Miracle-dz/UniFAR-FTUs huggingface dataset:
Architectural description of ERS : Analyzing implications of short and long electric road segments

A common architecture is important when there are many different stakeholders involved to facilitate the management of a complex system-of-systems such as Electric Road System (ERS). While ERS has gained recognition as a technological solution, few studies address the necessary system from a holistic perspective. This work addresses the gap by presenting an architecture of a complete ERS. To achieve this, use cases covering many aspects of the electric road were created. The interface between the stakeholders in those use cases were analysed and the activities were broken down. The aim of this paper is to create a common architecture to clarify the interfaces of ERS and to enable interoperability through standardization. The architecture is then used to analyse implications for measuring energy consumption with regard to different electric road segment lengths.
Combine biological experiments, statistical analysis, and semantic search to discover association among high-sensitive C-reactive protein, body fat mass distribution, and other cardiometabolic risk factors in young healthy women

High-sensitivity C-reactive protein (hs-CRP) performs important roles on the onset of metabolic syndrome and cardiovascular diseases (CVD), but little is known about association between hs-CRP and obesity-related metabolic abnormalities in young people without classical CVD risk factors. It thus motivated us to investigate association among hs-CRP, body fat mass (FM) distribution, and other cardiometabolic risk factors in young healthy women. Our approach is based on biological experiments, statistical analysis, and semantic search. Research outcomes in this study resulted in two novel discoveries. Discovery 1: There are four primary determinants for hs-CRP, i.e., central/abdominal FM (a.k.a. trunk FM) accumulation, leptin, high density lipoprotein cholesterol (HDL-C), and plasminogen activator inhibitior-1 (PAI-1). Discovery 2: Chronic inflammation may involve in adipocyte-cytokine interaction underlying the metabolic derangement in healthy young women.
Automated composition of sequence diagrams

Software design is a significant stage in software development life cycle as it creates a blueprint for the implementation of the software. Design-errors lead to costly and insufficient implementation. Hence, it is crucial to provide solutions to discover the design error in early stage of the system development and solve them. Inspired by various engineering disciplines, the software community proposed the concept of modelling in order to reduce these costly errors. Modelling provides a platform to create an abstract representation of the software systems concluding to the birth of various modelling languages such as Unified Modelling Language (UML), Automata, and Petri Net. Due to the modelling raises the level of abstraction throughout the analysis and design process, it enables the system discovers to efficiently identify errors. Since modern systems become more complex, models are often produced part-by-part to help reduce the complexity of the design. This often results in partial specifications captured in models focusing on a subset of the system. To produce an overall model of the system, such partial models must be composed together. Model composition is the process of combining partial models to create a single coherent model. Due to manual model composition is error prone, time-consuming and tedious, it must be replaced by automated model compositions. This thesis presents a novel approach for an automatic composition technique for creating behaviour models, such as a sequence diagram, from partial specifications captured in multiple sequence diagrams with the help of constraint solvers.
CFD INVESTIGATION OF WIRE-WRAPPED FUEL ROD BUNDLES AND FLOW SENSITIVITY TO BUNDLE SIZE

The development of a meshing and simulation procedure for the modeling of a 19 pin wire-wrapped fuel rod bundle is detailed. Parameters varied include base size, prism layer thickness, inlet condition and turbulence model. Care was taken to ensure the flow was highly resolved around walls, and the use of wall functions was avoided. The model was validated against established pressure drop correlations. The meshing and simulation procedure was then used to model 19, 37, and 61 pin fuel rod bundles. Again the pressure drops were compared against and agreed favorably with established pressure drop correlations. The velocity distributions of each bundle were found and analyzed qualitatively and quantitatively to determine at what bundle size interior subchannel velocity distribution can be considered independent of bundle size. A qualitative look at the velocity profiles indicates that the interior subchannels of each bundle were affected by the walls. The quantitative analysis reveals that for interior subchannels, the difference is negligible for certain subchannels. Results indicate that the velocity of the 19 pin bundles centermost subchannels agree within 1% with the corresponding subchannels of the 61 pin bundle, and are thus considered independent of bundle size. The two innermost layers of subchannels in the 37 pin bundle are similarly independent of bundle size. A single layer of subchannels acting as a buffer to wall effects was sufficient to isolate interior subchannels from wall effects.
Interruptible load contracts implementation in stochastic security constrained unit commitment

Providing more choices to customers for determining the cost of their required reliability levels is one of the most important targets of restructured power system. Centralized management of reliability in Vertically Integrated Utility (VIU) applying the same policies to different customers is replaced with decentralized management allowing customers to participate in reliability management based on their required reliability levels. Hence, the importance of implementing interruptible load contracts that specifies each customer's reliability level has been increased in power system studies. In this paper, stochastic programming based on Monte Carlo approach has been used to implement interruptible load contracts in security constrained unit commitment. The performance of the proposed method is demonstrated by applying it to a 6-bus system.
Clarification of a problem abstraction process for TRIZ technical contradiction model in preliminary design

