Miracle-dz/UniFAR-FTUs huggingface dataset:
Predictors of Intention to Refer to Pediatric Palliative or Hospice Care

The purpose of this descriptive correlational study was to determine whether nurse characteristics, level of comfort with care of the dying, and spirituality predict intention to refer and timing of referral to pediatric palliative/hospice care. The Behavioral Model of Health Services Use served as the framework for this study. Data were collected from 105 pediatric nurses recruited from 7 patient units of one pediatric hospital. Regression analysis revealed several nurse factors (practice unit, years of experience, age, race/ethnicity) that predicted intent to refer and timing of referral to pediatric palliative/hospice care. The relationship between nurse characteristics and intent to refer was specific to certain medical conditions (HIV, extreme prematurity, brain injuries). Healthcare providers can use these findings to improve care for children with life-limiting illnesses.
Certification of NIST SRM 1962: 3 μm Diameter Polystyrene Spheres

This report describes the certification of SRM 1962, a NIST Standard Reference Material for particle diameter. It consists of an aqueous suspension of monosize 3 (μm polystyrene spheres. Two calibration techniques were used: optical microscopy and electron microscopy. The first one gave a mean diameter of D¯=2.977±0.011 μm and a standard deviation of the size distribution σD = 0.020 μm, based on measurement of 4600 spheres. The second technique gave D¯=2.990±0.009 μm, based on measurement of 120 spheres. The reported value covering the two results is D¯=2.983 μm with a maximum uncertainly of 0.016 μm, with σD=0.020 μm.
Reanalysis of a tailored web-based exercise programme for office workers with sub-acute low back pain: Assessing the stage of change in behaviour

Objective: To reanalyse a web-based intervention for physically untrained office workers with sub-acute non-specific low back pain in low back pain-related exercise behaviour terms. Design: Reanalysis of a randomized controlled trial. Setting: Occupational Preventive Medicine of University. Methods: Participants were randomized to an intervention group (proposed intervention plus standard care) or a control group (usual care only). The intervention exercise and education materials were developed as an online resource, and included video demonstrations recorded in a laboratory. Resources were loaded onto a dedicated section of the University Preventive Medicine Service website. All sessions included stretching, and exercises to improve postural stability (abdominal, lumbar, hip and thigh muscles) strength, flexibility and mobility. Outcome measures were self-reported health status (visual analogue scale (VAS) of the Euroquol-5D questionnaire); functional health status (Oswestry disability questionnaire); and the stage of change questionnaire. At nine months, outcomes in the intervention group were analysed and compared with baseline and outcomes in controls. Results: In the intervention group, significant positive effects were observed at nine-month follow up for stage of change in the behavioural domain as related with low back pain for all phases except for the contemplation phase. The positive change in the stage of change questionnaire correlated with the improvement observed in Oswestry (r = .388) and VAS (r = −.612). Conclusions: The reanalysis of the trial suggests that exercise behaviour related to low back pain improve after the intervention period. This improvement correlates with changes in clinical low back pain-related outcomes.
Updatable Island Reasoning for Alchi-ontologies

In the last years, the vision of the Semantic Web fostered the interest in reasoning over ever larger sets of assertional statements in ontologies. It is easily conjectured that, soon, real-world ontologies will not fit into main memory anymore. If this was the case, state-of-the-art description logic reasoning systems cannot deal with these ontologies any longer, since they rely on in-memory structures. We propose a way to overcome this problem by reducing instance checking for an individual in an ontology to a (usually small) relevant subsets of assertional axioms. These subsets are computed based on a partitioningcriteria. We propose a way to preserve the partitions while updating an ontology and thus enable stream like reasoning for description logic ontologies. We think that this technique can support description logic systems to deal with the upcoming large amounts of fluctuant assertional data.
Effect of a DC Stray Current on the Corrosion of X80 Pipeline Steel and the Cathodic Disbondment Behavior of the Protective 3PE Coating in 3.5% NaCl Solution

