Miracle-dz/UniFAR-FTUs huggingface dataset:
Exploring the Relationship Between Campus Climate and Minority Stress in African American College Students

During recent decades, there has been a growth in research exploring the social experiences of African American students attending institutions of higher education. Research that examines minority stress suggests that students of color experience cognitive stressors specific to their racial identity or status as minorities on campus. Many studies have expanded on this knowledge in terms of academic achievement, retention, and adjustment to campus during the first year. The present study explored the concept of minority stress in relation to campus climate and the mental health of African American college students. The participants in this study consisted of eight college students from a predominantly White Midwestern university who identified as African American. Utilizing one-on-one interviews, the students discussed their experiences on campus, their perceptions of campus climate, the stress they experienced as students of color, and how these aspects may have contributed to symptoms of depression and anxiety. Information shared by the students indicated that campus climate and minority stress are closely associated with one another, especially when considering the racial status of the students. While students described feeling stress, discomfort, and burden due to campus climate and minority stress, the investigators were unable to determine if the symptoms described were, in fact, due to anxiety or depression.
An Experimental Approach for Locating the Current Distribution in Multiphase Buck Converters

The objective of this paper is to present a methodology for identifying the current flow in the capacitors of a multiphase buck converter by synchronously measuring the capacitor currents. A multiphase buck converter uses multiple parallel buck converters with different switching times to source a large amount of current. Currents in the primary capacitors of a multiphase buck converter are drawn by all phases of the converter; however, the phases switch asynchronously. Synchronizing to the switching of a specific phase reveals how the current from that phase is distributed among the capacitors throughout a circuit board. The proposed measurement method is illustrated by comparing an initial printed circuit board design to a new design to show the effect of better capacitor placement and the addition of a ground plane. The new design confines the phase currents to the capacitors close to the field effect transistors of the specific phase.
A clinical audit of the prescribing of celecoxib and rofecoxib in Australian rural general practice.

AIMS The new cyclooxygenase-2 (COX-2) selective inhibitors, celecoxib (Celebrex) and rofecoxib (Vioxx), have been widely prescribed since their launch. No reviews currently appear in the literature of prescribing patterns in Australia. This paper describes a self-audit of the clinical use of selective COX-2 inhibitor therapy undertaken with rural general practitioners (GPs) in Australia. METHODS A structured audit form was developed and distributed to interested GPs. The form was self-administered and focused on issues about COX-2 inhibitors and the types of patients who were receiving them, e.g. indications, patient demographics, risk factors and drug interactions. RESULTS A total of 627 patients were recruited (569 celecoxib and 58 rofecoxib). A range of doses was prescribed. Osteoarthritis was the most common indication (68.1%). Risk factors known for the nonselective nonsteroidal anti-inflammatory drugs were identified in 65.1% of patients, with the most common being advanced age, hypertension and previous peptic ulcer disease. Potential drug interactions were common. A variety of reasons for initiation of therapy was identified; these included perceived increased efficacy, safety and failure of other treatment. CONCLUSIONS These results show that COX-2 inhibitors are being prescribed for patients with multiple risk factors that may place the patient at increased risk of adverse drug reactions to a COX-2 inhibitor. The perception of improved safety and efficacy was common and is of concern. Limitations of the study include the reliance on self-reporting.
Location Theory: An Empirical Model and Selected Findings

structured on the postulates of competitive pricing, different costs among locations, and a given buying center. Under the assumption of pure competition, each firm faced a perfectly elastic demand curve; consequently, there existed an unlimited demand for the output of any firm at the prevailing price and all sellers had access to the buying center. The problem of finding the proper site was one of determining where cost would be at a minimum.
3,3,3′,3′-Tetramethyl-6,6′-bis[(pyridin-4-yl)methoxy]-1,1′-spirobiindane monohydrate

