Miracle-dz/UniFAR-FTUs huggingface dataset:
An Adaptive Sliding Mode Control based Maximum power point tracking method for a PV stand-alone system

This paper presents a photovoltaic (PV) system with an adaptive sliding mode control based maximum power point tracking (MPPT) algorithm. The main aim of this work is to maximize power extraction from the photovoltaic generator. A novel method, which is able to achieve this aim, is presented by using an adaptive sliding mode controller (ASMC) that drives a boost converter connected between the PV generator and the load. Both robustness and stability of the ASMC controller are investigated against weather changing conditions. Simulation results with real data, under MATLAB-SIMULINK, are given to demonstrate the effectiveness of the proposed approach.
High‐resolution genomic screening in mantle cell lymphoma—specific changes correlate with genomic complexity, the proliferation signature and survival

Mantle cell lymphoma (MCL) is characterized by the t(11;14)(q13;q32) and numerous copy number aberrations (CNAs). Recently, gene expression profiling defined a proliferation gene expression signature in MCL where high scores predict shorter survival. We investigated 31 MCL cases using high‐density single nucleotide polymorphism arrays and correlated CNA patterns with the proliferation signature and with clinical data. Many recurrent CNAs typical of MCL were detected, including losses at 1p (55%), 8p (29%), 9q (29%), 11q (55%), 13q (42%) and 17p (32%), and gains at 3q (39%), 8q (26%), 15q (23%) and 18q (23%). A novel deleted region at 20q (16%) contained only one candidate gene, ZFP64, a putative tumor suppressor. Unsupervised clustering identified subgroups with different patterns of CNAs, including a subset (19%) characterized by the presence of 11q loss in all cases and by the absence of 13q loss, and 3q and 7p gains. Losses at 1p, 8p, 13q and 17p were associated with increased genomic complexity. High proliferation signature scores correlated with increased number of large (>15 Mbp) CNAs (P = 0.03) as well as copy number gains at 7p (P = 0.02) and losses at 9q (P = 0.04). Furthermore, large/complex 13q losses were associated with improved survival (P < 0.05) as were losses/copy number neutral LOH at 19p13 (P = 0.01). In summary, this high‐resolution genomic analysis identified novel aberrations and revealed that several CNAs correlated with genomic complexity, the proliferation status and survival. © 2010 Wiley‐Liss,Inc.
Towards highly-tuned mobility in multiple domains with a dynamical legged platform

As mobile robots become more commonly utilized in everyday applications, the tasks they are given will often require them to quickly traverse unprepared and varied environments. While traditional mobile platforms may falter under such conditions, animals utilize distinct locomotion modalities such as running, jumping, or climbing, to adroitly negotiate a wide variety of challenging and changing terrains. Due to limitations including available on-board power, legged robots have struggled to match the speed of these animals, even in a single mode of transport. In this paper we experimentally investigate the synergies and trade-offs in developing a dynamical legged robot capable of both running and climbing. We utilize bio-inspired ‘templates’ or reduced-order models of motion to identify how the dynamics change from running to climbing and seek to identify a minimal set of robotic adjustments necessary to switch locomotion modalities. This template-based design methodology is explained and the resultant robot behavior in each domain is characterized. We show that using a trotting gait, the platform demonstrates running speeds of up to 0.67 ms−1 on level ground and climbing speeds of up to 0.43 ms−1on near-vertical surfaces (and up to 0.16 ms−1 on vertical surfaces) while exhibiting dynamical behaviors comparable to that of the inspirational models.
The Transcription Factors GATA4 and GATA6 Regulate Cardiomyocyte Hypertrophy in Vitro and in Vivo *

The zinc finger-containing transcription factors GATA4 and GATA6 are important regulators of basal and inducible gene expression in cardiac and smooth muscle cell types. Here we demonstrate a direct functional role for GATA4 and GATA6 as regulators of cardiomyocyte hypertrophic growth and gene expression. To model the increase in endogenous GATA4 and GATA6 transcriptional activity that occurs in response to hypertrophic stimulation, each factor was overexpressed in cardiomyocytes using recombinant adenovirus. Overexpression of either GATA4 or GATA6 was sufficient to induce cardiomyocyte hypertrophy characterized by enhanced sarcomeric organization, a greater than 2-fold increase in cell surface area, and a significant increase in total protein accumulation. In vivo, transgenic mice with 2.5-fold overexpression of GATA4 within the adult heart demonstrated a slowly progressing increase in heart to body weight ratio, histological features of cardiomyopathy, and activation of hypertrophy-associated genes, suggesting that GATA factors are sufficient regulators of cardiomyocyte hypertrophy in vitro and in vivo. To evaluate the requirement of GATA factors as downstream transcriptional mediators of hypertrophy, a dominant negative GATA4-engrailed repressor fusion-encoding adenovirus was generated. Expression of GATA4-engrailed blocked GATA4- and GATA6-directed transcriptional responses and agonist-induced cardiomyocyte hypertrophy, demonstrating that cardiac-expressed GATA factors are necessary mediators of this process.
Analysis and Optimization of LLC Resonant Converter With a Novel Over-Current Protection Circuit

