Miracle-dz/UniFAR-FTUs huggingface dataset:
The influence of the single stereotype on moral judgments

Stereotypes can powerfully influence people’s moral judgments. For example, stereotypes of atheists lead people to report immoral behavior as more consistent for atheists than Christians (Wright & Nichols, 2014). When targets are labeled as “obese” or “hippie”, perceivers morally judge them more harshly than targets who are not assigned such labels (Masicampo, Barth, & Ambady, 2014). However, limited research has examined how stereotypes of single people can influence perceivers’ moral judgments. Because of various negative stereotypes people hold about single people (Conley & Collins, 2002; DePaulo & Morris, 2005), it was anticipated that people would morally judge a single target more harshly than a romantically attached target, especially if they were romantically attached themselves. Two hundred and twenty Turkers and 202 college students completed an online study in which they judged how honest 8 people were, based on a description of that person (which included their relationship status) and their behavior in a 2 (relationship status of target) by 2 (neutral vs. dishonest behavior) withinparticipants design. Participants indicated their own relationship status and were primed to think about that status (e.g., by describing how being in a relationship or being single felt) prior to rating the targets. Across both samples, perceivers judged targets’ dishonest behaviors more harshly than their neutral behaviors, and perceivers also judged single targets more harshly than attached targets. There were no effects for relationship status of the participants, which indicates that single perceivers judged single targets as harshly as attached perceivers. This study provides further evidence of how mixed stereotypes of certain target groups can influence people’s perceptions and judgments of those groups.
[Jealousy in close relationships: personal, relational and situational variables].

PURPOSE In this study, the effects of personal, situational, and relational variables (such as age, gender, gender role orientation, duration of relationship, relational satisfaction, and physical attractiveness of the partner) on jealousy are investigated. METHODS A sample of 454 individuals currently involved in dating or marital relationships (48 % married, 52 % unmarried) completed the Romantic Jealousy Questionnaire, Bem Sex Role Inventory, and Rosenberg Self-Esteem Scale. Stepwise regression analyses and 2 (gender) x2 (gender role orientation) x2 (relational type) ANOVA's were submitted for analyzing the data. RESULTS Analysis indicated that unmarried people reported higher levels of jealousy than married people (F1-446 = 5.029). Married women reported less jealousy than unmarried women and married women reported more jealousy than married men. Age, relational satisfaction level, expectation level about the duration of the relationship, and physical attractiveness of the partner were unique predictors of the reported level of jealousy (R2 = 0.12; adjusted R2 = 0.11; P < 0.05). Women reported that they have more physical, emotional, and cognitive responses to jealousy compared to men. Women used more constructive (F1-446 = 6.27) and less destructive strategies than men (F1-446 = 6.27). Unmarried people used more destructive strategies than married people (F1-446 = 3.84). Age, self-esteem, and the duration of the relationship were unique predictors of coping strategies. CONCLUSION The present study revealed that jealousy was a multidimensional variable. In particular, relational type, self-esteem, age, relational satisfaction, and sex are highly correlated with jealousy.
Developmentally-Oriented Safety Surveys

A series of developmentally-oriented safety surveys has been utilized in both private practice and clinic settings in an effort to systematize safety counseling in a practical and meaningful manner, and to provide data com paring the educational needs of various socioeconomic and ethnic groups. Extraordinary deficiencies were identified in parental awareness and reported practice of basic accident prevention techniques at all levels and in all social and ethnic groups.
Exploring terra incognita: wayfinding devices for games

The ludic experience of exploring wilderness in gameworlds may be compromised by either the negative affects of disorientation or the conspicuous application of architectural principles known to support wayfinding. We use a novel device, inspired by insect navigation, to examine players' situated acquisition of spatial knowledge to enable them return to the origin of their route while they explore an unfamiliar, synthetic natural world. We describe qualitative and quantitative data on player behaviour and distill themes to inform subsequent designs to assist players fulfillment when exploring settings and interpreting them spatially.
A Nodal Based Evolutionary StructuralOptimisation Algorithm

