Miracle-dz/UniFAR-FTUs huggingface dataset:
Parasitic and enteric bacterial infections among food handlers in tourist-area restaurants and educational-institution cafeterias, Sai-Yok District, Kanchanaburi Province, Thailand.

Abstract This study aimed to determine the health status of food handlers working in the cafeterias ofeducational institutions, and those working in the restaurants of a tourist area in Sai-Yok District,Kanchanaburi Province, Thailand. A total of 273 stool samples were collected: 29.3% (80/273) fromfood handlers in the educational institutions, and 70.7% (193/273) from food handlers in touristarearestaurants. In all, 266 (97.4%) participants agreed to complete the study questionnaire. Thestool samples collected were examined by direct smear and Kato-Katz modified thick-smear, andcultured for bacterial infections by agar plate method. The prevalence of intestinal parasites was10.3% (28/273). Among these, hookworm was the most common (70.0%), followed by Entamoeba coli(10.0%), Trichuris trichiura (10.0%), Blastocystis hominis (3.3%), Giardia lamblia (3.3%), and Endolimaxnana (3.3%). All stool cultures tested negative for enteropathogenic bacteria. Helminth infectionswere less prevalent among the food handlers from the educational institutions. A medical check-upprogram with health education could improve workers’ health status. Keywords: food handler, intestinal parasites, enteropathogenic bacteria, Kanchanaburi, Thailand
Allogeneic Bone Marrow Transplantation in Children With Chronic Myelogenous Leukemia

Purpose To determine the outcome of children undergoing allogeneic bone marrow transplantation for chronic myelogenous leukemia (CML) at the authors' institution. Patients and Methods Between 1985 and 1999, 18 allogeneic bone marrow transplantations were performed in 17 patients with CML at the Hospital for Sick Children in Toronto. Median age at diagnosis was 9.5 years (range 3–17). Fourteen patients had disease in the first chronic phase, one had disease in the second chronic phase, and two had disease in the accelerated phase. Preparative regimens varied, with radiation-based protocols used in eight patients. Thirteen donors were related (11 matched, 2 mismatched); four were unrelated (2 matched, 2 mismatched). Patients received T–cell-replete bone marrow a median of 7.5 months (range 2.2–22) from diagnosis. A median of 3.0 × 108/kg nucleated cells was infused (range 1.6–6.7). Graft-versus-host disease (GVHD) prophylaxis consisted of cyclosporine and methotrexate in 13 children, cyclosporine in three, and methotrexate in one. Results Primary graft failure occurred in one patient. Grade 2 acute GVHD or more developed in 11 of the 17 children (64%; grade 2 in 4, grade 3 in 7). Chronic GVHD occurred in 6 of the 16 patients at risk (37.5%; 5 extensive, 1 localized). No patient experienced overt or cytogenetic relapse. There were two deaths (12%): one from acute GVHD and cytomegalovirus pneumonia and the other from chronic GVHD. Probability of 5-year event-free survival was 87 ± 9%. Conclusions These results strongly support the practice of allotransplantation in children with CML, even in the setting of advanced disease and histoincompatibility. Efforts should be aimed at reducing the transplantation-related death rate.
Public Expenditures, Taxes, Federal Transfers, and Endogenous Growth

This paper extends the Barro (1990) model with single aggregate government spending and one flat income tax to include public expenditures and taxes by multiple levels of government. It derives the rate of endogenous growth and, with both simulations and special examples, examines how that rate changes with respect to federal income tax, local taxes, and federal transfers. It also discusses the growth and welfare-maximizing choices of taxes and federal transfers.
Effects of Thioredoxin‐1 on Neurogenesis after Brain Ischemia/Reperfusion Injury

