Miracle-dz/UniFAR-FTUs huggingface dataset:
WiseTex-based models of permeability of textiles

The software package WiseTex implements a generalised description of the internal structure of textile reinforcements on the unit cell level, integrated with mechanical models of the relaxed and deformed state of 2D and 3D woven, twoand three-axial braided, weft-knitted and non-crimp warp-knit stitched fabrics and laminates. The paper describes its integration with modelling of resin flow on meso-level. Calculation of permeability is based on a voxel representation of the unit cell volume. A voxel is either empty (pore) or filled with fibres. The flow of the fluid in the pores is governed by Navier-Stokes equations (NS-voxels), inside the permeable tows – by Brinkman equation (Bvoxels). In the latter case local permeability (micro-level) is calculated with the formulae of Gebart and Berdichevsky for a unidirectional array of fibres. These equations are solved by numerical schemes based on: (1) lattice Boltzmann, (2) finite difference or (3) finite element algorithms. The homogenised permeability of a unit cell is then determined using an average flux of the fluid through the unit cell under periodic boundary conditions for the given pressure difference on the unit cell facets.
CD70 limits atherosclerosis and promotes macrophage function

Summary The costimulatory molecule CD70 is expressed on activated immune cells and is known to modulate responses of T, B, and NK cells via its receptor CD27. Until now, there is only limited data describing the role of CD70 in atherosclerosis. We observed that ruptured human carotid atherosclerotic plaques displayed higher CD70 expression than stable carotid atherosclerotic plaques, and that CD70 expression in murine atheroma localized to macrophages. Lack of CD70 impaired the inflammatory capacity (e. g. reactive oxygen species and nitric oxide production) of bone marrow-derived macrophages, increased both M1-like and M2-like macrophage markers, and rendered macrophages meta-bolically inactive and prone to apoptosis. Moreover, CD70-deficient macrophages expressed diminished levels of scavenger receptors and ABC-transporters, impairing uptake of oxidised low-density lipoprotein (oxLDL) and cholesterol efflux, respectively. Hyperlipidaemic Apoe −/− mice reconstituted with CD70-deficient bone marrow displayed a profound increase in necrotic core size, plaque area, and number of lesional macrophages as compared to mice receiving control bone marrow. Accordingly, 18 week-old, chow diet-fed CD70-deficient Apoe−/−mice displayed larger atheroma characterised by lower cellularity and more advanced plaque phenotype than Apoe−/− mice. In conclusion, CD70 promotes macrophage function and viability and is crucial for effective phagocytosis and efflux of oxLDL. Deficiency in CD70 results in more advanced atheroma. Our data suggest that CD70 mitigates atherosclerosis at least in part by modulating macrophage function. Note: The review process for this manuscript was fully handled by G. Y. H. Lip, Editor in Chief. Supplementary Material to this article is available online at www.thrombosis-online.com.
Vibration control of plates with active constrained-layer damping

Bending vibration of flat plates is controlled using patches of active constrained layer damping (ACLD) treatments. Each ACLD patch consists of a visco-elastic damping layer which is sandwiched between two piezo-electric layers. The first layer is directly bonded to the plate to sense its vibration and the second layer acts as an actuator to actively control the shear deformation of the visco-elastic damping layer according to the plate response. With such active/passive control capabilities the energy dissipation mechanism of the visco-elastic layer is enhanced and its damping characteristics of the plate vibration is improved. A finite element model is developed to analyze the dynamics and control of flat plates which are partially treated with multi-patches of ACLD treatments. The model is validated experimentally using an aluminum plate which is 0.05 cm thick, 25.0 cm long, and 12.5 cm wide. The plate is treated with two ACLD patches. Each of which is made of SOUNDCOAT (Dyad 606) visco- elastic layer sandwiched between two layers of AMP/polyvinylidene fluoride (PVDF) piezo- electric films. The piezo-electric axes of the patches are set at zero degrees relative to the plate longitudinal axis to control the bending mode. The effect of the gain of a proportional control action on the system performance is presented. Comparisons between the theoretical predictions and the experimental results suggest the validity of the developed finite element model. Also, comparisons with the performance of conventional passive constrained layer damping clearly demonstrate the merits of the ACLD as an effective means for suppressing the vibration of flat plates.
Structure and surface properties of plasma polymerized acrylic acid layers

