Miracle-dz/UniFAR-FTUs huggingface dataset:
Towards a representation for multi-viewpoints ontology alignments

In a heterogeneous multi-communities organisation, several communities or groups of users exist with their own viewpoints. Multi-viewpoint ontologies are becoming a crucial aspect in overcoming the limitations of sharing knowledge and keeping the viewpoint of each member of the community. Various ontology alignment approaches have been proposed; however, no system has explored the problem of ontology alignment in the specific context of multi-viewpoints. Moreover, the proposed alignment formats are not sufficient to cover the representation needs of the multi-viewpoints ontology alignments. The key insight into this work is that multi-viewpoints alignment is a set of semantic correspondences between multi-viewpoints ontology elements. Thus, this work focuses on the proposition of a new format allowing the presentation of semantic mapping between multi-viewpoints ontology elements. The extended multi-viewpoints alignment format has the possibility to take into account the different viewpoints' aspects in formal way.
Dietary fibre fermentation in the rat intestinal tract: effect of adaptation period, protein and fibre levels, and particle size

1. The fermentative breakdown of one resistant type of dietary fibre (wheat bran) and one easily-fermented fibre (low-methoxyl pectin) was studied with respect to the length of the adaptation period and fibre level in the diet. The breakdown of the resistant fibre was also studied regarding the protein level in the diet and particle size of the fibre. 2. Prolongation of the adaptation period from 4 to 18 d decreased the faecal dry weight considerably. The excretion of dietary fibre however, was similar, whereas a decrease in faecal nitrogen excretion could be seen. 3. A level of dietary protein of less than 50 g/kg impaired the fermentation of wheat-bran fibre, whereas a level higher than 100 g protein/kg did not further increase the degree of fermentation of the fibre. 4. The particle size did not change the fermentability of the fibre, equal amounts of the main components of coarse and milled bran being excreted in faeces. 5. Two different levels of wheat-bran fibre (48 and 96 g/kg) in the diet did not influence the fibre breakdown. Similar results were obtained with two levels of fibre from low-methoxyl pectin (42 and 84 g/kg), but a tendency towards a decreased percentage of faecal excretion of uronic acids was seen at the lower level of low-methoxyl pectin.
Case management to reduce cardiovascular disease risk in American Indians and Alaska Natives with diabetes: results from the Special Diabetes Program for Indians Healthy Heart Demonstration Project.

OBJECTIVES We evaluated cardiovascular disease (CVD) risk factors in American Indians/Alaska Natives (AI/ANs) with diabetes in the Special Diabetes Program for Indians Healthy Heart (SDPI-HH) Demonstration Project. METHODS Multidisciplinary teams implemented an intensive case management intervention among 30 health care programs serving 138 tribes. The project recruited 3373 participants, with and without current CVD, between 2006 and 2009. We examined data collected at baseline and 1 year later to determine whether improvements occurred in CVD risk factors and in Framingham coronary heart disease (CHD) risk scores, aspirin use, and smoking status. RESULTS A1c levels decreased an average of 0.2% (P < .001). Systolic and diastolic blood pressure, low-density lipoprotein (LDL) cholesterol, and triglyceride levels decreased, with the largest significant reduction in LDL cholesterol (∆ = -5.29 mg/dL; P < .001). Average Framingham CHD risk scores also decreased significantly. Aspirin therapy increased significantly, and smoking decreased. Participants with more case management visits had significantly greater reductions in LDL cholesterol and A1c values. CONCLUSIONS SDPI-HH successfully translated an intensive case management intervention. Creative retention strategies and an improved understanding of organizational challenges are needed for future Indian health translational efforts.
Diagonalized dynamics of robot manipulators

