Miracle-dz/UniFAR-FTUs huggingface dataset:
Correction of machining operations with the Total Inertial Steering

The Total Inertial Steering approach proposed in this paper can perform an optimum correction of the geometric deviations of the manufactured part with respect to its digital model, from the measured points on its surfaces. In the case of production by machine tool numerical control, there exist a link between the tool offsets and deviations of measured points. An incidence matrix which represents this link is obtained. In most cases, this matrix is not square and therefore not invertible, because there are more measured points as correctors to adjust. The Gauss pseudo-inverse is used to calculate the values of corrections to be made to compensate for measured deviations. Tolerances associated with the surfaces must also be taken into account in the incidence matrix. However, when the same cutting tool machine two surfaces with different point values, the resulting solution favors the one with the highest number of points, at the expense of the other surface which can remain not conform towards its tolerance. This paper proposes a strategy to rebalance the correction surfaces, and this regardless of the number of points and tolerance of each surfaces. A relatively simple tutorial example is given in the paper to enable tracking calculations.
1 Supporting information for Topology of the microsomal glycerol-3-phosphate acyltransferase Gpt 2 p / Gat 1 p of Saccharomyces cerevisiae

Supporting information for Topology of the microsomal glycerol-3-phosphate acyltransferase Gpt2p/Gat1p of Saccharomyces cerevisiae Martin Pagac, Hector M. Vazquez, Arlette Bochud, Carole Roubaty, Cécile Knöpfli, Christine Vionnet, and Andreas Conzelmann Department of Biology, University of Fribourg, CH-1700 Fribourg, Switzerland; Present address: College of Pharmacy, University of Hawaii, Hilo, USA These authors contributed equally to the work. Correspondence: andreas.conzelmann@unifr.ch, Phone ++41263008631, Fax ++41263009735, Chemin du musée 10, CH-1700, Fribourg, Switzerland
Fuzzy Control of Multivariable Processes

Most processes in industry are complex mul-tivariable systems with nonlinear and time-varying dynamics. These processes are often diicult to model. However, often much expert knowledge and process data is available. Fuzzy modeling and control techniques can eeciently integrate this information. However, most of the systems considered in literature are of low-order and SISO or MISO systems. For MIMO systems, complications occur because the size of the rule bases and computational load increases dramatically for higher order systems. Within the FAMIMO ESPRIT project see acknowledgements , new algorithms are being developed for the indentiication and control of MIMO systems. The main research items are: MIMO model identiication Fuzzy heterogeneous control Pseudo inversion of fuzzy models Fuzzy adaptive control Model based predictive control Methods for stability analysis Development of software tools New developments from our group and the partners in FAMIMO will be presented. In Delft, a software toolbox for MIMO Takagi-Sugeno 44 fuzzy model identiication is developed 11. Two methods for MBPC using these models are investigated. Namely, local linearized control 3 and a Branch & Bound algorithm. Both methods are incorporated in an internal model control IMC 2 scheme. Two benchmarks are used to compare the developed methods : Wastewater treatment of a paper factory Direct injection engine Acknowledgements: This work has been done
Indices of low-grade chronic inflammation in polycystic ovary syndrome and the beneficial effect of metformin.

