Miracle-dz/UniFAR-FTUs huggingface dataset:
Is Technical Analysis Useful for Stock Traders in China? Evidence from the Szse Component A-Share Index

This paper uses daily stock prices and the trading volume of 39 constituent companies in the SZSE Component A-Share Index on the Shenzhen Stock Exchange to examine the usefulness of technical analysis. It finds very weak evidence to support the view that traders and/or technical analysts can learn more about the future pattern of returns by actively using volume in conjunction with returns than those who only watch price movements.
A Model of Rational Competitive Bidding

This paper presents a mathematical model of the bidding process that deals explicitly with the uncertainty of the bidders about the value of the subject of the auction. By dealing with this often ignored factor, it obtains equilibrium strategies and profits as a function of the number of bidders, the relative values they attach to the subject of the auction and their accuracy in estimating it. Models are developed for both highest-bid-wins and lowest-bid-wins auctions.
Combining clientelist and programmatic politics in Tamil Nadu, South India

This article examines the use of material appeals for voter support using evidence taken from the case of the south Indian state of Tamil Nadu. Two types of material appeal co-exist in this case. Clientelist politics, in the form of vote buying, and the distribution of public resources as political patronage, are features of state politics. Parties also use programmatic policies which offer benefits to beneficiaries regardless of partisan affiliation. The provision of such universal benefits has expanded since 2006. Yet the interest in universal provision significantly pre-dates 2006 and can be traced back to elite policy preferences in the early 1980s. The article shows that competition within a clientelist political system need not lead to the intensification of clientelism. Political parties may dilute their clientelist strategy by the addition of some programmatic policies. The wider implication of this study is that future research on material appeals should pay more attention to parties and party systems as causal variables.
Do students behave like adults? Evidence from valuation experiments

The use of convenience samples in experimental economics has long been the standard practice. However, little evidence exists regarding behavioural differences between students and adults in contingent valuation experiments using a payment mechanism other than a referendum vote. Evidence is provided that students do in fact behave in a manner similar to adults using an open-ended willingness to pay payment question.
Characterization of body effect of Au-EGFET for KRAS gene detection

The sensing properties of Au-EGFET with body effect for DNA detection were first investigated in this study. The body effect means different substrate bias in CMOS circuit operation without common ground. With positive VBS of 1V, more shift of ID-VG curve could be a good index of DNA hybridization and concentration. It could be explained be the electric field induced counter ion effect. This measured technique can be used to enhance the sensing signal and improve the limit of detection (LOD).
N-Formyl Peptide Receptors Internalize but Do Not Recycle in the Absence of Arrestins*

Arrestins mediate phosphorylation-dependent desensitization, internalization, and initiation of signaling cascades for the majority of G protein-coupled receptors (GPCRs). Many GPCRs undergo agonist-mediated internalization through arrestin-dependent mechanisms, wherein arrestin serves as an adapter between the receptor and endocytic proteins. To understand the role of arrestins in N-formyl peptide receptor (FPR) trafficking, we stably expressed the FPR in a mouse embryonic fibroblast cell line (MEF) that lacked endogenous arrestin 2 and arrestin 3 (arrestin-deficient). We compared FPR internalization and recycling kinetics in these cells to congenic wild type MEF cell lines. Internalization of the FPR was not altered in the absence of arrestins. Since the FPR remains associated with arrestins following internalization, we investigated whether the rate of FPR recycling was altered in arrestin-deficient cells. While the FPR was able to recycle in the wild type cells, receptor recycling was largely absent in the arrestin double knockout cells. Reconstitution of the arrestin-deficient line with either arrestin 2 or arrestin 3 restored receptor recycling. Confocal fluorescence microscopy studies demonsrated that in arrestin-deficient cells the FPR may become trapped in the perinuclear recycling compartment. These observations indicate that, although the FPR can internalize in the absence of arrestins, recycling of internalized receptors to the cell surface is prevented. Our results suggest a novel role for arrestins in the post-endocytic trafficking of GPCRs.
Maintaining urban greenery in developing countries for tourism and recreation: a benefit-cost analysis

