Miracle-dz/UniFAR-FTUs huggingface dataset:
Optimization of wavelet filters for parity relation-based fault detection

This paper revisits a wavelet approach for parity relation-based fault detection and proposes an improvement through the adaptation of the wavelet filters employed in the decomposition of the residue signal. In the parity space approach under consideration, the parity vector is obtained by minimizing a cost that expresses a compromise between sensitivity to faults and robustness against external disturbances. The proposed improvement consists of optimizing the wavelet filter parameters in order to further reduce the resulting cost value. An example involving the model of a two-mass-spring system is presented for illustration. The results show that the proposed filter optimization procedure results in a larger increase of the residue following the onset of a fault, without introducing additional time delays in the detection process.
Effect of Biofertilizer on Growth and Yield Characteristics of Zea mays L. in Different Ecological Zones in Kenya

In order to reduce the dependence on chemical fertilizers, alternative methods should be developed which will provide nutrients to plants. The increased cost of inorganic fertilizers, including their inability to condition the soil and their polluting effect on the environment, has directed attention towards other sources of soil fertilization to enhance maize production. Hence, this study was carried out to determine the effect of Effective Micro-organisms (biofertilizer) comprising Pseudomonas spp, Saccharomyces spp, Bacillus subtilis and Lactobacillus spp. on the growth and yield components of Zea mays L. The trial plots measured 4 m×3 m and the experimental design was randomized complete block design (RCBD) with 4 treatments namely; Biogrovit (biofertilizer) alone; conventional fertilizer alone, Biogrovit plus conventional fertilizer combined and the control. It was replicated three times. Biogrovit was soil drenched in plants at an interval of 14 days in crops established at two sites in Kirinyaga and Machakos County. Significant differences were observed in the leaf area where application of the biofertilizer had the largest (995 cm2) while the least was under the control (529 cm2). The grain yield was notably influenced by application of treatments at both sites, where the highest was recorded under the biofertilizer in Kirinyaga (8.6 t/ha) and Machakos (7.77 t/ha) which was not significantly different from that of the conventional fertilizers in Kirinyaga and Machakos at 7.55 t/ha and 6.87 t/ha respectively. The control had the lowest grain yield in both sites. The 1000-grain mass, ear length, cob weight, number of cobs per plant and the number of kernels per cob directly influenced the actual grain yield as they were higher for both biofertilizer and chemical treatments. The application of Biofertilizer and conventional fertilizer combined at full rates were antagonistic as most of the parameters tested had lower counts than when independently applied. Therefore, the findings of this study suggest that biofertilizers enhance the growth of maize and as such its use should be encouraged because it is eco-friendly.
Sialic acid moieties on surface glycoproteins protect endothelial cells from proteolytic damage

The importance of the glycocalyx in controlling responses to proteinases was studied by enzymic removal of sialic acids from the luminal surface of arterial endothelium. In the perfused rat aorta collagenase induced cell detachment in greater numbers from the desialylated than from the untreated endothelium. Neuraminidase treatment increased by three‐fold prostacyclin synthesis by the vessel wall in respons to thrombin. The supernatant from activated human neutrophils, containing elastolytic activity, when perfused together with neuraminidase enhanced and prolonged sialic acid release induced by neuraminidase alone. Thus the effects of different proteinases on various endothelial cell functions are potentiated by removal of surface sialic acid residues.
Cloning and Sequencing of an Epoxide Hydrolase Gene from Rhodosporidium paludigenum

Epoxide hydrolase (EH) activity was recently described in yeasts and highly selective hydrolysis of epoxides was observed during whole cell biotransformations. To expand the available molecular data regarding yeast EHs, the EH encoding gene from Rhodosporidium paludigenum (CBS 6565) was isolated, cloned and sequenced. The genomic EH sequence revealed a 1600 bp sequence interrupted by six introns. cDNA sequence analysis revealed an open reading frame of 1236 bp with a deduced polypeptide length of 411 amino acids. The deduced amino acid sequence revealed a relative high degree of sequence homology compared to the amino acid sequence of the EH from Rhodotorula glutinis.
Metodología observacional y psicología del deporte

