Miracle-dz/UniFAR-FTUs huggingface dataset:
Experiências Internacionais e Desafios dos Governos dos Países na Transição da Contabilidade Pública para o Regime de Competência

O presente estudo tem como objetivo apresentar experiencias internacionais e os desafios enfrentados pelos Governos dos paises na transicao da contabilidade publica para o regime contabil de competencia. Sua contribuicao esta na atualizacao da literatura no que tange ao posicionamento dos governos de economias mundiais quanto a adocao do accrual basis em sua contabilidade e, principalmente, por evidenciar os principais procedimentos observados durante o processo de transicao. Para tratar a questao da pesquisa, sao discutidos os procedimentos recomendados pelo Study 14, desenvolvido pela International Federation of Accountants (IFAC), e pelo Modelo de Requerimentos Basicos (BRM, em ingles), proposto por Ouda (2008), e analisadas as experiencias monitoradas pelo IFAC nos Governos da Malasia, Malta e Suica; as experiencias relatadas na literatura (Romenia, Nova Zelândia e Australia); e a experiencia vivenciada pelo Governo brasileiro, por meio de informacoes coletadas no sitio da Secretaria do Tesouro Nacional do Brasil e em artigos academicos. Os resultados mostram que os Governos da Suica, Australia e Nova Zelândia ja adotam o regime de competencia integral e seguiram todos os procedimentos recomendados pelo Study 14 e pelo BRM. No caso da Romenia, apesar de utilizar o regime de competencia integral, nao adotou a maior parte dos procedimentos recomendados, o que pode explicar o fato de as informacoes geradas em sua contabilidade nao serem utilizadas nem pelos gestores e nem pelas autoridades governamentais. No caso dos Governos da Malasia e de Malta, definiram o ano de 2019 como data limite para a transicao para o regime de competencia integral. Quanto ao Brasil, adota-se o regime de competencia modificado, sem previsao para adocao integral do regime de competencia. Com relacao aos desafios observados no processo de transicao, destaca-se, nessa ordem, carencia de pessoal treinado, exigencias tecnologicas, falta de comprometimento da alta administracao, custo da conversao e impacto esperado sobre a situacao patrimonial e financeira divulgada.
Predictors of delayed social maturation and mental health disorders in young adults chronically ill since childhood

To ascertain the influence of juvenile-onset chronic physical diseases and associating factors of social environment on delayed social maturation and mental health disorders in young adults, we analysed a group of 407 (184 female, 223 male) subjects with these conditions and compared the results with those of 123 (63 female, 60 male) healthy controls studied at the age of 19 ? 25 years. The social maturation index was formed on the basis of a demographic interview, which also reviewed the state of social development and the family situation during childhood. Mental health disorders were assessed with a Present State Examination (PSE) interview analysed with the CATEGO program. With regard to social maturation at least half of the patients and controls were doing well, whereas for 29% (CI95, 25%? 33%) of the patients and 17% (CI95, 10%? 24%) of the controls the index showed delayed maturation. Subjects with poor social maturation were found most often among the disabled patients but also among the patients without severe diseases. The prevalence of PSE-CATEGO-identified psychiatric syndromes was equal in the patients and the controls (22% versus 20%). However, the patients with severe or disabling diseases had more severe psychiatric syndromes. The prevalences of depressive syndromes were also equal, but the depression of the patients was more often a profound affective disorder. Male sex, poor scholastic and vocational success, and social problems in the family during childhood were significantly associated with poor social maturation. On the other hand, the most significant predictors of mental health problems in young adults were female sex, family distress during childhood, and a severe disease. Juvenile-onset physical disease was considered to delay social maturation in some subjects and to deepen or modulate the clinical picture of mental health disorders. It is concluded that juvenile-onset physical diseases combined with family-related factors affect in different ways the social growth and psychiatric well-being. The results suggest that the subjects with chronic diseases during childhood should be thoroughly assessed by a child psychiatrist to evaluate the orientation of psychological development and the impact of the child's disease on the family and to ensure balanced psychological and social growth.
Self-Handicapping and Burnout

