Miracle-dz/UniFAR-FTUs huggingface dataset:
The utility of peer-support in enhancing the treatment of incarcerated sexual offenders

Purpose In the quest to maximize treatment gains, recent research has shifted focus from treatment itself to the context in which treatment takes place. Such investigations have alluded to rehabilitative climate, therapeutic alliance, prison social climate, and the efficacy of group process. The purpose of this paper is to review peer-support as a mechanism via which these goals might be reached. Design/methodology/approach A review of the literature on peer-support in carceral settings was undertaken in February 2017. Findings While there is very little research exploring peer-support in the context of offender rehabilitation, there are some promising signs from many qualitative investigations that peer-led roles can bridge many gaps in support within the therapeutic context. Research limitations/implications More research on the potential negative impact of peer-support in carceral setting is needed. Practical implications This paper proposes that the implementation of peer-support programs that operate alongside treatment interventions represent an encouraging direction for the future. It is argued that prisoner-led peer-support initiatives that are characterized by shared problem solving and reciprocal emotional support can greatly reduce the anxiety prisoners face surrounding treatment. It is suggested that, through peer-support, treatment gains may be enhanced and better assimilated into program-completers’ lives. Social implications Peer-support may assist current treatment approaches with sexual offenders and could therefore potentially contribute to reductions in recidivism. Originality/value This paper is the first to review peer-support in the context of imprisonment and offender therapy. It therefore provides an important status update for future researchers wishing to investigate this topic, and outlines several priorities that such research might interrogate further.
Development and use of cloning systems for Bacteroides fragilis: cloning of a plasmid-encoded clindamycin resistance determinant

Chimeric plasmids able to replicate in Bacteroides fragilis or in B. fragilis and Escherichia coli were constructed and used as molecular cloning vectors. The 2.7-kilobase pair (kb) cryptic Bacteroides plasmid pBI143 and the E. coli cloning vector pUC19 were the two replicons used for these constructions. Selection of the plasmid vectors in B. fragilis was made possible by ligation to a restriction fragment bearing the clindamycin resistance (Ccr) determinant from a Bacteroides R plasmid, pBF4;Ccr was not expressed in E. coli. The chimeric plasmids ranged from 5.3 to 7.3 kb in size and contained at least 10 unique restriction enzyme recognition sites suitable for cloning. Transformation of B. fragilis with the chimeric plasmids was dependent upon the source of the DNA; generally 10(5) transformants micrograms-1 of DNA were recovered when plasmid purified from B. fragilis was used. When the source of DNA was E. coli, there was a 1,000-fold decrease in the number of transformants obtained. Two of the shuttle plasmids not containing the pBF4 Ccr determinant were used in an analysis of the transposon-like structure encoding Ccr in the R plasmid pBI136. This gene encoding Ccr was located on a 0.85-kb EcoRI-HaeII fragment and cloned nonselectively in E. coli. Recombinants containing the gene inserted in both orientations at the unique ClaI site within the pBI143 portion of the shuttle plasmids could transform B. fragilis to clindamycin resistance. These results together with previous structural data show that the gene encoding Ccr lies directly adjacent to one of the repeated sequences of the pBI136 transposon-like structure.
Sources of decline, turnaround strategy and HR strategies and practices: The case of Iberia Airlines

This study investigates the coevolution of the sources of decline, the turnaround strategy and the human resource strategy (HRS) at Iberia Airlines, together with the influence of employee responses to these strategies. The analysis of several moments of organisational decline at Iberia, comparing measures adopted in pre- and post-financial crisis periods, shows that, in a sector experiencing a fiercely competitive transformation that negatively affects established companies, the use of downsizing in an organisation with internal deficiencies may create further problems within the company, while an HRS based on flexibility-oriented practices and a fostering approach to strategic negotiations will improve the requisite recovery strategy.
Exploiting Fine-Grained Co-Authorship for Personalized Citation Recommendation

In the era of big scholarly data, citation recommendation is playing an increasingly significant role as it solves information overload issues by automatically suggesting relevant references that align with researchers’ interests. Many state-of-the-art models have been utilized for citation recommendation, among which graph-based models have garnered significant attention, due to their flexibility in integrating rich information that influences users’ preferences. Co-authorship is one of the key relations in citation recommendation, but it is usually regarded as a binary relation in current graph-based models. This binary modeling of co-authorship is likely to result in information loss, such as the loss of strong or weak relationships between specific research topics. To address this issue, we present a fine-grained method for co-authorship modeling that incorporates the co-author network structure and the topics of their published articles. Then, we design a three-layered graph-based recommendation model that integrates fine-grained co-authorship as well as author–paper, paper–citation, and paper-keyword relations. Our model effectively generates query-oriented recommendations using a simple random walk algorithm. Extensive experiments conducted on a subset of the anthology network data set for performance evaluation demonstrate that our method outperforms other models in terms of both Recall and NDCG.
Monoclonal antibodies and chemiluminescence immunoassay for detection of the surface protein of human T-cell lymphotropic virus

