Miracle-dz/UniFAR-FTUs huggingface dataset:
Physical activity for the affected limb and arm lymphedema after breast cancer surgery. A prospective, randomized controlled trial with two years follow-up

Background. The influence of physical activity on the development of arm lymphedema (ALE) after breast cancer surgery with axillary node dissection has been debated. We evaluated the development of ALE in two different rehabilitation programs: a no activity restrictions (NAR) in daily living combined with a moderate resistance exercise program and an activity restrictions (AR) program combined with a usual care program. The risk factors associated with the development of ALE 2 years after surgery were also evaluated. Material and methods. Women (n = 204) with a mean age of 55±10 years who had axillary node dissection were randomized into two different rehabilitation programs that lasted for 6 months: NAR (n = 104) or AR (n = 100). The primary outcomes were the difference in arm volume between the affected and control arms (Voldiff, in ml) and the development of ALE. Baseline (before surgery) and follow-up tests were performed 3 months, 6 months, and 2 years after surgery. Data were analyzed using ANCOVA and regression analysis. Results. Voldiff did not differ significantly between the two treatment groups. Arm volume increased significantly over time in both the affected and the control arms. The development of ALE from baseline to 2 years increased significantly in both groups (p < 0.001). The only risk factor for ALE was BMI > 25 kg/m2. Conclusion. Patients that undergo breast cancer surgery with axillary lymph node dissection should be encouraged to maintain physical activity in their daily lives without restrictions and without fear of developing ALE.
Social Network Circle Discovery Using Latent Dirichlet Allocation

Online Social Networks, such as Facebook, provide a great interface for connecting with others, whether they are acquaintances or close friends. However, there is no distinction made between different social circles, or clusters of friends who share some common feature(s). In this paper, we explore ways to apply Latent Dirichlet Allocation (LDA), an unsupervised learning algorithm traditionally used for topic detection in textual corpora, to automatically detect social circles among a subject’s friends. For each friend, which we will consider as documents, we take in account both the profile features and users’ friends, comparable to word ”tokens. ” Finally, we will analyze our results by finding the cost-minimizing assignment from our circles to the groundtruth circles, based on the Balanced Error Rate (BER).
A pr 2 00 3 The Host Galaxies of AGN

We examine the properties of the host galaxies of 22,623 narrow-line AGN with 0.02 < z < 0.3 selected from a complete sample of 122,808 galaxies from the Sloan Digital Sky Survey. We focus on the luminosity of the [OIII]λ5007 emission line as a tracer of the strength of activity in the nucleus. We study how AGN host properties compare to those of normal galaxies and how they depend on L[OIII]. We find that AGN of all luminosities reside almost exclusively in massive galaxies and have distributions of sizes, stellar surface mass densities and concentrations that are similar to those of ordinary early-type galaxies in our sample. The host galaxies of low-luminosity AGN have stellar populations similar to normal early-types. The hosts of high-luminosity AGN have much younger mean stellar ages. The young stars are not preferentially located near the nucleus of the galaxy, but are spread out over scales of at least several kiloparsecs. A significant fraction of high-luminosity AGN have strong Hδ absorptionline equivalent widths, indicating that they experienced a burst of star formation in the recent past. We have also examined the stellar populations of the host galaxies of a sample of broad-line AGN. We conclude that there is no significant difference in stellar content between type 2 Seyfert hosts and QSOs with the same [OIII] luminosity and redshift. This establishes that a young stellar population is a general property of AGN with high [OIII] luminosities.
Abstract Clustering for Program Comprehension

A new formal framework for program comprehension, Abstract Clustering, is presented. To manage the process of semantic-based modularisation of a software system from its source code, Abstract Interpretation is used to find a partition rather than measures. The result is a formal, semantic-based framework that offers a new approach to program comprehension.
Using local discriminant topic to improve generative model based image annotation

