Miracle-dz/UniFAR-FTUs huggingface dataset:
The socioenvironmental state: Political authority, subjects, and transformative socionatural change in an uncertain world

The ‘socioenvironmental state’ conceptualisation probes how contested, shifting, emergent boundaries of the state contain the possibilities for transformative change in the Anthropocene. The paper outlines a research programme capable of addressing the questions: who becomes authorised to govern change, who is required to make changes on the ground, and what subjectivities and pathways emerge in the context of rapid rate change? The conceptualisation unpacks three boundaries: state–society, its socionatural emergence, and the relationships between boundary-making and belonging to address these questions and better account for the successes and failures of attempts at governing an uncertain, rapidly changing world. In this analysis, ‘environmental change’ arises as a stochastic, relational becoming – ecologies and resources are emergent with the social-politics of governing them – suggesting that more analytical attention is required on how ‘environmental challenges’ and their ‘drivers of change’ are conceived and delimited. Together, these theoretical insights help reveal the way that the micro-politics of local resource use and the contradictory acceptance and refusals of authority and subjection are not only products of, but also productive of, larger scale political economies, socionatures, governance, and political struggles. The aim is to contribute towards a re-imagination of political authority that begins to capture the complex interplay between our attempts at governing a changing world and the inadvertent authorisations, inclusions, and exclusions that we produce in those efforts. The paper partially illustrates the conceptual ideas with an account of forestry and climate change in Nepal. In a context wherein programmes to govern resources have become of global concern, probing the implications of these points is crucial. It is not only that states govern resources with particular consequences for ‘environmental change’ or ‘sustainability’, but also that the act of governing resources (re)produces the socioenvironmental boundaries of the state with profound implications for how future transformations can unfold.
Social media research in the context of emerging markets

Purpose Despite the potential of social media in emerging markets (EMs), only a few studies published in high-quality information systems (IS) journals that have addressed issues related to social media in the context of EMs. The purpose of this paper is to analyse existing research related to social media published in high-quality IS journals for exploring initial research trends, emerging themes, limitations and future research directions in the context of EMs. Design/methodology/approach This study conducted a systematic review of 22 articles on social media, which were published in the “Senior Scholars Basket of IS Journals and Information Systems Frontiers” from 1997 to 2017. Manual literature search approach (i.e. screening through the table of contents of each journal) was employed to identify relevant articles. The content of relevant articles was systematically analysed and synthesised along with keyword analysis to understand research trends on social media related issues in the EMs context. Findings The study identified four major themes from existing research on the social media in the context of EMs, namely: social media frameworks; social media and consumers; social media and organisations; and social media and society with the majority of the studies focussing on consumers. A single subject was found as the major limitation with studies analysed focussing on single platform/country/domain hindering the generalisability whereas including a new exogenous variable to improve the validity of existing studies emerged as main future research direction. Originality/value This study conducted literature review on social media in EMs, which have not been undertaken yet. Moreover, it employed manual search (an effort and time-intensive approach) to overcome the shortcomings of keyword search to identify, locate, select and analyse the social media literature in the context of EMs.
Secure Data Access Control With Ciphertext Update and Computation Outsourcing in Fog Computing for Internet of Things

Fog computing is a paradigm that extends cloud computing to the edge of the network. It can provide computation and storage services to end devices in Internet of Things (IoT). Attribute-based cryptography is a well-known technology to guarantee data confidentiality and fine-grained data access control. However, its computational cost in encryption and decryption phase is linear with the complexity of policy. In this paper, we propose a secure and fine-grained data access control scheme with ciphertext update and computation outsourcing in fog computing for IoT. The sensitive data of data owner are first encrypted using attribute-based encryption with multiple policies and then outsourced to cloud storage. Hence, the user whose attributes satisfy the access policy can decrypt the ciphertext. Based on the attribute-based signature technique, authorized user whose attributes integrated in the signature satisfy the update policy can renew the ciphertext. Specifically, most of the encryption, decryption, and signing computations are outsourced from end devices to fog nodes, and thus, the computations for data owners to encrypt, end users to decrypt, re-encrypt, and sign are irrelevant to the number of attributes in the policies. The security analysis shows that the proposed scheme is secure against known attacks, and the experimental results show that the fog nodes perform most of the computation operations of encryption, decryption, and signing, and hence, the time of encryption for data owner, decryption, re-encryption, and signing for users is small and constant.
The prevalence of sedentary behaviours and physical activity in Hungarian youth.

