Miracle-dz/UniFAR-FTUs huggingface dataset:
C-V profiling of ultrashallow junctions using a step-like background doping profile

A novel C-V profiling method that enables profiling of ultrashallow and ultra-abrupt junctions is described. The method takes advantage of a peculiar shape of the C-V characteristic that is obtained with a step-like or other abruptly changing background profile. The method is analytically described and confirmed by MEDICI simulations. A step-like background As profile and an ultrashallow and ultra-abrupt p+ junction were grown by respectively Si and pure boron RPCVD. Using these techniques, junctions with a doping depth of around 7 nm and with a slope of around 2.5 nm/dec were fabricated and measured.
Actin-based motility: from molecules to movement.

Extensive progress has been made recently in understanding the mechanism by which cells move and extend protrusions using site-directed polymerization of actin in response to signalling. Insights into the molecular mechanism of production of force and movement by actin polymerization have been provided by a crosstalk between several disciplines, including biochemistry, biomimetic approaches and computational studies. This review focuses on the biochemical properties of the proteins involved in actin-based motility and shows how these properties are used to generate models of force production, how the predictions of different theoretical models are tested using a biochemically controlled reconstituted motility assay and how the changes in motility resulting from changes to the concentrations of components of the assay can help understand diverse aspects of the motile behavior of living cells.
INTEGRATED OPERATIONS: A PROPOSAL FOR OPERATIONS MANAGEMENT TEACHING AND RESEARCH

This paper, addressed to professors of operations management (om) in research institutions, suggests that the long‐term academic viability of our discipline requires the generation of a theory uniquely associated with the practice of OM. Such a theory will rest on foundations laid by other disciplines, but must find its own unique synthesis that attends to the problems of OM practice. The paper proposes a framework that recognizes physics, social psychology and philosophy as foundational disciplines for an integrative theoryof OM and suggests which concepts from those disciplines may find voice in such a theory.
Media Professionals' Opinions about Interactive Visualizations of Political Polarization during Brazilian Presidential Campaigns on Twitter

Interactive data visualization techniques are an important way to obtain information from large datasets. Data journalism is an emerging area that strongly makes use of such techniques. In this work we investigate the relationship between journalists (and media professionals) in their job routine and data visualization, with the main goal of understanding if these professionals know and use data visualization tools in their job context, as well as if they consider these resources to be important. For this, we present the results of a survey made with journalists and media professionals to analyze how interactive visualizations could help them to get insight or knowledge of such data, and if their use may improve and support these professionals’ activities. The results indicate that visualization and data analysis tools are still not easily accessible by those professionals, and therefore still less influential than they could be. However, most participants considered data visualization a valuable resource in their news production routines. As a contribution, we also identified positive points and understanding gaps of visualizations, as well as the perception of journalists and media professionals about getting information from data visualization.
Low-cost horn with unique radiation to evaluate probe-fed antenna measurement setup

This paper presents a low-cost back-to-back horn antenna in printed circuit board to evaluate an advanced millimeter-wave (mmWave) measurement setup for probe-fed antennas. Compared with conventional antennas with broadside radiation and smooth main beams, this back-to-back horn antenna features two unique characteristics, i.e., omnidirectional radiation and rippled beam at E-plane. These two characteristics significantly increase the measurement difficulties and make this horn antenna as one of the most difficult designs for probe-based measurement. Therefore, this antenna is an ideal candidate to evaluate a mmWave measurement setup for probe-fed antennas, by verifying its measurement capability of return loss, gain, 3D radiation pattern, efficiency, resolution, and dynamic range.
Theoretical Studies on the Mechanism of the Azido-Tetrazole of Azido-s-triazine

