Miracle-dz/UniFAR-FTUs huggingface dataset:
Understanding Local Policy Elites’ Perceptions on the Benefits and Risks Associated with High‐Voltage Power Line Installations in the State of Arkansas

Recently, a controversial policy debate has arisen concerning the installation of high‐voltage power lines in northwest Arkansas. While proponents argue that such an installation is inevitable to efficiently and reliably support the identified electric load in the region, opponents claim that the lines will degrade the natural environment and hamper the tourism‐based local economy in affected regions, notably in Ozark Mountain areas. Of particular interest is to understand how local policy elites perceive the benefits and risks associated with such divisive proposals, which is critical for comprehending the formation and changes of related government policies. Based upon the dual process theory of judgment, this study systematically investigates the triadic relationships between (a) more profound personal value predispositions, (b) affects and feelings, and (c) perceived benefits and risks related to the proposed installation of high‐voltage power lines among local policy elites in the state of Arkansas. In doing so, we analyze original data collected from a statewide Internet survey of 420 local leaders and key policymakers about their opinions on the related issues, while considering other factors claimed by previous literature to influence risk perceptions, including trust, knowledge level, and demographic characteristics. Analytical results suggest that grid‐group cultural predispositions, as deeply held core values within local policy elites’ individual belief systems, both directly and indirectly—through affective feelings—shape perceived utility associated with the installation of high‐voltage power lines. We conclude this article by suggesting some practical considerations for better designing policy addressing controversial issues of this nature.
Practical Anonymous Subscription with Revocation Based on Broadcast Encryption

In this paper we consider the problem where a client wishes to subscribe to some product or service provided by a server, but maintain their anonymity. At the same time, the server must be able to authenticate the client as a genuine user and be able to discontinue (or revoke) the client’s access if the subscription fees are not paid. Current solutions for this problem are typically constructed using some combination of blind signature or zero-knowledge proof techniques, which do not directly support client revocation (that is, revoking a user before expiry of their secret value). In this paper, we present a solution for this problem on the basis of the broadcast encryption scheme, suggested by Boneh et al., by which the server can broadcast a secret to a group of legitimate clients. Our solution allows the registered client to log into the server anonymously and also supports client revocation by the server. Our solution can be used in many applications, such as location-based queries. We formally define a model for our anonymous subscription protocol and prove the security of our solution under this model. In addition, we present experimental results from an implementation of our protocol. These experimental results demonstrate that our protocol is practical.
Globalisierung in der Wirtschaftskrise: wie sicher sind die Jobs in Deutschland?

Die globale Wirtschaftskrise hinterlasst ihre Spuren zunehmend auch auf den internationalen Arbeitsmarkten. Angesichts dramatischer Nachfrageeinbruche auf den globalen Markten fur Guter und Dienstleistungen stehen Produktionskapazitaten und damit die Beschaftigung in den meisten Unternehmen auf dem Prufstand. Im gunstigsten Fall konnen gut aufgestellte, international wettbewerbsfahige Unternehmen ein konjunkturelles Zwischentief auf ihren Markten ohne nachhaltige Schaden uberstehen: Sie sichern erst einmal mit Uberbruckungsmasnahmen wie dem Abbau von Arbeitszeitkonten, der Reduzierung von Zeitarbeit oder der Nutzung arbeitsmarktpolitischer Instrumente, insbesondere der Kurzarbeit, den Unternehmensbestand und damit den Kern der Arbeitsplatze. Denn die Stammbelegschaften stellen ein wertvolles Unternehmenskapital dar, das in der kommenden Aufschwungphase gebraucht wird. Im Fall einer langeren Abschwungphase kann allerdings trotzdem eine Neubewertung der Unternehmensstrukturen notwendig werden und ein Beschaftigungsabbau die Folge sein.
An open‐label, pilot study evaluating the safety and efficacy of converting from calcineurin inhibitors to sirolimus in established renal allograft recipients with moderate renal insufficiency

