Miracle-dz/UniFAR-FTUs huggingface dataset:
A framework of customer complaint handling system

An effect and efficient response to the complaints from customer is an essential indicator of a service-oriented company's performance, especially for a high-end restaurant chain group. Complaints reflect the needs for improvement for a restaurant, such as food taste, quality and quantity, speed of services, price, service attitude, decoration and environment factor, and sanitary factor. Customers have strong demands for quick responses to their complaints nowadays. The paper overcomes the deficient approach of current (as-is) complaint handling through process reengineering. In this study, a (to-be) framework of complaint handling system is analyzed and developed for a Japanese restaurant chain. The operations between the headquarter and branches are studied to show the benefits of proposed complaint handling process. In the first phase of the study, the as-is complaint reporting process is depicted. In the second phase, the to-be complaint handling model and its process are defined using a formal integrated process modeling (INCOME) approach. The new framework includes complaint reporting, compensation diagnosis, and complaint analysis. Furthermore, this paper also discusses the decision supports of complaint resolution automatically by the system and its benefit comparing to the current practices.
The Cantonese Hearing in Noise Test

Cantonese or Yue, is a form of Chinese that is spoken by over 65 million persons residing in Guangxi and Guangdong provinces and Hong Kong in China, Southeast Asia, Canada, the United States, and many other countries. The Cantonese hearing in noise test was developed immediately after the American English HINT was established. As this was the first sentence speech recognition material developed for use in an adaptive paradigm among tonal language speakers, two issues arose. The first was whether it is necessary to balance the occurrence of lexical tones across sentence lists, just as segmental phonemes are balanced across lists in non-tone languages; and the second issue was whether similar sentence structures and numbers of syllables as in the American English HINT would yield sentences with good intersubject variability. The following describes in brief the development of the Cantonese HINT and addresses these two issues; greater detail can be found in Wong and Soli (2005).
Survivin Expression as a Prognostic Factor in Patients With Epithelial Ovarian Cancer or Primary Peritoneal Cancer Treated With Neoadjuvant Chemotherapy

Background The aim of this study was to evaluate association of expression of survivin and p53 with the effects of neoadjuvant chemotherapy (NAC) in patients with advanced ovarian cancer (AOC). Methods We retrospectively evaluated 60 consecutive patients with AOC (International Federation of Gynecology and Obstetrics stage IIIC-IV) treated with NAC. The expression of p53 and survivin was assessed immunohistochemically. The median of expression total score survivin equals 2 was adopted to dichotomize the group. The positive and negative expression of p53 was used to dichotomize the group. Results The expression of survivin in tumor tissue taken before and after NAC was a significant difference in the percentage of stained nuclei (P = 0.0002), the intensity of staining (P = 0.0003), and total score (P = 0.0001). There was a significant difference in p53 expression in tumor tissue before and after NAC in the percentage of stained nuclei (P = 0.0424). Survivin expression, in contrast to p53 expression, was a prognostic factor in patients with AOC treated with NAC (P = 0.0484). The expression of survivin and p53 was not a predictive factor. Independent adverse predictor factors were as follows: lack of optimal interval debulking surgery and the lack of an objective response (the respective hazard ratio was 3.93 [95% confidence interval, 2.07–7.46; P < 0.0001] and 2.36 [95% confidence interval,1.25–4.47; P = 0.0080]). The suboptimal range of interval debulking surgery, resistance to platinum, and the lack of paclitaxel in the NAC were adverse prognostic factors (the respective hazard ratio was 2.61 [95% confidence interval, 1.17–5.83], 2.72 [95% confidence interval, 1.07–6.89], and 2.56 [95% confidence interval, 1.06–6.18]; P < 0.05]). Conclusions High expression of survivin could be a prognostic factor in patients treated with NAC for AOC.
Most Influential Community Search over Large Social Networks