The B3LYP/aug-cc-pvDZ level of theory has been applied to the study of the molecular structures, electronic structures and the azido-tetrazole isomerization of 1-azido-s-triazine, 1,3-diazido-s-triazine and 1,3,5-triazido-s-triazine. NBO analysis was applied to investigate the atomic natural charge and stabilization interaction energies among molecules. The results showed that the reaction initially proceeds through the loss of the linearity of the azido group and the approaching of the terminal nitrogen atom of the azide group to the nitrogen atom of the ring. This is followed by an attack of the lone pairs on N atoms in the ring to the azido group, leading to the formation of the N-N bonds. Many factors, including bending of the bond angle, electrostatic attraction, orbital delocalization and the stabilization interaction give rise to a large free energy barrier for the cyclization process. The results also show that the second and third cyclization is relatively easier than the first one.
Problems of landscape and representation in Ibsen's Når vi døde vågner

In his introduction to Henrik Ibsen’s (1936) Når vi døde vågner, Didrik Arup Seip relays a telling exchange between Ibsen and fellow dramatist Gunnar Heiberg regarding the scenography for the 1900 Norwegian National Theatre production of the play. According to Seip (1936): “Ibsen spurte Gunnar Heiberg hvad han syntes om dekorasjonene – ‘Forferdelige,’ svarte Gunnar Heiberg. Da blev Ibsen ‘barsk og sagde med indædt Raseri og høi, hurtig Stemme: Ja jeg synes heller ikke, det ser slig ud paa Hardangervidden [Ibsen asked Gunnar Heiberg what he thought about the scenography – ‘Appalling,’ answered Gunnar Heiberg. Ibsen then became ‘fierce and said with suppressed rage and a loud, rapid voice: Yes, I don’t think it looks like that on the Hardanger plateau either]” (p. 208). This anecdote reveals a conceptual gap between Ibsen’s artistic vision and the possibilities of representing that vision on stage. We see here that Ibsen sought a visual realism that has for the most part become the domain of cinematic rather than theatrical representation in the century after Ibsen’s death. In this article I will discuss the stage directions in Når vi døde vågner as written and as they have been interpreted in the seven productions of the play that have been staged at Norway’s National Theatre. I want to direct attention to the aporia between Ibsen’s text and what theater scholar Michael Issacharoff (1981) calls the “dramatic space” of individual productions of a play. Issacharoff distinguishes between on-stage mimetic space that is made visible to the audience and off-stage diegetic space that is only referenced by the characters. What I have observed is that by prioritizing abstraction of the mimetic space, the major Norwegian twentiethcentury productions of Når vi døde vågner have so disregarded important elements of the original stage directions that a number of serious ruptures in meaning result.
Organization of the Ly-5 gene

A single Ly-5 gene is known to generate a variety of transmembrane glycoprotein isoforms that distinguish various cell lineages and stages of differentiation within the hematopoietic developmental compartment of the mouse. Systems homologous to Ly-5 are known in rats and in humans. The complete exon-intron organization of the Ly-5 gene is described in this report. The Ly-5 gene occupies about 120 kilobases of chromosome 1 and comprises 34 exons, of which 32 (Ex-3 to Ex-34) are protein coding. Ex-1, Ex-2, and parts of Ex-3 and Ex-34 are untranslated. In all cDNA clones examined, either Ex-1 or Ex-2 was represented, but not both, implying that Ex-1 and Ex-2 in Ly-5 mRNA may be mutually exclusive. Primer extension and S1 nuclease protection mapping were used to identify initiation (cap) sites for transcription. The finding of putative cap sites for Ex-1 and Ex-2, and of corresponding TATA-like sequences, suggests the presence of two promoters. In both Ex-1+ and Ex-2+ cDNA clones the next exon is Ex-3, which has a translation-initiating codon. The intron between Ex-3 and Ex-4 is unusually long, about 50 kilobases. Evidence is given that Ex-5, like Ex-6 and Ex-7 (studied previously), is another alternative exon that is selectively programmed, alone or together with Ex-6 or Ex-7 or both, to generate actual or potential Ly-5 isoforms by alternative splicing.
Continuous δ-Opioid Receptor Activation Reduces Neuronal Voltage-Gated Sodium Channel (NaV1.7) Levels through Activation of Protein Kinase C in Painful Diabetic Neuropathy

