Miracle-dz/UniFAR-FTUs huggingface dataset:
Experimental Comparison of Misuse Case Maps with Misuse Cases and System Architecture Diagrams for Eliciting Security Vulnerabilities and Mitigations

The idea of security aware system development from the start of the engineering process is generally accepted nowadays and is becoming applied in practice. Many recent initiatives support this idea with special focus on security requirements elicitation. However, there are so far no techniques that provide integrated overviews of security threats and system architecture. One way to achieve this is by combining misuse cases with use case maps into misuse case maps (MUCM). This paper presents an experimental evaluation of MUCM diagrams focusing on identification of vulnerabilities and mitigations. The controlled experiment with 33 IT students included a complex hacker intrusion from the literature, illustrated either with MUCM or with alternative diagrams. The results suggest that participants using MUCM found significantly more mitigations than participants using regular misuse cases combined with system architecture diagrams.
The Latin–Greek Connection

In this article, the authors make a case for teaching vocabulary in the elementary grades through a focus on the morphological structure of words, in particular English words that are derived through Latin and Greek roots and affixes. The authors present a set of engaging instructional ideas for the use of Latin and Greek derivations to teach vocabulary and provide classroom-based examples of how a morphological-based vocabulary program can be implemented and its impact on students and teachers.
The dichotomous predicament of contemporary psychology

: Algorithmic model building in artificial intelligence provides a contemporary method for explaining certain kinds of human behavior. The paranoid mode of thought and action represents a kind of pathological behavior that has been well recognized for over twenty centuries. This article describes a computer simulation model embodying a theory that attempts to explain the paranoid mode of behavior in terms of strategies for minimizing and forestalling shame-induced distress. The model consists of two parts, a parsing module and an interpretation-action module. To bring the model into contact with the conditions of a psychiatric diagnostic interview, the parsing module attempts to understand the interview input of clinicians communicating in unrestricted natural language. The meaning of the input is passed to an interpretation-action module made up of data structures and production rules that size up the current state of the interview and decide which (linguistic) actions to perform in order to fulfill the model's intentions. This module consists of an object system which deals with interview situations and a metasystem which evaluates how well the object system is performing to attain its ends. The fidelity of the simulation has been tested using Turing-like indistinguishability tests in which clinical judges attempt to distinguish the paranoid model-patient from an actual paranoid patient. Since clinicians are unable to make the relevant distinctions, the simulation is considered successful at the input-output level of functional equivalence. Issues of underlying structural equivalence and the nature of generative pattern explanations are discussed in the light of the model's potential value in guiding clinicial decisions and intervention strategies in paranoid disorders.
Anesthesia for Magnetic Resonance Imaging

The role of the anesthesiologist in the delivery of services for diagnostic and therapeutic procedures outside the operating room is everexpanding. A portion of this demand can be directly attributed to radiological technology. There are numerous procedures, such as computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), and interventional neuroradiology (INR). The focus of this chapter is on the pertinent issues and management strategies available to the anesthesiologist in the MRI suite. From the perspective of the anesthesiologist, unlike many other outside locations, the MRI environment has unique requirements. These factors, combined with the management of the patient, can create a challenging situation. While the majority of MRI patients who require care from an anesthesiologist are pediatric patients, other patient groups include the critically ill and patients who may have difficulty remaining immobile for any period of time. Overall, our expertise can make the difference between an image filled with artifact secondary to movement and an image of good quality. A definite advantage of MRI is the absence of ionizing radiation compared to other radiological imaging techniques. The safety of MRI has been examined for many years. The Food and Drug Administration classifies the MRI scanner as a class II device. The issues of safety mostly relate to the presence of ferromagnetic objects and equipment. These concerns will be discussed later in detail. No hazardous effects on human cells have been demonstrated by the magnetic fields of MRI.
Indoor direction finding of terrestrial TV signals based on total recording

