Miracle-dz/UniFAR-FTUs huggingface dataset:
Etude des instabilités d'un jet plan à masse volumique variable

L'influence de la variation de masse volumique pour le developpement des instabilites primaires d'un jet plan est etudiee par simulation numerique directe des equations de Navier-Stokes incompressibles. Chaque methode numerique retenue ainsi que la construction du programme sont detaillees pas a pas en insistant particulierement sur le choix des conditions aux limites. La methode est validee par une etude lineaire qui presente des resultats pour une large gamme de valeurs du rapport de densite. A partir de ce code non lineaire, on etudie la transition convective/absolue subie par le mode variqueux lorsque le rapport de densite diminue pour differents profils dont le Bickley et le presque top-hat. Une remise en cause du critere de stabilite marginale est proposee. En outre, l'observation inattendue de modes globaux amortis pour les rapports de densite voisins de 1 dans le cas d'un profil presque top-hat nous conduit a proposer une hypothese en etudiant l'equation analytique implicite qui definit la relation de dispersion du mode variqueux pour un profil top-hat. Une courte etude experimentale dans laquelle on presente les differentes techniques employees, ainsi que les premieres mesures de vitesse et de densite, complete ce travail, en donnant des informations sur les frequences caracteristiques.
Modelos de aprendizaje basados en programación genética para Clasificación Multietiqueta

El problema de clasificacion consiste en asociar una serie de etiquetas a una serie de ejemplos o patrones. En la clasificacion clasica a cada patron de entrenamiento solamente se le puede asociar una sola etiqueta de un conjunto de etiquetas. Por tanto se consideran que los conjuntos de clases objetivo en los que se agruparan los patrones son por definicion conjuntos disjuntos. En el caso de la clasificacion multi-etiqueta, los conjuntos objetivos no son disjuntos, pudiendo haber patrones a los que se les asocie mas de una etiqueta. Por tanto, los ejemplos se asocian a un conjunto de etiquetas y el resultado puede tomar varios valores dentro del conjunto de etiquetas[1]. El objetivo que se plantea en esta tesis es el desarrollo de una serie de modelos de programacion genetica para resolver problemas de clasificacion multi-etiqueta.
A CMOS voltage reference

A method for developing a reference voltage in CMOS integrated circuits is described. The circuit uses MOS devices operating in the weak inversion region, as well as a bipolar device formed without process modifications. A brief description of this region of operation is given. Then, the principle of the suggested voltage reference is explained and the final implementation is presented. Higher order effects are discussed, and results from an integrated prototype given.
Crystal structure of a nuclear actin ternary complex

Significance Actin is a prominent component of the cytoskeleton in the cytoplasm of eukaryotic cells. Its presence in the nucleus was once considered controversial. However, it is now widely accepted that nuclear actin (N-actin) is a constitutive subunit of several chromatin-remodeling complexes. Yet, the specific structure of N-actin and how its polymerization is regulated remain unresolved. Our study presents the first crystal structure of the N-actin complex to our knowledge and illustrates the salient features that distinguish N-actin from its cytoplasmic counterpart. These features prevent the self-polymerization of N-actin and its regulation by many known actin-binding proteins. Our findings provide a rational basis for the functions of N-actin, laying the groundwork for future studies in this field. Actin polymerizes and forms filamentous structures (F-actin) in the cytoplasm of eukaryotic cells. It also exists in the nucleus and regulates various nucleic acid transactions, particularly through its incorporation into multiple chromatin-remodeling complexes. However, the specific structure of actin and the mechanisms that regulate its polymeric nature inside the nucleus remain unknown. Here, we report the crystal structure of nuclear actin (N-actin) complexed with actin-related protein 4 (Arp4) and the helicase-SANT–associated (HSA) domain of the chromatin remodeler Swr1. The inner face and barbed end of N-actin are sequestered by interactions with Arp4 and the HSA domain, respectively, which prevents N-actin from polymerization and binding to many actin regulators. The two major domains of N-actin are more twisted than those of globular actin (G-actin), and its nucleotide-binding pocket is occluded, freeing N-actin from binding to and regulation by ATP. These findings revealed the salient structural features of N-actin that distinguish it from its cytoplasmic counterpart and provide a rational basis for its functions and regulation inside the nucleus.
On-chip current flattening circuit with dynamic voltage scaling