Thioredoxin (Trx) is a 12-kDa protein ubiquitously expressed in all living cells that fulfills a variety of biological functions related to cell proliferation and apoptosis [1]. It is characterized by the highly conserved reduction/oxidation (redox)-active site sequence Trp-Cys-Gly-Pro-Cys-Lys. Trx acts as a powerful antioxidant and plays an important role in maintaining critical protein thiols in the reduced state. Trx-1 has been shown to have neuroprotective effects on both brain ischemia and excitotoxic hippocampal injury in transgenic mice overexpressing human Trx-1 [2]. In the adult brain, new neurons are continuously generated in the subventricular zone (SVZ) and dentate gyrus (DG) and brain insults such as cerebral ischemia, which cause neuronal death, lead to increased neurogenesis in the SVZ and DG. Evidences have shown that these stroke-induced newborn precursors could migrate into the severely damaged striatum and develop into mature neurons [3]. This process is modulated by many factors and signals. It was reported that Trx-1 could promote neurite growth by activation of transcription factors [4], but the exact effect of Trx-1 on neurogenesis after ischemia is still unknown. Focal cerebral ischemia in adult male Sprague-Dawley rats (weighing 220–240 g) was induced by middle cerebral artery occlusion (MCAO) for 90 min with an intraluminal filament according to the method previously described by Longa [5]. Recombinant human Trx-1 (RhTrx-1) (200 lg/kg) was administered intraventricularly at 24, 48, and 72 h after reperfusion. The rats were administered 5-bromo-2′-deoxyuridine (BrdU) intraperitoneally 100 mg/kg daily for 5 days at 24 h after reperfusion. At 7 days after reperfusion, Nissl staining in hippocampus showed extensive neuronal loss, but rhTrx-1 administration could attenuate this injury (Figure 1). This is the first evidence that intraventricularlly administered rhTrx-1 could exert neuroprotective effect on brain ischemia/reperfusion (I/R) injury in rats. In our study, we also examined the effect of rhTrx-1 on neurogenesis after brain I/R injury. RhTrx-1 treatment increased BrdU cells nearly 2-fold in the SVZ compared with I/R group at 7 days (Figure 2A), and this elevation persisted significantly even at 14 days after I/R. Most of these BrdU cells were BrdU/Dcx double-labeled cells. The number of BrdU/NeuN double-labeled cells also increased after MCAO and Trx-1 treatment group showed Figure 1 Effect of rhTrx-1 on hippocampal neurons survival in rats subjected to 7 days of reperfusion after 90-min middle cerebral artery occlusion (MCAO) (Nissl staining). The survival neurons in MCAO group (n = 5) and rhTrx-1 treatment group rats (n = 5) were statistically different (P < 0.01). Data were expressed as mean SD. Data were analyzed by One-way ANOVA.
Stabilisation Activity in Italian IPOs

Commission Regulation (EC) No 2273/2003 regulates price stabilisation activities for equity initial public offerings (IPOs) in Europe as a form of permitted market manipulation. To test the actual practices and effects of stabilisation we empirically analyse the support provided by underwriters of 141 Italian IPOs from 2000 through to 2008. We find that underwriters support the share prices not only by short covering, but also by posting pure stabilisation bids. Pure short covering is mostly used by more reputable underwriters for IPOs with higher institutional participation and more secondary shares in the offer, whereas the opposite is true for pure stabilisation IPOs. We try to identify some patterns in underwriters’ aftermarket activities and analyse the extent to which the stabilisation activity, permitted for four weeks after trading begins, produces temporary or permanent effects on share prices.
Metadata Management for Knowledge Discovery IT 4 BI MSc thesis

Over the last years, knowledge discovery for Big Data has grown immensely and the requirement for automated user assistant techniques for the knowledge discovery have attracted more focus. Machine-processable metadata is needed in order to support the automation so that the automated systems are able to gain access to relevant information essential for the knowledge discovery processes. The automated systems apply to numerous mining algorithm and diverse data sources. None of the existing approaches proposes a flexible and extensible model of the knowledge discovery metadata artifacts that is reusable in various systems and for varied purposes as the metadata is typically stored in ad-hoc manners. Therefore, in this thesis, we propose a comprehensive, generic and extensible metamodel to enable automated intelligent discovery assistant. Aiming at semantic-awareness and the incorporation of external resources, we present the metamodel as an RDF formalization. Moreover, we provide a metadata repository where the user can access, manipulate and explore the metadata. Finally, we discuss the benefits of the approach, and present directions for the future work.
Has Globalization Gone Too Far

