Miracle-dz/UniFAR-FTUs huggingface dataset:
Quality Management Systems and Information Systems: Getting More than the Sum of the Parts

Companies are increasingly concerned with quality management of their products and services. Holding a quality certification, such as ISO 9001:2000, is becoming a compulsory requirement to play in selected markets. Designing a quality management system requires the extensive involvement of staff and managers and the analysis and redesign of business procedures. Interestingly enough, very similar requisites and tasks characterize enterprise systems design. However, the two endeavors are systematically conducted as separate projects, which are handled by different teams, equipped with unconnected methodologies. We present the first results of an approach we are developing to simultaneousl y address the design of the Quality Management System and of the Enterprise System. We identify the important synergies between the two initiatives, with the ultimate goal of creating a streamlined match between business processes and information system support, so that, when the project is finished, we can get both a fully operational information system and an officially certified quality audit for the whole enterprise.
Unique Human Tumor Antigens: Immunobiology and Use in Clinical Trials1

The individual, unique tumor Ags, which characterize each single tumor, were described 50 years ago in rodents but their molecular characterization was limited to few of them and obtained during the last 20 years. Here we summarize the evidence for the existence and the biological role of such Ags in human tumors, although such evidence was provided only during the last 10 years and by a limited number of studies, a fact leading to a misrepresentation of unique Ags in human tumor immunology. This was also due to the increasing knowledge on the shared, self-human tumor Ags, which have been extensively used as cancer vaccines. In this review, we highlight the biological and clinical importance of unique Ags and suggest how they could be used in clinical studies aimed at assessing their immunogenic and clinical potential both in active and adoptive immunotherapy of human tumors.
A Reference-Free Capacitive-Discharging Oscillator Architecture Consuming 44.4 pW/75.6 nW at 2.8 Hz/6.4 kHz

This paper presents a capacitive-discharging oscillator architecture that achieves ultra-low-power operation without a temperature-stabilized reference generator by directly relying on the RC time constants of capacitors discharging across passively-temperature-stabilized resistive elements. The architecture operates by pre-charging two capacitors to the supply voltage, and then discharging one of the capacitors through a resistive path, while the other capacitor charge-shares with a third capacitor in order to generate a reference potential for comparison to flip phases. The architecture is demonstrated with two fully-integrated implementations in two different process technologies: 250 nm and 65 nm. The 250 nm implementation employs poly resistors, operates at 6.4 kHz, consumes 75.6 nW, and achieves a temperature stability of 0.74% (148 ppm/°C) from 20°C to 80°C when measured over five samples. The 65 nm implementation employs gate-leakage resistors, operates at 2.8 Hz, consumes 44.4 pW, and achieves a temperature stability of 1260 ppm/°C across a temperature range of -40°C to 60°C over five samples. The two implementations demonstrate low-cost, low-power, and stable timing solutions at Hz-to-kHz-range frequencies for next-generation Internet-of-Things sensors.
FREEZING INJURY OF MAIZE SEED.

Maturity of the crop is the primary factor determining the damage done by frost. Freezing temperatures kill the foliage and stalk of immature plants, thus stopping translocation to the partially developed grain. The grain itself may be damaged with lowered keeping qualities and viability. Injury is especially serious to the hybrid seed corn industry where expensively produced seed may be reduced to low grade feed. Freezing injury to plants has been divided into sudden killing by intracellular crystal formation, and slow desiccation and precipitation of the protoplasm when moisture is withdrawn by intercellular ice formation. Levitt (3) and Luyet and Gehenio (5) have published extensive reviews of the theories of cold injury. Kiesselbach and Ratcliff (2) conducted a study of freezing injury to open-pollinated seed corn from 1913 to 1920, but open-pollinated varieties have been replaced by hybrid corn for which there are few data on frost injury. The present study was undertaken to determine the effects of temperature, moisture content of the seed, length of freezing period, variety of seed, physiological maturity, rate of freezing and thawing, repeated freezing and thawing, and rate of drying on freezing damage to hybrid maize seed. Yields of corn grown from frozen and unfrozen seed were compared. Materials and Methods Experiments with soaked seed
Relatos y literatura de viajes en el ámbito hispánico: poética e historia

