Miracle-dz/UniFAR-FTUs huggingface dataset:
Intravascular device administration sets: replacement after standard versus prolonged use in hospitalised patients—a study protocol for a randomised controlled trial (The RSVP Trial)

Introduction Vascular access devices (VADs), such as peripheral or central venous catheters, are vital across all medical and surgical specialties. To allow therapy or haemodynamic monitoring, VADs frequently require administration sets (AS) composed of infusion tubing, fluid containers, pressure-monitoring transducers and/or burettes. While VADs are replaced only when necessary, AS are routinely replaced every 3–4 days in the belief that this reduces infectious complications. Strong evidence supports AS use up to 4 days, but there is less evidence for AS use beyond 4 days. AS replacement twice weekly increases hospital costs and workload. Methods and analysis This is a pragmatic, multicentre, randomised controlled trial (RCT) of equivalence design comparing AS replacement at 4 (control) versus 7 (experimental) days. Randomisation is stratified by site and device, centrally allocated and concealed until enrolment. 6554 adult/paediatric patients with a central venous catheter, peripherally inserted central catheter or peripheral arterial catheter will be enrolled over 4 years. The primary outcome is VAD-related bloodstream infection (BSI) and secondary outcomes are VAD colonisation, AS colonisation, all-cause BSI, all-cause mortality, number of AS per patient, VAD time in situ and costs. Relative incidence rates of VAD-BSI per 100 devices and hazard rates per 1000 device days (95% CIs) will summarise the impact of 7-day relative to 4-day AS use and test equivalence. Kaplan-Meier survival curves (with log rank Mantel-Cox test) will compare VAD-BSI over time. Appropriate parametric or non-parametric techniques will be used to compare secondary end points. p Values of <0.05 will be considered significant. Ethics and dissemination Relevant ethical approvals have been received. CONSORT Statement recommendations will be used to guide preparation of any publication. Results will be presented at relevant conferences and sent to the major organisations with clinical practice guidelines for VAD care. Trial registration number Australian New Zealand Clinical Trial Registry (ACTRN 12610000505000).
Effect of 2% chlorhexidine digluconate application and water storage on the bond strength to superficial and deep dentin

The aim of the present in vitro study was to evaluate the effect of chlorhexidine, applied before a self-etching adhesive system (Clearfil SE Bond) on microtensile bond strength to superficial and deep dentin (DD), immediately and after six months of water storage (WS). Forty dentin specimens were divided into two groups according to dentin depth: superficial and deep. The specimens were then divided according to the solution to be applied (n = 10): CLX: 2% chlorhexidine (passively applied for 60 s) and NT (no treatment). A self-etching adhesive system was applied according to the manufactures instructions, with composite restorative placed on the dentin surface. After 24 h, dentin–resin blocks were sectioned into beam-shaped specimens that were submitted to microtensile bond strength testing either immediately or after six months of WS. Data were submitted to three-way ANOVA (α = 0.05). Bond strength values for the deep dentin group were significantly lower than those observed for superficial dentin (SD) (p = 0.002), whether chlorhexidine solution had been applied or not. There was no statistical difference in bond strength for specimens tested after 24 h and 6 months of WS. The application of chlorhexidine did not affect immediate and long-term bond strength to dentin. Bond strength in deep dentin was lower than in SD.
Achieving High Organization Performance through Servant Leadership

This empirical paper investigates whether a servant leader can develop a corporate culture that attracts or develops other servant leaders. Using the survey developed by Barbuto and Wheeler (2006), servant leader characteristics in managers were measured at three high-performing organizations. Results indicate that servant leaders can develop a culture of followers who are servant leaders themselves. This is one of the few studies to empirically test the model of servant leadership in an organizational environment. The success these servant leaders have achieved in a for-profit, demanding environment suggests this leadership style is viable for adoption by other firms.
Dependency-based rules for grammar checking with LanguageTool