Statistical generative model based image annotation propagates the semantic labels of the training images to the unlabeled ones according to their visual generative probabilities. However, it suffers from the problem of "semantic gap", that is, sometimes visual similarity does not reflect semantic similarity. In order to alleviate this problem, we propose a novel image annotation approach which combines the advantages of the generative model and discriminative classification. Based on generative model, we exploit the local discriminants of the visual similar training images (neighborhood) of the unlabeled image. The semantic similar images in the neighborhood are grouped as topics by singular value decomposition (SVD). The discriminative information between different topics is exploited to obtain the semantic relevant topic, which reduces the influence of the images with high visual similarity but irrelevant semantics. Thus, the joint probability of the semantic keyword and the unlabeled image estimated on the obtained relevant topic is more accurate. The experimental results on the ECCV2002 benchmark (P. Duygulu et al., 2002) show that our method outperforms state-of-the-art annotation models MBRM and ASVM-MIL.
Probabilistic cutting plane technique based on maximum volume ellipsoid center

This paper presents a probabilistic cutting plane technique for solving a robust feasibility problem which is to find a solution satisfying a parameter-dependent convex constraint for all possible parameter values. The proposed algorithm employs random samples of the parameter and maximum volume ellipsoid centers of candidates of the solution set. It is shown that the numbers of updates and random samples are polynomials of the problem size. The algorithm is also extended for solving a robust optimization problem.
Embedded power supply for low-power DSP

The use of dynamically adjustable power supplies as a method to lower power dissipation in DSP is analyzed. Power can be reduced substantially without sacrificing performance in fixed-throughput applications by slowing the clock and lowering supply voltage instead of idling when computational workload varies. This can yield a typical power savings of 30-50%. If latency can be tolerated, buffering data and averaging processing rate can yield power reductions of an order of magnitude in some applications. Continuous variation of the supply voltage can be approximated by very crude quantization and dithering: a four-level controller is sufficient to get within a few percent of the optimal power savings. Significant savings are possible only if the voltage can be changed on the same time scale as the variations in workload. A chip has been fabricated and tested to verify the closed-loop functionality of a variable voltage system. The controller takes only 0.4 mm/sup 2/ and draws a maximum of 1 mW at 2 V with a 40 MHz clock. The control framework developed is applicable to generic DSP applications.
A leaping maneuvre for a brachiating robot

We report on a control strategy for the "leap" problem arising from an ape's fast brachiation when the next branch is far out of reach and the task involves a significant component of free flight as well as swing motion. In the swing phase, good regulation of velocity and angular momentum for lift-off to aim at the target bar is required. In the flight phase, control of the posture and rotation of the body is important to catch the bar. We propose a control strategy to achieve such a dynamic maneuver for a two degrees of freedom brachiating robot. Numerical simulations suggest that the proposed strategy achieves the desired leaping maneuver.
VAST: visualizing autonomous system topology

Extracting specific and relevant information regarding the Internet's BGP routing topology is a challenging task. In this paper we present a set of techniques that can be used to visualize various aspects of the Internet topology. We have implemented our visualization techniques in a unique tool called VAST (Visualizing Autonomous System Topology). With the help of simple illustrative examples we describe how our visualizations allow security researchers to extract relevant information quickly from raw BGP routing datasets. VAST provides visualizations that represent information about both the overall topological properties of the Internet as well as individual Autonomous System (AS) behavior.
The selective continued linkage of centromeres from mitosis to interphase in the absence of mammalian separase

