Miracle-dz/UniFAR-FTUs huggingface dataset:
TRENDS IN PHOTOPHYSIOLOGIC CONCEPTS

The court-bookqeller of Osnabriick (a small residence town in northwestern Germany) published a book in 1799 entitled Essay of Q History of the Light Concerned with its Influence on the Whole Nature andWithout the Sense of Sight Especially on the Human Body by Johann Christof Ebermaier.l In this book our attention is called to (1) reports about knowledge and concepts of action of light in healthy and sick persons in medical science since Hippocratkv, the ancient Arabian physicians up to the contemporaries of the author; (2) references of knowledge of circadian and seasonal rhythms in living nature, especially in the normal and sick human being who seems to be dependent on daily change of light and darkness; (3) a thorough overview of photophysiologic concepts of the author and his contemporaries. In the climatic conditions of the Mediterranean region the ancient Arabian physicians seemed to have discovered very early the importance of the circadian chaltge in light and darkness and of its seasonal variation. They were not yet able to divide totally or in part between the action of light or of temperature. The action of light was thought to be transmitted not by the eyes but communicated by the whole body surface. The author a t the end of the eighteenth century came to the same conclusion: Impressed by the activity of plant metabolism just discovered in which oxygen was released (known to be vital for any type of animal life) and the expired carbon dioxide was absorbed, action of light was explained by communication of the whole organism with a “vital atmosphere,” which was thought to result from a chemical Kinding between oxygen and a gaslike, light material. Because in blind people, activity and sleeping periods were the same in regard to normal people, this experience should be evidence for the efficiency of this light-dependent “vital atmosphere,” mostly active by inspiration. Ebermaier mentioned the opinion of Fontana, first published in Berlin in 1787, who stated that light would act only on the retina, but rejected this idea. His observation of the persistence of leaf motion activity in plants under constant temperature conditions and permanent darkness was correct, and his question if there are similar correlations with the periodic activity in animals was remarkable. He gave correct descriptions of circadian rhythms in birth and death, of body temperature in healthy and sick men, of the crisis in numerous diseases in the evening, which is caused by change in
Learning Effective Representations from Clinical Notes

Clinical notes are a rich source of information about patient state. However, using them effectively presents many challenges. In this work we present two methods for summarizing clinical notes into patient-level representations. The resulting representations are evaluated on a range of prediction tasks and cohort sizes. The new representations offer significant predictive performance gains over the common baselines of Bag of Words and topic model representations across all tested tasks and cohort sizes.
A Secure DHCP Protocol to Mitigate LAN Attacks

Network security has become more of a concern with the rapid growth and expansion of the Internet. While there are several ways to provide security in the application, transport, or network layers of a network, the data link layer (Layer 2) security has not yet been adequately addressed. Data link layer protocols used in local area networks (LANs) are not designed with security features. Dynamic host configuration protocol (DHCP) is one of the most used network protocols for host configuration that works in data link layer. DHCP is vulnerable to a number of attacks, such as the DHCP rouge server attack, DHCP starvation attack, and malicious DHCP client attack. This work introduces a new scheme called Secure DHCP (S-DHCP) to secure DHCP protocol. The proposed solution consists of two techniques. The first is the authentication and key management technique that is used for entities authentication and management of security key. It is based on using Diffie-Hellman key exchange algorithm supported by the difficulty of Elliptic Curve Discrete Logarithm Problem (ECDLP) and a strong cryptographic one-way hash function. The second technique is the message authentication technique, which uses the digital signature to authenticate the DHCP messages exchanged between the clients and server.
Effects of platelet-derived growth factor and interleukin-10 on Fas/Fas-ligand and Bcl-2/Bax mRNA expression in rat hepatic stellate cells in vitro.

