Miracle-dz/UniFAR-FTUs huggingface dataset:
Bridging the User Intention Gap: an Intelligent and Interactive Multidimensional Music Search Engine

Music is inherently abstract and multidimensional. However, existing music search engines are usually not convenient or too complicated for users to create multidimensional music queries, leading to the intention gap between users' music information needs and the input queries. In this paper, we present a novel content-based music search engine, the Intelligent & Interactive Multidimensional mUsic Search Engine (i2MUSE), which enables users to input music queries with multiple dimensions efficiently and effectively. Six musical dimensions, including tempo, beat strength, genre, mood, instrument, and vocal, are explored in this study. Users can begin a query from any dimension and interact with the system to organize the query. Once the parameters of some dimensions have been set, i2MUSE is able to intelligently highlight a suggested parameter and gray out an un-suggested parameter for every other dimension, helping users express their music intentions and avoid parameter conflicts in the query. In addition, i2MUSE provides a real-time illustration of the percentage of matched tracks in the database. Users can also set the relative weight of each specified dimension. We have conducted a pilot user study with 30 subjects and validated the effectiveness and usability of i2MUSE.
T‐antigen of the human polyomavirus JC attenuates faithful DNA repair by forcing nuclear interaction between IRS‐1 and Rad51

JC polyomavirus (JCV), which infects 90% of the human population, is detectable in human tumors. Its early protein, JCV T‐antigen, transforms cells in vitro and is tumorigenic in experimental animals. Although T‐antigen‐mediated transformation involves genetic alterations of the affected cells, the mechanism underlying this genomic instability is not known. We show that JCV T‐antigen inhibits homologous recombination DNA repair (HRR), which results in an accumulation of mutations. T‐antigen does not operate directly but utilizes a cytosolic molecule, insulin receptor substrate 1 (IRS‐1). Following T‐antigen‐mediated nuclear translocation, IRS‐1 binds Rad51 at the site of damaged DNA. This T‐antigen‐mediated inhibition of HRR does not function in cells lacking IRS‐1, and can be reproduced in the absence of T‐antigen by IRS‐1 with artificial nuclear localization signal. Our observations define a new mechanism by which viral protein utilizes cytosolic molecule to inhibit faithful DNA repair, and suggest how polyomaviruses could compromise stability of the genome. © 2005 Wiley‐Liss, Inc.
Overview and Evolution of the ADDIE Training System

The problem and the solution . The workforce of the 21st century is in a continual state of flux. This has created a need by human resource development scholars and practitioners to continue to review best practices in developing a workforce with the latest technology, knowledge, and expertise. Revisiting traditional training models and processes is important as a means of moving forward. Although there are many system models, almost all are based on the generic analysis, design, develop, implement, and evaluate (ADDIE) model that evolved from instructional systems research following World War II. The purposes of this article are to (a) reacquaint the profession with the background and basic concepts of the traditional ADDIE model and (b) compare the original and revised ADDIE models. Subsequent articles in this volume deal with issues and advancements surrounding ADDIE and the ADDIE phases.
An exploratory study of the academic engagement and beliefs of Latino male high school students

Abstract This study provides insights to the school experiences of Latino male students through an exploration of how they describe their beliefs about education and how they engage in school for academic success. Data is drawn from interviews and surveys conducted with Latino males that participated in New York University’s Black and Latino Male School Intervention Study (BLMSIS) between 2006 and 2011. The findings revealed a dynamic interplay among how the students ‘do school’ (behavioral engagement), their intellectual involvement (cognitive engagement), and their strong beliefs in the education for social mobility shaped schooling for them. This focus on the experiences of young Latino males seeks to assist researchers, policymakers, and practitioners alike design and implement programs and policies to promote their educational progress and success.
Multimedia over Wireless Mesh Networks: Results from a Real Testbed Evaluation

Wireless mesh networks are the next step in the evolution of wireless architecture, delivering services for a large variety of applications in personal, local, campus, and metropolitan areas. Unlike WLANs, mesh networks are self-configuring systems where each Access Point (AP) can relay messages on behalf of others, thus increasing the range and the available bandwidth. Key advantages of wireless mesh networks include ease of installation, no cable cost, automatic connection among nodes, network flexibility, discovery of newly added nodes, redundancy, and self-healing reliability. At UCLA Network Research Lab, we created a testbed for Wireless Mesh Networks using the Mesh Connectivity Layer, part of the Microsoft Mesh Toolkit 2005. In this paper we focus on indoor scenarios, such as home environments and offices. As the demand for rich-media, streaming video content continues to increase, this kind of applications certainly represents a main player in the considered scenarios. Using our testbed, we delineate the limits of multimedia streaming with today’s WMN technology.
Annexin XIIIb Associates with Lipid Microdomains to Function in Apical Delivery

