Miracle-dz/UniFAR-FTUs huggingface dataset:
Ground state of N=Z doubly closed shell nuclei in CBF theory

~Received 6 October 1997! The ground state properties of N5Z doubly closed shell nuclei are studied within correlated basis function theory. A truncated version of the Urbana v 14 realistic potential, with spin, isospin, and tensor components, is adopted, together with state-dependent correlations. Fermi hypernetted chain integral equations are used to evaluate the density, distribution function, and ground state energy of 16 O and 40 Ca. The nuclear matter single operator chain approximation is extended to finite nuclear systems, to deal with the noncommuting part of the correlation operators. The results favorably compare with variational Monte Carlo estimates, when available, and provide a first substantial check of the accuracy of the cluster summation method for state-dependent correlations. We achieve in finite nuclei a treatment of noncentral interactions and correlations having, at least, the same level of accuracy as in nuclear matter. This opens the way for a microscopic study of the medium heavy nuclei ground state using present day realistic Hamiltonians. @S0556-2813~98! 00104-6#
Notice of RetractionVibration analysis of a rotor with two open cracks

A finite element model is used for flexural vibration analysis of a static (non-rotating) rotor with two open cracks, and the stiffness matrices of the cracked elements are obtained using transfer matrix analysis and local flexibility theorem. Through numerical simulation, the effects of the slenderness ratio and the crack depth on the mode shapes and the changes in the eigenfrequencies of the cracked rotor are investigated, and the ratios of the changes in the first two eigenfrequencies are discussed for rotors with shallow cracks. The variations of the changes in eigenfrequencies with crack location are studied. Numerical results obtained are helpful for identification of cracked rotor.
An Improved Current Bleeding Mixer Based on CMOS Technology

An improved current bleeding CMOS mixer is designed in this paper. The conversion gain of the mixer is increased and the flicker noise of the mixer is reduced by inserting the inductor to form resonant circuit with parasitic capacitors of the source ports of the switch transistors in Gilbert mixer. The mixer is designed by using SMIC 0.18 um CMOS process. The simulated results show that the mixer proposed has a 1.76dB increase of conversion gain, 2.1dBm improvement of IIP3, 0.5dB decrease of noise figure with local power of -3 dBm as compared with the mixer before inserting the inductor
Hand Tracking Algorithm Based on SuperPixels Feature

There have been considerable research efforts to use the hand as an input device for HCI in recent years. Hand tracking is the most important procedure for HCI, it is essential of tracking stability and efficiency for hand manipulation. This paper proposed a novel hand tracking algorithm which can track a hand stable and is real time, and the proposed algorithm can work on normal CCD cameral. Our algorithm is based on mean-shift and we improved it to fit for robust hand tracking by using super pixel cluster, integrated GIH and skin color mask, the skin color mask was extracted using online learning. The proposed improved algorithm can track hand reliably even in clutter environments comparing to the existing traditional algorithms.
A maps-based angular PDF for navigation systems in indoor and outdoor environments

By incorporating known floor-plans in sequential Bayesian positioning estimators such as Particle Filters (PF), long term positioning accuracy can be achieved as long as the map is sufficiently accurate and the environment sufficiently constraints pedestrians' motion. Instead of using binary decisions to eliminate particles when crossing a wall as several authors do, a maps-based angular probability density function (PDF) is used in this paper that is capable of weighting the possible headings of the pedestrian according to local infrastructure. We will show that the angular PDF will help to obtain better performance in critical multi-modal navigation scenarios.
Left Cardiac Sympathetic Denervation in Long QT Syndrome: Analysis of Therapeutic Nonresponders

