Miracle-dz/UniFAR-FTUs huggingface dataset:
YAŞLILAR İÇİN EGZERSİZ UYGULAMALARININ ÖNEMİ

Yasli nufusu gunumuz dunyasinda hizla artmaktadir. Ozellikle gelismis ulkelerde dogum oranlarinda ki dususe paralel olarak yasli nufusunda artis daha fazladir. Artan yasli nufus, ulkelerin onemli aktif dinamiklerini etkileyecek duruma gelmektedir. Ozellikle 65 yas ve uzeri bireylerde bircok hayati fonksiyonlar da gerileme gorulmektedir. Meydana gelen bu gerileme bireylerin fiziksel ve zihinsel fonksiyonlarini etkilemektedir. Ilerleyen donemlerde olusan bu gerilemeler yaslilari yardima ihtiyaci olan birey haline getirecektir. Arastirmanin Onemi: Bu calismada yaslilarin daha aktif olmalari icin gunluk hayat icerisinde, ozelliklede kendi baslarina yapabilecekleri egzersiz uygulamalarinin onemi vurgulanmaya calisilmistir. Arastirmanin Amaci: Yasli bireylerin kendi baslarina yapabilecekleri egzersizlerin orneklerle gosterilmesi ve uygulanmasinin yasli bireyleri daha aktif hale getirilmesi amac edinilmistir. Arastirmanin Modeli: Arastirma tarama modelinde hazirlanmistir. Arastirmanin Sonucu: Arastirmanin sonucunda yasli bireyler icin kendi baslarina yapabilecekleri egzersiz uygulamalarinin yasli bireylerin fiziksel ve zihinsel fonksiyonlarinda gelismelere sebep olacagi anlasilmaktadir. Yasli bireyler kendi kisisel ihtiyaclarini karsilayacak durumda olduklarinda, ailelerinin ve devletin bakimina ihtiyac duymadan hayatlarini devam ettirebilirler. Dolayisiyla yasli bireylerin gunluk bircok aktivite icerisinde olmalari yasli bireyler icin cok onem arz etmektedir.
Behavioral Intentions in Satisfaction Research Revisited

Intentions are usually included as dependent variables in satisfaction models, but satisfaction researchers have paid little attention to the discussion in psychology and philosophy in which different intention constructs are distinguished. In this paper, we examine - empirically and conceptually - the satisfaction-intention link with respect to three different intention constructs. The main result is that satisfaction is not equally correlated with these three intentions, and it suggests that satisfaction researchers should be concerned with the particular intention constructs they use: the selection of one particular intention indicator over another will generate different conclusions about the role of satisfaction as a determinant of intentions. Since behavioral data are seldom collected by satisfaction researchers (intentions are often used as a proxy for behavior), different conclusions about the satisfaction-intention link are also likely to affect conclusions about customer behavior.
Understanding OSS Peer Review Roles in Peer Review Social Network (PeRSoN)

Due to the distributed collaborations and the volunteering nature of Open Source Software (OSS), OSS peer review processes differs from traditional approaches. Despite the latest research efforts to understand OSS peer review processes, very little is known. Unlike related work, this study investigates OSS peer review processes from a different perspective. We investigate the importance of OSS peer review contributor roles and their review activities by using social network analysis (SNA), proposed as PeRSoN (Peer Review Social Network). As a case study, we extracted and analyzed the review process of Android Open Source Project (AOSP). To the best of our knowledge, this is the first research constructing social networks from mining a peer review repository. Our preliminary results provided hints on relationships among the OSS peer review contributor roles, their activities, and the network structure. The results raised issues that will be used to refine our approach in the future.
Joint Range and Load Considerations for Topology Control in Wireless Ad Hoc Networks

Wireless ad hoc networks are usually composed of tiny and resource constraint devices, which make energy conservation a vital concern of their design. Reducing energy consumption has been addressed through different aspects till now. Topology control (TC) is a well-known approach which tries to assign the transmission ranges of nodes to optimize energy utilization while keeping some network properties like connectivity. However, in current TC schemes, the transmission range of each node is mostly accounted as the exclusive estimator for its energy consumption, while ignoring the amount of data it sends or relays. In this paper, we redefine the problem of topology control regarding both traffic load and transmission range parameters. After proving the NP-hardness of the new problem, we mathematically formulate it as a mixed integer linear programming problem to find the optimal solutions. Then, we introduce two polynomial-time heuristic algorithms to practically solve the problem. Finally, we show the advantages of our proposals through simulations
The HBP1 Transcriptional Repressor Participates in RAS-Induced Premature Senescence

