Miracle-dz/UniFAR-FTUs huggingface dataset:
Sequencing in Media Dialogical Networks

In this paper we investigate the dialogicity of media texts, one of their characteristics which is often neglected. Lena Jayussi in fact asserted some time ago that “one of the salient features of media texts is that they are addressed, not to a specific person or sets of persons with known properties, relevancies and beliefs, but rather to a ‘public at large’ which could include a general distribution of professional affiliations, political and religious beliefs, skills and ‘knowledge’ of substantive matters, interests, and experiences. ” She continued “a second salient feature of media texts is that they are not dialogic: responses, problems, corrections, clarifications cannot be produced spatiotemporally to coincide with the text or with each other as in an ordinary conversation. ” (Jayussi, 1991). Spatiotemporally contingent responses to media texts may indeed not be typically possible, but this does not mean that media texts are not dialogical. We want to show here that there indeed are some features of media texts which could be characterised as dialogic. This we expressed previously in our concept of “dialogical network” (Leudar, 1995; Leudar, 1998; Nekvapil and Leudar 1998; Leudar and Nekvapil, 1998; Nekvapil and Leudar, 2002a; Nekvapil and Leudar, 2002b).
Calcein assay for multidrug resistance reliably predicts therapy response and survival rate in acute myeloid leukaemia

In this study, we evaluated the suitability of the calcein assay as a routine clinical laboratory method for the identification of multidrug‐resistant phenotype in acute leukaemia. This study presents the results of the calcein tests obtained in two large haematological centres in Hungary. Assays were performed with blast cells of 93 de novo acute leukaemia patients, including 65 patients with acute myeloid leukaemia (AML). Results were expressed as multidrug resistance activity factor (MAF) values. AML patients were divided into responders and non‐responders and MAF values were calculated for each group. In both centres, responder patients displayed significantly lower MAF values than non‐responders (P = 0·0045 and P = 0·0454). Cut‐off values were established between the MAFR + SEM and MAFNR − SEM values. On the basis of these cut‐off levels, multidrug resistance (MDR) negativity showed a 72% predictive value for the response to chemotherapy, whereas MDR positivity was found to have an average predictive value of 69% for therapy failure. MDR activity was a prognostic factor for survival rate and the test was suitable for detecting patients at relapse. The calcein assay can be used as a quantitative, standardized, inexpensive screening test in a routine clinical laboratory setting. The assay detects both P‐glycoprotein and multidrug resistance‐associated protein activities, and identifies AML patients with unfavourable therapy responses.
Robot programming

The industrial robot's principal advantage over traditional automation is programmability. Robots can perform arbitrary sequences of pre-stored motions or of motions computed as functions of sensory input. This paper reviews requirements for and developments in robot programming systems. The key requirements for robot programming systems examined in the paper are in the areas of sensing, world modeling, motion specification, flow of control, and programming support. Existing and proposed robot programming systems fall into three broad categories: guiding systems in which the user leads a robot through the motions to be performed, robot-level programming systems in which the user writes a computer program specifying motion and sensing, and task-level programming systems in which the user specifies operations by their desired effect on objects. A representative sample of systems in each of these categories is surveyed in the paper.
Semantic Categorization of Placement Verbs in L1 and L2 Danish and Spanish.

This study investigates sematic categorization of the meaning of placement verbs by Danish and Spanish native speakers and two groups of intermediate second language (L2) learners (Danish learners of L2 Spanish and Spanish learners of L2 Danish). Participants described 31 video clips picturing different types of placement events. Cluster analyses revealed considerable differences in the semantic categorization of these events in Danish and Spanish as well as learning difficulties for the two learner groups. When Danish and Spanish differ in the number and nature of semantic distinctions, L2 verb meaning reconstruction becomes challenging when moving from a more to a less complex system and vice versa. Both learner groups used noncaused motion verbs, overgeneralized given placement verbs, and tended to use L2 verbs haphazardly.
PERPETUITIES WITH THIN TAILS REVISITED

