Miracle-dz/UniFAR-FTUs huggingface dataset:
An Orthotopic Lung Tumor Model for Image-Guided Microirradiation in Rats

Abstract The purpose of this study was to develop a rat orthotopic lung tumor model with a solitary intrapulmonary nodule to study the effects of high-dose radiation. A549-Luc non-small cell lung cancer (NSCLC) cells were implanted into nude rats in the intercostal space between ribs 5 and 6 of the right lung. Bioluminescence and microcomputed tomography (CT) imaging were performed after implantation to confirm the presence of a solitary tumor and to monitor tumor growth. A device using image guidance for localization was developed to facilitate high-precision irradiation in small animals. A pilot irradiation study was performed, and response was assessed by bioluminescence imaging and immunohistochemistry. Radiation response was confirmed through serial bioluminescence imaging, and the strength of the bioluminescence signal was observed to be inversely proportional to dose. Response was also observed by the monoclonal antibody bavituximab, which binds to exposed lipid phosphatidylserine (PS) on tumor vessels. The ability to (1) reproducibly generate solitary tumor nodules in the rat lung, (2) identify and monitor tumor growth by bioluminescence imaging and CT imaging, (3) accurately target these tumors using high doses of radiation, and (4) demonstrate and quantify radiation response using bioluminescence imaging provides significant opportunity to probe the biological mechanisms of high-dose irradiation in preclinical settings.
Extraction of Fluid Movement Related Spectral Features from Seismic Traces

Remote evaluation of the mobility characteristics of a fluid enclosed in the pores of subsurface rocks is an issue of the major interest in the petroleum industry. In a last decade several techniques to perform such an evaluation based on attributes derived from seismic images have been proposed. Although these techniques have foundation in theory and have delivered results of reasonable quality in a number of cases, they are still considered experimental and sparsely used in industry. It is due to the fact that enormous complexity of the recorded seismic data makes any interpretation impossible without a sophisticated procedure of seismic imaging. This procedure in turn introduces significant distortions in the data. The question whether subtle spectral effects characterizing a fluid moving in porous rocks are still observable after seismic imaging remains under debate. It is the question that is investigated in this paper from the signal processing prospective.
Characterization of Pseudomonas aeruginosa mutants with altered piliation

The pilus-specific Pseudomonas aeruginosa bacteriophage P04 was used to select spontaneous mutants of strain PAK which have altered piliation. The largest class of phage-resistant mutants synthesized the pilin polypeptide, but did not assemble pili. These mutants are likely to contain mutations in genes required for pilus assembly and not mutations in the pilin structural gene, as they could not be complemented by a normal copy of the pilin gene. In addition, two alterations in pilin gene transcription were found among the mutants--hyperpiliated mutants which overproduce pilin mRNA, and a mutant with temperature-sensitive pilin gene transcription. We also present a model for the regulation of pilin gene transcription by a feedback mechanism sensitive to the relative rates of pilus assembly and disassembly.
Dynamic management of URL based on object-oriented paradigm

As the World Wide Web is popular, it is in high demand for retrieving the right information. In addition, the amount of information that is available has been increased. A search engine is used to locate information, due to the fact that searching for information from an increased amount of information is difficult. The search engine has started to use robot agents to facilitate easier access to the information. The paper proposes a dynamic URL management technique by using the object oriented paradigm for efficient performance of the robot agent. While URLs are saved in a file or database to decide whether the site is visited or not, this technique creates a URL object and pushes in a hash table. Therefore we can easily compare a new URL to others in a hash table which allows us to save, and insert a new URL if the URL is not in a hash table. This technique has the advantage of saving URL in a unique way. Other useful information about URL also can be stored. If the robot agent is suspended, we can save into files by using object serialization to save the main memory.
On the Power Absorbed and Scattered by an Antenna

We discuss the powers absorbed and scattered by a receiving antenna. Most antennas scatter more than they absorb. Antennas that scatter less power than they absorb are rare, and the few examples that have been presented are all based on numerical optimization. This note presents a simple conceptual model - a partially transparent aperture antenna - which provides physical insight into the case where the scattering is less than the absorption. Finally, we comment on the far field in the forward-scattering direction, noting that the total field actually is increased, although the scatterer blocks the incident field.
Frequência alimentar para juvenis de robalo-peva criados em água doce

