Miracle-dz/UniFAR-FTUs huggingface dataset:
A Tunable 240–290 GHz Waveguide Enclosed 2-D Grid HBV Frequency Tripler

This paper presents a high-power 240-290 GHz waveguide enclosed two-dimensional (2-D) grid heterostructure barrier varactor (HBV) frequency multiplier. A 35 mW of output power is produced at 247 GHz with an input power of 900 mW. The operational bandwidth is tunable within a 50 GHz span by the use of an input tuner able to adjust the input matching of the 2-D grid HBV frequency multiplier. Tuning is achieved by moving a suspended dielectric slab in the input waveguide.
Characterization of Audiovisual Dramatic Attitudes

In this work we explore the capability of audiovisual parameters (such as voice frequency, rhythm, head motion or facial expressions) to discriminate among different dramatic attitudes. We extract the audiovisual parameters from an acted corpus of attitudes and structure them as frame, syllable, and sentence-level features. Using Linear Discriminant Analysis classifiers, we show that sentence-level features present a higher discriminating rate among the attitudes and are less dependent on the speaker than frame and sylable features. We also compare the classification results with the perceptual evaluation tests, showing that voice frequency is correlated to the perceptual results for all attitudes, while other features, such as head motion, contribute differently, depending both on the attitude and the speaker.
Graph‐theory‐based spectral feature selection for computer aided diagnosis of Parkinson's disease using T1‐weighted MRI

Parkinson's disease (PD) is a neurological disorder, which is diagnosed on the basis of clinical history and examination alone as there are no diagnostic tests available. However, the current diagnosis highly depends on the knowledge and experience of clinicians and hence subjective in nature. Thus, the focus of this study is to develop a computer‐aided diagnosis (CAD) method using T1‐weighted magnetic resonance imaging (MRI) to differentiate PD from controls.
Performance Analysis of Color Channel for DCT Based Image Watermarking Scheme

Due to improvements in imaging technologies and the ease of digital contents creation and manipulation, today there is a pressing need for the copyright protection of digital contents. It is also essential to have techniques for authentication of the content as well as the owner. This paper examines the suitability of color channel to be used for hiding a monochromatic watermark in a 24 bit colored BMP image. This paper uses the scheme which is based on comparison of middle band DCT coefficients exchange scheme [13]-[14]. This paper also proposes a way to improve the robustness against JPEG attack. Experimental results show that proposed scheme is very robust against JPEG compression along various kinds of image processing attacks.
Getting "Customer Lock On" Through Innovation in Services

AbstractThe following sections are included:IntroductionWorking on Twin Innovation TracksStep 1: Defining the Market SpaceDriving the Customer Lock-On LoopDefining the Opportunities to Add ValueCreating Win-Win for AllLeveraging from Existing Infrastructure and SkillsManaging Customer ContactBuilding an Extended Delivery NetworkTechnology as the EnablerDelivering Performance Managed DeliveryConcluding Remarks
Antibody response that protects against disseminated candidiasis

We previously showed that surface mannans of Candida albicans function as adhesins during yeast cell attachment to mouse splenic marginal zone macrophages. The mannan adhesin fraction was encapsulated into liposomes and used to vaccinate mice over a 5- to 6-week period. Circulating agglutinins specific for the fraction correlated with increased resistance to disseminated candidiasis. Antiserum from vaccinated animals protected naive BALB/cByJ mice against C. albicans serotype A and B strains and Candida tropicalis. Antiserum also protected SCID mice against disseminated disease. The serum protective ability was stable at 56 degrees C, but this ability was adsorbed by C. albicans cells. The antiserum was divided into three fractions after separation by high-performance liquid chromatography. One fraction contained all of the agglutinin activity and transferred resistance to naive mice. A second fraction also transferred resistance. Two monoclonal antibodies (MAbs) specific for candidal surface determinants were obtained. MAb B6.1 is specific for a mannan epitope in the adhesin fraction, and MAb B6 is specific for a different epitope in the fraction. Both MAbs are immunoglobulin M, and both strongly agglutinate candidal cells, but only MAb B6.1 protected both normal and SCID mice against disseminated candidiasis. In one experiment, 10 normal mice were given MAb B6.1 and challenged with yeast cells. Six mice survived the 67-day observation period; 4 of the survivors were cured as evidenced by the lack of CFU in the kidney and spleen. Our studies show that antibodies against certain cell surface antigens of C. albicans help the host resist disseminated candidiasis.
A new prediction method of alpha-stable processes for self-similar traffic

