Miracle-dz/UniFAR-FTUs huggingface dataset:
XML und SOA als Wegbereiter für Sensornetze in der Praxis

Martin Lipphardt ist wissenschaftlicher Mitarbeiter am Institut für Telematik der Universität zu Lübeck. Er absolviert sein Studium der Informatik mit Nebenfach Bioinformatik und Biomathematik an der Universität zu Lübeck. Während seines erhielt er ein DAAD Stipendium an der National Chiao Tung University, Taiwan. Am Institut für Telematik forschte er im Rahmen des MarathonNet-Projektes an mobilen Sensornetzen in der praktischen Anwendung. Im Rahmen des DFG-Projektes Aesop’s Tale befasst er sich momentan mit service-orientierten Architekturen für Sensornetze.
Preliminary Evidence for Ethnic Differences in Primary Hyperoxaluria Type 1 Genotype

Background: Primary hyperoxaluria type 1 (PH1) is caused by a deficiency of peroxisomal alanine:glyoxylate aminotransferase (AGT). In about one third of patients, enzymatically active AGT is synthesized but is mistargeted to mitochondria. There are more than 50 mutations identified in the gene for AGT. Four mutations, G170R, 33_34insC, F152I and I244T account for more than 50% of PH1 alleles. The question arose whether there are ethnic differences in PH1 genotype. Methods: The published data on mutations in the AGT gene were examined with respect to recurrences and geographic or ethnic association. The mutations that have been found in at least 2 unrelated individuals were considered. Results: Two common mutations, G170R and 33_34insC showed no obvious ethnic associations and have been found in a variety of populations. A third common PH1 mutation, I244T, has a strong association with people from a Spanish or North African background. A particularly high frequency among Canary Islands PH1 patients suggests a probable founder effect. Between these two extremes are a number of mutations that recur at low frequency within certain ethnic groups. Conclusions: Ethnic associations of PH1 genotypes span a spectrum ranging from limited recurrences confined to a population group, to a probable founder effect.
WLAN-based Indoor Positioning System: experimental results for stationary and tracking MS

Positioning systems for indoor area using the existing wireless local area network infrastructure have been suggested. To provide location aware services, obtaining the position of a user accurately is important. Location fingerprinting schemes are the most promising. In this paper we present some experimental results toward such a systematic study and discuss some issues related to the indoor positioning.
Anti-Angiogenesis, Gene Therapy, and Immunotherapy in Malignant Gliomas

Malignant gliomas remain associated with poor prognosis and the cause of significant morbidity. In 2010, there was excitement that recent spectacular advancements in our basic understanding of their molecular pathogenesis, angiogenesis and new gene transfer technol‐ ogies will turn the tide in our favor. The negative results of several costly phase III clinical trials are sobering; unfortunately, they take us back to the drawing board in terms of how we can improve our methods and why brain cancer has this incredible ability to resist therapy. This chapter is organized as follows. We start by an overview of the classification and signif‐ icance of malignant gliomas. We proceed to reviewing the molecular pathogenesis of angio‐ genesis and the development of new treatment modalities against anti-angiogenesis targets, some of which were tested in Phase III clinical trials. Before considering immunotherapy strategies and targets for malignant gliomas, we review basic concepts in immunology and discuss the unique immunological features of the central nervous system (CNS). Finally, we discuss gene therapy vectors, strategies, and clinical trials in malignant gliomas. We conclude by an analysis of our current limitations, possible tumor mechanisms for resisting treatments, and what we can do to improve the outcome.
All-optical packet switching using a photonic passive multiple encoder/decoder

A novel passive planar multiple-encoder/decoder has been fabricated, that generates and recognizes simultaneously 16 photonic codes in parallel manner. Optical packet switching has been experimentally demonstrated and 10 Gb/s packets have been switched according to their own destination label with a processing speed of 13 Gpps. A BER less than 10/sup -12/ has been measured in both back-to-back and 50 km transmission experiments.
Fluoride Intake by Children at Risk for the Development of Dental Fluorosis: Comparison of Regular Dentifrices and Flavoured Dentifrices for Children

The aim of the present study was to determine fluoride intake by children at risk of dental fluorosis according to the type of dentifrice used. Forty-two volunteers aged between 20 and 30 months, from 2 kindergartens, were supervised while brushing their teeth with regular dentifrices (nominally 1,500 ppm F) and dentifrices flavoured for children (nominally 1,100 ppm F), brushing 3 times with each type in random order to minimize bias. The amount of fluoride ingested was determined by subtracting the weight of dentifrice recovered from the weight used and calculating the mean of the 3 brushings. Fluoride was analyzed with specific electrodes. Parents were asked how often the children brushed their teeth and the daily tooth brushing frequency was used to calculate the daily fluoride intake. The average fluoride intake using regular dentifrices and those flavoured for children was 0.567 ± 0.300 and 0.630 ± 0.320 mg F/day, respectively, corresponding to doses of 0.046 ± 0.023 and 0.051 ± 0.026 mg F/kg/day (p > 0.05). Fluoride intake was slightly higher with the use of dentifrices flavoured for children. Moreover, the dose to which children were exposed with either type of dentifrice was very close to that which is considered the limit (0.05–0.07 mg F/kg/day).
Germ cells enter meiosis in a rostro‐caudal wave during development of the mouse ovary

