Miracle-dz/UniFAR-FTUs huggingface dataset:
Preparation of Enantiomerically Pure (S)-(-)-1-(1'-naphthyl)-ethanol by the Fungus Alternaria alternata.

(S)-(-)-1-(1'-napthyl)-ethanol (S-NE) is an important intermediate for the preparation of mevinic acid analogs, which is used for the treatment of hyperlipidemia. The objectives of the study were to isolate a microorganism that could effectively reduce 1-acetonaphthone (1-ACN) to S-NE, to determine the influence that the physicochemical parameters would have on the reduction by the isolated microorganism, and to attempt large-scale studies with the microorganism. Over the years fungi have been considered a promising biocatalyst and it has been presumed that many fungal species have not been isolated and therefore the current study focused on possible isolation of these microorganisms. A total of 72 fungal isolates were screened for their ability to reduce 1-ACN to its corresponding alcohol. The isolate, EBK-62, identified as Alternaria alternata, was found to be the most successful at reducing the ketone to the corresponding alcohol in the submerged culture. The reaction conditions were systematically optimized for the reducing agent A. alternata EBK-62, which showed high stereospecificity and good conversion for the reduction. The preparative scale study was carried out in a 2 L bioreactor and a total of 4.9 g of S-NE in optically pure form (>99% enantiomeric excess) was produced in 48 h. Chirality 28:669-673, 2016. © 2016 Wiley Periodicals, Inc.
Basket CMS Derivatives in Term Structure Market Models with Stochastic Volatility

We consider the pricing of Caps and Floors on CMS baskets in term structure models. To this end we shortly review CMS indices and the market for financial products based on these indices.Having specified the financial products we review two popular Stochastic Volatility Libor Market Model frameworks for pricing interest rate derivatives and show how to derive (semi-) analytical pricing formulas within these frameworks. The stochastic volatility is of Heston or SABR type.Our proposed methods do not only allow the fast pricing of basket CMS Caps and Floors but they can also be applied to calibrate the market models by taking into account market quotes for CMS and CMS spread options.
Resurrection from Bunkers and Data Centers

The bunker is a securitized storage space that bodies, objects, and materialized information enter in defense against anticipated threat. The mountain or cliff cave was humanity’s prehistoric bunker – a geological gift of sanctuary – where our ancestors lived, stored food, and buried their dead. Bunker development, from excavation and underground construction, co-evolved with agricultural sedentarism to protect grain, living people, and stored riches, with these bunkers always outliving their harboured artifacts, and the people who built them. Conceptualisation of these spaces thus lies at the intersection between the materiality of the bunker and temporality of its contents, though scholarly attention has been drastically weighted toward the former.
A Simplified Colorimetric Test for Poliomyelitis Virus and Antibody∗

Summary Under the particular experimental conditions developed and herein described, the production of a yellow color by dispersed HeLa cell cultures in a medium containing phenol red, is regularly prevented by un-neutralized poliomyelitis virus. Thus, a simplified method is available for titration of the poliomyelitis viruses and their type-specific antibodies.
The Australian Coral Reef Fin-Fish Fishery ITQ Market

The Australian coral reef fin-fish fishery (CRFFF) on the Great Barrier Reef has been managed under ITQs since 2004. A large number of different reef species (>155) are covered by the management plan, but the primary species in terms of value and volume landed are coral trout and red throat emperor. All remaining species are classified as other species for management purposes. The operational side of the fishery is relatively heterogeneous and distinct sub-divisions exist between participants in terms of individual vessel characteristics and the species and product forms landed. The ITQ system has introduced an additional dimension for heterogeneity between fishers whilst also allowing investors not participating in the fishery to hold and trade quota. This analysis uses data on individual level quota holdings and trades to assess the CRFFF quota market and its evolution through time. Fishery level trends in ownership and trade are determined, and market participants are identified as belonging to one out of a set of seven generalized types. The emergence of groups such as investors and lease dependent fishers is clear. In 2010-11 42% of coral trout quota was owned by participants that did not fish it and 69% of total coral trout landings were made by fishers that owned only 11% of the quota. The incentives faced by the groups within the fishery differ, as do their vulnerabilities and resilience to natural or management related changes in the fishery's situation.
UK investment analyst reaction to window dressing of financial statements: a laboratory experiment