The process that has come to be called "globalization" is exposing a deep fault line between groups who have the skills and mobility to flourish in global markets and those who either don't have these advantages or perceive the expansion of unregulated markets as inimical to social stability and deeply held norms. The result is severe tension between the market and social groups such as workers, pensioners, and environmentalists, with governments stuck in the middle. The most serious challenge for the world economy in the years ahead lies in making globalization compatible with domestic social and political stability—or to put it even more directly, in ensuring that international economic integration does not contribute to domestic social disintegration.
The Online Visual Group Formation of the Far Right: A Cognitive-Historical Case Study of the British National Party

This article investigates how the European far right, exemplified by the British National Party (BNP) uses images and other semiotic resources in online group formation. The data consists of a corpus containing all images occurring in articles published on the BNP website between May 2010 and March 2012. Flag elements are used as entry point to the analysis due to their high frequency in the corpus. The article proposes a cognitive-historical approach to Critical Discourse Analysis drawing on Cognitive Linguistics and the Discourse-Historical Approach. The analysis shows that images in BNP articles are not merely accessory features to text but that they send out ideological messages on their own and that they to a certain degree express what cannot be said using text. Flag images show how the BNP has undergone a visual transformation in the last decade, but also that the party constructs out-groups with anti-left and Islamophobic undertones.
Constrained Shape Control of Bicubic B-Spline Surfaces by Knots

Constrained modification of B-spline surfaces is essential in geometric design. Modification tools by purely knot alteration are presented in this paper: moving an isoparametric line to a specified location and dragging a point of the surface to a predefined point. Both methods yield smoother change than the well-known control point repositioning, while in the first case symmetric bodies can be deformed in a constrained way by automatically preserving their symmetry. Since the modified surface remains in the original convex hull, these techniques can be useful tools in the fine tuning phase, when users do not want to change the overall shape of the body
Real options valuation: the new frontier in R&D project evaluation?

The real options approach has recently received growing attention in R&D and Technology Management research. Recent empirical findings by Ellis (1997) and Busby and Pitts (1997) also report growing attention and use in practical investment decisions. However, there is a certain concern about the applicability to a wide range of R&D related problems. The theoretical base behind options valuation is derived from the capital markets and thus assumes market conditions that are closer to the theoretical construct of ‘perfect competition’ than most other settings. Even under these conditions, several assumptions made and difficulties left are subject to controversial discussions. Of course these problems even gain importance when the R&D environment with its discontinuities and lack of regulation or institutionalized trade is assumed. This paper describes some basic properties of the real options approach and sheds light on existing problems for the application in R&D project evaluation. On the other hand, roads to application of the method are shown using the Geske model of option evaluation. One main goal of the paper is to broaden and deepen the discussion on real option models in R&D and Technology Management, which has in some cases been limited to stressing the advantages of the method rather than reflecting on applicability and concrete way of application of the method.
Synthesis of poly‐O‐tert‐butyl‐L‐serine and poly‐L‐serine

The synthesis of polymers containing O‐tert‐butyl‐L‐serine, O‐tert‐butyl‐DL‐serine, L‐serine, and DL‐serine is reported. The N‐benzyloxycarbonyl‐(L or DL)‐serine benzyl ester was used to synthesize the corresponding N‐benzyloxycarbonyl‐O‐tert‐butyl‐(Lor DL)‐serine benzyl ester. Catalytic hydrogenation of this material gave O‐tert‐butyl‐(Lor DL)‐serine. The reaction of O‐tert‐butyl‐(Lor DL)‐serine with phosgene produced the corresponding N‐carboxyanhydrides. The kinetics of polymerization of N‐carboxyanhydrides were investigated to facilitate, the preparation of block copolymers. The O‐tert‐butyl blocking group was removed from polymers by treatment with HCl and HBr in benzene. Both high molecular weight (water‐insoluble) and low molecular weight (water‐soluble) homopolymers have been prepared, as well as water‐soluble block copolymers of the type (DL‐serine)x (L‐serine)y, (DL‐serine)z.
Hospice news

