Miracle-dz/UniFAR-FTUs huggingface dataset:
A Contribuição da Produção Científica em Marketing para as Ciências Sociais

Marketing researchers often employ bibliometric analysis to assess the importance of scientific production in the field, but few studies have examined its influence outside the discipline itself, particularly in the social sciences with which it maintains an interdisciplinary relationship. This study aimed to fill this knowledge gap by analyzing citations of the eleven leading Marketing journals in the top journals of the closest social sciences – Management, Economy and Finance, Psychology, Sociology and Anthropology – and identifying the articles, journals and subjects which have had more impact in these areas. The subjects were constructed by clustering article keywords, and the results were interpreted by means of network analysis and cross-tabulation. The results show that, although the overall contribution of the discipline is relatively small, certain topics have been objects of interest in each social science. Furthermore, the discipline's contribution is polarized, providing Management with methodology and articles of managerial and strategic natures, while providing other areas mainly with articles in Consumer Behavior. Based on the insights obtained, the scientific status of Marketing production is discussed, as well as the avenues for increasing the relevance of the discipline.
Structural basis for S-adenosylmethionine binding and methyltransferase activity by mitochondrial transcription factor B1

Eukaryotic transcription factor B (TFB) proteins are homologous to KsgA/Dim1 ribosomal RNA (rRNA) methyltransferases. The mammalian TFB1, mitochondrial (TFB1M) factor is an essential protein necessary for mitochondrial gene expression. TFB1M mediates an rRNA modification in the small ribosomal subunit and thus plays a role analogous to KsgA/Dim1 proteins. This modification has been linked to mitochondrial dysfunctions leading to maternally inherited deafness, aminoglycoside sensitivity and diabetes. Here, we present the first structural characterization of the mammalian TFB1 factor. We have solved two X-ray crystallographic structures of TFB1M with (2.1 Å) and without (2.0 Å) its cofactor S-adenosyl-L-methionine. These structures reveal that TFB1M shares a conserved methyltransferase core with other KsgA/Dim1 methyltransferases and shed light on the structural basis of S-adenosyl-L-methionine binding and methyltransferase activity. Together with mutagenesis studies, these data suggest a model for substrate binding and provide insight into the mechanism of methyl transfer, clarifying the role of this factor in an essential process for mitochondrial function.
Colombian forensic genetics as a form of public science: The role of race, nation and common sense in the stabilization of DNA populations

This article examines the role that vernacular notions of racialized-regional difference play in the constitution and stabilization of DNA populations in Colombian forensic science, in what we frame as a process of public science. In public science, the imaginations of the scientific world and common-sense public knowledge are integral to the production and circulation of science itself. We explore the origins and circulation of a scientific object – ‘La Tabla’, published in Paredes et al. and used in genetic forensic identification procedures – among genetic research institutes, forensic genetics laboratories and courtrooms in Bogotá. We unveil the double life of this central object of forensic genetics. On the one hand, La Tabla enjoys an indisputable public place in the processing of forensic genetic evidence in Colombia (paternity cases, identification of bodies, etc.). On the other hand, the relations it establishes between ‘race’, geography and genetics are questioned among population geneticists in Colombia. Although forensic technicians are aware of the disputes among population geneticists, they use and endorse the relations established between genetics, ‘race’ and geography because these fit with common-sense notions of visible bodily difference and the regionalization of race in the Colombian nation.
Characterization and Problem Detection of Routing Policy Configurations

The current Internet routing landscape presents a number of challenges, especially in the configuration of routing policies. There have been numerous proposals to tackle the misconfiguration problem: configuration checking, policy language (re)design, and clean-slate routing architecture. In this paper, we present an analysis of routing policies and a misconfiguration detection mechanism. With an operational perspective, we first present a study on the configuration and evolution of routing policies, using data from three different types of networks. Our results show that configurations are changed frequently and mostly incrementally. We found that the most commonly used and changed commands are related to route tagging and filtering, and there are substantial amount of duplication in policy configurations within a network. More interestingly, based on these results, we develop a data mining method to find inconsistencies in a network’s configurations of routing policies. Our method is able to detect local, network-specific rules automatically, and differs from existing approaches that are based on universally applicable rules. In our evaluation, we found 30 confirmed errors and 29 warnings in three networks. More than half of the errors are related to route tagging. Our findings show that the next generation configuration language and routing platform should be sufficiently flexible to allow a network to express and frequently modify its route tagging, yet restrictive enough as this aspect is often misconfigured.
Sleep movements in teethgrinders.

