Miracle-dz/UniFAR-FTUs huggingface dataset:
Green Supply-Chain Management: A State-of-the-Art Literature Review

There is a growing need for integrating environmentally sound choices into supply-chain management research and practice. Perusal of the literature shows that a broad frame of reference for green supply-chain management (GrSCM) is not adequately developed. Regulatory bodies that formulate regulations to meet societal and ecological concerns to facilitate growth of business and economy also suffer from its absence. A succinct classification to help academicians, researchers and practitioners in understanding integrated GrSCM from a wider perspective is needed. Further, sufficient literature is available to warrant such classification. This paper takes an integrated and fresh look into the area of GrSCM. The literature on GrSCM is covered exhaustively from its conceptualization, primarily taking a 'reverse logistics angle'. Using the rich body of available literature, including earlier reviews that had relatively limited perspectives, the literature on GrSCM is classified on the basis of the problem context in supply chain's major influential areas. It is also classified on the basis of methodology and approach adopted. Various mathematical tools/techniques used in literature vis-a-vis the contexts of GrSCM are mapped. A timeline indicating relevant papers is also provided as a ready reference. Finally, the findings and interpretations are summarized, and the main research issues and opportunities are highlighted.
Attachment and interpersonal relationships in postnatal depression

Postnatal depression (PND) is a debilitating condition that has demonstrated negative impacts on the mother, her infant, and her intimate and social relationships. Using an attachment theory perspective, this study examined the relationship of insecure working models of attachment to depression, marital quality, infant bonding, and social support in Australian samples of diagnosed depressed (n=47) and comparison (n=68) mothers. Clinically depressed mothers reported less security of attachment and more preoccupied and fearful attachment. Irrespective of diagnostic status, attachment styles characterised by a negative model of self were associated with higher depression and lower quality of relationship with baby and spouse and the perception of less social support. The role of dismissing attachment in the outcomes was less clear. The potential mutual influence of depression and attachment working models is discussed, and it is concluded that while insecure attachment working models may be associated with postnatal depression, further research using longitudinal methods and multiple attachment assessment techniques is required.
The human genome browser at UCSC.

As vertebrate genome sequences near completion and research refocuses to their analysis, the issue of effective genome annotation display becomes critical. A mature web tool for rapid and reliable display of any requested portion of the genome at any scale, together with several dozen aligned annotation tracks, is provided at http://genome.ucsc. edu. This browser displays assembly contigs and gaps, mRNA and expressed sequence tag alignments, multiple gene predictions, cross-species homologies, single nucleotide polymorphisms, sequence-tagged sites, radiation hybrid data, transposon repeats, and more as a stack of coregistered tracks. Text and sequence-based searches provide quick and precise access to any region of specific interest. Secondary links from individual features lead to sequence details and supplementary off-site databases. One-half of the annotation tracks are computed at the University of California, Santa Cruz from publicly available sequence data; collaborators worldwide provide the rest. Users can stably add their own custom tracks to the browser for educational or research purposes. The conceptual and technical framework of the browser, its underlying MYSQL database, and overall use are described. The web site currently serves over 50,000 pages per day to over 3000 different users.
Effect of polyhexanide and gentamycin on human osteoblasts and endothelial cells.

