Miracle-dz/UniFAR-FTUs huggingface dataset:
Affect TPB: A Model to Predict Knowledge Sharing Behaviour by considering Affect, Social Communication Behaviour, and Social Collaboration Behaviour

Many Web 2.0 interactive online sites have grown at an alarming rate and they have changed the communication and collaboration behavior of knowledge workers in knowledge driven organizations. Social networking sites are online platforms that allow people to collaborate and communicate through a variety of services (Broughton, Higgins, Hicks & Cox, 2009). These social networking sites drive new forms of social interaction, allowing users to intermingle and cooperate with each other by exchanging ideas by posting updates and comments. It is crucial to comprehend how social relationships affect the content shared among knowledge workers in virtual worlds. Lately many social network features were introduced based on some feedbacks found by researchers in the area of affective computing. Since affect is a thorny and cryptic area of research in psychology field, it is unidentified whether the knowledge sharing activity and the affect are closely related in the Information Systems research (Russell, 2003). Hence this research investigates the relationships of positive and negative affect and knowledge sharing attitude among knowledge workers in organization. Furthermore, the influence of social communication and social collaboration behaviuor on knowledge sharing behaviour will also be analyzed in the proposed Affect TPB Model.
Late Entry into HIV Care: Estimated Impact on AIDS Mortality Rates in Brazil, 2003–2006

Background Worldwide, a high proportion of HIV-infected individuals enter into HIV care late. Here, our objective was to estimate the impact that late entry into HIV care has had on AIDS mortality rates in Brazil. Methodology/Principal Findings We analyzed data from information systems regarding HIV-infected adults who sought treatment at public health care facilities in Brazil from 2003 to 2006. We initially estimated the prevalence of late entry into HIV care, as well as the probability of death in the first 12 months, the percentage of the risk of death attributable to late entry, and the number of avoidable deaths. We subsequently adjusted the annual AIDS mortality rate by excluding such deaths. Of the 115,369 patients evaluated, 50,358 (43.6%) had entered HIV care late, and 18,002 died in the first 12 months, representing a 16.5% probability of death in the first 12 months (95% CI: 16.3–16.7). By comparing patients who entered HIV care late with those who gained timely access, we found that the risk ratio for death was 49.5 (95% CI: 45.1–54.2). The percentage of the risk of death attributable to late entry was 95.5%, translating to 17,189 potentially avoidable deaths. Averting those deaths would have lowered the 2003–2006 AIDS mortality rate by 39.5%. Including asymptomatic patients with CD4+ T cell counts >200 and ≤350 cells/mm3 in the group who entered HIV care late increased this proportion by 1.8%. Conclusions/Significance In Brazil, antiretroviral drugs reduced AIDS mortality by 43%. Timely entry would reduce that rate by a similar proportion, as well as resulting in a 45.2% increase in the effectiveness of the program for HIV care. The World Health Organization recommendation that asymptomatic patients with CD4+ T cell counts ≤350 cells/mm3 be treated would not have a significant impact on this scenario.
MiF: Mitigating the Intra-file Fragmentation in Parallel File System

Parallel file systems have been broadly deployed in large scale data centers, supporting a wide range of applications across a variety of industries. Unfortunately, most parallel file systems suffer from the intra-file fragmentation which is the disk performance killer. This paper presents the design and implementation of MiF, which introduces two techniques: on-demand preallocation and embedded directory, to Mitigate theintra-file Fragmentation of data placement, improving the disk performance in parallel ï¬le system. The key insight of on-demand preallocation is that the preallocation of a ï¬le should be aware of concurrent process streams and recognizes the write characteristic. The background rationale of embedded directory is that, since modern parallel ï¬le systems aggregate many normal operation pairs, exploring the disk bandwidth for metadata access requires all metadata of sub-ï¬les in the same directory be placed adjacently. Measurements of our MiF implementation in a block-based parallel ï¬le system demonstrate that it can signiï¬cantly improve I/O performance of parallel programs.
Fuzzy set approximation using polar co-ordinates and linguistic term shifting

