Miracle-dz/UniFAR-FTUs huggingface dataset:
Mission-level performance verification approach for the Euclid space mission

ESA's Dark Energy Mission Euclid will map the 3D matter distribution in our Universe using two Dark Energy probes: Weak Lensing (WL) and Galaxy Clustering (GC). The extreme accuracy required for both probes can only be achieved by observing from space in order to limit all observational biases in the measurements of the tracer galaxies. Weak Lensing requires an extremely high precision measurement of galaxy shapes realised with the Visual Imager (VIS) as well as photometric redshift measurements using near-infrared photometry provided by the Near Infrared Spectrometer Photometer (NISP). Galaxy Clustering requires accurate redshifts (Δz/(z+1)<0.1%) of galaxies to be obtained by the NISP Spectrometer. Performance requirements on spacecraft, telescope assembly, scientific instruments and the ground data-processing have been carefully budgeted to meet the demanding top level science requirements. As part of the mission development, the verification of scientific performances needs mission-level end-to-end analyses in which the Euclid systems are modeled from as-designed to final as-built flight configurations. We present the plan to carry out end-to-end analysis coordinated by the ESA project team with the collaboration of the Euclid Consortium. The plan includes the definition of key performance parameters and their process of verification, the input and output identification and the management of applicable mission configurations in the parameter database.
Amino acid sequences containing half-cystine residues in ovalbumin.

Ovalbumin is known to have six half-cystine residues with four thiol groups and one disulfide bond. Peptides containing the six half-cystine residues labelled with [2acid were isolated from pepsin digests of reduced and S-carboxyn1ethylated ovalbumin by gel filtration, paper ionophoresis and paper chromatography. These peptides were analysed for amino acids and sequenced by the dansyl-Edman procedure. Cysteic acid peptides, selectively recovered from enzyme digests of performic acid-oxidized ovalbumin, were used to confirm some sequences. The amino acid sequences around the two half-cystine residues involved in the disulfide bond were determined on cysteic acid peptides. These were derived from the disulfide-containing peptide of S-carboxymethylated ovalbumin after pepsin digestion and fractionation by gel filtration, ionophoresis at pH 1·8, performic acid oxidation and another ionophoresis by the diagonal technique. The disulfide-bond involves the sequences (A) -Asp-Lys-Leu-Pro-Gly-Phe-Gly-Asp-SerP-Ile-Glu-Ala-Gln-Cys-Gly-Thr-Ser-Val-Asxand (B) -Pro-Glu-Tyr-Leu-Gln-Cys-Val-Lys-Glu-. The thiol-containing sequences in ovalbumin are (C) -Tyr-Cys-Pro-Ile-Ala-Ile-Met-, (D) -Ala-Ala-Ser-Met-Glu-Phe-Cys-Phe-Asp-Val-Phe-Lys-, (E) -Phe-Gly-Arg-Cys-Val-Ser-Pro-, (F) -Phe-Cys-Ile-Lys-His-Ile-Ala-Thr-.
LIMSoft: automated tool for design and test integration of analog circuits

Integrating design and test presents a good challenge in today's analog circuit manufacturing process. Designs should be made according to the sensitivity of the output to all the components. Furthermore, sensitivity can be used to observe component deviation (soft faults) and hard faults from the output. This paper presents an automated sensitivity analysis tool, called LIMSoft, which offers the possibility of sensitivity computation and analysis in order to design fault-resistant circuits and generate test vectors for both soft and hard faults. Some applications for integrating test and design are also presented.
Improving user complaint management system and satisfaction level via reader-friendly linguistic features

This survey was done due to high non-satisfaction level of a usage system, known as e-Aduan, an electronic system used to generate electrical, mechanical, telecommunication, civil, landscape, infrastructure or facilities management complaint from user. e-Aduan is subscribed and handled by Universiti Teknologi Mara (UiTM), for all developers of 7 Private Fund Institution (PFI) Campuses located throughout Malaysia which mostly are one year established. This exploratory research found 67% of the total 168 respondents have never used e-Aduan. Some of the reasons raised were because users were not familiar with the service, the system was not user friendly and it was difficult to access. This survey also revealed 55% users of e-Aduan were dissatisfied in using it. Thus, this study recommended restructuring the Service Operating Procedure (SOP) of this system besides improving the system via reader-friendly linguistic features as an approach to enhance the quality of the service as well as customer satisfaction level when using the system. Suggestion for future research includes the participation of respondents from all UiTM PFI Campuses.
Mso1 Is a Novel Component of the Yeast Exocytic SNARE Complex*

