Miracle-dz/UniFAR-FTUs huggingface dataset:
Improving the process variation tolerability of flip-flops for UDSM circuit design

The process variation of the ultra-deep submicron technology causes significant variation in the timing characteristics of flip-flops, and it can drop functional yield seriously, affecting system timing. This paper has two objectives. First, this paper investigates the sensitivities to process variation of four representative flip-flop architectures that are popularly used in digital circuit designs in respect of their functional robustness. Secondly, this paper proposes simple but effective methods to improve the process variation tolerability of those flip-flops. Experimental results on four benchmark flip-flops, which were optimized for minimum power-delay product, show that their variability of data-to-q delay reaches to 33.02% ∼ 46.13% and functional yield reaches to 79.93% ∼ 99.86%. Also, the experimental results clearly show that the proposed approaches improve the variability of data-to-q delay by 11.53% ∼ 44.78% and functional yield by 0.11% ∼ 24.41%.
MMIC circulators covering the frequency range from L- to W-band

A new type of circulators is presented which has been tested using circuits covering the frequency range from L- to W-band. This is, for the first time, a principle suitable for applications at 1.8 GHz as well as 77 GHz. At the lower frequencies ferrite drop-in circulators in microstrip technique have been used in the past, while at the upper frequencies the usage of circulators has not been established yet. The measurement result presented here demonstrate the applicability of the new concept.
Development of a Multiparent Population for Genetic Mapping and Allele Discovery in Six-Row Barley

Germplasm collections hold valuable allelic diversity for crop improvement and genetic mapping of complex traits. To gain access to the genetic diversity within the USDA National Small Grain Collection (NSGC), we developed the Barley Recombinant Inbred Diverse Germplasm Population (BRIDG6), a six-row spring barley multiparent population (MPP) with 88 cultivated accessions crossed to a common parent (Rasmusson). The parents were randomly selected from a core subset of the NSGC that represents the genetic diversity of landrace and breeding accessions. In total, we generated 6160 F5 recombinant inbred lines (RILs), with an average of 69 and a range of 37–168 RILs per family, that were genotyped with 7773 SNPs, with an average of 3889 SNPs segregating per family. We detected 23 quantitative trait loci (QTL) associated with flowering time with five QTL found coincident with previously described flowering time genes. A major QTL was detected near the flowering time gene, HvPpd-H1 which affects photoperiod. Haplotype-based analysis of HvPpd-H1 identified private alleles to families of Asian origin conferring both positive and negative effects, providing the first observation of flowering time-related alleles private to Asian accessions. We evaluated several subsampling strategies to determine the effect of sample size on the power of QTL detection, and found that, for flowering time in barley, a sample size >50 families or 3000 individuals results in the highest power for QTL detection. This MPP will be useful for uncovering large and small effect QTL for traits of interest, and identifying and utilizing valuable alleles from the NSGC for barley improvement.
A fusion algorithm of visual odometry based on feature-based method and direct method

A method that optimizes visual odometry, especially using visual odometry in the scene with absence of features is proposed in this paper. First, in order to estimate the pose of camera when the effect of using feature-based method is not good enough, direct method is implemented as the solution. Second, comparing with traditional visual odometry method, this method takes the environment restriction into consideration. On the one hand, if enough feature points are detected in a frame, feature-based method is to be used; on the other hand, direct method is used in the scene of missing features so that the accuracy of pose estimation could be guaranteed and improved. Finally, the feasibility of this method is proven by a number of experiments conducted on the experiment platform.
Power generation using tidal energy by artificial floating dam without turbine

Tidal energy is a form of hydropower that converts the energy of tides into electricity or other useful forms of power. It's also a renewable source of electricity which does not result in the emission of gases responsible for global warming or acid rain associated with fossil fuel generated electricity. Use of tidal energy could also decrease the need for nuclear power, with its associated radiation risks. The few studies that have been undertaken to date to identify the environmental impacts of a tidal power scheme have determined that each specific site is different and the impacts depend greatly upon local geography. If fossil fuel resources decline during the 21st century, as predicted by Hubbert peak theory, tidal power is one of the alternative sources of energy that will need to be developed to satisfy the human demand for energy. Whatever the process is a traditional power generation using a alternator and mechanical energy (for rotation) are collected from tidal energy using a simple floating device but create a artificial floating dam to hold huge energy, a system also involved to convert linier motion to rotary motion not using any traditional turbine.
AssociationofTelemedicineforRemoteMonitoring of Intensive Care Patients With Mortality , Complications , and Length of Stay

