Miracle-dz/UniFAR-FTUs huggingface dataset:
Studies on the hexapod nervous system. III. Histology and histochemistry of cockroach neuroglia

A growing interest in the neuroglial elements of the vertebrate nervous system is evidenced by a steadily accumulating literature, and by the appearance of two recent monographs (Glees, '55; Windle, '58). These efforts are justified by the supposition that neuroglia and its equivalent in the peripheral nervous system (satellite and Schwann cells) execute a role in the economy of nervous tissue which is considerably more dynamic than that of mechanical support. Thus, these non-nervous elements are presumed to participate in the formation and maintenance of myelin, in nerve regeneration, in the functioning of the blood-brain barrier, and probably in electrophysiological phenomena related to nervous activity. Relatively little is known about the structure of invertebrate neuroglia; still less about its histochemistry. As a consequence those unifying concepts so frequently provided by the comparative approach are lacking. An understanding of the structure of invertebrate neuroglia is also important in its own right, constituting a prerequisite to investigations of its functional significance. The present study on certain features of insect glia is a contribution toward this end.
Reducing Phase Noise in Multi-Phase Oscillators

This paper investigates phase noise mechanism in arrays of resonant LC oscillators. Such arrays represent today a promising solution for the generation of multi-phase signals needed in several advanced applications. The analysis presented in this paper relies on consolidated phase-domain macromodels as well as on the original concept of noise transfer function illustrated herein. The proposed analysis sheds new light on noise generation in oscillator arrays and is able to explain certain noise degradation effects observed in nonreciprocal coupling networks. Phase-domain simulation together with noise transfer function concept provide a very efficient computational tool for rapid calculations of phase response and output noise. Thanks to this efficient tool and to the gained qualitative understanding, we are able to propose a chain array configuration enhanced by the injection of a clean, low-noise signal. In this paper, it is shown how the injected chain array can provide the prescribed phase separation while significantly reducing output phase noise.
Effects of post-hatch nutrition of arginine, lysine, methionine and threonine on performance and intestinal morphology in broiler chickens.

1 Department of Clinical Sciences, Faculty of Veterinary Medicine, Islamic Azad University, Garmsar Branch, Garmsar, Iran; 2 Department of Basic Sciences (Physiology division), Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran; 3 Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran; 4 Department of Clinical Science, Faculty of Veterinary Medicine, Tehran University, Tehran, Iran
Crash me if you can: Rethinking sustainable Data Center Networking from a topological perspective

a data center is a pool of resources such as computational, storage facilities, and servers interconnected using a communications network. The Data Center Networking (DCN) holds a pivotal role, and it needs to be scalable and efficient to connect the growing number of servers so as to handle the intensive demands in cloud computing. Recently there has been a rapidly growing literature on DCNs which focuses on studying how to model and evaluate the resource provisioning and allocation algorithms for more effective and efficient resource management of cloud systems. Unfortunately there is not much work to reveal how the underlying network topological connectivity can affect the overlay DCNs performance in aspects such as energy consumption and service resilience. There is a saying that, it is not what you know i.e., the algorithm itself but who you know i.e., connectivity, which argues that people get ahead in life based on their connections, not on their skills or knowledge, and every day offers evidence of this aphorism. This case also applies to DCNs. DCNs performance is not merely a function of resource provisioning and allocation, but also it is a network-wide activity. The structure and ties that links a data center to other data centers are also critical factors. In this paper, we are paving a new developing line of research on revealing the roles of network topological characteristics to foster more sustainable DCNs in terms of resource efficiency and service resilience. We believe this research is thought-provoking, and opens a new conversation for researchers working in the area of sustainable DCNs communications and networking.
The Strengths and Difficulties Questionnaire (SDQ-Fin) among Finnish children and adolescents

