Miracle-dz/UniFAR-FTUs huggingface dataset:
Diethyl (E)-2,3-bis[(E)-(2-methyl-2-phenylhydrazin-1-ylidene)methyl]but-2-enedioate

The complete molecule of the title compound, C24H28N4O4, is generated by crystallographic inversion symmetry. The ethyl side chain is disordered over two sets of sites in a 0.57 (4):0.43 (4) ratio. The dihedral angles between the methylidene group and the phenyl ring and ester side chain (major conformation) are 7.61 (8) and 86.95 (8)°, respectively. In the crystal, molecules are linked via C—H⋯O hydrogen bonds, forming corrugated sheets lying parallel to (010).
Lying behaviour and IgG-levels of newborn calves after feeding colostrum via tube and nipple bottle feeding

Oesophageal tube feeding colostrum is used to ensure sufficient colostrum intake in newborn calves but the impact of tube feeding on animal behaviour is unclear. Therefore the objective of this study was to compare lying behaviour of tube-fed or bottle-fed dairy calves. Calves (n = 37) in 3 groups were offered 3·5 l colostrum 2 h after birth. Calves of the bottle group were fed with a nipple bottle. Calves of the placebo tubing group were tubed for 4 min but no colostrum was given and they were then fed with a nipple bottle. Calves of the tubing group received 3·5 l colostrum via tube feeding. Consumed amount of bottle and placebo tubing calves was recorded. If they refused some of the offered 3·5 l the rest was offered in a second feeding 2 h later. Lying behaviour was measured by data loggers fitted to right hind leg for 3 d. Blood samples were taken 24 h after birth for determination of IgG concentration. The voluntary colostrum intake differed significantly between bottle-fed and placebo tubed calves at first feeding. Considering both colostrum feedings, bottle-fed calves consumed 3·44 ± 0·14 l and placebo tubed calves consumed 3·20 ± 0·38 l colostrum. ImmunoglobulinG intake (255·6 ± 77·5 g IgG), serum IgG concentration 24 h after birth (22·8 ± 6·7 g/l) and total serum protein concentration (6·1 ± 0·6 g/dl) did not differ between groups. None of the calves had a failure of passive transfer. There was no effect of tubing on lying behaviour.
Determinants of pig farmers’ participation in an animal welfare program

Despite frequent criticism, only few animal welfare attempts have been made towards an increase in terms of a dominant animal solution. Since farmers’ willingnesstoengage in animal welfare attempts is crucial, this study investigates farmers’ willingness-to-participate in an animal welfare program, which comprises a mandatory set of animal welfare measures. Data from a survey among members of a Northern German pig farmer cooperative has been used. With Theory of Planned Behavior as a theoretical framework a particularly analyze how single animal welfare measures influence farmers’ willingnesstoparticipate has been run. Three groups of farmers are identified, namely, the “refusing” the “undecided” and the “acquiescing”. The multinomial logit regression shows that while the refusing group is significantly more negative than the undecided about at least three of the eight required measures, the acquiescing group does not significantly differ from the undecided with respect to evaluation of measures. Rather, they exhibit a tendency to be more proactive, while the undecided feel more like being victims of societal pressure. The article concludes that it will be crucial to work on farmers’ beliefs, with respect to feasibility as well as with respect to perceived locus of control.
The Peritraumatic Distress Inventory: a proposed measure of PTSD criterion A2.

OBJECTIVE Meeting criterion A2 for the diagnosis of posttraumatic stress disorder (PTSD) in DSM-IV requires that an individual have high levels of distress during or after the traumatic event. Because of the paucity of valid and reliable instruments for assessing such responses, the authors developed a 13-item self-report measure, the Peritraumatic Distress Inventory, to obtain a quantitative measure of the level of distress experienced during and immediately after a traumatic event. METHOD The cross-sectional study group comprised 702 police officers and 301 matched nonpolice comparison subjects varying in ethnicity and gender who were exposed to a wide range of critical incidents. RESULTS The Peritraumatic Distress Inventory was found to be internally consistent, with good test-retest reliability and good convergent and divergent validity. Even after controlling for peritraumatic dissociation and for general psychopathology, the authors found that Peritraumatic Distress Inventory scores correlated with two measures of posttraumatic stress symptoms. CONCLUSIONS The Peritraumatic Distress Inventory holds promise as a measure of PTSD criterion A2. Future studies should prospectively examine the ability of the Peritraumatic Distress Inventory to predict PTSD and its associated biological and cognitive correlates in other trauma-exposed groups.
A reassessment of the Anglo-Saxon artefacts from Scotland: material interactions and identities in early medieval northern Britain