Abstract: This pilot study was designed to evaluate the safety and efficacy of converting from a calcineurin inhibitor (CI) to a sirolimus (SRL)‐based regimen in established renal transplant recipients with moderate renal insufficiency. Sixty renal transplant recipients on CI‐based immuno‐suppression with a serum creatinine (SCr) between 159 and 265 μM (1.8 and 3.0 mg/dL) and a glomerular filtration rate (GFR) between 30 and 70 mL/min were enrolled. SRL dosing was dependent upon concomitant immunosuppressive therapy. The mean patient age was 45 yr and the mean time from transplant to study enrollment was 60.8 months (range: 7–198). The median SCr was 168 μM (1.9 mg/dL) and the median GFR was 51 mL/min. Twelve months after conversion the patient and graft survival rates were 96.7% and 95%, respectively. The incidence of biopsy‐proven acute rejection was 3.3% (two cases reported, Banff grades IA and IB). The median SCr and median creatinine clearance were 168 μM (1.9 mg/dL) and 53 mL/min, respectively. Hyperlipidemia, diarrhea, peripheral edema, rash, and anemia were the most commonly reported adverse events. Patients with moderate renal insufficiency can be converted from CI to SRL‐based therapy and maintain renal function over a 1‐yr period.
Sentiment Analysis Tool using Machine Learning Algorithms

As the increase of social networking, people started to share information through different kinds of social media. Among all varieties of social media, Twitter is a valuable resource for data mining because of its prevalence and recognition by famous persons. In this paper we present a system which collects Tweets from social networking sites, we'll be able to do analysis on those Tweets and thus provide some prediction of business intelligence. Results of trend analysis will be display as tweets with different sections presenting positive, Negative and neutral.
Das IÖW/future-Ranking der Nachhaltigkeitsberichte

Alle zwei Jahre bewerten das Institut fur okologische Wirtschaftsforschung und die Unternehmerinitiative „future – verantwortung unternehmen“ die Nachhaltigkeitsberichterstattung deutscher Unternehmen. Im achten IOW/future-Ranking wurden Ende Februar die Preistrager gekurt.
Network community detection using modularity density measures

Modularity, since its introduction, has remained one of the most widely used metrics to assess the quality of community structure in a complex network. However the resolution limit problem associated with modularity limits its applicability to networks with community sizes smaller than a certain scale. In the past various attempts have been made to solve this problem. More recently a new metric, modularity density, was introduced for the quality of community structure in networks in order to solve some of the known problems with modularity, particularly the resolution limit problem. Modularity density resolves some communities which are otherwise undetectable using modularity. However, we find that it does not solve the resolution limit problem completely by investigating some cases where it fails to detect expected community structures. To address this problem, we introduce a variant of this metric and show that it further reduces the resolution limit problem, effectively eliminating the problem in a wide range of networks.
Structure of HI1333 (YhbY), a putative RNA‐binding protein from Haemophilus influenzae

Mark A. Willis, Wojciech Krajewski, Vani Rao Chalamasetty, Prasad Reddy, Andrew Howard, and Osnat Herzberg* Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, Rockville, Maryland The National Institute of Standards and Technology, Gaithersburg, Maryland Advanced Photon Source, Argonne National Laboratory, Argonne, Illinois Illinois Institute of Technology, Chicago, Illinois
Centromeric DNA destabilizes H3 nucleosomes to promote CENP-A deposition during the cell cycle

Active centromeres are defined by the presence of nucleosomes containing CENP-A, a histone H3 variant, which alone is sufficient to direct kinetochore assembly. Once assembled at a location CENP-A chromatin and kinetochores are maintained at that location though a positive feedback loop where kinetochore proteins recruited by CENP-A itself promote deposition of new CENP-A following replication. Although CENP-A chromatin itself is a heritable entity, it is normally associated with specific sequences. Intrinsic properties of centromeric DNA may favour the assembly of CENP-A rather than H3 nucleosomes. Here we investigate histone dynamics on centromeric DNA. We show that during S-phase histone H3 is deposited as a placeholder at fission yeast centromeres and is subsequently evicted in G2 when we detect deposition of the majority of new CENP-ACnp1. We also find that centromeric DNA has an innate property of driving high rates of turnover of H3 containing nucleosomes resulting in low nucleosome occupancy. When placed at an ectopic chromosomal location in the absence of any CENP-ACnp1 assembly, centromeric DNA retains its ability to impose S-phase deposition and G2 eviction of H3, suggesting that features within this DNA program H3 dynamics. As RNAPII occupancy on this centromere DNA coincides with H3 eviction in G2, we propose a model in which RNAPII-coupled chromatin remodelling promotes replacement of H3 with CENP-ACnp1 nucleosomes.
Application of Continuous-Wave Cavity Ring-Down Spectroscopy to Laminar Flames

