Miracle-dz/UniFAR-FTUs huggingface dataset:
Evaluation of the ruminal function of Belgian dairy cows suspected of subacute ruminal acidosis.

Subacute ruminal acidosis (SARA) has been considered a major pathology in high producing dairy herds for years. These findings were corroborated by several studies in Europe. However, different feeding practices and herds’ production levels are found in Southern Belgium. This study aimed to ascertain whether dairy cows of several herds from the south of Belgium (Wallonia) with a suspicion of SARA really did present too low ruminal pH values. Twenty-four herds were visited and 172 cows were sampled using an oropharyngeal device to collect ruminal fluid, i.e. Geishauser probe. On the samples, three tests were performed: pH measurement, methylene blue reduction test and microscopic evaluation of protozoa vitality. Based on these analyses, no cows demonstrated pH values lower than 5.5 and, only ten cows could be considered at risk for SARA. By contrast, in eightteen cows, pH values higher than 7.0 were measured and ruminal inactivity was suspected. In this study, ruminal alkalosis appeared to be more frequently observed than SARA.
Hybridizing relieff, mRMR filters and GA wrapper approaches for gene selection

Gene expression data comprises a huge number of genes but have only few samples that can be used to address supervised classification problems. This paper is aimed at identifying a small set of genes, to efficiently distinguish various types of biological sample; hence we have proposed a three-stage of gene selection algorithm for genomic data. The proposed approach combines ReliefF, mRMR (Minimum Redundancy Maximum Relevance) and GA (Genetic Algorithm) coded as (R-m-GA). In the first stage, the candidate gene set is identified by applying the ReliefF. While, the second minimizes the redundancy with the help of mRMR method, which facilitates the selection of effectual gene subset from the candidate set. In the third stage, GA with classifier (used as a fitness function by the GA) is applied to choose the most discriminating genes. The proposed method is validated on the tumor datasets such as: CNS, DLBCL and Prostate cancer, using IB1 classifier. The comparative analysis of the R-m-GA against GA and ReliefF-GA has revealed that the proposed method is capable of finding the smallest gene subset that offers the highest classification accuracy.
CLASSIFICATION ALGORITHMS FOR BIG DATA ANALYSIS, A MAP REDUCE APPROACH

Abstract. Since many years ago, the scientific community is concerned about how to increase the accuracy of different classification methods, and major achievements have been made so far. Besides this issue, the increasing amount of data that is being generated every day by remote sensors raises more challenges to be overcome. In this work, a tool within the scope of InterIMAGE Cloud Platform (ICP), which is an open-source, distributed framework for automatic image interpretation, is presented. The tool, named ICP: Data Mining Package, is able to perform supervised classification procedures on huge amounts of data, usually referred as big data, on a distributed infrastructure using Hadoop MapReduce. The tool has four classification algorithms implemented, taken from WEKA’s machine learning library, namely: Decision Trees, Naïve Bayes, Random Forest and Support Vector Machines (SVM). The results of an experimental analysis using a SVM classifier on data sets of different sizes for different cluster configurations demonstrates the potential of the tool, as well as aspects that affect its performance.
Glycine-rich RNA-binding proteins are functionally conserved in Arabidopsis thaliana and Oryza sativa during cold adaptation process

Contrary to the increasing amount of knowledge regarding the functional roles of glycine-rich RNA-binding proteins (GRPs) in Arabidopsis thaliana in stress responses, the physiological functions of GRPs in rice (Oryza sativa) currently remain largely unknown. In this study, the functional roles of six OsGRPs from rice on the growth of E. coli and plants under cold or freezing stress conditions have been evaluated. Among the six OsGRPs investigated, OsGRP1, OsGRP4, and OsGRP6 were shown to have the ability to complement cold-sensitive BX04 E. coli mutant cells under low temperature conditions, and this complementation ability was correlated closely with their DNA- and RNA-melting abilities. Moreover, OsGRP1 and OsGRP4 rescued the growth-defect of a cold-sensitive Arabidopsis grp7 mutant plant under cold and freezing stress, and OsGRP6 conferred freezing tolerance in the grp7 mutant plant, in which the expression of AtGRP7 was suppressed and is sensitive to cold and freezing stresses. OsGRP4 and OsGRP6 complemented the defect in mRNA export from the nucleus to the cytoplasm in grp7 mutants during cold stress. Considering that AtGRP7 confers freezing tolerance in plants and harbours RNA chaperone activity during the cold adaptation process, the results of the present study provide evidence that GRPs in rice and Arabidopsis are functionally conserved, and also suggest that GRPs perform a function as RNA chaperones during the cold adaptation process in monocotyledonous plants, as well as in dicotyledonous plants.
A Closer Look on Protein Unfolding Simulations through Hierarchical Clustering

