Miracle-dz/UniFAR-FTUs huggingface dataset:
Percutaneous transluminal angioplasty and stent placement for recurrent carotid artery stenosis.

OBJECT Treatment consisting of percutaneous transluminal angioplasty (PTA) and stent placement has recently been proposed as an alternative to surgical reexploration in patients with recurrent carotid artery stenosis following endarterectomy. The authors retrospectively reviewed their experience after performing 25 procedures in 21 patients to assess the safety and efficacy of PTA with or without stent placement for carotid artery restenosis. METHODS The mean interval between endarterectomy and the endovascular procedures was 57 months (range 8-220 months). Seven arteries in five patients were treated by PTA alone (including bilateral procedures in one patient and repeated angioplasty in the same vessel in another). Early suboptimum results and recurrent stenosis in some of these initial cases prompted the authors to combine PTA with stent placement in the treatment of 18 arteries over the past 3 years. No major periprocedural deficits (neurological or cardiac complications) or death occurred. There was one periprocedural transient neurological event, and in one patient a pseudoaneurysm of the femoral artery (at the access site) required surgical repair. In the 16 patients who each underwent at least 6 months of follow-up review, no neurological events ipsilateral to the treated artery had occurred after a mean follow-up period of 27 months (range 6-57 months). Three of five patients who underwent PTA alone developed significant (>50%) asymptomatic restenoses that required repeated angioplasty in one and PTA with stent placement in two patients. Significant restenosis (55%) was observed in only one of the vessels treated by combined angioplasty and stent placement. CONCLUSIONS Endovascular PTA and stenting of recurrent carotid artery stenosis is both technically feasible and safe and has a satisfactory midterm patency. This procedure can be considered a viable alternative to surgical reexploration in patients with recurrent carotid artery stenosis.
A Cation-π Interaction at a Phenylalanine Residue in the Glycine Receptor Binding Site Is Conserved for Different Agonists

Cation-π interactions have been demonstrated to play a major role in agonist-binding in Cys-loop receptors. However, neither the aromatic amino acid contributing to this interaction nor its location is conserved among Cys-loop receptors. Likewise, it is not clear how many different agonists of a given receptor form a cation-π interaction or, if they do, whether it is with the same aromatic amino acid as the major physiological agonist. We demonstrated previously that Phe159 in the glycine receptor (GlyR) α1 subunit forms a strong cation-π interaction with the principal agonist, glycine. In the current study, we investigated whether the lower efficacy agonists of the human GlyR β-alanine and taurine also form cation-π interactions with Phe159. By incorporating a series of unnatural amino acids, we found cation-π interactions between Phe159 and the amino groups of β-alanine and taurine. The strengths of these interactions were significantly weaker than for glycine. Modeling studies suggest that β-alanine and taurine are orientated subtly differently in the binding pocket, with their amino groups further from Phe159 than that of glycine. These data therefore show that similar agonists can have similar but not identical orientations and interactions in the binding pocket and provide a possible explanation for the lower potencies of β-alanine and taurine.
Compensation Based Grid Scheduling

In the grid-computing environment, resources are autonomous, distributed with varying pricing policies. The grid comprises of the contributors and the users who each play a role for certain compensational benefits. The proposed model is a tender contract type that envisages a real market operating on the supply and demand perspectives of a defined commodity. It allows a decentralized selection of contributors by the user for the execution of his job. The goal is to compensate the contributor for his resource and the user to pay less for his job. The contributor benefits by profits and fairness, which is evident as pricing of the resource based on its demand and efficiency. The user is compensated with the successful completion of jobs and fine amount borne by the contributor for not guaranteeing the defined deadline requirements. Simulation and results show that both the contributors and the users are compensated equally well
Effect of grain orientation and local strain on the quality of polycrystalline YBa 2 Cu 3 O 7 superconductive films

The critical current densities of superconducting thin films and their dependence on the film structural characteristics has been a major research interest for more than a decade. Controlling this relationship is crucial if large-scale high-quality YBa 2 Cu 3 O 7 (YBCO) tapes are to be produced. Two major keystones of information have been established in this field. Firstly, there is a direct relationship between the critical current density and the grain-boundary angle in polycrystalline YBCO films. Grain boundaries with a mismatch angle higher than 5° usually result in reduced critical current densities. This detrimental effect of large-angle grain boundaries to the quality of YBCO films has been attributed to strain fields resulting from such grain boundaries. Secondly, the quality of the YBCO film can be enhanced by straining its lattice in specific direction. Here, we report, for the first time, direct experimental results coupling local grain orientation and local strain maps of thin YBCO films deposited on a (001) biaxially textured nickel substrate. These results were correlated to the quality of the film and showed how grain structure in the nickel substrate affects the grain structure in the YBCO films even in the presence of several buffer layers. More importantly, the data show that highquality films with high critical current densities can be produced, in spite of large-angle grain boundaries, if the film is compressed in the range of 0.5% strain normal to the a axis.
Finite element aided measurement of stress fields in different bone layers subject to therapeutic ultrasonic excitation

