Miracle-dz/UniFAR-FTUs huggingface dataset:
Proposed guidelines for diagnosing chronic active Epstein‐Barr virus infection

Since the initial report of unusual manifestations possibly associated with chronic active Epstein‐Barr virus (EBV) infection (CAEBV), nearly three decades have passed. During this period, reported cases with this entity have dramatically increased in the world. Additionally, recent development of diagnostic procedures, including molecular biological and immunological techniques, have provided us with the ability to define certain diseases, especially malignant disorders. Guidelines, derived mainly from the current literature and recent experiences with CAEBV in Japan, for diagnosing CAEBV are proposed to clarify this enigmatic disease. Am. J. Hematol. 80:64–69, 2005. © 2005 Wiley‐Liss, Inc.
School Closure to Reduce Influenza Transmission

We agree with Koonin and Cetron (1) that early application of any intervention during an influenza epidemic or pandemic is critical in maximizing population health benefits. Further, the longer an intervention is sustained, the greater the likely benefit. Whether surveillance data can inform public health interventions may depend on the timeliness of the data as well as the length of the epidemic. In tropical and subtropical settings, influenza tends to circulate longer. Although duration of the epidemic could enable delayed interventions a chance of success, social distancing interventions may need to be sustained to ensure that the epidemic does not revive when the intervention period ends. One important study not mentioned by Koonin and Cetron is a natural experiment in France where the staggering of school holiday periods in different regions enabled Cauchemez et al. to estimate that school holidays prevent 16%–18% of seasonal influenza cases (2). In contrast to our study of a single school closure event in response to 1 seasonal outbreak, the French study considered preplanned holiday periods spanning many years. Although pandemic plans often describe action to be taken depending on features in the epidemic curve (e.g., the acceleration interval as the upslope of the epidemic curve), we would argue that more focus should be given to underlying transmission dynamics. In our analysis of the effect of school closures in Hong Kong, we used a simple statistical technique (3) to estimate the underlying reproductive number. Changes in the epidemic curve may lag behind changes in the underlying transmission dynamics by at least 1 serial interval, as has previously been shown for severe acute respiratory syndrome (3–5). Public health practitioners must be encouraged to use these methods routinely. Finally, we concur that a multipronged, targeted, layered approach will likely provide the best mitigation strategy in the event of a pandemic. However, we caution against conflating good public health practice of “pulling out all the stops” in the event of a pandemic with good scientific practice of evaluating the independent effect of school closures, which was the object of our article.
CLK / DYRK kinases inhibitor Leucettine L 41 induces mTOR-dependent autophagy . Implication for Alzheimers ’ disease

C.N. R.S. , USR3151, ‘Protein Phosphorylation & Human Disease’, Station Biologique, place Georges Teissier, CS 90074, 29688 Roscoff Cedex, FRANCE (XF, ED). Inserm/UPS UMR 1048, ‘Production et fonctions plaquettaires: signalisation et phosphoinositides’ group, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), 1, Avenue Jean Poulhès, BP 84225, 31432 Toulouse cedex 4, FRANCE (GC, BP). Department of Physiology, Wayne State University School of Medicine, 540 E. Canfield, Detroit, MI 48201, USA (DS, AS). Laboratoire Sciences Chimiques de Rennes, UMR CNRS 6226, Groupe Ingénierie Chimique & Molécules pour le Vivant (ICMV), Université de Rennes 1, Bât. 10A, Campus de Beaulieu, Avenue du Général Leclerc, CS 74205, 35042 Rennes cedex, FRANCE (EL, FC, JPB). ManRos Therapeutics, Perharidy Research Center, 29680 Roscoff, Bretagne, FRANCE (LM). Molecular Pharmacology Fast Forward. Published on December 23, 2013 as doi:10.1124/mol.113. 090837
Automatic Beam Hardening Correction For CT Reconstruction

In computed tomography (CT) the quality of reconstructed images depends on several reasons: the quality of the set-up calibration; precision of the mathematical model, used in the reconstruction procedure; the reconstruction technique used; quality of the numerical implementation of the reconstruction algorithm. Most of fast reconstruction algorithms use the X-ray monochromaticity assumption. If we apply the algorithms to reconstruct the images from the projections measured in polychromatic mode then the reconstructed images will be corrupted by so-called cupping artifacts due to beam hardening. There are several approaches to take into account polichromaticity. One of them is to correct the sinograms before reconstruction. This paper presents the usage of Radon invariant to estimate the gamma parameter in the procedure of the sinogram correction for beam hardening (BH).
Generalized Hamming weights of linear codes