We consider the tail behavior of random variables $R$ which are solutions of the distributional equation $R\stackrel{d}{=}Q+MR$, where $(Q,M)$ is independent of $R$ and $|M|\le 1$. Goldie and Gr\"{u}bel showed that the tails of $R$ are no heavier than exponential and that if $Q$ is bounded and $M$ resembles near 1 the uniform distribution, then the tails of $R$ are Poissonian. In this paper, we further investigate the connection between the tails of $R$ and the behavior of $M$ near 1. We focus on the special case when $Q$ is constant and $M$ is nonnegative.
Pod Corn Is Caused by Rearrangement at the Tunicate1 Locus[W][OA]

Pod corn (Zea mays), once considered as ancestral to cultivated maize, has a striking phenotype in which each kernel is enclosed with chaff. This phenotype is explained by a chromosomal rearrangement at the Tunicate1 (Tu1) locus that alters the expression pattern of the Tu1 MADS box gene involved in determining floral organ identity. Pod corn (Zea mays var tunicata) was once regarded as ancestral to cultivated maize, and was prized by pre-Columbian cultures for its magical properties. Tunicate1 (Tu1) is a dominant pod corn mutation in which kernels are completely enclosed in leaflike glumes. Here we show that Tu1 encodes a MADS box transcription factor expressed in leaves whose 5′ regulatory region is fused by a 1.8-Mb chromosomal inversion to the 3′ region of a gene expressed in the inflorescence. Both genes are further duplicated, accounting for classical derivative alleles isolated by recombination, and Tu1 transgenes interact with these derivative alleles in a dose-dependent manner. In young ear primordia, TU1 proteins are nuclearly localized in specific cells at the base of spikelet pair meristems. Tu1 branch determination defects resemble those in ramosa mutants, which encode regulatory proteins expressed in these same cells, accounting for synergism in double mutants discovered almost 100 years ago. The Tu1 rearrangement is not found in ancestral teosinte and arose after domestication of maize.
Metabolic and proteomic adaptation of Lactobacillus rhamnosus strains during growth under cheese‐like environmental conditions compared to de Man, Rogosa, and Sharpe medium

The aim of this study was to demonstrate the metabolic and proteomic adaptation of Lactobacillus rhamnosus strains, which were isolated at different stages of Parmigiano Reggiano cheese ripening. Compared to de Man, Rogosa, and Sharpe (MRS) broth, cultivation under cheese‐like conditions (cheese broth, CB) increased the number of free amino acids used as carbon sources. Compared with growth on MRS or pasteurized and microfiltrated milk, all strains cultivated in CB showed a low synthesis of d,l‐lactic acid and elevated levels of acetic acid. The proteomic maps of the five representative strains, showing different metabolic traits, were comparatively determined after growth on MRS and CB media. The amount of intracellular and cell‐associated proteins was affected by culture conditions and diversity between strains, depending on their time of isolation. Protein spots showing decreased (62 spots) or increased (59 spot) amounts during growth on CB were identified using MALDI‐TOF‐MS/MS or LC‐nano‐ESI‐MS/MS. Compared with cultivation on MRS broth, the L. rhamnosus strains cultivated under cheese‐like conditions had modified amounts of some proteins responsible for protein biosynthesis, nucleotide, and carbohydrate metabolisms, the glycolysis pathway, proteolytic activity, cell wall, and exopolysaccharide biosynthesis, cell regulation, amino acid, and citrate metabolism, oxidation/reduction processes, and stress responses.
Clustering method for fast deformation with constraints

We present a fast deformation method for flexible objects. The deformation of the object is physically modeled using a linear elasticity model with a displacement based finite elements method, yielding a linear system at each time step of simulation. We solve this linear system using a precomputed force-displacement matrix, which describes the object response in terms of displacement accelerations to the forces acting on each vertex. We exploit the spatial coherence to effectively compress the force-displacement matrix to make this method practical and efficient by applying the clustered principal component analysis method. And we developed a method to efficiently handle the additional constraints for interactive user manipulation. At last large deformations are addressed based upon the compressed force-displacement matrix by combining a domain decomposition method and tracking the rotational motions. The experimental results demonstrate fast performances on complex large scale objects under interactive user manipulations.
Image Micro-pattern Analysis Using Fuzzy Numbers