QUESTIONS UNDER STUDY Infection of total joint replacements is painful, disabling and difficult to treat because of the increasing bacterial resistance against antibiotics. In view of this, antiseptics show limited bacterial tolerance and have a broad-spectrum antimicrobial activity. However, the application of antiseptics to bone is insufficiently studied in literature. Therefore, we investigated the biocompatibility of the antiseptic polyhexanide with bone related cells and asked whether supplementation to bone cement is appropriate in the management of total arthroplasty infections. METHODS We performed an in vitro study with immortalised human foetal osteoblast cells (hFOB 1.19) and human endothelial cells (EAhy 926). The cultured cells were exposed to media containing various concentrations of gentamicin (12.5-800 microg/ml) and polyhexanide (0.0006-0.01%) for six hours. We measured the phase-contrast microscopy images, the cell viability, cell number and the alkaline phosphatase activity as a parameter for osteogenic function. RESULTS The exposure of hFOB and endothelial cells to polyhexanide showed a severe reduction of viability and cell number. Gentamicin did not have negative effects on hFOB and endothelial cell number and viability. The alkaline phosphatase activity of hFOB showed a significant decrease after exposure to polyhexanide and gentamicin. The viability and the cell number of endothelial cells seem more negatively affected by polyhexanide than the parameters of the hFOB-cells. CONCLUSIONS The exposure of human osteoblasts and endothelial cells to polyhexanide at concentrations with questionable antibacterial activity resulted in severe cell damage whereas exposure to high dosed gentamicin did not. These results raise questions as to the feasibility of using antiseptics in bone cement for the treatment of total arthroplasty infections. Further in vivo studies are necessary to show the in vivo relevance of these in vitro findings.
The use of a semiocclusive dressing reduces epidermal inflammatory cytokine expression and mitigates dermal proliferation and inflammation in a rat incisional model

Occlusive wound dressings are utilized clinically to accelerate wound healing and improve the final appearance of scars. In vivo and in vitro evidence suggests that one mechanism for this effect is maintenance of normal hydration in the epidermis, although the molecular signals remain uncharacterized. We sought to elucidate histological changes and some of the molecular signals involved in this effect in a rat model of wound semiocclusion. We utilized a rat linear incision model with surgical tape occlusion. Histological stains and quantitative real‐time PCR analysis were used to characterize the cellular and molecular effects of semiocclusion on the wound healing response. Semioccluded wounds demonstrated decreased epidermal thickness and cellularity and less mitotic epidermal activity when compared with nonoccluded control wounds. Associated dermal cellularity was similarly attenuated by semiocclusion. Finally, levels of proinflammatory cytokines interleukin‐1‐α and tumor necrosis factor‐α were significantly decreased on postoperative day 3 at the transcriptional level when compared with nonoccluded wounds. Semiocclusive wound treatments significantly decrease epidermal thickness, cellularity, mitotic activity, and dermal cellularity as well as transcriptional levels of important epidermal mediators of inflammation in a rat incisional wound model.
Bad mouthing, bad habits and bad, bad, boys: an exploration of the relationship between dyslexia and drug dependence

This was a largely exploratory attempt to consider the relationship, if such a relationship exists, between dyslexia and drug dependence. Dyslexia is popularly considered to be a disability which affects the individual's ability to read and write. However, there is a considerable body of evidence indicating that dyslexia is far more than a literacy problem. Dyslexics, particularly in adulthood, are more likely to exhibit poor capacity for memory-span tasks, issues of organisational incapacity and physical awkwardness (dyspraxia) with various coping strategies having been developed over the years, to neutralise difficulties with reading and writing. As a first step, this study sought to establish whether dyslexia is more prevalent amongst a drug treatment population than within the wider community. In addition, this study sought to examine any correlation between levels of severity in dyslexia and dependence. Finally, this study offered an opportunity for a small sample of drug users to offer their thought.
Association between asporin gene aspartic acid repeat polymorphism and osteoarthritis : an updated meta-analysis

