Miracle-dz/UniFAR-FTUs huggingface dataset:
Research on Learning to Read and Spell: A Personal-Historical Perspective

Ehri delivered this presidential address at the annual meeting of the Society for the Scientific Study of Reading, March 1997, Chicago. Ehri provides a glimpse of her experiences conducting research on word-reading processes in beginning readers for more than 20 years. At the outset, she proposed a theory that the spellings of individual words become bonded to their pronunciations in memory, and she conducted studies to obtain evidence for this theory. This led her into various controversies with other researchers over issues such as whether phonemic awareness is a cause or consequence of learning to read and to what extent beginning readers use visual cues or alphabetic cues to read their first words. The disagreements proving most fruitful were those that spawned additional research. Disputes considered unproductive and even harmful were those involving dogmatic views not open to empirical evidence and maligning appelations intended to implant prejudice. This recounting of her career underscores the val.
ON THE AMBARTSUMIAN FUNCTIONAL EQUATION

In this work, we define the pantograph functional equation with parameter and study the existence of solutions in two classes x ∈ C [0 ,T ] and x ∈ L 1 [0 ,T ], we use the technique of the Banach fixed point theorem and Schauder fixed point Theorem. In both cases we study the continuous dependence of the unique solution on the pantograph functional equation. The Hyers–Ulam stability will be studied. Additionally, we give an example to illustrate our outcomes.
Social, Cultural, and Political Influences on the Development of an Educational Partnership

This case study focused on the development of an educational partnership between State U. and 2 underperforming high schools in southern California. The partnership was a collaborative effort between State U. and the schools to improve Latino student eligibility for college. Institutional theory was used to conceptualize how the interaction of culture and organizational features shaped decisions and actions made by individuals involved in the partnership formation. Our findings suggest that partnership formation depends on development of mutual respect and for administrators to monitor and address issues as they arise. Future analysis of school-university partnership should involve examining individuals' actions and decisions in the process of partnership development.
Domain Inference in Incremental Interpretation

Speakers in dialogue describe domain-specific actions, goals, conditions and plans using the general resources of their linguistic knowledge. Interlocutors must recognize these descriptive connections through inference—and they must do so incrementally, since they need interpretations of partial utterances to inform their on-line participation in conversational interaction. This paper explores techniques that dialogue systems can use to achieve incremental interpretation, even when domain reasoning is modular, genuinely nonlinguistic and potentially expensive. We base our discussion on an implemented prototype natural language interface, figlet, that combines plan-recognition with real and discrete constraint-satisfaction to interpret English instructions in a drawing domain. figlet provides a proof-of-concept of the feasibility of such incremental interpretation, a testbed for the quantitative evaluation of the tradeoffs involved, and a case study in the methodological challenges that remain for future work.
Factors affecting organisational creativity and innovativeness in Egyptian business organisations: an empirical investigation

Purpose – The overall purpose of this research is to further our understanding of how managers in Egypt perceive creativity and innovativeness. The paper also examines the construct validity of two measures of creativity and creativity barriers in order to gain further insights into the factors stimulating or hindering creativity in Egypt.Design/methodology/approach – A sample of 170 managers was used to achieve the research purpose. Based on the upper‐echelon perspective, the sample slightly favours high‐level managers. Respondents completed a 77‐item instrument designed to assess stimulants‐to‐creativity in the organisational workplace. A 17‐item barriers‐to‐creativity instrument was also used to assess barriers to creativity in Egypt's organisations.Findings – The study detected a statistically significant difference in attitudes towards organisational creativity based on the managers’ functional areas in the organisation. The study also shows that the greater the education of the manager, the more he .
Carcass traits, fatty acid composition, gene expression, oxidative stability and quality attributes of different muscles in Dorper lambs fed Nigella sativa seeds, Rosmarinus officinalis leaves and their combination

