Miracle-dz/UniFAR-FTUs huggingface dataset:
La cooperativa de trabajo asociado de trabajadores y el sentimiento de pertenencia de su profesorado

En la cooperativa de trabajo asociado la titularidad corresponde a sus trabajadores y en esta investigacion se analiza el sentimiento de pertenencia de sus profesores. El sentimiento de pertenencia responde al componente emocional de la implicacion, la identificacion con el centro escolar. La muestra esta compuesta por 36 de los 72 profesores de la unica cooperativa de este tipo en la provincia de Alava. Se ha utilizado el cuestionario « Phycological Sense of School Membership » (PSSM) de Goodenow (1993) todavia no utilizado en nuestro pais y se ha creado un cuestionario especifico para el profesorado inedito a nivel mundial. Los resultados sugieren que el sentimiento de pertenencia es mas elevado en los hombres, en los que trabajan en los niveles de primaria, en los tutores y en los que tienen familiares en el centro. Estudiar los factores que afectan al sentimiento de pertenencia de los profesores es clave para evitar las altas tasas de abandono y fracaso escolar de los estudiantes.
Angiotensin II receptors in Xenopus oocytes

Electrical recordings were used to study the sensitivity of native Xenopus oocytes to the octapeptide angiotensin II (All). All elicited oscillatory currents associated with an increase in membrane conductance to Cl-. Responsiveness to All varied greatly between oocytes taken from different frogs, and to a lesser extent between oocytes from the same ovary. Oocytes from frogs showing high sensitivity had response thresholds between 0.5-1.0 nM All, and at a holding potential of – 60 mV, responded to 1 μm All with currents greater than 3 μA. In contrast, oocytes from some frogs gave no response, even to 10 μm All. A total of 618 oocytes from 79 frogs were tested for sensitivity to All, and oocytes from 85% of frogs gave detectable electrical responses. Oscillatory Cl- currents elicited by All were largely independent of extracellular Ca2+, were abolished by chelation of intracellular Ca2+ using EGTA and were mimicked by intraoocyte injection of inositol 1, 4, 5 - trisphosphate (IP3). In addition to oscillatory Cl- currents, All also evoked an influx of extracellular Ca2+, giving rise to a transient inward Cl- current on membrane hyperpolarizing steps. These experiments all suggested that All responses were elicited through activation of an intracellular messenger pathway triggered by hydrolysis of inositolphospholipids, mobilization of intracellular Ca2+ by inositol polyphosphates, and activation of Ca2+ - gated Cl- channels. The effect of manual or enzymic defolliculation on All responses was studied in nine separate experiments recording from 70 defolliculated oocytes. Efficacy of defolliculation procedures was assayed using scanning electron microscopy, which confirmed removal of 90 to greater than 98% of follicular cells. In all cases All responses were substantially preserved through defolliculation, suggesting that the All receptors that mediate membrane current responses are located in the oocyte itself, and not in follicular cells.
Non-Mendelian, heritable blocks to DNA rearrangement are induced by loading the somatic nucleus of Tetrahymena thermophila with germ line-limited DNA

Site-specific DNA deletion occurs at thousands of sites within the genome during macronuclear development of Tetrahymena thermophila. These deletion elements are usually not detected in macronuclear chromosomes. We have interfered with the normal deletion of two of these elements, the adjacent M and R elements, by loading vegetative macronuclei with these elements prior to sexual conjugation. Transformed cell lines containing the exogenous M or R element, carried on high-copy-number vectors containing genes encoding rRNA within parental (old) macronuclei, consistently failed to excise chromosomal copies of the M or R element during formation of new macronuclei. Little or no interference with the deletions of adjacent elements or of unlinked elements was observed. The micronucleus (germ line)-limited region of each element was sufficient to inhibit specific DNA deletion. This interference with DNA deletion usually is manifested as a cytoplasmic dominant trait: deletion elements present in the old macronucleus of one partner of a mating pair were sufficient to inhibit deletion occurring in the other partner. Remarkably, the failure to excise these elements became a non-Mendelian, inheritable trait in the next generation and did not require the high copy number of exogenously introduced elements. The introduction of exogenous deletion elements into parental macronuclei provides us with an epigenetic means to establish a heritable pattern of DNA rearrangement.
Spectral-Spatial Classification Integrating Band Selection for Hyperspectral Imagery With Severe Noise Bands