A novel over-current protection (OCP) method for a LLC resonant converter has been proposed in this paper. This method is very attractive for its inherent current limit ability, especially under short-circuit condition. Combined with the frequency increasing method, good current limit features can be achieved. Compared to the conventional LLC resonant converter with frequency increasing method, LLC with the proposed OCP method can reduce the maximum frequency to an acceptable value. Detailed theoretical analysis and optimization design considerations have been presented. An experimental prototype converter based on the proposed method has been built up to verify the theoretical analysis. Experimental results meet the theoretical analysis very well
Robust L_p-Norm Decoding for BICM-Based Secondary User Systems

The frequency bands used by secondary user systems such as cognitive radio and ultra-wideband (UWB) systems are subject to various forms of non-Gaussian noise and interference including co-channel and narrowband interference caused by the primary user and other secondary users as well as man-made impulsive noise. For secondary user systems employing popular bit-interleaved coded modulation (BICM) we propose a robust Lp-norm metric for Viterbi decoding to overcome the harmful effects of non-Gaussian noise and interference. For the resulting system, we derive an approximate upper bound on the bit error rate (BER) and a general analytical expression for the asymptotic BER valid for all practically relevant types of fading, including Rayleigh, Ricean, Nakagami-m, Nakagami-q, and Weibull fading, and all types of noise and interference with finite moments. Simulation and analytical results show that, in non-Gaussian noise and interference, the proposed Lp-norm metric yields large performance gains over the conventional L2-norm metric and outperforms erasure decoding.
MalY of Escherichia coli is an enzyme with the activity of a beta C-S lyase (cystathionase)

The Escherichia coli maltose system consists of a number of genes whose products are involved in the uptake and metabolism of maltose and maltodextrins. MalT is the central positive gene activator of the regulon and is, together with the cyclic AMP-catabolite gene activator protein system, necessary for the expression of the maltose genes. Expression of malY, a MalT-independent gene, leads to the repression of all MalT-dependent genes. We have purified MalY to homogeneity and found it to be a pyridoxal-5-phosphate-containing enzyme with the enzymatic activity of a beta C-S lyase (cystathionase). MalY is a monomeric protein of 42,000 to 44,000 Da. Strains expressing MalY constitutively abolish the methionine requirement of metC mutants. The enzymatic activity of MetC, the cleavage of cystathionine to homocysteine, ammonia, and pyruvate, can be catalyzed by MalY. However, the cystathionase activity is not required for the function of MalY in repressing the maltose system. By site-directed mutagenesis, we changed the conserved lysine residue at the pyridoxal phosphate binding site (position 233) of MalY to isoleucine. This abolished beta C-S lyase activity but not the ability of the protein to repress the maltose system. Also, the overexpression of plasmid-encoded metC did not affect mal gene expression, nor did the deduced amino acid sequence of MetC show homology to that of MalY.
Address-based crowdsourcing radio map construction for Wi-Fi positioning systems

A radio map is a collection of fingerprints and collected location information. To build more accurate Wi-Fi positioning system (WPS), a more precise radio map should be prepared in advance. Despite GPS signals are usually unreachable in most indoor venues, GPS signals are commonly used as reference locations to tag the collected fingerprints. As a result, WPS has not been able to achieve high performance in accuracy indoors, even if the place is rich in Wi-Fi signals. This paper introduces a novel method to construct a radio map without any use of GPS signals. Users' home or office address is used instead to tag the locations of collected Wi-Fi signals. Since the method utilizes Wi-Fi signals collected indoors, a more precise radio map construction is possible. For evaluation, we tested the method at four deliberately selected residential and downtown areas in Daejeon and Seoul, Korea. Once the data collection rate rises above 50%, the average error distance was within 10m or less. This indicates that address-based crowdsourcing radio map construction can be an effective means to construct global-scale but precise radio maps at low cost.
An Empirical Analysis of the Money Demand Function in Asean-5

This paper investigates the dynamic of relationship between real money balances and real income, lending rates, interest rates and inflation rate in ASEAN-5, namely Indonesia, Malaysia, Philippine, Singapore and Thailand. Using sample period for each country spans from 1987 month one through 2007 month four, the empirical results indicate that (1) cointegration technique – two step Engle Granger (1987) and error correction model (ECM) clearly show that there exists a long run relationships between real money balances and its determinants and (2) the ECM analysis has provided a support to the short-run relationships between M2 and real income, lending rates, interest rates and inflation rate for ASEAN-5.
How to make Ontologies self-building from Wiki-Texts

