Miracle-dz/UniFAR-FTUs huggingface dataset:
Flexible Carrier Utilization in Dense Stadium

This paper investigates dynamic spectrum resource utilization in dense stadium. The proposed scheme &#64258;exibly aggregates intra-site and inter-site resources for UEs taking into account various factors such as traf&#64257;c demand, network load condition, channel quality. Extensive simulation results are presented to validate its performance. The results may shed some light on the design and deployment of future dense stadium networks.
Shared Memory with Versioned Objects

Distributed Object Memory (DOM) is an abstraction that represents a distributed-memory system as a single shared container of language-level objects. The goal of DOM is to simplify programming of parallel applications for such systems. All accesses to shared memory are made relative to objects that reside in one or more node-local memories. For example, in Amber, a DOM system for a network of workstations, remote references are transparent at the language level and are implemented using either remote procedure call or object replication and migration. While DOM can greatly simplify distribution for many application classes, it is not well suited for all domains (parallel-scienti c codes, in particular). To address the shortcomings of DOM for such domains, we introduce Versioned DOM (VDOM). In VDOM a version number is associated with each object. Multiple versions of objects can coexist and may be cached in local memories as needed to inThis work was supported in part by the National Science Foundation under Grants No. CCR-8619663 and CCR8907666, by the Washington Technology Center, and by the Digital Equipment Corporation Systems Research Center and External Research Program. crease concurrency. Object coherence is driven by synchronization methods implicitly associated with each object. Explicit versioning is used as the basis for a memory consistency model that facilitates e cient ne-grain sharing of objects. The units of VDOM coherence are fragment objects, from which language-level objects are constructed; this fragmentation solves the false-sharing problem for language-level objects. The performance of VDOM primitives compared to standard DOM coherence is presented along with speedup results for two parallel applications implemented using VDOM.
A SINFONI integral field spectroscopy survey for galaxy counterparts to damped Lyman α systems - IV. Masses and gas flows

The circumgalactic medium (CGM) of typical galaxies is crucial to our understanding of the cycling of gas into, through and out of galaxies. One way to probe the CGM is to study gas around galaxies detected via the absorption lines they produce in the spectra of background quasars. Here, we present medium resolution and new similar to 0.4-arcsec resolution (similar to 3 kpc at z similar to 1) 3D observations with Very Large Telescope/Spectrograph for Integral Field Observations in the Near Infrared of galaxies responsible for high-N(H i) quasar absorbers. These data allow us to determine in details the kinematics of the objects: the four z similar to 1 objects are found to be rotation supported as expected from inclined discs, while the fifth z similar to 2 system is dispersion dominated. Two of the systems show sign of interactions and merging. In addition, we use several indicators (star formation per unit area, a comparison of emission and absorption kinematics, arguments based on the inclination and the orientation of the absorber to the quasar line of sight and the distribution of metals) to determine the direction of the gas flows in and out of these galaxies. In some cases, our observations are consistent with the gas seen in absorption being due to material corotating with their haloes. In the case of absorbing galaxies towards Q1009-0026 and Q2222-0946, these indicators point towards the presence of an outflow traced in absorption.
A NOVEL FULLY FAST RECOVERY EMG AMPLIFIER FOR THE CONTROL OF NEURAL PROSTHESIS

Original scientific article This paper presents a novel EMG (electromyography) fast recovery amplifier, which can be used as a neural prosthesis control interface. The basis of the proposed circuit is standard three op-amp amplifier with integrator in the negative feed-back loop of the differential amplifier. The Standard three op-amp instrumentation amplifier has been modified by introducing analog delay line between the first stage (differential input differential output amplifier) and the second stage (differential amplifier). The main purpose of the analog delay line is to delay EMG signal and the stimulus artifact between the first and the second stage. It is shown that by introducing a delay line in the standard three op-amp instrumentation amplifier, stimulus artifact can be detected before it appears at the output of the amplifier. Thus the control circuits of the amplifier have enough time to disable the integrator in the differential amplifier, and prevent charge accumulation in the integrators capacitor. It is also shown that this configuration of the EMG amplifier has ultrafast recovery time, so it can be used as a control interface of the neural prosthesis.
Rasch analysis of the WHOQOL-BREF in post polio syndrome.

