Miracle-dz/UniFAR-FTUs huggingface dataset:
A Brief History of 3 D Mesh Compression

3D graphics are evolving media type used in all aspects of technological areas of today. Increase in demand on 3D graphics pushes technological advancements on 3D scan technology and approximation methods to next level which then results in more complex and highly detailed large 3D raw data. Thus, it is crucial to compress these graphics data efficiently. Over the last two decades, many algorithms have been proposed to compress these raw 3D data especially for compact storage, fast transmission, and efficient processing. Compression methods are branching among themselves. In this paper, 3D compression methods are summarized in a taxonomical fashion. A special attention is paid to the main ideas behind the single-rate compression algorithms and their contribution to 3D mesh compression technology. The advantages and the drawbacks of each algorithm are discussed to pave the road for the future 3D compression researchers.
Classification methods for Cherenkov telescopes images on apixel-by-pixel base

The problem of identifying gamma ray events out of charged cosmic ray background (so called hadrons) in Cherenkov telescopes is one of the key problems in VHE gam ma ray astronomy. In this contribution, we present a novel approach to this problem by implementing different classifiers relying on the information of each pixel of the camera of a Cherenkov telescope, r ather than using common Hillas parameter analysis. Separation between gamma-like and hadron-like is p erformed using several machine learning techniques, trained using Monte Carlo data samples of both types o f events.
STUDENT FINAL GRADE PREDICTION BASED ON LINEAR REGRESSION

In the world of Massive Open Online Course (MOOC) and open education systems, students have flexibility to learn anything with ease as the learning content is easily available. But this facility can make student complacent. Therefore, it becomes difficult to predict student performance in advance. In this research an attempt is made to help the student to know his/her performance in advance by using univariate linear regression model. We collected the marks of internal exam components of one subject to predict the final grade in that subject. The internal marks are normalized to 100 (percentage) to have accurate results. The model provides predicted grade of final examination in particular subject. It also helps students to know how many marks in the internal examination are required to get particular grade.
An efficient fair UC-secure protocol for two-party computation

With the development of modern Internet and mobile networks, there is an increasing need for collaborative privacy-preserving applications. Secure multi-party computation SMPC gives a general solution to these applications and has become a hot topic. Yao's garbled circuit approach is a leading method in designing protocols for secure two-party computation 2PC, which is a very important base in SMPC. However, there are only few protocols obtaining the fairness of secure 2PC, and only one of them was constructed within the standard simulation framework but with very low efficiency. In this paper, we propose an efficient fair secure Yao's garbled circuit protocol within the universally composable UC framework. By comparing with all other fair secure Yao's protocols, our new protocol enjoys three advantages. First, our protocol is more efficient than any other fair secure Yao's protocols within the standard simulation framework. Second, our protocol is the first fair UC-secure Yao's garbled circuit protocol, so it is more secure than other fair Yao's protocols. Third, there does not require any third party involved in our protocol; thus, it is very suitable for many applications. Copyright © 2013 John Wiley & Sons, Ltd.
The Refractive Error of Professional Baseball Players.

PURPOSE High levels of visual acuity are required to hit a baseball effectively. Research has shown that any decrease in vision is likely caused by low-order optical aberrations. This study is designed to validate the SVOne autorefractor, and describe the amount and type, of low-order optical aberrations present in a large cohort of professional baseball players. METHODS A retrospective chart review on the 608 Major League Baseball players evaluated during the 2016 Spring Training Season was performed. Results for a subset of players who had both manifest refraction as well as autorefraction were calculated. Subsequently, after determining the accuracy of the autorefraction system in this population, refractive results for the entire population were determined. RESULTS There was a borderline statistically significant difference in mean spherical refractive error (M) between the manifest refraction and the SVOne auto refraction (-0.273D in the manifest refraction method vs. -0.503D in the SVOne method, P = .06) in the subset of athletes who underwent both tests. Additionally, there was no difference in the J0 or J45 cylindrical component vectors for each method. For the entire eligible population, the SVOne autorefraction system found a mean spherical refractive error (M) of -0.228D, a J0 value of -0.013D, and a J45 value of -0.040D. CONCLUSIONS These data suggest that the SVOne autorefraction system is generally able to measure the refractive error in the baseball population. The system was slightly biased, often reporting more myopia in myopic subjects. Thus, careful evaluation of the refractive status of these athletes coupled with careful subjective refractive correction for those with less than average vision for baseball is strongly suggested.
Android Malware Detection using Deep Belief Network

