Miracle-dz/UniFAR-FTUs huggingface dataset:
Subjective and Projective Measures of Thesis Writing Procrastination: Real World and The Sims World.

Although it has been studied since 1980s, the theoretical framework for procrastination has just been comprehensively developed about two decades later. This study applied Temporal Motivation Theory (TMT) as a theoretical framework to develop thesis writing procrastination instruments, using self report and Sim’s behavior observation methods. Self-report results of 232 undergraduate students have fulfilled psychometric norms, concerning either the reliability or validity aspects. Observation of Sim’s behaviors, performed by 48 students, also fulfilled some of the psychometric criteria. The discovery of contradictory patterns of academic activities in the real world against The Sims 2 World was perceived as evidences of basic value differences and manifestation of defense mechanism. Inclusion of subject’s responses on The Sims 2 game play pattern scale in the hierarchical linear regression equation improved the prediction power toward latency of thesis completion. Keyword : multi-methods, procrastination, Temporal Motivation Theory, The Sims , thesis Sekalipun telah dipelajari sejak 1980-an, kerangka kerja teoretis penunda-nundaan (prokrastinasi) baru tersusun secara komprehensif sekitar dua dekade kemudian. Penelitian ini menggunakan kerangka kerja teoretis Teori Motivasi Temporal (Temporal Motivation Theory /TMT) untuk mengembangkan alat ukur penunda-nundaan pengerjaan tugas akhir dengan laporan diri dan pengamatan perilaku sim . Hasil pengukuran laporan diri terhadap 232 mahasiswa telah memenuhi kaidah psikometris baik dari segi reliabilitas maupun validitas. Hasil pengamatan terhadap perilaku sim yang dikendalikan 48 mahasiswa juga telah memadai dari segi reliabilitas dan validitas. Ditemukannya pola berlawanan antara pengerjaan kegiatan akademik pada dunia nyata dan dunia The Sims 2 , dimaknai sebagai bukti adanya perbedaan nilai dasar serta perwujudan mekanisme pertahanan diri. Penambahan prediktor berupa pola bermain The Sims 2 berhasil meningkatkan daya prediksi terhadap latensi penyelesaian skripsi. Kata kunci : metode pengukuran majemuk, penunda-nundaan, prokrastinasi, skripsi, Teori Motivasi Temporal, The Sims .
A spoken language system for automated call routing

We are interested in the problem of understanding fluently spoken language. In particular, we consider people's responses to the open-ended prompt of "How may I help you? ". We then further restrict the problem to classifying and automatically routing such a call, based on the meaning of the user's response. Thus, we aim at extracting a relatively small number of semantic actions from the utterances of a very large set of users who are not trained to the system's capabilities and limitations. In this paper, we describe the main components of our speech understanding system: the large vocabulary recognizer and the language understanding module performing the call-type classification. In particular, we propose automatic algorithms for selecting phrases from a training corpus in order to enhance the prediction power of the standard word n-gram. The phrase language models are integrated into stochastic finite state machines which outperform standard word n-gram language models. From the speech recognizer output we recognize and exploit automatically-acquired salient phrase fragments to make a call-type classification. This system is evaluated on a database of 10 K fluently spoken utterances collected from interactions between users and human agents.
Pharmacokinetics of ciprofloxacin after single intravenous and repeat oral administration to cats.

The pharmacokinetic properties of ciprofloxacin, a second-generation fluoroquinolone, were investigated in six cats after single intravenous and repeat oral administration at a dosage of 10 mg/kg b.i. d. Ciprofloxacin serum concentration was analyzed by microbiological assay using Klebsiella pneumoniae ATCC 10031 as microorganism test. Serum ciprofloxacin disposition was best fitted to a bicompartmental and a monocompartmental open models with first-order elimination after intravenous and oral dosing respectively. After intravenous administration, distribution was rapid (t(1/2(d)), 0.22 +/- 0.23 h) and wide as reflected by the steady-state volume of distribution of 3.85 +/- 1.34 L/kg. Furthermore, elimination was rapid with a plasma clearance of 0.64 +/- 0.28 L/h.kg and a t(1/2(el)) of 4.53 +/- 0.74 h. After repeat oral administration, absorption was rapid with a half-life of 0.23 +/- 0.22 h and T(max) of 1.30 +/- 0.67 h. However bioavailability was low (33 +/- 12%), the peak plasma concentration at steady-state was 1.26 +/- 0.67 microg/mL. Drug accumulation was not significant after seven oral administrations. When efficacy predictors were estimated ciprofloxacin showed a good profile against gram-negative bacteria when administered either intravenously or orally, although its efficacy against gram-positive microorganisms is lower.
Facilitating side channel analysis by obfuscation for Hardware Trojan detection