Fuzzy systems built on sparse rule bases apply special inference techniques. A large family of them can be described by the concept of the general methodology of the fuzzy rule interpolation (GM) [1]. Accordingly to this the conclusion is produced in two steps. First a new rule is interpolated corresponding to the position of the reference point of the observation in each antecedent dimension. Secondly the conclusion is determined by firing this rule. This paper proposes a novel set approximation method (FEAT-p) applicable in the first step of the GM for the determination of the antecedent and consequent sets of the new rule. The suggested technique introduces the concept of the polar cut and calculates the points of the shape of the sets taking into consideration all sets belonging to the actual partition. The method can handle subnormal sets, too.
Combinatorial Selection of RNA Ligands for Complex Cellular Targets

This study explores the selection of high affinity RNA ligands for the complex cellular targets present in crude HeLa nuclear extract through directed evolution and deconvolution. RNA ligands for the mixed nuclear targets were selected from around 6 × 1014 RNA sequences through an iterated enrichment process. RNA ligands for various gene products of the extract were simultaneously selected and were shown to specifically interact with their target molecules. The target molecules were isolated from the nuclear extract by affinity chromatography using columns tagged with the RNA ligands, resolved on two-dimensional gels, and identified by mass spectrometry. These RNA ligands may be useful in characterizing novel functions of cellular proteins and modulating complex molecular events.
Preparation and isolation of immunologically active glycopeptides from carcinoembryonic antigen (CEA)

In order to determine the structure of the tumor‐specific immunodominant group of the carcinoembryonic antigen (CEA) of human gastro‐intestinal tumors, immunologically active fragments from this glycoprotein were prepared by partial enzymatic hydrolysis using the proteolytic enzyme nagase. The fragments were purified by sequential molecular sieve, adsorption and ion exchange chromatography, and were analysed for carbohydrate and amino‐acid composition by gas‐liquid chromatography. The antigenic activity of each fragment was tested using both the Z‐gel and Farr radioimmunoassay techniques for CEA. Immunologically active glycopeptides with molecular weights of 1,000–5,000 Daltons, which contained the tumor antigenic determinant of CEA, had relatively high contents of N‐acetyl‐D‐glucosamine, aspartic acid or asparagine, and glutamic acid or glutamine.
Three dimensional MRI estimates of brain and spinal cord atrophy in multiple sclerosis

OBJECTIVE The association between brain atrophy and permanent functional deficits in multiple sclerosis and the temporal relation between atrophy and the clinical disease course have seldom been investigated. This study aims to determine the amount of infratentorial and supratentorial atrophy in patients by comparison with healthy controls, to establish the relation between atrophy and disability, and to derive the rates of volume loss in individual patients from their estimated disease durations. METHODS Three dimensional acquired MRI was performed on 20 relapsing-remitting and 20 secondary progressive multiple sclerosis patients and 10 control subjects. Volume data on infratentorial and supratentorial structures were obtained using the Cavalieri method of modern design stereology in combination with point counting. Corpus callosal sectional area and “T2 lesion load” were also determined. RESULTS Significantly reduced infratentorial and cerebral white matter volumes and corpus callosal sectional areas occurred in all patients compared with controls (p=0.0001–0.004). Mean estimates of volume loss in the cohort were −21%,−19%,−46%, and−12% for the brain stem, cerebellum, upper cervical cord and white matter, respectively, and −21% for the corpus callosal sectional area. Analysis of the amount of atrophy (volume differences between patients and controls) showed that upper cervical cord and cerebral white matter atrophy correlated with the expanded disability status scale (r=−0.37 and −0.37, p=0.018–0.023) and the Scripps neurologic rating scale scores (r=+0.49 and +0.43, p= 0.002–0.007). There was no relation between estimated volume loss in the supratentorial and infratentorial compartments. The “T2 lesion load” was associated with ventricular enlargement and corpus callosal atrophy (r=+0.50 and−0.55, p=0.0003–0.0012). Infratentorial atrophy rates correlated with baseline exacerbation rates (r=−0.50 to−0.48, p=0.0016–0.0021) and were higher in relapsing-remitting than secondary progressive patients (p=0.009–0.02). CONCLUSIONS Significant cerebral and spinal cord volume reductions occurred in both patient subgroups compared with controls. Functional correlates were found with estimated volume loss in the upper cervical cord and cerebral white matter. Particularly for infratentorial structures, estimated rates of atrophy were higher in relapsing-remitting than secondary progressive patients, suggesting that atrophy, perhaps mainly due to tract degeneration, begins early in multiple sclerosis and may relate predominantly to acute inflammatory events, with or without other gradual non-inflammatory processes later in the disease course.
COMSOL modeling of Hall sensors efficiency