Within the context of resolving innovative design problems, this paper proposes an innovation aid methodology comprises analysis, formulation and resolution of innovative design problems at the behavioral phase of preliminary design. The behavioral phase is characterized by the existence of induced effects, generally imposed by the technical system components structuring, often considered as a source of harmful effects that must be eliminated. Harmful effects are the sort of design problems frequently observed at the preliminary design behavioral phase, they could be formulated as one or more technical contradictions. Contradiction abstraction model has been developed in TRIZ theory (Russian acronym for "Teoriya Resheniya Izobretatelskikh Zadatch" Theory of Resolution of innovative problems). The contradiction model presents an effective resolution tool mostly used for innovative design problems resolution. The tool exploitation difficulty resides in the abstraction process that requires from the TRIZ theory practitioners additional time and experience. In this sense the work presented in this paper proposes an aid methodology for technical contradictions standardized formulating, (ie the problem abstraction according to TRIZ theory), then the resolution exploiting TRIZ contradiction matrix. A classification of the 39 TRIZ engineering parameters was proposed to assist technical contradictions standardized formulating. The developing of this approach involves a whole analyzing of the design process and the main elements of contradiction matrix.
Share of scattered woody vegetation in landscape ecological stability and agriculture sustainability

Supuka, J., Uhrin, P., 2016. Share of scattered woody vegetation in landscape ecological stability and agriculture sustainability. Folia Oecologica, 43: 193–203. Scattered woody vegetation in the agricultural landscape includes more or less fragments of original biotopes and cultivated cultural vegetation as are groves, windbreaks, and infiltration forest belts on slopes, tree alleys, as well as orchards and vineyards. The contribution describes their effectiveness in agriculture sustainability through defined categories of functions and services. At the studied territory, the development of landscape structure was assessed in three time periods of 1869, 1949 and 2010s with regard to the share of scattered vegetation and woody species composition. In 2010, 23 vegetation formations were surveyed, from these 20 are in linear formations and the others in areal formations. Regarding species composition, 47 woody plant species were identified, from these 28 native, 12 alien and 7 fruit trees. The share of scattered vegetation has been proposed to be increased from 5% to 6%. The studied scattered vegetation should be considered as an important contribution to biodiversity conservation, climate, water and soil quality amelioration, pest and disease control and finally crop yield increasing.
The sporulation-specific enzymes encoded by the DIT1 and DIT2 genes catalyze a two-step reaction leading to a soluble LL-dityrosine-containing precursor of the yeast spore wall.

Dityrosine is a sporulation-specific component of the yeast ascospore wall that is essential for the resistance of the spores to adverse environmental conditions. Dityrosine in vivo exists in both the LL and DL configurations and is part of an insoluble macromolecule of unknown structure. Here we present data indicating that dityrosine of the yeast spore wall is biosynthesized by a different mechanism than dityrosine in other biological systems--e.g., the hard fertilization membrane of the sea urchin egg. We identified two soluble, low molecular weight LL-dityrosine-containing spore wall precursors in extracts of sporulating cells and one precursor containing L-tyrosine. By expression of the previously described sporulation-specific genes DIT1 and DIT2 in vegetative cells, it was shown that DIT1 catalyzes the reaction leading from L-tyrosine to the tyrosine-containing precursor. DIT2, which is a member of the cytochrome P450 superfamily, is responsible for the dimerization reaction leading to the dityrosine-containing precursors. Epimerization of LL- to DL-dityrosine is one of the latest steps in spore wall formation and takes place after the dityrosine-containing precursors are incorporated into the spore wall. On the basis of these findings we suggest a biosynthetic pathway for the top layer of the yeast spore wall.
Immunization With a Recombinant MAGE-A3 Protein After High-dose Therapy for Myeloma