BACKGROUND Women with polycystic ovary syndrome (PCOS) have an increased prevalence of insulin resistance (IR) and related disorders. Elevated serum levels of cellular adhesion molecules (CAMs) reflect low-grade chronic inflammation and have been associated with several insulin-resistant states. The objective of this study is to investigate whether soluble inflammatory markers [soluble intercellular adhesion molecule-1 (sICAM-1), soluble endothelial leukocyte adhesion molecule-1 (sE-selectin), soluble vascular cell adhesion molecule-1 (sVCAM-1) and C-reactive protein (CRP)] are altered in PCOS and to further elucidate the effect of metformin treatment on their levels. METHODS Two young populations were studied [62 women with PCOS and 45 normal women of similar age, BMI and waist-to-hip ratio (WHR)]. Plasma levels of sICAM-1, sVCAM-1, sE-selectin and high-sensitivity CRP (hsCRP) were measured in both groups. Additionally, the effect of metformin on these molecules was investigated in 22 women with PCOS who accepted to metformin protocol (1700 mg daily for a 6-month period). RESULTS In the total population studied, plasma levels of hsCRP (mg/l), sICAM-1 (ng/ml) and sE-selectin (ng/ml) were higher in the PCOS group compared with those in controls (hsCRP 1.31 +/- 0.22 versus 0.92 +/- 0.27, P = 0.014, sICAM-1 301.21 +/- 24.80 versus 209.86 +/- 17.05, P = 0.025, sE-selectin 57.37 +/- 4.08 versus 45.67 +/- 4.62, P = 0.045, respectively). sVCAM-1 (ng/ml) did not differ statistically among the two groups (P = 0.896). A significant reduction in hsCRP and sVCAM-1 was achieved after 6 months of metformin administration: PCOS pretreatment hsCRP 1.92 +/- 0.60 versus PCOS post-treatment hsCRP 0.52 +/- 0.26, P = 0.005; PCOS pretreatment sVCAM-1 668.09 +/- 98.38 versus PCOS post-treatment sVCAM-1 365.82 +/- 99.77, P = 0.039. CONCLUSION These findings imply the presence of chronic inflammation in women with PCOS. Metformin decreases the levels of plasma inflammatory indices. Further investigation is required to determine whether these findings may prove to be of clinical significance for PCOS patients.
Evaluation of the cost-effectiveness of root canal treatment using conventional approaches versus replacement with an implant.

AIM To evaluate the cost-effectiveness of root canal treatment for a maxillary incisor tooth with a pulp infection, in comparison with extraction and replacement with a bridge, denture or implant supported restoration. METHODOLOGY A Markov model was built to simulate the lifetime path of restorations placed on the maxillary incisor following the initial treatment decision. It was assumed that the goal of treatment was the preservation of a fixed platform support for a crown without involving the adjacent teeth. Consequently, the model estimates the lifetime costs and the total longevity of tooth and implant supported crowns at the maxillary incisor site. The model considers the initial treatment decisions, and the various subsequent treatment decisions that might be taken if initial restorations fail. RESULTS Root canal treatment extended the life of the tooth at an additional cost of pound5-8 per year of tooth life. Provision of orthograde re-treatment, if the root canal treatment fails returns further extension of the expected life of the tooth at a cost of pound12-15 per year. Surgical re-treatment is not cost-effective; it is cheaper, per year, to extend the life of the crown by replacement with a single implant restoration if orthograde endodontic treatment fails. CONCLUSION Modelling the available clinical and cost data indicates that, root canal treatment is highly cost-effective as a first line intervention. Orthograde re-treatment is also cost-effective, if a root treatment subsequently fails, but surgical re-treatment is not. Implants may have a role as a third line intervention if re-treatment fails.
hemical composition of essential oils of leaves , flowers and fruits f

Hortia oreadica Groppo, Kallunki & Pirani, Rutaceae, known as “para-tudo”, “quina”, and “quina-docampo”, is used in traditional medicine locally to treat stomach pain and fevers. The aims of this study were: analyze the chemical composition of essential oils from leaves, flowers and fruits of H. oreadica and verify the seasonal variation of the chemical components of essential oils from leaves. The essential
A new foreperiod effect on single-trial phase coherence. Part I: existence and relevance

