Miracle-dz/UniFAR-FTUs huggingface dataset:
Identification-Based Closed-Loop Control Strategies for a Cylinder Wake Flow

Four closed-loop control strategies are discussed to reduce the drag of a cylinder wake flow: Linear Quadratic Gaussian (LQG) control, gain-scheduled LQG (GS-LQG) control, gain-scheduled PI control, and multimodel predictive control (M-MPC). The control models are obtained in an input–output framework through ARMAX (for LQG control), multi-ARMAX (for GS-LQG control and M-MPC), and multi-ARX (for gain-scheduled PI control). The use of system identification for the underlying flow control problem gets rid of the difficult task of developing accurate and robust reduced-order models for the Navier–Stokes (NS) equations. The control is introduced through sucking of fluid through the cylinder surface. The drag on the cylinder is reduced for all control methods. The robustness of all control strategies is tested against unmodeled disturbances and/or dynamics through a detailed simulation of an NS equation-based model by varying in time the Reynolds number around its nominal value 200. For the considered cylinder wake, the M-MPC approach is the best solution. The application of the presented closed-loop control algorithms for the cylinder drag control as a benchmark problem constitutes promising solutions for other related flow control problems in industries.
An Evaluation of the Bumby RAPE and MOLEST Scales as Measures of Cognitive Distortions with Civilly Committed Sexual Offenders

Cognitive distortions are commonly viewed as an important factor in the assessment and treatment of sexual offenders. However, consensus about the operational definition of cognitive distortions and the best instrument to measure such distortions is lacking. This paper evaluates the Bumby MOLEST and RAPE scales as measures of cognitive distortions with patients civilly committed under California's Sexually Violent Predator law. Rapists and child molesters in the current sample endorsed markedly fewer cognitive distortions than the sexual offenders in Bumby's original study (K. M. Bumby, 1996). It is suggested that current self-report measures such as the MOLEST and RAPE scales are too susceptible to a socially desirable response set to provide useful data with sexual offenders who are involuntarily committed for treatment.
Preference Dynamics in Sequential Consumer Choice with Defaults

This research examines the impact of defaults on product choice in sequential-decision settings. Whereas prior research has shown that a default can affect what consumers purchase by promoting choice of the preselected option, the influence of defaults is more nuanced when consumers make a series of related choices. In such a setting, consumer preferences may evolve across choices due to “spillover” effects from one choice to subsequent choices. The authors hypothesize that defaults systematically attenuate choice spillover effects because accepting a default is a more passive process than either choosing a nondefault option in the presence of a default or making a choice in the absence of a default. Three experiments and a field study provide compelling evidence for such default-induced changes in choice spillover effects. The findings show that firms’ setting of high-price defaults with the aim of influencing consumers to choose more expensive products can backfire through the attenuation of spillover. In addition to advancing the understanding of the interplay between defaults and preference dynamics, insights from this research have important practical implications for firms applying defaults in sequential choices.
Do Linguistic Structures Affect Human Capital? The Case of Pronoun Drop

This paper empirically studies the human capital effects of grammatical rules that permit speakers to drop a personal pronoun when used as a subject of a sentence. By de‐emphasizing the significance of the individual, such languages may perpetuate ancient values and norms that give primacy to the collective, inducing governments and families to invest relatively little in education because education usually increases the individual's independence from both the state and the family and may thus reduce the individual's commitment to these institutions. Carrying out both an individual‐level and a country‐level analysis, the paper indeed finds negative effects of pronoun‐drop languages. The individual‐level analysis uses data on 114,894 individuals from 75 countries over 1999‐2014. It establishes that speakers of such languages have a lower probability of having completed secondary or tertiary education, compared with speakers of languages that do not allow pronoun drop. The country‐level analysis uses data from 101 countries over 1972‐2012. Consistent with the individual‐level analysis, it finds that countries where the dominant languages permit pronoun drop have lower secondary school enrollment rates. In both cases, the magnitude of the effect is substantial, particularly among females.
Isolation of a Polyvalent Bacteriophage for Escherichia coli, Klebsiella pneumoniae, and Aerobacter aerogenes

A lytic bacteriophage isolated from sewage was found to attack strains of Aerobacter aerogenes, Escherichia coli, and Klebsiella pneumoniae, but not members of the genera Salmonella, Proteus, and Serratia. The phage, designated φmp, contained deoxyribonucleic acid with a 50% guanine plus cytosine ratio and a molecular weight of 23.1 × 106 daltons. Single-step growth experiments of φmp plated at 37 C on A. aerogenes A2 gave a mean latent period of 20 min, an average burst size of 103 plaque-forming units/infected cell, and an average adsorption rate constant of 3 × 10−10 ml/min. Electron microscopy of φmp revealed a phage with a flexible tail (165 nm long and 6 nm wide). The phage head had a hexagonal outline (62 nm in diameter).
Testosterone and cardiovascular disease risk

