Miracle-dz/UniFAR-FTUs huggingface dataset:
An Improved Fast Search and Find of Density Peaks-Based Fog Node Location of Fog Computing System

As the most notably emerging wave of Internet deployments, Internet of Things (IoTs) requires mobility support, location awareness and low latency. Fog Computing, also termed edge computing, is a promising solution for IoTs by extending the Cloud Computing paradigm to the edge of Internet. But how to locate fog nodes' sites and determine the scale of each fog node is a main challenge of Fog Computing systems, especially for time sensitive Fog Computing systems. In this paper, we try to deal with this problem by proposing an improved Fast Search and Find of Density Peaks-based fog node location strategy to locate the fog nodes' sites and determine the resources for each located fog node. To this end, we firstly formulate the fog node location of Fog Computing systems as a clustering problem with multi-constraints. Then we propose an improved Fast Search and Find of Density Peaks-based fog node location algorithm, which introduces the time sensitive feature of IoT applications and improves the Fast Search and Find of Density Peaks clustering algorithm to make this clustering algorithm more robustness and adaptability. The experiment results show that our fog node location strategy not also can avoid the NP-hard problem of the traditional server placement strategies, but also has low time complexity.
Hybrid thin-ﬁlm solar cells based on nano-structured silicon and semiconducting polymer

This thesis presents an exploratory work on a new design of hybrid solar cells, which are based on a junction between an inorganic material (silicon) and a polymer (P3HT). This structure is intended to improve the efficiency of organic based solar cells while maintaining low costs. Here, we investigate its experimental feasibility, and we analyze its performance. The hetero-junction between silicon and P3HT has been studied on bilayer devices. We have shown that this junction generates electrical power under illumination, and that both silicon and P3HT can contribute to the photocurrent. Power conversion efficiencies up to 1.6 % have been obtained. A large amount of work has been done to simplify the fabrication process and to improve its reliability. Two new nano-structured silicon layers have been developed. ``Nano-sponge'' layers, where the typical dimensions of pores is 20 nm, have been obtained by metal-catalyzed plasma-enhanced CVD at 175 °C. Silicon nanowires have been grown by a completely new process: the substrates are transparent conductive oxides, the catalysts are generated in situ, and the growth temperature is below 300 °C. The wurtzite (Si-IV) phase has been identified in some wires, and various growth modes are observed. Both kinds of layers may also find applications in inorganic solar cells.
Disparities in Health Care Utilization and Functional Limitations Among Adults With Serious Psychological Distress, 2006-2014.

OBJECTIVE This study compared health care access, utilization, and functional indicators among adults with and without serious psychological distress (SPD) in the years surrounding implementation of the Patient Protection and Affordable Care Act (ACA). METHODS Adults ages 18 to 64 from the 2006-2014 National Health Interview Survey (N=207, 853) were examined on 11 access, utilization, and functional indicators: health insurance coverage (health coverage), insufficient money for medications, delay in health care (delay in care), insufficient money for health care, visiting a doctor ten or more times in the past 12 months, change in place of health care, change in place of health care due to insurance, limitations in ability to work, limitations in activities of daily living (ADLs), insufficient money for mental health care, and having seen a mental health care provider. RESULTS Multivariate models that were adjusted for health coverage and sociodemographic characteristics indicated that compared with adults without SPD, adults with SPD had greater odds of lacking money for medications (AOR=10.0) and health care (AOR=3.1), experiencing delays in care (AOR=2.7), visiting a doctor ten or more times in the past 12 months (AOR=3.2), changing usual place of health care (AOR=1.5), changing usual place of health care because of insurance (AOR=1.5), and experiencing limitations in ADLs (AOR=3.6) and ability to work (AOR=1.8). The proportions of adults with SPD who lacked health coverage and money to buy prescriptions increased during the study period. Although this trend reversed in 2014, the proportion with SPD experiencing barriers remained above 2006 levels. CONCLUSIONS Health care patterns among adults with SPD require greater attention.
Development and Validation of the Nursing Home Minimum Data Set 3.0 Mortality Risk Score (MRS3)