AIM To investigate the effects of platelet-derived growth factor(PDGF) and interleukin-10 (IL-10) on Fas/Fas-ligand and Bcl-2/Bax mRNA expressions in rat hepatic stellate cells. METHODS Rat hepatic stellate cells (HSCs) were isolated and purified from rat liver by in situ digestion of collagenase and pronase and single-step density Nycodenz gradient. After activated by culture in vitro, HSCs were divided into 4 groups and treated with nothing (group N), PDGF (group P), IL-10 (group I) and PDGF in combination with IL-10 (group C), respectively. Semi-quantitative reverse-transcriptase polymerase chain reaction (RT-PCR) analysis was employed to compare the mRNA expression levels of Fas/FasL and Bcl-2/Bax in HSCs of each group. RESULTS The expression levels of Fas between the 4 groups had no significant differences (P>0.05). FasL mRNA level in normal culture-activated HSCs (group N) was very low. It increased obviously after HSCs were treated with IL-10 (group I) (0.091+/-0.007 vs 0.385+/-0.051, P<0.01), but remained the low level after treated with PDGF alone (group P) or PDGF in combination with IL-10 (group C). Contrast to the control group, after treated with PDGF and IL-10, either alone or in combination, Bcl-2 mRNA expression was down-regulated and Bax mRNA expression was up-regulated, both following the turn from group P, group I to group C. Expression of Bcl-2 mRNA in group C was significantly lower than that in group P (0.126+/-0.008 vs 0.210+/-0.024, P<0.01). But no significant difference was found between group C and group I, as well as between group I and group P (P>0.05). Similarly, the expression of Bax in group C was higher than that in group P (0.513+/-0.016 vs 0.400+/-0.022, P<0.01). No significant difference was found between group I and group P (P>0.05). But compared with group C, Bax expressions in group I tended to decrease (0.449+/-0.028 vs 0.513+/-0.016, P<0.05). CONCLUSION PDGF may promote proliferation of HSCs but is neutral with respect to HSC apoptosis. IL-10 may promote the apoptosis of HSCs by up-regulating the expressions of FasL and Bax and down-regulating the expression of Bcl-2, which may be involved in its antifibrosis mechanism.
Multisensor integration and adaptive filtering in linear stochastic differential systems

We have derived the GMF, which represents the optimal linear combination of arbitrary number correlated estimates. Each estimate is fused by the minimum mean square error criterion. Using this formula we have derived the new suboptimal filtering algorithm. The proposed suboptimal filter can be widely used in the different areas of applications: industrial, military, space, communication, target tracking, inertial navigation and others.
Death of a Jewish Science: Psychoanalysis in the Third Reich

The best ebooks about Death Of A Jewish Science Psychoanalysis In The Third Reich that you can get for free here by download this Death Of A Jewish Science Psychoanalysis In The Third Reich and save to your desktop. This ebooks is under topic such as death of a jewish science psychoanalysis in the third reich death of a jewish science psychoanalysis in the third reich death of a jewish science psychoanalysis in the third reich death of a Ã¢Â€Â ̃jewish scienceÃ¢Â€ÂTM? psychoanalysis in nazi germany death of a jewish science psychoanalysis in the third reich death of a jewish science psychoanalysis in the third reich death of a jewish science psychoanalysis in the third reich death of a jewish american princess cagavs cagiva river 60
Context-Based Search in Software Development

Software developers usually spend a large amount of time navigating their own source code or searching for a specific source code artifact they need to work with. We propose a context-based search approach that focuses in the source code artifacts that exist in the workspace of the developer. These artifacts are stored in a knowledge base and represented using ontologies. The contextual information of the developer is used to rank the search results according to their relevance for the developer. The results of an experiment performed with two groups of developers show that our approach has a positive impact in retrieving relevant artifacts for the developer, helping them find what they need more quickly and easily.
Natural Disaster Tourism as a Type of Dark Tourism

This theoretical paper combines the academic discourse regarding a specific part of dark tourism. Based on the literature analysis, distinction of natural disasters in thanatourism was investigated, which is connected with dynamic geographical conditions. Natural disasters used to play an important role in social life by their appearance in myths and religions. Nowadays, tourists pursuing natural hazards can be divided into three groups: Those interested in natural hazards themselves; those interested in landscape deformation and experiencing emotions shortly after extreme events natural disasters occur; and finally those interested in historic places log after an extreme event takes place. An important element of the natural disaster tourism is quick access to information on the location of a disaster and the destination of a potential excursion. Natural disaster tourism suits alternative tourism, yet it is opposed culture tourism, and sustainable tourism. The paper compares types and groups of tourists. It also considers the contradictions that describe dualism, which exists in dark tourism. Keywords—Dark tourism, dualism, natural disasters, natural hazards, thanatoursim.
Efficient parallel algorithms for chordal graphs