Conserving biodiversity in urban areas of developing countries has become a big challenge. Urban green spaces play a very important role in this direction. Governments in developing countries are recognising the need of increasing forest and tree cover in urban settings. Like other developing countries, India is also rapidly urbanising. Today every fourth Indian is a city-dweller and it is estimated that more than 40% of India's population will reside in urban areas by 2030. An attempt has been made in this paper to demonstrate the worth of maintaining urban green spaces in Chandigarh city of India by way of benefit-cost (B/C) analysis for the well-being of the city residents and tourists as well. The results would be useful for the city administrators, planners, academics, legal community and general public for deciding about urban land uses in more effective manner.
Intimate Partner Violence and Unintended Pregnancy Among Bangladeshi Women

This study examined the relationship between intimate partner violence (IPV) and unintended pregnancy using data from women reporting IPV in the 2007 Bangladesh Demographic Health Survey. The analysis included 4,695 married women, aged 15 to 40 years, who had at least one birth in the last 5 years. Bivariate and multiple logistic regression analyses were performed to assess the relationship between IPV and pregnancy. About one third (30.4%) of women were abused physically and/or sexually and about one third (30.9%) of their births in the last 5 years were unintended. Compared with women who suffered no IPV, women who were abused sexually had a 1.64-fold increased risk of unintended pregnancy, which is higher than those who suffered physical abuse only (odds ratio: 1.35). The prevalence of unintended pregnancy among those who experienced severe physical violence was 1.60 times higher than those who reported no abuse. The findings indicate a significant relationship between IPV and unintended pregnancy among Bangladeshi women.
Cu(I) availability paradoxically antagonizes antioxidant consumption and lipid peroxidation during the initiation phase of copper-induced LDL oxidation.

The incubation of isolated human low-density lipoprotein (LDL) with Cu(II) promoted extensive oxidation of both the lipid and protein moieties of the lipoprotein particle. When the Cu(II) to LDL molar ratio was equal or higher than 50, the removal of Cu(I) formed by the contemporary presence of the Cu(I) chelator bathocuproine disulphonate (BC) markedly accelerated the formation of end-products of lipid peroxidation. Moreover, the initial rate of Cu(II)-induced consumption of either endogenous antioxidants in LDL or free alpha-tocopherol in suspension was increased in the presence of BC, thus indicating that the continuous removal of Cu(I) enhanced both antioxidant consumption and LDL oxidation promoted by copper. Furthermore, the direct addition of Cu(I), together with Cu(II), to a suspension of isolated LDL efficiently delayed the onset of extensive lipid peroxidation and decreased the rate of antioxidant consumption. The latter effect, however, was detectable exclusively on LDL-associated alpha-tocopherol and not on alpha-tocopherol in suspension, thus suggesting that the competition between Cu(I) and Cu(II) was taking place at discrete sites associated with the LDL particle. Finally, the inclusion of Cu(I) in the incubation medium of LDL already undergoing extensive peroxidation did not inhibit but rather markedly stimulated the rate of peroxidation. Although apparently in contrast with the common view that Cu(I) and not Cu(II) is the real trigger species of LDL oxidation in the copper model, the results reported here indicate that the availability of Cu(I) during the initiation phase of LDL oxidation promoted by copper antagonizes both antioxidant consumption and the onset of extensive oxidation.
Tariffs and Declining-Cost Industries