To investigate the nocturnal motor activity associated with teethgrinding, 12 patients and 12 controls were recorded during sleep with the masseter muscle electromyogram (EMG) and the static charge-sensitive bed movement sensor. The frequency of body movements per hour was 21.4 in the teethgrinders and 14.0 (P less than .05) in the control group. The movement time was 87.4 seconds per hour in the teethgrinders and 55.2 seconds per hour (P less than .01) in the controls. The differences were most obvious in the body movements with temporal association to EMG elevation during the first stage of sleep. The number of isolated EMG elevations showed great interindividual variation and did not differ between groups. The teethgrinders complained more frequently of delayed sleep onset and daytime tiredness. The data suggest that the motor disturbance of teethgrinding is not limited to masticatory muscles but is manifested also as increased general body movement activity.
A Novel Spatially Correlated Multiuser MIMO Channel Modeling: Impact of Surface Roughness

A novel approach for modeling multiuser multiple-input and multiple-output (MIMO) channels is proposed. Here, the scatterers are modeled as random rough surfaces: Any point on rough surfaces scatters the incident wave into any given direction with certain probability. This leads to correlation across different spatially distributed users. The paper derives closed form expressions for the intra-user (point-to-point) and inter-user (multiuser) correlation of pair-wise channel coefficients. It is observed that the distance of users relative to the scatterer surfaces as well as the degree of roughness impact the correlation region. The technique is applied to both non-line-of-sight (NLOS) and line-of-sight (LOS) scenarios. It is observed that LOS signals drastically boost the correlation of the channel coefficients.
Dynamic reconfiguration of distributed programs

A general framework is developed for reconfiguring applications dynamically, where developers may alter the application without loss of service. After presenting the overall framework within which reconfiguration is possible, a description is given of the formal approach for programmers to capture the state of a process abstractly. An environment to support experimentation with dynamic reconfiguration is then described. <<ETX>>
Engagements with Engagement

I will briefly sketch what I see as the genealogy of ‘community engagement’ in the South African academy. It does not claim to be a history, only a schematic trajectory, and it will be partial. Nevertheless, hopefully it can indicate in what ways ‘engagement’ as a value has been taken up by the academy, and perhaps offer some pointers as to where it might go in future.
Towards a fair and efficient downlink bandwidth distribution in XG-PON frameworks

Fairness assurance in modern access networks constitutes a focal point of interest since it dramatically affects the quality of the provided services to the final users. Traffic balancing entails fair bandwidth distribution along with efficient service provisioning, inaugurating a challenging tradeoff between the system throughput and fairness. In this paper, the downlink scheduling effectiveness in modern passive optical networks (PONs) is examined, adopting the ten-gigabit passive optical network (XG-PON) architecture deployed in a tree topology. Considering that the tree topology implies a broadcast nature of data delivering in the downlink direction, the tradeoff between the efficiency and fairness becomes even more compelling, bearing in mind that the distance the broadcast data propagate between the source and users' destination is highly differentiated. In order to remedy this situation two effective scheduling schemes are proposed, namely the shortest propagation processing time (SPPT) and the shortest weighted propagation processing time (SWPPT). Both algorithms are extensively assessed, while the obtained results indicate that the proposed algorithms assure a fair and effective downlink schedule.
Creative Teenage Students: What Are They Telling Us About Their Experiences in (and Around) Our High Schools?

This article highlights various approaches for accommodating and promoting creativity in high school students. Although in the past studies have addressed fostering creativity in our educational systems, few have sought the informative voice of the young creators themselves. The focus of the present study is primarily on environmental determinants of creativity as perceived by 13 (7 male, 6 female) creative seniors selected from a Canadian metropolitan high school. A qualitative study guided by an interactionist model of creative behavior (Woodman & Schoenfeldt, 1989), the present research design adheres most closely to the social constructionist interpretation and application of the grounded theory method as outlined by Charmaz (1990). Insights from 13 interviews and several field observations are divided into three sections. First, identified creative individuals are presented. Then emergent themes relevant to educational systems are examined, and finally, implications and suggestions are discussed.
Content based automatic zooming: viewing documents on small displays

We present an automatic zooming technique that leverages content analysis for viewing a document page on a small display such as a mobile phone or PDA. The page can come from a scanned document (bitmap image) or an electronic document (text and graphics data plus metadata). The page with text and graphics is segmented into regions. For each region, a scale-distortion function is constructed based on image analysis of the signal distortion that occurs at different scales. During interactive viewing of the document, as the user navigates by moving the viewport around the page, the zoom factor is automatically adjusted by optimizing the scale-distortion functions of the regions visible in the viewport.
A Comparison of Substance Use Behaviors of Hispanic Men by Sexual Orientation.

