Miracle-dz/UniFAR-FTUs huggingface dataset:
[Factors modulating the efficacy of psychosocial treatment in children with attention deficit hyperactivity disorder].

INTRODUCTION Treatment of patients with attention deficit hyperactivity disorder (ADHD) in recent decades has not been in one way only but rather by using various approaches (pharmacological, behavioural, cognitive, etc.). It is becoming increasingly obvious that hyperactivity requires a multi-disciplinary approach with clear instructions for parents and teachers. Teachers need most information regarding ADHD and its treatment so as to use the techniques which are most effective for directing behaviour in the classroom. OBJECTIVES This study had two objectives. Firstly, we wished to analyze the efficacy of a psychosocial programme with multiple components (programme for individualized treatment in the classroom) in 50 children with ADHD using the methodology of significant clinical change analysis of Jacobson and Truax (1991). Secondly, to try to define the variables which may modulate cognition and behaviour and possibly affect the results and success or failure of the programme. DEVELOPMENT Regarding the first objective, it was found that a much more significant proportion improved after following the hyperactivity/impulsivity programme, in the opinions of parents and teachers. Regarding the second objective the results show that the variables which may modulate the efficacy of treatment are deficits in inhibitory control, anxiety, disobedience, isolation and social inadaptation.
Dynamics of cancer progression and suppression: A novel evolutionary game theory based approach

In this paper, a novel mathematical approach is proposed for the dynamics of progression and suppression of cancer. We define mutant cell density, ρμ (μ × ρ), as a primary factor in cancer dynamics, and use logistic growth model and replicator equation for defining the dynamics of total cell density (ρ) and mutant fraction (μ), respectively. Furthermore, in the proposed model, we introduce an analytical expression for a control parameter D (drug), to suppress the proliferation of mutants with extra fitness level σ. Lastly, we present a comparison of the proposed model with some existing models of tumour growth.
Robust lossless data hiding scheme

This paper presents a robust lossless data hiding scheme. The original cover image can be recovered without any distortion after data extraction if the stego-image remains intact, and conversely, the hidden data can still be extracted correctly if the stego-image goes through JPEG compression to some extent. A cover image is divided into a number of non-overlapping blocks, and the arithmetic difference of each block is calculated. By shifting the arithmetic difference value, we can embed bits into the blocks. The shift quantity and shifting rule are fixed for all blocks, and reversibility is achieved. Furthermore, because the bit-0- and bit-1-zones are separated and the particularity of the arithmetic differences, minor changes applied to the stego-image generated by non-malicious attacks such as JPEG compression will not cause the bit-0- and bit-1-zones to overlap, and robustness is achieved. The new embedding mechanism can enhance embedding capacity and the addition of a threshold can make the algorithm more robust. Experimental results showed that, compared with previous schemes, the performance of the proposed scheme is significantly improved.
The Effectiveness of a School-Based Adolescent Depression Education Program

In an effort to decrease the suicide rate in adolescents, many interventions have focused on school-based suicide prevention programs. Alternatively, depression education in schools might be effective in decreasing the morbidity, mortality, and stigma associated with adolescent depression. The Adolescent Depression Awareness Program (ADAP) developed a 3-hour curriculum to teach high school students about the illness of depression. The purpose of this study was to assess the effectiveness of the ADAP curriculum in improving high school students’ knowledge about depression. From 2001 to 2005, 3,538 students were surveyed on their knowledge about depression before and after exposure to the ADAP curriculum. The number of students scoring 80% or higher on the assessment tool more than tripled from pretest to posttest (701 to 2,180), suggesting the effectiveness of the ADAP curriculum. Further study and replication are required to determine if improved knowledge translates into increased treatment-seeking behavior.
Financial Innovation, Stock Market Development, and Economic Growth: An Application of ARDL Model

This study aims to explore the relationship between economic growth, financial innovation, and stock market development of Bangladesh for the period 1980–2016. To investigate long-run cointegration, this study used the autoregressive distributed lagged (ARDL) bounds testing approach. In addition, the Granger-causality test is used to identify directional causality between research variables under the error correction term. Study findings from the ARDL bound testing approach confirm the existence of a long-run association between financial innovation, stock market development, and economic growth. Furthermore, the findings from the Granger-causality test support bidirectional causality between financial innovation, economic growth and stock market development, and economic growth both in the long run and short run. These findings support the theory that market-based financial development and financial innovation in the financial system can spur economic development.
SMS text messaging as a means of increasing recall of therapy goals in brain injury rehabilitation: A single-blind within-subjects trial

A single-blind within-subjects trial was used to test the efficacy of sending SMS text messages to patients with a traumatic brain injury as a means of improving their recall of rehabilitation goals. Eleven participants were recruited from two community-based rehabilitation centres and were sent text messages relating to three randomly selected goals from a selection of six current goals three times per day for 14 days. Participants’ recall of their rehabilitation goals was assessed at baseline, seven days, and 14 days via free recall and cued recall procedures. Results showed that goals in the “text” condition were recalled better than goals in the “no text” condition. Practical applications and extensions are discussed.
An insertional mutant of epidermal growth factor receptor allows dissection of diverse receptor functions.