OBJECTIVE The World Health Organisation quality of life abbreviated scale (WHOQOL-BREF) was developed as a measure of quality of life across 4 separate health domains; physical health, psychological, social relationships and environment. This study evaluated the validity of the WHOQOL-BREF in post-polio syndrome by testing it for fit against the Rasch model. RESULTS The scale was posted to 319 volunteers, 271 (85%) completed the scale with a mean age of 66.7 years (standard deviation 8.15); 64% were female. The social relationships domain fitted the Rasch model (χ2 p = 0.19) but reliability was low (α = 0.69) and there were insufficient items to test the assumption of unidimensionality. Solutions were derived for physical health (p = 0.45, t-test = 1.5%, α = 0.67), psychological (p = 0.19, t-test = 4.9%, α = 0.78) and environment domains (p = 0.48, t-test = 6.0% - lower confidence interval 3.4%, α = 0.80) by accounting for local dependence and to cancel out differential item functioning. An overall measure of quality of life, which combined all 4 domains was validated (p = 0.80, t-test = 4.6%, α = 0.81). A transformation table for this total score is provided. CONCLUSION The 4 domains of the WHOQOL-BREF provide valid measures of quality of life in post-polio syndrome. The summed score was more reliable and better targeted and can be used as an ordinal estimate of quality of life.
Video Defogging Based on Adaptive Tolerance

Dark channel prior is a kind of statistics of the haze-free outdoor images, which is widely used in image defogging. But when the image contains a large bright region, such as sky and white object, the prior will cause color distortion in these bright regions because of the underestimated transmission. To solve this problem, a video defogging technology based on adaptive tolerance is presented in this paper, and it is applied to video defogging by combining with the guided filter. First, the transmission of each video frame is estimated according to the dark channel prior, and then it is fast refined by the guided filter for restoration. If a large bright region exists in the video frame, the transmission of these regions will be corrected according to the adaptive tolerance, which avoids the color distortion in the video defogging. For the video of dynamic scenes which are caused by camera motion, each frame is defogged as a single image. But for the video of static scenes whose background is almost invariant, the transmission of the background is estimated and used for the defogging of all the frames instead of estimating the transmission of each frame. In this way, the rate of video defogging is greatly improved. Experimental results show that the algorithm has a strong applicability, and the proposed method can be further used for many applications, such as outdoor surveillance, remote sensing and intelligent vehicles. DOI: http://dx.doi. org/10.11591/telkomnika.v10i7. 1556 Full Text: PDF
Joint QSAR Analysis Using the Free-Wilson Approach and Quantum Chemical Parameters

Abstract A new quantitative structure-activity relationship (QSAR) technique combining the Free-Wilson method and constructed quantum chemical parameters was used to simulate the aqueous solubility (S w), 1-octanol/water partition coefficient (K ow) of 14 new synthesized benzanilide derivatives and their 96 h acute toxicity (EC50) to Daphnia magna. The mode of action of the 14 selected compounds to Daphnia magna was shown to be a complex process involving a physical partition stage and a biochemical reaction stage. The results also indicated that the joint (QSAR) analysis was much effective than the original Free-Wilson method and Hansch method not only in predicting properties/toxicity, but also in investigating the mode of action of chemicals.
Nested Ensemble Technique for Excellence Real Time Cardiac Health Monitoring

Electrocardiogram (ECG) is a series of waves and deflections recording the cardiac’s (heart) electrical activity sensed by several electrodes. ECG signal utilized to extract very useful information about the functional status of the heart. Of particular interest are the systems designed for monitoring people outdoor and detecting abnormalities (arrhythmia) on the real time. In this paper, we propose a nested ensemble technique for real time arrhythmia classification. Its main components include manipulating the training dataset for learning the classifier by up-to-data training data, and manipulating the ECG features to select the proper adequate set to enhance the accuracy and excellence classification performance. Our experiment works demonstrated the necessity of including all the ECG features in cardiac health evaluation. Moreover prove the outstanding quality achieved by our model.
CAGE unsound for alcohol misuse in seniors