Este estudo objetivou verificar qual frequencia alimentar e adequada para juvenis de robalo-peva criados em agua doce. O delineamento utilizado foi o em blocos casualizados, com tres frequencias alimentares (uma, duas e quatro vezes ao dia) e quatro repeticoes, divididas em dois blocos (classes de tamanho de peixes com 0,64 ± 0,21g e 6,12 ± 1,87 g). As unidades experimentais foram tanques-rede de 1 m³, estocados com 30 robalos cada, por 60 dias. Ao fim do periodo experimental os peixes atingiram em media 1,77 ± 0,14 g ou 16,0 ± 2,08 g, dependendo da classe de peso inicial. Os parâmetros zootecnicos de fator de condicao, taxa de crescimento especifico, conversao alimentar aparente, coeficiente de variacao do comprimento e do peso, e sobrevivencia foram submetidos a Analise de Variância e ao teste de Tukey com 5% de probabilidade. Foram detectadas diferencas apenas para o fator de condicao. Ao fim do estudo os robalos alimentados duas vezes ao dia apresentaram maiores valores para o fator de condicao, quando comparados aos peixes alimentados uma unica vez. As medias para os tratamentos de uma, duas ou quatro alimentacoes ao dia foram respectivamente 0,870 ± 0,083; 0,946 ± 0,094 e 0,909 ± 0,087. Para a taxa de crescimento especifico e conversao alimentar, houve tendencia de melhores resultados com o aumento das frequencias de alimentacao. Concluiu-se, nas condicoes deste experimento, que o fornecimento de racao pelo menos duas vezes ao dia para o robalo-peva, criado em agua doce, proporciona um bom desempenho zootecnico e melhor fator de condicao.
The development of the EULAR–OMERACT rheumatoid arthritis MRI reference image atlas

Based on a previously developed rheumatoid arthritis MRI scoring system (OMERACT 2002 RAMRIS), the development team agreed which joints, MRI features, MRI sequences, and image planes would best illustrate the scoring system in an atlas. After collecting representative examples for all grades for each abnormality (synovitis, bone oedema, and bone erosion), the team met for a three day period to review the images and choose by consensus the most illustrative set for each feature, site, and grade. A predefined subset of images (for example, for erosion—all coronal slices through the bone) was extracted. These images were then re-read by the group at a different time point to confirm the scores originally assigned. Finally, all selected images were photographed and formatted by one centre and distributed to all readers for final approval.
Title Altered profile of circulating endothelial progenitor cells inobstructive sleep apnea

Background Obstructive sleep apnea (OSA) is independently associated with endothelial dysfunction, which may be perpetuated by alteration in endothelial repair capacity. Our study evaluates changes in endothelial progenitor cell (EPC) profile in relation to OSA and the role of advanced glycation end-products (AGE) in this relationship. Methods Consecutive Chinese adults undergoing sleep studies, who had no medical illnesses or regular medications, were enrolled. Subjects with morbid obesity or grossly elevated lipoprotein levels were excluded from analysis. Circulating EPC was measured with flow cytometry analysis. Results Seventy-two subjects, 64 % with OSA defined by apnea–hypopnea index (AHI) ≥ 5, were analyzed. CD34+ cell counts were positively correlated with oxygen desaturation index (ODI) (r00.250, p00.041) and duration of oxygen desaturation <90 % (T90) (r00.261, p00.033) and negatively with minimal oxygen saturation (r0−0.247, p00.044) after adjusting for age, glucose, body weight, and smoking status. AGE was positively correlated with indices of OSA severity (AHI, r00.249, p00.042; ODI, r00.244, p00.047; T90, r00.243, p00.047; minimal oxygen saturation, r0−0.251, p00.041) and negatively with CD133+ cells (r0−0.281, p00.021). On stepwise multiple linear regression analysis, minimal oxygen saturation (p00.013) and CD133+ cell counts (p00.029) were found to be significant determinants of AGE level (R00.147). Conclusions Nocturnal hypoxemia in OSA subjects was associated with increase in endothelial cells (CD34+) which may promote vascular repair. Accumulation of AGE in OSA may lead to diminution in early EPC (CD133+) and endothelial repair capacity over time, thus contributing to vascular pathogenesis.
Methodology and error budget for evaluating the MODIS-VIIRS land surface reflectance fundamental climate data record