Monoclonal antibodies (MAbs) raised against human T-cell lymphotropic virus type I (HTLV-I) recognized five distinct antigenic domains of viral env gene-encoded proteins. By using recombinant env proteins and synthetic peptides as mapping antigens, it was determined that the most immunogenic region represented a central portion of the retroviral surface protein (domain 2; amino acids 165 to 191). However, only a single MAb was able to react strongly with native viral proteins. This antibody (clone 6C2) was directed to an epitope within domain 4 (amino acids 210 to 306) of the retroviral env gene and reacted with envelope proteins in both HTLV-I and HTLV-II, as determined by immunoprecipitation, solid-phase binding, and immunoblotting. No reactivity against envelope components of other human retroviruses, including human immunodeficiency virus types 1 and 2, was present. Flow cytometry data demonstrated that MAb 6C2 reacted with cell lines chronically infected with HTLV-I or HTLV-II and also with surface antigens expressed on fresh adult T-cell leukemia cells, following up-regulation with interleukin-2. By a chemiluminescence immunoassay procedure, picogram amounts of viral surface protein could be detected in the unconcentrated supernatants of HTLV-infected cell lines and in diagnostic cultures. Levels of env and gag proteins released by cells into culture supernatants were not directly related to percent expression of cell surface viral-coat proteins. Further, the molar ratio of p19 to gp46 in conditioned media varied from strain to strain, possibly reflecting differences in viral assembly or packaging mechanisms. MAb 6C2 will be of value in characterizing the biochemical and immunological behavior of retroviral env gene proteins and in studying the interaction of HTLV-I and HTLV-II with their receptors.
Chromium Supplementation for Menstrual Cycle-Related Mood Symptoms

ABSTRACT Background: Premenstrual dysphoric disorder (PMDD) afflicts ∼7% of reproductive-age women resulting in impaired relationships, diminished overall quality of life, and disability-adjusted life years lost on par with other major psychiatric disorders. Response to pharmacological treatment is inadequate in ∼50% of women with PMDD. Objective: The goal of the present study is to evaluate the effects of a novel approach—short-term chromium supplementation—on menstrual cycle-related mood and physical symptoms. Methods: Five women were studied under single-blind conditions in a private clinical setting (2 of them were referred specifically for treatment-resistant menstrual-related symptoms); 6 women completed a double-blind crossover study of chromium plus placebo versus chromium plus sertraline in a university clinical research setting. Treatments were administered from mid-cycle to onset of menses in 1-month intervals. Symptom ratings were obtained by self-report, using daily symptom checklists, and by clinical assessment, using the Hamilton Psychiatric Rating Scale for Depression (HAM-D) and the Clinical Global Impressions (CGI) scale. Results: Overall, chromium treatment was associated with reduced mood symptoms and improved overall health satisfaction in most participants. In some cases, chromium alone was associated with marked clinical improvement; in others, chromium plus an antidepressant resulted in greater improvement than either chromium alone or an antidepressant alone. Conclusion: These preliminary observations suggest that chromium may be a useful monotherapy or adjunctive therapy for women suffering from significant menstrual cycle-related symptoms. Larger, controlled studies are needed to evaluate the efficacy of chromium treatment in this patient population.
c-Space: 3D visualization and modelling of digital models on mobile devices

c-Space aims to stimulate users' creativity by giving them a set of tools that would allow the reconstruction of 3D scenes by just taking some pictures/videos of the real world. Of great importance is the possibility to exploit these tools in a mobile environment, in order to utilize the portability and accessibility offered by hand-held devices. However, the decision to support this kind of devices comes at a cost: many operations that are easily done in a desktop PC, are not in the mobile world: high loading times, complex 3D interactions and low memory are some of the faced problems. This paper introduces new metaphors of interaction that permits the editing of 3D scenes, even on displays of small sizes; moreover, it presents a visualization system that gives user extra freedom, when compared to existent tools, while keeping at the same time minimal levels of complexity.
Korean Journal for Food Science of Animal Resources Effect of Dietary Fiber Enrichment and Different Cooking Methods on Quality of Chicken Nuggets

