Miracle-dz/UniFAR-FTUs huggingface dataset:
A Partial Retrieval of Music Data with Different Bit Rate using MPEG-4 TwinVQ Audio Compression

The present paper describes a method for partial retrieval of a piece of music using the autocorrelation coefficients computed in the encoding step of TwinVQ (Transform-domain Weighted Interleave Vector Quantization) audio compression (MPEG-4 audio standard). Our key contribution is to realize partial retrieval of a piece of music that is robust with respect to bit rate using an approximation relation. The approximation relation is based on the fact that the i-th autocorrelation coefficient with bit rate B1 of a piece of music computed in the encoding step of TwinVQ audio compression can approximate the j-th autocorrelation coefficient with bit rate B2 of the piece of music, where i = [(B1/B2) j]. First, we present our frame work for music information retrieval and music retrieval of a piece of music based on the autocorrelation coefficients computed in the encoding step of TwinVQ audio compression. Then, we show experimental results of partial retrieval of a piece of music on 1,023 pieces of music. The experimental results indicate that partial retrieval using the autocorrelation coefficients has excellent retrieval performance for queries of various bit rates.
Repeatability of Blood Gas Parameters, Pco2 Gap, and Pco2 Gap to Arterial-to-Venous Oxygen Content Difference in Critically Ill Adult Patients

AbstractThe objective of this study was to examine the repeatability of blood gas (BG) parameters and their derived variables such as the central venous-to-arterial carbon dioxide tension difference (▵PCO2) and the ratio of ▵PCO2 over the central arteriovenous oxygen content difference (▵PCO2/C(a-cv)O2) and to determine the smallest detectable changes in individual patients.A total of 192 patients with arterial and central venous catheters were included prospectively. Two subsequent arterial and central venous blood samples were collected immediately one after the other and analyzed using the same point-of-care BG analyzer. The samples were analyzed for arterial and venous BG parameters, ▵PCO2, and ▵PCO2/C(a-cv)O2 ratio. Repeatability was expressed as the smallest detectable difference (SDD) and the least significant change (LSC). A change in value of these parameters exceeding the SDD or the LSC should be regarded as real.The SDDs for arterial carbon dioxide tension, arterial oxygen saturation, central venous oxygen saturation (ScvO2), and ▵PCO2 were small: ±2.06 mm Hg, ±1.23%, 2.92%, and ±1.98 mm Hg, respectively, whereas the SDDs for arterial oxygen tension (PaO2) and ▵PCO2/C(a-cv)O2 were high: ±9.09 mm Hg and ±0.57 mm Hg/mL, respectively. The LSCs (%) for these variables were 5.06, 1.27, 4.44, 32.4, 9.51, and 38.5, respectively.The repeatability of all these variables was good except for PaO2 and ▵PCO2/C(a-cv)O2 ratio for which we observed an important inherent variability. Expressed as SDD, a ScvO2 change value of at least ±3% should be considered as true. The clinician must be aware that an apparent change in these variables in an individual patient might represent only an inherent variation.
Assessments of Maleo Macrocephalon maleo nesting grounds in South-east Sulawesi reveal severely threatened populations

Summary The Maleo Macrocephalon Maleo is a megapode bird endemic to Sulawesi, Indonesia, that lays large eggs at communal nesting grounds in naturally-heated sands or soils. It is classified as ‘Endangered’ and many populations have been extirpated due to overexploitation of eggs and loss of connectivity between forest and nesting grounds. The distribution and status of nesting grounds across Northern and Central Sulawesi are relatively well-established, but almost nothing is known about potential Maleo populations of South-east Sulawesi. In this study we used previously established methods to formally assess the status of three Maleo nesting grounds in Buton, South-east Sulawesi, and interviewed egg collectors at these three sites to determine the trends of populations and threats over time. All nesting grounds were severely threatened and can be expected to be abandoned in the near future due to extensive harvest of eggs and deforestation. Eggs were collected both for the wildlife trade (intensively harvested and sold as luxury items to people from distant cities) and local use (opportunistically harvested and both eaten and sold locally). All egg collectors remarked on an increase in illegal logging around nesting grounds over the previous decade. Though the Maleo’s current situation is dire, previous case studies show that collaborative grassroots initiatives supported by government and NGOs can protect nesting grounds and reverse population declines.
The Design, Control, and Testing of an Integrated Electrohydrostatic Powered Ankle Prosthesis