Objective This study examined the influence of dietary supplementation of Nigella sativa seeds, Rosmarinus officinalis leaves and their combination on carcass attributes, fatty acid (FA) composition, gene expression, lipid oxidation and physicochemical properties of longissimus dorsi (LD), semitendinosus (ST), and supraspinatus (SS) muscles in Dorper lambs. Methods Twenty-four Dorper lambs (18.68±0.6 kg, 4 to 5 months old) were randomly assigned to a concentrate mixture containing either, no supplement (control, T1), 1% Rosmarinus officinalis leaves (T2), 1% Nigella sativa seeds (T3), or 1% Rosmarinus officinalis leaves+1% Nigella sativa seeds (T4) on a dry matter basis. The lambs were fed the treatments with urea-treated rice straw for 90 days, slaughtered and the muscles were subjected to a 7 d postmortem chill storage. Results The T2 lambs had greater (p<0.05) slaughter and cold carcass weights than the control lambs. Dietary supplements did not affect (p>0.05) chill loss, dressing percentage, carcass composition, intramuscular fat and muscle pH in Dorper lambs. Meat from supplemented lambs had lower (p<0.05) cooking and drip losses, shear force, lightness, and lipid oxidation and greater (p<0.05) redness compared with the control meat. The impact of dietary supplements on muscle FA varied with muscle type. Diet had no effect (p>0.05) on the expression of stearoyl-CoA desaturase and lipoprotein lipase genes in LD and ST muscles in Dorper lambs. The T2 and T3 diets up regulated the expression of AMP-activated protein kinase alpha 2 gene in LD and ST muscles and up regulated the expression of sterol regulatory element-binding protein 1 in ST muscle in Dorper lambs. Conclusion Dietary supplementation of Nigella sativa seeds and Rosmarinus officinalis leaves had beneficial effects on meat quality in Dorper lambs.
Dietary red chilli (Capsicum frutescens L.) is insulinotropic rather than hypoglycemic in type 2 diabetes model of rats

The present study was conducted to clarify whether a low or a high, but tolerable, dietary dose of red chilli (RC) can ameliorate the diabetes related complications in a high‐fat (HF) diet‐fed streptozotocin (STZ)‐induced type 2 diabetes model of rats. Five‐week‐old male Sprague Dawley rats were fed a HF diet for 2 weeks then randomly divided into four groups namely: normal control (NC), diabetic control (DBC), red chilli low (RCL, 0.5%) and red chilli high (RCH, 2.0%) groups. Diabetes was induced by an intraperitoneal (i.p.) injection of STZ (40 mg/kg BW) in all groups except the NC group. After 4 weeks feeding of experimental diets, the fasting blood glucose concentrations in both RC fed groups were not significantly different. The serum insulin concentration was significantly (p < 0.05) increased in the RCH group compared with the DBC and RCL groups. Blood HbA1c, liver weight, liver glycogen and serum lipids were not influenced by the feeding of RC‐containing diets. The data of this study suggest that 2% dietary RC is insulinotropic rather than hypoglycemic at least in this experimental condition. Copyright © 2008 John Wiley & Sons, Ltd.
Structural SVMs for Defining Payment Rules in Combinatorial Auctions

A major challenge in combinatorial auctions is to construct payment rules to make a winner-determination algorithm maximally incentive compatible. A general purpose solution is available only when winner case for reasons of computational complexity or other economic considerations. We propose to use structural SVMs for this pricing problem. The decision boundaries for each target class (with a class corresponding to the allocation of a bundle to an agent) combine to define a payment rule. An exact classifier produces a payment rule that makes the auction incentive compatible. Minimizing regularized empirical risk in solving the structural SVM training problem minimizes a regularized upper bound on empirical regret.
Forensically Important Blow Flies Chrysomya pinguis, C. villeneuvi, and Lucilia porphyrina (Diptera: Calliphoridae) in a Case of Human Remains in Thailand