Detecting social communities in large social networks provides an effective way to analyze the social media users' behaviors and activities. It has drawn extensive attention from both academia and industry. One essential aspect of communities in social networks is outer influence which is the capability to spread internal information of communities to external users. Detecting the communities of high outer influence has particular interest in a wide range of applications, e.g., Ads trending analytics, social opinion mining and news propagation pattern discovery. However, the existing detection techniques largely ignore the outer influence of the communities. To fill the gap, this work investigates the Most Influential Community Search problem to disclose the communities with the highest outer influences. We firstly propose a new community model, maximal kr-Clique community, which has desirable properties, i.e., society, cohesiveness, connectivity, and maximum. Then, we design a novel tree-based index structure, denoted as C-Tree, to maintain the offline computed r-cliques. To efficiently search the most influential communities, we also develop four advanced index-based algorithms which improve the search performance of non-indexed solution by about 200 times. The efficiency and effectiveness of our solution have been extensively verified using six real datasets and a small case study.
Transgenesis by lentiviral vectors: Lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos

The introduction of foreign genes into early mouse embryos and embryonic stem (ES) cells is invaluable for the analysis of gene function and regulation in the living animal. The use of vectors derived from retroviruses as gene transfer vehicles in this setting has had limited success because of silencing of transgene expression. Here, we show that vectors derived from lentiviruses, which are complex retroviruses, can efficiently deliver genes to murine ES cells and that transgene expression is stable during proliferation of undifferentiated ES cells. The transgene is expressed during differentiation of ES cells in vitro (embryoid bodies) and in vivo (teratomas). Transfer of lentivector-transduced ES cells into blastocysts resulted in chimeric animals that expressed the transgene in multiple tissues. Embryos derived from crossings of chimeric mice expressed the transgene, indicating successful germ-line transmission. Infection of murine preimplantation embryos at morula stage with lentiviral vectors resulted in stable transduction and expression of the transgene in mouse embryos and in newborn mice. Finally, human ES cells were transduced by lentiviral vectors and expressed the transgene over several passages. Thus, lentiviral vectors represent a significant improvement over oncoretroviral vectors used previously for gene transfer into murine ES cells and preimplantation embryos. Ability to transfer foreign genes into human ES cells has potential relevance for the development of gene and cell-based therapies.
Laparoscopic Resection of Rectal Cancer Results in Higher Lymph Node Yield and Better Short-term Outcomes Than Open Surgery: A Large Single-Center Comparative Study

BACKGROUND: Prognosis in rectal cancer is closely related to mesorectal integrity, margin status, and adequate lymph node dissection. The impact of laparoscopy on the pathologic and short-term outcomes remains controversial. OBJECTIVE: We aim to compare the pathologic and short-term outcomes of laparoscopic and open resections for rectal cancer. DESIGN: This is a large single-center retrospective comparative study using a prospective database. PATIENTS: All patients who underwent primary resections for rectal cancer from January 2007 to September 2011 were identified. MAIN OUTCOME MEASURES: Pathologic (nodal harvest, mesorectal integrity, circumferential, and distal margins) and operative outcomes were measured. RESULTS: Two hundred thirty-four (mean age, 61 years; 65% male) patients underwent resections for primary rectal cancer, including 118 laparoscopic (99 restorative proctectomies, 19 abdominoperineal resections) and 116 open (69 restorative proctectomies, 47 abdominoperineal resections) resections. Both groups were similar in demographics, comorbidities, and tumor characteristics. The laparoscopic group had significantly more lymph nodes (26 vs 21, p = 0.02) than the open group, with no differences in circumferential margins, proportion of distal resection margins <l cm, and completeness of total mesorectal excision. The impact of laparoscopic resection on lymph nodes was also observed for restorative proctectomy (27 vs 21, p = 0.03). Furthermore, obese and laparoscopic-converted patients had equivalent pathologic outcomes for laparoscopic and open resection. Laparoscopy was associated with longer operative time (245 vs 213 minutes, p = 0.002); less blood loss (284 vs 388 mL, p = 0.0l); shorter incisions (8 vs 20 cm, p = 0.0001) and hospital stay (7 vs 8 days, p = 0.05); and lower rates of 30-day morbidity (25% vs 43%, p = 0.04) and wound infections (9 vs 20%, p = 0.04). On multivariate regression, laparoscopic resection and year of surgery were the only independent predictors of greater lymph node harvest. CONCLUSIONS: Laparoscopy for primary rectal cancer is associated with a greater number of lymph nodes as well as short-term benefits.
The subparietal and parietooccipital sulci: An anatomical study