The yeast exocytic SNARE complex consists of one molecule each of the Sso1/2 target SNAREs, Snc1/2 vesicular SNAREs, and the Sec9 target SNARE, which form a fusion complex that is conserved in evolution. Another protein, Sec1, binds to the SNARE complex to facilitate assembly. We show that Mso1, a Sec1-interacting protein, also binds to the SNARE complex and plays a role in mediating Sec1 functions. Like Sec1, Mso1 bound to SNAREs in cells containing SNARE complexes (i.e. wild-type, sec1-1, and sec18-1 cells), but not in cells in which complex formation is inhibited (i.e. sec4-8 cells). Nevertheless, Mso1 remained associated with Sec1 even in sec4-8 cells, indicating that they act as a pair. Mso1 localized primarily to the plasma membrane of the bud when SNARE complex formation was not impaired but was mostly in the cytoplasm when assembly was prevented. Genetic studies suggest that Mso1 enhances Sec1 function while attenuating Sec4 GTPase function. This dual action may impart temporal regulation between Sec4 turnoff and Sec1-mediated SNARE assembly. Notably, a small region at the C terminus of Mso1 is conserved in the mammalian Munc13/Mint proteins and is necessary for proper membrane localization. Overexpression of Mso1 lacking this domain (Mso1-(1–193)) inhibited the growth of cells bearing an attenuated Sec4 GTPase. These results suggest that Mso1 is a component of the exocytic SNARE complex and a possible ortholog of the Munc13/Mint proteins.
Comparative toxicity of eight metals on freshwater fish

Two freshwater fish, Rasbora sumatrana (Cyprinidae) and Poecilia reticulata (guppy; Poeciliidae), were exposed to a range of eight heavy metals (copper (Cu), cadmium (Cd), zinc (Zn), lead (Pb), nickel (Ni), iron (Fe), aluminium (Al), and manganese (Mn)) at varied concentrations for 96 h in the laboratory. Mortality was assessed and median lethal concentrations (LC50) were calculated. It was observed that the LC50 values increased with a decrease in mean exposure times, for all metals and for both fish types. The 96-h LC50 values for Cu, Cd, Zn, Pb, Ni, Fe, Al, and Mn were 0.006, 0.10, 0.46, 0.63, 0.83, 1.71, 1.53, and 5.71 mg/L for R. sumatrana and 0.038, 0.17, 1.06, 1.99, 15.62, 1.46, 6.76, and 23.91 mg/L for P. reticulata, respectively. The metal toxicity trend for R. sumatrana and P. reticulata from most to least toxic was Cu > Cd > Zn > Pb > Ni > Al > Fe > Mn and Cu > Cd > Zn > Fe > Pb > Al > Ni > Mn, respectively. Results indicated that Cu was the most toxic metal on both fish, and R. sumatrana was more sensitive than P. reticulata to all the eight metals.
Exploring the Relationships Between Just-In-Time Technique and Manufacturing Performance: Empirical Evidence From Selected Nigerian Firms

This study explores the relationship between just-in-time technique and manufacturing performance of some selected Nigerian companies. Just-in time was considered to be an overall organisational phenomenon. Data were obtained through a structured questionnaire from a sample size of 300 knowledgeable employees to test the developed model and formulated hypotheses that cover both just-intime and the supporting infrastructures. Bivariate correlation analysis was used to test the three hypotheses. The results showed that: (1) there was a significant relationship between total quality management (supporting infrastructure) and just-in-time practices; (2) Human resources management (supporting infrastructure) was positively related to just-in-time practices; (3) there was a positive significant relationship between Just-in-time practices and manufacturing performance. These results demonstrate that justin-time practices can be successfully implemented if certain supporting infrastructures are provided, and also support the notion that just-in-time should be practiced at all levels and departments of the organisation, rather than viewing it strictly for shop floor workers.
Osseous response on linear and cyclic RGD-peptides immobilized on titanium surfaces in vitro and in vivo.