Over the last few years, the Android smartphone had faced attacks from malware and malware variants, as there is no effective commercial Android security framework in the market. Thus, using machine learning algorithms to detect Android malware applications that can fit with the smartphone resources limitations became popular. This paper used state of the art Deep Belief Network in Android malware detection. The Lasso is one of the best interpretable l1-regularisation techniques which proved to be an efficient feature selection embedded in learning algorithm. The selected features subset of Restricted Boltzmann Machines tuned by Harmony Search feature reduction with Deep Belief Network classifier was used, achieving 85.22% Android malware detection accuracy.
Activation of NG2-positive oligodendrocyte progenitor cells during post-ischemic reperfusion in the rat brain

This study examines the alteration of oligodendrocyte progenitor cells which express membrane NG2 chondroitin sulfate proteoglycan after focal ischemia in the rat brain. Adult male Sprague–Dawley rats were subjected to 90 min occlusion of the middle cerebral artery, followed by reperfusion time of up to 2 weeks. The distribution and morphological changes in NG2-positive oligodendrocyte progenitor cells were immunohistochemically examined. Stellate-shaped NG2-positive cells with multiple branched processes were detected in both the gray and white matter of normal brain. After 2 weeks of reperfusion, NG2-positive cells in the area surrounding the infarction site (peri-infarct area) clearly showed enlarged cell bodies with hypertrophied processes. These stained strongly for NG2. Although the number of NG2-positive cells was increased significantly in the peri-infarct area, it decreased markedly in the infarct core compared to controls. Double immunostaining revealed that these NG2-positive cells were neither astrocytes nor microglia, but NG2-positive oligodendrocyte progenitor cells. These progenitor cells are known to differentiate into oligodendrocytes. As such, this upregulation of NG2 expression may be an adaptive mechanism attempting to remyelinate rat brain tissue after ischemic insult. Only further study will elucidate this hypothesis.
A Pseudo Quantum Watermarking Algorithm in M-band Wavelet Domain

Computational methods derived from digital signal processing are playing a significant role in the security and copyrights of audio, video, and visual arts. In light of the quantum computing, the corresponding algorithms are becoming a new research direction in today’s high-technology world. The nature of quantum computer guarantees the security of quantum data, so a safe and effective quantum watermarking algorithm is in demand. Quantum watermarking is the technique that embeds the invisible quantum signal into quantum multimedia data for copyright protection. Different from most traditional algorithms, we propose new algorithms which apply a quantum or a pseudo quantum watermarking in M-band wavelet domain. Assured by the Heisenberg uncertainty principle and quantum no-cloning theorem, the security of quantum watermark can reach a very high-level standard. In other words, these watermarking algorithms can defeat nearly all attackers, no matter using classical computer or quantum computer. Keywords—Discrete M-band wavelet transforms (DMWT); Quantum and pseudo watermarks; Quantum computing; Quantum and pseudo Images.
New antagonists of LHRH. II. Inhibition and potentiation of LHRH by closely related analogues.

Modifications of the previously described LHRH antagonists, [Ac-D-Nal(2)1, D-Phe(4Cl)2, D-Trp3, D-Cit6, D-Ala10]LHRH and the corresponding D-Hci6 analogue, have been made to alter the hydrophobicity of the N-terminal acetyl-tripeptide portion. Substitution of D-Trp3 with the less hydrophobic D-Pal(3) had only marginal effects on the antagonistic activities and receptor binding potencies of the D-Cit/D-Hci6 analogues, but it appeared to further improve the toxicity lowering effect of D-Cit/D-Hci6 substitution. Antagonists containing D-Pal(3)3 and D-Cit/D-Hci6 residues, i.e. [Ac-D-Nal(2)1, D-Phe(4Cl)2, D-Pal(3)3, D-Cit6, D-Ala10]LHRH (SB-75) and [Ac-D-Nal(2)1, D-Phe(4Cl)2, D-Pal(3)3, D-Hci6, D-Ala10]LHRH (SB-88), were completely free of the toxic effects, such as cyanosis and respiratory depression leading to death, which have been observed in rats with the D-Trp3, D-Arg6 antagonist and related antagonists. Replacement of the N-acetyl group with the hydrophilic carbamoyl group caused a slight decrease in antagonistic activities, particularly in vitro. Introduction of urethane type acyl group such as methoxycarbonyl (Moc) or t-butoxycarbonyl (Boc) led to analogues that showed LHRH-potentiating effect. The increase in potency induced by these analogues, e.g. [Moc-D-Nal(2)1, D-Phe(4Cl)2, D-Trp3, D-Cit6, D-Ala10]LHRH and [Boc-D-Phe1, D-Phe(4Cl)2, D-Pal(3)3, D-Cit6, D-Ala10]LHRH, was 170-260% and persisted for more than 2 h when studied in a superfused rat pituitary system.
Pulmonary administration of vasoactive substances by perfluorochemical ventilation.