This paper presents the circuit-level implementation for a current flattening system designed to control the power-supply current and to protect cryptosystems from power analysis attacks. When required, the proposed circuit dynamically controls the power consumption by injecting an extra current and by scaling the power-supply voltage. The circuit can be integrated on the same chip with a cryptographic processor. In this way the power-supply current has little meaningful information for a side-channel attack. The proposed circuit has been designed in a 0.18 mum CMOS technology and operates with a nominal 1.8-V power supply
Research of face recognition based on wavelet transform and principal component analysis

Principal component analysis (PCA) has been applied in many face recognition systems, and achieved very good results. However, PCA has its limitations: a large amount of calculation and very low capacity of identification. In order to overcome these disadvantages, a new face recognition algorithm which is based on wavelet transform, principal component analysis and minimum distance classifier is proposed in the paper. The simulation experiments based on ORL face database show that the method not only improves the recognition rate, but also reduces the amount of computation. When the training sample is very large, the effectiveness of recognition systems is particularly important.
The self-management balancing act of spousal care partners in the case of Parkinson’s disease

Abstract Background: Living with and caring for someone with chronic illness can lead to limitations in activity and social participation for the care partner. Past research emphasizes the importance of care partners taking care of themselves physically and emotionally so they can stay healthy to support the care recipient. There is little information regarding how the care partner takes care of their own social lives. The purpose of this study was to explore the concept of social self-management from the perspective of spousal care partners of people with Parkinson’s disease. Method: Twenty spousal care partners of people with Parkinson’s disease were interviewed three times. A grounded theory approach informed data analysis. Results: Findings that emerged from the data focused on balance in activities, support, and emotions and were summarized into three main themes: (1) Activities: Caregiving and beyond; (2) Strategies to support self and spouse; and (3) Emotional impact: Burden and compassion. Conclusion: This research shows that care partners want to retain social participation and provides support for the importance of addressing the socio-emotional needs of care partners of people with a chronic disease. Interventions that guide care partners to take care of their spectrum of needs may lead to healthier, positive relationships. Implications for rehabilitation The focus of rehabilitation is often on the person diagnosed with the chronic condition. Living with and caring for someone with a chronic illness, such as Parkinson’s disease, can lead to limitations in activity and social participation for the care partner. Including care partners in the rehabilitation process is key to helping maintain their health and well-being. Learning caregiving and self-management strategies may help care partners support their loved ones while staying socially engaged.
A design approach for server power supplies for networking applications

Present specifications for computer power supplies for networking applications call for designs with dual inputs: the universal AC-line input and the 48-V nominal DC input. In this paper, a design and evaluation of the DC-input version of a 900-W server power supply is presented. The AC-input version of this power supply is leveraged from the AC-input version by using the same output stage, and by replacing the AC front-end in the AC-input version with a DC front end which provides the same input voltage to the output stage. By adopting this design approach, it is possible to achieve design modularity, design standardization, minimize the design time, optimize utilization of resources, and minimize the cost. The DC-input version uses a cascade connection of two DC boost converters because of its superior performance compared with other topologies.
Dynamic variables of fluid responsiveness during pneumoperitoneum and laparoscopic surgery

Few data exist on dynamic variables predicting fluid responsiveness during laparoscopic surgery. The aim of this study was to explore the effects of laparoscopy on four dynamic variables: respiratory variations in pulse pressure (ΔPP), stroke volume variation by Vigileo/FloTrac (SVV Vigileo), pleth variability index (PVI) and respiratory variations in pulse oximetry plethysmography waveform amplitude (ΔPOP), and their relation to fluid challenges during laparoscopic surgery.
CogSketch: Sketch Understanding for Cognitive Science Research and for Education