This is the first study to report Chrysomya pinguis (Walker) and Lucilia porphyrina (Walker) (Diptera: Calliphoridae) as forensically important blow fly species from human cadavers in Thailand, in addition to Chrysomya villeneuvi (Patton) already known in Thailand. In 2016, a fully decomposed body of an unknown adult male was discovered in a high mountainous forest during winter in Chiang Mai province. The remains were infested heavily with thousands of blow fly larvae feeding simultaneously on them. Morphological identification of adults reared from the larvae, and molecular analysis based on sequencing of 1,247 bp partial mitochondrial cytochrome c oxidase subunit 1 gene (CO1) of the larvae and puparia, confirmed the above mentioned 3 species. The approving forensic fly evidence by molecular approach was described for the first time in Thailand. Moreover, neighbor-joining phylogenetic analysis of the CO1 was performed to compare the relatedness of the species, thereby affirming the accuracy of identification. As species of entomofauna varies among cases in different geographic and climatic circumstances, C. pinguis and L. porphyrina were added to the list of Thai forensic entomology caseworks, including colonizers of human remains in open, high mountainous areas during winter. Further research should focus on these 3 species, for which no developmental data are currently available.
Compact FPGA implementation of PRESENT with Boolean S-Box

Ever since the conception of the ideology known as the Internet of Things (IoT), our world is slowly approaching the brink of mankind's next technological revolution. The realization of IoT requires an enormous amount of sensor nodes to acquire inputs from the connected objects. Due to the lightweight nature of these sensors, constraints emerge in the form of limited power supply and area for the implementation of information security mechanism. To ensure security in the data transmitted by these sensors, lightweight cryptographic solutions are required. In this work, our goal is to implement a compact PRESENT cipher onto a Field Programmable Gate Array (FPGA) platform. Our proposed design uses an 8-bit datapath to reduce hardware size. Instead of a traditional look-up table (LUT) based S-Box, we have implemented a Boolean S-Box through Karnaugh mapping. Further factorization is also done to reduce the size of the Boolean S-Box. As a result, we have achieved the smallest FPGA implementation of the PRESENT cipher to date, requiring only 62 slices on the Virtex-5 XC5VLX50 platform. Our design also features a respectable throughput of 51.32 Mbps at the maximum frequency of 236.574 MHz.
The role of aspirin in the prevention of thrombotic complications of thalidomide and anthracycline-based chemotherapy for multiple myeloma.

OBJECTIVE To study the efficacy of daily low-dose aspirin (81 mg orally) in decreasing the incidence of venous thromboembolic events (VTEs) in patients with multiple myeloma receiving pegylated doxorubicin, vincristine, and decreased-frequency dexamethasone, plus thalidomide (DVd-T). PATIENTS AND METHODS In this phase 2 clinical trial of DVd-T, conducted by the Cleveland Clinic Foundation from August 2001 to October 2003, 105 patients were enrolled. The first 35 patients experienced increased numbers of VTEs. von Willebrand levels and platelet aggregation to ristocetin before and after treatment with DVd-T increased significantly, suggesting a pathophysiology involving platelet-endothelial interaction. Aspirin was added to the regimen, thus generating 3 patient groups: group 1 received aspirin from the start of DVd-T treatment before the study began (58 patients), group 2 received aspirin after the start of DVd-T treatment and after the study began (26 patients), and group 3 did not receive daily low-dose aspirin during the study (19 patients). Two patients being treated with warfarin for other indications were excluded from the study. The primary end point for this study was the incidence of VTE in the form of either deep venous thrombosis or pulmonary embolism. Secondary end points were the time to the first VTE, time to the composite end point of death or first VTE, and incidence of bleeding complications. RESULTS After a median follow-up of 24 months, on an intent-to-treat basis, 26 posttreatment VTEs occurred after a median of 90 days, with 19% occurring in group 1, 15% in group 2, and 58% in group 3. Following multivariate time-to-event analysis, aspirin use continued to be associated with lower relative risk of VTE (hazard ratio, 0.22; confidence interval, 0.10-0.47; P<.001) and of the composite end point (hazard ratio, 0.28; confidence interval, 0.15-0.51; P<.001). CONCLUSION Daily low-dose aspirin (81 mg orally) given to patients with newly diagnosed and relapsed/refractory multiple myeloma who were receiving DVd-T reduced the incidence of VTEs without an increase in bleeding complications.
Unsupervised Stemmer for Arabic Tweets

