Miracle-dz/UniFAR-FTUs huggingface dataset:
Inhibitory neural activity predicts response to cognitive-behavioral therapy for posttraumatic stress disorder.

OBJECTIVE Despite cognitive-behavioral therapy (CBT) being an effective treatment for posttraumatic stress disorder (PTSD), many patients do not respond to CBT. Understanding the neural bases of treatment response may inform treatment refinement, thereby improving treatment response rates. Adequate working memory function is proposed to enable engagement in CBT. METHOD This study employed a Go/No-Go task to examine inhibitory function and its functional brain correlates as predictors of response to CBT in PTSD. Participants were recruited between October 2003 and May 2005. Thirteen treatment-seeking patients who met DSM-IV criteria for PTSD completed the Go/No-Go task while undergoing functional magnetic resonance imaging (fMRI), after which they entered 8 once-weekly sessions of CBT. PTSD severity was measured before treatment and again at 6 months following treatment completion using the Clinician-Administered PTSD Scale (primary outcome measure). RESULTS After controlling for initial PTSD severity and ongoing depressive symptoms, greater activity in left dorsal striatal (Z = 3.19, P = .001) and frontal (Z = 3.03, P = .001) networks during inhibitory control was associated with lower PTSD symptom severity after treatment, suggesting better treatment response. CONCLUSIONS These results suggest that neural circuitry underpinning inhibitory control plays a role in the outcome of CBT for patients with PTSD. TRIAL REGISTRATION anzctr.org Identifier: ACTRN12610000017022.
Epidemiology of Helicobacter pylori infection among the healthy population in Iran and countries of the Eastern Mediterranean Region: a systematic review of prevalence and risk factors.

AIM To investigate the epidemiology of Helicobacter pylori (H. pylori) infection among the healthy asymptomatic population in Iran and countries of the Eastern Mediterranean Region. METHODS A computerized English language literature search of PubMed, ISI Web of Science, Scopus, and Google Scholar was performed in September 2013. The terms, "Eastern Mediterranean Regional Office (EMRO)" and "Helicobacter pylori", "H. pylori" and "prevalence" were used as key words in titles and/or abstracts. A complementary literature search was also performed in the following countries: Afghanistan, Bahrain, Djibouti, Egypt, Iran, Iraq, Jordan, Kuwait, Lebanon, Libya, Morocco, Oman, Pakistan, Palestine, Qatar, Saudi Arabia, Somalia, Sudan, Syria, Tunisia, The United Arab Emirates, and Yemen. RESULTS In the electronic search, a total of 308 articles were initially identified. Of these articles, 26 relevant articles were identified and included in the study. There were 10 studies from Iran, 5 studies from the Kingdom of Saudi Arabia, 4 studies from Egypt, 2 from the United Arab Emirates, and one study from Libya, Oman, Tunisia, and Lebanon, respectively. The overall prevalence of H. pylori infection in Iran, irrespective of time and age group, ranged from 30.6% to 82%. The overall prevalence of H. pylori infection, irrespective of time and age group, in other EMRO countries ranged from 22% to 87.6%. CONCLUSION The prevalence of H. pylori in EMRO countries is still high in the healthy asymptomatic population. Strategies to improve sanitary facilities, educational status, and socioeconomic status should be implemented to minimize H. pylori infection.
Opportunistic fog computing: Feasibility assessment and architectural proposal

Cloud computing has been pointed out as one of the pillars of the Internet of Things, providing this emerging infrastructure with unlimited resources and easing its deployment. However, cloud computing relies on remote, mainly centralized resource provisioning, which poses substantial problems in the support of time-critical and location-aware IoT applications. Fog computing, on the other hand, recently emerged as an intermediate solution to solve the mentioned cloud computing limitations, but its embryonic status still prevents it from being used in real developments.
Effect of Test Environment on Intervertebral Disc Hydration