Thin plasma polymerized layers of acrylic acid (PPAA) were deposited onto polyethylene and muscovite mica surfaces. Structure and surface properties of the deposited layer depend on the polymerization conditions. The content of carboxylic groups in the layer decreases, whereas the degree of crosslinking or branching increases, with increasing discharge power. A soft, sticky layer with a low contact angle against water is obtained when a low discharge power (5 W) is used. In contrast, a hard film with a rather high water contact angle is obtained when the discharge power is high (50 W). A surface force apparatus was employed to study some film properties including adhesion force, crack formation, and capillary condensation. The adhesion force between plasma polymerized acrylic acid layers prepared at a low discharge power is high in dry air. It decreases remarkably in humid air and no adhesion is observed in water. In dry air, the adhesion force between PPAA layers decreases as the discharge power increases.
Temperature effect on light polarization in uniaxial crystals

It has been shown that changes in temperature of uniaxial single crystal are accompanied by changes in the polarization plane angular position and the light intensity that subsequently passes through the polarizer, uniaxial crystal, and analyzer. These effects introduce systematic errors in the results of researching the nonlinear processes. To minimize this harmful effect, polarization researches must be carried out at a constant sample temperature. For example, research of the nonlinear polarization processes in CdS should be done with a sample temperature uncertainty no higher than ±1 K.
In-datacenter performance analysis of a tensor processing unit

Many architects believe that major improvements in cost-energy-performance must now come from domain-specific hardware. This paper evaluates a custom ASIC-called a Tensor Processing Unit (TPU)-deployed in datacenters since 2015 that accelerates the inference phase of neural networks (NN). The heart of the TPU is a 65,536 8-bit MAC matrix multiply unit that offers a peak throughput of 92 TeraOps/second (TOPS) and a large (28 MiB) software-managed on-chip memory. The TPU's deterministic execution model is a better match to the 99th-percentile response-time requirement of our NN applications than are the time-varying optimizations of CPUs and GPUs that help average throughput more than guaranteed latency. The lack of such features helps explain why, despite having myriad MACs and a big memory, the TPU is relatively small and low power. We compare the TPU to a server-class Intel Haswell CPU and an Nvidia K80 GPU, which are contemporaries deployed in the same datacenters. Our workload, written in the high-level TensorFlow framework, uses production NN applications (MLPs, CNNs, and LSTMs) that represent 95% of our datacenters' NN inference demand. Despite low utilization for some applications, the TPU is on average about 15X–30X faster than its contemporary GPU or CPU, with TOPS/Watt about 30X–80X higher. Moreover, using the GPU's GDDR5 memory in the TPU would triple achieved TOPS and raise TOPS/Watt to nearly 70X the GPU and 200X the CPU.
Atopic dermatitis phenotypes and the need for personalized medicine

Purpose of review To describe recent developments in therapies which target the molecular mechanisms in atopic dermatitis. Recent findings Current advances in the understanding of the molecular basis of atopic dermatitis are leading to the stratification of different atopic dermatitis phenotypes. New therapies offer the option to target-specific molecules involved in the pathophysiology of atopic dermatitis. Current new therapies under investigation aim to modulate specific inflammatory pathways associated with distinctive atopic dermatitis phenotypes, which would potentially translate into the development of personalized, targeted-specific treatments of atopic dermatitis. Summary Despite the unmet need for well tolerated, effective, and personalized treatment of atopic dermatitis, the current standard treatments of atopic dermatitis do not focus on the individual pathogenesis of the disease. The development of targeted, phenotype-specific therapies has the potential to open a new promising era of individualized treatment of atopic dermatitis.
Development of Contaminant Detection System using HTS SQUIDs