The asymmetric unit in the title compound, C33H34N2O2·H2O, consists of a V-shaped molecule and a water molecule to which it is hydrogen bonded. The angle between the mean planes of the two spiro-connected indane groups is 77.06 (5)°. The two five-membered rings of the indane groups have envelope conformations with the methylene atoms adjacent to the spiro C atom forming the flaps. They have deviations from the mean plane of the other four atoms in the rings of 0.374 (4) and 0.362 (4) Å. In the crystal, molecules are linked to form inversion dimers via O—H⋯N hydrogen bonds involving the pyridine N atoms and the solvent water molecule. The dimers are linked into a chain along the b axis by π–π stacking interactions between a pyridine ring and its centrosymmetrically related ring in an adjacent dimer. The centroid–centroid distance between the planes is 3.7756 (17) Å, the perpendicular distance is 3.4478 (11) Å and the offset is 1.539 Å.
A Study on the Improved Localization of a Mobile Robot by using Scale Invariant Feature and Odometry

One of the important factors of the autonomous mobile robot is to build a map for surround environment and estimate its localization. This paper deals with the method to improve localization result by using scale invariant feature with single camera. In detail, the mobile robot attaches monocular camera looking wall extracts scale invariant features in each image by using SIFT (scale invariant feature transform). And then, map building is carried out by the extracted features and stores it map database. After finishing feature map building, the robot finds some points matched with previous feature map and its pose by affine parameter in real time. Localization by using SIFT is accurate relatively, but it sometimes loses its pose because of the change of the lights. To compensate the following problem, we apply the compensation method that uses the odometry information of the mobile robot. We verify the improved localization performance of the mobile robot from the experiments.
Channel Stress and Ballistic Performance Advantages of Gate-All-Around FETs and Inserted-Oxide FinFETs

Detailed stress modeling of various three-dimensional (3-D) MOSFET designs reveals that the “inserted-oxide” FinFET and gate-all-around (GAA) stacked-nanowire MOSFET (GAAFET) exhibit increased longitudinal stress and decreased transverse stress in both p-channel and n-channel devices, as compared against the bulk FinFET. By combining 3-D electrostatics modeling with mid-channel Schrödinger–Poisson calculations for transport characteristics, it is projected that these changes in stress profile together with the addition of (100)-oriented channel surfaces in the iFinFET and GAAFET affect the carrier effective mass and therefore injection velocity, enhancing the electron transport, but retarding hole transport. Combining the effect on injection velocity with the effect of improved electrostatic integrity, the GAAFET and iFinFET are each found to have a higher drive current for the same off current, relative to the bulk FinFET, with the iFinFET trading some drive current relative to the GAAFET for a substantially shorter gate stack height and simpler structure. These results suggest the iFinFET is a strong candidate for continued MOSFET scaling.
Matrix metalloproteinases in peripheral blood and cerebrospinal fluid in patients with Alzheimer's disease

ABSTRACT Background: Deposition of amyloid β in senile plaques and in cerebral blood vessels is one hallmark of the pathogenesis of Alzheimer's disease (AD). The ability of several matrix metalloproteinases (MMPs) to degrade amyloid precursor protein leading to aggregation of amyloid β, as well as the increased expression of MMPs in post mortem brain tissue of Alzheimer's patients, indicate that MMPs play an important role in the pathogenesis of AD. Methods: We investigated levels of MMP-2,-3,-9 and -10 in plasma and cerebrospinal fluid (CSF) of AD patients (n = 14) by gelatin and casein zymography. Comparisons between AD patients and controls relative to levels of MMP-2, MMP-3, MMP-9, and MMP-10 were made with Wilcoxon rank statistics. Pearson correlations were computed as measures of association. Results: MMP-3 in AD was significantly elevated in plasma (p = 0.006) and there was a trend towards increase in CSF (p = 0.05). MMP-2 in CSF of AD patients was significantly decreased (p = 0.02) while levels in plasma remained unchanged. MMP-9 and MMP-10 could not be detected in CSF; MMP-10 was unchanged in plasma, but MMP-9 was significantly decreased (p = 0.02). Conclusions: These findings constitute further evidence for the important role of MMPs in the pathogenesis of AD.
Stress, the hippocampus and the hypothalamic-pituitary-adrenal axis: implications for the development of psychotic disorders.