Self-handicapping is a process containing strategies of externalization in which an individual can excuse failure and internalize success. This study investigated the relationship of self-handicapping with measures of burnout. The Self-handicapping Scale and the Maslach Burnout Inventory were administered to 309 university students. Self-handicapping was positively correlated to emotional exhaustion, lowered personal accomplishment, and depersonalization. A structural equation model fit the data well and accounted for 20% of the variance in emotional exhaustion, 14% in lowered personal accomplishment, and 10% in depersonalization.
Anti-hyperglycemic and anti-hyperlipidemic effect of combined plant extract of Cassia auriculata and Aegle marmelos in streptozotocin (STZ) induced diabetic albino rats.

Cassia auriculata and Aegle marmelos are used extensively in the indigenous system of medicine as an anti-diabetic agent. The current investigation focuses on the serum insulin augmentation, anti-hyperglycemic and anti-hyperlipidemic property of a combined aqueous extracts of C.auriculata and A.marmelos on streptozotocin induced diabetic rats. The diabetes induced animals were fed with plant extracts at the increasing dosage of 250mg, 350mg and 450mg of body wt. The combined plant extracts administrated animals revealed a significant (P<0.001) increment of serum insulin levels, higher reduction in hyperglycemia and hyperlipidemia when compared to the diabetic control rats (P<0.001). The histological studies of the endocrine region of pancreas of diabetic animals revealed that shrinkage of β cells of islets of langerhans. The combined plant extracts treated animals revealed restoration of β-cells. The restoration of β cells was evident at higher dose level i.e. 450mg/by wt extracts fed groups.
Laguerre estimation under constraint at a single point

This paper presents a general methodology for nonparametric estimation of a function s related to a nonnegative real random variable X, under a constraint of type s(0) = c. Three dierent examples are investigated: the direct observations model (X is observed), the multiplicative noise model (Y = XU is observed, with U following a uniform distribution) and the additive noise model (Y = X + V is observed where V is a nonnegative nuisance variable with known density). When a projection estimator of the target function is available, we explain how to modify it in order to obtain an estimator which satises the constraint. We extend risk bounds from the initial to the new estimator. Moreover if the previous estimator is adaptive in the sense that a model selection procedure is available to perform the squared bias/variance trade-o, we propose a new penalty also leading to an oracle type inequality for the new constrained estimator. The procedure is illustrated on simulated data, for density and survival function estimation.
Tutorial on photoacoustic tomography

Abstract. Photoacoustic tomography (PAT) has become one of the fastest growing fields in biomedical optics. Unlike pure optical imaging, such as confocal microscopy and two-photon microscopy, PAT employs acoustic detection to image optical absorption contrast with high-resolution deep into scattering tissue. So far, PAT has been widely used for multiscale anatomical, functional, and molecular imaging of biological tissues. We focus on PAT’s basic principles, major implementations, imaging contrasts, and recent applications.
Adaptive OFDM Radar Waveform Design for Improved Micro-Doppler Estimation

We analyze the performance of a wideband orthogonal frequency division multiplexing (OFDM) signal in estimating the micro-Doppler frequency of a rotating target having multiple scattering centers. The use of a frequency-diverse OFDM signal enables us to independently analyze the micro-Doppler characteristics with respect to a set of orthogonal subcarrier frequencies. We characterize the accuracy of micro-Doppler frequency estimation by computing the Cramér-Rao bound (CRB) on the angular-velocity estimate of the target. Additionally, to improve the accuracy of the estimation procedure, we formulate and solve an optimization problem by minimizing the CRB on the angular-velocity estimate with respect to the OFDM spectral coefficients. We present several numerical examples to demonstrate the CRB variations with respect to the signal-to-noise ratios, number of temporal samples, and number of OFDM subcarriers. The improvement in estimation accuracy due to the adaptive waveform design is also analyzed numerically. A grid-based maximum likelihood estimation technique is applied to evaluate the corresponding mean-squared error performance.
A cross layer UWSN architecture for marine environment monitoring

