Miracle-dz/UniFAR-FTUs huggingface dataset:
Research of the input-parallel output-series inductive power transfer system

Input-parallel output-series (IPOS) inductive power transfer (IPT) system is suitable for high output voltage, high power or flexible output power levels applications. This paper makes a thorough study of the IPOS IPT system consisting of two modules. Considering the transformation of each module's equivalent load, the cross coupling between two transformers in IPOS system, the analysis of the output voltage gain and the input impedance is performed in the paper. This paper also researches the placement of the two transformer to reduce the cross coupling between the two contactless transformers. A 7 kW IPOS IPT prototype comprising two modules with interleaving control technique is fabricated with the maximum efficiency reaching 95.4%.
Optimale Operatoren in der Digitalen Bildverarbeitung

Eine neuartige Methode zur optimalen Wahl von Filteroperatoren wird vorgestellt. Dabei konnen sowohl einzelne Filter als auch Filterfamilien mit linearen und nichtlinearen Optimalitatskriterien mittels unterschiedlicher, gewichteter Normen im Wellenzahlraum behandelt werden. Es konnen Flieskomma- oder Festkommakoeffizienten von Filtern mit beliebigen Tragern optimiert werden. In verschiedenen Applikationsbeispielen werden Filter u.a. nach Isotropie, Rotationsinvarianz oder Betragsgenauigkeit optimiert und die Ergebnisse diskutiert. Zumeist sind Verminderungen der Fehler gegenuber ublichen Parameterwahlen um mehr als eine Grosenordnung zu verzeichnen. Untersuchungen der bekannten Strukturtensormethode zeigen, das durch den Einsatz optimaler Filter Verschiebungsschatzungen in zweierlei Hinsicht verbessert werden. Erstens werden Fehler um ca. zwei Grosenordnungen vermindert, zweitens ist eine erhohte Stabilitat gegenuber Rauschen zu verzeichnen. Die gesteigerte Leistungsfahigkeit der Methode wird anhand einer Objektverfolgung demonstriert. Eine neue explizite Diskretisierung fur anisotrope Diffusion, die optimale Filter verwendet, wird eingefuhrt und mit bekannten Schemata verglichen. Sie stellt sich gegenuber einer neuartigen analytischen Losung koharenzverstarkender Diffusion als 1.5 bis 2.5 Grosenordnungen genauer heraus als das beste Vergleichsverfahren und ubertrifft dieses visuell erheblich bei einer Rekonstruktionsaufgabe. Wegen der erhohten Stabilitat des Verfahrens bezuglich groser Zeitschrittweiten, ist es 3-4 mal schneller als andere explizite Schemata.
Inhibitory effect of immature plum on PMA-induced MMP-9 expression in human hepatocellular carcinoma

The goal of this study was to evaluate the anticancer effect of Prunus salicina Lindl. cv. Soldam at three maturity stages (immature, midmature and mature). In search for anticancer effects of immature plum extract (IPE), we have found its antimigrative property in (phorbol 12-myristate 13-acetate) PMA-induced HepG2 cells, and this effect is associated with inhibition of MMP-9 activity. IPE appeared to have a strong inhibitory effect on the PMA-induced MMP-9 secretion through suppression of the transcriptional activity of the MMP-9 gene independently of the TIMP gene in HepG2 cells. PMA induced the translocation of c-jun and p65 to the nucleus; however, IPE inhibited their nuclear translocations induced by PMA in HepG2 cells. These results clearly indicate that IPE suppresses both AP-1- and NF-κB-mediated MMP-9 gene transcriptional activity through inhibiting the nuclear translocations of AP-1 and NF-κB. These findings suggest that AP-1 and NF-κB activations through the ERK, p38 MAPK and JNK pathways appears to be required for the induction of MMP-9 expression by PMA in IPE, and IPE regulates PMA-stimulated MMP-9 expression by suppressing the p38 MAPK, JNK and ERK pathways. IPE leads to a decrease in the migration potential of HepG2 cells in vitro, and this suggests that the migration inhibition is correlated well with its inhibition of MMP-9 expression.
Fifteen-Month-Old Infants Use Velocity to Predict Others ’ Action Targets

