Miracle-dz/UniFAR-FTUs huggingface dataset:
Heart Rate, Recall, and Reaction-Time Measures of Levels of Processing

A problem of circularity emerges in any attempt to index depth by retention alone. In the present study, reaction time (RT), and heart-rate response were used to index the three qualitatively distinct levels of physical, phonemic, and semantic processing. An additional objective was to distinguish between the three levels under incidental vs intentional learning conditions. Subjects were 46 male undergraduates who were given 30 trials. A trial consisted of the presentation of an orienting question and an imperative word-stimulus separated by a 6-sec. interval. There were three types of questions in order to induce processing to one of the three target levels. The results indicated that recall as well as heart-rate acceleration distinguished between two (physical vs phonemic and semantic) rather than three levels of processing in the incidental condition. Heart-rate change differentiated between incidental and intentional, the intentional condition showing a smaller change. Semantic and phonemic RTs were faster than physical RT, but there were no differences between semantic and phonemic RTs. Intentional recall was superior to incidental recall. It is suggested that psychophysiological indices can provide independent evidence for ‘levels of processing. ’
Heteromeric interactions regulate butyrophilin (BTN) and BTN-like molecules governing γδ T cell biology

Significance Although gamma delta (γδ) T cells compose an evolutionarily conserved third lineage of diversified lymphocytes, alongside αβ T cells and B cells, they can seem overtly different across species and tissues. Thus, human blood γδ cells show butyrophilin (BTN)3A1-dependent responses to metabolites (“phosphoantigens”) not seen by rodent γδ cells, whereas some rodent, γδ-rich compartments, notably in the skin, lack obvious human counterparts. Recently, however, mouse and human intraepithelial gut γδ cells were found to be regulated by pairings of BTN-like genes. This study now shows that BTN3A1 also functions as a pairing, with its subcellular trafficking and optimal activity both regulated by BTN3A2. Hence, seemingly diverse γδ cell biologies across species and tissues are underpinned by conserved mechanisms. The long-held view that gamma delta (γδ) T cells in mice and humans are fundamentally dissimilar, as are γδ cells in blood and peripheral tissues, has been challenged by emerging evidence of the cells’ regulation by butyrophilin (BTN) and butyrophilin-like (BTNL) molecules. Thus, murine Btnl1 and the related gene, Skint1, mediate T cell receptor (TCR)-dependent selection of murine intraepithelial γδ T cell repertoires in gut and skin, respectively; BTNL3 and BTNL8 are TCR-dependent regulators of human gut γδ cells; and BTN3A1 is essential for TCR-dependent activation of human peripheral blood Vγ9Vδ2+ T cells. However, some observations concerning BTN/Btnl molecules continue to question the extent of mechanistic conservation. In particular, murine and human gut γδ cell regulation depends on pairings of Btnl1 and Btnl6 and BTNL3 and BTNL8, respectively, whereas blood γδ cells are reported to be regulated by BTN3A1 independent of other BTNs. Addressing this paradox, we show that BTN3A2 regulates the subcellular localization of BTN3A1, including functionally important associations with the endoplasmic reticulum (ER), and is specifically required for optimal BTN3A1-mediated activation of Vγ9Vδ2+ T cells. Evidence that BTNL3/BTNL8 and Btnl1/Btnl6 likewise associate with the ER reinforces the prospect of broadly conserved mechanisms underpinning the selection and activation of γδ cells in mice and humans, and in blood and extralymphoid sites.
Cooperative hybrid control of robotic sensors for perimeter detection and tracking

In this paper, we present a decentralized coordination algorithm that allows a robotic swarm to locate and track a dynamic perimeter. A cooperative communication scheme is used by the team to rapidly detect a perimeter. Collision-free cycling behavior emerges by composing simple reactive control laws. The decentralized framework could potentially allow the algorithm to scale to many robots. Extensive simulation results and experiments verify the validity and scalability of the proposed cooperative control scheme.
The possible clinical impact of risperidone on P‐glycoprotein‐mediated transport of tacrolimus: A case report and in vitro study

