Miracle-dz/UniFAR-FTUs huggingface dataset:
Another Year Older, Another Year Wiser? Emotion Regulation Strategy Selection and Flexibility Across Adulthood

Several influential theories posit that improvements in emotion regulation contribute to enhanced emotional well-being in older adulthood. However, surprisingly little is known about whether there are age differences in emotion regulation strategy use. We addressed this question by testing whether older adults report using typically adaptive strategies more often and regulate more flexibly than relatively younger adults. In a two-part study, 136 married couples (N = 272) aged 23–85 years completed individual difference measures of cognitive reappraisal and expressive suppression, and then nine daily reports of a broader range of emotion regulation strategies, now including situation selection, situation modification, and distraction. Older adults reported greater habitual use of suppression, but age did not predict situation selection, situation modification, distraction, or reappraisal. In terms of emotion regulation flexibility, a similar number of strategies were reported on a daily basis regardless of the regulator’s age. Unexpectedly, relatively older adults were less variable in their self-reported daily use of each strategy and middle-aged adults were the least variable in their strategy repertoire across different days. These findings counter the common notion that older adults use typically adaptive strategies more than younger adults. Instead, they suggest older adults may be more consistent in their emotion regulation patterns across situations, potentially suggestive of less flexibility. Implications for aging, emotion regulation, and well-being are discussed.
Analysis of Hard-Thresholding for Distributed Compressed Sensing with One-Bit Measurements

A simple hard-thresholding operation is shown to be able to uniformly recover $L$ signals $\textbf{x}_1,. ,\textbf{x}_L \in{\mathbb{R}}^n$ that share a common support of size $s$ from $m = \mathscr{O}(s)$ one-bit measurements per signal if $L \geqslant \ln (en/s)$. This result improves the single signal recovery bounds with $m = \mathscr{O}(s\ln (en/s))$ measurements in the sense that asymptotically fewer measurements per non-zero entry are needed. Numerical evidence supports the theoretical considerations.
Deviant Peer Behavior and Adolescent Delinquency: Protective Effects of Inhibitory Control, Planning, or Decision Making?

We examined relations between adolescent perceptions of deviant peer behavior and delinquency as moderated by inhibitory control, planning, and decision making in the National Institute of Child Health and Human Development (NICHD) Study of Early Child Care and Youth Development at age 15 (N = 991). Adolescents reported perceptions of deviant peer behavior. Inhibitory control, planning, and decision making were assessed behaviorally. Delinquency was evaluated with a latent variable comprised of parent-guardian perceptions of adolescent delinquency and adolescent self-reports. Only inhibitory control moderated the relationship between deviant peer behavior and delinquency, showing that better inhibition protected against delinquency in contexts of high levels of adolescent perceptions of deviant peer behavior. Findings are discussed in the context of theories of adolescent delinquency and risk taking.
The Pilot Establishment and Evaluation of Chinese Affective Words System

Objective:To build the normalized Chinese Affective Words System,this study had completed the determination of the affective dimensions of affective connotations and the normalization of emotional information carried in Chinese nouns,verbs and adjectives.Method:Altogether 124 participants were recruited by advertisements.250 Chinese 2-character nouns were rated by 30 undergraduates,who were selected expediently,as a trial probe into the five emotional information dimensions-pleasure,excitement,dominance,appulsion and familiarity.300 nouns,verbs and adjectives,were evaluated by another 30 university students,as verification of the dimensions.In the third experiment,64 undergraduates assessed 1500 nouns,verbs and adjectives,and 30 of them were selected randomly as the participants for the retest.All tests were taken with a 9-point rating scale.Result:The 4 factors(pleasure,excitement,dominance and familiarity),which contributed more than 98% to the principal constituent,could fully communicate the emotional information of 2-character words.The stimulants determined by the 9-point rating scale could induce a full spectrum of each dimension;and the 4-week interval double tests and tests of different subjects with the same stimulants had shown very good reliability(all more than 0.79),i.e.the average of pleasure,excitement,dominance and familiarity had a strong test-retest reliability.Conclusion:Affective connotation should be expressed fully in all dimensions.Rating of affective connotations of Chinese words can provide normalized stimulant materials for research in cognitive neuroscience.
Correlation between visual-spatial working memory and chinese language cognition of children with developmental dyslexia