BACKGROUND The study of sedentary behaviour is becoming much more visible, alongside research on physical activity. Few published studies, however, originate from Eastern or Central Europe. METHOD Prevalence and point estimate data of key leisure time sedentary and active behaviours are reported from Hungary, a country that has been through an important political transition in the past two decades. Participants (n = 301) aged 13-18 years completed time-use diaries over 4 days for time outside of school. Sedentary and active behaviours were coded and analysed. RESULTS TV viewing reflected trends found elsewhere and was the most prevalent sedentary behaviour. Physical activity levels were low. The next most time-consuming sedentary weekday activities were homework, motorized transport, sitting and talking and playing computer/video games. Gender differences were different to some other countries, with girls reporting more computer game use and boys more sitting and talking, but these may reflect cultural and reporting differences. CONCLUSION This study provides the first comprehensive description of sedentary behavioural prevalence in Hungarian youth.
Trichloroethylene degradation by two independent aromatic-degrading pathways in Alcaligenes eutrophus JMP134

The bacterium Alcaligenes eutrophus JMP134(pJP4) degrades trichloroethylene (TCE) by a chromosomal phenol-dependent pathway and by the plasmid-encoded 2,4-dichlorophenoxyacetic acid pathway. The two pathways were independent and exhibited different rates of removal and capacities for quantity of TCE removed. The phenol-dependent pathway was more rapid (0.2 versus 0.06 nmol of TCE removed per min per mg of protein) and consumed all detectable TCE. The 2,4-dichlorophenoxyacetic acid-dependent pathway removed 40 to 60% of detectable TCE.
Coat protein-mediated resistance as an approach for controlling an Egyptian isolate of Cucumber mosaic virus (subgroup I)

Cucumber mosaic virus (CMV, cucumovirus) is the most important virus infecting cucurbit crops in Egypt and worldwide causing significant loss in yield quality and quantity. The main target of the present work was to establish a simple controlling system for an Egyptian isolate of such virus (belonging to the subgroup I) via production of tobacco transgenic plants expressing viral coat protein (CP). Coat protein gene (cp) was isolated and amplified using immunocapture-reverse transcriptase-polymerase chain reaction (IC-RT-PCR) and primers with add-on restriction sites for SmaI and SacI enzymes. The genes were cloned in pBI121 vector plasmid between the CaMV 35S promoter and the nos terminator after removing the Gus gene by restriction enzymes digestion. The new construct was used for Agrobacterium tumefaciens transformation, which was then used for tobacco transformation. Evaluation of transformation success and CP expression degree were confirmed using indirect enzyme-linked immunosorbent assay (I-ELISA) and dot blot immuno-binding assay (DBIA). PCR and RT-PCR were used to study the integration of cp within genetic plant system and to what extent this gene was transcript. It was concluded that in spite of integration success some transformed plants can transcript the gene more than the others do. Plants resistance was tested by challenging with CMV under study and remarkable success was obtained in plants with higher gene transcription and translation degree.
A comparative proteomic analysis of blood serum for developmental stages in pigs