Little is known about the specific features of alcohol misuse among seniors. Morbidity involving alcohol use disorders (AUD) peaks between the 40 and 50 year-old age bracket, and is 2–3-fold higher in males. Elderly people consume less alcohol, and abstinence figures increase with age. The hypothesis of a potentially self-limiting disease has to be counterbalanced by (i) excess mortality in the more severe forms and (ii) late-onset forms often inextricably tied to life events (retirement, social and emotional isolation, disabling physical illness, depressive episodes, etc). In France, in the general population, AUD is present in an estimated 10% of over-65s, and the few studies available cite figures of 11–40% for institutionalized seniors (Brousse et al., 2003). St John et al. recently highlighted in the International Journal of Geriatric Psychiatry (Epub 2008 Oct 6) a particularly important issue in a study entitled ‘‘Alcohol misuse, gender, and depressive symptoms in community-dwelling seniors. ’’ This study classified subjects as Alcohol misusers, Alcohol users and Never users based on drinking status and CAGE questionnaire scores with a cut-off point of 1. However, the results need to be interpreted with extreme caution. The Alcohol misusers group is a poorly characterized population that in all evidence is highly heterogeneous. The cut-off point of 1 maximizes sensitivity but minimizes specificity, and the lifetime version of the CAGE questionnaire unfortunately cannot uncover current misuse. It is difficult to establish a meaningful link between current symptoms of depression and lifetime alcohol misuse. The authors underline that the higher incidence of alcohol misuse among males has to be viewed in the context of the gender-related performance of the CAGE questionnaire. We can offer some clarifications on this point. We took figures from a study led to validate the French version of the CAGE questionnaire (Malet et al., 2005) and extracted the data on over-65s (1488 women and 1149 men). CAGE performance at the conventional cut-off score of 2 was mediocre, with sensitivity gauged at 60% in men and 42% in women. Using 1 as the cut-off score increased sensitivity to 64% in women and 78% in men, but at the same time posting 21% false positives (Table 1). CAGE performance is habitually better in care structurebased populations such as this one. These results therefore raise doubts as to the accuracy of CAGE in the general elderly population. The majority of generic tools for screening alcohol misuse would appear poorly adapted to elderly populations (Reid et al., 2003). The CAGE questionnaire is touted as being among strongest-performing tools in elderly males (Bradley et al., 2001), and is therefore generally employed as the routine option.
Inhibition of both skin and lung tumorigenesis by Car‐R mouse‐derived cancer modifier loci

The Car‐R outbred mouse line was phenotypically selected for high resistance to two‐stage skin tumorigenesis. In the present study we tested the hypothesis that a subset of genetic loci responsible for resistance to skin tumorigenesis of Car‐R mice might also inhibit lung tumorigenesis. Skin and lung tumorigenesis were induced in groups of Car‐R, SWR/J, (SWR/JxCar‐R)F1 and SWR/Jx(SWR/JxCar‐R) backcross mice by i.p. urethane initiation and skin TPA promotion. Car‐R mice showed a much lower susceptibility to both skin and lung tumorigenesis as compared to SWR/J mice, which are susceptible to both lung and skin tumorigenesis. The Car‐R‐inherited genome significantly inhibited both skin and lung cancer development in the F1 progeny of Car‐R with SWR/J mice. In the backcross population, skin and lung tumor phenotypes showed a statistically significant correlation, indicating that a subset of the cancer resistance alleles, which segregated in the Car‐R line during selection for resistance to skin carcinogenesis, provides resistance to both skin and lung tumorigenesis. © 2001 Wiley‐Liss, Inc.
Toward a Model for Assessing Level of Personality Functioning in DSM–5, Part I: A Review of Theory and Methods

Personality disorders are associated with fundamental disturbances of self and interpersonal relations, problems that vary in severity within and across disorders. This review surveyed clinician-rated measures of personality psychopathology that focus on self–other dimensions to explore the feasibility and utility of constructing a scale of severity of impairment in personality functioning for DSM–5. Robust elements of the instruments were considered in creating a continuum of personality functioning based on aspects of identity, self-direction, empathy, and intimacy. Building on preliminary findings (Morey et al., 2011/this issue), the proposed Levels of Personality Functioning will be subjected to extensive empirical testing in the DSM–5 field trials and elsewhere. The resulting version of this severity measure is expected to have clinical utility in identifying personality psychopathology, planning treatment, building the therapeutic alliance, and studying treatment course and outcome.
Chemosensitivity testing of fresh leukaemia cells using the MTT colorimetric assay