This paper proposes a simple and interesting algorithm dealing with structural shape, topology and thickness optimisation simultaneously. The proposed approach is based on an interesting idea of migrating boundary nodes in an iterative manner. An intuitive nodal-based evolutionary structural algorithm drives the optimisation process. Finite element analysis is required at each stage to reveal the relative stress distribution of the evolving structure, from which the lowly stressed edge nodes are identified as design variables and shift towards the higher stressed areas within the design domain during optimisation. Migrating the geometry boundary nodes directly changes the structural shape and thus perform shape optimisation. By introducing a fixed shape circular cavity into the evolving structure during optimisation initiates topology optimisation. Further shifting the cavity boundary nodes during optimisation gradually reveals the structural topology. In addition, nodal thickness is gradually decreased to enhance the reduction of structural weight. One feature of this nodal based approach is that by employing boundary nodal coordinates as design variables the interior finite element mesh becomes irrelevant to the shape definition of structures, thus unstructured mesh may be used. This enhances the compatibility on integrating the proposed algorithm with auto-meshing capability which is incorporated in most commercial finite element software today. A couple of benchmark problems, including the classical MBB beam, are used for illustration purposes.
Lamin A/C–mediated neuromuscular junction defects in Emery-Dreifuss muscular dystrophy

The LMNA gene encodes lamins A and C, two intermediate filament-type proteins that are important determinants of interphase nuclear architecture. Mutations in LMNA lead to a wide spectrum of human diseases including autosomal dominant Emery-Dreifuss muscular dystrophy (AD-EDMD), which affects skeletal and cardiac muscle. The cellular mechanisms by which mutations in LMNA cause disease have been elusive. Here, we demonstrate that defects in neuromuscular junctions (NMJs) are part of the disease mechanism in AD-EDMD. Two AD-EDMD mouse models show innervation defects including misexpression of electrical activity–dependent genes and altered epigenetic chromatin modifications. Synaptic nuclei are not properly recruited to the NMJ because of mislocalization of nuclear envelope components. AD-EDMD patients with LMNA mutations show the same cellular defects as the AD-EDMD mouse models. These results suggest that lamin A/C–mediated NMJ defects contribute to the AD-EDMD disease phenotype and provide insights into the cellular and molecular mechanisms for the muscle-specific phenotype of AD-EDMD.
Fouling Resistant CA/PVA/TiO2 Imprinted Membranes for Selective Recognition and Separation Salicylic Acid from Waste Water

Highly selective cellulose acetate (CA)/poly (vinyl alcohol) (PVA)/titanium dioxide (TiO2) imprinted membranes were synthesized by phase inversion and dip coating technique. The CA blend imprinted membrane was synthesized by phase inversion technique with CA as membrane matrix, polyethyleneimine (PEI) as the functional polymer, and the salicylic acid (SA) as the template molecule. The CA/PVA/TiO2 imprinted membranes were synthesized by dip coating of CA blend imprinted membrane in PVA and different concentration (0.05, 0.1, 0.2, 0.4 wt %) of TiO2 nanoparticles aqueous solution. The SEM analysis showed that the surface morphology of membrane was strongly influenced by the concentration of TiO2 nanoparticles. Compared with CA/PVA-TiO2(0.05, 0.1, 0.2%)-MIM, the CA/PVA-TiO2(0.4%)-MIM possessed higher membrane flux, kinetic equilibrium adsorption amount, binding capacity and better selectivity for SA. It was found that the pseudo-second-order kinetic model was studied to describe the kinetic of CA/PVA-TiO2(0.2%)-MIM judging by multiple regression analysis. Adsorption isotherm analysis indicated that the maximum adsorption capacity for SA were 24.43 mg g−1. Moreover, the selectivity coefficients of CA/PVA-TiO2 (0.2%)-MIM for SA relative to p-hydroxybenzoic acid (p-HB) and methyl salicylate (MS) were 3.87 and 3.55, respectively.
RBM5 Is a Male Germ Cell Splicing Factor and Is Required for Spermatid Differentiation and Male Fertility