The subparietal and parietooccipital sulci are both located on the medial surface of the brain. Both of these sulci reveal significant variability in pattern and complexity. Both subparietal and parietooccipital sulci play an important role as surgical landmarks using posterior interhemispheric parietooccipital approach to lesions located adjacent to the ventricular trigon deep to the cingulate gyrus. The aim of this study is to analyze variations in the patterns of the subparietal and parietooccipital sulci and to emphasize their surgical importance. Fifty‐six formalin‐fixed cadaveric cerebral hemispheres from 28 adult humans are examined. Subparietal and parietal sulci patterns, variations and their relationship with the cingulate sulcus are studied according to the terminology introduced by Ono et al. The H‐pattern was observed in 50% (n = 28) of all hemispheres, being the most common pattern of the subparietal sulcus. The Straight pattern was observed in the 30.4% (n = 17) of all hemispheres, being the most common pattern of the parietooccipital sulcus. Furthermore, more detailed results among the patterns, connections, side branches and the relationship with the adjacent sulci are given. Our study further confirms the complexities in the patterns of the subparietal and parietooccipital sulci and demonstrates that these sulci fall within an expected range of variations. Better knowledge of these variations will further help neurosurgeons to navigate easily during approaches involving the medial surface of the parietal lobe. Clin. Anat. 26:667–674, 2013. © 2013 Wiley Periodicals, Inc.
Family support for heterosexual partners in HIV‐serodiscordant couples

ObjectiveTo ascertain the extent of family member support to heterosexual HIV-serodiscordant couples, and to identify associated sociodemographic and clinical characteristics. DesignDiscordant couples enrolled in a cohort study of heterosexual HIV transmission were interviewed with structured questionnaires to obtain sociodemographic data, family member awareness of HIV and perceived support from family members. Clinical characteristics were established by medical history, physical examination and laboratory tests. ResultsAwareness and support of family members were associated with sex of family member and HIV seropositivity, sex, education, and race of the partner. HIV-seropositive partners were more likely to have a sister aware than were HIV-negative partners (P =0.01). More educated HIV-positive partners had fewer aware family members than less educated HIV-positive individuals (P = 0.02). Mothers of HIV-positive women were more often aware than mothers of all other partners (P =0.04). Black HIV-negative partners had fewer aware family members than whites or Hispanics (P =0.02). ConclusionThis research shows both encouraging and disturbing patterns of family awareness of HIV and support to serodiscordant partners.
Calcium current during a single action potential in a large presynaptic terminal of the rat brainstem

1 The calcium current of a ‘giant’ synaptic terminal (the calyx of Held) was studied using two‐electrode voltage clamp in slices of the rat brainstem. 2 In terminals with a long axon (length > 100 μm), the passive current transient decayed bi‐exponentially following voltage steps. In terminals with a short axon (length < 30 μm), the slow component was reduced or absent. These terminals also had small slow calcium tail currents following long depolarizing voltage steps, suggesting that these are largely due to axonal calcium channels. 3 Terminals were voltage clamped with action potential waveform commands. At both 24 and 36°C the calcium current began shortly after the peak of the action potential and ended before the terminal was fully repolarized. 4 The calcium current during the repolarization phase was 69 ± 1 % (n= 3) of maximal, judged from the increase in this current when a plateau phase was added to the action potential waveform. 5 A Hodgkin‐Huxley m2 model, based on the measured activation and deactivation of the calcium current, reproduced both the time course and the amplitude increase of the calcium currents during the different action potential waveforms well. 6 The fast gating of the calcium channels in the terminal ensures that they are effectively opened during the repolarization phase of an action potential. This implies that the distance between open calcium channels is minimized, which is in agreement with the view that multiple calcium channels are needed to release a vesicle in this synapse.
Determining changes in NIR absorption using a layered model of the human head

