Miracle-dz/UniFAR-FTUs huggingface dataset:
Extended left hepatectomy: Technical aspects of an evolving procedure

Lessons learned in an operative experience of 14 patients submitted to extended left hepatectomy for the management of liver tumours are presented. There were no deaths within 30 days of operation. Essential preoperative studies, indications and technical details of the operation are described. The importance of the morphology of the tumour and the influence of the tumour on the technique to be adopted are emphasized. Modifications of technique that allow selection of patients for the procedure, control of venous bleeding, accurate identification of the sectoral portal pedicles within the right liver and definition of the plane of parenchymal transection are addressed.
Effect of horticultural therapy on wellbeing among dementia day care programme participants: A mixed-methods study (Innovative Practice)

Fourteen people attending an adult day programme were recruited to a structured horticultural therapy programme which took place over 10 weeks. The effects were assessed using Dementia Care Mapping and questionnaires completed by family carers. High levels of wellbeing were observed while the participants were engaged in horticultural therapy, and these were sustained once the programme was completed. This study adds to the growing evidence on the benefits of horticultural therapy for people with dementia who have enjoyed gardening in the past.
[DNA typing for HLA-A, B antigens by polymerase chain reaction with sequence-specific primers and clinical application].

OBJECTIVE To establish DNA typing for HLA-A, B antigens in Chinese by polymerase chain reaction with sequence-specific primers (PCR-SSP). METHODS DNA samples were obtained from 178 unrelated donors and 167 kidney recipients. An additional panel of 62 standard DNAs that were typed by UCLA tissue typing lab in USA. A rapid genotyping for HLA-I class (A, B antigens) by PCR-SSP was set up by designed and synthesized 81 specific primers and 1 pair of internal control primer, combining in 61 one-step reactions (20 PCR reactions for A alleles, 41 PCR reactions for B alleles). RESULTS HLA-A, B alleles were successfully typed in 345 clinical samples and 62 standard DNAs by PCR-SSP technique. No false positive or false negative typing results were obtained. Reproducibility was 100% in 40 samples. The overall time of DNA typing was 5 hours. The typing results were consistent with those of UCLA tissue typing lab. Nineteen alleles of HLA-A and 41 HLA-B alleles were accurately distinguished. Thirteen HLA-A alleles and thirty-two HLA-B alleles in Chinese were practically typed. CONCLUSION DNA typing for HLA-I class (A, B antigens) by PCR-SSP has proved to be a technique of high-resolution, high-specificity, well-reproducibility, and more suitable for clinical application than serology.
Inducing Translation Lexicons via Diverse Similarity Measures and Bridge Languages

This paper presents a method for inducing translation lexicons between two distant languages without the need for either parallel bilingual corpora or a direct bilingual seed dictionary. The algorithm successfully combines temporal occurrence similarity across dates in news corpora, wide and local cross-language context similarity, weighted Levenshtein distance, relative frequency and burstiness similarity measures. These similarity measures are integrated with the bridge language concept under a robust method of classifier combination for both the Slavic and Northern Indian language families.
Use of highly specific DNA probes and the polymerase chain reaction to detect Mycobacterium paratuberculosis in Johne's disease

DNA probes that hybridize to a mycobacterial insertion sequence, IS900, present in multiple copies in the genome of Mycobacterium paratuberculosis were found to be highly specific for M. paratuberculosis. DNA sequences derived from IS900 were used to prepare DNA primers for detection and identification of M. paratuberculosis by the polymerase chain reaction. Highly specific direct detection of M. paratuberculosis DNA in feces from cattle with Johne's disease was obtained. The polymerase chain reaction test had a sensitivity equal to or greater than that obtained by standard culture techniques and was much more rapid, taking only hours compared with 6 to 12 weeks for culture.
Matrix Proteases and the Degradome