Purpose of reviewAgeing is accompanied by a reduction in circulating testosterone and progressive accumulation of medical morbidities. There is an intense debate whether low testosterone contributes to ill-health as opposed to being a biomarker for its presence. Prescriptions for testosterone are rising on a background of concern over potential adverse effects. This review examines evidence relating androgens to cardiovascular risk in older men. Recent findingsObservational studies show lower risk of cardiovascular events in older men with higher testosterone, and lower mortality from ischaemic heart disease in men with higher concentrations of its more potent androgenic metabolite dihydrotestosterone. However, randomized controlled trials of testosterone supplementation have been underpowered for the outcome of cardiovascular events. Recent meta-analyses have reached contrasting conclusions regarding cardiovascular adverse events associated with testosterone therapy. Retrospective studies of prescription databases have produced controversial and conflicting results. SummaryAdditional randomized controlled trials are required to clarify the role of testosterone supplementation in older men in the absence of pituitary or gonadal disease. Pending such studies, testosterone therapy should be considered in androgen-deficient men, with evaluation of potential benefits and risks.
The quality movement from six perspectives

Purpose The purpose of this paper is to examine the quality movement in the framework of an organizing taxonomy model from six perspectives: global trend, national mandate, industry trend, organizational strategy, operational strategy, and personal philosophy. Design/methodology/approach The authors use the organizing taxonomy model to analyze the quality movement from each of the six perspectives in terms utilizing a diverse range of key questions, characteristics, and issues which must be addressed. Findings The analysis shows that viewing the quality movement from these various perspectives can help practitioners in developing an understanding of the quality movement not only from a historical standpoint, but also in terms of current requirements and future demands. This can also benefit quality management researchers in terms of organizing the focus of their research on the various perspectives. The organizing taxonomy model can also be used to assess other phenomena such as lean, supply chain management, knowledge management, and business analytics which are similarly impacting organizations across all industries and throughout the world. Originality/value The paper presents a fresh look at the quality movement from a range of perspectives and provides insight into an organized method of assessing major movements that continue to impact businesses globally.
Key Features of Governance in Brazilian Science and Technology Parks

The situation of Brazilian Science and Technology Parks (STPs) operation led to the field research. Even with the public policy of stimulus and support of associations, nothing has been mapped on the dissemination of results (economic growth and regional development). This scenario instigates the question: What are the governance characteristics of Brazilian Science and Technology Parks? A empirical field research was developed, taking into consideration the possibility of replication trought the registration of the choice criteria in the multiple cases and trought research detalhes and data colection. Eight STPs (TECNOPUC - Porto Alegre, Valetec - Novo Hamburgo, Tecnosinos - Sao Leopoldo, Unicamp, CIATEC and TECHNOPARK - Campinas, Rio Park - Rio de Janeiro and SergipeTec) participated in research. The results and considerations about the research question allows to infer the little effectiveness of governance (without qualitative or quantitative performance indicators) is possibly caused by tensions characterized by elements such as heterogeneity in characteristics of organizations that are part of STPs, lack of consensus on common goals, pressure forces and influences affecting trusts, nonconformity standards and personal and organizational preferences. Leadership relations championed by the government and / or companies can negatively influence the STP's performance as a whole.
Strategies to successfully recruit and engage clinical nurses as participants in qualitative clinical research

Background: Research conducted in the clinical area promotes the delivery of evidence-based patient care. Involving nurses as participants in research is considered essential to link patient care with evidence-based interventions. However recruitment is influenced by nurses’ competing demands and understanding engagement strategies may assist future research. Aim: This reflective analysis aimed to understand influencing factors and strategies that support successful recruitment nurses in clinical research. Method: A reflective analysis of research notes and focus group data from research with oncology nurses was completed. Results: This research identified that gaining support from key staff, understanding work constraints and developing a rapport with nurses is important. Establishing clear relevance and benefits of the research and being flexible with research requirements enabled nurses to participate in the research. Conclusion: Clear information and a willingness to accommodate the demands and dynamic nature of the environment, ensures ongoing support and engagement of nurses in the clinical setting as participants in research.
Investigating pulmonary embolism in the emergency department with lower limb plethysmography: the Manchester Investigation of Pulmonary Embolism Diagnosis (MIOPED) study