This study aimed to differentiate genes at developmental stages of pigs from 0 to 150 days of age, to build up a protein database and to find candidate genetic markers for growth traits. The analysis of two-dimensional electrophoresis and matrix-assisted laser-desorption/ionization mass spectrometry separated 252 protein segments. After successfully blasting the peptide sequences, the analysis confirmed 37 differentially expressed proteins that increased from birth to 150 days of age (type A), whereas the type B proteins presented the inverse pattern. The type C proteins included proteins that were expressed continuously throughout the developmental periods. A total of 319 primer sets for 33 genes were designed to find genetic variants using pooled DNA samples of Yorkshire pigs. Amplification products for all primer sets produced approximately 20 000 clones that were sequenced, and 48 candidate SNP sites were finalized for genotyping. A total of 475 animals were used for high throughput genotyping analysis. Among these, phenotype data of all 475 animals were collected for average daily gain, backfat thickness and days to 90 kg, whereas feed conversion data were collected for 300 animals and body measurement traits (starting weight, ending weight, body length, wither height and chest depth) were collected for 209 animals. Association analysis found significant statistical differences between the animals having genotypes of 13 SNPs (g.78935883C>T, g.147629986C>T, g.98266037T>C, g.214707340G>A, g.88350299C>T, g.17180956C>T, g.17181024C>T, g.2350283A>G, g.138361311C>T, g.44996379C>T, g.44996247A>C, g.107715245C>T, g.4149631C>T) for the various measured traits. The identified genetic polymorphisms, of which one was novel (g.214707340G>A), may serve as candidate molecular markers to change population means for the targeted growth traits.
Repetitive control based tremor suppression using electrical stimulation

Tremor is a common, debilitating movement condition commonly occurring in neurological disorders, with invasive and pharmacological treatment methods often ineffective. Functional electrical stimulation (FES) holds potential to supress tremor, but previous control methods have proven of limited success. This paper establishes the feasibility of using repetitive control, a framework which is able to eliminate the effect of periodic disturbances by including an internal model of the oscillation within the control structure. A model of the wrist is developed and two different repetitive control algorithms are applied to suppress tremor via stimulation of wrist flexors and extensors. Experimental results are compared with filter-based methods to establish the efficacy of the proposed approach.
Estimation of the plasma effect site equilibration rate constant of sufentanil in children using the time to peak effect of heart rate and blood pressure

Objectives: Although targeting the effect site concentration may offer advantages over the traditional forms of administering intravenous anesthetics, it is not applicable for sufentanil in children because its plasma effect site equilibration rate constant (ke0) is not known yet. We estimated ke0 of sufentanil in children using the time to peak effect (tpeak) method. Materials and Methods: Under general anesthesia, sufentanil tpeak was measured after administration of a submaximal bolus dose by means of the decrease in heart rate, blood pressure and calculated approximate entropy (ApEn) of electroencephalogram in 105 children (age range: 3–11 years). ke0 was estimated using tpeak and known sufentanil pharmacokinetic parameters in normal children. Results: The mean tpeaks were measured as 44 ± 22 s and 227 ± 91 s by heart rate and by mean blood pressure respectively. The estimated ke0 were 5.16/min and 0.49/min by heart rate and blood pressure respectively. tpeak could not be measured using the ApEn, thus ke0 could not be calculated by ApEn in children. Conclusions: Shorter measured sufentanil tpeak by heart rate compared to blood pressure indicate that the heart rate decrease faster than decreasing of blood pressure. Moreover, the calculated sufentanil ke0 in children depends on the pharmacodynamics parameters.
Combination therapy of atorvastatin and amlodipine inhibits sympathetic nervous system activation and improves cognitive function in hypertensive rats.