Proteases are defined as enzymes that have the ability to perform the hydrolysis of peptide bonds. Owing to this characteristic, proteases were initially described as nonspecific enzymes of protein catabolism, participating in processes such as tissue destruction or degradation of dietary proteins. More recently, a better understanding of their functions has allowed consideration of proteases as enzymes that perform highly specific reactions and take part in multiple biological processes such as DNA replication and transcription, cell proliferation, differentiation and migration, tissuemorphogenesis and remodeling, heat shock and unfolded protein responses, neurogenesis, angiogenesis, ovulation, fertilization, wound repair, stem cell mobilization, coagulation, immunity, inflammation, senescence, autophagy, apoptosis, and necrosis [1]. According to the essential roles performed by proteases in all living organisms, alterations in their proteolytic activities may lead to important pathologies such as arthritis, cardiovascular alterations, neurodegenerative disorders, progeroid syndromes, and cancer [2, 3]. The biochemical reaction catalyzed by all proteases consists in the hydrolysis of a peptide bond through the nucleophilic attack at the carbonyl group. However, the way this reaction is performed differs between specific proteases. This characteristic feature has allowed the establishment of six different catalytic classes of proteases according to the group performing the nucleophilic attack: aspartic, metallo, cysteine, serine, and threonine proteases, as well as the most recently described group of glutamic proteases, which has only been found in some species of fungi and bacteria. In the case of aspartic, glutamic, and metalloproteases, a polarized water molecule located in the active center acts directly as a nucleophile, while in the other three classes, the reactive element is a hydroxyl (serine and threonine) or sulfhydryl (cysteine) group from the corresponding catalytic core [4]. Within each class, proteases can be further subdivided into different families and clans according to sequence conservation and three-dimensional structure similarities. The diversity and complexity of proteases have made necessary the introduction of concepts and tools for their global analysis and characterization. Thus, the term
INVESTIGATION OF SWEEP APPLIED TO ROTATING AXIAL CASCADES AND NUMERICAL SIMULATIONS OF FLOW

This paper presents an original approach regarding the application of sweep to rotating blade cascades. The justification for swept blades is given by its consequence, i.e. a reduction of local velocity (usually from supersonic/ transonic to subsonic regimes) such that the losses due to shock waves and/or boundary layer displacement and/or followed by reattachment are minimized. As study cases were considered a cascade blade, as well as forward and backward sweep of span-wise cross sections. The RANS model was used to describe the flow and a comparative study was conducted by using four turbulence models, i.e. Spalart-Allmaras, k-ε, k-ω and Reynolds Stress RST models. The CFD analysis was done with the FLUENT solver, with the settings for 2D case, implicit equations and double precision. The convergence was monitored such that the residuals should be minimized. The results of the numerical simulations of the flow are expressed as the distributions of Mach number (in relative flow, since it is a rotational frame), static pressure, static temperature and entropy, which have been presented comparatively, for each turbulence model and sweep study case, corresponding to the design rotational speed of 275 [m/s].
Binding Site Distribution of Nuclear Transport Receptors and Transport Complexes in Single Nuclear Pore Complexes

Transport through the nuclear pore complex (NPC) involves a large channel and an abundance of binding sites for nuclear transport receptors (NTRs). However, the mechanistically important distribution of NTR‐binding sites along the channel is vividly debated. In this study, we visualized binding site distributions directly by two complementary optical super‐resolution methods, single‐molecule microscopy and 4Pi microscopy. First, we analyzed the distribution of RanGDP because this important nuclear transport substrate has two types of binding sites at the NPC, direct and indirect, NTR‐mediated sites. We found that the direct binding sites had a maximum at approximately −30 nm with regard to the NPC center, whereas the indirect transport‐relevant binding sites peaked at approximately −10 nm. The 20 nm‐shift could be only resolved by 4Pi microscopy because of a two to threefold improved localization precision as compared with single‐molecule microscopy. Then we analyzed the distribution of the NTR Kapβ1 and a Kapβ1‐based transport complex and found them to have also binding maxima at approximately −10 nm. These observations support transport models in which NTR binding sites are distributed all along the transport channel and argue against models in which the cytoplasmic entrance of the channel is surrounded by a large cloud of binding sites.
BRCA1‐related breast cancer in Austrian breast and ovarian cancer families: Specific BRCA1 mutations and pathological characteristics

