Miracle-dz/UniFAR-FTUs huggingface dataset:
The effect of grain source and grain processing on performance of feedlot cattle: a review.

Effects of grain species and grain processing method on DMI, rate and efficiency of gain, and feeding value for cattle fed high concentrate diets were appraised by statistically compiling results from 605 comparisons from feeding trials published in North American journals and experiment station bulletins since 1974. Metabolizable energy (ME) values for each grain and processing method were calculated by quadratic procedures from DMI and animal performance. Averaged across processing methods, ME values for corn, milo, and wheat grain (3.40, 3.22, and 3.46 Mcal/kg DM) fell within 9% of ME estimates from NRC (1996) for beef cattle. In contrast, ME values for barley and oats grain (3.55 and 3.46 Mcal/kg DM) were 24% and 17% greater than NRC (1996) estimates. Compared with the dry rolled forms, high moisture corn and milo resulted in lower ADG and DMI. Compared with dry rolling, either steam rolling or flaking of corn, milo, and wheat decreased DMI without decreasing ADG and improved feed efficiency by 10, 15, and 10%, respectively. Compared with dry rolled grain, steam flaking increased (P < .05) body weight-adjusted ME of corn and milo grain by 15 and 21%, respectively; body weight-adjusted ME for whole corn was 9% greater (P < .05) than for rolled corn grain. Steam flaking was surprisingly effective (13%) at increasing (P < .05) the body weight-adjusted ME of wheat, but steam flaking failed to increase the ME of barley and oats. Higher moisture content of high-moisture corn decreased dry matter intake without depressing ADG and improved efficiency and increased ME of the grain. Compared with steam flakes of moderate thinness, processing milo or barley to a very thin flake tended to reduce ADG and failed to improve feed efficiency. The ideal roughage source and roughage moisture content for maximum ME and ADG varied with grain processing method. Feeding corn silage rather than alfalfa and wet rather than dry roughage depressed (P < .01) ADG of cattle and reduced (P < .01) body weight-adjusted ME of cattle fed high-moisture corn grain but tended to increase both with steam-flaked corn or wheat.
Rat Prefrontal Cortical Neurons Selectively Code Strategy Switches

Multiple memory systems are distinguished by different sets of neuronal circuits and operating principles optimized to solve different problems across mammalian species (Tulving and Schacter, 1994). When a rat selects an arm in a plus maze, for example, the choice can be guided by distinct neural systems (White and Wise, 1999) that encode different relationships among perceived stimuli, actions, and reward. Thus, egocentric or stimulus–response associations require striatal circuits, whereas spatial or episodic learning requires hippocampal circuits (Packard et al., 1989). Although these memory systems function in parallel (Packard and McGaugh, 1996), they can also interact competitively or synergistically (Kim and Ragozzino, 2005). The neuronal mechanisms that coordinate these multiple memory systems are not fully known, but converging evidence suggests that the prefrontal cortex (PFC) is central. The PFC is crucial for abstract, rule-guided behavior in primates and for switching rapidly between memory strategies in rats. We now report that rat medial PFC neuronal activity predicts switching between hippocampus- and caudate-dependent memory strategies. Prelimbic (PL) and infralimbic (IL) neuronal activity changed as rats switched memory strategies even as the rats performed identical behaviors but did not change when rats learned new contingencies using the same strategy. PL dynamics anticipated learning performance whereas IL lagged, suggesting that the two regions help initiate and establish new strategies, respectively. These neuronal dynamics suggest that the PFC contributes to the coordination of memory strategies by integrating the predictive relationships among stimuli, actions, and reward.
Vertex-Centric Graph Processing: Good, Bad, and the Ugly