The generalized Hamming weight, d/sub r/(C), of a binary linear code C is the size of the smallest support of any r-dimensional subcode of C. The parameter d/sub r/(C) determines the code's performance on the wire-tap channel of Type II. Bounds on d/sub r/(C), and in some cases exact expressions, are derived. In particular, a generalized Griesmer bound for d/sub r/(C) is presented and examples are given of codes meeting this bound with equality. >
Constraining extra space dimensions using precision molecular spectroscopy

Highly accurate measurements of quantum level energies in molecular systems provide a test ground for new physics, as such effects could manifest themselves as minute shifts in the quantum level structures of atoms and molecules. For the lightest molecular systems, neutral molecular hydrogen (H2, HD and D2) and the molecular hydrogen ions (H+2, HD+ and D+2), weak force effects are several orders weaker than current experimental and theoretical results, while contributions of Newtonian gravity and the strong force at the characteristic molecular distance scale of 1 Å can be safely neglected. Comparisons between experiment and QED calculations for these molecular systems can be interpreted in terms of probing large extra space dimensions, under which gravity could become much stronger than in ordinary 3-D space. Under this assumption, using the spectra of H2 we have derived constraints on the compactification scales for extra dimensions within the Arkani-Hamed-Dimopoulos-Dvali (ADD) framework, and constraints on the brane separation and bulk curvature within the Randall-Sundrum (RS-I and RS-II) frameworks.
SOME POSSIBLE EFFECTS OF NURSING ON THE MAMMARY GLAND TUMOR INCIDENCE IN MICE.

A preliminary report on some possible effects of nursing on the mammary gland tumor incidence in mice is presented. 3 litters of mice from an inbred strain of mice with a mammary gland tumor incidence of 88% were fostered by a strain of mice with a tumor indicence of about 10%. Of the 9 females fostered by the low tumor strain 3 developed mammary gland tumors 4 had primary lung tumors and 2 died nontumorus. Among 40 of their progeny who were fostered 12 developed breast tumors 2 had breast and pulmonary cancers 13 had primary lung tumors and 13 died nontumorus. 10 of the 13 progeny of the fostered females which had breast cancer developed similar growths as compared with 4 of the 24 progeny from fostered females which had lung tumors. The respective proportions were 77% and 17%. These results support the belief in the extrachromosomal influence as a cause in the development of mammary tumor.
Implementation of a fast coral detector using a supervised machine learning and Gabor Wavelet feature descriptors

The task of reef restoration is very challenging for volunteer SCUBA divers, if it has to be carried out at deep sea, 200 meters, and low temperatures. This kind of task can be properly performed by an Autonomous Underwater Vehicle (AUV); able to detect the location of reef areas and approach them. The aim of this study is the development of a vision system for coral detections based on supervised machine learning. In order to achieve this, we use a bank of Gabor Wavelet filters to extract texture feature descriptors, we use learning classifiers, from OpenCV library, to discriminate coral from non-coral reef. We compare: running time, accuracy, specificity and sensitivity of nine different learning classifiers. We select Decision Trees algorithm because it shows the fastest and the most accurate performance. For the evaluation of this system, we use a database of 621 images (developed for this purpose), that represents the coral reef located in Belize: 110 for training the classifiers and 511 for testing the coral detector.
Developing a cultural competence inventory for nurses in China

AIM To develop and psychometrically test the Cultural Competence Inventory for Nurses in China. BACKGROUND Cultural competence is expected worldwide from nurses due to the increasing cultural diversity of people in healthcare establishments. Yet, no cultural competence framework or instrument for nurses has been identified to guide nursing practice in China where the cultural diversity of the populations and the characteristics of the healthcare system are different from those of the West. METHODS A review of literature and individual interviews among nurse experts generated 74 items, which were evaluated by six experts in transcultural nursing. A stratified random sampling technique was used to recruit 520 Chinese nurses for the field test. Construct validity and internal consistency reliability of the instrument were estimated by exploratory factor analysis and Cronbach's alpha, respectively. The data were collected from May 2015 to January 2016. RESULTS The final instrument consists of 29 items in five dimensions, namely 'cultural awareness, cultural respect, cultural knowledge, cultural understanding and cultural skills'. Cronbach's alpha for the instrument was 0.94, with a range of 0.79-0.92 for the individual dimensions. The evidence for contrast-group validity (P < 0.001) was also obtained. CONCLUSION The study provides evidence that the Cultural Competence Inventory for Nurses in China is reliable, valid and culturally sensitive for measuring nurses' cultural competence. The instrument development process facilitates the understanding of cultural competence globally. IMPLICATIONS FOR NURSING AND NURSING POLICY Cultural competence of nurses can be evaluated for self-development, workforce management and quality assurance. The instrument can also serve as the foundation to develop education curricula and nursing procedures or protocols to improve culturally competent nursing practice.
Solving Multi-Item Capacitated Lot-Sizing Problems Using Variable Redefinition