CARE PROVIDED IN INTENSIVE care units (ICUs) is notable for its high cost and high rates of morbidity and mortality. Because onsite staffing by intensivists has been associated with lower morbidity and mortality, experts recommend that intensivists care for ICU patients. However, there is a shortage of intensivists, which has led to the use of telemedicine technology to allow intensivists to remotely and simultaneously care for patients in several ICUs (ICU telemedicine [teleICU]), thus extending their reach. Remote monitoring may be a partial solution for the intensivist shortage, but it is expensive, its use is increasing, and there are few data in the peer-reviewed literature evaluating its effect on morbidity and mortality. Furthermore, it is not known whether remote monitoring by intensivists would benefit all or only a subset of ICU patients. Therefore, we conducted this study to assess the effect of a tele-ICU intervention on mortality, complications, and length of stay in 6 ICUs in a large health care system by measuring these outcomes before and after implementation of the tele-ICU. METHODS Setting We studied the use of a tele-ICU intervention in a large, nonprofit health care system located in the Gulf Coast region of the United States. The teleICU was implemented to care for all patients in 7 ICUs (one of these, a neurotrauma ICU, was not included in this study). When describing the ICUs, we use the term “closed” to indicate units in which intensivists were the only phy-
Differential carbohydrate binding and cell surface glycosylation of human cancer cell lines

Currently there is only a modest level knowledge of the glycosylation status of immortalised cell lines that are commonly used in cancer biology as well as their binding affinities to different glycan structures. Through use of glycan and lectin microarray technology, this study has endeavoured to define the different bindings of cell surface carbohydrate structures to glycan‐binding lectins. The screening of breast cancer MDA‐MB435 cells, cervical cancer HeLa cells and colon cancer Caco‐2, HCT116 and HCT116–FM6 cells was conducted to determine their differential bindings to a variety of glycan and lectin structures printed on the array slides. An inverse relationship between the number of glycan structures recognised and the variety of cell surface glycosylation was observed. Of the cell lines tested, it was found that four bound to sialylated structures in initial screening. Secondary screening in the presence of a neuraminidase inhibitor (4‐deoxy‐4‐guanidino‐Neu5Ac2en) significantly reduced sialic acid binding. The array technology has proven to be useful in determining the glycosylation signatures of various cell‐lines as well as their glycan binding preferences. The findings of this study provide the groundwork for further investigation into the numerous glycan–lectin interactions that are exhibited by immortalised cell lines. J. Cell. Biochem. 112: 2230–2240, 2011. © 2011 Wiley‐Liss, Inc.
Implication of Dopaminergic Systems on GnRH and GnRHR Genes Expression in the Hypothalamus and GnRH-R Gene Expression in the Anterior Pituitary Gland of Anestrous Ewes

We examined by Real-time PCR how prolonged inhibition of dopaminergic D-2 receptors (DA-2) in the hypothalamus of anestrous ewes by infusion of sulpiride into the third cerebral ventricle affected GnRH and GnRH-R gene expression in discrete parts of this structure and GnRH-R gene expression in the anterior pituitary. Blockaded DA-2 receptors significantly decreased GnRH mRNA levels in the ventromedial hypothalamus but did not evidently affect GnRH mRNA in the preoptic/ anteriorhypothalamicarea. Blockaded DA-2 receptors led to different responses in GnRH-R mRNA in various parts of the hypothalamus; increased GnRH-R mRNA levels in the preoptic/anterior hypothalamic area, and decreased GnRH-R mRNA amounts in the ventromedial hypothalamus stalk/median eminence. An infusion of sulpiride into the III-rd ventricle increased GnRH mRNA levels in the anterior pituitary gland and LH secretion. It is suggested that the increase of GnRH gene expression in the anterior pituitary gland and LH secretion in sulpiride-treated ewes are related with an increase of biosynthesis GnRH with concomitant decreased biosynthesis of GnRH-R protein in the ventromedial hypothalamus/stalk median eminence allowing to an increase of GnRH release.
Angiotensin II Receptor Blockade Inhibits Pneumocyte Apoptosis in Experimental Meconium Aspiration