The influence of a direct current (DC) stray current on the corrosion and cathodic disbondment of X80 steel coated with a polyethylene (3PE) coating in 3.5% NaCl solution was studied by immersion experiments, electrochemical tests, three-dimensional microscopy, and a surface analysis. The results showed that the potential of the X80 steel sample shifts under the direct current. After 100A/m2 DC interference was applied, the potential of the sample in the anode region positively shifted from –0.68 to –0.43 V. At the same time, the sample in the cathode region negatively shifted to –1.45 V. Under the DC anode action, the X80 steel corrosion exhibited no passivation and followed Faraday’s law of electrolysis, in which the corrosion rate is proportional to the current density. Three-dimensional (3D) digital microscopy showed that, as the DC current increased, the depth of the corrosion pit also increased (gradually), indicating a higher corrosion degree. The sample in the cathode region only underwent a hydrogen evolution reaction, which caused cathodic disbondment of the coating. The stray current had a critical current density for the coating disbonding: the coating delamination area reached its maximum and then remained unchanged.
The second INTEGRAL AGN catalogue

Aims. The INTEGRAL mission provides a large data set for studying the hard X-ray properties of AGN and allows testing of the unified scheme for AGN. Methods. We present analysis of INTEGRAL IBIS/ISGRI, JEM-X, and OMC data for 199 AGN supposedly detected by INTEGRAL above 20 keV. Results. The data analysed here allow significant spectral extraction on 148 objects and an optical variability study of 57 AGN. The slopes of the hard X-ray spectra of Seyfert 1 and Seyfert 2 galaxies are found to be consistent within the uncertainties, whereas higher cut-off energies and lower luminosities we measured for the more absorbed/type 2 AGN. The intermediate Seyfert 1.5 objects exhibit hard X-ray spectra consistent with those of Seyfert 1. When applying a Compton reflection model, the underlying continua appear the same in Seyfert 1 and 2 with Γ � 2, and the reflection strength is about R � 1, when assuming different inclination angles. A significant correlation is found between the hard X-ray and optical luminosity and the mass of the central black hole in the sense that the more luminous objects appear to be more massive. There is also a general trend toward the absorbed sources and type 2 AGN having lower Eddington ratios. The black hole mass appears to form a fundamental plane together with the optical and X-ray luminosity of the form LV ∝ L 0.6 X M 0.2 BH , similar to what is found between LR, LX ,a ndMBH. Conclusions. The transition from the type 1 to type 2 AGN appears to be smooth. The type 2 AGN are less luminous and have less accreting super massive black holes. The unified model for Seyfert galaxies seems to hold, showing in hard X-rays that the central engine is the same in Seyfert 1 and 2, but seen under different inclination angles and absorption. The fundamental plane links the accretion mechanism with the bulge of the host galaxy and with the mass of the central engine in the same way in all types of Seyfert galaxies.
Reconstructed Precipitation Tritium Leads to Overestimated Groundwater Recharge

Time series of precipitation tritium contents are often used for groundwater recharge estimation based on the tritium mass ratio of the (un) saturated zones to precipitation. But records of the precipitation tritium measurements are sparse and often need to be reconstructed. Uncertainties associated with reconstructed records can affect the recharge estimates, but this has received little attention. Here we leverage four >15 m deep, exceptionally well preserved unsaturated zone tritium profiles to quantify the uncertainty in Tritium mass balance from precipitation tritium reconstruction. The tritium profiles have bomb tritium peaks at 7.2–10.5 m below the surface and peaks ranging from 46 to 235 tritium unit. We first estimate the diffuse recharge by the tritium peak method. Since this method is independent of any precipitation tritium reconstruction, the estimated recharge was used as truth to evaluate four precipitation tritium reconstruction methods: two interpolation methods and two reference curve methods. Direct comparison between the observed and simulated precipitation tritium showed that the reference curve methods performed more poorly than the interpolation methods. Indirect evaluation by comparing the recharge rates estimated by the tritium storage method with our truth measurements showed that tritium storage method overestimated recharge by 100% to 200%. Our results suggest that the atmospheric tritium flux was greatly underestimated, especially by the reference curve methods. As such, groundwater recharge at our sites would be overestimated. This has implications for using these standard approaches elsewhere.
An English to Korean Transliteration Model of Extended Markov Window