Spectral-spatial classification for hyperspectral imagery has been receiving much attention, since the detailed spectral and rich spatial information of hyperspectral images can be fully exploited to improve the classification accuracy. However, when the original hyperspectral images have very noisy bands, these bands may have an unfavorable impact on the classification, and are often discarded in advance based on expert knowledge. In this study, a spectral-spatial conditional random field classification algorithm integrating band selection (CRFBS) is developed for hyperspectral imagery with severe noise bands. The proposed algorithm integrates band selection based on the relative utility of the spectral bands for classification. Consequently, negative effects of severe noise bands are eliminated and the need for high-quality image data is substantially reduced. In addition, the CRFBS algorithm makes comprehensive use of both the spectral and the spatial cues to improve the classification performance. The spectral cues are formulated by integrating the support vector machine and random forest algorithms to improve the spectral discriminative ability in the unary potentials, and the spatial information are modeled to consider the interactions between pixels in pairwise potentials. The experiments using different airborne and UAV-borne hyperspectral data verified the effectiveness of the CRFBS method. The CRFBS algorithm can achieve accurate interpretation of the various classification categories and a more than 3% improvement in classification accuracy, compared with the method using the original hyperspectral image with severe noise bands.
The Energy Envelope Theory and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Individuals with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) have little stamina and endurance, and pose a challenge for nursing professionals. The Energy Envelope Theory, which posits that maintaining expended energy levels consistent with available energy levels may reduce the frequency and severity of symptoms, is particularly useful when working with clients with ME/CFS. Anecdotal support from the client community for this theory supports its use as a management tool for ME/CFS, but little formal research has been done in this area. In this study, a daily energy quotient was established by dividing the expended energy level by the perceived energy level and multiplying by 100. It was predicted that those participants who expended energy beyond their level of perceived energy would have more severe fatigue and symptoms and lower levels of physical and mental functioning. Findings are congruent with the Energy Envelope Theory as they indicated that the daily energy quotient was related to several indices of functioning including depression, anxiety, fatigue, pain, quality of life, and disability. The overall results provide support for a strategy health care professionals can use when working with clients with ME/CFS.
A Critical Examination of Escherichia coli Esterase Activity*

The ability of Escherichia coli to grow on a series of acetylated and glycosylated compounds has been investigated. It is surmised that E. coli maintains low levels of nonspecific esterase activity. This observation may have ramifications for previous reports that relied on nonspecific esterases from E. coli to genetically encode nonnatural amino acids. It had been reported that nonspecific esterases from E. coli deacetylate tri-acetyl O-linked glycosylated serine and threonine in vivo. The glycosylated amino acids were reported to have been genetically encoded into proteins in response to the amber stop codon. However, it is our contention that such amino acids are not utilized in this manner within E. coli. The current results report in vitro analysis of the original enzyme and an in vivo analysis of a glycosylated amino acid. It is concluded that the amber suppression method with nonnatural amino acids may require a caveat for use in certain instances.
Determination of the Optimum Guard Interval for an MC-CDMA system using measurement-based channel models

