Miracle-dz/UniFAR-FTUs huggingface dataset:
Purification and Characterization of a Fibrinolytic Enzyme from Bacillus pumilus 2.g Isolated from Gembus, an Indonesian Fermented Food

Bacillus pumilus 2.g isolated from gembus, an Indonesian fermented soybean cake, secretes several proteases that have strong fibrinolytic activities. A fibrinolytic enzyme with an apparent molecular weight of 20 kDa was purified from the culture supernatant of B. pumilus 2.g by sequential application of ammonium sulfate precipitation, ion-exchange chromatography, and hydrophobic chromatography. The partially purified enzyme was stable between pH 5 and pH 9 and temperature of less than 60°C. Fibrinolytic activity was increased by 5 mM MgCl2 and 5 mM CaCl2 but inhibited by 1 mM phenylmethylsulfonyl fluoride (PMSF), 1 mM sodium dodecyl sulfate (SDS), and 1 mM ethylenediaminetetraacetic acid (EDTA). The partially purified enzyme quickly degraded the α and β chains of fibrinogen but was unable to degrade the γ chain.
Application of synchronous and stationary frame controllers for unbalanced and nonlinear load compensation in 4-leg inverters

This paper presents inverter control strategies to compensate for the distorting effects of unbalanced and nonlinear loads in 4-leg inverter-fed power systems. Synchronous frame controllers are utilized at selected frequencies to eliminate positive and negative sequence distortion. Additionally, stationary frame controllers are employed to attenuate zero sequence distortion due to nonzero neutral currents. Combined with fundamental control this strategy is demonstrated to achieve a high level of performance under challenging loading conditions.
A Framework for Evaluation of OWL Biomedical Ontologies Based on Properties Coverage

Biomedical ontologies are being developed in a great quantity since the last decade. Due to the complex structure of ontologies and difficult terminologies of biomedical domain, the evaluation of these ontologies turns out to be a challenging task. It is utmost need of current ontology researchers and developers to evaluate the quality of these biomedical ontologies so that the applicability and reuse of these ontologies will be improved. In motivation of this need we have proposed a methodology of evaluating the quality of biomedical ontologies with respect to basic ontology structural building blocks especially with respect to properties or relations including object properties, data properties, annotation properties, inverse properties, functional properties, symmetric properties, asymmetric properties and reflexive properties. SPARQL queries are used to extract their population frequency. Experimentation provide evidences that these structural properties/relations between the concepts are of core significance in ontology evaluation.
Gain-of-function mutation in TRPV4 identified in patients with osteonecrosis of the femoral head

Background Osteonecrosis of the femoral head is a debilitating disease that involves impaired blood supply to the femoral head and leads to femoral head collapse. Methods We use whole-exome sequencing and Sanger sequencing to analyse a family with inherited osteonecrosis of the femoral head and fluorescent Ca2+ imaging to functionally characterise the variant protein. Results We report a family with four siblings affected with inherited osteonecrosis of the femoral head and the identification of a c. 2480_2483delCCCG frameshift deletion followed by a c.2486T>A substitution in one allele of the transient receptor potential vanilloid 4 (TRPV4) gene. TRPV4 encodes a Ca2+-permeable cation channel known to play a role in vasoregulation and osteoclast differentiation. While pathogenic TRPV4 mutations affect the skeletal or nervous systems, association with osteonecrosis of the femoral head is novel. Functional measurements of Ca2+ influx through mutant TRPV4 channels in HEK293 cells and patient-derived dermal fibroblasts identified a TRPV4 gain of function. Analysis of channel open times, determined indirectly from measurement of TRPV4 activity within a cluster of TRPV4 channels, revealed that the TRPV4 gain of function was caused by longer channel openings. Conclusions These findings identify a novel TRPV4 mutation implicating TRPV4 and altered calcium homeostasis in the pathogenesis of osteonecrosis while reinforcing the importance of TRPV4 in bone diseases and vascular endothelium.
Featureless similarities for terms clustering using tree-traversing ants