This thesis identifies and interprets the 5th to 9th-century Anglo-Saxon artefacts found within modern Scotland. It uses them to consider material expressions of ethnogenesis and to examine political, economic and ecclesiastical relations within early medieval northern Britain. In total, 221 objects are catalogued and discussed. The earliest finds suggest contact with the changing late/post-Roman frontier, while among the latest objects is a hacked finger ring deposited in a Viking-age hoard. The corpus includes several pieces of early 6th-century Style I metalwork, a cluster of 7th-century elite gold and garnet fittings, a large number of glass beads, a group of loom weights, and a substantial body of 8th/9th-century strap-ends and pins. Many are stray finds, though material was identified among excavated assemblages from monastic, chapel, settlement, hillfort and crannog sites, and from the chance discovery of several hoards and burials. In an attempt to move beyond a culture-history paradigm that has been deeply embedded in past work on these artefacts, this thesis employs the theories of hybridisation and entanglement, emphasising agency in the selection and reimagination of material culture in processes of identity creation. It identifies evidence for the promulgation of an elite Anglo-Saxon identity in 7th-century Lothian and argues that the region was being presented as a royal heartland. Bordering areas appear to have rejected Anglo-Saxon material culture outright, while regions further away, particularly Galloway and Argyll, were receptive to using and hybridising it. It is suggested that these differences were governed by the desire to show difference from immediate neighbours (for instance between polities within the Solway region) or create new identities (for instance incorporating former kindred-groups in Argyll). Different patterns were apparent in the 8th/9th-century finds: south-east and south-west Scotland appear to have had similar access to late Anglo-Saxon material, including a handful of high-status objects manufactured within Northumbria, while other parts of Scotland produced relatively few finds beyond imported vessel glass and a scatter of metal finds along the coast. While this might suggest a similar cultural context across southern Scotland and a contrast to that north of the Forth–Clyde, differences in deposition, particularly in the presence of hoards in the south-west, show the material was clearly being used and conceived differently. Above all else, this thesis demonstrates that no work on early medieval Northumbria should ignore material found north of the modern national border.
Understanding the influence of development interventions on women beneficiaries' perceptions of empowerment: A case study in South Sulawesi, Indonesia

This thesis argues that international development interventions influence the way women perceive empowerment. It does so by looking at aid relationships and the relevance of development interventions. It involves a case study of Oxfam’s Restoring Coastal Livelihoods Project (2010-2015) in South Sulawesi, Indonesia. Efforts to empower women have been channeled through various approaches. However, little has been said about the practice of aid relations within projects and how aid relations work through the ‘aid chain’ and influence women’s perceptions of empowerment. Also, there has not been much said about how, in the intersectionality of aid relationships, women make ‘empowerment’ their own, appropriate it, transform it, adapt it to their stories and needs through their active engagement in projects. The qualitative research which involved a five-month period of ethnographic research found that women beneficiaries perceived empowerment mostly based on their experiences in the project. However, the degree of empowerment is relative to the types of women’s engagement, the nature of activities, and their general understanding of gender relations. The project has brought economic-driven gender awareness by facilitating women’s practical and strategic needs through economic groups. It has also brought empowerment consequences which went beyond the economic dimension. The research highlights the importance of personal, relational, and multidimensional aspects of empowerment in women’s perceptions of empowerment. Efforts to empower women seem to still rely on external intervention to facilitate the process and to deal with existing dynamics of power relations. The findings reassert that women’s empowerment requires enabling internal and external environments to promote women’s awareness of, and capacity for, empowerment. Finally, the thesis underlines that empowerment depends highly on women’s personal experiences, awareness, agency, resources, choice, willingness, and commitment. This research contributes to our understanding of women, aid, and development as it highlights the multidimensional and multi-layered aspects of aid relations and women’s empowerment.
Multi-Label Feature Selection using Correlation Information

High-dimensional multi-labeled data contain instances, where each instance is associated with a set of class labels and has a large number of noisy and irrelevant features. Feature selection has been shown to have great benefits in improving the classification performance in machine learning. In multi-label learning, to select the discriminative features among multiple labels, several challenges should be considered: interdependent labels, different instances may share different label correlations, correlated features, and missing and flawed labels. This work is part of a project at The Children's Hospital at Westmead (TB-CHW), Australia to explore the genomics of childhood leukaemia. In this paper, we propose a CMFS (Correlated- and Multi-label Feature Selection method), based on non-negative matrix factorization (NMF) for simultaneously performing feature selection and addressing the aforementioned challenges. Significantly, a major advantage of our research is to exploit the correlation information contained in features, labels and instances to select the relevant features among multiple labels. Furthermore, l2,1 -norm regularization is incorporated in the objective function to undertake feature selection by imposing sparsity on the feature matrix rows. We employ CMFS to decompose the data and multi-label matrices into a low-dimensional space. To solve the objective function, an efficient iterative optimization algorithm is proposed with guaranteed convergence. Finally, extensive experiments are conducted on high-dimensional multi-labeled datasets. The experimental results demonstrate that our method significantly outperforms state-of-the-art multi-label feature selection methods.
From session causality to causal consistency

