Miracle-dz/UniFAR-FTUs huggingface dataset:
Hypoxia‐inducible factors as key regulators of tumor inflammation

Low levels of oxygen or hypoxia is often an obstacle in health, particularly in pathological disorders like cancer. The main family of transcription factors responsible for cell survival and adaptation under strenuous conditions of hypoxia are the “hypoxia‐inducible factors” (HIFs). Together with prolyl hydroxylase domain enzymes (PHDs), HIFs regulates tumor angiogenesis, proliferation, invasion, metastasis, in addition to resistance to radiation and chemotherapy. Additionally, the entire HIF transcription cascade is involved in the “seventh” hallmark of cancer; inflammation. Studies have shown that hypoxia can influence tumor associated immune cells toward assisting in tumor proliferation, differentiation, vessel growth, distant metastasis and suppression of the immune response via cytokine expression alterations. These changes are not necessarily analogous to HIF's role in non‐cancer immune responses, where hypoxia often encourages a strong inflammatory response.
Interpersonal Affect and Peer Rating Bias in Teams

This study assessed the consequences of performance feedback received from peers on a team member’s subsequent ratings of others, and the mediating influence of interpersonal affect. Undergraduate participants (N = 142) working in 30 teams during a 7-week period were assigned collective bargaining and arbitration tasks. We found that a team member’s prior positive or negative peer feedback resulted in increased leniency or severity, respectively, and increased restriction in range when these same members subsequently rated fellow team members. Interrater agreement on ratings of peers at Time 3 was higher when raters received similar feedback (i.e., both received positive or negative feedback) from their peers at the Time 1. The mechanism through which feedback at Time 1 influenced rating biases at Time 3 was found to be interpersonal affect (measured at Time 2).
DnaJC18, a Novel Type III DnaJ Family Protein, is Expressed Specifically in Rat Male Germ Cells

ABSTRACT Mammalian spermatogenesis occurs in a precise and coordinated manner in the seminiferous tubules. One of the attempts to understand the detailed biological process during mammalian spermatogenesis at the molecular level has been to identify the testis specific genes followed by study of the testicular expression pattern of the genes. From the subtracted cDNA library of rat testis prepared using representational difference analysis (RDA) method, a complimentary DNA clone encoding type III member of a DnaJ family protein, DnaJC18, was cloned (GenBank Accession No. DQ158861). The full-length DnaJC18 cDNA has the longest open reading frame of 357 amino acids. Tissue and developmental Northern blot analysis revealed that the DnaJC18 gene was expressed specifically in testis and began to express from postnatal week 4 testis, respectively. In situ hybridization studies showed that DnaJC18 mRNA was expressed only during the maturation stages of late pachy- tene, round and elongated spermatids of adult rat testis. Western blot analysis with DnaJC18 antibody revealed that 41.2 kDa DnaJC18 protein was detected only in adult testis. Immunohistochemistry study further confirmed that DnaJC18 protein, was expressed in developing germ cells and the result was in concert with the in situ hybridization result. Confocal microscopy with GFP tagged DnaJC18 protein revealed that it was localized in the cytoplasm of cells. Taken together, these results suggested that testis specific DnaJC18, a member of the type III DnaJ protein family, might play a role during germ cell maturation in adult rat testis.
Wealth and the Quality of Life for Physical Education Teachers

Purpose. The purpose of the study was to assess the perceived quality of life of physical education teachers depending on their standard of living. Methods. The study included 287 graduates of the University Schools of Physical Education in Poznań and Wrocław, of whom 165 were men and 122 were women aged 40 to 60 years. The perceived quality of life was assessed on the basis of Kowalik’s Quality of Life Questionnaire. The relationship between the perceived quality of life and the standard of living was then established, with statistical analysis performed using two stratum weights ( k ), the Mann-Whitney U -test and Spearman’s rank correlation ( r ). Results. The majority of the studied participants positively assessed their lives, with no significant differentiation found between genders in their satisfaction in various spheres of life. However, only half of the respondents were satisfied by their level of income. A higher standard of life was found to be linked to higher life satisfaction, where the level of wealth significantly differentiated only in the perceived quality of life in the studied women. Conclusions. The surveyed graduates were found to be a very homogenous group of professionals in terms of their quality of life level. Only financial status was found to significantly differentiate in the level of satisfaction of the surveyed women.
School Characteristics Related to Student Engagement.