This paper describes a possible extension of well-known open source grammar checking software LanguageTool. The proposed extension allows the developers to write grammar rules that rely on natural language parser-supplied dependency trees. Such rules are indispensable for the analysis of word-word links in order to handle a variety of grammar errors, including improper use of articles, incorrect verb government, and wrong word form agreement.
What is a Relationship Worth? Repeated Exchange and the Development and Deployment of Relational Capital

Organization scholars have highlighted the value of relationships in fostering effective exchange, suggesting that repeated exchange creates a relational asset with latent value derived from elevated social connections, norms, and simple expectations of exchange continuity. Yet the empirical evidence supporting such claims remains largely indirect. As a consequence, few studies have been able to directly examine how contextual factors shape the accumulation of this relational asset or define its value in application. We directly measure the value of relationships between suppliers and a large buyer, using the buyer’s choices in Internet-enabled procurement auctions to estimate the degree to which stronger relationship histories with suppliers increase willingness to pay for high-volume commodity-like parts. Our setting also allows us to examine how this willingness to pay for relationships is shaped by the social context in which they develop and by the exchange context in which they are subsequently depl.
Studies on the Bioequivalence of Different Strengths of Tablets Containing Clarithromycin

Summary The aim of the present studies, performed in two different groups of volunteers, was to compare the bioavailability of clarithromycin (CAS 81103-11-9) tablets (Klaromin®, test tablets) containing 250 mg (study 1) or 500 mg (study 2) of the drug with reference tablets of the same strength. Each study was conducted according to an open, randomized, single-dose, two-period crossover design in healthy volunteers with a wash-out period from 7 to 14 days. Blood samples were taken up to 24 h in both studies, and concentrations of clarithromycin and its principal active 14-hydroxy metabolite were determined by HPLC method. In the first study, the 90 % confidence interval for intra-individual ratios of AUC0–t and Cmax of clarithromycin were between 0.93 and 1.05 (AUC0–t) as well as between 0.90 and 1.18 (Cmax). In the second study, i.e. after administration of clarithromycin 500 mg tablets, the 90 % confidence interval for intra-individual ratios of AUC0–t and Cmax of clarithromycin were between 0.90 and 1.08 (AUC0–t) as well as between 0.85 and 1.22 (Cmax). All these values were within the acceptance ranges for bioequivalence studies. In both studies, the 90 % confidence interval for intra-individual ratios of AUC0–t and Cmax of 14-hydroxy-clarithromycin were also within the acceptance ranges, although the confidence intervals for these parameters were not planned to be compared with the acceptance ranges. In the light of the results of the studies reported here it can be concluded that the clarithromycin 250 mg and 500 mg test tablets are bioequivalent to the respective reference formulations.
Nitrate and ammonium lead to distinct global dynamic phosphorylation patterns when resupplied to nitrogen-starved Arabidopsis seedlings

Nitrogen is an essential macronutrient for plant growth and development. Inorganic nitrogen and its assimilation products control various metabolic, physiological and developmental processes. Although the transcriptional responses induced by nitrogen have been extensively studied in the past, our work here focused on the discovery of candidate proteins for regulatory events that are complementary to transcriptional changes. Most signaling pathways involve modulation of protein abundance and/or activity by protein phosphorylation. Therefore, we analyzed the dynamic changes in protein phosphorylation in membrane and soluble proteins from plants exposed to rapid changes in nutrient availability over a time course of 30 min. Plants were starved of nitrogen and subsequently resupplied with nitrogen in the form of nitrate or ammonium. Proteins with maximum change in their phosphorylation level at up to 5 min after nitrogen resupply (fast responses) included GPI-anchored proteins, receptor kinases and transcription factors, while proteins with maximum change in their phosphorylation level after 10 min of nitrogen resupply (late responses) included proteins involved in protein synthesis and degradation, as well as proteins with functions in central metabolism and hormone metabolism. Resupply of nitrogen in the form of nitrate or ammonium resulted in distinct phosphorylation patterns, mainly of proteins with signaling functions, transcription factors and transporters.
Microbial desulfurization of SBR ground rubber by Sphingomonas sp. and its utilization as filler in NR compounds