We study distributed graph algorithms that adopt an iterati ve vertexcentric framework for graph processing, popularized by Goo gle’s Pregel system. Since then, there are several attempts to imp lement many graph algorithms in a vertex-centric framework, a s well as efforts to design optimization techniques for improving the efficiency. However, to the best of our knowledge, there has not been any systematic study to compare these vertex-centric i mplementations with their sequential counterparts. Our paper a dd esses this gap in two ways. (1) We analyze the computational complexity of such implementations with the notion of time-pro cessor product, and benchmark several vertex-centric graph algor ithms whether they perform more work with respect to their best-kn ow sequential solutions. (2) Employing the concept of balance d practical Pregel algorithms, we study if these implementations suffer from imbalanced workload and large number of iterations. Ou r findings illustrate that with the exception of Euler tour tre e algorithm, all other algorithms either perform asymptotically more work than their best-known sequential approach, or suffer from i mbalanced workload/ large number of iterations, or even both. We also emphasize on graph algorithms that are fundamentally diffic ult to be expressed in vertex-centric frameworks, and conclude by discussing the road ahead for distributed graph processing.
Localizing antipodal grasps in point clouds

This paper proposes a new approach to detecting grasp points on novel objects presented in clutter. The input to our algorithm is a point cloud and the geometric parameters of the robot hand. The output is a set of hand configurations that are expected to be good grasps. Our key idea is to use knowledge of the geometry of a good grasp to improve detection. First, we use a geometrically necessary condition to sample a large set of high quality grasp hypotheses. We were surprised to find that using simple geometric conditions for detection can result in a relatively high grasp success rate. Second, we use the notion of an antipodal grasp (a standard characterization of a good two fingered grasp) to help us classify these grasp hypotheses. In particular, we generate a large automatically labeled training set that gives us high classification accuracy. Overall, our method achieves an average grasp success rate of 88% when grasping novels objects presented in isolation and an average success rate of 73% when grasping novel objects presented in dense clutter. This system is available as a ROS package at http://wiki.ros. org/agile_grasp.
Mineralization of the Deep Gray Matter with Age: A Retrospective Review with Susceptibility-Weighted MR Imaging

BACKGROUND AND PURPOSE: Susceptibility-weighted imaging (SWI) is an advanced MR imaging sequence that can be implemented at high resolution. This sequence can be performed on conventional MR imaging scanners and is very sensitive to mineralization. The purpose of this study was to establish the course of mineralization in the deep gray matter with age by using SWI. Materials and METHODS: We retrospectively reviewed susceptibility-weighted images of 134 patients (age range, 1 to 88 years). Inclusion criteria comprised a normal conventional MR imaging (T1, T2, and fluid-attenuated inversion recovery sequences). We statistically analyzed the relative signal intensities of the globus pallidus, putamen, substantia nigra, caudate nucleus, red nucleus, and thalamus for correlation with age. The putamen was graded according to a modified scale, based on previous work that described a systematic pattern of mineralization with age. Bands of hypointensity in the globus pallidus, dubbed “waves,” were also evaluated. RESULTS: We documented decreasing intensity (ie, increasing mineralization) with age in all deep gray matter areas analyzed. We confirmed the age-related posterolateral to anteromedial progression of mineralization in the putamen. Characteristic medial and lateral bands of mineralization were exhibited in the globus pallidus in all children and young adults older than 3 years. Finally, an increase in the number of “waves” present in the globus pallidus was associated with increased age by category. CONCLUSION: This study documents the course and pattern of mineralization in the deep gray matter with age, as determined by SWI. These findings may play a role in evaluating diseased brains in the future.
Different nerve-gliding exercises induce different magnitudes of median nerve longitudinal excursion: an in vivo study using dynamic ultrasound imaging.

STUDY DESIGN Controlled laboratory study using single-group, within-subject comparisons. OBJECTIVES To determine in an in vivo study whether different types of nerve-gliding exercises are associated with different amounts of longitudinal nerve excursion. BACKGROUND Different types of nerve-gliding exercises have been proposed. It is assumed that different exercises produce different amounts of excursion and strain in the peripheral nervous system. Although this has been confirmed in cadaveric experiments, in vivo studies are lacking. METHODS High-resolution ultrasound was used to measure longitudinal excursion of the median nerve in the upper arm during 6 different nerve-gliding exercises. Nerve mobilization techniques that involved the elbow and neck were evaluated in 15 asymptomatic volunteers (mean +/- SD age, 30 +/- 8 years). Nerve longitudinal excursion was calculated using a frame-by-frame cross-correlation analysis. A repeated-measures analysis of variance was used to analyze the data. RESULTS Different exercises induced different amounts of longitudinal nerve excursion (P<.0001). The "sliding technique" was associated with the largest excursion (mean +/- SD, 10.2 +/- 2.8 mm; P = .0001). The amount of nerve movement associated with the "tensioning technique" (mean +/- SD, 1.8 +/- 4.0 mm) was smaller than the nerve excursion induced with individual movements of the neck or elbow (mean +/- SD range, -3.4 +/- 0.9 to 5.6 +/- 2.1 mm; P = .0001). CONCLUSION These findings confirm that different types of neurodynamic techniques have different mechanical effects on the nervous system. Recognition of these differences may assist in the selection of treatment techniques. Having demonstrated differences in mechanical effects, future research will have to evaluate whether these different techniques are also associated with different physiological and therapeutic effects.
Characterization of sea cucumber (stichopus japonicus) ovum hydrolysates: calcium chelation, solubility and absorption into intestinal epithelial cells.