We have determined the feasibility of using the MTT colorimetric assay for measuring the sensitivity of fresh leukaemia cells to cytotoxic agents. A linear relationship was seen between the number of leukaemic cells plated and the resulting absorbance in the MTT assay at day 4. For 2 × 105 cells/well from CLL peripheral lymphoctes, the mean absorbance (measured at 540 nm) was 0.41. Similar curves were obtained with the assay carried out between days 3 and 7. ID50 values for CLL lymphocytes exposed to adriamycin (ADM) were in the range of 0.02‐0.29 μg/ml, a similar range to that given by the DiSC dye exclusion assay. Sensitization of leukaemia cells to ADM by verpamil or cyclosporin A could be demonstrated in some patients but not in others. The lymphocytes from one patient with prolymphocytic leukaemia were abnormally resistant to ionizing radiation. These cells also showed resistance to melphalan and adriamycin but not to vincristine. The MTT assay appears to offer an attractive option for in vitro chemosensitivity testing in leukaemia, determination of cross‐resistance profiles and studies of resistance modifiers.
Induction of cytokines in mice with parainfluenza pneumonia

The possible involvement of cytokines in the acute viral pneumonia induced by the murine parainfluenza type 1 virus, Sendai virus, was studied. Cytokine profiles for both the respiratory tract and the draining mediastinal lymph node (MLN) of virus-infected C57BL/6J mice were quantified by using the single-cell cytokine (ELISPOT) assay with freshly isolated cell populations and enzyme-linked immunosorbent assay for lung lavage fluids and culture supernatants. Maximal levels of interleukin 2 (IL-2), gamma interferon (IFN-gamma), tumor necrosis factor, IL-6, and IL-10 were detected at the inflammatory site 7 to 10 days after infection, about the time that virus is cleared from the lung. The frequencies of cells producing IL-2, IL-4, IL-6, IL-10, IFN-gamma, and tumor necrosis factor were much higher for the bronchoalveolar lavage (BAL) cell population than for the MLN cell population. Cytokine production after in vitro restimulation of MLN cells was dominated by IL-2 and IFN-gamma, with low levels of IL-10 and IL-6 also being present. Most of the cytokine was produced by the CD4+ cells, although the CD8+ subset was also involved. No IL-4 was found in the BAL fluid or in culture supernatants from restimulated BAL or MLN cells, although a high frequency of IL-4-producing cells was demonstrated in the BAL population by ELISPOT analysis.
High-Frequency Scalable Electrical Model and Analysis of a Through Silicon Via (TSV)

We propose a high-frequency scalable electrical model of a through silicon via (TSV). The proposed model includes not only the TSV, but also the bump and the redistribution layer (RDL), which are additional components when using TSVs for 3-D integrated circuit (IC) design. The proposed model is developed with analytic RLGC equations derived from the physical configuration. Each analytic equation is proposed as a function of design parameters of the TSV, bump, and RDL, and is therefore, scalable. The scalability of the proposed model is verified by simulation from the 3-D field solver with parameter variations, such as TSV diameter, pitch between TSVs, and TSV height. The proposed model is experimentally validated through measurements up to 20 GHz with fabricated test vehicles of a TSV channel, which includes TSVs, bumps, and RDLs. Based on the proposed scalable model, we analyze the electrical behaviors of a TSV channel with design parameter variations in the frequency domain. According to the frequency-domain analysis, the capacitive effect of a TSV is dominant under 2 GHz. On the other hand, as frequency increases over 2 GHz, the inductive effect from the RDLs becomes significant. The frequency dependent loss of a TSV channel, which is capacitive and resistive, is also analyzed in the time domain by eye-diagram measurements. Due to the frequency dependent loss, the voltage and timing margins decrease as the data rate increases.
Senone log-likelihood ratios based articulatory features in pronunciation erroneous tendency detecting