Alternative splicing of precursor messenger RNA (pre-mRNA) is common in mammalian cells and enables the production of multiple gene products from a single gene, thus increasing transcriptome and proteome diversity. Disturbance of splicing regulation is associated with many human diseases; however, key splicing factors that control tissue-specific alternative splicing remain largely undefined. In an unbiased genetic screen for essential male fertility genes in the mouse, we identified the RNA binding protein RBM5 (RNA binding motif 5) as an essential regulator of haploid male germ cell pre-mRNA splicing and fertility. Mice carrying a missense mutation (R263P) in the second RNA recognition motif (RRM) of RBM5 exhibited spermatid differentiation arrest, germ cell sloughing and apoptosis, which ultimately led to azoospermia (no sperm in the ejaculate) and male sterility. Molecular modelling suggested that the R263P mutation resulted in compromised mRNA binding. Within the adult mouse testis, RBM5 localises to somatic and germ cells including spermatogonia, spermatocytes and round spermatids. Through the use of RNA pull down coupled with microarrays, we identified 11 round spermatid-expressed mRNAs as putative RBM5 targets. Importantly, the R263P mutation affected pre-mRNA splicing and resulted in a shift in the isoform ratios, or the production of novel spliced transcripts, of most targets. Microarray analysis of isolated round spermatids suggests that altered splicing of RBM5 target pre-mRNAs affected expression of genes in several pathways, including those implicated in germ cell adhesion, spermatid head shaping, and acrosome and tail formation. In summary, our findings reveal a critical role for RBM5 as a pre-mRNA splicing regulator in round spermatids and male fertility. Our findings also suggest that the second RRM of RBM5 is pivotal for appropriate pre-mRNA splicing.
Listening for the Norm: Adaptive Coding in Speech Categorization

Perceptual aftereffects have been referred to as “the psychologist’s microelectrode” because they can expose dimensions of representation through the residual effect of a context stimulus upon perception of a subsequent target. The present study uses such context-dependence to examine the dimensions of representation involved in a classic demonstration of “talker normalization” in speech perception. Whereas most accounts of talker normalization have emphasized talker-, speech-, or articulatory-specific dimensions’ significance, the present work tests an alternative hypothesis: that the long-term average spectrum (LTAS) of speech context is responsible for patterns of context-dependent perception considered to be evidence for talker normalization. In support of this hypothesis, listeners’ vowel categorization was equivalently influenced by speech contexts manipulated to sound as though they were spoken by different talkers and non-speech analogs matched in LTAS to the speech contexts. Since the non-speech contexts did not possess talker, speech, or articulatory information, general perceptual mechanisms are implicated. Results are described in terms of adaptive perceptual coding.
A novel feeding structure for second higher order mode excitation of microstrip leaky-wave antenna

This paper proposes a novel feeding structure for exciting the second higher order leaky mode of microstrip antenna. By properly designing the three excitation points at the input port, the second higher order leaky mode can be purely excited. The fundamental and first higher order leaky mode cannot be excited due to the unequal power amplitude and phase at different excitation points. The prototyped antenna achieves the beam scanning range 30° when the frequency is swept between 12.5 GHz and 13.7 GHz. The simulated peak gain is 13.2 dB and the gain flatness is 2.3-dB variation with the 9% return loss bandwidth. The measured 10-dB return loss is obtained over the leaky band with 13.1 dB peak gain.
A provisional regulatory gene network for specification of endomesoderm in the sea urchin embryo.