The NaV1.7 tetrodotoxin-sensitive voltage-gated sodium channel isoform plays a critical role in nociception. In rodent models of diabetic neuropathy, increased NaV1.7 in dorsal root ganglia (DRG) neurons correlates with the emergence of pain-related behaviors characteristic of painful diabetic neuropathy (PDN). We examined the effect of transgene-mediated expression of enkephalin on pain-related behaviors and their biochemical correlates in DRG neurons. Transfection of DRG neurons by subcutaneous inoculation of a herpes simplex virus-based vector expressing proenkephalin reversed nocisponsive behavioral responses to heat, cold, and mechanical pressure characteristic of PDN. Vector-mediated enkephalin production in vivo prevented the increase in DRG NaV1.7 observed in PDN, an effect that correlated with inhibition of phosphorylation of p38 MAPK (mitogen-activated protein kinase) and protein kinase C (PKC). Primary DRG neurons in vitro exposed to 45 mm glucose for 18 h also demonstrated an increase in NaV1.7 and increased phosphorylation of p38 and PKC; these changes were prevented by transfection in vitro with the enkephalin-expressing vector. The effect of hyperglycemia on NaV1.7 production in vitro was mimicked by exposure to PMA and blocked by the myristolated PKC inhibitor 20-28 or the p38 inhibitor SB202190 [4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)1H-imidazole]; the effect of vector-mediated enkephalin on NaV1.7 levels was prevented by naltrindole. The results of these studies suggest that activation of the presynaptic δ-opioid receptor by enkephalin prevents the increase in neuronal NaV1.7 in DRG through inhibition of PKC and p38. These results establish a novel interaction between the δ-opioid receptor and voltage-gated sodium channels.
A Scalable RDF Store Based on HBase Sever Fundătureanu

The exponential growth of the Semantic Web leads to a need for a scalable storage solution for RDF data. In this project, we design a quad store based on HBase, a NoSQL database which has proven to scale out to thousands of nodes. We adopt an Id-based schema and argue why it enables a good trade-off between loading and retrieval performance. We devise a novel bulk loading technique based on HBase coprocessors and we compare it to a traditional Map-Reduce technique. The evaluation shows that our technique does not scale as well as the traditional approach. Instead, with Map-Reduce, we achieve a loading throughput of 32152 quads/second on a cluster of 13 nodes. For retrieval, we obtain a peak throughput of 56447 quads/second.
Analysis of the accuracy of the numerical reflection coefficient of the finite-difference time-domain method at planar material interfaces

This paper presents a rigorous analysis of the numerical error of the reflection coefficient of the finite-difference time-domain (FDTD) algorithm at planar material boundaries. The derived expressions show that the numerical reflection depends on a large number of parameters, such as the grid resolution and the time step, the frequency, the angle, and the polarization of the incident wave. In conclusion, the FDTD algorithm does not accurately fulfil the boundary conditions for the continuity of the fields. The theoretical findings enable the detailed characterization of the field behavior in the grid at material interfaces. The numerical total reflection and the Brewster angle are studied as well as the discretization influences on the specific absorption rate (SAR).
Polyamines in embryogenic cultures of Norway spruce (Picea abies) and red spruce (Picea rubens).

Embryogenic cultures of red spruce (Picea rubens Sarg.) and Norway spruce (Picea abies (L.) Karst. ) were initiated from dissected mature zygotic embryos. The tissues were grown on either proliferation medium or maturation medium. On proliferation medium, the embryogenic tissue continued to produce early stage somatic embryos (organized meristems attached to elongated, suspensor-like cells), whereas on maturation medium fully mature embryos developed from the embryonic tissue. Analysis of polyamines in tissues grown on these two media showed that: (1) both putrescine and spermidine concentrations were always higher in cultures grown on proliferation medium than in cultures grown on maturation medium; (2) in both species, spermidine concentrations declined with time in the tissues grown on maturation medium; and (3) spermine was present in only minute quantities and showed only a small change with time. The presence of difluoromethylornithine in the culture medium had little effect on polyamine concentration, whereas the presence of difluoromethylarginine caused a decrease in putrescine concentrations in both red spruce and Norway spruce tissues grown on proliferation medium or maturation medium.
Preparation of microparticulate β‐glucan from Saccharomyces cerevisiae for use in immune potentiation