The land surface reflectance is a fundamental climate data record at the basis of the derivation of other climate data records (Albedo, LAI/Fpar, Vegetation indices) and has been recognized as a key parameter in the understanding of the land-surface-climate processes. In this presentation, we present the validation of the Land surface reflectance used for MODIS and VIIRS data. This methodology uses the 6SV Code and data from the AERONET network. The overall accuracy clearly reaches the MODIS and VIIRS specifications. To understand how to improve the validation, we developed an exhaustive error budget. Results show an impact of the absorption of aerosol and of the fine mode volume concentration. At the end, we discuss about the interest of the indirect and direct method for validation.
Ambient assisted living with dynamic interaction ensembles

Advances in Human Computer Interaction techniques continue to enrich Natural User Interface (NUI) research. While dozens of novel NUI interaction techniques are proposed every year, the potential of the human body’s sensory and motor systems is not yet fully utilized. Hence, new pressing calls have emerged for exploring the potential of the whole body in motion when interacting with real-world pervasive and ubiquitous computing ecosystems (ambient spaces). Given the adoption of NUI paradigm in ambient spaces, users will be increasingly expected to interact with multiple interactions techniques simultaneously. Whilst NUIs provide rich interaction possibilities and alternatives, they also introduce critical challenges for interactive ambient spaces. This dissertation aims to tackle three of these challenges; namely, large-scale dynamic runtime deployment of existing and future interaction techniques; long-term and adequate record-keeping and dissemination practices for interaction techniques; and in-situ adaptation of interaction possibilities. These challenges are often fueled by users’ increased mobility; the increasingly heterogeneity and availability of interaction resources; and the increasing diversity of the physical abilities of many user populations (e.g., elderly users). This dissertation presents a novel approach for adapting the interaction modalities available to a given application at runtime (as deployable interaction plugins). Accordingly, the capabilities and behaviour of an interactive system are optimized to fit the users’ physical abilities, needs, and context. The approach includes a theoretical concept (called Interaction Ensemble) that relies on decoupling the often tight binding between devices, interaction techniques, and applications. A reference implementation (called the STAGE framework) is presented as an evaluation of the concept.
Cloning of the breakpoints of a de novo inversion of chromosome 8, inv (8)(p11.2q23.1) in a patient with Ambras syndrome

Ambras syndrome (AMS) is a unique form of universal congenital hypertrichosis. In patients with this syndrome, the whole body is covered with fine long hair, except for areas where normally no hair grows. There is accompanying facial dysmorphism and teeth abnormalities, including retarded first and second dentition and absence of teeth. In 1993, Baumeister et al. reported an isolated case of Ambras syndrome in association with a pericentric inversion of chromosome 8. Subsequently, another patient with congenital hypertrichosis and rearrangement of chromosome 8 was reported by Balducci et al. (1998). Both of these patients have a breakpoint in 8q22 in common suggesting that this region of chromosome 8 contains a gene involved in regulation of hair growth. In order to precisely determine the nature of the rearrangement in the case of Ambras syndrome, we have used fluorescent in situ hybridization (FISH) analysis. We have cloned the inversion breakpoints in this patient and generated a detailed physical map of the inversion breakpoint interval. Analysis of the transcripts that map in the vicinity of the breakpoints revealed that the inversion does not disrupt a gene, and suggests that the phenotype is caused by a position effect.
ImageRank: A novel sorting algorithm with relevance feedback in application of national costume image retrieval

