Miracle-dz/UniFAR-FTUs huggingface dataset:
Antibodies to Escherichia coli Outer Membrane Porin C in the Absence of Anti–Saccharomyces cerevisiae Antibodies and Anti-neutrophil Cytoplasmic Antibodies Are an Unreliable Marker of Crohn Disease and Ulcerative Colitis

Objectives: Antibodies to Escherichia coli outer membrane porin C (anti-OmpC), Saccharomyces cerevisiae, and neutrophil-specific nuclear antigens are associated with inflammatory bowel disease (IBD) in children and young adults. We hypothesized that anti-OmpC, in the absence of anti–S cerevisiae antibodies (ASCA) and antineutrophil cytoplasmic antibodies (ANCA), is an assay that overestimates the presence of Crohn disease (CD) and ulcerative colitis (UC). Patients and Methods: A retrospective review of patients evaluated at our institution between January 2002 and June 2006 revealed that 170 had serodiagnostic immunological assays performed as part of an evaluation for possible IBD. The assays were screened for a pattern in which anti-OmpC was present in the absence of ASCA and ANCA. Results: Seven patients between 3 and 20 years of age were discovered to be positive for anti-OmpC but negative for ASCA and ANCA. These patients were determined to have significant medical conditions without combined radiographic, endoscopic, or histological evidence of IBD. Despite the reported 85% positive predictive value of anti-OmpC for IBD, none of the 7 patients with isolated anti-OmpC had a diagnosis of CD or UC. Conclusions: Anti-OmpC, in the absence of ASCA and ANCA, is a serological pattern noted in a subset of medically complex cases in children and young adults without CD or UC.
Compact low-loss monolithic CPW filters using air-gap overlay structures

In this letter, two types of compact low-loss monolithic coplanar waveguide (CPW) filters using air-gap overlay structures are presented. Vertical stacking in overlay structures offers size reduction. Furthermore, air-gap overlay structures do not require additional dielectric process and are free from dielectric losses. An X-band bandpass filter using air-gap overlaid artificial transmission lines showed 67% size reduction. A stepped-impedance low-pass filter using highly separated metal-air-metal (MAM) capacitors as low-impedance lines achieved not only size but also loss reduction. Small size, low loss, and simple process steps make the air-gap overlay structures very promising for monolithic CPW passive devices such as filters.
Intelligence or Misorientation? Eurocentrism in the WISC-III

Intelligence testing with children of African descent has a turbulent history. Cultural biases in test content, administration, and standardization procedures have resulted in inappropriate diagnostic classifications for many African American children. Yet, intelligence testing continues to enjoy widespread clinical practice, and the Wechsler Intelligence Scale for Children—Third Edition (WISC-III) is one of the most popular tests. This article examines the Eurocentric basis of the test and reveals the WISC-III’s antagonistic and incompatible relationship to an Africentric conception of intellectual and mental health.
When Touch Elicits Cold: Functional Imaging of an Abnormal Sensation

The authors report a 58‐year‐old man who presented with touch‐induced cold sensations and loss of pain and normal temperature sensation in the left leg and trunk. He was found to have syringomyelia at the level of the third thoracic vertebrae. A functional magnetic resonance imaging (fMRI) study was performed to evaluate the underlying cortical processing of the touch‐induced cold sensations. Blood oxygen level‐dependent(BOLD) responses were measured in response to light tonic pressure stimuli and to cold stimuli applied to both the symptomatic area on the left leg and to the unaffected contralateral side. Tonic pressure applied on the unaffected right thigh and the left hand resulted in activations of contralateral primary (S1) and bilateral secondary somatosensory cortices (S2). In contrast, application of tonic pressure to the affected left thigh, ie, where touch stimuli elicited cold sensations, induced robust activations not only in contralateral S1 and bilateral S2, but also in bilateral insular cortices, which are cortical areas known to be pivotally involved in the central processing of cold. The fMRI data argue in favor of supraspinal cross‐submodal plastic changes within the somatosensory system.
Deconstructing test anxiety