Understanding protein folding and unfolding mechanisms are a central problem in molecular biology. Data obtained from molecular dynamics unfolding simulations may provide valuable insights for a better understanding of these mechanisms. Here, we propose the application of an augmented version of hierarchical clustering analysis to detect clusters of amino-acid residues with similar behavior in protein unfolding simulations. These clusters hold similar global pattern behavior of solvent accessible surface area (SASA) variation in unfolding simulations of the protein transthyretin (TTR). Classical hierarchical clustering was applied to build a dendrogram based on the SASA variation of each amino-acid residue. The dendrogram was enriched with background information on the amino-acid residues, enabling the extraction of sub-clusters with well differentiated characteristics
Sex Determination in the Monoecious Species Cucumber Is Confined to Specific Floral Whorls

In unisexual flowers, sex is determined by the selective repression of growth or the abortion of either male or female reproductive organs. The mechanism by which this process is controlled in plants is still poorly understood. Because it is known that the identity of reproductive organs in plants is controlled by homeotic genes belonging to the MADS box gene family, we analyzed floral homeotic mutants from cucumber, a species that bears both male and female flowers on the same individual. To study the characteristics of sex determination in more detail, we produced mutants similar to class A and C homeotic mutants from well-characterized hermaphrodite species such as Arabidopsis by ectopically expressing and suppressing the cucumber gene CUCUMBER MADS1 (CUM1). The cucumber mutant green petals (gp) corresponds to the previously characterized B mutants from several species and appeared to be caused by a deletion of 15 amino acid residues in the coding region of the class B MADS box gene CUM26. These homeotic mutants reveal two important concepts that govern sex determination in cucumber. First, the arrest of either male or female organ development is dependent on their positions in the flower and is not associated with their sexual identity. Second, the data presented here strongly suggest that the class C homeotic function is required for the position-dependent arrest of reproductive organs.
Natural variation for seed dormancy in Arabidopsis is regulated by additive genetic and molecular pathways

Timing of germination is presumably under strong natural selection as it determines the environmental conditions in which a plant germinates and initiates its postembryonic life cycle. To investigate how seed dormancy is controlled, quantitative trait loci (QTL) analyses has been performed in six Arabidopsis thaliana recombinant inbred line populations by analyzing them simultaneously using a mixed model QTL approach. The recombinant inbred line populations were derived from crosses between the reference accession Landsberg erecta (Ler) and accessions from different world regions. In total, 11 delay of germination (DOG) QTL have been identified, and nine of them have been confirmed by near isogenic lines (NILs). The absence of strong epistatic interactions between the different DOG loci suggests that they affect dormancy mainly by distinct genetic pathways. This was confirmed by analyzing the transcriptome of freshly harvested dry seeds of five different DOG NILs. All five DOG NILs showed discernible and different expression patterns compared with the expression of their genetic background Ler. The genes identified in the different DOG NILs represent largely different gene ontology profiles. It is proposed that natural variation for seed dormancy in Arabidopsis is mainly controlled by different additive genetic and molecular pathways rather than epistatic interactions, indicating the involvement of several independent pathways.
Re-considering female sexual desire: Internalized representations of parental relationships and sexual self-concept in women with inhibited and heightened sexual desire

