Miracle-dz/UniFAR-FTUs huggingface dataset:
Mining Temporally Evolving Graphs

Web mining has been explored to a vast degree and d ifferent techniques have been proposed for a variet y of applications that include Web Search, Web Classific at on, Web Personalization etc. Most research on We b mining has been from a ‘data-centric’ point of view. The f ocus has been primarily on developing measures and applications based on data collected from content, structure and usage of Web till a particular time instance. In t his project we examine another dimension of Web Mining, namely tem poral dimension. Web data has been evolving over ti me, reflecting the ongoing trends. These changes in dat a in the temporal dimension reveal new kind of info rmation. This information has not captured the attention of the W b mining research community to a large extent. In this paper, we highlight the significance of studying the evolv ing nature of the Web graphs. We have classified th approach to such problems at three levels of analysis: ingle node, sub-graphs and whole graphs. We provide a framework to approach problems of this kind and have identified interesting problems at each level. Our experiments verify the significance of such analysis and also point to fut ure directions in this area. The approach we take i s generic and can be applied to other domains, where data can be mode led as graph, such as network intrusion detection o r social networks.
Steady locomotion in dogs: temporal and associated spatial coordination patterns and the effect of speed

SUMMARY Only a few studies on quadrupedal locomotion have investigated symmetrical and asymmetrical gaits in the same framework because the mechanisms underlying these two types of gait seem to be different and it took a long time to identify a common set of parameters for their simultaneous study. Moreover, despite the clear importance of the spatial dimension in animal locomotion, the relationship between temporal and spatial limb coordination has never been quantified before. We used anteroposterior sequence (APS) analysis to analyse 486 sequences from five malinois (Belgian shepherd) dogs moving at a large range of speeds (from 0.4 to 10.0 m s–1) to compare symmetrical and asymmetrical gaits through kinematic and limb coordination parameters. Considerable continuity was observed in cycle characteristics, from walk to rotary gallop, but at very high speeds an increase in swing duration reflected the use of sagittal flexibility of the vertebral axis to increase speed. This change occurred after the contribution of the increase in stride length had become the main element driving the increase in speed– i.e. when the dogs had adopted asymmetrical gaits. As the left and right limbs of a pair are linked to the same rigid structure, spatial coordination within pairs of limbs reflected the temporal coordination within pairs of limbs whatever the speed. By contrast, the relationship between the temporal and spatial coordination between pairs of limb was found to depend on speed and trunk length. For trot and rotary gallop, this relationship was thought also to depend on the additional action of trunk flexion and leg angle at footfall.
Hyalomma asiaticum asiaticum Schülze and Schlottke, 1929. Its distribution, hosts, seasonal activity, life cycle, and role in transmission of bovine theileriosis in Iran.

Hyalomma a. asiaticum is confirmed to be a distinct species which occurs in many parts of Iran except near the Caspian Sea. The main hosts of adults are sheep; cattle, horses, goats, and camels are also infested. Adults were collected in each season but their activity was found to be in spring, especially in May. This is strictly a three-host tick and a vector of Theileria annulata.
Cardiac Actions of Glucagon

Glucagon increased heart rate and contractile force in the anesthetized dog and increased isometric tension in the isolated dog papillary muscle. The positive inotropic and chronotropic responses were not abolished or reduced by previous administration of the beta-receptor blocking agent propranolol, in doses of 0.5 mg/kg. Glucagon increased the force and rate of cardiac contraction even when cardiac-depressant doses of propranolol, 2 mg/kg, had been given. Previous treatment with reserpine (1.0 mg/kg on each of 3 consecutive days) failed to diminish the positive inotropic and chronotropic effects of glucagon. However, previous administration of tyramine, 0.05 mg/kg, which resulted in a positive inotropic response in the dog, significantly reduced the glucagon-induced positive inotropic response. Theophylline, 10 mg/kg, likewise prevented the inotropic action of glucagon without preventing the positive inotropic effect of calcium chloride. The increase in isometric tension produced by glucagon in the isolated dog papillary muscle was prevented during simultaneous exposure of the muscles to acetylcholine. The results of these studies are discussed in reference to the known metabolic actions of glucagon and the catecholamines and the possibility that they both share a common mechanism of action mediated through an increase in the intracellular concentration of cyclic 3′,5′ AMP.
Blood lactate accumulation and muscle deoxygenation during incremental exercise.

