Miracle-dz/UniFAR-FTUs huggingface dataset:
Study on Effect of Internal Interdepartmental Integration on Customer Loyalty: Using Service Innovation as an Mediator

Under the advancement of technology and change of environment, enterprises should comply with environmental trends, integrate internal and external resources and competence, adopt “immediate innovation” and knowledge flow in organizations, complementary competence and immediate and smooth communication with customers in order to allow organizations to acquire external knowledge and improve innovative development to maintain sustainable competitive advantages. However, current research only focuses on organizations or consumers’ behavior instead of the combination between organizational study with consumers’ behavior. This study attempts to explore effect of Internal Interdepartmental Integration on service innovation and customer loyalty. However, for the enterprises, it is the most important for the company to improve customer value and customer loyalty through service innovation. However, at present, only researches related to organizations or consumer behaviors are conducted, there is rare research into the combination between organization level and consumer behavior, and this research tries to explore this aspect, which is the motivation and contribution of this research. This research aims to explore the relationship between “Interdepartmental Integration”, “Service Innovation” and “Customer Loyalty”, according to the analysis results, the relationship between “interdepartmental integration and service innovation” and “service innovation and customer loyalty” has a low positive correlation and it reaches significant level; it shows the relationship between “interdepartmental interaction and progressive innovation” and “interdepartmental collaboration and fundamental innovation” is significant
Lipoprotein (a) and Stroke: A Meta-Analysis of Observational Studies

Background and Purpose— The relationship between elevated lipoprotein (a) levels[Lp(a)] and stroke is controversial. We systematically reviewed the literature to determine whether Lp(a) is a risk factor for stroke. Methods— We searched MEDLINE (1966 to 2006), EMBASE (1974 to 2006), and Google scholar for articles on Lp(a) and cerebrovascular disease. From potentially relevant references retrieved, we excluded uncontrolled studies, studies of children with stroke, studies investigating carotid atherosclerosis, and studies lacking adequate data. Results— Thirty-one studies comprising 56 010 subjects with >4609 stroke events met all inclusion criteria and were included in the meta-analysis. In case-control studies (n=23 with 2600 strokes) unadjusted mean Lp(a) was higher in stroke patients (standardized mean difference, 0.39; 95% CI, 0.23 to 0.54) and was more frequently abnormally elevated (OR, 2.39; 95% CI, 1.57 to 3.63). Sensitivity analysis and meta-regression did not find any influence of study design, measurement period of Lp(a) in relationship to stroke episode, subtype, age, and sex to explain the substantial heterogeneity between studies (I2=83.7%; P<0.001). There was no evidence of publication bias. In nested case-control studies (n=3 with 364 strokes) Lp(a) was not a risk factor for incident stroke (OR, 1.04; 95% CI, 0.6 to 1.8). In prospective cohort studies (n=5 with >1645 strokes), incident stroke was more frequent in patients in the highest tertile of Lp(a) distribution compared with the lowest tertile of Lp(a) (RR, 1.22; 95% CI, 1.04 to 1.43). There was no publication bias or heterogeneity in the prospective studies (I2=0.00%; P=0.67). Conclusion— This meta-analysis suggests that elevated Lp(a) is a risk factor for incident stroke.
Big Five vs. Prosodic Features as Cues to Detect Abnormality in SSPNET-Personality Corpus

This paper presents an attempt to evaluate three different sets of features extracted from prosodic descriptors and Big Five traits for building an anomaly detector. The Big Five model enables to capture personality information. Big Five traits are extracted from a manual annotation while Prosodic features are extracted directly from the speech signal. Two different anomaly detection methods are evaluated: Gaussian Mixture Model (GMM) and One-Class SVM (OC-SVM), each one combined with a threshold classification to decide the ”normality” of a sample. The different combinations of models and feature sets are evaluated on the SSPNET-Personality corpus which has already been used in several experiments, including a previous work on separating two types of personality profiles in a supervised way. In this work, we propose the above mentioned unsupervised or semi-supervised methods, and discuss their performance, to detect particular audio-clips produced by a speaker with an abnormal personality. Results show that using automatically extracted prosodic features competes with the Big Five traits. The overall detection performance achieved by the best model is around 0.8 (F1-measure)
Heart Failure–Associated Changes in RNA Splicing of Sarcomere Genes