Merja Koskelainen The Strengths and Difficulties Questionnaire (SDQ-Fin) among Finnish children and adolescents Department of Child Psychiatry, University of Turku, Turku, Finland Objective: The psychometric properties of The Strengths and Difficulties Questionnaire (SDQ-Fin), a Finnish version of a brief screening instrument were studied. Emotional and behavioural problems of 7to 15-year-olds measured by the SDQ were reported, as well as the occurrence of self-reported eating disturbance symptoms and alcohol use among adolescents. Methods and samples: The cross-sectional school survey included 25 items of the SDQ-Fin, items about eating disturbance, alchol use and child psychiatric help-seeking. The study consists of three community samples: 1. The SDQ-Fin parent (n = 703) and teacher (n = 376) versions of 7 – 12 –year-olds, and self-report versions (n = 528) of 11 – 16 years-olds were obtained, and 2. the parent (n = 81) and self-report versions of 15-16 –year olds (n = 129) were obtained in Laitila and Pyhäranta. 3. The self-report versions of 13 – 16 – year-olds (n = 1458) in Salo and Rovaniemi were obtained. Results: The psychometric properties of the SDQ-Fin were for the most part comparable with the other European SDQ research results. The internal consistency (Cronbach’s alpha = 0.71 in all informants’ reports) and inter-rater reliability (between the pairs of reports r = 0.38 0.44) were adequate. The concurrent validity (r = 0.75 between the SDQ and the CBCL total scores; r = 0.71 between the SDQ and the YSR total scores) was sufficient. Factor analysis of the SDQ self-report generally confirmed the postulated structure for girls and boys, except for the conduct problems scale of boys, which was fused with emotional symptoms and with hyperactivity. The response rates, means and cut-off points of the SDQ self-report scores were similar to those found, e.g. in Norway and in Britain. A high level of psychological problems, especially emotional and conduct problems and hyperactivity-inattention, were associated with high level of eating disturbance symptoms and alcohol use. Conclusion: The results showed that the psychometric properties of the SDQ-Fin are adequate and provide additional confirmation of the usefulness of the SDQ-Fin for, e.g. screening, epidemiological research and clinical purposes.
QuickDB - Yet Another Database Management System?

Although DBMS (Database Management Systems) are of- ten hidden for a user, they are a part of many applications utilized in day-by-day life. In general, we can suppose two main types of DBMS: OLTP (On-Line Transaction Processing) and OLAP (On-Line Analytical Processing). We can also distinguish another classication related to the connection of a client and DBMS: client-server and embedded DBMS. The embedded DBMS enable to achieve the maximum performance since an often slow network connection is not used. As a result, they are uti- lized by in-memory computations where the maximum throughput is required. Although it seems that a lot of high quality DBMS exist and another DBMS are not required, there is not a system to meet all de- mands of the real world. In this paper, we introduce our prototype of embedded database system called QuickDB. We show that it includes a wide variety of data structures and it provides more ecient performance in many cases compared to up-to-date (embedded) DBMS.
Characterization of species and races of the genus meloidogyne by DNA restriction enzyme analysis.

Total DNA of three species of Meloidogyne spp. , including four subspecific races of M. incognita, were digested separately with EcoR I, Cla III, and Hind III and probed with (3)(2)P-labelled total genomic DNA from M. incognita race 1 in Southern hybridizations. Short exposures of Southern blots after Hind III digestion revealed patterns that were useful for separating the species. Race differences were seen after longer exposures. The DNA fragment patterns obtained were scanned with a laser densitometer and the data were subjected to principal coordinate and cluster analyses. The likelihood of cloning species and race-specific DNA probes is discussed.
Viewpoints in clinical proteomics: When will proteomics deliver clinically useful information?