BACKGROUND A previous study has demonstrated that orally administered atorvastatin reduces sympathetic nervous system (SNS) activation via an anti-oxidant in the rostral ventrolateral medulla (RVLM) of hypertensive rats, whereas amlodipine did not. Furthermore, several previous reports have suggested that atorvastatin or amlodipine improves cognitive dysfunction during hypertension. The aim of the present study was to determine whether a combination of atorvastatin and amlodipine causes sympathoinhibition via reduction of oxidative stress in the RVLM and improves cognitive dysfunction of hypertensive rats. METHODS AND RESULTS Stroke-prone spontaneously hypertensive rats (SHRSPs), as a hypertensive model with sympathoexcitation, were divided into 4 groups; a combination of atorvastatin and amlodipine-treated (COM), atorvastatin-treated (ATR), amlodipine-treated (AML), hydralazine-treated (HYD), and vehicle-treated SHRSPs (VEH). After treatment for 28 days, the mean blood pressure did not change in ATR rats, and was reduced to the similar levels in COM, AML, and HYD rats. However, SNS activation and oxidative stress in the RVLM were significantly lower only in COM than in ATR, AML, HYD, and VEH rats. Cognitive performance and manganese-superoxide dismutase activity in the hippocampus were significantly higher, and oxidative stress in the hippocampus was significantly lower in COM than in VEH, AML, and HYD rats to a greater extent than in ATR rats. CONCLUSIONS A combination of atorvastatin and amlodipine causes sympathoinhibition via an anti-oxidant in the RVLM and improves cognitive dysfunction via an anti-oxidant in the hippocampus in hypertensive rats, independent of the blood pressure-lowering effect.
Identification of antigenic sites on three hepatitis C virus proteins using phage‐displayed peptide libraries

A novel approach to screening phage‐displayed peptide libraries has been used to identify hepatitis C virus (HCV) core, NS4 and NS5 sequences, which are antigenic in humans. Two random peptide libraries were used for screening using a mixture of HCV‐positive sera or individual antibodies to core, NS3, NS4, and NS5 HCV proteins affinity‐purified from this mixture. Sequencing of 56 selected phage clones resulted in 28 different peptide sequences and identification of seven antigenic regions, three in the core protein (19‐26, 34‐49, and 73‐83), three in the NS4 (1681‐1693, 1712‐1718, and 1726‐1736) and one in the NS5 protein (2251‐2260). No NS3‐specific peptides were identified. The immune response to core, NS4 and NS5 proteins includes a variety of linear determinants whereas epitopes on the investigated part of NS3 protein appear to be conformation‐dependant. J. Med. Virol. 56:105–111, 1998. © 1998 Wiley‐Liss, Inc.
Laser‐capture microdissection and transcriptional profiling of the dorsomedial nucleus of the hypothalamus

Identifying neuronal molecular markers with restricted patterns of expression is a crucial step in dissecting the numerous pathways and functions of the brain. While the dorsomedial nucleus of the hypothalamus (DMH) has been implicated in a host of physiological processes, current functional studies have been limited by the lack of molecular markers specific for DMH. Identification of such markers would facilitate the development of mouse models with DMH‐specific genetic manipulations. Here we used a combination of laser‐capture microdissection (LCM) and gene expression profiling to identify genes that are highly expressed within the DMH relative to adjacent hypothalamic regions. Six of the most highly expressed of these genes, Gpr50, 4930511J11Rik, Pcsk5, Grp, Sulf1, and Rorβ, were further characterized by real‐time polymerase chain reaction (PCR) analysis and in situ hybridization histochemistry. The genes identified in this article will provide the basis for future gene‐targeted approaches for studying DMH function. J. Comp. Neurol. 520:3617–3632, 2012. © 2012 Wiley Periodicals, Inc.
The Mediating Role of Perception in the Relationship between Expectation and Satisfaction in Terms of Sustainability in Tourism Education

Education plays a central role in shaping individual and social change toward sustainability. Sustainable tourism education provided by the higher education institutions which offer education at the undergraduate level has an important role in training candidate managers and meeting the need for qualified labor in the tourism sector in terms of sustainable tourism. The purpose of this study is to examine the relationship among expectation, perception, and satisfaction of the undergraduate students receiving tourism education at the tertiary level. It is also aimed to reveal the mediating role of perception between expectation and satisfaction. One of the quantitative methods used in the research process was the causative and correlational model. A total of 675 students participated in this survey conducted at the Tourism Faculty of Akdeniz University. To collect data, expectation of tourism education, perception of tourism education, and satisfaction of academic education scales were used. In the data analysis, parametric tests, t-test, ANOVA, correlation, and regression analyses were applied. In this study, it was revealed that 675 students receiving tourism education at the undergraduate level came to school with moderate-level expectations, their perceptions fulfilled their expectations with the experience they had, and their satisfaction levels that emerged as a result of their perceptions were at a moderate level as well. As a result of the t-test performed, it was put forward that there was no difference in their level of satisfaction based on the gender variable; however, a significant difference was determined based on the high school type from which a subject graduated, the current department, class, and age variables. As a result of the correlation analysis, a positive relation was identified between the expectation, perception, and satisfaction variables. The multiple regression analysis indicated that expectation positively affected perception and satisfaction; therewithal, perception affected satisfaction and its sub-dimensions positively. It was also found that the perception had a partial mediating role between expectation and satisfaction in education.
Detection of Helicobacter pullorum in meat chickens in Australia.

