Miracle-dz/UniFAR-FTUs huggingface dataset:
Participant Satisfaction with Wellness Recovery Action Plan (WRAP)

Outpatient programs are often promoted as vehicles for mental health recovery. Yet, few programs include patients’ perspectives about their satisfaction with these programs. This descriptive, cross-sectional survey investigated patients’ satisfaction with Wellness Recovery Action Plan (WRAP). Participants completed the Mental Health Statistics Improvement Program instrument (n = 26) and qualitative interviews (n = 18). Data were analyzed using multivariate statistics (α = .05) and content analysis. Three composite variables explained 48% of the variance (p = .00) in patient satisfaction. Four themes emerged: Retrospective Desire for Early WRAP Introduction, Pay It Forward, Unconditional Relational Support, and It Takes Time. Future research is warranted to promote WRAP's use in broader settings.
Molecular Chaperones: The Plant Connection

Molecular chaperones are a family of unrelated proteins found in all types of cell. They mediate the correct assembly of other polypeptides, but are not components of the mature assembled structures. Chaperones function by binding specifically to interactive protein surfaces that are exposed transiently during many cellular processes and so prevent them from undergoing incorrect interactions that might produce nonfunctional structures. The concept of molecular chaperones originated largely from studies of the chloroplast enzyme rubisco, which fixes carbon dioxide in plant photosynthesis; the function of chaperones forces a rethinking of the principle of protein self-assembly.
On steady‐state tropical cyclones

We examine the physical constraints that must be satisfied to allow for a steady‐state tropical cyclone in an isolated environment, paying particular attention to the need to replenish absolute angular momentum at exactly the rate at which it is consumed and to the vanishing of the spin‐up function above the frictional boundary layer. We conclude that it is unlikely that these conditions will be met simultaneously and question whether globally steady‐state tropical cyclone solutions have merit. The implications for previous studies are discussed.
Adaptive robust motion control of the surface mounting equipment with dynamic friction compensation

The surface mounting equipment (SME) is a critical and complex industrial system which require high-accuracy and high-speed linear motion. In SME applications, the point-to-point motion is the main motion trajectory and often subjected to parametric uncertainties and uncertain nonlinearities. To achieve high performance of the SME, the adaptive robust motion control algorithm with dynamic friction compensation using LuGre model is proposed in this paper. For the parametric uncertainties, this algorithm uses a discontinuous projection-type method to estimate the system parameters. Under the assumption that the disturbance is bounded, the algorithm can be compensate the uncertain nonlinearities. Dynamic friction compensation using LuGre model is introduced instead of traditional static friction compensation. And the nonlinear state observer is designed to estimate unmeasurable friction state. Along with PID and deterministic robust control scheme, the proposed controller is implemented on an SME system at high speed and low speed point-to-point movement. Comparative experimental results reveal the improved tracking accuracy and validate the effectiveness of the proposed approach in SME applications.
Calculation of coupled-cavity TWT performance

A method of calculation of coupled-cavity TWT performance which is programmable for fast and economical calculation on a time-sharing computer is presented. The tube is modeled as a sequence of interaction gaps and tunnels, with cavities associated with each gap. The fields are expanded in terms of a sequence of stationary waves anchored on each gap, instead of a set of traveling waves. Space-charge forces are calculated by a fast potential-gradient method instead of from a Green's function. These methods allow flexibility in the model as well as speed. The method is applied to three simple examples, to show the behavior of components of a TWT, and then to two actual designs.
Peritoneal Carcinomatosis in Patients With Ovarian Cancer: Enhanced CT Versus 18F-FDG PET/CT