In this paper we present a finite element analysis routine for modeling of semiconductor Hall sensors. Their efficiency is studied varying the base semiconductor material. More specifically, 2D COMSOL semi-conductor model is initially employed to extract the properties of the conductive channel. Subsequently a 3D COMSOL DC model is used to perform the studies regarding the Hall sensor efficiency. Hall sensors of identical topology and doping levels are studied in a comparative manner.
Prediction of lipoprotein signal peptides in Gram‐negative bacteria

A method to predict lipoprotein signal peptides in Gram‐negative Eubacteria, LipoP, has been developed. The hidden Markov model (HMM) was able to distinguish between lipoproteins (SPaseII‐cleaved proteins), SPaseI‐cleaved proteins, cytoplasmic proteins, and transmembrane proteins. This predictor was able to predict 96.8% of the lipoproteins correctly with only 0.3% false positives in a set of SPaseI‐cleaved, cytoplasmic, and transmembrane proteins. The results obtained were significantly better than those of previously developed methods. Even though Gram‐positive lipoprotein signal peptides differ from Gram‐negatives, the HMM was able to identify 92.9% of the lipoproteins included in a Gram‐positive test set. A genome search was carried out for 12 Gram‐negative genomes and one Gram‐positive genome. The results for Escherichia coli K12 were compared with new experimental data, and the predictions by the HMM agree well with the experimentally verified lipoproteins. A neural network‐based predictor was developed for comparison, and it gave very similar results. LipoP is available as a Web server at www.cbs. dtu.dk/services/LipoP/.
Emotion Recognition Pattern in Adolescent Boys with Attention-Deficit/Hyperactivity Disorder

Background. Social and emotional deficits were recently considered as inherent features of individuals with attention-deficit hyperactivity disorder (ADHD), but only sporadic literature data exist on emotion recognition in adolescents with ADHD. The aim of the present study was to establish emotion recognition profile in adolescent boys with ADHD in comparison with control adolescents. Methods. Forty-four adolescent boys (13–16 years) participated in the study after informed consent; 22 boys had a clinical diagnosis of ADHD, while data were also assessed from 22 adolescent control boys matched for age and Raven IQ. Parent- and self-reported behavioral characteristics were assessed by the means of the Strengths and Difficulties Questionnaire. The recognition of six basic emotions was evaluated by the “Facial Expressions of Emotion-Stimuli and Tests. ” Results. Compared to controls, adolescents with ADHD were more sensitive in the recognition of disgust and, worse in the recognition of fear and showed a tendency for impaired recognition of sadness. Hyperactivity measures showed an inverse correlation with fear recognition. Conclusion. Our data suggest that adolescent boys with ADHD have alterations in the recognition of specific emotions.
Pierre Robin sequence associated with first trimester fetal tamoxifen exposure