Because the self-similar processes have an infinite variance, the prediction method cannot be derived from the covariance. However, in the alpha-stable processes the covariation can be used to substitute the role of the covariance. Based on the theory of alpha-stable processes, a simple unbiased linear prediction method is developed for self-similar network traffic. The prediction method can be derived from the property of the covariation, and the prediction coefficients are solved from the cross-covariation matrix. The covariation orthogonality criterion ensures that the procedure of the prediction method is efficient and simple. The simulation experiments show that the new prediction method is able to predict the changes of the self-similar network traffic, especially in forecasting the bursty changes. As a result, this method can be used for network design so as to avoid network congestion.
A method to make a three-dimensional model of an individual face from a front view of a facial image only

The paper proposes a method to construct a three-dimensional model of an individual face automatically from a front view of a facial image only. The method is realized by estimating unevenness of facial features from isodensity lines on a front view of a facial image and by modifying a wire frame model of a generic face based on the estimated data of facial unevenness.
It Looked Like Spilt Milk

Thank you for downloading it looked like spilt milk. As you may know, people have search numerous times for their chosen novels like this it looked like spilt milk, but end up in malicious downloads. Rather than reading a good book with a cup of coffee in the afternoon, instead they cope with some malicious bugs inside their computer. it looked like spilt milk is available in our book collection an online access to it is set as public so you can download it instantly. Our digital library spans in multiple countries, allowing you to get the most less latency time to download any of our books like this one. Kindly say, the it looked like spilt milk is universally compatible with any devices to read.
A Software for Designing Oligonucleotides for PCR-Based Long DNA Synthesis

Herein we present a computer program to design oligonucleotide sets for gene assembly by both ligase chain reaction (LCR) and polymerase chain reaction (PCR). The program divides the long input DNA sequence based on the input number of oligonucleotides, and dynamically optimizes the length of oligonucleotides to achieve homologous melting temperatures. The output reports the melting temperatures, oligonucleotide sequences, and potential formation of secondary structures. The software has been successfully used in the design and synthesis of green fluorescent protein fragment (GFPuv) (760 bp), human protein kinase B-2 (PKB2) (1446 bp) and the promoter of human calcium-binding protein A4 (S100A4) (752 bp).
State and diagnostic value of plasma tissue factor in early‐hospitalised patients with chest pain

To study the state and diagnostic value of plasma tissue factor (TF) in patients with acute coronary syndromes (ACS), we quantitatively compared plasma TF antigen and TF activity in 90 early‐hospitalised patients with chest pain. Using high‐affinity antibodies, a sensitive assay for TF antigen was developed with a detection limit of 40 fmol/l. One of the antibodies was used to capture TF from plasma and, after elution and dialysis‐free reconstitution in phospholipid‐glucoside micelles, absolute amounts of TF activity could be measured with a detection limit of 80 fmol/l. All TF in plasma was found to be exposed, and a value of 2·5(1·1–14·8) pmol/l (median with range) was found for TF antigen. Most of this TF antigen (70–80%) circulated in a (potentially) functional state. Left in its in vivo state, however, TF captured from plasma was totally inactive, probably because of the lack of a procoagulant matrix. Compared with controls with non‐cardiac chest pain, TF activity was unchanged and TF antigen about 25% elevated in ACS patients. Combined with the markers prothrombin fragment F1+2 and fatty acid‐binding protein, TF did not improve the early diagnosis of ACS.
Improving Kernel-based protein-protein interaction extraction by unsupervised word representation