Journal Name: Frontiers in Psychology ISSN: 1664-1078 Article type: Original Research Article Received on: 30 Jan 2015 Accepted on: 16 Jul 2015 Provisional PDF published on: 16 Jul 2015 Frontiers website link: www.frontiersin. org Citation: Stapel JC, Hunnius S and Bekkering H(2015) Fifteen-Month-Old Infants Use Velocity to Predict Others’ Action Targets. Front. Psychol. 6:1092. doi:10.3389/fpsyg.2015. 01092 Copyright statement: © 2015 Stapel, Hunnius and Bekkering. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
2H transmit–receive NMR probes for magnetic field monitoring in MRI

Measuring image encoding fields in real time and applying the information in postprocessing offer improved image quality for MRI, particularly for applications that are intrinsically sensitive to gradient imperfections. For this task, a stand‐alone magnetometer system based on multiple 2H transmit–receive NMR probes has been developed. The conceptual advantages of changing to 2H NMR probes for 1H magnetic field monitoring are elucidated here, and the practical design of the probes is described. In comparison to previous 1H NMR probe‐based designs, 2H probes are perfectly decoupled from standard 1H imaging. Utilization of RF shielding or other nonoptimal decoupling schemes is therefore not needed. Probes based on 2H nuclei are also more easily miniaturized for high‐resolution imaging. This is particularly important for diffusion tensor and phase‐contrast imaging, which rely on strong motion‐sensitizing gradients. The presented 2H NMR probes have been shown to fulfill the requirements for accurate 1H imaging down to image resolutions of 0.2 mm. Using susceptibility matching techniques, the probe's B0 inhomogeneity‐induced signal dephasing is reduced and monitoring periods beyond 200 msec are achieved. The benefit of real time magnetic field monitoring is highlighted for phase‐contrast and non‐Cartesian multishot imaging. Magn Reson Med, 2011. © 2010 Wiley‐Liss, Inc.
Human leukocyte antigens in Indian patients with chronic myeloid leukemia

In chronic myeloid leukemia (CML), experimental studies using synthetic peptides identical to the bcr-abl fusion region have revealed the capability of specific peptides to bind to human leukocyte antigen (HLA) class I molecules (HLA-A2, A3, A11, B8) and class II molecules (HLA-DR1, DR2, DR3, DR4 and DR11). Individuals expressing HLA-A3, B8 or DR4 have a diminished risk for the development of CML in Caucasian populations. A statistically significant increase in the frequency of Cw3 and Cw4 antigens in Caucasians and European CML patients has been reported. However, HLA associations in CML have not been reported in India. In lieu of the allelic diversity of HLA in the Indian population, the present study assessed the possibility of an association of HLA molecules in Indian patients with CML. HLA A, B, C and DRB1 antigen associations in 180 clinically diagnosed Indian CML patients (aged 17 – 54 years) were analysed and compared with age-matched (n = 100) healthy individuals from the same ethnic background. In the HLA class I antigen distribution, a significant decrease was observed in HLA-A11 (25.6% versus 39%; P = 0.027, odds ratio (OR) = 0.54, 95% confidence interval (CI) = 0.31 – 0.94) and HLA-Cw6 (7.8% versus 20%; P = 0.005, OR = 0.34, 95% CI = 0.15 – 0.74). Among the DRB1 alleles, HLA-DRB1*13 (7.8% versus 17%; P = 0.031, OR = 0.41, 95% CI = 0.18 – 0.93) was decreased in CML patients. However, the differences for HLA-A11 (Pc = 0.351) and DRB1*13 (Pc = 0.403) did not remain significant after the application of a correction factor for the P-value. These results suggest that the development of CML is apparently associated with HLA phenotypes specific to each population and indicate that expression of HLA-Cw6 may result in a protective effect on CML acquisition in the Indian population.
Mitigation of AO spurious modes in AlN MEMS resonators with SiO2 addendums

This paper presents an AO spurious mode mitigation technique for Aluminum Nitride (AlN) laterally vibrating resonators (LVRs). The technique attaches two identical SiO2 addendums to the lateral edges of the suspended AlN resonator body to shift the asymmetrical (AO) spurious modes away from the intended SO mode vibration. The AlN resonators with SiO2 addendums have been investigated theoretically with finite element analyses (FEAs) and validated experimentally. The measured response of the fabricated devices has shown successful mitigation of AO spurious mode without the compromise of electromechanical coupling, kt2, and quality factor Q.
Operational design on high-speed semiconductor optical amplifier with assist light for application to wavelength converters using cross-phase modulation