Sketching is a powerful means of working out and communicating ideas. Sketch understanding involves a combination of visual, spatial, and conceptual knowledge and reasoning, which makes it both challenging to model and potentially illuminating for cognitive science. This paper describes CogSketch, an ongoing effort of the NSF-funded Spatial Intelligence and Learning Center, which is being developed both as a research instrument for cognitive science and as a platform for sketch-based educational software. We describe the idea of open-domain sketch understanding, the scientific hypotheses underlying CogSketch, and provide an overview of the models it employs, illustrated by simulation studies and ongoing experiments in creating sketch-based educational software.
The Maturity of Tourism Networks: An Exploratory Study

Networks in tourism are a growing phenomenon worldwide and tourism literature has devoted considerable space to networks’ policies, governance forms, competitive advantages and activities. Literature that focuses on networks’ operations generally analyzes what kind of activities are put in place without examining how they are carried out and whether they generate a competitive advantage. To fill this gap, our paper provides a notion of network maturity and introduces a taxonomy of the maturity levels of a network’s operations. The three-stage maturity model contributes to tourism literature by exploring how networks can evolve from basic to more sophisticated operations. From a managerial perspective, the paper contributes to evaluating network effectiveness and defining paths to improve it.
Effects of residue background events in direct dark matter detection experiments on the determination of the WIMP mass

In the earlier work on the development of a model-independent data analysis method for determining the mass of Weakly Interacting Massive Particles (WIMPs) by using measured recoil energies from direct Dark Matter detection experiments directly, it was assumed that the analyzed data sets are background-free, i.e., all events are WIMP signals. In this article, as a more realistic study, we take into account a fraction of possible residue background events, which pass all discrimination criteria and then mix with other real WIMP-induced events in our data sets. Our simulations show that, for the determination of the WIMP mass, the maximal acceptable fraction of residue background events in the analyzed data sets of (50) total events is ~ 20%, for background windows of the entire experimental possible energy ranges, or in low energy ranges; while, for background windows in relatively higher energy ranges, this maximal acceptable fraction of residue background events can not be larger than ~ 10%. For a WIMP mass of 100 GeV with 20% background events in the windows of the entire experimental possible energy ranges, the reconstructed WIMP mass and the 1σ statistical uncertainty are ~ 97GeV+61%−35% ( ~ 94GeV+55%−33% for background-free data sets).
Proviral Loads and Clonal Expansion of HTLV-1-Infected Cells following Vertical Transmission: A 10-Year Follow-Up of Children in Jamaica

Objective: Few studies have specifically examined proviral load (PVL) and clonal evolution of human T-lymphotropic virus type 1 (HTLV-1)-infected cells in vertically infected children. Methods: Sequential samples (from ages 1 to 16 years) from 3 HTLV-1-infected children (cases A, B and C) in the Jamaica Mother Infant Cohort Study were analyzed for their PVL and clonal expansion of HTLV-1-infected cells in peripheral blood mononuclear cells (PBMCs) by inverse-long PCR. Results: The baseline PVL (per 100,000 PBMCs) of case A was 260 (at 1 year of age) and of case B it was 1,867 (at 3 years of age), and they remained constant for more than 10 years. Stochastic patterns of clonal expansion of HTLV-1-infected cells were predominately detected. In contrast, case C, who had lymphadenopathy, seborrheic dermatitis and hyperreflexia, showed an increase in PVL from 2,819 at 1.9 years to 13,358 at 13 years of age, and expansion of 2 dominant clones. Conclusion: The clonal expansion of HTLV-1-infected cells is induced in early childhood after infection acquired from their mothers. Youths with high PVL and any signs and symptoms associated with HTLV-1 infection should be closely monitored.
The effects of the BEPS Action Plans on the tax avoidance behaviors of multinational corporations in China

