Miracle-dz/UniFAR-FTUs huggingface dataset:
A Computational Model for Predicting Protein Interactions Based on Multidomain Collaboration

Recently, several domain-based computational models for predicting protein-protein interactions (PPIs) have been proposed. The conventional methods usually infer domain or domain combination (DC) interactions from already known interacting sets of proteins, and then predict PPIs using the information. However, the majority of these models often have limitations in providing detailed information on which domain pair (single domain interaction) or DC pair (multidomain interaction) will actually interact for the predicted protein interaction. Therefore, a more comprehensive and concrete computational model for the prediction of PPIs is needed. We developed a computational model to predict PPIs using the information of intraprotein domain cohesion and interprotein DC coupling interaction. A method of identifying the primary interacting DC pair was also incorporated into the model in order to infer actual participants in a predicted interaction. Our method made an apparent improvement in the PPI prediction accuracy, and the primary interacting DC pair identification was valid specifically in predicting multidomain protein interactions. In this paper, we demonstrate that 1) the intraprotein domain cohesion is meaningful in improving the accuracy of domain-based PPI prediction, 2) a prediction model incorporating the intradomain cohesion enables us to identify the primary interacting DC pair, and 3) a hybrid approach using the intra/interdomain interaction information can lead to a more accurate prediction.
Newton-type method in spectrum estimaion-based AOA estimation

For numerical optimization of the cost function of the maximum likelihood (ML) algorithm for angle-of-arrival (AOA) estimation, Newton-type method has been widely employed. In this paper, we apply the Newton-type method to the optimization of cost function for spectrum estimation-based AOA estimation algorithm of the conventional beamforming, the Capon beamfomring and the MUSIC algorithm. Explicit expressions of the first derivatives and the second derivatives of the cost functions are presented. The expressions are used for the Newton iteration to improve the accuracy of the initial estimates. The performance improvement in terms of estimation accuracy and computational burden is demonstrated using the Monte-Carlo simulations.
Fair media access for wireless LANs

This paper addresses load balancing algorithms for the wireless links to solve the fairness problem, where stations are not able to gain access equally to the shared wireless medium. The fairness problem occurs mostly because of the existence of hidden stations and the presumption of a non-fully connected wireless network topology. In this paper, p/sub ij/-persistent carrier sense multiple access based algorithms are proposed in which a fair wireless access for each user is accomplished using a pre-calculated link access probability. Link access probabilities are calculated at the source station in two ways using connection-based and time-based media access methods. Each active user broadcasts information on either the number of logical connections or the average contention time to the stations within the communication reach. Each station reserves a specific priority for its each link to gain access to the shared medium based on the exchanged information. The proposed algorithms are dynamic and sensitive to the changes in the network topology. They are applicable to all CSMA based media access control protocols to provide a degree of fairness.
Taurine blunts LPS‐induced increases in intracellular calcium and TNF‐α production by Kupffer cells

Activation of Kupffer cells by lipopolysaccharide (LPS) plays a pivotal role in the onset of pathophysiological events that occur during endotoxemia and intracellular calcium ([Ca2+]i) is involved in LPS‐stimulated cytokine production. Recently, it was shown that Kupffer cells contain a glycine‐gated chloride channel. Because taurine, a ubiquitous sulfur‐containing β‐amino acid, acts similarly to glycine in neurons by causing hyperpolarization, it was hypothesized that taurine would act via a similar mechanism, blunting the LPS‐induced increase in [Ca2+]i in Kupffer cells. To test this hypothesis, Kupffer cells were isolated from female Sprague‐Dawley rats and cultured for 24 h. LPS‐induced changes in [Ca2+]i were monitored fluorometrically in single cells, whereas levels of tumor necrosis factor α (TNF‐α) released by Kupffer cells after exposure to LPS were measured by enzyme‐linked immunosorbent assay. Taurine significantly blunted the LPS‐induced increase in [Ca2+]i in a dose‐dependent manner (IC50, 0.1 mM). This effect was reversed by strychnine (1 μM) and was prevented when chloride was removed from the extracellular media. Moreover, taurine increased 36Cl– uptake by Kupffer cells in a dose‐dependent manner (EC50, 0.2 mM). Furthermore, strychnine (1 μM) reversed the effect of taurine on 36Cl– uptake. These results indicate that taurine activates a glycine‐gated chloride channel in Kupffer cells causing chloride influx. In addition, LPS‐induced TNF‐α production was reduced by more than 40% by taurine, an effect that was also reversed by strychnine. In conclusion, taurine blocks the increase in [Ca2+]i due to LPS and significantly reduces TNF‐α production by mechanisms involving chloride influx into the Kupffer cell. J. Leukoc. Biol. 64: 615–621; 1998.
Motion planning for a two-link planar robot in a viscous environment

