Miracle-dz/UniFAR-FTUs huggingface dataset:
The Persistence of Classically Conditioned Brand Attitudes

Abstract The researchers investigated the long-term effects of classically conditioned attitudes toward a brand. In two experiments, subjects were exposed to classical conditioning procedures in which favorable images were paired with a fictitious brand of mouthwash. Study 1, a within-subjects design, examined attitudes of a single subject pool immediately after exposure, after a one-week delay, and after a three-week delay. In study 2, the same methods and procedures were used to condition favorable responses to the test brand, but a between-subjects design was used to control for possible measurement effects. Measurements were taken immediately after exposure to conditioning trials for one group of subjects and three weeks after exposure to the trials for a second group. Results from both studies support the hypothesis that attitudes formulated through classical conditioning are enduring.
Conditional CycleGAN for Attribute Guided Face Image Generation

State-of-the-art techniques in Generative Adversarial Networks (GANs) such as cycleGAN is able to learn the mapping of one image domain $X$ to another image domain $Y$ using unpaired image data. We extend the cycleGAN to ${\it Conditional}$ cycleGAN such that the mapping from $X$ to $Y$ is subjected to attribute condition $Z$. Using face image generation as an application example, where $X$ is a low resolution face image, $Y$ is a high resolution face image, and $Z$ is a set of attributes related to facial appearance (e.g. gender, hair color, smile), we present our method to incorporate $Z$ into the network, such that the hallucinated high resolution face image $Y'$ not only satisfies the low resolution constrain inherent in $X$, but also the attribute condition prescribed by $Z$. Using face feature vector extracted from face verification network as $Z$, we demonstrate the efficacy of our approach on identity-preserving face image super-resolution. Our approach is general and applicable to high-quality face image generation where specific facial attributes can be controlled easily in the automatically generated results.
Two Color DNA Barcode Detection in Photoluminescence Suppressed Silicon Nitride Nanopores

Optical sensing of solid-state nanopores is a relatively new approach that can enable high-throughput, multicolor readout from a collection of nanopores. It is therefore highly attractive for applications such as nanopore-based DNA sequencing and genotyping using DNA barcodes. However, to date optical readout has been plagued by the need to achieve sufficiently high signal-to-noise ratio (SNR) for single fluorophore sensing, while still maintaining millisecond resolution. One of the main factors degrading the optical SNR in solid-state nanopores is the high photoluminescence (PL) background emanating from the silicon nitride (SiNx) membrane in which pores are commonly fabricated. Focusing on the optical properties of SiNx nanopores we show that the local membrane PL intensity is substantially reduced, and its spectrum is shifted toward shorter wavelengths with increasing e-beam dose. This phenomenon, which is correlated with a marked photocurrent enhancement in these nanopores, is utilized to perform for the first time single molecule fluorescence detection using both green and red laser excitations. Specifically, the reduction in PL and the concurrent measurement of the nanopore photocurrent enhancement allow us to maximize the background suppression and to detect a dual color, five-unit DNA barcode with high SNR levels.
ANTHEPROT: a package for protein sequence analysis using a microcomputer

A simple microcomputer package is described to make the theoretical analysis of protein sequences. Several methods designed to compare two sequences, to model proteolytic reactions and to predict the secondary structure, the hydrophobic/hydrophilic regions and the potential antigenic sites of proteins have been included in an Apple II microcomputer software. The package comprises 21 programs as well as the secondary structure database of Kabsch and Sander (1983).
Comparative abilities of Microsoft Kinect and Vicon 3D motion capture for gait analysis