We discuss relationships between client-centric consistency models (known as session guarantees), and data-centric consistency models. The first group includes: read-your-writes guarantee, monotonic-writes guarantee, monotonic-reads guarantee and writes-follow-reads guarantee. The other group includes: atomic consistency, sequential consistency, causal consistency, processor consistency, PRAM consistency, weak consistency, release consistency, scope consistency and entry consistency. We use a consistent notation to present formal definitions of both kinds of consistency models in the context of replicated shared objects. Next, we prove a relationship between causal consistency model and client-centric consistency models. Apparently, causal consistency is similar to writes-follow-reads guarantee. We show that in fact causal consistency requires all common session guarantees, i.e. read-your-writes, monotonic-writes, monotonic-reads and writes-follow-reads to be preserved.
Superior Mesenteric Artery Syndrome in Children: A 20-Year Experience

Objectives: Superior mesenteric artery syndrome (SMAS), Wilkie syndrome or cast syndrome is a rare condition that usually presents with symptoms of mid to upper gastrointestinal obstruction due to the compression of the duodenum between the abdominal aorta, posteriorly, and the superior mesenteric artery, anteriorly. The aim of this study was to analyze the clinical characteristics, means of diagnosis and management of SMAS in a pediatric population. Methods: Retrospective chart review of all patients at the Children's Hospital of Wisconsin with SMAS from 1985 to 2005. Results: Twenty-two cases of SMAS where diagnosed at Children's Hospital of Wisconsin between 1985 and 2005 [14, (64%) female]. Symptoms developed 1 to 393 days (median 5 days) before diagnosis. Presenting symptoms included abdominal pain (59%), vomiting (50%), nausea (40%), early satiety (32%) and anorexia (18%). Diagnosis was made by upper-gastrointestinal radiography in 18 (82%), by computed tomography in 2 (9%) and at laparotomy in 2 (9%). One patient was treated surgically after medical management failed. Mean length of treatment was 65 days (range 13-169), with a mean length of hospitalization of 21 days (range 0-68 days). Conclusion: SMAS usually presents more acutely than chronically with symptoms of small bowel obstruction. Weight loss is not necessary for SMAS development. Prior neurological injury may be a risk factor for development of SMAS. Upper gastrointestinal radiography remains the primary means of diagnosis. SMAS is typically successfully managed medically. Surgical intervention should be reserved for patients' refractory to medical therapy. The expected outcome of SMAS is excellent.
The Use of Financial Market Variables in Forecasting

Financial market indicators can provide valuable information for forecasting macroeconomic developments. In response to the global financial crisis of 2007/2008, the role of financial variables for forecasting has been revisited, and new empirical and theoretical forecasting methods able to explicitly incorporate financial market information have been developed. This roundup discusses characteristics of financial variable movements and the relation to business cycles. It furthermore summarizes some of the new theoretical and empirical approaches at hand for forecasting macroeconomic variables with financial market information, and highlights main challenges forecasters willing to consider financial market information in forecasting exercises have to face.
Adipocytes derived from PA6 cells reliably promote the differentiation of dopaminergic neurons from human embryonic stem cells

The PA6 stromal cell line comprises a heterogeneous population of cells that can induce both mouse and human embryonic stem cells to differentiate into dopaminergic neurons. This ability of PA6 cells has been termed stromal cell‐derived inducing activity (SDIA). The level of SDIA has been found to vary considerably between and within batches of PA6 cells. Not only are the molecular mechanisms that underlie SDIA unknown but also the cell type(s) within the heterogeneous PA6 cultures that underlie SDIA remain poorly defined. In this study, we reveal that adipocytes, which are present within the heterogeneous PA6 cell population, robustly release the factors mediating SDIA. Furthermore, we report that the coculture of human embryonic stem cells with PA6‐derived adipocytes reliably induces their differentiation into midbrain dopaminergic neurons. © 2014 Wiley Periodicals, Inc.
A Framework of De Novo Peptide Sequencing for Multiple Tandem Mass Spectra