While it used to be satisfactory that sea r ch applications used to look up simple keywords in the past, nowadays a sea rch engine is increasingly expected to be able performing sema ntic sea rch as well. This leads to an intensified research on ontologies supporting these applications. Users might only have a vague idea of the exact keywords to the content they seek, especially when it comes to technical or subject-specific topics and professional expertise is needed. A domain-specific ontology can support the user suggesting differentiated or alternative keywords for his query. Nevertheless, building an ontology containing expert knowledge is effortful and domain experts normally do not have sufficient skills how to build an ontology. Therefore, it is desirable to make an ontology automatically build and extend itself from alrea dy ava ilable information, such as wiki-texts. We developed a text mining component which automatically derives an ontology from collaborative texts written by scientific experts. Our component is used in a sea rch application of an informa tion system on energy research.
Community physicians' strategies for patients with medically unexplained symptoms.

BACKGROUND AND OBJECTIVES This qualitative study examined the management strategies that community primary care physicians use for patients with medically unexplained symptoms (MUS). METHODS Volunteer community physicians identified patients with chronic MUS. The physicians and patients were interviewed separately about management strategies used and their effectiveness. Thematic analyses were used to categorize these strategies. RESULTS Thirty-six physicians and 49 of their patients completed interviews. Physician strategies considered effective by physicians and patients included medical treatment, exploring causes of symptoms with tests and referrals, attentive listening, validating complaints, demonstrating commitment over time (eg, assuring patients of continued care, allowing extended office visits, and returning phone calls), providing clear explanations of symptoms and management, and providing explanatory models for the linkage between psychosocial factors and physical symptoms. Strategies used that conflict with published recommendations included ordering potentially unnecessary diagnostic tests, scheduling patients on demand, and prescribing narcotics. Physicians expressed concerns about these strategies but considered the benefits for specific patients worth the costs and risks. CONCLUSIONS Physicians used some strategies recommended in the medical literature and others not recommended. The ability to effectively implement certain strategies may depend on having a long-term relationship with a patient and a health care environment that permits extensive patient-physician interaction.
Guidelines for laboratory diagnosis of factor XIII deficiency

Factor XIII (FXIII) deficiency is an extremely rare hemorrhagic disorder with an approximate worldwide incidence of one per two million. With current tests, diagnosis of this disease can be made more precisely. However, factors such as the number of patients with FXIII deficiency (FXIIID), available diagnostic coagulation tests and the number of molecular studies have affected the diagnosis of FXIIID in different parts of the world. Various laboratory approaches can be used, including screening and diagnosis of the disorder in countries with a relatively high rate of FXIIID and recurrent mutation(s) with a simple polymerase chain reaction-restriction fragment length polymorphism analysis or polymerase chain reaction-sequencing for detection of one or a few specific mutations. In other countries, two different laboratory approaches can be used, depending on available coagulation tests. In less-equipped coagulation laboratories, the clot solubility test remains the only diagnostic test for FXIIID. Even in these countries, at least one referral laboratory should perform FXIII activity and, if possible, confirmation of FXIIID by molecular analysis. In countries with well equipped coagulation laboratories, FXIII activity should be used to screen suspected FXIIID patients; more specific tests such as molecular analysis should be used for confirmation. This study suggests a simple, reliable and flexible algorithm for early diagnosis of FXIIID, and may, with one-time diagnosis of FXIIID, reduce the rate of morbidity and mortality in patients with the disorder.
The New Cabinet Crisis Management Center and the Leadership of the Prime Minister

In May 2001, a cabinet crisis management center was set up below the prime minister's new official residence. It is from here that Japan's national crises are now to be managed. In an era of constant flux, questions over the circumstances surrounding Japan's strategic security are being raised. Clearly, the structure of crisis management and legislation are crucial for a nation'ssecurity. In this article, Lt. Gen. Toshiyuki Shikata of the Japan Ground Self-Defense Force (retired) and professor of Law at Teikyo University, examines 30 international and domestic crises that Japan had to deal with in which the leadership of the prime minister determined the outcome. He describes the history of Japanese crisis management, pointing out the current problems and argues that in a post-Cold War era, Japan needs to confront the discrepancies in the structure of its security if it wishes to become a credible member of the international community.
Design and implementation of wireless Smart-home sensor network based on ZigBee protocol

We propose a system of wireless smart-home sensor network based on ZigBee and PSTN remote control using PIC18LF4620 SCM and 2.4G RF transceiver module. The network configuration, communication protocol, software and hardware implementation process of our system are described in this paper. Through using the PSTN network for the long-haul network and ZigBee technology for the indoor network, our system fulfils home-remote-control and auto-alarm, expediently.
Oxidative Stress and Endometriosis: A Systematic Review of the Literature