Purpose The study aimed to evaluate the efficacy of PET/CT in detecting peritoneal carcinomatosis in patients with ovarian cancer and to compare the diagnostic accuracy of FDG PET/CT with that of enhanced abdominal CT. Methods The medical records of 46 consecutive patients with ovarian cancer were reviewed, and the presence of peritoneal tumor on 18F-FDG PET/CT and enhanced abdominal CT scans was also assessed. Imaging results were compared with the pathologic findings obtained by surgery. Results Pathologic results were positive for peritoneal carcinomatosis in 26 patients and negative in 20 patients. PET/CT correctly detected 25 of 26 patients with peritoneal carcinomatosis and enhanced abdominal CT correctly detected 23 of 26 patients. Sensitivity and specificity for the diagnosis of peritoneal carcinomatosis were 96.2% and 90%, respectively, for PET/CT and 88.5% and 65%, respectively, for enhanced abdominal CT. The accuracy of PET/CT was statistically higher than that of enhanced abdominal CT (93.5% vs 78.3%, P = 0.039). Four distinctly abnormal PET/CT findings of single nodular, multiple nodular, diffuse, and mixed FDG uptakes were identified and corresponded to pathologic findings. Conclusions 18F-FDG PET/CT imaging is efficient in the diagnosis of peritoneal carcinomatosis and its performance is superior to that of enhanced abdominal CT.
Designing cavity-enclosed microstrip antenna for gain enhancement

The antenna has been designed to observe and analyze the effect of the addition of perfect electric conductive (PEC) cavity-enclosed to a rectangular microstrip antenna. The calculated parameters have been optimized using Computer Simulation Technology (CST) software. The design prototype has been fabricated and the output was measured using Vector Network Analyzer (VNA). The simulated and measured results are then compared. It is observed that the gain is improved when PEC cavity is added to the microstrip antenna.
Antithrombotic drug therapy for IgA nephropathy: a meta analysis of randomized controlled trials.

BACKGROUND Antithrombotic agents, including antiplatelet agents, anticoagulants and thrombolysis agents, have been widely used in the management of immunoglobulin A (IgA) nephropathy in Chinese and Japanese populations. To systematically evaluate the effects of antithrombotic agents for IgA nephropathy. METHODS Data sources consisted of MEDLINE, EMBASE, the Cochrane Library, Chinese Biomedical Literature Database (CBM), Chinese Science and Technology Periodicals Databases (CNKI) and Japana Centra Revuo Medicina (http://www.jamas.gr.jp) up to April 5, 2011. The quality of the studies was evaluated from the intention to treat analysis and allocation concealment, as well as by the Jadad method. Meta-analyses were performed on the outcomes of proteinuria and renal function. RESULTS Six articles met the predetermined inclusion criteria. Antithrombotic agents showed statistically significant effects on proteinuria (p<0.0001) but not on the protection of renal function (p=0.07). The pooled risk ratio for proteinuria was 0.53, [95% confidence intervals (CI): 0.41-0.68; I(2)=0%] and for renal function it was 0.42 (95% CI 0.17-1.06; I(2)=72%). Subgroup analysis showed that dipyridamole was beneficial for proteinuria (p=0.0003) but had no significant effects on protecting renal function. Urokinase had statistically significant effects both on the reduction of proteinuria (p=0.0005) and protecting renal function (p<0.00001) when compared with the control group. CONCLUSION Antithrombotic agents had statistically significant effects on the reduction of proteinuria but not on the protection of renal function in patients with IgAN. Urokinase had statistically significant effects both on the reduction of proteinuria and on protecting renal function. Urokinase was shown to be a promising medication and should be investigated further.
Expression Cloning and Biochemical Characterization of a Rhizobium leguminosarum Lipid A 1-Phosphatase*

Lipid A of Rhizobium leguminosarum, a nitrogen-fixing plant endosymbiont, displays several significant structural differences when compared with Escherichia coli. An especially striking feature of R. leguminosarum lipid A is that it lacks both the 1- and 4′-phosphate groups. Distinct lipid A phosphatases that attack either the 1 or the 4′ positions have previously been identified in extracts of R. leguminosarum and Rhizobium etli but not Sinorhizobium meliloti or E. coli. Here we describe the identification of a hybrid cosmid (pMJK-1) containing a 25-kb R. leguminosarum 3841 DNA insert that directs the overexpression of the lipid A 1-phosphatase. Transfer of pMJK-1 into S. meliloti 1021 results in heterologous expression of 1-phosphatase activity, which is normally absent in extracts of strain 1021, and confers resistance to polymyxin. Sequencing of a 7-kb DNA fragment derived from the insert of pMJK-1 revealed the presence of a lipid phosphatase ortholog (designated LpxE). Expression of lpxE in E. coli behind the T7lac promoter results in the appearance of robust 1-phosphatase activity, which is normally absent in E. coli membranes. Matrix-assisted laser-desorption/time of flight and radiochemical analysis of the product generated in vitro from the model substrate lipid IVA confirms the selective removal of the 1-phosphate group. These findings show that lpxE is the structural gene for the 1-phosphatase. The availability of lpxE may facilitate the re-engineering of lipid A structures in diverse Gram-negative bacteria and allow assessment of the role of the 1-phosphatase in R. leguminosarum symbiosis with plants. Possible orthologs of LpxE are present in some intracellular human pathogens, including Francisella tularensis, Brucella melitensis, and Legionella pneumophila.
Speech sample salience analysis for speech cycle detection