Stemming is an essential processing step in a wide range of high level text processing applications such as information extraction, machine translation and sentiment analysis. It is used to reduce words to their stems. Many stemming algorithms have been developed for Modern Standard Arabic (MSA). Although Arabic tweets and MSA are closely related and share many characteristics, there are substantial differences between them in lexicon and syntax. In this paper, we introduce a light Arabic stemmer for Arabic tweets. Our results show improvements over the performance of a number of well-known stemmers for Arabic.
Impairing the production of ribosomal RNA activates mammalian target of rapamycin complex 1 signalling and downstream translation factors

Ribosome biogenesis is a key process for maintaining protein synthetic capacity in dividing or growing cells, and requires coordinated production of ribosomal proteins and ribosomal RNA (rRNA), including the processing of the latter. Signalling through mammalian target of rapamycin complex 1 (mTORC1) activates all these processes. Here, we show that, in human cells, impaired rRNA processing, caused by expressing an interfering mutant of BOP1 or by knocking down components of the PeBoW complex elicits activation of mTORC1 signalling. This leads to enhanced phosphorylation of its substrates S6K1 and 4E-BP1, and stimulation of proteins involved in translation initiation and elongation. In particular, we observe both inactivation and downregulation of the eukaryotic elongation factor 2 kinase, which normally inhibits translation elongation. The latter effect involves decreased expression of the eEF2K mRNA. The mRNAs for ribosomal proteins, whose translation is positively regulated by mTORC1 signalling, also remain associated with ribosomes. Therefore, our data demonstrate that disrupting rRNA production activates mTORC1 signalling to enhance the efficiency of the translational machinery, likely to help compensate for impaired ribosome production.
Different Isolation Methods Alter the Gene Expression Profiling of Adipose Derived Stem Cells

Human adipose stem cells (ASCs) has been in the limelight since its discovery as a suitable source of mesenchymal stem cells (MSCs) in regenerative medicine. Currently, two major techniques are used to isolate ASCs, namely liposuction and tissue biopsy. These two methods are relatively risk-free but the question as to which method could give a more efficient output remains unclear. Thus, this study was carried out to compare and contrast the output generated in regards to growth kinetics, differentiation capabilities in vitro, and gene expression profiling. It was found that ASCs from both isolation methods were comparable in terms of growth kinetics and tri-lineage differentiation. Furthermore, ASCs from both populations were reported as CD44+, CD73+, CD90+, CD166+, CD34-, CD45- and HLA-DR-. However, in regards to gene expression, a group of overlapping genes as well as distinct genes were observed. Distinct gene expressions indicated that ASCs (liposuction) has endoderm lineage propensity whereas ASCs (biopsy) has a tendency towards mesoderm/ectoderm lineage. This information suggests involvement in different functional activity in accordance to isolation method. In conclusion, future studies to better understand these gene functions should be carried out in order to contribute in the applicability of each respective cells in regenerative therapy.
Approaching Single-Hop Performance in Multihop Networks: End-to-End Known-Interference Cancelation (E2E-KIC)

To improve the efficiency of wireless data communications, new physical-layer transmission methods based on known-interference cancelation (KIC) have been developed. These methods share the common idea that interference can be canceled when its content is known. Existing work on KIC mainly focuses on single-hop or two-hop networks, with physical-layer network coding and full-duplex communications as typical examples. This paper extends the idea of KIC to general multihop networks and proposes an end-to-end KIC (E2E-KIC) transmission method, together with its medium access control (MAC) design. With E2E-KIC, multiple nodes in a flow passing through a few nodes in an arbitrary topology can simultaneously transmit and receive on the same channel. We first present a theoretical analysis on the effectiveness of E2E-KIC in an idealized case. Then, to support E2E-KIC in multihop networks with an arbitrary topology, we propose an E2E-KIC-supported MAC protocol (E2E-KIC MAC), which is based on an extension of the Request-to-Send/Clear-to-Send mechanism in the IEEE 802.11 MAC. We also analytically analyze the performance of the proposed E2E-KIC MAC in the presence of hidden terminals. Simulation results illustrate that the proposed E2E-KIC MAC can improve network throughput and reduce end-to-end delay.
Language development in a bimodal bilingual child with cochlear implant: A longitudinal study*