OBJECTIVES Therapeutic management of respiratory distress syndrome, pneumonia, and pulmonary hypertension includes delivery of biologically active agents to the neonatal lung. However, mechanical abnormalities of the lung, intrapulmonary shunting, ventilation-perfusion mismatching, and elevated surface tension impede effective systemic or intratracheal delivery of agents to the lung during conventional gas ventilation. The objective of this study was to test the hypothesis that perfluorochemical (PFC) liquid ventilation can be used for pulmonary administration of vasoactive drugs (PAD) and to compare these responses to those elicited with intravascular (IV) administration during tidal liquid ventilation. METHODS Cardiovascular responses of 16 preterm and neonatal lambs to randomized doses of acetylcholine, epinephrine, and priscoline were studied. Physiologic gas exchanged and acid-base balance were maintained using previously described tidal liquid ventilation techniques. In subgroups of animals, the distribution pattern of carbon 1- and choline 14-labeled dipalmitoylphosphatidylcholine (14C-DPPC) in saline and the responses to priscoline after hypoxia-induced pulmonary hypertension and hypoxemia administered during liquid ventilation were studied. RESULTS Dose-response curves for PAD and IV administration demonstrated progressive, dose-dependent, cholinergic responses to acetylcholine (decreased mean systemic arterial pressure [MAP] and heart rate), sympathomimetic responses to epinephrine (increased MAP and heart rate), and alpha-adrenergic blockade responses to priscoline (decreased MAP and mean pulmonary arterial pressure). Compared with IV administration, PAD of priscoline resulted in a significantly greater decrease in pulmonary relative to systemic arterial pressure; this response was potentiated by hypoxia, reduced pulmonary pressures to near normal values, and improved oxygenation. The 14C-DPPC in saline was distributed relatively homogeneously throughout the lung by PAD, with 80% of the lung pieces receiving amounts of 14C-DPPC with +/-20% of the mean value. CONCLUSIONS This study demonstrates that vasoactive agents can be delivered to the lung directly by PAD during PFC liquid ventilation. The inherent advantages of this method relate to the physical properties of PFC liquid ventilation as a vehicle (respiratory gas solubility, low surface tension-enhancing distribution, and inertness precluding interaction) and physiological properties of the lung as an exchanger.
Intravascular presence of tumor cells as prognostic parameter in uveal melanoma: a 35-year survey.

PURPOSE Invasion of tumor cells into blood vessels is essential for metastasis of uveal melanoma. The occurrence of ingrowth of tumor cells in blood vessels in uveal melanoma was analyzed, and this parameter was compared with the survival of the patients. METHODS Between 1972 and 2007, 643 eyes primarily enucleated for uveal melanoma were evaluated histopathologically. Survival data were obtained from charts and from the Integral Cancer Center patient registry. RESULTS No vascular ingrowth of tumor cells occurred in 59% of the eyes, whereas 18% had tumor cell ingrowth in vessels inside the tumor, 10% in vessels outside the tumor, and 8% in vessels inside as well as outside the tumor. The presence of any intravascular ingrowth of tumor cells correlated significantly with the diameter (P < 0.01) and prominence of the tumor (P < 0.01), as well as with non-spindle-cell type (P = 0.03) and intrascleral ingrowth (P < 0.01), and was associated with a worse survival. When extravascular matrix patterns were not included in the multivariate analysis, intravascular ingrowth came out as an independent prognostic factor, but this was not the case when extravascular matrix patterns were included in the multivariate model. CONCLUSIONS Intravascular ingrowth of tumor cells in uveal melanoma occurs frequently in combination with well-known histopathologic factors such as large tumor size, epithelioid cell type, and intrascleral ingrowth.
Dissimilatory nitrate reduction by Pseudomonas alcaliphila with an electrode as the sole electron donor

