Miracle-dz/UniFAR-FTUs huggingface dataset:
Meta-DM: An ontology for the data mining domain

Ontologies have been used in various research areas from computer science, including data mining. This article describes the development of a domain ontology for data mining. Meta-DM ontology provides a common terminology that can be shared and processed by data mining tools. The ontology also indicates the KDD phases where human knowledge is necessary this is its greatest differential. With ontologies as the Meta-DM, it is possible to add semantics in the data mining process in order to improve the interaction and cooperation between experts and mining systems.
Fluid loading for cesarean delivery under spinal anesthesia: have we studied all the options?

maternal demographics, surgical times, and fetal outcomes were similar between the 2 groups. CO was significantly higher compared with baseline at 5 minutes in the HS [0.78L/min; 95% confidence interval (CI), 0.26-1.31L/min] and at 5 minutes (1.21L/min; 95% CI, 0.69-1.74L/min) and 10 minutes (0.66L/min; 95% CI, 0.013-1.18L/min) in the HES group with no significant differences between groups. The overall mean difference in CO between the crystalloid and colloid groups over the study period was 0.06 L/min (95% CI, 0.46 to 0.58L/min). The other CO variables were similar between groups. Stroke volume was significantly higher than baseline in both groups during the study (mean difference 11.6mL; 95% CI, 7.4-15.9mL) with no between-group differences. The groups did not differ significantly in peak velocity or FTc, although peak velocity increased significantly at 5, 10, and 15 minutes compared with baseline in the HES group but not in the HS group. FTc increased significantly above baseline in both groups, with the effect sustained in the HES group over 20 minutes but only for 10 minutes in the HS group. The groups did not differ in surgical times, block height at 20 minutes after spinal injection, and maximal cephalad sensory level of anesthesia. No patient required oxygen and no abnormal cardiotocography recordings were obtained. SBP was maintained in both groups, and no hypotensive or hypertensive episodes occurred in either group. No significant differences were found in total phenylephrine dose or in the number of patients needing rescue bolus doses. The fetuses did not differ significantly in umbilical cord gases or Apgar scores (no infant in either group had a score <7 at 1 or 5min). Because no differences in CO variables, vasopressor requirements, or hemodynamic stability were found between colloid and crystalloid coloads in this study, no advantage in using one over the other can be determined when used in combination with a phenylephrine infusion during spinal anesthesia for elective cesarean delivery.
Protein kinase inhibitors reduce SR Ca transport in permeabilized cardiac myocytes.

Phosphorylation of the sarcoplasmic reticulum (SR) protein phospholamban by adenosine 3',5'-cyclic monophosphate (cAMP)-dependent protein kinase (PKA) and Ca-calmodulin-dependent protein kinase (CaM-KII) stimulates Ca-adenosinetriphosphatase (ATPase) activity and SR Ca transport, but the role of CaM-KII-dependent phosphorylation is not well defined. We studied the PKA- and CaM-KII-dependent regulation of SR Ca transport in digitonin-permeabilized rabbit ventricular myocytes. SR Ca uptake and free Ca concentration were measured on line with indo 1 and Ca electrodes in the presence of 20 microM ruthenium red and 10 mM oxalate. neither N5,2'-w-dibutyryl-cAMP (up to 500 microM) nor the nonhydrolyzable cAMP agonist adenosine 3'5'-cyclic monophosphorothioate sodium salt (Sp-cAMP[S]; up to 275 microM) affected the maximum uptake rate (Vmax) or the dissociation constant (Kd) for Ca uptake. However, the PKA inhibitor H-89 significantly increased Kd (e.g., from 307 +/- 67 to 826 +/- 62 nM Ca at 40-65 microM H-89) without significantly affecting Vmax. Both CaM-KII inhibitors, KN-62 (60 microM) and a CaM-KII inhibitory peptide (10 microM), significantly decreased Vmax from 11.95 +/- 0.5 to 9.48 +/- 0.6 nmol.mg-1.min-1 and from 10.95 +/- 1.72 to 7.37 +/- 0.94 nmol.mg-1.min-1, respectively, without consistently changing Kd. The effects of H-89 on Kd and of KN-62 on Vmax were prevented by a monoclonal antibody to phospholamban 2D12 (consistent with the antibody removing the inhibitory effect of phospholamban on the SR Ca-ATPase). (ABSTRACT TRUNCATED AT 250 WORDS)
An Irreversible Single-Use Humidity-Threshold Monitoring Sensor Principle for Wireless Passive Sensor Solutions