Despite massive efforts, proteomics has not delivered biomarkers of clinical value. However, the technologies that are emerging today have the power to reach deep into proteomes and identify the patterns associated with different diseases. Study design is then crucial and sample quality, bioinformatics approaches, prevalidation, using independent patient cohort need to attract increased attention before proteomics will contribute to the needs of personalized medicine.
ALCOHOLISM TREATMENT FOR THE DEAF

During the past decade, alcoholism treatment services in the United States have experienced unprecedented growth. The federal and local governments and the general public have become increasingly aware of the devastating impact of alcohol abuse and alcoholism on people's health and welfare and on the overall economy. As a result of this growing awareness, diversified alcoholism services are now available in communities throughout the country. Despite this preponderance of treatment, there is at least one segment of the alcoholic population which has been virtually unserved. This is the deaf alcoholic. This paper will describe an innovative program of alcoholism treatment for the deaf.
Opinion Mining on the Web by Extracting Subject-Aspect-Evaluation Relations

This paper addresses the task of extracting opinions from a given document collection. Assuming that an opinion can be represented as a tuple 〈Subject, Aspect, Evaluation〉, we propose a computational method to extract such tuples from texts. In this method, the main task is decomposed into (a) the process of extracting Aspect-Evaluation pairs from a given text and (b) the process of judging whether an extracted pair expresses an opinion of the author. We apply machine-learning techniques to both subtasks. We also report on the results of our experiments and discuss future directions.
Treatment options for lysosomal storage disorders: developing insights

Introduction: Lysosomal storage disorders (LSDs) are clinically heterogeneous disorders that result primarily from lysosomal accumulation of macromolecules in various tissues. LSDs are always progressive, and often lead to severe symptoms and premature death. The identification of the underlying genetic and enzymatic defects has prompted the development of various treatment options. Areas covered: To describe the current treatment options for LSDs, the authors provide a focused overview of their pathophysiology. They discuss the current applications and challenges of enzyme-replacement therapy, stem-cell therapy, gene therapy, chaperone therapy and substrate-reduction therapy, as well as future therapeutic prospects. Expert opinion: Over recent decades, considerable progress has been made in the treatment of LSDs and in the outcome of patients. None of the current options are completely curative yet. They are complicated by the difficulty in efficiently targeting all affected tissues (particularly the central nervous system), in reaching sufficiently high enzyme levels in the target tissues, and by their high costs. The pathways leading from the genetic mutation to the clinical symptoms should be further elucidated, as they might prompt the development of new and ultimately curative therapies.
Anomalous event detection on large-scale GPS data from mobile phones using hidden markov model and cloud platform

Anomaly detection is an important issue in various research fields. An uncommon trajectory or gathering of people in a specific area might correspond to a special event such as a festival, traffic accident or natural disaster. In this paper, we aim to develop a system for detecting such anomalous events in grid-based areas. A framework based on a hidden Markov model is proposed to construct a pattern of spatio-temporal movement of people in each grid during each time period. The numbers of GPS points and unique users in each grid were used as features and evaluated. We also introduced the use of local score to improve the accuracy of the event detection. In addition, we utilized Hadoop, a cloud-computing platform, to accelerate the processing speed and allow the handling of large-scale data. We evaluated the system using a dataset of GPS trajectories of 1.5 million individual mobile phone users accumulated over a one-year period, which constitutes approximately 9.2 billion records.
The Chemical Accident Risk Assessment Thesaurus: A Tool for Analyzing and Comparing Diverse Risk Assessment Processes and Definitions

The Chemical Accident Risk Assessment Thesaurus (CARAT) is a database of the laws, regulations, guidance documents, and definitions of terms related to the risk assessment of accidental releases of chemicals from fixed installations. The database also contains information on the application of risk assessment methodologies to specific examples of potential chemical releases. The Organization for Economic Cooperation and Development urged the development of the Thesaurus to improve the communication among the member countries about the risk assessment of hazardous installations. The difficulty of communication is based in large part on the fact that certain “terms of art” have different meanings in different countries and cultures, or that different terms of art are used to address the same concept. The CARAT is designed to circumvent these difficulties, and is especially useful as a tool to analyze the definitions of terms related to risk assessment. Entries into the CARAT contain information from various international, national, and regional agencies that relate to risk assessment processes and definitions focused on accidental chemical releases. The entire system is accessible via the Internet. Retrieval of information from the CARAT is facilitated by five different searching tools: two of them are designed to search the CARAT for its entries. One facility is designed to search for laws and regulations, specific risk assessment cases (SRA), and risk assessment guidance documents (RAG) related to chemical accidents. The second search facility deals with entries of definitions. The design of the CARAT is ideally suited to capture the sense of definitions that are expressed as either a procedural definition (an “operation on a concept”) or a conceptual definitions (just the “concept”). A powerful third query tool is the “Comparison” facility. This query tool allows the user to compare the details CARAT entries of laws and regulations, SRA, RAG, or definitions, in any combination. The remaining two tools can perform searches by identifying entries that contain either certain combinations of hierarchical or descriptor details. Both types can be conducted in Boolean “and/or” mode.
Mesenchymal stem cell migration is regulated by fibronectin through α5β1-integrin-mediated activation of PDGFR-β and potentiation of growth factor signals