En este trabajo se realiza un analisis en perspectiva de la trayectoria de la Metodologia Observacional en el devenir de la Psicologia del Deporte. La crisis de la Psicologia Social implica un cambio metodologico hacia la observacion, esta situacion es recogida por los trabajos pioneros de Martens y supone su consolidacion. En la ultima decada se ha producido un avance considerable, materializado y consolidado por un desarrollo emergente de diferentes aspectos procedimentales de la Metodologia Observacional (disenos, instrumentos de observacion, programas informaticos de registro, etc.) en Psicologia del Deporte, y en las mas diversas modalidades (futbol, balonmano, baloncesto, hockey, natacion, tenis, judo, actividad fisica, atletismo, etc.). Nos hallamos en la actualidad en un momento que consideramos crucial para que sigan fructificando los nuevos avances metodologicos, desde un planteamiento flexible y abierto, en la multiplicidad de perspectivas perceptibles que se plantean en la Psicologia del Deporte.
Preservation of corynebacteriophages by freeze-drying

SUMMARY A method of freeze-drying is described by which the activity of a series of corynebacteriophages was maintained over a test period of 30 months, whereas some of these strains became inactive if stored as liquid filtered lysates at 4° C, or frozen and held at − 25° C.
A 1.2 V 114 mW Dual-Band Direct-Conversion DVB-H Tuner in 0.13 $\mu$ m CMOS

A fully integrated direct-conversion tuner is implemented in 0.13 mum CMOS technology. A broadband noise-canceling balun LNA with the proposed dual cross-coupling technique helps achieve an overall receiver noise figure from 3.7 to 4.3 dB while consuming only 3.6 mW. The proposed current-mode switching scheme improves the achievable SNIR with a gain step of 15 dB, providing IIP3 improvement of 18 dB and NF degradation of only 6 dB. Moreover, design trade-offs are carefully considered in designing the baseband circuit, which provides wide gain tuning and bandwidth accuracy with a DC offset residual less than 6 mV. The measured maximum SNR values are better than 30 dB over wide input power levels, ensuring robust reception in a mobile environment. All circuit blocks are operated at 1.2 V. As a result, the tuner consumes power as low as 114 mW in the continuous mode. This compact tuner supports both UHF and L- bands, and occupies only 7.2 mm2 die area.
Identification of Plasmolipin as a Major Constituent of White Matter Clathrin‐Coated Vesicles

Abstract: We have isolated and characterized coated vesicles from bovine white matter and compared them to those isolated from gray matter. The virtual absence of synaptic vesicle antigens in the white matter coated vesicles indicates they are distinct from those found in gray matter and from vesicles derived from synaptic membranes. The white matter coated vesicles also lack compact myelin components, e.g., the myelin proteolipid, galactocerebroside, and sulfatides, as well as the periaxolemmal myelin marker myelin‐associated glycoprotein. On the other hand, these vesicles contain 2′,3′‐cyclic nucleotide phosphohydrolase. The vesicles also contain high levels of plasmolipin, a protein present in myelin and oligodendrocytes. Plasmolipin was found to be four to five times higher in white matter coated vesicles than in gray matter coated vesicles. Based on western blot quantitation, the concentration of plasmolipin in white matter coated vesicles is 3–4% of the vesicle bilayer protein. These studies indicate that a significant proportion of coated vesicles from white matter may be derived from unique membrane domains of the myelin complex or oligodendroglial membrane, which are enriched in plasmolipin.
Neural network based adaptive dynamic surface control for flight path angle