As an important branch of biomedical information extraction, Protein-Protein Interaction extraction (PPIe) from biomedical literatures has been widely researched, and machine learning methods have achieved great success for this task. However, the word feature generally adopted in the existing methods suffers badly from vocabulary gap and data sparseness, weakening the classification performance. In this paper, the unsupervised word representation approach is introduced to address these problems. Three word representation methods are adopted to improve the performance of PPIe: distributed representation, vector clustering and Brown clusters representation. Experimental results show that our method outperforms the state-of-the-art methods on five publicly available corpora.
Fabric Sol–gel Phase Sorptive Extraction Technique: A Review

Since the introduction in 2014 of fabric phase sorptive extraction (FPSE) as a sample preparation technique, it has attracted the attention of many scientists working in the field of separation science. This novel sorbent extraction technique has successfully utilized the benefits of sol–gel derived hybrid sorbents and a plethora of fabric substrates, resulting in a highly efficient, sensitive and green sample pretreatment methodology. The proposed procedure is an easy and efficient pathway to extract target analytes from different matrices providing inherent advantages such as high sample loading capacity and short pretreatment time. The present review mainly focuses on the background and sol–gel chemistry for the preparation of new fabric sorbents as well as on the applications of FPSE for extracting target analytes, from the time that it was first introduced. New modes of FPSE including stir FPSE, stir-bar FPSE, dynamic FPSE, and automated on-line FPSE are also highlighted and commented upon in detail. FPSE has been effectively applied for the determination of various organic and inorganic analytes in different types of environmental and biological samples in high throughput analytical, environmental, and toxicological laboratories.
Molecular dynamics study of the differences in the human defensin behavior near a modelled water/membrane interface

Human defensins HNP-1, HNP-2 and HNP-3 behavior is studied in a membrane interface model H2O/CCl4 by molecular dynamics simulation. The distinct HNP-3 behavior, when compared to HNP 1 and 2, can be associated to the fact that HNP-3 is the least potent of the three defensins, since its apolar residues, which could attack the cellular membranes of the pathogenic organisms, are shielded in the inner region of the peptide. Three mechanisms were proposed to explain the HNP action on cellular membranes. These mechanisms are unable to enlighten the membrane hydrophobic part role for preserving the quaternary structure of the peptide when it is interacting with the inner part of the membrane. They suggest that the damaging is mainly caused by the interactions between the localized charges of the peptides with charges on the membrane surface. These models do not clearly explain what the hydrophobic region role is in the stabilization of the quaternary HNP structure, when it is interacting with a membrane. The understanding of how the HNP dimers structure is conserved at the first stages of the insertion into the membrane is fundamental to explain the different activities of the peptides. This work aims at contributing for the understanding of the mechanism of the defensins antimicrobial action.
Supply-demand gap between small exporting creative firms and professional service providers

Creative SMEs are heavily focusing on the creating process designing new products and services. Consequently, their managers tend to loose contact with crucial management issues. Especially their knowledge of the financial aspects of their business can be so limited that they fail to connect with the financial viability of their business, which can lead to serious business problems. This paper draws on a number of studies that examine the role of outsiders -contracted professional service providers- in relation to business success of SMEs. In the light of the potential growth of Flemish creative SMEs on international markets the question can be raised as to what extent outsiders, and more specifically financial service providers like accountants and banks, contribute to the export success of these firms. In this paper therefore the role played by accountants and banks was explored to solve export-related questions by small furniture designers in Flanders, Belgium. Export can be considered as the most successful growth and therefore raises interesting management issues for creative SMEs. Little is known about the content and intensity of services of accountants and bank employees in relation to export-related questions of owner-managers of small creative firms. In order to examine the fit between supply and demand the focus is on outsider contribution during six phases of export.
Multilevel Design Optimization of a FSPMM Drive System by Using Sequential Subspace Optimization Method