Using the newly developed time-dependent transfer matrix method with nonlinear effects, we analyzed the characteristics of cross-phase modulation (XPM), cross-gain modulation and gain recovery time of a semiconductor optical amplifier (SOA) with an assist light injection, which is introduced to speed up the gain recovery of the SOA. Particularly for the application to high-speed wavelength converters using XPM with an interferometer structure where /spl pi/-phase change is required, various parameters such as SOA lengths, wavelengths and powers of injected lights, and their propagation directions are designed via numerical simulation. Discussions concerning the conditions of an SOA structure and the parameters of injected lights for high-speed operation are described to show the potential of fast gain recovery with a response time as low as 25 ps.
The WSMO-PA Service Editor

Semantic Web Service (SWS) editors did not support until now the expression of domain specific semantics. On the other hand, the adoption of SWSs in different domains, i.e. eGovernment, eBusiness, has created the need for enhancing SWS descriptions with domain specific semantics. Therefore, models and tools that allow this integration have to be developed. The WSMO-PA Service Editor is an effort made towards this direction. It provides a friendly user interface which facilitates the creation of semantically-enhanced descriptions for Public Administration (PA) services. To do so, the WSMO-PA Service Editor combines the GEA PA Service Model, the WSMO Framework and the WSMO-PA specification.
Comparing population level sexual selection in a species with alternative reproductive tactics

The description of a species’ mating patterns is often based on observations from a single exemplar population; however, environmental variation can lead to variation in mating patterns and to differences in the strength of sexual selection among populations. In this study, we explored how resource distribution across a species’ range affects competition and the strength of sexual selection in a northern and southern population of plainfin midshipman (Porichthys notatus), a species with 2 male reproductive tactics. Male plainfin midshipman can be guarders that compete for nest sites and court females, or sneakers that attempt to steal fertilizations from the guarder males during spawning. Males from the north population grow larger, suggesting that there might be more competition among males in the north. However, we found that the variance in body size and in nest availability were similar between populations, suggesting instead a similar degree of male-male competition. We found no significant population differences in reproductive success (north: 517±50 eggs/nest ± SE; south: 412±68 eggs/nest ± SE), paternity (north: 52%; south: 58% for the guarding male), or tactic frequencies (north: 88% guarders; south: 91% guarders). There was a marginally steeper Bateman gradient in the south population but no difference at 8 other measures of the strength of sexual selection between the 2 populations. Thus, despite a wide geographic distance, our results show remarkable conservation of mating patterns between the north and south populations of this benthic toadfish.
The box a domain of high mobility group box‐1 protein as an efficient siRNA carrier with anti‐inflammatory effects

High mobility group box‐1 (HMGB‐1) is a DNA binding nuclear protein and pro‐inflammatory cytokine. The box A domain of HMGB‐1 (rHMGB‐1A) exerts an anti‐inflammatory effect, inhibiting wild‐type HMGB‐1 (wtHMGB‐1). In this study, HMGB‐1A was evaluated as an siRNA carrier with anti‐inflammatory effects. HMGB‐1A was expressed and purified by consecutive nickel chelate chromatography, cationic exchange chromatography, and polymixin B chromatography. Purified rHMGB‐1A demonstrated an anti‐inflammatory effect, reducing tumor necrosis factor‐α (TNF‐α) in wtHMGB‐1 or lipopolysaccharide (LPS) activated macrophages. In gel retardation assay, rHMGB‐1A formed a stable complex with siRNA at or above a 1:2 weight ratio (siRNA:rHMGB‐1A). A heparin competition assay showed that an siRNA/rHMGB‐1A complex released siRNA more easily than an siRNA/polyethylenimine (PEI, 25 kDa) complex. Luciferase siRNA/rHMGB‐1A reduced firefly luciferase expression at a similar level as luciferase siRNA/PEI complex. Furthermore, TNF‐α siRNA/rHMGB‐1A synergistically reduced TNF‐α expression in LPS activated macrophages. Therefore, rHMGB‐1A may be useful as an siRNA carrier with anti‐inflammatory effects in siRNA therapy for various inflammatory diseases. J. Cell. Biochem. 113: 122–131, 2012. © 2011 Wiley Periodicals, Inc.
Correlation of VEGF and Angiopoietin Expression with Disruption of Blood–Brain Barrier and Angiogenesis after Focal Cerebral Ischemia