A member of the annexin XIII sub-family, annexin XIIIb, has been implicated in the apical exocytosis of epithelial kidney cells. Annexins are phospholipid-binding proteins that have been suggested to be involved in membrane trafficking events although their actual physiological function remains open. Unlike the other annexins, annexin XIIIs are myristoylated. Here, we show by immunoelectron microscopy that annexin XIIIb is localized to the trans-Golgi network (TGN), vesicular carriers and the apical cell surface. Polarized apical sorting involves clustering of apical proteins into dynamic sphingolipid-cholesterol rafts. We now provide evidence for the raft association of annexin XIIIb. Using in vitro assays and either myristoylated or unmyristoylated recombinant annexin XIIIb, we demonstrate that annexin XIIIb in its native myristoylated form stimulates specifically apical transport whereas the unmyristoylated form inhibits this route. Moreover, we show that formation of apical carriers from the TGN is inhibited by an anti-annexin XIIIb antibody whereas it is stimulated by myristoylated recombinant annexin XIIIb. These results suggest that annexin XIIIb directly participates in apical delivery.
Estimation of migration rates and population sizes in geographically structured populations

The estimation of population parameters from genetic data can help reveal past migration patterns or past population sizes. The transformation from raw genetic data to population parameters needs a model, which should reflect the true relationships between subpopulations. Often the models are overly simplified and do not allow, for example, for differences in population sizes and differences in migration rates. I stress here the point that it is important to consider possible asymmetries in migration rates and differences in population sizes. Very recently several estimators based on the direct use of allele frequencies and based on coalescence theory have been developed. All these outperform migration rate estimators based on FST.
Staphylococcal exopolysaccharides inhibit lymphocyte proliferative responses by activation of monocyte prostaglandin production

The glycocalyx (exopolysaccharides) of Staphylococcus epidermidis has been reported to inhibit a variety of host defense mechanisms. We have examined the inhibitory effects of glycocalyx on the proliferation of human peripheral blood mononuclear cells (PBMC) and the mechanism of this inhibition. Glycocalyx isolated and partially purified under endotoxin-free conditions from defined liquid medium cultures of S. epidermidis and Staphylococcus lugdunensis inhibited the proliferative response of PBMC when added to cultures at 10 to 100 micrograms/ml. Glycocalyx-mediated inhibition of phytohemagglutinin-stimulated proliferation of PBMC required the presence of plastic-adherent peripheral blood monocytes. Culture supernatants of monocytes stimulated with glycocalyx contained a soluble factor that inhibited the proliferation of monocyte-depleted PBMC. This soluble inhibitory factor was not produced in the absence of glycocalyx or in the presence of both glycocalyx and indomethacin. Analysis of the supernatants of cultures of adherent monocytes revealed that glycocalyx from S. epidermidis and from S. lugdunensis could activate monocyte production of prostaglandin E2 (PGE2), human interleukin-1, and tumor necrosis factor alpha. The addition of purified PGE2, at the same levels of PGE2 (greater than or equal to 10(-9) M) generated in the monocyte cultures, to PBMC cultures resulted in a similar inhibition of proliferative responses. It is concluded that, contrary to previous suggestions, the bacterial glycocalyx does not have a direct inhibitory effect on T lymphocytes. However, it does appear that glycocalyx from coagulase-negative staphylococci can activate monocyte PGE2 production and that it is this activity that in turn contributes to the inhibition of T-cell proliferation.
Architecture Rationalization : From Real-World Challenges to a Methodological Solution

Architecture modeling is practiced extensively in the software industry but there is little attention paid to the traceability, verifiability and completeness of architecture designs. Deficiencies in any of these three areas in an architecture model can be costly and risky to projects. The case study reported here failed because it was deficient in all areas. We study and propose the Architecture Rationalization Method (ARM) to overcome these issues. ARM makes use of both qualitative and quantitative rationales for selecting architecture choices. Quantitative rationale uses a model based on costs, benefits and risks for choosing architecture designs. ARM also provides a method to determine when an architecture model is complete in that the level of details represented by the architecture design is sufficient.
An analysis of the perceptions of a group of external executive coaches on the key coaching attributes and skills required to facilitate a successful one-to-one coaching partnership within a business context