In this paper, we describe the application of diode-laser continuous-wave cavity ring-down spectroscopy (cw-CRDS) to in-situ flame diagnostics. Spectra of the P17e acetylene feature at 1535.4 nm were recorded in a premixed laminar ethylene/air flame. The overall absorption of the feature was measured to be ≈1.5 × 10-4 cm-1, which is a short distance above the reaction zone for a flame fuel equivalence ratio of 1.66, and the minimum detection limit (3σ) of the system was calculated to be 1.2 × 10-5 cm-1. This demonstrates the potential of the technique for the measurement of weakly absorbing species in flames. Finally, we discuss the advantages and limitations of the cw-CRDS technique for flame measurements.
The study of the rough medium surface by improved IPO

Iterative physical optics (IPO) is one of the important methods in the study of electromagnetic scattering. In this paper, the formula of IPO based on PO is derived. Based on the formula, the bistatic scattering and back scattering of dielectric sea surface with different incident angles are calculated, and the calculation results are compared with the FEKO built-in numerical algorithm for multilayer fast multipole (MLFMM) method and physical optics (PO). In order to improve the operation efficiency, a kind of the CPU parallel acceleration, OpenMP technology, is introduced, which effectively reduces the time consumption of the iterative process.
A New Drug Combinatory Effect Prediction Algorithm on the Cancer Cell Based on Gene Expression and Dose–Response Curve

Gene expression data before and after treatment with an individual drug and the IC20 of dose–response data were utilized to predict two drugs' interaction effects on a diffuse large B‐cell lymphoma (DLBCL) cancer cell. A novel drug interaction scoring algorithm was developed to account for either synergistic or antagonistic effects between drug combinations. Different core gene selection schemes were investigated, which included the whole gene set, the drug‐sensitive gene set, the drug‐sensitive minus drug‐resistant gene set, and the known drug target gene set. The prediction scores were compared with the observed drug interaction data at 6, 12, and 24 hours with a probability concordance (PC) index. The test result shows the concordance between observed and predicted drug interaction ranking reaches a PC index of 0.605. The scoring reliability and efficiency was further confirmed in five drug interaction studies published in the GEO database.
Effects of Nursing Interventions Planned with the Health Promotion Models on the Breast and Cervical Cancer Early Detection Behaviors of the Women

Background: Breast cancer and cervical cancer are important co mmunity health problems and the chance of surviving increases when diagnosed early. Objective: The study was conducted to ensure them to perfor m the breast and cervical cancer early detection behaviors of women over age 40. Methods: Research sample was composed of 100 women, 50 of w hom constituted the experiment group and 50 of whom constituted the control group. It is an qua si-experimental study. In the collection of the dat a, Information Forms related to the Socio-Demographica l attributes and the Previous Behaviors, Health Bel ief Model Scale, Self-Efficacy Scale and the Healthy Li festyle Behaviors Scale II-Health Responsibility Su bscale were used. Results: At the end of the nursing interventions performed by using the health promotion models, it was found that rates and perceptions of the women concerning the breast and cervical cancer early detection beha viors were higher in the experiment group when compared to the control group. Besides, a significant decrease was detected in the inhibiting factors perception of the experim ent group. Conclusions: Positive changes observed in the breast and cervic al cancer early detection behaviors of the women as a result of the nursing interventions show the efficiency of the nursing interventions based on the Health Belief Model and the Health Promotion Model. Spreading these interventions to the national leve l is of importance in maintaining the continuity of the pos itive changes.
Pyrido[3,4-d]pyrimidin-4(3H)-one metabolism mediated by aldehyde oxidase is blocked by C2-substitution

