Miracle-dz/UniFAR-FTUs huggingface dataset:
Shrinkage reduction in perishable food supply chain by means of an RFID-based FIFO management policy

The objective of this paper is to point out how Radio Frequency Identification (RFID) technology can be used to improve the First In First Out (FIFO) policy of fresh products warehouses in the large-scale retail channel. The relatively short shelf life of fresh products forces to maintain a punctual control of the rotation of cases in the warehouse. The implementation of an RFID system enables to real time monitor the supply chain processes an item is subject to; in particular, the present work focuses on the process of shelf replenishment, by moving cases from the backroom to the shop floor. By means of an accurate monitoring of this process, the errors caused by noncompliance with the FIFO policy were pointed out, and the economic savings resulting from the use of RFID technology in that context were evaluated. Results show that the deployment of RFID technology has potential to help manage the FIFO policy of fresh products, thus generating interesting savings for the food supply chain.
Implantable Cardioverter‐Defibrillator Therapy in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy: Predictors of Appropriate Therapy, Outcomes, and Complications

Background Arrhythmogenic right ventricular dysplasia/cardiomyopathy is characterized by ventricular arrhythmias and sudden cardiac death. Once the diagnosis is established, risk stratification to determine whether implantable cardioverter‐defibrillator (ICD) placement is warranted is critical. Methods and Results The cohort included 312 patients (163 men, age at presentation 33.6±13.9 years) with definite arrhythmogenic right ventricular dysplasia/cardiomyopathy who received an ICD. Over 8.8±7.33 years, 186 participants (60%) had appropriate ICD therapy and 58 (19%) had an intervention for ventricular fibrillation/flutter. Ventricular tachycardia at presentation (hazard ratio [HR]: 1.86; 95% confidence interval [CI], 1.38–2.49; P<0.001), inducibility on electrophysiology study (HR: 3.14; 95% CI, 1.95–5.05; P<0.001), male sex (HR: 1.62; 95% CI, 1.20–2.19; P=0.001), inverted T waves in ≥3 precordial leads (HR: 1.66; 95% CI, 1.09–2.52; P=0.018), and premature ventricular contraction count ≥1000/24 hours (HR: 2.30; 95% CI, 1.32–4.00; P=0.003) were predictors of any appropriate ICD therapy. Inducibility at electrophysiology study (HR: 2.28; 95% CI, 1.10–4.70; P=0.025) remained as the only predictor after multivariable analysis. The predictors for ventricular fibrillation/flutter were premature ventricular contraction ≥1000/24 hours (HR: 4.39; 95% CI, 1.32–14.61; P=0.016), syncope (HR: 1.85; 95% CI, 1.10–3.11; P=0.021), aged ≤30 years at presentation (HR: 1.76; 95% CI, 1.04–3.00; P<0.036), and male sex (HR: 1.73; 95% CI, 1.01–2.97; P=0.046). Younger age at presentation (HR: 3.14; 95% CI, 1.32–7.48; P=0.010) and high premature ventricular contraction burden (HR: 4.43; 95% CI, 1.35–14.57; P<0.014) remained as independent predictors of ventricular fibrillation/flutter. Complications occurred in 66 participants (21%), and 64 (21%) had inappropriate ICD interventions. Overall mortality was low at 2%, and 4% underwent heart transplantation. Conclusion These findings represent an important step in identifying predictors of ICD therapy for potentially fatal ventricular fibrillation/flutter and should be considered when developing a risk stratification model for arrhythmogenic right ventricular dysplasia/cardiomyopathy.
Örebro Musculoskeletal Pain Screening Questionnaire Short-Form and STarT Back Screening Tool: Correlation and Agreement Analysis