Study Design Water content of fresh human lumbar intervertebral discs (with adjacent endplates) was assessed in three studies: 1) after each of seven specimen preparation steps, 2) during exposure to either saline spray or a saline bath, and 3) during exposure to a saline bath and 445 N axial compression, either without or with previous exposure to the bath and no compression (“free swelling”). Objective To assess the effect on disc hydration of various aspects of specimen preparation and testing environments. Summary of Background Data Water content is an important determinant of disc behavior. Specimen preparation method and testing environments may be important determinants of water content, yet no work appears to have been reported specifically on this topic. Methods Endplate-disc-endplate specimens were prepared from refrigerated cadavers within 24 hours of death by transverse sectioning of adjacent vertebral bodies. Water content change was determined by specimen weight change across each time interval of interest. Results Specimen preparation (including multiple freeze-thaw cycles) produced no water content change. Saline spray and plastic film wrap resulted in no change, but saline bath exposure resulted in a 24% increase over 7 hours, 44% of which occurred in the first 0.5 hour. A subsequent 7 hours of 445 N compression reduced the overall increase to 10%. This was not significantly different from the 8% increase that resulted from initial exposure to saline bath and compression. Conclusions Specimen preparation as typically performed and specimen exposure to saline spray and plastic film wrap do not result in hydration change. Exposure to saline bath results in substantial swelling, which can either be reversed or prevented by axial compression in the physiologic range. Whether discs exposed to saline spray and wrap without compression and those exposed to saline bath with compression behave the same and which of these more closely mimics the in vivo condition are important issues for the experimentalist to test.
IN NURSING PRACTICE From hospital to home care : a randomized controlled trial of a Pain Education Programme for cancer patients with chronic pain

742 Ó 2001 Blackwell Science Ltd Correspondence: Rianne de Wit, University Hospital Rotterdam, Pain Expertise Center-Dijkzigt Hospital, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands. E-mail: dewit@pijn.azr. nl D E W IT R. & V A N D A M F. ( 2 00 1 ) Journal of Advanced Nursing 36(6), 742±754 From hospital to home care: a randomized controlled trial of a Pain Education Programme for cancer patients with chronic pain Aim of the study. To investigate the role of district nurses in the care of cancer patients with chronic pain at home, as well as the effects of a Pain Education Programme for patients and their district nurses. The Pain Education Programme consisted of a tailored multi-method approach in which they were educated about pain, instructed how to report pain, and how to contact health care providers. Background. No educational programs for patients in pain have been studied in outpatients nor integrated with the home care provided. Design and methods. One hundred and four patients and their 115 district nurses were enrolled in a prospective, longitudinal, randomized controlled study. The primary outcome of interest was type of care provided by district nurses, satisfaction with the pain treatment, and agreement in estimating patients' pain intensity. Results. Results showed that continuity of care was poor as only 36% of the district nurses were informed about patients' pain by hospital nurses. Pain was rarely the reason for referring the patient to district nursing after discharge. Although pain control was not a main reason for district nurses to visit a patient, pain was a subject for discussion in 76% of visits. Besides discussing the pain problem with patients, district nurses provided only a few pain-relieving interventions. District nurses randomized to the intervention group signi®cantly better estimated patients' pain intensity, and were more satis®ed about patients' pain treatment, but no differences were found in their assessment of patients' pain relief. Conclusions. These ®ndings suggest a signi®cant but moderate effect of the Pain Education Programme, with district nurses only playing a minor role in the treatment of cancer pain.
Developmental Expression of Cytochrome P450S within Intrasplenically Transplanted Fetal Hepatocytes from Spontaneously Hypertensive Rats