Recent changes to educational policy which have focused attention on the use of high stakes testing as performance and accountability measures have renewed interest in test anxiety both in the UK and the USA. The aim of this paper is to provide a critical examination of the test anxiety construct, and explore the ways in which test anxiety is written about and conceptualised in the existing literature. It is intended that this paper would provide a companion to the comprehensive reviews that already exist, to provoke scholarly thought and debate around the existing literature, than to provide an additional review. Discussion is based around five themes: (1) how test anxiety is differentiated from the anxiety construct in general; (2) the differing conceptions of test anxiety in the literature; (3) the relationship between test anxiety and other, related constructs; (4) how measurement concerns have driven development of the test anxiety construct; and (5) the focus on worry and performance deficits leading to definitional problems. Two directions for future work are highlighted: first, to continue the exploration of test anxiety with other related constructs; and second, to develop qualitative approaches to the study of test anxiety.
Role of Calcium Cycling Versus Restitution in the Mechanism of Repolarization Alternans

Abstract— T-wave alternans, a powerful marker of arrhythmic events, results from alternation in action potential duration (APD). The underlying cellular mechanism of APD alternans is unknown but has been attributed to either intracellular calcium (Ca2+) cycling or membrane ionic currents, manifested by a steep slope of cellular APD restitution. To address these mechanisms, high-resolution optical mapping techniques were used to measure action potentials and Ca2+ transients simultaneously from hundreds of epicardial sites in the guinea pig model of pacing-induced T-wave alternans (n=7). The pacing rates (ie, alternans threshold) at which T-wave (369±11 bpm), APD (369±21 bpm), and Ca2+ (371±29 bpm) alternans first appeared were comparable. Importantly, the site of origin of APD alternans and Ca2+ alternans consistently occurred together near the base of the left ventricle, not where APD restitution was steepest. In addition, APD and Ca2+ alternans were remarkably similar both spatially and temporally during discordant alternans. In conclusion, the mechanism underlying T-wave alternans in the intact heart is more closely associated with intracellular Ca2+ cycling rather than APD restitution.
Optimization of the expression of recombinant human activin A in the yeast Pichia pastoris

We report a new procedure to express recombinant human activin A using the methanolic yeast, Pichia pastoris. Optimization of culture procedures has involved comprehensive examination of the effects of culture vessel shape, volume of broth in the induction and expression cultures, methanol concentration, culturing temperature, and pH of the expression cultures. After this optimization, as well as modification of the native cleavage sites, a laboratory scale procedure has been established which routinely produced 2–10 mg/L amounts of this vital growth factor in the highly efficient, eukaryotic yeast system. This system avoids the need to produce this protein and similar TGF‐β proteins in mammalian cell lines which, in addition to being costly, produce many native binding partners of these cystine knot proteins, a factor which can dramatically affect yields of the target protein. © 2010 American Institute of Chemical Engineers Biotechnol. Prog. , 2010
Using Food Ethnographies to Promote Systems Thinking and Intergenerational Engagement among College Undergraduates

Abstract This article discusses an intergenerational, interdisciplinary service-learning project that integrated courses on life-cycle nutrition and developmental psychology. Students from the two classes worked in teams to interview older adult learning partners in their community about diet, lifestyle, and personal life events deemed relevant to nutrition and wellbeing, to create food ethnographies based on information learned. As a service-learning component, students provided the older adults with individualized nutrition and wellness plans at the end of the project, based on the older adult's expressed interests and concerns. In this paper, we describe how the project was carried out; discuss how learning goals pertaining to systems thinking, sustainability consciousness, and intergenerational engagement were assessed; and present the results of that assessment. Results of qualitative analyses of student work, as well as quantitative analyses of a course survey indicate that the project facilitated student learning related to the three goals.
Improving Associative Memory Capacity: One-Shot Learning in Multilayer Hopfield Networks