豊橋技術科学大学, ○ 大谷 剛義,内田 陽介, 田中 三郎 Toyohashi Univ. of Technol. , ○T. Otani, Y. Uchida, S. Tanaka E-mail: to013@edu.imc. tut.ac. jp 1. はじめに 食品の製造工程において加工機械の破損等 により金属異物が混入する事故が発生し、社会 問題となっている。 既に渦電流式金属検査装置 や X 線異物検査装置が広く普及しているが、 十分な検出感度が得られていないため、高感度 な金属異物検出技術が求められている。 我々は これまでに HTS dc-SQUID を用いた磁性金属 異物検査装置の開発を行い、更に Julicher SQUID GmbH 社のHTS rf-SQUID magnetometer を用い異物-センサ間距離(Stand-off) 68mm で鉄球φ0. 5mm まで検出可能な、食品向け異物 検査装置の試作開発に成功してきた。 本研究では、20m/分のライン速度を想定し、 食品厚さ 100mm まで検査可能なシステムを試 作。 食品高さ≧80mm において、鉄球φ0. 5mm を検出可能なシステムを開発することを目的 とした新たに装置を試作し、検出性能評価を行 った。 2. 検出原理とシステム 対象となる食品を予め磁気回路を通過させ ることにより、食品内の磁性金属を磁化し、 SQUID センサにより残留磁化の計測を行う。 Fig. 1 にシステムの概略図を示す。 3 個の SQUID(ホワイトノイズレベル 200 fT/ Hz @1kHz)を個別ガラスデュワに入れ、
Trait Emotional Intelligence and the Big Five

Trait emotional intelligence (EI) is a constellation of emotion-related self-perceptions located at the lower levels of personality hierarchies. This article examines the validity of the Trait Emotional Intelligence Questionnaire–Child Form and investigates its relationships with Big Five factors and cognitive ability. A total of 690 children (317 Males; M Age = 10.25 years; SD = 1.58 years) completed the TEIQue-CF, the Raven Progressive, Matrices and the Big Five Questionnaire; in addition, a subsample of 136 participants answered to Depression and Anxiety scales. Results evidenced that TEIQue-CF is a reliable measure of Trait EI that is partially determined by all of the Big Five factors but independent of cognitive ability. Trait EI predicts depression and anxiety scores over and above the five higher order personality dimensions.
Beam Steering Mechanism for EarthCARE Atmospheric Lidar Instrument- An Improved Piezoelectic Tip-Tilt Mechanism

In the context of the ATLID instrument [1] embedded in the EarthCARE mission (Earth Cloud, Aerosol and Radiation Explorer), a Beam Steering Assembly is deviating a pulsed high energy UV laser beam to compensate the pointing misalignment between the emission and reception paths of ATLID with a very high stability and high resolution. Within the EarthCARE mission, led by ESA, Astrium i s responsible for the ATLID instrument. The BSA development, manufacture and tests were assigned by Astrium to Sodern, an EADS filial. In this context, Cedrat Technologies was sub-contra cted by Sodern to design, manufacture and test the performances of Beam Steering Mechanism flights models. This paper points out the main mechanism design issues: • High performances; • Mechanical and thermal stability; • Low power consumption; • High integration level; • High reliability and safety; • Cleanliness requirements. and examines how these issues have been approached by Cedrat Technologies and Sodern. Test results are reported when available.
Manipulating the antioxidant capacity of halophytes to increase their cultural and economic value through saline cultivation

Halophytes, salt-tolerant plants, are a source of valuable secondary metabolites with potential as functional foods or nutraceuticals. We are interested in finding the optimal cultivation conditions for increasing the contents of these valuable compounds. Growth conditions away from the optimum can induce stress resulting in changes in secondary metabolites. We analyzed metabolites with antioxidant capacity in seedlings and plants from different families and habitats grown under different salt concentrations. We show that it is possible to manipulate the antioxidant capacity of plants and seedlings by altering the saline growing environment, the length of time under saline cultivation and the developmental stage.
Dietary resveratrol supplementation prevents transport-stress-impaired meat quality of broilers through maintaining muscle energy metabolism and antioxidant status

