Miracle-dz/UniFAR-FTUs huggingface dataset:
In Situ Simulation in Continuing Education for the Health Care Professions: A Systematic Review

Introduction: Education in the health sciences increasingly relies on simulation‐based training strategies to provide safe, structured, engaging, and effective practice opportunities. While this frequently occurs within a simulation center, in situ simulations occur within an actual clinical environment. This blending of learning and work environments may provide a powerful method for continuing education. However, as this is a relatively new strategy, best practices for the design and delivery of in situ learning experiences have yet to be established. This article provides a systematic review of the in situ simulation literature and compares the state of the science and practice against principles of effective education and training design, delivery, and evaluation. Methods: A total of 3190 articles were identified using academic databases and screened for descriptive accounts or studies of in situ simulation programs. Of these, 29 full articles were retrieved and coded using a standard data extraction protocol (kappa = 0.90). Results: In situ simulations have been applied to foster individual, team, unit, and organizational learning across several clinical and nonclinical areas. Approaches to design, delivery, and evaluation of the simulations were highly variable across studies. The overall quality of in situ simulation studies is low. A positive impact of in situ simulation on learning and organizational performance has been demonstrated in a small number of studies. Discussion: The evidence surrounding in situ simulation efficacy is still emerging, but the existing research is promising. Practical program planning strategies are evolving to meet the complexity of a novel learning activity that engages providers in their actual work environment.
A Domain Specific Modeling Language for REA

The Resource-Event-Agent (REA) ontology has its roots in the accounting discipline and was originally developed as a reference framework to conceptualize economic phenomena in an enterprise. In its proposal in 1982, McCarthy already had the vision to facilitate the design of data structures of accounting information systems by means of REA [1]. Since this time the REA model has been further extended and evolved into a domain ontology [2]. All REA concepts are based on well established concepts of the literature in economic theory which is certainly one of the strengths of REA. However, REA has no dedicated representation format and, consequently, no graphical syntax. Thus, users may struggle when describing the REA models leading to the impression that REA is a rather heavy-weight approach. McCarthy feels (as he expressed during our joint work in standardization activities) that a dedicated graphical syntax such as it exists for e3-value may help in overcoming this problem and may lead to a much more significant adoption of REA. Accordingly, we have started the endeavor of developing a domain specific modeling language for REA. 1 A domain-specific language (DSL) is a small, usually declarative language. It offers expressive power through appropriate notations and abstractions focused on – and usually restricted to – a particular problem domain [3]. Besides textual DSLs, we see an increasing interest in domain-specific modeling languages [4, 5]. According to [3] the benefits of a DSL approach are manifold: They allow solutions to be expressed at the level of abstraction of the problem domain. As a matter of fact, domain experts themselves can understand, validate and often modify DSL programs/models. The DSL programs/models are concise and self documenting to a large extent. They enhance productivity, reliability and maintainability. DSLs allow for validation and optimization at the domain level. When developing our REA-DSL we followed methodological steps that have been suggested by Strembeck and Zdun for the systematic development of domain specific languages [6]. Amongst other variants, they describe the development process for extracting a DSL from an existing system, which is appropriate
High Density Lipoprotein Cholesterol and the Risk of All-Cause Mortality among U.S. Veterans.