Aims: To develop a method for the preparation of an immunologically active, homogeneous, nonaggregated, microparticulate β‐glucan‐containing material from the budding yeast Saccharomyces cerevisiae. Methods and Results: Using a combination of sonication and spray‐drying, a homogeneous preparation of 1–2‐µ diameter β‐glucan‐containing particles was made from alkali‐ and acid‐insoluble yeast cell wall material. This microparticulate β‐glucan remained in suspension longer and, following oral administration at 0·1 mg kg−1 for 14 d, enhanced phagocytosis of mouse peritoneal macrophages significantly better than did aggregated β‐glucan particles. Conclusions: A new sonication and spray‐drying method can be employed to overcome the problem of aggregation of β‐glucan microparticles in aqueous media. Significance and Impact of the Study: A microparticulate form of β‐glucan that remains in suspension longer for pharmaceutical applications and has superior immune potentiation characteristics has been developed.
Surface and core electronic structure of oxidized silicon nanocrystals

Ab initio restricted Hartree-Fock method within the framework of large unit cell formalism is used to simulate silicon nanocrystals between 216 and 1000 atoms (1.6-2.65nm in diameter) that include Bravais and primitive cell multiples. The investigated properties include core and oxidized surface properties. Results revealed that electronic properties converge to some limit as the size of the nanocrystal increases. Increasing the size of the core of a nanocrystal resulted in an increase of the energy gap, valence band width, and cohesive energy. The lattice constant of the core and oxidized surface parts shows a decreasing trend as the nanocrystal increases in a size that converges to 5.28 A in a good agreement with the experiment. Surface and core convergence to the same lattice constant reflects good adherence of oxide layer at the surface. The core density of states shows highly degenerate states that split at the oxygenated (001)-(1 × 1) surface due to symmetry breaking. The nanocrystal surface shows smaller gap and higher valence and conduction bands when compared to the core part, due to oxygen surface atoms and reduced structural symmetry. The smaller surface energy gap shows that energy gap of the nanocrystal is controlled by the surface part. Unlike the core part, the surface part shows a descending energy gap that proves its obedience to quantum confinement effects. Nanocrystal geometry proved to have some influence on all electronic properties including the energy gap.
Jeux de bandits et fondations du clustering

Ce travail de these s'inscrit dans le domaine du machine learning et concerne plus particulierement les sous-categories de l'optimisation stochastique, du online learning et du clustering. Ces sous-domaines existent depuis plusieurs decennies mais ils ont tous recu un eclairage different au cours de ces dernieres annees. Notamment, les jeux de bandits offrent aujourd'huiun cadre commun pour l'optimisation stochastique et l'online learning. Ce point de vue conduit a de nombreuses extensions du jeu de base. C'est sur l'etude mathematique de ces jeux que se concentre la premiere partie de cette these. La seconde partie est quant a elle dediee au clustering et plus particulierement a deux notions importantes : la consistance asymptotique des algorithmes et la stabilite comme methode de selection de modeles.
Discovery of the natural anti‐Gal antibody and its past and future relevance to medicine

This is a personal account of the discovery of the natural anti‐Gal antibody, the most abundant natural antibody in humans, the reciprocal distribution of this antibody and its ligand the α‐gal epitope in mammals and the immunological barrier this antibody has formed in porcine to human xenotransplantation. This barrier has been overcome in the recent decade with the generation of α1,3‐galactosyltransferase gene‐knockout pigs. However, anti‐Gal continues to be relevant in medicine as it can be harnessed for various therapeutic effects. Anti‐Gal converts tumor lesions injected with α‐gal glycolipids into vaccines that elicit a protective anti‐tumor immune response by in situ targeting of tumor cells for uptake by antigen‐presenting cells. This antibody further accelerates wound and burn healing by interaction with α‐gal nanoparticles applied to injured areas and induction of rapid recruitment and activation of macrophages. Anti‐Gal/α‐gal nanoparticle immune complexes may further induce rapid recruitment and activation of macrophages in ischemic myocardium and injured nerves, thereby inducing tissue regeneration and prevention of fibrosis.
Project level effects of gender on contribution evaluation on GitHub