This paper proposes a new methodology for micro pattern analysis in digital images based on fuzzy numbers. A micro-pattern is the structure of the gray-level pixels within a neighborhood and can describe the spatial context of the image, such as edge, line, spot, blob, corner, texture, and more complex patterns. By treating a pixel neighborhood as a fuzzy set and each pixel gray-level as a fuzzy number, we can evaluate the membership degree of the central pixel to the others. We have called this method the Local Fuzzy Pattern (LFP). Using a sigmoid membership function, we proved that the proposed methodology surpasses the Hit-rate of the Local Binary Pattern (LBP), for texture classification. The LFP proved to be robust to image rotation. Moreover, our proposed formulation for the LFP is a generalization of previously published techniques, such as Texture Unit, LBP, FUNED, and Census Transform.
Testing flow graph reducibility

Many problems in program optimization have been solved by applying a technique called interval analysis to the flow graph of the program. A flow graph which is susceptible to this type of analysis is called reducible. This paper describes an algorithm for testing whether a flow graph is reducible. The algorithm uses depth-first search to reveal the structure of the flow graph and a good method for computing disjoint set unions to determine reducibility from the search information. When the algorithm is implemented on a random access computer, it requires O(E log* E) time to analyze a graph with E edges, where log* x = min{i/logix≤1}. The time bound compares favorably with the O(E log E) bound of a previously known algorithm.
Canonical heights and entropy in arithmetic dynamics

A system of transformations is associated to a rational point on an elliptic curve. The sequence entropy is connected to the canonical height, and in some cases there is a canonically defined quotient system whose entropy is the canonical height and for which the fibre entropy is accounted for by local heights at primes of bad reduction. The proofs use transcendence theory and a strong form of Siegel's theorem. We go on to extend these ideas to the morphic heights of Call and Goldstine.
Knowledge Retrieval and the World Wide Web

L ARGE-SCALE WEB SEARCH engines effectively retrieve entire documents, but they are imprecise, because they do not exploit and hence retrieve the semantic Web document content. We cannot automatically extract such content from general documents yet. Manually structuring Web documents— for example, with XML—lets us retrieve more precise information using stringand structure-matching tools, such as the Web robots Harvest, WebSQL, and WebLog. However, this approach is not scalable, because it only retrieves fine-grained information if the documents are thinly structured and the querier knows their structures, exact names, and forms. Knowledge representation languages that support logic inference can help us achieve more flexible and precise knowledge representation and retrieval. Industry is currently developing many metadata languages to let people index Web information resources with knowledge representations (logical statements) and store them in Web documents. However, these metadata languages are insufficient to satisfy several requirements necessary to allow precise, flexible, and scalable information retrieval. On the basis of ease and representational completeness, we argue in favor of general and intuitive knowledge representation languages such as conceptual graphs (CGs) 1 rather than the direct use of XML-based languages. To let users represent knowledge at the level of detail they require, we propose simple notations for restricted knowledge representation cases and a technique that lets users leave knowledge terms undeclared. We built a Web-accessible tool (CGI server), WebKB, 2,3 to support this approach and let its users combine lexical, s ructural, and knowledge-based techniques to exploit or generate Web documents. WebKB is an ontology server and directed Web robot. (See the sidebar for a list of related URLs.)
Accuracy of cytological grading of spindle‐cell sarcomas