Background—Alternative mRNA splicing is an important mechanism for regulation of gene expression. Altered mRNA splicing occurs in association with several types of cancer, and a small number of disease-associated changes in splicing have been reported in heart disease. However, genome-wide approaches have not been used to study splicing changes in heart disease. We hypothesized that mRNA splicing is different in diseased hearts compared with control hearts. Methods and Results—We used the Affymetrix Exon array to globally evaluate mRNA splicing in left ventricular myocardial RNA from controls (n=15) and patients with ischemic cardiomyopathy (n=15). We observed a broad and significant decrease in mRNA splicing efficiency in heart failure, which affected some introns to a greater extent than others. The profile of mRNA splicing separately clustered ischemic cardiomyopathy and control samples, suggesting distinct changes in mRNA splicing between groups. Reverse transcription–polymerase chain reaction validated 9 previously unreported alternative splicing events. Furthermore, we demonstrated that splicing of 4 key sarcomere genes, cardiac troponin T (TNNT2), cardiac troponin I (TNNI3), myosin heavy chain 7 (MYH7), and filamin C,gamma (FLNC), was significantly altered in ischemic cardiomyopathy and in dilated cardiomyopathy and aortic stenosis. In aortic stenosis samples, these differences preceded the onset of heart failure. Remarkably, the ratio of minor to major splice variants of TNNT2, MYH7, and FLNC classified independent test samples as control or disease with >98% accuracy. Conclusions—Our data indicate that mRNA splicing is broadly altered in human heart disease and that patterns of aberrant RNA splicing accurately assign samples to control or disease classes.
Pelvic Drop Changes due to Proximal Muscle Strengthening Depend on Foot-Ankle Varus Alignment

Background Strengthening of hip and trunk muscles can modify pelvis and hip movements. However, the varus alignment of the foot-ankle complex (FAC) may influence the effects of muscle strengthening, due to the relationship of FAC alignment with pelvic and hip kinematics. This study evaluated the effects of hip and trunk muscle strengthening on pelvis and hip kinematics during walking, in subgroups with larger and smaller values of FAC varus alignment. In addition, this study evaluated the effects of hip and trunk muscle strengthening on hip passive and active properties, in the same subgroups. Methods Fifty-three women, who were divided into intervention and control groups, participated in this nonrandomized controlled trial. Each group was split into two subgroups with larger and smaller values of FAC varus alignment. Hip and trunk muscle strengthening was performed three times a week for two months, with a load of 70% to 80% of one repetition maximum. Before and after strengthening, we evaluated (1) pelvis and hip excursions in the frontal and transverse planes during walking, (2) isokinetic hip passive external rotator torque, and (3) isokinetic concentric and eccentric peak torques of the hip external rotator muscles. Mixed analyses of variance (ANOVAs) were carried out for each dependent variable related to walking kinematics and isokinetic measurements (α = 0.05). Results The subgroup with smaller varus alignment, of the intervention group, presented a reduction in pelvic drop after strengthening (P = 0.03). The subgroup with larger varus alignment increased pelvic drop after strengthening, with a marginal significance (P = 0.06). The other kinematic excursions did not change (pelvic anterior rotation P = 0.30, hip internal rotation P = 0.54, and hip adduction P = 0.43). The intervention group showed increases in passive torque (P = 0.002), peak concentric torque (P < 0.001), and peak eccentric torque (P < 0.001), independently of FAC alignment. These results suggest that FAC varus alignment influences the effects of strengthening and should be considered when hip and trunk muscle strengthening is used to reduce pelvic drop during walking.
Ultrafast Energy Delocalization and Electron Transfer Dynamics in 2‐Aminopurine‐Containing Trinucleotides †

The fate of electronically excited states in DNA base stacks is of tremendous importance for subsequent photochemical damage reactions in the genome. In this study we present a femtosecond broadband pump‐probe study on the adenine isomer 2‐aminopurine (Ap) incorporated into trinucleotides. After selective excitation of Ap we can monitor energy delocalization between neighboring Ap moieties as well as excited state electron transfer, depending on the sequence of the trinucleotide. Our results establish the time scale for intrastand excimer formation and reveal the lifetime of the excimer state.
Holistic Vertical Regional Proposal Network for scene text detection