It is well established that American students at risk often exhibit patterns of emotional and behavioral withdrawal or disengagement from school. These withdrawal behaviors may culminate in complete disengagement, that is, leaving school without graduating. This investigation examines aspects of the structural and regulatory environment of schools to identify features that are associated with higher levels of engagement among eighth-grade students at risk.
Emotional gaze behavior generation in human-agent interaction

Gaze behavior plays an important role in face to face communication in that it conveys nonverbal information and emotional intent beyond speech. This research proposes a computational framework for generating emotional gaze behavior in a virtual agent, concentrating on analysis and synthesis of primary and intermediate emotions through gaze behavior. We utilize parameters picked from the AU-Coded facial expression database and real-time eye movement data (pupil size, blink rate and saccade) to model primary emotions and describe a rule-based approach to generate intermediate ones.
Accounting change: explaining the outcomes, interpreting the process

Purpose - The issue of accounting change, why and how accounting evolves through time and within specific organisational settings, has been addressed by an important body of literature. This paper aims to explain why, in processes of accounting change, organisations confronting similar environmental pressures show different outcomes of change. Design/methodology/approach - Drawing on archetype theory, the paper analyses the case of two Italian local governments. Comparative case studies were carried out, reconstructing a period of 15 years. Findings - Although confronted with similar environmental pressures, the two cases show two different patterns of accounting change, where only one case is able to finally reach radical change. Accounting change can be prompted by external stimuli, but, once the change is prompted, the outcomes of the change are explained by the dynamics of intra-organisational conditions. Originality/value - The study contributes to accounting change literature by adopting an approach (i.e. archetype theory) that overcomes some of the limitations of previous studies in explaining variations in organisational change. Through this, the authors are able to explain different outcomes and paces of accounting change and point out the intra-organisational factors also affecting them in the presence of similar environmental pressures. A specification of the theoretical framework in a particular setting is also provided.
The Process of Adaptation Following a New Diagnosis of Type 1 Diabetes in Adulthood: A Meta-Synthesis

While Type 1 diabetes (T1D) is generally associated with childhood, half of all cases occur in adulthood. The adaptive strategies individuals employ during the initial adaptive phase may have an important impact on their risk of future diabetes complications and their psychosocial well-being. We conducted a systematic review of six databases and included nine qualitative studies in a meta-synthesis, the aims of which were to develop a better understanding of how adults newly diagnosed with T1D experience the diagnosis and the phenomena associated with the early process of adaptation to life with diabetes. The meta-synthesis identified five constructs that shaped and influenced the early adaptive process: disruption, constructing a personal view of diabetes, reconstructing a view of self, learning to live with diabetes, and behavioral adaptations. The adaptive processes of adults to a diabetes diagnosis are highly referenced to prior life experiences, social habitus, and psychological orientation.
Modeling of mutual coupling between inductors

This paper is devoted to EMI filter inductor modeling and mutual coupling modeling between two inductors positioned on PCB. 3D inductor models are developed and modeled in CST MWS. Comparison of inductors mutual coupling measurement and modeling results show that transfer coefficients can be predicted accurately. CST MWS has been used also to predict effective mutual coupling reduction techniques.
Sex, Drugs, and Kinesiology: A Useful Partnership for Sport’s Most Pressing Issues

From the gender controversy of South African runner Caster Semenya to the doping practices of disgraced American cyclist Lance Armstrong, recent sporting issues highlight kinesiology’s important role and responsibility to sport. Increasingly, sport organizations, such as the International Olympic Committee, the World Anti-Doping Agency, and international federations, have turned to academics to help navigate their sport science issues. Such complex, cross-disciplinary problems require researchers versed in kinesiology’s sub-disciplines and familiar with problem-based inquiry. Though such cross-disciplinary practices are familiar to kinesiologists, their familiarity only indicates kinesiology’s potential impact on the major issues sport is currently addressing. Kinesiology must be a field comprised of scholars equally comfortable with empirical and humanistic research while at the same time applying their cross-disciplinary knowledge to some of sport’s most pressing issues. Kinesiology ought to consider more collaborative venues for scholars from across its sub-disciplines to work together on complex, cross-disciplinary research.
The Organization of Production and its Publics: Mental Proximity, Market and Hierarchies

Abstract The paper introduces mental proximity as an ideal-type criterion for assessing the organization of production, and positions it as a benchmark alongside markets and hierarchies in a three-dimensional space. Following a Deweyan approach, the criterion is focused on democratic deliberation espoused by necessary values: the rejection of controlling influences, positive freedom, inclusion on equal terms, informed participation, the desire to reach a consensus, sympathy, mutual respect, reciprocity, and continuous learning. We also identify a community network as a complex of people who seek to relate to each other in accord with mental proximity, and discuss influences on their search.
Optimal Automated Method for Collaborative Development of University Curricula