Automatic transliteration problem is to transcribe foreign words in one's own alphabet. Machine generated transliteration can be useful in various applications such as indexing in an information retrieval system and pronunciation synthesis in a text-to-speech system. In this paper we present a model for statistical English-to-Korean transliteration that generates transliteration candidates with probability. The model is designed to utilize various information sources by extending a conventional Markov window. Also, an efficient and accurate method for alignment and syllabification of pronunciation units is described. The experimental results show a recall of 0.939 for trained words and 0.875 for untrained words when the best 10 candidates are considered.
Ocular morbidity prevalence among school children in Shimla, Himachal, North India

Background Data on eye diseases among school children is not readily available. Considering the fact that one-third of India's blind lose their eyesight before the age of 20 years and many of them are under five when they become blind, early detection and treatment of ocular morbidity among children is important. Aim To estimate the prevalence of ocular morbidity among school children of age 6-16 years. Settings Government and private coeducational schools in urban area of Shimla. Design Cross-sectional Materials and Methods Government and private coeducational schools selected by stratified random sampling. About 1561 school children, studying in elementary through secondary class in these schools were examined from August 2001 to January 2002 in Shimla. A doctor did visual acuity and detailed ophthalmic examination. Statistical analysis The Chi-square test was used to test differences in proportions. Differences were considered to be statistically significant at the 5% level. Results Prevalence of ocular morbidity was 31.6% (CI=29.9-32.1%), refractive errors 22% (CI=21.1-22.8%), squint 2.5% (CI=2.4-2.6%), color blindness 2.3% (CI=2.2-2.4%), vitamin A deficiency 1.8 % (CI=1.7-1.9%), conjunctivitis 0.8% (CI=0.79-0.81%). Overall prevalence of ocular morbidity in government and private schools did not show any statistical significant difference. Prevalence of conjunctivitis was significantly (P<0.5) more in government schools. Conclusion A high prevalence of ocular morbidity among high-school children was observed. Refractive errors were the most common ocular disorders.
EYE MOVEMENTS AND SCHIZOPHRENIA

SUMMARY Smooth pursuit eye movements (SPEM) has been reported to be abnormal in schizophrenic patients. 30 schizophrenic patients and 15 normal subjects were examined for the quality of their smooth pursuit performance. 73.33% of the schizophrenics and 40% of the normal subjects had ‘impaired’ pursuit performance. The significance of the findings has been discussed.
Structures and dynamics investigation of phase selection in metallic alloy systems

Different phases of metallic alloys have a wide range of applications. However, the driving mechanisms of the phase selections can be complex. For example, the detailed pathways of the phase transitions in the devitrification process still lack a comprehensive interpretation. So, the understanding of the driving mechanisms of the phase selections is very important. In this thesis, we focus on the study of the Al-Sm and other related metallic alloy systems by simulation and experiment. A procedure to evaluate the free energy has been developed within the framework of thermodynamic integration, coupled with extensive GPUaccelerated molecular dynamics (MD) simulations; The “spatially-correlated site occupancy” has been observed and measured in the -Al60Sm11 phase. Contrary to the common belief that nonstoichiometry is often the outcome of the interplay of enthalpy of formation and configurational entropy at finite temperatures, our results from Monte Carlo (MC) and molecular dynamics (MD) simulations, imply that kinetic effects, especially the limited diffusivity of Sm is crucial for the appearance of the observed spatial correlations in the nonstoichiometric phase. Moreover, in order to overcome the time limitation in MD simulation of the nucleation process, a “persistent-embryo method” has been developed, which opens a new avenue to study solidification under realistic experimental conditions via atomistic computer simulation. Based on this thesis study, we have achieved deeper understanding of the driving mechanisms of the phase selections, and laid a foundation for further prediction and control of the fabrication of novel metallic alloy materials. This thesis consists of the following seven chapters:
Elevated phosphatase of regenerating liver 3 (PRL-3) promotes cytoskeleton reorganization, cell migration and invasion in endometrial stromal cells from endometrioma.

