Miracle-dz/UniFAR-FTUs huggingface dataset:
Update on acute endovascular and surgical stroke treatment

Emergency stroke care has become a natural part of the emerging discipline of neurocritical care and demands close cooperation between the neurologist and neurointerventionists, neurosurgeons, and anesthesiologists. Endovascular treatment (EVT), including intra‐arterial thrombolysis, mechanical thrombectomy and angioplasty/stenting, is under rapid development. Although EVT has yet to be shown in randomized controlled trials to improve clinical outcome compared to intravenous thrombolysis, it is far better in achieving recanalization of occluded large cerebral vessels, which is crucial for rescuing the penumbra. Moreover, decompressive craniectomy is now a well‐established treatment option for malignant middle cerebral artery infarction and cerebellar stroke. Using a case‐based approach, this article reviews recent achievements in advanced treatment options for patients with acute ischemic stroke.
Simulation of Large Crowds Including Gaseous Phenomena

Crowd animation and simulation have been widely studied over the last decade for many purposes : populating collaborative virtual environments, entertainment and special effects industry and finally simulating behaviors and motion of people in emergency situations for safety systems. This last topic is addressed in this paper. We propose an original enhancement of a well known physics-based animation model which allows to consider influence of gaseous phenomena such as smoke or toxic gases in the behavior of the crowd. In order to get real time performances we also propose an implementation of this framework on modern graphics hardware, which allows to simulate crowds of thousands individuals at interactive framerate.
The Contours of Omission in South Sudan ’ s Higher Education System

DOI: 10.21276/sjhss.2017. 2.11. 12 Abstract: In this paper, I argue that there is clear evidence of neglect of higher education in post-independent South Sudan. The study, therefore, interrogates the scope of the higher education crisis in the country and assesses prospects for change from the standpoint of equity and quality using institutionalism as a theoretical framework. The study points out that the crisis of the system runs through the tapestry of South Sudan’s history of state formation against which the variable of nation-building at the dawn of Independence in 2011 has failed to assign adequate value for higher education in the pursuit of the objectives of national transformation in particular, and modernisation in general. It remains to be seen if the political leadership and the academic community could define the payload of South Sudan’s higher education system as the country transitions into a constitutional democracy capable of according greater autonomy and initiative to its universities; and revisiting the whole gamut of post-secondary education in order to render it more responsive to addressing the needs of society, particularly in non-academic streams of learning. Besides the historical and institutional challenges, the higher education system of South Sudan must expedite its internationalisation as its formative years wane out. The fundamental requirement is for its competent and dynamic scholars to lead a spirited dialogue and concerted action that should not be broken off by recurrent political violence. This is a must if South Sudan is to stand on the cusp of real transformation in its higher education landscape.
Fully embedded myoelectric control for a wearable robotic hand orthosis

To prevent learned non-use of the affected hand in chronic stroke survivors, rehabilitative training should be continued after discharge from the hospital. Robotic hand orthoses are a promising approach for home rehabilitation. When combined with intuitive control based on electromyography, the therapy outcome can be improved. However, such systems often require extensive cabling, experience in electrode placement and connection to external computers. This paper presents the framework for a stand-alone, fully wearable and real-time myoelectric intention detection system based on the Myo armband. The hard and software for real-time gesture classification were developed and combined with a routine to train and customize the classifier, leading to a unique ease of use. The system including training of the classifier can be set up within less than one minute. Results demonstrated that: (1) the proposed algorithm can classify five gestures with an accuracy of 98%, (2) the final system can online classify three gestures with an accuracy of 94.3% and, in a preliminary test, (3) classify three gestures from data acquired from mildly to severely impaired stroke survivors with an accuracy of over 78.8%. These results highlight the potential of the presented system for electromyography-based intention detection for stroke survivors and, with the integration of the system into a robotic hand orthosis, the potential for a wearable platform for all day robot-assisted home rehabilitation.
Locating Cardiac Ischemia