Frequency selective channel distortions in the Multi Carrier Code Division Multiple Access (MC-CDMA) system is reduced with the use of guard interval. In previous works, guard interval is associated with root mean square delay spread of the channel (τrms) and the symbol duration. This paper investigates the sensitivity of MC-CDMA performance to guard interval and demonstrates a novel approach to determine the Optimum Guard Interval (OGI). System performance is determined from the Signal to Noise Ratio (SNR) level of a detected bit. The OGI for a given channel profile and system parameters is determined as the guard interval with maximum SNR. Unlike the previous studies, the OGI was investigated for different Es/N0. The OGI are growing increasingly with Es/N0 and is equal to maximum delay spread for Es/N0=30dB. We show that the OGI used depending on Es/N0 can be selected as the delay window that includes certain multipath power. With such a method with different frequency selective channel profile the optimum guard interval without the need for complex operations can be identified.
A High-performance Web Attack Detection Method based on CNN-GRU Model

WEB attack detection is an important part of WEB security. This paper proposes a web attack detection method based on Convolutional Neural Network (CNN) combined with Gated Recurrent Unit (GRU). In order to improve the detection performance, we extract eight statistical features with good classification effect to augment the original data. In addition, we also pre-trained the word embedding matrix using the word2Vec model, then obtained the input of the CNN-GRU model and classified the final results. The experimental results show that the accuracy of the method in the HTTP CSIC 2010 dataset is 99.00%, the recall rate is 97.74%, the F1 value is 98.77% and the precision is 99.82%. Compared with traditional machine learning methods, this method proposed in this paper has better performance.
Olfactory impairments in child attention-deficit/hyperactivity disorder.

OBJECTIVE This study compared unilateral olfactory identification abilities in children with and without attention-deficit/hyperactivity disorder (ADHD) and evaluated the utility of the University of Pennsylvania Smell Identification Test (UPSIT) as a potential screening tool for the diagnosis of ADHD. METHOD Subjects comprised 44 children with DSM-IV ADHD (aged 7-16 years) from 2 Melbourne, Australia, hospital outpatient clinics and 44 healthy children matched for age and sex. The children were assessed from March 2004 to October 2004 for olfactory identification ability using the UPSIT, and behavioral data were gathered using the Rowe Behavioral Rating Inventory. Background and demographic data were also obtained through hospital records and parental interview. RESULTS Children with ADHD demonstrated significantly poorer olfactory identification ability compared to healthy controls (p < .01). A significant right nostril advantage for smell identification was evident in the control group (p < .01), whereas significant right nostril impairment was evident among the children with ADHD (p < .01). CONCLUSION The results provide the first evidence of olfactory identification deficits in children with ADHD. As such deficits implicate orbitofrontal regions, this finding is consistent with previous reports of prefrontal compromise in children with ADHD.
Exchange of Xcp (Gsp) Secretion Machineries betweenPseudomonas aeruginosa and Pseudomonas alcaligenes: Species Specificity Unrelated to Substrate Recognition

ABSTRACT Pseudomonas aeruginosa and Pseudomonas alcaligenes are gram-negative bacteria that secrete proteins using the type II or general secretory pathway, which requires at least 12 xcp gene products (XcpA and XcpP to -Z). Despite strong conservation of this secretion pathway, gram-negative bacteria usually cannot secrete exoproteins from other species. Based on results obtained with Erwinia, it has been proposed that the XcpP and/or XcpQ homologs determine this secretion specificity (M. Linderberg, G. P. Salmond, and A. Collmer, Mol. Microbiol. 20:175–190, 1996). In the present study, we report that XcpP and XcpQ of P. alcaligenes could not substitute for their respectiveP. aeruginosa counterparts. However, these complementation failures could not be correlated to species-specific recognition of exoproteins, since these bacteria could secrete exoproteins of each other. Moreover, when P. alcaligenes xcpP andxcpQ were expressed simultaneously in a P. aeruginosa xcpPQ deletion mutant, complementation was observed, albeit only on agar plates and not in liquid cultures. After growth in liquid culture the heat-stable P. alcaligenes XcpQ multimers were not detected, whereas monomers were clearly visible. Together, our results indicate that the assembly of a functional Xcp machinery requires species-specific interactions between XcpP and XcpQ and between XcpP or XcpQ and another, as yet uncharacterized component(s).
Automatic Power Emergency Dispatching System based on Voice Response