It is important to provide detailed and instructive feedback in computer assisted pronunciation training (CAPT) system. However the feedback is limited to the accuracy of the erroneous tendency detection. This paper proposed to apply senone log-likelihood ratio based articulatory features (AFs) to improve pronunciation erroneous tendency (PET) detection performance. Also the feedback information of articulation-placement and articulation-manner could be derived from the definition of PET. The framework of the method involved two main steps: (a) A bank of attribute extractors based on neural networks were trained to estimate the log-likelihood ratio (LLR) for each senone at a frame level; (b) AFs composed of those LLRs outputted from each attribute extractor were then used for detecting PETs. Results demonstrated that the system using AFs had better performance than the baseline system using MFCC. Moreover, substantial improvements were obtained by combining AFs with MFCC, achieving a lower false rejection rate of 5.0%, a lower false acceptance rate of 30.8% and a higher diagnostic accuracy of 89.8%.
Thermally Induced Stresses in Glazing Systems

A thorough examination has been performed of the thermally induced stresses on a window in an enclosure-fire environment. Analytical and numerical methods establish the importance of bridling stress (due to axial elongation) and flexing stress (due to normal deformation). Most previous studies omitted the consideration of flexing stresses. Maximum stresses, being the sum of bridling and flexing stresses on the side, have been calculated for varying aspect ratios of a rectangular window and for varying ratios of shaded width to the window sides. For uniform width and heating (e.g., represented, by constant high temperature in the heated region and ambient temperature in the shaded region), the maximum stresses are bridling and equal to those of an infinite strip shaded on two sides when the shaded width is less than 40% of the short side. For nonuniform shading (e.g., due to radiation blockage) or nonuniform heating, flexing stresses contribute to the total stress by an increase up to 50%. These new results have been applied in predicting the magnitude of stresses and the location of the first crack in well-controlled experiments and measurements. These results are important because they extend and delineate the limitations of currently used relations for determining thermally induced stresses and times of first cracking in windows.
Effects of mGST A4 transfection on 4-hydroxynonenal-mediated apoptosis and differentiation of K562 human erythroleukemia cells.

Cellular levels of downstream products of membrane lipid oxidation appear to regulate differentiation in K562 human erythroleukemia cells. 4-Hydroxynonenal (4-HNE) is a diffusible and relatively stable product of peroxidation of arachidonic and linoleic acids, cellular levels of which are regulated through metabolism to glutathione (GSH) conjugate by glutathione S-transferases (GSTs). A group of immunologically related alpha-class mammalian GSTs expressed in mice (mGST A4-4), rat (rGST A4-4), human (hGST A5.8), and other species, as well as the more distantly related human hGST A4-4, preferentially utilize 4-HNE as a substrate and are suggested to be major determinants of intracellular levels of 4-HNE. Present studies were designed to examine the effects of 4-HNE on K562 cells and to study the effect of transfection of mGSTA4-4 in these cells. Exposure of K562 cells to 20 microM 4-HNE for 2 h resulted in a rapid erythroid differentiation of K562 cells, as well as apoptosis evidenced by characteristic DNA laddering. Stable transfection of cells with mGST A4-4 resulted in a fivefold increase in GST-specific activity toward 4-HNE compared with wild-type or vector-only transfected cells. The mGST A4-4-transfected cells were resistant to the cytotoxic, apoptotic, and differentiating effects of 4-HNE. The mGST A4 transfection also conferred resistance to direct oxidative stress (IC(50) of H(2)O(2) 22, 23, and 35 microM for wild-type, vector-transfected, and mGST A4-transfected cells, respectively). mGST A4-4-transfected cells also showed a higher rate of proliferation compared with wild-type or vector-transfected K562 cells (doubling time 22.1 +/- 0.7, 31 +/- 1.2, and 29 +/- 0.6 h, respectively). Cellular 4-HNE levels determined by mass spectrometry were lower in mGST A4-4-transfected cells compared to cells transfected with vector alone (5.9 pmol/5 x 10(7) cells and 62.9 pmol/5 x 10(7) cells, respectively). Our studies show that 4-HNE can induce erythroid differentiation in K562 cells and that overexpression of mGST A4 suppresses 4-HNE levels and inhibits erythroid differentiation and apoptosis.