Study Design. Correlation and agreement analysis. Objective. The objective of this study was to compare the Brazilian Portuguese versions of the Örebro Musculoskeletal Pain Screening Questionnaire Short-Form (ÖMPSQ-short) and the STarT Back Screening Tool (SBST)-Brazil in patients with low back pain and to verify their correlation with disability, kinesiophobia, and pain. Summary of Background Data. The ÖMPSQ-short and the SBST were designed to identify patients at risk of developing pain and disability related to psychosocial factors. Methods. We assessed 130 patients, who answered the ÖMPSQ-short, SBST-Brazil, Roland-Morris disability questionnaire, Tampa scale of kinesiophobia, and Pain Numerical Rating scale. The total scores of the ÖMPSQ-short and the SBST-Brazil were correlated with the other questionnaires. Cross-tabulation and Cohen &kgr; were used to analyze the agreement between the ÖMPSQ-short and the SBST-Brazil for participant classification as low or high risk for involvement of psychosocial factors. Results. The ÖMPSQ-short and the SBST-Brazil presented good correlation between total scores (r = 0.73), good correlation with disability (ÖMPSQ-short: r = 0.72; SBST-Brazil: r = 0.76), and kinesiophobia (ÖMPSQ-short: r = 0.68; SBST-Brazil: r = 0.60) and moderate correlation with pain in the last episode (ÖMPSQ-short: r = 0.39; SBST-Brazil: r = 0.48), in last 2 weeks (ÖMPSQ-short: r = 0.39; SBST: r = 0.43), and current pain (ÖMPSQ-short: r = 0.39; SBST-Brazil: r = 0.31). Participant classification as high or low risk by the two questionnaires showed moderate agreement (&kgr; = 0.49). A total of 83% of participants were classified correctly by the two questionnaires. Conclusion. The ÖMPSQ-short and the SBST-Brazil showed good correlation between total scores and moderate agreement for patient classification in relation to the presence of psychosocial factors. Level of Evidence: 3
The roles of past behavior and health beliefs in predicting medication adherence to a statin regimen

Purpose: Current medication-adherence predictive tools are based on patient medication-taking beliefs, but studying past behavior may now be a more explanatory and accessible method. This study will evaluate if past medication-refill behavior for a statin regimen is more predictive of medication adherence than patient medication-taking health beliefs. Patients and methods: This prospective longitudinal study was implemented in a national managed care plan in the United States. A group of 1433 statin patients were identified and followed for 6 months. Medication-taking health beliefs, collected from self-reported mail questionnaires, and past medication-refill behavior, using proportion of days covered (PDC), were collected prior to 6-month follow-up. Outcomes were measured using categorical PDC variable (of adherence, PDC ≥ 85%, versus nonadherence, PDC < 85%), with model fit estimated using receiver operator characteristic analysis. Results: The area under the receiver operator characteristic curve for past behavior (Az = 0.78) was significantly greater (P < 0.05) than for patient health beliefs (Az = 0.69), indicating that past prescription-refill behavior is a better predictor of medication adherence than prospective health beliefs. Among health beliefs, the factor most related to medication adherence was behavioral intent (odds ratio, 5.12; 95% confidence interval, 1.84 to 15.06). The factor most strongly related to behavioral intent was impact of regimen on daily routine (odds ratio, 3.3; 95% confidence interval, 1.41 to 7.74). Conclusion: Electronic medical records and community health-information networks may make past prescription-refill rates more accessible and assist physicians with managing medication-regimen adherence. Health beliefs, however, may still play an important role in influencing medication-taking behaviors.
The effect of temperature on cardiovascular disease hospital admissions among elderly people in Thai Nguyen Province, Vietnam