Aspects of curriculum design automation using semantic analysis of Web texts to develop candidate keywords and voting alternatives, as well as methods of optimal aggregation of individual expert decisions are presented. It is shown how semantics analysis of online texts can help with: generating of initial version of the curriculum; generating of candidate keywords and alternative options for improving the curriculum; building hierarchy of categories of the subject area or domain; detecting the change of domain knowledge state and defining structural knowledge dependencies; monitoring terminology and knowledge base of the subject area or domain. It is shown how the techniques of optimal integration of individual expert decisions in selecting of automatically generated alternatives helps to create the highest quality curriculum.
A Faster Approximate Minimum Steiner Tree Algorithm & Primal-Dual and Local-Ratio Greedy Algorithms

We prove matching upper and lower bounds for the Minimum Steiner Tree (MStT) problem within the adaptive priority stack model introduced by Borodin, Cashman, and Magen [2] and lower bounds within the adaptive priority queue model introduced here. These models, which are extensions of the adaptive priority model of Borodin, Nielson, and Rackoff [4], are said to capture reasonable primal-dual and local-ratio extensions of greedy algorithms. Borodin etal. [2] had proved lower bound 1 3 on the approximation ratio obtainable for the problem in the stack model. We improve this to 2−O( 1 |V | ). This and similar results prove that the above upper bound is tight, that the adaptive priority stack model is incomparable with the fully adaptive priority branching tree (pBT) model, and that the online stack model is incomparable with the adaptive priority model. We also prove a lower bound in the priority model for complete graphs improving the result of Davis and Impagliazzo [6] from 1 4 to 1 1 3 . The priority queue model is better because ? Within it we prove a 7 6 approximation lower bound.
Rendering compact discs and other diffractive surfaces illuminated by linear light sources

In this paper we develop an analytic model for determining the reflection from a compact disc illuminated by linear light sources. This model can easily be applied to any other diffractive surface when the diffractive characteristics of the surface are known.The reflection is determined by representing the linear light source with a parameterized function and using crystal lattice theory to provide a set of equations which can be solved to determine the reflected wavelengths. This model is an extension to previously developed models describing compact disc reflection.Studies of our model are made by comparing renderings of a compact disc illuminated by linear light source with actual photographs taken under similar conditions. The result shows that the reflection from linear light sources, which yields a different reflection pattern than point light sources, can be rendered in a time comparable with earlier point light source models.
Exercise as Punishment

Abstract Background: Lack of exercise and physical inactivity have been implicated as contributors to obesity and overweight in America. At a time where experts point to the need for increased exercise, many youth have experienced exercise as a form of punishment, which appears to be imbedded in physical education and sport culture. Purpose: This study uses the theory of planned behavior (TPB) to examine and predict the use of exercise as punishment (EAP) by coaches and physical education teachers. Methods: Surveys based on the TPB were completed by 189 physical education teachers and coaches. Results: More than 60% of respondents indicated that they had used EAP; the theory's constructs were able to explain 68% of the variance in participants' intentions to use EAP, with attitude and subjective norm being significant predictors. Discussion: The use of exercise as punishment by many teachers and coaches may contribute to lack of enjoyment and lack of participation in exercise and sport. Further research needs to address the consequences of this practice and to determine if it does lead to future inactivity. Translation to Health Education Practice: Teachers and coaches need to be educated about the possible negative impact of EAP and positive alternative approaches to behavior management.
Martin Buber and Dialogical Psychotherapy

This article has a quadruple thrust: first, to present Martin Buber’s philosophy of dialogue; second, to give a full account of Maurice Friedman’s 10 elements of Dialogical Psychotherapy; third, to portray Martin Buber’s influence on the theory and practice of several psychotherapists and psychoanalysts; and thus to depict the growing range of what the author calls the Dialogical Psychotherapy Movement. Accordingly, the article is divided into the following sections: an introduction; Buber’s “Life of Dialogue”; a definition of Dialogical Psychotherapy; a presentation of the elements of Dialogical Psychotherapy; two illustrations of Dialogical Psychotherapy in practice; a brief discussion of “Therapists of Dialogue,” who use some of the elements of Dialogical Psychotherapy without making “healing through meeting” central; three sections on therapists who do make healing through meeting central, namely, Dialogical Psychotherapists proper, Relational Psychoanalysts, and Contextual (intergenerational family) Therapists; and a conclusion that briefly summarizes the article and the significance of the Dialogical Psychotherapy Movement.
On the Effectiveness of Simultaneous Multithreading on Network Server Workloads

This paper experimentally investigates the effectiveness of simultaneous multithreading (SMT) for network server workloads. We study how well SMT improves performance on two very different shipping platforms that support SMT: IBM’s POWER5 and the Intel Xeon. We use the architectural performance counters available on each processor to compare their architectural behavior, examining events such as cache misses, pipeline stalls, etc. By observing how these events change in response to the introduction of threading, we can determine whether and how SMT stresses the system. We find that POWER5 makes more effective use of SMT for improving performance than the Xeon. In general, POWER5 achieves a 40-50% increase whereas the Xeon exhibits only a 10-30% gain. Examination using the performance counters reveals that cache size and memory bandwidth are the key requirements for fully exploiting SMT. A secondary but still noticeable component is minimizing pipeline stalls due to branch mispredicts and interrupts. We present suggestions for improving SMT performance for each platform based on our observations.
An Examination of the Postmortem Redistribution of Fentanyl and Interlaboratory Variability ,