Background To develop a score to predict mortality using the Minimum Data Set 3.0 (MDS 3.0) that can be readily calculated from items collected during nursing home (NH) residents' admission assessments. Participants We developed a training cohort of Medicare beneficiaries newly admitted to United States NHs during 2012 (N = 1,426,815) and a testing cohort from 2013 (N = 1,160,964). Methods Data came from the MDS 3.0 assessments linked to the Medicare Beneficiary Summary File. Using the training dataset, we developed a composite MDS 3.0 Mortality Risk Score (MRS3) consisting of 17 clinical items and patients' age groups based on their relation to 30-day mortality. We assessed the calibration and discrimination of the MRS3 in predicting 30- and 60-day mortality and compared its performance to the Charlson Comorbidity Index and the clinician's assessment of 6-month prognosis measured at admission. Results The 30- and 60-day mortality rates for the testing population were 2.8% and 5.6%, respectively. Results from logistic regression models suggest that the MRS3 performed well in predicting death within 30 and 60 days (C-Statistics of 0.744 [95% confidence limit (CL) = 0.741, 0.747] and 0.709 [95% CL = 0.706, 0.711], respectively). The MRS3 was a superior predictor of mortality compared to the Charlson Comorbidity Index (C-statistics of 0.611 [95% CL = 0.607, 0.615] and 0.608 [95% CL = 0.605, 0.610]) and the clinicians' assessments of patients' 6-month prognoses (C-statistics of 0.543 [95% CL = 0.542, 0.545] and 0.528 [95% CL = 0.527, 0.529]). Conclusions The MRS3 is a good predictor of mortality and can be useful in guiding decision-making, informing plans of care, and adjusting for patients' risk of mortality.
Vaccine candidates against leishmania under current research

ABSTRACT Introduction: The search for vaccines to prevent human leishmaniasis is an active field of investigation aimed to prevent the devastating effects of this family of diseases on human health. The design and commercialization of several vaccines against canine leishmaniasis is a hopeful advance toward the achievement of a human vaccine. Areas covered: This review includes a summary of the most relevant immunological aspects accompanying leishmaniasis in natural hosts as well as a description of the latest advances in the multiple strategies that are being followed to develop leishmanial prophylactic vaccines. We have combined citations of the latest specialized reviews with research articles presenting the most recent results. Expert commentary: Achieving safe, effective, durable and low-cost prophylactic vaccines against leishmaniasis is still a major challenge. These vaccines should control not only parasite progression, but also the accompanying pathology, which results from an imbalanced interaction between the infectious agent and the human host immune system. Different strategies for development of vaccines are currently under investigation. They range from the use of live non-pathogenic vectors to the employment of subunit vaccines combined with adjuvants and/or delivery systems inducing cell-mediated immunity.
Elastic Behavior of Woven Fabric Composites: II—Laminate Analysis

Two-dimensional models are presented for the elastic analysis of the plain weave fabric laminates. A methodology to generate the laminate configuration from the lamina configuration is given. The effect of lamina configuration and their relative posi tions with respect to each other on the in-plane elastic constants of the woven fabric lami nates is studied. A laminate configuration with optimum shifts gives higher elastic proper ties compared to the other configurations. A comparison between in-plane elastic moduli of the unidirectionally laminated symmetric cross-ply laminates and plain weave fabric laminates is made. The in-plane elastic moduli of plain weave fabric laminates predicted by the models are found to be in good agreement with the experimental results.
The Impact of Early Social Interactions on Later Language Development in Spanish-English Bilingual Infants.

This study tested the impact of child-directed language input on language development in Spanish-English bilingual infants (N = 25, 11- and 14-month-olds from the Seattle metropolitan area), across languages and independently for each language, controlling for socioeconomic status. Language input was characterized by social interaction variables, defined in terms of speech style ("parentese" vs. standard speech) and social context (one-on-one vs. group). Correlations between parentese one-on-one and productive vocabulary at 24 months (n = 18) were found across languages and in each language independently. Differences are highlighted between previously published monolingual samples, which used the same methods as the current study of bilingual infants. The results also suggest cultural effects on language input and language development in bilingual and bicultural infants.
Heat transfer in flat-plate solar air-heating collectors

All energy systems involve processes of heat transfer. Solar energy is obviously a field where heat transfer plays crucial role. Solar collector represents a heat exchanger, in which receive solar radiation, transform it to heat and transfer this heat to the working fluid in the collector's channel. The radiation and convection heat transfer processes inside the collectors depend on the temperatures of the collector components and on the hydrodynamic characteristics of the working fluid Economically, solar energy systems are at best marginal in most cases. In order to realize the potential of solar energy, a combination of better design and performance and of environmental considerations would be necessary. This paper describes the thermal behavior of several types of flat-plate solar air-heating collectors.
Intratumoral infection by CMV may change the tumor environment by directly interacting with tumor-associated macrophages to promote cancer immunity