The growth of executive coaching has continued to increase despite difficult economic circumstances post-2008 and belief in the process appears to be at an all-time high with annual revenue reaching $2 billion globally (ICF, 2012). The realisation that professional life can be both mentally and psychologically challenging, particularly at executive level, has placed coaching practice under the spotlight. Organisations are becoming increasingly intrigued by what executive coaching can offer yet they require tangible evidence of what influences the process and what contributes to success. Much of the literature has focused on outcome from the perspective of the executive and on coaching theory which is noted as being somewhat limited up to the year 2000 (Grant, et al., 2010). From 2000 to 2009 there was a 4.5 fold increase in research (CIPD, 2012) but focus has generally remained within the confines of coaching theory and the self-evaluation of the executive. While self-evaluation studies are relevant, they can be considered somewhat unreliable and in addition, little attention has been paid to the underlying influences that lead to these outcomes. There has also been a ‘burgeoning of new ideas in the coaching orbit’ (Ives, 2008) when it comes to coaching models which has created a need for these approaches to be analysed and challenged. Even more importantly, little attention has been paid to the third side of the ‘coaching triangle’ Freas & Sherman (2004), the coach, who could be considered the driving force of the process. The views of the coach could provide insights that may be supplemented to existing findings in order to create a more holistic view of executive coaching and what impacts success. This study will first attempt to establish where exactly current research lies on the subject of what influences success in executive coaching. In addition to this, a qualitative study on the views of six executive coaches on the impact of coach-oriented factors such as knowledge of psychotherapy, business knowledge, coaching methods and coach attributes will be conducted. Comparisons will then be drawn between themes identified in existing literature and the findings of this study in order to draw conclusions and make recommendations on where research should focus its attention in the future.
Sustained Acceleration of Achievement in Reading Comprehension: The New Zealand Experience.

Schools with primarily indigenous and ethnic minorities in low socioeconomic areas have long been associated with low levels of achievement, particularly in literacy. This is true for New Zealand despite high levels of reading comprehension by international comparisons (e.g., PISA). Recent reviews of schooling improvement suggest small gains over the short term are possible with well-designed interventions, but for children in the middle primary school years, the criterion against which effective interventions need to be judged is sustained and systematic acceleration across levels of achievement in order to achieve equitable distributions of achievement. Plotting gains across time is also needed to examine whether “summer effects” can be overcome. The present quasi-experimental design study was a three-year research and development collaboration among schools, government, and researchers to raise reading comprehension through critical discussions of achievement and teacher observation data and linking research on effective comprehension practices to specific needs. The collaboration resulted in increased rates of achievement that were variable but sustained across three years. The growth model showed a step-like pattern with rapid gains over school months and a plateau over summer. Over three years this represented an average achievement gain across cohorts followed longitudinally of one year’s progress in addition to expected progress over that period with stanine effect sizes of d = 0.62. The results show the significance of testing effects against the criterion of sustained and systematic achievement and the need to examine growth over multiple calendar years to better represent the pattern of gains.
Game Theory and the Social Contract, Vol. 2: Just Playing

In Volume 1 of Game Theory and the Social Contract, Ken Binmore restated the problems of moral and political philosophy in the language of game theory. In Volume 2, Just Playing, he unveils his own controversial theory, which abandons the metaphysics of Immanuel Kant for the naturalistic approach to morality of David Hume. According to this viewpoint, a fairness norm is a convention that evolved to coordinate behavior on an equilibrium of a society's Game of Life. This approach allows Binmore to mount an evolutionary defense of Rawls's original position that escapes the utilitarian conclusions that follow when orthodox reasoning is applied with the traditional assumptions. Using ideas borrowed from the theory of bargaining and repeated games, Binmore is led instead to a form of egalitarianism that vindicates the intuitions that led Rawls to write his Theory of Justice. Written for an interdisciplinary audience, Just Playing offers a panoramic tour through a range of new and disturbing insights that game theory brings to anthropology, biology, economics, philosophy, and psychology. It is essential reading for anyone who thinks it likely that ethics evolved along with the human species.
Projective Identification and Intersubjectivity

The issue of what might constitute intersubjective relations during infancy and early childhood remains something of a puzzle within and beyond psychology. This paper considers whether the psychoanalytic concept of projective identification might supplement or enrich theoretical efforts in this domain. Following introductory comments on distinctive characteristics of Merleau-Ponty’s commentary on intersubjectivity, attention turns to psychoanalytic assumptions and presuppositions underpinning projective identification. Complementary and contrastive themes are drawn out, specifically those which highlight alternative metaphysical positions taken up within these approaches. Discussion touches on the processes involved in the emergence of projective identification and what implications the concept may have for contemporary theories of intersubjectivity in developmental psychology.
Generation of Labelled Transition Systems for Alvis Models using Haskell Model Representation