Cell migration during vascular remodelling is regulated by crosstalk between growth factor receptors and integrin receptors, which together coordinate cytoskeletal and motogenic changes. Here, we report extracellular matrix (ECM)-directed crosstalk between platelet-derived growth factor receptor (PDGFR)-β and α5β1-integrin, which controls the migration of mesenchymal stem (stromal) cells (MSCs). Cell adhesion to fibronectin induced α5β1-integrin-dependent phosphorylation of PDGFR-β in the absence of growth factor stimulation. Phosphorylated PDGFR-β co-immunoprecipitated with α5-integrin and colocalised with α5β1-integrin in the transient tidemarks of focal adhesions. Adhesion to fibronectin also strongly potentiated PDGF-BB-induced PDGFR-β phosphorylation and focal adhesion kinase (FAK) activity, in an α5β1-integrin-dependent manner. PDGFR-β-induced phosphoinositide 3-kinase (PI3K) and Akt activity, actin reorganisation and cell migration were all regulated by fibronectin and α5β1-integrin. This synergistic relationship between α5β1-integrin and PDGFR-β is a fundamental determinant of cell migration. Thus, fibronectin-rich matrices can prime PDGFR-β to recruit mesenchymal cells at sites of vascular remodelling.
An Innovative Potential on Rule Optimization using Fuzzy Artificial Bee Colony

This study adapted an improved algorithm based on Artifical Bee Colony Optimization. It is not possible to justify that all the rules generated by fuzzy based apriori algorithm produce optimum result. Thus optimization of the result generated was carried out by Fuzzy Apriori algorithm using Fuzzy Artifical Bee Colony Optimization (FABCO), it's worth noting that a significant findings were revealed. FABCO is used for optimization of rules to get the best classification accuracy. The proposed method was compared with the traditional Artifical bee colony optimization and the particle swarm optimization. The current work proved a better classification performance compared to un-pruned rules.
Control of Canine Endoparasites, Especially Isospora spp., with Procox® in Naturally Infected Puppies: Parasitological, Bacteriological and Health Parameters

The effect of Procox? (Bayer, emodepside/toltrazuril suspension for dogs) against natural infections with Isospora spp. was investigated. Two groups were treated either with 0.5 ml suspension/kg of body weight (0.45 mg emodepside and 9 mg toltrazuril/kg of body weight) in the 3rd, 5th and 7th week of life (w.o.l.) (Procox? group; n = 28) or with a control anthelminthic (Dewormed Control group; n = 26). Animals were surveyed weekly from the 3rd w.o. l. by coproscopy and clinical examination. Faecal samples were examined microbiologically from the 4th to the 8th w.o. l. and faecal inflammatory markers canine calprotectin and canine S100A12 were measured in the 8th w.o. l. Specific antibody titres were evaluated in serum samples from five litters before and after vaccination against canine distemper virus and canine parvovirus 2. The prevalence of Isospora-positive animals increased to 67% in the Dewormed Control group (n = 15 puppies from four parasite-positive litters), while in the Procox? group (n = 15 puppies) it was less than 34% with significantly lower excretion (p ? was easily applied and effective; adverse effects did not occur. The level of seroconversion or titre increase upon vaccination was higher in parasite-free animals (91%) compared to Procox? -treated puppies (30%) and the Control animals (10%). Animals from parasite-free litters showed significantly different excretion patterns for haemolytic Escherichia coli and Clostridium perfringens, while there was no difference between Procox? -treated and Control animals. In some animals kept under poor hygienic conditions diarrhoea was noted in association with C. perfringens, E. coli or Salmonella. Concentrations of inflammatory markers in the faeces did not significantly differ between the Procox? and the Control group. Adequate control of parasitic and bacterial infections in suckling puppies requires both antiparasitic treatment and hygiene. Even when parasites do not cause overt effects treatment is recommended in cases with a history of parasite infections.
Applying Artificial Intelligence to Predict the Performance of Data-dependent Applications