The paper describes an optimization problem of identifying heart ischemia using ECG measurements on the torso surface. Heart ischemia is a condition of reduced blood supply to cardiac tissue and can lead to heart infarctions. In the simulations, we model the cardiac electrical activity by a stationary form of the bidomain equations. These are solved using an adaptive finite element method on a realistic geometrical model of the heart, lungs and torso, obtained from magnetic resonance imaging data. To model the ischemic region, we use a set of parameters in a level set framework. The ischemia is identified by minimizing a cost functional. Since this is a severly ill-posed problem, we investigate the effect of different regularization methods.
Income inequality and well-being in the U . S . : evidence of geographic-scale-andmeasure-dependence

U.S. income inequality has risen dramatically in recent decades. Researchers consistently find that greater income inequality measured at the state or national level is associated with diminished subjective well-being (SWB) in the U.S. We conduct the first multi-scale analysis (i.e., at the ZIP-code, MSA, and state levels) of the inequality-SWB relationship using SWB data from the U.S. Gallup Healthways Well-Being Index and income inequality data from the American Community Survey. We use the rich set of SWB measures afforded by the dataset (evaluative, positive hedonic, and negative hedonic) to examine the consistency of the relationship. We find that the relationship is both scale-dependent and measure-dependent: income inequality is SWB-diminishing in large regions for all measures, SWB-diminishing in small regions for negative hedonic measures, and SWBimproving in small regions for evaluative and positive hedonic measures. Lastly, we find that taking all regions together, the net relationship between income inequality and SWB is negative for all hedonic measures.
Arginine methylation mediated by the Arabidopsis homolog of PRMT5 is essential for proper pre-mRNA splicing

Protein arginine methylation, one of the most abundant and important posttranslational modifications, is involved in a multitude of biological processes in eukaryotes, such as transcriptional regulation and RNA processing. Symmetric arginine dimethylation is required for snRNP biogenesis and is assumed to be essential for pre-mRNA splicing; however, except for in vitro evidence, whether it affects splicing in vivo remains elusive. Mutation in an Arabidopsis symmetric arginine dimethyltransferase, AtPRMT5, causes pleiotropic developmental defects, including late flowering, but the underlying molecular mechanism is largely unknown. Here we show that AtPRMT5 methylates a wide spectrum of substrates, including some RNA binding or processing factors and U snRNP AtSmD1, D3, and AtLSm4 proteins, which are involved in RNA metabolism. RNA-seq analyses reveal that AtPRMT5 deficiency causes splicing defects in hundreds of genes involved in multiple biological processes. The splicing defects are identified in transcripts of several RNA processing factors involved in regulating flowering time. In particular, splicing defects at the flowering regulator FLOWERING LOCUS KH DOMAIN (FLK) in atprmt5 mutants reduce its functional transcript and protein levels, resulting in the up-regulation of a flowering repressor FLOWERING LOCUS C (FLC) and consequently late flowering. Taken together, our findings uncover an essential role for arginine methylation in proper pre-mRNA splicing that impacts diverse developmental processes.
Adolescents’ and Young Adults’ Experiences of Childhood Cancer: Descriptions of Daily Life 5 Years After Diagnosis

Background: Survivors of childhood cancer are a growing population in society. These young people have a high risk of developing chronic health problems with a potential strong impact on their lives. How a childhood cancer experience affects survivors in adolescence has been studied to a limited extent; an increased understanding of this young group is needed to improve follow-up care. Objective: The aim of this study was to gain a deeper understanding of how childhood cancer affects the lives of survivors by exploring adolescents’ and young adults’ views of what it is like living with this experience. Methods: Fifty-nine 11- to 22-year-olds were interviewed a median of 5 years after a cancer diagnosis (response rate, 66%). Data were collected through telephone interviews and were analyzed using qualitative content analysis techniques. Results: Three groups of informants were identified according to their descriptions of the influence of cancer treatment on their daily life: “feeling like anyone else” (informants who described that the cancer experience had almost no influence on current life) (49%), “feeling almost like others” (those who described some influence) (44%), and “feeling different” (those describing a great influence on current life) (7%). Conclusions: Most of the adolescents and young adults appear to get along well, although many informants described that life was affected to some extent by having had cancer. Implications for Practice: Follow-up care is needed that can identify those young survivors of childhood cancer having trouble with daily life and offer them support to strengthen their resources in managing difficulties in relation to having had cancer.
SLkit : An R package for property extraction and analysis of multiple Sensing Layers ∗

