Miracle-dz/UniFAR-FTUs huggingface dataset:
Estimating Camera Pose Using Trajectories Generated by Pan-Tilt Motion

A novel method for auto-calibration of a PTZ (pan-tilt-zoom) camera network is proposed. The key idea on which it is based is to use pan-tilt motions generated by PTZ cameras themselves as calibration patterns. Generating and observing the pan-tilt motions of each camera makes it possible to estimate whole relative camera poses in a camera network. Cameras first observe circular trajectories of a marker set on another camera performing tilt motions with various pan angles. Although finding correspondences between marker points captured by the cameras is cumbersome due to network delays, that of between circular trajectories is easy. It is thus possible to use several hundred points in a circular trajectory to estimate its normal vectors and centers with high accuracy. Imposing geometric constraints on them makes it possible to eliminate ambiguities of them and obtain a unique relative camera pose directly. A novel refinement process to minimize differences between modeled pan-tilt motions and three or more circular trajectories is then performed. Experiments using synthetic data confirmed that the refinement process improved camera pose estimation accuracy in comparison to the direct estimation. An experiment using real data showed that the proposed method works properly for real cameras.
A 4-Path 42.8-to-49.5 GHz LO Generation With Automatic Phase Tuning for 60 GHz Phased-Array Receivers

This paper presents a 4-path LO generation system with automatic phase tuning for 60 GHz phased-array receivers. Each path employs a linear phase-shift generation chain composed of an injection-locked-oscillator-based phase shifter cascaded with an injection-locked frequency tripler. The frequency tripler with a proposed locking-range enhancement technique is employed to relax both the frequency and the phase shift of the phase shifter for high linearity and low power. Finally, a novel successive-approximation algorithm is proposed to perform automatic phase detection and tuning. Fabricated in a 65 nm CMOS process and occupying a core area of 1.4 ×2.0 mm2, the proposed 4-path LO generation system measures linear phase shift range larger than ±90°, amplitude variation within ±0.4 dB, phase resolution of 22.5°, and maximum phase errors of 22.0° and 1.5° before and after automatic phase calibration while drawing a current of 85 mA from a 1-V supply.
Supratherapeutic dosing of acetaminophen among hospitalized patients.

BACKGROUND We investigated acetaminophen use and identify factors contributing to supratherapeutic dosing of acetaminophen in hospitalized patients. METHODS We retrospectively reviewed the electronic health records of adult patients who were admitted to 2 academic tertiary care hospitals (hospital A amd hospital B) from June 1, 2010, to August 31, 2010, and who received acetaminophen during their hospitalization. Patients' acetaminophen administration records (including drug name, dose, administration time, hospital units, etc), demographic data, diagnoses, and results from liver function tests were obtained. The main outcome measures included acetaminophen exposure rate and supratherapeutic dosing rate among hospitalized patients, hazard ratios (HRs) and 95% confidence intervals (CIs) for risk factors for supratherapeutic dosing, and changes in liver function test before and after supratherapeutic dosing. RESULTS A total of 14 411 patients (60.7%) were exposed to acetaminophen, of whom 955 (6.6%) exceeded the 4 g per day maximum recommended dose. In addition, 22.3% of patients who were 65 years or older and 17.6% of patients with chronic liver diseases exceeded the recommended limit of 3 g per day. Patients receiving excessive doses of acetaminophen tended to have significant alkaline phosphatase elevations, although causal relationship cannot be concluded. A significantly higher risk of supratherapeutic dosing was observed in hospital A (HR, 1.6 [95% CI, 1.4-1.8]), white patients (HR, 1.5 [95% CI, 1.3-1.7]), patients diagnosed as having osteoarthritis (HR, 1.4 [95% CI, 1.3-1.6]), and those who received scheduled administrations (HR, 16.6 [95% CI, 13.5-20.6]), multiple product formulations (HR, 2.4 [95% CI 2.0-2.9]), or the 500-mg strength formulation (HR, 1.9 [95% CI, 1.5-2.3]). A lower risk was found for pro re nata (as needed) administrations (HR, 0.7 [95% CI, 0.6-0.9]) and in nonsurgical and non–intensive care units (HR, 0.6 [95% CI, 0.5-0.7]). CONCLUSIONS Supratherapeutic dosing of acetaminophen was significantly associated with multiple factors. Interventions to reduce the incidence of some risk factors may prevent supratherapeutic acetaminophen dosing in hospitalized patients.
Regent-Dependent Creativity: A Domain Independent Metric for the Assessment of Creative Artifacts