BACKGROUND Sea cucumber (Stichopus japonicus) ovum hydrolysates (SCOHs) chelated with calcium were produced to investigate the characteristics of calcium binding and solubility, as well as to study any effects on calcium absorption by human intestinal epithelial cells. RESULTS The results of the present study show that the calcium-binding capacity of SCOHs depended greatly on the type of proteases. The maximum level of Ca binding (0.38 mmol L-1 ) occurred when trypsin was used, with a peptide yield of 85.7%. Investigation of the possible chelating modes between SCOHs and calcium ions indicated that calcium ions bound to SCOHs primarily via interactions with carboxyl oxygen and amino nitrogen atoms of Glu and Asp and also that the phosphoserine residues might be also responsible for SCOH-calcium chelation. Moreover, SCOH-calcium complexes maintained the solubility of calcium under simulated gastrointestinal digestion, regardless of the presence of dietary components such as oxalate. Furthermore, SCOH-Ca led to higher peak intracellular [Ca2+ ]i in both Caco-2 cells (338.3 nmol L-1 versus 269.6 nmol L-1 ) and HT-29 cells (373.9 nmol L-1 versus 271.7 nmol L-1 ) than casein phosphopeptide-Ca. CONCLUSION Carboxyl oxygen and amino nitrogen atoms in the SCOHs could bind calcium ions, forming SCOH-calcium complexes. These complexes improved calcium solubility under simulated gastrointestinal digestion and also promoted calcium absorption in Caco-2 and HT-29 cells. © 2017 Society of Chemical Industry.
A Systematic Approach for Dynamic Security Assessment and the Corresponding Preventive Control Scheme Based on Decision Trees

This paper proposes a decision tree (DT)-based systematic approach for cooperative online power system dynamic security assessment (DSA) and preventive control. This approach adopts a new methodology that trains two contingency-oriented DTs on a daily basis by the databases generated from power system simulations. Fed with real-time wide-area measurements, one DT of measurable variables is employed for online DSA to identify potential security issues, and the other DT of controllable variables provides online decision support on preventive control strategies against those issues. A cost-effective algorithm is adopted in this proposed approach to optimize the trajectory of preventive control. The paper also proposes an importance sampling algorithm on database preparation for efficient DT training for power systems with high penetration of wind power and distributed generation. The performance of the approach is demonstrated on a 400-bus, 200-line operational model of western Danish power system.
Reduction of the blind spot in the time-frequency domain reflectometry

In this paper, we propose a method to reduce the blind spot based on signal processing that indicates the minimum length of a cable under test in the time-frequency domain reflectometry without using an extension cable or adding a new high-speed hardware component. The time-frequency domain reflectometry adopted the proposed method can be achieved with not only a simple modification of the previous system but also a simple technique based on signal processing. The experimental results show that the proposed method allows us to estimate fault distance on the cable with high spatial resolution.
Intestinal Ciprofloxacin Efflux: The Role of Breast Cancer Resistance Protein (ABCG2)