BACKGROUND AND OBJECTIVES The relationship between HDL cholesterol and all-cause mortality in patients with kidney disease is not clear. We sought to characterize the relationship of HDL cholesterol and risk of death and examine the association by eGFR levels. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS We built a cohort of 1,764,986 men who were United States veterans with at least one eGFR between October of 2003 and September of 2004 and followed them until September of 2013 or death. RESULTS Patients with low HDL cholesterol and low eGFR had a higher burden of comorbid illnesses. Over a median of 9.1 years (interquartile range, 7.7-9.4 years), 26,247 (40.1%), 109,222 (32.3%), 152,625 (29.2%), 113,785 (28.5%), and 139,803 (31.8%) participants with HDL cholesterol ≤25, >25 to <34, ≥34 to ≤42, >42 to <50, and ≥50 mg/dl died. In adjusted survival models, compared with the referent group of patients with low HDL cholesterol (≤25 mg/dl), intermediate HDL cholesterol levels (>25 to <34, ≥34 to ≤42, and >42 to <50 mg/dl) were associated with lower risk of death across all levels of eGFR. The lower risk was partially abrogated in those with high HDL cholesterol (≥50 mg/dl), and the risk of death was similar to the referent category among those with eGFR<30 or ≥90 ml/min per 1.73 m2. Analysis by HDL cholesterol deciles and spline analyses suggest that the relationship between HDL cholesterol and death follows a U-shaped curve. There was a significant interaction between eGFR and HDL cholesterol in that lower eGFR attenuated the salutary association of HDL cholesterol and risk of death (P for interaction <0.01). Presence of coronary artery disease attenuated the lower risk of high HDL cholesterol and all-cause mortality in those with eGFR≥60 ml/min per 1.73 m2 (P for interaction <0.05). CONCLUSIONS Our results show a U-shaped relationship between HDL cholesterol and risk of all-cause mortality across all eGFR categories. The risk is modified by eGFR and cardiovascular disease.
Technical comparison between a gas-insulated line and a traditional three-bundled OHL for a 400 kV, 200 km connection

Aiming to explore the applicability of Gas-Insulated Lines (GILs) over long distances, in this paper we perform a technical comparison between a GIL and a three-conductor bundled, traditional overhead line (OHL), for a 400 kV, 200 km long connection. The technical comparison is based upon transmission capacity and power losses. We derive the transmission capacity of the two systems from the relevant loadability curves, for the selected line length L=200 km. For this length, OHLs loadability curves are normally determined by the voltage drop limit, ΔVmax (i.e. the maximum voltage drop allowed across the line), whereas the GIL loadability can be determined - according to the selected GIL parameters - by the thermal limit. In addition to power losses in the conductors, Gil losses include losses in the enclosures. The results point out remarkable advantages for the GIL solution.
Bioavailability of Magnesium Salts – A Review

Background: Magnesium supplementation is of value in several different medical disorders. Several kinds of Mg-salts are commercially available. Purpose: This review evaluates their bioavailability criteria such as solubility, urinary excretion, and plasma levels of magnesium from studies of different Mg-salts. Conclusion: Although methodology differences were large, the results consistently demonstrate a better bioavailability for Mg-citrate.
Survey on Location Privacy in Location Based Services

: Now a day’s use of smart phones and tablets is drastically increased. Various services are available to us by just one click on our mobile devices one such a service is Location Based service . User send the query to service provider to get services like nearby restaurant, friends in vicinity, share his/her location with other friends,rendezvous point to meetetc . But getting a desired service is not enough as location privacy is always one of the greatest concerns of the user. There are various threat to privacy when user shares his/her location. The information can be misused for stalking, home invasion, political loss etc. Various methods were introduced in past to deal with privacy concerns. This paper explores different methods to deal with privacy concerns.
Insiders’ Views of New Literacies, Schooling, and the Purpose of Education: “We Should be Teaching Them more Important Things”

Given that most preservice teachers have grown up in a technological world, it is commonly accepted that they will bring their new literacies knowledge and skills into their future classrooms. However, little is actually known about preservice teachers’ perceptions of the place of new literacies in elementary schools. Therefore, the purpose of this paper was to investigate preservice elementary teachers’ perceptions of the need to support or teach new literacies in their future classrooms. Using survey design, descriptive analysis, and thematic analysis the following three findings were identified: (a) the participants of this study were insiders, (b) the participants favored teaching traditional, school-based literacies, and (c) the participants assumed that the purpose of education was to do well in school. The findings suggest that rather than assume preservice teachers will simply bring their new literacies practices into schools and help their future students engage in the multiple literacies needed for success in and out-of-school, teacher educators must explicitly prepare them to do so.
On a robust real-time H∞ controller design for an electrical drive