We identified 17 BRCA1mutations in 86 Austrian breast and ovarian cancer families (20%) that were screened for mutations by denaturing high‐performance liquid chromatography (DHPLC) and the protein<0B> <0R>truncation test (PTT). Eleven distinct mutations were detected, 4 of them (962del4, 2795del4, 3135del4 and L3376stop) not previously reported in families of non‐Austrian origin. In addition, 6 rare missense mutations (allele frequency < 1%) with unknown biological effects were identified. Four mutations occurred more than once in the Austrian population: 2795del4 (3 times), Cys61Gly (3 times) 5382insC (2 times) and Q1806stop (2 times). Haplotype analysis of the 4 recurrent mutations suggested a common ancestor for each of these. Thirty‐four breast cancer cases from 17 families with BRCA1 mutations were further analyzed. We observed a low median age of onset (39.5 years). Sixty‐eight percent of all BRCA1 breast cancer cases had negative axillary lymph nodes. This group showed a significant prevalence of a negative estrogen and progesterone receptor status and stage I tumors compared with an age‐related, node‐negative control group. The prevalence of grade III tumors was marginally significant . Survival analysis either with a control group matched for age (within 5 years), grade, histologic subtype and estrogen receptor status, or with an age‐related, node‐negative comparison group, showed no statistical difference. Int. J. Cancer 77:354–360, 1998. © 1998 Wiley‐Liss, Inc.
Nucleotide sequence and functional analysis of the luxE gene encoding acyl-protein synthetase of the lux operon from Photobacterium leiognathi.

Nucleotide sequence of the luxE gene GenBank Accession No. U66407 from Photobacterium leiognathi PL741 has been determined, and the amino acid sequence of acyl-protein synthetase encoded by the luxE gene is deduced. Nucleotide sequence reveals that the luxE gene encodes acyl-protein synthetase, which is a component of the fatty acid reductase complex that is responsible for converting fatty acid to aldehyde as substrate in the luciferase-catalyzed bioluminescence reaction. The acyl-protein synthetase encoded by the luxE gene has a calculated M, 43,128 and comprises 373 amino acid residues. Alignment and comparison of acyl-protein synthetases from P. leiognathi, P. phosphoreum, Vibrio fischeri, V. harveyi and Xenorhabdus luminescens shows that they are homologous; there is 75.5% homologous (44.2% identity and 31.3% similarity) among these species. Functional analysis illustrates that the specific segment sequence lying before or in the luxE gene might from potential loops omega o omega e1, omega e2 as mRNA stability loop and/or for sub-regulation by alternative modulation in the lux operon. The gene order of the luxE gene in the lux and the lum operons is<--ter-lumQ-lumP-R&R-luxC-luxD-luxA-luxB -luxN-luxE-->(R&R: regulatory region; ter; transcriptional terminator), whereas the R&R is the regulatory region for the lum and the lux operons, and ter is the transcriptional terminator for the lum operon.
Skeletal Muscle

A Skeletal muscle fiber is a large (10-100 m diameter), multinucleated syncytium. Those fibers attached to bone, mediate voluntary movement of the skeleton, and/or maintain body position and posture. Others such as the extra-ocular muscle of the eye and the tongue are not attached to the skeleton but provide precise voluntary movements. Skeletal muscle contraction is controlled by the somatic nervous system.
Administration and Development in Malaysia. Institution Building and Reform in a Plural Society . By Milton J. Esman. Cornell University Press, Ithaca and London. Pp. xiii, 343. Preface, Tables, Diagrams, Bibliography, Index. Price: US$12.50 or £5.95