Fetal hepatocytes were harvested at 20 days of gestation from spontaneously hypertensive rats (SHR) and then transplanted into recipient adult SHR spleens. Morphological examination of the recipient spleens revealed that after 4 wk, large masses of hepatocytes were present in the red pulp with apparent cord-like structures. Of major significance was the fact that hepatocyte transplanted spleens were able to express several families of cytochrome P450 (cyto P450) proteins 2-6 wk after transplantation. Thus, the transplanted hepatocyte tissue appeared to grow and develop a cyto P450 metabolic system. Immunochemical determinations revealed that cytos P450 IA1, P450 IIB1, P450 p, P450 HLp, and P450 LAω were over detected without any prior induction. None of the cyto P450s could be detected in control nontransplanted spleens, however all were detected in fetal hepatocyte microsomes before transplantation. All were intensely expressed 6 wk after transplantation, however P450 IA1 and P450 IIB1 did not appear to be expressed by 2 wk after transplantation. These results demonstrate that fetal hepatocytes can be successfully transplanted to the spleens of recipient hosts, and that the fetal hepatocytes appear to grow and develop functional cyto P450 metabolizing systems. Therefore, transplantation of fetal hepatocytes to splenic tissue represents a unique in vivo system of extra hepatic metabolizing tissue.
An Empirical Analysis on Hostile vs. Friendly Acquisition and Effects on Employment

This paper provides empirical evidence on the impact of friendly and hostile acquisitions on the firm employment and labour workforce in the United Kingdom using a specific collected database for the period of 1988-2011 and UK quoted companies. The understanding of this paper is to provide results in terms of recognizing whether hostile acquisitions are harmful to employment and decrease the demand for labour. The results exhibits otherwise, as it does not find any evidence to support the theory that hostile companies are more detrimental to the employment in comparison to friendly acquisitions. However, the paper does find descriptive statistics to what changes during and after the merger events, more specifically, in the labour productivity, real output, employment and wage rate variables. The aforementioned variables do suffer in both types of mergers and acquisitions except for wage rate. Conclusively, hostile and friendly acquisitions do not display any significant relationship with the changes in labour demand and employment, thereby, going against the popular belief that hostile takeovers reduce employment and job loss.
The Effect of Risperidone on Cognition in Patients with Schizophrenia

Objective: To evaluate the effect of risperidone on cognitive functions after both 6 weeks and 6 months of treatment and to determine whether any improvement on neuropsychological function relates to improvement in psychopathology. Method: Patients' psychiatric and extrapyramidal symptoms were assessed while they were receiving classical neuroleptic treatment and adjunctive medications. Patients were then reassessed after changing to a new treatment of risperidone. Results: During treatment with risperidone, schizophrenic patients displayed improved performance mainly on attentional components, specifically, selective attention and alertness. Conclusion: In patients who were given risperidone, there was a positive correlation between improvement in psychopathology and improvement in cognitive tests of explicit memory and alertness.
Study of Rats' Mammary Precancer models-induced by DMBA combined estrogen and progesterone

Objective: To explore using 7, 12-Dimethylbenz[a] anthracen(DMBA) combined estrogen and progesterone induce Rats Model of Mammary Precancer, and investigate the inhibitory effect of tamoxifen ointment. Methods: 30 virginal female SD rats were randomly allocated into three groups, A: Blank control group (10); B: DMBA+hormones group (10); C: TAM group (10). The general morphology and pathology were observed when the rats were executed after 60 days. Results: The incidence of premalignant breast disease in model group B was 87.5%, while group C was 47.5%. Group B was significantly higher than group C (P<0.01). Conclusion: DMBA+hormones method is a method to establish Rats Model of Mammary Precancer. Tamoxifen could effectively prevent the occurrence of DMBA+hormon-es induced breast precancer in rats.
Projective Camera Model in Biomedical Navigation Applications

Computer assisted navigation is a widely adopted technique in neurosurgery and orthopedics. However, it is rarely used for surgeries on abdominal organs. In this paper, we propose a novel, noninvasive method based on electromagnetic tracking to determine the pose of the kidney. As a clinical use case, we show a complete surgical navigation system for augmented reality assisted laparoscopic partial nephrectomy. Experiments were performed ex vivo on pig kidneys and the evaluation showed an excellent augmented reality alignment error of 2.1 mm ± 1.2 mm.
Therapeutic Letters as Relationally Responsive Practice