Humans are the ultimate judges on how creative is an artifact. In order to be creative, most researchers agree that an artifact has to be at least new and valuable. How- ever, metrics to evaluate novelty and value are often craft for individual studies. Even within the same do- main, these metrics commonly differ. Although this variety of metrics extends the spectrum of alternatives to assess creative artifacts, the lack of domain independent metrics makes hard to compare artifacts produced by different studies, which in turn slows down the research progress in the ﬁeld. In this paper, we propose an domain independent metric, called Regent-Dependent Creativity (RDC), that assesses the creativity of arti- facts. This metric requires that artifacts are described within the Regent-Dependent Model, in which artifacts features are represented as dependency pairs. RDC combines the Bayesian Surprise and Synergy to mea- sure novelty and value, respectively. We show two case studies from different domains (fashion and games) to demonstrate how to model artifacts and assess creativity through RDC. We also propose and make available a simple API to promptly use RDC.
Quartz-Indium Tin Oxide-Magnesium Flouride Sandwich in a Low Density Plasma

Indium tin oxide (ITO) coatings of solar cell coverglasses have been used for a long time to prevent electrostatic discharges on the array surface of a spacecraft in geosynchronous orbit. An antireflection layer of magnesium fluoride is also a common feature of solar cell design that allows increasing array efficiency by a few percent. Currently, some spacecraft in geosynchronous orbit have solar arrays with ITO-MgF2 coatings, and their power systems have experienced significant degradations. Analysis of telemetric data from these satellites shows strong correlations between the events of the sudden power losses and station keeping thruster firing time intervals. The main features of this solar array behavior in an arc jet plume plasma have been reproduced in an experiment in a plasma chamber
Preprocessing in a reaction-diffusion algorithm designed for image edge detection

This paper proposes a reaction-diffusion algorithm for image edge detection in the framework of FitzHugh-Nagumo model. FitzHugh-Nagumo model has two variables, activator and inhibitor, which are governed by two timeevolving differential equations, respectively, for simulating a process of biological excitation and inhibition phenomenon observed along a nerve. The proposed algorithm places FitzHugh-Nagumo elements, which contains a pair of activator and inhibitor variables, at the image grids. At first, the algorithm gives initial conditions of the elements according to an inputted gray level image. Then, it performs preprocessing for reducing noise by using only inhibition equation at the elements, and finally performs edge-detection by using both excitation and inhibition equations. The performance of the proposed algorithm is investigated with artificial and real images.
Geographical distribution of soil transmitted helminths and the effects of community type in South Asia and South East Asia – A systematic review