STUDY QUESTION Is phosphatase of regenerating liver-3 (PRL-3) associated with increased motility of endometriotic cells from endometrioma? SUMMARY ANSWER Elevated PRL-3 promotes cytoskeleton reorganization, cell migration and invasion of endometrial stromal cells (ESCs) from endometrioma. WHAT IS KNOWN ALREADY Overexpression of PRL-3 is associated with cancer cell migration, invasion and metastatic phenotype. STUDY DESIGN, SIZE, DURATION Primary human ESCs were isolated from eutopic endometrium of women without endometriosis (EuCo, n = 10), with histologically proven endometrioma (EuEM, n = 19) and from the cyst wall of ovarian endometriosis (OvEM, n = 26). PARTICIPANTS/MATERIALS, SETTING, METHODS The expression of PRL-3 in ESCs derived from EuCo, EuEM and OvEM at different phases of menstrual cycle were compared. The protein and mRNA levels of PRL-3 were examined by western blot and RT-qPCR, respectively. ESCs from OvEM were transfected with/without short hairpin RNA (shRNA) or small interfering RNA (siRNA). Additionally, a plasmid-mediated delivery system was used to achieve PRL-3 overexpression in ESCs from EuEM. The cellular distribution of F-actin and α-tubulin were examined by immunocytochemistry. Cell motility was evaluated by a transwell migration/invasion assay. MAIN RESULTS AND THE ROLE OF CHANCE The protein and mRNA levels of PRL-3 are significantly elevated in ESCs from OvEM compared with EuCo and EuEM. The expression of PRL-3 was not altered between proliferative phase and secretory phase in ESCs from all groups. Knockdown of PRL-3 significantly modified the distribution of F-actin and α-tubulin cytoskeleton, inhibited cell migration and invasion. Endogenous inhibition of PRL-3 attenuated the expression of Ras homolog gene family members A and C (RhoA, RhoC), Rho-associated coiled-coil-containing protein kinase 1 (ROCK1) and matrix metalloproteinase (MMP) 9, but not MMP2 in ESCs from OvEM. Additionally, overexpression of PRL-3 in ESCs from EuEM up-regulates cell migration and invasion, and increases the expression of RhoA, RhoC, ROCK1 and MMP9. LIMITATIONS, REASONS FOR CAUTION Lack of in vivo animal studies is the major limitation of our report. Our results should be further confirmed in a larger cohort of patients and extended to include eutopic and ectopic endometrium from patients with peritoneal endometriosis at different stages of the disease. WIDER IMPLICATIONS OF THE FINDINGS Our study describes that elevated expression of PRL-3 contributes to the cell motility of ESCs from endometrioma. The results emphasize the importance of metastatic-related factor PRL-3 in the pathogenesis of endometrioma. STUDY FUNDING/COMPETING INTEREST This work was supported by National Natural Science Foundation of China (No. 81170546) and Zhejiang Medicine Science and Technology Projects (No. Y13H040003). The authors declare no conflict of interest.
Post-Quantum Key Exchange for the TLS Protocol from the Ring Learning with Errors Problem

Lattice-based cryptographic primitives are believed to offer resilience against attacks by quantum computers. We demonstrate the practicality of post-quantum key exchange by constructing cipher suites for the Transport Layer Security (TLS) protocol that provide key exchange based on the ring learning with errors (R-LWE) problem, we accompany these cipher suites with a rigorous proof of security. Our approach ties lattice-based key exchange together with traditional authentication using RSA or elliptic curve digital signatures: the post-quantum key exchange provides forward secrecy against future quantum attackers, while authentication can be provided using RSA keys that are issued by today's commercial certificate authorities, smoothing the path to adoption. Our cryptographically secure implementation, aimed at the 128-bit security level, reveals that the performance price when switching from non-quantum-safe key exchange is not too high. With our R-LWE cipher suites integrated into the Open SSL library and using the Apache web server on a 2-core desktop computer, we could serve 506 RLWE-ECDSA-AES128-GCM-SHA256 HTTPS connections per second for a 10 KiB payload. Compared to elliptic curve Diffie-Hellman, this means an 8 KiB increased handshake size and a reduction in throughput of only 21%. This demonstrates that provably secure post-quantum key-exchange can already be considered practical.
Beneficial effects of statins after percutaneous coronary intervention

