Miracle-dz/UniFAR-FTUs huggingface dataset:
Ethylene and auxin interaction in the control of adventitious rooting in Arabidopsis thaliana

Highlight Ethylene affects adventitious rooting by reducing indole-3-acetic acid (IAA) biosynthesis, but enhancing conversion into IAA of its precursor indole-3-butyric acid (IBA). This conversion, together with active IAA-cellular-influx, is essential for adventitious root formation.
Da revisão de texto à revisão de texto crítica: uma nova perspectiva profissional - doi:10.5102/univhum.v7i1.897

A Revisao de Texto nao envolve apenas a adequacao do genero a ser revisado a modalidade-padrao da lingua portuguesa. Pensar-se assim torna a atividade superficial, uma vez que essa pratica se insere em uma subjetividade cujos elementos se revelam muito mais complexos. Por isso a importância deste trabalho para contribuir na transformacao da atividade de Revisao de Texto em uma perspectiva critica. De outra parte, a Revisao de Texto possui funcao social. Desse modo, deve-se considerar, veementemente, que tal pratica alcanca horizontes que vao alem do texto escrito. Sendo assim, sua pratica precisa ser analisada a partir de visoes macros, que considerem as relacoes suscitantes dessa atividade – entre linguagem e sociedade; linguagem e poder; linguagem e identidade. Dessa forma, o objetivo desta pesquisa e Repensar a atividade de Revisao de Texto em uma perspectiva critica para acompanhar as novas mudancas nos estudos da linguagem e aplica-la nas atividades que envolvem analise de texto. Minha fundamentacao teorica baseia-se, principalmente, na Analise de Discurso Critica (ADC), nos trabalhos de Fairclough (2001, 2003); na Teoria dos Generos Discursivos, Bakhtin (1997) e Marcuschi (2002).
Cullin-1 Promotes Cell Proliferation in Human Breast Cancer and is Related to Diabetes

Aim Breast carcinoma (BCA) and diabetes mellitus (DM) are two major health problems in women and the general population. Cullin-1 is reported to be an important tumor-related protein involved in cell-cycle progression, signal transduction and transcription. The aim of this work is to investigate the role of Cullin-1 in the development of BCA and to find potential relationships between Cullin-1 and diabetes in BCA patients. Methods To evaluate the function of Cullin-1, we entered 168 patients with primary invasive BCA in this study. Pairs of BCA tissues and adjacent noncancerous tissues from these patients were collected between 2006 and 2008. We used immunohistochemistry to analyze the correlation between Cullin-1 expression and clinicopathological variables and patient survival. In addition, we investigated the role of Cullin-1 in BCA cell proliferation. Results Cullin-1 expression was upregulated in BCA tissues. Enhanced immunoreactivity for Cullin-1 in BCA tissues was inversely correlated with overall survival and disease-free survival, which suggested a poor prognosis in BCA patients. Strong expression of Cullin-1 was more frequently observed in patients with estrogen receptor negativity and HER2 positivity. We also found that Cullin-1 expression was increased in BCA patients with a previous diagnosis of diabetes. Conclusions Our results demonstrate that increased Cullin-1 expression is significantly correlated with poor prognosis in patients with BCA. Cullin-1 might regulate BCA cell proliferation through the ubiquitin-proteasome system. Thus, Cullin-1 might be an important marker and a therapeutic target in BCA.
Effect of Route Reflection on IBGP Convergence and an approach to reduce convergence time

Request for Comments (RFCs) for Border gateway Protocol (BGP) suggest that the network topology using BGP must have full mesh of IBGP sessions to avoid routing loops. Routing loop is a condition where packets are routed between two or more routers resulting in slow convergence and routing instability. Route reflection is one of the strategies to avoid full mesh of internal BGP sessions between BGP speaking routers in an autonomous system. This paper focuses on demonstrating an effect of using route reflection on convergence time in a small network. A mixed network scenario of external and internal BGP sessions is considered for demonstration. Results of the simulation have shown that, route reflection can significantly increase the convergence time avoiding full mesh. Also an approach to reduce the convergence time has been proposed. Proposed algorithm is based on the principle of creating logical group of router reflectors. The same concept can be scaled for larger networks for different scenarios.
Sexual dysfunction among young men : prevalence and associated factors