Mixed-integer programming models are typically not used to solve realistic-sized production scheduling problems because they require exorbitant solution times. We impose a useful taxonomy on production scheduling problems and develop alternative formulations for a wide variety of problems within the taxonomy. The linear programming relaxation of the new models is very effective in generating bounds. We show that these bounds are equal to those that could be generated using Lagrangian relaxation or column generation. The linear programming bounds increase in effectiveness as the problems become larger. Perhaps of greatest significance is that practitioners can obtain our results using only standard “off-the-shelf” codes such as LINDO or MPSX/370. We report computational experience in several computing environments (hardware and software) on problems with up to 200 products and 10 time periods (2000 0-1 variables).
A Signal Subspace Speech Enhancement Method for Various Noises

In this paper, we propose a single-channel speech enhancement method in terms of subspace techniques to reduce the noises from speech signals in various noises environment. This subspace approach based on Karhunen-Loeve transform and implemented via Principal component analysis. The optimal subspace selection is provided by a minimum description length criterion. An offset factor generated from the white noise was used to modify the variance to adapt to the specified colored noise. Several objective speech quality measures have been introduced to give an overall evaluation of the proposed method. A large amount of data and figures, as well as the audio quality evaluation results, testify that the algorithm provides high performance for the input signal-to-noise ratio range from -5dB to 10dB. It is showed that the proposed approach have excellent characteristics for colored noises in strong background noise environment with lower signal-to-noise ratio. DOI: http://dx.doi. org/10.11591/telkomnika.v11i2. 1999 Full Text: PDF
Statistical evaluation of tablet coating processes: influence of pan design and solvent type

Partially and fully perforated pan coaters are among the most relevant types of equipment currently used in the process of coating tablets. The goal of this study was to assess the performance differences among these types of equipment employing a factorial design. This statistical approach allowed the simultaneous study of the process variables and verification of interactions among them. The study included partially-perforated and fully-perforated pan coaters, aqueous and organic solvents, as well as hypromellose-based immediate-release coating. The dependent variables were process time, energy consumption, mean weight of tablets and process yield. For the tests, placebo tablets with a mean weight of 250 mg were produced, divided into eight lots of two kilograms each and coated in duplicate, using both partially perforated pan and fully perforated pan coaters. The results showed a significant difference between the type of equipment used (partially and fully perforated pan coaters) with regard to process time and energy consumption, whereas no significant difference was identified for mean weight of the coated tablets and process yield.
Sound transmission through a periodic cascade with application to drill pipes

Acoustical data transmission through the wall of drill pipes is considered. Drill pipes are known to behave like bandpass filters; the position of the pass bands can be determined analytically. This work extends the frequency domain drill pipe models presented by Barnes and Kirkwood [J. Acoust. Soc. Am. 51, 1606–1608 (1972)], and more recently by Drumheller [J. Acoust. Soc. Am. 85, 1048–1064 (1989)]. The approach discussed in this paper has the advantage that it yields explicit expressions for the fine structure of the drill pipe’s frequency response in the pass bands. It furthermore allows the effect of energy dissipation and pipe segment length variations to be included in the model. The emphasis of the paper, however, lies on the time domain modeling of the drill pipe. The propagation of sound energy pulses through its wall, and the effect of multiple reflections and/or transmissions during this propagation, are described using a Markov chain. Explicit expressions result for the expected duration of an.
Network awareness: social network search, innovation and productivity in organisations

The 50-year tradition of social network analysis has much to offer modern organisations. At one level, it has shown ways to see how informal organisation influences the formal one. At another it has been able to show some of the patterns of human interaction that lead to innovation and creativity. The ability to use this knowledge to improved productivity, innovation and decision making requires understanding of the influence of network structures on the individual and the organisation, and knowledge of how the individual and organisational institutions affect the networks. This paper gives examples of this and introduces the concept of network awareness. Network awareness is a multileveled concept that includes people's awareness of the networks around them, the strategy of becoming more aware of networks, and the processes and tools to help aid this strategy.
Noise suppression using one-regular Unimodular filterbanks

In this paper one-regular Unimodular filterbank (UMFB) is used for subband based noise reduction in speech signals. The regularity property of the filterbank enables a better estimate of the noise characteristics at low frequencies. This results in effective reduction of noise when compared with conventional filterbanks. Unimodular filterbanks have the lowest possible system delay of M -1 samples, where M is the number of channels. Hence, we show that effective noise reduction in speech signals can be obtained, with UMFB, at a very low system delay. The implementation of UMFB is done with simple structures having low computational complexity. The results are validated with suitable experiments.
D-erythro-neopterin biosynthesis in the methanogenic archaea Methanococcus thermophila and Methanobacterium thermoautotrophicum deltaH