This paper is concerned with gait generation for the simplest underactuated multi-link robot. This robot is realized by a two-link planar system that locomotes in a viscous environment due to the existence of friction pads along its body. The proposed solution of the motion planning problem yields both a control gait for the inter-link angle as well as the location of the friction pad to produce a desired motion of the system.
A denotational semantics for the Starburst production rule language

Researchers often complain that the behavior of database production rules is difficult to reason about and understand, due in part to the lack of formal declarative semantics. It has even been claimed that database production rule languages inherently cannot be given declarative semantics, in contrast to, e.g., deductive database rule languages. In this short paper we dispute this claim by giving a denotational semantics for the Starburst database production rule language.
Preprocessing of Scenarios for Fast and Efficient Routing Reconfiguration in Fault-Tolerant NoCs

Newest processes of CMOS manufacturing allow integrating billions of transistors in a single chip. This huge integration enables to perform complex circuits, which require an energy efficient communication architecture with high scalability and parallelism degree, such as a Network-on-Chip (NoC). However, these technologies are very close to physical limitations implying the susceptibility increase of faults on manufacture and at runtime. Therefore, it is essential to provide a method for efficient fault recovery, enabling the NoC operation even in the presence of faults on routers or links, and still ensure deadlock-free routing even for irregular topologies. A preprocessing approach of the most probable fault scenarios enables to anticipate the computation of deadlock-free routings, reducing the time necessary to interrupt the system operation in a fault event. This work describes a preprocessing technique of fault scenarios based on forecasting fault tendency, which employs a fault threshold circuit and a high-level software that identifies the most relevant fault scenarios. We propose methods for dissimilarity analysis of scenarios based on measurements of cross-correlation of link fault matrices. At runtime, the preprocessing technique employs analytic metrics of average distance routing and links load for fast search of sound fault scenarios. Finally, we use RTL simulation with synthetic traffic to prove the quality of our approach.
If women counted : a new feminist economics

This is a revolutionary and powerfully argued feminist analysis of modern economics, revealing how woman's housework, caring of the young, sick and the old is automatically excluded from value in economic theory. An example of this pervasive and powerful process is the United Nation System of National Accounts which is used for wars and determining balance of payments and loan requirements. The author has also written "Women, Politics and Power" and is a formidable force in the politics of New Zealand, serving three terms in Parliament and helping bring down a Prime Minister. She holds a doctorate in political economy and was a visiting Fellow at Harvard's Kennedy School of Government.
Multi-domain product modelling: from requirements to cad and simulation tools.

Today, in a very competitive industrial context, different companies have difficulties to respect delays in design and manufacturing of multi-domain product. These difficulties are most of time due to the non respect of requirements defined at the beginning of the project development, during the Function Performance Specifications phase. Furthermore, an important problem during multi-domain products design and development process is the communication between experts of different domains. To answer to this problem, the authors propose in this paper to describe and analyze this problematic through a meta-model. They focus only on mecatronic product. From the proposed meta-model analysis, they develop two possible links between both mechanical and electronic domains in a model: (1) between models and (2) between analysis tools of different domains. The application of this model to a concrete example shows that we can link all the main common data of a product design and development to the modeling and simulation tools of different domains.
Private Schools and the Demand and Supply of Public School Quality in Metropolitan Areas

The role of private schools in the housing market and in the supply and demand for public schooling is investigated. The following are new to demand for public schooling studies: accounting for spatial autocorrelation in the hedonic house price estimation and the supply and demand, a theoretical model of education supply, an empirical estimation of supply, and addressing hedonic sample selection bias. Public school quality supply seems responsive to private school competition but not to competition from other public schools. The percentage of school-aged children attending private schools seems positively associated with house values, holding public schooling outcomes constant. JEL Classification codes: H41, R21, R22
The Challenges of the Civil Service Reform in Ethiopia: Initial Observations

Ethiopia, as part of its general political and economic restructuring program, is currently reforming its civil service. Using qualitative data, the study analyses the contents and processes of the civil service reform program. It emerges from the study that the reform measures have deficiencies in tackling the major problems confronting the Ethiopian civil service. This has been due, inter alia, to faulty diagnosis of the problems underlying the weaknesses of the civil service. It is also found that the reform measures lack the necessary preconditions to be adequately put into practice. The paper concludes by arguing that the reform measures must be contextualised and executed incrementally by identifying priority areas, while taking into consideration capacity to implement the measures proposed. Eastern Africa Social Science Research Review (EASSRR) Vol. XVII No. 1 January 2001, pp. 79-102
DRAFT: Conspicuous Conservation: The Prius Effect and WTP for Environmental Bona Fides∗