Background—Long QT syndrome (LQTS) is a potentially lethal but highly treatable cardiac channelopathy. Treatment options include pharmacotherapy, device therapy, and left cardiac sympathetic denervation (LCSD). Here, we sought to determine the characteristics of LQTS patients who have had ≥1 LQTS-related breakthrough cardiac event (BCE) after LCSD. Methods and Results—We performed retrospective chart review for 52 consecutive patients (24 males; mean age at diagnosis, 10.0±10 years; mean QTc, 528±74 ms) with LQTS who underwent LCSD between 2005 and 2010 (mean age at LCSD, 14.1±10 years) and have been followed up for 3.6±1.3 years. A BCE was defined as either (1) an appropriate ventricular fibrillation-terminating implantable cardioverter defibrillator shock or (2) arrhythmogenic syncope, seizures, or aborted cardiac arrest after LCSD. Thirty-three patients (61%) had LCSD as primary prevention because of either high-risk assessment or &bgr;-blocker intolerance. So far, 12 of 52 (23%) patients (7 males) have experienced ≥1 BCE post LCSD. The clinical phenotype of patients with BCEs was significantly more severe than patients without a BCE. No BCEs were seen in patients undergoing LCSD for &bgr;-blocker intolerance (0/12 versus 17/40; P<0.001). Conclusions—Although a marked reduction in number of cardiac events is usually seen after LCSD, ≈50% of high-risk LQTS patients have experienced ≥1 post-LCSD breakthrough. Therefore, LCSD must not be viewed as curative or as an alternative in implantable cardioverter defibrillator for high-risk patients. Prophylactic LCSD may provide another option to counter a suboptimal quality of life resulting from medication-related side effects.
Managing Complexity with the Department of Defense Architecture Framework: Development of a Dynamic System Architecture Model

Architecture frameworks are tools for managing system complexity by structuring data in a common language and format. By characterizing the form, function, and rules governing systems, architecture frameworks serve as a communication tool to stakeholder communities with different views of the system and facilitate comparative evaluation across architectures. The goal of this research is to explore the applicability of architecture frameworks to the study of emergent properties of satellites. The U.S. Department of Defense Architecture Framework was selected to achieve this goal given its orientation towards technical systems in contrast to the majority of architecture frameworks focused on business enterprises. Although developed by military planners in the 1990’s to support the acquisition of interoperable information systems, the Department of Defense Architecture Framework can be used to connect operational concepts and capabilities to the technical architecture of any system. While the views of the Department of Defense Architecture Framework are well-defined, little guidance is provided on how the views are to be constructed. Vitech Corporation’s software program CORE, ® a systems engineering modeling tool with the ability rapidly to produce architecture views from a common data repository, was employed to complete Department of Defense Architecture Frameworks for the Hubble Space Telescope. Upon characterizing Hubble within this common structure, the value of the Department of Defense Architecture Framework for conducting dynamic quantitative analyses of system architectures was explored. A methodology is proposed and tested for evaluating human and robotic architectures for on-orbit servicing—the extension of the useful life of spacecraft through refueling, upgrading, repair, relocation, et al. In particular, a multi-year servicing campaign is modeled for Hubble including behavioral threads that characterize the Orbiting Observatory, servicing architecture, and science customers. Preliminary results indicate that, when coupled
Mesothelial cell gene therapy

(57) Abstract: The methods and pharmaceutical compositions for modifying the mammalian recipient mesothelial cells in situ is provided. The method includes forming a mesothelial cell expression system in vivo or ex vivo, and administering the expression system to the mammalian recipient (on a normal state via a body cavity mesothelial cells are aligned) including. The mesothelial cell expression system is useful for topical and systemic transport in situ therapeutic agents.
Fast Effects of Glucocorticoids on Memory‐Related Network Oscillations in the Mouse Hippocampus