The bacterial genus Helicobacter is a member of the Campylobacteriales in the Epsilonproteobacteria subphylum, and is comprised of organisms that are morphologically similar to Campylobacter. The term ‘campylobacteria’ is used to encompass the genera Campylobacter, Arcobacter, Helicobacter and Anaerobiospirillum. Helicobacter was separated from the genus Campylobacter in 1989. Helicobacter spp have been isolated from gastric tissue or intestinal contents of humans and a wide range of animal species, with some associated with disease.
Impersonal smartphone-based activity recognition using the accelerometer sensory data

Smartphone-based activity recognition focuses on identifying the current activities of a mobile user by employing the sensory data which are available on smartphones. A lightweight model and less inquiry users for true activities, are necessary for deploying the activity recognition on a mobile platform for identifying activities based on new sensory data in real time. In this paper, we propose a new smartphone-based activity recognition framework for evolving sensory data stream called ISAR. It stands for Impersonal Smartphone-based Activity Recognition. ISAR model is built using annotated sensory data from a panel of user as training data and are applied to the new users. Our new model is an offline and online phase. In offline phase, we propose a new method for finding the threshold value which used to distinguish between dormant activities and energetic activities. Only a set of the energetic activities are used to build a light-weight classifier model. In online phase, we introduce the recognition technique of unannotated streaming sensory data with different activities. The experimental results using real human activity recognition data have conducted and compared with STAR model in terms of the accuracy and time complexity. Our results indicates that ISAR model can perform dramatically better than STAR model. Moreover, ISAR can utilize better than STAR model in real situation, especially across different users and without inquiry users.
Exercise training augments flow-dependent dilation in rat skeletal muscle arterioles. Role of endothelial nitric oxide and prostaglandins.

We aimed to test the hypothesis that as a consequence of short-term daily exercise, flow (shear stress)-dependent dilation and its mediation by the endothelium are altered in skeletal muscle arterioles. After initial familiarization with the protocol, rats ran on a treadmill once a day (with gradually increasing intensity up to 40 minutes and 28 m/min) for approximately 3 weeks (EX group); a control group remained sedentary (SED group). The active (internal) diameters of isolated gracilis muscle arterioles of SED and EX rats at 80 mm Hg were significantly different (55.2 +/- 2.1 and 49.3 +/- 2.0 microns, P < .05), and their passive diameters (in Ca(2+)-free solution) were 105.3 +/- 3.1 and 111.2 +/- 2.4 microns (not significantly different), respectively. Increases in flow of the perfusion solution from 0 to 12 microL/min elicited a significantly greater increase in diameter of EX arterioles (by 83.5% at maximum flow). This enhanced sensitivity maintained a lower shear stress in EX arterioles (15 to 20 dyne/cm2) compared with SED arterioles (25 to 35 dyne/cm2). In both SED and EX arterioles, flow-dependent dilation was eliminated after removal of the endothelium. Either N omega-nitro-L-arginine, a nitric oxide synthase inhibitor, or indomethacin, an inhibitor of prostaglandin synthesis, shifted the flow-diameter and calculated wall shear stress-diameter curves significantly to the right. Each of the inhibitors reduced flow-dependent dilation to a similar degree (approximately 40% to 45%); their combined administration nearly completely eliminated the dilation of arterioles of both SED and EX rats. (ABSTRACT TRUNCATED AT 250 WORDS)