Miracle-dz/UniFAR-FTUs huggingface dataset:
Viewing Cell Movements in the Developing Neuroendocrine Brain1

Abstract Many studies suggest that migratory guidance cues within the developing brain are diverse across many regions. To better understand the early development and differentiation of select brain regions, an in vitro method was developed using selected inbred and transgenic strains of embryonic mice. In particular, organotypic slices are used to test factors that influence the movements of neurons during brain development. Thick 250 μm slices cut on a vibrating microtome are prepared and maintained in vitro for 0–3 days. Nissl stain analyses often show a uniform distribution of cells in the regions of interest on the day of plating (embryonic days 12–15). After 3 days in vitro, cellular aggregation suggesting nuclear formation or the changing position of cells with a defined phenotype show that reasonably normal cell movements occur in several regions. Movements in vitro that mimic changes in vivo suggest that key factors reside locally within the plane of the slices. Video microscopy studies are used to follow the migration of fluorescently labeled cells in brain slices from mice maintained in serum-free media for 1 to 3 days. Transgenic mice with selective promoter driven expression of fluorescent proteins allow us to view specific cell types (e.g., neurons expressing gonadotropin-releasing hormone). The accessibility of an in vitro system that provides for relatively normal brain development over key brief windows of time allows for the testing of important mechanisms.
Public Opinion on the Harshness of Local Courts

Drawing on framing theory, the present study tests the impact of question wording on people’s reported opinions about the harshness of their local courts. A randomized experimental design tested two salient variations against the standard wording used in the National Opinion Research Center’s General Social Survey (GSS). The results indicated statistically significant differences, with fewer respondents expressing a desire for greater harshness with the alternative forms than the standard question form. Four of the five correlates that the authors examined also showed differential relationships with punitiveness among the question forms. These findings suggest that scholars should carefully consider the meaning of people’s responses when interpreting the GSS question as an indicator of public punitiveness.
Metaphor in Organization Theory: Progress and the Past

This article presents a response to an article written by Cliff Oswick and Philip Jones in which they criticized Joep Cornelissen's article, “Beyond Compare: Metaphor in Organization Theory. ” The author appreciates their comments for stimulating discussion about the role and use of metaphors within organizational theory. He addresses Jones and Oswick's critical comments regarding the generalizability of the domains-interaction model as well as their proposal to treat the comparison and domains-interaction models as complementary sociological and psychological tools for studying the uses and impact of metaphors in organization theory.
Articulating a foreign language sequence through content: A look at the culture standards

Curricular articulation and the integration of cultural knowledge with language development over extended sequences are among the most persistent challenges for contemporary language teaching and learning. The paper examines the nature of those challenges in light of theories of language and culture while using as the site of investigation the culture standards that have been developed within the framework of the Standards for Foreign Language Learning, a key document for L2 education in the United States, particularly at the K-12 level. Taking four perspectives, it suggests ways in which simultaneous content and language teaching might be tackled through a genre-based way of constructing extended curricula and by using genre-based tasks for informing pedagogical decisions. In this fashion, learners might be able to progress toward a competent cultural literacy that is language-based.
Control movement of mobile robots inside building based on pattern recognition algorithm

In the movement management system of mobile robots, simultaneous detection of obstacles and creation of obstacles' map in the near field of the mobile robot are extremely urgent and complex tasks. In general, environment around robot is very complicated due to differences in change of lighting conditions and viewing angles. These problems lead to decrease accuracy of obstacles recognition. In this paper, we propose algorithms to solve this problem and increase effectiveness of mobile robots: to detect obstacles and create map of environment around robots could be used algorithm, which based on 3D-point cloud. In addition, algorithm “SURF” is implemented to detect landmark. Using this algorithm allows satisfying requirements for obstacle detection in real time. The experimental results show the effectiveness of proposed approach using in vision system of a mobile robot platform.
CUNY-BLENDER TAC-KBP2010 Entity Linking and Slot Filling System Description

The CUNY-BLENDER team participated in the following tasks in TAC-KBP2010: Regular Entity Linking, Regular Slot Filling and Surprise Slot Filling task (per:disease slot). In the TAC-KBP program, the entity linking task is considered as independent from or a pre-processing step of the slot filling task. Previous efforts on this task mainly focus on utilizing the entity surface information and the sentence/document-level contextual information of the entity. Very little work has attempted using the slot filling results as feedback features to enhance entity linking. In the KBP2010 evaluation, the CUNY-BLENDER entity linking system explored the slot filling attributes that may potentially help disambiguate entity mentions. Evaluation results show that this feedback approach can achieve 9.1% absolute improvement on micro-average accuracy over the baseline using vector space model.
Cardiac cells control transmitter release and calcium homeostasis in sympathetic neurons cultured from embryonic chick.