Underwater sensor networks (UWSN) transpires as a powerful technique in marine monitoring that includes various applications such as oceanographic data collection, marine surveillance and pollution detection. Localization in UWSN is very challenging as the sensor nodes are in a 3D space and are always in passive movement. Thus providing scalable and efficient energy aware routing services and localization schemes has always been provocative. Depth based routing (DBR) is one of the routing protocols that has been in use to attend to the existing constraints of UWSN. Unlike most of the routing protocols that require full dimensional location information of the sensor nodes, DBR needs only the depth information for routing. Also an energy-efficient game theoretic model based on Single-leader-multi-follower Stackelberg game that follows a socially optimal Stackleberg-Nash-Cournot Equilibrium has been in use for topology control of unlocalized and localized sensor nodes that are closed to the surface. A cross layer UWSN architecture for marine environment monitoring is proposed that uses the adaptive neuro fuzzy based interference system to determine the depth of the sensor nodes and the game theoretic model for localization of the sensor nodes at the upper hull of the sea. Using the depth DBR protocol reports the events to the localized sensor nodes that are close to the sea surface which in turn forwards the reported events to the sink. This cross layer UWSN architecture proves to be energy efficient and apt for marine environment monitoring. The architecture is structured and simulated in Aqua-Sim.
Dimethyl 3,3′-diphenyl-2,2′-[(S)-thiophene-2,5-diylbis(carbonylazanediyl)]dipropanoate tetrahydrofuran monosolvate

The title compound, C26H26N2O6S·C4H8O, a solvated bis-amide derivative, is also a chiral amino acid ester with l-phenylalanine methyl ester groups as amine substituents. The thiophene-2,5-dicarboxamide core approximates C 2 point symmetry. The tetrahydrofuran solvent molecule is linked to the main molecule through an intermolecular N—H⋯O hydrogen bond. The central ring makes dihedral angles of 90.0 (2) and 76.5 (2)° with the pendant rings.
Preparation of MaDiTS corpus for Malay dialect translation and speech synthesis system

This paper presents our work in acquiring a Malay dialect translation and speech synthesis corpus. In this study, an architecture of speech corpus acquisition, which including Malay dialect translation and Malay dialect grapheme to phoneme (G2P), was proposed. The pronunciation dictionary for dialectal Malay was generated through G2P tool. As dialectal Malay is considered as scarce resource, dialectal translation rules were developed for translating standard Malay text into dialectal Malay. With this, Kelantanese Malay is chosen in this research as it is considered as one of the Malay dialect from Kelantan, which positioned in the northeast of Peninsular Malaysia. This dialect is very distinctive. Evaluation results showed that the selected sentences through proposed approach has a correlation coefficient of about 0.99, which mean that it is phonetically well balanced.
Correlation of adenosinergic activity with superior efficacy of clozapine for treatment of chronic schizophrenia: a double blind randomised trial

It has been proposed that a deficit of adenosinergic activity could contribute to the pathophysiology of schizophrenia. The authors undertook this study to further evaluate the level of adenosine deaminase (ADA) in patients with chronic schizophrenia treated with monotherapy of haloperidol, risperidone or clozapine and correlation between the ADA level with response to treatment.
Environmental leapfrogging in developing countries: A critical assessment and reconstruction

It has been suggested in recent years that developing countries need not pass through the dirty stages of industrial growth that marred the past of today's developed countries. Instead, they may be able to bypass these by leapfrogging straight to modern, clean technologies as an integral part of capacity addition. This article critically reviews existing approaches to leapfrogging. It argues that they are not only characterized by considerable ambiguity, but also based on an incomplete understanding of the technological and policy requirements of cleaner industrialization. Consequently, the article goes on to offer a number of suggestions as to how current approaches might be advanced so as to better meet the challenge of leapfrogging. Amongst these suggestions is greater clarification of the specific targets for leapfrogging and policy intervention to accelerate the development of technological capabilities needed to select, absorb and innovate leapfrog technologies.
Pharmacological Characterization of Human and Murine Neuropeptide S Receptor Variants

