Miracle-dz/UniFAR-FTUs huggingface dataset:
What positive encounters with healthcare and social insurance staff promotes ability to return to work of long-term sickness absentees?

Aims: Previous studies suggest that positive encounters with healthcare and social insurance staff may be important in promoting return to work among long-term sickness absentees. This study aimed to identify more specifically what positive encounters are important for promoting ability to return to work. Methods: A questionnaire about different types of encounters was sent to 10,042 people in Sweden on sick leave for 6–8 months (58% responded). For each positive encounter, we estimated the marginal probability difference (PD) of return to work, adjusting for age, sex, education, sick-leave diagnosis, and the sum score of all other encounters. Adjusting for the other encounters is important since of the observed variables these were the strongest confounders. Results: The positive encounters with both healthcare and social insurance staff significantly associated with promoting ability to return to work after adjusting for the other positive encounters were “Believed in my work capacity” PD=16.9 (95% CI: 12.0, 21.9) and 12.0 (6.3, 17.7), respectively; “Supported my suggestions for solutions”: 9.5 (3.1, 15.9) and 11.6 (5.7, 17.4); “Was supportive and encouraging”: 10.1 (3.6, 16.7) and 7.3 (1.7, 12.8). Additionally, the encounter with healthcare staff most strongly associated with promoting return to work was “Let me take responsibility” 14.8 (7.2, 22.3); and with social security staff: “Showed that she/he liked me” 10.4 (5.4, 15.4). Conclusions: Healthcare and social security staff being supportive, encouraging, and believing in the sickness absentee’s work capacity may be very important for increasing the probability for long-term sickness absentees’ ability to return to work.
Situational Method Engineering: Fundamentals and Experiences, Proceedings of the IFIP WG 8.1 Working Conference, 12-14 September 2007, Geneva, Switzerland

Keynote Talks. - Domain-Specific Modeling: The Killer App for Method Engineering? - Method Engineering: Trends and Challenges. - Supporting Situational Method Engineering with ISO/IEC 24744 and the Work Product Pool Approach. - Fundamentals. - Multi-Grounded Action Research in Method Engineering: The MMC Case. - Situational Method Engineering. - Examining Key Notions for Method Adaptation. - Situational Method Engineering. - Method Chunks Selection by Multicriteria Techniques: an Extension of the Assembly-based Approach. - Reuse Mechanisms in Situational Method Engineering. - Developer Driven Approach to Situational Method Engineering. - Meta-modelling Approaches. - Characterizing Knowledge Intensive Tasks indicating Cognitive Requirements Scenarios in Methods for Specific Tasks. - Partial Evaluation in Meta Modeling. - Representation of Method Fragments. - Perspectives on Method Engineering. - Taxonomic Dimensions for Studying Situational Method Development. - Component-based Situational Methods. - Connecting method engineering knowledge: a community based approach. - Method Quality. - Situational Method Quality. - Complete Methods for Building Complete Applications. - Process Patterns for Agile Methodologies. - Domain Specific Methods. - Domain-specific Adaptations of Product Line Variability Modeling. - A Look at Misuse Cases for Safety Concerns. - Engineering Medical Processes to Improve Their Safety. - Process Improvement. - Software Process Improvement Based on the Method Engineering Principles. - Defining a Scope for COTS Selection Methods. - Developing a Reference Method for Game Production by Method Comparison. - Organisation Modelling. - Towards Evidence Based Splitting of Organizations. - A Formal Framework for Modeling and Analysis of Organizations. - Panel. - Modularization Constructs in Method Engineering: Towards Common Ground?
Global planning of whole-body manipulation by humanoid robot based on transition graph of object motion and contact switching

Abstract Humanoid robot has the potential to achieve various manipulation strategies such as lifting, pushing, pivoting and rolling. Deciding which strategies to apply for the object manipulation is difficult because the appropriate manipulation motion varies greatly depending on the object property. We propose the planning method of whole-body manipulation for various manipulati on strategies. In order to plan the manipulation in the global scope, we generate the graph representing all the possible object poses and operation contacts. By searching the feasible path in the graph, we plan the sequence of object states satisfying the kinematics and dynamics conditions. Finally, the robot postures for the whole-body manipulation are generated from the object states. The proposed method is efficient because the tractable object configuration is first planned in the global scope and then the complicated robot configuration is calculated. We show the effectiveness of the proposed method by planning the humanoid robot motion for various manipulation strategies automatically from the object and robot models. Graphical Abstract
Dual-composite right-left-handed transmission lines for the design of compact diplexers

