Miracle-dz/UniFAR-FTUs huggingface dataset:
AUC analysis of centralized cooperative-MIMO spectrum sensing over generalized fadec reporting channel

In this paper, a novel closed form expressions for the area under the receiver operating characteristic curve (AUC) of an energy detector is measured over generalized fading channel in terms of computable Meijer G-function. We consider the reporting channel in the Multiple-Input Multiple-Output (MIMO) based centralized cooperative spectrum sensing is experiencing a κ — μ fading channel. We assume an Additive White Gaussian (AWGN) as a sensing channel. In the reporting network, each secondary user (SU) and fusion center (FC) is equipped with multiple antenna. We consider the FC has Maximum Ratio combiner (MRC) to estimate received signal from SU and an energy detector to make the decision. The arrived low complex Meijer G-function analytical expression of AUC over generalized fading channel delivers the different conventional fading parameters of all reporting channels, also it is generalized for MIMO scenario. The derived analytical expressions of the AUC are validated by numerical computations over generalized channel with various multiple antenna scenario.
Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function

TNFα levels are elevated in the marrows of patients with myelodysplastic syndrome (MDS) and are associated with high rates of apoptosis, which contributes to hematopoietic failure. We observed that exposure of human marrow stroma cell lines HS5 and HS27a to TNFα increases levels of IL-32 mRNA. IL-32, in turn, induces TNFα. Marrow stroma from patients with MDS expressed 14- to 17-fold higher levels of IL-32 mRNA than healthy controls. In contrast, cells from patients with chronic myelomonocytic leukemia (CMML) expressed only one tenth the level of IL-32 measured in healthy controls. Human KG1a leukemia cells underwent apoptosis when cocultured with HS5 stromal cells, but knockdown of IL-32 in the stromal cells by using siRNA abrogated apoptosis in the leukemia cells. IL-32 knockdown cells also showed dysregulation of VEGF and other cytokines. Furthermore, CD56+ natural killer cells from patients with MDS and CMML expressed IL-32 at lower levels than controls and exhibited reduced cytotoxic activity, which was unaffected by IL-2 treatment. We propose that IL-32 is a marrow stromal marker that distinguishes patients with MDS and CMML. Furthermore, IL-32 appears to contribute to the pathophysiology of MDS and may be a therapeutic target.
Evaluation of natural emotions using self assessment manikins

Emotion recognition in speech is an important research objective in the field of man-machine interfaces. This paper focuses on human labeling of emotions to create training data for emotion recognition systems. A three-dimensional emotion space concept is used to address the complexity of emotions in natural speech. As an evaluation tool, an iconic representation of each emotion component (self assessment manikins, SAMs) is proposed. This method is shown to be a simple and efficient means for evaluating emotions at an utterance-based segmentation level. The results show a high inter-evaluator agreement and a good reliability with the help of statistical signal modeling
Attorney and lay beliefs about factors affecting jurors' perceptions of juvenile offender culpability

Abstract We surveyed attorneys and college students to learn what factors they believe influence jurors' perceptions of juvenile offender culpability and then varied two of these factors in a simulated case to determine their actual effects on mock jurors' decisions. In Study 1, attorneys (N=30) and undergraduate mock jurors (N=47) believed that a juvenile offender's youthful (versus adult-like) appearance would mitigate jurors' ratings of juvenile culpability. Both groups believed that jurors' perceptions of juvenile crime trends would not have an impact on culpability. In Study 2, undergraduate mock jurors (N=193) read a simulated juvenile case accompanied by a photograph of a youthful versus adult-like defendant. Mock jurors who believed that juvenile crime is increasing were more likely to render guilty verdicts, but their verdicts were not affected by the juvenile's youthful appearance. Mock jurors' sentencing recommendations did not vary as a function of the juvenile's appearance or their perceptions of juvenile crime trends. Psychologists and defense attorneys may wish to emphasize the developmental immaturity of their clients to decrease their culpability to jurors, although it is unclear how large an effect this will have on verdicts and sentencing recommendations in practice.
Efficacy of sublingual misoprostol for induction of labor at term and post term according to parity and membrane integrity: a prospective observational study