Monitoring environmental parameters, which have negative effects on goods (e.g., temperature and relative humidity) to determine threshold or dosage violations, is of strong interest throughout their life cycle. The task is challenging if there is no continuous supply of electric energy available, and lowest cost monitoring solutions are required. These are two common application constraints when passive sensor-enhanced RFID tags are used to fulfill this monitoring task. A sensor principle is proposed in which the exceedance of a humidity threshold followed by critical exposure leads to a permanent change in an electric sensor parameter, i.e., a pronounced electric resistance decrease in the presented case. The sensor principle is based on the phenomena deliquescence of salts for humidity threshold detection and sensor activation mechanism and salt solution dissemination processes in porous media as well as chemical liquid phase sintering of metal nanoparticles under ambient temperature conditions as an irreversible state change mechanism. The sensor principle deduced arrangement is fully compatible with printed electronics manufacturing technologies as exemplified by a sample fabrication via inkjet printing. The proposed sensors can serve as humidity-triggered switches in electric circuits, which permanently close due to critical humidity exposure above a humidity threshold. Presented are experimental results demonstrating the feasibility of the proposed sensor concept. Also given are application examples not only demonstrating the suitability of the sensor concept for sensor enhanced RFID tags via an integration into a freely programmable RFID UHF transponder tag but also for wireless passive sensors exemplified via integration into an inductively coupled resonant sensor tag.
Searching for Optical Counterparts to High-Energy Neutrino Sources with the Zwicky Transient Facility

The IceCube neutrino observatory has discovered a flux of extragalactic neutrinos. However, the origin of these neutrinos is still unknown. Among the possible candidates are Gamma-Ray Bursts (GRBs), Core-Collapse Supernovae (SNe), Active Galactic Nuclei (AGN) and Tidal Disruption Events (TDEs) - all are accompanied by a characteristic optical counterpart. The goal of this study is thus to identify the neutrino sources by detecting their optical counterparts with the Zwicky Transient Facility (ZTF). ZTF features a high cadence northern-sky survey enabling realtime correlation of optical transients with high-energy neutrino candidates. In this talk I will highlight the multimessenger potential of ZTF for an online neutrino correlation study with Ice- Cube.
The suppression of endogenous protein degradation by fractions of foetal calf serum: Dialysed serum is less able to suppress degradation in aged cells

We have studied the effect of various fractions of foetal bovine serum upon the endogenous degradation of long labelled proteins in cultured MRC5 cells, and upon other cellular functions. Only heat‐inactivated serum was capable of suppressing protein degradation to a similar extent to complete serum. Acid‐treated and delipidized sera were moderately effective. Albumin on its own was able to replace 40 per cent of the effect of serum, indicating the exogenous protein might compete with endogenous protein for degradation in lysosomes. Albumin was not capable of supporting DNA synthesis. Dialysed serum showed an age‐related effect suppressing protein degradation to a lesser extent and being less effective in supporting DNA synthesis or cellular proliferation in aged cells. All the effects noted were related to lysosomal protein degradation. Serum diffusate did not suppress protein degradation.
Analysis of Variance Applied to Human Genetics.

Analysis of Variance is a well-known convenient mathematical device by which the total of all squared deviations from the grand mean of some heterogeneous population may be divided into 2 variances, namely, variability about the mean of each of the more homogeneous elements in that population and the variability of these partial means about the grand mean of the entire population. It can be used to answer the question, how does the variability within the homogeneous or elementary group compare with the variability of the groups between one another? For example, how does the variability of the fruits of any one tree of a species compare with the variability of the average fruits of different trees of that species? So far as I know the technique of Analysis of Variance has not yet been applied to human traits measured in a number of fraternities in a population. An opportunity came to me to make this application in the variance of some 14 head measurements made on the boys of 6 families, containing each-from 5 to 3 boys. These dimensions were taken at age 16 years exactly or, in a few cases, by interpolation or extrapolation of a year. The details of handling these sets of variables are well known and need not be considered here. The results are given in the accompanying table. The F values are the quotient of the larger mean square by the smaller mean square. The size of the quotient determines the chances that the F -values are due merely to sampling and accordingly fail to indicate a significant difference between the two sorts of variances-within fraternities and between fraternities. The table reveals that the mean squared variance within a family is, in all 13 traits, less than the variance between families, and that the ratio of one to the other is always significant and usually highly significant. To go into some detail one may point out that the mean square variance in respect to face width between 16-year-old boys of one fraternity is onetwelfth that between different families even when all these families are of t fl3S
Revenue Maximizing Auction when Bidders have Private Budgets