Expecting events in time leads to more efficient behavior. A remarkable early finding in the study of temporal expectancy is the foreperiod effect on reaction times; i.e., the fact that the time period between a warning signal and an impendent stimuli, to which subjects are instructed to respond as quickly as possible, influences reaction times. Recently it has been shown that the phase of oscillatory activity preceding stimulus presentation is related to behavior. Here we connect both of these findings by reporting a novel foreperiod effect on the inter-trial phase coherence triggered by a stimulus to which subjects do not respond. Until now, inter-trial phase coherence has been used to describe a regularity in the phases of groups of trials. We propose a single-trial measure of inter-trial phase coherence and prove its soundness. Equipped with this measure, and using a multivariate decoding method, we demonstrate that the foreperiod duration modulates single-trial phase coherence. In principle, this modulation could be an artifact due to the decoding method used to detect it. We show that this is not the case, since the modulation can also be observed with a very simple averaging method. Although real, the single-trial modulation of inter-trial phase coherence by the foreperiod duration could just reflect a nuisance in our data. We argue against this possibility by showing that the strength of the modulation correlates with subjects’ behavioral measures, both error rates and mean-reaction times. We anticipate that the new foreperiod effect on inter-trial phase coherence, and the decoding method used here to detect it, will be important tools to understand cognition at the single-trial level. In Part II of this manuscript, we support this claim, by showing that attention modulates the strength of the new foreperiod effect in a trial-by-trial basis.
Optimal load distribution of cluster head in fault-tolerant wireless sensor network

Wireless sensor network (WSN) is undoubtedly an area of sophisticated research work. The credibility of this astonishing system may be affected by faults due to harsh and hazardous natural calamities from time to time. A WSN that is not ready to deal with such challenging situations may suffer a reduction in overall lifetime or may lead to dire consequences in critical application context. So fault tolerance technique is one of the most vital approach to renew the default condition. In this paper we propose a method to support fault tolerant by function distribution. Initially, the entire network is considered as a set of clusters. One cluster head is selected from each cluster and later some of its functions are distributed between its two neighbours. This is achieved in such a way that the energy consumption of the network gets minimised. Through simulation we have established that our proposed schema reduces the cluster head load and prolong the network life span.
The Concentration of Iodine in Perigastric Adipose Tissue: A Novel Index for the Assessment of Serosal Invasion in Patients with Gastric Cancer after Neoadjuvant Chemotherapy

Objective: This study aims to explore the association between iodine concentration (IC) in perigastric adipose tissue (PAT), quantified by dual-energy computed tomography (DECT) and serosal invasion (SI) in patients with gastric cancer post-neoadjuvant chemotherapy (NAC). Methods: Forty-three patients with T4-staged gastric cancer were enrolled. IC and standardized IC in PAT (ICPAT and SICPAT) were quantified by DECT pre and post NAC. A postoperative pathologic examination was performed to stage gastric cancer. Results: After NAC, a total of 43 participants were assigned to group A with 13 patients and group B with 30 patients according to the results of the postoperative pathologic examination. The accuracy of conventional CT in identifying SI was 74.42%. Differences of variations between pre- and post- NAC ICPAT, SICPAT, ∆ICPAT, and ∆SICPAT were observed respectively (p < 0.05). Intragroup ICPAT and SICPAT also changed significantly after NAC (p < 0.05). The area under the ROC curve was 0.929, with the threshold of ∆SICPAT reaching 0.095. The sensitivity, specificity, and accuracy of SICPAT in identifying post-NAC SI were 92.30, 86.70, and 88.37% respectively. Moreover, the 2 measurements in the same patient maintain a high level of consistency. Conclusion: These results showed that SICPAT is a reliable index for identifying post-NAC SI.
Identification of dendritic cells, B cell and T cell subsets in Tasmanian devil lymphoid tissue; evidence for poor immune cell infiltration into devil facial tumors