The presentation proposes a method for the measurement of cycle lengths in voiced speech. The background is the study of acoustic cues of slow (vocal tremor) and fast (vocal jitter) perturbations of the vocal frequency. Here, these acoustic cues are obtained by means of a temporal method that detects speech cycles via the so-called salience of the speech signal samples. The method does not request that the signal is locally periodic and the average period length is known a priori. Several implementations are considered and discussed. Salience analysis is compared with the auto-correlation method for cycle detection implemented in Praat.
Relationship between body size of adult Anopheles gambiae s.l. and infection with the malaria parasite Plasmodium falciparum

SUMMARY The influence of adult female body size of Anopheles gambiae s.l. on development of midgut and salivary gland infections by the parasite Plasmodium falciparum was investigated in a field study carried out in Tanzania. The proportion of mosquitoes infected during a blood meal was independent of size. However, the number of oocysts harboured by infected mosquitoes increased with size of the mosquito. The proportion of mosquitoes with sporozoites, and thus potentially infective to humans, was highest in intermediate-sized mosquitoes, whereas the largest and smallest mosquitoes were less likely to have sporozoites. This pattern is interpreted as a combination of high survival rate of large, uninfected mosquitoes and of low survival rate of mosquitoes infected with many oocysts.
Collagenolytic activity in malignant melanoma: physiocochemical studies.

Human malignant melanoma was shown to contain collagenolytic enzymes. With the use of radioactively labeled reconstituted collagen substrate, the enzyme activity of the tumor homogenate supernatant released radioactivity up to 24 times greater than normal skin and 100% more than benign melanotic tumors such as a junctional nevus and a cellular blue nevus. The known specific collagenase inhibitors significantly inhibited the enzyme activity, whereas soybean trypsin inhibitor did not. Kinetic studies demonstrated a linear increase of collagenolytic activity with respect to enzyme concentration and time of incubation. The optimum pH for enzyme action was 8.5. Disc electrophoresis of the reaction mixture showed collagen degradation products such as β A , α A , and α B . Viscometric studies demonstrated that melanoma crude enzyme decreased the specific viscosity of salt-soluble guinea pig tropocollagen. The denaturation temperature of tropocollagen was decreased as a result of incubation with the melanoma homogenate. These results clearly indicate that the tumor contained active collagenase in vivo .
Slideshow presentation control through hand pattern recognition using web camera

Slideshow presentations are an efficient and effective way to present lectures of all topics. Unfortunately, the lecturer has to stay in close proximity to the device they are using in order to manipulate the presentation. The lecturer may choose to obtain a clicker, but it is then bound by dependence on batteries, and has an additional cost. In order to solve this problem, the researchers propose a system which allows the user to manipulate slideshow presentations with the use of hand patterns captured through the device's built-in camera. The hand in use is to wear a green glove to isolate the region of interest by color segmentation. The hand detection and recognition system are executed in MATLAB and its features are extracted using Principal Component Analysis (PCA). The classification of the pattern is done through the use of the K-Nearest Neighbor Algorithm (KNN). Once the hand pattern is identified, it will be converted to a specific keyboard shortcut in the slideshow presentation software and the command will be executed.
A fuzzy logic based controller for an indirect vector controlled three-phase induction motor