Objectives: To measure the diagnostic accuracy of computerised strain gauge plethysmography in the diagnosis of pulmonary embolism (PE). Methods: Two researchers prospectively recruited 425 patients with pleuritic chest pain presenting to the emergency department (ED). Lower limb computerised strain gauge plethysmography was performed in the ED. All patients underwent an independent reference standard diagnostic algorithm to establish the presence or absence of PE. A low modified Wells’ clinical probability combined with a normal D-dimer excluded PE. All others required diagnostic imaging with PIOPED interpreted ventilation perfusion scanning and/or computerised tomography (CT) pulmonary angiography. Patients with a nondiagnostic CT had digital subtraction pulmonary angiography. All patients were followed up clinically for 3 months. Results: The sensitivity of computerised strain gauge plethysmography was 33.3% (95% confidence interval (CI) 16.3 to 56.2%) and specificity 64.1% (95% CI 59.0 to 68.8%). The negative likelihood ratio was 1.04 (95% CI 0.68 to 1.33) and positive likelihood ratio 0.93 (95% CI 0.45 to 1.60). Conclusions: Lower limb computerised strain gauge plethysmography does not aid in the diagnosis of PE.
MANAGER’S PERSONALITY AND BUSINESS MODEL INNOVATION

Rapid changes in the external environment and dynamic markets have challenged the survival of every kind of organizations. Many business firms fail due to lack of managerial skills and an ineffective business model to adjust their operations in line with the competitive environment. This study examines the influence of owners and top managers’ “Big Five” personality traits on business model innovation. Data were collected through structured questionnaires using a sample size of 343 owners and senior managers of SMEs operating in the emerging economy Pakistan. Hypotheses were tested using structural equation modeling (SEM) in AMOS.21. The results indicate that managers with extroversion, agreeableness, and openness to experience personality have a significant positive influence on business model innovation. However, neuroticism personality has a significant negative while conscientiousness has an insignificant positive influence on business model innovation. Implications for practice are also discussed.
Thromboelastography and Cardiopulmonary Bypass

The TEG tracks postoperative hemorrhage after CPB and is useful in guiding therapy. Its ability to characterize the overall interaction of all procoagulant participants in a final outcome (clot strength) is unique. Much work in the future is needed to establish the particular applications for TEG monitoring in CPB patients
Surgical versus medical treatment for secondary post‐partum hemorrhage

Background. Secondary post‐partum hemorrhage (PPH) is defined as any abnormal bleeding from the birth canal occurring between 24 hours and 12 weeks postnatally. Treatment usually falls into one of the two categories: surgical evacuation of the uterus or medical treatment. Objective. To compare the two different clinical approaches and the implications on future fertility. Study design. A retrospective study. Setting. From 1990 to 2002, 168 women diagnosed with late PPH were admitted to the Hadassah Medical Centers in Jerusalem. The cases were divided into two groups according to the planned initial treatment: primary surgical treatment vs. primary medical treatment. Results. Primary surgical treatment was associated with significantly more primary negative events (p = 0.01). After the primary event, primary surgical treatment was associated with fewer future deliveries (p = 0.04) and resulted in increased rate of secondary infertility of borderline significance (p = 0.06). Conclusions. Our results show that secondary PPH is related to high rates of immediate and long‐term complications. It is possible that a conservative medical approach for secondary PPH may be superior to surgical treatment.
Combining numerous gyroscopes for accuracy improvement using autoregressive process for rate signal modeling

A signal processing technique for gyro array is presented in this paper to reduce noise and improve the accuracy of micro-electro-mechanical system (MEMS) gyroscope. To improve the dynamic performance, the true rate is modeled by an autoregressive (AR) model instead of a random walk. According to the analysis results of the Allan variance, the measurement model is simplified and a mathematical model is established. Based on this model, a novel Kalman filter (KF) with modified estimation process for combining outputs of a gyroscope array is designed. The performance and the affect factors of the gyro array are analyzed by using a steady-state covariance. The experimental results indicate that the RMSE of the gyroscopes can be reduced from 0.4925 deg/s to 0.0034 deg/s by an array composed of six gyroscopes in static test. The dynamic test is also discussed and the validity of the proposed modeling and fusion method is proved.
Lactoferrin upregulates the expression of CD4 antigen through the stimulation of the mitogen‐activated protein kinase in the human lymphoblastic T Jurkat cell line

