Miracle-dz/UniFAR-FTUs huggingface dataset:
GUI – Enhanced Activity Diagarams with Application to the Design of AVISTED

Software design is worthwhile if it paves the way to a good and useful functional software. In this paper, we propose a new tool entitled GUI-Enhanced Activity diagrams (GEAD). This tool facilitates a new approach of software design consisting of UML activity diagrams with links to their respective interface snapshots. Notably, GEAD is more efficient for web applications that have numerous graphical user interfaces. To illustrate GEAD, we introduce a new toolset entitled ‘Analysis and Visualization Toolset for Environmental Data’ (AVISTED). AVISTED is a generic web-based visualization toolset which is used by climate researchers for visualizing large climate datasets. This paper introduces the design aspects of AVISTED by leveraging the concepts and strategies of GEAD. The links between the designs of the webpages and the activities in UML diagrams help showing clear connections between the backend and frontend activities. This comprehensive view helps developing the desired software that meets the user requirements more efficiently by improving collaboration and decreasing development time.
Wavelet neural network based on MSUKF and its applications in chaotic time series prediction

Wavelet neural network (WNN) trained by unscented Kalman filter (UKF) has many merits of fast convergent rate and small prediction error without computing the Jacobian matrix. Based on this, an improved UKF is introduced into the parameters estimation for WNN. The algorithm uses an unscented transform (UT) based on minimal skew simplex Sigma point sampling strategy in the frame of Kalman filter, which not only inherits all the merits of UKF, but also increases the computational efficiency. The experimental results for chaotic time series prediction show that WNN of the improved UKF has the faster training speed and higher prediction precision than that of EKF, and has a similar precision with that of UKF but high computational efficiency. In addition, it has also a good applicability to the chaotic time series prediction.
GPR30 estrogen receptor agonists induce mechanical hyperalgesia in the rat

We evaluated the signalling pathway by which estrogen acts in peripheral tissue to produce protein kinase Cɛ (PKCɛ)‐dependent mechanical hyperalgesia. Specific agonists for the classical estrogen receptors (ER), ERα and ERβ, did not result in activation of PKCɛ in neurons of dissociated rat dorsal root ganglia. In contrast, G‐1, a specific agonist of the recently identified G‐protein‐coupled estrogen receptor, GPR30, induced PKCɛ translocation. Involvement of GPR30 and independence of ERα and ERβ was confirmed using the GPR30 agonist and simultaneous ERα and ERβ antagonist ICI 182,780 (fulvestrant). The GPR30 transcript could be amplified from dorsal root ganglia tissue. We found estrogen‐induced as well as GPR30‐agonist‐induced PKCɛ translocation to be restricted to the subgroup of nociceptive neurons positive for isolectin IB4 from Bandeiraea simplicifolia. Corroborating the cellular results, both GPR30 agonists, G‐1 as well as ICI 182,780, resulted in the onset of PKCɛ‐dependent mechanical hyperalgesia if injected into paws of adult rats. We therefore suggest that estrogen acts acutely at GPR30 in nociceptors to produce mechanical hyperalgesia.
On Knowledge Structures Reduction

Matrix reduction and formal concept analysis are two complementary mathematical tools for data analysis. In this paper, we study the reduction of the concept lattices and implication bases based on matrix reduction and propose two kinds of reduction methods for the above concept lattices. We analyse the benefits which we obtain by using several methods of matrix factorisation to reduce the dimension of input data.
An Efficient Support Vector Machine Algorithm for Solving Multi-class Pattern Recognition Problems

In this paper, an efficient support vector machine (SVM) algorithm for solving multi-class pattern recognition problems is proposed. The samples in each class are trained by one-class SVM (OCSVM), respectively. And then several sets of support vectors (SVs) are obtained, which well express the distribution of the original training samples. These SVs finally are combined into a set of training samples and trained by one-versus-one (OVO) method. The experimental results show the proposed method can reduce the time of training procedure meanwhile the classification accuracy is not reduced. Furthermore, it generates less SVs than traditional way.
Structural and functional characterization of the mouse Sox9 promoter: implications for campomelic dysplasia.