A diagonal equation /spl nu//spl dot/+C(/spl theta/, /spl nu/)=/spl epsiv/ for robot dynamics is developed by combining mass matrix factorization results with classical Lagrangian mechanics. The nonlinear Coriolis term C(/spl theta/, /spl nu/) depends on the joint angles /spl theta/ and the rates /spl nu/ and does no work. The total joint rates /spl nu/=m*(/spl theta/)/spl theta//spl dot/ are related to the relative joint-angle rates /spl theta//spl dot/ by a linear spatial operator m*(/spl theta/) mechanized by a base-to-tip spatially recursive algorithm. <<ETX>>
Reuse Success Strategy Model : An Empirical Study of Factors Involved in the Success of Software Reuse Completed Research Paper

This study examined the relationship between information technology (IT) governance and software reuse success. Software reuse has been mostly an IT problem but rarely a business one. Studies in software reuse are abundant; however, to date, none has a deep appreciation of IT governance. This study demonstrates that IT governance has a positive influence on software reuse success. IT strategy and strategic decision-making process mediate the relationship between IT governance and software reuse success as mediators of the relationship. A sample of over 200 responses from IT professionals and business managers was used in this research. Data analysis was accomplished using confirmatory factor analysis (CFA) and structural equation model (SEM) with AMOS. The findings of this study supported the main causal relationship between effective IT governance and software reuse success. This study confirmed the need for effective IT governance in order to achieve success in software reuse initiatives.
A mutation in subunit B of the DNA polymerase α–primase complex from Novikoff hepatoma cells concomitant with a conformational change and abnormal catalytic properties of the DNA polymerase α–primase complex

Mutated constituents of the DNA replication complex might contribute to the mutational load of the genome during tumor development by impairing DNA synthesis as well as cell cycle–related control of DNA replication. To prove or disprove this hypothesis, we looked for mutations in the cDNA sequences of the four subunits of DNA polymerase α–primase from both highly malignant Novikoff hepatoma cells and regenerating normal rat liver and compared physicochemical and catalytic properties of the DNA polymerase α–primase complexes purified from both sources. Sequence analysis showed two mutations in subunit B from Novikoff cells: one in nucleotide position 855 (CCG→CCA) that did not result in an amino acid exchange and one in position 862 (GTG→ATG) that caused a change of valine to methionine in codon 288. No mutation was found in the three other subunits. The wild‐type and mutated sequences of subunit B were cloned and expressed in vitro. Sedimentation analysis of the expressed polypeptides revealed different sedimentation constants, indicating that the amino acid exchange affected the conformation of subunit B. The analysis of the purified DNA polymerase α–primase complexes showed a sedimentation value that was significantly higher for the enzyme complex from normal liver than for that from Novikoff cells. In addition, DNA polymerase α–primase complexes from Novikoff cells showed higher sensitivity to camptothecin, topotecan, and structurally related compounds (such as (R,S)‐7‐ethyl‐10‐hydroxy camptothecin, 9‐aminocamptothecin, and 10‐hydroxycamptothecin) than the enzyme from normal rat liver. Thus, the amino acid change found in subunit B appears to result in a conformational change of the DNA polymerase α–primase complex from Novikoff hepatoma cells. Whether this mutation influences genetic instability or tumor development needs to be explored. © 2001 Wiley‐Liss, Inc.
Novel Insights of Structure-Based Modeling for RNA-Targeted Drug Discovery

Substantial progress in RNA biology highlights the importance of RNAs (e.g., microRNAs) in diseases and the potential of targeting RNAs for drug discovery. However, the lack of RNA-specific modeling techniques demands the development of new tools for RNA-targeted rational drug design. Herein, we implemented integrated approaches of accurate RNA modeling and virtual screening for RNA inhibitor discovery with the most comprehensive evaluation to date of five docking and 11 scoring methods. For the first time, statistical analysis was heavily employed to assess the significance of our predictions. We found that GOLD:GOLD Fitness and rDock:rDock_solv could accurately predict the RNA ligand poses, and ASP rescoring further improved the ranking of ligand binding poses. Due to the weak correlations (R(2) < 0.3) of existing scoring with experimental binding affinities, we implemented two new RNA-specific scoring functions, iMDLScore1 and iMDLScore2, and obtained better correlations with R(2) = 0.70 and 0.79, respectively. We also proposed a multistep virtual screening approach and demonstrated that rDock:rDock_solv together with iMDLScore2 rescoring obtained the best enrichment on the flexible RNA targets, whereas GOLD:GOLD Fitness combined with rDock_solv rescoring outperformed other methods for rigid RNAs. This study provided practical strategies for RNA modeling and offered new insights into RNA-small molecule interactions for drug discovery.
Amplification of sub-100-TW femtosecond pulses by shifted amplifying Nd:glass amplifiers: theory and experiments.