Scene text detection is an important research problem in computer vision community. It has great application value in many fields. Inspired by Faster-RCNN which is a popular method for object detection, we consider to apply the Regional Proposal Network (RPN) method for scene text detection because text can be regarded as the common object. The core of RPN is to detect different sizes of objects with different sizes of anchors. However, when the RPN is applied directly, it is difficult to design many different scale anchors to meet the requirements of different sizes of text boxes. For the above reasons, we adjust the anchor settings and take advantage of vertical anchor to break the restrictions of receptive field. In addition, we refer to the multi-scale network Holistically-Nested Edge Detection (HED) which produce side-output results at different steps of the neural network. The bottom layers have a smaller receptive field, which represent the features of small text area in image. The receptive field of the high-level side-outputs is larger, and it can handle the large-size text area better. We combine the advantages of RPN and HED methods and propose a Holistic Vertical Proposal Regional Network (HVRPN) for scene text detection, and our model shows good results in ICDAR03 and ICDAR11.
Is asthma associated with exposure to smoke from a coal mine fire?

In 2014, a fire at the Hazelwood open cut coal mine (Victoria, Australia) burned for about 6 weeks. Residents of the adjacent town of Morwell were exposed to high levels of fine particulate matter (PM2.5) during this period. Three and a half years after the event, this study aimed to investigate the long-term impact of short-term exposure to coal mine fire smoke on asthma. A cross-sectional analysis was undertaken on a group of exposed participants with asthma from Morwell (n=165) and a group of unexposed participants with asthma from the control town of Sale (n=64). Town exposure status was determined by modelled PM2.5 data for the mine fire period. Respiratory symptoms were assessed with a validated respiratory health questionnaire and symptom severity score. Asthma control was assessed with an asthma control questionnaire. Lung function testing included spirometry, bronchodilator response, and fraction of exhaled nitric oxide. There was no evidence that exposed Morwell participants had more severe asthma symptoms, worse lung function, or more eosinophilic airway inflammation compared to unexposed Sale participants. However there was some evidence that Morwell participants had more uncontrolled than well-controlled asthma, compared to the participants from Sale (adjusted relative risk ratio 2.71 95%CI: 1.02, 7.21, p=0.046). Three and a half years after exposure, coal mine fire smoke does not appear to be associated with more severe asthma symptoms or worse lung function, but may be associated with poorer asthma control. Summary take home message In people with asthma, short-term coal mine fire smoke exposure does not appear to have long-term impact on severity of asthma symptoms, lung function or eosinophilic airway inflammation, but may affect asthma control.
1 WNT RECEPTORS , BONE MASS AND FRACTURES : GENE-WIDE ASSOCIATION ANALYSIS OF LRP 5 AND LRP 6 POLYMORPHISMS WITH REPLICATION

1 Department of Internal Medicine. Hospital U.M. Valdecilla-IFIMAV, University of Cantabria. RETICEF. Santander, Spain 2Research Foundation, Hospital Clínico Universitario, Valencia, Spain. 3 Service of Orthopedic Surgery and Traumatology. Hospital U.M. Valdecilla-IFIMAV, University of Cantabria. Santander, Spain. 4Department of Pediatrics, Obstetrics and Gynecology, University of Valencia, and University Hospital Doctor Peset, Valencia, Spain. 5 Unit of Legal Medicine. University of Cantabria. Santander, Spain
ARCHAEOLOGICAL PARASITES AS INDICATORS OF ENVIRONMENTAL CHANGE IN URBANIZING LANDSCAPES: IMPLICATIONS FOR HEALTH AND SOCIAL STATUS