Abstract Biomechanical analysis is a powerful tool in the evaluation of movement dysfunction in orthopaedic and neurologic populations. Three-dimensional (3D) motion capture systems are widely used, accurate systems, but are costly and not available in many clinical settings. The Microsoft Kinect™ has the potential to be used as an alternative low-cost motion analysis tool. The purpose of this study was to assess concurrent validity of the Kinect™ with Brekel Kinect software in comparison to Vicon Nexus during sagittal plane gait kinematics. Twenty healthy adults (nine male, 11 female) were tracked while walking and jogging at three velocities on a treadmill. Concurrent hip and knee peak flexion and extension and stride timing measurements were compared between Vicon and Kinect™. Although Kinect measurements were representative of normal gait, the Kinect™ generally under-estimated joint flexion and over-estimated extension. Kinect™ and Vicon hip angular displacement correlation was very low and error was large. Kinect™ knee measurements were somewhat better than hip, but were not consistent enough for clinical assessment. Correlation between Kinect™ and Vicon stride timing was high and error was fairly small. Variability in Kinect™ measurements was smallest at the slowest velocity. The Kinect™ has basic motion capture capabilities and with some minor adjustments will be an acceptable tool to measure stride timing, but sophisticated advances in software and hardware are necessary to improve Kinect™ sensitivity before it can be implemented for clinical use.
Version unknown SOURCE ( OR PART OF THE FOLLOWING SOURCE ) : Type article Title Repolarisation and refractoriness during early ischaemia in humans

Objectives—To determine whether eVective refractory period (ERP) shortens or lengthens in the first minutes of ischaemia in humans, and the relation between ERP changes and action potential duration (APD). Methods—ERP and monophasic action potential duration (MAPD) were measured from a single left ventricular epicardial site in 26 patients undergoing coronary artery surgery. Cardiopulmonary bypass was instituted and normothermia maintained. Refractory period was determined by the extrastimulus technique at a basic cycle length of 500 ms, at four times (group 1, 15 patients) or two times (group 2, 11 patients) the preischaemic diastolic threshold. A three minute period of ischaemia was instituted by aortic cross clamping between the input from the pump oxygenator and the heart. Results—After three minutes of ischaemia, mean (SEM) ERP lengthened from 232 (5) ms (control) to 246 (7) ms (p < 0.005) in group 1, and from 256 (10) ms (control) to 348 (25) ms (p < 0.005) in group 2. In the same time MAPD shortened from 256 (5) ms (control) to 189 (9) ms (p < 0.001) with no diVerence between groups. Thus postrepolarisation refractoriness developed during ischaemia. Before ischaemia, ERP showed a good correlation with APD (R = 0.64) but by one minute of ischaemia the correlation was poor (R = 0.29). Conclusions—These results show that during the first three minutes of global ischaemia in patients with coronary artery disease: (1) ERP lengthened in response to both a low and a high stimulus strength; and (2) there was a good correlation between ERP and APD before ischaemia, which was lost by one minute as APD decreased and ERP increased. These findings may have important implications in arrhythmogenesis. (Heart 2000;84:365–369)
On the User-Centric Connection Availability of Mobile Wireless Networks

In this paper we study the connection availability of wireless networks from the perspective of end users with individual mobility, in contrast to existing studies mainly focusing on network-centric connectivity. Specifically, we evaluate the user connectivity by two metrics: neighbor connection time and neighbor isolation time. The former is the time for a node being connected with at least one neighbor; while the latter is the time for a node being isolated before it is connected to new neighbors. By using the theory of Markov renewal process, we obtain the asymptotic bounds on the expected neighbor connection and isolation times, which are dependent on the node density, transmission range, and average speed.We find that if the network is super-critical, implying the existence of a unique giant (connected) component, both asymptotic bounds scale with the number of nodes in the network; otherwise, expected connection and isolation times are constant.
Mechanical Properties of Nanoporous Au: From Empirical Evidence to Phenomenological Modeling

The present work focuses on the development of a theoretical model aimed at relating the mechanical properties of nanoporous metals to the bending response of thick ligaments. The model describes the structure of nanoporous metal foams in terms of an idealized regular lattice of massive cubic nodes and thick ligaments with square cross-sections. Following a general introduction to the subject, model predictions are compared with Young’s modulus and the yield strength of nanoporous Au foams determined experimentally and available in literature. It is shown that the model provides a quantitative description of the elastic and plastic deformation behavior of nanoporous metals, reproducing to a satisfactory extent the experimental Young’s modulus and yield strength values of nanoporous Au.
Transitions: A Mental Health Literacy Program for Postsecondary Students