The authors encountered the case of an 8‐fold increase in the concentration/dose (C/D) ratio of tacrolimus (TAC) following the coadministration of voriconazole (VRCZ) in a hematopoietic stem cell transplantation (HSCT) recipient. The interaction observed was much greater than expected and the patient had also been treated with oral risperidone (RSP). It was hypothesized that cytochrome P450 (CYP)3A inhibition of the small intestine by voriconazole and P‐glycoprotein (P‐gp) inhibition of the small intestine by risperidone exerted a synergistic effect on the bioavailability of tacrolimus. The aim of the present study was to evaluate the effect of risperidone on the P‐gp‐mediated transport of tacrolimus. The transcellular transport of P‐gp substrates was examined in Caco‐2 and P‐gp‐expressing renal epithelial LLC‐GA5‐COL150 cells. In Caco‐2 cells, the apical‐basal (A‐B) transport of rhodamine123 (Rh123) after a 120 min incubation was increased by 47.1%, whereas that in the B‐A direction was decreased by 61.7% in the presence of risperidone (100 μm). These results indicate that risperidone showed an inhibitory effect on the P‐gp‐mediated transport of Rh123. In LLC‐GA5‐COL150 cells, the A‐B transport of tacrolimus after 120 min incubation was increased by 21.7% in the presence of risperidone (100 μm), whereas that in the B‐A direction was decreased by 10.7%. These results suggest that risperidone was at least partly involved in the mechanism of the marked increase in the C/D ratio of tacrolimus. This case report provides new insights into the diversity of drug interactions of tacrolimus triggered by the combination of two concomitant drugs.
Pork price transmission and efficiency in China

Based on monthly prices data from retail markets from 2000 to 2015, this article studies spatial transmission of piglet,hog and pork, and also the determinants and efficiency of pork price transmission in China. A vector error correction model (VECM) and stochastic frontier model are estimated.The estimated VECM shows that violations of spatial price equilibrium are corrected faster between provinces in close proximity. The stochastic frontier shows that price transmission is more efficient between provinces with closer distance, common borders , higher quantity of highway per capita and more production. The distance makes the highest contribution to pork price transmission efficiency, a 1 % change in distance between two provincial markets, a 9.33% growth in price transmission efficiency. We conclude that proximity matters for market integration processes in Chinese pork markets. Acknowledgement :
[Hospital anxiety and depression].

OBJECTIVE The study investigate the presence of depressive disorders in patient who are taken in general hospital, to prevent and reduce the risk of developing a psychological pathology (anxious-depressive symptoms). METHODS We used two tests: 1. General Health Questionnaire (GHQ-12) by Goldberg, a self-report questionnaire, consisting of 12 items, used to estimate the probability of detecting non-psychotic mental disorders and problems in every day's activity. 2. Personal Health Questionnaire (PHQ), a self-report questionnaire, consisting of 10 items. It is a new tool for detecting individuals with ICD-10 depressive disorders, used to estimate the probability to individuate the presence of major depression symptoms, and minor depression symptoms. Tests have been administered to 140 subjects (males' experimental group, 32 subjects; males' control group, 20 subjects; females' experimental group 58 subjects; females' control group, 30 subjects) from eight departments of university hospital, medical faculty, and social services. RESULTS It can be noted that with GHQ-12, the presence of non-psychotic mental disorders does not come out: just the females' group, experimental and control, shows some problems with insomnia and stress. On the other hand, with PHQ, the presence of no great entity depressive symptoms comes out for all groups. In the experimental groups the quantity of depressive symptoms is greater than in the control groups. CONCLUSIONS We have find the presence of a number of depressive symptoms into a hospitalized population. It is known that detecting such symptoms is important for protection and care of depressive disorders in hospitalized and non-hospitalized populations.
Reduction in Head and Intervertebral Motion Provided by 7 Contemporary Cervical Orthoses in 45 Individuals