A theoretical approach is presented to determine absorption changes in different compartments of a layered structure from distributions of times of flight of photons. In addition resulting changes in spatial profiles of time-integrated intensity and mean time of flight are calculated. The capability of a single-distance, time-domain method to determine absorption changes with depth resolution is tested on a layered phantom. We apply this method to in vivo measurements on the human head (motor stimulation, Valsalva manoeuvre) and introduce a small-sized time-domain experimental set-up suitable for bedside monitoring.
Cost-benefit analyses of the adoption of irrigation on oranges in São Paulo, Brazil

Brazil contributes 55% and 60% of the world’s production of fresh oranges and orange juice, respectively. In recent years, increasing production costs and low orange prices reduced the citrus producers’ profitability. In this paper we investigate the potential for irrigation to improve the profitability of orange production, using data from a sample of 98 citrus producers in the state of Sao Paulo, 34 of whom had adopted irrigation. Based on a translog production function, we use 3SLS to estimate a system of equations comprising the production function and the inverse derived demands for inputs, to obtain the impact of irrigation adoption on productivity. Results show that adopting irrigation increases citrus production by 19%. We estimate production elasticities of capital (.16), labor (.21), land (.26) and fertilizers (.20). We found that by considering yield increases versus both fixed and variable costs of implementation, farmers could expect to break even by the fifth year of irrigation use
Music therapy increases serum melatonin levels in patients with Alzheimer's disease.

CONTEXT Music therapy is known to have healing and relaxing effects. Although these effects appear to be mediated by release of neurotransmitters and neurohormones, the specific neurohormonal systems involved have not been fully investigated. OBJECTIVE To assess the effects of a music therapy intervention on concentrations of melatonin, norepinephrine, epinephrine, serotonin, and prolactin in the blood of a group of patients with Alzheimer's disease. DESIGN Blood samples were obtained before initiating the therapy, immediately at the end of 4 weeks of music therapy sessions, and at 6 weeks follow-up after cessation of the sessions. SETTING Miami Veterans Administration Medical Center, Miami, Fla. PATIENTS 20 male inpatients with Alzheimer's disease. INTERVENTION 30- to 40-minute morning sessions of music therapy 5 times per week for 4 weeks. MAIN OUTCOME MEASURES Changes in melatonin, norepinephrine, epinephrine, serotonin, and prolactin following music therapy. RESULTS Melatonin concentration in serum increased significantly after music therapy and was found to increase further at 6 weeks follow-up. A significant increase was found between baseline values and data recorded after the music therapy sessions as well as at 6 weeks follow-up. Norepinephrine and epinephrine levels increased significantly after 4 weeks of music therapy, but returned to pretherapy levels at 6 weeks follow-up. Serum concentration of prolactin and platelet serotonin levels remained unchanged after 4 weeks of music therapy and at 6 weeks follow-up. CONCLUSION Increased levels of melatonin following music therapy may have contributed to patients' relaxed and calm mood.
On DC Fault Dynamics of MMC-Based HVdc Connections

This paper studies the dc fault development stages and analyzes the fault dynamics in a point-to-point multilevel modular converters (MMC)-based dc connection. First, the effect of the dc grid configuration on the normal operation was investigated by comparing an asymmetric monopole with metallic return and a symmetric monopole. Then, the main parameters that affect the dc fault response of a grid, such as the fault type, impedance and converter blocking, were examined. Compared to previous studies, which are based on simulation results, the analysis is performed hereby both in theory, deriving the equations that describe the dc fault stages, as well as using experimental results obtained in the designed laboratory setup. The setup consists of two MMC terminals connected to two ac sources representing independent ac grids. These terminals are connected using a simple dc link based on pi-section equivalent of dc cables. The obtained results, which verified the theoretical analysis, can be used to determine the protection function thresholds of the MMC, as well as to estimate the developed stresses on dc lines during fault conditions and to define the design requirements for dc breakers.
Long-Term Employment and Job Security over the Past 25 Years