Mutations in SOX9 cause campomelic dysplasia (CD), a dominant skeletal dysmorphology and XY sex reversal syndrome. The CD phenotype is sensitive to dosage and expression levels of SOX9. Sox9 is expressed during chondrocyte differentiation and is up-regulated in male and down-regulated in female genital ridges during sex differentiation. In order to study the sex- and tissue-specific regulation of Sox9, we have defined the transcription start site and characterized the mouse Sox9 promoter region. The Sox9 proximal promoter shows moderately high nucleotide similarity between mouse and human. Transient transfection experiments using various deletion constructs of the 6.8 kb upstream region of mouse Sox9 fused to a luciferase reporter showed that the interval between 193 and 73 bp from the transcription start site is essential for maximal promoter activity in cell lines and in primary male and female gonadal somatic cells and liver cells isolated from 13.5 d.p.c. mouse embryos. This minimal promoter region was shown by DNase I hypersensitive site assay to be in an 'open' state of chromatin structure in gonads of both sexes, but not in the liver. Promoter activity was higher in testis than in ovary and liver, but deletion of the region from -193 to -73 bp abolished this difference. We conclude that the proximal promoter region is in part responsible for the sex- and tissue-specific expression of the Sox9 gene and that more distal positive and negative elements contribute to its regulation in vivo, consistent with the observation that translocations upstream from SOX9 can result in campomelic dysplasia.
Automated Detection of Rockfish in Unconstrained Underwater Videos Using Haar Cascades and a New Image Dataset: Labeled Fishes in the Wild

This article presents methods applied for automated detection of fish based on cascade classifiers of Haar-like features created using underwater images from a remotely operated vehicle under ocean survey conditions. The images are unconstrained, and the imaging environment is highly variable due to the moving imaging platform, a complex rocky seabed background, and still and moving cryptic fish targets. These images are released in a new image dataset, "labeled fishes in the wild," of in situ groundfishes, mainly rockfishes (Sebastes spp.) and other associated species. The dataset includes an annotated training and validation image set, as well as an independent test video image sequence. Several Haar cascades are developed from the training set and applied to the validation and test video images for evaluation. Based on performance evaluation using the validation set, true positive detection rates of 63 to 89% were achieved for seven classifiers. True positive detection rates for the test video were 66% to 81% for analyst-confirmed fish targets. Detector performance is dependent on training data, training and detection parameters, fish orientation, range to target, variable light intensity and attenuation.
Comparison of graph sampling algorithms using normalized Laplacian spectra

The normalized Laplacian spectrum is a good indicator of connectivity for comparing graphs with different sizes (i.e., the number of nodes). This paper shows the performances of several random-walk sampling algorithms using the spectral indicator. Based on two types of complex network models with exponential and power-law degree distributions, we determine that the sampling algorithms do not perform well on the spectral indicator, and find that the spectral indicator of biased sampling graphs is much closer to that of original graphs when the assortative mixing coefficient of original graphs decreases. Especially, for disassortative networks, biased sampling graphs perform better than unbiased sampling graphs on the spectral indicator.
Log-Based Anomaly Detection of CPS Using a Statistical Method

Detecting anomalies of a cyber physical system (CPS), which is a complex system consisting of both physical and software parts, is important because a CPS often operates autonomously in an unpredictable environment. However, because of the ever-changing nature and lack of a precise model for a CPS, detecting anomalies is still a challenging task. To address this problem, we propose applying an outlier detection method to a CPS log. By using a log obtained from an actual aquarium management system, we evaluated the effectiveness of our proposed method by analyzing outliers that it detected. By investigating the outliers with the developer of the system, we confirmed that some outliers indicate actual faults in the system. For example, our method detected failures of mutual exclusion in the control system that were unknown to the developer. Our method also detected transient losses of functionalities and unexpected reboots. On the other hand, our method did not detect anomalies that were too many and similar. In addition, our method reported rare but unproblematic concurrent combinations of operations as anomalies. Thus, our approach is effective at finding anomalies, but there is still room for improvement.
Outcome and prognostic factors in advanced Hodgkin's disease treated with high-dose chemotherapy and autologous stem cell transplantation: a study of 341 patients.

BACKGROUND The reported probability of survival of patients with Hodgkin's disease (HD) following high-dose chemotherapy with autologous stem cell transplantation (HDC/ASCT) is 35-65% at 5 years. The Polish Lymphoma Research Group investigated retrospectively prognostic factors for overall survival (OS) and event-free survival (EFS), and the risk of secondary malignancies in a large series of patients who underwent HDC/ASCT. PATIENTS AND METHODS The data of 341 consecutive patients treated in 10 centers from 1990 to 2002 were collected and analyzed. RESULTS The actuarial 5-year OS and EFS were 64% [95% confidence interval (CI) 57% to 71%] and 45% (95% CI 39% to 51%), respectively. In the multivariate model, unfavorable prognostic factors for EFS were less than partial response at the time of ASCT [relative risk (RR), 2.92 (95% CI 1.68-5.08); P<0.001] and three or more previous chemotherapy lines (RR, 2.16; 95% CI 1.42-3.30; P<0.001). These two factors were also associated with unfavorable OS (RR, 3.32; 95% CI 1.90-5.79; P<0.001 and RR, 2.34, 95% CI 1.51-3.64; P<0.001). Five-year cumulative risk of secondary malignancy was 8.4% (95% CI 2% to 13%) and the only identified risk factor was splenectomy (P=0.02). CONCLUSIONS HDC/ASCT should be considered early in the course of disease for patients with a response after standard therapy.
Experimental Characterization of Interference in a 802.11g Wireless Mesh Network