MAGE-A3 is frequently expressed in high-risk multiple myeloma (MM). We immunized a healthy donor with MAGE-A3 protein formulated in AS02B to transfer immunity to her identical twin, diagnosed with MAGE-A3-positive MM. After a melphalan 200 mg/m2 syngeneic peripheral blood stem cell transplant, primed donor cells collected after immunizations were transferred and followed by repeated patient immunizations. MAGE-A3 immunizations were well tolerated. Strong MAGE-A3–specific antibody, cytotoxic T-lymphocyte (CTL), and T-helper responses were induced in both twins. A humoral response was transferred to the patient with the donor peripheral blood stem cells and increased by booster immunization. The CTL response targeted a previously undescribed HLA-A*6801 binding MAGE-A3115-123 peptide. MAGE-A3115-123 CTLs were detected in the patient more than 1 year after the last immunization. Multiple T-helper cellular responses were detected with the dominant response to an HLA-DR11 restricted MAGE-A3 epitope. The patient remains in remission 2.5 years after the second transplant. This report shows for the first time that immunization of a healthy donor with a defined cancer-testis protein induces immune responses that can be transferred and expanded posttransplant in the recipient. MAGE-A3 immunization may be a useful adjunct to high dose melphalan-based peripheral blood stem cell transplant, providing a new therapeutic option for high-risk MM.
Comparative Politics and Environmental Taxation: Theory and Quasi-Experimental Evidence

In this paper, we take a step towards understanding the role of democratic institutions on the level of pollution taxation. The theory predicts that presidential-congressional regimes set lower pollution taxes than parliamentary regimes. This results from the checks and balances built into the former, and the higher degree of legislative cohesion in the latter. We test the prediction using the method of propensity score matching along with data on gasoline prices from 86 democratic countries. The empirical evidence is consonant with the theory: we find that ceteris paribus the average price of super gasoline is $0.14 – $0.20 less per liter in presidentialcongressional systems; the average price of diesel gasoline is $0.11 – $0.14 less per liter.
Resveratrol-induced augmentation of telomerase activity delays senescence of endothelial progenitor cells.

BACKGROUND Previous studies have shown that resveratrol increases endothelial progenitor cell (EPC) numbers and functional activity. Increased EPC numbers and activity are associated with the inhibition of EPC senescence. In this study, we investigated the effect of resveratrol on the senescence of EPCs, leading to potentiation of cellular function. METHODS EPCs were isolated from human peripheral blood and identified immunocytochemically. EPCs were incubated with resveratrol (1, 10, and 50 µmol/L) or control for specified times. After in vitro cultivation, acidic β-galactosidase staining revealed the extent of senescence in the cells. To gain further insight into the underlying mechanism of the effect of resveratrol, we measured telomerase activity using a polymerase chain reaction (PCR)-enzyme-linked immunosorbent assay (ELISA) technique. Furthermore, we measured the expression of human telomerase reverse transcriptase (hTERT) and the phosphorylation of Akt by immunoblotting. RESULTS Resveratrol dose-dependently inhibited the onset of EPC senescence in culture. Resveratrol also significantly increased telomerase activity. Interestingly, quantitative real-time PCR analysis demonstrated that resveratrol dose-dependently increased the expression of the catalytic subunit, hTERT, an effect that was significantly inhibited by pharmacological phosphatidylinositol 3-kinase (PI3-K) blockers (wortmannin). The expression of hTERT is regulated by the PI3-K/Akt pathway; therefore, we examined the effect of resveratrol on Akt activity in EPCs. Immunoblotting analysis revealed that resveratrol led to dose-dependent phosphorylation and activation of Akt in EPCs. CONCLUSION Resveratrol delayed EPCs senescence in vitro, which may be dependent on telomerase activation.
multi-temporal UAV photography Mapping landslide displacements using Structure from Motion ( SfM ) and image correlation of

In this study, we present a flexible, cost-effective, and accurate method to monitor landslides using a small unmanned aerial vehicle (UAV) to collect aerial photography. In the first part, we apply a Structure from Motion (SfM) workflow to derive a 3D model of a landslide in southeast Tasmania from multi-view UAV photography. The geometric accuracy of the 3D model and resulting DEMs and orthophoto mosaics was tested with ground control points coordinated with geodetic GPS receivers. A horizontal accuracy of 7 cm and vertical accuracy of 6 cm was achieved. In the second part, two DEMs and orthophoto mosaics acquired on 16 July 2011 and 10 November 2011 were compared to study landslide dynamics. The COSI-Corr image correlation technique was evaluated to quantify and map terrain displacements. The magnitude and direction of the displacement vectors derived from correlating two hillshaded DEM layers corresponded to a visual interpretation of landslide change. Results show that the algorithm can accurately map displacements of the toes, chunks of soil, and vegetation patches on top of the landslide, but is not capable of mapping the retreat of the main scarp. The conclusion is that UAV-based imagery in combination with 3D scene reconstruction and image correlation algorithms provide flexible and effective tools to map and monitor landslide dynamics.
The relationship between the big five personality factors with blood types in Iranian university students