In recent years, there have been many blackouts in the world, which have a serious impact on social and economic development. Therefore, it has become an extremely important topic to study power emergency dispatching technology and reduce the loss caused by power emergency. In case of a large power accident, the data communication may be abnormal, and sensors may fail completely. At this time, dispatchers and field staff can only exchange accident information in the form of voice by telephones or mobile phones, and various instructions can only be issued in the form of voice. Even if we set up an automatic power emergency dispatching system, these voice messages and instructions can only be manually input while listening. It is slow in response and prone to errors, especially requiring a keyboard, which is inconvenient for field staff. For this reason, this paper presents to add a speech recognition module into the automatic power emergency dispatching system. At the same time, a semantic understanding module is trained by the knowledge base of the emergency decision system. Semantic understanding further improves the accuracy of speech recognition. The text after speech recognition is sorted into a standard format and input into a emergency decision-making system to get more accurate results, which are sent to field staff by voice.
Human NELL1 Protein Augments Constructive Tissue Remodeling with Biologic Scaffolds

Biologic scaffolds composed of extracellular matrix (ECM) derived from decellularized tissues effectively reprogram key stages of the mammalian response to injury, altering the wound microenvironment from one that promotes scar tissue formation to one that stimulates constructive and functional tissue remodeling. In contrast, engineered scaffolds, composed of purified ECM components such as collagen, lack the complex ultrastructure and composition of intact ECM and may promote wound healing but lack factors that facilitate constructive and functional tissue remodeling. The objective of the present study was to test the hypothesis that addition of NELL1, a signaling protein that controls cell growth and differentiation, enhances the constructive tissue remodeling of a purified collagen scaffold. An abdominal wall defect model in the rat of 1.5-cm2 partial thickness was used to compare the constructive remodeling of a bovine type I collagen scaffold to a biologic scaffold derived from small intestinal submucosa (SIS)-ECM with and without augmentation with 17 μg NELL1 protein. Samples were evaluated histologically at 14 days and 4 months. The contractile response of the defect site was also evaluated at 4 months. Addition of NELL1 protein improved the constructive remodeling of collagen scaffolds but not SIS-ECM scaffolds. Results showed an increase in the contractile force of the remodeled skeletal muscle and a fast:slow muscle composition similar to native tissue in the collagen-treated group. The already robust remodeling response to SIS-ECM was not enhanced by NELL1 at the dose tested. These findings suggest that NELL1 protein does contribute to the enhanced constructive remodeling of skeletal muscle.
Observation of capillary flow in human skin during tissue compression using CCD video-microscopy

Recent technological advances of the CCD video-camera have made microscopes more compact and greatly improved their sensitivity. We newly designed a compact capillaroscopy which was composed with a CCD video-probe equipped a contact-type objective lens and illuminator. In the present study, we evaluated usefulness of the instrument for a bed-side human capillaroscopy to observe the capillary flow in various dermal regions. The influences of tissue compression on the dermal capillary blood flow were also investigated to confirm the utility for clinical applications. Our capillaroscopy visualized the nutritional capillary blood flow in almost all parts of skin surface. Our observations showed that a level of vertical stress similar to arterial pressure was required to stop the capillary flow. From these demonstrations the present CCD video-probe based capillaroscopy would be useful for clinical applications as a bed-side human capillaroscopy.
School-Level Practices to Increase Availability of Fruits, Vegetables, and Whole Grains, and Reduce Sodium in School Meals - United States, 2000, 2006, and 2014.