Background Soil-transmitted helminth (STH) infections are among the most prevalent neglected tropical diseases (NTD) worldwide. Since the publication of the WHO road map to combat NTD in 2012, there has been a renewed commitment to control STH. In this study, we analysed the geographical distribution and effect of community type on prevalence of hookworm, Trichuris and Ascaris in south Asia and south east Asia. Methodology We conducted a systematic review of open-access literature published in PubMed Central and the Global Atlas of Helminth Infection. A total of 4182 articles were available and after applying selection criteria, 174 studies from the region were retained for analysis. Principal findings Ascaris was the commonest STH identified with an overall prevalence of 18% (95% CI, 14–23%) followed by Trichuris (14%, 9–19%) and hookworm (12%, 9–15%). Hookworm prevalence was highest in Laos, Vietnam and Cambodia. We found a geographical overlap in countries with high prevalence rates for Trichuris and Ascaris (Malaysia, Philippines, Myanmar, Vietnam and Bangladesh). When the effect of community type was examined, prevalence rates of hookworm was comparable in rural (19%, 14–24%) and tribal communities (14%, 10–19%). Tribal communities, however, showed higher prevalence of Trichuris (38%, 18–63%) and Ascaris (32%, 23–43%) than rural communities (13%, 9–20% and 14%, 9–20% respectively). Considerable between and within country heterogeneity in the distribution of STH (I2 >90%) was also noted. When available data from school aged children (SAC) were analysed, prevalence of Ascaris (25% 16–31%) and Trichuris (22%, 14–34%) were higher than among the general population while that of hookworm (10%, 7–16%) was comparable. Conclusions/Significance Our analysis showed significant variation in prevalence rates between and within countries in the region. Highlighting the importance of community type in prevalence and species mix, we showed that tribal and rural communities had higher hookworm infections than urban communities and for ascariasis and trichuriasis, tribal populations had higher levels of infection than rural populations. We also found a higher prevalence of ascariasis and trichuriasis in SAC compared to the general population but comparable levels of hookworm infections. These key findings need to be taken into account in planning future MDA and other interventions.
A robust adaptive observer for a class of singular nonlinear uncertain systems

ABSTRACT This paper proposes a robust adaptive observer for a class of singular nonlinear non-autonomous uncertain systems with unstructured unknown system and derivative matrices, and unknown bounded nonlinearities. Unlike many existing observers, no strong assumption such as Lipschitz condition is imposed on the recommended system. An augmented system is constructed, and the unknown bounds are calculated online using adaptive bounding technique. Considering the continuous nonlinear gain removes the chattering which may appear in practical applications such as analysis of electrical circuits and estimation of interaction force in beating heart robotic-assisted surgery. Moreover, a simple yet precise structure is attained which is easy to implement in many systems with significant uncertainties. The existence conditions of the standard form observer are obtained in terms of linear matrix inequality and the constrained generalised Sylvester's equations, and global stability is ensured. Finally, simulation results are obtained to evaluate the performance of the proposed estimator and demonstrate the effectiveness of the developed scheme.
Adipose tissue segmentation in whole-body MRI

Adipose tissue volume and distribution is related to metabolic diseases such as diabetes and atherosclerosis. This relationship is in focus for much research, much due to a worldwide increase in obesity. It is in many cases of interest to calculate the amount of adipose tissue in different compartments within the body. Commonly used methods are however prone to introduce errors due to partial volume effects.Previous studies have successfully segmented three adipose tissue compartments from abdominal two-point Dixon fat-water MRI volumes using Morphon registration and atlas segmentation. This thesis extends upon the previous work by enabling segmentation of whole-body MRI volumes and by improving the registration with the use of both fat and water data. Possible methods for bone marrow segmentation are also tested and evaluated.The methods presented seem to be sufficient for creating whole-body volumes from a set of smaller volumes. The adipose tissue segmentation was adequate for subjects with relatively small volumes of adipose tissue, whereas segmentation of subjects with large amounts of adipose tissue require further improvement. Of the evaluated methods for bone marrow segmentation one seemed to perform adequately on all the tested datasets. Due to the few datasets available for testing it was not possible to draw any general conclusions as to how well the presented methods perform.
A Systematic Approach to Clustering Whole Trajectories of Mobile Objects in Road Networks

Most of mobile object trajectory clustering analysis to date has been focused on clustering the location points or sub-trajectories extracted from trajectory data. This paper presents TraceMob, a systematic approach to clustering whole trajectories of mobile objects traveling in road networks. TraceMob as a whole trajectory clustering framework has three unique features. First, we design a quality measure for the distance between two whole trajectories. By quality, we mean that the distance measure can capture the complex characteristics of trajectories as a whole including their varying lengths and their constrained movement in the road network space. Second, we develop an algorithm that transforms whole trajectories in a road network space into multidimensional data points in a euclidean space while preserving their relative distances in the transformed metric space. This transformation enables us to effectively shift the clustering task for whole mobile object trajectories in the complex road network space to the traditional clustering task for multidimensional data in a euclidean space. Third, we develop a cluster validation method for evaluating the clustering quality in both the transformed metric space and the road network space. Extensive experimental evaluation with trajectories generated on real road network maps of different cities shows that TraceMob produces higher quality clustering results and outperforms existing approaches by an order of magnitude.
ASSISTED VENTILATION IN THE POST-BYPASS PERIOD

