Miracle-dz/UniFAR-FTUs huggingface dataset:
SLAM contraint pour la localisation dans des environnements partiellement connus

Cet article porte sur la localisation temps reel d'une camera mobile dans un environnement partiellement connu. Ces travaux reposent sur une solution de type SLAM monoculaire et traitent la problematique de derive inherente a ce type de methode en proposant un nouvel ajustement de faisceaux, dit ajustement de faisceaux contraint. Ce dernier permet d'integrer des contraintes geometriques apportees par le modele partiellement connu de la scene. Nous montrons l'apport de cette nouvelle methode sur des applications de Realite Augmentee sur de petits et grands environnements.
Usefulness of Biochemical Screening of Diabetic Patients for Hemochromatosis

We assessed the prevalence of previously unrecognized hemochromatosis among patients in whom diabetes mellitus was diagnosed after the age of 30 yr, and we evaluated the positive predictive value of biochemical screening tests for hemochromatosis in diabetic subjects. Thirty-eight of 572 patients screened (6.6%) had a serum ferritin level >324 μg/L; 16 patients had normal levels on repeat testing. Four patients′ serum ferritin levels fell to <400 μg/L. Seven of 18 patients with a persistently elevated serum ferritin level did not undergo a liver biopsy because of a recognized cause of hyperferritenemia (carcinoma, alcoholism, or systemic lupus erythematosus). The diagnosis of hemochromatosis seemed certain in 1 of 3 patients who were not biopsied for technical reasons. Of 8 patients biopsied, 2 had hemochromatosis, 4 had fatty liver, 1 had hemosiderosis, and 1 had a chronic inflammatory cell infiltrate with no iron deposition. Of 4 patients with a raised transferrin saturation level, 2 had raised serum ferritin levels and hemochromatosis, 1 had raised serum ferritin and hemosiderosis on liver biopsy, and 1 had a normal transferrin saturation level on repeat testing. Two of 3 cases of hemochromatosis had other clinical markers of the condition. Therefore, routine screening of diabetic patients for hemochromatosis is not necessary, because patients with hemochromatosis will often have other clinical features of the disease. When screening diabetic patients for hemochromatosis, it should be remembered that a persistently raised serum ferritin level has a low positive predictive value (16.6%) and that a normal transferrin saturation level does not exclude the diagnosis.
Diabetes Education Kiosks in a Latino Community

Purpose The purpose of this study was to examine the implementation, use, and sustainability of a computerized touch-screen diabetes education kiosk (Diosk) designed to provide “on-demand” education in a predominantly Latino community in South Texas. Methods A pilot study was conducted to examine the implementation, use, and sustainability of the Diosk in 5 settings (eg, clinics, community centers, and pharmacies) serving low-income, low-literacy populations. Both quantitative and qualitative data from embedded computerized usage tracking, user surveys, and key stakeholder interviews were collected and analyzed using descriptive statistics. Results There were more than 5300 uses of the Diosk in the different sites during the 11-month study. The majority of users were female, between the ages of 36 and 64 years, and Latino, and they identified themselves as having or being at risk for type 2 diabetes. Several challenges were faced in maintaining the Diosk during the study, such as organizational capacity to host wireless Internet and establishing “office champions” responsible for overseeing the Diosk. At the end of the study, 3 of the 5 sites committed to sustaining the Diosk on their own. Conclusions This pilot study testing the feasibility and acceptability of the Diosk demonstrated that a Diosk can be implemented, used, and sustained in a population with high rates of diabetes and limited prior use of disease management programs. Computerized technology offers one solution to expanding the reach of diabetes education through easily accessible community and clinical settings.
Palladin is expressed preferentially in excitatory terminals in the rat central nervous system