The first national Clinical Practice Guidelines for Quality Palliative Care, released in April 2004, is on the Web and available for download. The guidelines were developed by experts across the field to assist the rapidly growing number of palliative care programs established in hospitals, nursing homes, hospices, and health systems deliver high-quality, state-ofthe-art care to seriously ill patients and their families. “These guidelines couldn’t be more timely, with increasing numbers of Americans who suffer from advanced, chronic illness and need the relief and support that palliative care provides,” said Charles von Gunten, MD, PhD, Medical Director at the Center for Palliative Studies in San Diego. “The new clinical practice guidelines will enable palliative care specialists and other healthcare professionals to deliver the highest quality palliative care in all settings to this rapidly expanding patient population. ” Healthcare professionals delivering palliative care can use the guidelines to provide specialized care to their sickest and most complex patients, resulting in higher patient/family satisfaction with the care they receive and with the healthcare system in general. The guidelines combine the expertise of leading organizations and their members, including more than 50,000 healthcare professionals and consumers from all 50 states, and grow out of more than 20 years of research and experience into what kind of care best meets the needs of patients with advanced chronic or lifethreatening illnesses. Eight key areas are covered in detail, including the following:
Nutzergenerierte Reisewarnungen auf Twitter: Eine Explorative Analyse / User-Generated Travel Warnings on Twitter: An Explorative Analysis

Zusammenfassung Viele internationale auswärtige Ämter nutzen die Online-Plattform Twitter mittlerweile als Kanal für Reisewarnungen. Dieser neue Informationskanal erlaubt den Betrieb von Anwendungen, die einem breiten Publikum aktuelle, hochqualitative Reiserisikoinformationen zugänglich machen. Unsere explorative Forschung hat das Ziel, die Rolle der Informationsquelle und Zielgruppe einer solchen Anwendung zu untersuchen. Die Resultate unserer Analyse zeigen keine substantiellen Hinweise darauf, dass nutzergenerierte Inhalte per se ungeeignet als Informationsquelle sind. Zusätzlich zeigt unsere Analyse, dass Vielreisende eine besonders interessante Zielgruppe sind. Summary Online platform Twitter, has been recognized by international foreign offices as an outlet for travel warning. This new channel of information allows for the creation of applications that bring current and high quality travel risk information to the mainstream. Our explorative research aims at investigating the role of the information source and target audience of such an application. The results of our analysis show no substantial evidence that user-generated travel risk information would be per se unsuitable as an information source. Further, our analysis revealed that frequent travelers might be of special interest as a target group for the application.
The Formation of Employee Satisfaction with Airline Information Systems

ABSTRACT Ensuring end users (i.e., employees) are able and willing to use advanced airline information systems (IS) is critical for airlines to gain operational efficiency and passenger satisfaction. Despite the importance of end-user satisfaction (EUS) with IS, there have been no prior studies examining the extent of the applicability of previous theoretical constructs of EUS in the context of airline IS. We integrate the major antecedents of EUS into a proposed EUS model for airline IS and collect data via a questionnaire survey from service operational employees of eight airlines to test the model. The results indicate that although the actual and expected performance of an IS are two determinants of EUS, equitable needs fulfillment has the largest impact on EUS. Conversely, we find that equity sensitivity and involvement congruence have no significant impact on EUS. This article contributes to research by identifying the factors that yield EUS with airline IS and provides managerial insights on successful IS management in the airline industry.
Refining Traceability Links between Code and Software Documents

Recovering traceability links between source code and software document can be very helpful for Software Maintenance and Software Reuse. Existing work has already achieved good results in extracting code elements (classes, methods, etc.) from software documents. However, it will lead to a lot of noise links if we link a document to all the code elements existing in it. In this paper, we propose an approach to identify the contextual code elements and the salient code elements in a software document, then we can weight the traceability links between source code and software document so that those noise traceability links can be filtered effectively. We measure the saliency of each code element in a document with four kinds of document-related features and three kinds of code-related features, and we adopt TransR-based code embedding technology to evaluate the distance between code elements. In the experiments, we get a precision of 70.7% in recognizing salient code elements of StackOverflow answer documents, which is more than 12% improvement compared with Rigby's work. At the same time, we can filter about 56.5%~69.3% noise traceability links compared with the RecoDoc approach. It will improve the quality of traceability links between source code and related software documents.
The effect of phenylpyruvate on pyruvate metabolism in rat brain.