1. The contribution of target cells in controlling the functional properties of sympathetic neurons was investigated using pure neuronal cultures and co‐cultures of neurons with their physiological target cells. 2. Chick embryo sympathetic neurons cultured alone exhibited maximal elevation of cytosolic free Ca2+ ([Ca2+]i) and release of tritiated noradrenaline ([3H]NA) when given ten stimulating pulses at 1 Hz but not at 10 Hz, yielding a negative frequency‐release response. Stimulation‐evoked release was only slightly enhanced by the K+ channel blocker tetraethylammonium (TEA, 10 mM). 3. When sympathetic neurons were co‐cultured with cardiac cells of the chick embryo, electrically stimulated transmitter release and neuronal [Ca2+]i were reduced by 3‐ to 5‐fold. Co‐cultured neurons had a positive stimulation frequency‐‐[3H]NA release response and 5‐ to 7‐fold facilitation of release by TEA. 4. Voltage‐clamped Ca2+ current density was decreased from 0.61 +/‐ 0.13 pA micron‐2 in neurons alone to 0.19 +/‐ 0.03 pA micron‐2 in co‐cultured neurons. 5. Neonatal rat superior cervical ganglion (SCG) neurons were also relatively insensitive to TEA when cultured alone, but [3H]NA release was greatly facilitated by TEA when tested in SCG neurons co‐cultured with rat neonatal cardiac myocytes. 6. The cardiac cell‐induced changes in Ca2+ handling and release properties were produced within 24 h by sympathetic neuroeffector cells, but not by skeletal muscle cells or sensory neurons, and did not occur spontaneously in neurons grown alone for up to 6 days. 7. The frequency and TEA responses of neurons grown with cardiac cells are characteristic of responses seen in sympathetic neuroeffector organs. We conclude that physiological targets play a crucial role in development of normal transmitter‐release properties by controlling Ca2+ homeostasis in sympathetic neurons.
José Eduardo Agualusa, and Other Possible Lusofonias

Este ensaio procura pensar a relação entre o discurso luso-tropicalista e o discurso da lusofonia. Depois de traçar algumas das posições e polêmicas associadas com a articulação contemporânea da lusofonia, desenvolve-se uma leitura ampla da obra do escritor angolano, José Eduardo Agualusa, um dos principais protagonistas de uma configuração literária da lusofonia. A relação entre sua obra e elementos do discurso luso-tropical, proponho, pode ser entendida como uma de ambivalência pós-colonial, isto é, de apropriação, re-escrita, ou escrita do “texto” luso-tropical que indelevelmente a precede.
Habits of mind and academic endeavors : The correlates and consequences of achievement goal orientations

The purpose of this study was to examine factors that influence students’ situational construals and the consequences of those construals in terms of task engagement and performance. A theoretical framework was laid out which outlined the dynamic processes of self-regulation in learning and performance. It was suggested that the goals and outcomes students favor and pursue are crucial determinants of how students approach academic tasks. Two major forms of selfregulation were identified; one with a focus on gaining personal resources, and another with a focus on restoring the balance in personal well-being. The tendency to engage in different variants of these basic forms of self-regulation was presumed to be reflected in the patterning of different achievement goal orientations. The general research questions of the study were as follows: (1) What sort of goal orientations and goal orientation profiles can be identified among comprehensive school students? (2) How generalizable are goal orientations in relation to gender and cultural background? (3) How do students with different goal orientation profiles differ with respect to motivational beliefs, situational appraisals, and indices of school achievement and task performance? (4) How do students’ taskrelated experiences and performance vary as a function of different instructional conditions? Four empirical studies addressed these questions: Study I looked at the patterning of goal orientations, motivational beliefs, and school performance as such and in relation to gender; Study II examined the generalizability of goal orientations, causality beliefs, and their relationships across different cultural backgrounds; Study III investigated the influence of the instructional condition on differently oriented students’ situational appraisals and task performance; and Study IV explored the role situational appraisals play in mediating the influence of goal orientations and causality beliefs on task performance, as well as gender differences in these effects and on variable means. The role of achievement goal orientations was examined from both variablecentered and person-centered perspectives. Several types of goal orientations and configurations of goal orientations were identified. The results of the empirical studies showed that different achievement goal orientations were uniquely associated with criterion variables such as action-control beliefs, self-perceptions, selfreported learning strategy use, situation-specific motivational judgments, and taskperformance. Findings from the person-centered analyses paralleled these results. For the most part, these results concurred with those of prior studies. The types of goal orientations identified were not dependent on gender or nationality, although group differences were found for variable means. Regarding the effects of cultural background, the results showed variation in how goal orientations were associated with certain types of action-control beliefs.
Going Full Circle With Teacher Feedback