Biomimetic surface modifications of titanium (Ti) implants using the Arg-Gly-Asp-sequence (RGD) are promising to accelerate bone healing in cases of medical implants. Therefore, we compared the impact of linear and cyclic RGD (l- and c-RGD) covalently coupled onto Ti surfaces on the osseous response in vitro and in vivo. In vitro, osteoblasts' behavior on different surfaces (unmodified, amino-silanized [APTES], l- and c-RGD) was analysed regarding adhesion (fluorescence microscopy), proliferation (resazurin stain) and differentiation (reverse transcription polymerase chain reaction on alkaline phosphatase and osteocalcin). In vivo, osteosynthesis screws (unmodified n = 8, l-RGD n = 8, c-RGD n = 8) were inserted into the proximal tibiae of 12 rabbits and evaluated for bone growth parameters (bone implant contact [%] and vertical bone apposition [VBA;%]) at 3 and 6 weeks. In vitro, c- as well as l-RGD surfaces stimulated osteoblasts' adherence, proliferation and differentiation in a similar manner, with only subtle evidence of superiority of the c-RGD modifications. In vivo, c-RGD-modifications led to a significantly increased VBA after 3 and 6 weeks. Thus, coating with c-RGD appears to play an important role influencing osteoblasts' behaviour in vitro but especially in vivo. These findings can be applied prospectively to implantable biomaterials with hypothetically improved survival and success rates. © 2017 Wiley Periodicals Inc. J Biomed Mater Res Part A: 106A: 419-427, 2018.
Compact Implementation of Skein-256 Hash Function on FPGA

In this paper we have presented a low-area design of Skein-256 hash function on Xilinx Virtex-5 FPGA. Skein is one of the 5 finalists of SHA-3 competition. Our implementation is utilizing only 527 slices and shows a throughput of 1.295 Gbps. Comparing our results with the previous published FPGA implementations of Skein-256, our design reports the best TPS of 2.457. High value of TPS shows the efficiency of our design.
Enhanced Performance of a Temperature-Compensated Submeter Spatial Resolution Distributed Strain Sensor

We demonstrate a scheme which allows for temperature-corrected distributed strain measurements with improved spatial and strain resolutions and reduced data collection time. The technique utilizes the combination of frequency-based Brillouin optical correlation domain analysis with Brillouin intensity measurements for a fully temperature-compensated strain sensor with a strain resolution of 56 με and spatial and temperature resolutions of 10 cms and 0.95 °C.
A random obstacle‐based mobility model for delay‐tolerant networking

When evaluating a new protocol in the network, it is important to use a realistic mobility model to reflect the actual performance of a mobile system. Only the realistic mobility model can better mimic the reality and get more reliable data. However, most existing mobile models of delay‐tolerant networking (DTN) move randomly or on the road according to some rules under the environment without obstacles. These mobile models, without considering the impact of obstacles on the node, do not accord with the fact. To address this problem, we propose a random obstacle‐based mobility model (ROM) aimed at better simulating the real trajectory of a human for DTN in the presence of obstacles. In this model, we can place arbitrary‐shape obstacles in accordance with any actual scene, as well as considering the influence of obstacles on the signal. The mobile path of a node calculated by this node is the shortest path to the destination avoiding certain types of obstacles. In addition, the propagation model contains the attenuation of the signal due to the existence of obstacles. As a result, we have developed a complete obstacle mobility model which is more suitable for studying the performance of the network. We augment the ‘opportunistic network environment’ (ONE) simulator of DTN with required extensions and show that characteristics of the DTN are very different using the new model than it is under models that ONE currently provides. Copyright © 2011 John Wiley & Sons, Ltd.
Hypervisor based Memory Introspection: Challenges, Problems and Limitations