Intestinal secretory movement of the fluoroquinolone antibiotic, ciprofloxacin, may limit its oral bioavailability. Active ATP-binding cassette (ABC) transporters such as breast cancer resistance protein (BCRP) have been implicated in ciprofloxacin transport. The aim of this study was to test the hypothesis that BCRP alone mediates intestinal ciprofloxacin secretion. The involvement of ABC transport proteins in ciprofloxacin secretory flux was investigated with the combined use of transfected cell lines [bcrp1/BCRP-Madin-Darby canine kidney II (MDCKII) and multidrug resistance-related protein 4 (MRP4)-human embryonic kidney (HEK) 293] and human intestinal Caco-2 cells, combined with pharmacological inhibition using 3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6, 7,12,12a-octahydropyrazino[1′,2′:1,6]pyrido[3,4-b]indol-3-yl)-propionic acid tert-butyl ester (Ko143), cyclosporine, 3-[[3-[2-(7-chloroquinolin-2-yl)vinyl]phenyl]-(2-dimethylcarbamoylethylsulfanyl)methylsulfanyl] propionic acid (MK571), and verapamil as ABC-selective inhibitors. In addition, the regional variation in secretory capacity was investigated using male Han Wistar rat intestine mounted in Ussing chambers, and the first indicative measurements of ciprofloxacin transport by ex vivo human jejunum were made. Active, Ko143-sensitive ciprofloxacin secretion was observed in bcrp1-MDCKII cell layers, but in low-passage (BCRP-expressing) Caco-2 cell layers only a 54% fraction was Ko143-sensitive. Ciprofloxacin accumulation was lower in MRP4-HEK293 cells than in the parent line, indicating that ciprofloxacin is also a substrate for this transporter. Ciprofloxacin secretion by Caco-2 cell layers was not inhibited by MK571. Secretory flux showed marked regional variability in the rat intestine, increasing from the duodenum to peak in the ileum. Ciprofloxacin secretion was present in human jejunum and was reduced by Ko143 but showed marked interindividual variability. Ciprofloxacin is a substrate for human and rodent BCRP. An additional pathway for ciprofloxacin secretion exists in Caco-2 cells, which is unlikely to be MRP(4)-mediated. BCRP is likely to be the dominant transport mechanism for ciprofloxacin efflux in both rat and human jejunum.
Analogies and Differences between Mutation Operators for WS-BPEL 2.0 and Other Languages

Applying mutation testing to a program written in a certain language requires that a set of mutation operators is defined for that language. The mutation operators need to adequately cover the features of that language in order to be effective. In this work, we evaluate qualitatively the operators defined for the Web Services Business Process Execution Language 2.0 (WS-BPEL) and study the differences and similarities between WS-BPEL and other languages. We review the existing operators for several structured and object-oriented general-purpose programming languages, and for several domain-specific languages. Results confirm that WS-BPEL is very different from other languages, as half of the mutation operators for this language are equivalent to those of other languages. Our study concludes that the set of WS-BPEL mutation operators can be improved.
Trace selection for improved WLAN monitoring

Existing measurement techniques for IEEE~802.11-based networks assume that the higher the density of monitors in the target area, the higher the quality of the measure. This assumption is, however, too strict if we consider the cost involved in monitor installation and the necessary time to collect and merge all traces. In this paper, we investigate the balance between number of traces and completeness of collected data. We propose a method based on similarity to rank collected traces according to their contribution to the monitoring system. With this method, we are able to select only a subset of traces and still keep the quality of the measure, while improving system scalability. In addition, based on the same rank, we identify monitors that can be relocated to enlarge the monitored area and increase the overall efficiency of the system. Finally, our experimental results show that the proposed solution leads to a better tradeoff in terms of unique captured frames over the number of merge operations.
Synergistic effect of bladder cancer-specific oncolytic adenovirus in combination with chemotherapy