Microbial desulfurization of waste tyre rubber has been investigated with great efforts since 1990s, because waste rubber has created serious ecological and environmental problems. A microbial desulfurization technique for SBR ground rubber has been developed by a novel sulfur-oxidizing bacterium Sphingomonas sp. The adaptability of Sphingomonas sp. with SBR ground rubber was tested with the amounts of SBR ground rubber varying from 0.5 to 4% g/l. The sol fraction of desulfurized SBR ground rubber increased 70%, compared with SBR ground rubber without desulfurization. Fourier transform infrared spectroscopy-attenuated total reflectance (FTIR-ATR) spectrum and X-ray photoelectron spectroscopy (XPS) analysis of the desulfurized surface of vulcanized SBR flakes revealed that not only the oxidation of crosslinked SS and SC bonds, but also the rupture of CC double bonds had happened to SBR vulcanizates during microbial desulfurization. The cure characteristics, such as scorch time and optimum cure time of natural rubber (NR) vulcanizates filled, were found to decrease with increasing contents of desulfurized SBR ground rubber, due to some reactive groups on its surface. NR vulcanizates filled with desulfurized SBR ground rubber had lower crosslink density and hardness, higher tensile strength and elongation at break, compared with those filled with SBR ground rubber of the same amount. Dynamic mechanical properties indicated that there were better crosslink distribution and stronger interfacial bonding between NR matrix and desulfurized SBR ground rubber. Scanning electron microscope (SEM) photographs showed that the fracture surfaces of NR vulcanizates filled with desulfurized SBR ground rubber had more smooth morphologies. Copyright © 2010 John Wiley & Sons, Ltd.
Creating motion video summaries with partial audio-visual alignment

In this paper, we propose an audio-visual summarization system which creates an audio and a visual summary of a given video program separately, and then integrates the two summaries with a partial alignment. A bipartite graph-based audio-visual alignment algorithm is developed to efficiently find the best alignment solution that satisfies the predefined alignment requirements. With the proposed system, we strive to produce a motion video summary for the original video that: (1) provides a natural visual and audio content overview; and (2) maximizes the coverage for both audio and visual contents of the original video without having to sacrifice either of them. Such audio-visual summaries dramatically increase the information intensity and depth, and lead to a more effective video content overview.
Energy-Aware Scheduling Algorithm with Duplication on Heterogeneous Computing Systems

Efficient application scheduling is critical for achieving high performance in heterogeneous computing (HC) environments. Because of its importance, there are many researches on this problem and various algorithms have been proposed. Duplication-based algorithm is a kind of famous algorithm to solve scheduling problem, which achieve high performance on minimizing the overall completion time(makespan) of applications. However, they do not consider energy consumption. With the growing advocacy for green computing system, energy conservation has been an important issue and gained a particular interest. An existing technique to reduce energy consumption of application is dynamic voltage/frequcny scaling(DVFS), but its efficiency is affected by the overhead of time and energy caused by voltage scaling. In this paper, we propose a new energy-aware scheduling algorithm called Energy Aware Scheduling by Minimizing Duplication(EAMD), which considers the energy consumption as well as the makespan of applications. It adopts a subtle energy-aware method to determine and delete the abundant task copies in the schedules generated by duplication-based algorithms, which is easier to operate than DVFS and produces no extra time and energy consumption. This algorithm can reduce large amount of energy consumption while having the same makespan compared with duplication-based algorithms without energy awareness. Randomly generated DAGs are tested in our experiments. Experimental results show that EAMD can save up to 15.59% energy consumption for the existed duplication-based algorithms. Several factors affecting the performance are analyzed in the paper, too.
Touching from a distance: website fingerprinting attacks and defenses