In this paper, a robust H∞ controller is designed and applied to a DC motor, as an electrical drive. In H∞ mixed sensitivity framework, several satisfying results, mainly in terms of tracking trajectories, control signal moderation, disturbance rejection as well as robustness stability in the case of neglected dynamics uncertainty, were obtained using a four-block criterion design structure. The proposed H∞ controller algorithm was successfully implemented and tested in the real-time framework using a multi-function data acquisition PCI-1710 board.
The Three Clades of the Telomere-Associated TLO Gene Family of Candida albicans Have Different Splicing, Localization, and Expression Features

ABSTRACT Candida albicans grows within a wide range of host niches, and this adaptability enhances its success as a commensal and as a pathogen. The telomere-associated TLO gene family underwent a recent expansion from one or two copies in other CUG clade members to 14 expressed copies in C. albicans. This correlates with increased virulence and clinical prevalence relative to those of other Candida clade species. The 14 expressed TLO gene family members have a conserved Med2 domain at the N terminus, suggesting a role in general transcription. The C-terminal half is more divergent, distinguishing three clades: clade α and clade β have no introns and encode proteins that localize primarily to the nucleus; clade γ sometimes undergoes splicing, and the gene products localize within the mitochondria as well as the nuclei. Additionally, TLOα genes are generally expressed at much higher levels than are TLOγ genes. We propose that expansion of the TLO gene family and the predicted role of Tlo proteins in transcription regulation provide C. albicans with the ability to adapt rapidly to the broad range of different environmental niches within the human host.
A Formal Model for Metacognitive Reasoning in Intelligent Systems

This paper presents a formal model of metacognitive reasoning in intelligent systems IS. The proposed model was named fM2 and uses predicate logic to represent a cycle of reasoning about failures generated in reasoning tasks in an IS. fM2 has mechanisms such as introspective monitoring and meta-level control to perform metacognitive reasoning. fM2 was implemented and validated on an intelligent tutoring system named FUNPRO. The performance metrics of FUNPRO indicate the capacity of fM2 to drastically decrease the reasoning failures produced in the recommendations of FUNPRO. Thus, this paper demonstrates the efficacy of fM2 as a valid tool to improve the performance of the reasoning processes of IS.
Effect of dose of Brucella abortus strain 19 in yearling heifers on the relative risk of developing brucellosis from challenge exposure with strain 2308.

Yearling heifers were given SC injections of 10(8) (n = 40), 10(9) (n = 44), or 10(10) (n = 44) colony-forming units of Brucella abortus strain 19 (S19). The proportion of heifers with positive serologic test results at 1 month following vaccination increased as the dose of S19 increased. These proportions decreased with time, and all heifers had negative card, rivanol, and complement fixation test results within 4 months. Positive ELISA results persisted beyond 4 months in all three S19 dose groups; however, all heifers were ELISA-negative within 9 months after vaccination. Comparable lymphocyte transformation activity was stimulated by S19 dose of 10(9) or 10(10) and approximately half of the heifers in both groups had a positive stimulation index at 9 months. Immunity of the pregnant heifers was challenged 9 months after vaccination with 10(7) B abortus strain 2308 as follows: diluent controls (n = 69); 10(8) B abortus S19 (n = 40); 10(9) B abortus S19 (n = 39); and 10(10) B abortus S19 (n = 39). Tissue specimens from heifers were obtained at parturition and necropsy for culturing of B abortus. The proportion of heifers that developed brucellosis, ie, had positive culture results, increased as gestation days at challenge exposure increased. The effect of gestational age was controlled in the analysis using logistic regression. The relative risk of brucellosis was reduced to 0.38, 0.15, and 0.06 for B abortus S19 doses of 10(8), 10(9), and 10(10), respectively, compared with diluent controls at 1. (ABSTRACT TRUNCATED AT 250 WORDS)
Effects of annealing on Sn whisker formation: Role of Cu alloy seed layer