Cultured NIH‐3T3 cells devoid of endogenous EGF‐receptors were transfected with cDNA constructs encoding normal human EGF‐receptor and with a construct encoding an insertional mutant of the EGF‐receptor containing four additional amino acids in the kinase domain after residue 708. Unlike the wild‐type receptor expressed in these cells which exhibits EGF‐stimulatable protein tyrosine kinase activity, the mutant receptor lacks protein tyrosine kinase activity both in vitro and in vivo. Despite this deficiency the mutant receptor is properly processed, it binds EGF and it exhibits both high and low affinity binding sites. Moreover, it undergoes efficient EGF‐mediated endocytosis. However, EGF fails to stimulate DNA synthesis and is unable to stimulate the phosphorylation of S6 ribosomal protein in cells expressing this receptor mutant. Hence, it is proposed that the protein tyrosine kinase activity of EGF‐receptor is essential for the initiation of S6 phosphorylation and for DNA synthesis induced by EGF. However, EGF‐receptor processing, the expression of high and low affinity surface receptors and receptor internalization, require neither kinase activity nor receptor autophosphorylation. Interestingly, phorbol ester (TPA) fails to abolish the high affinity state and is also unable to stimulate the phosphorylation of this receptor mutant. This result is consistent with the notion that kinase‐C phosphorylation of EGF‐receptor is essential for the loss of high affinity EGF‐receptors caused by TPA.
Structural Requirements for the Anti-Inflammatory Activity of Natural Triterpenoids

In order to establish the possible relationship between their chemical structures and pharmacological properties, the oral and topical anti-inflammatory activities of ten triterpenoids belonging to the lupane, oleanane, and ursane series, were evaluated. All triterpenoids were remarkably active against the edema produced by TPA. While the basic carbon skeleton has no influence on the activity, the presence of a C-28 or C-30 carboxylic group and an alcoholic group at C-28 increases the activity in carrageenan- and EPP-induced edemas, respectively.
Immigrants' Perceptions of their Experiences in Integrating into Communities in the Lower Mainland of British Columbia

Immigrants integrating into a new culture and/or society might bring certain expectations, perceptions and hopes with themselves. Although generally considered fairly normal and expected for the most part, these expectations can create problems for oneself and for others around the individual immigrant. This thesis will look into the perceptions of the immigrants integrating into the Lower Mainland of British Columbia. The immigrants discussed and studied in this particular thesis are from Pakistan, one of the many different communities that are a part of the Lower Mainland region of British Columbia. The participants selected were five families that are part of the Pakistani community in the Tri-cities area of the Lower Mainland of British Columbia. These families were selected because they were known to the interviewee or they were known through a common friend. A questionnaire was created and the immigrants were interviewed using that questionnaire; some participants completed the questionnaire on their own, without being interviewed. The research was conducted so that a better understanding would be attained by educators and others in lower Mainland regarding the issues faced by the immigrants in the Lower Mainland of British Columbia and as well as their perceptions during the process of integration. It was also hoped that the research would help bring awareness and raise questions for future research and/or studies conducted on the same topic. The research design used was a mixed method qualitative ethnographic study. The key finding showed that the interviews established some themes. These themes were obtained by using thematic analysis. The most common positive themes were 1) factors helping immigrants, 2) educational programs & activities are beneficial, 3) managed to integrate by, and 4) immigration process. The most common negative themes were 1) credentials/work experience not accepted is the biggest challenge/hurdle, 2) religion, 3) health care not as good, 4) high cost of living, and 5) lack of Immigrants’ Experiences of Integrating into the Lower Mainland of BC vi information. Some minor themes also emerged which were 1) racism, 2) educational system, 3) other benefits and 4) other challenges. This research also helped the immigrants in sharing some of their own best solutions for improving the experiences of integration into communities in the Lower Mainland of British Columbia. Most of the information that appeared as a result of this research would also benefit any other future study or research. Immigrants’ Experiences of Integrating into the Lower Mainland of BC vii
Alpine Skiing With total knee ArthroPlasty (ASWAP): clinical and radiographic outcomes