It is difficult to obtain fairly satisfactory result for national costume images retrieval in real application using existing search engine due to the complexity of visual features and semantic information implied in national costume. Given the fact, a novel sorting algorithm ImageRank is proposed for image retrieval with relevance feedback in this paper, inspired by the PageRank algorithm used by Google Search to rank websites or webpages in their search engine results. ImageRank is realized based on Lucene Image Retrieval (LIRE) toolkit, which is a Java library that provides a simple way to retrieve images and photos based on color and texture characteristics. And it assimilates a good deal of PageRank to accomplish efficient image retrieval by ensuring accurate level of images correlation in resource repository through update the indexical (points-to) relationship timely according to user's behavior dynamically. Experimental results investigate that the performance of ImageRank is better than LIRE. In addition, the conservativeness and convergence of IR value in ImageRank are also verified.
Synopsis: A Distributed Sketch over Voluminous Spatiotemporal Observational Streams

Networked observational devices have proliferated in recent years, contributing to voluminous data streams from a variety of sources and problem domains. These streams often have a spatiotemporal component and include multidimensional features of interest. Processing such data in an offline fashion using batch systems or data warehouses is costly from both a storage and computational standpoint, and in many situations the insights derived from the data streams are useful only if they are timely. In this study, we propose Synopsis, an online, distributed sketch that is constructed from voluminous spatiotemporal data streams. The sketch summarizes feature values and inter-feature relationships in memory to facilitate real-time query evaluations and to serve as input to computations expressed using analytical engines. As the data streams evolve, Synopsis performs targeted dynamic scaling to ensure high accuracy and effective resource utilization. We evaluate our system in the context of two real-world spatiotemporal datasets and demonstrate its efficacy in both scalability and query evaluations.
Deletion Analysis of the Flagellar Switch Protein FliG of Salmonella

ABSTRACT The flagellar motor/switch complex, consisting of the three proteins FliG, FliM, and FliN, plays a central role in bacterial motility and chemotaxis. We have analyzed FliG, using 10-amino-acid deletions throughout the protein and testing the deletion clones for their motility and dominance properties and for interaction of the deletion proteins with the MS ring protein FliF. Only the N-terminal 46 amino acids of FliG (segments 1 to 4) were important for binding to FliF; consistent with this, an N-terminal fragment consisting of residues 1 to 108 bound FliF strongly, whereas a C-terminal fragment consisting of residues 109 to 331 did not bind FliF at all. Deletions in the region from residues 37 to 96 (segments 4 to 9), 297 to 306 (segment 30), and 317 to 326 (segment 32) permitted swarming, though not at wild-type levels; all other deletions caused paralyzed or, more commonly, nonflagellate phenotype. Except for those near the N terminus, deletions had a dominant negative effect on wild-type cells.
The usefulness of F-18 deoxyglucose whole-body positron emission tomography (PET) for re-staging of renal cell cancer.

PURPOSE The use of whole-body PET for re-staging of renal cell carcinoma has not been investigated. The aim of the current study was to examine the diagnostic accuracy and clinical usefulness of whole-body PET imaging for re-staging of renal cell cancer. PATIENTS AND METHODS Clinical PET was performed for re-staging in 36 patients with advanced renal cell cancer. Written reports of imaging studies (including CT, MRI, US, plain film and bone scan), patient history, and extensive chart notes were used to define the clinical stage before PET (pre-PET stage). The written PET report was used to define the clinical stage after PET (PET stage). Reports were used to determine the accuracy of PET for re-staging renal cell cancer and for defining biopsy proven lesions. Clinical parameters and biopsy proven lesions served as reference for the accuracy of PET for re-staging renal cell cancer. RESULTS PET classified the clinical stage correctly in 32/36 patients (89%) and was incorrect in 4/36 (11%) (sensitivity and specificity: 87% and 100%). In 20 patients, 25 suspicious lesions were biopsied within 3.2 +/- 6.7 months of the PET study. Of these, 17 were malignant and 8 were benign. PET correctly classified 21/25 (84%) of the biopsied lesions (sensitivity and specificity: 88% and 75%). CONCLUSION PET re-stages renal cell cancer with a diagnostic accuracy of 89%. Its diagnostic accuracy for classifying biopsy proven anatomic lesions as malignant or benign was 84%. These findings suggest that PET is useful in characterizing anatomic lesions of unknown significance in patients with renal cell cancer.
Hand Gesture Segmentation in Uncontrolled Environments with Partition Matrix and a Spotting Scheme Based on Hidden Conditional Random Fields