A regime for the postoperative ventilatory management of patients who have undergone operations under cardiopulmonary bypass is described and the problems discussed. It is recommended that the endotracheal tube be left in position for 24 hours, if this can be done without the use of unduly large amounts of analgesics, and mechanical ventilatory assistance is given by a patient-triggered ventilator. If further ventilatory assistance is required, the ventilator can be used with a facepiece. Should the patient's condition deteriorate, early tracheostomy is carried out. Continuous assisted ventilation through the tracheostomy tube will maintain the patient's condition and reduce the number of cases requiring full control of ventilation. This paper describes a management Mitral plication: plastic disposable oxygenator. A slow respiratory rate with a normal carbon dioxide tension was achieved while the endotracheal tube was in position and with the assisted ventilation by the facemask the respiratory rate rose slightly, to 28 b.p.m. , then settled to a slow rate for the rest of the day, without sedation.
Serpent-handling believers

In some remote churches in East Tennessee and nearby states, Jesus' words in the sixteenth chapter of Saint Mark are taken literally: "and they shall take up serpents; and if they drink any deadly thing, it shall not hurt them. " Members of these churches describe themselves as Pentecostal-Holiness, autonomous groups of Christians with strong traditional religious views and a fundamentalist approach to biblical interpretation. Their strong faith is based largely on personal experience. Handling serpents and fire, laying on the hands of healing, speaking in tongues, and drinking poison are seen as acts of Christian obedience that demonstrate the power of the Holy Spirit. In the past these very religious people have often been distorted by the media as members of a "snake religion" or a "snake cult" because of their unorthodox beliefs and practices. Thomas Burton seeks to present a more balanced view of this generally misunderstood group in this in-depth study of serpent handlers and their religious culture. Using both oral history and scholarly research, Burton traces the evolution of Christian serpent handling from its apparent beginning in East Tennessee and explores legal and ethical issues associated with this and other unorthodox practices, allowing participants to speak for themselves through personal interviews. The result is both a dramatic presentation, through vivid photography, and a thorough analytical insight into the serpent handlers' culture.
Conserved Expression Pattern of BMP-2/4 in Hemichordate Acorn Worm and Echinoderm Sea Cucumber Embryos

Abstract The auricularia larva of sea cucumbers and tornaria larva of acorn worms share striking developmental and morphological similarities. They are regarded as not only an archetype of the nonchor-date deuterostome larva, but also an archetype of the origin of chordates. Here we report the characterization and spatial expression patterns of the BMP-2/4 genes of a hemichordate acorn worm (Pf-bmp2/4) and an echinoderm sea cucumber (Sj-bmp2/4). Both the Pf-bmp2/4 and Sj-bmp2/4 genes exhibited apparently conserved expression in the region of the coelomopore complex. This is in agreement with the homology between their basic larval body plans with respect to coelomogenesis and allows us to discuss the evolutionary counterparts of the coelomopore complex in chordates.
SONDI: audio-based device discovery and pairing for smart environments

In this paper we propose a system called SONDI that uses high frequency audio signals (called audio signatures) to pair mobile devices with fixed devices in smart environments. The system allows users to discover interaction possibilities in the environment they might have otherwise missed, through unobtrusive and non-audible signals sent from fixed devices. Benefits of SONDI include fast discovery times (<1.8 seconds), effortless interaction from the user, and high availability as SONDI does not require any additional hardware on the users' mobile devices.
Perceiving Affordances for Aperture Passage in an Environment–Person–Person System