Distributed open source software development has largely turned to GitHub, a pull-based software development collaboration platform. Recent studies have deployed data science techniques on the large datasets available about millions of projects on GitHub. Some research has focused on pull request (PR) acceptance predictors and evidence was found of sexual discrimination among members. In this paper I analyzed the influence of gender on PR acceptance on a project level, comparing different popular projects regarding their discrimination factors. Several projects were identified that have significant differences between male and female PR acceptance rates.
Cardinality Counting Circuit for Real-Time Abnormal Traffic Detection

To resist the growth of abnormal traffic such as P2P, DDoS and Internet worms, this paper discusses a circuit design to realize real-time abnormal traffic detection from broadband networks. Real-time counting of cardinality is the key of the circuit. Although our previous study showed the effectiveness of cardinality counting to detect various abnormal traffic, the slowness of DRAM access prevented us from actually deploying the cardinality counting into backbone network. This paper shows that the use of self-timed pipeline circuit can realize a cardinality counting circuit that can handle up-to 100 Gbps networks by hiding the DRAM access latency.
Regresión logística multinomial

En este articulo se presenta la regresion logistica multinomial como extension multivariante de la regresion logistica binaria clasica, ampliamente utilizada en la investigacion forestal. A partir de la formulacion matematica del modelo estadistico se explica la estimulacion de parametros mediante el metodo de maxima verosimilitud y se establecen los test estadisticos adecuados para la significatividad global del modelo y el efecto de cada regresor. Tambien se calculan los intervalos de confianza asintoticos para los parametros y se mide la calidad del ajuste mediante los coeficientes de determinacion (pseudo-R2) mas ampliamente utilizados. La calidad en la prediccion puede medirse, al igual que en el analisis discriminante, mediante la tabla de clasificacion observados-predichos o mediante validacion externa si se dispone de una muestra alternativa para ese proposito.
Investigation and Physicochemical Characterization of Clarithromycin–Citric Acid–Cyclodextrins Ternary Complexes

ABSTRACT The purpose of this study was to investigate the effect of citric acid (CA) on the complexation of clarithromycin (CLM) with β-cyclodextrin (βCD) in aqueous solutions and in the solid state. A phase solubility study revealed a positive effect of CA on the drug solubility. A Bs-type solubility with an apparent stability constant (Kc) of 102.4 M−1 was obtained for CLM in βCD solution and 161.2 M−1 for CLM in 6 mM βCD solution. Solid ternary complexes were prepared by coevaporation and lyophilization. CLM–βCD–CA interactions were studied in the solid state by differential scanning calorimetry (DSC), infrared spectroscopy, scanning electron microscopy and X-ray diffractometry. A part of the guest molecule was located in the βCD host cavity. The results obtained suggest that the lyophilization method yields a higher degree of amorphous entity than coevaporation.
Accurate automatic visible speech synthesis of arbitrary 3D models based on concatenation of diviseme motion capture data

We present a technique for accurate automatic visible speech synthesis from textual input. When provided with a speech waveform and the text of a spoken sentence, the system produces accurate visible speech synchronized with the audio signal. To develop the system, we collected motion capture data from a speaker's face during production of a set of words containing all diviseme sequences in English. The motion capture points from the speaker's face are retargeted to the vertices of the polygons of a 3D face model. When synthesizing a new utterance, the system locates the required sequence of divisemes, shrinks or expands each diviseme based on the desired phoneme segment durations in the target utterance, then moves the polygons in the regions of the lips and lower face to correspond to the spatial coordinates of the motion capture data. The motion mapping is realized by a key‐shape mapping function learned by a set of viseme examples in the source and target faces. A well‐posed numerical algorithm estimates the shape blending coefficients. Time warping and motion vector blending at the juncture of two divisemes and the algorithm to search the optimal concatenated visible speech are also developed to provide the final concatenative motion sequence. Copyright © 2004 John Wiley & Sons, Ltd.