Transient or lasting increases in glucocorticoids accompany deficits in hippocampus‐dependent memory formation. Recent data indicate that the formation and consolidation of declarative and spatial memory are mechanistically related to different patterns of hippocampal network oscillations. These include gamma oscillations during memory acquisition and the faster ripple oscillations (approximately 200 Hz) during subsequent memory consolidation. We therefore analysed the effects of acutely applied glucocorticoids on network activity in mouse hippocampal slices. Evoked field population spikes and paired‐pulse responses were largely unaltered by corticosterone or cortisol, respectively, despite a slight increase in maximal population spike amplitude by 10 μm corticosterone. Several characteristics of sharp waves and superimposed ripple oscillations were affected by glucocorticoids, most prominently the frequency of spontaneously occurring sharp waves. At 0.1 μm, corticosterone increased this frequency, whereas maximal (10 μm) concentrations led to a reduction. In addition, gamma oscillations became slightly faster and less regular in the presence of high doses of corticosteroids. The present study describes acute effects of glucocorticoids on sharp wave‐ripple complexes and gamma oscillations in mouse hippocampal slices, revealing a potential background for memory deficits in the presence of elevated levels of these hormones.
Phenylglycine and Sulfonamide Correctors of Defective ΔF508 and G551D Cystic Fibrosis Transmembrane Conductance Regulator Chloride-Channel Gating

Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel cause cystic fibrosis. The ΔF508 mutation produces defects in channel gating and cellular processing, whereas the G551D mutation produces primarily a gating defect. To identify correctors of gating, 50,000 diverse small molecules were screened at 2.5 μM (with forskolin, 20 μM) by an iodide uptake assay in epithelial cells coexpressing ΔF508-CFTR and a fluorescent halide indicator (yellow fluorescent protein-H148Q/I152L) after ΔF508-CFTR rescue by 24-h culture at 27°C. Secondary analysis and testing of >1000 structural analogs yielded two novel classes of correctors of defective ΔF508-CFTR gating (“potentiators”) with nanomolar potency that were active in human ΔF508 and G551D cells. The most potent compound of the phenylglycine class, 2-[(2–1H-indol-3-yl-acetyl)-methylamino]-N-(4-isopropylphenyl)-2-phenylacetamide, reversibly activated ΔF508-CFTR in the presence of forskolin with Ka ∼ 70 nM and also activated the CFTR gating mutants G551D and G1349D with Ka values of ∼1100 and 40 nM, respectively. The most potent sulfonamide, 6-(ethylphenylsulfamoyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid cycloheptylamide, had Ka ∼ 20 nM for activation of ΔF508-CFTR. In cell-attached patch-clamp experiments, phenylglycine-01 (PG-01) and sulfonamide-01 (SF-01) increased channel open probability >5-fold by the reduction of interburst closed time. An interesting property of these compounds was their ability to act in synergy with cAMP agonists. Microsome metabolism studies and rat pharmacokinetic analysis suggested significantly more rapid metabolism of PG-01 than SF-03. Phenylglycine and sulfonamide compounds may be useful for monotherapy of cystic fibrosis caused by gating mutants and possibly for a subset of ΔF508 subjects with significant ΔF508-CFTR plasma-membrane expression.
Radio resource management across multiple protocol layers in satellite networks: a tutorial overview

Satellite transmissions have an important role in telephone communications, television broadcasting, computer communications, maritime navigation, and military command and control. Moreover, in many situations they may be the only possible communication set‐up. Trends in telecommunications indicate that four major growth market/service areas are messaging and navigation services (wireless and satellite), mobility services (wireless and satellite), video delivery services (cable and satellite), and interactive multimedia services (fibre/cable, satellite).
Relative strengths of NH..O and CH..O hydrogen bonds between polypeptide chain segments.

Correlated ab initio calculations are used to compare the energetics when the CH and NH groups of the model dipeptide CHONHCH2CONH2 are each allowed to form a H-bond with the proton acceptor O of a peptide group. When the dipeptide is in its C7 conformation, the NH.O H-bond energy is found to be 7.4 kcal/mol, as compared to only 2.8 kcal/mol for the CH.O interaction. On the other hand, the situation reverses, and the CH.O H-bond becomes stronger than NH.O, when the dipeptide adopts a C5 structure. This reversal is important as C5 is nearly equal in stability to C7 for the dipeptide, and is representative of the commonly observed beta-sheet structure in a protein. Immersing the dipeptide-peptide pair in a model solvent weakens both sorts of H-bonds, and in a fairly uniform manner. Consequently, the trends observed in the in vacuo situation retain their validity in either aqueous solution or the protein interior. Likewise, the desolvation penalty, suffered by removing a H-bonded complex from water and placing it in the less polar interior of a protein, is quite similar for the NH.O and CH.O bonds.
PARALLEL COMPILATION OF CMS SOFTWARE