Germ cells in the mouse embryo remain undifferentiated until about 13.5 days post‐coitum (dpc), when male germ cells enter mitotic arrest and female germ cells enter meiosis. The molecular signals and transcriptional control mechanisms governing the differential fate of germ cells in males and females remain largely unknown. In order to gain insights into the behavior of germ cells around this period and into likely mechanisms controlling entry into meiosis, we have studied by wholemount in situ hybridization the expression pattern of two germ cell‐specific markers, Oct4 and Sycp3, during mouse fetal gonad development. We observed a dynamic wave of expression of both genes in developing ovaries, with Oct4 expression being extinguished in a rostro‐caudal wave and Sycp3 being upregulated in a corresponding wave, during the period 13.5–15.5 dpc. These results indicate that entry into meiosis proceeds in a rostro‐caudal progression, in turn suggesting that somatically derived signals may contribute to the control of germ cell entry into meiosis in developing ovaries. Mol. Reprod. Dev. 68: 422–428, 2004. © 2004 Wiley‐Liss, Inc.
Low Complexity Hybrid Beamforming Based on Orthogonal Constraint and Phase Extraction

Hybrid beamforming (HBF) has been widely accepted to offer a compromise between cost and system performance in millimeter wave (mmWave) systems, while its performance is highly dependent on the corresponding computation complexity. Using an assumption of orthogonal constraint and phase extraction, an effective HBF algorithm is presented in this paper, which consists of a digital beamformer (DBF) stage and an analog beamformer (ABF) stage. Firstly, the optimal DBF with orthogonal constraint is derived for a given RF beamformer. Secondly, when the orthogonal property of the digital beamformer is enabled, the analog beamformer can be developed by extracting the phases of the unconstraint solution of the optimization in RF domain. Specifically, we consider the case of that the number of RF chains is equal to the number of data streams, which can further improve the energy efficiency of mmWave systems. Simulation results show that our proposed algorithm can effectively approach the full digital beamformer performance limit.
The validity of the Tritrac-R3D Activity Monitor for the assessment of physical activity in children.

The purpose of this study was to evaluate the validity of the Tritrac-R3D Activity Monitor, a new instrument designed to improve assessments of physical activity. Comparisons were made with a heart rate monitor and with a Caltrac Activity Monitor. Thirty-five children (ages 9-11 years) were monitored on 3 different school days with all 3 instruments. The Tritrac was moderately correlated with the heart rate monitor (r = .58) and highly correlated with the Caltrac monitor (r = .88). By taking advantage of the minute-by-minute timing capability of the Tritrac and the heart rate monitors, it was discovered that the correlations between these instruments were highest during free play situations (lunch/recess, recess, after school) and were lower when activity was more limited (class time) or structured (physical education). The ability of the Tritrac to assess activity on a minute-by-minute basis may greatly enhance its overall utility.
A comparison of stable isotope ratios (1807160 and 13C/12C) between two species of hydrothermal vent decapods {Alvinocaris lusca and Munidopsis subsquamosa)

Stable isotope ratios (180/160 and I3C/12C) in calcium carbonate exoskeletons of shrimp Alvinocaris lusca and galatheid squat lobsters Munidopsis subsquamosa from hydrothermal vents may provide a record of post-molt water temperature and chemistry experienced by each individual. Shrimp and galatheids appear to occupy distinct environmental regimes which are well-defined in terms of 6'80 and 613C values, and which correspond to specific regions of vent habitats. Each species may occupy these areas in a complex manner, dependent on size, sex, and reproductive state. Several mechanisms that might maintain these differences in distribution are proposed.
A service-oriented architecture to enable participatory planning: an e-planning platform