Recently Corden [1] explored some implications of assuming increasing returns and monopoly in an import-competing industry. The models chosen are relevant to considering the effects of tariffs and subsidies in a "young" industrializing economy which plays a relatively minor role in world trade. The main conclusions of the Corden analysis are that (1) tariffs cannot lead to a social optimum; (2) if the country produces the good, it must do so at marginal cost pricing which requires that the industry be subsidized; and (3) the social optimum cannot result from subsidizing imports. This paper is a limited attempt to determine how tariffs and subsidies affect decreasing-cost, import-competing industries where the economy under consideration plays a relatively major role in world trade. The approach is similar to that used by Corden in that it is partial equilibrium analysis. Subject to all the limitations of partial analysis, among the conclusions (where the import-competing industry is of a decreasingcost nature) are (1) an optimum tariff can exist such that through subsidization there will be domestic production and imports, not all of one or the other; (2) the imposition of tariffs may actually cause prices in the import-competing industry to fall; (3) in other cases it is possible to achieve a social optimum by producing all of the good domestically and subsidizing domestic production; and (4) a social optimum can be achieved by subsidizing imports. In the first case considered, the free-trade price is such that in the absence of barriers to trade all of the good consumed domestically is imported. Thus, the good is not produced by a monopoly in the importing country. It is shown in Figure 1 that a tariff can lead to a net welfare gain and that an optimum tariff exists. The demand schedule in the importing country is AR; the average and marginal cost curves are ACd and MCd.2 It is assumed that the cost curves reflect both private and social costs. To be consistent with Corden's analysis, the possibility
Learning Context-Sensitive Domain Ontologies from Folksonomies: A Cognitively Motivated Method

Ontology is the backbone of the Semantic Web, helping users search for relevant resources from the Web of linked data. The existing context-free mapping approach between tags and concepts fails to address the problems of social synonymy and social polysemy when ontologies are induced from folksonomies. The novel contributions of this paper are threefold. First, grounded in the cognitively motivated category utility measure, a novel basic-level concept mining algorithm is developed to construct semantically rich concept vectors to alleviate the problem of social synonymy. Second, contextual aspects of ontology learning are exploited via probabilistic topic modeling to address the problem of social polysemy. Third, a novel context-sensitive domain ontology learning algorithm that combines link- and content-based semantic analysis is developed to identify both taxonomic and associative relations among concepts. To the best of our knowledge, this is the first successful research that exploits a cognitively mo.
Optimal algorithms and lower partial moment: ex post results

Portofolio management in the finance literature has typically used optimization algorithms to determine security allocations within a portfolio in order to obtain the best trade-off between risk and return. These algorithms, despite some improvements, are restrictive in terms of an investor's risk aversion (utility function). Since individual investors have different levels of risk aversion, this paper proposes two portfolio-optimization algorithms that can be tailored to the specific level of risk aversion of the individual investor and performs ex postevaluation tests of the algorithm performance.
Generating anatomically accurate finite element meshes for electrical impedance tomography of the human head

For electrical impedance tomography (EIT) of brain, the use of anatomically accurate and patient-specific finite element (FE) mesh has been shown to confer significant improvements in the quality of image reconstruction. But, given the lack of a rapid method to achieve the accurate anatomic geometry of the head, the generation of patient-specifc mesh is time-comsuming. In this paper, a modified fuzzy c-means algorithm based on non-local means method is performed to implement the segmentation of different layers in the head based on head CT images. This algorithm showed a better effect, especially an accurate recognition of the ventricles and a suitable performance dealing with noise. And the FE mesh established according to the segmentation results is validated in computational simulation. So a rapid practicable method can be provided for the generation of patient-specific FE mesh of the human head that is suitable for brain EIT.
EDH: endothelium‐dependent hyperpolarization and microvascular signalling