Hypervisor-based memory introspection is a well-known topic, in both academia and the industry. It is accepted that this technique brings great advantages from a security perspective, but it is known, as well, that this comes at greater implementation complexity and performance penalty. While the most obvious challenges, such as the semantic gap, have been greatly discussed in the literature, we aim to elaborate on the engineering and implementation challenges encountered while developing a hypervisor-based memory introspection solution and to offer theoretical and practical solutions for them.
Remyelination occurs as extensively but more slowly in old rats compared to young rats following gliotoxin‐induced CNS demyelination

Age is one of the many factors that influence remyelination following CNS demyelination, although it is not clear whether it is the extent or rate of remyelination that is affected. To resolve this issue we have compared remyelination in young and old adult rat CNS following gliotoxin‐induced demyelination. Remyelination of areas of ethidium bromide‐induced demyelination in the caudal cerebellar peduncle reached completion by 4 weeks in young adult rats (2 months) but was not complete until 9 weeks in old adult rats (9–12 months). We have also shown that remyelination of lysolecithin‐induced demyelination in the spinal white matter of old adult rats (18 months) can be extensive, with longer survival times (8 weeks) than have previously been examined. Thus, it is the rate rather than the extent of remyelination that changes in the ageing CNS. These results have important implications for understanding the mechanisms of remyelination, indicating that remyelination need not occur rapidly for it to be extensive. The capacity for the process of remyelination to continue over many weeks must also be borne in mind when assessing remyelination‐enhancement strategies either by transplantation or promotion of endogenous mechanisms. GLIA 28:77–83, 1999. © 1999 Wiley‐Liss, Inc.
ONTOLOGY-BASED HEURISTIC ALGORITHM FOR TEXT CLASSIFICATION IN OIL INDUSTRY APPLICATION

Today, with the advances of new technologies, accidents, incidents and occupational health records are stored in diverse repositories. The amount of information of HSE that is daily generated has become increasingly huge. Most of this information is stored as unstructured data. The challenge of unstructured data is a top priority for industries that are looking for ways to search, sort, analyze and extract knowledge from masses of data. In this paper we provide with a solution to oil and gas industry for accident investigation using information extraction techniques. The main objective is to propose and evaluate information extraction techniques in occupational health control process, particularly, for automatic detection of accidents from unstructured texts. Our proposal divides the problem in subtasks such as text analysis, recognition and classification of failed occupational health control, resolving accidents.
Thatcher and the Cheshire Cat: Context and the Processing of Facial Features

As has been noted before, a face made gruesome by the inversion of its mouth will not be so perceived when the entire construction is inverted. Results are presented which suggest that this is because (a) the mouth and eye features are evaluated individually (although each feature may influence the evaluation of the other) and (b) the mouth, whether normal or inverted, tends to have its uppermost part assigned as ‘top’, providing for either a pleasant smiling-mouth expression or a gruesome ‘biting-intention’ expression. However, the gruesomeness of an inverted mouth is attenuated when eyes are shown below it (producing an inverted smiling face) which suggests that the location of other facial features can also influence the assignments of ‘top’.
Participation profiles in domestic life and peer relations as experienced by adolescents with and without impairments and long-term health conditions

ABSTRACT Purpose: To investigate how individual and environmental factors relate to self-reported participation profiles in adolescents with and without impairments or long-term health conditions. Methods: A person-oriented approach (hierarchical cluster analysis) was used to identify cluster groups of individuals sharing participation patterns in the outcome variables frequency perceived importance in domestic life and peer relations. Cluster groups were compared using one-way analysis of variance (ANOVA). Results: A nine-cluster solution was chosen. All clusters included adolescents with impairment and long-term health conditions. Perceived importance of peer relations was more important than frequent attendance in domestic-life activities. Frequency of participation in dialogues and family interaction patterns seemed to affect the participation profiles more than factors related to body functions. Conclusion: Type of impairment or long-term health condition is a weaker determinant of membership in clusters depicting frequency and perceived importance in domestic life or peer relations than dialogue and family environment.
Lack of pharmacokinetic interaction between valproic acid and a traditional Chinese medicine, Paeoniae Radix, in healthy volunteers