ABSTRACT Oncogene-mediated premature senescence has emerged as a potential tumor-suppressive mechanism in early cancer transitions. Previous work shows that RAS and p38 MAPK participate in premature senescence, but transcriptional effectors have not been identified. Here, we demonstrate that the HBP1 transcriptional repressor participates in RAS- and p38 MAPK-induced premature senescence. In cell lines, we had previously isolated HBP1 as a retinoblastoma (RB) target but have determined that it functions as a proliferation regulator by inhibiting oncogenic pathways as a transcriptional repressor. In primary cells, the results indicate that HBP1 is a necessary component of premature senescence by RAS and p38 MAPK. Similarly, a knockdown of WIP1 (a p38 MAPK phosphatase) induced premature senescence that also required HBP1. Furthermore, HBP1 requires regulation by RB, in which few transcriptional regulators for premature senescence have been shown. Together, the data suggest a model in which RAS and p38 MAPK signaling engage HBP1 and RB to trigger premature senescence. As an initial step toward clinical relevance, a bioinformatics approach shows that the relative expression levels of HBP1 and WIP1 correlated with decreased relapse-free survival in breast cancer patients. Together, these studies highlight p38 MAPK, HBP1, and RB as important components for a premature-senescence pathway with possible clinical relevance to breast cancer.
Switchable genetic oscillator operating in quasi-stable mode

Ring topologies of repressing genes have qualitatively different long-term dynamics if the number of genes is odd (they oscillate) or even (they exhibit bistability). However, these attractors may not fully explain the observed behaviour in transient and stochastic environments such as the cell. We show here that even repressilators possess quasi-stable, travelling wave periodic solutions that are reachable, long-lived and robust to parameter changes. These solutions underlie the sustained oscillations observed in even rings in the stochastic regime, even if these circuits are expected to behave as switches. The existence of such solutions can also be exploited for control purposes: operation of the system around the quasi-stable orbit allows us to turn on and off the oscillations reliably and on demand. We illustrate these ideas with a simple protocol based on optical interference that can induce oscillations robustly both in the stochastic and deterministic regimes.
Biased Support Vector Machine with Self-Constructed Universum for PU Learning

In this paper, we proposed a biased support vector machine (Biased-SVM) with self-constructed Universum (termed as U-BSVM) to solve the PU learning problem. We first treat the PU problem as an imbalanced binary classification problem by labeling all the unlabeled inputs as negative with noise, then inspired by the Universum-SVM (U-SVM), introduce the Universum data set which is constructed from the original dataset to improve the performance of Biased-SVM. We intent to use the constructed Universum data set to catch some prior information of the ground-truth decision boundary. Obviously, different Universum data set leads to different result, so several methods to construct the appropriate Uninversum data set are also compared and suggested. Experiment results show the efficiency of our method for PU learning problem.
Toward Optimal Complete Exchange on Wormhole-Routed Tori

In this paper, we propose new routing schemes to perform all-to-all personalized communication (or known as complete exchange) in wormhole-routed, one-port tori. On tori of equal size along each dimension, our algorithms use both asymptotically optimal startup and transmission time. The results are characterized by several interesting features: (1) the use of gather-scatter tree to achieve optimality in startup time, (2) enforcement of shortest paths in routing messages to achieve optimality in transmission time, (3) application of network-partitioning techniques to reduce the constant associated with the transmission time, and (4) the dimension-by-dimension and gather-scatter-tree approach to make possible applying the results to nonsquare, any-size tori. In the literature, some algorithms are optimal in only one of startup and transmission costs, while some, although asymptotically optimal in both costs, will incur much larger constants associated with the costs. Numerical analysis and experiment both show that significant improvement can be obtained by our scheme on total communication latency over existing results.
Urban Transformation. From Public and Private Space to Spaces of Hybrid Character

The main characteristics of public space are accessibility and us- ability for all citizens. However, current developments, primarily observed in cities, suggest the loss of a clear distinction between public and private space. Instead, urban spaces of hybrid character are emerging. Spaces with public functions, like train stations, parks or pedestrian areas, are changing in char- acter, and semi-private spaces, like malls or plazas, are spreading. In order to get a realistic view of developments this article offers a critical appraisal of recent privatisation trends followed by a brief summary. After discussing feasible reasons for the loss of private space the article considers potential implications for the future of citizenship.
Memory fields of neurons in the primate prefrontal cortex.