The popularisation of smartphones and the increased use of mobile applications allow users to become not only consumers but also data producers. Data shared voluntarily by users through mobile applications open unprecedented opportunities to generate useful knowledge, identify and solve issues, and provide new services. Due to the complexity of urban phenomena and the large volume of data available, stages such as modelling, preprocessing and analysis of sensing layers can be time-consuming. To help to tackle that issue, this study presents an R package intended to give support to researchers regarding decision making and evaluation of sensing layers. It provides functions for property extraction and multilayered analysis which can be customised according to one’s project needs, helping to leverage new applications that explore the concept of sensing layers.
User Grouping for Non-orthogonal Multiple Access ( NOMA )

An unprecedented growth is being witnessed in the number of connected devices in the current cellular networks due to the proliferation of smart devices and novel applications. Thus, new paradigms are being investigated to enhance the spectral efficiency and number of connections to support this deluge of traffic produced by these devices and applications. Non-orthogonal multiple access (NOMA) is a novel scheme that is envisioned to overcome the challenges of spectral efficiency and limited number of connections in the existing cellular networks compared to the traditional orthogonal frequency division multiplexing (OFDMA) scheme. In NOMA, multiple users can be scheduled non-orthogonally to enhance the spectral efficiency. However, a significant challenge is to find a set of users that can be scheduled or grouped together over the limited spectrum in efficient way. In this paper, we present a novel scheme based on matching games that can group multiple users on a spectrum resource to form a group such that the network wide utility is maximized. Simulation results reveal the effectiveness of our proposal in terms of spectral efficiency and number of connected devices.
Atlas current connection tests performed on Pegasus II

Atlas is a 23 MJ pulsed-power facility presently in the design and construction phase at Los Alamos. Atlas will be capable of delivering a damped sinusoidal current pulse with a peak current of 27-32 MA at 4 /spl mu/s. In the center of the Atlas machine, the current converges radially to a load through the powerflow channel which is a flat and conical transmission line. The current connections to the power flow channel are at a radius of approximately one-meter, where the maximum linear current density will be of the order of 51 kA/cm. The Pegasus II facility at Los Alamos has been used to provide peak currents of 5 MA in 6 /spl mu/s to test various types of current connections applicable to the connections for the Atlas powerflow channel. A total of 32 current connections, scaled to produce current densities and actions similar to Atlas conditions, were tested. Since the powerflow channel will be replaced after each shot, most of the connections were tested under single shot conditions.
Coenzyme Q 10 Ameliorates Cadmium Induced Reproductive Toxicity in Male Rats

R. SAHA, S. ROYCHOUDHURY, K. KAR, A. C. VARGHESE, P. NANDI, G. D. SHARMA, G. FORMICKI, P. SLAMA, A. KOLESAROVA Department of Life Science and Bioinformatics, Assam University, Silchar, India, Mediland Hospital and Research Centre, Itkhola, Silchar, India, Astra Fertility Group, Mississauga, Ontario, Canada, Department of Environmental Science, University of Calcutta, India, Atal Bihari Vajpayee University, Bilaspur, India, Department of Zoology of Vertebrates, Institution of Biology, Pedagogical University of Cracow, Poland, Department of Animal Morphology, Physiology and Genetics, Mendel University in Brno, Brno, Czech Republic, Department of Animal Physiology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Nitra, Slovak Republic
Learning Pose Grammar for Monocular 3 D Pose Estimation