Gene therapy with adenoviral early region gene (E1A) may enhance the susceptibility of neoplastic cells to chemotherapy-induced cell death. Our previous study developed a urothelium-specific oncolytic serotype 5 adenovirus (Ad5) with the uroplakin II (UPII) promoter controlling E1A expression. The present study investigated whether this urothelium-specific recombinant adenovirus (Ad5-UPII-E1A) enhanced mitomycin (MMC) and hydroxycamptothecin (HCPT) sensitization and drug-induced apoptosis in bladder cancer cells. The results of the MTT assay revealed that combination therapy, using Ad5-UPII-E1A and MMC or HCPT, synergistically inhibited the viability of bladder cancer cells in a dose- and time-dependent manner when compared with either agent alone. When cells were treated with Ad5-UPII-E1A alone they arrested in the G1 phase, but cell cycle analysis by flow cytometry revealed S phase arrest when treated with combined therapy. Treatment with MMC or HCPT enhanced Ad5-UPII-E1A-induced apoptosis in 5,637 cells, observed by transmission electron microscopy. Western blot analysis revealed that MMC and HCPT enhanced the E1A expression of the Ad5-UPII-E1A vectorin a dose-dependent manner. The present study demonstrated that Ad5-UPII-E1A combined with MMC or HCPT resulted in synergistic cytotoxicity in a process which involved the promotion of apoptosis in bladder cancer cell lines. MMC and HCPT also promoted the oncolytic effect of Ad5-UPII-E1A. Thus, treatment using Ad5-UPII-E1A combined with MMC or HCPT may be an attractive strategy for the sensitization of bladder cancer to chemotherapy.
Developmental dyscalculia: a prospective six‐year follow‐up

To determine the natural history of developmental dyscalculia (DC) and factors impacting on its prognosis, we performed a prospective six‐year longitudinal study. One hundred and forty children of normal intelligence diagnosed with DC in the fifth grade of elementary school were re‐examined for dyscalculia three and six years later, in eighth (n=123) and eleventh (n=104; 41 males, 63 females) grades respectively. Mean age of the children in fifth grade was 11 years 1 month (SD 4 months), in eighth grade 14 years 2 months (SD 1 month), and in eleventh grade 17 years 2 months (SD 5 months). The assessment included standardized arithmetic, reading and writing tests, behavioural rating scales, information on socioeconomic status, educational interventions, and familial learning problems. Participants in eleventh grade were recategorized as having DC if their score on the arithmetic test was not more than the fifth centile for grade. At the six‐year follow‐up, 99/104 (95%) children diagnosed with dyscalculia in fifth grade were still performing poorly in arithmetic, scoring within the lowest quartile for their grade, and 42/104 (40%) were recategorized with DC. Chronicity of DC was associated with severity of the dyscalculia in fifth grade (p<0.05), lower IQ (p<0.01), inattention (p<0.01), and writing problems (p<0.01). Thus, DC is an enduring specific learning difficulty,* persisting into late adolescence in almost half of affected individuals.
tritional status and socioeconomic change among Toba and Wichı́ pulations of the Argentinean Chaco udia

The prevalence of overweight and obesity is growing at an accelerated pace in disadvantaged populations. Indigenous populations all over the world, whose lifestyle is changing rapidly and drastically, seem to be particularly prone to show an increased prevalence of overweight and its co-morbidities among adults. The aim of this study was to evaluate the association between socioeconomic and nutritional statuses in adults of two indigenous populations of the Argentine Gran Chaco: the Toba and Wichı́ of the province of Formosa. Originally hunter–gatherers, they are now more settled and engage in temporary wage labor and local political positions. A total of 541 adults (>20 years old) participated in the study. Almost 50% of the adult Toba and 34% of the adult Wichı́ were overweight and 10% of adults in both populations were obese. Socioeconomic status was positively associated with body mass index in both populations. Furthermore, political connectedness with the non-indigenous sector, as in the case of community leaders, was highly correlated with obesity. Differences within and between groups can be explained by biocultural factors that include gender, diet (foraged vs store-bought), lifestyle (sedentary vs more active), and history of political power. Our study highlights the interactions among social, cultural, and political economic variables, such as political hierarchies within the group or degree of social connectedness with community leaders. By making these variables an integral part of our analysis and interpretation, we hope to improve our understanding of the situation of indigenous populations in transition. 2009 Elsevier B.V. All rights reserved. Corresponding author at: Department of Anthropology, University of nsylvania, 325 University Museum, 3260 South St., Philadelphia, PA 96, USA. Tel. : +1 215 746 5162; fax: +1 215 898 7462. E-mail addresses: valeggia@sas.upenn. edu, eduardof@sas.upenn. edu . Valeggia), burkevin@sas.upenn. edu (K.M. Burke).