We present a novel web page fingerprinting attack that is able to defeat several recently proposed defenses against traffic analysis attacks, including the application-level defenses HTTPOS and randomized pipelining over Tor. Regardless of the defense scheme, our attack was able to guess which of 100 web pages a victim was visiting at least 50% of the time and, with some defenses, over 90% of the time. Our attack is based on a simple model of network behavior and out-performs previously proposed ad hoc attacks. We then build a web site fingerprinting attack that is able to identify whether a victim is visiting a particular web site with over 90% accuracy in our experiments. Our results strongly suggest that ad hoc defenses against traffic analysis are not likely to succeed. Consequently, we describe a defense scheme that provides provable security properties, albeit with potentially higher overheads.
Crystallization Behavior and Curie Temperature Properties of Al Doped Nd-Fe-B Based Nanocomposite Permanent Magnet

The work is primarily concerned with the development of nanocrystalline Nd-Fe-B, based permanent magnet with high Curie temperature. An alloy of composition Fe81Nd7Al2B10 has been prepared using vacuum arc furnace and subjected to using Melt-Spinning process for preparation of amorphous flakes. Differential scanning calorimetry (DSC) has been performed to determine the crystallization temperature and activation energy of the melt spun amorphous ribbons. Subsequently the melt spun ribbon was subjected to annealing at below and above the crystallization temperatures to identify effect of Al on the Curie temperature. It was noteworthy for the effect of alloying Al above crystallization temperature. The Curie temperature increases to by almost 1.3 times with increase in annealing temperature.
Experimental Evidence That Competition Promotes Divergence in Adaptive Radiation

Interspecific competition driving divergence in adaptive radiation has not previously been tested experimentally. Natural selection on a morphologically variable species of stickleback fish was contrasted in the presence and absence of a close relative. Selection was nondirectional when the target species was alone, whereas addition of the second species favored individuals most different from it morphologically and ecologically. Disproportionately severe competition between similar phenotypes indicates frequency-dependent selection, verifying a crucial element of theory of competition and character divergence. The findings help resolve outstanding debates on the ecological causes of diversification and the evolutionary consequences of competitive interactions.
Making Vehicles Transparent Through V2V Video Streaming

The advent of infrastructureless vehicle-to-vehicle (V2V) communication has opened the opportunity to design driver-assistance systems that collect information from sensors residing in neighboring vehicles. Windshield-installed cameras are one example of a sensor that is becoming common in modern vehicles. Remotely accessing real-time images of these cameras using V2V communication enables a significant increase in the visual awareness of each driver. In this paper, we propose and evaluate the performance of a driver-assistance system that leverages on V2V communication and windshield-installed cameras to transform vision-obstructing vehicles into transparent tubular objects. This cooperative system is able to increase the visibility of drivers intending to overtake, thus making such critical maneuvers safer. Our system uses an augmented reality human-machine interface that is able to convey the increased visibility perspective in a straightforward fashion. We also show that the required latency for this intervehicle communication can be obtained using the Dedicated Short-Range Communications (DSRC) proposed for vehicular environments.
Nurses’ Use of iPads in Home Care—What Does It Mean to Patients?

Although the use of technology is growing, little is known about how patients perceive technology in the form of tools used by health professionals. The prevailing view in the literature is that technology is cold, compared with the warm hands of nurses, but research regarding nurses’ use of technology such as tablets is scarce. Even scarcer is research on how patients perceive the use of technological tools. This study examines patients’ perspectives on the use of iPads by home care nurses. Semistructured interviews were conducted with seven participants who were receiving home care in Denmark, aged 62 to 90 years, with different backgrounds and experiences with technology. Participants viewed nurses’ use of iPads as an everyday occurrence, reflecting societal growth in the use of technology, and some perceived it as a sign of professionalism with the potential to enhance care. Their perceptions varied somewhat according to their baseline knowledge and experience with the technology. Although nurses may view technology as cold, the findings suggest that patients have a slightly warmer view of it. More patient-centered research into the use of technology in healthcare is needed.
Revisiting the Soft X-Ray Excess Emission in Clusters of Galaxies Observed with XMM-Newton