Separase is an evolutionarily conserved protease that is essential for chromosome segregation and cleaves cohesin Scc1/Rad21, which joins the sister chromatids together. Although mammalian separase also functions in chromosome segregation, our understanding of this process in mammals is still incomplete. We generated separase knockout mice, reporting an essential function for mammalian separase. Separase-deficient mouse embryonic fibroblasts exhibited severely restrained increases in cell number, polyploid chromosomes, and amplified centrosomes. Chromosome spreads demonstrated that multiple chromosomes connected to a centromeric region. Live observation demonstrated that the chromosomes of separase-deficient cells condensed, but failed to segregate, although subsequent cytokinesis and chromosome decondensation proceeded normally. These results establish that mammalian separase is essential for the separation of centromeres, but not of the arm regions of chromosomes. Other cell cycle events, such as mitotic exit, DNA replication, and centrosome duplication appear to occur normally. We also demonstrated that heterozygous separase-deficient cells exhibited severely restrained increases in cell number with apparently normal mitosis in the absence of securin, which is an inhibitory partner of separase.
The Mouse RACK1 Gene Is Regulated by Nuclear Factor-κB and Contributes to Cell Survival

Receptor for activated C kinase 1 (RACK1) is a multifunctional, WD motif-containing protein important in regulating several cell surface receptors and intracellular protein kinases. To better understand its function, we cloned the mouse RACK1 gene and found it contains eight exons and seven introns, and maps to mouse chromosome 11B1.2-1.3. Promoter analysis identified NF-κB as an important transcription factor for promoter activity. In PC-12 cells, nerve growth factor (NGF), which activates nuclear factor-κB (NF-κB), maintained RACK1 levels and promoted cell survival in serum-free medium. Inhibitors of NF-κB activation blocked NGF-stimulated survival and RACK1 expression, whereas transgenic expression of RACK1 promoted survival in cells deprived of serum and NGF. Thus, RACK1 gene expression is induced by NF-κB and RACK1 contributes to NF-κB-mediated cell survival.
STEP, XML, and UML: Complementary Technologies1

One important aspect of product lifecycle management (PLM) is the computer-sensible representation of product information. Over the past fifteen years or so, several languages and technologies have emerged that vary in their emphasis and applicability for such usage. ISO 10303, informally known as the Standard for the Exchange of Product Model Data (STEP), contains the high-quality product information models needed for electronic business solutions. By using STEP, the aerospace, automotive, and ship building industries are saving $150M per year primarily in areas related to geometric modeling. However, traditional STEP-based model information is represented using languages that are unfamiliar to most application developers, thus impeding widespread usage in other areas. This paper discusses efforts underway to make STEP information models available via mechanisms familiar to more business application developers, specifically XML and the Unified Modeling Language™ (UML®). We also present a vision and roadmap for STEP integration with XML, UML, and other technologies to enable enhanced PLM interoperability. Our conclusion is that STEP, XML, and UML are complementary technologies, where STEP provides significant standardized content models, while XML and UML provide enhanced implementation methods. Together, they are a powerful force to enable pervasive digital representation and sharing of diverse technical information.
Performance driven multi-level and multiway partitioning with retiming

In this paper, we study the performance driven multiw ay circuit partitioning problem with consideration of the significant difference of local and global interconnect delay induced by the partitioning. We develop an efficient algorithm HPM (Hierarc hicalP erformance driven Multi-level partitioning) that simultaneously considers cutsize and delay minimization with retiming. HPM builds a multi-lev el cluster hierarc hy and performs various refinement while gradually decomposing the clusters for simultaneous cutsize and delay minimization. We provide comprehensive experimental justification for each step involv ed in HPM and in-depth analysis of cutsize and delay tradeoff existing in the performance driven partitioning problem. HPM obtains (i) 7% to 23% better delay compared to the state-of-the-art cutsize driven hMetis [11] at the expense of 19% increase in cutsize, and (ii) 81% better cutsize compared to the state-of-the-art delay driven PRIME [2] at the expense of 6% increase in delay.
Non-intrusive BIST for systems-on-a-chip