Our brains have an extraordinarily large capacity to store and recognize complex patterns after only one or a very few exposures to each item. Existing computational learning algorithms fall short of accounting for these properties of human memory; they either require a great many learning iterations, or the y can do one-shot learning but suffer from very poor capacity. In this paper, we explore one approach to improving the capacity of simple Hebbian pattern associators: adding hidden units. We propose a deterministic algorithm for choosing good target states for the hidden layer. In assessing performance of the model, we argue that it is critical to examine both increased stability and increased basin size of the attractor around each stored pattern. Our algorithm achieves both, thereby improving the network’s capacity to recall noisy patterns. Furthe r, the hidden layer helps to cushion the network from interference effects as the memory is overloaded. Another technique, almost as effective, is to “soft-clamp” the input layer duri ng retrieval. Finally, we discuss other approaches to improvi ng memory capacity, as well the relation between our model and extant models of the hippocampal system.
Target Tracking Using SePDAF under Ambiguous Angles for Distributed Array Radar

Distributed array radar can improve radar detection capability and measurement accuracy. However, it will suffer cyclic ambiguity in its angle estimates according to the spatial Nyquist sampling theorem since the large sparse array is undersampling. Consequently, the state estimation accuracy and track validity probability degrades when the ambiguous angles are directly used for target tracking. This paper proposes a second probability data association filter (SePDAF)-based tracking method for distributed array radar. Firstly, the target motion model and radar measurement model is built. Secondly, the fusion result of each radar’s estimation is employed to the extended Kalman filter (EKF) to finish the first filtering. Thirdly, taking this result as prior knowledge, and associating with the array-processed ambiguous angles, the SePDAF is applied to accomplish the second filtering, and then achieving a high accuracy and stable trajectory with relatively low computational complexity. Moreover, the azimuth filtering accuracy will be promoted dramatically and the position filtering accuracy will also improve. Finally, simulations illustrate the effectiveness of the proposed method.
Self-discrepancy theory as a framework for understanding bulimic symptomatology and associated distress.

This study explored the utility of self-discrepancy theory for understanding bulimic symptomatology and associated negative affect. Female undergraduates (n = 76) completed measures of self-discrepancy and bulimic symptoms and, one month later, completed depression and anxiety measures. As hypothesized, actual:ideal discrepancy was associated uniquely with bulimic symptomatology, but only in the realm of appearance-related attributes. Although neither actual:ideal nor actual:ought general discrepancies from the self standpoint were related to bulimia, discrepancies from the mother standpoint significantly predicted bulimic behaviors
Smart and secure IOT based child behaviour and health monitoring system using hadoop

— IoT is becoming very relevant and getting popular in the field of medical diagnosis nowadays. In this paper, we are bound to limelight in this field which focuses briefly over the child health monitoring. In this work, we implemented a smart and secure health care monitor application that personify the monitoring of total health and mind status of the children. As part of which we are adopting the use of wireless sensors that will keep the child to get monitored. Our system enables the child to get involved with some android games which will make him/her to think and act dynamically. The game scores and the sensor readings obtained from the child will be monitored and analyzed by the system and actions will be taken accordingly. Since the data generated by the system are humongous, we adopt Hadoop in the background to effectively map the data and to reduce it into elementary. As this data need confidentiality in transmission, Apache Ranger is being used for the secure transmission and for the classification of the child behavior, C4.5 decision algorithm is used in the system. While testing with the medical dataset, C4.5 proved to be more accurate than ID3 algorithm.
Accountability logic for mobile payment protocols

Accountability is one of the most important security properties of electronic commerce (e-commerce) protocols. It can be used to resolve disputes among involved parties. Several formal logics were proposed to analyze this property. However, they lack of reasoning about the accountability of symmetric cryptography which is necessary for analyzing mobile payment protocols. In this paper, we propose an extension of existing accountability logics which is capable to deal with both symmetric and asymmetric cryptographic messages. Moreover, we show that our logic is general in that party's requirements for payment transactions which are considered as goals of a payment protocol can be formalized by our logic.
Modernity and Self-Identity: Self and Society in the Late Modern Age