We have shown that high-accuracy DOA estimation can be obtained by the use of a total recording technique which simultaneously records the output signals from the elements of a virtual array antenna and a reference antenna, representing the target signals and a high-quality reference signal, and performing a correlation analysis of these signals. The method proposed in this paper enables two-branch recording of the target signals and the reference signal. By adopting two-dimensional virtual array measurement, we obtained an angular spectrum in full range of 0°–360°. Outdoor measurements were first performed to investigate the validity of the proposed measurement method. The results confirmed its effectiveness in determining DOAs very accurately. We then investigated the system performance in an indoor environment, which is the ultimate objective of this study. The angular spectrum obtained showed five arriving waves, and allowed determination of the angular profile and the wave propagation structure. In conclusion, we have had a very accurate measurement tool for indoor propagation.
Cerebrospinal fluid biomarkers for neuropsychological symptoms in early stage of late-onset Alzheimer's disease

Purpose: In addition to testing blood, cerebrospinal fluid (CSF) has been analyzed in the search for biomarkers. The aim of this study was to identify biomarkers in CSF for neuropsychological symptoms in early-stage late-onset Alzheimer's disease (LOAD). Methods: CSF levels of beta-amyloid 1-42 (Aβ42), F2-isoprostanes (F2-IsoPs) and F4-neuroprostanes (F4-NPs) were assayed in nine patients with mild Alzheimer's disease (AD), nine patients with amnestic mild cognitive impairment (a-MCI) and nine individuals with normal mental function. The three groups underwent neuropsychological testing. Results: CSF levels of F2-IsoPs and F4-NPs did not significantly differ among the three groups. Aβ42 in CSF was significantly higher in the control group compared with the mild AD group (p < 0.001) and a-MCI group (p = 0.03). There was a significant positive correlation between the level of F2-IsoPs and Aβ42 in the a-MCI group and between the level of F2-IsoPs and F4-NPs in the mild AD group. In comparisons between the mild AD group and a-MCI group combined, the cognitive impairment (CI) group, with the control group, the median levels of F2-IsoPs and F4-NPs were significantly higher in the CI group and median level of Aβ42 was significantly lower in the CI group. Both the levels of F2-IsoPs and Aβ42 were significantly negatively correlated with paranoid and delusional ideation and total score for the Behavioral Pathology in Alzheimer's Disease Scale (BEHAVE-AD). Conclusions: The findings suggest CSF levels of Aβ42 and F2-IsoPs are associated with the severity of neuropsychological symptoms.
Computing Translation Units and Quantifying Parallelism in Parallel Dependency Treebanks

The linguistic quality of a parallel treebank depends crucially on the parallelism between the source and target language annotations. We propose a linguistic notion of translation units and a quantitative measure of parallelism for parallel dependency treebanks, and demonstrate how the proposed translation units and parallelism measure can be used to compute transfer rules, spot annotation errors, and compare different annotation schemes with respect to each other. The proposal is evaluated on the 100,000 word Copenhagen Danish-English Dependency Treebank.
Self-organization of digital documents based on process-oriented relations

This paper presents a novel mechanism for self-organization of structure among documents based on process oriented relations. Process-oriented relations represent operations and temporal distance between uses of documents in users' working processes. A complex new network of process-oriented relations is rearranged as a multi-layered document network (MLDN) with a recursive hypergraph structure. The MLDN is self-organized by two kinds of autonomous agent: a document agent and a group agent. This facility provides up-to-date, easy-to-understand structure among documents, and helps users' understanding of relations between documents.
A lectin‐based gold nanoparticle assay for probing glycosylation of glycoproteins