Palladin is a recently described intracellular protein associated with the actin cytoskeleton and cell adhesion in fibroblasts. In Western and Northern blot analyses, palladin expression is ubiquitous in embryonic mice, but it is down‐regulated dramatically in most adult tissues. Significant amounts of palladin persist in the brain of adult rodents, as assessed by Western blot analysis. With this work, we extend preliminary observations and determine the overall distribution and subcellular location of palladin throughout the rat brain. In sagittal and coronal sections of the central nervous system, immunostain for palladin is present throughout the brain and spinal cord, but not uniformly. The densest regions of immunostain include the olfactory bulb, cerebral and cerebellar cortex, hippocampus, amygdala, superior colliculus, and superficial laminae of the spinal dorsal horn. Because immunostain characteristically is punctate, we performed double staining for palladin and the presynaptic marker synaptophysin. Confocal microscopy showed that palladin‐immunopositive puncta are also immunopositive for synaptophysin; the proportion of synaptophysin‐immunopositive puncta that also stained for palladin ranged from 100% of mossy fiber terminals in field CA3 of the hippocampus and in the cerebellar cortex to 60–70% of terminals in the cerebral cortex, striatum, and spinal dorsal horn. The presence of palladin in synaptic terminals was confirmed by electron microscopy. Because immunostained terminals commonly establish asymmetric synapses, the selectivity of palladin expression in synaptic terminals was tested by double staining for palladin and γ‐aminobutyric acid. The modest level of colocalization in this material at both the light microscopic and electron microscopic levels suggests a selectivity of palladin for terminals that release excitatory neurotransmitters. As concomitant work in cell cultures has shown that palladin participates in axonal development and migration, the present results suggest that palladin persists at excitatory synapses of the adult nervous system. J. Comp. Neurol. 436:211–224, 2001. © 2001 Wiley‐Liss, Inc.
Scheduling In Distributed Systems

In this paper we take a look at three decades of the history and evolution of distributed data processing systems. We consider how allocation of resources to tasks, i.e. scheduling, is done in three systems and study how system goals influence scheduler design and possible scheduling optimizations. We start by examining the first general-purpose distributed computing system Condor [1], continue with the pioneering parallel relational database Gamma [2], and finally introduce contemporary distributed system Map-Reduce [3]. The concepts behind each of the systems are representative for general computing platforms, parallel databases, and Map-Reduce platforms correspondingly.
Immobilization of Lactase from Kluyveromyces lactis Greatly Reduces the Inhibition Promoted by Glucose. Full Hydrolysis of Lactose in Milk

The kinetic constants (Km, Vmax, and inhibition constants for the different products) of soluble and different immobilized preparations of β‐galactosidase from Kluyveromyces lactis were determined. For the soluble enzyme, the Km was 3.6 mM, while the competitive inhibition constant by galactose was 45 mM and the noncompetitive one by glucose was 758 mM. The immobilized preparations conserved similar values of Km and competitive inhibition, but in some instances much higher values for the noncompetitive inhibition constants were obtained. Thus, when glyoxyl or glutaraldehyde supports were used to immobilize the enzyme, the noncompetitive inhibition was greatly reduced (Ki ≈ 15 000 and >40 000 mM, respectively), whereas when using sugar chains to immobilize the enzyme the behavior had an effect very similar to the soluble enzyme. These results presented a great practical relevance. While using the soluble enzyme or the enzyme immobilized via the sugar chain as biocatalysts in the hydrolysis of lactose in milk only around 90% of the substrate was hydrolyzed, by using of these the enzyme immobilized via the glyoxyl or the glutaraldehyde groups, more than 99% of the lactose in milk was hydrolyzed.
Role for DNA replication in beta-globin gene activation

Transcriptional activation of the Xenopus laevis beta-globin gene requires the synergistic action of the simian virus 40 enhancer and DNA replication in DEAE-dextran-mediated HeLa cell transfections. Replication does not act through covalent modification of the template, since its requirement was not obviated by the prior replication of the transfected DNA in eucaryotic cells. Transfection of DNA over a 100-fold range demonstrates that replication does not contribute to gene activation simply increasing template copy number. Furthermore, in cotransfections of replicating and nonreplicating constructs, only replicating templates were transcribed. Replication is not simply a requirement of chromatin assembly, since even unreplicated templates generated nucleosomal ladders. Stimulation of beta-globin transcription by DNA replication, though less marked, was also observed in calcium phosphate transfections. We interpret these results as revealing a dynamic role for replication in gene activation.
Sequence-independent characterization of viruses based on the pattern of viral small RNAs produced by the host