Background Projected increases in weather variability due to climate change will have severe consequences on human health, increasing mortality, and disease rates. Among these, cardiovascular diseases (CVD), highly prevalent among the elderly, have been shown to be sensitive to extreme temperatures and heat waves. Objectives This study aimed to find out the relationship between daily temperature (and other weather parameters) and daily CVD hospital admissions among the elderly population in Thai Nguyen province, a northern province of Vietnam. Methods Retrospective data of CVD cases were obtained from a data base of four hospitals in Thai Nguyen province for a period of 5 years from 2008 to 2012. CVD hospital admissions were aggregated by day and merged with daily weather data from this period. Distributed lag non-linear model (DLNM) was used to derive specific estimates of the effect of weather parameters on CVD hospital admissions of up to 30 days, adjusted for time trends using b-splines, day of the week, and public holidays. Results This study shows that the average point of minimum CVD admissions was at 26°C. Above and below this threshold, the cumulative CVD admission risk over 30 lag days tended to increase with both lower and higher temperatures. The cold effect was found to occur 4–15 days following exposure, peaking at a week's delay. The cumulative effect of cold exposure on CVD admissions was statistically significant with a relative risk of 1.12 (95% confidence interval: 1.01–1.25) for 1°C decrease below the threshold. The cumulative effect of hot temperature on CVD admissions was found to be non-significant and was estimated to be at a relative risk of 1.17 (95% confidence interval: 0.90–1.52) for 1°C increase in the temperature. No significant association was found between CVD admissions and the other weather variables. Conclusion Exposure to cold temperature is associated with increasing CVD admission risk among the elderly population.
Assessment of flow‐mediated dilatation in the superficial femoral artery using a sustained shear stress stimulus via calf plantar‐flexion exercise

What is the central question of this study? The aim was to establish the ability of a newly designed leg exercise technique to produce sustained elevations in shear rate that stimulate flow‐mediated dilatation (FMD) in the superficial femoral artery and to determine the repeat trial stability of the FMD response. What is the main finding and its importance? Calf plantar‐flexion exercise can be used to increase shear stress and stimulate FMD in the superficial femoral artery. However, the magnitude of FMD varied systematically when multiple trials were repeated in short succession.
Painting and Language: A Pictorial Syntax of Shapes

In previous articles, the author proposed that paintings can have syntactic rules. In this article he develops his proposal further and shows that shapes act as syntactic elements in the languages of painting styles. He meets Nelson Goodman’s objections to his proposal by showing that shapes meet the criterion of syntactic discreteness proposed by the latter to separate linguistic from other symbolic systems. His approach is to specify style as the domain of a language of painting, to show that style is syntactical and to argue that shapes are the primitive syntactic elements of style. His essay relates current research on the development of syntax for picture-reading machines to the question of syntax for paintings.
Technical note: The effect of the 4‐mm‐collimator output factor on gamma knife dose distributions

We present results of investigations of the clinical significance of variations in the value of the 4‐mm‐collimator output factor, OF4/18. Changes in treatment volume, dose‐volume histograms (DVHs), and isodose distributions were studied, by varying OF4/18 up to 20%. The variations were performed on a sample of clinical patient treatment plans for which the 4 mm collimator was used. Although smaller effects are noted for the prescription isodose line, greater dosimetric changes occur for higher dose regions within the target. PACS number(s): 87.53. –j, 87.52. –g
Mining Techniques for Fraud Detection

The paper presents application of data mining techniques to fraud analysis. We present some classification and prediction data mining techniques which we consider important to handle fraud detection. There exist a number of data mining algorithms and we present statistics-based algorithm, decision tree-based algorithm and rule-based algorithm. We present Bayesian classification model to detect fraud in automobile insurance. Naïve Bayesian visualization is selected to analyze and interpret the classifier predictions. We illustrate how ROC curves can be deployed for model assessment in order to provide a more intuitive analysis of the models.
Astrometric tests of General Relativity in the Solar System: mathematical and computational scenarios

We review the mathematical models available for relativistic astrometry, discussing the different approaches and their accuracies in the context of the modern experiments from space like Gaia and GAME, and we show how these models can be applied to the real world, and their consequences from the mathematical and numerical point of view, with specific reference to the case of Gaia, whose launch is due before the end of the year.
Glucose-6-phosphate dehydrogenase and transketolase modulate breast cancer cell metabolic reprogramming and correlate with poor patient outcome