Study Design. Biomechanical evaluation of cervical orthoses. Objective. To provide data to help clinicians select an orthosis for immobilization of the adult cervical spine. Summary of Background Data. There are limited data on the effectiveness of cervical orthoses at restricting intervertebral motion, and many of the commonly used, contemporary braces have not been evaluated. Additionally, no data exist comparing the effectiveness of braces in the supine versus the upright position. New technology is available to measure intervertebral motion with greater accuracy. Methods. Overall range of motion of the head in 3 planes as well as intervertebral motion in the sagittal plane were measured in 45 healthy adult volunteers while wearing 7 cervical orthoses. Subject-reported comfort of each brace was also recorded. Results. All braces significantly reduced intervertebral motion. Effectiveness and comfort varied between braces. In general, orthoses could be grouped as cervical braces or cervicothoracic braces. The latter was consistently better at limiting motion, with some differences within these groups as well. Conclusion. These data will help to guide the clinician in selecting the appropriate cervical orthosis for their adult patient based on comfort, morphologic considerations, and degree of immobilization required.
Bulimia nervosa: an ominous variant of anorexia nervosa

Synopsis Thirty patients were selected for a prospective study according to two criteria: (i) an irresistible urge to overeat (bulimia nervosa), followed by self-induced vomiting or purging; (ii) a morbid fear of becoming fat. The majority of the patients had a previous history of true or cryptic anorexia nervosa. Self-induced vomiting and purging are secondary devices used by the patients to counteract the effects of overeating and prevent a gain in weight. These devices are dangerous for they are habit-forming and lead to potassium loss and other physical complications. In common with true anorexia nervosa, the patients were determined to keep their weight below a self-imposed threshold. Its level was set below the patient‘s healthy weight, defined as the weight reached before the onset of the eating disorder. In contrast with true anorexia nervosa, the patients tended to be heavier, more active sexually, and more likely to menstruate regularly and remain fertile. Depressive symptoms were often severe and distressing and led to a high risk of suicide. A theoretical model is described to emphasize the interdependence of the various symptoms and the role of self-perpetuating mechanisms in the maintenance of the disorder. The main aims of treatment are (i) to interrupt the vicious circle of overeating and self-induced vomiting (or purging), (ii) to persuade the patients to accept a higher weight. Prognosis appears less favourable than in uncomplicated anorexia nervosa.
Effects of Pulsed Electric Fields on Pathogenic Microorganisms of Major Concern in Fluid Foods: A Review

Pathogenic microorganisms such as Escherichia coli O157:H7, Salmonella spp. , Listeria monocytogenes, Bacillus cereus, Staphylococcus aureus, Yersinia enterocolitica, and Campylobacter jejuni have been implicated in foodborne diseases and outbreaks worldwide. These bacteria have been associated with the consumption of fresh fruit juices, milk, and dairy products, which are foodstuff, highly demanded by consumers in retails and supermarkets. Nowadays, consumers require high quality, fresh-like, and safe foods. Pulsed electric field (PEF) is a non-thermal preservation method, able to inactivate pathogenic microorganisms without significant loss of the organoleptic and nutritional properties of food. The PEF treatment effectiveness to destroy bacteria such as Listeria innocua, E. coli, Salmonella Typhimurium, E. coli O157:H7 and E. coli 8739 at pasteurization levels (≥ 5.0 log10 cycles) in some fluid foods was reported. However, data on the inactivation of some microorganisms such as Bacillus cereus, Staphylococcus aureus, Yersinia enterocolitica, and Campylobacter jejuni in fluid foods by PEF processing is very limited. Therefore, future works should be focused toward the inactivation of these pathogenic bacteria in real foods.
To know what they are doing in a web-based laboratory, a system for saving information on the learners' activities into Sakai's logs

Tools utilizing the web-server's logs for monitoring and analyzing the users' behavior are used in many fields where the Internet plays a major role as in e-commerce and e-learning. These tools are very useful for tracking the learning activities of the students in web-based Course Management Systems (CMS). While the logs can be customized to include much information on what goes-on in the CMS, they include very little or nothing about any external web application/laboratory that might be linked with it. Such information would give the instructors an idea of how students manage their knowledge and skills to complete the tasks assigned to them. This contribution comes to show how within the web-based laboratory (NVLab) that we designed for supporting Information and Communication Technologies (ICT) courses delivered in Sakai Collaboration and Learning Environment (CLE) we handled this issue by developing a system for saving information on learners' activities in the log of the web server. This system successfully uses Sakai web-services technology to save information starting from the time the learner accessed our premises until what he/she typed.
Spectroscopic Noninvasive Measurement of Hemoglobin Compared with Capillary and Venous Values in Neonates