Using archaeological data of two human intestinal parasites from seventeenth- to early twentieth-century contexts, we explore the intersection of biological and cultural variables that shaped the ecology of cities in northeastern North America during the modern period. These parasites are useful because they require a developmental period in the soil, thus providing a link between human activities and changing environments. Prior to the last decades of the eighteenth century, Trichuris eggs dominate the archaeoparasitological assemblage. Around 1800, there is a shift to increasing proportions of Ascaris eggs, which appears to be largely complete by 1850—a period of increasing urbanization in the northeast United States. Both environmental and behavioral factors play a role in this shift and include the relationship between parasite biology and changing microenvironments, attempts to deal with waste, and use of urban spaces. During this period, poorer households would likely have been at greater risk of parasites because of the ways they used yard spaces, their delayed access to sanitary technology, and the changing nature of urban vegetation in densely occupied neighborhoods. Utilizando datos arqueológicos sobre dos parásitos intestinales humanos recuperados en contextos que datan desde el siglo XVII hasta principios del siglo XX, exploramos la intersección entre las variables biológicas y culturales que dieron forma a la ecología de las ciudades en el noreste de América del Norte durante el período moderno. Estos parásitos son indicadores útiles porque requieren un período de desarrollo en el suelo, proporcionando así un vínculo entre las actividades humanas y su entorno cambiante. Antes de las últimas décadas del siglo XVIII, los huevos de Trichuris dominan el conjunto arqueo-parasitológico. Esto cambia alrededor de 1800 con un incremento en la proporción de huevos de Ascaris, aumento que parece concluir alrededor de 1850 —un período de urbanización creciente en el noreste de Estados Unidos—. Factores ambientales y comportamentales influyeron en este cambio. Estos incluyen la relación entre la biología de los parásitos y los microambientes cambiantes, las diferentes estrategias de manejos de desechos y el uso de los espacios urbanos. Durante este período es probable que los hogares más pobres estuvieran en mayor riesgo de tener parásitos debido a la forma en que se utilizaban los espacios abiertos, retrasos en el acceso a la tecnología sanitaria y la naturaleza cambiante de la vegetación urbana en los barrios densamente ocupados.
Associations Between Symptom Validity Test Failure and Scores on the MMPI–2–RF Validity and Substantive Scales

This study examined the association between Symptom Validity Test (SVT) failure and the Minnesota Multiphasic Personality Inventory–2 Restructured Form (MMPI–2–RF; Ben-Porath & Tellegen, 2008), in the Forensic Disability Claimant samples described in the MMPI–2–RF Technical Manual (Tellegen & Ben-Porath, 2008a, 2008b). SVTs used included the Word Memory Test (Green, 2003), the Computerized Assessment of Response Bias (Allen, Conder, Green, & Cox, 1997), the Medical Symptom Validity Test (Green, 2004), and the Test of Memory Malingering (Tombaugh, 1996). SVT failure was associated with significant elevations throughout the MMPI–2–RF overreporting validity scales and substantive scales. Pairwise contrasts between groups failing 0 and 3 SVTs revealed predominantly large effect sizes for the overreporting validity scales (d = 0.78–1.11), and many of the substantive scales, including the Cognitive Complaints (COG) scale. Results of this study demonstrate an association between SVT performance and elevated scores on the MMPI–2–RF. These results suggest that exaggeration of cognitive symptoms as demonstrated by SVT failure is also associated with overreported emotional, somatic, and neurocognitive complaints on the MMPI–2–RF.
The clinician's perspective on sarcoma pathology reporting: impact on treatment decisions?

Summary The current refinement of nosological classification of sarcoma which integrates molecular typing with a growing number of subtypes contrasts with the one-size-fits-all approach proposed in clinical practice guidelines for both local treatment and systemic treatment in the past. However, there is a growing proportion of sarcomas in which specific treatment strategies are proposed as standard. As a consequence, central review by expert sarcoma pathologists should be organised to ensure the optimal management of all patients. The key parameters in the pathology report influencing treatment decisions are therefore rapidly evolving. First a diagnostic biopsy, ideally an imaged guided microbiopsy performed by an experienced team, is a recommended practice. On the resection specimen, the size, histological grade, location, depth, surgical margins and tumour fragmentation are essential parameters to guide the treating physician. Molecular characterisation of the driving genomic event is becoming increasingly important for treatment decision making, in routine practice and in clinical trials. Molecular grade is a research tool with potentially high utility, and requires further evaluation and validation in prospective clinical trials.
Does Chronic Facet Pain Cause Depression in Rural Indian Population