Near-infrared spectroscopy (NIRS) could allow insights into controversial issues related to blood lactate concentration ([La](b)) increases at submaximal workloads (). We combined, on five well-trained subjects [mountain climbers; peak O(2) consumption (VO(2peak)), 51.0 +/- 4.2 (SD) ml. kg(-1). min(-1)] performing incremental exercise on a cycle ergometer (30 W added every 4 min up to voluntary exhaustion), measurements of pulmonary gas exchange and earlobe [La](b) with determinations of concentration changes of oxygenated Hb (Delta[O(2)Hb]) and deoxygenated Hb (Delta[HHb]) in the vastus lateralis muscle, by continuous-wave NIRS. A "point of inflection" of [La](b) vs. was arbitrarily identified at the lowest [La](b) value which was >0.5 mM lower than that obtained at the following. Total Hb volume (Delta[O(2)Hb + HHb]) in the muscle region of interest increased as a function of up to 60-65% of VO(2 peak), after which it remained unchanged. The oxygenation index (Delta[O(2)Hb - HHb]) showed an accelerated decrease from 60- 65% of VO(2 peak). In the presence of a constant total Hb volume, the observed Delta[O(2)Hb - HHb] decrease indicates muscle deoxygenation (i.e., mainly capillary-venular Hb desaturation). The onset of muscle deoxygenation was significantly correlated (r(2) = 0.95; P < 0.01) with the point of inflection of [La](b) vs., i.e., with the onset of blood lactate accumulation. Previous studies showed relatively constant femoral venous PO(2) levels at higher than approximately 60% of maximal O(2) consumption. Thus muscle deoxygenation observed in the present study from 60-65% of VO(2 peak) could be attributed to capillary-venular Hb desaturation in the presence of relatively constant capillary-venular PO(2) levels, as a consequence of a rightward shift of the O(2)Hb dissociation curve determined by the onset of lactic acidosis.
Development of pulse-plating technology for the preparation of coatings with varying composition along their thickness: a historical overview

ABSTRACT Electrodeposition has long been used for the preparation of coatings consisting either of a single metal or a combination of two or more metals in the form of an alloy. At a certain level of technological development, the demand arose to obtain coatings which can combine the advantageous properties of different metals none of which alone nor any of their mutual alloy combinations can offer the desired properties. This need was the driving force behind the development of electrodeposition methods to produce layered coatings consisting of alternating constituent layers with widely different behaviour. These so-called ‘compositionally graded coatings’ can be compositionally modulated alloys or multilayers. In the present contribution, a historical overview of the development of various pulse-plating methods for the preparation of compositionally graded coatings from a single bath is given. The most common procedure is the use of a repetition of a pulse sequence. This sequence consists of two or more consecutive deposition pulses of different lengths, current densities and/or deposition potentials. As a particular case, the historical development of corrosion-protective electrodeposited multilayers based on the Zn–Fe system and the state of the art of the system is described.
p53 Regulates the Neuronal Intrinsic and Extrinsic Responses Affecting the Recovery of Motor Function following Spinal Cord Injury