We analyze XMM-Newton galaxy clusters Abell 1795, Abell S1101, Abell 1835, and MKW 3s in order to test whether their soft X-ray excess emission in the 0.2-0.5 keV band as reported by Kaastra et al. maintains after application of current knowledge of the XMM-Newton background and calibration. In this context, we examine the claim (Bregman & Lloyd-Davies) that the XMM-Newton sub-Galactic H I column density, and the accompanying soft excess continuum emission in the 0.2-0.5 keV band, is an artifact of an incorrect background subtraction. We show that since the cluster regions under scrutiny are within 500 kpc of the bright cluster center, the X-ray background level is negligible compared to the cluster emission level. Thus, at least in the central 500 kpc regions of the studied clusters, the reported soft excess is not a background artifact. We also study the possibility that the incomplete calibration information in the early phase of the XMM-Newton mission resulted in sub-Galactic H I column density, which was interpreted with the presence of a soft excess emitter. Our reanalysis of the four XMM-Newton observations with the MOS instruments yields evidence for the soft excess in all clusters. However, using the PN instrument, the best-fit H I column densities in Abell 1795, Abell 1835, and MKW 3s are at odds with the 2003 analysis of Kaastra et al. and in general agreement with those measured from 21 cm data in the direction of the clusters (Dickey & Lockman). Abell S1101 continues to feature a sub-Galactic NH also with the PN instrument, indicative of soft excess emission in both EPIC detectors. These differences are compatible with the current level of uncertainty in the calibration of both instruments.
Arabidopsis Deficient in Cutin Ferulate Encodes a Transferase Required for Feruloylation of ω-Hydroxy Fatty Acids in Cutin Polyester1[W][OA]

The cuticle is a complex aliphatic polymeric layer connected to the cell wall and covers surfaces of all aerial plant organs. The cuticle prevents nonstomatal water loss, regulates gas exchange, and acts as a barrier against pathogen infection. The cuticle is synthesized by epidermal cells and predominantly consists of an aliphatic polymer matrix (cutin) and intracuticular and epicuticular waxes. Cutin monomers are primarily C16 and C18 unsubstituted, ω-hydroxy, and α,ω-dicarboxylic fatty acids. Phenolics such as ferulate and p-coumarate esters also contribute to a minor extent to the cutin polymer. Here, we present the characterization of a novel acyl-coenzyme A (CoA)-dependent acyl-transferase that is encoded by a gene designated Deficient in Cutin Ferulate (DCF). The DCF protein is responsible for the feruloylation of ω-hydroxy fatty acids incorporated into the cutin polymer of aerial Arabidopsis (Arabidopsis thaliana) organs. The enzyme specifically transfers hydroxycinnamic acids using ω-hydroxy fatty acids as acyl acceptors and hydroxycinnamoyl-CoAs, preferentially feruloyl-CoA and sinapoyl-CoA, as acyl donors in vitro. Arabidopsis mutant lines carrying DCF loss-of-function alleles are devoid of rosette leaf cutin ferulate and exhibit a 50% reduction in ferulic acid content in stem insoluble residues. DCF is specifically expressed in the epidermis throughout all green Arabidopsis organs. The DCF protein localizes to the cytosol, suggesting that the feruloylation of cutin monomers takes place in the cytoplasm.
High Efficiency Radial Passive Magnetic Bearing

Passive magnetic bearing with Halbach array is presented in this paper. The array uses permanent magnets with radial and axial magnetization to augment the magnetic field on one side of the array and cancel it on the other side. The design of the bearing consists of ring-shaped magnets of 60x70 mm and 75x85 mm with different orientation of magnetization. The designed passive magnetic bearing has air gap of 2.5 mm, stiffness 129297 N/m and maximal value of load 200 N. The bearing ensures magnetic levitation and stabilization of rotor in a work point. The paper presents the design of the passive magnetic bearing as well as the experimental setup together with investigation results.