Background: Chronic pain and major depression commonly occur together. Major depression in patients with chronic pain is associated with decreased function, poorer treatment response and increased health care costs. Purpose of the study: To estimate the prevalence of depression in persons with chronic facet pain and correlation of depression with Pain intensity and age. Method: Cross sectional Questionnaire based study. Total 80 subjects with chronic low back pain were included in the study. Out of which 40 were with diagnosis of facet pain in lumbar region and 40 with chronic low back pain of any other cause. Patients were assessed using ‘Patient Health Questionnaire 9’ (PHQ-9) and Visual analogue scale. Result: High prevalence (78.75%) of depression among chronic pain patients without any difference in chronic facet pain and chronic low back pain of any origin, there was strong relation between pain severity and depression (r=0.86). Conclusion: Our study revealed a high prevalence of depression amongst patients with chronic facet pain and chronic low back pain of any origin.
On Shift-Dependent Cumulative Entropy Measures

Measures of cumulative residual entropy (CRE) and cumulative entropy (CE) about predictability of failure time of a system have been introduced in the studies of reliability and life testing. In this paper, cumulative distribution and survival function are used to develop weighted forms of CRE and CE. These new measures are denominated as weighted cumulative residual entropy (WCRE) and weighted cumulative entropy (WCE) and the connections of these new measures with hazard and reversed hazard rates are assessed. These information-theoretic uncertainty measures are shift-dependent and various properties of these measures are studied, including their connections with CRE, CE, mean residual lifetime, and mean inactivity time. The notions of weighted mean residual lifetime (WMRL) and weighted mean inactivity time (WMIT) are defined. The connections of weighted cumulative uncertainties with WMRL and WMIT are used to calculate the cumulative entropies of some well-known distributions. The joint versions of WCE and WCRE are defined which have the additive properties similar to those of Shannon entropy for two independent random lifetimes. The upper boundaries of newly introduced measures and the effect of linear transformations on them are considered. Finally, empirical WCRE and WCE are proposed by virtue of sample mean, sample variance, and order statistics to estimate the new measures of uncertainty. The consistency of these estimators is studied under specific choices of distributions.
A graphics and vision unified processor with 0.89µW/fps pose estimation engine for augmented reality

In many ways, 3D graphics and vision processing are inverse operations. Graphics processing generates pixels from descriptors, while vision generates descriptors from pixels [1]. Since augmented reality (AR) requires both graphics and vision abilities (Fig. 18.6.1), we report a unified processor for graphics, vision, and pose estimation for marker tracking. To process both graphics and vision simultaneously, we use 4 key features: (1) 6-way VLIW datapath design of processing elements, (2) reconfigurable processing elements for graphics and vision modes, (3) a pixel arranger for vision processing that has the inverse characteristic of a graphics rasterizer, and (4) a dedicated pose-estimation engine to generate graphics control data from vision processing. Using these methods, we achieve 371.9GOPS/W for full operation in a VGA image and 0. 89µW/fps for pose estimation.
Synchronization design of a coupled phase-locked loop

Coupled phase-locked loops (CPLLs) are introduced as novel circuits for phased-array antennas. Successful implementation relies on characterizing the synchronization behavior of CPLL circuits over a broad range of circuit parameters. Considering inherent time delay in the phase-locked loop demonstrates the degradation in the pull-in and hold-in ranges, as well as circuit instabilities, suggesting circuit parameter limits in a phased-array design. We compare the theoretical limits, in the form of analytic equations and numerical simulations, with measurements of the pull-in and hold-in processes of a 1.5-GHz prototype CPLL.
Determination of local chromatin composition by CasID

ABSTRACT Chromatin structure and function are determined by a plethora of proteins whose genome-wide distribution is typically assessed by immunoprecipitation (ChIP). Here, we developed a novel tool to investigate the local chromatin environment at specific DNA sequences. We combined the programmable DNA binding of dCas9 with the promiscuous biotin ligase BirA* (CasID) to biotinylate proteins in the direct vicinity of specific loci. Subsequent streptavidin-mediated precipitation and mass spectrometry identified both known and previously unknown chromatin factors associated with repetitive telomeric, major satellite and minor satellite DNA. With super-resolution microscopy, we confirmed the localization of the putative transcription factor ZNF512 at chromocenters. The versatility of CasID facilitates the systematic elucidation of functional protein complexes and locus-specific chromatin composition.