Following spinal trauma, the limited physiological axonal sprouting that contributes to partial recovery of function is dependent upon the intrinsic properties of neurons as well as the inhibitory glial environment. The transcription factor p53 is involved in DNA repair, cell cycle, cell survival, and axonal outgrowth, suggesting p53 as key modifier of axonal and glial responses influencing functional recovery following spinal injury. Indeed, in a spinal cord dorsal hemisection injury model, we observed a significant impairment in locomotor recovery in p53−/− versus wild-type mice. p53−/− spinal cords showed an increased number of activated microglia/macrophages and a larger scar at the lesion site. Loss- and gain-of-function experiments suggested p53 as a direct regulator of microglia/macrophages proliferation. At the axonal level, p53−/− mice showed a more pronounced dieback of the corticospinal tract (CST) and a decreased sprouting capacity of both CST and spinal serotoninergic fibers. In vivo expression of p53 in the sensorimotor cortex rescued and enhanced the sprouting potential of the CST in p53−/− mice, while, similarly, p53 expression in p53−/− cultured cortical neurons rescued a defect in neurite outgrowth, suggesting a direct role for p53 in regulating the intrinsic sprouting ability of CNS neurons. In conclusion, we show that p53 plays an important regulatory role at both extrinsic and intrinsic levels affecting the recovery of motor function following spinal cord injury. Therefore, we propose p53 as a novel potential multilevel therapeutic target for spinal cord injury.
PHARMACOLOGICAL INVESTIGATIONS ON FRUITS OF WITHANIA COAGULANS, Dunal

Pharmacological investigations with alcoholic extract, total alkaloids and aqueous extract of the fruits of W i t hania coagulans showed the presence of central nervous system depressant effect characterised by decreased spontaneous activity and potentiation of pentobarbitone hypnosis. However, the extracts showed no analgesic and anticonvulsant activity. In addition, alcoholic extract and total alkaloids showed a significant antiinflammatory effect in acute inflammation induced with egg albumin, subacute inflammation induced with formalin and granulation tissue formation by cotton pellet method
Vibrational Modes and the Dynamic Solvent Effect in Electron and Proton Transfer

This article primarily reviews recent work on ultrafast experiments on excited state intramolecular electron and proton transfer, with an emphasis on experiments on chemical systems that have been analyzed theoretically. In particular, those systems that have been quantitatively characterized by static spectroscopy, which provides detailed information about the reaction potential energy surface and about other parameters that are necessary to make a direct comparison to theoretical predictions, are described.
A geometry-based coverage strategy over urban VANETs

Vehicular ad hoc networks have emerged as a promising field in wireless networking research. Unlike traditional wireless sensor networks, vehicular networks demand more consideration due to their assorted road topology, the high mobility of vehicles and the irregularly placed feasible region of deployment. As one of the most complex issues in vehicular networks, coverage strategy has been researched extensively, especially in complex urban scenarios. However, most existing coverage approaches are based on an ideal traffic map consisting of straight lines and nodes. These simplifications misrepresent the road networks. In order to provide more realistic vehicular networks deployment, this paper proposes a geometry-based coverage strategy to handle the deployment problem over urban scenarios. By taking the shape and area of road segments into account, our scheme suits different kinds of road topology and effectively solves the maximum coverage problem. To evaluate the effectiveness of our scheme, we compare this coverage strategy with α-coverage algorithm. The simulation result verifies that geometry-based coverage strategy culminates in a higher coverage ratio and a lower drop rate than α-coverage under the same constraints. The results also show that the deployment of Road Side Units (RSUs) in regions with high traffic flow is able to cover the majority of communication, so that less RSUs are able to provide better communication performance.
Fast Feedback Cycles in Empirical Software Engineering Research

Background/Context: Gathering empirical knowledge is a time consuming task and the results from empirical studies often are soon outdated by new technological solutions. As a result, the impact of empirical results on software engineering practice is often not guaranteed.Objective/Aim: In this paper, we summarise the ongoing discussion on "Empirical Software Engineering 2.0" as a way to improve the impact of empirical results on industrial practices. We propose a way to combine data mining and analysis with domain knowledge to enable fast feedback cycles in empirical software engineering research.Method: We identify the key concepts on gathering fast feedback in empirical software engineering by following an experience-based line of reasoning by argument. Based on the identified key concepts, we design and execute a small proof of concept with a company to demonstrate potential benefits of the approach.Results: In our example, we observed that a simple double feedback mechanism notably increased the precision of the data analysis and improved the quality of the knowledge gathered.Conclusion: Our results serve as a basis to foster discussion and collaboration within the research community for a development of the idea.
Physical and Mental Comorbidity, Disability, and Suicidal Behavior Associated With Posttraumatic Stress Disorder in a Large Community Sample