Purpose: The purposes of this study are to measure the prevalence of premature ejaculation (PE) and erectile dysfunction (ED) among a population of Swiss young men and to assess which factors are associated with these sexual dysfunctions in this age-group. Methods: For each condition (PE and ED), we performed separate analyses comparing young men suffering from the condition with those who were not. Groups were compared for substance use (tobacco, alcohol, cannabis, other illegal drugs, and medication without a prescription), selfreported body mass index, sexual orientation, physical activity, professional activity, sexual experience (sexual life length and age at first intercourse), depression status,mental health, andphysical health in a bivariate analysis.We then used a log-linear analysis to consider all significant variables simultaneously. Results: Prevalence rates for PE and EDwere 11% and 30%, respectively. Poormental healthwas the only variable to have a direct association with both conditions after controlling for potential confounders. In addition, PE was directly associated with tobacco, illegal drugs, professional activity, and physical activity, whereas ED was directly linked with medication without a prescription, length of sexual life, and physical health. Conclusions: In Switzerland, one-third of young men suffer from at least one sexual dysfunction. Multiple health-compromising factors are associated with these dysfunctions. These should act as red flags for health professionals to encourage them to take any opportunity to talk about sexuality with their young male patients. 2012 Society for Adolescent Health and Medicine. All rights reserved. IMPLICATIONS AND
Reconfigurable unit-cells for beam-scanning transmitarrays in X band

Two different designs of electronically reconfigurable unit-cells with 1-bit phase quantization are studied for beam scanning transmitarrays in X band. These two unit-cells are printed on two identical Rogers RO4003 substrates and are composed of four metal layers (passive patch - ground plane - bias lines - active patch). In the first case, two p-i-n diodes are integrated on the active patch in order to control electronically the transmission phase. The experimental performances of this unit-cell are in very good agreement with the full-wave simulations. The measured insertion loss and 3-dB transmission bandwidth are equal to 2.1 dB and about 15% respectively. As the insertion loss strongly depends on the series resistance of the p-i-n diodes in the ON-state, a second unit-cell design based on RF-MEMS switches is presented. The theoretical performances of this second structure exhibit very low insertion loss (0.8 dB) and a broad 3-dB transmission bandwidth of 16%.
Violent behaviour detection using local trajectory response Conference

Surveillance systems in the United Kingdom are prominent, and the number of installed cameras is estimated to be around 1.8 million. It is common for a single person to watch multiple live video feeds when conducting active surveillance, and past research has shown that a person’s effectiveness at successfully identifying an event of interest diminishes the more monitors they must observe. We propose using computer vision techniques to produce a system that can accurately identify scenes of violent behaviour. In this paper we outline three measures of motion trajectory that when combined produce a response map that highlights regions within frames that contain behaviour typical of violence based on local information. Our proposed method demonstrates state-of-the-art classification ability when given the task of distinguishing between violent and non-violent behaviour across a wide variety of violent data, including real-world surveillance footage obtained from local police organisations.
The Phonetic and Phonological Analysis of the Fall-Rise Intonation Pattern in the Kihnu Variety of Estonian

The paper presents an analysis of fall-rise intonation patterns in the Kihnu dialect of Estonian. The study is based on recordings of spontaneous speech from three generations of female speakers. Fall-rises occurred almost five times less frequently in the data of the speakers born around 1935 as compared to those born around 1900. The data of the speakers born after 1970 did not contain any fall-rises at all, which could be interpreted as a sign of prosodic levelling of the traditional variety. An investigation of F0 alignment revealed a systematic variation in the location of high and low tonal targets. The peaks were aligned significantly later in the case of longer phrases. The first low elbow was aligned either with the accented syllable (in monosyllabic and disyllabic words) or with the syllable following the accented syllable (in longer words and phrases), and the second low elbow with the final syllable of the phrase just before the high boundary. These findings lend support to the treatment of the fall-rise accent as H*L H% in accordance with the autosegmental-metrical analysis of Estonian intonation.
The Importance of Size and Disorder in the Cryoprotective Effects of Dehydrins1[C][W]