Enhancement of mental health literacy is a mental health promotion strategy that may be effective at destigmatizing mental illness and increasing self-seeking behavior. Transitions is a mental health literacy program intended to heighten students' awareness and discussion of mental health problems and promote help-seeking behaviors. Transitions was launched in Nova Scotia in 2007 and distributed to 8,000 students. Transitions has since been launched nationally and is in the process of launching internationally. A follow-up study indicated over 95% of students felt they could relate to Transitions and enjoyed reading it, and 40% discussed Transitions with a friend.
Atom guiding along high order Laguerre–Gaussian light beams formed by spatial light modulation

A spatial light modulator (SLM) has been used to create high quality Laguerre–Gaussian (LG) light beams, which have been used to study the guiding of cold rubidium atoms. The SLM allows real-time variation of the hollow guiding beam and permits direct comparison of the guided atom fluxes for different LG modes with minimal adjustment of the other optical components. It is demonstrated that, by increasing the azimuthal index l of the Laguerre–Gaussian beam, the radiation pressure pushing the trapped atoms may be reduced while maintaining the same guided flux. This is the first comparative study of hollow beam atom guiding, and further demonstrates the versatility of the SLM for studies in atom optics.
Healthy Lifestyle and Leukocyte Telomere Length in U.S. Women

Context Whether a healthy lifestyle may be associated with longer telomere length is largely unknown. Objectives To examine healthy lifestyle practices, which are primary prevention measures against major age-related chronic diseases, in relation to leukocyte telomere length. Design and Setting Cross-sectional analysis in the Nurses' Health Study (NHS). Participants The population consisted of 5,862 women who participated in multiple prospective case-control studies within the NHS cohort. Z scores of leukocyte telomere length were derived within each case-control study. Based on prior work, we defined low-risk or healthy categories for five major modifiable factors assessed in 1988 or 1990: non-current smoking, maintaining a healthy body weight (body mass index in 18.5–24.9 kg/m2), engaging in regular moderate or vigorous physical activities (≥150 minutes/week), drinking alcohol in moderation (1 drink/week to <2 drinks/day), and eating a healthy diet (Alternate Healthy Eating Index score in top 50%). We calculated difference (%) of the z scores contrasting low-risk groups with reference groups to evaluate the association of interest. Results Although none of the individual low-risk factors was significantly associated with larger leukocyte telomere length z scores, we observed a significant, positive relationship between the number of low-risk factors and the z scores. In comparison with women who had zero low-risk factors (1.9% of the total population) and were, therefore, considered the least healthy group, the leukocyte telomere length z scores were 16.4%, 22.1%, 28.7%, 22.6%, and 31.2% (P for trend = 0.015) higher for women who had 1 to 5 low-risk factors, respectively. Conclusions Adherence to a healthy lifestyle, defined by major modifiable risk factors, was associated with longer telomere length in leukocytes.
There are more things in heaven and earth than are dreamed of in BMT: A response to Jacobson.

This article is a reply to Jacobson's article in which he critiques the Snyder and Wills study comparing behavioral and insight-oriented interventions as well as the 4-year follow-up of this study, and makes suggestions as to the implications of these studies for future marital therapy research. This article suggests that therapist competence is not a fruitful line of enquiry for future research, and that although we agree that manualization is an issue, manuals must include more than simple therapist behaviors. We also agree that there is a need to focus on the process of change in marital therapy. However, the crucial issue, from our perspective, is that interventions be clearly linked to theoretical formulations concerning the nature of relationships and the nature of marital distress, so that the differences between different interventions and approaches to marital therapy can be clearly differentiated
Structural basis for nuclear receptor corepressor recruitment by antagonist-liganded androgen receptor