This paper presents a prototype powered ankle prosthesis that can operate passively in most of the gait cycle and provide powered assistance for toe push-off and subsequent foot dorsiflexion. The use of an electrohydrostatic actuator (EHA) gives the ability to switch quickly and smoothly between passive and active modes. In this new powered ankle prosthesis, the motor–pump unit is integrated with the ankle joint and the battery and controller are held in a backpack. A 100 W brushless dc motor is used to drive a 0.45 cc/rev gear pump, controlling flow to an ankle cylinder through a bespoke manifold. The motor runs wet, pressurized to 6 MPa, avoiding the need for a pump shaft seal and a refeeding circuit for external leakage. A dynamic system model has been develop to help analyze the EHA performance. A motor control method is proposed based on heel strike recognition and a middle stance time delay. The prosthesis has been tested with a 70 kg transtibial amputee, and results are presented for walking on a treadmill at three different speeds (2.8, 3.8, and 4.8 km/h). The amputee has provided positive subjective feedback. We conclude that the hybrid passive–active approach has significant advantages for prosthesis design, and we outline future testing and development requirements.
Bartonella spp. in Bats, Kenya

We report the presence and diversity of Bartonella spp. in bats of 13 insectivorous and frugivorous species collected from various locations across Kenya. Bartonella isolates were obtained from 23 Eidolon helvum, 22 Rousettus aegyptiacus, 4 Coleura afra, 7 Triaenops persicus, 1 Hipposideros commersoni, and 49 Miniopterus spp. bats. Sequence analysis of the citrate synthase gene from the obtained isolates showed a wide assortment of Bartonella strains. Phylogenetically, isolates clustered in specific host bat species. All isolates from R. aegyptiacus, C. afra, and T. persicus bats clustered in separate monophyletic groups. In contrast, E. helvum and Miniopterus spp. bats harbored strains that clustered in several groups. Further investigation is needed to determine whether these agents are responsible for human illnesses in the region.
Cross-Modal Integration of Reward Value during Oculomotor Planning

Abstract Reward value guides goal-directed behavior and modulates early sensory processing. Rewarding stimuli are often multisensory, but it is not known how reward value is combined across sensory modalities. Here we show that the integration of reward value critically depends on whether the distinct sensory inputs are perceived to emanate from the same multisensory object. We systematically manipulated the congruency in monetary reward values and the relative spatial positions of co-occurring auditory and visual stimuli that served as bimodal distractors during an oculomotor task performed by healthy human participants (male and female). The amount of interference induced by the distractors was used as an indicator of their perceptual salience. Our results across two experiments show that when reward value is linked to each modality separately, the value congruence between vision and audition determines the combined salience of the bimodal distractors. However, the reward value of vision wins over the value of audition if the two modalities are perceived to convey conflicting information regarding the spatial position of the bimodal distractors. These results show that in a task that highly relies on the processing of visual spatial information, the reward values from multiple sensory modalities are integrated with each other, each with their respective weights. This weighting depends on the strength of prior beliefs regarding a common source for incoming unisensory signals based on their congruency in reward value and perceived spatial alignment.
Task demand modulation of steady‐state functional connectivity to primary motor cortex