Therapeutic letters have become a practice adopted by many clinicians as an adjunct to therapeutic conversations. This article presents selected findings from a larger study that examined both the letter-writing practices of nine clinicians as well as the experiences of seven adult clients who received a therapeutic letter or letters during the course of individual or family therapy. A novel aspect of this study is that data from clients were gathered in the form of letters—eight letters written by the clients to the researcher about their experience of receiving a therapeutic letter or letters from their clinician. Thematic analysis guided the analysis of the data. Findings are placed within the context of relationally responsive (or relationally engaged) practice. An invitation is extended to conceptualize letters not as monologic documents but as a means of dialogically relating to clients and to the “goings-on” of therapeutic conversations.
Pattern extraction from northern Thai fabrics using flexibly matching segments: Sarong Teenjok and Lanna textiles

This paper proposes a method with flexibility in detecting and recognizing northern Thai fabrics which usually include various delicate patterns or traceries. Due to delicacies in unique patterns of northern Thai fabrics, especially ones called Sarong Teenjok or even other Lanna textiles, flexibility in searching and detecting such patterns is required. Authors thus propose a method using some parameters allowed to be adjusted in order to add flexibility in pattern recognition. Thus, some small deviation, orientation, or different shadows and shades of the appeared traceries does not cause much problem. From experimental results, the proposed method still works very well in various challenging situations as mentioned, for example, in cases of having shadows in the input image, natural skewness or unnatural orientation of the fabrics, or some small deviation in pattern's colors of the traceries.
Audit quality, family business and corporate governance mechanisms: the case of Morocco

Purpose The purpose of this paper is to investigate the effect of various corporate governance mechanisms such as board structure, ownership structure and debt level on the demand for better external audit quality. Design/methodology/approach Using a sample of 142 non-financial Moroccan companies, the authors examine the impact of the above corporate governance mechanisms on the audit quality of firms. The empirical model is tested with firms which include family businesses as well as listed and non-listed Moroccan companies. Findings The authors find a positive association between the demand for audit quality and the proportion of independent directors. The authors find evidence that the debt level has no impact on the demand for a better external audit; however, that there exists a complementary effect between the control exercised by independent directors and the demand for external audit quality. For ownership structure, the authors find a significant negative relation between the presence of blockholders and institutional investors and the demand for differentiated external audit quality, confirming the substitution hypothesis. Originality/value The paper has practical importance for corporate governance mechanism and audit quality in the developing economies of Africa. The study highlights that most family businesses have efficient corporate governance mechanism and therefore do not need to rely on the big audit firms for quality audit.
Leadership and organizational performance: a study of large corporations.

Leadership influence in large complex organizations, though commonly assumed to be greatly significant, is normally not studied in terms of the variance accounted for in organizational performance. The leadership effect is viewed here as a product of an organization's environmental constraints and its leadership variance. Based on sales, earnings, and profit margin data for 167 large corporations over twenty years, we compare the impact of leadership changes with yearly, industry, and company influences. Industry and company account for far more of the variance in two performance variables than does leadership, but not for profit margins after lag effects are considered. It appears that the importance of external restrictions, and hence the maximum possible leadership influence, may range widely between specific performance criteria. The second phase of the study considers industry characteristics that appear to be associated with high and low leadership influences. These results suggest a perspective on organization performance that may be applied to the leadership influence in other large organizations and political bodies, like cities, states and nations.
The Influence Of Brand Equity Dimensions Towards Purchase Intention Of Samsung Smartphone On College Student At The Faculty Of Economics And Business University Of Brawijaya Malang