The author gives efficient parallel algorithms for recognizing chordal graphs, finding a maximum clique and a maximum independent set in a chordal graph, finding an optimal coloring of a chordal graph, finding a breadth-first search tree and a depth-first search tree of a chordal graph, recognizing interval graphs, and testing interval graphs for isomorphism. The key to the results is an efficient parallel algorithm for finding a perfect elimination ordering. <<ETX>>
Absolute Copy Number and Relative Change in Determinations of Human Immunodeficiency Virus Type 1 RNA in Plasma: Effect of an External Standard on Kit Comparisons

ABSTRACT Use of a common set of human immunodeficiency virus type 1 (HIV-1) RNA standards eliminated differences among absolute HIV-1 RNA copy number estimates made with three commercially available assays. The relative changes in the viral RNA levels determined by the commercial assays were similar and were unaffected by the use of a common set of standards.
Altered Patterns of Heartbeat-Evoked Potentials in Depersonalization/Derealization Disorder: Neurophysiological Evidence for Impaired Cortical Representation of Bodily Signals

Objective Core features of depersonalization/derealization disorder (DPD) are emotional numbing and feelings of disembodiment. Although there are several neurophysiological findings supporting subjective emotional numbing, the psychobiology of disembodiment remains unclear. Methods Heartbeat-evoked potentials (HEPs), which are considered psychophysiological indicators for the cortical representation of afferent signals originating from the cardiovascular system, were assessed in 23 patients with DPD and 24 healthy control individuals during rest and while performing a heartbeat perception task. Results Absolute HEP amplitudes did not differ between groups. Nevertheless, healthy individuals showed higher HEPs during the heartbeat perception task than during rest, whereas no such effect was found in patients with DPD (p = .031). Patients with DPD had higher total levels of salivary &agr;-amylase than did healthy individuals (9626.6 [8200.0] versus 5344.3 [3745.8] kU min/l; p = .029), but there were no group differences in cardiovascular measures (heart rate = 76.2 [10.1] versus 74.3 [7.5] beats/min, p = .60; normalized low-frequency heart rate variability = 0.63 [0.15] versus 0.56 [0.15] normalized units, p = .099; low frequency/high frequency ratio = 249.3 [242.7] versus 164.8 [108.8], p = .10), salivary cortisol (57.5 [46.7] versus 55.1 [43.6] nmol min/l, p = .86), or cortisone levels (593.2 [260.3] versus 543.8 [257.1] nmol min/l, p = .52). Conclusions These results suggest altered cortical representation of afferent signals originating from the cardiovascular system in patients with DPD, which may be associated with higher sympathetic tone. These findings may reflect difficulties of patients with DPD to attend to their actual bodily experiences.
Ultra-Wideband Scanning Antenna Array With Rotman Lens

An ultra-wideband (6–18 GHz) phased-array antenna with a beam scanning angle of ±28° is proposed. A step-by-step design procedure consisting of beamforming network (BFN), end-launcher feed adapter, and the radiating element is presented. Microstrip Rotman lens has been designed to act as the BFN, and optimized to achieve minimum phase-error over the whole frequency range. In order to satisfy the condition needed for avoiding grating lobes, as well as achieving a wide radiation bandwidth and a high power handling capability, an $E$ -plane double-ridged horn antenna is used as the radiating element. A novel wideband end-launcher coaxial to double-ridged waveguide transition has also been developed for connecting the BFN to the antenna array. Extensive optimization procedures have been applied to the end-launched adapter together with the antenna to achieve the best return loss over the frequency band of operation. The whole system has been simulated using CST full-wave simulator. An excellent agreement between the measurements of the fabricated system and the simulated results is observed.
Golgi membrane‐associated degradation pathway in yeast and mammals