We present the current form of a provisional DNA sequence-based regulatory gene network that explains in outline how endomesodermal specification in the sea urchin embryo is controlled. The model of the network is in a continuous process of revision and growth as new genes are added and new experimental results become available; see http://www.its. caltech.edu/~mirsky/endomeso.htm (End-mes Gene Network Update) for the latest version. The network contains over 40 genes at present, many newly uncovered in the course of this work, and most encoding DNA-binding transcriptional regulatory factors. The architecture of the network was approached initially by construction of a logic model that integrated the extensive experimental evidence now available on endomesoderm specification. The internal linkages between genes in the network have been determined functionally, by measurement of the effects of regulatory perturbations on the expression of all relevant genes in the network. Five kinds of perturbation have been applied: (1) use of morpholino antisense oligonucleotides targeted to many of the key regulatory genes in the network; (2) transformation of other regulatory factors into dominant repressors by construction of Engrailed repressor domain fusions; (3) ectopic expression of given regulatory factors, from genetic expression constructs and from injected mRNAs; (4) blockade of the beta-catenin/Tcf pathway by introduction of mRNA encoding the intracellular domain of cadherin; and (5) blockade of the Notch signaling pathway by introduction of mRNA encoding the extracellular domain of the Notch receptor. The network model predicts the cis-regulatory inputs that link each gene into the network. Therefore, its architecture is testable by cis-regulatory analysis. Strongylocentrotus purpuratus and Lytechinus variegatus genomic BAC recombinants that include a large number of the genes in the network have been sequenced and annotated. Tests of the cis-regulatory predictions of the model are greatly facilitated by interspecific computational sequence comparison, which affords a rapid identification of likely cis-regulatory elements in advance of experimental analysis. The network specifies genomically encoded regulatory processes between early cleavage and gastrula stages. These control the specification of the micromere lineage and of the initial veg(2) endomesodermal domain; the blastula-stage separation of the central veg(2) mesodermal domain (i.e., the secondary mesenchyme progenitor field) from the peripheral veg(2) endodermal domain; the stabilization of specification state within these domains; and activation of some downstream differentiation genes. Each of the temporal-spatial phases of specification is represented in a subelement of the network model, that treats regulatory events within the relevant embryonic nuclei at particular stages.
Effect of body position on cranial migration of epidurally injected methylene blue in recumbent dogs.

OBJECTIVE To determine the relationship between different body positions during recumbency on the cranial migration of epidurally injected methylene blue in canine cadavers. SAMPLE POPULATION 21 fresh cadavers of clinically normal adult female mixed-breed dogs. PROCEDURE Dogs were randomly assigned to the following 3 groups: dogs remaining in right lateral recumbency (n = 7), dogs rotated from left to right lateral recumbency (7), and dogs rotated from dorsal to right lateral recumbency (7). Each dog received an epidural injection of 0.05% methylene blue (0.1 mL/kg) at the lumbosacral space. A dorsal laminectomy of the vertebral column was made, and cranial extent of methylene blue in 4 quadrants (right lateral, left lateral, ventral, and dorsal) was determined by examining dura mater staining. RESULTS No significant difference was found among groups in regard to body weight or body condition score. Epidural cranial migration of methylene blue in the right lateral quadrant was significantly greater in dogs that remained in right lateral recumbency than in dogs that were rotated from left to right lateral recumbency. No significant difference was found within groups for epidural cranial migration of methylene blue between each quadrant. No significant relationship was found between body weight or body condition score and epidural cranial migration of methylene blue. CONCLUSIONS AND CLINICAL RELEVANCE Body positioning and amount of recumbency time influence cranial migration of epidurally injected methylene blue. If greater cranial migration of an epidurally administered drug is desired, placing the patient in lateral recumbency with the surgical site on the dependent side may precede surgery.
Effect of Protein Ingestion on the Glucose and Insulin Response to a Standardized Oral Glucose Load