ABSTRACT The authors investigated the perception of affordances for aperture passage in an environment–person–person (E–P–P) system, which comprised an adult perceiver and a child as a companion. Perceivers were 8 large and 8 small female undergraduates and were companioned with 1 large and 1 small girl. The perceivers perceptually judged the minimum aperture width for the E–P–P system, and then the adult–child dyads (a pair of people) actually walked through to determine the system's actual minimum aperture width. Results demonstrated that perceivers precisely judged the action capabilities of an E–P–P system on the basis of the body-scaled information of each adult–child dyad. The findings extended the previous concept of affordances for an environment-person system to affordances for an E–P–P system.
Mutational analysis of human papillomavirus type 16 E6 demonstrates that p53 degradation is necessary for immortalization of mammary epithelial cells

We have previously demonstrated that normal human mammary epithelial cells (MECs) are efficiently immortalized by human papillomavirus type 16 (HPV16) E6. HPV16 E6 binds to and induces p53 degradation in vitro and induces a marked reduction of p53 protein in MECs. Low-risk HPV6 E6 is defective for p53 binding and degradation in vitro but immortalized MECs at low efficiency. The HPV6 E6-immortalized MECs had markedly reduced levels of p53. To directly investigate whether the ability of HPV16 E6 to stimulate p53 degradation is required for E6-induced immortalization, a series of HPV16 E6 mutants were analyzed for the ability to bind and degrade p53 in vitro, induce a reduction in p53 levels in vivo, and immortalize MECs. We observed that one set of mutants efficiently immortalized MECs, caused a reduction in p53 levels in vivo, and degraded p53 in vitro. Other mutants immortalized MECs with low efficiency and either induced p53 degradation at low levels or were unable to induce p53 degradation in vitro; however, all of the immortal clones displayed low levels of p53. A third class of mutants did not immortalize MECs and failed to induce a reduction in p53 levels in vivo or degrade p53 in vitro. These results demonstrate that a reduction in p53 protein levels due to enhanced degradation is essential for MEC immortalization by HPV16 E6.
Third-Line Chemotherapy with Irinotecan plus 5-Fluorouracil in Caucasian Metastatic Gastric Cancer Patients

Purpose: The aim of this study was to evaluate the activity of the combination of 5-fluorouracil/folinic acid and irinotecan (FOLFIRI) as third-line chemotherapy (CT) in metastatic gastric cancer (mGC) patients pretreated with platinum derivatives, fluoropyrimidines, and taxanes. Methods: We prospectively collected data of mGC patients treated with third-line FOLFIRI at our institution from 2009 to 2014. Eligible patients should be treated with a fluoropyrimidine-platinum first-line CT and a subsequent taxane-based second-line CT. FOLFIRI consisted of irinotecan 180 mg/m2 and leucovorin 200 mg/m2, followed by 5-fluorouracil 2,800 mg/m2 (administered as 48-hour i.v. continuous infusion from day 1 to 3), with cycles repeated every 2 weeks. Response rate (RR) was evaluated according to RECIST version 1.0, while progression-free (PFS) and overall survival (OS) were estimated using the Kaplan-Meier method. Results: A total of 33 patients were included. The majority (97%) had good performance status (0-1 according to ECOG), while median PFS after first-line and second-line CT was 5.2 and 4.4 months, respectively. Two patients experienced an objective response (RR: 6%), while 14 patients achieved disease stabilization (disease control rate: 42%). Median PFS and OS from the start of third-line CT were 3.3 and 7.5 months, respectively. Hematological and nonhematological grade 3-4 toxicities were uncommon and included neutropenia (6.1%), diarrhea (9.1%), vomiting (3%), and asthenia (3%). Febrile neutropenia was not reported. Conclusions: Third-line CT with FOLFIRI may be an option in heavily pretreated mGC patients with preserved performance status and organ function. This regimen has a favorable safety profile, and signs of activity have been observed after standard first- and second-line CT.