Tamoxifen is a nonsteroidal antiestrogen used as the current adjuvant endocrine treatment of choice for premenopausal women treated for breast cancer and its potential for causing fetal harm during pregnancy remains inconclusive. While the evidence of tamoxifen's effects on humans in utero is minimal, animal studies have shown evidence of teratogenicity, hence the FDA's class D categorization of the drug. In 1994 Cullins et al. published a case report entitled “Goldenhar's Syndrome Associated with Tamoxifen Given to the Mother During Gestation. ” At the time of publication, the authors noted that the manufacturer of tamoxifen knew of two cases associated with tamoxifen administration which resulted in congenital craniofacial defects. Cullins' case of Goldenhar syndrome is also a craniofacial disorder and thus represented the third such case. We report on the fourth case of a tamoxifen‐associated craniofacial anomaly. The mother became pregnant while undergoing tamoxifen therapy for breast cancer. A child with severe micrognathia and cleft palate was born. It is noteworthy that the two patterns of craniofacial malformations in tamoxifen exposed infants—Goldenhar syndrome in Cullins' et al. case and Pierre Robin sequence reported here—have also both been observed in isotretinoin exposed infants. While a larger spectrum of anomalies is characteristic of retinoic acid embryopathy, the specific craniofacial anomalies include facial asymmetry, microtia, micrognatha and U‐shaped cleft of the secondary palate, that is, malformations seen in the two tamoxifen exposed infants. Therefore, it is conceivable that these two agents could produce comparable embryotoxic effects if they function in a like way during embryogenesis. While the majority of tamoxifen exposed infants are normal, the ascertainment of teratogenic effects from tamoxifen will best be determined by data from teratogen registries. © 2008 Wiley‐Liss, Inc.
Video Streaming over HSDPA for Delivery of Essential Services in Under Serviced Areas in Africa

In the last decade, the growth in GDP across the African continent has been to a greater degree spurred by increased deployment and subscription to GSM and 3 G cellular networks. Poor or non-existent copper/fibre and mesh networks, largely inefficient telecommunications management and/or ineffective telecommunications policies in addition to poor infrastructure have made it nearly impossible to deliver essential services in health, education, trade and industry etc. In this paper, existing 3 G high-speed packet networks is evaluated as an alternative intervention to poor telecommunication infrastructure for the delivery of essential services such as telemedicine, emergency health services, tele-education and e-commerce in under-serviced areas. Simulation results show that HSDPA in target areas with rural, hilly and remote urban environments meet QoS parameters in terms of bit rates that are well above the minimum of 32 kbps for a H.263 codec target bit-rate of 16 kbps video quality. The envisioned capacity satisfies the QoS parameters for provision of essential services, if a distributed centralized approach is adopted. 3 G streaming can thus be used to deliver essential services in under-serviced areas.
Minimap: a web page visualization method for mobile phones

The Web has become available even on mobile phones, but the current methods to view large pages on small screens have not been highly usable. Current mobile phone browsers reformat Web pages to a single column that fits the screen width. Because not all content is comprehensible in this format, browsers provide a second mode for viewing pages in the same layout as on a PC. We have developed a modeless Web page visualization method called Minimap that shows pages in a modified Original layout. We conducted a long-term usability study with 20 participants to compare the state-of-the-art mobile phone browser with this new method. 18 participants preferred the new method, and it also scored better in more detailed usability ratings.
Preparation, characterization, and assessment of the antiglioma effects of liposomal celastrol

The role of celastrol in the treatment of cancer has been an area of growing interest. To circumvent the issues of low solubility, poor bioavailability, and systemic toxicity of celastrol, we prepared liposomal celastrol using the thin-film dispersion method. We characterized particle size, encapsulation efficiency, and pharmacological parameters of liposomal celastrol. The drug concentration in plasma and tissues was measured using LC-MS/MS. In addition, the sulforhodamine B assay was used to determine the 50% inhibiting concentration. We assessed the effects of the compound in SHG-44 glioma subcutaneous xenografts in BALB/c nude mice. To compare the toxic effects of liposomal and free celastrol, the weight as well as hematologic, heart, liver, and kidney parameters were measured weekly and the morphology of organ tissues was observed pathologically. We found that liposomal celastrol had high encapsulation efficiency (71.67%) and liposomal celastrol had a higher Cmax and area under the curve, longer t1/2, and better biodistribution than free celastrol. A cytotoxicity assay indicated that free celastrol had lower 50% inhibiting concentration values than the liposomal celastrol; however, treatment of subcutaneous xenografts with 1 mg/kg of liposomal celastrol induced greater antitumor activity than free celastrol at an equimolar concentration. In addition, a 4 mg/kg dose of liposomal celastrol had fewer severe side effects than free celastrol at the same dose. In this study, we found that the use of liposomes as a carrier of celastrol increased the bioavailability and reduced the side effects of the compound. Our findings suggest that liposomal celastrol should be further investigated in the clinical setting.
Testosterone, Plumage Colouration and Extra-Pair Paternity in Male North-American Barn Swallows