In this study, the use of dual-composite right-left-handed (D-CRLH) transmission lines is proposed for the design of diplexers. The D-CRLH diplexers present advantages over conventional diplexers such as smaller size (especially in the ultra high frequency band). The design procedure and the design equations are presented in this paper. The non-linear phase response of a D-CRLH transmission line has been used to design diplexers at any arbitrary frequencies. Finally, two diplexers have been designed and manufactured: one for quite near frequencies and the other for further ones. The simulation results show good agreement with the measurements. A sensitivity analysis has been provided to show the robustness of this kind of circuits.
Relationship between organisational safety culture dimensions and crashes

Knowing about organisational safety culture in public transportation system can provide an appropriate guide to establish effective safety measures and interventions to improve safety at work. The aim of this study was investigation of association between safety culture dimensions (leadership styles and company values, usage of crashes information and prevention programmes, management commitment and safety policy, participation and control) with involved self-reported crashes. The associations were considered through Spearman correlation, Pearson chi-square test and logistic regression. The results showed an association among self-reported crashes (occurrence or non-occurrence) and factors including leadership styles and company values; management commitment and safety policy; and control. Moreover, it was found a negative correlation and an odds ratio less than one between control and self-reported crashes.
Cystic fibrosis transmembrane conductance regulator with a shortened R domain rescues the intestinal phenotype of CFTR−/− mice

Gene transfer could provide a novel therapeutic approach for cystic fibrosis (CF), and adeno-associated virus (AAV) is a promising vector. However, the packaging capacity of AAV limits inclusion of the full-length cystic fibrosis transmembrane conductance regulator (CFTR) cDNA together with other regulatory and structural elements. To overcome AAV size constraints, we recently developed a shortened CFTR missing the N-terminal portion of the R domain (residues 708–759, CFTRΔR) and found that it retained regulated anion channel activity in vitro. To test the hypothesis that CFTRΔR could correct in vivo defects, we generated CFTR−/− mice bearing a transgene with a fatty acid binding protein promoter driving expression of human CFTRΔR in the intestine (CFTR−/−;TgΔR). We found that intestinal crypts of CFTR−/−;TgΔR mice expressed CFTRΔR and the intestine appeared histologically similar to that of WT mice. Moreover, like full-length CFTR transgene, the CFTRΔR transgene produced CFTR Cl− currents and rescued the CFTR−/− intestinal phenotype. These results indicate that the N-terminal part of the CFTR R domain is dispensable for in vivo intestinal physiology. Thus, CFTRΔR may have utility for AAV-mediated gene transfer in CF.
A Finite-state Morphological Analyser for Tuvan

~This paper describes the development of free/open-source finite-state morphological transducers for Tuvan, a Turkic language spoken in and around the Tuvan Republic in Russia. The finite-state toolkit used for the work is the Helsinki Finite-State Toolkit (HFST), we use the lexc formalism for modelling the morphotactics and twol formalism for modelling morphophonological alternations. We present a novel description of the morphological combinatorics of pseudo-derivational morphemes in Tuvan. An evaluation is presented which shows that the transducer has a reasonable coverage―around 93%―on freely-available corpora of the languages, and high precision―over 99%―on a manually verified test set.
The Multi-Round Balanced Traveling Tournament Problem