Denitrification and dissimilatory nitrate reduction to ammonium (DNRA) were considered two alternative pathways of dissimilatory nitrate reduction. In this study, we firstly reported that both denitrification and DNRA occurred in Pseudomonas alcaliphila strain MBR with an electrode as the sole electron donor in a double chamber bio‐electrochemical system (BES). The initial concentration of nitrate appeared as a factor determining the type of nitrate reduction with electrode as the sole electron donor at the same potential (−500 mV). As the initial concentration of nitrate increased, the fraction of nitrate reduced through denitrification also increased. While nitrite (1.38 ± 0.04 mM) was used as electron acceptor instead of nitrate, the electrons recovery via DNRA and denitrification were 43.06 ± 1.02% and 50.51 ± 1.37%, respectively. The electrochemical activities and surface topography of the working electrode catalyzed by strain MBR were evaluated by cyclic voltammetry and scanning electron microscopy. The results suggested that cells of strain MBR were adhered to the electrode, playing the role of electron transfer media for nitrate and nitrite reduction. Thus, for the first time, the results that DNRA and denitrification occurred simultaneously were confirmed by powering the strain with electricity. The study further expanded the range of metabolic reactions and had potential value for the recognization of dissimilatory nitrate reduction in various ecosystems. Biotechnol. Bioeng. 2012; 109: 2904–2910. © 2012 Wiley Periodicals, Inc.
Predictive factors for successful salvage high-dose therapy in patients with multiple myeloma relapsing after autologous blood stem cell transplantation

For patients with relapsed or refractory multiple myeloma (MM) treated with a prior high-dose therapy (HDT) followed by autologous peripheral blood stem cell transplantation (PBSCT), the reapplication of HDT is a widely used salvage strategy. In this retrospective study, we report on 55 patients who were treated with salvage HDT at our institution. The conditioning regimen consisted of melphalan 200 mg/m2 (27%), melphalan 140 mg/m2 and busulfan 12 mg/kg body weight (40%), or melphalan 200 mg/m2 and bortezomib 1.3 mg/m2 (33%). Treatment-related mortality was 5% and response rates were as follows: 9% complete remission, 9% very good partial remission, 56% partial remission, 11% minimal response + stable disease, and 4% progressive disease (5% not assessable). Toxicity was moderate and the median event-free (EFS) and overall survival (OS) were 14 months and 52 months, respectively. The different conditioning regimens did not result in differences in terms of remission rates, EFS and OS, or toxicity. In multivariate analysis a duration of remission of more than 12 months after the first transplant was the only predictive factor for both EFS (p < 0.0001) and OS (p = 0.0001). In conclusion, salvage HDT followed by autologous PBSCT is an effective treatment option for patients with relapsed or refractory MM, while patients with an early relapse after their first transplant do not benefit from this treatment modality.
A RANS-based Solution for Trailing-Edge Noise Including Adverse Pressure Gradient Effect

Trailing-edge noise is of great interest to many industries. It constitutes an important part of flow-induced noise, particularly for low Mach number flows. The turbulent flow over a hydro/airfoil and the associated sound generation is a complex phenomenon, particularly when flows are subjected to an Adverse Pressure Gradient (APG) that could be caused by an angle of attack (AOA) greater than zero. An APG can significantly change the flow characteristics and affect the sound generation. Trailing-edge noise can be predicted by either Computational Fluid Dynamics (CFD) or empirical models. Some effort in improving the existing empirical models for trailing-edge noise to account for APG influence can be found in the literature. A model based on CFD for calculating the surface pressure fluctuation and an acoustic analogy for sound radiation has been applied successfully to the attached flow. The ability of this model to predict the trailing edge noise for flows subject to an APG is addressed in this paper. In this paper, the trailing-edge noise from a 2D NACA0012 aerofoil at various Reynold numbers up to 6x10 and two angles of attack, 6.25o and 2.8o, are predicted using the RANS-based model previously developed for the attached flow. The predicted results are compared with experimental measurements. The calculated surface pressure spectra and radiated noise are in good agreement with the experimental data. It has found that the model previously developed for the attached flow can be directly applied to a flow subjected to an APG without modification.
Resistance Studies of a Dithiazol Analogue, DBPR110, as a Potential Hepatitis C Virus NS5A Inhibitor in Replicon Systems