This thesis is primarily concerned with the reaction of UK investment analysts when confronted with window dressed financial statements and its implications for stock market information processing and efficiency. Three associated empirical examinations are undertaken. 1) A detailed investigation of the prevalence of window dressing in UK company accounts and the nature of such exercises is conducted using a random sample of 100 sets of accounts for large UK corporates. A substantial degree of window dressing is identified. The analysis is developedfurther to explore the relationship between extent of window dressing and financial position of the firm although the results are ambiguous. 2) To explore the importance of accounting information generally to the investment analysis community, relative to alternative sources, and the manner in which it is used to drive investment recommendations a detailed content analysis of a large sample of stockbroker circulars is conducted. The results suggest the importance of accounting information for market participants may be conventionally overstated. Nonetheless the statistical findings, although significant, are not very strong which may partially reflect the heterogeneity found in the methods used by different stockbroking firms in appraising shares. Further work is required. 3) The main part of the thesis reports on a laboratory experiment with 63 experienced stockbroking analysts drawn from five of the top City houses. The analysts were required to process company accounts and adjust for window dressed items. We were forced to conclude that, at least at the time, the research took place in early 1990, investment analysts were neither very concerned by nor able or inclined to correct for creative accounting. These findings are discussed in detail and implications for different market theories drawn. The theories conclude that there may well be valid concerns about the conventional role attributed to investment analysts as information intermediaries in maintaining market efficiency, particularly in the processing of and disseminating complex accounting information.
Paths of molecular excitation.

The intramolecular pathways for electronic excitation are described in terms of orbital type of excitation, and multiplicity of the states involved, with the consideration of the kinetic and quantal requirements on the transitions between excited states. For most molecules studied, it is appropriate to classify the lower energy-excited states into two broad groups, those involving only plus or minus -electron excitation ( plus or minus , plus or minus * states), and those involving lone-pair or nelectron (nonbonding) excitation to plus or minus -antibonding orbitals (n, plus or minus * states). When the oscillator strengths are oonsidered, and the nature of spin-orbital effects is taken into account, the predominance of singlet-singlet luminescence for molecules with lowest ( plus or minus , plus or minus *) singlet excited states, and the uniqueness of the triplet-singlet luminescence for molecules with lowest (n, plus or minus *) singlet excited states can be understood. The application to photochemical and radiationchemical studies are discussed, with an indication of the need for such studies on biologioally important molecules. 39 references. (auth)
Relocation of Congenitally Elevated Scapula

Summary: In the treatment of Sprengel's deformity, extraperiosteal greenstick fracture of the clavicle in conjunction with surgical release of all attachments between the scapula and the spine provides an easy, safe method of relocating the scapula to its normal level. The improved position is maintained by temporary fixation of the inferior border of the scapula to the eighth rib with slowly resorbable sutures. Section of the coracoclavicular ligaments, excision of the superior pole of the scapula, and suture fixation of the medial angle of the scapula to the spinous process of the fourth vertebra enables the procedure to be performed on patients until the age of puberty. This surgical technique has been performed in 28 consecutive patients with Sprengel's deformity, aged 4 to 19 years, without any neurovascular complications. A normal scapular position was achieved in 67% of cases, 1 to 2 cm elevation in 29%, and 5 cm in 4%.
Role of Adrenergic Receptors in Veratridine-Stimulated Amylase Secretion from Rabbit Pancreatic Lobules