We tackle the problem of designing revenue maximizing auctions in the Bayesian framework, when bidders not only have private valuations but also private budgets. We consider the setting of selling divisible goods to multiple agents each with linear utilities, but agents cannot pay beyond their budget. We focus on the case when the auctioneer can check that bidders do not over-report their budgets, but bidders may under-report. We use a relaxed linear program to bound the optimal auction, and use it to construct a “greedy-queuing” auction that guarantees 1 1/e of the optimal revenue. In fact, the integrality gap of the program is exactly e/(e 1) so the analysis is tight.
A Detector-Based Approach for the  $H_{2} $ Control of Markov Jump Linear Systems With Partial Information

In this paper, we study the H2-control for discrete-time Markov Jump Linear Systems (MJLS) with partial information. We consider the case in which we do not have access to the Markov jump parameter but, instead, there is a detector that emits signals which provides information on this parameter. A salient feature of our formulation is that it encompasses, for instance, the cases with perfect information, no information and cluster observations of the Markov parameter, which were previously analyzed in the Markov jump control literature. The goal is to derive a feedback linear control using the information provided by the detector in order to stochastically stabilize the closed loop system. We present two Lyapunov like equations for the stochastic stability of the system. In addition, we show that a Linear Matrix Inequalities (LMI) formulation can be obtained in order to design a stochastically stabilizing feedback control. In the sequel we deal with the H2 control problem and we show that, again, an LMI optimization problem can be formulated in order to design a stochastically stabilizing feedback control with guaranteed H2-cost. We also present two special cases, one of them always satisfied for the limit case in which the detector provides perfect information on the Markov parameter, and the Bernoulli jump case, under which LMI conditions become necessary and sufficient for the stochastic stabilizability of the system and the LMI optimization problems provide the optimal H2 cost. For the Bernoulli jump case we show that our formulation generalizes previous ones. The case with convex polytopic uncertainty on the parameters of the system and on the transition probability matrix is also considered. The paper is concluded with some numerical examples.
Adaptations in Physiology and Propulsion Techniques During the Initial Phase of Learning Manual Wheelchair Propulsion

de Groot S, Veeger HEJ, Hollander AP, van der Woude LHV: Adaptations in physiology and propulsion techniques during the initial phase of learning manual wheelchair propulsion. Am J Phys Med Rehabil 2003;82:504–510. ObjectiveThe purpose of this study was to analyze adaptations in gross mechanical efficiency and wheelchair propulsion technique in novice able-bodied subjects during the initial phase of learning hand-rim wheelchair propulsion. DesignNine able-bodied subjects performed three 4-min practice blocks on a wheelchair ergometer. The external power output and velocity of all blocks was, respectively, 0.25 W/kg and 1.11 m/sec. Gross mechanical efficiency, force application, timing, and intercycle variability were measured. ResultsNo change in gross mechanical efficiency was found. However, a decrease in push frequency occurred, which was accompanied by an increase in work per cycle and a decrease in percentage push time. The increase in work per cycle was associated with a higher peak torque. No changes in intercycle variability were visible over time. ConclusionsThe timing variables had already changed during the initial phase of learning manual wheelchair propulsion. However, for other variables, such as force production, gross mechanical efficiency, and intercycle variability, a longer practice period might be necessary to induce a change. The effective force direction seemed to be optimized from the start of the learning process onward.
A multichannel portable ECG system with capacitive sensors