ABSTRACT Cytomegalovirus (CMV) is a herpesvirus that induces an extremely robust and sustained immune response. For this reason, CMV has been proposed as a vaccine vector to promote immunity to both pathogens and cancer. However, exploration of CMV as a vaccine vector is at an early stage and there are many questions. Using a mouse melanoma model, we recently found that a CMV-based vaccine induced large populations of melanoma-specific T cells, but was not effective at slowing tumor growth unless it was injected directly into the tumor. These surprising results have led us to hypothesize that CMV may be adept at modulating the tumor micro-environment through its infection of macrophages. Importantly, injection of CMV into the growing tumor synergized with blockade of the PD-1 checkpoint to clear well-established tumors. Here, we discuss our results in the context of CMV-based vaccines for pathogens and cancer.
Tuning T Cell Signaling Sensitivity Alters the Behavior of CD4+ T Cells during an Immune Response

Intricate processes in the thymus and periphery help curb the development and activation of autoreactive T cells. The subtle signals that govern these processes are an area of great interest, but tuning TCR sensitivity for the purpose of affecting T cell behavior remains technically challenging. Previously, our laboratory described the derivation of two TCR-transgenic CD4 T cell mouse lines, LLO56 and LLO118, which recognize the same cognate Listeria epitope with the same affinity. Despite the similarity of the two TCRs, LLO56 cells respond poorly in a primary infection whereas LLO118 cells respond robustly. Phenotypic examination of both lines revealed a substantial difference in their surface of expression of CD5, which serves as a dependable readout of the self-reactivity of a cell. We hypothesized that the increased interaction with self by the CD5-high LLO56 was mediated through TCR signaling, and was involved in the characteristic weak primary response of LLO56 to infection. To explore this issue, we generated an inducible knock-in mouse expressing the self-sensitizing voltage-gated sodium channel Scn5a. Overexpression of Scn5a in peripheral T cells via the CD4-Cre promoter resulted in increased TCR-proximal signaling. Further, Scn5a-expressing LLO118 cells, after transfer into BL6 recipient mice, displayed an impaired response during infection relative to wild-type LLO118 cells. In this way, we were able to demonstrate that tuning of TCR sensitivity to self can be used to alter in vivo immune responses. Overall, these studies highlight the critical relationship between TCR–self-pMHC interaction and an immune response to infection.
When a Baby Dies: A Systematic Review of Experimental Interventions for Women After Stillbirth

Objectives: To identify and evaluate intervention studies (ie, experimental study in which the participants undergo some kind of intervention in order to evaluate its impact) that target mental and/or physical health outcomes in women who have experienced stillbirth and to provide specific recommendations for future research and intervention work. Methods: A librarian conducted an initial search using CINAHL, Cochrane Library, PsycInfo, PubMed, SocIndex, and Web of Knowledge in the spring of 2016. Reference mining provided further articles. Articles were eligible if they were: (1) published in English, (2) published in a peer-reviewed journal, (3) published in 1980 or later, (4) an intervention that evaluated (qualitative or quantitative methods) mental and/or physical health, and (5) included women who had experienced a stillbirth (in utero fetal death at ≥20 weeks of gestation). Results: The combined searches produced 2733 articles (including duplicates). After duplicate articles were removed (n = 928), the research team screened the titles, abstracts, and full texts (when necessary) for eligibility (n = 1805). Two articles were identified that met our eligibility criteria. Conclusion for Practice: There is a lack of intervention research in women with stillbirth. It is imperative to develop and implement interventions to improve both mental and physical health in this population, especially in the interconception period (ie, stillbirth aftercare). Future intervention research is needed to determine appropriate support and efficacious delivery of support interventions, feasibility and effectiveness of physical activity interventions and complementary approaches, appropriate timing and dose of interventions, and culturally sensitive interventions appropriate for racial/ethnic minority women with stillbirth.
Apple‐Biowaste‐Derived Hard Carbon as a Powerful Anode Material for Na‐Ion Batteries

Modern industrial agriculture is strongly influenced by product norms and standards, resulting in massive amounts of fresh fruit that is left in the field or wasted in spite of their good nutritional value. Herein, we present the synthesis of hard carbon from natural apple biowaste, and its use of biomass is a suitable strategy for the development of cheap and powerful carbon-based active materials for Na-ion batteries. The hard carbon exhibits a good rate capability [112 mAh g−1 at 5 C (1 A g−1)], excellent long-term cycling stability (1000 cycles at 5 C), and high specific capacity (245 mAh g−1 at 0.1 C) with full retention after 80 cycles. The full capacity (250 mAh g−1) of the hard carbon is also obtained in Na-ion cells by using the layered P2-type NaxNi0.22Co0.11Mn0.66O2 cathode. The good electrochemical performance as well as the low cost and environmental friendliness of the apple-biowaste-derived hard carbon proves its suitability for future Na-ion batteries.
Evaluating the REA Enterprise Ontology from an Operational Perspective