Integrated Circuit (IC) piracy and malicious alteration, named as Hardware Trojan (HT), are two important threats which may happen in untrusted foundries. Functionality obfuscation has been proposed against IP/IC piracy. Obfuscation can also offer opportunities to defeat HT insertion, because the HT designer cannot understand the functionality of the obfuscated ICs. In addition various HT detection methods have been proposed based on conventional functional or structural tests, and side channel analysis. Conventional functional or structural tests are inefficient if the HT is not completely activated. HT detection by side channel analysis faces Process Variation (PV) and Environment Variation (EV). An HT is detectable if its effect is significant among PV and EV. In this work we propose to use obfuscation methods to facilitate power and path delay analysis based HT detection methods. Since shorter paths have less PV than longer paths; the first approach is to generate shorter paths for nets that only belong to long paths, while the circuit is being obfuscated. The second suggested approach is to increase the proportion of HT dynamic power to the total dynamic power of circuit, while the circuit is being obfuscated. The success of power analysis based HT detection methods is increased by increasing this proportion.
A Systematic Observational Study of a Juvenile Drug Court Judge

ABSTRACT Theshiftofthejuvenilejusticesystemfromitsinitialrehabilitativeidealtowardamorepunitive orientation highlights the need to systematically document key elements of thejuvenile drug court model. In particular, it is important to clearly document the role of thejuvenilecourtjudgebecauseheorsheisconsideredvitaltothisprogrammodel. Thecurrentstudyusedparticipantobservationaswellasconﬁdentialquestionnairesonwhichyouthsharedtheirperceptionsofthejudge. Findingsshowthejudge-participantinteractionstypicallywerebrief,variedbytheparticipants’levelofcompliancewiththeprogram,andthatsanctionsweregiventwiceasoftenasrewards.Youthperceivedthejudgetobefair,respectful,andconcernedabout their lives. Discussion focuses on the signiﬁcant opportunity that juvenile drug courtjudges have for positively inﬂuencing the lives of drug-involved youth. jfcj_1066 19.36 Over the past two decades, the juvenile court system has shifted from its originalrehabilitative ideals toward a more punitive orientation, emphasizing that youthful offendersmust take responsibility and be punished for their delinquent acts (Feld, 2007; Hurst, 1999). Although balanced and restorative justice and deterrence continue as philosophical guidancefor many juvenile justice agencies, the punitive focus remains paramount in the mind of thepublic and many practitioners (Snyder & Sickmund, 2006). This punitive focus is reﬂected inmediareferencestojuvenileoffendersascriminalsandtermslike“juvenilearrest”and“juvenileprison” used to describe the activities of the juvenile justice system (Feld, 2007; Moak &Hutchinson Wallace, 2003). Some authors argue the juvenile court system has become
Apoptosis Induced by Differentiation or Serum Deprivation in an Immortalized Central Nervous System Neuronal Cell Line

Abstract: To characterize the nature of programmed cell death (PCD) induced in neuronal cells during development, three regulators of apoptosis were investigated: one, the bcl‐2‐related genes, modulate cell survival, and the other two, the interleukin‐1β converting enzyme (ICE)‐related enzymes and the tumor suppressor protein p53, have been implicated as mediators of apoptosis. These regulators were studied in H19‐7 cells, an SV40 Tts‐immortalized rat hippocampal neuronal cell line that can be differentiated with basic fibroblast growth factor at the nonpermissive temperature, resulting in a rapid attrition of cells by apoptosis. PCD occurred by two mechanisms in H19‐7 cells: The first was initiated by removal of serum from undifferentiated cells, and the second was a consequence of neuronal differentiation. In differentiated H19‐7 cells, the survival time was increased by both human bcl‐2 and bcl‐xL, and this could be reversed by bcl‐xS.Addition of a peptide inhibitor of the ICE enzyme family to H19‐7 cells resulted in a transient protection against differentiation‐associated apoptosis, whereas no further protection was observed in the BCL‐2‐ or BCL‐XL‐expressing cells. Shifting the differentiated cells to 33°C to inactivate p53 did not significantly affect the apoptotic process, indicating that apoptosis induced by neuronal differentiation is not dependent on the continued presence of p53. By contrast, in undifferentiated cells, cell loss induced by transfer to serum‐free media occurred more rapidly on inactivation of large T, consistent with p53 involvement. This medium‐induced decrease in cell survival could not be rescued by the ICE inhibitor but was partially rescued by BCL‐2 or BCL‐XL. Furthermore, studies involving expression of BCL‐2 and BCL‐XL alone or together revealed differences in the survival dependent on the cellular environment. These results suggest that apoptosis of neuronal cellsoccurs by at least two processes: one in undifferentiated cells initiated by removal of serum and one linked to differentiation. The data implicate the ICE enzyme family but not p53 in apoptosis induced by differentiation and demonstrate that either BCL‐2 or BCL‐XL can prolong the survival of differentiated neuronal cells.
Reverse stochastic resonance in a hippocampal CA1 neuron model