Endothelium‐dependent hyperpolarizing factor (EDHF) is a powerful vasodilator influence in small resistance arteries and thus an important modulator of blood pressure and flow. As the name suggests, EDHF was thought to describe a diffusible factor stimulating smooth muscle hyperpolarization (and thus vasodilatation). However, this idea has evolved with the recognition that a factor can operate alongside the spread of hyperpolarizing current from the endothelium to the vascular smooth muscle (VSM). As such, the pathway is now termed endothelium‐dependent hyperpolarization (EDH). EDH is activated by an increase in endothelial [Ca2+]i, which stimulates two Ca2+‐sensitive K channels, SKCa and IKCa. This was discovered because apamin and charybdotoxin applied in combination blocked EDHF responses, but iberiotoxin – a blocker of BKCa – was not able to substitute for charybdotoxin. SKCa and IKCa channels are arranged in endothelial microdomains, particularly within projections towards the adjacent smooth muscle, which are rich in IKCa channels and close to interendothelial gap junctions where SKCa channels, are prevalent. KCa activation hyperpolarizes endothelial cells, and K+ efflux through them can act as a diffusible ‘EDHF’ by stimulating VSM Na+,K+‐ATPase and inwardly rectifying K channels (KIR). In parallel, hyperpolarizing current spreads from the endothelium to the smooth muscle through myoendothelial gap junctions located on endothelial projections. The resulting radial EDH is complemented by the spread of ‘conducted’ hyperpolarization along the endothelium of arteries and arterioles to affect conducted vasodilatation (CVD). Retrograde CVD effectively integrates blood flow within the microcirculation, but how the underlying hyperpolarization is sustained is unclear.
Detecting market transitions and energy futures risk management using principal components

Abstract An empirical approach to analysing the forward curve dynamics of energy futures is presented. For non-seasonal commodities—such as crude oil—the forward curve is well described by the first three principal components: the level, slope and curvature. A principal component indicator is described that detects transitions between the two fundamental market states remarkably well. For seasonal commodities—such as electricity and natural gas—it is shown how to extract the seasonal component from the forward curve. The principal component indicator can then be applied to the de-seasoned forward curve to detect significant price deviations that may support profitable trading strategies. A principal component approach to forward curve modelling is applied to computing portfolio value-at-risk. This approach is combined with a new two-step resampling procedure to improve value-at-risk estimates.
From sponsor to partner: NGO–business alliances that support nature conservation in the Netherlands

Recent developments in the Netherlands have encouraged a shift in the focus of non-governmental organisations (NGOs) from maintaining links with the public sector towards forging new links with private actors. Although businesses increasingly shape society, their potential contribution to nature conservation has not been fully explored. This article outlines the incentives for collaboration between businesses and nature organisations at regional and national levels. This study is based on interviews held with business representatives and fund-raising officers. The results show that the limited awareness of one's own identity is a hindrance to the development of alliances from a sponsor into a partner relation. Nature organisations are unable to recognise their appealing aspects for businesses, while businesses are not always outspoken about their desired societal role. Further, businesses at regional and national levels differ in their motivation for collaboration with NGOs. To improve the collaboration, each party has to identify which resources they can offer in a relationship, and what they would like to gain in return.
Proteomic Analysis of Seed Filling in Brassica napus. Developmental Characterization of Metabolic Isozymes Using High-Resolution Two-Dimensional Gel Electrophoresis1[W]

Brassica napus (cultivar Reston) seed proteins were analyzed at 2, 3, 4, 5, and 6 weeks after flowering in biological quadruplicate using two-dimensional gel electrophoresis. Developmental expression profiles for 794 protein spot groups were established and hierarchical cluster analysis revealed 12 different expression trends. Tryptic peptides from each spot group were analyzed in duplicate using matrix-assisted laser desorption ionization time-of-flight mass spectrometry and liquid chromatography-tandem mass spectrometry. The identity of 517 spot groups was determined, representing 289 nonredundant proteins. These proteins were classified into 14 functional categories based upon the Arabidopsis (Arabidopsis thaliana) genome classification scheme. Energy and metabolism related proteins were highly represented in developing seed, accounting for 24.3% and 16.8% of the total proteins, respectively. Analysis of subclasses within the metabolism group revealed coordinated expression during seed filling. The influence of prominently expressed seed storage proteins on relative quantification data is discussed and an in silico subtraction method is presented. The preponderance of energy and metabolic proteins detected in this study provides an in-depth proteomic view on carbon assimilation in B. napus seed. These data suggest that sugar mobilization from glucose to coenzyme A and its acyl derivative is a collaboration between the cytosol and plastids and that temporal control of enzymes and pathways extends beyond transcription. This study provides a systematic analysis of metabolic processes operating in developing B. napus seed from the perspective of protein expression. Data generated from this study have been deposited into a web database (http://oilseedproteomics.missouri.edu) that is accessible to the public domain.
Fyn kinase is involved in oligodendroglial cell differentiation induced by apotransferrin