Research on the evaluation of early childhood programs focuses mainly on its outcomes rather than its process with often little attention given to the role that feedback to teachers in pre-kindergarten (pre-k) programs plays in the larger cycle of the evaluation process. This article provides a case example of a multiyear evaluation of community-based pre-k programs serving about 360 three- and four-year old children over a 5-year period in the District of Columbia. The Closing the Loop Evaluation Model proposed represents a responsive evaluation approach that illustrates the interconnected interactions between teacher feedback during the evaluation process and two supporting evaluation methodologies that emphasize social justice and utility. Findings from the case example highlight the responsive evaluation approach, feedback process, and ensuing conceptual and instrumental changes that occurred among stakeholders from whole-group feedback to small-group “report card” meetings with add-ons such as technical assistance, teacher-generated action plans, and teacher follow-up and feedback to close the evaluation loop. The authors discuss lessons learned about the evaluation process from the case example around aspects of feedback, including timing, audience, and function. Findings highlight the importance of feedback being timely and prompt, high quality in focus and content, non-punitive, collaborative, concise, and useful. The authors conclude that an evaluation process that includes teacher feedback, couched in social justice and utility, can have positive outcomes for all stakeholders and will likely lead to higher quality early childhood education programs.
The Effect of Rebalancing on the Performance of a Group Key Agreement Protocol

The most efficient contributory group key agreement protocols conduct their operations using a tree-based structure to guide communication and computation. Existing performance comparisons of group key protocols have only evaluated the cost of single operations in isolation. This paper expands this work by evaluating the performance impact of tree rebalancing operations on the overall cost of a group key agreement protocol over the course of the execution of several operations
Procedural Facilitation of Propositional Knowledge in the Content Areas

Both inclusion and challenging content area curricula require student proficiency in skills of learning. Strategy instruction that is supported with graphic procedural facilitators can help to meet that requirement, particularly for more complex, or higher order, tasks. Ninety-eight 8th graders with and without learning disabilities learned a higher order strategy for identifying, defending, and expressing factual and opinion knowledge. The strategy was taught across the curriculum using a graphic procedural facilitator. Student ability to generalize the skills was tested. Findings indicate both groups of students benefited to approximately equal levels. Those with weakest skill performance at pretest benefited the most.
Buddhism and decision making at individual, group and organizational levels

Purpose – The purpose of this paper is to explore how practical wisdom rooted in Buddhism can help modern managers make decisions in contemporary business organizations. Design/methodology/approach – The paper suggests a model explaining how individual level Buddhist beliefs in Dependent Origination are reflected in behavior of individual through mindfulness, compassion and expansion of self. The model also explores the consequences of above mentioned behavior in terms of individual, group and organizational level decision making, respectively. Findings – The paper develops propositions which demonstrate the possibility of applying the practical wisdom of Buddhism into the individual, group and organizational decision-making processes. The paper proposes an integrative model and suggests initiatives that can be taken in business organizations and business schools for applying the practical wisdom gleaned from the Buddhist traditions. Research limitations/implications – The paper brought the core concepts .
Scalable approximate query processing with the DBO engine

This article describes query processing in the DBO database system. Like other database systems designed for ad hoc analytic processing, DBO is able to compute the exact answers to queries over a large relational database in a scalable fashion. Unlike any other system designed for analytic processing, DBO can constantly maintain a guess as to the final answer to an aggregate query throughout execution, along with statistically meaningful bounds for the guess's accuracy. As DBO gathers more and more information, the guess gets more and more accurate, until it is 100% accurate as the query is completed. This allows users to stop the execution as soon as they are happy with the query accuracy, and thus encourages exploratory data analysis.
Listing All Maximal Cliques in Large Sparse Real-World Graphs

We implement a new algorithm for listing all maximal cliques in sparse graphs due to Eppstein, Loffler, and Strash (ISAAC 2010) and analyze its performance on a large corpus of real-world graphs. Our analysis shows that this algorithm is the first to offer a practical solution to listing all maximal cliques in large sparse graphs. All other theoretically-fast algorithms for sparse graphs have been shown to be significantly slower than the algorithm of Tomita et al. (Theoretical Computer Science, 2006) in practice. However, the algorithm of Tomita et al. uses an adjacency matrix, which requires too much space for large sparse graphs. Our new algorithm opens the door for fast analysis of large sparse graphs whose adjacency matrix will not fit into working memory.
Eradication by immunization with mycobacterial vaccines and tumor cells of microscopic metastases remaining after surgery.