We report a glycoanalysis method in which lectins are used to probe the glycans of therapeutic glycoproteins that are adsorbed on gold nanoparticles. A model mannose‐presenting glycoprotein, ribonuclease B (RNase B), and the therapeutic monoclonal antibody (mAb) rituximab, were found to adsorb spontaneously and non‐specifically to bare gold nanoparticles such that glycans were accessible for lectin binding. Addition of a multivalent binding lectin, such as concanavalin A (Con A), to a solution of the modified gold nanoparticles resulted in cross‐linking of the nanoparticles. This phenomenon was evidenced within 1 min by a change in the hydrodynamic diameter, DH, measured by dynamic light scattering (DLS) and a shift and increase in absorbance of the plasmon resonance band of the gold nanoparticles. By combining the sugar‐binding specificity and the cross‐linking capabilities of lectins, the non‐specific adsorption of glycoproteins to gold surfaces, and the unique optical reporting properties of gold nanoparticles, a glycosylation pattern of rituximab could be generated. This assay provides advantages over currently used glycoanalysis methods in terms of short analysis time, simplicity of the conjugation method, convenience of simple spectroscopic detection, and feasibility of providing glycan characterization of the protein drug product by using a variety of binding lectins. Biotechnol. Bioeng. 2012;109: 2240–2249. © 2012 Wiley Periodicals, Inc.
Energy efficient antenna selection for a MIMO relay using RF energy harvesting

Energy harvesting has emerged as a promising technique which helps to increase the sustainability of wireless networks. In this paper, we consider a network with a single source, single destination and a single relay equipped with multiple antennas. We develop an optimization framework that exploits the energy harvested from the source radio frequency signals with smart antenna selection schemes at the relay node. Our main target is to minimize the source power and the antennas' circuit power jointly subject to quality of service constraints on the rate. To overcome the computational complexity of the optimization problem, we propose two special case schemes, namely Fixed Source Power Antenna Selection (FSP-AS) and All Receive Antenna Selection (AR-AS). Also, we suggest two sub-optimal heuristic schemes with low complexity and compare their performance with the optimization problem solutions numerically. The simulation results show the gain of our optimal scheme in terms of energy efficiency, which can be up to 80% as compared to solutions proposed in the literature.
Personality, Career Satisfaction, and Life Satisfaction: Test of a Directional Model

A conceptual model proposing paths from personality traits to career satisfaction and life satisfaction and from career satisfaction to life satisfaction was evaluated in a field study by structural equations modeling using LISREL 8. Participants were a convenience sample of 1,352 information science professionals. An exploratory maximum likelihood common factor analysis revealed two oblique personality factors, the first comprised of extraversion, optimism, assertiveness, openness, and emotional stability and the second consisting of conscientiousness and tough-mindedness. Results indicated a good fit for a two-factor personality model showing significant links between both personality factors and career satisfaction, between the second personality factor and life satisfaction, and between career and life satisfaction. Findings are discussed in terms of comparisons to previous research, limitations, and areas for further research, with emphasis on the importance of personality in relation to career satisfaction and the relationship between career and life satisfaction.
Reversible changes in protein phosphorylation during germinal vesicle breakdown and pronuclear formation in bovine oocytes in vitro

This study examined the event of protein phosphorylation in bovine oocytes during germinal vesicle breakdown (GVBD) and formation of pronuclei following fertilisation in vitro. Immature oocytes were obtained from abattoir materials and cultured in vitro. The oocytes were labelled with [32P]orthophosphate at 3 h intervals from 0 to 12 h following maturation in culture or from 3 to 18 h following insemination. One-dimensional gel electrophoresis indicated that levels of protein phosphorylation are low prior to GVBD. However, the levels of protein phosphorylation at approximately 40 kDa, 27 kDa, 23 kDa and 18 kDa increased substantially following GVBD and then decreased gradually as maturation in culture progressed. In contrast, the levels of protein phosphorylation increased gradually in the oocytes following pronucleus formation. Further, two-dimensional gel electrophoresis indicated that the protein at approximately 18 kDa reversibly changed in the oocytes during maturation and fertilisation. These results indicate that the reversible changes of this phosphoprotein may be related to either cell cycle transition or pronucleus formation during maturation and fertilisation in bovine oocytes.
Long-term outcomes of allogeneic haematopoietic stem cell transplantation for adult cerebral X-linked adrenoleukodystrophy