LHC experiments have large amounts of software to build. CMS has studied ways to shorten project build times using parallel and distributed builds as well as improved ways to decide what to rebuild. We have experimented with making idle desktop and server machines easily available as a virtual build cluster using distcc and zeroconf. We have also tested variations of ccache and more traditional make dependency analysis. We report on our test results, with analysis of the factors that most improve or limit build performance.
List-decoding of binary Goppa codes up to the binary Johnson bound

We study the list-decoding problem of alternant codes (which includes obviously that of classical Goppa codes). The major consideration here is to take into account the (small) size of the alphabet. This amounts to comparing the generic Johnson bound to the q-ary Johnson bound. The most favourable case is q = 2, for which the decoding radius is greatly improved. Even though the announced result, which is the list-decoding radius of binary Goppa codes, is new, we acknowledge that it can be made up from separate previous sources, which may be a little bit unknown, and where the binary Goppa codes has apparently not been thought at. Only D. J. Bernstein has treated the case of binary Goppa codes in a preprint. References are given in the introduction. We propose an autonomous and simplified treatment and also a complexity analysis of the studied algorithm, which is quadratic in the blocklength n, when decoding e-away of the relative maximum decoding radius.
The Assessment of Articulation and Phonological Skills in Preschool Cleft Palate Children

There has been a lack of comprehensive analyses of the articulation and phonological skills of preschool cleft palate children. Therefore, a comprehensive analysis, following a model suggested by Ingram (1981), was completed on three preschool children with cleft palates. The analysis was completed on a videotaped conversational play sample. Each sample was transcribed using the International Phonetic Alphabet (IPA), compensatory substitution symbols, and diacritics. The samples were analyzed for a phonetic inventory of the sounds in the initial, medial, and final positions of words; for homonyms; for substitutions, distortions, and omissions; and for phonological processes. Each of the four analyses was summarized on a summary sheet. The results of the study indicated that each of the four analyses provides information that would enhance intervention planning. The results demonstrated that the subjects appeared to benefit more from some of the analyses than others. Each subject scored differently on the whole analysis. This was not predictable from the former testing results available for the subjects. Therefore, it seems essential that a comprehensive speech analysis be provided for preschool children who have cleft palates and are at risk of articulation and phonological delay.
A Framework for End-User Programming of Smart Homes Using Mobile Devices

A crucial challenge to enabling multi-device home networked systems is providing a way for non-expert consumers to combine, configure and control the available functions. Unfortunately, the typical consumers find it difficult to perform tasks using even stand-alone programmable CE devices; programming and controlling smart homes involving a number of connected devices and services represents a significantly bigger challenge. We present our architecture for end-user programming of novel application concepts in smart homes. Our architecture has an end-user layer, a scripting layer, a semantic adaptation layer, a distributed middleware layer and a local system layer. We describe the overall end-user's process for creating applications. We discuss a part of our implementation that automatically discovers and composes devices into arrangements that satisfy the user's goal.
Structure of Mth11/Mth Rpp29, an essential protein subunit of archaeal and eukaryotic RNase P