Recent advances in Web technologies have opened avenues to create socio-technical platforms that can empower citizens in urban planning processes. The rise of the GeoWeb and the popularity of Web 2.0 collaborative tools can facilitate the development of a new generation of bottom-up Public Participatory GIS (PPGIS) platforms that can incorporate user-generated content into Spatial Data Infrastructures (SDIs). New service-based delivery mechanisms can provide architectural flexibility and adaptability, and enable the public to benefit from ubiquitous information access. From an e-participation perspective, Web 2.0 social networking functions support interactive communication among various PPGIS stakeholders, e.g., citizens, planners, and decision makers. The main contribution of this article is to present a reference architecture for e-planning platforms that (1) facilitates effective e-participation by allowing multidirectional map-based communication among various land development stakeholders (e.g., planners, decision makers, citizens, etc.), and (2) enables incorporation of visualization, evaluation, and discussion capabilities to support community planning processes. To achieve this, we developed a service-oriented architecture (SOA) that exploits SDI principles and Web 2.0 technologies. The platform architecture allows heterogeneous data sources, analytical functionality and tools, and presentation frameworks to be plugged into a coherent system to provide a planning and decision support platform. We present two real-world implementations of the proposed architecture that have been developed to support community engagement in the City of Calgary, Canada.
Fast thermal analysis of TSV-based 3D-ICs by GMRES with symmetric successive over-relaxation (SSOR) preconditioning

Thermal issue is a leading design constraint for three-dimensional integrated circuits (3D-ICs) and through silicon vias (TSVs) are used to reduce the temperature of 3D-ICs effectively. In this paper, the finite difference method-based heat conduction equations is proposed for the thermal analysis of the TSV structures in 3D-ICs and generalized minimum residual method (GMRES) with symmetric successive over-relaxation (SSOR) preconditioning is utilized to solve the resulting temperature matrix equations. Simulation results show the accuracy and efficiency of the proposed method.
Reed Solomon coded PPM for Terrestrial FSO Links

Free space optical communications (FSO) are fast emerging as the most promising approach for addressing the emerging broadband access network and its "last mile" bottleneck. However, atmospheric attenuations and weather dependence remain the major hurdle in the wide scale acceptability of the technology. This paper proposes performance enhancement using higher state modulation schemes (i.e. 16 and 256-PPM) which promises a gain upto 25 dB when combined with RS codes as compared to the current widely used 2 state modulation mechanisms. The "RS-coded PPM" is shown as an extremely robust and well performing coded-modulation scheme for future FSO systems using a novel approach to terrestrial FSO channel modeling.
Flexible Solution-Gated Graphene Field Effect Transistor for Electrophysiological Recording

Graphene represents a high-performance material for field effect transistor (FET) manufacture. As a monolayer of carbon atoms, graphene offers flexibility, high carrier mobility, and transparency. Solution-gated graphene FETs based on flexible substrates have been developed for various applications. However, none of these FETs offer both flexibility and good insulation from the electrolyte simultaneously. This would restrict their applicability in certain areas, such as implantation. To solve this problem, we used commercially available graphene and polyimide to fabricate a graphene FET. Photosensitive polyimide was used as both substrate and insulator for our device. Two Au electrodes were used separately as source and drain, and the graphene was exposed to an electrolytic solution to form a solution-gated structure. In this paper, we have studied the resistance variation between source and drain during specific fabrication steps to optimize the fabrication process. By analyzing the FET performance after repeated bending tests, our device's performance reliability was also confirmed. When compared with similar published flexible devices, our FET showed higher transconductance and lower noise levels. Also, neural activities were recorded from cortex neurons cultured on graphene FET for the first time, which proved our device's biocompatibility and demonstrated its potential for electrophysiological applications.
Coalition-based bidding strategies for integrating renewable energy sources in electricity market

In this paper we propose a cooperation framework to analyze coalition-based bidding strategies in electricity market when participants have renewable energy sources such as solar photovoltaic and wind farms. Along with quantile bidding strategy using probabilistic distribution of renewable generation, we also consider a forecast bidding strategy. We show that the grand coalition incentivizes all participants when the market rule forces participants to bid their minimum commitment, which incurs penalty if not fulfilled, and excess generation may be spilled for free or at no cost. Simulations show that the forecast bidding outperforms the previous quantile bidding, e.g., individual and social welfare can increase by up to 97% and 67%, respectively.
Recurrent Human Pose Estimation

Human pose estimation is the task of estimating the joint locations of one or multiple people within an image. It is a core challenge in computer vision because it forms the foundation of more complex tasks such as activity recognition and motion planning. For example, joint locations have been used to supplement other visual features to determine the trajectory of a person through a sequence of video frames. In the past, the leading techniques for pose estimation were the deformable parts model and its variants. These approaches used convolutions of fast part detectors over the input image to generate a coherent joint configuration [3]. More recently, deep learning techniques such as convolutional neural networks as well as optimization methods such as mixed integer programs have achieved state of the art results, for detecting both single and multiple people. From a probabilistic perspective, pose estimation is the task of finding a joint configuration of n joints, y1, y2, . , yn, given a source image x, i.e. argmaxy1,. ,yn p(y1, .yn|x). Several state of the art methods have attempted to calculate this directly with a convolutional neural net. While this has worked very well, the natural dependencies between human joints suggest that explicitly modeling these dependencies may give a boost in performance. This corresponds to calculating
Immunocapture Loop Mediated Isothermal Amplification for Rapid Detection of Tomato Yellow Leaf curl Virus (TYLCV) without DNA Extraction