The Tasmanian devil is under threat of extinction due to the transmissible devil facial tumor disease (DFTD). This fatal tumor is an allograft that does not induce an immune response, raising questions about the activity of Tasmanian devil immune cells. T and B cell analysis has been limited by a lack of antibodies, hence the need to produce such reagents. Amino acid sequence analysis revealed that CD4, CD8, IgM, and IgG were closely related to other marsupials. Monoclonal antibodies were produced against CD4, CD8, IgM, and IgG by generating bacterial fusion proteins. These, and commercial antibodies against CD1a and CD83, identified T cells, B cells and dendritic cells by immunohistochemistry. CD4+ and CD8+ T cells were identified in pouch young thymus, adult lymph nodes, spleen, bronchus‐ and gut‐associated lymphoid tissue. Their anatomical distribution was characteristic of mammalian lymphoid tissues with more CD4+ than CD8+ cells in lymph nodes and splenic white pulp. IgM+ and IgG+ B cells were identified in adult lymph nodes, spleen, bronchus‐associated lymphoid tissue and gut‐associated lymphoid tissue, with more IgM+ than IgG+ cells. Dendritic cells were identified in lymph node, spleen and skin. This distribution is consistent with eutherian mammals and other marsupials, indicating they have the immune cell subsets for an anti‐tumor immunity. Devil facial tumor disease tumors contained more CD8+ than CD4+ cells, but in low numbers. There were also low numbers of CD1a+ and MHC class II+ cells, but no CD83+ IgM+ or IgG+ B cells, consistent with poor immune cell infiltration. Anat Rec, 297:925–938, 2014. © 2014 The Authors. The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology Published by Wiley Periodicals, Inc.
SOI digital accelerometer based on pull-in time configuration

We aim to present the principle, design, fabrication and measurement results of a quasi digital accelerometer fabricated on thin silicon-on-insulator (SOI) substrate. The presented device features quasi-digital output, therefore eliminating the need for analogue signal conditioning. The accelerometer can be directly interfaced to digital electronic circuitry. The measurements showed a pull-in voltage of 2.7V and a pull-in time from 0 to 1G to be 3. 2µs.
On the Persistence of Tool-Based Compatibility Effects

Using tools, such as simple levers, makes specific demands on the motor system. Two related performance decrements have been reported: The costs that arise when required tool movements and movements of the operating hand are spatially incompatible (hand-tool compatibility), and the costs that arise when relevant stimuli and tool movements are spatially incompatible (stimulus-tool compatibility). We performed two experiments to test the boundary conditions of both effects. Experiment 1 revealed a strong hand-tool compatibility effect despite visual occlusion of the hand and instructions to ignore hand movements. Experiment 2 revealed influences of stimulus-tool compatibility despite instructions to ignore the tool and to pay attention to the operating hand alone. These results suggest that lever movements of the type studied here become automatically represented and constrain motor performance.
Intraperitoneal Injection of Multiplacentas Pooled Cells Treatment on a Mouse Model with Aplastic Anemia

Coinfusion of hematopoietic and mesenchymal stem cells is more effective than hematopoietic stem cell transplantation alone. It is necessary to explore a safe and routine mixed stem cell intraperitoneal transplantation method. Multiplacentas pooled cells were intraperitoneally injected into a radiation- and immunity-induced mouse aplastic anemia model with single time. Then, mouse survival time, peripheral blood hemoglobin count, bone marrow architecture, and donor cell engraftment were assessed. The recipient mouse exhibited donor cell engraftment in both bone marrow and peripheral blood. Survival time and peripheral blood hemoglobin count increased in placenta pooled cells treated mice, compared with model-only controls (P = 0.048 and P = 0.000, resp.). However, placentas pooled cells failed to cause a significant decrease in bone marrow pimelosis area (P = 0.357). Intraperitoneally transplanted multiplacentas pooled cells can survive and engraft into a host body through blood circulation, which can increase the life span of an aplastic anemia model mice, and delay but not abrogate the development of aplastic anemia. Furthermore, they appear to play a role in increasing peripheral blood hemoglobin level response for increasing the life span of aplastic anemia model mice.
Impact of a Rapid Blood Culture Assay for Gram-Positive Identification and Detection of Resistance Markers in a Pediatric Hospital.