Background Evidence about the efficacy of statin treatment among patients after percutaneous coronary intervention (PCI) is very limited. The rapid advancement in PCI technology and near universal use of adjunctive cardioprotective medications make it necessary to formally assess the effect of statin therapy on cardiac events after PCI. Design This was a multicenter prospective cohort study. Methods Patients who received stent implantation and survived to hospital discharge from the National Heart, Lung, and Blood Institute Dynamic Registry from 2004 to 2006 formed the study cohort. Patients with cardiogenic shock, in-hospital adverse events [including myocardial infarction and coronary artery bypass graft surgery (CABG)], liver disease, renal disease, alcoholism, or drug abuse were excluded. The occurrences of death, CABG, and repeat PCI, and repeat revascularization were collected over 1-year follow-up. Results Of the 3227 patients evaluated, 2737 (85%) were prescribed a statin at discharge. By 1-year follow-up, incident events were 98 deaths, 44 CABG, 290 repeat PCI procedures, and 328 repeat revascularizations. After propensity score adjustment, postdischarge statin therapy was associated with lower risks of death [hazard ratio (HR): 0.58, 95% confidence interval (CI): 0.36–0.93, P = 0.02], CABG (HR: 0.49, 95% CI: 0.24–1.00, P = 0.05), and repeat revascularization (HR: 0.74, 95% CI: 0.56–1.00, P = 0.05). Conclusion These results support the routine use of statin therapy after PCI.
Perspective rectification for mobile phone camera-based documents using a hybrid approach to vanishing point detection

Documents captured by a mobile phone camera often have perspective distortions. In this paper, a fast and robust method for rectifying such perspective documents is presented. Previous methods for perspective document correction are usually based on vanishing point detection. However, most of these methods are either slow or unstable. Our proposed method is fast and robust with the following features: (1) robust detection of text baselines and character tilt orientations by heuristic rules and statistical analysis; (2) quick detection of vanishing point candidates by clustering and voting; and (3) precise and efficient detection of the final vanishing points using a hybrid approach, which combines the results from clustering and projection analysis. Our method is evaluated with more than 400 images including paper documents, signboards and posters. The image acceptance rate is more than 98% with an average speed of about 100ms.
Ostracism via virtual chat room—Effects on basic needs, anger and pain

Ostracism is characterized by a social pain provoked by being excluded and ignored. In order to address the effects of social ostracism in virtual non-physical interactions, we developed a more realistic paradigm as an alternative to Cyberball and assessed its effects on participant’s expression of basic social needs, emotional experience and painful feeling. The chat room consisted of controlled social dialogue interactions between participants and two other (confederate) chat room partners. Exclusion was manipulated by varying the number of messages a participant received (15% and 33% in exclusion and inclusion, respectively). Analysis of participant (N = 54) responses revealed that exclusion induced a lower experience of basic-need states and greater anger, compared with included participants. In addition, excluded participants reported higher levels of two specific self-pain feelings, namely tortured and hurt. Our findings suggest that this procedure is effective in inducing social ostracism in a realistic and yet highly controlled experimental procedure.
Architectural Support For Translation Table Management In Large Address Space Machines

Virtual memory page translation tables provide mappings from virtual to physical addresses. When the hardware controlled Translation Lookaside Buffers (TLBs) do not contain a translation, these tables provide the translation. Approaches to the structure and management of these tables vary from full hardware implementations to complete software based algorithms. The size of the virtual address space used by processes is rapidly growing beyond 32 bits of address. As the utilized address space increases, new problems and issues surface. Traditional methods for managing the page translation tables are inappropriate for large address space architectures. The Hashed Page Table (HPT), described here, provides a very fast and space efficient translation table that reduces overhead by splitting TLB management responsibilities between hardware and software. Measurements demonstrate its applicability to a diverse range of operating systems and workloads and, in particular, to large virtual address space machines. In simulations of over 4 billion instructions, improvement of 5 to 10% were observed.