Objective: Osteoarthritis (OA) is a common disease characterized by progressive degeneration of articular cartilage. Several studies have been performed to evaluate the association between asporin gene aspartic acid repeat (ASPN D-Repeat) polymorphism and osteoarthritis susceptibility, but produced conflicting results. Our aim is to determine whether ASPN D-repeat polymorphism is associated with susceptibility to OA. Methods: A comprehensive literature search for all relevant studies was performed. The association between ASPN D-Repeat polymorphism and OA in each ethnic group was investigated. Sensitivity analysis and publication bias test were conducted. Results: Eleven studies with 8463 participants (4842 OA patients and 3621 controls) were enrolled in this study. The combined results revealed no significant association between D13 allele and the risk of OA (D13 allele vs. other alleles combined: OR 0.939, 95% CI 0.844-1.045). Subgroup analysis stratified by ethnicity and OA site further confirmed the irrelevance. The pooled results on the associations between other alleles (D14, D15, D16 and D17, respectively) and the risk of OA were similar to those of D13 allele, no significant association was identified in the overall population or in each subgroup population. Conclusion: This meta-analysis suggested that ASPN D-repeat polymorphism is not associated with OA susceptibility. Since potential confounders could not be ruled out completely, further well-designed studies are required.
Regional Differences in Muscle Activation During Hamstrings Exercise

Abstract Schoenfeld, BJ, Contreras, B, Tiryaki-Sonmez, G, Wilson, JM, Kolber, MJ, and Peterson, MD. Regional differences in muscle activation during hamstrings exercise. J Strength Cond Res 29(1): 159–164, 2015—It is believed that regional activation within a muscle may lead to greater site-specific muscular adaptations in the activated portion of the muscle. Because the hamstrings are a biarticular muscle, it can be theorized that single-joint exercises where movement originates at the hip vs. the knee will result in differential activation of the muscle complex. The purpose of the present study was to assess electromyographic activity in the proximal and distal aspects of the medial and lateral hamstrings during performance of the stiff-legged deadlift (SLDL), a hip-dominant exercise, and the lying leg curl (LLC), a knee-dominant exercise. Ten young, resistance-trained men were recruited from a university population to participate in the study. Employing a within-subject design, participants performed the SLDL and LLC to muscular failure using a load equating to their 8 repetition maximum for each exercise. The order of performance of exercises was counterbalanced between participants so that approximately half of the subjects performed SLDL first and the other half performed LLC first. Surface electromyography was used to record mean normalized muscle activity of the upper lateral hamstrings, lower lateral hamstrings, upper medial hamstrings, and lower medial hamstrings. Results showed that the LLC elicited significantly greater normalized mean activation of the lower lateral and lower medial hamstrings compared with the SLDL (p ⩽ 0.05). These findings support the notion that the hamstrings can be regionally targeted through exercise selection. Further investigations are required to determine whether differences in activation lead to greater muscular adaptations in the muscle complex.
Widespread cytoplasmic mRNA transport in yeast: Identification of 22 bud-localized transcripts using DNA microarray analysis

Cytoplasmic mRNA localization provides a means of generating cell asymmetry and segregating protein activity. Previous studies have identified two mRNAs that localize to the bud tips of the yeast Saccharomyces cerevisiae. To identify additional localized mRNAs, we immunoprecipitated the RNA transport components She2p, She3p, and Myo4p and performed DNA microarray analysis of their associated RNAs. A secondary screen, using a GFP-tagged RNA reporter assay, identified 22 mRNAs that are localized to bud tips. These messages encode a wide variety of proteins, including several involved in stress responses and cell wall maintenance. Many of these proteins are asymmetrically localized to buds. However, asymmetric localization also occurs in the absence of RNA transport, suggesting the existence of redundant protein localization mechanisms. In contrast to findings in metazoans, the untranslated regions are dispensable for mRNA localization in yeast. This study reveals an unanticipated widespread use of RNA transport in budding yeast.
Breaking the Attrition Cycle: The Effects of Supplemental Instruction on Undergraduate Performance and Attrition.