Sympathetic inhibition of pancreatic enzyme secretion has been attributed to vasoconstriction and direct inhibition of acinar cells. We observed both adrenergic inhibition and facilitation of cholinergic transmission in rabbit pancreatic ganglia, which innervate acini. Here we used pancreatic lobules to determine whether adrenergic receptors also regulate synaptic transmission between pancreatic nerves and acini. Stimulation of pancreatic nerve terminals with veratridine (Ver), an activator of voltage-dependent Na+ channels, resulted in a 102% increase in amylase secretion, which was unaffected by &agr; and &bgr; receptor antagonists but inhibited 65% by atropine. At a concentration of 10 &mgr; M, norepinephrine inhibited (38%) and epinephrine potentiated (40%) Ver-stimulated secretion. At the same concentration, the &agr;2 agonist clonidine (Clon) inhibited (39%), whereas the nonselective &bgr; agonist isoproterenol (Iso) and the selective &bgr;3 agonist BRL 37344 potentiated (71 and 67%, respectively) nerve-stimulated secretion. The effects of Clon and Iso and BRL 37344 were antagonized by yohimbine and propranolol, respectively. Phenylephrine, dobutamine, and terbutaline had no effect. Neither basal, bethanechol-stimulated, nor noncholinergic nerve-stimulated secretion was significantly altered by Clon or Iso. Thus, cholinergic nerve terminals innervating pancreatic acini exhibit both inhibitory &agr;2 and atypical facilitatory &bgr; adrenergic receptors. The apparent lack of adrenergic innervation suggests that adrenergic receptors on the nerve terminals of cholinergic pancreatic neurons are under hormonal control by circulating catecholamines. These results provide further evidence that intrinsic pancreatic neurons, which supply most, if not all, of the cholinergic innervation of acini, are important sites of sympathetic regulation of pancreatic exocrine secretion.
Creative Publishing or Fad: The Case of Transplant Registry Analyses

The development of health policies strongly relies on analyses of reports from national registries that are required and controlled by the federal government, such as the UNOS (United Network for Organ Sharing) or USRDS (US Renal Data System). [The phlethora of information generated by an academic milieu stimulated by the dictum ‘publish or perish’ comprised a large number of meta and registry analyses of different values, even with contradictory results. ] The academic milieu eager to ‘publish rather than perish’ has contributed a large number of meta analyses or registry analyses of different significances, even with contradictory results. This case regards an analysis of the hepatitis C antibody status outcome among the renal transplant recipient population that was published in two peer-review journals reporting on almost the same patients, with a 43% overlap between the two transplant registries (1,2).
The role of U.S. timberland in real estate portfolios

Timberland is seen as a long-term investment which has recently received increased institutional investor attention in many countries and potentially provides added value in a mixed-asset portfolio. Using the National Council of Real Estate Investment Fiduciaries (NCREIF) timberland series, this paper analyses the risk-adjusted performance and portfolio diversification benefits of timberland in the United States over the period of 1987-2007. U.S. timberland is seen to have been a strongly performed asset class with significant portfolio diversification benefits over this period; with a significant portfolio role separate to that of real estate. However, recent years have seen reduced risk-adjusted returns, with some loss of portfolio diversification benefits of timberland with stocks and real estate. Global drivers are likely to see increased future demand for timberland investment.
Doğrudan Yabancı Sermaye Yatırımları Ve Türkiye

Bu calismada Dogrudan Yabanci Sermaye Yatirimlari ve Turkiye ekonomisi acisindan gelismeler analiz edilmeye calisilmistir Dogrudan Yabanci Sermaye Yatirimlarinda onemli gelismeler ulkemiz acisindan agirlikli olarak 2000 sonrasi donemde yasanmistir Bu nedenle calismamizda 2000 sonrasi donemde giren ve cikan Dogrudan Yabanci Sermaye Yatirimlari analiz edilmektedir Gunumuz dunyasinda Dogrudan Yabanci Sermaye Yatirimlarinin yonelimi onemli olcude hizmetler sektorune dogru gelisme gostermektedir Son donemlerde ulkemize gelen yatirimlarin daha cok ozellestirmeler sirket birlesmeleri ve gayrimenkul alimi gibi alanlarda yogunlasmasi dunyadaki bu egilimle paralellik gostermektedir Turkiye’nin yurtdisi yatirimlarinda ise sanayi sektorunun onemi devam etmekte ve hizmetler sektorune yapilan yatirimlar kadar onemli oldugu gozlenmektedir
CULTURAL ASPECTS OF BUSINESS & IT ALIGNMENT