The effect of dietary fiber enrichment (wheat bran) and cooking methods (oven, steam and microwave) on functional and physico-chemical properties of raw nuggets formulation as well as nutritional, color and textural properties of chicken nuggets were analyzed in this study. Among different cooking methods used for nuggets preparation, steam cooked nuggets had significantly (p<0.05) higher water holding capacity (56.65%), cooking yield (97.16%) and total dietary fiber content (4.32%) in comparison to oven and microwave cooked nuggets. The effect of cooking methods and wheat bran incorporation was also noticed on textural properties of the nuggets. Hardness, firmness and toughness values of oven and steam cooked nuggets were significantly (p<0.05) higher than microwave cooked nuggets. Among nuggets prepared by different cooking methods, cohesiveness of microwave cooked nuggets was found to be significantly (p<0.05) highest, whereas, oven cooked nuggets had significantly (p<0.05) highest gumminess and chewiness values. Steam cooked nuggets were found to be better among all nuggets due to their higher cooking yield and dietary fiber content.
Attention and verbal learning in patients with Chronic Fatigue Syndrome

Former neuropsychological studies with Chronic Fatigue Syndrome (CFS) patients evaluated a broad range of cognitive functions. Several, but not all, reported subtle attentional and memory impairments suggesting possible mild cerebral involvement. In this study, a battery of attentional tests and a verbal memory task were administered to 20 CFS patients and 22 healthy controls (HC) in order to clarify the specific nature of attention and memory impairment in these patients. The results provide evidence for attentional dysfunction in patients with CFS as compared to HC. CFS patients performed more poorly on a span test measuring attentional capacity and working memory. Speeded attentional tasks with a more complex element of memory scanning and divided attention seem to be a sensitive measure of reduced attentional capacity in these patients. Focused attention, defined as the ability to attend to a single stimulus while ignoring irrelevant stimuli, appears not to be impaired. CFS patients were poorer on recall of verbal information across learning trials, and poor performance on delayed recall may be due to poor initial learning and not only to a retrieval failure. (JINS, 1998, 4, 456–466.)
mlpy: Machine Learning Python

mlpy is a Python Open Source Machine Learning library built on top of NumPy/SciPy and the GNU Scientific Libraries. mlpy provides a wide range of state-of-the-art machine learning methods for supervised and unsupervised problems and it is aimed at finding a reasonable compromise among modularity, maintainability, reproducibility, usability and efficiency.mlpy is multiplatform, it works with Python 2 and 3 and it is distributed under GPL3 at the website http://mlpy.fbk. eu.
The radiology report as seen by radiologists and referring clinicians: results of the COVER and ROVER surveys.

PURPOSE To investigate and compare the opinions and expectations regarding the radiology report of radiologists and referring clinicians and to identify trends, discordance, and discontent. MATERIALS AND METHODS A total of 3884 clinicians and 292 radiologists were invited by e-mail to participate in two internet surveys, COVER (for clinical specialists and general practitioners) and ROVER (for radiologists). Respondents were asked to state their level of agreement with 46 statements according to a Likert scale. Dichotomized results were compared by using the χ(2) statistic. RESULTS Eight hundred seventy-three completed forms were prepared for analysis, corresponding to a response rate of 21%. Most clinicians declared themselves satisfied with the radiology report. A large majority considered it an indispensable tool and accepted that the radiologist is the best person to interpret the images. Nearly all agreed that they need to provide adequate clinical information and state clearly what clinical question they want to have answered. Itemized reporting was preferred for complex examinations by both the clinicians and the radiologists. A majority in both groups were convinced that learning to report needs to be taught in a structured way. CONCLUSION The surveys emphasize the role of the radiologist as a well-informed medical imaging specialist; however, some of the preferences of radiologists and clinicians diverge fundamentally from the way radiology is practiced and taught today, and implementing these preferences may have far-reaching consequences.
Control of IL-2 R α gene expression : structural changes within the proximal enhancer / core promoter during T-cell development