Spindle‐cell sarcomas constitute an important component of soft‐tissue sarcomas, where accurate grading may be more important than histologic subtype in order to plan treatment strategies and determine prognosis. To evaluate the applicability and accuracy of grading spindle‐cell sarcomas on fine‐needle aspiration cytology (FNAC) smears, 54 cases of histologically documented spindle‐cell sarcomas, consisting of synovial sarcomas (20 cases), neurofibrosarcomas (12 cases), leiomyosarcomas (9 cases), dermatofibrosarcoma protuberans (DFSP; 6 cases), fibrosarcomas (3 cases), hemangiopericytomas (2 cases), and spindle‐cell sarcomas, unclassified (2 cases), were graded according to a three‐tier system proposed earlier for FNAC smears, while the histological sections were graded using the French Federation of National Cancer Centers (FNCLCC) grading system. The cytological grading was correlated with the histological grade. There was an overall cytologic and histologic concordance in 40/54 (74%) cases, and concordance in 9/13 (69%) grade I, 19/25 (76%) grade II, and 12/16 (75%) grade III cases. Analysis of grading of individual sarcomas revealed a concordance in 92% of neurofibrosarcomas, 78% of leiomyosarcomas, 70% of synovial sarcomas, 67% of dermatofibrosarcoma protuberans, 67% of fibrosarcomas, 50% of hemangiopericytomas, and 50% of cases of malignant mesenchymal tumors, spindle‐cell type unclassified. Major noncorrelation was seen in 10/54 (18.5%) cases. Minor noncorrelation was seen in 4/54 (7.4%) cases. Thus it is possible to accurately predict the grade in 74% of cases of spindle‐cell sarcomas. The cytological and histological concordance was better (75%) in high‐grade (grades II and III) as compared to grade I sarcomas (69%). Sampling errors due to morphologic heterogeneity in sarcomas may cause noncorrelation in a few cases. Diagn. Cytopathol. 2003;29:79–83. © 2003 Wiley‐Liss, Inc.
Prenatal ethanol increases ethanol intake throughout adolescence, alters ethanol‐mediated aversive learning, and affects μ but not δ or κ opioid receptor mRNA expression

Animal models of prenatal ethanol exposure (PEE) have indicated a facilitatory effect of PEE on adolescent ethanol intake, but few studies have assessed the effects of moderate PEE throughout adolescence. The mechanisms underlying this facilitatory effect remain largely unknown. In the present study, we analysed ethanol intake in male and female Wistar rats with or without PEE (2.0 g/kg, gestational days 17–20) from postnatal days 37 to 62. The results revealed greater ethanol consumption in PEE rats than in controls, which persisted throughout adolescence. By the end of testing, ethanol ingestion in PEE rats was nearly 6.0 g/kg. PEE was associated with insensitivity to ethanol‐induced aversion. PEE and control rats were further analysed for levels of μ, δ and κ opioid receptor mRNA in the infralimbic cortex, nucleus accumbens shell, and ventral tegmental area. Similar levels of mRNA were observed across most areas and opioid receptors, but μ receptor mRNA in the ventral tegmental area was significantly increased by PEE. Unlike previous studies that assessed the effects of PEE on ethanol intake close to birth, or in only a few sessions during adolescence, the present study observed a facilitatory effect of PEE that lasted throughout adolescence. PEE was associated with insensitivity to the aversive effect of ethanol, and increased levels of μ opioid receptor transcripts. PEE is a prominent vulnerability factor that probably favors the engagement of adolescents in risky trajectories of ethanol use.
Relationships between family communication and consumer activities of adolescents: An exploratory study

This study uses a multitrait, multi-informant approach to examine the relationships between family communication and adolescent involvement in consumer activity using two measures of family communication, one that measures the general quality of communication between parents and adolescents, and another that measures the frequency of consumption-specific communication between parents and adolescents. In addition, the perceptions of mothers, fathers, and adolescents are used in the analysis. Findings show that the two communication constructs are conceptually distinct. Positive relationships between the communication constructs and adolescents’ consumer activities are found; however, the presence of significant relationships depends on which individual family members’ or family member dyads’ perceptions are used in the analysis. On the basis of the findings, several suggestions for future research are discussed.
Automatic organisation of retrieved images into a hierarchy

Image retrieval is of growing interest to both search engines and academic researchers with increased focus on both content-based and caption-based approaches. Image search, however, is different from document retrieval: users often search a broader set of retrieved images than they would examine returned web pages in a search engine. In this paper, we focus on a concept hierarchy generation approach developed by Sanderson and Croft in 1999, which was used to organise retrieved images in a hierarchy automatically generated from image captions. Thirty participants were recruited for the study. Each of them conducted two different kinds of searching tasks within the system. Results indicated that the user retrieval performance in both interfaces of system is similar. However, the majority of users preferred to use the concept hierarchy to complete their searching tasks and they were satisfied with using the hierarchical menu to organize retrieved results, because the menu appeared to provide a useful summary to help users look through the image results.
Colonization of Lutzomyia verrucarum and Lutzomyia longipalpis Sand Flies (Diptera: Psychodidae) by Bartonella bacilliformis, the Etiologic Agent of Carrión’s Disease