Alvis is a formal modelling language for concurrent systems with the following advantages: a graphical modelling language used to define interconnections among agents, a high level programming language used to define the behaviour of agents and the possibility of a formal model verification. An Alvis model semantics find expression in an LTS graph (labelled transition system). Execution of any language statement is expressed as a transition between formally defined states of such a model. An LTS graph is generated using Haskell representation of an Alvis model and user defined Haskell functions can be used to explore the graph. The paper deals with the problem of translation of an Alvis model into its Haskell representation and discusses possibilities of model verification with the so-called Haskell filtering functions.
A variational framework for single low light image enhancement using bright channel prior

Low light image enhancement is prerequisite in many fields, such as surveillance systems, road safety and waterway transport. In this paper, a new variational framework using bright channel prior is proposed to address the low light image enhancement problem within a single image. An alternating direction optimization method is employed to solve the variational problem. Experiment results show that the new method can better eliminate the black halo and suppressing the issues of over-enhancement and color distortion when compared with other existing methods.
Moving object detection for real-time high-quality lightweight applications on smart cameras

Here, a novel and efficient strategy for moving object detection by non-parametric modeling on smart cameras is presented. Whereas the background is modeled using only color information, the foreground model combines color and spatial information. The application of a particle filter allows the update of the spatial information and provides a priori information about the areas to analyze in the following images, enabling an important reduction in the computational requirements and improving the segmentation results.
Constructie en validatie van de Nederlandstalige Doeloriëntatie Vragenlijst (NDV).

Het doel van dit onderzoek was de constructie en validatie van de Nederlandstalige Doelorientatie Vragenlijst (NDV), een vertaling van de door Elliot & McGregor (2001) ontwikkelde, en op hun 2 x 2 taxonomie van doelorientaties gebaseerde vragenlijst. In de onderhavige steekproef (n = 360) toont de Nederlandstalige versie eveneens de verwachte vierfactorenstructuur. Echter, een nomologische netwerkanalyse leverde in plaats van een 2 x 2 factorenstructuur, een streef-vermijd-dichotomie op.
Diversity in Independent Component and Vector Analyses: Identifiability, algorithms, and applications in medical imaging

Starting with a simple generative model and the assumption of statistical independence of the underlying components, independent component analysis (ICA) decomposes a given set of observations by making use of the diversity in the data, typically in terms of statistical properties of the signal. Most of the ICA algorithms introduced to date have considered one of the two types of diversity: non-Gaussianity? i.e., higher-order statistics (HOS)? or, sample dependence. A recent generalization of ICA, independent vector analysis (IVA), generalizes ICA to multiple data sets and adds the use of one more diversity, dependence across multiple data sets for achieving an independent decomposition, jointly across multiple data sets. Finally, both ICA and IVA, when implemented in the complex domain, enjoy the addition of yet another type of diversity, noncircularity of the sources? underlying components. Mutual information rate provides a unifying framework such that all these statistical properties? types of diversity? can be jointly taken into account for achieving the independent decomposition. Most of the ICA methods developed to date can be cast as special cases under this umbrella, as well as the more recently developed IVA methods. In addition, this formulation allows us to make use of maximum likelihood theory to study large sample properties of the estimator, derive the Cramer-Rao lower bound(CRLB) and determine the conditions for the identifiability of the ICA and IVA models. In this overview article, we first present ICA, and then its generalization to multiple data sets, IVA, both using mutual information rate, present conditions for the identifiability of the given linear mixing model and derive the performance bounds. We address how various methods fall under this umbrella and give examples of performance for a few sample algorithms compared with the performance bound. We then discuss the importance of approaching the performance bound depending on the goal, and use medical image analysis as the motivating example.
Coming Out Of The Closet: Young Gay Men's Experiences In The Process Of Coming Out

Coming out of the closet is a decision that all young gay men consider, however there has been little recent research undertaken which investigates this phenomenon. The purpose of this qualitative study is to provide an account of young men's experiences in the process of coming out and a critical analysis of the influences of cultural, political and social factors which impinge on the process. A phenomenological method (utilising Colaizzi's procedural steps) will be employed to collect data and to extrapolate common themes and meanings. A purposeful sample of seven young gay men were interviewed. Data was collected from taped interviews and the researcher's field notes. The research findings will add new knowledge to youth studies research as well as providing a basis for ongoing research in the area of gay studies.