We show that powerful femtosecond pulses can be obtained by use of a series of amplifying media with shifted but overlapping narrow gain bandwidth. This concept, based on chirped-pulse amplification in Nd:glass amplifiers, permits the generation of sub-100-TW pulses with durations shorter than 300 fs. Experimental gain narrowing and phase distortion are found to be in good agreement with theory.
a Robust Descriptor Based on Spatial and Frequency Structural Information for Visible and Thermal Infrared Image Matching

Abstract. Due to the differences of imaging principles, image matching between visible and thermal infrared images still exist new challenges and difficulties. Inspired by the complementary spatial and frequency information of geometric structural features, a robust descriptor is proposed for visible and thermal infrared images matching. We first divide two different spatial regions to the region around point of interest, using the histogram of oriented magnitudes, which corresponds to the 2-D structural shape information to describe the larger region and the edge oriented histogram to describe the spatial distribution for the smaller region. Then the two vectors are normalized and combined to a higher feature vector. Finally, our proposed descriptor is obtained by applying principal component analysis (PCA) to reduce the dimension of the combined high feature vector to make our descriptor more robust. Experimental results showed that our proposed method was provided with significant improvements in correct matching numbers and obvious advantages by complementing information within spatial and frequency structural information.
Vascular changes associated with deoxycorticosterone-NaCl-induced hypertension.

Rats were injected with deoxycorticosterone (DOC) and salt was added to the drinking water (DOC/NaCl) for 3 weeks. Approximately half of the animals became hypertensive (DOC-H), whereas the remainder showed no increase in blood pressure (DOC-N) compared to age-matched, untreated controls. Morphometric analysis of the alterations in the arteries of the mesenteric bed was carried out in vessels fixed at maximum relaxation. Alterations were observed in the arteries, some of which were related to hypertension, but not to treatment, and some were due to treatment alone. The alterations within the arteries of the mesenteric bed depended in part on the type of artery, i.e. elastic, muscular or arteriolar. An increase in lumen area, in intimal area, and in the area of the media was seen in all types of arteries from DOC-H, but not in either group of normotensive animals. The medial hypertrophy was positively correlated with the increase in blood pressure; and was due to an increase in the number of smooth muscle cell layers in the elastic and muscular arteries, and probably to smooth muscle cell hypertrophy in the arterioles. The adventitial area was increased only in the elastic and muscular arteries. Endothelial injury, degeneration of the basement membrane, loss of heparan sulfate proteoglycan and intimal edema was observed in all the DOC/NaCl-treated animals, but was more severe in those which were also hypertensive. Hypertrophy of the heart and kidneys were observed in both normotensive and hypertensive DOC/NaCl-treated animals. These data indicate that changes in the rat cardiovascular system can be induced by DOC/NaCl treatment in the absence of hypertension, but also that hypertension is associated with specific arterial structural alterations, which vary according to the type of artery.
Effects of Low-Temperature Acclimation and Oxygen Stress on Tocopheron Production in Euglena gracilis Z