Autophagy is a cellular process that degrades subcellular constituents, and is conserved from yeast to mammals. Although autophagy is believed to be essential for living cells, cells lacking Atg5 or Atg7 are healthy, suggesting that a non‐canonical degradation pathway exists to compensate for the lack of autophagy. In this study, we show that the budding yeast Saccharomyces cerevisiae, which lacks Atg5, undergoes bulk protein degradation using Golgi‐mediated structures to compensate for autophagy when treated with amphotericin B1, a polyene antifungal drug. We named this mechanism Golgi membrane‐associated degradation (GOMED) pathway. This process is driven by the disruption of PI(4)P‐dependent anterograde trafficking from the Golgi, and it also exists in Atg5‐deficient mammalian cells. Biologically, when an Atg5‐deficient β‐cell line and Atg7‐deficient β‐cells were cultured in glucose‐deprived medium, a disruption in the secretion of insulin granules from the Golgi occurred, and GOMED was induced to digest these (pro)insulin granules. In conclusion, GOMED is activated by the disruption of PI(4)P‐dependent anterograde trafficking in autophagy‐deficient yeast and mammalian cells.
Novel approach to combined defaecation and micturition disorders with rectovaginovesicopexy

This study was conducted to investigate the results of rectovaginovesicopexy (RVVP) in patients with combined defaecation and micturition disorders. RVVP was developed from a standard procedure for different forms of defaecation disorders (the rectovaginopexy (RVP)). It is only a limited extension to the RVP and results in elevation of all three pelvic compartments.
The perception of social situations by children with autism spectrum disorders

This study investigated how children with autism spectrum disorders (ASD) make social judgments of social situations and provide justifications for their responses. Fifteen children with ASD and 15 typically developing children (ages from 9 to 13 years old) were presented with eight vignettes, based on the Dewey Story Test (Dewey, 1991) and developed for the purposes of this study. The participants rated the appropriateness (on a 4-point Likert scale) of the socially inappropriate event (test item) and non-social appropriate event (control item) in each vignette. Justifications for each rating were also elicited at the end of each vignette. The children with ASD rated socially inappropriate behaviors in vignettes no differently from their typically developing peers but rated control items as stranger. They also had a higher tendency to provide inappropriate/bizarre and don’t know/no response justifications instead of appropriate/social justifications (that reflect social awareness). The impact of the method of eliciting social judgments of social situations and its impact on findings are discussed.
Changes in Sex Hormone-Binding Globulin, Insulin, andSerum Lipids in Postmenopausal Women on aLow-Fat, High-Fiber Diet Combined With Exercise

Dietary factors including fat and fiber have been reported to play a role in the development of breast cancer, possibly mediated by changes in estradiol. Diet and exercise have been shown to affect levels of sex hormone-binding globulin (SHBG), which in turn regulate the bioavailability of estradiol. Diet and exercise also affect insulin levels, which play a role in the synthesis of SHBG, and the hormone itself is a potent mitogen for many cancer cell lines. This study was designed to measure the effects of a low-fat, high-fiber diet, combined with regular aerobic exercise, on the levels of SHBG, insulin, and serum lipids in postmenopausal women with or without hormone replacement therapy (HRT). Two groups of postmenopausal women, 11 on HRT and 11 not on HRT, underwent a low-fat (10% fat calories), high-fiber (65-70 g/day) diet-and-exercise intervention for three weeks. Serum SHBG, insulin, and lipids were measured before and after the regimen. After the intervention, SHBG levels were significantly increased for the women on HRT (44.5 ± 3.4 vs. 62 ± 6.4 nmol/l) and the women not on HRT (32.1 ± 4.6 vs. 45.5 ± 6.1 nmol/l, both changes p < 0.01). Also after the intervention, insulin levels were significantly reduced for the women on HRT (196 ± 44.4 vs. 119.8 ± 28.7 pmol/l) and the women not on HRT (144.2 ± 17.9 vs. 115.5 ± 20.8 pmol/l, both changes p < 0.01). Body mass index and total cholesterol were significantly reduced for both groups of women (all changes p < 0.01). Although the exact mechanism for the change in SHBG is not known, the increases in SHBG and reductions in insulin as a result of this lifestyle intervention should reduce the risk for breast cancer in postmenopausal women.
Fluvoxamine and clomipramine in depressed patients A DOUBLE‐BLIND CLINICAL STUDY