To diminish the time required for some diagnostic assays including polymerase chain reaction (PCR), loopmediated isothermal amplification (LAMP; due to mainly DNA extraction step) and also DAS-ELISA into a minimum level, an innovative immunocapture LAMP (IC–LAMP) and immunocapture PCR (IC-PCR) protocol on the basis of Tomato Yellow Leaf curl Virus (TYLCV) genome were used and optimized. Even though DAS-ELISA, IC-PCR and IC–LAMP assays could successfully detect positive infected plant samples, considering the time, safety, sensitivity, cost, no need of DNA extraction and simplicity the last one was overall superior. The hydroxynaphthol blue could produce long stable colour change and brightness in a close tube-based approach to prevent cross-contamination risk. Altogether, as IC–LAMP is sensitive, cost effective, fairly user friendly and also can generate more accurate results than previous diagnostic procedures, we accordingly propose this assay as a highly reliable alternative viral recognition system regarding TYLCV recognition and probably other viral-based diseases.
Red Cells with Paroxysmal Nocturnal Hemoglobinuria-phenotype in Patients with Acute Leukemia

Abstract CD55 and CD59 are complement regulatory proteins that are linked to the cell membrane via a glycosyl-phosphatidylinositol anchor. They are reduced mainly in paroxysmal nocturnal hemoglobinuria (PNH) and in other hematological disorders. However, there are very few reports in the literature concerning their expression in patients with acute leukemias (AL). We studied the CD55 and CD59 expression in 88 newly diagnosed patients with AL [65 with acute non-lymphoblastic leukemia (ANLL) and 23 with acute lymphoblastic leukemia (ALL)] using the sephacryl gel test, the Ham and sucrose lysis tests and we compared the results with patients' clinical data and disease course. Eight patients with PNH were also studied as controls. Red cell populations deficient in both CD55 and CD59 were detected in 23% of ANLL patients (especially of M0, M2 and M6 FAB subtypes), 13% of ALL and in all PNH patients. CD55-deficient erythrocytes were found in 6 ANLL patients while the expression of CD59 was decreased in only 3 patients with ANLL. No ALL patient had an isolated deficiency of these antigens. There was no correlation between the existence of CD55 and/or CD59 deficiency and the percentage of bone marrow infiltration, karyotype or response to treatment. However no patient with M3, M5, M7 subtype of ANLL and mature B- or T-cell ALL showed a reduced expression of both antigens. The deficient populations showed no alteration after chemotherapy treatment or during disease course. This study provides evidence about the lower expression of CD55 and CD59 in some AL patients and the correlation with their clinical data. The possible mechanisms and the significance of this phenotype are discussed.
Formação de professores de Matemática: um estudo das contribuições da psicologia

Esta investigacao trata a tematica da formacao inicial do professor de Matematica e a Psicologia da Educacao Matematica, no contexto da Educacao Matematica. Analisa as possibilidades e potencialidades do conhecimento psicologico, em colaborar no enfrentamento dos desafios do processo de ensino e aprendizagem de Matematica. Teve como objetivo investigar as contribuicoes da Psicologia na profissionalizacao docente, em sua insercao no curso de Licenciatura em Matematica. Caracterizou-se como uma pesquisa bibliografica, numa abordagem qualitativa, uma aproximacao a compreensao da efetividade das contribuicoes da Psicologia, com base nos estudos ja realizados nesse enfoque, nas concepcoes de formacao do professor como profissional investigador pratico reflexivo, e das teorias psicologicas de desenvolvimento e de aprendizagem mais significativas ao campo da Educacao Matematica. Indica a importância da Psicologia da Educacao Matematica para a formacao do professor de Matematica, e defende a sua insercao como componente curricular em nivel da Licenciatura
Evaluatfon of soft handover algorithms for UMTS

Soft handover (HO) is becoming quite important because of its suitability for CDMA based systems. Soft handover promises better performance than hard handover. The two most well-known benefits are fade margin improvement and higher uplink capacity, while the disadvantages include lower downlink capacity and more complex implementation. Proper design of handover is one of the main challenges in mobile communications, since it has a great impact on the system performance and capacity. Whereas in hard handover a definite decision is made on whether to handover or not, in soft handover a conditional decision is made based on the variety of parameters involving several base stations. This makes the soft handover design and parameter optimisation even more complex. Several initiation algorithms have been used and proposed in IS-95 and CDMA2000 respectively and their performances have been evaluated in literature. However, their performance have not been compared under similar conditions in terms of propagation, environment and mobility behaviour. In our study, four different soft handover algorithms have been considered, their performance have been evaluated in the same operating environments and conditions and the corresponding results are reported.