Lung tissue inflammation and apoptosis are implicated in the pathogenesis of meconium aspiration–induced lung injury in the newborn, but the mechanisms of these reactions are still poorly known. We investigated the time-dependent leukocyte influx and appearance of apoptosis, as well as the contribution of angiotensin (ANG) II receptor action on these processes in the meconium-induced lung injury. Experimental meconium aspiration was induced by intratracheal instillation of human meconium in 18 rats, and eight rats were further pretreated with an unspecific ANG II receptor inhibitor saralasin. Rats were ventilated with 60% oxygen for 1, 3, or 5 h, and the lungs were then studied histologically for tissue injury and with DNA nick-end labeling and electron microscopy for apoptotic cell death. Lung tissue myeloperoxidase activity and expression of angiotensinogen mRNA and endothelial monocyte–activating polypeptide (EMAP) II protein were also analyzed. The meconium-instilled lungs showed increasing neutrophil migration and histologic injury after the first hour, whereas the number of epithelial apoptotic cells was elevated from the control level throughout the study. Myeloperoxidase activity was high, and the angiotensinogen mRNA and EMAP II protein was up-regulated at 5 h after the meconium insult. Pretreatment with saralasin significantly prevented the increase in lung tissue myeloperoxidase activity, EMAP II, and lung epithelial apoptosis. The results suggest that pulmonary meconium insult rapidly results in epithelial apoptosis, before significant neutrophil sequestration into the lungs. Apoptotic cell death is further connected with ANG II receptor action in the meconium-contaminated lung tissue.
Object Tracking with Shallow Convolution Feature

Traditional target tracking algorithm uses manual extraction of features, which is difficult to cope with the challenges of rotation and occlusion and deformation. Based on the deep learning method, the convolution neural network is used to extract the features. Because of lost a lot of spatial information in the convolution process, it's easy to make the tracking target drift. In this paper, we use a shallow convolutional network without second training to extract features for tracking, which combines hard negative mining technology and bounding box regression to refine the target location. We have compared our tracker performance with others state-of-the-art tracker. The obtained experimental results in OTB dataset demonstrate the effectiveness of our proposed tracker has outperformed the compared tracking algorithms.
Rechargeable Infection-responsive Antifungal Denture Materials

Candida-associated denture stomatitis (CADS) is a significant clinical concern. We developed rechargeable infection-responsive antifungal denture materials for potentially managing the disease. Polymethacrylic acid (PMAA) was covalently bound onto diurethane dimethacrylate denture resins in the curing step. The PMAA resins bound cationic antifungal drugs such as miconazole and chlorhexidine digluconate (CG) through ionic interactions. The anticandidal activities of the drug-containing PMAA-resin discs were sustained for a prolonged period of time (weeks and months). Drug release was much faster at acidic conditions (pH 5) than at pH 7. Drugs bound to the denture materials could be “washed out” by treatment with EDTA, and the drug-depleted resins could be recharged with the same or a different class of anticandidal drugs. These results suggest clinical potential of the newly developed antifungal denture materials in the management of CADS and other infectious conditions.
Quality-of-service provisioning to assured service in the wireless Internet

A major challenge in establishing the wireless Internet is provisioning of quality of service (QoS) to different Internet applications. In this paper, we propose a vertically layered scheme to provide QoS for the assured service with a committed information rate (CIR). By controlling the delay and packet loss performance seen from the transport layer, we can achieve the required CIR. Based on the proposed scheme, the resources needed to meet the rate requirement of the assured service can be determined. The resource allocation problem is also formulated as an optimization problem. Numerical results demonstrate that efficient resource utilization can be achieved.
REGULATING: THE SOCIAL CONTROL PROCESS REGISTERED NURSES USE TO TEACH PSYCHIATRIC PATIENTS ABOUT THEIR MEDICATIONS