Acknowledgements Introduction 1. The contours of high modernity 2. The self: ontological security and existential anxiety 3. The trajectory of the self 4. Fate, risk, and security 5. The sequestration of experience 6. Tribulations of the self 7. The emergence of life politics Notes Glossary of concepts Index.
Early versus delayed percutaneous coronary intervention for patients with non‐ST segment elevation acute coronary syndrome: A meta‐analysis of randomized controlled clinical trials

Background: Studies assessing the timing of percutaneous coronary interventions (PCI) in patients with Non‐ST segment elevation Acute Coronary Syndromes (NSTE‐ACS) have failed to generate a consensus on how early PCI should be performed in such patients. Purpose: This meta‐analysis compares clinical outcomes at 30 days in NSTE‐ACS patients undergoing PCI within 24 hours of presentation (early PCI) with those receiving PCI more than 24 hours after presentation (delayed PCI). Data Sources: Data were extracted from searches of MEDLINE (1990‐2010) and Google scholar and from scrutiny of abstract booklets from major cardiology meetings (1990‐2010). Study selection: Randomized clinical trials (RCTs) that included the composite endpoint of death and non‐fatal myocardial infarction (MI) at 30 days after PCI were considered. Data Extraction: Two independent reviewers extracted data using standard forms. The effects of early and delayed PCI were analyzed by calculating pooled estimates for death, non‐fatal MI, bleeding, repeat revascularization and the composite endpoint of death or non‐fatal MI at 30 days. Univariate analysis of each of these variables was used to create odds ratios. Data Synthesis: Seven studies with a total of 13,762 patients met the inclusion criteria. There was no significant difference in the odds of the composite endpoint of death or non‐fatal MI at 30 days between patients undergoing early PCI and those receiving delayed PCI (OR‐0.83, 95%CI 0.62‐1.10). Patients receiving delayed PCI experienced a 33% reduction in the odds of repeat revascularization at 30 days compared to those undergoing early PCI (OR‐1.33, 95%CI 1.14‐1.56, P=0.0004). Conversely, patients undergoing early PCI experienced lower odds of bleeding than those receiving delayed PCI (OR‐0.76, 95%CI 0.63‐0.91, P = 0.0003). Conclusions: In NSTE‐ACS patients early PCI doesn't reduce the odds of the composite endpoint of death or non‐fatal MI at 30 day. This strategy is associated with lower odds of bleeding and higher odds of repeat revascularization at 30 days than a strategy of delayed PCI. © 2012 Wiley Periodicals, Inc.
An Efficient Trust Mechanism in P2P Network

With the proliferation of P2P application, it is critical to consider how these systems can be run in a trust environment. We present a lightweight time-window based effective dynamic trust mechanism(Tw-Trust) considering the peer’s local and global trustworthiness. Simulation results show that Tw-Trust has the advantages in countering strategic altering behavior and dishonest feedbacks of malicious peers.
Symbolic execution of stored procedures in database management systems

Stored procedures in database management systems are often used to implement complex business logic. Correctness of these procedures is critical for correct working of the system. However, testing them remains difficult due to many possible states of data and database constraints. This leads to mostly manual testing. Newer tools offer automated execution for unit testing of stored procedures but the test cases are still written manually. In this paper, we propose a novel approach of using dynamic symbolic execution to automatically generate test cases and corresponding database states for stored procedures. We treat values in database tables as symbolic, model the constraints on data imposed by the schema and by the SQL statements executed by the stored procedure. We use an SMT solver to find values that will drive the stored procedure on a particular execution path. We instrument the internal execution plans generated by PostgreSQL database management system to extract constraints and use the Z3 SMT solver to generate test cases consisting of table data and procedure inputs. Our evaluation using stored procedures from a large business application shows that this technique can uncover bugs that lead to schema constraint violations and user defined exceptions.
Students improve patient care and prepare for professional practice: An interprofessional community-based study