In an effort to elucidate the molecular mechanisms underlying cerebral vascular alteration after stroke, the authors measured the spatial and temporal profiles of blood–brain barrier (BBB) leakage, angiogenesis, vascular endothelial growth factor (VEGF), associated receptors, and angiopoietins and receptors after embolic stroke in the rat. Two to four hours after onset of ischemia, VEGF mRNA increased, whereas angiopoietin 1 (Ang 1) mRNA decreased. Three-dimensional immunofluorescent analysis revealed spatial coincidence between increases of VEGF immunoreactivity and BBB leakage in the ischemic core. Two to 28 days after the onset of stroke, increased expression of VEGF/VEGF receptors and Ang/Tie2 was detected at the boundary of the ischemic lesion. Concurrently, enlarged and thin-walled vessels were detected at the boundary of the ischemic lesion, and these vessels developed into smaller vessels via sprouting and intussusception. Three-dimensional quantitative analysis of cerebral vessels at the boundary zone 14 days after ischemia revealed a significant (P < 0.05) increase in numbers of vessels (n = 365) compared with numbers (n = 66) in the homologous tissue of the contralateral hemisphere. Furthermore, capillaries in the penumbra had a significantly smaller diameter (4.8 ± 2.0 μm) than capillaries (5.4 ± 1.5 μm) in the homologous regions of the contralateral hemisphere. Together, these data suggest that acute alteration of VEGF and Ang 1 in the ischemic core may mediate BBB leakage, whereas upregulation of VEGF/VEGF receptors and Ang/Tie2 at the boundary zone may regulate neovascularization in ischemic brain.
Identification and Characterization of the Nitrobenzene Catabolic Plasmids pNB1 and pNB2 in Pseudomonas putida HS12

ABSTRACT Pseudomonas putida HS12, which is able to grow on nitrobenzene, was found to carry two plasmids, pNB1 and pNB2. The activity assay experiments of wild-type HS12(pNB1 and pNB2), a spontaneous mutant HS121(pNB2), and a cured derivative HS124(pNB1) demonstrated that the catabolic genes coding for the nitrobenzene-degrading enzymes, designated nbz, are located on two plasmids, pNB1 and pNB2. The genes nbzA,nbzC, nbzD, and nbzE, encoding nitrobenzene nitroreductase, 2-aminophenol 1,6-dioxygenase, 2-aminomuconic 6-semialdehyde dehydrogenase, and 2-aminomuconate deaminase, respectively, are located on pNB1 (59.1 kb). Meanwhile, thenbzB gene encoding hydroxylaminobenzene mutase, a second-step enzyme in the nitrobenzene catabolic pathway, was found in pNB2 (43.8 kb). Physical mapping, cloning, and functional analysis of the two plasmids and their subclones in Escherichia colistrains revealed in more detail the genetic organization of the catabolic plasmids pNB1 and pNB2. The genes nbzA andnbzB are located on the 1.1-kbSmaI-SnaBI fragment of pNB1 and the 1.0-kbSspI-SphI fragment of pNB2, respectively, and their expressions were not tightly regulated. On the other hand, the genes nbzC, nbzD, and nbzE, involved in the ring cleavage pathway of 2-aminophenol, are localized on the 6.6-kb SnaBI-SmaI fragment of pNB1 and clustered in the order nbzC-nbzD-nbzE as an operon. ThenbzCDE genes, which are transcribed in the opposite direction of the nbzA gene, are coordinately regulated by both nitrobenzene and a positive transcriptional regulator that seems to be encoded on pNB2.
SocICoAP: Social Interaction with Supplementary Sensors and Actuators through CoAP in Smartphones

In the Internet of Things (IoT) a worldwide network of sensors and actuators transmit data and actuate over the Internet. Nevertheless, the deployment of sensors and actuators usually requires tools to program and configure them before they can work, and not everyone has such access. Current smartphones are provided with a large set of sensors and actuators that can be incorporated in the IoT. With the aim of achieving seamless integration, this paper presents SocICoAP, a system that enables the sharing of sensors and actuators present in smartphones and installing custom ones at run-time in microcontrollers. In this way smartphones are integrated into the IoT, not only a sensor providing data from its built-in sensors but also as a gateway for nearby deployed sensors. Furthermore, the sensor data can also be globally shared and analysed through a cloud computing integration.
Position-based power planning for fair resource allocation in LTE-A

This paper considers the use of predefined frequency-domain power profiles in downlink LTE-A aiming at making interference predictable across the Physical Resource Blocks, to be combined with fair resource allocation. In particular, the power profile structure is defined depending on the position of the users and fairness-oriented scheduling strategies are considered. Evaluations of the throughput and fairness achieved in the system depending on different scheduling algorithms are reported, as well as a comparison with scheduling strategies implementing power control techniques at similar complexity. Results show that, when resource allocation is SINR-based and focuses on cell-edge users, the highest sum rate and average per user rate is achieved without significant loss from the optimum fairness.
Gemmatirosa kalamazoonesis gen. nov., sp. nov., a member of the rarely-cultivated bacterial phylum Gemmatimonadetes.