This paper presents the theory, design and simulation of a fuzzy logic based controller used for an indirect vector controlled three-phase induction motor. The analysis, design and simulation of the fuzzy logic controller for IVCIM drive system are carried out based on the fuzzy set theory. The FLC algorithm has been simulated on Simulink Toolbox in Matlab. The performance of the proposed FLC has been investigated and compared to the results obtained from the conventional PI controller based drive at different operating conditions such as sudden change in load. The simulation results demonstrate that the performance of the FLC is better than that for the conventional PI controller.
Title Characterization of human and mouse peroxiredoxin IV: Evidence for inhibition by Prx-IV of epidermal growth factor- and p53-induced reactive oxygen species

The aim of this study was to identify and characterize human and mouse Prx-IV. We identified mouse peroxiredoxin IV (Prx-IV) by virtue of sequence homology to its human ortholog previously called AOE372. Mouse PrxIV conserves an amino-terminal presequence coding for signal peptide. The amino acid sequences of mature mouse and human Prx-IV share 97.5% identity. Phylogenetic analysis demonstrates that Prx-IV is more closely related to Prx-I/-II/-III than to Prx-V/-VI. Previously, we mapped the mouse Prx-IV gene to chromosome X by analyzing two sets of multiloci genetic crosses. Here we performed further comparative analysis of mouse and human Prx-IV genomic loci. Consistent with the mouse results, human Prx-IV gene localized to chromosome Xp22.135–136, in close proximity to SAT and DXS7178. A bacterial artificial chromosome (BAC) clone containing the complete human Prx-IV locus was identified. The size of 7 exons and the sequences of the splice junctions were confirmed by PCR analysis. We conclude that mouse Prx-IV is abundantly expressed in many tissues. However, we could not detect Prx-IV in the conditioned media of NIH-3T3 and Jurkat cells. Mouse Prx-IV was specifically found in the nucleusexcluded region of cultured mouse cells. Intracellularly, overexpression of mouse Prx-IV prevented the production of reactive oxygen species induced by epidermal growth factor or p53. Taken together, mouse Prx-IV is likely a cytoplasmic or organellar peroxiredoxin involved in intracellular redox signaling. Antiox. Redox Signal. 2, 507–518.
Effects of Firm responses to anti-Firm Episodes on Social Media

Due to the increasing prevalence of IT-mediated communication between firms and their stakeholders in digital ecosystems, it is particularly important to add to theory in the Information Systems area on firm reactions during online anti-firm episodes (AFEs). Specifically, the current study addresses both (a) whether firm interventions during a crisis have an effect on the AFE, both in terms of the growth of the episode and the sentiment expressed by the social media users, and (b) how different firm intervention strategies affect the AFE. Drawing from the research area of conflict management from psychological science, we apply the Situational Crisis Communication Theory to develop hypotheses on four relational styles which firms may apply in their IT-mediated crisis management activities. Analyzing 325 AFEs, we show that firm responses can be a double-edged sword. The firm runs the risk of attracting extra attention to the crisis, but is at least able to influence the sentiment of the discussion in its favor. A wholly new finding is that when a firm’s reaction avoids the specific criticism of an ongoing crisis, instead aiming to bolster the firm’s reputation, this is most beneficial to the firm, both for reducing AFE growth and increasing pro-firm sentiment.
Implementation of Radiating Aperture Field Distribution Using Tensorial Metasurfaces

This paper deals with the design of tensorial modulated metasurfaces able to implement a general radiating aperture field distribution. A new aperture synthesis approach is introduced, based on local holography and variable impedance modulation. In particular, it is shown that tensorial metasurfaces can be used to generate general radiating distribution (phase and amplitude). In addition, a step-by-step algorithm is presented. In order to validate the method, several solutions are presented at 20 GHz which implement aperture distributions able to radiate different beams with general polarization.
Fabrication of polycaprolactone collagen hydrogel constructs seeded with mesenchymal stem cells for bone regeneration