To address the negative effects of deafness on spoken language acquisition, many clinicians suggest using cochlear implant (CI) and oral education and advise against sign language, even when combined with spoken language (i.e., bilingualism), believing that it may slow down spoken language development. In a deaf child with CI who was exposed at an early age to Italian Sign Language and spoken Italian, we evaluated language development and the relationship between the two languages. The number of words/signs produced by the child consistently increased with age, and the vocabulary growth rate in spoken Italian was equivalent to that of hearing peers. Before CI, the child relied almost exclusively on sign language; after CI, he gradually shifted to spoken Italian yet still used sign language when unable to retrieve words in spoken Italian. We conclude that bimodal bilingualism may scaffold the development of spoken language also in deaf children with CI.
Junctophilin-2 is necessary for T-tubule maturation during mouse heart development.

AIMS Transverse tubules (TTs) provide the basic subcellular structures that facilitate excitation-contraction (EC) coupling, the essential process that underlies normal cardiac contractility. Previous studies have shown that TTs develop within the first few weeks of life in mammals but the molecular determinants of this development have remained elusive. This study aims to elucidate the role of junctophilin-2 (JPH2), a junctional membrane complex protein, in the maturation of TTs in cardiomyocytes. METHODS AND RESULTS Using a novel cardiac-specific short-hairpin-RNA-mediated JPH2 knockdown mouse model (Mus musculus; αMHC-shJPH2), we assessed the effects of the loss of JPH2 on the maturation of the ventricular TT structure. Between embryonic day (E) 10.5 and postnatal day (P) 10, JPH2 mRNA and protein levels were reduced by >70% in αMHC-shJPH2 mice. At P8 and P10, knockdown of JPH2 significantly inhibited the maturation of TTs, while expression levels of other genes implicated in TT development remained mostly unchanged. At the same time, intracellular Ca(2+) handling was disrupted in ventricular myocytes from αMHC- shJPH2 mice, which developed heart failure by P10 marked by reduced ejection fraction, ventricular dilation, and premature death. In contrast, JPH2 transgenic mice exhibited accelerated TT maturation by P8. CONCLUSION Our findings suggest that JPH2 is necessary for TT maturation during postnatal cardiac development in mice. In particular, JPH2 may be critical in anchoring the invaginating sarcolemma to the sarcoplasmic reticulum, thereby enabling the maturation of the TT network.
45% Power Saving in a 0.25μm BiCMOS 10Gb/s 50Ω-Terminated Packaged Active-Load Laser Driver

A 0.25mum BiCMOS laser driver based on active loads allows operation at 10Gb/s while drawing 5mA from a 1.8V supply. The design guarantees the correct matching of the driver outputs without the use of physical 50Omega load resistors. This enables a theoretical current consumption reduction of 50% (45% in the actual prototype) compared to the traditional laser-driver design.
Condensation of the forespore nucleoid early in sporulation of Bacillus species

Fluorescence microscopic examination coupled with digital videoimage analysis of 4',6-diamidino-2-phenylindole-stained sporulating cells of Bacillus megaterium or Bacillus subtilis revealed a striking condensation of the forespore nucleoid. While both mother cell and forespore compartments had equal amounts of DNA, the forespore nucleoid became greater than 2-fold more condensed than the mother cell nucleoid. The condensation of the forespore nucleoid began after only the first hour of sporulation, 2 to 3 h before expression of most forespore-specific genes including those for small, acid-soluble spore proteins, and was abolished in spo0 mutants but not in spoII or spoIII mutants. It is possible that this striking condensation of forespore DNA plays some role in modulating gene expression during sporulation.