Type II diabetic subjects were given 50 g protein, 50 g glucose, or 50 g glucose with 50 g protein as a single meal in random sequence. The plasma glucose and insulin response was determined over the subsequent 5 h. The plasma glucose area above the baseline following a glucose meal was reduced 34% when protein was given with the glucose. When protein was given alone, the glucose concentration remained stable for 2 h and then declined. The insulin area following glucose was only modestly greater than with a protein meal (97 ± 35, 83 ± 19 µU · h/ml, respectively). When glucose was given with protein, the mean insulin area was considerably greater than when glucose or protein was given alone (247 ± 33 µU · h/ml). When various amounts of protein were given with 50 g glucose, the insulin area response was essentially first order. Subsequently, subjects were given 50 g glucose or 50 g glucose with 50 g protein as two meals 4 h apart in random sequence. The insulin areas were not significantly different for each meal but were higher when protein + glucose was given. After the second glucose meal the plasma glucose area was 33% less than after the first meal. Following the second glucose + protein meal the plasma glucose area was markedly reduced, being only 7% as large as after the first meal. These data indicate that protein given with glucose will increase insulin secretion and reduce the plasma glucose rise in at least some type II diabetic persons.
A memetic algorithm for the multi-objective flexible job shop scheduling problem

In this paper, a new memetic algorithm (MA) is proposed for the muti-objective flexible job shop scheduling problem (MO-FJSP) with the objectives to minimize the makespan, total workload and critical workload. By using well-designed chromosome encoding/decoding scheme and genetic operators, the non-dominated sorting genetic algorithm II (NSGA-II) is first adapted for the MO-FJSP. Then the MA is developed by incorporating a novel local search algorithm into the adapted NSGA-II, where several mechanisms to balance the genetic search and local search are employed. In the proposed local search, a hierarchical strategy is adopted to handle the three objectives, which mainly considers the minimization of makespan, while the concern of the other two objectives is reflected in the order of trying all the possible actions that could generate the acceptable neighbor. Experimental results on well-known benchmark instances show that the proposed MA outperforms significantly two off-the-shelf multi-objective evolutionary algorithms and four state-of-the-art algorithms specially proposed for the MO-FJSP.
The relationship between personality preferences and the emotional intelligence of postgraduate management students

Effective management is often related to emotional intelligence. The emotional intelligence of managers may relate to their personality characteristics. The objective of this study was to assess the relationship between emotional intelligence and personality preferences. A cross-sectional design was used. The study population consisted of Management students at a business school (N = 71). The Bar-On Emotional Quotient Inventory (EQ-i) and the Myers-Briggs Type Indicator (MBTI) were used as measuring instruments. The results showed that there is a significant relationship between emotional intelligence and preferences for Extraversion, Intuition, Feeling and Perception.
Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit

The target of rapamycin (TOR) protein kinase forms multi-subunit TOR complex 1 (TORC1) and TOR complex 2 (TORC2), which exhibit distinct substrate specificities. Sin1 is one of the TORC2-specific subunit essential for phosphorylation and activation of certain AGC-family kinases. Here, we show that Sin1 is dispensable for the catalytic activity of TORC2, but its conserved region in the middle (Sin1CRIM) forms a discrete domain that specifically binds the TORC2 substrate kinases. Sin1CRIM fused to a different TORC2 subunit can recruit the TORC2 substrate Gad8 for phosphorylation even in the sin1 null mutant of fission yeast. The solution structure of Sin1CRIM shows a ubiquitin-like fold with a characteristic acidic loop, which is essential for interaction with the TORC2 substrates. The specific substrate-recognition function is conserved in human Sin1CRIM, which may represent a potential target for novel anticancer drugs that prevent activation of the mTORC2 substrates such as AKT. DOI: http://dx.doi. org/10.7554/eLife.19594. 001
Error-tolerant interactive image segmentation using dynamic and iterated graph-cuts

Efficient and accurate interactive image segmentation have significant importance in many multimedia applications. For mobile touchscreen-based applications, efficiency is more crucial. Moreover, due to small screens of the mobile devices, error tolerance is also a crucial factor. In this paper, a method for interactive image segmentation, tailored for mobile touch screen devices, is proposed. As an interaction methodology, coloring is presented. An automatic stroke-error correction methodology to correct the inaccurate user interaction is also proposed. For the efficient computation of the solution, a novel dynamic and iterative graph-cut solution is formulated. Efficiency and error tolerance of the proposed method are tested by using various sample images. Subjective evaluation of the interactive segmentation algorithms for mobile-touch screen is also performed. Indeed, for the challenging examples, the superior performance of the proposed method is obtained by the experiments.