Se interroga Beatriz Colombi en Viaje intelectual. Migraciones y desplazamientos en América Latina (1880-1915): «¿De qué hablamos cuando se habla de literatura de viajes? ». Su pregunta tiene sentido, puesto que «no se trata tan sólo de un antiquísimo género literario o discursivo, de un copioso imaginario privilegiado y alimentado por la ficción o de una práctica ligada a la ciencia y a la expansión territorial de Occidente. Su alcance encubre un universo al que sólo podemos aludir como cultura: la cultura del viaje, cuyo estudio admite un haz de perspectivas heterogéneas» (Rosario: Beatriz Viterbo, 2004: 13). La cita de Colombi sitúa la literatura de viajes en un escenario plural, donde se cruzan géneros, imaginarios, ideologías y temáticas múltiples, que convierten esta tendencia literaria en un campo fascinante, pero que reviste notable complejidad.
Wireless transmission of JPEG 2000 compressed video

In this paper, we propose a wireless transmission of JPEG 2000 compressed video. The proposed system employs the next generation wireless LAN system based on IEEE802.11ac specification. It reaches more than 33 meter propagation distance by using 80MHz of bandwidth on the 5GHz band. In this system, video data is compressed by JPEG 2000 with error resilience tools. These tools improve error performance against wireless channel, and enable very high throughput communication. Computer simulations are used to evaluate the bit error performance's influences to the video quality. Finally, we present RTL design results of the proposed wireless LAN system.
CFD simulation of flow characteristics of pumpjet propulsor

In this study, numerical investigations of flow characteristics of a pumpjet propulsor based on Computational Fluid Dynamics (CFD) method have been presented. The Zwart-Gerber-Belamri (Z-G-B) cavitation model based on the Reynolds Averaged Navier-Stokes (RANS) method is employed. The structured gird is applied. A four-blade skewed E779A propeller has been used to verify the numerical method. The comparison of the pressure contour under the condition of non-cavitating and cavitating flows at different axial position has been presented. The formation and development of the tip clearance flows has been investigated and presented. The structure of the tip leakage vortex has been shown. Furthermore, the radial distributions of different velocity components with different span along the axial direction have been carried out to present the influence of the tip clearance flow on the main flow.
An Automatic Multi-sample 3D Face Registration Method Based on Thin Plate Spline and Deformable Model

Non-rigid registration of 3D facial surfaces is a crucial step in a variety of computer vision tasks. In this paper, we present a fully automatic 3D face registration method based on the thin plate spline (TPS) and deformable model. To model the non-rigid modality of complex 3D facial surfaces, the thin plate spline is adopted to represent the transformation between 3D faces. The farthest point sampling (FPS) method is used to generate the control points for the thin plate spline transformation automatically. There are two phases for 3D face registration. Firstly, the preliminary registration is obtained by closest points searching between the thin plate spline transformed reference and the target. Then the multi-sample registration is implemented to improve the precision of the registration by using a dynamical reference produced based on deformable model. To eliminate outliers countermeasures are presented in both phases. The experiments on Bu-3dfe and Bjut-3d face databases show that the proposed method is effective and robust.
Enzymatic synthesis of 2′-ara and 2′-deoxy analogues of c-di-GMP

The substrate specificity of recombinant full-length diguanylate cyclase (DGC) of Thermotoga maritima with mutant allosteric site was investigated. It has been originally shown that the enzyme could use GTP closest analogues – 2′-deoxyguanosine-5′-triphosphate (dGTP) and 9-β-D-arabinofuranosyl-guanine-5′-triphosphate (araGTP) as the substrates. The first demonstrations of an enzymatic synthesis of bis-(3′-5′)-cyclic dimeric deoxyguanosine monophosphate (c-di-dGMP) and the previously unknown bis-(3′-5′)-cyclic dimeric araguanosine monophosphate (c-di-araGMP) using DGC of T. maritima in the form of inclusion bodies have been provided.
A linkage tournament: affection status, parametric analysis, multivariate traits, and enhancements to variance components and relative pairs