To cope with the miniaturization trend in the electronic packaging, the parts of components are getting smaller and closer, so that the risk of shorting by Sn whiskers is becoming much greater. Many works have been done on the investigation of Sn whisker growth as well as on its mitigations. Intermetallic compound (IMC) formation is believed to be one of the major driving forces. One might consider that the grain size of the Cu as a diffusion species plays a role in IMC formation. Therefore, this study investigates the effects of the Cu alloy thin film as a seed layer and annealing on Sn whisker formation. In order to study those effects, Cu thin films, added with minor concentration of Ru with various thicknesses prepared by radio magnetron sputtering, were introduced as the seed layers. Pure Cu thin films with the same thicknesses were also introduced for comparisons. Annealing of the samples was also carried out prior to Sn electroplating. To accelerate Sn whisker growth, all of samples were aged at 60°C for 20 hr. Their effects in term of whisker density have been studied.
Modeling the Spectral Luminescence Emission of Silicon Solar Cells and Wafers

A generalized expression for the theoretical description of luminescence spectra of silicon solar cells and wafers is outlined. Models of the spectral luminescence emission, which can be found in the literature, are reviewed and compared with spectrally resolved photoluminescence measurements carried out on specially prepared samples. These models describe the spectrum of samples with either two planar or two rough (lambertian reflecting) surfaces. Good qualitative agreement is shown. Moreover, we introduce a new model which is valid for samples with any configuration of planar and textured surfaces and also takes free carrier absorption into account. The accuracy of the model is experimentally confirmed by a comparison to an electroluminescence spectrum of an industrial silicon solar cell.
A modified cup-method for lightweight and highly permeable materials

With an increasing interest for dynamic hygrothermal calculation models for short time periods, there is a need for uncomplicated and reliable methods to determine the moisture properties for materials used in the indoor environment. The traditional cup-method is commonly used for building materials to determine the water vapor permeability. When used on lightweight and highly permeable materials, the unidentified inner surface resistance of the cup-method will be problematic and fastening the sample to the cup can be troublesome. To address these problems, we have developed a modified cup-method based on standard laboratory crimp cap vials to determine the water vapor resistance for lightweight and highly permeable materials, such as textiles and paper. This modified cup-method together with a validation is presented in the paper. (Less)
Mutations in riboflavin transporter present with severe sensory loss and deafness in childhood

Introduction: We have identified a large consanguineous Lebanese family with 5 individuals with severe childhood‐onset recessive sensory loss associated with deafness and variable optic atrophy. Methods: Autozygosity mapping was performed in all affected individuals, followed by whole‐exome sequencing (WES) in 2 individuals. Results: WES identified a homozygous missense mutation (c.916G>A, p.G306R) in the cerebral riboflavin transporter SLC52A2, recently shown to cause Brown‐Vialetto‐Van‐Laere syndrome (BVVLS), which is considered primarily a motor neuronopathy. Our patients have a phenotype distinct from BVVLS, characterized by severe progressive sensory loss mainly affecting vibration and proprioception that evolves to include sensorineural hearing loss in childhood, variable degrees of optic atrophy, and marked upper extremity weakness and atrophy. Treatment of 3 patients with 400 mg/day riboflavin over 3 months produced definite clinical improvement. Conclusions: Mutations in SLC52A2 result in a recognizable phenotype distinct from BVVLS. Early recognition of this disorder is critical, given its potential treatability. Muscle Nerve 50: 775–779, 2014
Determining Arsenic Distribution in Urban Soils: A Comparison with Nonurban Soils

There are many challenges in the determination of arsenic background concentrations in soils. However, these challenges are magnified when those determinations are carried out on urban soils. Irrespective of this, it is important to correctly identify and understand the extent of pollution in order to provide efficient preventative, remedial actions and cost-effective management of contaminated areas. This review paper discusses the factors that make the determination of arsenic background concentrations in urban areas different from similar determinations in nonurban areas. It also proposes solutions, where applicable, that are based on experience in determining arsenic background concentrations in both urban and nonurban areas in Florida, and from other studies in the literature. Urban soils are considerably different from nonurban areas because they have significant human disturbance, making them more difficult to study. They are characterized by high spatial and temporal variability, compaction, and modified chemical and physical characteristics. These differences have to be addressed during site selection, sample collection, and statistical analyses when determining arsenic distribution.
Effect of Coagulating Agents on Lignin and Oligosaccharide Contents in Pre-Hydrolysis Liquor Obtained in the Production of Dissolving Pulp from Poplar Residual Slabs

