Miracle-dz/UniFAR-FTUs huggingface dataset:
A new class of exact solutions of the Navier-Stokes equations for swirling flows in porous and rotating pipes

Flow field analysis through porous boundaries is of great importance, both in engineering and bio-physical fields, such as transpiration cooling, soil mechanics, food preservation, blood flow and artificial dialysis. A new family of exact solution of the Navier–Stokes equations for unsteady laminar flow inside rotating systems of porous walls is presented in this study. The analytical solution of the Navier–Stokes equations is based on the use of the Bessel functions of the first kind. To resolve these equations analytically, it is assumed that the effect of the body force by mass transfer phenomena is the ‘porosity’ of the porous boundary in which the fluid moves. In the present study the effect of porous boundaries on unsteady viscous flow is examined for two different cases. The first one examines the flow between two rotated porous cylinders and the second one discusses the swirl flow in a rotated porous pipe. The results obtained reveal the predominant features of the unsteady flows examined. The developed solutions are of general application and can be applied to any swirling flow in porous axisymmetric rotating geometries.
Healthy Work: Ideal and Reality among Public and Private Employed Academics in Sweden

In what does healthy work for persons with an academic background consist, and how great is the perceived gulf between actual work and healthy work? A random sample of 5,700 members of the Swedish Confederation of Professional Associations (SACO) was taken in order to investigate their images of healthy work (in a very broad sense). Two groupings of work aspects emerged as particularly important. The first can be designated as work intellectuality—that work provides intellectual stimulation and is performed freely and independently, that innovative thinking and initiative-taking are appreciated, and that personal qualities can be utilized constructively. Great discrepancies between ideal and reality were evident in the latter two aspects. The second significant set of aspects was the value of work—benefit of the work to society and the extent to which it accorded with personal values. Here, the correspondence between ideal and actual work was relatively high. Lowest ranked of the twelve aspects which were judged to constitute healthy work were being well paid and having opportunities for career advancement. Rank orders and discrepancies are analyzed for seven occupational groups: physicians, dentists, teachers, engineers, university teachers, lawyers and economists. Comparisons are made by gender, age, employer, and position.
Knowledge-aided STAP algorithm using convex combination of inverse covariance matrices for heterogenous clutter

Knowledge-aided space-time adaptive processing (KA-STAP) algorithms, which incorporate a priori knowledge into radar signal processing methods, have the potential to substantially enhance detection performance while combating heterogeneous clutter effects. In this paper, we develop a KA-STAP algorithm to estimate the inverse interference covariance matrix rather than the covariance matrix itself, by combining the inverse of the covariance known a priori, R0-1, and the inverse sample covariance matrix estimate R̂-1. The computational load is greatly reduced due to the avoidance of the matrix inversion operation. We also develop a cost-effective algorithm based on the minimum variance (MV) criterion for computing the mixing parameter that performs a convex combination of R0-1 and R̂-1. Simulations show the potential of our proposed algorithm, which obtain substantial performance improvements over prior art.
Postvaccination Increase in Serotype 19A Pneumococcal Disease in Norway Is Driven by Expansion of Penicillin-Susceptible Strains of the ST199 Complex

ABSTRACT Serotype replacement in invasive pneumococcal disease has been observed after widespread use of the 7-valent pneumococcal conjugate vaccine (PCV7). Replacement is dominated by penicillin-nonsusceptible serotype 19A in several countries. Antibiotic selection pressure has been proposed to interact with immunization, leading to rapid replacement. In Norway, where prescription of antibiotics is limited, post-PCV7 replacement by serotype 19A is dominated by penicillin-susceptible clones. Hence, serotype 19A replacement occurs, although it is not driven by antibiotic selection pressure.
An Extended Contract-Net Negotiation Model Based on Task Coalition and Genetic Algorithm

Multi-agent negotiation has been one of the key problems in the multi-agent research area. An extended contract-net negotiation model based on task coalition and genetic algorithm is presented after analyzing the advantage and disadvantage of the classical contract-net negotiation model. Formalized definition method and coalition generation algorithm are given. A specialized genetic algorithm, which is optimized by optimized initial colony selection, optimized parent crossover/mutation and the using of Metropolis rule, is used to solve the task allocation in the coalition. The algorithm improves the efficiency of task allocation and reduces the communication cost. By testing and analyzing an example of a missile defense system, it is proved that the model can reduce the negotiation cost effectively contrast with the classical contract-net model on the basis of ensuring the negotiation quality.
Pattern Recognition for Industrial Monitoring and Security using the Fuzzy Sugeno Integral and Modular Neural Networks