OBJECTIVE The experience of stress is commonly implicated in models of the onset of psychotic disorders. However, prospective studies investigating associations between biological markers of stress and the emergence of psychotic disorders are limited and inconclusive. One biological system proposed as the link between the psychological experience of stress and the development of psychosis is the Hypothalamic-Pituitary-Adrenal (HPA) axis. This paper summarizes and discusses evidence supporting a role for HPA-axis dysfunction in the early phase of schizophrenia and related disorders. METHOD A selective review of psychiatric and psychological research on stress, coping, HPA-axis, the hippocampus and psychotic disorders was performed, with a particular focus on the relationship between HPA-axis dysfunction and the onset of psychotic disorders. RESULTS Individual strands of past research have suggested that the HPA-axis is dysfunctional in at least some individuals with established psychotic disorders; that the hippocampus is an area of the brain that appears to be implicated in the onset and maintenance of psychotic disorders; and that an increase in the experience of stress precedes the onset of a psychotic episode in some individuals. Models of the onset and maintenance of psychotic disorders that link these individual strands of research and strategies for examining these models are proposed in this paper. CONCLUSIONS The current literature provides some evidence that the onset of psychotic disorders may be associated with a higher rate of stress and changes to the hippocampus. It is suggested that future research should investigate whether a relationship exists between psychological stress, HPA-axis functioning and the hippocampus in the onset of these disorders. Longitudinal assessment of these factors in young people at 'ultra' high risk of psychosis and first-episode psychosis cohorts may enhance understanding of the possible interaction between them in the early phases of illness.
Coronally advanced flap procedure for root coverage. Is flap thickness a relevant predictor to achieve root coverage? A 19-case series.

This clinical study was designed to determine whether the thickness of the flap can influence root coverage when gingival recessions associated with traumatic toothbrushing are treated using a coronally advanced flap (CAF). Nineteen patients, aged from 25 to 57 years, with high levels of oral hygiene (full-mouth plaque scores <20%) were selected for the study. Each patient contributed with one Miller Class I or II maxillary or mandibular recession. A total of 19 recessions > or =2 mm were treated. After local anesthesia and before flap elevation, the exposed root surface was planed with a sharp curet. A trapezoidal full- and partial-thickness flap was then elevated, displaced coronally, and sutured to cover the treated root surface. Before suturing, flap thickness was measured in the alveolar mucosa with a gauge. After surgery, all patients were recalled for control and professional prophylaxis once a week during the first month and monthly up to the third month. The mean initial recession depth was 3.0+/-0.9 mm. Mean flap thickness (FT) was 0.7+/-0.2 mm. Three months later, mean recession depth was 0.6+/-0.6 (P <0.0001) and mean recession reduction was 2.4+/-0.7 mm. Mean root coverage was 82+/-17%. Flap thickness >0.8 mm was associated with 100% of root coverage. The results of this study indicate that there is a direct relation between flap thickness and recession reduction (P <0.0001).
Low‐Temperature Plasticity in Olivine: Grain Size, Strain Hardening, and the Strength of the Lithosphere

Plastic deformation of olivine at relatively low temperatures (i.e., low‐temperature plasticity) likely controls the strength of the lithospheric mantle in a variety of geodynamic contexts. Unfortunately, laboratory estimates of the strength of olivine deforming by low‐temperature plasticity vary considerably from study to study, limiting confidence in extrapolation to geological conditions. Here we present the results of deformation experiments on olivine single crystals and aggregates conducted in a deformation‐DIA at confining pressures of 5 to 9 GPa and temperatures of 298 to 1473 K. These results demonstrate that, under conditions in which low‐temperature plasticity is the dominant deformation mechanism, fine‐grained samples are stronger at yield than coarse‐grained samples, and the yield stress decreases with increasing temperature. All samples exhibited significant strain hardening until an approximately constant flow stress was reached. The magnitude of the increase in stress from the yield stress to the flow stress was independent of grain size and temperature. Cyclical loading experiments revealed a Bauschinger effect, wherein the initial yield strength is higher than the yield strength during subsequent cycles. Both strain hardening and the Bauschinger effect are interpreted to result from the development of back stresses associated with long‐range dislocation interactions. We calibrated a constitutive model based on these observations, and extrapolation of the model to geological conditions predicts that the strength of the lithosphere at yield is low compared to previous experimental predictions but increases significantly with increasing strain. Our results resolve apparent discrepancies in recent observational estimates of the strength of the oceanic lithosphere.
The Future of Small Farms in Asia