Androgen receptor (AR) recruitment of transcriptional corepressors NCoR and SMRT can be enhanced by antagonists such as mifepristone. This study shows that enhanced NCoR binding to the mifepristone-liganded AR is mediated by the NCoR COOH-terminal N1 CoRNR box and that this selectivity is due to charged residues unique to the COOH-terminal CoRNR boxes of NCoR and SMRT. Significantly, these residues are on a helical face adjacent to oppositely charged residues in helix 4 of the AR ligand-binding domain. Mutagenesis of these AR residues in helix 4, as well as mutation of lysine 720 in helix 3 (predicted to interact with the CoRNR box), markedly impaired AR recruitment of NCoR, indicating that N1 CoRNR box binding is being stabilized by these ionic interactions in the AR ligand-binding domain coactivator/corepressor binding site. Finally, results using a helix 12–deleted AR indicate that mifepristone induces allosteric changes in addition to helix 12 displacement that are critical for NCoR binding. These findings show that AR antagonists can enhance corepressor recruitment by stabilizing a distinct antagonist conformation of the AR coactivator/corepressor binding site and support the development of additional antagonists that may be able to further enhance AR recruitment of corepressors. [Mol Cancer Ther 2008;7(10):3187–94]
Interleukin (IL)-6 and Its Soluble Receptor Induce TIMP-1 Expression in Synoviocytes and Chondrocytes, and Block IL-1-induced Collagenolytic Activity*

To define the potential role of interleukin-6 (IL-6) and its soluble receptor α in cartilage metabolism, we analyzed their effects on tissue inhibitor of metalloproteases (TIMP) synthesis by synoviocytes and chondrocytes. TIMP-1 production by isolated human articular synovial fibroblasts and chondrocytes, stimulated by IL-6 and/or its soluble receptor, was first assayed by specific enzyme-linked immunosorbent assay; the slight stimulatory effect of IL-6 on TIMP-1 production by both types of cells was markedly amplified by the addition of soluble receptor, the maximal secretion being observed only at 96 h. TIMP-1 mRNA expression, determined by ribonuclease protection assay, was induced by IL-6 together with its soluble receptor, but TIMP-2 and -3 mRNAs were not affected by these factors. A specific neutralizing antibody abolished the effects of the soluble receptor. Finally, supernatant from synoviocytes stimulated by IL-6 plus its soluble receptor blocked almost completely the collagenolytic activity of supernatant from IL-1-induced synoviocytes. These observations indicate that IL-6 and its soluble receptor have a protective role in the metabolism of cartilage. Given the high levels of soluble receptor in synovial fluid and the marked induction of IL-6 by IL-1 or TNF-α, it is likely that IL-6 and its soluble receptor are critical in controlling the catabolic effects of pro-inflammatory cytokines.
Narcissism and Defending Self-Esteem. An Exploratory Study based on Self-characterizations

The present qualitative study aims at investigating the role of socio-relational variables in the construction of threats to self-esteem, grandiosity, and relaxation in a non-clinical sample of 35 young university students. The work provides fresh experimental evidence of the structural analogy observed in clinical settings between constructions of threat to self-esteem and grandiose fantasies. We hypothesize that the relational dimension would be more strongly present than either biological or psychological dimensions.The results show that descriptions of relaxation differ significantly from their characterizations of the other two domains. Specifically we found greater continuity and narrative connection between the aspects of threat and grandiosity, while the domain of relaxation showed a more "isolated" pattern.
CS 229 Project Report : Improving Search Engine For A Digital Library

This project introduces a novel approach for using click through data to discover clusters of similar queries and similar URLs. One can simply observe that users reformulate their queries to find a desirable result. We define this sequence of queries as a query chain. Our data set consists of records containing user id, query term, query date and time, clicked item URL and clicked item rank if there exists one. Viewing this data set as a bipartite graph we perform a graph-based agglomerative clustering to find similar queries and similar URLs. We intend to use human intelligence in expressing his information need as a prior knowledge in agglomerative clustering which will result in an earlier convergence and a noticeable improvement in whole system performance. We also describe how to validate this model and how to use query-URL clusters in a real-world search engines.
The PDBFINDER database: a summary of PDB, DSSP and HSSP information with added value