Many prefrontal (PF) neurons convey information about both an object's identity (what) and its location (where). To explore how they represent conjunctions of what and where, we explored the receptive fields of their mnemonic activity (i.e., their "memory fields") by requiring monkeys to remember both an object and its location at many positions throughout a wide portion of central vision. Many PF neurons conveyed object information and had highly localized memory fields that emphasized the contralateral, but not necessarily foveal, visual field. These results indicate that PF neurons can simultaneously convey precise location and object information and thus may play a role in constructing a unified representation of a visual scene.
An Osteoconductive Antibiotic Bone Eluting Putty with a Custom Polymer Matrix

With the rising tide of antibiotic resistant bacteria, extending the longevity of the current antibiotic arsenal is becoming a necessity. Developing local, controlled release antibiotic strategies, particularly for difficult to penetrate tissues such as bone, may prove to be a better alternative. Previous efforts to develop an osteoconductive local antibiotic release device for bone were created as solid molded composites; however, intimate contact with host bone was found to be critical to support host bone regrowth; thus, an osteocondconductive antibiotic releasing bone void filling putty was developed. Furthermore, a controlled releasing polymer matrix was refined using pendant-functionalized diols to provide tailorable pharmacokinetics. In vitro pharmacokinetic and bioactivity profiles were compared for a putty formulation with an analogous composition as its molded counterpart as well as four new pendant-functionalized polymers. A best-fit analysis of polymer composition in either small cylindrical disks or larger spheres revealed that the new pendant-functionalized polymers appear to release vancomycin via both diffusion and erosion regardless of the geometry of the putty. In silico simulations, a valuable technique for diffusion mediated controlled release models, will be used to confirm and optimize this property.
An evaluation of the mental status of rejected asylum seekers in two Danish asylum centers.

INTRODUCTION International studies have shown high incidences of symptoms regarding anxiety, depression, and post traumatic stress disorder (PTSD) among asylum seekers of different ethnicities. The aim of the present study was to investigate the presence of symptoms of anxiety, depression, and PTSD among rejected Iraqi asylum seekers in two Danish Red Cross asylum centers. Factors such as the length of stay in an asylum center and the number of traumatic events were considered as risk factors associated with the degree of psychological morbidity. METHOD In 2007, 53 rejected Iraqi asylum seekers from two Danish Red Cross centers completed a survey based on the Harvard Trauma Questionnaire-IV (HTQ) and the Hopkins Symptom Checklist 25 (HSCL-25). The response rate was 36%. The analyses focused on the impact of gender, age, marriage, religion, the length of stay at the asylum center, and the number of traumatic events on the severity of symptoms of anxiety, depression, and PTSD. FINDINGS Of all participants, 94% were found to have symptoms of anxiety, 100% had symptoms of depression, and 77% had symptoms of PTSD. The participants had experienced or witnessed an average of 8.5 traumatic events before their arrival in Denmark. There was no significant association between the number of traumatic events, and the symptoms of PTSD. In addition, there was no significant difference in the length of stay and symptoms of anxiety, depression, and PTSD despite the fact that 79% of the participants had stayed in an asylum center for 5-10 years or more. CONCLUSION Despite the limitations of the data, such as the small sample, this study showed that the prevalence rates of psychopathology in Iraqi asylum seekers in Denmark were alarmingly high. Therefore, it is recommended that systematic screening of all detained asylum seekers in Denmark is introduced. Given the degree of mental health problems it is also recommended that procedures be changed and that treatment should be offered to asylum seekers who are detained in Danish asylum centers.
Structural basis for selective targeting of leishmanial ribosomes: aminoglycoside derivatives as promising therapeutics

Leishmaniasis comprises an array of diseases caused by pathogenic species of Leishmania, resulting in a spectrum of mild to life-threatening pathologies. Currently available therapies for leishmaniasis include a limited selection of drugs. This coupled with the rather fast emergence of parasite resistance, presents a dire public health concern. Paromomycin (PAR), a broad-spectrum aminoglycoside antibiotic, has been shown in recent years to be highly efficient in treating visceral leishmaniasis (VL)—the life-threatening form of the disease. While much focus has been given to exploration of PAR activities in bacteria, its mechanism of action in Leishmania has received relatively little scrutiny and has yet to be fully deciphered. In the present study we present an X-ray structure of PAR bound to rRNA model mimicking its leishmanial binding target, the ribosomal A-site. We also evaluate PAR inhibitory actions on leishmanial growth and ribosome function, as well as effects on auditory sensory cells, by comparing several structurally related natural and synthetic aminoglycoside derivatives. The results provide insights into the structural elements important for aminoglycoside inhibitory activities and selectivity for leishmanial cytosolic ribosomes, highlighting a novel synthetic derivative, compound 3, as a prospective therapeutic candidate for the treatment of VL.
Effects of Mass Layer Stiffness and Imperfect Bonding on a Quartz Crystal Microbalance

We study free vibrations of a crystal plate of AT-cut quartz carrying a thin mass layer operating as a quartz crystal microbalance for mass sensing. The mass layer is imperfectly bonded to the crystal plate with its interface described by the so-called shear-slip model that allows a discontinuity of the interface displacement. The effect of mass layer in-plane shear stiffness is also considered. The equations of anisotropic elasticity are used for the crystal plate with the omission of the small elastic constant c56. The mass layer is governed by the plane-stress equations of elasticity. An analytical solution is obtained using Fourier series, from which the resonant frequencies and vibration mode shapes are calculated. The effects of the mass layer in-plane shear stiffness, imperfect interface bonding on resonant frequencies and energy trapping are examined.
Reusing Ontological Background Knowledge in Semantic Wikis