Correlations in blood oxygen level‐dependent (BOLD) MRI signals from separate areas within the human brain have been used as a measure of functional connectivity. Steady‐state measures of interregional correlations are particularly useful because they do not depend on the specific design of a task nor on subtracting conditions in a blocked design task. However, the conditions under which such correlations are measured may influence these indices of functional connectivity. The aim of this study was to investigate the influence of task demand on interregional correlations within the motor system. Specifically, tapping rates in audibly paced finger‐tapping tasks were controlled and varied between runs in order to observe their effects on interregional correlations to contralateral primary motor cortex (PM). Regions of interest included the supplementary motor area, ipsilateral cerebellum, ipsilateral auditory cortex, and a control region. It was found that tapping rate was a significant factor in determining the mean correlation of some regions to PM, and that correlations measured during tapping in general increased relative to resting state. Furthermore, analysis of the percent of voxels in each region significantly correlated to PM suggested that changes in the mean correlation of that region to PM could be accounted for by changes in the fraction of significantly correlated voxels within a region. This provides insight into the manner in which steady‐state correlations are modified in response to different task demands and further evidence that low‐frequency fluctuations in BOLD signals reflect functional connectivity. Hum Brain Mapp, 2006. © 2006 Wiley‐Liss, Inc.
Visualisation and Exploration of High-Dimensional Distributional Features in Lexical Semantic Classification

Vector space models and distributional information are widely used in NLP. The models typically rely on complex, high-dimensional objects. We present an interactive visualisation tool to explore salient lexical-semantic features of high-dimensional word objects and word similarities. Most visualisation tools provide only one low-dimensional map of the underlying data, so they are not capable of retaining the local and the global structure. We overcome this limitation by providing an additional trust-view to obtain a more realistic picture of the actual object distances. Additional tool options include the reference to a gold standard classification, the reference to a cluster analysis as well as listing the most salient (common) features for a selected subset of the words.
The Effects of Progesterone on Oocyte Maturation and Embryo Development

Oocyte maturation and embryo development are controlled by intra-ovarian factors such as steroid hormones. Progesterone (P4) exists in the follicular fluid that contributes to normal mammalian ovarian function and has several critical functions during embryo development and implantation, including endometrial receptivity, embryonic survival during gestation and transformation of the endometrial stromal cells to decidual cells. It is well known that the physiological effects of P4 during the pre-implantation stages of some mammal’s embryos are mediated by P4 receptors and their gene expression is determined. The effects of P4 on oocytes and embryo development have been assessed by some investigations, with contradictory results. P4, a dominant steroid in follicular fluid at approximately 18 hours after the luteinizing hormone (LH ) surge may have a critical role in maturation of oocytes at the germinal stage. However, it has been shown that different concentrations of P4 could not improve in vitro maturation rates of germinal vesicles (GV) in cumulus oocyte complexes (COCs) and cumulus denuded oocytes (CDOs). Culture media supplemented with P4 significantly improved mouse embryo development. In addition, an in vivo experimental design has shown high blastocyst survival and implantation rates in P4-treated mice. In this review we explain some of the findings that pertain to the effects of P4 on oocyte maturation and embryo development both in vitro and in vivo.
Glucose Metabolism in 105 Children and Adolescents After Pancreatectomy for Congenital Hyperinsulinism

OBJECTIVE To describe the long-term metabolic outcome of children with congenital hyperinsulinism after near-total or partial elective pancreatectomy. RESEARCH DESIGN AND METHODS Patients (n = 105: 58 diffuse and 47 focal congenital hyperinsulinism) received operations between 1984 and 2006. Follow-up consisted of periodic measurements of pre- and postprandial plasma glucose over 24 h, OGTT, and IVGTT. Cumulative incidence of hypo- or hyperglycemia/insulin treatment was estimated by Kaplan-Meier analysis. RESULTS After near-total pancreatectomy, 59% of children with diffuse congenital hyperinsulinism still presented mild or asymptomatic hypoglycemia that responded to medical treatments and disappeared within 5 years. One-third of the patients had both preprandial hypoglycemia and postprandial hyperglycemia. Hyperglycemia was found in 53% of the patients immediately after surgery; its incidence increased regularly to 100% at 13 years. The cumulative incidence of insulin-treated patients was 42% at 8 years and reached 91% at 14 years, but the progression to insulin dependence was very variable among the patients. Plasma insulin responses to IVGTT and OGTT correlated well with glycemic alterations. In focal congenital hyperinsulinism, hypoglycemia or hyperglycemia were rare, mild, and transient. CONCLUSIONS Patients with focal congenital hyperinsulinism are cured of hypoglycemia after limited surgery, while the outcome of diffuse congenital hyperinsulinism is very variable after near-total pancreatectomy. The incidence of insulin-dependent diabetes is very high in early adolescence.
Energy Efficient Method in Fault Node Recovery for A Wireless Sensor Network