Stochastic resonance (SR) is a ubiquitous and counter- intuitive phenomenon whereby the addition of noise to a non-linear system can improve the detection of sub-threshold signals. The “signal” is normally periodic or deterministic whereas the “noise” is normally stochastic. However, in neural systems, signals are often stochastic. Moreover, periodic signals are applied near neurons to control neural excitability (i.e. deep brain stimulation). We therefore tested the hypothesis that a quasi-periodic signal applied to a neural network could enhance the detection of a stochastic neural signal (reverse stochastic resonance). Using computational methods, a CA1 hippocampal neuron was simulated and a Poisson distributed subthreshold synaptic input (“signal”) was applied to the synaptic terminals. A periodic or quasi periodic pulse train at various frequencies (“noise”) was applied to an extracellular electrode located near the neuron. The mutual information and information transfer rate between the output and input of the neuron were calculated. The results display the signature of stochastic resonance with information transfer reaching a maximum value for increasing power (or frequency) of the “noise”. This result shows that periodic signals applied extracellularly can improve the detection of subthreshold stochastic neural signals. The optimum frequency (110Hz) is similar to that used in patients with Parkinson's suggesting that this phenomenon could play a role in the therapeutic effect of high frequency stimulation.
LIS Working Paper Series Luxembourg Income Study ( LIS ) , asbl No . 587 Income Polarization and Economic Growth

This study examines empirically the impact of income polarization on economic growth in an unbalanced panel of more than 70 countries during the 1960–2005 period. We calculate various polarization indices using existing micro-level datasets, as well as datasets reconstructed from grouped data on income distribution taken from the World Income Inequality Database. The results garnered for our preferred sample of countries suggest that income polarization has a negative impact on growth in the short term, while the impact of income inequality on growth is statistically insignificant. Our results are fairly robust to various model specifications and estimation techniques. JEL classification codes: O11, O15, O4, D31
The impact of individual and shared employee perceptions of HRM on affective commitment: Considering climate strength

Purpose – The purpose of this paper is to answer the question of whether individual perceptions of an HRM system – distinctiveness, consistency and consensus – and shared perceptions of HRM (climate strength) are positively related to affective commitment in the organization. In addition, the paper examines if climate strength has a mediating effect in the relationship between the individual perceptions of an HRM system and affective commitment.Design/methodology/approach – A survey study with data from 671 employees, 67 line‐managers and 32 HR‐managers within four hospitals was used.Findings – Results of two‐level analyses (department, employee) showed that the perception of distinctiveness, consistency and climate strength, as expected are positively related to affective commitment. Instead of a mediating effect of climate strength a moderator effect was found: the relationship between consistency and affective commitment is stronger when climate strength is high.Research limitations/implications – The .
Pressures on Audit Partner’s Negotiation Strategy and Decision Making Christopher Koch PhD Professor of Corporate Governance

In our experiment with highly experienced auditors, we manipulate, as well as measure, different pressures on auditors from client management and the audit firm’s management control systems (MCS). We investigate their effects on auditor decision making about the acceptability of aggressive client preferred accounting and on the strategies the auditor would employ in negotiating that accounting with client management. We find that auditors generally resist relatively more explicit client pressure, but we also find that auditors are more likely to agree to such aggressive accounting when client pressure is subtle or when the auditor is reminded of the audit firm’s use of customer relationship management (CRM) tools (e.g. having client management assess audit team service quality) as part of the audit firm’s MCS. These findings imply that client management, if subtle, can pressure auditors into accepting the accounting management wants. Further, audit firms can act as enablers for such pressure through use of CRM tools that are not designed for professional services with explicit conflicts of interests between the service provider and the purchaser of the service.
Rapid diagnosis of methicillin-resistant Staphylococcus aureus bacteremia by nested polymerase chain reaction.

OBJECTIVE The purpose of this study was to establish a rapid and sensitive diagnostic method for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia in postoperative patients. SUMMARY BACKGROUND DATA As a result of diffusion and abuse of third-generation cephalosporin antibiotics in the 1980s in Japan, an outbreak of MRSA infection has been posed. In the field of surgery, severe postoperative infections with MRSA such as MRSA bacteremia, which may lead to multiple organ failure, have emerged with a high mortality. METHODS Thirty-five patients with high fever (above 38.5 C) or watery diarrhea or both within 2 weeks after gastrointestinal major surgery and 6 healthy volunteers were examined. Nested polymerase chain reaction was used to detect mecA and toxic shock syndrome toxin-1 (TSST-1) genes in blood specimens. RESULTS The mecA and TSST-1 genes were not detected in the blood samples of any of the six healthy volunteers. In all 12 samples from which MRSA colonies were isolated by blood culture, mecA and TSST-1 genes were detected. Although it took at least 48 hours to identify MRSA by the blood culture method, the presence of mecA and TSST-1 genes was determined by nested polymerase chain reaction method within only 3 to 4 hours after blood sampling. CONCLUSIONS This method, as a sensitive and rapid monitoring system for MRS bacteremia, would be clinically beneficial for prevention of cross infection and for early determination of appropriate treatment for infected patients.
Comparison of the efficacy of three concentrations of retinoic acid for transdifferentiation induction in sheep marrow‐derived mesenchymal stem cells into male germ cells

