized inactivation of microorganisms

Despite major advances in medicine in the last 100 years, microbiologically-based diseases continue to present enormous global health problems. New approaches that are effective, affordable and widely applicable and that are not susceptible to resistance are urgently needed. The photodynamic approach is known to meet at least some of these criteria and, with the creation and testing of new photosensitisers, may develop to meet all of them. The approach, involving the combination of light and a photosensitising drug, is currently being applied to the treatment of diseases caused by bacteria, yeasts, viruses and parasites, as well as to sterilisation of blood and other products.
Democracy and Confucian Values

This essay considers a number of proposals for liberal political democracy in East Asian societies, and some of the critical responses such proposals have attracted from political philosophers and from East Asian intellectuals and leaders. These proposals may well be ill-suited to the distinctive traditional values of societies claiming a Confucian inheritance. Offered here instead is a pragmatist- and Confucian-inspired vision of participatory democracy in civic life that is possibly better able to address the problem of conserving and continuing these traditional values through times of economic and social change.
A mudança no modelo de ensino e de formação na engenharia

The accelerated development of the industry not only make that the professional market demands more and more from the workers qualification and efficiency, but it requests a retaking of the relationships among that scenery and the one that it is put as teaching model and of the engineers' formation. It is, then, the discussion on how the changings presented by the society have been contemplating in the process of the engineering professional's formation, and vice versa. The purpose of this article is to present an abbreviation analysis of as the change of the professional market it is influencing the engineers' formation. The teaching in the engineerings is still distant of an appropriate model. In order to an improvement, it is necessary a changing in the model of traditional teaching, based in the professionals' experiences. It is not possible to suppose immediately that those measured and the absorption of the competence notion for the education institutions is simply a reflex of the world of working. The incorporation of the changes is slow and it depends on factors that goes beyond the extent of the school. They are in the dependence of the public politics that guide the teachers' formation and of the resources related to the institutions that will to turn operating.
SENDIM for Incremental Development of Cloud Networks

Due to the limited and varying availability of cheap infrastructure and resources, cloud network systems and applications are tested in simulation and emulation environments prior to physical deployments, at different stages of development. Configuration management tools manage deployments and migrations across different cloud platforms, mitigating tedious system administration efforts. However, currently a cloud networking simulation cannot be migrated as an emulation, or vice versa, without rewriting and manually re-deploying the simulated application. This paper presents SENDIM (Sendim is a northeastern Portuguese town close to the Spanish border, where the rare Mirandese language is spoken), a Simulation, Emulation, aNd Deployment Integration Middleware for cloud networks. As an orchestration platform for incrementally building Software-Defined Cloud Networks (SDCN), SENDIM manages the development and deployment of algorithms and architectures the entire length from visualization, simulation, emulation, to physical deployments. Hence, SENDIM optimizes the evaluation of cloud networks.