We describe in this paper the evolution of modular neural networks using hierarchical genetic algorithms for pattern recognition. Modular neural networks (MNN) have shown significant learning improvement over single neural networks (NN). For this reason, the use of MNN for pattern recognition is well justified. However, network topology design of MNN is at least an order of magnitude more difficult than for classical NNs. We describe in this paper the use of a hierarchical genetic algorithm (HGA) for optimizing the topology of each of the neural network modules of the MNN. The HGA is clearly needed due to the fact that topology optimization requires that we are able to manage both the layer and node information for each of the MNN modules. Simulation results prove the feasibility and advantages of the proposed approach.
Detection of random targets in sensor networks with applications

Abstract This paper considers the detection of random targets modelled by a hidden Markov chain using distributed multiple sensors. The optimization problem is formulated as an optimal stopping problem which intends to increase the capturing probability of the moving object. The general formulation in this paper may be applied for distributed (change or failure) detection in a networked system, which generalizes the traditional quickest detection.
Experiences of cognitive coaching

Objectives: Cognitive coaching and cognitive behavioural coaching are approaches practiced by many coaching psychologists (Palmer & Whybrow, 2007). However, there is a lack of qualitative studies evaluating these approaches. The main objective of/with the present study was to investigate a number of participants’ experiences of cognitive coaching.
Semiurgy: From Language Analysis to Language Synthesis

The article focuses on the transition from language analysis to language synthesis as a new strategy in the performative humanities of the early 21st century. In addition to semiotics, the practical discipline of semiurgy (signformation) is described in the context of growing creative potential of electronic communications. For philosophy, it means the turn to linguistic vitalism as an attempt to synthesize the legacies of Nietzsche and Wittgenstein.
Seasonal dynamics of bacterial and archaeal methanogenic communities in flooded rice fields and effect of drainage

We studied the resident (16S rDNA) and the active (16S rRNA) members of soil archaeal and bacterial communities during rice plant development by sampling three growth stages (vegetative, reproductive and maturity) under field conditions. Additionally, the microbial community was investigated in two non-flooded fields (unplanted, cultivated with upland maize) in order to monitor the reaction of the microbial communities to non-flooded, dry conditions. The abundance of Bacteria and Archaea was monitored by quantitative PCR showing an increase in 16S rDNA during reproductive stage and stable 16S rRNA copies throughout the growth season. Community profiling by T-RFLP indicated a relatively stable composition during rice plant growth whereas pyrosequencing revealed minor changes in relative abundance of a few bacterial groups. Comparison of the two non-flooded fields with flooded rice fields showed that the community composition of the Bacteria was slightly different, while that of the Archaea was almost the same. Only the relative abundance of Methanosarcinaceae and Soil Crenarchaeotic Group increased in non-flooded vs. flooded soil. The abundance of bacterial and archaeal 16S rDNA copies was highest in flooded rice fields, followed by non-flooded maize and unplanted fields. However, the abundance of ribosomal RNA (active microbes) was similar indicating maintenance of a high level of ribosomal RNA under the non-flooded conditions, which were unfavorable for anaerobic bacteria and methanogenic archaea. This maintenance possibly serves as preparedness for activity when conditions improve. In summary, the analyses showed that the bacterial and archaeal communities inhabiting Philippine rice field soil were relatively stable over the season but reacted upon change in field management.
Manipulating DNA damage-response signaling for the treatment of immune-mediated diseases

Significance Therapeutic immune suppression is essential for treating a variety of immune conditions, including autoimmune diseases, immunoregulatory disorders, and in transplantation. Reliance on broadly acting drugs carries substantial risks, and even pathway-specific agents are problematic, because most immune pathways have essential functions. The ideal form of immune suppression would be antigen-specific, suppressing an undesired immune response but sparing all others. We describe a unique strategy for therapeutic immune suppression, relying on targeted manipulation of DNA damage-response signaling, that exploits unique aspects of lymphocyte biology. This approach allows for highly selective suppression of recently activated T cells, displays clear therapeutic benefits, and has less off-target toxicity than conventional DNA-damaging drugs. Antigen-activated lymphocytes undergo extraordinarily rapid cell division in the course of immune responses. We hypothesized that this unique aspect of lymphocyte biology leads to unusual genomic stress in recently antigen-activated lymphocytes and that targeted manipulation of DNA damage-response (DDR) signaling pathways would allow for selective therapeutic targeting of pathological T cells in disease contexts. Consistent with these hypotheses, we found that activated mouse and human T cells display a pronounced DDR in vitro and in vivo. Upon screening a variety of small-molecule compounds, we found that potentiation of p53 (via inhibition of MDM2) or impairment of cell cycle checkpoints (via inhibition of CHK1/2 or WEE1) led to the selective elimination of activated, pathological T cells in vivo. The combination of these strategies [which we termed “p53 potentiation with checkpoint abrogation” (PPCA)] displayed therapeutic benefits in preclinical disease models of hemophagocytic lymphohistiocytosis and multiple sclerosis, which are driven by foreign antigens or self-antigens, respectively. PPCA therapy targeted pathological T cells but did not compromise naive, regulatory, or quiescent memory T-cell pools, and had a modest nonimmune toxicity profile. Thus, PPCA is a therapeutic modality for selective, antigen-specific immune modulation with significant translational potential for diverse immune-mediated diseases.
Diseases of Aquatic Organisms Dis Aquat Org Experimental Susceptibility of Turbot Scophthalmus Maximus to Viral Haemorrhagic Septicaemia Virus Isolated from Cultivated Turbot