Strain KBS708 was isolated from organically managed agricultural soil supporting a wheat-corn-soybean rotation at the Long Term Eco-logical Research Site at Kellogg Biological Station in Hickory Corners, Michigan, USA. This site is located in the Kalamazoo soil series, from which the proposed bacterial species name is derived. Soil parameters were measured as previously described (DeBruyn et al., 2011): soils were pH 5.6 with 0.12% N, 1.3% C, and 2.0 ppm Mehlich3-extractable PO
Coordinate Regulation of the Suf and Isc Fe-S Cluster Biogenesis Pathways by IscR Is Essential for Viability of Escherichia coli

ABSTRACT Fe-S cluster biogenesis is essential for the viability of most organisms. In Escherichia coli, this process requires either the housekeeping Isc or the stress-induced Suf pathway. The global regulator IscR coordinates cluster synthesis by repressing transcription of the isc operon by [2Fe-2S]-IscR and activating expression of the suf operon. We show that either [2Fe-2S]-IscR or apo-IscR can activate suf, making expression sensitive to mainly IscR levels and not the cluster state, unlike isc expression. We also demonstrate that in the absence of isc, IscR-dependent suf activation is essential since strains lacking both the Isc pathway and IscR were not viable unless Suf was expressed ectopically. Similarly, removal of the IscR binding site in the sufA promoter also led to a requirement for isc. Furthermore, suf expression was increased in a Δisc mutant, presumably due to increased IscR levels in this mutant. This was surprising because the iron-dependent repressor Fur, whose higher-affinity binding at the sufA promoter should occlude IscR binding, showed only partial repression. In addition, Fur derepression was not sufficient for viability in the absence of IscR and the Isc pathway, highlighting the importance of direct IscR activation. Finally, a mutant lacking Fur and the Isc pathway increased suf expression to the highest observed levels and nearly restored [2Fe-2S]-IscR activity, providing a mechanism for regulating IscR activity under stress conditions. Together, these findings have enhanced our understanding of the homeostatic mechanism by which cells use one regulator, IscR, to differentially control Fe-S cluster biogenesis pathways to ensure viability.
Epidemiology of Weaning Outcome according to a New Definition. The WIND Study

Rationale: The weaning process concerns all patients receiving mechanical ventilation. A previous classification into simple, prolonged, and difficult weaning ignored weaning failure and presupposed the use of spontaneous breathing trials. Objectives: To describe the weaning process, defined as starting with any attempt at separation from mechanical ventilation and its prognosis, according to a new operational classification working for all patients under ventilation. Methods: This was a multinational prospective multicenter observational study over 3 months of all patients receiving mechanical ventilation in 36 intensive care units, with daily collection of ventilation and weaning modalities. Pragmatic definitions of separation attempt and weaning success allowed us to allocate patients in four groups. Measurements and Main Results: A total of 2,729 patients were enrolled. Although half of them could not be classified using the previous definition, 99% entered the groups on the basis of our new definition as follows: 24% never started a weaning process, 57% had a weaning process of less than 24 hours (group 1), 10% had a difficult weaning of more than 1 day and less than 1 week (group 2), and 9% had a prolonged weaning duration of 1 week or more (group 3). Duration of ventilation, intensive care unit stay, and mortality (6, 17, and 29% for the three groups, respectively) all significantly increased from one group to the next. The unadjusted risk of dying was 19% after the first separation attempt and increased to 37% after 10 days. Conclusions: A new classification allows us to categorize all weaning situations. Every additional day without a weaning success after the first separation attempt increases the risk of dying.
Tratamiento de la tuberculosis resistente a múltiples drogas

Se hace una revision de la situacion actual de la tuberculosis a multiples drogas en el mundo, los mecanismos biologicos que producen la misma, su epidemiologia que pone de manifiesto las grandes diferencias existentes entre las distintas regiones del mundo en cuanto al numero de casos y su atencion, asi como las bases del tratamiento de tan dificil problema con las llamadas drogas de segunda linea. Se mencionan algunos nuevos medicamentos que traen ciertas esperanzas en la mejoria del pronostico de dicha enfermedad.