Guinea pigs, each with a growing tumor from hepatoma cells implanted in the skin, were treated either by surgical excision alone of the dermal tumor or by surgery followed by administration of emulsified Bacillus Calmette-Guerin (BCG) cell walls alone or mixed with hepatoma cells. Animals treated by surgery alone developed malignant disease characterized by progressive lethal growth of lymph node metastasis. Injections of cell walls intradermally between the site of excision and the draining lymph node (regional injection) prevented the development of palpable metastasis in some animals; cell walls given intradermally on the side contralateral to the surgical site (remote injection) cured no animals. Similar treatments with preparations containing both cell walls and hepatoma cells prevented the development of malignant disease in a significant number of animals whether the injections were regional or remote. Treatment with mixtures consisting of living BCG and tumor cells was not as effective as treatment with cell walls mixed with tumor cells. A mixture consisting of modified BCG cell walls known as skeletons, trehalose dimycolate also known as cord factor or P3, and endotoxin was an effective substitute for BCG cell walls. There was no particular advantage in the use of the mixture containing BCG cell wall skeletons, trehalose dimycolate, and endotoxin instead of BCG cell walls. Neither preparation produced any gross systemic toxicity, and there was no statistical difference in their therapeutic efficacy. Undegraded cell wall emulsions were easier and less costly to prepare than was the three-component mixture. Animals treated by surgery followed by administration of BCG cell walls together with cells from another syngeneic hepatoma, immunologically distinct from the dermally implanted tumor, failed to eradicate microscopic lymph node metastases.
Treatment of stable delusional confabulations using self-monitoring training

In the present study Self-Monitoring Training (SMT) was utilised to treat a patient, WF, who had suffered subarachnoid haemorrhages after which he developed delusional confabulations which had remained stable for over 6 years. It was predicted that WF's dysexecutive difficulties would be associated with poor self-monitoring skills and SMT would result in a reduction in the expression of his delusional confabulations. Both predictions were confirmed and the improvement in WF's delusional confabulations was maintained at a 3-month follow up and found to generalise to everyday settings. These results suggest that SMT may be an efficacious treatment not only for behaviour problems following acquired brain injury but also for delusional confabulations. The possible mechanisms to account for these findings are discussed.
Data mining for analysing kiosk usage behavior patterns

This main purpose of this study is to understand the self-seeking behavior of participants in developed kiosks that provides interactive service at Huashan Creative Park in Taipei City. To understand user self-seeking patterns, log data from actual cases of interactive kiosk service were collected and analysed by web usage mining. This study analysed 5724 sessions of 8 kiosks for the month of December, 2013. Sequential profiles for user self-seeking behavior patterns were captured by applying sequence-based representation schemes in association with Markov models and enhanced K-mean clustering algorithms for sequence behavior mining cluster patterns. Self-seeking use cycle, time, function numbers, and the depth and extent (range) of services were statistically analysed. The analysis results can be used improved the public's acceptance of interactive kiosks and help generate potential recommendations for achieving an intelligent kiosk service.
Pharmacist prescribing practices in a clinical pharmacy cardiac risk service.

PURPOSE Prescribing practices within a clinical pharmacy cardiac risk service (CPCRS) and their impact on treatment outcomes in patients with atherosclerotic cardiovascular disease (ASCVD) are described. SUMMARY National healthcare reforms have increased the population of insured patients and placed increased demands on physicians and other providers. Pharmacists are well trained and positioned to aid in patient care by providing expertise in medication management and patient safety that can result in pharmacotherapy optimization and cost savings. Kaiser Permanente Colorado (KPCO), a group-model health maintenance organization with about 675,000 members served by 30 medical offices throughout Colorado, has adopted a collaborative drug therapy management (CDTM) model that enables pharmacist prescribing to improve patient access, patient care, and healthcare cost-effectiveness. Within the CPCRS established by KPCO, qualified pharmacists are permitted to prescribe initial therapy, modify drug regimens, order laboratory tests, and perform follow-up activities within their professional scope of practice. The CPCRS focuses on the long-term management of patients with ASCVD. The primary goals of the CPCRS are to optimize secondary-prevention pharmacotherapy, monitor and ensure medication adherence, assist in the management of risk factors for ASCVD, provide patient education and counseling, and serve as a resource for physicians and other healthcare providers. Working under a CDTM agreement, pharmacists are authorized to prescribe therapies to minimize the risk of future ASCVD events. CONCLUSION The CPCRS at KPCO has demonstrated successful maintenance of a clinical pharmacy service including pharmacist prescribing under a CDTM model to manage patients with ASCVD.