Objective: To assess if posttraumatic stress disorder (PTSD), recognized as a common mental disorder in the general population and veteran samples, has a unique impact on comorbidity, disability, and suicidal behavior (after adjusting for other mental disorders, especially depression). Methods: Data came from the Canadian Community Health Survey Cycle 1.2 (n = 36,984; age ≥15 years; response rate 77%). All respondents were asked if they had been given a diagnosis of PTSD by a healthcare professional. A select number of mental disorders were assessed by the Composite International Diagnostic Interview. Chronic physical health conditions, measures of quality of life, disability, and suicidal behavior were also assessed. Results: The prevalence of PTSD as diagnosed by health professionals was 1.0% (95% CI = 0.90–1.15). After adjusting for sociodemographic factors and other mental disorders, PTSD remained significantly associated with several physical health problems including cardiovascular diseases, respiratory diseases, chronic pain conditions, gastrointestinal illnesses, and cancer. After adjusting for sociodemographic factors, mental disorders, and severity of physical disorders, PTSD was associated with suicide attempts, poor quality of life, and short- and long-term disability. Conclusions: PTSD was uniquely associated with several physical disorders, disability, and suicidal behavior. Increased early recognition and treatment of PTSD are warranted. PTSD = posttraumatic stress disorder; CCHS 1.2 = Canadian Community Health Survey cycle 1.2; CI = confidence interval; WBMMS = Psychological Well-Being Manifestation Scale.
Recent advances in the application of capillary electromigration methods for food analysis

This article reviews the latest developments in the application of capillary electromigration methods for the analysis of foods and food components. Nowadays, methods based on CE techniques are becoming widely used in food analytical and research laboratories. This review covers the application of CE to analyze amino acids, biogenic amines, peptides, proteins, DNAs, carbohydrates, phenols, polyphenols, pigments, toxins, pesticides, vitamins, additives, small organic and inorganic ions, chiral compounds, and other compounds in foods, as well as to investigate food interactions and food processing. The use of microchips as well as other foreseen trends in CE analysis of foods is discussed. Papers that were published during the period June 2002–June 2005 are included following the previous review by Frazier and Papadopoulou (Electrophoresis 2003, 24, 4095–4105).
Sustained alignment of nanocellulose from magnetic field exposure

A method to sustain the alignment of nanocellulose, which a magnetic field induces in a solution of cellulose crystals, was tested. The nanocellulose was modified to incorporate metal chelating cysteine groups through oxidations and Schiff base coupling. Water solutions of the modified cellulose was exposed to a magnetic field of one Tesla. To stabilise the alignment iron ions were added to the solutions. The material was topographically studied with scanning electron microscopy. The results were inconclusive due to inadequate field exposure.
Virtual release advancing for earlier deadlines

Giving tasks more urgent deadlines leads to shorter response times in EDF-based scheduling. This paper describes a technique that gives earlier deadlines by virtually advancing release times in the Total Bandwidth Server (TBS) context. This technique improves aperiodic tasks' responsiveness while it guarantees the schedulability of the system. Simulations show the technique outperforms TBS and its enhanced one.
DEsubs: an R package for flexible identification of differentially expressed subpathways using RNA-seq experiments

DEsubs is a network-based systems biology R package that extracts disease-perturbed subpathways within a pathway network as recorded by RNA-seq experiments. It contains an extensive and customized framework with a broad range of operation modes at all stages of the subpathway analysis, enabling so a case-specific approach. The operation modes include pathway network construction and processing, subpathway extraction, visualization and enrichment analysis with regard to various biological and pharmacological features. Its capabilities render DEsubs a tool-guide for both the modeler and experimentalist for the identification of more robust systems-level drug targets and biomarkers for complex diseases. AVAILABILITY AND IMPLEMENTATION DEsubs is implemented as an R package following Bioconductor guidelines: http://bioconductor.org/packages/DEsubs/ CONTACT: tassos.bezerianos@nus.edu. sgSupplementary information: Supplementary data are available at Bioinformatics online.
Product Approximate Reasoning of Online Reviews Applying to Consumer Affective and Psychological Motives Research