In Wireless Sensor Network, the sensor nodes forms a cluster and each cluster will have a cluster head. The cluster head is selected on the basis of battery level. The cluster head collect the data from the sensors and transmit the data to the sink node. Since the cluster head is transmitting more amount of data compare with other nodes, so it will drains the battery. Due to this the cluster head is losing the energy very fastly and shuts down. The battery drained cluster head is known as sensor fault. The sensor fault will leads to data loss. So, the sensor fault is re placed by using FNR algorithm. Even though, the sensor faults has been replaced; the cluster head have to transmit more data and loses its energy. To minimize the risk of sensor faults, an efficient method is used to compress the data.
System level design of Bluetooth front end using novel low IF topology

In the last few year architectures based on low IF/zero IF have been proposed and investigated. The low IF/zero IF receivers are alternatives to the classical superheterodyne receiver in terms of cost and integration. In this paper the system level simulation of novel Low IF receiver has been investigated for Bluetooth front end design. The receiver uses a dual IF architecture to cover the ISM band 2.400-2.485 GHz. The designed front end has been implemented in ADS, key performance value meet the bluetooth requirement. With the RF input signal of center frequency 2.44 GHz, the novel low IF front end architecture exhibits 55.46 dB front end gain, 8.341 dB Noise Figure, 0 dBm IIP3 and Image rejection of 56.23 dB.
Stabilization of energy charge, generation of oscillations and multiple steady states in energy metabolism as a result of purely stoichiometric regulation.

A simple kinetic model of cell energy metabolism with autocatalytic reaction sequences has beepn analysed. The model accounts for the fact that part of energy produced in the form of ATP, or any other equivalent form, is utilized in "sparking" reactions to activate initial substrates. Analysis of the model shows that energy metabolism, in the absen-e of all non-stoichiometric (i.e. isosteric, cooperative, and allosteric) regulations, is capable of (a) stabilizing, to a high degree of accuracy, the relative concentration of the "charged form" of the energy-transferring cofactor (ATP); (b) alternating between two stable stationary states by means of hysteretic transitions; (c) generating self-oscillations in energy production. It is proposed that energy metabolism can be a source of very slow, in particular circadian (of about a one-day period), oscillations which may serve as the basis for temporal organization of the cell.
Micturition Problems After Bladder Distension During Hospitalization in Sweden: “I’m Not Ill, Just Damaged for the Rest of My Life”

BackgroundUrinary retention is a common complication following hospital care, which can result in overdistension of the bladder and, at worst, chronic bladder damage and persistent micturition difficulties. ObjectivesThe purpose of this study was to explore patients’ experiences of micturition problems after bladder distension and their effects on the patients’ everyday lives. MethodsThe Swedish Patient Insurance LÖF was used to identify patients from January 2007 to June 2010 who have reported micturition problems after hospital care and have had their injuries classified as avoidable bladder damage due to overdistension. Narrative interviews were conducted with 20 volunteers and analyzed by qualitative content analysis. ResultsThe micturition problems affected everyday life through constraints (dependence on disposables and access to toilets, clothing restrictions, limitations on social life and career), suffering (pain, infections, impaired sex life, leakage), and concerns for the future (fear of worsening symptoms and fear of losing control with age). Aspects related to having been harmed by the healthcare system were the harm could have been avoided (lack of knowledge, insufficient routines, mistrust), obstacles to overcome when reporting an injury (difficulties in obtaining knowledge about the possibility of reporting an injury, ambivalence toward reporting their healthcare providers), and a wish to improve care (raise awareness, prevent harm to others). DiscussionBladder distension is a healthcare-related injury that can cause suffering and practical, emotional, and psychosocial problems with a great impact on the life of the person affected and anxiety for the future. The healthcare system must, therefore, raise awareness and improve preventive routines.
Searching for Interacting Features