In most monogamous bird species, circulating testosterone concentration in males is elevated around the social female's fertile period. Variation in elevated testosterone concentrations among males may have a considerable impact on fitness. For example, testosterone implants enhance behaviours important for social and extra-pair mate choice. However, little is known about the relationship between natural male testosterone concentration and sexual selection. To investigate this relationship we measured testosterone concentration and sexual signals (ventral plumage colour and tail length), and determined within and extra-pair fertilization success in male North American barn swallows (Hirundo rustica erythrogaster). Dark rusty coloured males had higher testosterone concentrations than drab males. Extra-pair paternity was common (42% and 31% of young in 2009 and 2010, respectively), but neither within- nor extra-pair fertilization success was related to male testosterone concentration. Dark rusty males were less often cuckolded, but did not have higher extra-pair or total fertilization success than drab males. Tail length did not affect within- or extra-pair fertilization success. Our findings suggest that, in North American barn swallows, male testosterone concentration does not play a significant direct role in female mate choice and sexual selection. Possibly plumage colour co-varies with a male behavioural trait, such as aggressiveness, that reduces the chance of cuckoldry. This could also explain why dark males have higher testosterone concentrations than drab males.
High Speed, High Stability and Low Power Sensing Amplifier for MTJ/CMOS Hybrid Logic Circuits

Densely embedding Magnetic Tunnel Junctions (MTJ) in CMOS logic circuits is considered as one potentially powerful solution to bring non volatility, instant on/off and low standby power in today's programmable logic circuits, in order to overcome major drawbacks while preserving high operation speed. A critical issue in this process is the integration of MTJ electric signal to CMOS electronics, in particular the requirement of ldquozerordquo read/write error for logic applications. In this paper, we propose a new sense amplifier circuit, called Pre-Charge Sense Amplifier (PCSA). This circuit, comprising 7 CMOS transistors at minimum size, is able to read the magnetic configuration of a pair of magnetic tunnel junctions with opposite configurations at high speed (about 200 ps), with very low power and error rate compared to previously proposed solutions. Simulations using a ST Microelectronics 90 nm design kit and a compact model of MTJ demonstrate the performances of PCSA.
Leveraging Features and Networks for Probabilistic Tensor Decomposition

We present a probabilistic model for tensor decomposition where one or more tensor modes may have side-information about the mode entities in form of their features and/or their adjacency network. We consider a Bayesian approach based on the Canonical PARAFAC (CP) decomposition and enrich this single-layer decomposition approach with a two-layer decomposition. The second layer fits a factor model for each layer-one factor matrix and models the factor matrix via the mode entities' features and/or the network between the mode entities. The second-layer decomposition of each factor matrix also learns a binary latent representation for the entities of that mode, which can be useful in its own right. Our model can handle both continuous as well as binary tensor observations. Another appealing aspect of our model is the simplicity of the model inference, with easy-to-sample Gibbs updates. We demonstrate the results of our model on several benchmarks datasets, consisting of both real and binary tensors.
Cost-efficient universal approach for remote meter reading using web services and computer vision

The Internet of Things is a great vision but also an important challenge for the current research. Through, the connection of many different devices there are outstanding benefits such as an increasing automation and intelligent energy management. Nevertheless, the integration of legacy devices into the Internet of Things is a significant issue. Legacy meters, e.g., cannot provide metering data automatically and the installation of modern smart meters is cost-intensive and thus often unprofitable. An alternative approach is to extend legacy meters with an automatic meter reading system. Thus, they can be integrated into an intelligent system such as an efficient energy management. In this paper a robust and universal approach for automatic meter reading is proposed. The approach can be applied to water, gas, and electric meters and uses a Web service as standardized and open communication interface. The recognition rate of a prototype implementation is 98 % and the measurement duration is approx. 1.5 seconds. The entire system was implemented on a Raspberry Pi as a cost-efficient hardware platform.