The pentose phosphate pathway is a fundamental metabolic pathway that provides cells with ribose and NADPH required for anabolic reactions — synthesis of nucleotides and fatty acids — and maintenance of intracellular redox homeostasis. It plays a key role in tumor metabolic reprogramming and has been reported to be deregulated in different types of tumors. Herein, we silenced the most important enzymes of this pathway — glucose-6-phosphate dehydrogenase (G6PD) and transketolase (TKT) — in the human breast cancer cell line MCF7. We demonstrated that inhibition of G6PD, the oxidative branch-controlling enzyme, reduced proliferation, cell survival and increased oxidative stress. At the metabolic level, silencing of both enzymes reduced ribose synthesis. G6PD silencing in particular, augmented the glycolytic flux, reduced lipid synthesis and increased glutamine uptake, whereas silencing of TKT reduced the glycolytic flux. Importantly, we showed using breast cancer patient datasets that expression of both enzymes is positively correlated and that high expression levels of G6PD and TKT are associated with decreased overall and relapse-free survival. Altogether, our results suggest that this metabolic pathway could be subjected to therapeutic intervention to treat breast tumors and warrant further investigation.
Rosenberg Request for Comments : 4168 Cisco Systems Category : Standards Track

This document specifies a mechanism for usage of SCTP (the Stream Control Transmission Protocol) as the transport mechanism between SIP (Session Initiation Protocol) entities. SCTP is a new protocol that provides several features that may prove beneficial for transport between SIP entities that exchange a large amount of messages, including gateways and proxies. As SIP is transport-independent, support of SCTP is a relatively straightforward process, nearly identical to support for TCP.
Cost-effectiveness Analysis of Existing Pedicle Screws Reusing Technique in Extension Revision Operation for Adjacent Segmental Stenosis After Lumbar Posterolateral Fusion

Study Design. Retrospective case-control study. Objective. A cost-effectiveness analysis was performed by comparing patients who received extension revision operations for adjacent segment disease (ASD) reusing the pedicle screws extracted from fused segments with patients who received conventional surgery. Summary of Background Data. ASD often required extension revision surgery, and during extension surgery, pedicle screws may be reused by extracting from the fused segments of primary surgery. Methods. Study examined 37 patients who received extension revision surgery for ASD from January 2003 to December 2013. For the fixation of extended segments during revision operation, in 16 cases the pedicle screws extracted from fused segments were reused (group R), and in 21 cases new pedicle screws were used (group C) as a conventional method. Clinical outcomes were evaluated by means of visual analog scale scores for lumbago and leg pain, and the Korean Oswestry Disability Index. Radiologic outcomes were evaluated from the extent of bone union. The total operating costs in the two groups were compared. Results. Visual analog scale scores for lumbago and leg pain, and the Korean Oswestry Disability Index measured at final follow-up averaged 3.6 and 3.8, and 19.9 in group R, and 3.8 and 3.1, and 21.1 in group C, respectively (P = 0.280, P = 0.387, P = 0.751). For radiologic outcomes, there was one case of nonunion in each group. The cost of surgery was 5332 US dollars in group R, and 6109 US dollars in group C, respectively (P = 0.036). Conclusion. Reusing pedicle screws extracted from the fused segments during extension revision operation for ASD can reduce the cost of surgery, and achieves clinical and radiological results similar to those of the conventional operation. Level of Evidence: 4.
Design of a Gd‐DOTA‐Phthalocyanine Conjugate Combining MRI Contrast Imaging and Photosensitization Properties as a Potential Molecular Theranostic

The design and synthesis of a phthalocyanine – Gd‐DOTA conjugate is presented to open the way to novel molecular theranostics, combining the properties of MRI contrast imaging with photodynamic therapy. The rational design of the conjugate integrates isomeric purity of the phthalocyanine core substitution, suitable biocompatibility with the use of polyoxo water‐solubilizing substituents, and a convergent synthetic strategy ended by the use of click chemistry to graft the Gd‐DOTA moiety to the phthalocyanine. Photophysical and photochemical properties, contrast imaging experiments and preliminary in vitro investigations proved that such a combination is relevant and lead to a new type of potential theranostic agent.
Attribute-based Visual Explanation of Multidimensional Projections