The effects of low-temperature acclimation and oxygen stress on tocopheron production were examined in the unicellular phytoflagellate Euglena gracilis Z. Cells were cultured photoheterotrophically at 27.5 � 1�C with 5% carbon dioxide-95% air and 740 microeinsteins m−2 s−1 (photosynthetically active radiation) and served as controls. Low-temperature acclimation (12.5 � 1�C) and high-oxygen stress (5% carbon dioxide-95% oxygen) were individually examined in the mass culturing of the algae. Chromatographic analyses demonstrated a six-to sevenfold enhancement of α-tocopherol production in temperature-stressed cells, along with a concomitant decline in the levels of α-tocotrienol and the absence of other tocopherol homologs. Oxygen-stressed cultures demonstrated the presence of high levels of α-tocopherylquinone; α-tocopheron and its homologs and precursors were absent or declined markedly. These findings are discussed in terms of the feasibility of microbial production of natural tocopherols. In addition, these results lend themselves to speculation regarding the biological role(s) of tocopherols as antioxidants and free radical scavengers in reducing photo-induced oxidative damage or lipid peroxidation toxicities or both in photosynthetically active E. gracilis Z.
Towards service-based approach: building huge software architectural design

Software architecture, as a discipline, draws vocabulary like rules, paradigm, pattern that help to build software systems. In this paper we first provide an introduction to the emerging field of software architecture. Many software architecture approaches were introduced; they draw different paths and methodologies to build software systems. This paper forms a survey for some of these approaches with a focus on the decomposition approach in terms of requirements and data-attributes. In this paper we will discuss a new formal service-based software decomposition approach. This approach consists of a micro-phased process. We begin by considering the front-end services, the common and modern architectural styles upon which many systems are currently based; we focus on their business profiles, non-atomic business data-items and business rules. Our proposed approach represents the first and crucial design stage in the software engineering process. It consists of building the overall software architectures that could be represented as an oriented and purposed graph. At the end, we demonstrate that the process is plausible and easy to apply. We also state that micro-phases may be reiterated and executed without strict ordering. Meta-modelling and computerising such approach represents our future works.
Characterization of sheep populations of Kenya using microsatellite markers : implications for conservation and management of indigenous sheep populations

Indigenous sheep of Kenya are very important to resource-poor farmers and pastoralists. They have over time adapted to the harsh environmental conditions of the arid and semi-arid lands where they are faced with challenges of persistent droughts, diseases, conflicts and poor nutrition, yet show resistance to gastrointestinal nematodes. In recent years, these indigenous sheep populations have been crossbred indiscriminately to exotic breeds particularly the Dorper. A study was undertaken to determine the level of genetic diversity and relatedness between the various sheep populations and breeds of Kenya. This paper reports results on the genetic diversity and admixture observed using microsatellite DNA markers.
Revisiting the Agung 1963 volcanic forcing – impact of one or two eruptions

Abstract. In 1963 a series of eruptions of Mt. Agung, Indonesia, resulted in the third largest eruption of the 20th century and claimed about 1900 lives. Two eruptions of this series injected SO2 into the stratosphere, which can create a long-lasting stratospheric sulfate layer. The estimated mass flux of the first eruption was about twice as large as the mass flux of the second eruption. We followed the estimated emission profiles and assumed for the first eruption on 17 March an injection rate of 4.7 Tg SO2 and 2.3 Tg SO2 for the second eruption on 16 May. The injected sulfur forms a sulfate layer in the stratosphere. The evolution of sulfur is nonlinear and depends on the injection rate and aerosol background conditions. We performed ensembles of two model experiments, one with a single eruption and a second one with two eruptions. The two smaller eruptions result in a lower sulfur burden, smaller aerosol particles, and 0.1 to 0.3 Wm−2 (10 %–20 %) lower radiative forcing in monthly mean global average compared to the individual eruption experiment. The differences are the consequence of slightly stronger meridional transport due to different seasons of the eruptions, lower injection height of the second eruption, and the resulting different aerosol evolution. Overall, the evolution of the volcanic clouds is different in case of two eruptions than with a single eruption only. The differences between the two experiments are significant. We conclude that there is no justification to use one eruption only and both climatic eruptions should be taken into account in future emission datasets.
Does area-based social capital matter for the health of Australians? A multilevel analysis of self-rated health in Tasmania.