type="main" xml:id="dpr12159-abs-0001"> Farms throughout Asia are predominantly small. By nature, small farms use labour-intensive production methods. The question arises as to the viability of small farms in the face of the rapidly increasing wage rate in most Asian countries. There is also indication that the production efficiency of small farms has declined relative to large farms in many Asian economies, indicating the increasing disadvantage of small farms in Asia. Therefore, this study argues that unless new policy measures are taken to expand farm size, Asia as a whole is likely to lose comparative advantage in agriculture and become an importer of food grains in the future.
Education in electric and electronic engineering via students involvement in innovative projects

The promotion of the students' transversal or generic competencies is one of the key points of the new European educational framework. Today, companies hiring graduate students are not only concerned about their technical background but also transversal skills and competencies. Hence, it becomes necessary to adopt measures to promote and cultivate these competencies among students. The students' involvement in innovative research projects brings an excellent opportunity to achieve this goal: competence dimensions as team work, effective oral and written communication, effective use of informational resources, independent learning, foreign language, problem resolution among many other can be effectively developed by involving students in multidisciplinary teams conceived to develop this type of projects. This paper focuses on this idea, remarking the usefulness of these projects to achieve the goals pursues by the new educational framework in the context of generic competencies. A real success story at the Universitat Politecnica de Valencia, based on a project relying on the development of an intelligent hardware system (SEE4ME) is presented. It confirms the ability of this approach to promote generic skills and competencies among students.
Considerations for powering a clinical proteomics study: Normal variability in the human plasma proteome

Proteomics is increasingly being applied to the human plasma proteome to identify biomarkers of disease for use in non‐invasive assays. 2‐D DIGE, simultaneously analysing thousands of protein spots quantitatively and maintaining protein isoform information, is one technique adopted. Sufficient numbers of samples must be analysed to achieve statistical power; however, few reported studies have analysed inherent variability in the plasma proteome by 2‐D DIGE to allow power calculations. This study analysed plasma from 60 healthy volunteers by 2‐D DIGE. Two samples were taken, 7 days apart, allowing estimation of sensitivity of detection of differences in spot intensity between two groups using either a longitudinal (paired) or non‐paired design. Parameters for differences were: two‐fold normalised volume change, α of 0.05 and power of 0.8. Using groups of 20 samples, alterations in 1742 spots could be detected with longitudinal sampling, and in 1206 between non‐paired groups. Interbatch gel variability was small relative to the detection parameters, indicating robustness and reproducibility of 2‐D DIGE for analysing large sample sets. In summary, 20 samples can allow detection of a large number of proteomic alterations by 2‐D DIGE in human plasma, the sensitivity of detecting differences was greatly improved by longitudinal sampling and the technology was robust across batches.
Paper-cutting Image Retrieval Technology based on LSH Improvement

Characteristics of paper-cutting, paper-cutting gallery construction, etc. are analyzed aiming at existing problems of folk traditional paper-cutting art multimedia interactive platform. It is proposed that rotation invariant LBP (Local Binary Pattern) is combined with LSH algorithm to present a large-scale paper-cutting image fast retrieval method. Firstly, the background image is eliminated with OTSU, then the paper-cutting image rotation LBP feature. In addition, highdimensional data is mapped to low dimensional space, and a hash index was constructed by local sensitive hash algorithm to find the approximate KNN. Experimental result in the dataset shows that the improved algorithm has high accuracy on paper-cutting image retrieval, and it is significantly higher than traditional algorithm on retrieval speed.
A Light guide plate based flexible optical cuff for optogenetic stimulation of motor units