Pre-hydrolysis is an important step in the poplar residual slab dissolving pulp production process, as it aids in removing as much hemicellulose as possible from the cellulose fibers. In the pre-hydrolysis process, a portion of lignin also dissolves, along with the hemicelluloses. The presence of lignin in prehydrolysis liquor (PHL) is detrimental to the separation of xylo-oligosaccharide from the prehydrolysis liquor. This study researched lignin removal from PHL with three coagulating agents, namely aluminum sulfate (alum), polyaluminum chloride (PAC), and polydiallyldimethyl ammonium chloride (pDADMAC). It was found that the removal of lignin increased as the dosage of the alum, PAC, and pDADMAC increased. Additionally, the highest retention of xylo-oligosaccharide in the PHL occurred at dosages of 120 mg/L for alum and 160 mg/L for PAC and pDADMAC. The contents of the other oligosaccharides in PHL fluctuated irregularly with increasing dosages of the alum, PAC, and pDADMAC.
Increased WNT 6 expression in tumor cells predicts unfavorable survival in esophageal squamous cell carcinoma patients

WNT proteins are a family of secreted, cysteine-rich proteins containing 19 members. Signaling through WNT proteins is reported to be involved in carcinogenesis and cancer progression of gastrointestinal tumors, such as gastric cancer and colon cancer. The expression status of WNT6 in ESCCs and their clinico-prognostic significances remain to be elucidated. In this study, One-hundred and thirty-six patients with ESCC were explored. Paraffin-embedded tumor sections were stained with WNT6 antibody. The correlations between WNT6 expression and survival parameters were analyzed. The overall frequency of WNT6 over-expression was 50.7% (69/136) of advanced EC patients. For DMS and OS, over-expression of WNT6 remained the independent factor for worse prognosis (hazard ratio (HR), 2.425; 95% CI, 1.631-3.605; P < 0.001 for OS and HR, 2.238; 95% CI, 1.507-3.323; P < 0.001 for DMS, respectively). To conclude, our results support the concept that WNT6 may play a role in tumor progression. WNT6 over-expression inversely correlates with the poor long-term survival in ESCC patients. WNT6 can be considered as a predictor for recurrence.
Dry Matter Yield and Nutritional Characteristics of Elephant-Grass Genotypes

In the elephant-grass germplasm, there are genotypes that show a large genetic variability differentiated by morphological, reproductive, agronomic and biochemical characteristics. As such, there is a selection of new and more adapted elephant-grass genotypes, with greater productivity and nutritional quality, which can cause an increase in the forage offer, especially during the dry season. Thus, this work aimed at evaluating, throughout two years, the productive performance and nutritional value of 53 elephant-grass genotypes to produce forage in the edaphoclimatic conditions in Campos dos Goytacazes city, Rio de Janeiro State, Brazil. The experiment was composed of 53 elephant-grass accessions from the Banco de Germoplasma da Embrapa Gado de Leite (Germplasm Bank of Embrapa Gado de Leite), located in Coronel Pacheco city, Minas Gerais state, Brazil. It was applied the randomized complete block experimental design with 53 accessions two replications. Cuttings were performed every two months, throughout two years, totaling ten cuttings. The morpho-agronomic and bromatological characteristics were assessed, and the statistical analyses were carried out applying the Computational Applicative in Genetic and Statistics, Genes. Results indicated that there is a wide genetic variability among the elephant-grass genotypes concerning the characteristics under study. The Mineiro, Guaçu IZ-2 and Acesso 91 – EMBRAPA genotypes were those that showed to be superior to all traits evaluated simultaneously. They proved to be the most productive and with higher nutritional quality. Therefore, they are the most indicated to produce forage in the edaphoclimatic conditions of Campos dos Goytacazes city, Rio de Janeiro State.