RE-CONSIDERING FEMALE SEXUAL DESIRE: INTERNALIZED REPRESENTATIONS OF PARENTAL RELATIONSHIPS AND SEXUAL SELF-CONCEPT IN WOMEN WITH INHIBITED AND HEIGHTENED SEXUAL DESIRE by Eugenia Cherkasskaya Adviser: Margaret Rosario, Ph.D. Background: Psychoanalytic and sociocultural thinkers and researchers suggest that the etiology of low female sexual desire, the most prevalent sexual complaint in women, is multi-determined, implicating biological and psychological factors, including women’s early relational experiences and sexual self-concept that stem from gender dynamics of a patriarchal culture. Further, recent studies indicate that highly sexual women exhibit heightened sexual desire, and high levels of sexual agency and sexual esteem. The study evaluated a model that hypothesized that sexual self-concept (sexual subjectivity, self-objectification, genital self-image) explains (i.e., mediates) the relations between internalized representations of parental relationships (attachment, separation/individuation, parental identification) and sexual desire in heterosexual women. Methods: Six hundred participants completed self-report questionnaires, assessing the abovementioned variables. Subsequently, 20 women (10 with inhibited desire, 10 with heightened desire) were individually interviewed about their experiences of sexual desire to examine the differences in the phenomenology of female sexual desire between highly sexual and sexually inhibited women. Results: The results partially supported the hypotheses: internalized
Semantic Segmentation of Music audio Contents

ABSTRACT This paper proposes a novel approach to detect structural changes in music audio signals and provides a way to separate the different “sections” of a piece, i.e. “intro”, “verse” or “chorus”. Herein, we divide the segment boundaries detection task into a two-phase process with each having different functionalities. In order to obtain appropriate structural boundaries, we propose a combination of low-level descriptors to be extracted from music audio signals. A database of 54 audio files (The Beatles’ songs) is used for evaluation on a mainstream popular music collection. The experiment results show that our approach has achieved 71% of accuracy and 79% of reliability in identifying structural boundaries in music audio signals. These measures indicate that the performance of our method improves the results reported in the still scarce literature that includes quantitative analyses. 1. INTRODUCTION Music structure varies widely from composer to composer and from piece to piece. Transformation, repetition, elaboration and simplification of music materials help to create the unique identity of music. Hence, it is believed that structural description provides a powerful way of interacting with audio content (i.e. browsing, summarizing, retrieving and identifying). Seeing this uniqueness of music structure, it is interesting to ask the question: is it possible to detect non-trivial/significant structural changes (i.e. intro->verse, verse->chorus, chorus->bridge, etc.) in music audio signals? This paper presents a novel, two-phased approach to this problem based on audio content analysis and similarity computation. In order to obtain appropriate musical content descriptions to detect structural changes, we propose a combination set of low-level descriptors to be extracted from music audio signals. In this paper, we address the problem of finding acceptable structural boundaries, without prior knowledge about musical structure. There is a second related problem consisting on assigning labels to the found segments. This will be reported in the first coming publication.
Oxalate Decarboxylase from Collybia velutipes

Oxalic acid is present as nutritional stress in many crop plants like Amaranth and Lathyrus. Oxalic acid has also been found to be involved in the attacking mechanism of several phytopathogenic fungi. A full-length cDNA for oxalate decarboxylase, an oxalate-catabolizing enzyme, was isolated by using 5′-rapid amplification of cDNA ends-polymerase chain reaction of a partial cDNA as cloned earlier from our laboratory (Mehta, A., and Datta, A. (1991) J. Biol. Chem. 266, 23548–23553). By screening a genomic library from Collybia velutipes with this cDNA as a probe, a genomic clone has been isolated. Sequence analyses and comparison of the genomic sequence with the cDNA sequence revealed that the cDNA is interrupted with 17 small introns. The cDNA has been successfully expressed in cytosol and vacuole of transgenic tobacco and tomato plants. The transgenic plants show normal phenotype, and the transferred trait is stably inherited to the next generation. The recombinant enzyme is partially glycosylated and shows oxalate decarboxylase activity in vitro as well as in vivo. Transgenic tobacco and tomato plants expressing oxalate decarboxylase show remarkable resistance to phytopathogenic fungus Sclerotinia sclerotiorum that utilizes oxalic acid during infestation. The result presented in the paper represents a novel approach to develop transgenic plants resistant to fungal infection.
People Detection and Tracking with World-Z Map from a Single Stereo Camera