The aim of the study was to assess the effect of a recreational alpine skiing intervention on implant‐related factors, such as loosening and wear, in patients with total knee arthoplasty (TKA). A group of 16 TKA patients were examined 2.3 ± 0.1 years after skiing about 80 days over three seasons inclusive of a ski intervention of 2–3 times per week (25.5 days) over a 12‐week period. Mean follow‐up period was 5.1 ± 1 years after surgery. All patients had excellent clinical and radiological outcomes. The average flexion was 120–130°, the average Oxford Knee Score increased from 15 points pre‐operatively to 47.4 points post‐operatively. An average Tegner activity level of 5.5 was assessed, indicating a very high post‐operative activity level. No radiolucencies or osteolyses were observed in any of the radiographs. One patient sustained a meniscal tear in the contralateral knee. Recreational alpine skiing on intermediate terrain at moderate speed can be recommended after TKA. Analysis of mid‐term follow‐up has not shown any negative effect on the implant loosening or additional polyethylene wear.
Action research for developing professional practice

The concept of practitioner- researcher was developed by Kurt Lewin in the 1940s as a research approach aimed at encouraging individuals to promote change and improve procedures through their own enquiry. This process is referred to as action research and is particularly appropriate in clinical settings where small-scale, problem-solving and evaluation enquiry can be effective in enhancing practice and developing professional autonomy.
Collaboratively filtering malware infections: a tensor decomposition approach

Malicious applications pose a threat to the security of the Android platform and Android smartphones often remain unprotected from novel malware. In this paper, we propose a Tensor filter, a collaborative approach for detection of Android malware, which extracting three feature sets into a three-order tensor A instead of a vector space. As the limited resources impede monitoring applications at run-time, Tensor filter performs a broad static analysis, gathering three contributed feature sets by a mathematical statistics method. These features are coded into a three-order tensor A and fitted an integrated tensor A* as well as deal with sparse problem by Tensor decomposition, which could reveal latent factors together. Tensor filter divides a large scale unknown applications into two categories, benign or malicious, according to integrated tensor A*, and typical combination of features indicative for malware can be used for explaining the decisions of our method. In an evaluation with 60,420 applications and 10,000 malware samples Tensor filter outperforms several industrial malware detection tools with the accuracy of 82.5%.
Photoproduction and Direct Spectral Detection of Singlet Molecular Oxygen ( 1 02) in Keratinocytes Stained with Rose Bengal

In vivo, keratinocyte skin cells are exposed to photoox‐idative processes, some of which can be mediated by singlet molecular oxygen (1O2), a species that is very difficult to detect spectrally in cells. We photosensitized 1O2 in cultured HaCaT keratinocytes stained with rose bengal (RB) that localizes exclusively inside the keratinocyte hydrophobic regions, as evidenced by strongly red‐shifted absorbance and intense fluorescence. We used keratinocytes grown in a monolayer on a plastic coverslip and in suspension. The phosphorescence spectrum (1200–1350nm) from 1O2 was strongest when the coverslip containing RB‐stained keratinocytes was irradiated in air. The spectral intensity decreased when the coverslip was immersed in D2O during irradiation and was almost completely quenched when it was irradiated while immersed in water. Water not only shortens the 1O2 lifetime but also reabsorbs part of the 1O2 phosphorescence, processes that do not occur when 1O2 is produced in a keratinocyte layer exposed to air. Because the RB was inside keratinocytes, singlet oxygen must also be produced inside the keratinocytes. However, the sensitivity to the extracellular environment suggests that most of the detectable 1O2 phosphorescence originates from those 1O2molecules that escaped from the cell through its membrane into D2O or into the air, where 1O2 has longer lifetimes. Our results confirm directly that 1O2 is indeed photosensitized in living cells by RB. They also suggest that keratinocyte monolayers may be a good cell model to examine in vitro the production of 1O2 by other photo‐sensitizers of environmental and photomedical interest.
Interpreting the Oil Risk Premium: Do Oil Price Shocks Matter?