【Objective】 To explore visual-spatial sketch Pad function in Chinese developmental dyslexic children.To study the correlation between visual-spatial working memory of subjects and language cognition. 【Methods】 Dyslexic children were chosen according to the International Classification of Diseases-10(ICD-10),and control group was matched for gender,age.All subjects were assessed by written vocabulary skills,phonological processing skills and orthographic skills.Visual matrix span task and Corsi span task were used to measure visual-spatial working memory. 【Results】 The scores of dyslexic children on language cognition were significantly lower on the normal readers(P0.05). The scores of dyslexic children on Visual matrix span task scores and Corsi span task were significantly lower on the normal readers(P0.05). There were significant statistically correlation coefficients between the scores of Visual matrix span task scores and Corsi span task and the scores of written vocabulary skills and orthographic skills.There were no significant statistically correlation coefficients with phonological processing skills(P0.05). 【Conclusions】 Children with developmental dyslexia show deficits in visual-spatial working memory ability.There are significant correlations between visual-spatial working memory and their written vocabulary skills and orthographic skills.
Effect of anatomical backgrounds on detectability in volumetric cone beam CT images

As anatomical noise is often a dominating factor affecting signal detection in medical imaging, we investigate the effects of anatomical backgrounds on signal detection in volumetric cone beam CT images. Signal detection performances are compared between transverse and longitudinal planes with either uniform or anatomical backgrounds. Sphere objects with diameters of 1mm, 5mm, 8mm, and 11mm are used as the signals. Three-dimensional (3D) anatomical backgrounds are generated using an anatomical noise power spectrum, 1/fβ, with β=3, equivalent to mammographic background [1]. The mean voxel value of the 3D anatomical backgrounds is used as an attenuation coefficient of the uniform background. Noisy projection data are acquired by the forward projection of the uniform and anatomical 3D backgrounds with/without sphere lesions and by the addition of quantum noise. Then, images are reconstructed by an FDK algorithm [2]. For each signal size, signal detection performances in transverse and longitudinal planes are measured by calculating the task SNR of a channelized Hotelling observer with Laguerre-Gauss channels. In the uniform background case, transverse planes yield higher task SNR values for all sphere diameters but 1mm. In the anatomical background case, longitudinal planes yield higher task SNR values for all signal diameters. The results indicate that it is beneficial to use longitudinal planes to detect spherical signals in anatomical backgrounds.
Over Sampling for Time Series Classification

The OSTSC package is a powerful oversampling approach for classifying univariant, but multinomial time series data. This vignette provides a brief overview of the over-sampling methodology implemented by the package. A tutorial of the OSTSC package is provided. We begin by providing three test cases for the user to quickly validate the functionality in the package. To demonstrate the performance impact of OSTSC, we provide two medium size imbalanced time series datasets. Each example applies a TensorFlow implementation of a Long Short-Term Memory (LSTM) classifier a type of a Recurrent Neural Network (RNN) classifier to imbalanced time series. The classifier performance is compared with and without oversampling. Finally, larger versions of these two datasets are evaluated to demonstrate the scalability of the package. The examples demonstrate that the OSTSC package improves the performance of RNN classifiers applied to highly imbalanced time series data. In particular, OSTSC is observed to increase the AUC of LSTM from 0.51 to 0.786 on a high frequency trading dataset consisting of 30,000 time series observations. Introduction A significant number of learning problems involve the accurate classification of rare events or outliers from time series data. For example, the detection of a flash crash, rogue trading, or heart arrhythmia from an electrocardiogram. Due to the rarity of these events, machine learning classifiers for detecting these events may be biased towards avoiding false positives. This is because any potential for false positives is greatly exaggerated by the number of negative samples in the data set. Class imbalance problems are most easily addressed by treating the observations as conditionally independent. Then standard statistical techniques, such as oversampling the minority class or undersampling the majority class, or both, are applicable. More (2016) compared a batch of resampling techniques’ classification performances on imbalanced datasets. Besides the conventional resampling approaches, More showed how ensemble methods retain as much original information from the majority class as possible when performing undersampling. Ensemble methods perform well and have gained popularity in the data mining literature. Dubey et al. (2014) studied an ensemble system of feature selection and data sampling from an imbalanced Alzheimer’s Disease Neuroimaging Initiative dataset.
The Association between Sleep Duration and 25-Hydroxyvitamin D Concentration with Obesity in an Elderly Korean Population: A Cross-Sectional Study