Computational science (CS) is an emerging discipline that unites science and mathematics with disciplinary experience in biology, chemistry, physics, and other applied scientific fields. Within the scientific method, it is often referred to as the third science paradigm, complementing both theoretical and laboratory science (Miller & Boxer, 2005). In this work, CS involves the collaboration of the computing discipline, the mathematical support represented by the knowledge discovery process and by the models, and the computing parallel environment capability. Central to this computational science problem is the performance prediction of data-dependent applications, as shown on Figure 1. By the way, CS allows doing things that were previously too difficult to do due to the complexity of the mathematics, the large number of calculations involved, or a combination of both. Therefore, new challenges are continuously arising although CS is still at an early stage of development.
Performance analysis for multiuser dual-hop decode-and-forward cooperative system over Nakagami-m fading channels

Cooperative communication significantly increases the coverage area and enhances the system capacity with the help of relay nodes, whereas multiuser diversity is an important technology to improve spectral efficiency in multiuser system. In this paper, we study a multiuser dual-hop decode-and-forward (DF) cooperative system over Nakagami-m fading channels and derive some theoretical expressions for the system performance include average system capacity, outage capacity and symbol error probability (SEP). Our derived theoretical expressions provide an insight into the impact of multiuser diversity and Nakagami-m fading on the system performance.
Management of Subaxial Cervical Facet Dislocation Through Anterior Approach Monitored by Spinal Cord Evoked Potential

Study Design. Retrospective case series. Objective. To discuss the clinical efficacy of anterior cervical surgery of decompression, reduction, stabilization, and fusion in treating subaxial cervical facet dislocation without spinal cord injury or with mild spinal cord injury monitored by spinal cord evoked potential. Summary of Background Data. The optimal treatment of lower cervical facet dislocation has been controversial. Because of the risk of iatrogenic damage of neurological function, it is challenging for surgeons to manage the lower cervical facet dislocation without or with mild spinal cord injury. To avoid the risks, more secure strategy need to be designed. Methods. A retrospective study was performed on 17 cases of subaxial cervical facet dislocation without spinal cord injury or with mild spinal cord injury treated by anterior cervical surgery under spinal cord evoked potential monitor from January 2008 to June 2012. There were 12 males, 5 females, with a mean age of 40.1 years (from 21 to 73 yr). Dislocation sites: 1 in C3–C4, 2 in C4–C5, 6 in C5–C6, 8 in C6–C7; 10 cases with unilateral cervical facet dislocation, 7 cases with bilateral dislocation. Thirteen patients were preoperatively classified as grade D and 4 as E according to Frankel standard. All patients were followed up for average of 16 months. Results. All operations were completed successfully. Postoperative radiographs showed that the sequence and curvature of the cervical spine were well recovered. And, evidence of intervertebral fusion was observed at 3 months in all cases. No redislocation or symptoms of spinal cord injury occurred. Thirteen cases with mild spinal cord injury recovered at 1 month after operation. Conclusion. Anterior cervical surgery of decompression, reduction, stabilization, and fusion monitored by spinal cord evoked potential is an effective and safe method for treatment of subaxial cervical facet dislocation without or with mild spinal cord injury. Level of Evidence: 4