We have recently shown that Neuropeptide S (NPS) can promote arousal and induce anxiolytic-like effects after central administration in rodents. Another study reported a number of natural polymorphisms in the human NPS receptor gene. Some of these polymorphisms were associated with increased risk of asthma and possibly other forms of atopic diseases, but the physiological consequences of the mutations remain unclear. One of the polymorphisms produces an Asn-Ile exchange in the first extracellular loop of the receptor protein, and a C-terminal splice variant of the NPS receptor was found overexpressed in human asthmatic airway tissue. We sought to study the pharmacology of the human receptor variants in comparison with the murine receptor protein. Here, we report that the N107I polymorphism in the human NPS receptor results in a gain-of-function characterized by an increase in agonist potency without changing binding affinity in NPSR Ile107. In contrast, the C-terminal splice variant of the human NPS receptor shows a pharmacological profile similar to NPSR Asn107. The mouse NPS receptor, which also carries an Ile residue at position 107, displays an intermediate pharmacological profile. Structure-activity relationship studies show that the amino terminus of NPS is critical for receptor activation. The altered pharmacology of the Ile107 isoform of the human NPS receptor implies a mechanism of enhanced NPS signaling that might have physiological significance for brain function as well as peripheral tissues that express NPS receptors.
Testing and Assessing English Word-Formation

Abstract The paper discusses the testing/assessment of word-formation skills in thresholdlevel (B1) learners. To determine the suitability and use of productive gap-fill exercises at this level, an example of a word-formation exercise is addressed from the following perspectives: word frequency (corpus data), morphological complexity (morpheme types and wordformation processes), syntactic environments (typical sentence and/or phrase patterns), analysis of statistical data (facility values) and test-takers’ errors. The text also addresses some implications of the findings for the instruction of lexis.
Phosphorylated human tau associates with mouse prion protein amyloid in scrapie-infected mice but does not increase progression of clinical disease

ABSTRACT Tauopathies are a family of neurodegenerative diseases in which fibrils of human hyperphosphorylated tau (P-tau) are believed to cause neuropathology. In Alzheimer disease, P-tau associates with A-beta amyloid and contributes to disease pathogenesis. In familial human prion diseases and variant CJD, P-tau often co-associates with prion protein amyloid, and might also accelerate disease progression. To test this latter possibility, here we compared progression of amyloid prion disease in vivo after scrapie infection of mice with and without expression of human tau. The mice used expressed both anchorless prion protein (PrP) and membrane-anchored PrP, that generate disease associated amyloid and non-amyloid PrP (PrPSc) after scrapie infection. Human P-tau induced by scrapie infection was only rarely associated with non-amyloid PrPSc, but abundant human P-tau was detected at extracellular, perivascular and axonal deposits associated with amyloid PrPSc. This pathology was quite similar to that seen in familial prion diseases. However, association of human and mouse P-tau with amyloid PrPSc did not diminish survival time following prion infection in these mice. By analogy, human P-tau may not affect prion disease progression in humans. Alternatively, these results might be due to other factors, including rapidity of disease, blocking effects by mouse tau, or low toxicity of human P-tau in this model.
Health status and health care services in Uttar Pradesh and Bihar: a comparative study.