Given an n-team sports league, the Traveling Tournament Problem (TTP) seeks to determine an optimal double round-robin schedule minimizing the sum total of distances traveled by the n teams as they move from city to city. In the TTP, the number of "rounds" is fixed at r = 2. In this paper, we propose the Multi-Round Balanced Traveling Tournament Problem (mb-TTP), inspired by the actual league structure of Japanese professional baseball, where n = 6 teams play 120 intra-league games over r = 8 rounds, subject to various constraints that ensure competitive balance. These additional balancing constraints enable us to reformulate the 2k-round mb-TTP as a shortest path problem on a directed graph, for all k >= 1. We apply our theoretical algorithm to the 6-team Nippon (Japanese) Professional Baseball Central League, creating a distance-optimal schedule with 57836 kilometres of total travel, a 26.8% reduction compared to the 79067 kilometres traveled by these six teams during the 2010 regular season.
Kinetics of Heterogeneous Catalytic Reactions

This book is a critical account of the principles of the kinetics of heterogeneous catalytic reactions in the light of recent developments in surface science and catalysis science.Originally published in 1984.The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These paperback editions preserve the original texts of these important books while presenting them in durable paperback editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Efficient bit allocation using new intra and inter-frame modeling for H.264/AVC

Rate control is a critical issue in H.264∕AVC video coding standard because it suffers from some shortcomings that make the bit allocation process not optimal. This leads to a video quality that may vary significantly from frame to frame. Our aim is to enhance the rate control efficiency in H.264∕AVC baseline profile by handling two of its defects: the initial quantization parameter (QP) estimation for Intra- Frames (I-Frames) and the target number of bits determination for Inter-Frames (P-Frames) encoding. First, we propose a Rate- Quantization (R-Q) model for the I-Frame constructed empirically after extensive experiments. The optimal initial QP calculation is based on both target bit-rate and I-Frame complexity. The I-Frame target bit-rate is derived from the global target bit-rate by using a new non-linear model. Secondly, we propose an enhancement of the bit allocation process by exploiting frame complexity measures. The target number of bits determination for P-Frames is adjusted by combining two temporal measures: the first is a motion ratio based on actual bits used to encode previous frames; the second measure exploits the difference between two consecutive frames and the histogram of this difference. The simulation results, carried out using the JM15.0 reference software and the JVT-O016 rate control algorithm, show that the right choice of initial QP for I-Frame and first P-Frame allows improvement of both the bit-rate and peak signal-to-noise ratio (PSNR). Finally, the Inter-Frame bit allocation process further improves the bit-rates while keeping the same PSNR improvement (up to .1.33 dB∕ . 2 dB for QCIF/CIF resolutions). Moreover, this process reduces the buffer level variation leading to a more consistent quality of reconstructed videos.
TDOA-based distance estimation for mobile beacon-assisted localization in large-scale sensor networks

In large-scale sensor network, self-locating a sensor node is important in order to monitor events occurring in surroundings. A distance to a reference point is key information to estimate location of a sensor node. In this paper, we propose TDOA-based distance estimation to improve accuracy in a distance to a reference point where a mobile beacon broadcast its absolute position. For locating asynchronous sensor nodes, we first model a set of TDOA-based measured distances to a mobile beacon moving along the linear tracks. Based on the model, distance estimation adopts Gauss-Newton method to minimize square errors in measurements. Through simulation, the proposed scheme shows that it can provide high accuracy in distance estimation compared to our previous work [4].
Manipulating Gene Expression in Projection‐Specific Neuronal Populations Using Combinatorial Viral Approaches

The mammalian brain contains tremendous structural and genetic complexity that is vital for its function. The elucidation of gene expression profiles in the brain, coupled with the development of large‐scale connectivity maps and emerging viral vector–based approaches for target‐selective gene manipulation, now allows for detailed dissection of gene‐circuit interfaces. This protocol details how to perform combinatorial viral injections to manipulate gene expression in subsets of neurons interconnecting two brain regions. This method uses stereotaxic injection of a retrograde transducing CAV2‐Cre virus into one brain region, combined with injection of a locally transducing Cre‐dependent AAV virus into another brain region. This technique is widely applicable to the genetic dissection of neural circuitry, as it enables selective expression of candidate genes, dominant‐negatives, fluorescent reporters, or genetic tools within heterogeneous populations of neurons, based upon their projection targets. Curr. Protoc. Neurosci. 65:4.35. 1‐4.35. 20. © 2013 by John Wiley & Sons, Inc.
A new trimethoprim resistance gene, dhfrX, in the In7 integron of plasmid pDGO100