Combining meticulous scholarly research with a keen eye for the significant, Professor Lebra skilfully weaves her rich collection of personal interviews and Japanese and Indian sources into a story of absorbing interest and value. We are provided with not only an analysis of the larger movements, policies and strategies but also close-ups of the main incidents and the major actors in the drama, especially those on the Japanese side. She takes both the Japanese and Indians seriously and as Professor Benda rightly observes (p. viii), for the first time we begin to get glimpses of "their purposes and actions in the frameworks appropriate to their specific situations and personalities". It will be extremely difficult after this to go back to the stereotypes of the evil and rapacious Japanese or the notions of a well-defined Japanese master-plan for the subjugation of Asia, including India. Unlike the countries of Southeast Asia, India appears to have played only a marginal role in Japanese thinking and wartime plans, for it does not seem to have ever been seriously considered as forming part of the Greater East Asia Co-Prosperity Sphere. Despite the efforts of a few individual Japanese to make the cause of Indian independence that of Japan and Tokyo's ostensible gestures of support and 'recognition' of Azad Hind, the Provisional Government of Free India, at no time did the Imperial Government envisage pushing the borders of Dai Toa much beyond Burma. In this context, while prepared to milk the movement for maximum propaganda value, Japan was willing to grant the form but not the substance of independence to the I.N. A. or the Azad Hind Government. It is possible that some readers will not agree with a few of her interpretations and others may cavil at the poor conceptualization and cartography of her maps and such minor errors as the misplacement of the Perak River of the Malay Peninsula in Kedah. All in all, however, Professor Lebra's book deserves the widest circulation possible and I would like to join the late Professor Harry Benda in saying how much "I have benefited from her account and I hope others will emulate her painstaking research and graceful style".
Aristotelian Logic

If this claim be allowed—and it is difficult to resist it—D assumes major importance, and the primacy of the first family is seriously challenged. Thus it is not surprising that of the 140-odd new manuscript readings adopted more than two-thirds are derived from one or more members of the second family. Some are manifest improvements; a few are unconvincing; of most it may fairly be said that the probabilities are nicely balanced. More interesting are Ross's own emendations—37 in Topics, 54 in Soph. Elench. Many of these will certainly be accepted. Among the most convincing are 133*16 rov . TO for TO . rov, 139*11 prj for ov, i462o TO for TOV, i54i Kwrqyopelrat. added, 170*38 ei re . ei r for eire . eir', I7219 dyei for ayew, i7833 ovSe TO, i822o Kartpvcafievov. Some of the others seem unnecessary. How far an Aristotelian text should be purged of seeming imperfections by emendation will always be debatable, since so much depends upon the view that you take of the autograph; but nobody will deny that Ross has tidied up a great many irregularities—above all the fairly frequent confusion of ort and SIOTI—and has often improved or at least clarified the sense. There are a good many minor errors or misprints, and a few which call for mention, since they may puzzle or mislead. i037 for TI read TO; 106*3 f° dXoyovs read Xoyovs; 106*7 (PPcrit.) for Tread A; 106*8 em omitted before r&v dXXwv; no*6 (app. crit.) citations transposed; 110*29 P°s T0 appears in the text without explanation; 117*13 TO omitted before noXv; 118*27 axno omitted before €? 8o? ; 122*36 rovro omitted after avro; i2328 (app. crit.) C appears twice; 139*9 (app. crit.) add vTrep(So\ij ABCu; 139*38 delete colon after eieef; 146*6 manuscript authority for •>} after yap not cited; 180*18 ov bracketed without comment; i8o7 avrdv (transferred here by Wallies from 5) appears without comment. I cannot find authority for the form wpoo-Kei0<uaav (so also Wallies) at iO2i4. RoyalHolloway College, London HUGH TREDENNICK
Fast Occupancy Grid Filtering Using Grid Cell Clusters From LIDAR and Stereo Vision Sensor Data

Occupancy grid filtering is important for navigation and localization in dynamic environments. The techniques that have been proposed in the past research, such as the Bayesian occupancy filter and the sequential Monte Carlo Bayesian occupancy filter, involve the independent consideration of all grid cells and, thus, are inaccurate and computationally expensive. To solve this problem, we propose a fast occupancy grid filtering method that uses a grid state map. We apply a superpixel-based clustering concept called a grid cell cluster (GCC) to 3D particles measured using light detection and ranging and dense depth maps extracted from a stereo vision sensor. The GCC locates a connection among similar data items according to certain criteria. In our proposed method, a GCC consisting of several grid cells has one dynamic state. Thus, we can reduce the computational cost and the number of computational errors by using the same prediction matrices is generated from the grid cells belonging to an object. Our method was evaluated on the KITTI benchmark data set. The results showed that the proposed method was faster (by approximately 38.9%) than Mekahanachas method and approximately 12% more accurate (on the intersection-over-union metric) than prevalent techniques.
Exploitation De La Dynamique Du Geste En Ihm. Application Aux Fonctions De Transfert Pour Le Pointage Et L'extraction D'ÉvÈnements Discrets. (Exploiting The Dynamics Of The Gesture In Hci. Applications To The Transfer Functions For Pointing And Extracting Discrete Events)