Virus surveillance in vector insects is potentially of great beneﬁt to public health. Large-scale sequencing of small and long RNAs has previously been used to detect viruses, but without any formal comparison of different strategies. Furthermore, the identiﬁca-tion of viral sequences largely depends on similarity searches against reference databases. Here, we developed a sequence-independent strategy based on virus-derived small RNAs produced by the host response, such as the RNA interference pathway. In insects, we compared sequences of small and long RNAs, demonstrating that viral sequences are enriched in the small RNA fraction. We also noted that the small RNA size proﬁle is a unique signature for each virus and can be used to identify novel viral sequences without known relatives in reference databases. Using this strategy, we characterized six novel viruses in the viromes of laboratory fruit ﬂies and wild populations of two insect vectors: mosquitoes and sandﬂies. We also show that the small RNA proﬁle could be used to infer viral tropism for ovaries among other aspects of virus biology. Additionally, our results suggest that virus detection utilizing small RNAs can also be applied to vertebrates, although not as efﬁciently as to plants and insects.
Combined tibial lengthening and ankle arthrodesis for patients with certain type of sequelae of poliomyelitis

Purpose: Following far advancement of modern medicine and technology, functional disability in a certain type of sequelae of poliomyelitis may be effectively improved. Methods: Eight consecutive adult patients with unilateral sequelae of poliomyelitis were treated. These patients had shortened lower extremity of an average of 4.8 cm (range, 4.0–5.5 cm) in the lesion side. Muscle power of the ipsilateral knee was nearly intact (grade 4 or 5) but the ankle extension was completely flaccid. The tibia was osteotomized and lengthened with external fixation. Consequently, all external fixators were converted to plates supplemented with autogenous corticocancellous bone graft and bone graft substitute. Ankle arthrodesis was performed concomitantly. Results: Seven patients were followed up for an average of 3.7 years (range, 2.2–5.4 years). All seven lengthened sites healed with an average union time of 3.9 months (range, 3.5–4.5 months) after plating. One ankle infection occurred. Gait function significantly improved by modified Mazur scoring evaluation (p = 0.02). At the latest follow-up, all patients had a minimal or unnoticed limp in level walking. Conclusion: The described combined techniques may be an excellent alternate for treating selected patients with sequelae of poliomyelitis. The procedure is not complex but the efficiency is extremely prominent.
Orienting and maintenance of spatial attention in audition and vision: an event‐related brain potential study

We examined the effects of orienting and maintenance of attention on performance and event‐related brain potentials (ERPs) in audition and vision. Our subjects selectively attended to sounds or pictures in one location (Maintenance of attention) or alternated the focus of their auditory or visual attention between left and right locations (Orienting of attention) in order to detect and press a response button to infrequent targets among the attended stimuli. Reaction times were longer in the Auditory Orienting condition and hit rates were lower and false alarm rates higher in the Visual Orienting condition than in the corresponding Maintenance conditions. Comparison of ERPs to the attended and unattended stimuli in the Auditory and Visual Orienting and Maintenance conditions revealed attention‐related modulations of ERPs. In each modality, ERPs to attended stimuli were negatively displaced in relation to unattended stimuli at 100–250 ms from stimulus onset. These negative differences (Nds) showed modality‐specific distributions and they were larger over the hemisphere contralateral to the attended sounds and pictures than over the ipsilateral hemisphere. Moreover, the Nd was larger in the Auditory Orienting condition than in the Auditory Maintenance condition, while no such difference was observed in the visual modality. In addition to the Nd, attended visual stimuli elicited a late positive response (LPR) in both Orienting and Maintenance conditions. In contrast to our recent functional magnetic resonance imaging (fMRI) study employing the same experimental paradigm and indicating orienting‐related activity in the frontal and parietal cortices, no ERP responses specifically related to orienting were found in either modality.
Rabies preexposure prophylaxis with human diploid cell rabies vaccine: a dose-response study.