Numerous factors appear to influence retention rates. Among these are student perception of progress toward an academic career goal [18], a high level of faculty-student interaction [2, 19], and personal counseling and academic advising programs [5, 7]. General upgrading of educational services has been suggested as an additional strategy for increasing retention [14]. In their efforts to reduce attrition, many colleges and universities now provide some form of academic support services. A well-designed learning assistance program can influence retention [9, 12]. Typical programs, however, tend to serve small numbers of students at a high per student cost. Moreover, little empirical data exists concerning the effectiveness of such programs. The purpose of this article is to describe an academic support program found to be effective in addressing the problems of student performance and attrition at an urban institution of eleven thousand students. The
Inclusive and exclusive education in Sweden: principals' opinions and experiences

To support the national and international aims of inclusion, special teacher training in Sweden was replaced in 1990 by special educator training. These special educators would supervise the teachers in their school and would not exclusively teach students. The aim of this study was to investigate what the principals of 14 municipal compulsory schools in Stockholm County thought about the organisation and realisation of special education in 1996 and 2006 respectively. According to the results, there were fewer segregated groups in these schools in 2006, but an increasing number of students were placed in segregated groups that were common to several schools or municipalities. Principals at schools with teaching teams usually saw the special educator as a coordinating and supervising resource while others preferred the special teacher function. The former approach led to a more inclusive school and the latter in the direction of exclusion.
Rare ADH variant constellations are specific for alcohol dependence.

AIMS Some of the well-known functional alcohol dehydrogenase (ADH) gene variants (e.g. ADH1B*2, ADH1B*3 and ADH1C*2) that significantly affect the risk of alcohol dependence are rare variants in most populations. In the present study, we comprehensively examined the associations between rare ADH variants [minor allele frequency (MAF) <0.05] and alcohol dependence, with several other neuropsychiatric and neurological disorders as reference. METHODS A total of 49,358 subjects in 22 independent cohorts with 11 different neuropsychiatric and neurological disorders were analyzed, including 3 cohorts with alcohol dependence. The entire ADH gene cluster (ADH7-ADH1C-ADH1B-ADH1A-ADH6-ADH4-ADH5 at Chr4) was imputed in all samples using the same reference panels that included whole-genome sequencing data. We stringently cleaned the phenotype and genotype data to obtain a total of 870 single nucleotide polymorphisms with 0< MAF <0.05 for association analysis. RESULTS We found that a rare variant constellation across the entire ADH gene cluster was significantly associated with alcohol dependence in European-Americans (Fp1: simulated global P = 0.045), European-Australians (Fp5: global P = 0.027; collapsing: P = 0.038) and African-Americans (Fp5: global P = 0.050; collapsing: P = 0.038), but not with any other neuropsychiatric disease. Association signals in this region came principally from ADH6, ADH7, ADH1B and ADH1C. In particular, a rare ADH6 variant constellation showed a replicable association with alcohol dependence across these three independent cohorts. No individual rare variants were statistically significantly associated with any disease examined after group- and region-wide correction for multiple comparisons. CONCLUSION We conclude that rare ADH variants are specific for alcohol dependence. The ADH gene cluster may harbor a causal variant(s) for alcohol dependence.
Simple Strategy to Prevent Severe Head Trauma in Judo —Biomechanical Analysis—

To determine whether the use of an under-mat has an effect on impact forces to the head in Judo, a Judo expert threw an anthropomorphic test device using the Osoto-gari and Ouchi-gari techniques onto a tatami (judo mat) with and without an under-mat. Head acceleration was measured and the head injury criterion (HIC) values with or without under-mat were compared. The use of an under-mat significantly decreased (p = 0.021) the HIC values from 1174.7 ± 246.7 (without under-mat) to 539.3 ± 43.5 in Ouchi-gari and from 330.0 ± 78.3 (without under-mat) to 156.1 ± 30.4 in Osoto-gari. The use of an under-mat simply reduces impact forces to the head in Judo. Rule changes are not necessary and the enjoyment and health benefits of Judo are maintained.
Sexual Harassment in the Workplace