Capacitive sensors can be employed for measuring the electrocardiogram of a human heart without electric contact with the skin. This configuration avoids contact problems experienced by conventional electrocardiography. In our studies, we integrated these capacitive electrocardiogram electrodes in a 15-sensor array and combined this array with a tablet personal computer. By placing the system on the patient's body, we can measure a 15-channel electrocardiogram even through clothes and without any preparation. The goal of this development is to provide a new diagnostic tool that offers the user a reproducible, easy access to a fast and spatially resolved diagnostic ‘heart view’.
Growth factors protect in vitro cultured embryos from the consequences of oxidative stress

The aim of the study was to evaluate the effect of insulin-like growth factors (IGF1 and IGF2), stem cell factor (SCF) and epidermal growth factor (EGF) on the development of embryos exposed to oxidative stress. C3B6F1 female mice were stimulated with 5 IU of pregnant mare serum gonadotropin and 5 IU of equine chorionic gonadotropin (eCG). Two-cell embryos were flushed out from the fallopian tubes 40 h after eCG administration and mating with DBA males. In each experiment embryos were divided into three groups and cultured in (1) control medium, (2) control medium with 0.1 mM hydrogen peroxide and (3) control medium with hydrogen peroxide and separately with IGF1, IGF2, SCF or EGF in concentrations of 1 ng/ml, 10 ng/ml and 100 ng/ml. Under phase-contrast microscopy, 8-cell and compacted embryos, and early, expanded, hatched and outgrown blastocysts were counted at 24 h. The total blastocyst (TB) and inner cell mass (ICM) cell numbers were established by differential staining. Blastocyst cell viability was examined under fluorescence microscopy. To detect apoptosis, TUNEL was performed and visualized under a laser scanning confocal microscope. Hydrogen peroxide decreased embryo growth, blastocyst rates, blastocyst cell viability as well as TB and ICM counts. The TUNEL reaction revealed significantly more apoptotic cells in oxidative stress conditions. Tested factors revealed a varying extent of protective activity against oxidative stress caused by hydrogen peroxide. In media containing hydrogen peroxide and one of the four tested factors (IGF1, IGF2, SCF or EGF) the embryos developed faster than in media with hydrogen peroxide alone. IGF1, IGF2 and EGF increased both TB and (or) ICM counts in embryos exposed to hydrogen peroxide. All tested factors reduced the number of apoptotic cells (TUNEL) in embryos exposed to hydrogen peroxide.
Can Older People With Schizophrenia Benefit From Work Rehabilitation?

To determine whether older people with schizophrenia or schizoaffective disorder can benefit from work therapy as has been shown with their younger counterparts, 41 older patients (50+) were compared with 104 younger patients on their clinical and vocational outcomes while participating in a 6-month work therapy program. In an intent-to-treat analysis, both groups showed significant improvements in symptoms and quality of life at the conclusion of the active intervention, but there were no significant differences between age groups. In comparisons of biweekly Work Behavior Inventory scores for completers, older workers improved more than younger workers, particularly during the second half of the program. Results are in accord with previous evidence for the clinical and vocational benefits of work therapy and indicate that older people with schizophrenia or schizoaffective disorder can perform at least as well as their younger counterparts and respond similarly with improved symptoms and quality of life.
Glutathione S‐transferase GSTM1, GSTM3, GSTP1 and GSTT1 genotypes and the risk of smoking‐related oral and pharyngeal cancers

Several polymorphic glutathione S‐transferase enzymes are involved in the detoxification of active metabolites of many potential carcinogens from tobacco smoke and may therefore be important in modulating susceptibility to smoking‐related cancers. As part of a hospital‐based case‐control study performed in France among Caucasian smokers, we studied GSTM1, GSTM3, GSTP1 and GSTT1 gene polymorphisms in 121 patients with oral cavity and pharyngeal cancers and 172 hospital controls using peripheral blood DNA. An increase in risk was found among carriers of the GSTP1 (AG or GG) genotype (OR 1.6, 95% CI 1.0–2.8, p = 0.07) or the GSTT1 null genotype (OR 2.0, 95% CI 1.0–4.0, p = 0.05). The effect of these at‐risk genotypes was most marked in subjects with a history of more than 30 years of smoking, among whom the respective ORs were 2.0 (95% CI 1.0–3.9) and 3.3 (95% CI 1.3–8.1), though the interaction tests between these genotypes and duration of smoking were not significant. In contrast, neither the GSTM1 null genotype nor the GSTM3 AA genotype was associated with oropharyngeal cancer risk (OR 0.9, 95% CI 0.5–1.5 and OR = 1.3, 95% CI 0.7–2.3, respectively). Our results thus suggest that GSTP1 and GSTT1 gene polymorphisms modulate susceptibility to smoking‐related cancers of the oral cavity and pharynx. Int. J. Cancer 81:44–48, 1999. © 1999 Wiley‐Liss, Inc.
Multi-Bound-Dependent Stability Criterion for Digital Filters With Overflow Arithmetics and Time Delay