Multinational corporations (MNCs) around the globe commonly use cross-border related-party transactions (CRPTs) to shift profits from high tax jurisdictions to low ones to avoid paying taxes. The Organization for Economic Co-operation and Development and G20 countries launched the Base Erosion and Profit Shifting (BEPS) Action Plans in 2013 to constrain tax avoidance behaviors of MNCs, particularly the widespread use of CRPTs. This study examines how the localization of the BEPS Action Plans affects the tax avoidance behavior of MNCs in China. Using all the listed non-financial MNCs on the Stock Exchanges in China from 2012 to 2017, I find that: (1) Chinese MNCs with more CRPTs are more likely to pay less taxes than those with less CRPTs. Localization of the BEPS Action Plans does not have significant impact on this behav-ior. (2) The effect of localization of BEPS Action Plans to constrain corporate tax avoid-ance is more pronounced on MNCs with relatively poor information quality in the pre-location period; (3) local government-controlled firms (LG firms) with more CRPTs en-gage in more tax avoidance, but localization of the BEPS Action Plans significantly constrains tax avoidance activities by these firms in the post-location period. These findings should shed light on what mechanisms could constrain MNCs’ tax avoidance, especially income shifting through CRPTs, and how it could be affected by tightening of the tax laws on tax avoidance activities and by ownership structure in a developing country setting, in particular.
The Quantum Hydrodynamic Model for Semiconductor Devices

The classical hydrodynamic equations can be extended to include quantum effects by incorporating the first quantum corrections. These quantum corrections are $O( {\hbar ^2 } )$. The full three-dimensional quantum hydrodynamic (QHD) model is derived for the first time by a moment expansion of the Wigner–Boltzmann equation. The QHD conservation laws have the same form as the classical hydrodynamic equations, but the energy density and stress tensor have additional quantum terms. These quantum terms allow particles to tunnel through potential barriers and to build up in potential wells.The three-dimensional QHD transport equations are mathematically classified as having two Schrodinger modes, two hyperbolic modes, and one parabolic mode. The one-dimensional steady-state QHD equations are discretized in conservation form using the second upwind method.Simulations of a resonant tunneling diode are presented that show charge buildup in the quantum well and negative differential resistance (NDR) in the current-v.
Flash microbiocide: A Rapid and Economic Method for Determination of MBC and MFC

Although nowadays there are methods for determining the Minimal Bactericidal Concentration and Minimal Fungicidal Concentration, it is indispensable that the establishment of innovative methodologies could be more practical and cheaper. The new methodology Flash microbiocide is an assay in which one aliquot from 96 well plate of Minimal Inhibitory Concentration test is transferred to another plate containing different culture medium. The correspondence with the reference methods described in the National Committee for Clinical Laboratory Standards (NCCLS-CLSI) document M26-A was achieved, denoting the efficiency of this fast and simple method.
Efficient Analysis of Closed Frequent Pattern Set Mining Approach

: Many researchers’ unreal the ideas to get the frequent item sets/ pattern sets. Some frequent pattern mining often produces a large number of frequent patterns, which imposes a great challenge on visualizing, understanding and further analysis of the generated patterns. This emerges the need for finding small number frequent occurring patterns. The time needed for generating frequent pattern sets plays associate important role. Some algorithms are designed, considering solely the time issue. Our study includes analysis of algorithms that are used to find frequent pattern sets by using the technique of closed pattern sets.
On the interaction between personal comfort systems and centralized HVAC systems in office buildings

ABSTRACT Most modern HVAC systems in office buildings are unable to meet diverse comfort requirements of the occupants and are not energy efficient. We propose to mitigate both issues by using personal comfort systems (PCS). Specifically, we address the question, ‘How should an existing HVAC system modify its operation to benefit from the deployment of PCSs? ’ For example, energy use could be reduced during periods of sparse occupancy by choosing appropriate thermal set points, with each PCS providing the additional offset in thermal comfort required by each occupant. We present the design of a PCS-aware HVAC control strategy based on Model Predictive Control (MPC) that employs a bi-linear thermal model. We use extensive simulations to compare the energy use and comfort offered by our PCS-aware HVAC system with that of a state-of-the-art MPC-based central HVAC system. We study different room layouts and scenarios with full or partial deployment of PCSs. Numerical evaluations show that our system yields significant savings in energy use in both summer and winter, compared both with a state-of-the-art system that does not deploy PCSs and with a similar system that deploys PCSs, but is not aware of them.
The Mechanisms of Mineralized Tissue Resorption by Clast Cells in Relation to Orthodontic Tooth Movement and Root Resorption