This paper reports a light guide plate based flexible optical cuff for optogenetic stimulation of motor units. We propose the optical cuff based on a single-sheet PDMS light guide plate (LGP). It has good flexibility, and can be improved the efficiency of the light source by distributing the light globally through the LGP. Moreover, the possibility of cell necrosis due to heat can help to reduce by preventing direct contact between the μ-LED and neurons.
Development of the Persian version of the Vertigo Symptom Scale: Validity and reliability

Background: Vertigo Symptom Scale (VSS) is a proper instrument for assessing the patient status, clarifying the symptoms, and examining the relative impact of the vertigo and anxiety on reported handicap. Our aim is the translation and cross-cultural adaptation of the VSS into Persian language (VSS-P) and investigating its validity and reliability in patients with peripheral vestibular disorders. Materials and Methods: VSS was translated into Persian. Cross-cultural adaptation was carried out on 101 patients with peripheral vestibular disorders and 34 participants with no history of vertigo. They completed the Persian versions of VSS, dizziness handicap inventory (DHI), and Beck anxiety inventory (BAI). Internal, discriminant, and convergent validities, internal consistency, and test-retest reliability were determined. Results: The VSS-P showed good face validity. Internal validity was confirmed and demonstrated the presence of two vertigo (VSS-VER) and autonomic-anxiety (VSS-AA) subscales. Significant difference between the median scores for patient and healthy groups was reported in discriminate validity (P <0.001). Convergent validity revealed high correlation between both BAI and DHI with VSS-P. There was a high test-retest reliability; with intraclass correlation coefficient of 0.89, 0.86, and 0.91 for VSS-AA, VER, and VSS-P, respectively. The internal consistency was good with Cronbach's alpha 0.90 for VER subscale, 0.86 for VSS-AA subscale, and 0.92 for the overall VSS-P. Conclusion: The Persian version of the VSS could be used clinically as a valid and reliable tool. Thus, it is a key instrument to focus on the symptoms associated with dizziness.
Probing the Interaction of SR141716A with the CB1 Receptor*

Background: SR141716A binds the CB1 receptor selectively and exerts inverse agonist activity. Results: We identify a key role of the minor binding pocket for SR141716A binding. Conclusion: SR141716A exerts inverse agonist activity by securing the Trp rotameric switch, restraining CB1 from activation. Significance: This is the first reported molecular description of the superimposition of SR141716A- and CP55940-binding sites. SR141716A binds selectively to the brain cannabinoid (CB1) receptor and exhibits a potent inverse agonist/antagonist activity. Although SR141716A, also known as rimonabant, has been withdrawn from the market due to severe side effects, there remains interest in some of its many potential medical applications. Consequently, it is imperative to understand the mechanism by which SR141716A exerts its inverse agonist activity. As a result of using an approach combining mutagenesis and molecular dynamics simulations, we determined the binding mode of SR141716A. We found from the simulation of the CB1-SR141716A complex that SR141716A projects toward TM5 to interact tightly with the major binding pocket, replacing the coordinated water molecules, and secures the Trp-3566.48 rotameric switch in the inactive state to promote the formation of an extensive water-mediated H-bonding network to the highly conserved SLAXAD and NPXXY motifs in TM2/TM7. We identify for the first time the involvement of the minor binding pocket formed by TM2/TM3/TM7 for SR141716A binding, which complements the major binding pocket formed by TM3/TM5/TM6. Simulation of the F1742.61A mutant CB1-SR141716A complex demonstrates the perturbation of TM2 that attenuates SR141716A binding indirectly. These results suggest SR141716A exerts inverse agonist activity through the stabilization of both TM2 and TM5, securing the Trp-3566.48 rotameric switch and restraining it from activation.