Background: Venepuncture-related blood loss is a common cause of neonatal anemia. Currently, this is the only way to obtain hemoglobin levels. This causes distress for the infant but can also lead to the need for blood transfusions. Recently, a new technique for measuring hemoglobin levels non-invasively has been developed to reduce iatrogenic blood loss and pain. Objective: To compare hemoglobin levels obtained using a transcutaneous spectroscopic device (Mediscan 2000, MBR Optical Systems, Wuppertal, Germany) with venous or capillary blood samples in neonates. Methods: Single-center prospective cohort study of term and preterm infants. The white light spectroscopic device was placed on the forearm for 60 s to measure hemoglobin content within 4 h of venous or capillary blood sampling. Pain reactions of the infants were assessed by using a neonatal pain assessment tool. Results were analyzed by Bland-Altman comparison and Wilcoxon signed-rank test. Results: 80 infants (mean gestational age 29.8 ± 3.8 weeks, mean birth weight 1,300 ± 690 g) were enrolled into the study. A total of 313 spectroscopic recordings within 2 h of a clinically indicated blood sample (181 capillary, 142 venous) were taken. The correlation coefficient R2 was 0.96 for capillary/spectroscopic and 0.99 for venous/spectroscopic pairs. Pain scores were significantly less for the spectroscopic measurements (p < 0.01). Conclusion: The results show good correlation between the hemoglobin blood levels and spectroscopic measurements. The slightly lower correlation coefficient for the capillary samples demonstrates a naturally higher variance in these values due to the laboratory method.
Classification of high dimensional data using LASSO ensembles

The estimation of multivariable predictors with good performance in high dimensional settings is a crucial task in biomedical contexts. Usually, solutions based on the application of a single machine learning model are provided while the use of ensemble methods is often overlooked within this area despite the well-known benefits that these methods provide in terms of predictive performance. In this paper, four ensemble approaches are described using LASSO base learners to predict the vital status of a patient from RNA-Seq gene expression data. The results of the analysis carried out in a public breast invasive cancer (BRCA) dataset shows that the ensemble approaches outperform statistically significant the standard LASSO model considered as baseline case. We also perform an analysis of the computational costs involved for each of the approaches, providing different usage recommendations according to the available computational power.
Comparison of yield components and quality factors of sweet corn under different irrigation scheduling strategies

Rising energy costs, declining groundwater supplies, increasing competition for water resources between agricultural, industrial and domestic users and irrigation-induced water quality problems are providing considerable impetus to improving efficiency in irrigated agriculture. Much of the groundwater used for irrigation is found in closed underground basins. Water percolation is the only source of water available for recharge. In some basins, the pumping rate is much greater than the recharge from percolation and ‘water mining’ occurs. The aim of this study was to compare the yield components and quality factors of sweet corn grown under different irrigation scheduling strategies. The treatment with 426 mm of seasonal irrigation offered the largest commercial yields, with an appropriate quality production, good irrigation efficiency, the highest gross margin and the best break-even point irrigation strategy. Treatments with higher application produced lower irrigation efficiencies.
Prison Governors as Policymakers, Phronetic Practices as Enacted Knowledge

In the last 15 years, Belgian prisons have been characterised by an increase of managerial and legal regulations. Building on an empirical account of prison governors&#8217; work practices and bureaucratic working context, this article shows how the rise of policy inscriptions paradoxically leads to a sharper need of prison governors for practical knowledge. Drawing on four years of qualitative research with 40 Belgian prison governors, the article illustrates how they define &#8216;ethical dilemmas&#8217; &#8211; that is, uncertain and ambiguous events &#8211; and reach a particular decision. Two analytical concepts are used in that respect. First, the concept of &#8216;phronetic practices&#8217; (Nonaka and Takeuchi 2011) relates to the practical knowledge used to make decisions in uncertain and ambiguous situations. Second, the concept of &#8216;enacted knowledge&#8217; (Freeman and Sturdy 2015) enlightens how such decisions contribute to shaping prison policy, organisations, and administration. In that perspective, this article proposes to recognise the ethics of prison governors conceived as policymakers.
Oscillation power of opto-electronic oscillator limited by nonlinearities of mach-zehnder modulator and microwave amplifier