The osteogenic differentiation of bone marrow-derived human mesenchymal stem cells (MSCs) in a collagen I hydrogel was investigated. Collagen hydrogels with 7.5 × 105 MSCs ml−1 were fabricated and cultured for 6 weeks in a defined, osteogenic differentiation medium. Histochemistry revealed morphologically distinct, chondrocyte-like cells, surrounded by a sulfated proteoglycan-rich extracellular matrix in the group treated with bone morphogenetic protein 2 (BMP-2), while cells cultured with dexamethasone, ascorbate-2-phosphate, and β-glycerophosphate displayed a spindle-shaped morphology and deposited a mineralized matrix. Real-time polymerase chain reaction (RT-PCR) analyses revealed a specific chondrogenic differentiation with the expression of cartilage-specific markers in the BMP-2-treated group and a distinct expression pattern of the osteogenic markers alkaline phosphatase (ALP), type I collagen, osteocalcin (OC), and cbfa-1 in the group treated with an osteogenic standard medium. The collagen gels were used to engineer a cell laden medical grade ε-polycaprolactone (PCL)-hydrogel construct for segmental bone repair showing good bonding at the scaffold hydrogel interface and even cell distribution. The results show that MSCs cultured in a collagen I hydrogel are able to undergo a distinct osteogenic differentiation pathway when stimulated with specific differentiation factors and suggest that collagen I hydrogels are a suitable means to facilitate cell seeding of scaffolds for bone tissue engineering applications.
A Broadband Patch Antenna Array With Planar Differential L-Shaped Feeding Structures

This study involved developing a differential patch antenna array featuring a wide bandwidth and improved radiation patterns. The proposed patch array was fed by a planar, aperture-coupled, L-shaped feeding structure to achieve wideband operation. The differential feeding structure improved the current distribution of resonant modes, substantially improving the symmetry of radiation patterns. The array without differential excitation revealed an apparent deflected peak located at an observation angle of 10° at 13.7 GHz. However, using the proposed differential-fed structure, the location of this peak returned to 0°. The measured results indicated a wide impedance bandwidth of 21.5% and a stable gain varying from 10.3 to 11.52 dBi over the frequency range of 11.6-15 GHz.
Protection of microprocessor-based cores for FPL devices

Microprocessor cores are widely used in the development of complex digital systems. In this paper, a new scheme for the IP protection of microprocessor cores is presented. The proposed framework can perform this task in two ways: the hosting of a digital signature using watermarking techniques that allows claiming authorship rights; and the introduction of additional hardware limiting the functionality of the core if it is not activated. This last feature enables the distribution of cores in “demo” mode. The protection method, named μIPP@HDL provides a robust protection system, while maintaining low overhead and a reasonable area increase, as experimental results show.
5,10-methylenetetrahydrofolate reductase common mutations, folate status and plasma homocysteine in healthy French adults of the Supplementation en Vitamines et Mineraux Antioxydants (SU.VI.MAX) cohort.

The 677cytosine mutation identified in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene has been frequently associated with an elevated plasma homocysteine concentration. The aim of the present study was to determine the impact of this MTHFR common mutation on plasma and erythrocyte folate (RCF) and plasma total homocysteine (tHcy) concentrations in healthy French adults. A cohort of 291 subjects living in the Paris area and participating in the Supplementation en Vitamines et Mineraux Antioxydants (SU.VI.MAX) study were analysed to assess the impact of MTHFR polymorphism 677C-->T on folate status and plasma tHcy concentration. The frequency of the mutant homozygote for 677C-->T polymorphism (677TT genotype) in the present cohort was 16.8%. There were significant differences in plasma tHcy between 677CC, 677CT and 677TT genotype groups. The RCF concentrations were significantly different between each genotype, the lowest levels being associated with the 677TT genotype. When segregated by gender, no differences in tHcy between homozygous 677TT, heterozygous 677CT and wild-type 677CC genotype groups in women were observed. The fasting tHcy in women was unrelated to the 677C-->T mutation. However, tHcy was significantly increased in men with the homozygous 677TT genotype. We also analysed the possible implication of a second new MTHFR polymorphism (1298A-->C) in subjects with mild hyperhomocysteinaemia (4th quartile of homocysteinaemia; tHcy >11.1 micromol/l). The polymorphism 1298A-->C did not have a notable effect on tHcy or on the RCF levels. Our observations confirm a relatively high frequency of the 677TT genotype in the French population. Women with this genotype did not show the same increase in tHcy observed in men. In the present study dietary folate intake was not measured. Thus, the interaction of dietary folate with the MTHFR genotype in the French population needs further study.