Recent studies suggest that human diploid cell rabies vaccine (HDCV) may not always produce acceptable titers after intradermal (id) preexposure prophylaxis. To stimulate accidental deviation from the recommended route of administration and to determine the immunogenicity of smaller-than-recommended doses of HDCV, we injected each of 154 persons either intramuscularly (im) with 100%, 10%, or 3% of the standard im dose of vaccine or id with 10%, 3% or 1% of the standard im dose. Seroconversion (titers of antibody greater than or equal to 1:11) was found in all subjects at 49 and 90 days after vaccination. Titers were higher for subjects receiving 100% of the recommended dose im than for those receiving 10% of this dose id (P less than .01); these titers in turn were higher than those from persons receiving smaller doses (P less than .05). Persons receiving 10% or 3% of the standard im dose had lower titers on day 49 than did those receiving the same dose id (P less than .05).
Uncovering the Structure of Criminal Organizations by Community Analysis: The Infinito Network

Criminal organizations tend to be clustered to reduce risks of detection and information leaks. Yet, the literature has so far neglected to explore the relevance of subgroups for their internal structure. The paper focuses on a case study drawing from a large law enforcement operation ("Operazione Infinito"). It applies methods of community analysis to explore the structure of a 'Ndrangheta (a mafia from Calabria, a southern Italian region) network representing the individuals' co-participation in meetings. The results show that the network is significantly clustered and that communities are partially associated with the internal organization of the 'Ndrangheta into different "locali" (similar to mafia families). The implications of these findings on the interpretation of the structure and functioning of the criminal network are discussed.
Hypergraph Modeling and Approximation Algorithms for the Minimum Length Link Scheduling in Multiuser MIMO Networks

This paper investigates the problem of the minimum length link scheduling (MLLS) in multiuser MIMO (MU-MIMO) networks. Generally, in the networks with MU-MIMO capability, the number of concurrent transmissions can be as large as that of antenna elements at the receiver. As a result, link interference is no longer binary but demonstrates a strong correlation among multiple links, which cannot be captured by the conventional conflict graph interference model. Hence, we propose a novel hypergraph interference model, which can accurately and efficiently characterize the relationship of multiple interferences induced by concurrent transmissions, and provide a tractable formalization of the minimum length link scheduling in MU-MIMO networks (MU-MIMO MLLS). Afterwards, we prove that the MU-MIMO MLLS problem is NP-hard and introduce two approximation algorithms to find the near-optimal feasible schedule. Finally, extensive simulation experiments are presented.
Effects of atorvastatin on coagulation parameters and homocysteine in patients with primary hypercholesterolemia.

BACKGROUND The mechanism of the antithrombotic action of statins is unclear. We evaluated the effects of atorvastatin on the coagulation parameters and homocysteine levels of patients with primary hypercholesterolemia. MATERIALS AND METHODS Forty-four patients with primary hypercholesterolemia were treated with atorvastatin 10 mg/d for 24 weeks at Adnan Menderes University Medical Faculty, Division of Hematology, Aydin, Turkey. We evaluated the effects of atorvastatin on homocysteine; lipid parameters such as total cholesterol, low-density-lipoprotein (LDL) cholesterol, very-low-density-lipoprotein (VLDL) cholesterol, triglycerides, high-density-lipoprotein (HDL) cholesterol, lipoprotein (a), apolipoprotein Al and apolipoprotein B; and coagulation parameters such as fibrinogen, antithrombin-III, protein C, protein S, von Willebrand factor, D-dimer, partial thromboplastin time and prothrombin time; and hematological parameters such as hemoglobin, white blood cell and platelet counts, vitamin B12 and folic acid. RESULTS Atorvastatin significantly decreased the levels of total cholesterol, LDL cholesterol (p < 0.001), VLDL cholesterol, triglycerides and apo B (p < 0.001). The level of HDL cholesterol significantly increased with atorvastatin treatment (p < 0.001). Atorvastatin significantly increased the levels of fibrinogen (p < 0.001), but it had no effect on other coagulation factors and homocysteine (p > 0.05). After treatment, while vitamin B12 levels significantly increased (p < 0.05), other hematological parameters were not changed with atorvastatin (p > 0.05). CONCLUSION Although there were beneficial effects of atorvastatin on lipid parameters, atorvastatin did not significantly change the level of homocysteine and hematological, and coagulation parameters, with the exception of fibrinogen and vitamin B12 levels.
New proposal for eliminating interferences in a radar system. Lobes at 45.5° and 24°