In our previous research, flux-switching permanent magnet machine (FSPMM) was investigated for the application in hybrid electric vehicles. To obtain the best performance of the whole drive system, a new multilevel design optimization method is presented for this kind of machine and a field oriented control system. The proposed multilevel optimization method is based on sequential subspace optimization method. In the implementation, three levels are employed to obtain the optimal design scheme at the system level. Meanwhile, sequential optimization method is employed to reduce the computation cost of finite element analysis on the motor level. Finally, from the design analysis, it can be found that the proposed method can provide design scheme with better performance, while the needed computation cost is reduced greatly for this FSPMM drive system.
Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers

Significance In previous work, we used genome-wide screening to uncover a counterintuitive mechanism by which cells can acquire resistance to inhibitors of the proteasome’s catalytic core through experimentally induced imbalances in the composition of its regulatory particle. However, in many cases, mechanisms uncovered in vitro for acquired resistance often do not translate to the context of actual clinical cancers. Here, we show that this mechanism is actually deployed spontaneously and naturally in diverse human cancer lines and is associated not only with increased resistance to proteasome inhibitors both in vitro and in the clinic but also is symptomatic of a much more broadly altered state with a unique gene signature and drug targetable vulnerabilities. The use of proteasome inhibitors to target cancer’s dependence on altered protein homeostasis has been greatly limited by intrinsic and acquired resistance. Analyzing data from thousands of cancer lines and tumors, we find that those with suppressed expression of one or more 19S proteasome subunits show intrinsic proteasome inhibitor resistance. Moreover, such proteasome subunit suppression is associated with poor outcome in myeloma patients, where proteasome inhibitors are a mainstay of treatment. Beyond conferring resistance to proteasome inhibitors, proteasome subunit suppression also serves as a sentinel of a more global remodeling of the transcriptome. This remodeling produces a distinct gene signature and new vulnerabilities to the proapoptotic drug, ABT-263. This frequent, naturally arising imbalance in 19S regulatory complex composition is achieved through a variety of mechanisms, including DNA methylation, and marks the emergence of a heritably altered and therapeutically relevant state in diverse cancers.
The rise and decline of the UK's provincial stock markets, 1869-1929

The London Stock Exchange was the largest capital market in the world at the beginning of the twentieth century, but Britain also had numerous other stock markets based in provincial cities and towns. This paper provides the first in-depth quantitative assessment of these markets. We find that they were an important source of financing for regional companies up until circa 1900 and our evidence suggests that their post-1900 decline was largely due to the changing characteristics of publicly-listed firms. We also find that the provincial and London markets became increasingly integrated over time.
Building Different Levels of Legitimacy in Internationalisation: Subsidiary – Civil Society Nexus in Institutional Void

Drawing on empirical examination of six European MNE-subsidiaries and using a multiple-case method & process analysis, this paper investigates the nexus between subsidiaries & civil society actors in institutional void that affect legitimacy development. Study finds four different levels (i.e. degree) of legitimacyacceptance, image, endorsement, and synergy (acceptance + efficiency) that subsidiaries earn, develop, or co-develop in collaboration with CS actors in internationalization. Our study brings a new insight on legitimacy theory in international management in a way that isomorphism perspective of legitimacy cannot explain the complexity of subsidiary legitimization in institutional void. This is because subsidiaries not only earn acceptance by complying to institutional context, they also create and co-create image, endorsement and synergy by strategic initiatives. We thus combine institutional isomorphism and institutional innovation perspective in legitimization and conclude that subsidiaries strategic endeavours generate various levels of legitimacy as an output; not just acceptance level only. It is although difficult to separate legitimacy and efficiency as an intermingled strategic outcome because subsidiaries fill up institutional void by institutional innovation and create operational efficiency as well as legitimacy in market and society. We therefore conceptualize the development of different levels of legitimacy using a ‘spiral metaphor’ and combine isomorphism perspective with institutional innovation and business model-fit in order to illustrate how they influence legitimacy and efficiency development in institutional void context. C: Competitive Session 1.4. 8: Knowledge in the MNE Time: Saturday, 03/Dec/2016: 3:30pm 5:00pm
A study of market efficiency in Asian emerging markets-evidence of the January Effect and Momentum Effect