&NA; This experiment was to evaluate the effect of dietary resveratrol (Res) supplementation (0, 400 mg/kg) on growth performance, meat quality, and muscle anaerobic glycolysis and antioxidant capacity of transported broilers. A total of 360 21‐day‐old male Cobb broilers was randomly allotted to 2 dietary treatments (Res‐free group and Res group) with 12 replicates of 15 birds each. On the morning of d 42, after a 9‐hour fast, 24 birds (2 birds of each replicate) were selected from the Res‐free group and then equally placed into 2 crates, and the other 12 birds (one bird of each replicate) were selected from the Res group and then placed into the other crate. All birds in the 3 crates were transported according to the following protocols: 0‐hour transport of birds in the Res‐free group (control group), 3‐hour transport of birds in the Res‐free group (T group), and 3‐hour transport of birds in the Res group (T + Res group). The results showed that Res not only improved feed conversion ratio (P < 0.05) but also tended to improve birds' final body weight (P < 0.10). In the Res‐free group, a 3‐hour transport increased serum corticosterone concentration, muscle malondialdehyde (MDA) and lactate contents, and muscle lactate dehydrogenase (LDH) activity, while it decreased muscle glycogen content, total superoxide dismutase (T‐SOD), and glutathione peroxidase (GSH‐PX) activities (P < 0.05), which induced decreased breast meat quality (lower pH24h and higher drip loss and L*24 h, P < 0.05). Nevertheless, compared with the T group, Res increased muscle glycogen content and T‐SOD and GSH‐PX activities (P < 0.05 or P < 0.10), while it decreased muscle MDA content and LDH activity (P < 0.05), which is beneficial to the meat quality maintenance of transported broilers (lower drip loss, L*24 h, and higher pH24h, P < 0.05 or P < 0.10). This study provides the first evidence that dietary resveratrol supplementation prevents transport‐stress‐impaired meat quality of broilers, possibly through decreasing the muscle anaerobic glycolysis metabolism and improving the muscle antioxidant capacity.
Characterization of myosin heavy chains from the mantle muscles of cephalopods

Myosin heavy chain (MyHC) genes from the mantle muscles of three cephalopod species, namely, golden cuttlefish Sepia esculenta, Japanese common squid Todarodes pacificus, and spear squid Loligo bleekeri were subjected to synthesis of first strand cDNA by reverse transcription-PCR. As a result of sequencing of the obtained cDNA fragments, the MyHCs from S. esculenta and L. bleekeri were found to consist of 1936 amino acids, while T. pacificus MyHC consisted of 1939 residues. The sequences were found to be 73%, 55%, and 41% identical to those of the Ca2+-regulated scallop MyHCs, human skeletal MyHC, and chicken gizzard (smooth muscle) MyHC, respectively. The cephalopod MyHCs conserved ATP- and actin-binding sites as well as light chain binding sites in the head (S1) region with the clear differences in sequence homology from those of higher organisms, and typical ? -helical heptad repeats involved in the formation of coiled-coil structure in the rod region. The sequences of the two surface loops at the 25/50 kDa and 50/20 kDa junctions of the motor domain were found to be conserved among cephalopods compared to those from the other sources. In the phylogenetic tree based on the amino acid sequences, the cephalopod MyHCs formed a cluster, clearly different from the other invertebrate counterparts, in accordance with the results of tertiary structure modeling of the head regions.
Global Assessment of Seasonal Potential Distribution of Mediterranean Fruit Fly, Ceratitis capitata (Diptera: Tephritidae)