Recent studies have shown the unique role of retinoic acid (RA) in the induction of transdifferentiation in mesenchymal stem cells (MSCs) into germ cells (GCs). This study is the first study that compares the efficacy of three different concentrations of RA for the production of male GCs in vitro. Male sheep marrow‐derived MSCs (MMSCs) were treated with the following concentrations of RA: 1 μm (RA1), 5 μm (RA2) and 10 μm (RA3) for a period of 21 days. The production of male GCs was evaluated by the assessment of expressions of GC‐specific markers (by RT‐PCR, qRT‐PCR and immunocytochemistry), morphological characteristics and changes in alkaline phosphatase (ALP) activity. All three concentrations created male GC features. RA treatment upregulated the expressions of VASA and beta1 INTEGRIN and downregulated PIWIL2 and OCT4. DAZL was not expressed by RA treatment. Interestingly, immunocytochemistry detected PGP 9.5 expression in all treatment groups, with the highest expression noted in the RA3 group (P < 0.05). GC‐like cells along with increased ALP activity were observed in all treated cultures, too. Finally, results showed that 10 μm RA has the most efficiency for transdifferentiation induction in MMSCs and production of male GCs in vitro.
Orphan receptor tyrosine kinases ROR1 and ROR2 in hematological malignancies

Abstract The receptor tyrosine kinase ROR1 has been shown to be overexpressed in chronic lymphocytic leukemia (CLL). The aim of this study was to further characterize the expression of ROR1 and the other member of the ROR family, ROR2, in other lymphoid and myeloid malignancies. Normal white blood cells and reactive lymph nodes were negative for ROR1 and ROR2. A significantly high and uniform surface expression of ROR1 was found in CLL/hairy cell leukemia (HCL) compared to mantle cell lymphoma (MCL), marginal zone lymphoma (MZL), diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), myelomas, acute lymphoblastic leukemia (ALL) and myeloid leukemias (p = 0.02 to < 0.001). The lowest proportion of ROR1+ cells was seen in FL, whereas CLL, HCL and CML had significantly higher numbers of ROR1+ cells. Longitudinal follow-up of individual patients with CLL revealed that ROR1+ cells remained stable over time in non-progressive patients, but increased when the disease progressed (p < 0.05). Thus, a variable staining pattern of ROR1 ranging from very high (CLL, HCL) and high (CML) to intermediate (myeloma and DLBCL) or low (FL) was noted. ROR2 was not detected in hematological malignancies.
Data Management and Layout for Shingled Magnetic Recording

Ultimately the performance and success of a shingled write disk (SWD) will be determined by more than the physical hardware realized, but will depend on the data layouts employed, the workloads experienced, and the architecture of the overall system, including the level of interfaces provided by the devices to higher levels of system software. While we discuss several alternative layouts for use with SWD, we also discuss the dramatic implications of observed workloads. Example data access traces demonstrate the surprising stability of written device blocks, with a small fraction requiring multiple updates (the problematic operation for a shingled-write device). Specifically, we discuss how general purpose workloads can show that more than 93% of device blocks can remain unchanged over a day, and that for more specialized workloads less than 0.5% of a shingled-write disk's capacity would be needed to hold randomly updated blocks. We further demonstrate how different approaches to data layout can alternatively improve or reduce the performance of a shingled-write device in comparison to the performance of a traditional non-shingled device.
Phospho3D 2.0: an enhanced database of three-dimensional structures of phosphorylation sites

Phospho3D is a database of three-dimensional (3D) structures of phosphorylation sites (P-sites) derived from the Phospho.ELM database, which also collects information on the residues surrounding the P-site in space (3D zones). The database also provides the results of a large-scale structural comparison of the 3D zones versus a representative dataset of structures, thus associating to each P-site a number of structurally similar sites. The new version of Phospho3D presents an 11-fold increase in the number of 3D sites and incorporates several additional features, including new structural descriptors, the possibility of selecting non-redundant sets of 3D structures and the availability for download of non-redundant sets of structurally annotated P-sites. Moreover, it features P3Dscan, a new functionality that allows the user to submit a protein structure and scan it against the 3D zones collected in the Phospho3D database. Phospho3D version 2.0 is available at: http://www.phospho3d. org/.