The adult cerebral inflammatory form of X-linked adrenoleukodystrophy is a rapidly progressive neurodegenerative disease, as devastating as childhood cerebral adrenoleukodystrophy. Allogeneic haematopoietic stem cell transplantation has been demonstrated to provide long-term neurological benefits for boys with the childhood cerebral form, but results in adults are sparse and inconclusive. We analysed data from 14 adult males with adult cerebral adrenoleukodystrophy treated with allogeneic haematopoietic stem cell transplantation on a compassionate basis in four European centres. All presented with cerebral demyelinating lesions and gadolinium enhancement. Median age at diagnosis of adult cerebral adrenoleukodystrophy was 33 years (range 21-48 years). In addition to cerebral inflammation, five patients had established severe motor disability from adrenomyeloneuropathy affecting only the spinal cord and peripheral nerves (Expanded Disability Status Scale score ≥ 6). Eight patients survived (estimated survival 57 ± 13%) with a median follow-up of 65 months (minimum 38 months). Death was directly transplant-/infection-related (n = 3), due to primary disease progression in advanced adult cerebral adrenoleukodystrophy (n = 1), or secondary disease progression (n = 2) after transient multi-organ failure or non-engraftment. Specific complications during stem cell transplantation included deterioration of motor and bladder functions (n = 12) as well as behavioural changes (n = 8). Arrest of progressive cerebral demyelination and prevention of severe loss of neurocognition was achieved in all eight survivors, but deterioration of motor function occurred in the majority (n = 5). Limited motor dysfunction (Expanded Disability Status Scale score < 6) prior to transplantation was associated with significantly improved survival [78 ± 14% (n = 9) versus 20 ± 18%(n = 5); P < 0.05] and maintenance of ambulation (Expanded Disability Status Scale score < 7) post-transplant (78% versus 0%; P = 0.021). In contrast, bilateral involvement of the internal capsule on brain MRI was associated with poorer survival [20 ± 18% (n = 5) versus 78 ± 14% (n = 9); P < 0.05]. This study is the first to support the feasibility, complications and potential long-term neurological benefit of allogeneic haematopoietic stem cell transplantation in adult cerebral adrenoleukodystrophy. Further studies are warranted to attempt to improve outcomes through patient selection and optimization of transplantation protocols.
Molecular and Functional Analyses of the Fast Skeletal Myosin Light Chain2 Gene of the Korean Oily Bitterling, Acheilognathus koreensis

We identified and characterized the primary structure of the Korean oily bitterling Acheilognathus koreensis fast skeletal myosin light chain 2 (Akmlc2f), gene. Encoded by seven exons spanning 3955 bp, the deduced 168-amino acid AkMLC2f polypeptide contained an EF-hand calcium-binding motif and showed strong homology (80%–98%) with the MLC2 proteins of Ictalurus punctatus and other species, including mammals. Akmlc2f mRNA was highly enriched in skeletal muscles, and was detectable in other tissues. The upstream regions of Akmlc2f included a TATA box, one copy of a putative MEF-2 binding site and several putative C/EBPβ binding sites. The functional activity of the promoter region of Akmlc2f was examined using luciferase and red fluorescent protein reporters. The Akmlc2f promoter-driven reporter expressions were detected and increased by the C/EBPβ transcription factor in HEK293T cells. The activity of the promoter of Akmlc2f was also confirmed in the developing zebrafish embryo. Although the detailed mechanism underlying the expression of Akmlc2f remains unknown, these results suggest the muscle-specific expression of Akmlc2f transcript and the functional activation of Akmlc2f promoter by C/EBPβ.
A Dissociation Between Moral Judgments and Justifications