Abstract Objective: To evaluate the effectiveness and safety of 25 mcg sublingual misoprostol for induction of Labor at term according to parity and membrane integrity. Methods: We conducted a prospective observational study on singleton pregnancies undergoing induction of Labor at term. Twenty-five mcg of misoprostol were administered sublingually every 4 h. Main outcomes were vaginal deliveries within 24 h, time-to-vaginal-delivery, hyper-stimulation syndrome, cesarean section rate, arterial pH< 7.0 and NICU admission rate. Results: We studied 508 patients, 375 nulliparous and 133 multiparous women. Sixty-five percent and 78%, respectively, delivered vaginally within 24 h from first administration. Median time-to-vaginal-delivery was significantly shorter in PROM than in women with intact membranes (p < 0.001). Epidural analgesia prolonged time-to-vaginal-delivery among nulliparous women (p < 0.0005). A positive correlation between BMI and time to delivery was observed in both nulliparous and multiparous women (p < 0.05). Cesarean section rate was 22% in nulliparous and 6% in multiparous group. Induction failure was 1.4% and uterine hyper-stimulation 1%. No pH≤ 7.00 was recorded; overall 7 (1.4%) newborns were admitted to NICU. Conclusions: Sublingually administered misoprostol is an effective and safe method for induction of Labor at term. Parity, status of membranes and BMI significantly affect time to delivery.
Length Perception by Dynamic Touch under Dual-Task Conditions

We examined perceivers' ability to perceive the lengths of hand-held rods under dual-task conditions. Participants used magnitude estimation to report the whole (tip-to-tip) and partial (from the point of grasp to the forward tip) lengths of rods held in one hand. At the same time, participants had to perform with the other hand a rhythmic-aiming task of varying difficulty. The results indicated that haptically perceived length was relatively unaffected by dual-task conditions, although there were hints of a mild dual-task effect: Perceptual performance was slightly better when participants held the to-be-perceived rod still, as opposed to when they actively wielded it. The results of this research are important for understanding how people are able to divide attention in order to interact with hand-held tools while performing concurrent tasks.
Contradictory aspects of family leisure: Indealization versus experience

Abstract The idealization of family leisure in today's society directs attention towards the positive aspects of family participation and obscures less positive outcomes. This study examines the extent to which parental ideals about the value and benefits of family leisure match up to the reality of their actual experiences. Thirty‐one families with at least one child in the 10‐ to 12‐year age group took part in the study, which involved family leisure diaries as well as semistructured interviews with parents and children. Analysis showed that, although there was a relatively high level of participation in family activities, the parents were not satisfied with the amount of time devoted, nor the quality of some of the activities. A gap between parental ideals and reality was also evident in their discussions of positive and negative experiences of family leisure. Parents reacted to this gap with feelings of guilt, efforts to do more, and a resultant mix of satisfaction and frustration. While family leisure can be beneficial in a number of ways, the idealization of family time may be reinforcing the contradictory nature (i.e., the positive‐negative aspects and the idealization‐experiential gap) of this form of leisure practice, and exacerbating the burden and sense of responsibility felt by parents.
On the intersection theory of Quot schemes and moduli of bundles with sections

Abstract We consider a class of tautological top intersection products on the moduli space of stable pairs consisting of vector bundles together with N sections on a smooth complex projective curve C. We show that when N is large, these intersection numbers can equally be computed on the Grothendieck Quot scheme of coherent sheaf quotients of the rank N trivial sheaf on C. The result has applications to the calculation of the intersection theory of the moduli space of semistable bundles on C.
Evolutionary diversifications of plants on the Qinghai-Tibetan Plateau