The steps in the biosynthetic transformation of GTP to 7,8-dihydro-D-erythro-neopterin (H2neopterin), the precursor to the modified folates found in the methanogenic archaea, has been elucidated for the first time in two members of the domain Archaea. In Methanococcus thermophila and Methanobacterium thermoautotrophicum deltaH, it has been demonstrated that H2neopterin 2':3'-cyclic phosphate is an intermediate in this conversion. In addition, the formation of the pterin ring of the H2neopterin 2':3'-cyclic phosphate is catalyzed not by a single enzyme, as is known to occur with GTP cyclohydrolase I in the Eucarya and Bacteria, but rather by two or more enzymes. A 2,4,5-triamino-4(3H)-pyrimidinone-containing molecule, most likely 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-triphosphate, has been identified as an intermediate in the formation of the H2neopterin 2':3'-cyclic phosphate. Synthetic H2neopterin 2':3'-cyclic phosphate was found to be readily hydrolyzed by cell extracts of M. thermophila via the H2neopterin 3'-phosphate to H2neopterin, a known precursor to the pterin portion of methanopterin.
Real-Time Augmentation of a Newspaper Using Computer Vision

The following dissertation aims to augment an adapted newspaper using the combination of a projector and computer vision methods. The final aim is for video footage to be projected onto the newspaper and to appear as if it is printed on the newspaper, as seen on the Daily Prophet in the Harry Potter films. The projection should be correctly transformed to correct distortions. The technical side of this dissertation is mostly related to augmented workstations, desks and textbooks which were introduced in the early 1990s. Most of these prototypes aimed to improve physical notes by digitizing them, which has now been accomplished through tablets. This dissertation is justified as an interesting application of computer science or computer vision. It can be used as a fun prototype to increase interest in the field or just to serve as entertainment for others. The adapted newspaper is fitted with fiduciary marks for the system to detect. These marks must be identified and labelled as the system requires information for each of the four corners to transform the projection. Two different identification methods were completed each with their own limitations, namely the assumption method and the colour method. The colour method was designed to overcome limitations of the assumption method and is more complex, this has resulted in limitations of its own. Both methods have the ability to correctly transform the projection into to the right location on the newspaper once the testing environment is ideal (especially for the colour method as it is very sensitive to the environment’s lighting). Both methods also experience a lag when updating the projection which is presumably related to costly computation times of the required algorithms or a lag in the projector. Aside from this the application can still be used in a number of environments and can still offer entertainment for those using it.
An air-liquid interface promotes the differentiation of gastric surface mucous cells (GSM06) in culture.

The gastric surface epithelium is situated at an air-liquid interface because the luminal surface of the alimentary tract is in continuity with the air phase. However, the effects of this microenvironment on the gastric epithelium remain unclear. The aim of this study was to clarify the effects of an air-liquid interface on gastric epithelial cell biology. Gastric surface mucous cells (GSM06) were cultured at an air-liquid interface. Cultured cells were examined by histology, histochemistry, and transmission electron microscopy. When the cells were cultured at an air-liquid interface, the surface cells on the collagen gel became tall columnar and secreted periodic acid-Shiff-positive substances at the apical surface. These cells indicated many mucous granules in the apical cytoplasm and organized the basal lamina at the contact side with the gel. In contrast, under immersed condition, the surface cells showed immature features. This is the first report of an air-liquid interface promoting the differentiation of gastric surface mucous cells in a reconstruction culture of the gastric surface epithelial layer, suggesting that an air-liquid interface may function as a crucial luminal factor to maintain the homeostasis of gastric mucosa.
Backstepping speed control of PMSM based on equivalent input disturbance estimator

This paper presents an improved equivalent input disturbance estimator to solve the influence of unmeasured disturbance on permanent magnet synchronous motors (PMSM). Backstepping controller is designed and the combination of the state observer and the low-pass filter is used in the estimator. The controller and estimator satisfy the separation principle by using the estimator presented. The simulation results show that the design method can overcome the shortcomings of long settling time compared with the traditional method and improve the disturbance rejection performance.
Sensor pillow system: Monitoring cardio-respiratory and posture movements during sleep

In this paper, we have developed a sleep monitoring and gesture recognition system for patient based on polysomnography which will be useful for patient communication with healthcare personals and/or relatives. In particular, we present the sensor pillow system that employs wireless networks based on low-cost ZigBee technology and a sensor array of force sensitive resistors (FSR) based on polymer thick film (PTF) device for classifying and recognizing sleep posture. This paper also proposes a simple motion model that explains the change of the head pressure distribution. In addition, we can detect some physiological parameters during the sleep stages and wakefulness as well as record cardio-respiratory activity as related to different physiological factors. The integration of the sensor system and wireless technology with a computer software could make this healthcare monitoring system a commercial product valuable for point-of-care applications.