The purpose of our study is trying to investigate the market efficiency in Asian emerging markets. The Asian emerging stock markets developed dramatically in the last decade and more and more individual investors joined the markets. It is rational to expect the market price behavior could be inconsistent with developed markets where the institutional investors are the majority. Two market anomalies of calendar effect and momentum effect are employed as the evidence to this study. It aims to provide useful information for potential Asian investors. Using T-test to examine the January Effect and using Moving Average price index (MA) technical analyze to investigate the Momentum effect. However we did not find market anomaly, namely January Effect. But there were indications of Momentum effect.
Effect of Particle Shape on the Mixing of Powders

Abstract— Mixtures were prepared containing 200 g of 600 μm lactose and 0.5 g of 3 μm calcium carbonate of different particle shapes using a Y cone mixer. Measurements were made of the time required to achieve the acceptable standard deviation of mixing σA and of the segregation that occurred on subsequently vibrating the mixtures. The time taken to achieve σA increased with the irregularity of the particles of both components and the mixtures containing irregular particles segregated less on vibration.
ANTIGENIC RELATIONSHIPS BETWEEN GROUPS B AND G STREPTOCOCCI

Trypsinized cell walls of Group B hemolytic streptococci are composed of a group-specific carbohydrate and mucopeptide. The carbohydrate extracted with hot formamide is composed of rhamnose, N-acetylglucosamine, and galactose. Quantitative precipitin inhibition studies have shown that L rhamose is the significant component of the antigenic determinant. The cross-reactivity between B and G carbohydrates is dependent upon the fact that Lrhamose is a determinant sugar in both antigens.
State and Disturbance Estimation Based on Internal Model Control Structure and Its Application to Sensorless Grasping Control

A new controller scheme based on the IMC design structure is proposed in this paper. Due to using an inverse system or an approximate inverse system for the IMC structure, the order of the controller leads the high order, meanwhile the high order controller is not practical in implementation. This paper is concerned with the problem of reducing a high order controller to a reduced order one. The disturbance estimation property of the closed loop system is also discussed. The proposed controller scheme is applied to a prototype robotic hand that can hold an object with suitable grasping force without force sensor. The effectiveness of the proposed controller scheme is confirmed by experiments.
Association of Aurora‐A (STK15) kinase polymorphisms with clinical outcome of esophageal cancer treated with preoperative chemoradiation

Aurora‐A/STK15 is a serine/threonine kinase critical for regulated chromosome segregation and cytokinesis. We investigated the association between 2 nonsynonymous single nucleotide polymorphisms in the coding region of STK15, T91A (Phe31Ile) and G169A (Val57Ile), and clinical outcome of esophageal cancer treated with preoperative chemoradiation.
Inhibition of granulocyte adherence by ethanol, prednisone, and aspirin, measured with an assay system.

Abstract A simple, rapid, in vitro assay was developed to study granulocyte adherence, an important component of the inflammatory reaction. Heparinized whole blood is filtered through nylon fiber packed in Pasteur pipettes, and the percentage of granulocytes adhering is calculated. Test variability from morning to evening, before and after meals, and on successive days is less than 10 per cent. In vitro exposure of whole blood to ethanol concentrations varying from 100 to 1000 mg per 100 ml caused a dose-dependent, significant inhibition of adherence (16–87 per cent, p<0.05), but incubation with sodium salicylate (5 to 50 mg per 100 ml) or hydrocortisone sodium succinate (500 to 3000 μg per 100 ml) had no effect. In all volunteers receiving 40 mg of prednisone or 1.2 g of aspirin, impaired adherence developed, suggesting that glucocorticoids and salicylates may affect adherence in vivo by inducing an inhibitor. The anti-inflammatory effect of salicylates, hydrocortisone and ethanol may be secondary to the.