Studies have recently reported an association between sleep duration and obesity in some individuals. Vitamin D deficiency is common in elderly populations and is also associated with obesity. In this study, the combined interaction effect of vitamin D levels and sleep duration on obesity-related variables was analyzed in 3757 individuals from an elderly Korean population using the Korean National Health and Nutrition Examination Survey. Significant differences were observed in the interaction effect of the vitamin D levels and sleep duration on obesity-related variables, including BMI (p = 0.004) and the risk of obesity (p < 0.001). Using vitamin D sufficient status and proper sleep duration as a reference, subjects with sufficient vitamin D did not differ in their risk of obesity regardless of their sleep duration. However, the risk of obesity tended to increase with short sleep duration rather than proper sleep duration among subjects who were vitamin D insufficient odds ratio (OR) (95% CI) = 1.293 (1.10–1.657) for proper sleep duration vs. 1.374 (1.066–1.770) for short sleep duration). Only the participants in the vitamin D deficient population who consumed less protein showed an increasing trend in the risk of obesity according to the sleep duration (OR (95% CI) = 1.645 (1.155–2.344) for proper sleep duration and 1.668 (1.156–2.406) for short sleep duration).
Distribution of IL28B rs12979860 and rs8099917 Genotypes in Patients with Chronic Hepatitis C Virus Infection in Tianjin, China.

BACKGROUND Two single-nucleotide polymorphisms (SNPs) rs12979860 (C/T) and rs8099917 (T/G), near the interleukin 28B (IL28B, also known as IFN lambda-3, IFNL3) gene, have a strong association with both spontaneous and treatment-induced hepatitis C virus (HCV) clearance. IL28B polymorphisms have shown a marked differential distribution with regional and ethnic variation. The study aimed to investigate the distribution of IL28B rs12979860 and rs8099917 genotypes in patients with chronic hepatitis C (CHC) in Tianjin, China. METHODS A total of 1,600 patients with chronic HCV infection were enrolled, including 762 males and 838 females. The IL28B rs12979860 and rs8099917 polymorphisms were genotyped via a DNA microarray-based assay. RESULTS The distribution of IL28B rs12979860 CC, CT, and TT genotypes was 93.94%, 5.94%, and 0.12%, and that of rs8099917 TT, TG, and GG genotypes was 88.75%, 11.06%, and 0.19%, respectively. The allele frequencies for rs12979860 C and T were 96.91% and 3.09%, and those for rs8099917 T and G were 94.28% and 5.72%, respectively. The combined assessment of the two SNPs showed that rs12979860 CC/rs8099917 TT was more prevalent with a frequency of 85.94% (1375/1600). When stratified with gender, the genotype and allele distribution of the two SNPs did not significantly differ between male and female subjects. When compared with the data derived from previously reported studies and the 1000 Genomes Project, there was a relatively higher distribution of favorable genotypes rs12979860 CC and rs8099917 TT in the present study. CONCLUSIONS IL28B rs12979860 CC and rs8099917 TT genotypes were predominant in patients with chronic HCV infection in Tianjin, China. These data provided new insight into the geographical frequency distribution of IL28B variants. The higher distribution of the favorable genotypes in Tianjin might be suggestive of better response to antiviral therapy for interferon-eligible CHC patients in this resource-constrained area.
Orthographic Educational Game for Portuguese Language Countries