Aligning IT to business needs is still one of the most important concerns for senior management. The message of Business & IT Alignment (BIA) is logical and undisputed, but implementation apparently difficult. As part of a research program on the differences between the theory and practice of BIA this paper explores the impact of (national) cultures on the maturity of BIA. The paper relies on Hofstede’s framework of cultural dimensions (Hofstede, 1980) to understand the concept of culture. We present a compact literature review on the influence of culture on IT that leads to the conclusion that there is an influence and that it is likely that also alignment of business and IT will be affected by cultural aspects. After a brief introduction we than analyze this influence by conceptually assessing the potential impact of Hofstede’s cultural dimensions on the variables of BIA maturity.
Production of Angiotensin-I-Converting-Enzyme-Inhibitory Peptides in Fermented Milks Started by Lactobacillus delbrueckiisubsp. bulgaricus SS1 and Lactococcus lactissubsp. cremoris FT4

ABSTRACT Two fermented milks containing angiotensin-I-converting-enzyme (ACE)-inhibitory peptides were produced by using selectedLactobacillus delbrueckii subsp. bulgaricus SS1 and L. lactis subsp. cremoris FT4. The pH 4.6-soluble nitrogen fraction of the two fermented milks was fractionated by reversed-phase fast-protein liquid chromatography. The fractions which showed the highest ACE-inhibitory indexes were further purified, and the related peptides were sequenced by tandem fast atom bombardment-mass spectrometry. The most inhibitory fractions of the milk fermented by L. delbrueckii subsp.bulgaricus SS1 contained the sequences of β-casein (β-CN) fragment 6-14 (f6-14), f7-14, f73-82, f74-82, and f75-82. Those from the milk fermented by L. lactis subsp.cremoris FT4 contained the sequences of β-CN f7-14, f47-52, and f169-175 and κ-CN f155-160 and f152-160. Most of these sequences had features in common with other ACE-inhibitory peptides reported in the literature. In particular, the β-CN f47-52 sequence had high homology with that of angiotensin-II. Some of these peptides were chemically synthesized. The 50% inhibitory concentrations (IC50s) of the crude purified fractions containing the peptide mixture were very low (8.0 to 11.2 mg/liter). When the synthesized peptides were used individually, the ACE-inhibitory activity was confirmed but the IC50s increased considerably. A strengthened inhibitory effect of the peptide mixtures with respect to the activity of individual peptides was presumed. Once generated, the inhibitory peptides were resistant to further proteolysis either during dairy processing or by trypsin and chymotrypsin.
Valuation of options and corporate liabilities with interest rate uncertainty

Successful record producing financial research as a financial engineer in a business environment or as a finance faculty member. Adept at managing technical staff, including building extremely strong research teams at Citibank, First Chicago, Bankers Trust and Morgan Stanley. These teams have always contributed at the frontier of financial knowledge on Wall Street while keeping a strong practical bent in their effort. Strong experience in teaching graduate and undergraduate courses in Finance as a full time faculty member or adjunct. Academic accomplishments include publication of several papers in refereed journals and technical books. Business accomplishments include development of key risk management systems at Citibank and First Chicago, significant product and strategy innovations at Lehman Brothers and Bankers Trust, trading desk and business development at CIBC and improvements in the VaR system and the counterparty risk management system of Morgan Stanley.
A Critical Review of Gender in South Korea's Official Development Assistance

Abstract This paper critically examines the gender aspects of South Korea's Official Development Assistance (ODA) with a focus on its legal and policy framework, financial and human resource input, using data on ODA activities from 1991 and 2006 to the present based on KOICA and OECD's gender marked data, respectively. Gender equality is an important cross-cutting issue for poverty reduction through women's empowerment in developing countries. It is also recognized by the OECD and other international organizations as being key to enhancing aid effectiveness. The OECD pointed out in its Special Review on South Korea's ODA, conducted in 2008, that South Korea has not paid much attention on cross-cutting issues, particularly gender equality. This paper concludes that although the South Korean government has made some progress toward enhancing gender issues in its ODA policy framework and guidelines, major challenges remain in emphasizing the significance of gender among its various ODA-related ministries and implementation agencies. There is no consistently holistic approach to gender in government and its actual implementation, as reflected in aid projects, different sectors, types of aid, and the organizational structure of ODA.
The mechanism of silver staining of proteins separated by SDS polyacrylamide gel electrophoresis

Abstract Gel based silver staining of proteins is thought to occur by selective reduction of silver ions to insoluble metallic silver at specific initiation sites in the vicinity of the protein molecules. Silver stained protein bands generally are dark brown or black with considerable variation in color intensity. The color variation has been attributed to diffractive scattering by silver grains of different sizes. Our experiments, however, demonstrate that color variation is due to the formation of silver chromate deposits that are incorporated into formalin fixed proteins. Understanding the mechanism of silver staining is essential for developing a method for protein quantification.
Structural and photophysical properties of heterobimetallic 4f-zn iminophenolate cryptates.