Students consume up to half of their daily calories at school, often through the federal school meal programs (e.g., National School Lunch Program) administered by the U.S. Department of Agriculture (USDA). In 2012, USDA published new required nutrition standards for school meals. * These standards were the first major revision to the school meal programs in >15 years and reflect current national dietary guidance and Institute of Medicine recommendations to meet students' nutrition needs. The standards require serving more fruits, vegetables, and whole grains and gradually reducing sodium content over 10 years. To examine the prevalence of school-level practices related to implementation of the nutrition standards, CDC analyzed data from the 2000, 2006, and 2014 School Health Policies and Practices Study (SHPPS) on school nutrition services practices related to fruits, vegetables, whole grains, and sodium. Almost all schools offered whole grain foods each day for breakfast and lunch, and most offered two or more vegetables and two or more fruits each day for lunch. The percentage of schools implementing practices to increase availability of fruits and vegetables and decrease sodium content in school meals increased from 2000-2014. However, opportunities exist to increase the percentage of schools nationwide implementing these practices.
Vascularisation of tissue-engineered grafts: the regulation of angiogenesis in reconstructive surgery and in disease states.

Angiogenesis (the formation of new blood vessels) is essential for the growth of new tissue, tissue repair and wound healing. Tissue engineering, the construction of new tissue and organs for reparative purposes, relies on angiogenesis for the vascularisation of these new grafts. In tissue engineering, the emphasis to date has been on vascularisation of newly constructed tissue grafts by an extrinsic blood supply, and relatively little attention has been given to the possibility of building these grafts around an intrinsic blood supply. However, there are many disease processes, notably tumour growth, where excess angiogenesis can be a major problem. The purposes of this review are, first, to examine various methods of vascularising tissue-engineered grafts, and, second, to compare the role of angiogenesis in tissue engineering, where stimulation of angiogenesis is paramount, with pathological states, such as tumour growth, where angiogenesis needs to be inhibited.
The Two Major Human Metapneumovirus Genetic Lineages Are Highly Related Antigenically, and the Fusion (F) Protein Is a Major Contributor to This Antigenic Relatedness

ABSTRACT The growth properties and antigenic relatedness of the CAN98-75 (CAN75) and the CAN97-83 (CAN83) human metapneumovirus (HMPV) strains, which represent the two distinct HMPV genetic lineages and exhibit 5 and 63% amino acid divergence in the fusion (F) and attachment (G) proteins, respectively, were investigated in vitro and in rodents and nonhuman primates. Both strains replicated to high titers (≥6.0 log10) in the upper respiratory tract of hamsters and to moderate titers (≥3.6 log10) in the lower respiratory tract. The two lineages exhibited 48% antigenic relatedness based on reciprocal cross-neutralization assay with postinfection hamster sera, and infection with each strain provided a high level of resistance to reinfection with the homologous or heterologous strain. Hamsters immunized with a recombinant human parainfluenza virus type 1 expressing the fusion F protein of the CAN83 strain developed a serum antibody response that efficiently neutralized virus from both lineages and were protected from challenge with either HMPV strain. This result indicates that the HMPV F protein is a major antigenic determinant that mediates extensive cross-lineage neutralization and protection. Both HMPV strains replicated to low titers in the upper and lower respiratory tracts of rhesus macaques but induced high levels of HMPV-neutralizing antibodies in serum effective against both lineages. The level of HMPV replication in chimpanzees was moderately higher, and infected animals developed mild colds. HMPV replicated the most efficiently in the respiratory tracts of African green monkeys, and the infected animals developed a high level of HMPV serum-neutralizing antibodies (1:500 to 1:1,000) effective against both lineages. Reciprocal cross-neutralization assays in which postinfection sera from all three primate species were used indicated that CAN75 and CAN83 are 64 to 99% related antigenically. HMPV-infected chimpanzees and African green monkeys were highly protected from challenge with the heterologous HMPV strain. Taken together, the results from hamsters and nonhuman primates support the conclusion that the two HMPV genetic lineages are highly related antigenically and are not distinct antigenic subtypes or subgroups as defined by reciprocal cross-neutralization in vitro.