Consumer psychology and sentiment analysis become more and more flourishing. This paper presents fuzzy inference rules with comprehensive evaluation and emotion as antecedents and accomplishes reasoning recommendation to consumers with four different motivations. A fuzzy model for the evaluation and emotion of online review texts is proposed using the theory of consumption motivation type. It has an inbuilt fuzzy corpus of consumer evaluation and emotion and has given a calculational method of comprehensive evaluation and emotion combined with the consumer’s preference for product attributes.
Baseline Participant Characteristics and Risk for Dropout from 10 Obesity Randomized Controlled Trials: A Pooled Analysis of Individual Level Data

Introduction: Understanding participant demographic characteristics that inform the optimal design of obesity randomized controlled trials (RCTs) have been examined in few studies. The objective of this study was to investigate the association of individual participant characteristics and dropout rates (DORs) in obesity RCTs by pooling data from several publicly available datasets for analyses. We comprehensively characterize DORs and patterns in obesity RCTs at the individual study level, and describe how such rates and patterns vary as a function of individual level characteristics. Methods: We obtained and analyzed nine publicly available, obesity RCT datasets that examined weight loss or weight gain prevention as a primary or secondary endpoint. Four risk factors for dropout were examined by Cox proportional hazards including sex, age, baseline BMI, and race/ethnicity. The individual study data were pooled in the final analyses with a random effect for study, and HR and 95% CIs were computed. Results: Results of the multivariate analysis indicated that the risk of dropout was significantly higher for females compared to males (HR = 1.24, 95% CI = 1.05, 1.46). Hispanics and Non-Hispanic blacks had a significantly higher dropout rate compared to non-Hispanic whites (HR = 1.62, 95% CI = 1.37, 1.91; HR = 1.22, 95% CI = 1.11, 1.35, respectively). There was a significantly increased risk of dropout associated with advancing age (HR = 1.02, 95% CI = 1.01, 1.02) and increasing BMI (HR = 1.03, 95% CI = 1.03, 1.04). Conclusion/Significance: As more studies may focus on special populations, researchers designing obesity RCTs may wish to oversample in certain demographic groups if attempting to match comparison groups based on generalized estimates of expected DORs, or otherwise adjust a priori power estimates. Understanding true reasons for dropout may require additional methods of data gathering not generally employed in obesity RCTs, e.g., time on treatment.
Semantics-Based Machine Translation with Hyperedge Replacement Grammars

We present an approach to semantics-based statistical machine translation that uses synchronous hyperedge replacement grammars to translate into and from graph-shaped intermediate meaning representations, to our knowledge the first work in NLP to make use of synchronous context free graph grammars. We present algorithms for each step of the semantics-based translation pipeline, including a novel graph-to-word alignment algorithm and two algorithms for synchronous grammar rule extraction. We investigate the influence of syntactic annotations on semantics-based translation by presenting two alternative rule extraction algorithms, one that requires only semantic annotations and another that additionally relies on syntactic annotations, and explore the effect of syntax and language bias in meaning representation structures by running experiments with two different meaning representations, one biased toward an English syntax-like structure and another that is language neutral. While preliminary work, these experiments show promise for semantically-informed machine translation.
Expansion of mouse sertoli cells on microcarriers

Background: Sertoli cells (SCs) have been described as the ‘nurse cells’ of the testis whose primary function is to provide essential growth factors and create an appropriate environment for development of other cells [for example, germinal and nerve stem cells (NSCs), used here]. However, the greatest challenge at present is that it is difficult to obtain sufficient SCs of normal physiological function for cell transplantation and biological medicine, largely due to traditional static culture parameter difficult to be monitored and scaled up.
Integral equation for guided-wave problems and application to magneto-plasmonics in graphene

A novel modal electric field integral equation (EFIE) is introduced for the analysis of waveguiding problems for which the Green function is available in closed form. This method is much more efficient than finite-difference and finite-element techniques. The proposed EFIE is applied to simulate magneto-plasmons in a magnetically biased graphene strip.