MOTIVATION The Protein Data Bank currently contains more than 4700 protein coordinate sets. It is often desirable to make a selection from these files based on a criterion like R-factor, experimental method, length of the amino acid sequence, or the number of homologous sequences in SWISSPROT. Doing this using the distributed form of the Protein Data Bank can be a tedious task, because (1) this requires reading one file for every single entry, and (2) not all of the information is present in a consistent computer readable way in all of the entries. RESULTS The PDBFINDER database provides an easy to interpret file containing summary information about all Protein Data Bank files. Summary information from the DSSP (Definition of Secondary Structure of Proteins) and HSSP (Homology derived Secondary Structure of Proteins) databases is also included. Furthermore, where essential data were missing from the Protein Data Bank file, this information has been retrieved from the original literature. AVAILABILITY The latest version of the PDBFINDER database can be downloaded by anonymous ftp from swift.embl-heidelberg.de, directory:/pdbfinder. CONTACT E-mail address hooft@embl-heidelberg.de.
Testing Zimbardo’s Stanford Time Perspective Inventory (STPI) - Short Form

In the present study the psychometric properties of the Stanford Time Perspective Inventory (STPI - short version) are assessed in an Italian sample. Factorial analysis of STPI items was performed on 1507 respondents (965 women and 542 men). Results showed a clear correspondence between factorial components and a priori hypothesized dimensions by evidencing three factors (Future, Hedonistic Present, Fatalistic Present). Italian translation of the STPI indicates a fair degree of internal consistency and good metrological characteristics. The present results parallel those previously reported for an American sample. The present study, however, failed in evidencing the ‘Past’ as a factor in the factor structure. The results are discussed in terms of individual differences with respect to the relationships between demographic variables and temporal dimensions.
Deconstructing the meerkat: fabular anthropomorphism, popular culture, and the market

Abstract In this paper we attempt to create an understanding of fabular anthropomorphism of particular relevance to marketing communication. Through an examination of the religious, anthropological, rhetorical and marketing literature on personification and anthropomorphism we arrive at six principles that characterise the use of animals as symbols in instructional storytelling. We then examine the applicability of these principles by investigating the way in which meerkats have recently been used in popular culture and marketing communication. We find that our proposed definition of a marketing-orientated fabular anthropomorphism is broadly applicable and is helpful in understanding why certain anthropomorphic depictions will resonate with audiences and others will not. Summary statement of contribution This research proposes a set of principles that help us to understand the way in which fabular instantiations of anthropomorphism can be successfully used in marketing communication. It presents a case study that demonstrates the applicability of the findings.
Prescription of Benzodiazepines and Related Drugs in Patients with Mild Cognitive Deficits and Alzheimer’s Disease

Abstract Introduction Benzodiazepines and related drugs (BZDR) should be avoided in patients with cognitive impairment. We evaluated the relationship between a BZDR treatment and the health status of patients with Alzheimer’s disease (AD). Methods Cross-sectional study in 395 AD patients using bivariate and multiple logistic analyses to assess correlations between the prescription of BZDR and patients’ characteristics (cognitive and functional capacity, health-related quality of life (HrQoL), neuropsychiatric symptoms). Results BZDR were used in 12.4% (n=49) of all participants. In bivariate analyses, the prescription was associated with a lower HrQoL, a higher need of care, and the presence of anxiety. Multivariate models revealed a higher risk of BZDR treatment in patients with depression (OR 3.85, 95% CI: 1.45 – 10.27). Community-dwelling participants and those treated by neurologists/psychiatrists had a lower risk of receiving BZDR (OR 0.33, 95% CI: 0.12 – 0.89 and OR 0.16, 95% CI: 0.07 – 0.36). Discussion The inappropriate use of BZDR conflicts with national and international guidelines. We suggest evaluating indications and treatment duration and improving the knowledge of alternative therapies in healthcare institutions.