The Qinghai-Tibetan Plateau (QTP) is the highest and one of the most extensive plateaus in the world. Phylogenetic, phylogeographic, and ecological studies support plant diversifications on the QTP through multiple mechanisms such as allopatric speciation via geographic isolation, climatic oscillations and divergences, pollinator-mediated isolation, diploid hybridization and introgression, and allopolyploidy. These mechanisms have driven spectacular radiations and/or species diversifications in various groups of plants such as Pedicularis L. , Saussurea DC. , Rhododendron L. , Primula L. , Meconopsis Vig. , Rhodiola L. , and many lineages of gymnosperms. Nevertheless, much work is needed toward understanding the evolutionary mechanisms of plant diversifications on the QTP. Well-sampled biogeographic analyses of the QTP plants in the broad framework of the Northern Hemisphere as well as the Southern Hemisphere are still relatively few and should be encouraged in the next decade. This paper reviews recent evidence from phylogenetic and biogeographic studies in plants, in the context of rapid radiations, mechanisms of species diversifications on the QTP, and the biogeographic significance of the QTP in the broader context of both the Northern and Southern Hemisphere biogeography. Integrative multidimensional analyses of phylogeny, morphological innovations, geography, ecology, development, species interactions and diversifications, and geology are needed and should shed insights into the patterns of evolutionary assembly and radiations in this fascinating region.
Themed issue: Plans, norms, motivation, and cheating a little – The curious case of healthy eating

Take John, a 30-year-old executive manager at a reception who is grabbing mindlessly from the bowl of peanuts that are being served. John loves snacking but he is also concerned about maintaining his current normal weight. Nevertheless, he finds himself indulging in the peanuts when attending to networking instead of his weight goal. Or take Mary, a secretary who pays attention to her weight because she has gained a couple of pounds and wants to fit again in the expensive pair of designer jeans she bought last year. Although she is committed to her weight goal, she finds herself eating too much when her friends convince her that just a little piece of birthday cake would not hurt.
Quantitative determination of oLAb titers in various animal species

It is generally accepted, that lipid peroxidation plays a pathogenic role in atherosclerosis. Furthermore, recent studies indicate that antibodies directed against oxidative modifications of Low Density Lipoprotein (oLAb) contribute to atherosclerotic processes and may have some function in other disorders. These antibodies have been determined predominantly in humans, because assays for oLAb measurement use species specific anti IgG conjugates. From such assay designs it is not possible to get directly comparable data from various animal species. Main advantages of comparable data between animal species are that results of animal experiments can be interpreted using human calibrators and that results of immunisations and production of monoclonal antibodies are directly comparable not only within, but also between animal species. The aim of this study was to find a modification for ELISAs for oLAb determination, which allows to measure sera of various animal species simultaneously.
Can Dance Exergames Boost Physical Activity as a School-Based Intervention?

BACKGROUND Children need opportunities to have physical activity (PA). Using exergames could be a feasible and acceptable way to boost PA in middle schools. Our goal was to increase PA by 40 minutes per week and to determine how much time, if any, was spent in moderate-to-vigorous PA (MVPA). SUBJECTS AND METHODS Eighty-four middle school youth were in a pilot study for 20 weeks: half in the Generation Fit (GenFit) intervention group and half in the control group. The GenFit group played the exergame for the first 10 weeks (Session 1), and the control group joined from 10 to 20 weeks (Session 2). The main outcome was exergaming time per student per week. RESULTS Fifty-eight students completed the pilot after 26 youth at School C were excluded for administrative reasons. Of those remaining, 40 students at School A and 18 students at School B, the average age of the sample was 13.7 years (SD=0.6), and average body mass index percentile was close to 70. During Session 1, the average dance time per child was 49 minutes per week, versus 54 minutes per week in Session 2. Mean body mass index percentile decreased by 5.6 for children who participated in GenFit, compared with 0.2 for children in the control group. At end point, accelerometers showed over half of the dance time was spent in MVPA. Qualitative data showed that most children found the exergame acceptable. CONCLUSIONS A dance exergame in middle schools offered opportunities for PA. About half of the exergame time was spent in MVPA. Exergames may be feasible and acceptable in middle schools to boost PA, and access could provide a way for schools to support the health of students.
Distribution and Evolution of the Xylanase GenesxynA and xynB and Their Homologues in Strains ofButyrivibrio fibrisolvens