In this brief, a new criterion for checking the global asymptotic stability of fixed-point state-space digital filters with time-varying delay and overflow arithmetics is presented. Compared with some existing results, a distinctive feature of the proposed criterion is that it is multi-bound-dependent criterion and can be less conservative than existing results. Two examples are given to show this improvement over the existing conditions.
Attachment and temperament revisited: infant distress, attachment disorganisation and the serotonin transporter polymorphism

Abstract Objective: This study’s aim was to evaluate whether infant disorganised attachment and infant proneness to distress exhibited differential relations to infant genetic factors as indexed by the serotonin transporter polymorphism. Background: The role of the short allele of the serotonin transporter polymorphism (5-HTTLPR) in enhancing sensitivity to fearful and negative affect has been well-established. In the current study, we used this known property of the short allele to provide a test of an important postulate of attachment theory, namely that infant attachment security or disorganisation is not a function of the infant’s proneness to distress. Methods: Participants were 39 parents and infants assessed between 12 and 18 months in the Strange Situation Procedure. Genotype categories for the 5-HTTLPR (and rs25531) were created by both the original and the reclassified grouping system; infant proneness to distress was assessed directly in the Strange Situation Procedure. We also assessed maternal behaviour at 18 months to evaluate whether any observed genetic effect indicated a passive effect through the mother. Results: Consistent with previous findings, the 5-HTTLPR short allele was significantly related to the infant’s wariness and distress, but was not related to attachment security or attachment disorganisation. In addition, maternal disrupted interaction with the infant was not related to infant genotype or infant distress. Conclusion: Results support the concept that infant proneness to distress is associated with serotonergic factors while infant attachment security or disorganisation is not a function of either 5-HTTLPR or behaviourally rated proneness to distress.
Performance analysis of an OCR system via an artificial handwritten Chinese character generator

A handwritten Chinese character generator that generates handwritten Chinese characters with different variations is proposed and used for evaluating the performance of an OCR system. The character generator first generates radicals of a character stroke by stroke and then combines the generated radicals to form a line-vector character. Then, the line-vector character is thickened to obtain a character image. The generated characters are then used to evaluate the stability of stroke extractors and calculate the peak performance of a matching module and the recognition error caused by stroke extractors. <<ETX>>
Regularizer Performance for SparseCT Image Reconstruction With Practical Subsampling

Low-dose X-ray computed tomography (CT) is a major area of research due to the diagnostic capability of CT counterbalanced by the risk of radiation exposure. The standard method for reducing the dose is to decrease the tube current, but this negatively impacts image quality at high dose reduction factors due to photon starvation effects. We investigate an alternative paradigm, called SparseCT, in which a multi-slit collimator (MSC) is placed between the source and the patient. Interrupting the X-ray beam in this way reduces radiation dose to the patient and produces undersampled data from which the image can be estimated using sparse image reconstruction techniques. However, the MSC introduces a number of new considerations, including penumbra effects that require wider slits and more spacing between slits in order to optimize dose efficiency and beam separation. These design choices reduce incoherence in the undersampling scheme and affect the performance of standard edge-preserving/sparsity-promoting regularizers. Here, we simulate these effects in the ideal setting where penumbra effects do not increase the noise in the sinogram. For modest 4-fold retrospective undersampling factors, we observe a slight degradation in an abdominal scan between incoherent-optimal and practical MSC designs for SparseCT. In the future, we plan to use the simulation to inform MSC design prior to fabrication.