— Multi-channel wireless networks are being studied as a means to increase wireless network capacity. The implicit assumption is that network throughput increases in direct proportion with the number of non-overlapping channels used. But there have been very few studies which have experimentally verified this premise. In this paper we characterize the performance of multi-channel wireless networks consisting of IEEE 802.11g devices. We conducted our experiments on a sample topology consisting of just two flows on non-overlapping channels. We expected the combined throughput of the two flows to double. However, our results showed that the expected increase in throughput is seen only when the separation between the antennas of the radio devices is above a threshold value. In our experimental setup, we observed a reduction of 25-40% in the expected total throughput value of the two flows. Further, we show that the effect of interference also varied with the transmission power of the radio devices and the packet size of individual flows. We believe that our results will be important when configuring a multi-channel wireless network using off-the-shelf devices.
Serum Ferritin Is Inversely Correlated with Testosterone in Boys and Young Male Adolescents: A Cross-Sectional Study in Taiwan

Objective The transition from childhood to teenaged years is associated with increased testosterone and a decreased iron status. It is not clear whether higher testosterone levels cause the decreased iron status, and to what extent, obesity-related inflammation influences the iron-testosterone relationship. The aim of the present study was to examine relationships of testosterone, iron status, and anti-/proinflammatory cytokines in relation to nutritional status in boys and young adolescent Taiwanese males. Methods In total, 137 boys aged 7~13 yr were included. Parameters for obesity, the iron status, testosterone, and inflammatory markers were evaluated. Results Overweight and obese (ow/obese) boys had higher mean serum testosterone, interleukin (IL)-1β, and nitric oxide (NO) levels compared to their normal-weight counterparts (all p<0.05). Mean serum ferritin was slightly higher in ow/obese boys compared to normal-weight boys, but this did not reach statistical significance. A multiple linear regression showed that serum ferritin (β = -0.7470, p = 0.003) was inversely correlated with testosterone, while serum IL-10 (β = 0.3475, p = 0.009) was positively associated with testosterone after adjusting for covariates. When normal-weight boys were separately assessed from ow/obesity boys, the association between testosterone and serum ferritin became stronger (β = -0.9628, p<0.0001), but the association between testosterone and IL-10 became non-significant (β = 0.1140, p = 0.4065) after adjusting for covariates. In ow/obese boys, only IL-10 was weakly associated with serum testosterone (β = 0.6444, p = 0.051) after adjusting for age. Conclusions Testosterone and serum ferritin are intrinsically interrelated but this relationship is weaker in ow/obese boys after adjusting for age.
Utilization of matched pulses to improve fault detection in wire networks

A new concept to fault detection in wire networks, based on the properties of time reversal, is presented. The method, called the Matched Pulse approach (MP), propose to adapt the testing signal to the analyzed network, instead of using a predefined signal, as opposed to existing reflectometry methods. Through mathematical study and numerical simulations, we show the benefits of this technique. A physical interpretation is also presented to better understand the proposed approach.
Simultaneous object tracking and pedestrian detection using HOGs on contour

This paper presents a novel method for simultaneous pedestrian detection and tracking in image sequences. The motion detection and tracking are addressed in a common framework that employs a geometric active contour model, in which an evolving curve was formulated by the level set method. The pedestrian detection module is started after the curve evolution, which stops the propagating contour on the object boundary. The HOG features are extracted on a set of points located on a narrow band around the zero level set, and serve as cues for pedestrian detection. Experimental results demonstrate that the proposed HOG descriptor provides more information representing pedestrians' distinguishing shape features than the original one.
Reporting of Major Accidents : Concorde AFR 4590 in The Times , The Sun and BBC Online