During T-cell development in thymus, CD25, the IL-2 receptor α chain (IL-2Rα) is already expressed in early double-negative (DN) thymocytes where commitment to T-cell lineage has been established, but subsequently IL-2Rα is dramatically downregulated for the remainder of T-cell development. The loss of IL-2Rα expression after expression of the pre-TCR α:β complex on the cell surface is essential for the later specific responses of mature T cells. Using appropriate mouse models and DMS genomic footprinting, we showed that the TATA box in the core promoter region of the murine IL-2Rα locus was occupied only in DN CD25+ T cells. Further, by chromatin immunoprecipitation assays, we evidenced that down-regulation of IL-2Rα transcription correlated with (i) loss of the basal transcriptional machinery; (ii) dissociation of histone acetylase p300 and BRG1, a member of the ATP-dependent chromatin remodeling complex SWI/SNF; and (iii) histone N-termini dephosphorylation plus deacetylation. In contrast, occupancy of the proximal enhancer region (positive regulatory region I) was not detected by in vivo genomic footprinting though constitutive accessibility of the promoter region for DNase I digestion both in the DN and double-positive stages correlated with the constitutive association of CBP and PCAF to the IL-2Rα core promoter. These results exemplify one mechanism by which a promoter enables transcription to switch on and off during T-cell differentiation.
Encouraging Tax-Time Savings with a Low-Touch, Large-Scale Intervention: Evidence from the Refund to Savings Experiment

Low‐ and moderate‐income households often struggle to save, but the annual tax refund represents a prime opportunity for these households to save toward their financial goals or build their emergency savings. This paper presents the results of a randomized, controlled experiment embedded in a free tax‐preparation product offered in 2013 to low‐ and moderate‐income households. The experiment involved approximately 470,000 filers and assessed the impact of behavioral interventions on their savings behaviors. The results show that filers exposed to the treatments, which involved the established behavioral‐economics techniques of anchoring, choice architecture, and persuasive messaging, were more likely than a control group to save their tax refund and, on average, saved more of the refund. A follow‐up survey of these tax filers found that the treatments were associated with saving more of the tax refund six months after filing. The findings also show that anchors encouraging filers to deposit certain amounts are more effective than persuasive messaging emphasizing savings.
Trade Partnerships and Environmental Performance in Developing Countries

A large scholarship surrounds the relationship between trade and the environment, with much of it centering on whether trade produces a race to the bottom or a race to the top in the environments of developing countries. While the effects of trade on key pollutants and on specific environmental policies have been widely attended to, scholars have not yet considered if and how trade impacts developing nations’ environmental performance, broadly speaking. This is a critical matter, as the effects of trade on the environment can only be appreciated fully through holistic assessment of the environment and environmental protection. The study that follows helps to fill this void through analysis of an all-inclusive measure of environmental performance that encompasses indicators of policy and practice. Findings demonstrate that exporting to the United States and the European Union improves environmental performance in developing countries; however, no such effect accompanies trade with other countries.
Fulfilling the social contract between medical schools and the public

To gain a better understanding of the effects of medical schools related to transformations in medical practice, science, and public expectations, the Association of American Medical Colleges (AAMC) established the Advisory Panel on the Mission and Organization of Medical Schools (APMOMS) in 1994. Recognizing the privileges academic medicine enjoys as well as the power of and the strain on its special relationship with the American public, APMOMS formed the Working Group on Fulfilling the Social Contract. That group focused on the question: What are the roles and responsibilities involved in the social contract between medical schools and various interested communities and constituencies? This article reports the working group's findings. The group describes the historical and philosophical reasons supporting the concept of a social contract and asserts that medical schools have individual and collective social contracts with various subsets of the public, referred to as "stakeholders. " Obligations derive implicitly from the generous public funding and other benefits medical school receive. Schools' primary obligation is to improve the nation's health. This obligation is carried out most directly by educating the next generation of physicians and biomedical scientists in a manner that instills appropriate professional attitudes, values, and skills. Group members identified 27 core stakeholders (e.g., government, patients, local residents, etc.) and outlined the expectations those stakeholders have of medical schools and the expectations medical schools have of those stakeholders. The group conducted a survey to test how leaders at medical schools responded to the notion of a social contract, to gather data on school leaders' perceptions of what groups they considered their schools' most important stakeholders, and to determine how likely it was that the schools' and the stakeholders expectations of each other were being met. Responses from 69 deans suggested that the survey provoked thinking about the broad issue of the social contract and stakeholders. Leaders on the same campuses disagreed about what groups were the most important stakeholders. Similarly, the responses revealed a lack of national consensus about the most important stakeholders, although certain groups were consistently included in the responses. The group concludes that medical school leaders should examine their assumptions and perspectives about their institutions' stakeholders and consider the interests of the stakeholders in activities such as strategic planning, policymaking, and program development.