Abstract 1. We have previously described C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-one derivatives as cell permeable inhibitors of the KDM4 and KDM5 subfamilies of JmjC histone lysine demethylases. 2. Although exemplar compound 1 exhibited moderate clearance in mouse liver microsomes, it was highly cleared in vivo due to metabolism by aldehyde oxidase (AO). Similar human and mouse AO-mediated metabolism was observed with the pyrido[3,4-d]pyrimidin-4(3H)-one scaffold and other C8-substituted derivatives. 3. We identified the C2-position as the oxidation site by LC-MS and 1H-NMR and showed that C2-substituted derivatives are no longer AO substrates. 4. In addition to the experimental data, these observations are supported by molecular modelling studies in the human AO protein crystal structure.
Plaquette ordered phase and quantum spin liquid in the spin-1/2 J1-J2 square Heisenberg model

We study the spin -1/2 Heisenberg model on the square lattice with first- and second-neighbor antiferromagnetic interactions J_1 and J_2, which possesses a nonmagnetic region that has been debated for many years and might realize the interesting Z_2 spin liquid (SL). We use the density matrix renormalization group approach with explicit implementation of SU(2) spin rotation symmetry and study the model accurately on open cylinders with different boundary conditions. With increasing J_2, we find a Neel phase, a plaquette valence-bond (PVB) phase with a finite spin gap, and a possible spin liquid in a small region of J_2 between these two phases. From the finite-size scaling of the magnetic order parameter, we estimate that the N´eel order vanishes at J_2/J_1≃0.44. For 0.5 < J_2/J_1 < 0.61, we find dimer correlations and PVB textures whose decay lengths grow strongly with increasing system width, consistent with a long-range PVB order in the two-dimensional limit. The dimer-dimer correlations reveal the s-wave character of the PVB order. For 0.44 < J_2/J_1 < 0:5, both spin order, dimer order, and spin gap are small on finite-size systems and appear to scale to zero with increasing system width, which is consistent with a possible gapless SL or a near-critical behavior. We compare and contrast our results with earlier numerical studies.
Combining recursive Retinex and eye adaptation for high dynamic range compression

A novel adaptation-based recursive Retinex algorithm is proposed in this paper. The recursive scheme works in a similar way to the first recursive Retinex algorithm proposed by Frankle and McCann. Simulating the spatial response of retinal photoreceptors, the pixel level adaptation is implemented instead of the ratio-product operations. Thus the dynamic range is compressed efficiently without altering the spatial properties of the original image. In addition, the iteration proceeds in a simultaneous manner, thus the spatial distortion over directions is eliminated. Moreover, the sensitivity constant can be tuned for different strength of local contrast enhancement. Finally, global dynamic range compression and local contrast enhancement are achieved simultaneously.
Effect of the Fast Nuclear Electromagnetic Pulse on the Electric Power Grid Nationwide: A Different View

This paper primarily considers the potential effects of a single high-altitude nuclear burst on the U.S. power grid. A comparison is made between EMP and natural phenomena such as lightning. This paper concludes that EMP is no more harmful to the power grid than its counterparts in nature. An upper limit of the electric field of the very fast, high-amplitude EMP is derived from first principles. The resulting values are significantly lower than the commonly presented values. Additional calculations show that the ionization produced by a nuclear burst severely attenuates the EMP.
OS DOIS CIRCUITOS DA ECONOMIA URBANA NA CIDADE DE ILHÉUS: O CIRCUITO INFERIOR DA PESCA

O presente trabalho é resultado de pesquisa que está sendo realizada junto ao Programa de Pós-graduação em Geografia do Instituto de Geociências da Unicamp. Nossa pesquisa baseia-se no estudo dos circuitos espaciais produtivos (MORAES, 1989; SANTOS & SILVEIRA, 2001; SANTOS, 2004). Essa abordagem de método constitui um tipo de estudo imprescindível para que se entenda a dinâmica produtiva dos países periféricos num contexto de globalização. A partir da compreensão do funcionamento dos circuitos, pode-se melhor entender as crises que tanto perturbam o território hoje. Neste artigo procuramos fazer uma abordagem preliminar sobre os agentes envolvidos no circuito espacial produtivo da pesca em Ilhéus (BA), enfatizando o circuito inferior, mas procurando estabelecer as relações entretecidas entre este circuito e o circuito superior marginal da pesca, pois agentes com diferentes recursos tecnológicos e de capital imprimem lógicas distintas ao uso do território nos lugares. Consideramos a teoria dos circuitos espaciais produtivos, adequada para uma compreensão geográfica das dinâmicas socioespaciais de Ilhéus.
A surgical approach to the cavernous portion of the carotid artery. Anatomical studies and case report.