1. The effect of phenylalanine and phenylpyruvate on the metabolism of pyruvate by isolated mitochondria from rat brain was investigated. 2. Phenylpyruvate inhibited the fixation of H(14)CO(3) (-) in the presence of pyruvate by intact rat brain mitochondria, whereas phenylalanine and other metabolites of this amino acid had no inhibitory effect on this process. 3. Pyruvate carboxylase activity in freeze-dried rat brain mitochondrial preparations was also inhibited only by phenylpyruvate, and a ;mixed type' inhibition was observed. 4. The K(m) for pyruvate of rat brain pyruvate carboxylase was about 0.2mm. 5. The concentration of phenylpyruvate required for a 50% inhibition of H(14)CO(3) (-) fixation by the intact mitochondria and of pyruvate carboxylase activity was dependent on the concentration of pyruvate used in the incubation medium. 6. The possible significance of inhibition of pyruvate carboxylase activity by phenylpyruvate in the brains of phenylketonuric patients is discussed.
Economics of Dairy Farming in Turkey

In this study dairy farming activities in Turkey are employed to prove that small-scale agricultural production is disappearing rapidly due to costly investment and mechanization needs. For that purpose the cost structure and the investment needs in starting a dairy farm are analyzed. The results show that the capital requirements of building a dairy farm with optimal capacity are hard to reach for small farmers unless a system of marketing and production agricultural cooperatives and/or institutions are organized.
Is a long-term aerobic plus resistance training program feasible for and effective on metabolic profiles in type 2 diabetic patients?

Aerobic physical activity is a major therapeutic modality for type 2 diabetes (1,2). It is well known that regular aerobic exercise produces beneficial effects on glycemic control, insulin sensitivity, lipid abnormalities, and hypertension (3,4). On the other hand, several recent studies (5,6) have demonstrated the beneficial effect of resistance exercise in diabetes, and these results should encourage its practice because of the increasing number of sedentary, older, and obese people in industrialized countries. In fact, this is particularly important in the case of individuals who may be noncompliant with aerobic exercise. To prove the effectiveness of resistance training, a recent study (7) showed the positive effects of prescribed and supervised high-intensity resistance training for 16 weeks in high-risk older adults with type 2 diabetes, resulting in improved glycemic and metabolic control. Similarly, 16 weeks of resistance plus aerobic training is reported to enhance glucose disposal in postmenopausal women with type 2 diabetes (8). Both of these studies evaluate the effect of relatively short-period physical training but neither investigates prolonged resistance exercise combined with aerobic training in diabetic people. We therefore investigated the long-term effects (1 year) of prescribed and supervised combined aerobic and resistance training on glycemic control, cardiovascular risk factors, and body composition in type 2 diabetic patients. Physical examination was performed to detect the presence and degree of complications as well as to determine any orthopedic limitations. After …
Comparative analysis of group scheduling heuristics in a flow shop cellular system

Investigates group scheduling heuristics in a flow shop cellular system with two types of order shipment environment: permitted early shipment (PES) and forbidden early shipment (FES). Once an order is completed in the PES environment, it leaves the system without delay. In the FES environment, however, the suppliers must deliver materials to the system on a just‐in‐time basis; and a completed order cannot leave the system earlier than the customer has specified. The FES environment therefore captures many of the features of the currently popular just‐in‐time (JIT) approach to manufacturing. Examines shop factors such as the order shipment environment, demand pattern variability, and order release policy. Shows that the performance of heuristics in the FES environment differs from their performance in the PES environment, except for tardiness‐related measures. Identifies the best performing heuristics, which can provide guidance for schedulers or decision makers in the selection of preferable heuristics.