Abstract Background: We report on an education model that enables students to contribute to practice while experiencing the realities of complex team-working in the community. Aims: The study considers how interprofessional learning impacts on patient care and service delivery. Method: A qualitative study using a realist approach. The views of practice-staff, patients and facilitators on how student team learning impacted on practice was obtained through focus groups, interviews and an e-questionnaire and compared to student analysis as feedback forms. Results: Staff from six Primary Health Care Teams (n = 23) stated that the student teams had offered solutions to improve the quality of patient care and on organisational systems. The positive value of the student work was confirmed by the course facilitators (n = 8). In addition, practitioners were propelled to maintain high professional standards. Patients (n = 23) recalled benefits directly attributable to the student work confirmed by the 434 student feedback forms. Conclusion: Undergraduate interprofessional student teams in mid-training can support and help practice teams, and this subsequently benefits patient care. This practice-based interprofessional learning model offers learning, which is theory-based, and supports positive student contributions. This learning fits today’s requirements for positive outcomes from education when mapped against the Kirkpatrick or the NHS (UK) education outcomes framework.
Parent-Offspring Transmission of Adipocytokine Levels and Their Associations with Metabolic Traits

Adipose tissue secreted cytokines (adipocytokines) have significant effects on the physiology and pathology of human metabolism relevant to diabetes and cardiovascular disease. We determined the relationship of the pattern of these circulating hormones with obesity-related phenotypes and whether such pattern is transmitted from parent to offspring. A combined total of 403 individuals from 156 consenting Saudi families divided into initial (119 families with 123 adults and 131 children) and replication (37 families with 58 adults and 91 children) cohorts were randomly selected from the RIYADH Cohort study. Anthropometrics were evaluated and metabolic measures such as fasting serum glucose, lipid profiles, insulin, leptin, adiponectin, resistin, tumor necrosis factor alpha (TNFα), activated plasminogen activator inhibitor 1 (aPAI1), high sensitivity C-reactive protein (hsCRP) and angiotensin II were also assessed. Parent-offspring regressions revealed that with the exception of hsCRP, all hormones measured showed evidence for significant inheritance. Principal component (PC) analysis of standardized hormone levels demonstrated surprising heritability of the three most common axes of variation. PC1, which explained 21% of the variation, was most strongly loaded on levels of leptin, TNFα, insulin, and aPAI1, and inversely with adiponectin. It was significantly associated with body mass index (BMI) and phenotypically stronger in children, and showed a heritability of ∼50%, after adjustment for age, gender and generational effects. We conclude that adipocytokines are highly heritable and their pattern of co-variation significantly influences BMI as early as the pre-teen years. Investigation at the genomic scale is required to determine the variants affecting the regulation of the hormones studied.
Tweets Mining: Knowledge from the SocialWeb

In the recent years, Social web mining has gained significant attention with case of it‟s an interactive platform via which individual of communities creates and shows user generated content and set of social relations that link people through the world wide web. Social Media becoming most powerful tool for information exchange has not only consumed information but also share and discusses information about aspects of their interest. Information retrieval and Text Mining have gained greater momentum in the recent past. Hence there is a need to mine the social media and generate useful knowledge based on identify interesting pattern from the user. The advantage of social media is the freedom of expressing their thoughts in text without following traditional language grammar‟s eventually this becomes the challenge for mining the social media. Moreover the volume of information is too huge and dynamic. The objective of this proposed work is to mine the social media, in our case twitter. The challenge involved is to understanding the user behavior and generating grammar rules pertaining to the tweet‟s language we also need to place the proximity of grammar used. The contribution of our work providing information retrieval tools with visual support. By applying the proposed algorithm, a study can be made on user behavior (Tweeters), fact analysis on the context of tweet and to identify the effective tweeters.