With tandem mass spectrometry (MS/MS), spectra can be generated by various fragmentation techniques including collision-induced dissociation (CID), higher-energy collisional dissociation (HCD), electron capture dissociation (ECD), electron transfer dissociation (ETD) and so on. At the same time, de novo sequencing using multiple spectra from the same peptide generated by different fragmentation techniques is becoming popular in proteomics studies. The focus of this study is the use of paired spectra from CID (or HCD) and ECD (or ETD) fragmentation because of the complementarity between them. We present a de novo peptide sequencing framework for multiple tandem mass spectra, and apply it to paired spectra sequencing problem. The performance of the framework on paired spectra is compared to another successful method named pNovo+. The results show that our proposed method outperforms pNovo+ in terms of full length peptide sequencing accuracy on three pairs of experimental datasets, with the accuracy increasing up to 13.6% compared to pNovo+.
Hypoglossal motor neurons display a reduced calcium increase after axotomy in mice with upregulated parvalbumin

Motor neurons that exhibit differences in vulnerability to degeneration have been identified in motor neuron disease and in its animal models. The oculomotor and hypoglossal neurons are regarded as the prototypes of the resistant and susceptible cell types, respectively. Because an increase in the level of intracellular calcium has been proposed as a feature amplifying degenerative processes, we earlier studied the calcium increase in these motor neurons after axotomy in Balb/c mice and demonstrated a correlation between the susceptibility to degeneration and the intracellular calcium increase, with an inverse relation with the calcium buffering capacity, characterized by the parvalbumin or calbindin‐D28k content. Because the differential susceptibility of the cells might also be attributed to their different cellular environments, in the present experiments, with the aim of verifying directly that a higher calcium buffering capacity is indeed responsible for the enhanced resistance, motor neurons were studied in their original milieu in mice with a genetically increased parvalbumin level. The changes in intracellular calcium level of the hypoglossal and oculomotor neurons after axotomy were studied electron microscopically at a 21‐day interval after axotomy, during which time no significant calcium increase was detected in the hypoglossal motor neurons, the response being similar to that of the oculomotor neurons. The hypoglossal motor neurons of the parental mice, used as positive controls, exhibited a transient, significant elevation of calcium. These data provide more direct evidence of the protective role of parvalbumin against the degeneration mediated by a calcium increase in the acute injury of motor neurons. J. Comp. Neurol. 518:1946–1961, 2010. © 2009 Wiley‐Liss, Inc.
Fluconazole-resistant recurrent oral candidiasis in human immunodeficiency virus-positive patients: persistence of Candida albicans strains with the same genotype

Thirty human immunodeficiency virus-positive patients carrying Candida albicans in their oropharynx were treated with fluconazole and were monitored for 90 to 570 days. Fluconazole-resistant C. albicans (MIC, > 32 micrograms/ml) appeared only in seven patients and only after 90 days of treatment corresponding to a total dose of more than 10 g. Resistance was not associated with resistance to other azole derivatives. Susceptible and resistant strains from each patient had the same genotype (as defined by electrophoretic karyotype and restriction fragment length polymorphism). Thus, the resistant strains were selected by the antimycotic treatment from the susceptible strain present in each case.
Systematic Comparison of Operating Reserve Methodologies: Preprint

Operating reserve requirements are a key component of modern power systems, and they contribute to maintaining reliable operations with minimum economic impact. No universal method exists for determining reserve requirements, thus there is a need for a thorough study and performance comparison of the different existing methodologies. Increasing penetrations of variable generation (VG) on electric power systems are posed to increase system uncertainty and variability, thus the need for additional reserve also increases. This paper presents background information on operating reserve and its relationship to VG. A consistent comparison of three methodologies to calculate regulating and flexibility reserve in systems with VG is performed.
Professional Development Needs of Mid-Career Agriculture Teachers

Nationwide, agricultural education faces a shortage of teachers (National Teach Ag Campaign, 2014; Foster, Lawver, & Smith, 2016). To remedy this, both recruitment and retention efforts are necessary. While extensive research in agricultural education has focused on needs of beginning teachers, less research has focused on needs of agriculture teachers at later career stages. As such, the purpose of this phenomenological qualitative study was to explore challenges, activities, and professional development needs of mid-career agriculture teachers, particularly those within the “Experimentation/Activism” and “Reassessment/SelfDoubt” stages identified by Huberman (1989). The study narrowly focused on a census of 35 teachers from across the country who applied for a professional development program designed for mid-career agriculture teachers. Mid-career teachers identified lack of time, course planning, and programmatic expectations as challenges or obstacles. The teachers reported a desire to fulfill professional development needs by networking, reenergizing, and improving stress management. Specifically, teachers reported participating in professional organizations, joining teacher listservs, and networking through the National Association of Agricultural Educators’ Communities of Practice for engagement and support. Findings suggest continued professional development offerings and additional research related to mid-career agriculture teacher wellbeing are warranted.