The term "functional BIST" describes a test method to control functional modules so that they generate a deterministic test set, which targets structural faults within other parts of the system. It is a promising solution for self-testing complex digital systems at reduced costs in terms of area overhead and performance degradation. While previous work mainly investigated the use of functional modules for generating pseudo-random and pseudo-exhaustive test patterns, the present paper shows that a variety of modules can also be used as a deterministic test pattern generator via an appropriate reseeding strategy. This method enables a BIST technique that does not introduce additional hardware like test points and test registers into combinational and pipelined modules under test. The experimental results prove that the reseeding method works for accumulator based structures, multipliers, or encryption modules as efficiently as for the classic linear feedback shift registers, and some times even better.
APDL: A Processor Description Language For Design Space Exploration of Embedded Processors

This paper presents Anahita Processor Description Language (APDL) for generation of retargetable processor design tool sets. The emphasis is on the applicability of the generated tools in the design space exploration (DSE) phase of designing a new embedded processor. APDL descriptions can be used for generating cycle-accurate instruction set simulators, assembler/disassembler tools, production quality compilers and architecture verification tools. The paper first investigates the features required for a language to be useful for DSE and then presents APDL constructs along with code samples.
Efficient Super-Resolution Up-Conversion Algorithm for HDTV

Video up-conversion takes significant place in various application areas. One of important application areas is standard-definition television (SDTV) video processing to get high-definition television content (HDTV) for broadcast. However, high-quality upconversion is a challenging task. Most practical implementations use spatial domain processing such as video frame interpolation for video up-scale. Meanwhile, due to sampling limitation the highfrequency component of output HD video cannot be efficiently reconstructed by applying only the spatial domain processing and high-quality up-conversion usually requires temporal domain processing as well. The authors propose practical implementation of such up-conversion technique providing significantly better visual results in comparison to traditional methods of SDTV to HDTV up-conversion.
Granulocyte colony‐stimulating factor mobilized whole blood containing over 0·3 × 106/kg CD34+ cells is a sufficient graft in autologous transplantation for relapsed non‐Hodgkin's lymphoma

Summary. The feasibility of unprocessed, granulocyte colony‐stimulating factor (G‐CSF)‐mobilized whole blood (WB) as an alternative stem cell source for autologous stem cell transplantation was studied. Forty‐seven relapsed non‐Hodgkin's lymphoma (NHL) patients entered the study. After two or three ifosfamide, methotrexate and etoposide (IMVP) courses, 1 l of G‐CSF‐mobilized WB was collected and stored refrigerated for 72 h. Meanwhile, BAM conditioning was given: BCNU (carmustine) 300 mg/m2, high‐dose cytarabine 6000 mg/m2 and melphalan 140 mg/m2. Toxicity, haematological recovery and survival were assessed and compared with peripheral blood stem cell transplantation (PBSCT) and bone marrow transplantation (BMT) reference groups. High‐dose G‐CSF (2 × 12 µg/kg/d) gave the best mobilization results. Haematological recovery was related to the WB CD34+ content. A CD34+ threshold of ≥ 0·3 106/kg, obtained in 90% of patients using high‐dose G‐CSF, correlated with adequate recovery: absolute neutrophil count (ANC) > 0·5 × 109/l: median 12 d (range 9–19). Platelet recovery > 20 and > 50 × 109/l was 19 (11–59) and 30 d (14 not reached) respectively. Overall survival of patients < 60 years was 57% at 4 years and event‐free survival was 32%. Survival was comparable with PBSCT and BMT after BEAM (BCNU, etoposide, cytarabine, melphalan). Remarkably, haematological recovery after BAM + WB was rapid and comparable (ANC) or slightly prolonged (platelets) in comparison with BEAM + PBSCT, despite a 10–20 times lower CD34+ cell dose in the WB graft. In conclusion, transplantation of WB containing ≥ 0·3 × 106/kg CD34+ cells after BAM conditioning is a safe procedure, and offers a fully equivalent and less costly alternative for PBSC.
PPG: online generation of protein pictures and animations

The protein picture generator (PPG) is an online service to generate pictures of a protein structure. Its design was conceived as an answer to the need expressed by a part of the community to have some means to produce simply complex pictures to insert in publications or in presentations. PPG can produce static or animated pictures. It can be accessed at .
Usability versus Adaption - Approaches to Higher Level Context Detection