ABSTRACT The ruminal bacterium Butyrivibrio fibrisolvens is being engineered by the introduction of heterologous xylanase genes in an attempt to improve the utilization of plant material in ruminants. However, relatively little is known about the diversity and distribution of the native xylanase genes in strains of B. fibrisolvens. In order to identify the most appropriate hosts for such modifications, the xylanase genotypes of 28 strains from the three 16S ribosomal DNA (rDNA) subgroups of Butyrivibrio fibrisolvens have been investigated. Only 4 of the 20 strains from 16S rDNA group 2 contained homologues of the strain Bu49xynA gene. However, these four xynA-containing strains, and two other group 2 strains, contained members of a second xylanase gene family clearly related to xynA (subfamily I). Homologues of xynB, a second previously described xylanase gene from B. fibrisolvens, were identified only in three of the seven group 1 strains and not in the group 2 and 3 strains. However, six of the group 1 strains contained one or more members of the two subfamilies of homologues of xynA. The distribution of genes and the nucleotide sequence relationships between the members of the two xynA subfamilies are consistent with the progenitor of all strains of B. fibrisolvens having contained a xynA subfamily I gene. Since many xylanolytic strains of B. fibrisolvens did not contain members of either of the xynA subfamilies or of the xynBfamily, at least one additional xylanase gene family remains to be identified in B. fibrisolvens.
Large-Scale Visualization of Sparse Matrices

An efficient algorithm for parallel acquisition of visualization data for large sparse matrices is presented and evaluated both analytically and empirically. The algorithm was designed to be application-independent, i.e., it works with any matrix-processors mapping and with any sparse storage format/scheme. The empirical scalability study of the algorithm was carried on using multiple modern HPC systems. In our largest experiment, we utilized 262,144 processors for 73 seconds to gather and store to a file the visualization data for a matrix with 1.17x10^13 nonzero elements. Using the proposed algorithm, one can thus visualize large sparse matrices with a minimal runtime overhead imposed on executed HPC codes.
Sub-chronic Ghrelin Receptor Blockade Attenuates Alcohol- and Amphetamine-Induced Locomotor Stimulation in Mice.

AIMS Ghrelin initially emerged as a gut-brain hormone controlling food intake, meal initiation and appetite mainly via hypothalamic circuits in both rodents and humans. The findings that ghrelin receptors (GHS-R1A) are expressed in reward-related areas, including the nucleus accumbens (NAc) and ventral tegmental area (VTA), suggest that ghrelin is a novel reward regulator. Indeed, ghrelin signalling mediates the rewarding and motivational properties of addictive drugs. In addition, daily co-administration of a GHS-R1A antagonist and various addictive drugs prevents the drug-induced locomotor sensitization in rats. METHODS The present series of experiment were designed to evaluate the effect of repeated pharmacological GHS-R1A suppression on drug-induced locomotor stimulation in more detail. RESULTS We showed that sub-chronic pre-treatment of the GHS-R1A antagonist, JMV2959, attenuated the ability of acute administration of alcohol as well as of amphetamine to stimulate locomotion. However, there was no effect of sub-chronic JMV2959 treatment on locomotor activity per se or on the expression of the GHS-R1A gene (Ghsr) in the VTA or the NAc compared with vehicle treatment. In addition, sub-chronic ghrelin treatment caused a locomotor sensitization. CONCLUSIONS While previous research has pinpointed ghrelin as an appetite regulator the present study together with previous studies suggest that ghrelin signalling modulates various reward-mediated behaviours in rodents. Collectively, this suggests that the GHS-R1A could be a key target for novel treatment strategies for addiction.
Estudio de la relación entre el espacio simbólico urbano y los procesos de identidad social