Besides being difficult to scale between different domains and to handle knowledge fluctuations, the results of terms clustering presented by existing ontology engineering systems are far from desirable. In this paper, we propose a new version of ant-based method for clustering terms known as Tree-Traversing Ants (TTA). With the help of the Normalized Google Distance (NGD) and n° of Wikipedia (n°W) as measures for similarity and distance between terms, we attempt to achieve an adaptable clustering method that is highly scalable across domains. Initial experiments with two datasets show promising results and demonstrated several advantages that are not simultaneously present in standard ant-based and other conventional clustering methods.
A Hilbert Scheme in Computer Vision

Abstract Multiview geometry is the study of two-dimensional images of three-dimensional scenes, a foundational subject in computer vision. We determine a universal Gröbner basis for the multiview ideal of $n$ generic cameras. As the cameras move, the multiview varieties vary in a family of dimension $11n\,-\,15$ . This family is the distinguished component of a multigraded Hilbert scheme with a unique Borel-fixed point. We present a combinatorial study of ideals lying on that Hilbert scheme.
Object Detection, Classification, Tracking and individual Recognition for Sea Images and Videos

Manually monitoring the population displacement of fish species and the whale individuals is a painful and definitely unscalable process. Video data about fishes often require laborious visual analysis, moreover biologists often use photos of whale caudal for further analysis as it is the most discriminant pattern for distinguishing an individual whale from another. Therefore two challenges were announced in the SeaCLEF of LifeCLEF campaign, one for automatic fish categorization and enumeration, and another for automatic whale individual recognition based on visual contents. We elaborated a complex sys-tem to detect, classify and track objects (fishes) in underwater video by examining each image frame of it. We used Kalman filter to track the moving objects, and Hungarian method was used to match the pair of the objects in consecutive time periods because of many fishes. We categorized the detected fishes with C-SVC classifier, as an advanced SVM (Support Vector Machine) classifier. As further improvement we used color histograms and discriminant training method for filtering out false detections. For whale individual recognition we elaborated another system to compare the individuals by applying BoW model, during which Harris-Laplace detector and dense SIFT for creating low-level features. After that GMM based Fisher vectors were calculated and compared to each other with RBF kernel function. In addition to this we tried background segmentation as preprocessing.
Effects of α-lipoic acid and L-carnosine supplementation on antioxidant activities and lipid profiles in rats

α-Lipoic acid and L-carnosine are powerful antioxidants and are often used as a health supplement and as an ergogenic aid. The objective of this study was to investigate the effects of α-lipoic acid and/or L-carnosine supplementation on antioxidant activity in serum, skin, and liver of rats and blood lipid profiles for 6 weeks. Four treatment groups received diets containing regular rat chow diet (control, CON), 0.5% α-lipoic acid (ALA), 0.25% α-lipoic acid + 0.25% L-carnosine (ALA + LC), or 0.5% L-carnosine (LC). Superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) and lipid peroxidation products, malondialdehyde (MDA) concentrations, were analyzed in serum, skin, and liver. Blood lipid profiles were measured, including triglycerides (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), and low density lipoprotein cholesterol (LDL-C). Skin and liver SOD activities of the ALA and LC groups were higher than those of the CON group (P < 0.05), but serum SOD activity was higher only in the LC group compared to that in the CON group (P < 0.05). Additionally, only liver GSH-Px activity in the LC group was higher than that of the CON and the other groups. Serum and skin MDA levels in the ALA and LC groups were lower than those in the CON group (P < 0.05). Serum TG and TC in the ALA and ALA + LC groups were lower than those in the CON and LC groups (P < 0.05). The HDL-C level in the LC group was higher than that in any other group (P < 0.05). LDL-C level was lower in the ALA + LC and LC groups than that in the CON group (P < 0.05). Thus, α-lipoic acid and L-carnosine supplementation increased antioxidant activity, decreased lipid peroxidation in the serum, liver, and skin of rats and positively modified blood lipid profiles.
Compressive sampling of natural images using bandelet basis