This paper provides an analysis of the link between the global market for crude oil and oil futures risk premium at the aggregate level. It offers empirical evidence on whether the compensation for risk required by the speculators depends on the type of the structural shock of interest. Understanding the response of the risk premium to unexpected changes in the price of oil can be useful to address some research questions, among which: what is the relationship between crude oil risk premium and unexpected rise in the price of oil? On average, what should speculators expect to receive as a compensation for the risk they are taking on? This work is based on a Structural Vector Autoregressive (SVAR) model of the crude oil market. Two main results emerge. First, the impulse response analysis provides evidence of a negative relationship between the risk premium and the changes in the price of oil triggered by shocks to economic fundamentals. Second, this analysis shows that the historical decline of the risk premium can be modelled as a part of endogenous effect of the oil market driven shocks.
From Public Relations to Mob Rule: Media Framing of Social Licence in Canada

Background Social licence refers to the idea that corporations and governments require broad public support for resource development projects from affected communities, citizens, and stakeholders. Talk of social licence has become pervasive in media discussions of resource development in Canada and especially prominent in debates around oil pipelines. Analysis This article explores changing Canadian newspaper coverage of social licence over the past two decades. It identifies and analyzes the formation of four distinct “logics” of social licence: corporate, regulatory, oppositional, and conservative attack. Conclusions and implications This analysis provides a more robust framework for understanding how different groups have advanced competing visions of social licence within the public sphere, while illuminating the active role that news media have played in shaping the definition of social licence to fit their own editorial cultures. Contexte « Permis social » se rapporte a l’idee que les societes commerciales et les gouvernements requierent, pour le developpement des ressources, l’appui des communautes, citoyens et parties prenantes concernes. Cette idee de permis social apparait souvent dans les discours mediatiques sur le developpement energetique au Canada, surtout par rapport aux oleoducs. Analyse Cet article explore les changements dans la maniere dont les journaux canadiens ont traite du permis social au cours des deux dernieres decennies. Par rapport a ce concept, il identifie et analyse la formation de quatre « logiques » differentes : corporative, reglementaire, oppositionnelle et conservatrice attaquante. Conclusion et implications Cette analyse fournit un cadre plus robuste pour comprendre comment divers groupes ont mis l’accent dans la sphere publique sur des interpretations divergentes du permis social. D’autre part, elle elucide le role actif joue par les medias d’information dans la definition, selon leurs orientations editoriales, de ce qu’est le permis social.
How to measure snoring? A comparison of the microphone, cannula and piezoelectric sensor

The objective of this study was to compare to each other the methods currently recommended by the American Academy of Sleep Medicine (AASM) to measure snoring: an acoustic sensor, a piezoelectric sensor and a nasal pressure transducer (cannula). Ten subjects reporting habitual snoring were included in the study, performed at Landspitali—University Hospital, Iceland. Snoring was assessed by listening to the air medium microphone located on a patient's chest, compared to listening to two overhead air medium microphones (stereo) and manual scoring of a piezoelectric sensor and nasal cannula vibrations. The chest audio picked up the highest number of snore events of the different snore sensors. The sensitivity and positive predictive value of scoring snore events from the different sensors was compared to the chest audio: overhead audio (0.78, 0.98), cannula (0.55, 0.67) and piezoelectric sensor (0.78, 0.92), respectively. The chest audio was capable of detecting snore events with lower volume and higher fundamental frequency than the other sensors. The 200 Hz sampling rate of the cannula and piezoelectric sensor was one of their limitations for detecting snore events. The different snore sensors do not measure snore events in the same manner. This lack of consistency will affect future research on the clinical significance of snoring. Standardization of objective snore measurements is therefore needed. Based on this paper, snore measurements should be audio‐based and the use of the cannula as a snore sensor be discontinued, but the piezoelectric sensor could possibly be modified for improvement.
Transcription Profiling for Defensins of Aedes aegypti (Diptera: Culicidae) During Development and in Response to Infection With Chikungunya and Zika Viruses

Abstract Aedes aegypti (L.) is a vector of chikungunya, dengue, yellow fever and Zika viruses. These viruses encounter a variety of induced defense responses from the innate immune system of the mosquito. We cloned defensin A from Ae. aegypti using laboratory populations originating from Key West and Orlando, Florida. To characterize inducible immune defensin peptides, we examined the defensin A (DefA) and defensin C (DefC) expression through time course studies using quantitative real-time PCR. We observed that ingestion of chikungunya virus (CHIKV) and Zika virus (ZIKV) infected blood triggered early upregulated expression of DefA and DefC at 3 h after blood feeding. At 10-d post infection, there was significant downregulation of DefA and DefC in CHIKV-infected females and significant upregulation of DefA and DefC in ZIKV-infected females compared with control mosquitoes fed uninfected blood. Our studies demonstrate that the relative activity of DefA and DefC changed depending on whether Ae. aegypti was infected with CHIKV or ZIKV, suggesting differences in antiviral defense responses. In addition, we also examined DefA and DefC gene expression during the different developmental stages. Significant qualitative and quantitative differences were found in DefA and DefC transcripts between Key West and Orlando strains. We found that adult males consistently had higher expression than adult females of different ages. Together, these data show that members of the Ae. aegypti defensin gene family play a role in both Zika and chikungunya antiviral response.