A neural network based adaptive dynamic surface control is proposed for the aircraft longitudinal flight path angle. The dynamic surface control method eliminates the problem of “explosion of complexity” existing in traditional backstepping approach with the introduction of low pass filters. Radial basis function (RBF) neural networks are used to approximate the unknown nonlinearities of the model online. Adaptive laws are designed to estimate the weight values of the neural networks and unknown parameters. From Lyapunov stability analysis, it is shown that the control strategy can guarantee the semi-global practical tracking and arbitrarily small tracking error by adjusting the controller parameters. Simulation results are presented to validate the good tracking performance and strong adaptability of the control system.
Content-Based Retrieval of Multimedia Information

The recent information explosion has led to massively increased demand for multimedia data storage and retrieval techniques. Content-based retrieval is an important alternative and complement to the traditional keyword-based searching for multimedia data and can greatly enhance information management. For the last ten years, the Biomedical and Multimedia Information Technology (BMIT) Group and recently the Center for Multimedia Signal Processing (CMSP) have conducted systematic studies and research activities on this topic. Some of the works relating to content-based image/video retrieval and their applications are briefly presented in this paper.
Coevolution in bicoid‐dependent promoters and the inception of regulatory incompatibilities among species of higher Diptera

SUMMARY To what extent and in what way do gene promoters and their transacting regulatory proteins coevolve? In this and in earlier publications we show that the Bicoid‐dependent promoters of the segmentation genes hunchback and tailless in species of higher Diptera (Drosophila, Musca, Calliphora, and Lucilia) are different with respect to the copy number, spacing, sequence, and orientation of Bicoid binding sites. At the same time there are significant amino acid differences in the Bicoid homeodomain. To test these interspecific differences, we used a series of functional assays, starting with the analysis of Bicoid binding affinities of individual sites, through to transgene rescue experiments, to compare within‐species with between‐species mixtures of Bicoid homeo‐ domains and hunchback or tailless promoters. We observed that components taken from different species interact with less efficiency compared with those taken from within the same species. Our interpretation is that such interspecific incompatibilities are a consequence of interactive genetic elements coevolving one with another, hence maintaining functional compatibility within each species. At the same time such a process allows differences to accumulate between species regarding the precise molecular basis whereby the common function is effected.
Motion control of a tendon-based parallel manipulator using optimal tension distribution

This paper presents the motion control of a six degree-of-freedom tendon-based parallel manipulator, which moves a platform with high speed using seven cables. To control the motion of the platform along desired trajectories in space, nonlinear feedforward control laws in the cable length coordinates are used. Taking account of the effect of redundancy on actuation, the optimal tension distribution should be considered to the advantage of the control laws. Using a method based on the analysis of the workspace condition, tension constraints and limiting torque constraints of actuators, an analytical solution for optimum tension distribution was found and used to compute the force in each cable for compensation of dynamic errors. It is experimentally demonstrated that the proposed control laws reduce the energy consumption of the actuators and satisfy the path tracking accuracy.
Moxifloxacin versus Levofloxacin for Uncomplicated Skin and Skin Structure Infections: Treatment Durations, Failures, and Charges

• Objective: The approved therapy durations for the once-daily fluoroquinolones moxifloxacin and levofloxacin are 7 days and 7 to 10 days, respectively. We studied whether these labeling differences translated into differences in treatment duration, failure rates, or treatment charges in the treatment of uncomplicated skin and structure infections. • Design: Retrospective database study of insurance claims. • Setting and participants: 1896 patients treated in community settings throughout the United States between April 2001 and June 2002 for 1926 episodes of uncomplicated skin infection. • Measurements: Duration of the initial moxifloxacin or levofloxacin prescription, treatment failure rates, duration of all antibiotic prescriptions, and treatment charges. Analyses were adjusted for age, sex, comorbidities, infection type, diabetic status, topical antibiotic use, and other factors. • Results: 130 moxifloxacin treatment episodes from 129 patients and 1796 levofloxacin treatment episodes from 1767 patients were analyzed. The adjusted mean duration of the initial prescription was 0.9 days shorter for patients treated with moxifloxacin than for those treated with levofloxacin (P < 0.01). There was no statistically significant difference in treatment failure rates, duration of all antibiotic prescriptions, or charges between patients who initiated therapy with moxifloxacin or levofloxacin. • Conclusion: Initial moxifloxacin therapy was used for fewer days than initial levofloxacin therapy, which is consistent with dosing and administration recommendations contained in each product’s label. Shorter duration of initial therapy did not result in an increase in the odds of a treatment failure for patients treated with moxifloxacin.
Rescue of Pulmonary Hypertension with an Oral Sulfonamide Antibiotic Sulfisoxazole by Endothelin Receptor Antagonistic Actions