In this paper, we propose a pose grammar to tackle the problem of 3D human pose estimation from a monocular RGB image. Our model takes estimated 2D pose as the input and learns a generalized 2D-3D mapping function to leverage into 3D pose. The proposed model consists of a base network which efficiently captures pose-aligned features and a hierarchy of Bi-directional RNNs (BRNNs) on the top to explicitly incorporate a set of knowledge regarding human body configuration (i.e., kinematics, symmetry, motor coordination). The proposed model thus enforces high-level constraints over human poses. In learning, we develop a data augmentation algorithm to further improve model robustness against appearance variations and cross-view generalization ability. We validate our method on public 3D human pose benchmarks and propose a new evaluation protocol working on cross-view setting to verify the generalization capability of different methods. We empirically observe that most state-of-the-art methods encounter difficulty under such setting while our method can well handle such challenges.
Safety Considerations for Humanoid Robots

The issue of assuring the safe operation of humanoid robots may well be one of the greatest challenges facing humanoid robot researchers. It is almost a certainty that legal restrictions will prohibit the general deployment of humanoid robots until a high level of safety can be guaranteed. This paper discusses the key issues for safe operation of humanoid robots and identifies the key technical developments which will be necessary to achieve this goal in next-generation robots. It also presents an overview of approaches investigated for industrial robot safety and assesses how relevant these approaches are for humanoid robot safety.
Urine and Kidney Epidermal Growth Factor: Ontogeny and Sex Difference in the Mouse

ABSTRACT: We have explored the physiology of urinary epidermal growth factor (EGF) in the mouse by studying its ontogeny, and the effects of testosterone therapy on immunoreactive EGF (IR-EGF) concentrations in urine, kidney, serum and submandibular gland (SMG). Urine IREGF (U-EGF) increased about 100-fold relative to urea concentration and about 1000-fold relative to urine volume from the 1st day of life to adulthood. Most of this increase occurred between days 6 and 18, which is the known period of steep rise in plasma thyroid hormone concentration in the mouse. A small F > M sex difference was present in the adult. This difference was opposite in direction to the large M > F sex difference in adult SMG-EGF concentration. On day 26 (age of appearance of morphological sex difference in SMG) the sex difference was not yet present in urine, although in SMG it was even larger than in the adult. Kidney EGF concentration was low relative to UEGF: 1 ml of adult urine contained approximately as much IR-EGF as 100 pairs of adult kidneys. In the adult, but not on day 26, there was a sex difference in kidney EGF concentration parallel to the sex difference in urine: female levels were about 30% higher than male levels. Ten days of testosterone treatment of adult female mice evoked an increase in IR-EGF concentration which was 1.7-fold for serum and S-fold for SMG. In contrast, this treatment did not increase kidney or urine IR-EGF concentrations although kidney weight increased 1.3-fold. Our findings suggest that U-EGF originates from sources other than the SMG or blood. Rapid synthesis and secretion by the kidney may occur. Thyroid hormone appears to be a major regulator of U-EGF, but other factors also seem to be involved.
Grant of Feed Containing Vitamin E in Home Fish Kelabau ( Osteochilus Kelabau ) to Improve Quality Eggs and Larvae

Absract: This study was conducted as long as six months from May – October 2013, located at the soil ponds owned by the Hatchery Laboratory and fish breeding, University of Riau. The purpose of this study was to evaluate the best dose of Vit E added to fish pellets on egg quality of kelabau fish (Osteochilus kelabau) which includes: time for gonadal maturity achievement, ovisomatic index, laten time, number of ovulating eggs, maximum egg dimeter at the end of experiment, percentage of fertilized eggs, hatching rate and survival rate of larva. Applied doses of Vit E were 0, 100, 150, 200 mg/kg pellets. The results show that the best dose of VIT E to reach gonad maturity was 200 mg/kg pellets with three months cultivation period. Laten time was 13.5 hours and the average number of ovulated eggs were 4, 807. The ovisomati index was 0.82 % and the average diameter of eggs after treatments was o.14 mm. Fertilization rate was 0.61 %, with hatching rate was 16.68 %. Unfortunately, survival rate of larve was 0 % after 3 days old.
Predicting Recidivism Among Male Batterers 2000 – 06

ii Predicting recidivism among male batterers.1 Criminal lifestyle . 2 Pro-abuse attitudes.3 Deterrence . 3 Motivation to change . 4 Marital distress.5 Low verbal skills.5 Negative family background.5 Method . 6 Subjects . 6 Measures . 7 Predictor variables . 9 Recidivism criteria . 12 Procedure . 14 Results.14 Combinations of risk factors.29 Discussion.30 Conclusions.34 References.35
Gain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia

Acquisition of additional genetic and/or epigenetic abnormalities other than the BCR/ABL fusion gene is believed to cause disease progression in chronic myeloid leukemia (CML) from chronic phase to blast crisis (BC). To gain insights into the underlying mechanisms of progression to BC, we screened DNA samples from CML patients during blast transformation for mutations in a number of transcription factor genes that are critical for myeloid–lymphoid development. In 85 cases of CML blast transformation, we identified two new mutations in the coding region of GATA-2, a negative regulator of hematopoietic stem/progenitor cell differentiation. A L359V substitution within zinc finger domain (ZF) 2 of GATA-2 was found in eight cases with myelomonoblastic features, whereas an in-frame deletion of 6 aa (Δ341–346) spanning the C-terminal border of ZF1 was detected in one patient at myeloid BC with eosinophilia. Further studies indicated that L359V not only increased transactivation activity of GATA-2 but also enhanced its inhibitory effects on the activity of PU.1, a major regulator of myelopoiesis. Consistent with the myelomonoblastic features of CML transformation with the GATA-2 L359V mutant, transduction of the GATA-2 L359V mutant into HL-60 cells or BCR/ABL-harboring murine cells disturbed myelomonocytic differentiation/proliferation in vitro and in vivo, respectively. These data strongly suggest that GATA-2 mutations may play a role in acute myeloid transformation in a subset of CML patients.
Comparison the Phytotoxicity of TiO 2 nanoparticles with bulk particles on Amber 33 variety of rice ( Oryza sativa ) in vitro .

This study focus on the phytotoxicity of TiO2 nanoparticles (NPs) compared with bulk TiO2 particles B on: germination parameters, vegetative traits, roots viability, Biomass of seedling and photosynthetic pigments of Amber 33 variety of Rice (Oryza Sativa) in vitro. There were induction in seed germination percentage using different concentrations of B particles, while it decreased when the seeds exposed to NPs at concentrations (10, 1 and 0.01) mg/ml compared with control. There were differences between the effects of NPs compared with B particles on germination percentage. The highest germination rate had seen at (0.1 and 0.01) mg/ml concentration of NPs. The same features had seen at (1 and 10) mg/ml of B particles. Other concentrations were reduce the germination rate. All concentrations of NPs were reduced mean germination time. The same reduction has seen at (1-10) mg/ml of B particles. The lower concentrations (0.1-0.01) mg/ml of it were increased. The concentrations of B particles (10, 1 and 0.1) mg/ml showed increased in mean daily germination, whereas higher concentrations of NPs (10 and 1) mg/ml decreased it. However slight increase at 0.1 mg/ml and 0.01 mg/ml of it in MDG was observed. All concentrations of B particles were increase: vigor index I, vigor index II, germination value and promoter indicator compared with control. There were different changing in vigor index I in dose of NPs depending manner. There were differences between the effects of NPs (0.01, 1 and 10) mg/ml compared with B particles on vigor index I, vigor index II and promoter indicator. B particles and NPs were not effect on: shoots, roots, hairy roots length and total of plant lengths. While there were induction in number of hairy roots using 0.01 mg/ml concentration of NPs. NPs (10 and 1) mg/ml concentrations were reduced the number of hairy roots compared with control. The effect of these concentrations were different from the effect of the same concentrations of B particles. NPs and B particles were not effect on: biomass of seedling, chlorophyll A, chlorophyll B and root viability except the medium concentration of B particles, (0.01mg/ml), it reduce root viability.