Veblen explained in 1899 that “in order to gain and hold the esteem of man it is not sufficient merely to possess wealth or power. The wealth or power must be put in evidence, for esteem is awarded only on evidence. ” Since then, a considerable economics literature has explored the concept of conspicuous consumption and its implications in various settings, with particular focus on purchases that signal prestige, luxury and exclusivity.1 While consumption of luxurious automobiles, jewelry and apparel surely still afford desired social status in the 21st Century, evolving social norms suggest esteem can be attained through the demonstration of certain kinds of austerity–specifically austerity that minimizes the environmental impact of consumption. In fact, amid heightened concern about environmental damage and global climate change, costly private contributions to environmental protection increasingly confer status once afforded only through ostentatious displays of wastefulness. Consumers may, therefore, undertake costly actions in order to signal their type as environmentally friendly or “green. ” The status conferred upon demonstration of environmental friendliness is sufficiently prized that homeowners are known to install solar panels on the shaded sides of houses so that their costly investments are visible from the street. We call this behavior “conspicuous conservation. ” Home solar panel installation and car ownership decisions are two of the most visible consumption decisions households make. Since the U.S. introduction of
Regularized training of compositional distributional semantic models

The compositional distributional semantic models (cDSMs) aim to use numerical vectors to represent the meaning of complex language expressions. cDSMs are usually trained using single training target, either from the basic DSM or a pseudo gold standard. In this paper, a new regularized training approach that integrates multiple training targets is proposed to improve semantic composition models. The experiment results show that the proposed training algorithm can effectively enhance compositional distributional semantic models.
Exploring Information and Communication Theory in Graphic Design Education with Activity Theory

1. ABSTRACT In the context of a university in a developing country, large class size and inadequate studio space have become the bane of graphic design educators. Students go through the process of ideation with limited lecturer-student interaction. The problem has been compounded by the introduction of information and communication technology (ICT), which should be used as an advantage rather than a menace, since educators are not clear with the right pedagogy for ideation. This paper discusses the application of activity theory as a lens, in analysing the process of ideation as a way of looking at distortions in the current pedagogy. It concludes with the conviction that ICT has radically changed students learning practice. Educators need to find a way of tackling this, especially when large classes seem to be emerging.
The teleological origins of mentalistic action explanations: A developmental hypothesis

In this paper we shall argue that mentalistic action explanations, which form an essential component of a mature theory of mind, are conceptually and developmentally derived from an earlier and purely teleological interpretational system present in infancy. First we summarize our evidence demonstrating teleological action explanations in one-year-olds. Then we shall briefly contrast the structure of teleological vs. causal mentalistic action explanations and outline four logical possibilities concerning the nature of the developmental relationship between them. We shall argue for the view that causal mentalistic action explanations are constructed as useful theoretical extensions of the earlier, purely teleological, nonmentalistic interpretational stance.
Ant-based Reputation Evidence Distribution in P2P Networks

How to manage trust is regarded as a main problem of security issues in P2P overlay networks. Reputation-based trust management is regarded as a promising way to solve the problem. However, in P2P systems, obtaining reputation evidence for building trust relationships is not an easy job. We tackle this problem by employing a scheme for the distribution of reputation evidence, which is based on the swarm intelligence paradigm. Our simulations show that it performs very well in P2P environment. We hope that this method will help move the reputation based trust management closer to fulfilling its promise in P2P networks
Student Awareness Model based on student affective response and generic profiles

This paper outlines strategies intended to develop a comprehensive Student Awareness Model. In order to develop the model, a combination of two approaches was used to extract students' profile information. The first approach was an automatic approach, in which more emphasis was placed on students' affective responses. In order to obtain this information, a facial expression recognition application was developed to record positive or negative affective responses, as well as an application that utilized Microsoft Kinect Sensors to record changes in students' sitting positions during real-time learning. Alongside this approach, supporting information obtainable through data utilization of university's information system database was examined, such as the student's generic profile data. With such comprehensive data, developing a Student Awareness Model, the main driver in developing a Personalized Teaching Strategy, will be easier to achieve.
Stochastic behaviour in the edge region of the SINP tokamak

Stochasticity is one of the most extensively researched topics in laboratory and space plasmas since it has been successful in explaining the various anomalous processes like transport, particle heating, particle loss etc. Since there is a growing need for better understanding of this nonlinear process, it has led to the development of new and more advanced data analysis techniques. In this paper we present an analysis of the floating potential fluctuations which show the existence of a stochastic multifractal process along with low dimensional chaos. This has been shown primarily by wavelet analysis, and cross checked using other nonlinear techniques.
Prosody in L 2 Acquisition