Juvenile pathogen-free turbot were infected with a viral haemorrhagic septicaemia virus (VHSV) isolate recovered from turbot cultivated on the island of Gigha, West Scotland. Mortality of 100% was recorded in fish lnfected via the intra-peritonea1 (i.p.) route. Horizontal transmission of VHSV in sea water was demonstrated by cohabitation of naive fish with i.p. infected fish at a ratio of 1:l. The total cumulative average mortality in cohabiting fish was 60% by 60 d post-infection. Turbot infected via an immersion route exhibited a cumulative average mortality of 71 % by the end of the experiment. VHSV identified by enzyme-linked immunosorbent assay (ELISA) was recovered from both organ (kidney and spleen) and brain samples of individual fish that died following infection by all experimental routes. These findings pose significant implications regarding the persistence of VHSV and its role in limiting natural populations of marine fish species. In addition, the establishment of infection models for the transmission of VHSV in sea water is of fundamental importance to the development of anti-VHSV vaccines in important commercial species such as turbot.
Changes Related to Age in Natural and Acquired Systemic Self-IgG Responses in Malaria

Background. Absence of acquired protective immunity in endemic areas children leads to higher susceptibility to severe malaria. To investigate the involvement of regulatory process related to self-reactivity, we evaluated potent changes in auto-antibody reactivity profiles in children and older subjects living in malaria-endemic zones comparatively to none-exposed healthy controls. Methods. Analysis of IgG self-reactive footprints was performed using Western blotting against healthy brain antigens. Plasmas of 102 malaria exposed individuals (MEIs) from endemic zone, with or without cerebral malaria (CM) were compared to plasmas from non-endemic controls (NECs). Using linear discriminant and principal component analysis, immune footprints were compared by counting the number, the presence or absence of reactive bands. We identified the most discriminant bands with respect to age and clinical status. Results. A higher number of bands were recognized by IgG auto-antibodies in MEI than in NEC. Characteristic changes in systemic self-IgG-reactive repertoire were found with antigenic bands that discriminate Plasmodium falciparum infections with or without CM according to age. 8 antigenic bands distributed in MEI compared with NEC were identified while 6 other antigenic bands were distributed within MEI according to the age and clinical status. Such distortion might be due to evolutionary processes leading to pathogenic/protective events.
Informational and emotional elements in online support groups: a Bayesian approach to large-scale content analysis

OBJECTIVE This research examines the extent to which informational and emotional elements are employed in online support forums for 14 purposively sampled chronic medical conditions and the factors that influence whether posts are of a more informational or emotional nature. METHODS Large-scale qualitative data were obtained from Dailystrength.org. Based on a hand-coded training dataset, all posts were classified into informational or emotional using a Bayesian classification algorithm to generalize the findings. Posts that could not be classified with a probability of at least 75% were excluded. RESULTS The overall tendency toward emotional posts differs by condition: mental health (depression, schizophrenia) and Alzheimer's disease consist of more emotional posts, while informational posts relate more to nonterminal physical conditions (irritable bowel syndrome, diabetes, asthma). There is no gender difference across conditions, although prostate cancer forums are oriented toward informational support, whereas breast cancer forums rather feature emotional support. Across diseases, the best predictors for emotional content are lower age and a higher number of overall posts by the support group member. DISCUSSION The results are in line with previous empirical research and unify empirical findings from single/2-condition research. Limitations include the analytical restriction to predefined categories (informational, emotional) through the chosen machine-learning approach. CONCLUSION Our findings provide an empirical foundation for building theory on informational versus emotional support across conditions, give insights for practitioners to better understand the role of online support groups for different patients, and show the usefulness of machine-learning approaches to analyze large-scale qualitative health data from online settings.
Analyses of the cag pathogenicity island of Helicobacter pylori