Linkage tests to localize oligogenes have been extended during the past year. Using simulated data and multiplex selection we find that several tests on affected sib pairs have comparable power and type I error. Three variants of SIBPAL2 are favoured when substantial numbers of normal sibs are included, but performance relative to the BETA benchmark degrades rapidly as normal sibs are depleted by selective sampling or typing. Neglect of this fact may explain recent failure of retrospective collaboration to confirm asthma candidates in the 5q cytokine region that are supported by other studies. A fully quantitative trait favours variance components under complete ascertainment and two options in SIBPAL2 under multiplex selection, with substantial gain in power from covariance analysis if the covariate is independent of the candidate locus. A dichotomy and liability threshold give virtually identical results in the SOLAR variance components program. Comparison with single‐marker parametric analysis suggests that extension to multiple markers would be competitive with nonparametric methods in power, and superior in depth of genetic analysis. The simulated examples illustrate common problems encountered with linkage scans for oligogenes. They show that nonparametric methods provide no panacea for analytical problems posed by different phenotypes and methods of ascertainment.
Spinal and trigeminal dorsal horn projections to the parabrachial nucleus in the rat

We studied afferents to the parabrachial nucleus (PB) from the spinal cord and the spinal trigeminal nucleus pars caudalis (SNVc) in the rat by using the anterograde and retrograde transport of wheat germ agglutinin conjugated to horseradish peroxidase (WGA‐HRP). Injections of WGA‐HRP into medial PB retrogradely labeled neurons in the promontorium and in lamina I of the dorsal rostral SNVc, while injections into lateral PB and the Kölliker‐Fuse nucleus retrogradely labeled neurons in these areas as well as in lamina I throughout the caudal SNVc and spinal dorsal horn. Injections of WGA‐HRP into the caudal SNVc and dorsal horn of the spinal cord resulted in terminal labeling in the dorsal, central, and external lateral subnuclei of PB and the Kölliker‐Fuse nucleus, all of which are known to receive cardiovascular and respiratory afferent information. Injections of WGA‐HRP into the promontorium and dorsal rostral SNVc resulted in terminal labeling in the same PB subnuclei, as well as in the medial and the ventral lateral PB subnuclei, which are sites of relay for gustatory information ascending from the medulla to the forebrain. The spinal and trigeminal projection to PB may mediate the convergence of pain, chemosensory, and temperature sensibilities with gustatory and cardiorespiratory systems in PB.
Activating Ly-49 NK Receptors: Central Role in Cytokine and Chemokine Production

In an attempt to understand potential novel functions of receptors in vivo, we evaluated gene expression after cross-linking the activating Ly-49D mouse NK receptor. Gene expression was evaluated using a mouse GEM 2 microarray chip (Incyte Genomics, St. Louis, MO). Each chip displays a total of 8734 elements. The strongly induced genes fell into two categories: 1) soluble factors and 2) apoptotic genes. The majority of the strongly induced mRNAs as analyzed by microarray hybridization were chemokine genes. RNase protection assays and chemokine protein production analysis validated the microarray results, as cross-linking the Ly-49D mouse NK receptor induced high levels of IFN-γ, lymphotactin, macrophage-inflammatory protein (MIP)1α, and MIP1β. This gene expression was specific because other chemokines were not induced by anti-Ly-49D receptors. In addition, a series of pharmacological inhibitors were used to identify the key signaling pathways involved in the cellular response. The primary Ly-49D signaling for IFN-γ production is predominately mediated through Src kinase pathways involving membrane proximal events, whereas MIP1α and MIP1β gene induction is more complex and may involve multiple biochemical pathways. Thus, we conclude that a primary role for the activating NK receptors in vivo may be to trigger soluble factor production and regulation of the immune response. This would place NK cells and their activating Ly-49 receptors as important initiators of microbial immunity and key elements of the innate immune system.
Premiers test et validation de la transposition d'une échelle de personnalité humaine aux marques

Cet article a pour objectif de tester la transposition d'une échelle de personnalité humaine (Saucier, 1994) sur les marques au moyen d'une analyse factorielle confirmatoire. Notre étude s'appuie sur un échantillon de convenance de 537 étudiants et traite de seize marques achetées dans un contexte français. Une analyse de congruence entre les deux échelles de personnalité montre leur équivalence structurelle; une analyse en composantes principales non linéaires sur les associations entre les traits de personnalité humains et ceux de la marque établit leur équivalence sémantique. Enfin, une analyse canonique généralisée non linéaire permet d'apprécier la validité prédictive de la personnalité du consommateur et celle de la marque.
Interleukin‐10 and regeneration in an end‐to‐side nerve repair model of the rat