Pulmonary hypertension (PH) is a disease of unknown etiology that ultimately causes right ventricle heart failure with a lethal outcome. An increase in circulating endothelin (ET)-1 levels may contribute to disease progression. This study aimed to examine the possible effects of an orally active ET receptor antagonist, sulfisoxazole (SFX), for the rescue of PH, right ventricular hypertrophy, and eventual right ventricular failure. PH rats (single injection of monocrotaline [MCT]) were treated with an ET antagonist, SFX, an orally active sulfonamide antibody. Effects of SFX on PH rats were assessed in terms of survival rate, pulmonary artery blood pressure (PABP), autonomic nerve activity, and atrial natriuretic peptide (ANP) concentration in right ventricular myocytes and plasma. SFX did not change systemic blood pressure, however, it significantly suppressed the elevation of PABP. SFX maintained the derangement of autonomic nerve control, blunted an increase in ANP in myocytes and plasma, and significantly improved survival in right heart failure and/or related organs dysfunction in PH rats. The ET antagonistic action of the antimicrobial agent, SFX, was experimentally confirmed for treatment of PH in rats.
Prospective Cohort Analysis of the Predictive Validity of a Screening Instrument for Severe Restrictions of Work Ability in Patients with Musculoskeletal Disorders

ObjectiveThe aim of this study was to determine whether the Screening-Instrument zur Feststellung des Bedarfs an medizinisch-beruflich orientierter Rehabilitation (SIMBO) screening instrument can identify persons with a high work disability risk. DesignPatients with chronic musculoskeletal disorders and participation in a rehabilitation program were included in the analysis. Data were collected by questionnaires at admission and at the 6-mo follow-up. Failed return to work (RTW; i.e., unemployment or active employment with sick leave of >12 wks in the follow-up) was the primary outcome. Additional outcome data were obtained from the physician’s discharge form (e.g., assessment of work ability). Receiver operating characteristic analyses and logistic regression models were used to analyze the data. ResultsValid data were available for 1755 participants. Of these, 25% reported failed RTW. The area under the curve of the SIMBO score predicting failed RTW was 0.81 (0.79–0.83). The optimal cutoff to identify failed RTW was 23 points (of 100). The odds of failed RTW, unemployment, and sick leave of more than 12 wks were increased 12, 11, and 10 times for the persons with a SIMBO score of 23 points or greater compared with the persons with lower SIMBO scores. The odds of reduced work time capacity were increased 21 times. ConclusionsThe SIMBO predicts work disability in patients with chronic musculoskeletal disorders. Further research should focus on its predictive validity in patients with other disorders and within other rehabilitation systems.
A Modified Nonparametric Weight Feature Extraction Using Spatial and Spectral Information

Feature extraction is often applied for dimensionality reduction in hyperspectral data classification problems to mitigate the Hughes phenomenon. Some studies had proven that nonparametric weighted feature extraction (NWFE) is a powerful tool to extract well-described features for classification. NWFE concentrates only on the separability of spectral data, however, in many remotely sensed images, objects on the ground are much greater than one pixel. Hence, neighboring pixels are more likely to belong to the same class and form a homogeneous region. We present a scheme to fuse spatial information into NWFE, and from the real data experiments, we can find the proposed method outperforms the original NWFE.
Thirteen Ways to Write an Abstract