BACKGROUND Material circumstances and collective psychosocial processes have been invoked as potential explanations for socioeconomic inequalities in health; and, linking social capital has been proposed as a way of reconciling these apparently opposing explanations. METHODS We conducted multilevel logistic regression of self-rated health (fair or poor vs excellent, very good, or good) on 14 495 individuals living within 41 statistical local areas who were respondents to the 1998 Tasmanian Healthy Communities Study. We modelled the effects of area-level socioeconomic disadvantage and social capital (neighbourhood integration, neighbourhood alienation, neighbourhood safety, social trust, trust in public/private institutions, and political participation), and adjusted for the effects of individual characteristics. RESULTS Area-level socioeconomic disadvantage was associated with poor self-rated health (beta = 0.0937, P < 0.001) an effect that was attenuated, but remained significant, after adjusting for individual characteristics (beta = 0.0419, P < 0.001). Social trust was associated with a reduction in poor self-rated health (beta = -0.0501, p = 0.008) and remained significant when individual characteristics (beta = -0.0398, P = 0.005) were included. Political participation was non-significant in the unadjusted model but became significant when adjusted for individual characteristics (beta = -0.2557, P = 0.045). The effects of social trust and political participation were attenuated and became non-significant when area-level socioeconomic disadvantage was included. CONCLUSION Area-based socioeconomic disadvantage is a determinant of self-rated health in Tasmania, but we did not find an independent effect of area-level social capital. These findings suggest that in Tasmania investments in improving the material circumstances in which people live are likely to lead to greater improvements in population health than attempts to increase area-level social capital.
FREQUENT RESIDENTIAL RELOCATIONS CUMULATIVELY ACCELERATE MENARCHEAL TIMING IN A SAMPLE OF ENGLISH ADOLESCENT GIRLS

Summary Childhood adversity has been associated with accelerated menarcheal and reproductive timing in females. The relationship between family- and neighbourhood-level measures of childhood adversity, menarcheal timing and intended reproductive timing was investigated in a sample of 354 English adolescent girls. The data were collected from March to June 2012. In total 90 of the participants had reached menarche. Frequent residential relocations increased the likelihood of reaching menarche (HR 1.11; 95%CI 1.02–1.22). Girls who had moved house one to four times or five or more times, were respectively, more than twice (HR 2.14; 95%CI 1.23–3.73) and more than three times (HR 3.20; 95%CI 1.44–7.10) as likely to have reached menarche than girls who had never moved house. Frequent residential relocations were associated with stepfather co-residence, increased number of half/stepsiblings and reduced feelings of family support. Menarche was also accelerated by the presence of half/stepsisters. There was no relationship between menarcheal timing and intended reproductive timing. Frequent residential relocations may indicate instability in a young person's life, which is often outside of their control. Extending childhood adversity measures to include residential relocations could be important in better understanding the role early life events play in accelerating menarche.
Steering the Craft: UI Elements and Visualizations for Supporting Progressive Visual Analytics

Progressive visual analytics (PVA) has emerged in recent years to manage the latency of data analysis systems. When analysis is performed progressively, rough estimates of the results are generated quickly and are then improved over time. Analysts can therefore monitor the progression of the results, steer the analysis algorithms, and make early decisions if the estimates provide a convincing picture. In this article, we describe interface design guidelines for helping users understand progressively updating results and make early decisions based on progressive estimates. To illustrate our ideas, we present a prototype PVA tool called InsightsFeed for exploring Twitter data at scale. As validation, we investigate the tradeoffs of our tool when exploring a Twitter dataset in a user study. We report the usage patterns in making early decisions using the user interface, guiding computational methods, and exploring different subsets of the dataset, compared to sequential analysis without progression.
Analysis of the  $N$ -Cell Single Phase MMC Natural Balancing Mechanism

This paper pertains to the analysis of natural balancing properties of an N-cell modular multilevel converter under phase-shifted pulse width modulation control schemes. The key enabling feature for the natural balancing analysis is a set of linear transformations of the input space and state space of the overall system. In the transformed space, we use frequency domain methods to describe the self-balancing properties of the converter. The crux of our proposal is showing that all the cell capacitor voltages converge exponentially fast to a common level; hence achieving natural balancing. The accuracy of the transformed model is verified through comparison with a detailed time-domain simulation of the original system.