Mechanisms that regulate oligodendroglial cell (OLGc) differentiation are the focus of intensive research in the field of cellular and molecular neurobiology. We have previously shown that the addition of apotransferrin (aTf) to primary OLGc cultures accelerates their differentiation and induces an increase in the expression of different components of the myelin cytoskeleton (CSK) such as actin, tubulin, and some of the microtubule‐associated proteins, particularly the stable tubulin only peptide (STOP). Fyn protein‐tyrosine kinase (Fyn kinase), a member of the Src family, participates in signalling pathways that regulate OLGs/myelin cytoskeletal reorganization. It is essential for myelin development in the central nervous system (CNS), and its absence results in hypomyelination. In the present study, we used both primary cell and N19 cell line cultures to investigate further the mechanisms of action involved in the accelerated differentiation of OLGcs induced by aTf. In particular, we were interested in studying the participation of Fyn kinase in the different pathways involved in the reorganization of the OLGc/myelin cytoskeleton. In agreement with results already published, we found that in OLGcs, Fyn kinase is associated with Tau and tubulin. Using a dominant‐negative of Tau in which the Fyn‐Tau‐microtubules (MTs) interaction is blocked, we found that aTf was unable to induce OLGc morphological differentiation. It was also observed that aTf decreases the activated RhoA content in coincidence with a redistribution of actin immunoreactivity. These results give support to our hypothesis that Fyn kinase plays a key role in the differentiation process of OLGcs promoted by aTf. © 2008 Wiley‐Liss, Inc.
Physical and biological features of polyoma virus mutants able to infect embryonal carcinoma cell lines

Three new polyoma mutants were selected for their ability to grow on the embryonal carcinoma cell line F9. These mutants share in common an insertion of two nucleotides, a thymine and an adenine, in the noncoding region located on the late side of the origin of replication. We have found that these insertions exist in all of the other polyoma virus mutants able to grow on F9 cells (Fujimura et al., Cell 23:809-814, 1981; Katinka et al., Nature (London) 290:720-722, 1981; K. Sekikawa and A. J. Levine, Proc. Natl. Acad. Sci. U.S.A. 78:1100-1104, 1981). The region containing these insertions could be folded into a stable secondary structure which included a guanine plus cytosine (G + C)-rich stem. The adenine and thymine were inserted in such a way that they maintained the palindrome in the G + C-rich stem and were complementary in the putative secondary structure that we present here. Another class of polyoma virus mutants selected on a multipotential carcinoma cell line (PCC4-Aza) were characterized by a more complex rearrangement (deletion and duplication) which occurred in the same region. This arrangement preserved the G + C-rich palindrome and also yielded a sequence which still allowed the folding of another type of stable secondary structure. The significance of these findings is discussed.
Binary Regression with Misclassified Response and Covariate Subject to Measurement Error: a Bayesian Approach

We consider a Bayesian analysis for modeling a binary response that is subject to misclassification. Additionally, an explanatory variable is assumed to be unobservable, but measurements are available on its surrogate. A binary regression model is developed to incorporate the measurement error in the covariate as well as the misclassification in the response. Unlike existing methods, no model parameters need be assumed known. Markov chain Monte Carlo methods are utilized to perform the necessary computations. The methods developed are illustrated using atomic bomb survival data. A simulation experiment explores advantages of the approach. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)