The ability of dehydrins to efficiently protect enzymes from freeze-thaw damage is determined by their length and flexibility. Dehydrins protect plant proteins and membranes from damage during drought and cold. Vitis riparia K2 is a 48-residue protein that can protect lactate dehydrogenase from freeze-thaw damage by preventing the aggregation and denaturation of the enzyme. To further elucidate its mechanism, we used a series of V. riparia K2 concatemers (K4, K6, K8, and K10) and natural dehydrins (V. riparia YSK2, 60 kilodalton peach dehydrin [PCA60], barley dehydrin5 [Dhn5], Thellungiella salsuginea dehydrin2 [TsDHN-2], and Opuntia streptacantha dehydrin1 [OpsDHN-1]) to test the effect of the number of K-segments and dehydrin size on their ability to protect lactate dehydrogenase from freeze-thaw damage. The results show that the larger the hydrodynamic radius of the dehydrin, the more effective the cryoprotection. A similar trend is observed with polyethylene glycol, which would suggest that the protection is simply a nonspecific volume exclusion effect that can be manifested by any protein. However, structured proteins of a similar range of sizes did not show the same pattern and level of cryoprotection. Our results suggest that with respect to enzyme protection, dehydrins function primarily as molecular shields and that their intrinsic disorder is required for them to be an effective cryoprotectant. Lastly, we show that the cryoprotection by a dehydrin is not due to any antifreeze protein-like activity, as has been reported previously.
The effect of chlorhexidine on plaque index and mutans streptococci in orthodontic patients: A pilot study

Aim: The purpose of this study was to assess chlorhexidine effects on plaque index and salivary levels of mutans streptococci (MS) when used as the immersion solution for removable orthodontic appliances and added to their acrylic resin composition. Methods: Forty-five patients (6 to 12 years old) were randomly assigned into three groups with 15 patients each. Group I (control)—without orthodontic appliances disinfection; Group II—removable orthodontic appliances which had been immersed in 0.12% chlorhexidine digluconate overnight (8 hours), and Group III—orthodontic appliances in which 0.12% chlorhexidine digluconate solution had been incorporated into their resin composition. Saliva was collected for quantification of MS and evaluation of plaque index was performed before and after installation of orthodontic appliance at 0, 2, 4, 6, 8, and 10 weeks. Data were analyzed by using analysis of variance. Results: Number of MS colonies in saliva and plaque index showed no statistically differences among groups at the different periods (p > 0.05). Conclusions: It could be concluded that chlorhexidine incorporation into the acrylic resin of removable orthodontic appliances at 0.12% concentration and immersion of the appliance into 0.12% chlorhexidine solution were not effective in reducing plaque index and the number of MS in saliva.
The transcription factor Snf1p is involved in a Tup1p-independent manner in the glucose regulation of the major methanol metabolism genes of Hansenula polymorpha

Hansenula polymorpha is a methylotrophic yeast widely employed in biotechnology as a ''protein factory''. Most promoters used for heterologous protein expression, like MOX (methanol oxidase) and DAS (di-hydroxy acetone synthase), are involved in the peroxisomal methanol metabolism (C1 metabolism) and are under strong glucose repression. Interestingly, the MOX promoter is subjected to glucose regulation also in Saccharomyces cerevisiae, a non-methylotrophic yeast in which this phenomenon is well studied. In this species, the transcription factor Tup1p plays an essential role in glucose repression of several genes. This effect is counteracted by the activator Snf1p when glucose is exhausted from medium. Therefore, to test whether this regulatory circuit has been conserved in H. polymorpha, HpTUP1 and HpSNF1 were partially cloned and disrupted. Deletion of HpTUP1 did not affect glucose repression of the major C1 metabolism genes (MOX, DAS). Thus, though conserved, HpTUP1 does not seem to take part in a general glucose repression in H. polymorpha. In contrast, the deletion of HpSNF1 led to significant decreases in the activation of these genes in the absence of glucose. Therefore, the effect of HpSNF1 in transcriptional activation may be through an HpTUP1- independent circuit.
Image mosaics algorithm based on feature points matching

Several common used image mosaics algorithms are analyzed and compared and new algorithm based on feature points matching is presented, in which stitch points is determined through finding corresponding feature points of two images and its matching position is determined; Image mosaics are accomplished through fusing process in overlapping area and experiment is carried out in order to test the algorithm presented in the paper lastly. Experiment proves responsibility of algorithm proposed in this paper and good result is gained.
Transformed Neighborhood Propagation