Endometriosis is one of the most common gynaecologic diseases in women of reproductive age. It is characterized by the presence of endometrial tissue outside the uterine cavity. The women affected suffer from pelvic pain and infertility. The complex etiology is still unclear and it is based on three main theories: retrograde menstruation, coelomic metaplasia, and induction theory. Genetics and epigenetics also play a role in the development of endometriosis. Recent studies have put the attention on the role of oxidative stress, defined as an imbalance between reactive oxygen species (ROS) and antioxidants, which may be implicated in the pathophysiology of endometriosis causing a general inflammatory response in the peritoneal cavity. Reactive oxygen species are intermediaries produced by normal oxygen metabolism and are inflammatory mediators known to modulate cell proliferation and to have deleterious effects. A systematic review was performed in order to clarify the different roles of oxidative stress and its role in the development of endometriosis. Several issues have been investigated: iron metabolism, oxidative stress markers (in the serum, peritoneal fluid, follicular fluid, peritoneal environment, ovarian cortex, and eutopic and ectopic endometrial tissue), genes involved in oxidative stress, endometriosis-associated infertility, and cancer development.
Efficient Rhodamine B Removal Using Acidand
Alkaline-Activated Musa paradisiaca
Biochar

Musa paradisiaca char was subjected to acid and alkaline treatment in order to prepare highly porous and efficient adsorbents. Prepared adsorbents were subjected to various characterizations viz surface morphology using a scanning electron microscopic (SEM), surface functional group using the Fourier transformed infrared spectroscopic (FTIR) analysis, and Brunauer-Emmett-Teller (BET) surface area among others. Adsorbents were subsequently used for the uptake of Rhodamine B (RhB) from aqueous solution, and adsorption data were tested with isothermal and kinetics models. BET surface area of 985 m2 /g was obtained for alkaline-treated Musa paradisiaca. SEM revealed large pores on treated biomass and functional groups analysis revealed functional groups suitable for sorption. The prepared adsorbents were found to be effective in the uptake of Rhodamine B, with more than 90% removal in some cases. Maximum adsorption was obtained at pH 4 for both adsorbents. Equilibrium adsorption data fitted best into the Langmuir adsorption isotherm with maximum monolayer adsorption capacity of 7.003 mg/g and 6.878 mg/g for acid-treated biomass and alkaline-treated biomass, respectively. Pseudo second-order kinetics best described the adsorption kinetic data of the two adsorption systems.
ProtVirDB: a database of protozoan virulent proteins

UNLABELLED ProtVirDB is a comprehensive and user-friendly web-based knowledgebase of virulent proteins belonging to protozoan species. The database will facilitate research and provide an integrated platform for comparative studies of virulent proteins in different parasitic protozoans and organize them under a unifying classification schema with functional categories. Remarkably, one-third of the protein sequences in the database showed presence of either mono- or hetero-repeats, or both concomitantly--hence reiterating the importance of repeats in parasite virulence mechanisms. A number of useful bioinformatics tools including BLAST and tools for phylogenetic analysis are integrated with the database. With the rapidly burgeoning interest in the pathogenesis mechanisms of protozoans and ongoing genome sequencing projects, we anticipate that the database will be a useful tool for the research community. AVAILABILITY http://bioinfo.icgeb. res.in/protvirdb. SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.
Lifetime prevalence of mental health disorders and delay in treatment following initial onset: evidence from the Northern Ireland Study of Health and Stress

Background The current study provides the first epidemiological estimates of lifetime mental disorders across NI based on DSM-IV criteria. Risk factors, delays in treatment and the experience of conflict are also examined. Method Nationally representative face-to-face household survey of 4340 individuals aged ⩾18 years in NI using the Composite International Diagnostic Interview. Analyses were implemented using SAS and STATA software. Results Lifetime prevalence of any disorder was 39.1% while projected lifetime risk was 48.6%. Individuals who experienced conflict were more likely to have had an anxiety, mood or impulse-control disorder. Treatment delays were substantial for anxiety and substance disorders. Conclusions Results from this study show that mental disorders are highly prevalent in Northern Ireland. The elevated rates of post-traumatic stress disorder in relation to other countries and the association of living ‘in a region of terror’ disorders suggests that civil conflict has had an additional impact on mental health. Given substantial delays in treatment, further research is required to investigate the factors associated with failure and delay in treatment seeking.
Fabrication of mass sensitive piezoresistive cantilever structure for biochemical detection

This paper reports a mechanical micro-structure MEMS (Micro-Electricomechanical System) based sensor fabrication using CMOS platform for biochemical detection. The structure is monolithically integrated with the detection circuit/ readout circuit. Silicon dioxide layer is implemented in the current MEMS structure as an absorption layer for bio targets by CMOS process tools. Result shows that the fabricated piezoresistive cantilever MEMS have linear relation output voltage respond with the different weight of DNA applied.