BACKGROUND/SIGNIFICANCE Substance use is a public health concern in the United States. Hispanic men in the United States experience disproportionate rates of substance use when compared to other ethnic groups. Previous research with the general population of Hispanic men has identified factors that are related and may contribute to substance use. In addition, Hispanic men who have sex with men (HMSM) may experience additional social factors that may result in substance use. Despite the body of research on substance use among Hispanic men, no study to date has compared the substance use behaviors of Hispanic men by sexual orientation. OBJECTIVES The purpose of this study was to compare the substance use behaviors of Hispanic men by sexual orientation. METHODS A cross-sectional descriptive design was used to collect data from 164 community-dwelling Hispanic men (i.e., 77 heterosexual men and 87 HMSM) who resided in the South Florida area. Participants completed standardized measures of substance use and demographic characteristics. RESULTS Findings suggested that heterosexual men had higher rates of substance use when compared to MSM. No differences were found among the two groups of men in terms of alcohol intoxication. Religion, education, and income were not predictors of substance use. When health insurance status was controlled, MSM were less likely to report substance use. IMPLICATIONS As a population, Hispanic men continue to experience health disparities in terms of substance use. Because substance use renders Hispanic men at risk for other health issues, more research is needed to understand the co-occurring health disparities experienced by Hispanic men who reside in the United States.
Linking Stakeholder Literature and System Dynamics: Opportunities for Research

The research interest in the field of stakeholder identification, analysis and salience is growing. Stakeholder theories are being proposed and experts in the field are debating over the acceptability of these theories. Starting from the classic stakeholder literature, the paper explores different theories, applications and dynamics of stakeholders available in the literature. The paper concludes that the system dynamics methodology can contribute to understanding the dynamics of stakeholders.
Using relative costs in workflow scheduling to cope with input data uncertainty

Grids and clouds are utilized for the execution of applications composed of dependent tasks, usually modeled as workflows. To efficiently run the application, a scheduler must distribute the components of the workflow in the available resources using information about duration of tasks and communication between tasks in the workflow. However, such information may be subject to imprecisions, thus not reflecting what is observed during the execution. In this paper we propose a simple way of representing the costs of the components in a workflow in order to reduce the impact of uncertainties introduced by wrong estimations, and also to ease the application specification for the user. Evaluation shows that the use of relative costs in tasks and dependencies can improve in many cases the resulting schedule when compared to cases where the input data carries an uncertainty of 20% and 50%.
Long‐term clinical experience with weekly interferon beta‐1a in relapsing multiple sclerosis

Post‐marketing surveillance studies are needed to assess the long‐term safety, compliance and clinical efficacy of interferon beta‐1a (IFNβ‐1a) therapy in multiple sclerosis (MS) patients. The goals of this study were to (i) assess the safety, compliance and clinical efficacy of long‐term intramuscular (i.m.) IFNβ‐1a therapy in a large cohort of patients, and (ii) suggest possible predictors of therapeutic response. A total of 255 patients were included in the study. Mean time on therapy was 31.7 ± 19.3 months. Within 3 years, 31% of patients discontinued treatment, mainly for disease activity. No significant sustained blood analysis alteration was observed over time, apart from a decrease of cholesterol levels. After 3 years of treatment, mean Expanded Disability Status Scale (EDSS) scores increased by 0.4 points compared with baseline. The mean annual relapse rate was reduced compared with baseline. Patients with ≤2 relapses in the previous 2 years and with baseline EDSS scores of ≤2 had a longer estimated time to first relapse and to progression and first relapse, respectively. These results confirm the safety and suggest a sustained effectiveness of i.m. IFNβ‐1a, extending the reported follow‐up period to 6.3 years, and hypothesize the presence of possible predictors of clinical outcome.
Préparation des PME familiales belges à la transmission et impact sur la performance

Une large litterature conceptuelle met en evidence les difficultes eprouvees lors de la transmission des entreprises familiales a la generation suivante. Ces developpements theoriques ont ete valides par de nombreuses etudes empiriques, meme s’il subsiste des debats contradictoires. Les objectifs de cette recherche sont de determiner si la preparation de la transmission a une influence sur la performance des PME familiales et si ces PME se heurtent a moins de problemes. Une enquete, realisee aupres de 2 000 PME, a permis de relever 159 transmissions et de collecter les informations concernant la transmission. Cet article utilise la methodologie du pairage statistique de maniere a comparer les performances de PME familiales preparees a la transmission a celles d’homologues non preparees. Les resultats obtenus ne permettent pas de montrer que les PME familiales preparees sont significativement plus performantes. Les resultats montrent neanmoins une evolution des performances des PME non familiales apres la transmission (observee sur trois ans) encore plus negative en cas de non-preparation.
ANXIOLYTIC ACTIVITY OF ALOE VERA (L.) BURM.F TESTED IN RODENTS