Fentanyl is a synthetic opioid agonist used for pain control. Often administered as a transdermal patch, it is an interesting drug for study of postmortem redistribution. We hypothesized that fentanyl concentrations would increase over time after death, as measured in blood drawn on the day prior to autopsy and in blood drawn at the time of autopsy in ten cases where fentanyl patches were identified at the scene. Concentrations were compared, and heart blood to femoral blood ratios were calculated as markers of postmortem redistribution. Fentanyl concentrations measured in peripheral blood drawn the day of autopsy (peripheral blood 2 [PB2]) were higher than those drawn the day prior to autopsy (peripheral blood 1 [PB1]) with a mean ratio (PB2/PB1) of 1.80. The ratio of heart blood concentrations (HB) to femoral blood concentrations drawn at autopsy (PB2) had a mean ratio (HB/PB2) of 1.08. Some cases had blood from the same source analyzed at two different laboratories, and concentrations of fentanyl in those samples showed inter‐ and intralaboratory differences up to 25 ng/mL. Postmortem fentanyl concentrations may be affected by antemortem factors, postmortem redistribution, and laboratory variability. Forensic pathologists must use caution in interpreting fentanyl levels as part of death investigation.
Intel Ivy Bridge unveiled — The first commercial tri-gate, high-k, metal-gate CPU

The year 2007 saw the introduction of the first high-k/metal gate (HKMG) devices into the marketplace. This marked the return of metal-gate technology on silicon for the first time since polysilicon gates became ubiquitous in the early 1970s. Intel was the first to use high-k/metal gate in its 45-nm product. Other leading-edge manufacturers have now launched HKMG products in both gate-first and gate-last forms, and now the first 22-nm FinFET products have come onto the market - the Intel Ivy Bridge CPU. Chipworks, as a supplier of competitive intelligence to the semiconductor and electronics industries, monitors the evolution of chip processes as they come into commercial production. Chipworks has obtained samples of this leading-edge part and performed structural analyses to examine the features and manufacturing processes of the device. This paper discusses some of the different features we have seen within the chip, and illustrates the structure of the tri-gate transistors.
Women's representation and gender quotas: the case of the Polish parliament

Representation is inherent to democracy and truly representative institutions are vital for a good quality democracy. However, the argument that parliaments are not sufficiently representative because of female under-representation is widespread. A number of countries around the world have introduced gender quotas in order to enhance the descriptive representation of women. This article analyses women's representation and the adoption of gender quotas in Poland. After several unsuccessful attempts, the law was finally approved in 2011. Veto players analysis is used to explain this policy change.
The Industry Settings of Leading Organizational Research: The Role of Economic and Non-Economic Factors

Despite calls for attention to the role of context in organizational research, there have been no assessments of the distribution of industry contexts in organizational research. This paper explores that distribution in relation to the industry composition of the U.S. economy. Our analysis of 914 empirical field studies published in four leading journals from 1988 to 2002 reveals striking, persistent, and growing discrepancies between the industries that are economically important and the industries that have served as settings for organizational research. For example, education and manufacturing are oversampled in relation to their economic importance, while real estate, construction, wholesale, and retail are undersampled. We also develop and test a series of hypotheses predicting which industries serve as the contexts for leading research. Using negative binomial regression, we show that the percentage of recent MBA graduates in an industry and the percentage of employees with doctoral degrees in an industry predict the number of articles set in that industry, with the total number of employees and average establishment size in an industry enhancing the power of the model. We conclude by discussing the implications of our findings for advancing organizational theory and research methods.
An Exploratory Study of the Career Driver Scores of Accounting-major Students in Hong Kong

ABSTRACT This is an exploratory study profiling the career drivers of final-year accounting- major students at four tertiary institutions in Hong Kong. Specifically, the study identifies what an accounting-major student is looking for in a career. Comparative examinations of the career drivers are performed by the gender and institutional criteria. The career driver scores of accounting-major and non-accounting business students are also compared. The results suggest the presence of statistically significant differences between male and female accounting-major students in the career drivers of material rewards, search for meaning in their career, creativity, job security and job status. When institutional setting is used as a basis of comparison, there are statistically significant differences among the accounting-major students in the areas of material rewards, creativity, affiliation, security and status. Accounting- major and non-accounting business students exhibit differences in the career drivers of.