Hand gesture segmentation is the task of interpreting and spotting meaningful hand gestures from continuous hand gesture sequences with non-sign transitional hand movements. In real world scenarios, challenges from the unconstrained environments can largely affect the performance of gesture segmentation. In this paper, we propose a gesture spotting scheme which can detect and monitor all eligible hand candidates in the scene, and evaluate their movement trajectories with a novel method called Partition Matrix based on Hidden Conditional Random Fields. Our experimental results demonstrate that the proposed method can spot meaningful hand gestures from continuous gesture stream with 2-4 people randomly moving around in an uncontrolled background.
Mobilizing Senior Citizens in Co-Design of Mobile Technology

This paper disseminates work from the European GiveT 2 Understanding how ad hoc or loosely coupled infrastructures can define a community rather than a formal, organisational structure; and 3 Understanding the nature of mobilization and motivation for participation as processes that continue, and need to be supported, also after completion of the project. These strategies have emerged in the authors' work on mobilization and service sharing, but may apply to a broader context of infrastructuring and ongoing negotiations.
Iterative learning control with applications in energy generation, lasers and health care

Many physical systems make repeated executions of the same finite time duration task. One example is a robot in a factory or warehouse whose task is to collect an object in sequence from a location, transfer it over a finite duration, place it at a specified location or on a moving conveyor and then return for the next one and so on. Iterative learning control was especially developed for systems with this mode of operation and this paper gives an overview of this control design method using relatively recent relevant applications in wind turbines, free-electron lasers and health care, as exemplars to demonstrate its applicability.
Neutrino emission in neutron stars

Neutrino emissivities in a neutron star are computed for the neutrino bremsstrahlung process. In the first part, the electroweak nucleon-nucleon bremsstrahlung is calculated in free space in terms of an on-shell T matrix using a generalized low-energy theorem. In the second part, the emissivities are calculated in terms of the hadronic polarization at the two-loop level. Various medium effects, such as finite particle width, Pauli blocking in the T matrix are considered. Compared to the pioneering work of Friman and Maxwell in terms of (antisymmetrized) one-pion exchange, the resulting emissivity is about a factor 4 smaller at saturation density.
A DSP Based H.264 Dec oder for a Multi-Format IP Set-Top Box

In this paper, the implementation of a digital signal processor (DSP) based H.264 decoder for a multi-format set-top box is described. Baseline and Main profiles are supported. Using several software optimization techniques, the decoder has been fitted into a low-cost DSP. The decoder alone has been tested in simulation, achieving real-time performance with a 600 MHz system clock. Finally, it has been integrated in a multi-format IP set-top box using a commercial development board based on the DSP @ 600 MHz. Tests in a real environment have been performed using this board with good results.
Risk and Protective Factors

What are risk and protective factors? Risk and protective factors are those aspects of a young person’s self and surroundings that correspond to the likelihood of their beginning to use alcohol, tobacco, or other drugs. Risk factors are those characteristics that increase their likelihood of use, while protective factors are the positive aspects of a youth’s life that buffer the negative influences of their risk factors. Research has shown that the more risk factors a young person has, the greater the likelihood of beginning to use, but the presence of protective factors can decrease that likelihood.
Association, Commissural, and Projection Pathways and Their Functional Deficit Reported in Literature

Abstract: This study demonstrates normal white matter structures of the supratentorial system revealed by diffusion tensor imaging. Their anatomic connections and functional significance are discussed in the context of the lesion-induced deficits reported in the literature, which may not fully represent the lesion-induced effects on the white matter function and may not be entirely specific to the tract discussed. Nevertheless, understanding the most common effects of lesions on the functional connectivity provides a framework that we can use in advanced neuroimaging studies, like diffusion tensor imaging, functional magnetic resonance imaging, and positron emission tomography, and in our daily clinical practice.