The authors document and contrast changes (or lack thereof) in job stability over the past 25 years between Japan and the United States. Prime-age male workers with at least five years of tenure in Japan continued to enjoy much higher job stability than did their U.S. counterparts. Most remarkably, Japan’s “Lost Decade” had little discernible adverse effect on the job stability of this group of Japanese employees. By contrast, job stability for mid-career hires and youth workers deteriorated in Japan. The authors’ cross-national regression analysis of job loss confirms the consistently more important role that seniority plays in protecting workers from job loss in Japan than in the United States and reveals that this gap in seniority’s influence on job stability between the two countries widened. Overall, it is the U.S. economy with the longest economic expansion, not the Japanese economy with the longest economic stagnation, that experienced deteriorating job stability, pointing to the absence of convergence of the Japanese and U.S. systems.
Pseudo-Outbreak of Extremely Drug-Resistant Pseudomonas aeruginosa Urinary Tract Infections Due to Contamination of an Automated Urine Analyzer

ABSTRACT By the end of May 2010, an increase in the number of urine specimens that were culture positive for extremely drug-resistant (XDR) Pseudomonas aeruginosa was observed in our 800-bed university hospital. This led to an infection control alert. No epidemiological link between the patients and no increase in the frequency of XDR P. aeruginosa in non-urine samples were observed. Therefore, a pseudo-outbreak due to analytical contamination in the laboratory was rapidly suspected. A prospective and retrospective search of cases was initiated, and the sampling of the automated urine analyzers used in the laboratory was performed. Antibiotypes were determined by disc diffusion, and genotypes were determined by pulsed-field gel electrophoresis (PFGE). From February to July 2010, 17 patients admitted to 12 different departments and 6 outpatients were included. The mixing device of the cytometric analyzer used for the numeration of urinary particles (Sysmex UF1000i) proved to be heavily contaminated. Isolates recovered from 12 patients belonged to the same antibiotype and PFGE type as the isolate recovered from the analyzer. Extensive disinfection with a broad-spectrum disinfectant and the replacement of the entire tubing was necessary to achieve the complete negativity of culture samples taken from the analyzer. A pseudo-outbreak caused by an XDR P. aeruginosa clone was proven to be due to the contamination of the cytometric analyzer for urinary sediment. Users of such analyzers should be aware that contamination can occur and should always perform culture either before the processing of the urine sample on the analyzer or on a distinct sample tube.
Analysis of Sequence, Map Position, and Gene Expression Reveals Conserved Essential Genes for Iron Uptake in Arabidopsis and Tomato1[w]

Arabidopsis (Arabidopsis thaliana) and tomato (Lycopersicon esculentum) show similar physiological responses to iron deficiency, suggesting that homologous genes are involved. Essential gene functions are generally considered to be carried out by orthologs that have remained conserved in sequence and map position in evolutionarily related species. This assumption has not yet been proven for plant genomes that underwent large genome rearrangements. We addressed this question in an attempt to deduce functional gene pairs for iron reduction, iron transport, and iron regulation between Arabidopsis and tomato. Iron uptake processes are essential for plant growth. We investigated iron uptake gene pairs from tomato and Arabidopsis, namely sequence, conserved gene content of the regions containing iron uptake homologs based on conserved orthologous set marker analysis, gene expression patterns, and, in two cases, genetic data. Compared to tomato, the Arabidopsis genome revealed more and larger gene families coding for the iron uptake functions. The number of possible homologous pairs was reduced if functional expression data were taken into account in addition to sequence and map position. We predict novel homologous as well as partially redundant functions of ferric reductase-like and iron-regulated transporter-like genes in Arabidopsis and tomato. Arabidopsis nicotianamine synthase genes encode a partially redundant family. In this study, Arabidopsis gene redundancy generally reflected the presumed genome duplication structure. In some cases, statistical analysis of conserved gene regions between tomato and Arabidopsis suggested a common evolutionary origin. Although involvement of conserved genes in iron uptake was found, these essential genes seem to be of paralogous rather than orthologous origin in tomato and Arabidopsis.