BACKGROUND India's growth hype and dream of emerging as an economic superpower are being challenged today, among other things, by its failure to foster an inclusive growth path and provide to bulk of its population basic amenities of education and health. There exists great inequality at interstate and intrastate level in terms of the key components of human development-health and education. AIMS The present work attempts to measure the extent of the inequality in health status and health care services in the two most populous states of India namely Uttar Pradesh and Bihar. MATERIALS AND METHODS A detailed analysis of interdistrict and interregion disparity in health status and health care in the two states has been done using secondary data from Annual Health Survey (2011) and Statistical Diary (2011). Composite indices of health status and health services have been developed using Maher's normalization technique and principal component analysis. Inequality measures like co-efficient of variations have been used to measure the relevant disparities in the two states and explain the reason thereof. RESULTS The work shows low overall health status and wide interdistrict and interregion health disparity in the two states with lower disparity in Uttar Pradesh as compared to Bihar in terms of health status and relatively high disparity in health infrastructure. One startling fact is existence of very low and insignificant correlation between infrastructure and outcome. CONCLUSION The study finds health status is influenced not only by health care facilities, but a number of other factors principally government's commitment and policies.
The expression of Conceptual Syntagmatic Relationships: a Comparative Survey

The expression of conceptual syntagmatic relationships in document retrieval systems holds out hope for both increased discrimination (generally) and increased recall (in certain contexts). The inclusion of such relationships in retrieval systems requires both a structured inventory of relationships and some means of expressing them; this article examines the latter. To be fully effective, the expression of conceptual syntagmatic relationships must comply with criteria of systematicity, complexity, efficiency and naturalness. Unfortunately, the complex interaction of natural language means of expressing these relationships (lexicalisation, word order, function words and morphosyntactic cases) causes them to fail the systematicity criterion. Most document retrieval system means of expressing conceptual syntagmatic relationships (as exemplified by various term co‐occurrence techniques, links and role indicators) fail to comply with this and other of the criteria. Only gestalt structures simultaneously representing relationships, participants and roles (for example, frames) conform fully to the criterial checklist.
Second-Order HMM-Based Diagnosis Method for Web Service Fault

Web service application is becoming a popular and important software application on the web. With the advent of more and more service application using on the web, it is a crucial challenge to use an effective diagnostic technology to localize the service faults. To improve the diagnosis capability for service application software, we build a second-order hidden Markov diagnosis model by considering the dependency relationship of three ordered behaviors in the service process. Furthermore, we extend the Viterbi algorithm to find the most likelihood correct behavior sequence with the exception trace using the second-order HMM we propose. Finally, we compare the correct sequence with the exception one to localize the service faults. Experimental results show that our method is effective to the web service application in the fault diagnosis.
Natural sesquiterpenes β-caryophyllene and β-caryophyllene oxide as chemopreventive agents for cholangiocarcinoma

Cholangiocarcinoma (CCA) represents a particular type of liver cancer originating from the epithelial cells lining the intrahepatic and extrahepatic biliary tree. It is often clinically silent until it becomes an advanced disease with obstructive symptoms and a poor prognosis for patients [1]. In this context, searching for alternative therapeutic strategies becomes a pivotal goal in the battle against liver cancer. In present research, β-caryophyllene (CRY) and β-caryophyllene oxide (CRYO), two natural sesquiterpenes with protective properties [2], have been investigated for their ability to inhibit the growth of the human Mz-ChA-1 cholangiocarcinoma cells from extrahepatic bile ducts and the H69 non-malignant cholagiocytes. The cells were exposed to the test compounds for 24 h, then the cytotoxicity was measured by MTT assay [3]; doxorubicin was included as a standard cytotoxic agents. Both sesquiterpenes reduced the cholangiocytes proliferation. Particularly, CRY produced a marked cytotoxicity in the Mz-ChA-1cells at concentrations lower than that required for CRYO. Surprisingly, the antiproliferative effects produced by both CRY and CRYO were higher than that of the standard doxoru- bicin. In the non-malignant cholangiocytes, in spite of a low cytotoxicity of CRYO, CRY reduced the cell proliferation already at lower concentrations, acting in a similar way to doxorubicin. Being CRYO an epoxide analogue of CRY, the different cytotoxicity found could be due to their structural features and bioavailability. Present results encourage further studies on CRY and CRYO as chemopreventive agents for cholangiocarcinoma. This work was supported by grants from Sapienza University Project 2014. Dr. Antonella Di Sotto was financed by “Enrico and Enrica Sovena” Foundation.