The big five model of personality has been consider e by many psychologists as a popular and powerful approach for the study of personality characteristics. These include neuroticism, extraversion, openness, agree ableness, and conscientiousness. Recognition of blood types could help in the recognition personality traits. This is a descripti ve and correlation study. 400 people were enrolled in the study using the convenience sampling method. Th e 60-item NEO-PI was used for data collection. Data entered i nto SPSS version 18 and analyzed using descriptive statistics including frequency distribution tables , mean, standard deviation, Kolmogorov-Smirnov test , one-way ANOVA and post hoc LSD tests. Mean of neuroticism in blood ty pe O and blood type B had the highest (23.83) and l owest scores (22.28) respectively. Mean of extraversion in blood type A and blood type B had the highest (30.76) an d the lowest score (28.67) respectively. Mean of openness in blo od type A and blood type AB had the highest (25.72) and the lowest score (23.93) respectively. Means of agreeab l ness and conscientiousness in blood type A had th e highest scores of 30.16 and 35.47 respectively. In this stu dy, personality factors of openness and extraversio n were associated with different blood types (p = 0.04). F rom the five-factor personality traits, the three f actors of Neuroticism, Conscientiousness and Agreeableness sh owed no relationship with blood types; however, bot h Extraversion and Openness were linked with differen t blood types.
Analysis of Emphasis on Japanese-English Bilingual Corpora

Conventional speech-to-speech (S2S) translation [1] systems only translate the content of the utterance and ignore paralinguistic information included in the input speech. As a step towards addressing this limitation, in this paper we analyze paralinguistic information across languages. Among the various types of paralinguistic information, we focus on emphasis, a type of information that is used to convey the focus of the sentence. Emphasis is an important factor especially when repeating an initially misheard sentence (a situation that occurs often when using less-than perfect speech translation systems). This paper describes an analysis regarding how emphasis is expressed across two languages: Japanese and English.
Amplification and overexpression of the MET gene in intrahepatic cholangiocarcinoma correlate with adverse pathological features and worse clinical outcome

Intrahepatic cholangiocarcinoma (iCCA) is the second most common primary hepatic malignancy, and remains a challenge to treat. At the molecular level, the hepatocyte growth factor/MET pathway is one of the most commonly activated signaling pathways in malignancies. Several studies have reported MET overexpression in human iCCAs, at varying frequencies. However, there is no consensus regarding the impact of MET overexpression on prognosis. The correlation between MET overexpression and gene amplification in iCCAs has not been explored. We obtained tissue samples from 86 patients with primary iCCAs, and performed immunohistochemical analysis of MET expression. Quantitative real-time polymerase chain reaction was also performed to examine MET amplification. MET overexpression was found in 39 of 86 cases (45.35%). It was significantly associated with older age, presence of hepatolithiasis, higher cancer stage, and more advanced primary tumor. MET overexpression was also a predictive factor for adverse outcome with shorter disease-free survival. MET amplification was detected in 10 cases of 84 cases (11.90%), and was significantly associated with larger tumor size (more than 5 cm) and shorter overall survival. There was no significant correlation between MET overexpression and gene amplification. Revealing the clinicopathological features of MET overexpression and amplification would assist in the development of personalized treatment for iCCAs.
PRELIMINARY STUDY ON Pd-BASED BINARY CATALYSTS SUPPORTED WITH CARBON NANOFIBER FOR THE ELECTROOXIDATION OF GLYCEROL ( Kajian Awal ke atas Mangkin Berasaskan Pd Disokong dengan Gentian

In this study, Aurum (Au) was used as the second metal in palladium catalyst (Pd) and carbon nanofiber (CNF) as catalyst support for glycerol oxidation. Second metal and catalyst support will help to improve catalytic activity and decrease adsorbed oxidation intermediates species. Carbon nanofiber supported PdAu nanoparticles was synthesized by using trisodium citrate as stabilizing agent and sodium borohydride as reducing agent. Physicochemical characterizations of the catalyst were performed by X-ray Diffraction (XRD), Transmission Electron Microscope (TEM), Field Emission Scanning Electron Microscope (FESEM) and Brunauer-Emmett-Teller (BET) to study the nature of the catalysts. The electrochemical activity for oxidation of glycerol on PdAu/CNF was evaluated in half cell under alkaline media by cyclic voltammetry potentiostat. The densities and mass activity obtained from half-cell analysis were 73.81 mA cm-2 @ 492.04 mA mg-1, 63.82 mA cm-2 @ 425.44 mA mg-1 and 55.73 mA cm-2 @ 371.54 mA mg-1 for PdAu/CNF, Pd/CNF and Au/CNF, respectively in 1 M KOH + 0.5 M glycerol electrolyte. The electrochemical study, exhibited the superior performance of bimetallic PdAu/CNF catalyst as compared to monometallic Pd/CNF. This indicate that the electronic coupling between Pd and Au can promote the electrocatalytic activity for glycerol oxidation.