To what extent do moral judgments depend on conscious reasoning from explicitly understood principles? We address this question by investigating one particular moral principle, the principle of the double effect. Using web-based technology, we collected a large data set on individuals ' responses to a series of moral dilemmas, asking when harm to innocent others is permissible. Each moral dilemma presented a choice between action and inaction, both resulting in lives saved and lives lost. Results showed that: (1) patterns of moral judgments were consistent with the principle of double effect and showed little variation across differences in gender, age, educational level, ethnicity, religion or national affi liation (within the limited range of our sample population) and (2) a majority of subjects failed to provide justifi cations that could account for their judgments. These results indicate that the principle of the double effect may be operative in our moral judgments but not open to conscious introspection. We discuss these results in light of current psychological theories of moral cognition, emphasizing the need to consider the unconscious appraisal system that mentally represents the causal and intentional properties of human action.
MicroRNAs miR-125a and miR-125b constitutively activate the NF-κB pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20)

Constitutive activation of the NF-κB pathway is associated with diffuse large B-cell lymphoma (DLBCL) pathogenesis, but whether microRNA dysfunction can contribute to these events remains unclear. Starting from an integrative screening strategy, we uncovered that the negative NF-κB regulator TNFAIP3 is a direct target of miR-125a and miR-125b, which are commonly gained and/or overexpressed in DLBCL. Ectopic expression of these microRNAs in multiple cell models enhanced K63-linked ubiquitination of proximal signaling complexes and elevated NF-κB activity, leading to aberrant expression of its transcriptional targets and the development of a proproliferative and antiapoptotic phenotype in malignant B cells. Concordantly, genetic inhibition of miR-125a/miR-125b blunted NF-κB signals, whereas rescue assays and genetic modulation of a TNFAIP3-null model defined the essential role of the TNFAIP3 targeting on miR-125a/miR-125b-mediated lymphomagenesis. Importantly, miR-125a/mir-125b effects on TNFAIP3 expression and NF-κB activity were confirmed in a well-characterized cohort of primary DLBCLs. Our data delineate a unique epigenetic model for aberrant activation of the NF-κB pathway in cancer and provide a coherent mechanism for the role of these miRNAs in immune cell activation and hematopoiesis. Further, as miR-125b is a direct NF-κB transcriptional target, our results suggest the presence of a positive self-regulatory loop whereby termination of TNFAIP3 function by miR-125 could strengthen and prolong NF-κB activity.
Nomadic inquiry in the smooth spaces of the field: A preface

Framing this essay as a preface to a return to the field in order to collect more data for her study of the older, white southern women of her hometown, this researcher uses Laurel Richardson's (1994) concept of ''writing as a method of inquiry'' in order to revisit some of the places in which she has already done field work. By employing Deleuze and Guattari's (1980 1987) image of the nomad deterritorializing space, she revisits some of those spaces- mental space, the space of the text, and the space of theory- in order to work out of the failure of her received understanding of fieldwork and to think differently about the spaces and places in which her research takes place.
Updating relaxed K-d trees

In this work we present an in-depth study of randomized relaxed <i>K</i>-d trees. It covers two fundamental aspects: the randomized algorithms that allow to preserve the random properties of relaxed <i>K</i>-d trees and the mathematical analysis of the expected performance of these algorithms. In particular, we describe randomized update algorithms for <i>K</i>-d trees based on the split and join algorithms of Duch et al. [1998]. We carry out an analysis of the expected cost of all these algorithms, using analytic combinatorics techniques. We show that the average cost of split and join is of the form ζ(<i>K</i>) ṡ <i>n</i><sup>φ(<i>K</i>)</sup> + <i>o</i>(<i>n</i><sup>φ(<i>K</i>)</sup>), with 1 ≤ φ(<i>K</i>) < 1.561552813, and we give explicit formulæ for both ζ(<i>K</i>) and φ(<i>K</i>). These results on the average performance of split and join imply that the expected cost of an insertion or a deletion is Θ(<i>n</i><sup>φ(<i>K</i>)−1</sup>) when <i>K</i> > 2 and Θ(log <i>n</i>) for <i>K</i> = 2.