A number of approaches have been developed for combining wikis with semantic technologies. Many semantic wikis focus on enabling users to specify properties and relationships of individual elements. Complex schema information is typically not edited by the wiki user. Nevertheless, semantic wikis could benefit from taking existing schema information into account, and to allow users to specify additional information based on this schema. In this paper, we introduce an extension of Semantic MediaWiki that incorporates schema information from existing OWL ontologies. Based on the imported ontology, the system offers automatic classification of articles and aims at supporting the user in editing the wiki knowledge base in a logically consistent manner. We present our prototype implementation which uses the KAON2 ontology management system to integrate reasoning services into our wiki.
Coordination and Control in Mobile Ubiquitous Computing Applications Using Law Governed Interaction

This paper introduces a mechanism for regulating the interactions between the members of an ad hoc, heterogeneous and mobile multi-agent system, in order to ensure reliable and secure coordination between them. We demonstrate this mechanism, and its importance, by describing its application to a police team whose mission is to manage (i.e., monitor and control) the traffic in an area, by operating on a set of traffic-related devices, such as draw bridges, traffic lights, and road blocks. In particular, we demonstrate how the following critical aspects of the working of such a team are provided for: a) reliable coordination between the team members; b) the ability of the leader of the team to steer its subordinates; c) reliable auditing of the operations of the team; and d) robustness of the team under certain unexpected adverse conditions, such as the unpredictable failure of the team leader. Beyond developing suitable formalisms for local regulation of actions and communications, performance tests have been conducted with the proposed implementation on the ORBIT testbed and the results presented show the viability of this approach. Keywords-Law Governed Interaction; ad hoc coordination; decentralized enforcement; security
Carbon nanotube composites for thermal management

Single-wall carbon nanotubes (SWNTs) were used to augment the thermal transport properties of industrial epoxy. Samples loaded with 1 wt % unpurified SWNT material showed a 70% increase in thermal conductivity at 40 K, rising to 125% at room temperature; the enhancement due to 1 wt % loading of vapor grown carbon fibers was three times smaller. Electrical conductivity data showed a percolation threshold between 0.1 and 0.2 wt % SWNT loading. The Vickers hardness rose monotonically with SWNT loading up to a factor of 3.5 at 2 wt %. These results suggest that the thermal and mechanical properties of SWNT-epoxy composites are improved, without the need to chemically functionalize the nanotubes.
Generalizations of Watched Literals for Backtracking Search

The technique of watching two literals per clause to determine when a clause becomes a unit clause was introduced recently in the Chaff satisfiability program. That program does not perform either equivalent-literal detection or binary-clause detection. We describe a generalization of the technique that handles the tracking necessary to support equivalent-literal detection and binary-clause detection. Both generalizations are designed to preserve the important property of the original method that unbinding a variable is very efficient. We decribe a data-structure technique called “lazy deletion” that permits several operations to be performed in amortized constant time, where the more straightforward implementation might require linear time per operation. The overall efficiency of generalized technique is analyzed. Preliminary implementation results are reported.
mTagATune: Mobile TagATune -- Audio Files Tagging Mobile Game

mTagATune is a mobile application based on TagATune [9] and developed in JAVA for Android cell phones. mTagATune implements the concept of GWAP [2] and seizes the capabilities and wide acceptance of current smart phones. GWAP promotes the creation of computer games that encourage people to do voluntary work. mTagATune implements a game that collects information on audio files to facilitate future searches on them. By means of a collaborative game, mTagATune enables an ubiquitous collection of information on audio files that can later be used in search results.
An independent software system for the analysis of dynamic MR images

Purpose: A computer system for the manual, semi-automatic, and automatic analysis of dynamic MR images was to be developed on UNIX and personal computer platforms. The system was to offer an integrated and standardized way of performing both image processing and analysis that was independent of the MR unit used. Material and Methods: The system consists of modules that are easily adaptable to special needs. Data from MR units or other diagnostic imaging equipment in techniques such as CT, ultrasonography, or nuclear medicine can be processed through the ACR-NEMA/DICOM standard file formats. A full set of functions is available, among them cine-loop visual analysis, and generation of time-intensity curves. , Parameters such as cross-correlation coefficients, area under the curve, peak/maximum intensity, wash-in and wash-out slopes, time to peak, and relative signal intensity/contrast enhancement can be calculated. Other parameters can be extracted by fitting functions like the gamma-variate function. Region-of-interest data and parametric values can easily be exported. Results and Conclusion: The system has been successfully tested in animal and patient examinations.