A new trimethoprim resistance determinant, designated dhfrX, was identified in the In7 integron of pDGO100. The sequence of the dhfrX dihydrofolate reductase is up to 28% identical to the sequences of several known dihydrofolate reductase proteins. The dhfrX gene is adjacent to the second 3'-conserved segment of the In7 integron, but the first 77 bases of this segment are not present.
Efficient variant of algorithm fastica for independent component analysis attaining the cramer-RAO lower bound

We propose an improved version of algorithm FastICA which is asymptotically efficient, i.e., its accuracy attains the Cramer-Rao lower bound provided that the probability distribution of the signal components belongs to the class of generalized Gaussian distribution. Its computational complexity is only slightly (about three times) higher than that of ordinary symmetric FastICA. Simulation section shows superior performance of the algorithm compared with JADE, and of non-parametric ICA
Calibration of multi-Kinect and multi-camera setup for full 3D reconstruction

In this paper, a new calibration method is presented for multi-Kinect and multi-camera setup. This method is developed by considering that the depth measurement principle of the Kinect is triangulation. The depth values obtained from the Kinect are sometimes inaccurate because the manufacturer's calibration between IR projector and IR camera becomes invalid by the tolerances in manufacturing, temperature variation and vibration during transportation. To improve the results from the previous calibration methods, an analytic approach is presented. Experiments show that the induced depth correction model is reasonable and the results from the proposed approach are better than those of the previous approaches.
[Diagnosis of herpetic uveitis and keratouveitis].

BACKGROUND In epithelial viral keratitis as in viral retinitis, the diagnosis is made on the basis of typical clinical findings. A laboratory confirmation is achieved in over 80% using routine laboratory methods. In contrast, it is almost impossible to confirm the diagnosis of stromal herpetic keratitis in vivo using the currently available laboratory methods. Nothing is known about the situation in cases of viral anterior uveitis. METHODS Of 52 patients with granulomatous anterior uveitis, 31 were diagnosed on the basis of clinical findings as active herpetic uveitis (group 1), 14 as active granulomatous uveitis of unknown origin (group 2), and 7 had inactive disease after quietening down of herpetic uveitis (group 3). From all patients, aqueous humor was collected at the time of diagnosis and processed for viral culture, Herpes antigen ELISA, and amplification of viral DNA of HSV-1 and VZV. RESULTS Viral growth in culture was found in only one case in group 3. In this group, viral antigen or viral DNA were detected in no case. Herpes antigen was found in 5/31 cases (16%) in group 1 and in 1/11 cases (9%) in group 2, and viral DNA was found in 8/31 cases from group 1 (5x HSV-1 and 3x VZV) and in 5/14 cases (31%) from group 2. After combination of antigen detection and DNA amplification, the presence of virus was confirmed in 14/45 cases (29%). CONCLUSION Virus culture has not proven useful in the diagnosis of viral anterior segment disease. Despite their high overall sensitivity, neither antigen ELISA nor the amplification of viral DNA proved sensitive enough to establish a viral etiology. Nevertheless, a laboratory confirmation should be attempted in granulomatous uveitis of unknown origin after preclusion of an underlying systemic disease because of the consequences of a diagnosis of viral anterior segment disease for treatment and prognosis.
Effect of pregnancy on plasma lipid levels of Nigerian women.

Plasma cholesterol, triglyceride, phospholipid and fatty acid fractions of healthy pregnant women were investigated and found to rise significantly in the first trimester, followed by a fall in the second and subsequent rise again in the third trimester or near term (p <0.01). ®f all the lipid classes determined, the phospholipid fraction had the highest increase (94%) at near term and had the highest concentration in the plasma (350.85±22.85 mg/ 100 ml). This was followed by free fatty acid (64%; 78.52± 13.66 mmol/ 100 ml), total cholesterol (58%; 293.00± 18.58 mg/ 100 ml), and triglyceride (38%; 203.00± 13.40 mg/ 100 ml) fractions. Whereas phospholipids and triglyceride levels increased with parity, total cholesterol and fatty acid levels showed appreciable decreases with multiparity. There was no significant correlation between plasma lipid level and body weight or age of the pregnant women (p>0.05). Social class, an index of nutritional status, was found to be highly correlated with plasma lipid levels (p<0.05; r= +0.842). The significance of this to fetal quality and survival is discussed.
Toxic activity of Bacillus sphaericus SSII-1 for mosquito larvae