Prosodic structure, as it couples with information structure, is an integral component of the felicity of an utterance. A string of coherently arranged elements is uniquely flagged for discourse by its prosody (comprised of intonation, stress, and rhythm), separating peaks from valleys in the discourse topography. The placement of stress does carry meaning in that it indicates the scope of the focused information – an all-important feature of information structure. The current study makes a cross-linguistic comparison of the nature of the prosody-focus relationship and how it manifests itself. The research question posed here is whether or not English and Spanish differ with regards to prosody for certain focus constructions, and if so, where evidence of this difference can be found. Once it has been established how things work in each language, we move on to a hypothesis and a number of predictions of what is expected to happen in a situation of adult second language acquisition. The current study is of particular import to the area of acquisition due to the somewhat tacit nature of the acquisition process: there are no prosodic structure paradigms or prosody rules for learners to memorize, as are available for irregular verb tenses or plural formations, etc. Nonetheless, languages (rather, their speakers) capitalize on the existence of this communicative feature. The research presented here is advanced in the same vein: observing the production behavior of speakers who wield more than one system provides us with an opportunity to understand how language-specific constraints are manifested. In order to answer the posed research question, it is first necessary to spell out the differences between English and Spanish, as detailed in section 1. The hypothesis and predictions of what is expected to happen in an acquisition situation are given in section 2. Section 3 details the method and experimental approach used to collect data; section 4 presents the results of the data analysis. The final section, section 5, is a discussion and conclusion of the research presented here.
Detection of antibodies to Fasciola and Anisakis in Japanese patients with intravascular lymphomatosis.

Recently, we reported five Japanese patients with large B-cell lymphoma associated with hemophagocytic syndrome, ie, malignant histiocytosis-like B-cell lymphoma, and suggested that they might be regarded as an aggressive variant of intravascular lymphomatosis (IVL) based on the localization of tumor cells within the sinus and vessels of the involved organs. 1 Phenotypically, these lymphomas were CD5 2, CD102, CD191, CD201, and HLA-DR1, with monoclonal rearrangement of the Ig heavy chain gene in two cases. They were also clinically characterized by onset in middle age or old age, fever, anemia, thrombocytopenia, hepatosplenomegaly, initial involvement of the bone marrow, hemophagocytosis, and a rapidly aggressive clinical course. Lymphadenopathy, skin lesions, neurological abnormalities, or peripheral blood lymphocytosis were rarely observed during the entire clinical course. Laboratory examinations showed elevated levels of D-D dimer, lactate dehydrogenase, C-reactive protein, interleukin-6 (IL-6), and the soluble IL-2 receptor isoforms, but not IL-1 b, IL-2, or tumor necrosis factor-a, with serologic evidence of abnormal immune function such as circulating antinuclear antibody. Interestingly, more than 30 cases of malignant histiocytosis-like B-cell lymphoma or IVL with hemophagocytic syndrome have been reported exclusively in Asian patients, with only a few cases in Western patients, and their clinical features appeared to differ considerably from those of typical IVL in Western countries. We therefore proposed that this group should be called an Asian variant of IVL (AIVL). In our series, antibodies against human T-cell lymphotropic virus type-I were negative, and Epstein-Barr virus was not detected by in situ hybridization. Notably, in one of the autopsied cases (case no. 5 in our previous report), circumscribed egg granulomas of Schistosoma japonicumwere observed to be distributed among the lymphoma cells in the liver (Fig 1). This unusual finding prompted us to perform a seroimmunological survey for helminthous infections associated with AIVL, because some parasites, as well as viruses, most likely play an important role in the etiology of several endemic lymphoproliferative diseases. 2-4
You Mate, I Mate: Macaque Females Synchronize Sex not Cycles

Extended female sexuality in species living in multimale-multifemale groups appears to enhance benefits from multiple males. Mating with many males, however, requires a low female monopolizability, which is affected by the spatiotemporal distribution of receptive females. Ovarian cycle synchrony potentially promotes overlapping receptivity if fertile and receptive periods are tightly linked. In primates, however, mating is often decoupled from hormonal control, hence reducing the need for synchronizing ovarian events. Here, we test the alternative hypothesis that females behaviorally coordinate their receptivity while simultaneously investigating ovarian cycle synchrony in wild, seasonal Assamese macaques (Macaca assamensis), a promiscuous species with extremely extended female sexuality. Using fecal hormone analysis to assess ovarian activity we show that fertile phases are randomly distributed, and that dyadic spatial proximity does not affect their distribution. We present evidence for mating synchrony, i.e., the occurrence of the females' receptivity was significantly associated with the proportion of other females mating on a given day. Our results suggest social facilitation of mating synchrony, which explains (i) the high number of simultaneously receptive females, and (ii) the low male mating skew in this species. Active mating synchronization may serve to enhance the benefits of extended female sexuality, and may proximately explain its patterning and maintenance.