La dynamique du geste reste peu exploitee dans le domaine de l'interaction homme-machine alors qu'elle permet de definir des criteres simples d'analyse de l'intention des utilisateurs. Sa principale utilisation porte sur les fonctions de transfert des peripheriques isotoniques. Ces fonctions permettent d'etablir une relation entre le geste de l'utilisateur effectue dans l'espace moteur avec le peripherique de pointage (i.e. souris) et le mouvement du pointeur dans l'espace visuel. Les fonctions de transfert utilisees par les systemes d'exploitation modernes restent cependant fortement meconnues meme si des etudes ont montre qu'elles ont un impact sur les performances des utilisateurs. Pour caracteriser ces fonctions, nous avons developpe un peripherique electronique qui simule une souris reelle et qui permet d'obtenir les fonctions de transfert de tout systeme. Nous avons ainsi pu obtenir les fonctions des systemes Windows, Linux et Mac et nous avons observe des differences notables entre ces fonctions. Nous avons ensuite cherche a optimiser ces fonctions en reduisant au maximum le nombre de leurs degres de liberte. En faisant varier de maniere exhaustive ces parametres, nous avons ainsi pu observe des differences significatives qui montrent qu'il existe une famille de fonctions pour lesquelles les performances sont optimales. Enfin, nous nous sommes interesses a l'utilisation de la dynamique du geste dans un autre contexte, celui de la generation d'evenements discrets, pertinent dans le cadre des interfaces sans contact de type Kinect. Nous avons ainsi montre qu'il est possible de distinguer la selection du deplacement dans une tâche d'interaction 3D. La technique developpee est ensuite amelioree dans le cas des cibles de petites tailles et son application dans un contexte d'interaction 2D est evaluee.
Power Quality Constrained Optimal Management of Unbalanced Smart Microgrids During Scheduled Multiple Transitions Between Grid-Connected and Islanded Modes

In this paper, a novel power quality (PQ) constrained optimization framework for smart microgrids with nonlinear loads is proposed for scheduled multiple transitions between grid-connected and islanded modes. Loads, generation, and energy storage are optimally scheduled to maximize the overall microgrid profit, from selling energy to grid, while satisfying network and PQ constraints. Cost of power interruption to loads, steady-state frequency deviation during islanding, and power sharing among generators are considered. PQ and network constraints of three-phase unbalanced distribution microgrid are given in convex forms. Comprehensive simulation results are given for validating the proposed algorithm and effect of limiting total harmonic distortion on microgrid economics is investigated.
Content Based Video Retrival System for Mexican Culture Heritage Based on Object Matching and Local-Global Descriptors

Multimedia data and networking technologies have had a highly growing during the last decade, with these changes users have changed from text to content based video retrieval systems due to its better performance. We propose a fast content-based video retrieval system which involves the combination of a local descriptor obtained from the speeded-up robust feature algorithm together with an effective and fast object matching operation. To save computational time, compressed video data are partially decoded in order to get discrete cosine transform coefficients of key frames, which are used to obtain sub-block coefficients and a down-sampling version of frames. The preliminary results are ranking using an efficient color descriptor based on color correlogram and dominant color descriptors. To measure the performance of the proposed technique the precision and recall metrics are used. The experimental results show the accuracy of the proposed method applied to a database of Mexican Culture Heritage videos.
New analytical hierarchical process/data envelopment analysis methodology for ranking decision-making units

The analytical hierarchical process/data envelopment analysis (AHP/DEA) methodology for ranking decision-making units (DMUs) has some problems: it illogically compares two DMUs in a DEA model; it is not compatible with DEA ranking in the case of multiple inputs/multiple outputs; and it leads to weak discrimination in cases where the number of inputs and outputs is large. In this paper, we propose a new two-stage AHP/DEA methodology for ranking DMUs that removes these problems. In the first stage, we create a pairwise comparison matrix different from AHP/DEA methodology; the second stage is the same as AHP/DEA methodology. Numerical examples are presented in the paper to illustrate the advantages of the new AHP/DEA methodology.