In light of rising costs of health care, trends toward community based care, and greater demands by patients for control over their health, patient teaching has become a necessary part of the registered nurse's role. The purpose of this study was to describe how nurses teach patients with mental illness about their medication regimens. Twenty-nine nurses from three mental health settings in Australia participated in semistructured interviews and participant observation. The constant comparative method was used to analyze the data. Findings from this study indicated that the process of regulating, a social control process, was used by nurses to teach mentally ill patients about their medication regimens. Implications for practice and education are drawn from the findings of this study.
Correlation between polymorphism of vitamin D receptor TaqI and susceptibility to colorectal cancer

Abstract The meta-analysis aimed to investigate the correlation between the polymorphism of the vitamin D receptor (VDR) TaqI and susceptibility of colorectal cancer. Studies were extracted from the electronic databases of PubMed and Embase. The balance of heredity was estimated by the Hardy–Weinberg equilibrium test, and heterogeneity was assessed by Cochran Q statistics and I2 test. Four assessed models, namely additive (t vs T), dominant (Tt + tt vs TT), recessive (tt vs Tt + TT), and codominant (Tt vs TT and tt vs TT), were used to evaluate the correlations and the effective results were measured as odds ratio (OR) with 95% confidence interval (CI). A total of 14 studies, including 4632 patients and 5086 controls, were enrolled in this meta-analysis. With no significant heterogeneities observed among the 4 models, the fixed-effect model was used to examine the pooled effect value. There were no significant differences among t vs T (OR = 1.01; 95% CI, 0.94–1.09; P = .70), Tt + tt vs TT (OR = 1.05; 95% CI, 0.96–1.15; P = .32), tt vs Tt + TT (OR = 1.01; 95% CI, 0.87–1.17; P = .92), Tt vs TT (OR = 1.03; 95% CI, 0.93–1.13; P = .62), and tt vs TT (OR = 1.00; 95% CI, 0.85–1.17; P = .98) with respect to increasing CRC frequency. No evidence showed that TaqI polymorphisms were significantly associated with susceptibility to CRC.
Design and Implementation of Fast Transient Response Buck Converter with New Current-Mode Controlled Techniques

A new current-mode buck converter with current sensing and pulse width modulation (PWM) techniques is proposed. The improved-I2 controlled buck converter achieved a fast transient response and a wider bandwidth. The presented circuit with sensing control can reduce the number of the components. The buck converter provided the current load range within 50mA∼700mA. It has low output voltages and current ripples. The buck converter has been designed and implemented with TSMC 0. 35μm CMOS 2P4M technology. The maximum power efficiency is 90.8%. The area of the whole chip is 1.5mm × 1.5mm.
Molecular and structural basis of glutathione import in Gram‐positive bacteria via GshT and the cystine ABC importer TcyBC of Streptococcus mutans

Glutathione (GSH) protects cells against oxidative injury and maintains a range of vital functions across all branches of life. Despite recent advances in our understanding of the transport mechanisms responsible for maintaining the spatiotemporal homeostasis of GSH and its conjugates in eukaryotes and Gram‐negative bacteria, the molecular and structural basis of GSH import into Gram‐positive bacteria has remained largely uncharacterized. Here, we employ genetic, biochemical and structural studies to investigate a possible glutathione import axis in Streptococcus mutans, an organism that has hitherto served as a model system. We show that GshT, a type 3 solute binding protein, displays physiologically relevant affinity for GSH and glutathione disulfide (GSSG). The crystal structure of GshT in complex with GSSG reveals a collapsed structure whereby the GS‐I‐leg of GSSG is accommodated tightly via extensive interactions contributed by the N‐ and C‐terminal lobes of GshT, while the GS‐II leg extends to the solvent. This can explain the ligand promiscuity of GshT in terms of binding glutathione analogues with substitutions at the cysteine‐sulfur or the glycine‐carboxylate. Finally, we show that GshT primes glutathione import via the l‐cystine ABC transporter TcyBC, a membrane permease, which had previously exclusively been associated with the transport of l‐cystine.
Subband coding of audio signal with logarithmic compandors