Orthodontic tooth movement depends on favorable supporting tissues responding to the forces used during treatment. The tissues involved are the periodontal ligament (PDL), alveolar bone, cementum and dentin. Clast cells play an important role in the process of physiologic remodeling and mineralized tissue responses to external forces. They also play a significant role in unfavorable iatrogenically induced root resorption. Understanding the tissues and cells involved is essential for modulating the biology of orthodontic tooth movement and the prevention of the unwanted side effects of orthodontic treatment.
Both cdc 2 and cdk 2 promote S phase initiation in Xenopus egg extracts

Xenopus egg extracts induce S phase DNA replication in added sperm pronuclei in a highly regulated manner, similar to events in vivo. Removal of cyclin-dependant kinases (cdks) or cdk2 from these extracts using affinity matrices severely inhibits initiation of S phase. We have used p13suc1 beads to remove both cdk2 and cdc2 proteins from egg extracts and developed a method to replace either protein alone to assess their capacity to initiate DNA replication. Re-addition of either cdk2 or cdc2 proteins to depleted extracts, through translation of their respective mRNAs, restimulated replication, judged by both total synthesis and labelling index. An ATP-binding-site mutant cdk2 mRNA (cdk2.R33) failed to stimulate replication and inhibited S phase initiation in mock-depleted extracts. Both human and Xenopus cdc2 mRNAs rescued replication in this system. Human mutant mRNAs have been used to show that the stimulation induced requires cdc2 catalytic activity, though not its mitotically active form. Rescue of replication by p34cdc2 is also observed in extracts depleted of cdks with a cdk2 antibody, which still retain much of their endogenous cdc2 protein. We conclude that newly synthesised p34cdc2, but not the inherited ‘old’ form, can induce S phase and in this form may overlap in function with p33cdk2.
Levshenko T. Toxicologic and Hygienic Characteristics of p-373-2-20; p-5003-ac;p-294-2-35 Polyols and Prognosis of Their Potential Danger for Environment.

Studied the toxic effects polyoxipropylenpolyols in acute and subacute experiments on warm-blooded animals. It is established that they are pertained to the IV hazard class; have polytropic general toxic effect; on the level of toxic doses they influence on the generative function and the genetic apparatus; inhibit and disrupt the interaction between the cellular and humoral immunity.Experiments were performed on adult Wistar white rats, white mouses, guinea pigs, hybrid mouse lines BALB / C, (SBAc57BL) F1, CBA / Lac, and rabbits of the chinchilla race [4-6]. The objects of the investigation were polyoxipropylenthriols with molecular masses 5000M (P-5003-AC), and 370M (P-373-2-20), and polyoxipropylated amine with molecular mass 290M (P-294-2-35). Polyoxipropylenpolyols P-5003-AC, P-373-2-20 and P-294-2-35 in doses of 1/10 and 1/100 DL50 have a toxic effect on the generatic function and the genetic apparatus, and in doses 1/10, 1/100 and 1/1000 DL50 inhibit and disrupt the cooperative interaction of cellular and humoral immunity. In all cases, the dose of 1/10000 DL50 was inoperative, it is equal to 3.23; 3.62 and 1.48 mg / kg of animal weight, respectively, for P-373-2-20, P-5003-AC and P-294-2- 35.
Heuristics for the One-Commodity Pickup-and-Delivery Traveling Salesman Problem

This paper deals with a generalisation of the well-knowntraveling salesman problem (TSP) in which cities correspond to customers providing or requiring known amounts of a product, and the vehicle has a given upper limit capacity. Each customer must be visited exactly once by the vehicle serving the demands while minimising the total travel distance. It is assumed that any unit of product collected from a pickup customer can be delivered to any delivery customer. This problem is calledone-commodity pickup-and-delivery TSP (1-PDTSP). We propose two heuristic approaches for the problem: (1) is based on a greedy algorithm and improved with ak-optimality criterion and (2) is based on a branch-and-cut procedure for finding an optimal local solution. The proposal can easily be used to solve the classical "TSP with pickup-and-delivery," a version studied in literature and involving two commodities. The approaches have been applied to solve hard instances with up to 500 customers.