Using larvae of the mosquito Culex pipiens var. quinquefasciatus as a bioassay system, we have verified an earlier proposal that pathogenicity of Bacillus sphaericus SSII-1 is a toxin-mediated rather than an infectious process. Chloroform or ultraviolet-light treatments that decreased the viable count of SSII-1 cells by 4 or 5 logs did not significantly alter the ability of the bacterial cells to kill larvae. Three lines of evidence indicated that toxic activity was not related to sporulation: (i) cells grown in either a complex or a defined medium were toxic at all ages; (ii) when supplemental Mn2+ was excluded from a complex medium, the culture yielded few spores but was of equal toxicity to a culture containing many spores; and (iii) several early blocked oligosporogenous mutants were isolated that had toxic activities comparable to that of the parent. The toxin was shown to be relatively unstable because activity was destroyed by heat and decreased by refrigeration, a freeze-thaw cycle, or two methods of cell breakage. Thin sections of SSII-1 cells did not reveal the presence of any inclusion body that might be related to toxicity.
Rethinking programme evaluation in health professions education: beyond ‘did it work?’

Context For nearly 40 years, outcome‐based models have dominated programme evaluation in health professions education. However, there is increasing recognition that these models cannot address the complexities of the health professions context and studies employing alternative evaluation approaches that are appearing in the literature. A similar paradigm shift occurred over 50 years ago in the broader discipline of programme evaluation. Understanding the development of contemporary paradigms within this field provides important insights to support the evolution of programme evaluation in the health professions.
Vorkommen und Verbreitung Fruchtkörper-bildender Myxobakterien im Siebengebirge Vergleichende Untersuchungen unter Berücksichtigung charakteristischer Biotope

In the region of the “Siebengebirge” near Bonn, six characteristic biotopes were studied with respect to the occurrence of fruiting body forming myxobacteria. 23 different species, belonging to the 8 known genera, were found. The number of species in the respective biotopes varied between 6 and 17, the average numbers of species per sampling area were between 2.1 and 10.0. 15 species were found on dung pellets of wild living herbivorous mammals. Deciduous forest soils contained 13 species in spring, 17 species in autumn. Rock covering contained 14, creek slopes 16, bark of living trees 9, and rotting wood 16 fruiting myxobacterial species. Myxococcus fulvus, Myxococcus coralloides and Archangium gephyra occurred in all biotops studied. The rare species were Melittangium boletus, Polyangium vitellinum, Stigmatella aurantiaca, and Chondromyces apiculatus. The composition of the myxobacterial flora depends on ecological factors (kind of dung pellets, rock, bark, and pH). The ecological influences upon the distribution are discussed.
In vivo imaging of retinoic acid receptor β2 transcriptional activation by the histone deacetylase inhibitor MS‐275 in retinoid‐resistant prostate cancer cells

In retinoid resistant epithelial tumors, the lack of retinoic acid receptor β2 (RARβ2) expression due to epigenetic silencing impairs the activation of retinoid target genes including RARβ2, and has been associated with the development of cancer. In this study we developed a strategy to monitor the re‐activation of RARβ2 by chromatin remodeling agents combined with retinoids in real time, and to correlate the RARβ2 re‐activation with anti‐tumor activity.
Silicon photonic microring components for on-chip WDM networks

Silicon photonics has matured to become an important platform for photonics integrated circuits (PICs) due to its compatibility with the CMOS process, which enables electronics and photonics to be integrated on the same chip. One of the main applications driving silicon photonics is on-chip WDM networks for optical interconnects. These applications often require add-drop filters with high frequency selectivity and low group delay dispersion. In this paper we give an overview of recent progress in the development of advanced silicon PICs based on microring resonators for WDM filter applications. The issue of post-fabrication tuning of silicon components to correct for fabrication imperfections will also be addressed.