In this paper we propose a new people tracking system that uses a single stereo camera fixed at a high position and observing the scene at an oblique angle. We introduce the notion of world-Z map and show that 3D people detection and segmentation can be performed efficiently in this map and outperforms significantly the methods based on depth or plan-view. Detection and tracking play complementary roles, we derive a probabilistic framework for tracking based on motion. The system successfully deals with very complex situations without loosing track of people in highly cluttered scenes for long observation periods and achieves around 10fps on a single PC.
Experiments at the University of Edinburgh for the TREC 2006 QA Track

We describe experiments carried out at the University of Edinburgh for our TREC 2006 QA participation. Our main effort was to develop an approach to QA that is based on frame semantics. Two algorithms were implemented to this end, building on the lexical resources FrameNet, PropBank and VerbNet. The first algorithm uses the resources to generate potential answer templates to a given question, which are then used to pose exact, quoted queries to a web search engine and confirm which of the results contain an actual answer to the question. The second algorithm bases search queries on key words only, but it can recognize answers in a wider range of syntactic variants in its candidate sentence analysis stage. We discuss both approaches when applied to each of the resources and a combination of these. We also describe how–in a later step–the found answer candidates are mapped to the AQUAINT corpus and how we answered other questions.
Freedom of will

freedom of the will by is among the most effective vendor publications in the world? Have you had it? Not? Ridiculous of you. Now, you could get this incredible book just here. Locate them is layout of ppt, kindle, pdf, word, txt, rar, as well as zip. How? Simply download and even check out online in this website. Currently, never ever late to read this freedom of the will. Seeking certified reading resources? We have freedom of the will to read, not only read, but likewise download them or perhaps review online. Locate this terrific publication writtern by by now, merely below, yeah only here. Get the data in the kinds of txt, zip, kindle, word, ppt, pdf, and rar. Once again, never miss out on to check out online and download this book in our site below. Click the link. Our goal is always to offer you an assortment of cost-free ebooks too as aid resolve your troubles. We have got a considerable collection of totally free of expense Book for people from every single stroll of life. We have got tried our finest to gather a sizable library of preferred cost-free as well as paid files. GO TO THE TECHNICAL WRITING FOR AN EXPANDED TYPE OF THIS FREEDOM OF THE WILL, ALONG WITH A CORRECTLY FORMATTED VERSION OF THE INSTANCE MANUAL PAGE ABOVE.
The influence of valence and decision difficulty on self-referential processing

Self-referential processing is defined as the process by which a person becomes aware that specific contents are related to his or her own self. Cortical midline structures (CMS), such as dorsal and medial prefrontal cortex, and regions such as inferior frontal cortex, insula, and temporal pole have been implicated in self-referential processing. However, the specific contribution of each of these areas is still largely unknown. More particularly, not many studies have examined the influence of valence and decision making difficulty on regions involved in self-referential processing. In this study, participants evaluated how well personality traits, differing in valence and decision difficulty, described themselves or the current US President. In line with predictions, ventral, rostral, and dorsal parts of medial prefrontal cortex showed greater activity when participants judged traits about themselves relative to judging traits about the current US President. However, none of these regions showed significant modulation by trait valence. Increasing trait decision difficulty was associated with increased activity within dorsal medial prefrontal cortex and bilateral anterior insula. However, there was very minimal overlap (6/119 voxels, i.e., 5%) of the regions of dorsal medial prefrontal cortex implicated in self-referential processing and those implicated in trait decision difficulty. The results are interpreted within current accounts of self-referential processing.
Repeat Coronary Computed Tomographic Angiography in Patients With a Prior Scan Excluding Significant Stenosis