The new orthographic agreement introduces some changes in the vocabulary of the Portuguese language. Although these changes have modified a small percentage of the vocabulary words, people are struggling to adapt to some of the new orthographic rules. Aiming to mitigate this problem using a ludic approach, we developed Orthographic Educational Game (JOE). JOE focuses predominantly on the rules of accents and hyphens. The game is divided into two modes: training and playing. In the playing mode, the current level of knowledge of the player in orthography is checked and measured. In the training mode, each word comes with a hint related to the rule that is being practiced at the moment. The game was evaluated through an experiment with both undergraduates and high school students. The results indicated that more than 80% of students enjoyed learning orthography through the game-based approach of JOE.
Flap endonuclease overexpression drives genome instability and DNA damage hypersensitivity in a PCNA-dependent manner

Abstract Overexpression of the flap endonuclease FEN1 has been observed in a variety of cancer types and is a marker for poor prognosis. To better understand the cellular consequences of FEN1 overexpression we utilized a model of its Saccharomyces cerevisiae homolog, RAD27. In this system, we discovered that flap endonuclease overexpression impedes replication fork progression and leads to an accumulation of cells in mid-S phase. This was accompanied by increased phosphorylation of the checkpoint kinase Rad53 and histone H2A-S129. RAD27 overexpressing cells were hypersensitive to treatment with DNA damaging agents, and defective in ubiquitinating the replication clamp proliferating cell nuclear antigen (PCNA) at lysine 164. These effects were reversed when the interaction between overexpressed Rad27 and PCNA was ablated, suggesting that the observed phenotypes were linked to problems in DNA replication. RAD27 overexpressing cells also exhibited an unexpected dependence on the SUMO ligases SIZ1 and MMS21 for viability. Importantly, we found that overexpression of FEN1 in human cells also led to phosphorylation of CHK1, CHK2, RPA32 and histone H2AX, all markers of genome instability. Our data indicate that flap endonuclease overexpression is a driver of genome instability in yeast and human cells that impairs DNA replication in a manner dependent on its interaction with PCNA.
Integrated fMRI Preprocessing Framework Using Extended Kalman Filter for Estimation of Slice-Wise Motion

Functional MRI acquisition is sensitive to subjects' motion that cannot be fully constrained. Therefore, signal corrections have to be applied a posteriori in order to mitigate the complex interactions between changing tissue localization and magnetic fields, gradients and readouts. To circumvent current preprocessing strategies limitations, we developed an integrated method that correct motion and spatial low-frequency intensity fluctuations at the level of each slice in order to better fit the acquisition processes. The registration of single or multiple simultaneously acquired slices is achieved online by an Iterated Extended Kalman Filter, favoring the robust estimation of continuous motion, while an intensity bias field is non-parametrically fitted. The proposed extraction of gray-matter BOLD activity from the acquisition space to an anatomical group template space, taking into account distortions, better preserves fine-scale patterns of activity. Importantly, the proposed unified framework generalizes to high-resolution multi-slice techniques. When tested on simulated and real data the latter shows a reduction of motion explained variance and signal variability when compared to the conventional preprocessing approach. These improvements provide more stable patterns of activity, facilitating investigation of cerebral information representation in healthy and/or clinical populations where motion is known to impact fine-scale data.
Pumpkin seed cake as a fishmeal substitute in fish nutrition: effects on growth performance, morphological traits and fillet colour of two freshwater salmonids and two catfish species

ABSTRACT The objectives of this study were to investigate the digestibility of pumpkin seed cake (PSC) for the rainbow trout, Oncorhynchus mykiss (Walbaum, 1792), and effects on performance and product quality traits of four different fish species when PSC partially replaced fishmeal in extruded diets. A digestibility trial was carried out to determine apparent digestibility coefficients (ADC) for crude protein (CP), ether extract (EE) and gross energy (GE) of PSC fed to rainbow trout. In subsequent growth trials, effects on performance and morphological traits and fillet colour values of four different fish species [rainbow trout; brook trout, Salvelinus fontinalis (Mitchill, 1814); African sharptooth catfish, Clarias gariepinus (Burchell, 1822); and wels catfish, Silurus glanis (Linnaeus, 1758)] were evaluated when 60% of fishmeal protein of a reference diet was replaced by PSC protein (based on digestible CP). Nutrient ADC of PSC were high (CP: 89%, EE: 88% and GE: 84%). No significant effects on growth and only minor effects on fillet colour were detected in the trials. However, replacing fishmeal with PSC at the chosen level affected morphological traits and feed conversion in all four species to different extents. Replacement effects of PSC should be tested at lower levels of inclusion before conclusions are drawn on its suitability in fish diets.
A study on in vitro cytotoxicity of cortisol on madin-darby kidney cells