End‐to‐side (ETS) neurorrhaphy is an option in peripheral nerve surgery. The aim of this study was to investigate whether the application of the anti‐inflammatory cytokine interleukin‐10 (IL‐10) reduces scarring and thus enhances nerve regeneration in an ETS peroneal/tibial nerve lesion model of the rat. Twenty rats with a peroneal to tibial ETS neurorrhaphy were divided into two groups: (1) control group and (2) IL‐10 group with intrafascicular application of 0.125 µg/100 µl IL‐10. Survival time was 8 weeks. Nerve conduction velocities (NCVs) and motor function were analyzed and histomorphological evaluation with measurement of intraneural collagen level, axon count, total nerve area, and myelination index followed. Evaluation of motor function and nerve conduction did not show any statistical differences. Histological analyses revealed thicker myelin sheaths and higher myelination index in the IL‐10 group (p < 0.001). Axon count showed no difference. The IL‐10 group revealed lower collagen levels (p < 0.001). Comparison of total nerve area showed no statistical significance. At this dose, IL‐10 evaluated at 8 weeks was not significantly different than placebo in functional, NCVs, and most morphological measures. However, there was a significant difference in thicker myelin sheaths and higher myelination index and lower collagen levels. This suggests that future experiments of IL‐10 at different doses or longer periods of evaluation would be of interest.
Stereo Visual SLAM for Mobile Robots Navigation

Esta tesis esta enfocada a la combinacion de los campos de la robotica movil y la vision por computador, con el objetivo de desarrollar metodos que permitan a un robot movil localizarse dentro de su entorno mientras construye un mapa del mismo, utilizando como unica entrada un conjunto de imagenes. Este problema se denomina SLAM visual (por las siglas en ingles de "Simultaneous Localization And Mapping") y es un tema que aun continua abierto a pesar del gran esfuerzo investigador realizado en los ultimos anos. En concreto, en esta tesis utilizamos camaras estereo para capturar, simultaneamente, dos imagenes desde posiciones ligeramente diferentes, proporcionando asi informacion 3D de forma directa. De entre los problemas de localizacion de robots, en esta tesis abordamos dos de ellos: el seguimiento de robots y la localizacion y mapeado simultaneo (o SLAM). El primero de ellos no tiene en cuenta el mapa del entorno sino que calcula la trayectoria del robot mediante la composicion incremental de las estimaciones de su movimiento entre instantes de tiempo consecutivos. Cuando se usan imagenes para calcular esta trayectoria, el problema toma el nombre de "odometria visual", y su resolucion es mas sencilla que la del SLAM visual. De hecho, a menudo se integra como parte de un sistema de SLAM completo. Esta tesis contribuye con la propuesta de dos sistemas de odometria visual. Uno de ellos esta basado en un solucion cerrada y eficiente mientras que el otro esta basado en un proceso de optimizacion no-lineal que implementa un nuevo metodo de deteccion y eliminacion rapida de espurios. Los metodos de SLAM, por su parte, tambien abordan la construccion de un mapa del entorno con el objetivo de mejorar sensiblemente la localizacion del robot, evitando de esta forma la acumulacion de error en la que incurre la odometria visual. Ademas, el mapa construido puede ser empleado para hacer frente a situaciones exigentes como la recuperacion de la localizacion tras la perdida del robot o realizar localizacion global. En esta tesis se presentan dos sistemas completos de SLAM visual. Uno de ellos se ha implementado dentro del marco de los filtros probabilisticos no parametricos, mientras que el otro esta basado en un metodo nuevo de "bundle adjustment" relativo que ha sido integrado con algunas tecnicas recientes de vision por computador. Otra contribucion de esta tesis es la publicacion de dos colecciones de datos que contienen imagenes estereo capturadas en entornos urbanos sin modificar, asi como una estimacion del camino real del robot basada en GPS (denominada "ground truth"). Estas colecciones sirven como banco de pruebas para validar metodos de odometria y SLAM visual.
Design of Novel Shaftless Pump-Jet Propulsor for Multi-Purpose Long-Range and High-Speed Autonomous Underwater Vehicle