In a double‐blind study we compared fluvoxamine, a new selective serotonin re‐uptake inhibitor, with clomipramine. In 36 female in‐patients with vital depression, the antidepressant properties of fluvoxamine and clomipramine were studied. Eight patients did not complete the study.
Ensuring Cross-Cultural Equivalence in Translation of Research Consents and Clinical Documents

The aim of this article is to describe a formal process used to translate research study materials from English into traditional Chinese characters. This process may be useful for translating documents for use by both research participants and clinical patients. A modified Brislin model was used as the systematic translation process. Four bilingual translators were involved, and a Flaherty 3-point scale was used to evaluate the translated documents. The linguistic discrepancies that arise in the process of ensuring cross-cultural congruency or equivalency between the two languages are presented to promote the development of patient-accessible cross-cultural documents.
Refactoring

A common phenomenon to software systems is that of software entropy, which suggests that over time the design integrity of software decays under the accumulated pressure of modifications, enhancements, and bug fixes. Refactoring is a technique to stem and even reverse this process. This tutorial is an example driven introduction to refactoring: a disciplined approach to changing the design of an existing code base.
Validation of accelerometer data for measuring impacts during jumping and landing tasks

The purpose of this study was to examine the validity of a commercially-available accelerometer, as used in the field team sports context. Ten adult participants completed two movement tasks: 1) a drop landing task from 30-cm, 40-cm and 50-cm heights [DLAND], and 2) a countermovement jumping task [CMJ]. Peak acceleration values, both smoothed and unsmoothed, occurring in the longitudinal axis [Y] and calculated to produce vector magnitude values [VM], were compared to peak vertical ground reaction force values [VGRF]. All acceleration measures were moderately correlated (r = 0.45 – 0.70), but also significantly higher than weight-adjusted VGRF, for both tasks. Though the raw acceleration measures were mostly above the acceptable limit for error (> 20%), the smoothed data had reduced error margins by comparison, most of which were well below 20%. These results provide some support for the continued use of accelerometer data, particularly when smoothed, to accurately quantify impacts in the field.
A BiCMOS implementation of noise canceling low noise amplifier for wideband applications

We report in this paper a BiCMOS realization of the well-known noise canceling CMOS low noise amplifier first proposed in [1]. The ingenious design proposed in [1] features wonderful merits such as ultra-low noise, wideband and very good linearity. In order to achieve the noise cancelation point, a large amount of biasing current is needed in CMOS implementation. We design BiCMOS implementation of this famous noise canceling topology, which achieves significant biasing current reduction. Simulated in Tower Jazz 0. 18µm SiGe technology, the designed wideband LNA operates up to 5.2GHz with 17.5dB gain and dissipates about 10mA current from a single 1.8V supply. The simulated IIP3 is +5dBm with a noise figure of less than 2.5dB when matched to 50Ω and the chip layout area is less than 0.3mm2 excluding pads.
Hierarchical Clustering Algorithm based on Attribute Dependency for Attention Deficit Hyperactive Disorder

Attention Deficit Hyperactive Disorder (ADHD) is a disruptive neurobehavioral disorder characterized by abnormal behavioral patterns in attention, perusing activity, acting impulsively and combined types. It is predominant among school going children and it is tricky to differentiate between an active and an ADHD child. Misdiagnosis and undiagnosed cases are very common. Behavior patterns are identified by the mentors in the academic environment who lack skills in screening those kids. Hence an unsupervised learning algorithm can cluster the behavioral patterns of children at school for diagnosis of ADHD. In this paper, we propose a hierarchical clustering algorithm to partition the dataset based on attribute dependency (HCAD). HCAD forms clusters of data based on the high dependent attributes and their equivalence relation. It is capable of handling large volumes of data with reasonably faster clustering than most of the existing algorithms. It can work on both labeled and unlabelled data sets. Experimental results reveal that this algorithm has higher accuracy in comparison to other algorithms. HCAD achieves 97% of cluster purity in diagnosing ADHD. Empirical analysis of application of HCAD on different data sets from UCI repository is provided.