This paper presents an audio compression system that applies the sub-band coding (SBC) technique with logarithmic compandors. SBC decomposes signal into the chosen number of frequency bands, which are coded separately. The goal is to design a SBC system that uses quasi-logarithmic quantizers and to find the optimal bit allocation. This would result in decrease of the average number of bits required and provide the gain in signal to quantization noise ratio (SQNR), compared to the pulse-code modulation (PCM) system.
Comparison of very small businesses of Arabs and Jews in the North Israel periphery

Very small businesses owned by Arabs and Jews in the north of Israel are compared and discussed along several dimensions: education and experience of the entrepreneurs, field and location of businesses, business success, formal and informal support of businesses, and strengths and weaknesses of the businesses. The main finding of the study is the contrasting tendencies of small businesses in the Arab and Jewish sectors: the majority of Arab entrepreneurs reported a decrease in profit while most Jews pointed to a profit increase. We relate this to differences in the structure of the business fields that in turn depend on targeted market segments and product characteristics.
Evaluation of Antimicrobial Activities of Several Mannich Bases and Their Derivatives

The aim of this study was to evaluate the antimicrobial activities of several Mannich bases and their derivatives against pathogenic bacteria and fungi. 3‐Dimethylamino‐1‐phenyl‐1‐propanone hydrochloride (Ig1) as mono‐Mannich base, bis(β‐aroylethyl)methylamine hydrochlorides (B1, B5) as bis‐Mannich bases, 3‐aroyl‐4‐aryl‐1‐methyl‐4‐piperidinol hydrochlorides (C1, C5) as piperidinol derivatives, which are structural isomers of bis‐Mannich bases, N,N'‐Bis(3‐dimethylamino‐1‐phenylpropylidene)hydra zine dihydrochlorides (D1) as azine derivative of mono‐Mannich base Ig1, and some representative quaternary derivatives (Ig4 and C6), which are quaternary derivatives of Ig1 and C1, respectively, have been synthesized. Aryl parts were phenyl in B1 and C1, and 2‐thienyl in B5 and C5. Bis‐Mannich bases and quaternary Mannich bases were found to be effective antifungal derivatives. Quaternary mono‐Mannich base Ig4 has shown twice the amount of higher antifungal potency against the human pathogenic fungus Microsporum canis compared with the reference drug amphotericin‐B and it had equal potency against many other fungi species pathogenic in humans and plants. Ig4 was effective against Staphylococcus aureus among the bacteria tested. Preparation of bis‐Mannich bases and qua ternization procedure seemed suitable chemical modifications to prepare effective antifungal compounds. Especially quaternary derivatives Ig4, and to some extent C6, seem to be model compounds to develop new antimicrobial agents for further studies.
Instant messaging adoption in China: implications for young entrepreneurs

Instant messaging (IM) is a popular internet application. In China, there are more than ten IM products competing with each other. Of them, Tencent’s QQ owned and managed by a young Chinese entrepreneur is in a dominant position taking about 90% of the market share. This paper identifies the factors that determine the wide adoption of QQ by students and staffs in a Chinese university, which are social influence, enjoyment and communications effectiveness associated with this IM. Practical implications for young entrepreneurs as the main forces of IM business are offered.
The Level Of Knowledge In The Value Relevance Literature

In the last decades, numerous studies have covered the relationship between stock price or stock return and financial information. These studies represent the "value-relevance" literature. Knowledge of this area of interest, through literature and the main ideas, yields scientific progress. The aim of the study is to achieve a qualitative and a quantitative analysis regarding the level of knowledge in the value relevance literature, in an international context. To achieve this aim, a number of 53 scientific articles published between 2001 and 2013 were selected, from the first two journals related to the number of citations in the rankings compiled by Google Scholar, Accounting and Taxation category. Qualitative analysis and quantitative analysis (factorial analysis of multiple correspondences as statistical method) were used. The results reflect the importance of existing problems in the financial markets. The studies are focused on solving these problems, to support the investors.