Owning to its extremely long endurance, small size, cost-effective employment, easy, and fast transported properties, the merits of autonomous underwater vehicles (AUVs) exceed those of manned underwater vehicles. Therefore, it has become an indispensable member in navies throughout the world, as well as with oceanographic research, commercial resource explorations, and especially the underwater search and rescue (SAR) sectors. Up to date, the tragic MH370 and QZ8501 flight incidents have dramatically increasing the awareness of high-performance SAR equipment, which in turn will stimulate the states party to the incident to urgently upgrade their shallow- and deep-sea SAR equipment. To extend the range (endurance) and shorter the searching period for the next generation SAR AUV, a sea water cooled high-power density magnetically slotless permanent magnet brushless motor is proposed and integrated with pump-jet's impeller to achieve designated shaftless pump-jet propulsor. In this paper, the developed shaftless pump-jet propulsion system is applied in Naval University of Engineering series multi-purpose long-range and high-speed deep-sea AUV, which could provide excellent performance as a SAR platform.
Relocalization of the Mre11-Rad50-Nbs1 Complex by the Adenovirus E4 ORF3 Protein Is Required for Viral Replication

ABSTRACT Adenovirus replication is controlled by the relocalization or modification of nuclear protein complexes, including promyelocytic leukemia protein (PML) nuclear domains and the Mre11-Rad50-Nbs1 (MRN) DNA damage machinery. In this study, we demonstrated that the E4 ORF3 protein effects the relocalization of both PML and MRN proteins to similar structures within the nucleus at early times after infection. These proteins colocalize with E4 ORF3. Through the analysis of specific viral mutants, we found a direct correlation between MRN reorganization at early times after infection and the establishment of viral DNA replication domains. Further, the reorganization of MRN components may be uncoupled from the ability of E4 ORF3 to rearrange PML. At later stages of infection, components of the MRN complex disperse within the nucleus, Nbs1 is found within viral replication centers, Rad50 remains localized with E4 ORF3, and Mre11 is degraded. The importance of viral regulation of the MRN complex is underscored by the complementation of E4 mutant viruses in cells that lack Mre11 or Nbs1 activity. These results illustrate the importance of nuclear organization in virus growth and suggest that E4 ORF3 regulates activities in both PML nuclear bodies and the MRN complex to stimulate the viral replication program.
IMOVINSKI KRIMINALITET U BOSNI I HERCEGOVINI PREMA ZVANIČNIM STATISTIKAMA

Imovina predstavlja jednu od opcezasticenih vrijednosti cije slobodno uživanje je zagarantirano osnovnim pravnim nacelima i normama međunarodnog i nacionalnog prava. Sa historijske tacke gledista, protupravna ponasanja usmjerena otuđenju, ugrožavanju ili ostedenju imovine, imovinskih prava i interesa su oduvijek bila u sredistu pažnje u vecini drustava i kultura. Zbog kontinuiteta njegove zastite, ali i siroke rasprostranjenosti u svim drustvenim zajednicama, imovinski kriminalitet se smatra klasicnim, konvencionalnim oblikom kriminaliteta. Buduci da se radi o masovnoj pojavi, u procesu izucavanja njegovog stanja i kretanja koristi se, pored drugih izvora podataka, zvanicna statistika kriminaliteta, koju se cesto naziva i najpouzdanijim sredstvom saznanja o kriminalitetu. U radu su izloženi podaci o imovinskom kriminalitetu u Bosni i Hercegovini promatrani kroz prizmu tzv. policijskih i pravosudnih statistika te putem apsolutnih i relativiziranih brojki. Nalazi u radu sugeriraju prilicnu konzistentnost imovinskog kriminaliteta u promatranom sedmogodisnjem periodu (2003-2009. godine), te velikom ucescu imovinskog kriminaliteta u ukupno registriranoj masi krivicnih djela. Uz navedeno, vrijedan nalaz rada je, unatoc cestim napisima i izvjescima medija o alarmantnom stanju imovinskog kriminaliteta u Bosni i Hercegovini, da prosjecna stopa za npr. krađe i razbojnistva i razbojnicke krađe u Evropi je 3-4 puta veca nego u nasoj zemlji, a za prevare 10 i vise puta. Iako se ovaj odnos može tumaciti i nekim drugim momentima (naprimjer, drugacijim metodologijama prikupljanja podataka), plauzibilno je za pretpostaviti da stanje u Bosni i Hercegovini sa imovinskim kriminalitetom ipak nije tako lose kakvim se cesto u laickoj javnosti prikazuje. Time se potvrdila u kriminologiji i kriminalistici prilicno rasirena teza o dominaciji imovinskih krivicnih djela u ukupnom kriminalitetu te (vjerovatno) o utjecaju dosta stabilnih makro drustvenih faktora na ukupno stanje kriminaliteta.