An enhanced label propagation technique termed transformed neighborhood propagation (TNP) is proposed for semi-supervised learning. In the TNP setting, the processes of constructing weighted similarity graph and propagating label information of the labeled data to unlabeled points are conducted in the transformed feature space. TNP is mainly motivated by a fact that the optimal feature representation Y with possible unfavorable features and noises in the original data X removed by feature learning are more appropriate and accurate for measuring pair wise similarities of samples. To achieve the representation Y, The recent marginal semi-supervised sub-manifold projections is applied, so enhanced inter-class separation and enhanced intra-class compactness are delivered at the same time. The similarity graph is finally constructed based on Y. We also propose to calculate semi-supervised reconstruction weights for the weight assignment. As a result, the label estimation power can be enhanced by benefiting from the refined weighted similarity graph over Y instead of X, through propagating the labels of points in the transformed space for prediction. Visualization and image classification verified the effectiveness of our TNP, compared with other related label propagation algorithms.
Absorption, metabolism, and excretion of 14C-temozolomide following oral administration to patients with advanced cancer.

The purpose of this study is to characterize the absorption, metabolism, and excretion of carbon 14-labeled temozolomide (14C-TMZ) administered p.o. to adult patients with advanced solid malignancies. On day 1 of cycle 1, six patients received a single oral 200-mg dose of 14C-TMZ (70.2 microCi). Whole blood, plasma, urine, and feces were collected from days 1-8 and on day 14 of cycle 1. Total radioactivity was measured in all samples. TMZ, 5-(3-methyltriazen-1-yl)imidazole-4-carboxamide (MTIC), and 4-amino-5-imidazole-carboxamide (AIC) concentrations were determined in plasma, and urine and plasma samples were profiled for metabolite/degradation products. Maximum TMZ plasma concentrations were achieved between 0.33 to 2 h (mean, 1.2 h), and half-life, apparent volume of distribution, and oral clearance values averaged 1.9 h, 17 liters/m2, and 104 ml/min/m2, respectively. A first-order absorption, one-compartment linear model, which included first-order formation of MTIC from TMZ and elimination of MTIC via degradation to AIC, and a peripheral distribution compartment for AIC, adequately described the plasma TMZ, MTIC, and AIC concentrations. MTIC systemic clearance was estimated to be 5384 ml/min/m2, and the half-life was calculated to be 2.5 min. Metabolite profiles of plasma at 1 and 4 h after treatment showed that 14C-derived radioactivity was primarily associated with TMZ, and a smaller amount was attributed to AIC. Profiles of urine samples from 0-24 h revealed that 14C-TMZ-derived urinary radioactivity was primarily associated with unchanged drug (5.6%), AIC (12%), or 3-methyl-2,3-dihydro-4-oxoimidazo[5,1-d]tetrazine-8-carboxyl ic acid (2.3%). The recovered radioactive dose (39%) was principally eliminated in the urine (38%), and a small amount (0.8%) was excreted in the feces. TMZ exhibits rapid oral absorption and high systemic availability. The primary elimination pathway for TMZ is by pH-dependent degradation to MTIC and further degradation to AIC. Incomplete recovery of radioactivity may be explained by the incorporation of AIC into nucleic acids.
User Verification from Walking Activity - First Steps towards a Personal Verification System

In this work, first encouraging results in user verification by walking activity using a wearable device are reported. A discriminative machine learning pipeline is proposed for user verification. A general walking classifier based on AdaBoost is used for personalization adding data related to the verified users. An ensemble of One-Class classifiers is created for user verification. This novel technique proves to achieve very high performances from both classification accuracy and computational cost point of view. Results obtained shows that users can be verified with high confidence, with very high value of performance metrics.
Chapter 3 3 D Multiscale Modelling of Angiogenesis and Vascular Tumour Growth