The aim of this study is to examine the influence of Brand Equity (Brand Awareness, Brand Association, Perceived Quality and Brand Loyalty) on Purchase Intention of Samsung Smartphone on College Student in Faculty Economics and Business University of Brawijaya Malang. The research is explanatory research which explains the causal relation between the variables through hypothesis testing. The data collection technique of this study uses questionnaires. This study used 120 samples are the student who ever used Samsung Smartphone. The sampling technique used purposive sampling and the research instruments were tested using the Validity Test, Reliability Test, The hypothesis used Partial (t-Test) using Partial Linear Square (PLS) analysis technique to analyze the data. The result from this study showed that variable of brand awareness, brand association, perceived quality, and brand loyalty provides good value and each of them made a significant effect to purchase intention. Keywords:Brand Awareness, Brand Association, Perceived Quality, Brand Loyalty and Purchase Intention.
Cost of construction: how globalization impacts on vernacular houses

Historically people in vernacular area did not have to pay to become a householder or a landowner, or even to buy materials. But that is not the case in modern era any more. Besides the fact that one has to buy land or house, modern materials and technology, spread out by the flow of globalization, has also been associated with increasing cost. In this study on vernacular houses in Northern Iran, traditional (Kali, Lar deh ee, and Mud Houses) and modern (load bearing brick wall structure, concrete structure and steel structure) construction technologies have been investigated with regards to their cost. Residents, experts and contractors were interviewed to collect the data. Findings showed that the perception of cost is a skewed one, and decision to choose a new material or technical over san old one needs to be rational.
Promises from trametinib in RAF active tumors.

Progression of human cancer occurs through genetic changes in cancer cells that activate biochemical pathways governing hallmarks of cancer, including proliferation and tumor-cell survival,1 among others. Tumor growth factor receptors activate RAS oncoproteins, which subsequently activate a kinase cascade that includes RAF, MEK, and ERK kinases. This pathway is mutated to promote tumor growth in at least 20% of cancers.2 The RAS–MEK–ERK pathway is thus a focus of intense interest for the development of cancer drugs. First fruits from this quest have yielded drugs directed against growth factor receptors, including the monoclonal antibody trastuzumab and the small molecules erlotinib and .
An Ultra Sparse Matrix Converter with a Novel Active Clamp Circuit

The ultra sparse matrix converter (USMC) is a AC-DC-AC converter that requires only 9 power switches compared to the 18 switches required for a conventional matrix converter. The simplified input switch configuration restricts this converter to unidirectional power flow applications in which the maximum displacement angle between input and output voltages and currents is plusmnpi/6. A novel clamp circuit is therefore used to protect the converter from overvoltages incurred under regeneration conditions. This paper presents the design of a 5.5 kVA USMC which uses space vector modulation in combination with a zero current commutation scheme at the input rectifier stage. The design of the system is detailed and the hardware implementation of the converter is described. Experimental results demonstrate the operation of the clamp circuit and show that the converter draws sinusoidal currents from the input and supplies sinusoidal currents to the output with a conversion efficiency of up to 94%.
Fingerprint classification using the stochastic approach of ridge direction information

Large scale, automatic fingerprint identification systems (AFISs) perform fingerprint classification to improve matching accuracy and reduce the matching time before fingerprint matching. Fingerprints are classified into several classes such as arch (A), whorl (W), left loop (L) and right loop (L). The existing systems generally classify fingerprints based on the information of singular points. This approach is well suited for fingerprints acquired using paper and ink. However, it is not as efficient with recent automatic fingerprint systems because it cannot guarantee that singular points are well extracted since the recent systems have various sized sensors and use multifarious fingerprint acquisition methods. In this paper, a novel approach is proposed to use the fingerprint ridge direction, which is one of the global features. It is a probabilistic approach based on the fingerprint ridge characteristics of each class. FVC2000 DB1 and FVC2002 DB1 databases were used to evaluate the performance of our classification. Furthermore, the effectiveness of applying the probabilistic model to the classification of various exceptional fingerprint patterns was verified.