The abstract is a crucial component of a research article. Abstracts head the text—and sometimes they can appear alone in separate listings (e.g., conference proceedings). The purpose of the abstract is to inform the reader succinctly what the paper is about, why and how the research was carried out, and what conclusions might be drawn. In this paper we consider the same (or a similar) abstract in 13 different formats to illustrate the strengths and weaknesses of each approach.
Modelizacion de series temporales multiples en espacio de estados, analisis de procesos no estacionarios y cointegracion

El trabajo de investigacion se centra en el estudio de series temporales multiples no estacionarias representadas en espacio de estados. Se abordan las dificultades encontradas en la representacion autorregresiva y/o de medias moviles para tales procesos y se desarrollan algoritmos que permitan su tratamiento en una representacion markoviana. Asi, tras la exposicion de los fundamentos de tal metodologia y una breve sintesis de los avances recientes en la literatura especializada, se tratan los problemas relacionados con la deteccion y tratamiento de tendencias no deterministas en los datos, asi como los relacionados con la obtencion de posibles factores comunes de tendencia y cointegracion entre las series individuales. Para ello, se plantea una estrategia secuencial de contrastacion del numero de posibles tendencias comunes, basado en cocientes de valores singulares obtenidos de cierta matriz relacionada con las matrices de autocorrelacion del proceso. Se obtienen tablas de valores criticos a los niveles de significacion usuales para la elaboracion de tales contrastes.
A Phylogenetically Conserved Hairpin-Type 3′ Untranslated Region Pseudoknot Functions in Coronavirus RNA Replication

ABSTRACT Secondary and tertiary structures in the 3′ untranslated region (UTR) of plus-strand RNA viruses have been postulated to function as control elements in RNA replication, transcription, and translation. Here we describe a 54-nucleotide (nt) hairpin-type pseudoknot within the 288-nt 3′ UTR of the bovine coronavirus genome and show by mutational analysis of both stems that the pseudoknotted structure is required for the replication of a defective interfering RNA genome. The pseudoknot is phylogenetically conserved among coronaviruses both in location and in shape but only partially in nucleotide sequence, and evolutionary covariation of bases to maintain G · U pairings indicates that it functions in the plus strand. RNase probing of synthetic transcripts provided additional evidence of its tertiary structure and also identified the possible existence of two conformational states. These results indicate that the 3′ UTR pseudoknot is involved in coronavirus RNA replication and lead us to postulate that it functions as a regulatory control element.
Corticolimbic changes in acetylcholine and cyclic guanosine monophosphate in the Flinders Sensitive Line rat: a genetic model of depression

Objective: Depression is suggested to involve disturbances in cholinergic as well as glutamatergic pathways, particularly the N-methyl-d-aspartate receptor-mediated release of nitric oxide (NO) and cyclic guanosine monophosphate (cGMP). The aim of this study was to determine whether the Flinders Sensitive Line (FSL) rat, a genetic model of depression, presents with corticolimbic changes in basal acetylcholine (ACh) levels and NO/cGMP signalling. Methods: Basal levels of nitrogen oxides (NOx) and both basal and l-arginine-stimulated nitric oxide synthase (NOS) formation of l-citrulline were analysed in hippocampus and frontal cortex in FSL and control Flinders resistant line (FRL) rats by fluorometric and electrochemical high-performance liquid chromatography, respectively. In addition, ACh and cGMP levels were analysed by liquid chromatography tandem mass spectrometry and radioimmunoassay, respectively. Results: Significantly elevated frontal cortical but reduced hippocampal ACh levels were observed in FSL versus FRL rats. Basal cGMP levels were significantly reduced in the frontal cortex, but not hippocampus, of FSL rats without changes in NOx and l-citrulline, suggesting that the reduction of cGMP follows through an NOS-independent mechanism. Conclusions: These data confirm a bidirectional change in ACh in the frontal cortex and hippocampus of the FSL rat, as well as provide evidence for a frontal cortical ACh-cGMP interaction in the depressive-like behaviour of the FSL rat.