Recently, there has been an increasing interest in building ontologies for the enterprise domain, and a number of attempts already exist [4,16]. The Resources/Events/Agents model (REA) is one such ontology. In the following we describe the challenges we have experienced in understanding the REA model’s most central ontological pattern, the economic exchange. The result is three points, which we argue are pivotal to success when constructing enterprise ontologies: (1) a rigorous instance/type distinction, (2) a strong emphasis on cardinalities between the objects involved, and (3) a thorough analysis of the trade-offs between size and fit. Using these three points as guidance will speed up the process of building ontologies for interoperability. The overall lesson learned is that postponement of the operational aspects of the ontology should be avoided.
A general system for heuristic minimization of convex functions over non-convex sets

We describe general heuristics to approximately solve a wide variety of problems with convex objective and decision variables from a non-convex set. The heuristics, which employ convex relaxations, convex restrictions, local neighbour search methods, and the alternating direction method of multipliers, require the solution of a modest number of convex problems, and are meant to apply to general problems, without much tuning. We describe an implementation of these methods in a package called NCVX, as an extension of CVXPY, a Python package for formulating and solving convex optimization problems. We study several examples of well known non-convex problems, and show that our general purpose heuristics are effective in finding approximate solutions to a wide variety of problems.
Posttraumatic Stress Disorder and Alcohol Dependence: Epidemiology and Order of Onset

Objective: Posttraumatic stress disorder (PTSD) and alcohol dependence (AD) frequently co-occur; however, epidemiologic studies of temporal associations between PTSD and AD are limited. The aims of this study were (a) to investigate the bidirectional associations between PTSD and AD and (b) to examine demographic and clinical correlates of order-of-onset among individuals with PTSD and AD. Method: Participants were 11,103 adults (60.6% women; Mage = 48.7 years, SD = 15.9) from the National Epidemiologic Survey on Alcohol and Related Conditions who endorsed lifetime alcohol consumption and DSM–IV PTSD Criterion A trauma exposure (American Psychiatric Association, 2000). Cox proportional hazards models with time-dependent covariates were used to evaluate bidirectional associations between PTSD and AD. Sex differences were assessed using stratified analyses. Results: After adjusting for demographic, trauma, and alcohol characteristics, PTSD was associated with greater likelihood of subsequent AD (hazard ratio [HR] = 1.359, 95% CI = 1.357–1.362), and AD was associated with greater likelihood of subsequent PTSD (HR = 1.274, 95% CI = 1.271–1.277). Bidirectional associations between PTSD and AD were stronger for women compared with men. Among individuals with PTSD and AD, initial onset of PTSD was associated with younger age of first potentially traumatic event. Initial onset of AD was associated with earlier initiation of alcohol use, earlier onset of heavy alcohol use, family history of alcohol problems, and history of generalized anxiety disorder and social anxiety disorder for women but not men. Initial AD was associated with lifetime panic disorder for men and women. Conclusions: Etiology of PTSD and AD is heterogeneous, and order of onset may reflect differing risk pathways.
Blueprint for the Intercloud - Protocols and Formats for Cloud Computing Interoperability

Cloud Computing is a term applied to large, hosted datacenters, usually geographically distributed, which offer various computational services on a “utility” basis. Most typically the configuration and provisioning of these datacenters, as far as the services for the subscribers go, is highly automated, to the point of the service being delivered within seconds of the subscriber request. Additionally, the datacenters typically use hypervisor based virtualization as a technique to deliver these services. The concept of a cloud operated by one service provider or enterprise interoperating with a clouds operated by another is a powerful idea. So far that is limited to use cases where code running on one cloud explicitly references a service on another cloud. There is no implicit and transparent interoperability. Use cases for interoperability, as well as work-in-progress around inter-cloud protocols and formats for enabling those use cases, are discussed in this paper.
A Process for Controlling Intracellular Bacterial Infections Induced by Membrane Injury

Strategies for inhibiting phagolysosome fusion are essential for the intracellular survival and replication of many pathogens. We found that the lysosomal synaptotagmin Syt VII is required for a mechanism that promotes phagolysosomal fusion and limits the intracellular growth of pathogenic bacteria. Syt VII was required for a form of Ca2+-dependent phagolysosome fusion that is analogous to Ca2+-regulated exocytosis of lysosomes, which can be triggered by membrane injury. Bacterial type III secretion systems, which permeabilize membranes and cause Ca2+ influx in mammalian cells, promote lysosomal exocytosis and inhibit intracellular survival in Syt VII +/+ but not –/– cells. Thus, the lysosomal repair response can also protect cells against pathogens that trigger membrane permeabilization.