CONTEXT Molecular diagnostics allow for rapid identification and detection of resistance markers of bloodstream infection, with a potential for accelerated antimicrobial optimization and improved patient outcomes. Although the impact of rapid diagnosis has been reported, studies in pediatric patients are scarce. OBJECTIVE To determine the impact of a molecular blood-culture assay that identifies a broad-spectrum of pathogens and resistance markers in pediatric patients with gram-positive bloodstream infections. DESIGN Data on the time to antimicrobial optimization, the length of hospitalization, and the hospital cost following implementation of a rapid assay were prospectively collected and compared with corresponding preimplementation data. RESULTS There were 440 episodes from 383 patients included, 221 preimplementation episodes and 219 postimplementation episodes. Overall time to antimicrobial optimization was shortened by 12.5 hours (P = .006), 11.9 hours (P = .005) for bloodstream infections of Staphylococcus aureus specifically. Duration of antibiotics for those with probable blood-culture contamination with coagulase-negative staphylococci was reduced by 36.9 hours (P < .001). Median length of stay for patients admitted to general pediatric units was 1.5 days shorter (P = .04), and median hospital cost was $3757 (P = .03) less after implementation. For S aureus bloodstream infections, median length of stay and hospital cost were decreased by 5.6 days (P = .01) and $13,341 (P = .03), respectively. CONCLUSIONS Implementation of molecular assay for the detection of gram-positive pathogens and resistance markers significantly reduced time to identification and resistance detection, resulting in accelerated optimization of therapy, shorter length of stay, and decreased health care cost.
2-Iodo-N-isopropyl-5-methoxybenzamide as a highly reactive and environmentally benign catalyst for alcohol oxidation

Several N-isopropyliodobenzamides were evaluated as catalysts for the oxidation of benzhydrol to benzophenone in the presence of Oxone® (2KHSO5·KHSO4·K2SO4) as a co-oxidant at room temperature. A study on the substituent effect of the benzene ring of N-isopropyl-2-iodobenzamide on the oxidation revealed that its reactivity increased in the following order of substitution: 5-NO2 < 5-CO2Me, 3-OMe < 5-OAc < 5-Cl < H, 4-OMe < 5-Me < 5-OMe. The oxidation of various benzylic and aliphatic alcohols using a catalytic amount of the most reactive 5-methoxy derivative successfully resulted in moderate to excellent yields of the corresponding carbonyl compounds. The high reactivity of the 5-methoxy derivative at room temperature is a result of the rapid generation of the pentavalent species from the trivalent species during the reaction. 5-Methoxy-2-iodobenzamide would be an efficient and environmentally benign catalyst for the oxidation of alcohols, especially benzylic alcohols.
Participatory design for technological disruption within the agricultural sector

Agricultural adoption of innovation has traditionally been described as slow to diffuse. This paper therefore describes a case study grounded in PD to address a disruptive technology/system within the livestock industry. Results of the process were positive, as active engagement of stakeholders returned rich data. The contribution of the work is also presented as grounds for further design research in the livestock industry.
RFID : Recent prospectus and commercial applications

This paper portrays recent trends in Radio Frequency Identification (RFID) systems and its commercial relevance. RFID is one of the most researched and rapidly emerging technologies. With the recent technological advancements at International level, it is finding its application in various areas and has a bright future scope. Exemplary future applications and systems based on RFID and other technologies integrated with RFID are proposed in this paper. We have discussed about applications, problems being faced by RFID systems & their limitations in other fields in the current era The commercial scope in the field of RFID manufacturing and research has been discussed along with its business prospectus. We have discussed about the hardware and software limitations that may be restricting or preventing its usage or feasibility in some fields or areas. We tried to depict some of the future enhancements that may be possible.
Employability: The missing voice: How student and graduate views could be used to develop future higher education policy and inform curricula

The student voice is currently absent from the employability agenda for higher education in the UK. A government-led neo-liberal model of employability, claiming what employers want when employing graduates, has been uncritically adopted by many universities in the UK to inform higher education strategy and policy. Many undergraduates and graduates perceive this employability model as incongruent and disingenuous to their experiences in gaining and sustaining work. The dominant employability discourse masks inequalities in the contemporary labour market. In developing policies for the future of higher education, British government departments should recognise the student lens by researching students’ qualitative experiences and reflections of teaching, learning and work. Students should be a collaborative part of future planning, and their voices should be continuously informing higher education practice. Student and graduate views can be used to inform higher education curricula and develop meaningful future policy relating to higher education.