Many complaints have recently been made against the media reporting of major accidents (Johnson, 2003). It has been argued that undue emphasis is placed on identifying the immediate causes of any failure, including human error or technical failure, in the hours following an adverse event. In consequence, the public can be misinformed about the complex nature of many technological failures. The following pages present what is arguably the first detailed review of media coverage of a major accident. In particular, we consider the way in which a tabloid newspaper, a broadsheet and an Internet news service covered the loss of Concorde flight AFR4590 in July 2000. Our analysis yields some surprising results. The broadsheet speculates most about the causes of the incident, the tabloid publishes the least. The journalists and editorial staff on these new sources present very few direct hypotheses about the potential causes of this accident. In contrast, the majority of the speculation in the media is presented in the form of direct quotations from experts many of whom criticise undue speculation in the aftermath of such adverse events. This provides at least a partial explanation for the relative amount of speculative material in each of the publications that were studied. Experts may have been more inclined to speculate for the more prestigious broadsheet than they were for the mass-market tabloid publication. Alternatively, it can be argued that the editorial staff on the tabloid focussed their analysis more directly on the facts that were available in the aftermath of this accident.
Webkorpora in Computerlinguistik und Sprachforschung Web Corpora for Computational Linguistics and Linguistic Research

In this article, we give an overview about the necessary steps to construct high-quality corpora from web texts. We first focus on web crawling and the pros and cons of the existing crawling strategies. Then, we describe how the crawled data can be linguistically pre-processed in a parallelized way that allows the processing of web-scale input data. As we are working with web data, controlling the quality of the resulting corpus is an important issue, which we address by showing how corpus statistics and a linguistic evaluation can be used to assess the quality of corpora. Finally, we show how the availability of extremely large, high-quality corpora opens up new directions for research in various fields of linguistics, computational linguistics, and natural language processing.
A meta heuristic for graph drawing: learning the optimal graph-drawing method for clustered graphs

The problem of finding a pleasant layout for a given graph is a key challenge in the field of information visualization. For graphs that are biased towards a particular property such as tree-like, star-like, or bipartite, a layout algorithm can produce excellent layouts—if this property is actually detected. Typically, a graph may not be of such a homogeneous shape but is comprised of different parts, or it provides several levels of abstraction each of which dominated by another property. The paper in hand addresses the layout of such graphs. It presents a meta heuristic for graph drawing, which is based on two ideas: (i) The detection and exploitation of hierarchical cluster information to unveil a graph's inherent structure. (ii) The automatic selection of an individual graph drawing method for each cluster.
Mapping of the central sulcus with functional MR: active versus passive activation tasks.

PURPOSE Our purpose was to assess the pattern of functional MR activation obtained with a passive sensory versus an active sensorimotor hand stimulus paradigm. METHODS Eight functional MR runs, four with an active sensorimotor (sponge-squeezing) task and four with a passive sensory (palm-finger brushing) reception, were acquired for each of 10 healthy volunteers. Activation maps were generated by thresholding cross-correlation maps. Regions of interests (ROIs) were drawn around the precentral and postcentral gyri on T1-weighted images according to established anatomic criteria, and the number of activated pixels inside the ROIs was ascertained. Displacement of the sensorimotor and sensory activation centroids within the ROIs from the central sulcus as well as from each other was measured. RESULTS Active sensorimotor stimulation produced a significantly greater number of activation pixels than did passive sensory stimulation. Run-to-run variability was equivalent between sensorimotor and sensory activation tasks. On average, the sensorimotor and sensory activation centroids were located in the postcentral gyrus, and their spatial locations were not significantly different. CONCLUSION Active and passive activation tasks produce largely equivalent results. Presurgical mapping of the sensorimotor area can be performed with functional MR imaging using a passive palm-finger brushing task in patients who are physically unable to perform active finger-tapping or hand-squeezing sensorimotor activation tasks.
Solution of Non-linear Sixth-order Two Point Boundary-value Problems Using Parametric Septic Splines

In this paper a family of numerical methods is developed for solution of non-linear sixth-order two-point boundary-value problems using parametric septic spline. It is shown that the new methods give approximations, which are better than existing spline methods. End equations of the spline are derived and truncation error is given. Convergence analysis is discussed through standard procedures. Three numerical examples are given to illustrate the practical applicability and efficiency of our methods.
A compact CPW fed modified circular patch antenna with stub for UWB applications

In this paper, a new coplanar waveguide CPW fed Modified Circular Patch Antenna (MCPA) is presented. The proposed antenna is designed to operate from 3 GHz to 12 GHz. It consists of a circular patch which is truncated from two sides with respect to feed line. A stub of optimized dimension is attached to other side at a proper location to achieve ultra wide band characteristics. The proposed antenna is printed on a dielectric substrate glass epoxy FR 4 substrate and fed by a 50 Ω CPW on the same layer, which can yield an ultra wide bandwidth (-10 dB reflection coefficient) with satisfactory radiation patterns. The radiation patterns in the x-z plane are relatively omnidirectional, whereas the y-z plane patterns are bidirectional similar to that of a monopole antenna. The performance and characteristics of the antenna are investigated in order to understand its operation. It is proposed that this antenna can be part of various ultra wideband communication systems.