Lanthanide complexes with the Schiff base axial macrobicyclic ligand L(1) react with Zn(II) nitrate in the presence of CaH(2) to yield Ln(III)-Zn(II) heterodinuclear cryptates with the formula [Ln(NO(3))(L(1)-3H)Zn](NO(3)). xH(2)O.yMeOH. The macrobicyclic receptor L(1) is an azacryptand N[(CH(2))(2)N=CH-R-CH=N-(CH(2))(2)](3)N (R = 1,3-(2-OH-5-Me-C(6)H(2))). The crystal structures of the Pr(III), Yb(III), and Lu(III) complexes, chemical formulas [Ln(NO(3))(L(1)-3H)Zn](NO(3)). xSolv (monoclinic, C2/c, Z = 8), as well as that of [Zn(2)(L(1)-3H)](NO(3)). H(2)O (15) (triclinic, P(-)1, Z = 2), have been determined by X-ray crystallography. The ligand is helically wrapped around the two metal ions, leading to pseudo-C(3) symmetries around the metals. The Ln(III)-Zn(II) distances lie in the range 3.3252(13) to 3.2699(14) A, while the Zn(II)-Zn(II) distance in 15 amounts to 3.1037(18) A. The three five-membered chelate rings of the ligand backbone coordinating the Ln(III) ion adopt a (lambdalambdadelta)(5) (or (deltadeltalambda)(5)) conformation while the three pseudochelate rings formed by the coordination of the ligand to the Zn(II) ion adopt a (lambda'lambda'lambda')(5) (or (delta'delta'delta')(5)) conformation. Thus in the solid state the conformation of the three cations is Lambda(deltadeltalambda)(5)(delta'delta'delta')(5) or its enantiomeric form Delta(lambdalambdadelta)(5)(lambda'lambda'lambda')(5). In solution, the helicates present a time-averaged C(3) symmetry, as shown by (1)H NMR, and the conformation of the cations is described as Lambda(deltadeltadelta)(5)(delta'delta'delta')(5) (or Delta(lambdalambdalambda)(5)(lambda'lambda'lambda')(5)). The photophysical properties of the cryptates depend on the nature of the Ln(III) ion, and (L-3H)(3)(-) is revealed to be a good sensitizer for Eu(III) and Tb(III) at low temperatures, but the emission at room temperature is limited by the low energy of the ligand (3)pipi state. While Eu(III) is most effectively sensitized by the ligand triplet state, the Tb(III) ((5)D(4)) sensitization occurs via the singlet state. The quantum yield of the metal-centered luminescence in the Eu-Zn cryptate amounts to 1.05% upon ligand excitation. The low energy of the ligand (3)pipi state allows efficient sensitization of the Nd(III) and Yb(III) cryptates, which emit in the near-infrared.
Acquisition systems for GNSS signals with the same code and bit rates

In this paper we address the problem of the acquisition of GNSS signals for the next-generation systems (as Galileo, and GPS modernization), which will use signals with code rate equal to the bit rate. In this case there is a potential sign transition in each segment of the signal processed in the acquisition schemes. The search space could result greatly impaired, especially with the methods based on FFT. These methods are very efficient, but a bit transition leads to a modification of the shape of the Cross Ambiguity Function evaluated in the search space. Here we propose a method which mitigates this impairment, which fits the requirements of the new GNSS signals. We will show that the bit transition does not destroy the information on the presence of the satellite, but introduces an error in the estimation of the Doppler frequency and code delay. In fact the effect of the sign transition on the correlation peak is a splitting of the peak into two asymmetric lobes along the correct delay bin, so leading to a potential null value at the correct cell. However the integral of these lobes exhibits an invariance property, which can be exploited to recover the bit transition position, from which the acquisition process becomes feasible. In the paper we will provide the mathematical background of a method based on this invariance property and we will show some simulation results which prove the validity of the method.