Multidimensional projections (MPs) are key tools for the analysis of multidimensional data. MPs reduce data dimensionality while keeping the original distance structure in the low-dimensional output space, typically shown by a 2D scatterplot. While MP techniques grow more precise and scalable, they still do not show how the original dimensions (attributes) influence the projection’s layout. In other words, MPs show which points are similar, but not why. We propose a visual approach to describe which dimensions contribute mostly to similarity relationships over the projection, thus explain the projection’s layout. For this, we rank dimensions by increasing variance over each point-neighborhood, and propose a visual encoding to show the least-varying dimensions over each neighborhood. We demonstrate our technique with both synthetic and real-world datasets.
Dense Reaction Infiltrated Silicon/Silicon Carbide Ceramics Derived from Wood based Composites

The results of the joint project of the German Aerospace Center and the Technical University of Munich showed, that variation of resin content and bulk density of the wood based composite influences directly the microstructure and properties of the carbon preforms and resulting SiSiC ceramic materials and allow following conclusions: The mass loss during carbonization can be effectively reduced by increasing the content of phenolic resin Higher resin contents and higher bulk densities of wood based composites cause a lower bulk density reduction during carbonization Higher resin contents of wood based composites lead to larger carbon aggregates and thus to more coarsely structured carbon preforms. The consequence is an increased residual carbon content of the resulting ceramic The higher compression of the structure of wood based composites by increasing the bulk density is still obvious in the resulting carbon preforms and leads to smaller pore diameters. Excessive compression causes a deterioration of the pore interconnectivity and infiltration behaviour of the carbon preform Higher bulk densities of the carbon preforms lead to an increased silicon carbide content as long as (1) the maximum theoretical density for the complete conversion of 0.963 g/cm³ is not exceeded, (2) a fine grained structure is retained and (3) a complete and even infiltration is possible. The mechanical strength of the resulting ceramic depends on its structure and phase composition. The strength rises with increasing silicon carbide content and decreases with increasing residual silicon and carbon content as well as with higher porosity The mechanical properties of SiSiC ceramics derived from wood based composites are promising and show a potential for industrial use. Based on the promising mechanical properties of TUM A1 and TUM A2 further investigations will focus on dense reaction infiltrated SiSiC ceramics with silicon carbide contents up to 90 Vol-% without exceeding a residual carbon content of 1 Vol-%. This means increasing successively the bulk density of the carbon preforms and simultaneously retaining a homogeneous and fine grained structure with a sufficiently interconnected pore system. This aim could be reached by the use of further optimized wood fibres in combination with moderate resin contents.
Dosimetric and volumetric changes in the rectum and bladder in patients receiving CBCT‐guided prostate IMRT: analysis based on daily CBCT dose calculation

Delivered dose can be calculated by transferring the planned treatment beams onto the daily CBCT. Bladder and rectum volumetric doses were calculated and correlated to the daily bladder and rectum fullness. Patients for this study underwent hypofractionated prostate IMRT to 70 Gy in 28 fractions. Daily CBCT was utilized for image guidance. A clinically acceptable plan was created using a CTV‐to‐PTV uniform margin of 5 mm. Image fusion was performed to transfer the bladder and rectum contours onto each CBCT. Contours were then edited to match the anatomy of each CBCT. Using the daily treatment isocenter, the planned beams were transferred onto the CBCT and daily and cumulative DVHs calculated. For the results a total of 168 daily CBCTs were evaluated. The bladder was found to be smaller for 74.7% of the 168 daily CBCTs accessed in this study. This reduction in volume correlated to an increase in the cumulative bladder V70 Gy from 9.47% on the planning CT to 10.99% during treatment. V70Gy for the rectum was 7.27% on the planning CT, when all six patients were averaged, and increased to 11.56% on the average of all daily treatment CBCTs. Increases in volumetric rectum dose correlated with increases in rectal volume. For one patient, the rectum and bladder absolute V70 Gy, averaged over the course of treatment, increased by 295% and 61%, respectively. Larger variations in the daily bladder and rectal volume were observed and these correlated to large deviations from the volumetric dose received by these structures. In summary, bladder and rectum volume changes during treatment have an effect on the cumulative dose received by these organs. It was observed that the volumetric dose received by the bladder decreases as the volume of the bladder increases. The inverse was true for the rectum. PACS number(s): 87.55. dk‐, 87.57. Q‐