While the research in detection of context features even cognitive ones like the user’s goal steps forward continuously, it is often focused on the quality of detection. But since context often finds use in context adaptive systems that proactively adapt to the user’s need, research should always consider the resulting benefit of context for the user in any context-based application. This paper presents the results of a case study which a) evaluates algorithms to detect three subtypes of user goals in knowledge work and b) focuses on useability issues, that have a direct impact for a measurable improvement of the work results. Our work includes a quantitative evaluation like task completion time improvement and qualitative aspects (e.g. intrusiveness of the system). Finally, we draw conclusions from our measurements, especially on how modeling of an adaptive approach at the workplace might take place.
Microfluidic production of stem-cell microcapsules for spinal cord injury repair

Stem cell therapy demonstrates much promise for the replacement of damaged tissue in several diseases, including spinal cord injury. However, challenges around the control of stem cell fate in situ still hinders effective recovery of the normal tissue function. Stem cell encapsulation permits their immobilization within biocompatible scaffolds, allowing for a better control of parameters such as proliferation, integration, migration and differentiation within the host tissue. A customized microfluidic device was developed for the production of alginate microcapsules. The diameter of such microcapsules could be easily controlled by the modification of the fluids flow rates, allowing for the reproducible production of highly monodisperse microcapsules. This microfluidic method was then successfully applied for the encapsulation of two different types of stem cells: (i) Neural Stem Cells and (ii) Dental Pulp Stem Cells. Both cell types demonstrated survival within the alginate microcapsules for up to three weeks in culture. However, an early egress of cells from inside to outside of the microcapsules was observed 3 days post-encapsulation. In order to delay such cell escape, alginate microcapsules were modified through the addition of type I collagen. The alginate-collagen microcapsules permitted similar rates of cell survival and permitted the delay of cell egress until 10 days after encapsulation. Stem cells demonstrated a retention of their stem cell and neuronal differentiation properties upon selective release from alginate-collagen microcapsules, as demonstrated by high proliferation rates and the production of stem cell and neuronal markers. When cell-laden microcapsules were transplanted into an ex vivo SCI model the microcapsules were able to effectively retain the transplanted stem cells at the site of implantation. Transplanted cells survived up to 10 days in culture after transplantation and demonstrated the production of neuronal markers within the cord cultures. The results presented in this thesis demonstrate the ability of stem cells to retain their viability and neuronal differentiation capacity within alginate-collagen microcapsules, thereby providing a promising future therapy for the treatment of spinal cord injury.
Software Behavior Trustworthiness Detection Based on PrefixSpan Method

Current study of Trusted Computing is mainly about TCP and it is not effective to check trustworthiness of software behavior. With analysis of current detection technique, a static detection method towards software behavior trustworthiness is proposed and its key technique is discussed. First, Malware code is disassembled and preprocessed into sequential data, second, a Prefix Span-based algorithm is used to discover frequent sequential pattern and remove normal pattern, at last, the result pattern set can be used to detect target software and give results about its behavior trustworthiness. Test result indicates that the method has high accuracy rate and low false positive rate.
The role of gait analysis in clinical medicine: a survey of UK centres.

This paper reports the results of a survey carried out to assess the clinical usage currently being made of gait analysis facilities within the UK.Thirty-five centres were circulated with a questionnaire which requested information under four main headings: (i) equipment, (ii) research projects, (iii) clinical service commitments, and (iv) subjective views of the ultimate clinical value of the service. Of the 25 completed questionnaires returned, 16 were suitable for inclusion in the final analysis of data.The survey provided useful data on the equipment and facilities available in each centre together with details of the service available to prospective referring clinicians. Ten centres were considered as being currently involved in some clinical work, with six of these being routinely involved.The respondents generally felt that gait analysis techniques have a clinical context, if not yet routinely, but the numbers of referrals to the centres is still quite small. A number of areas worthy of further wor.