The authors integrate research on the causes and consequences of sexual harassment victimization with organizational research to better understand the relationship between harassment and the work outcomes of job satisfaction, job stress, and intention to quit an organization. In doing so, the authors broaden the narrow conceptualization of organizational context that has been considered in previous research on sexual harassment. This broadened conceptualization incorporates features of modern organizational structure, including social integration, structural differentiation, decentralization, and formalization—all argued to indirectly control employees by increasing employee job satisfaction and commitment (and to ultimately increase productivity and reduce turnover). Although these features of modern organizational structure are not intended to reduce sexual harassment, the authors propose and find with a national sample of almost 6,000 employees that they have the unintended consequence of doing so. The authors also propose and find that this context-harassment linkage improves understanding of the often reported relationship between sexual harassment and job dissatisfaction, job stress, and intention to quit.
Intensive risk factor control in stroke prevention

Stroke prevention is an urgent priority because of the aging of the population and the steep association of age and risk of stroke. Direct costs of stroke are expected to more than double in the US between 2012 and 2030. By getting everything right, patients can reduce the risk of stroke by 80% or more; however, getting everything right is a tall order. Roughly in order of importance, this requires smoking cessation, maintenance of a healthy weight, a Cretan Mediterranean diet, blood pressure control, lipid-lowering drugs, appropriate use of antiplatelet agents and anticoagulants, and appropriate carotid endarterectomy and stenting. A new approach called “treating arteries instead of targeting risk factors” appears promising but requires validation in randomized trials.
Teacher Qualifications and Productivity in Secondary Schools

This study examined the relationship between observable teacher characteristics and productivity as measured by an increase in student achievement on a standardized test using a value-added approach. This analysis focused on teachers of algebra, geometry, and 11th grade English Language Arts in Arkansas. The authors generated a value-added score at the school-course level and attributed that score to each teacher of that course in the school. The authors then regressed observable teacher characteristics on the value-added measure. The authors found no evidence that teacher certification route affects student tests scores, but found that higher ability math teachers do lead to higher scores.
Formal Correctness and Stability of Dense Linear Algebra Algorithms

Abstract The Formal Linear Algebra Methods Environment (FLAME) project at UT-Austin pursues the mechanical derivation of algorithms for linear algebra operations. Rather than proving loop based algorithms correcta posteriori, a systematic methodology is employed that determines loop invar iants from a mathematical specification of a given linear alge bra operation. Algorithms and their correctness proofs are then constructively derived from this loop invariant. The process has been made mechanical via a prototype system implemented with Mathematica. Once an algorithm has been determined, a similarly systematica posteriori process is used to determine the correctness in the presence of roundof f error (stability properties) of the algorithm. In this pape r, we report progress towards the ultimate goal of full automation of the system.
Intent-based mobile backhauling for 5G networks

Intent-based networking is a major component that will transform the manner in which the SDN/NFV-enabled future network infrastructures are operated. In particular, Intent-based networking is expected to play a major role in the multi-technological and software-defined 5G systems development roadmap. In this paper, we present the design and prototype implementation of an Intent-based mobile backhauling interface for 5G networks. Finally, we report on the empirical evaluation of of the proposed Intent-based interface over a small Enterprise WLAN. We also release the entire software stack under a permissive license for academic use.
Silencing of developmental genes in Hydra.

Numerous developmental control genes have been isolated in a variety of organisms by either homology cloning or system-specific strategies. Functional genetic tests, however, are available for only a few model organisms and particularly are missing in a number of animals that occupy key positions for understanding the evolution of development and gene function. Double-stranded RNA-mediated interference (RNAi) opens a way to perform functional studies in such "nongenetic" organisms. Here we show that RNAi can be used to test the function of developmental genes in the cnidarian Hydra, a classical model for developmental studies. Introduction of double-stranded RNA corresponding to the head-specific gene ks1 caused strong depletion of ks1 transcripts. ks1 loss-of-function polyps exhibited severe defects in head formation, indicating an important role of ks1 in Hydra head development. Our results demonstrate for the first time efficient gene silencing in Hydra. RNAi provides an entry point for a variety of functional studies and a direct approach for analyzing the hierarchy of regulatory genes in Hydra, which until now has not been amenable to loss-of-function genetics.