Bandelets transform exploits geometric information of image to determine bandelets coefficients. Bandelets basis has been used for compression of geometrical images and image denoising. In this paper, bandelets basis are used for compressive imaging of natural images using benchmark and efficient l1 minimization algorithms. Conventional compressive sampling matrices would not be suitable to extract geometric information required for construction bandelets basis. In this work, a so-called regular point sampling matrix is used to find out the geometric regularity of images. The experimental results on a set of natural images show that natural images can be reconstructed by using bandelet basis with higher PSNR and good visual quality. The bandelets based compressive sampling method outperformed conventional compressive imaging frameworks.
Release behaviour and toxicity evaluation of levodopa from carboxylated single-walled carbon nanotubes

This work explores the potential use of commercially obtained, carboxylated, single-walled carbon nanotubes (SWCNT–COOH) as nanocarriers for the antiparkinson drug, levodopa (LD). The resulting nanohybrid was characterized using materials characterization methods including Fourier transform infrared spectroscopy, Raman spectroscopy, elemental analysis, UV–vis spectroscopy and scanning electron microscopy. The results showed that SWCNT–COOH were able to form supramolecular complexes with LD via a π–π stacking interaction and exhibited favourable, slow, sustained-release characteristics as a drug carrier with a release period over more than 20 h. The results obtained from the drug release studies of LD at different pH values showed that the LD-loaded nanohybrid is pH activated. The release kinetics of LD from SWCNT–COOH were well-described by a pseudo-second-order kinetic model. A cytotoxicity assay of the synthesized nanohybrid was also carried out in PC12 cell lines (a widely used, in vitro Parkinson’s model for neurotoxicity studies) using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay in order to investigate their possible effects on normal neuronal cells in vitro. It was found that the synthesized nanohybrid did not compromise the cell viability and the PC12 cells remained stable throughout the experiments up to 72 h after treatment.
Generating Optimal Test Set for Neighbor Factors Combinatorial Testing

Combinatorial testing is a specification-based testing method, which can detect the faults triggered by interaction of factors. For one kind of software in which the interactions only exist between neighbor factors, this paper proposes the concept of neighbor factors combinatorial testing, presents the covering array generation algorithms for neighbor factors pair-wise (N=2) coverage, neighbor factors N-way (Nges2) coverage and variable strength neighbor factors coverage, and proves that the covering arrays generated by these three algorithms are optimal. Finally we analyze an application scenario, which shows that this approach is very practical
Isolation and Identification of Novel Disaccharide of κ-L-Rhamnose from Penicillium chrysogenum

The dry biomass and protein content in culture filtrate of Penicillium chrysogenum, increase with increasing the time of incubation. On the contrary, carbohydrate content of the culture filtrate was decreased with increasing the incubation time. The amount of exodisaccharide (EDS) after 5 and 10 days of cultivation periods was 0.6 and 2.5 g/l, respectively. The yield (g of biomass/g of reducing sugars) was obtained after 5 days (0.7 g/g) and 10 days (1.44 g/g), also the maximum EDS/biomass (g/g) ratio after 10 days was 0.17 g/g which is 2.13 times higher than in case after 5 days (0.08 g/g). The 1 HNMR spectrum is well representation of protons from gycosidic groups of carbohydrates. The signal at 5.261 and 1.244 ppm were assigned to the anomeric and methyl protons at position-6, respectively, of ∝-L-rhamnopyranosyl residues; also the signals at 3.895, 3.759 and 3.508 ppm were assigned to H2, H5 and H4, respectively, of a-L-rhamnopyranosyl residues. FT-IR spectrum is consistent with those of typical carbohydrates. The m/z is at 289 with base peak 161 with relative abundance 100%. The EDS is thermally stable at all temperatures tested the temperature was increased by 100°C.
contribution to the XVIII ISPRS Congress Vienna 1996 International Archives for Photogrammetry and Remote Sensing, Volume XXXI, Part B, Commission VII IN SITU BRDF MEASUREMENTS OF SELECTED SURFACE MATERIALS TO IMPROVE ANALYSIS OF REMOTELY SENSED MULTISPECTRAL IMAGERY