We present a three-dimensional, multiscale model of vascular tumour growth, which couples nutrient/growth factor transport, blood flow, angiogenesis, vascular remodelling, movement of and interactions between normal and tumour cells, and nutrient-dependent cell cycle dynamics within each cell. We present computational simulations which show how a vascular network may evolve and H. Perfahl (*) • A. Lapin • M. Reuss Center for Systems-Biology, University of Stuttgart, Stuttgart, Germany e-mail: perfahl@ibvt.uni-stuttgart.de; lapin@ibvt.uni-stuttgart.de; reuss@ibvt.uni-stuttgart.de H.M. Byrne Oxford Centre for Collaborative Applied Mathematics, Department of Computer Science, University of Oxford, Oxford, UK e-mail: helen.byrne@maths.ox. ac.uk T. Chen • V. Estrella • R.A. Gatenby • R.J. Gillies • M.C. Lloyd H. Lee Moffitt Cancer Center & Research Institute, Tampa FL 33612, USA e-mail: tingan.chen@moffitt.org; veronica.estrella@moffitt.org; robert.gatenby@moffitt.org; robert.gillies@moffitt.org; mark.lloyd@moffitt.org T. Alarcón Centre de Recerca Matemàtica, Campus de Bellaterra, Barcelona, Spain e-mail: talarcon@crm.cat P.K. Maini Centre for Mathematical Biology, Mathematical Institute and Oxford Centre for Integrative Systems Biology, Department of Biochemistry, University of Oxford, Oxford, UK e-mail: maini@maths.ox. ac.uk M.R. Owen Centre for Mathematical Medicine and Biology, School of Mathematical Sciences, University of Nottingham, Nottingham, UK e-mail: markus.owen@nottingham.ac.uk The chapter is based on Perfahl et al., 2011,Multiscale Modelling of Vascular Tumour Growth in 3D: The Roles of Domain Size and Boundary Conditions. PLoS ONE 6(4): e14790. doi:10.1371/ journal.pone. 0014790 M.W. Collins and C.S. König (eds.), Micro and Nano Flow Systems for Bioanalysis, Bioanalysis 2, DOI 10.1007/978-1-4614-4376-6_3, # Springer Science+Business Media New York 2013 29 interact with tumour and healthy cells. We also demonstrate how our model may be combined with experimental data, to predict the spatio-temporal evolution of a vascular tumour.
Garantir o direito à educação sob a lógica performática: um estudo na Escola de Leitores

Este artigo pretende discutir a garantia do direito a educacao sob a logica performatica devido as transformacoes no setor publico que ocorrem em diferentes paises, inclusive no Brasil. Para tal discussao, parto dos dados coletados na pesquisa de doutorado da autora, que analisou a politica educativa da cidade do Rio de Janeiro (2009-2012), observando o papel da coordenadora pedagogica na “implementacao” dessa politica na escola. A questao da pesquisa e: quais foram os ajustamentos secundarios realizados pela coordenadora junto com as professoras ao “implementar” a proposta educativa baseada na logica performatica, considerando sempre a defesa da educacao como um direito? Busco responde-la baseando no conceito de performatividade e novo gerencialismo desenvolvidos por Stephen Ball. Os dados apresentados evidenciam que os educadores da escola fizeram alguns ajustamentos na proposta da Secretaria Municipal Educacao (SME), buscando assegurar o direito a educacao dos alunos. Uma das modificacoes observadas se refere as competicoes propostas para que as criancas pudessem cumprir com as regras da escola. Outro ajustamento foi percebido em relacao a categoria avaliacao, uma vez que a pressao de a escola ter que alcancar uma meta estabelecida pela SME influenciou a pratica da coordenadora que passou a discutir as metas e os resultados da escola em relacao a rede, trazendo graficos de desempenho dos alunos em todos os Conselhos de Classe. Ao mesmo tempo, porem, a coordenadora e as professoras desenvolviam um trabalho coletivo em torno dos projetos de leitura e escrita, que se tornou uma estrategia para enfrentar a cultura da performatividade.
Design of a multi-winding high-frequency transformer for DC-DC applications

DC network is one of the key facilities to realize energy internet and energy system integration. For DC-DC converters, which are energy hubs in DC networks, multi-winding high-frequency transformer can be used to realize the balance of power and voltage of each module in order to simplify system design. This paper proposes a design methodology of multi-winding high-frequency transformer for DC-DC applications including leakage inductance calculation, losses analysis and cooling system design. The method is applied to design a multi-winding transformer according to specific specifications. Finite element simulation results of the multi-physical field of the transformer show that the proposed method has high accuracy and practicability.