Background and objective: In addition to the standard antiepileptic drugs, traditional Chinese medicines (TCMs) are used for the treatment of epilepsy in oriental countries. The interactions between antiepileptic drugs and TCMs represent a potential problem in clinical application. Because valproic acid (VPA), one of the most widely prescribed antiepileptic drugs, may be administered concomitantly with Paeoniae Radix (PR), one of the famous TCMs, in some epileptic patients, the present study was conducted to evaluate the influences of PR on the pharmacokinetics of VPA.
CAMEL ANALYSIS OF NBFCs IN TAMILNADU

Financial intermediation is a crucial function of Banks, Non Banking financial companies (NBFCs) and Development Financial Institutions (DFIs) the post reform period in India is characterized by phenomenal growth of NBFCs complementing the role of banks in mobilizing funds and making it available for investment purposes. During the last decade NBFCs have undergone wide volatility and change as an industry and have been witnessing considerable business upheaval over the last decade because of market dynamics, public sentiments and regulatory environment. To evaluate the soundness of NBFCs in Tamil Nadu over a decade, the authors made an attempt of CAMEL criteria for analysis of selected Companies. For this purpose, out of 36 NBFCs in Tamil Nadu 4 Government Companies, 13 Small Companies and 13 Small Companies and another 13 Top Companies were selected as sample respondents on the basis of multi-stage random sampling, To evaluate soundness of each NBFCs through Capital Adequacy, Asset Quality, Management quality, Earnings and Liquidity, Based on findings the suggestions were offered to overcome the difficulties face by selected NBFCs in their development.
Factors Determining the Clinical Utility of Serial Measurements of Antineutrophil Cytoplasmic Antibodies Targeting Proteinase 3

Relapse following remission is common in antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV), particularly with ANCAs directed at proteinase 3 (PR3). This study was undertaken to evaluate the association of an increase in PR3‐ANCA level with subsequent relapse.
Coupling Among Energy Failure, Loss of Ion Homeostasis, and Phospholipase A2 and C Activation During Ischemia

Abstract— The objective of the present experiments was to correlate changes in cellular energy metabolism, dissipative ion fluxes, and lipolysis during the first 90 s of ischemia and, hence, to establish whether phospholipase A2or phospholipase C is responsible for the early accumulation of phospholipid hydrolysis products. Ischemia was induced for 15–90 s in rats, extracellular K+ (K+e) was recorded, and neocortex was frozen in situ for measurements of labile tissue metabolites, free fatty acids, and diacylglycerides. Ischemia of 15‐and 30‐s duration gave rise to a decrease in phosphocreatine concentration and a decline in the ATP/free ADP ratio. Although these changes were accompanied by an activation of K+ conductances, there were no changes in free fatty acids until after 60s, when free arachidonic acid accumulated. An increase in other free fatty acids and in total diacylglyceride content did not occur until after anoxic depolarization. The results demonstrate that the early functional changes, such as activation of K+ conductances, are unrelated to changes in lipids or lipid mediators. They furthermore suggest that the initial lipolysis occurs via both phospholipase A2 and phospholipase C, which are activated when membrane depolarization leads to influx of calcium into cells.
Predictors of College Students' Alcohol Consumption: Implications for Student Education

Abstract Understanding why young adults consume alcohol the way they do can lead to more effective educational programming for promotion of students' personal health and safety. The authors examined the predictive role of expectations about alcohol, perceived peer norms of consumption, awareness of rules, and individual self-efficacy in conjunction with demographic variables for male and female college students' weekly alcohol consumption. The sample of 4,960 students analyzed here is 10 to 20 times larger and more nationally representative than the samples used in similar studies. The authors used a general linear model; 41% of the men's variance and 33% of the women's variance in self-reported weekly alcohol consumption were explained by the set of predictors. In descending order of variance accounted for in male and female students' self-reported weekly alcohol consumption, perceived gender-specific norms of consumption, expectations about the effects of alcohol, and the importance of drinking in high school were significant predictors for both men and women. The salience of psychological variables for young adults' consumption of alcohol underscores the importance of recognizing individual predictors of behavior in the broader ecological context in which those behaviors are performed.