ABSTRACT Hepatitis C virus (HCV), a member of the Flaviviridae family, affects approximately 3% of the world's population and is becoming the leading cause of liver disease in the world. Therefore, the development of novel or more effective treatment strategies to treat chronic HCV infection is urgently needed. In our previous study, we identified a potential HCV NS5A inhibitor, BP008. After further systemic optimization, we discovered a more potent HCV inhibitor, DBPR110. DBPR110 reduced the reporter expression of the HCV1b replicon with a 50% effective concentration (EC50) and a selective index value of 3.9 ± 0.9 pM and >12,800,000, respectively. DBPR110 reduced HCV2a replicon activity with an EC50 and a selective index value of 228.8 ± 98.4 pM and >173,130, respectively. Sequencing analyses of several individual clones derived from the DBPR110-resistant RNAs purified from cells harboring genotype 1b and 2a HCV replicons revealed that amino acid substitutions mainly within the N-terminal region (domain I) of NS5A were associated with decreased inhibitor susceptibility. P58L/T and Y93H/N in genotype 1b and T24A, P58L, and Y93H in the genotype 2a replicon were the key substitutions for resistance selection. In the 1b replicon, V153M, M202L, and M265V play a compensatory role in replication and drug resistance. Moreover, DBPR110 displayed synergistic effects with alpha interferon (IFN-α), an NS3 protease inhibitor, and an NS5B polymerase inhibitor. In summary, our results present an effective small-molecule inhibitor, DBPR110, that potentially targets HCV NS5A. DBPR110 could be part of a more effective therapeutic strategy for HCV in the future.
Regulation and Physiological Significance of ClpC and ClpP in Streptococcus mutans

ABSTRACT Tolerance of environmental stress, especially low pH, by Streptococcus mutans is central to the virulence of this organism. The Clp ATPases are implicated in the tolerance of, and regulation of the response to, stresses by virtue of their protein reactivation and remodeling activities and their capacity to target misfolded proteins for degradation by the ClpP peptidase. The purpose of this study was to dissect the role of selected clp genes in the stress responses of S. mutans, with a particular focus on acid tolerance and adaptation. Homologues of the clpB, clpC, clpE, clpL, clpX, and clpP genes were identified in the S. mutans genome. The expression of clpC and clpP, which were chosen as the focus of this study, was induced at low pH and at growth above 40°C. Inactivation of ctsR, the first of two genes in the clpC operon, demonstrated that CtsR acts as a repressor of clp and groES-EL gene expression. Strains lacking ClpP, but not strains lacking ClpC, were impaired in their ability to grow under stress-inducing conditions, formed long chains, aggregated in culture, had reduced genetic transformation efficiencies, and had a reduced capacity to form biofilms. Comparison of two-dimensional protein gels from wild-type cells and the ctsR and clpP mutants revealed many changes in the protein expression patterns. In particular, in the clpP mutant, there was an increased production of GroESL and DnaK, suggesting that cells were stressed, probably due to the accumulation of denatured proteins.
Antenna Requirements for Short Range High Speed Wireless Systems Operating at Millimeter-Wave Frequencies

Large amounts of worldwide unlicensed spectrum at 60 GHz may provide solutions for future short range very high speed wireless solutions. A number of challenges remain for this spectrum to be a viable solution for high volume consumer applications. In this paper, we look closely at requirements for antennas in indoor scattering environments with a focus on signal to noise ratio for fading multi-path channels. These requirements are compared with realistic received signal to noise ratios that can be expected with Si based RF front ends. This analysis shows that high gain adaptive antennas will be required to achieve acceptable performance. Though antennas do scale with frequency we show that they are still too large for easy integration into consumer electronics