ResumenEl presente trabajo describe y analiza las dimensiones simbolicas del espacio a partir de la definicion conceptual de espacio simbolico urbano. Se enfatizan especialmente las implicaciones del concepto en los procesos de identidad social asociada al entorno, asi como la necesidad de contemplar los aspectos simbolicos en el analisis de los entornos urbanos y sus implicaciones metodologicas. Asimismo se presenta una investigacion empirica centrada en un barrio de Barcelona a partir de una triple aproximacion: socio-historica (analisis documental), cuantitativa (encuesta y analisis estadistico) y cualitativa (grupos de discusion y analisis de contenido). Los resultados muestran la relevancia del barrio en la configuracion de la identidad social y el papel de determinados espacios en la configuracion y mantenimiento de dicha identidad.
SHORT NOTE: AnoBase: a genetic and biological database of anophelines

AnoBase (http://www.anobase.org) is an integrated, relational database of basic biological and genetic data on anopheline species, with a particular emphasis on Anopheles gambiae. It has been designed as an information source and research support tool for the broad vector biology community. Although AnoBase is not a primary genomic database that develops and provides tools to access the genome of the malaria mosquito, it nevertheless contains several sections that offer data of genomic interest such as in situ hybridization images, an integrated gene tool and direct online access to AnoXcel, the proteomic database of An. gambiae. Moreover, AnoBase also contains information on non‐gambiae mosquito species and a novel section on studies related to insecticide resistance.
RGS19 upregulates Nm23-H1/2 metastasis suppressors by transcriptional activation via the cAMP/PKA/CREB pathway

The Nm23 metastasis suppressor family is involved in physiological and pathological processes including tumorigenesis and metastasis. Although the inverse correlation of Nm23 level with tumor metastasis potential has been widely observed, the mechanisms that regulate the expression of Nm23 remain poorly understood. Our previous studies have revealed that Nm23-H1/2 isoforms are upregulated by RGS19, a regulator of G protein signaling (RGS) protein which accelerates the termination of Gi signals. Here, we examined the ability of RGS19 to stimulate transcriptional regulation of Nm23 by screening a panel of luciferase reporter genes. Transient and stable overexpression of RGS19 upregulated the Nm23-H1/2 protein levels and activated several transcription factors including CREB, AP-1 and SRE in HEK293 cells. Interestingly, agents that increase the intracellular cAMP level and the phosphorylation of CREB (e.g., adrenergic receptor agonist, forskolin, and cAMP analogues) upregulated the expression of Nm23-H1/2 in HEK293 cells and several cancer cell lines including A549, HeLa, MDA-MB-231, and MDA-MB-435s cells. Conversely, inhibition of protein kinase A (PKA) by H-89 suppressed the phosphorylation of CREB and reduced the expression of Nm23-H1/2. Furthermore, activation of PKA attenuated cancer cell migration in wound healing and transwell assays. Collectively, these results revealed a PKA-dependent mechanism for controlling Nm23-H1/2 expression.
Testing the Simplex Assumption Underlying the Erikson Psychosocial Stage Inventory

This study examined whether or not the Erikson Psychosocial Stage Inventory (EPSI) measured the hierarchical model of development proposed by Erikson. Over 1000 college students responded to the inventory. Using the simplex pattern, the EPSI did not measure Erikson's stages for this sample of students. An examination of the EPSI for subgroups by race and gender did not yield positive results. Possible explanations of the findings are included.
Output feedback control of an actuated lower limb orthosis with bounded input

Purpose – The purpose of this paper is the control of lower limb orthosis acting at the knee joint level for a passive rehabilitation purpose. Design/methodology/approach – A control law, based on a saturated proportional derivative controller, is proposed in order to drive the shank-foot-orthosis system along a desired trajectory. Findings – The proposed control law is tested in real time using the orthosis EICOSI of the LISSI-Laboratory. The experiments show that the proposed control law is capable of providing satisfactory trajectory tracking performance given only the knee joint angle measurement. Moreover, the control law is robust with respect to external disturbances. Originality/value – Robust control of an actuated lower limb orthosis.