Feature interaction presents a challenge to feature selection for classification. A feature by itself may have little correlation with the target concept, but when it is combined with some other features, they can be strongly correlated with the target concept. Unintentional removal of these features can result in poor classification performance. Handling feature interaction can be computationally intractable. Recognizing the presence of feature interaction, we propose to efficiently handle feature interaction to achieve efficient feature selection and present extensive experimental results of evaluation.
Concerns, coping and the electronic Holistic Needs Assessment: experiences of UK breast cancer survivors

Background Physical and psychological concerns associated with a breast cancer diagnosis continue long after treatment. Macmillan Cancer Support developed an electronic Holistic Needs Assessment (eHNA) to help identify these concerns and allow a healthcare professional to address these as part of The Recovery Package. Aims The study aim was to understand the women’s experiences of having breast cancer, and of completing Macmillan’s eHNA as part of their care. Methods A qualitative approach was adopted. Semi-structured interviews were undertaken with 15 women, 12–18 months following surgical treatment for invasive breast cancer. Thematic analysis identified key themes. Results Four main themes were identified in relation to experiences of the eHNA, experiences of breast cancer, coping with breast cancer and the psychological effects of surviving. Perceptions towards the eHNA varied; some women viewed the eHNA as a research tool for hospital use rather than a beneficial aspect of their care. Several participants felt unable to raise their psychological concerns on the eHNA. Conclusions Although experiences differ, psychological issues remain a key factor for women with breast cancer, lasting long after treatment. The eHNA is not currently used to its potential or recognised by women as a tool to support their care. Further research is needed into how the eHNA can be used effectively to capture psychological concerns and determine best approaches to implementation of the tool to support individualised care.
Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.

BACKGROUND Bapineuzumab, a humanized anti-amyloid-beta monoclonal antibody, is in clinical development for the treatment of Alzheimer's disease. METHODS We conducted two double-blind, randomized, placebo-controlled, phase 3 trials involving patients with mild-to-moderate Alzheimer's disease--one involving 1121 carriers of the apolipoprotein E (APOE) ε4 allele and the other involving 1331 noncarriers. Bapineuzumab or placebo, with doses varying by study, was administered by intravenous infusion every 13 weeks for 78 weeks. The primary outcome measures were scores on the 11-item cognitive subscale of the Alzheimer's Disease Assessment Scale (ADAS-cog11, with scores ranging from 0 to 70 and higher scores indicating greater impairment) and the Disability Assessment for Dementia (DAD, with scores ranging from 0 to 100 and higher scores indicating less impairment). A total of 1090 carriers and 1114 noncarriers were included in the efficacy analysis. Secondary outcome measures included findings on positron-emission tomographic amyloid imaging with the use of Pittsburgh compound B (PIB-PET) and cerebrospinal fluid phosphorylated tau (phospho-tau) concentrations. RESULTS There were no significant between-group differences in the primary outcomes. At week 78, the between-group differences in the change from baseline in the ADAS-cog11 and DAD scores (bapineuzumab group minus placebo group) were -0.2 (P=0.80) and -1.2 (P=0.34), respectively, in the carrier study; the corresponding differences in the noncarrier study were -0.3 (P=0.64) and 2.8 (P=0.07) with the 0.5-mg-per-kilogram dose of bapineuzumab and 0.4 (P=0.62) and 0.9 (P=0.55) with the 1.0-mg-per-kilogram dose. The major safety finding was amyloid-related imaging abnormalities with edema among patients receiving bapineuzumab, which increased with bapineuzumab dose and APOE ε4 allele number and which led to discontinuation of the 2.0-mg-per-kilogram dose. Between-group differences were observed with respect to PIB-PET and cerebrospinal fluid phospho-tau concentrations in APOE ε4 allele carriers but not in noncarriers. CONCLUSIONS Bapineuzumab did not improve clinical outcomes in patients with Alzheimer's disease, despite treatment differences in biomarkers observed in APOE ε4 carriers. (Funded by Janssen Alzheimer Immunotherapy and Pfizer; Bapineuzumab 301 and 302 ClinicalTrials.gov numbers, NCT00575055 and NCT00574132, and EudraCT number, 2009-012748-17.).