The Mediterranean fruit fly (Medfly) is one of the world's most economically damaging pests. It displays highly seasonal population dynamics, and the environmental conditions suitable for its abundance are not constant throughout the year in most places. An extensive literature search was performed to obtain the most comprehensive data on the historical and contemporary spatio-temporal occurrence of the pest globally. The database constructed contained 2328 unique geo-located entries on Medfly detection sites from 43 countries and nearly 500 unique localities, as well as information on hosts, life stages and capture method. Of these, 125 localities had information on the month when Medfly was recorded and these data were complemented by additional material found in comprehensive databases available online. Records from 1980 until present were used for medfly environmental niche modeling. Maximum Entropy Algorithm (MaxEnt) and a set of seasonally varying environmental covariates were used to predict the fundamental niche of the Medfly on a global scale. Three seasonal maps were also produced: January-April, May-August and September-December. Models performed significantly better than random achieving high accuracy scores, indicating a good discrimination of suitable versus unsuitable areas for the presence of the species.
Algorithms for efficient symbolic detection of faults in context-aware applications

Context-aware and adaptive applications running on mobile devices pose new challenges for the verification community. Current verification techniques are tailored for different domains (mostly hardware) and the kind of faults that are typical of applications running on mobile devices are difficult (or impossible) to encode using the patterns of ldquotraditionalrdquo verification domains. In this paper we present how techniques similar to the ones used in symbolic model checking can be applied to the verification of context-aware and adaptive applications. More in detail, we show how a model of a context-aware application can be encoded by means of ordered binary decision diagrams and we introduce symbolic algorithms for the verification of a number of properties.
Voltage-dependent Gating of the Cystic Fibrosis Transmembrane Conductance Regulator Cl− Channel

When excised inside-out membrane patches are bathed in symmetrical Cl−-rich solutions, the current-voltage (I-V) relationship of macroscopic cystic fibrosis transmembrane conductance regulator (CFTR) Cl− currents inwardly rectifies at large positive voltages. To investigate the mechanism of inward rectification, we studied CFTR Cl− channels in excised inside-out membrane patches from cells expressing wild-type human and murine CFTR using voltage-ramp and -step protocols. Using a voltage-ramp protocol, the magnitude of human CFTR Cl− current at +100 mV was 74 ± 2% (n = 10) of that at −100 mV. This rectification of macroscopic CFTR Cl− current was reproduced in full by ensemble currents generated by averaging single-channel currents elicited by an identical voltage-ramp protocol. However, using a voltage-step protocol the single-channel current amplitude (i) of human CFTR at +100 mV was 88 ± 2% (n = 10) of that at −100 mV. Based on these data, we hypothesized that voltage might alter the gating behavior of human CFTR. Using linear three-state kinetic schemes, we demonstrated that voltage has marked effects on channel gating. Membrane depolarization decreased both the duration of bursts and the interburst interval, but increased the duration of gaps within bursts. However, because the voltage dependencies of the different rate constants were in opposite directions, voltage was without large effect on the open probability (Po) of human CFTR. In contrast, the Po of murine CFTR was decreased markedly at positive voltages, suggesting that the rectification of murine CFTR is stronger than that of human CFTR. We conclude that inward rectification of CFTR is caused by a reduction in i and changes in gating kinetics. We suggest that inward rectification is an intrinsic property of the CFTR Cl− channel and not the result of pore block.
Coping as a Mediator Between Parental Attachment and Resilience: An Examination of Differential Effects Between Chinese Adolescents From Single Parent Families Versus Those From Intact Families

The crude divorce rate has been increasing steadily for over a decade in China. Consequently, more and more children have to face the challenge of growing up in single parent families. The current study investigated the mediating effects of problem-oriented and emotion-oriented coping on the relationship between parental attachment and psychological resilience among a sample of Chinese adolescents from single parent families and intact families. Participants were 975 high school students (44.30% males; aged 15–19 years, M = 16.32 years, SD = 0.74), 871 from intact families and 104 from single parent families. Structural equation modeling showed that security in maternal attachment was positively associated with resilience through the indirect effect of reduced emotion-oriented coping among adolescents from single parent families. Among adolescents from intact families, security in maternal attachment was both directly associated with resilience and indirectly through enhanced problem-oriented and reduced emotion-oriented coping. Security in paternal attachment was associated with resilience both directly and indirectly through enhanced problem-oriented coping as well among those from intact families. Female adolescents exhibited significantly lower levels of resilience than male adolescents did regardless of the marital status of their parents. Limitations and suggestions for future research are discussed.