The spectral bidirectional reeectance distribution function (BRDF) of selected artiicial surfaces (e. g. roof materials) was measured under natural illumination. Data were obtained with a spectrometer in the wavelength range 600 nm { 900 nm with a spectral resolution of 5 nm, using 61 spectral bands. The samples were placed on a goniometer, which allowed to set all the desired angles of incidence and reeection. A Spectralon panel (made by Labsphere Inc., Boulder, Colorado) was used as a reference target for determining the incoming irradiance. The BRDF of this Spectralon panel was measured in the laboratory. The BRDF of the Spectralon panel is not Lambertian, however it obeys Helmholtz's theorem of reciprocity. For the in situ measurements, an additional measurement was made for each combination of angles with the samples being shadowed, in order to determine the contribution of sky light. The samples could be tted to a function which was developed by Walthall, 1985] and modiied by Liang, 1994]. In this work, the function was extended by a specular peak, increasing the number of free parameters to 7. The diiuse part of the BRDF of the samples does not vary in a systematic way. The intensity of the specular peak grows with increasing zenith angles. werden.
DWVP : Detection of Web Application Vulnerabilities using Parameters of Web Form

As daily use of Internet is expanding exponentially and access of Internet become more prevalent in our daily life but at the same time web application are becoming most attractive targets for hacker and cyber criminals. In this paper we are implementing intrusion detection system with the use of karp-rabin string matching algorithm for detecting input validation attacks in the web application running on internet. The existing IDS for Input validation attacks are programming language dependent. The proposed IDS is a language independent system that works for any web application developed with the use of any programming languages. In addition proposed technique detects directory traversal attacks, buffer overflow attacks, cross site scripting attacks and SQL injection attacks, those attacks can not be detected in the existing IDS. This is an automatic technique for detection of such attacks over the internet. Proposed technique is based on the web application parameters which are in form of POST and GET which has generalized structure and values. This technique reduces analysis time of input validation attacks.
The Hyperbolic Lattice Point Count in Infinite Volume with Applications to Sieves

We develop novel techniques using abstract operator theory to obtain asymptotic formulae for lattice counting problems on infinite-volume hyperbolic manifolds, with error terms which are uniform as the lattice moves through "congruence" subgroups. We give the following application to the theory of affine linear sieves. In the spirit of Fermat, consider the problem of primes in the sum of two squares, f(c,d)=c^2+d^2, but restrict (c,d) to the orbit O = (0,1). Gamma, where Gamma is an infinite-index non-elementary finitely-generated subgroup of SL(2,Z). Assume that the Reimann surface Gamma\H^2 has a cusp at infinity. We show that the set of values f(O) contains infinitely many integers having at most R prime factors for any R>4/(delta-theta), where theta>1/2 is the spectral gap and delta 149/150, then we can take theta=5/6, giving R=25. The limit of this method is R=9 for delta-theta>4/9. This is the same number of prime factors as attained in Brun's original attack on the twin prime conjecture.
Attitude towards sex offenders : an Icelandic sample of psychology students and the general public

This study explores attitude towards sex offenders in an Icelandic population. A questionnaire was administered both online and via paper and pencil. The written survey was given to psychology students at Reykjavík University (N = 78). For the general public the survey was administered online (N = 92). The total number of participants was 170, 128 females and 42 males. The Attitude Towards Sex Offender scale (ATS) was used to explore the participants’ attitude toward sex offenders. This study’s aim was to see if there was any; 1) gender difference, 2a) difference between victim type (vignette), 2b) gender difference within vignettes, 3) difference between the general public and psychology students and 4) difference between those who had been sexually abused or knew of someone who had been sexually abused and those that had not, in attitude towards sex offenders. An independent ttest found no significant difference in the average ATS scores between those variables however there was a significant 5) difference between first and second year psychology students. Second year students held a more positive attitude towards sex offenders than first year students.
Prenatal and postnatal animal models of immune activation: Relevance to a range of neurodevelopmental disorders