Aloe vera was evaluated for CNS activities in mice and different behavioral activities for anxiety and depression were tested on Exploratory activity, Open field test, Swimming – induced Depression test, Stationary Rod, Cage Crossing and Inclined Plane test. Aloe vera was administered orally in both sexes of mice and was found to cause significant depression in general as well as exploratory behavioral profiles. The results revealed that Aloe vera caused reduction of Exploratory and Locomotor activities along with the significant decrease in traction in an inclined plane test. The results suggest that Aloe vera may have anxiolytic potential with sedative action.
Cardiovascular Consequences of Obesity and Type 2 Diabetes Exercise training promotes cardioprotection through oxygen-sparing action in high fat-fed mice

J. Lund, A. D. Hafstad, N. T. Boardman, L. Rossvoll, N. P. Rolim, M. S. Ahmed, G. Florholmen, H. Attramadal, U. Wisløff, T. S. Larsen, and E. Aasum Cardiovascular Research Group, Department of Medical Biology, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway; K. G. Jebsen Center of Exercise in Medicine, Department of Circulation and Medical Imaging, Faculty of Medicine, Norwegian University of Science and Technology and Saint Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; and Institute for Surgical Research, Department of Cardiology, Center for Heart Failure Research, Oslo University Hospital-Rikshospitalet, University of Oslo, Oslo, Norway
Total flavones of Abelmoschus manihot improve diabetic nephropathy by inhibiting the iRhom2/TACE signalling pathway activity in rats

Abstract Context: Total flavones extracted from Abelmoschus manihot L. (Malvaceae) medic (TFA) have been proven clinically effective at improving renal inflammation and glomerular injury in chronic kidney disease (CKD). Objective: This study evaluated the function of TFA as an inhibitor of iRhom2/TACE (tumour necrosis factor-α converting enzyme) signalling and investigated its anti-DN (diabetic nephropathy) effects in a DN rat model. Materials and methods: In vitro, cells were treated with 200 μg/mL advanced glycation end products (AGEs), and then co-cultured with 20 μg/mL TFA for 24 h. Real time PCR, western blotting and co-immunoprecipitation assays were performed. In vivo, DN was induced in 8 week old male Sprague-Dawley rats via unilateral nephrectomy and intraperitoneal injection of streptozotocin, then TFA were administered to rats by gavage for 12 weeks at three different doses (300, 135 and 75 mg/kg/d). 4-Phenylbutanoic acid (2.5 mg/kg/d) was used as a positive control. Results: IC50 of TFA is 35.6 μM in HK2 and 39.6 μM in HRMC. TFA treatment (20 μM) inhibited the activation of iRhom2/TACE signalling in cultured cells induced by AGEs. LD50>26 g/kg and ED50=67 mg/kg of TFA in rat by gavage, TFA dose-dependently downregulated the expression of proinflammatory cytokines and exerted anti-inflammatory effects significantly though inhibiting the activation of iRhom2/TACE signalling. Discussion and conclusions: Our results show that TFA could dose-dependently ameliorate renal inflammation by inhibiting the activation of iRhom2/TACE signalling and attenuating ER stress. These results suggest that TFA has potential therapeutic value for the treatment of DN in humans.
Spatio‐temporal drought patterns of multiple drought indices based on precipitation and soil moisture: A case study in South Korea

This study aims to explore the spatio‐temporal characteristics of meteorological and agricultural droughts using the standardized precipitation index (SPI) and standardized soil moisture index (SSI), respectively, as well as their relationships over the past three decades (1986–2016) in South Korea. The SSI shows less frequent droughts and longer drought duration compared to the SPI, due to the gradual decrease in the autocorrelation functions of the SSI. The strongest cross‐correlations are observed at a 1‐month lag between the SPI and SSI for most stations. Thus, the SPI could be more appropriate for defining the onset of a drought, whereas the SSI appears to be more effective for describing drought persistence. Moreover, the transition from meteorological to agricultural droughts is significantly dependent on the season, indicating that the transition between them is highly correlated with antecedent moisture conditions. The copula‐based multivariate standardized drought index (MSDI) is introduced to explicitly postulate interdependence between the SPI and SSI in the context of a multivariate probability distribution. We employ a hierarchical agglomerative clustering approach along with a quantile regression model to better understand the spatio‐temporal pattern of the MSDI. More drought episodes under moderate to severe drought conditions are observed along the southern coast of South Korea. Additionally, persistent droughts with higher severity are observed in the northern part of South Korea, which may be attributed to a significant decreasing trend (or increasing drought risk).