O CCASIONALLY the neurosurgeon is conf ron ted wi th a s i tua t ion in which he wishes he could safely approach and leave the cavernous por t ion of the caro t id a r te ry . Th i s paper records a case of t r a u m a t ic ca ro t id -cavernous fistula which was carried t h rough m a n y stages, inc lud ing definit ive surgery, and which i l lumina ted cer ta in re la ted a n a t o m i c a l observat ions .
Sentiment classification of online reviews: using sentence-based language model

With the development of social media, the increasing online reviews of products are greatly influencing the electronic market, making sentiment classification the topic of interest for both industry and academia. This paper develops a sentence-based language model to perform sentiment classification at a fine-grained sentence level. The proposed approach applies a machine learning method to determine the sentiment polarity of a sentence at first, then designs statistical algorithm to compute the weight of the sentence in sentiment classification of the whole document and at last aggregates the weighted sentence to predict the sentiment polarity of document. Besides, experiments are carried out on corpuses in different evaluation domains and languages, and the results demonstrate the effectiveness of the sentence-based approach in obtaining a more accurate result of sentiment classification across different reviews. Furthermore, the experimental results also indicate that the position and the sentiment of a sentence have great impact on predicting the sentiment polarity of document, and corpuses with different evaluative objects, languages and sentiments also greatly influence the performance of sentiment classification. It is believed that these conclusions will be a good inspiration for similar researches.
Identification of the promoter region for the colanic acid polysaccharide biosynthetic genes in Escherichia coli K-12

The colanic acid polysaccharide capsule biosynthetic genes (cps genes) are primarily clustered at one site located at about 45 min on the Escherichia coli chromosome. The network of proteins involved in regulating the expression of these genes includes the two positive regulators RcsA and RcsB. This work describes the site of action of these two activator proteins and the promoter of the cps genes. It is likely that the cps genes are arranged in a single long operon that is at least 13.5 kb. The promoter region was identified with fusions to lacZ that resulted in regulated expression by the Rcs network of regulatory proteins, and the start site of transcription was identified by primer extension. The operator region was cloned from Kohara phage to multicopy plasmids and identified by titrating RcsA or RcsB. Sequence analysis of the promoter and operator region revealed homology to the JUMPstart element found in the untranslated region of many exopolysaccharide biosynthetic operons. In addition, the deduced amino acid sequence of the amino terminus of the first open reading frame of the cps operon was found to be homologous to proteins encoded by the exopolysaccharide biosynthetic operons of Klebsiella pneumoniae and Erwinia amylovora.
Use of standardized SCID-hu Thy/Liv mouse model for preclinical efficacy testing of anti-human immunodeficiency virus type 1 compounds

We have developed standardized procedures and practices for infection of SCID-hu Thy/Liv mice with human immunodeficiency virus type 1 for the prophylactic administration of antiviral compounds and for evaluation of the antiviral effect in vivo. Endpoint analyses included quantitation of viral load by intracellular p24 enzyme-linked immunosorbent assay, DNA PCR for the presence of proviral genomes, flow cytometry to measure the representation of CD4+ and CD8+ cells, and cocultivation for the isolation of virus. Efficacy tests in this model are demonstrated with the nucleoside analogs zidovudine and dideoxyinosine and with the nonnucleoside reverse transcriptase inhibitor nevirapine. This small-animal model should be particularly useful in the preclinical prioritization of lead compounds within a common chemical class, in the evaluation of alternative in vivo dosing regimens, and in the determination of appropriate combination therapy in vivo.