The main biological properties of lactoferrin are thought to concern inflammation and immunomodulation processes, including maturation of immature B and T cells. Lactoferrin accelerates T‐cell maturation by inducing the expression of the CD4 surface marker. In this report, using the Jurkat T‐cell line, we have shown that lactoferrin upregulates the expression of CD4 antigen through the activation of a transduction pathway. Using an anti‐phosphotyrosine antibody, lactoferrin was demonstrated to induce a cascade of phosphorylation of numerous proteins on their tyrosine residues. This tyrosine‐phosphorylation was transient, reaching maxima between 5 and 10 min. We also identified the mitogen‐activated protein kinase (MAP kinase) which presented an enhanced catalytic activity, reaching a maximum at 10 min of incubation with lactoferrin. Moreover, the use of inhibitors such as genistein and PD98059, tyrosine kinases and MAP kinase kinase (or MEK) inhibitors respectively, allowed us to correlate the activation of MAP kinase with the upregulation of CD4 expression. Finally, using Lck‐defective Jurkat cells, our results showed that the p56lck (Lck) kinase is necessary for MAP kinase activity and CD4 expression. This paper demonstrates that lactoferrin activates transduction pathway(s) in lymphoblastic T‐cells, and that Lck and the Erk2 isoform of MAP kinase are implicated in the upregulation of CD4, induced by lactoferrin in these cells. J. Cell. Biochem. 79:583–593, 2000. © 2000 Wiley‐Liss, Inc.
[Two scales for job stress and psychological health investigation: type-A personality and job satisfaction].

PURPOSE The purpose of the present study is to investigate the psychometric properties of two instruments developed to measure Type-A behaviors and job satisfaction, two important variables mentioned in the stress literature. METHOD The data were collected from two different samples, one composed of 426 bank personnel, the other composed of 94 adults working in a private company. The findings are presented separately under the titles Study I and Study II. In both of the studies the assessment instruments used were: Stress Audit (Symptoms), Stress Audit (Vulnerability), Stress Coping Behaviors, Job Satisfaction Scale, and Type-A Behaviors Inventory. RESULTS For both of the instruments, the studies were based on factor analyses. For Type-A Behaviors Inventory the analyses revealed 4 factors, while for Job Satisfaction Scale they revealed 6 factors. The factor subscales developed from these factors were found to have satisfactory Cronbach's alphas. For Type-A Behaviors Inventory they ranged between . 40 and . 90; whereas for Job Satisfaction Inventory these values were between . 53 and . 94. Both studies also included correlational analyses to specify the criterion validity values of the two instruments. CONCLUSION The findings revealed that both of the instruments had satisfactory psychometric values, indicating that they can be reliably used in health psychology and job stress studies.
Routine conventional karyotyping of lymphoma staging bone marrow samples does not contribute clinically relevant information

Bone marrow (BM) evaluation is an important part of lymphoma staging, which guides patient management. Although positive staging marrow is defined as morphologically identifiable disease, such samples often also include flow cytometric analysis and conventional karyotyping. Cytogenetic analysis is a labor‐intensive and costly procedure and its utility in this setting is uncertain. We retrospectively reviewed pathological reports of 526 staging marrow specimens in which conventional karyotyping had been performed. All samples originated from a single institution from patients with previously untreated Hodgkin and non‐Hodgkin lymphomas presenting in an extramedullary site. Cytogenetic analysis revealed clonal abnormalities in only eight marrow samples (1.5%), all of which were positive for lymphoma by morphologic evaluation. Flow cytometry showed a small clonal lymphoid population in three of the 443 morphologically negative marrow samples (0.7%). Conventional karyotyping is rarely positive in lymphoma staging marrow samples and, in our cohort, the BM karyotype did not contribute clinically relevant information in the vast majority of cases. Our findings suggest that karyotyping should not be performed routinely on BM samples taken to stage previously diagnosed extramedullary lymphomas unless there is pathological evidence of BM involvement by lymphoma. Am. J. Hematol. 90:529–533, 2015. © 2015 Wiley Periodicals, Inc.
The operational profile in software reliability engineering: an overview

Provides an overview of a step-by-step approach for developing the operational profile used in software reliability engineering. The operational profile can help guide managerial and engineering decisions throughout the product life cycle, including requirements specification, design, implementation and testing. It is particularly valuable in guiding test planning and testing. The development and use of this profile typically involves product and market managers and systems engineers. It is used by software developers and managers, system test planners and testers, and quality assurance and reliability engineers. The presented material has been drawn from experience in developing operational profiles for a variety of applications. <<ETX>>
Elevated Levels of Psychophysiological Arousal and Cortisol in Patients With Somatization Syndrome

Objective This study investigates psychological and psychobiological processes in patients with somatization syndrome. Method We compared physiological measures (heart rate, finger pulse volume, electrodermal activity, electromyography), cortisol levels, and subjective well-being during rest and during a mental stress task as well as selective attention and memory for illness-related words in 58 patients with somatization syndrome and 21 healthy controls. Results The somatization group had higher morning salivary cortisol concentrations, higher heart rates, and lower levels of finger pulse volume. During the mental stress task, patients with somatization syndrome felt more distressed and had higher heart rates, whereas controls showed habituation to the experimental situation. We were unable to demonstrate an attention or memory bias specific for somatization. Conclusions The results point to several psychological, psychophysiological, and psychobiological mechanisms that might be involved in the maintenance of somatization syndrome. These results are discussed from a cognitive-psychobiological perspective.