In this work we present a new proposal to initialize the weights in a Backpropagation Neuronal Network using the coefficients from a FIR Low-Pass Filter, to introduce a null in the radiation pattern in a seven- element array of antennas to eliminate interferences in a radar system. A radar system needs to eliminate the directional noise in order to obtain a cleaner signal. The method used to eliminate this kind of noise (jitter) has to be adaptive because the objective is in constant movement, therefore, the adaptation time must be as fast as possible. Our work is based on the window method to reduce the secondary lobes in fixed arrays of antennas. We modify the radiation pattern by introducing a null at 45.5° which corresponds to the secondary lobe where the interference is presented. This is achieved when we create windows from several FIR Low-Pass Filters. The coefficients of these filters are used to initialize the weight vectors of a Backpropagation Neural Network which performs the adaptive process to obtain the final parameters to achieve the noise elimination. For testing our proposal we calculate the Mean Square Error (MSE), the Signal Noise Relation (SNR) and we graphed the Radiation Pattern. In addition we calculated the Cross Correlation Index, in each iteration, between the desired signal and our results. With this method we reduced the number of iterations required by the process.
Regulation of homologous recombinational repair by lamin B1 in radiation‐induced DNA damage

DNA double‐strand breaks (DSBs) are the major lethal lesion induced by ionizing radiation (IR). RAD51‐dependent homologous recombination (HR) is one of the most important pathways in DSB repair and genome integrity maintenance. However, the mechanism of HR regulation by RAD51 remains unclear. To understand the mechanism of RAD51‐dependent HR, we searched for interacting partners of RAD51 by a proteomics analysis and identified lamin B1 in human cells. Lamins are nuclear lamina proteins that play important roles in the structural organization of the nucleus and the regulation of chromosome functions. Immunoblotting analyses revealed that siRNA‐mediated lamin B1 depletion repressed the DNA damage‐dependent increase of RAD51 after IR. The repression was abolished by the proteasome inhibitor MG132, suggesting that ***lamin B1 stabilizes RAD51 by preventing proteasome‐mediated degradation in cells with IR‐induced DNA damage. We also showed that lamin B1 depletion repressed RAD51 focus formation and decreased the survival rates after IR. On the basis of these results, we propose that lamin B1 promotes DSB repair and cell survival by maintaining the RAD51 protein levels for HR upon DSB induction after IR. —Liu, N. ‐A. , Sun, J., Kono, K. , Horikoshi, Y. , Ikura, T. , Tong, X. , Haraguchi, T. , Tashiro, S. Regulation of homologous recombinational repair by lamin B1 in radiation‐induced DNA damage. FASEB J. 29, 2514‐2525 (2015). www.fasebj. org
A Survey of Abnormal Traffic Information Detection and Transmission Mechanisms in VSNs

With the continuously increasing number of vehicles, particularly in cities, there are more and more abnormal traffic events occurring on road, which easily cause road congestion. In vehicular sensor networks (VSNs), with the intervehicle cooperative communication, vehicle nodes can detect the abnormal traffic events and disseminate the related information to the interesting vehicles or persons. This paper gives out a survey of the abnormal traffic information detection and transmission mechanisms in VSNs. Firstly, we overview the origin, characteristic, and application of VSNs. Meanwhile, the definition and features of traffic abnormal information are also introduced and presented. Then, we put more energy on elaborating the existing information detection and transmission mechanisms based on VSNs. Finally, the challenges and problems are discussed.