Background—ACCF/SCCT/ACR/AHA/ASE/ASNC/NASCI/SCAI/SCMR 2010 Appropriate Use Criteria for Cardiac Computed Tomography (AUC2010) does not incorporate prior coronary computed tomographic angiography (CCTA) results in the appropriateness of a CCTA examination. The purpose of this study was to explore the criteria for forgoing repeat CCTA among patients with clinical scenarios suggesting CCTA as appropriate after prior CCTA excluding coronary artery disease. Methods and Results—Among patients from a single center (February 2006 to April 2013) who underwent appropriate CCTA based on AUC2010, consecutive 555 CCTAs, which had a prior CCTA excluding significant stenosis (>50% stenosis in diameter), were selected. The median time difference between the studies was 34.2 (Q1–Q3, 22.9–50.1) months. Significant stenosis was detected at the time of repeat scan (by CCTA or subsequent catheter angiography) in 13.3% (74 of 555). A multivariable logistic model (C-statistic, 0.74; bootstrapped overfitting bias, 0.8%) identified 3 predictors of significant stenosis: time difference between the studies >3 years (adjusted odds ratio, 2.1; 95% confidence interval, 1.2–3.5), diabetes mellitus (odds ratio, 2.4; 95% confidence interval,1.4–4.3), and 26% to 50% stenosis on the initial CCTA (odds ratio, 5.6; 95% confidence interval, 3.2–9.6). When these 3 factors were all absent (corresponding to 31.9% of the population), the probability of significant stenosis was 4.5% (95% confidence interval, 2.7–7.4%), whereas 17.1% of patients had significant stenosis among those with at least 1 positive variable. When coronary arteries were completely normal at the initial scan, the prevalence of significant stenosis was only 1.8% irrespective of other factors, and no patient underwent revascularization. Conclusions—Nondiabetic patients with a prior CCTA <3 years showing no or ⩽25% stenosis had a <5% prevalence of significant stenosis. The value of repeat CCTA in this group is likely small, especially when the prior CCTA demonstrated normal coronaries, even if the clinical scenario considered a CCTA appropriate.
Hemodynamic response to fluid management in children undergoing dexmedetomidine sedation for MRI.

OBJECTIVE Dexmedetomidine is administered for pediatric sedation for MRI studies. It has the advantage of preserving respiratory function and producing a sedation state identical to that of natural sleep. It can, however, cause a dose-dependent decrease in systemic blood pressure in children. The purpose of this study was to investigate whether i.v. fluid loading with normal saline solution before the initiation of dexmedetomidine administration would affect the frequency of hypotension. MATERIALS AND METHODS Quality assurance data on consecutively registered children who were sedated with dexmedetomidine for MRI were reviewed. All children received a bolus of 3 μg/kg dexmedetomidine followed by a continuous infusion of 2 mg/ kg/h. A normal saline fluid bolus consisting of 0, 10, or 20 mL/kg was administered to each child within 1 hour before initiation of dexmedetomidine administration. Hypotension was defined as a greater than 20% decrease in mean arterial blood pressure from baseline. RESULTS Sedation was administered to 1692 children. Data on fluid administration were missing in three cases. In the other cases, 252 (14.9%) children received 0 mL/kg of normal saline solution, 598 (35.3%) received 10 mL/kg, and 839 (49.6%) received 20 mL/kg. In a multiple logistic regression model controlled for confounding variables, the odds of development of hypotension with 10 mL/kg of fluid decreased 53% (odds ratio, 0.47; 95% CI, 0.28-0.79; p = 0.004) compared with 0 mL/kg. CONCLUSION Administration of 10 mL/kg of normal saline solution before the initiation of dexmedetomidine administration for pediatric MRI sedation is effective in decreasing the incidence of observed hypotension.
Magnetization transfer imaging in progressive multifocal leukoencephalopathy

Article abstract-We report a patient with biopsy-proven progressive multifocal leukoencephalopathy (PML) who was serially imaged with MRI and magnetization transfer imaging. The magnetization transfer ratio (MTR) was profoundly and significantly diminished when compared with normal control subjects. The pattern of MTR was distinct from that of MS and periventricular ischemic white matter disease. Magnetization transfer imaging techniques may aid in the differential diagnosis of PML. NEUROLOGY 1997;48: 534-536