We have determined the solution structure of Mth11 (Mth Rpp29), an essential subunit of the RNase P enzyme from the archaebacterium Methanothermobacter thermoautotrophicus (Mth). RNase P is a ubiquitous ribonucleoprotein enzyme primarily responsible for cleaving the 5′ leader sequence during maturation of tRNAs in all three domains of life. In eubacteria, this enzyme is made up of two subunits: a large RNA (≈120 kDa) responsible for mediating catalysis, and a small protein cofactor (≈15 kDa) that modulates substrate recognition and is required for efficient in vivo catalysis. In contrast, multiple proteins are associated with eukaryotic and archaeal RNase P, and these proteins exhibit no recognizable homology to the conserved bacterial protein subunit. In reconstitution experiments with recombinantly expressed and purified protein subunits, we found that Mth Rpp29, a homolog of the Rpp29 protein subunit from eukaryotic RNase P, is an essential protein component of the archaeal holoenzyme. Consistent with its role in mediating protein–RNA interactions, we report that Mth Rpp29 is a member of the oligonucleotide/oligosaccharide binding fold family. In addition to a structured β-barrel core, it possesses unstructured N- and C-terminal extensions bearing several highly conserved amino acid residues. To identify possible RNA contacts in the protein–RNA complex, we examined the interaction of the 11-kDa protein with the full 100-kDa Mth RNA subunit by using NMR chemical shift perturbation. Our findings represent a critical step toward a structural model of the RNase P holoenzyme from archaebacteria and higher organisms.
pYAC-RC, a yeast artificial chromosome vector for cloning DNA cut with infrequently cutting restriction endonucleases.

The recent development of yeast artificial chromosome vectors has increased the cloning capacity over bacteriophage and cosmid based systems approximately tenfold, allowing cloning of DNA fragments several hundred kilobases in size (1). This technology bridges a major gap in the ability to clone genetic loci of higher organisms, which often encompass large regions of the genome, as well as current efforts at global mapping of complex genomes. We have developed a yeast artificial chromosome vector containing a polylinker of unique sites for infrequently cutting restriction endonucleases that can be used for generation of whole genome libraries as large DNA fragments or the cloning of specific large fragments of interest.
Locating need-to-translate constant strings for software internationalization

Modern software applications require internationalization to be distributed to different regions of the world. In various situations, many software applications are not internationalized at early stages of development. To internationalize such an existing application, developers need to externalize some hard-coded constant strings to resource files, so that translators can easily translate the application into a local language without modifying its source code. Since not all the constant strings require externalization, locating those need-to-translate constant strings is a necessary task that developers must complete for internationalization. In this paper, we present an approach to automatically locating need-to-translate constant strings. Our approach first collects a list of API methods related to the Graphical User Interface (GUI), and then searches for need-to-translate strings from the invocations of these API methods based on string-taint analysis. We evaluated our approach on four real-world open source applications: RText, Risk, ArtOfIllusion, and Megamek. The results show that our approach effectively locates most of the need-to-translate constant strings in all the four applications.
Enhancing classification performance of multi-class imbalanced data using the OAA-DB algorithm

In data classification, the problem of imbalanced class distribution has attracted many attentions. Most efforts have used to investigate the problem mainly for binary classification. However, research solutions for the imbalanced data on binary-class problems are not directly applicable to multi-class applications. Therefore, it is a challenge to handle the multi-class problem with imbalanced data in order to obtain satisfactory results. This problem can indirectly affect how human visualise the data. In this paper, an algorithm named One-Against-All with Data Balancing (OAA-DB) is developed to enhance the classification performance in the case of the multi-class imbalanced data. This algorithm is developed by combining the multi-binary classification technique called One-Against-All (OAA) and a data balancing technique. In the experiment, the three multi-class imbalanced data sets used were obtained from the University of California Irvine (UCI) machine learning repository. The results show that the OAA-DB algorithm can enhance the classification performance for the multi-class imbalanced data without reducing the overall classification accuracy.
Analysis of Heart Rate Variability Using Time-Varying Frequency Bands Based on Respiratory Frequency

In this paper a methodological approach for the analysis of nonstationary heart rate variability (HRV) signals using time-varying frequency bands based on respiratory frequency is presented. Spectral analysis of HRV is accomplished by means of the Smoothed Pseudo Wigner Ville distribution. Different approaches to the definition of the low frequency (LF) and high frequency (HF) bands are considered which involve respiratory information, derived either from a respiratory signal or from the ECG itself. Results are presented which derive from recordings acquired during stress testing and induced emotion experiments.