Epidemiological evidence has established links between immune activation during the prenatal or early postnatal period and increased risk of developing a range of neurodevelopment disorders in later life. Animal models have been used to great effect to explore the ramifications of immune activation during gestation and neonatal life. A range of behavioral, neurochemical, molecular, and structural outcome measures associated with schizophrenia, autism, cerebral palsy, and epilepsy have been assessed in models of prenatal and postnatal immune activation. However, the epidemiology‐driven disease‐first approach taken by some studies can be limiting and, despite the wealth of data, there is a lack of consensus in the literature as to the specific dose, timing, and nature of the immunogen that results in replicable and reproducible changes related to a single disease phenotype. In this review, we highlight a number of similarities and differences in models of prenatal and postnatal immune activation currently being used to investigate the origins of schizophrenia, autism, cerebral palsy, epilepsy, and Parkinson's disease. However, we describe a lack of synthesis not only between but also within disease‐specific models. Our inability to compare the equivalency dose of immunogen used is identified as a significant yet easily remedied problem. We ask whether early life exposure to infection should be described as a disease‐specific or general vulnerability factor for neurodevelopmental disorders and discuss the implications that either classification has on the design, strengths and limitations offuture experiments. © 2012 Wiley Periodicals, Inc. Develop Neurobiol, 2012
Establishing a Secure Base to Increase Exploration of Diversity in Groups

ABSTRACT All groups can be considered multicultural, and group members often present with issues that stem from contextual factors related to cultural identities, including experiences with oppression. Therefore, group leaders must be able to effectively facilitate deep intercultural dialogues in psychotherapy groups, and we suggest that an understanding of attachment theory can help leaders engage group members in these dialogues. In order to demonstrate how attachment theory can be applied to the exploration of diversity in groups, we provide a case example from an intergroup dialogue group bringing together religious minorities, secular individuals, and Christians over the course of eight weeks. In this example, we focus on the two group members who scored the lowest (Jill) and highest (Sarah) on a measure of attachment anxiety and avoidance to illustrate the experiences of one member with more secure attachment and one with more preoccupied attachment. Specifically, we present data from their weekly reflective journals to explore their different experiences of the group over time. Finally, we discuss the case in terms of attachment theory and highlight implications for group leaders.
A Feature Library Approach to On-line Image Querying and Retrieval for Topographic Applications

In this paper we address the problem of content-based image retrieval using queries on shape and topology. We focus on the particularities of image databases encountered in typical topographic applications, and present the development of a spatial data management system that enables such queries. The query uses as input user-provided sketches of the shape and spatial configuration of the object (or objects) which should appear in the images to be retrieved. The objective of the search is to retrieve images that contain a configuration of objects sufficiently similar to the one specified in the query. Our novel approach introduces the design of a structured feature library that is linked to an integrated image database in addition to the development of the necessary matching tools. We discuss our overall strategy and focus on the use of the feature library to support our queries.
Examination of the Relationship Between Gender, Performance, and Enjoyment of a First-Person Shooter Game

Purpose. The purpose of this work was to explore the relationship between gender, game performance factors, and player enjoyment of a first-person shooter (FPS) video game. Drawing upon the notion that FPS games are gendered spaces in which men are both the intended and ideal participants, we predicted that women’s game enjoyment, in contrast to men’s, would rest on their ability to positively violate negative expectancies associated with FPS games by performing at a high level. Method. Two inter-related studies were employed. The first (preliminary) study used an online survey to assess gender-based expectancy differences. The second (main) study was lab-based. Here, participants played the FPS game COUNTER-STRIKE: GLOBAL OFFENSIVE and provided data on perceived game performance and session enjoyment. Results. The data indicated that men’s enjoyment of a FPS game was not influenced by game performance while women’s enjoyment was, in fact, significantly influenced by both subjective self-relative and objective performance dimensions. Conclusions. The present findings may provide a partial explanation for the persistence of the gender gap relative to FPS preference. Moreover, the current work extends the current scholarly understanding of expectancy value theory (EVT) by investigating the effect of expectancy violations associated with one’s own behavior.