Bartonella bacilliformis is a pathogenic bacterium transmitted to humans presumably by bites of phlebotomine sand flies, infection with which results in a bi-phasic syndrome termed Carrión’s disease. After constructing a low-passage GFP-labeled strain of B. bacilliformis, we artificially infected Lutzomyia verrucarum and L. longipalpis populations, and subsequently monitored colonization of sand flies by fluorescence microscopy. Initially, colonization of the two fly species was indistinguishable, with bacteria exhibiting a high degree of motility, yet still confined to the abdominal midgut. After 48h, B. bacilliformis transitioned from bacillus-shape to a non-motile, small coccoid form and appeared to be digested along with the blood meal in both fly species. Differences in colonization patterns became evident at 72h when B. bacilliformis was observed at relatively high density outside the peritrophic membrane in the lumen of the midgut in L. verrucarum, but colonization of L. longipalpis was limited to the blood meal within the intra-peritrophic space of the abdominal midgut, and the majority of bacteria were digested along with the blood meal by day 7. The viability of B. bacilliformis in L. longipalpis was assessed by artificially infecting, homogenizing, and plating for determination of colony-forming units in individual flies over a 13-d time course. Bacteria remained viable at relatively high density for approximately seven days, suggesting that L. longipalpis could potentially serve as a vector. The capacity of L. longipalpis to transmit viable B. bacilliformis from infected to uninfected meals was analyzed via interrupted feeds. No viable bacteria were retrieved from uninfected blood meals in these experiments. This study provides significant information toward understanding colonization of sand flies by B. bacilliformis and also demonstrates the utility of L. longipalpis as a user-friendly, live-vector model system for studying this severely neglected tropical disease.
Preserving biosensor users' anonymity over wireless cellular network

A wireless body sensor network takes a significant part in mobile E-healthcare monitoring service. Major concerns for patient's sensitive information are related to secure data transmission and preserving anonymity. So far, most researchers have only focused on security or privacy issues related to wireless body area network (WBAN) without considering all the communication vulnerabilities. However, since bio data sensed by biosensors travel over both WBAN and the cellular network, it is required to study about a privacy-enhanced scheme that covers all the secure communications. In this paper, we first point out the weaknesses of previous work in [9]. Then, we propose a novel privacy-enhanced E-healthcare monitoring scheme in wireless cellular network. Our proposed scheme provides anonymous communication between a patient and a doctor in a wireless cellular network satisfying security requirements.
A P7 Phage-Like Plasmid Carrying mcr-1 in an ST15 Klebsiella pneumoniae Clinical Isolate

A Klebsiella pneumoniae clinical strain, named SCKP83, was isolated and found to be resistant to colistin thanks to the presence plasmid-borne colistin resistant gene mcr-1. The strain was subjected to whole genome sequencing and conjugation experiments. The subsequent analysis indicated that the strain belongs to ST15 and the capsular type K41. In SCKP83, mcr-1 was carried by a 97.4-kb non-self-transmissible plasmid, a 90.9-kb region of which was predicted as an intact phage. This phage was 47.79% GC content, encoded 105 proteins and contained three tRNAs. mcr-1 was located downstream of two copies of the insertion sequence ISApl1 (one complete and one truncated) and was inserted in the ant1 gene, which encodes a putative antirepressor for antagonizing C1 repression, in this phage. The phage is highly similar to phage P7 (77% coverage and 98% identity) from Escherichia coli. Several similar mcr-1-carrying plasmids have been found in E. coli at various locations in China, suggesting that these phage-like plasmids have circulated in China. The findings in this study suggest that the P7 phage-like plasmids are not restricted to E. coli and may represent new vehicles to mediate the inter-species spread of mcr-1.