Stress hormones play a vital role in cancer development and tumor formation. However, this mechanism is still obscure. Cortisol plays at several important biochemical roles in disease progress and development. Evaluating the dose-dependent effect of cortisol on MDCK cells is contemplated as the primary task of this experiment. Cell viability did not change significantly following cortisol exposure. Morphologically, no changes were observed in the MDCK cells. However, few cells showed an oval profile. Fluorescent and confocal analysis showed the occurrence of apoptosis significantly at 0.1 mg/L of cortisol. However, the intensity of apoptosis was significantly reduced at higher concentration (0.2 mg/L) of cortisol. The method of qPCR quantitated the mRNA expression of caspase 3, matrix metalloproteinase-9 (MMP-9) and matrix metalloproteinase-2 (MMP-2). Caspase 3 mRNA expression was significantly altered at low concentration (0.1 mg/L) while it was tremendously reduced at the higher level of cortisol (0.2 mg/L). A remarkable increase in the MRNA expression of MMP-2 and MMP-9 was executed in a dose-dependent manner. Our experimental outcome implies that cortisol may induce the apoptosis in MDCK cells.
Transcriptional responses of the marine green alga Micromonas pusilla and an infecting prasinovirus under different phosphate conditions

Prasinophytes are widespread marine algae for which responses to nutrient limitation and viral infection are not well understood. We studied the picoprasinophyte, Micromonas pusilla, grown under phosphate-replete (0.65 ± 0.07 d-1 ) and 10-fold lower (low)-phosphate (0.11 ± 0.04 d-1 ) conditions, and infected by the phycodnavirus MpV-SP1. Expression of 17% of Micromonas genes in uninfected cells differed by >1.5-fold (q < 0.01) between nutrient conditions, with genes for P-metabolism and the uniquely-enriched Sel1-like repeat (SLR) family having higher relative transcript abundances, while phospholipid-synthesis genes were lower in low-P than P-replete. Approximately 70% (P-replete) and 30% (low-P) of cells were lysed 24 h post-infection, and expression of ≤5.8% of host genes changed relative to uninfected treatments. Host genes for CAZymes and glycolysis were activated by infection, supporting importance in viral production, which was significantly lower in slower growing (low-P) hosts. All MpV-SP1 genes were expressed, and our analyses suggest responses to differing host-phosphate backgrounds involve few viral genes, while the temporal program of infection involves many more, and is largely independent of host-phosphate background. Our study (i) identifies genes previously unassociated with nutrient acclimation or viral infection, (ii) provides insights into the temporal program of prasinovirus gene expression by hosts and (iii) establishes cell biological aspects of an ecologically important host-prasinovirus system that differ from other marine algal-virus systems.
The effects of supplemental niacin in laying hen diet on performance and egg quality characteristics

Cette etude a ete effectuee pour determiner les effets de la niacine (0, 250, 500, 1000 et 1500 mg/kg) sur les performances de poules pondeuses. Pendant l'etude, on a employe 120 poules de 30 semaines). On aforme 5 groupes dont chacun contenant 24 poules. L'etude a dure 13 semaines. Elles ont ete alimentees en groupes. L'eau et l'aliment ont ete donnes ad libitum. La production d'oeuf, l'efficacite alimentaire, le poids vif, la resistance des oeufs a la casse ont augmente significativement (p < 0.05). En plus, certains parametres de qualite interieure des oeufs ont ete ameliores effectues avec le niveau d'ajjant de niacine (p < 0.05). En conclusion, la niacine dans la ration peut avoir un effet positif sur la performance des poules pondeuses.