Most strains of Helicobacter pylori from patients with peptic ulcer disease or intestinal‐type gastric cancer carry cagA, a gene that encodes an immunodominant protein of unknown function, whereas many of the strains from asymptomatically infected persons lack this gene. Recent studies showed that the cagA gene lies near the right end of a ≈37 kb DNA segment (a pathogenicity island, or PAI) that is unique to cagA+ strains and that the cag PAI was split in half by a transposable element insertion in the reference strain NCTC11638. In complementary experiments reported here, we also found the same cag PAI, and sequenced a 39 kb cosmid clone containing the left ‘cagII’ half of this PAI. Encoded in cagII were four proteins each with homology to four components of multiprotein complexes of Bordetella pertussis (‘Ptl’), Agrobacterium tumefaciens (‘Vir’), and conjugative plasmids (‘Tra’) that help deliver pertussis toxin and T (tumour inducing) and plasmid DNA, respectively, to target eukaryotic or prokaryotic cells, and also homologues of eukaryotic proteins that are involved in cytoskeletal structure. To the left of cagII in this cosmid were genes for homologues of HslU (heat‐shock protein) and Era (essential GTPase); to the right of cagII were homologues of genes for a type I restriction endonuclease and ion transport functions. Deletion of the cag PAI had no effect on synthesis of the vacuolating cytotoxin, but this deletion and several cag insertion mutations blocked induction of synthesis of proinflammatory cytokine IL‐8 in gastric epithelial cells. Comparisons among H. pylori strains indicated that cag PAI gene content and arrangement are rather well conserved. We also identified two genome rearrangements with end‐points in the cag PAI. One, in reference strain NCTC11638, involved IS605, a recently described transposable element (as also found by others). Another rearrangement, in 3 of 10 strains tested (including type strain NCTC11637), separated the normally adjacent cagA and picA genes and did not involve IS605. Our results are discussed in terms of how cag‐encoded proteins might help trigger the damaging inflammatory responses in the gastric epithelium and possible contributions of DNA rearrangements to genome evolution.
Bandstop filters of suspended stripline design using the quasi-lumped element approach

In this paper, bandstop filters of suspended stripline are proposed. The filters are a ladder circuit structure which has the shunt-circuit modules in the series branches and the series-circuit ones in the ladder's shunt arms. Each of these individual modules provides a transmission zero whose frequency can be independently tuned. Two bandstop filters are built from utilizing three and five of these zero-generating circuit modules, respectively. The rejection bandwidth is dominated by the distribution of the zeros. The quasi-lumped elements circuit model is developed to analyze the circuit performance and the experiments are conducted to verify the filters' design.
Notice of RetractionResearch on the Performance of Flood Routing in High-Speed Mobile Ad Hoc Networks

High transfer rate between the nodes is the key to the high-speed mobile ad hoc networks, the factors as the node's transmit power control, the overall energy consumption, the network lifetime can be ignored. So firstly, analyzing the forward and backward packet receiving rate, then establish the required number of expected sending packets model ETX. Finally, comparing the flood routing and multi-hop routing models and the difference was simulated. By comparing the result, it was validated that flood routing has an excellent performance.
Factoring elementary groups of prime cube order into subsets

Let p be a prime and let G be the 3-fold direct product of the cyclic group of order p. Redei conjectured if G is the direct product of subsets A and B, each of which contains the identity element of G, then either A or B does not generate all of G. The paper verifies Redei's conjecture for p ≤ 11.
Angular Power Spectra of the COBE DIRBE Maps

The angular power spectra of the infrared maps obtained by the Diffuse Infrared Background Experiment (DIRBE) instrument on the COBE satellite have been obtained by two methods: (1) the Hauser-Peebles method previously applied to the Differential Microwave Radiometer experiment maps, and (2) by Fourier transforming portions of the all-sky maps projected onto a plane. The two methods give consistent results, and the power spectrum of the high-latitude dust emission is Cℓ ∝ ℓ-3 in the range 2 < ℓ < 300.
The Effect of Diagnosis, Age, and Symptom Severity on Cortical Surface Area in the Cingulate Cortex and Insula in Autism Spectrum Disorders

Functional activity in the anterior cingulate cortex and insula has been reported to be abnormal during social tasks in autism spectrum disorders. However, few studies have examined surface morphometry in these regions and how this may be related to autism spectrum disorder symptomatology. In this study, 27 individuals with autism spectrum disorders and 25 controls between the ages of 7 to 39 years underwent structural magnetic resonance imaging. Our primary analysis examined differences in surface area in the cingulate and insula, between individuals with and without autism spectrum disorders, as well as age-related changes and associations with social impairments. Surface area in the right cingulate was significantly different between groups and decreased more rapidly with age in autism spectrum disorder participants. In addition, greater surface area in the insula and isthmus was associated with poorer social behaviors. Results suggest atypical surface morphometry in brain regions involved in social function, which appeared to be related to poorer social ability scores.
An Auditory Display in Playlist Generation

A current area of research within music information retrieval is the automatic formation of music playlists: automatically creating a meaningful arrangement of music tracks. It is an application area particularly suited for accessing music on mobile devices as music collections are becoming too large to manually navigate. The growth of music streaming services means that even more vast collections of music are accessible from a mobile device. Much energy has been spent constructing the best algorithms to create a playlist, but less has been spent on how that algorithm is presented and accessed, particularly on a mobile device.