We proposed an analytical model to calculate the oscillation power of opto-electronic oscillator (OEO) considering the nonlinearities of both MZ-modulator and microwave amplifier. Compared with traditional models which do not consider the nonlinearity of the microwave amplifier, our model can predict the oscillation power more accurately under the condition that the nonlinearity of microwave amplifier is significant. Our experiments indicated that the saturated oscillating power predicted by our model is in consistent with the experimental data, while traditional model is about 10dB larger in the case that the microwave amplifier's nonlinearity is more significant than that of the MZ modulator.
Respiratory-chain enzyme activities in isolated mitochondria of lymphocytes from patients with Parkinson's disease: preliminary study.

BACKGROUND Evidence suggests that mitochondrial dysfunction stimulates the production of reactive oxygen species (ROS) that promote neural cell death in stroke and in Parkinson's disease. The sites of mitochondrial ROS production are not established but are generally believed to be located within the electron transport chain. AIMS We studied the mitochondrial respiratory chain enzymes function from human circulating lymphocytes. SETTING AND DESIGN Open study. MATERIALS AND METHODS Forty patients with Parkinson's disease (PD) with 30 age-matched control subjects were selected in this study. The patients had received no treatment before the study was conducted. STATISTICAL ANALYSIS The data from patients and controls were compared using two-tailed student's t-test and values were expressed as means +/- standard deviation (SD). RESULTS Respiratory complex I + III and IV activities were significantly lower (P < 0.001) in patients than in control subjects. CONCLUSIONS The use of lymphocytes for investigating the respiratory chain enzymes provides an easy, noninvasive method to assess mitochondrial function in patients with PD. Furthermore, our study supports the hypothesis that a biochemical defect in the respiratory chain may be involved in the pathogenesis of PD.
Halobacillus salinus sp. nov., isolated from a salt lake on the coast of the East Sea in Korea.

A Gram-positive, rod-shaped, endospore-forming, halophilic bacterium (strain HSL-3(T)) was isolated from a salt lake near Hwajinpo beach on the East Sea in Korea and was subjected to a polyphasic taxonomic study. Strain HSL-3(T) grew optimally in the presence of 2-10% (w/v) NaCl. Strain HSL-3(T) showed poor growth in the absence of NaCl and grew in the presence of less than 23% NaCl. The cell wall peptidoglycan type of strain HSL-3(T) was A4beta based on L-Orn-D-Asp. The predominant menaquinone found in strain HSL-3(T) was menaquinone-7 (MK-7). Strain HSL-3(T) had a cellular fatty acid profile containing large amounts of branched fatty acids; the major fatty acids were anteiso-C(15 : 0), iso-C(15 : 0) and iso-C(16 : 0). The DNA G + C content of strain HSL-3(T) was 45 mol%. Phylogenetic analysis based on 16S rDNA sequences showed that strain HSL-3(T) falls within the radiation of the cluster comprising Halobacillus species. Strain HSL-3(T) exhibited levels of 16S rDNA similarity of 97.4-98.4% to the type strains of Halobacillus species. Levels of DNA-DNA relatedness between strain HSL-3(T) and the type strains of all validly named Halobacillus species were in the range 7.3-9.2%. On the basis of phenotypic and phylogenetic data and the genomic distinctiveness, strain HSL-3(T) (= KCCM 41590(T) = JCM 11546(T)) should be placed in the genus Halobacillus as the type strain of a novel species, for which the name Halobacillus salinus sp. nov. is proposed.
Isolation enhancement between microstrip patch antennas using dual-band EBG structure without common ground plane

This paper presents an efficient method to enhance the isolation level between two dual-band E-shape microstrip patch antennas using dual-band EBG unit cells which operates in UMTS Tx (1.92-1.98GHz) and Rx (2.11-2.17GHz) band, respectively. The proposed EBG structure made with a periodic array of two different geometric dimensions of unit cell which has a modified mushroom-type. Overall size of the fabricated antenna is 210.5 mm × 117 mm. The fabricated two different EBG unit cell sizes are 15.6 mm × 4 mm and 17.4 mm × 4 mm, respectively. The experimental results show that the isolation levels between antennas in Tx/Rx band are under -35 dB.