Physiological effects caused by power ultrasound irradiation are of therapeutic benefits for fracture healing, but sometimes will cause tissue damage. However, these effects are hard to detect by current instruments. The aim of this study is to analyze the behavior of the cancellous bone subject to therapeutic ultrasonic vibration excitation. In this work we adopted a three-dimensional Finite Element Method (FEM) as a virtual measurement tool to study the acoustic-radiation-induced stress fields inside and on the surface of bone to predict the biological effects of ultrasound. The existence of soft tissue was involved in our model construction and the interface between bone and muscle was processed with coupling method. The ultrasound power propagation from muscle to bone was simulated with FEM. The ultrasound radiation was generated by a 2-MHz excitation, and was applied on the surface of soft tissue. In this study, we defined 6 paths of different bone layers to study stress distributions and Coefficient of Variation (CV), and the stress in muscle was also worked out to make comparisons. Simulation results show that the middle bone tissue has a higher mean stress (2027.7 Pa) than the surface (763.3 Pa) and outer layer (1898.1 Pa). Moreover the stress distribution of middle layer is less disturbed (CV = 39.8%).
Designing Truthful Spectrum Double Auctions with Local Markets

Market-driven spectrum auctions offer an efficient way to improve spectrum utilization by transferring unused or underused spectrum from its primary license holder to spectrum-deficient secondary users. Such a spectrum market exhibits strong locality in two aspects: 1) that spectrum is a local resource and can only be traded to users within the license area, and 2) that holders can partition the entire license areas and sell any pieces in the market. We design a spectrum double auction that incorporates such locality in spectrum markets, while keeping the auction economically robust and computationally efficient. Our designs are tailored to cases with and without the knowledge of bid distributions. Complementary simulation studies show that spectrum utilization can be significantly improved when distribution information is available. Therefore, an auctioneer can start from one design without any a priori information, and then switch to the other alternative after accumulating sufficient distribution knowledge. With minor modifications, our designs are also effective for a profit-driven auctioneer aiming to maximize the auction revenue.
ViewFusion: Correlating Structure and Activity Views for Execution Traces

Visualization of data on structure and related temporal activity supports the analysis of correlations between the two types of data. This is typically done by linked views. This has shortcomings with respect to efﬁcient space usage and makes mapping the effect of user input into one view into the other view difﬁcult. We propose here a novel, space-efﬁcient technique that ‘fuses’ the two information spaces – structure and activity – in one view. We base our technique on the idea that user interaction should be simple, yet easy to understand and follow. We apply our technique, implemented in a prototype tool, for the understanding of software engineering datasets, namely static structure and execution traces of the Chromium web browser.
The Deubiquitylation Activity of Ubp8 Is Dependent upon Sgf11 and Its Association with the SAGA Complex

ABSTRACT Covalent modifications of the histone tails and the cross talk between these modifications are hallmark features of gene regulation. The SAGA histone acetyltransferase complex is one of the most well-characterized complexes involved in these covalent modifications. The recent finding that the removal of the ubiquitin group from H2B is performed by a component of SAGA, Ubp8, is intriguing as it assigns two posttranslation modification processes to one complex. In this work, we characterize the association of Ubp8 with SAGA and the effect that acetylation and deubiquitylation have on one another in vitro and in vivo. We found not only that Ubp8 is a part of the SAGA complex, but also that its deubiquitylation activity requires Ubp8's association with SAGA. Furthermore, we found that the Ubp8 association with SAGA requires Sgf11 and that this requirement is reciprocal. We also found that the acetylation and deubiquitylation activities of SAGA are independent of one another. However, we found that preacetylating histone H2B inhibited subsequent deubiquitylation. Additionally, we found that increasing the ubiquitylation state of H2B inhibited the expression of the ARG1 gene, whose repression was previously shown to require the RAD6 ubiquitin ligase. Taken together, these data indicate that the expression of some genes, including ARG1, is regulated by a balance of histone H2B ubiquitylation in the cell.
Reflectance modeling by neural texture synthesis

We extend parametric texture synthesis to capture rich, spatially varying parametric reflectance models from a single image. Our input is a single head-lit flash image of a mostly flat, mostly stationary (textured) surface, and the output is a tile of SVBRDF parameters that reproduce the appearance of the material. No user intervention is required. Our key insight is to make use of a recent, powerful texture descriptor based on deep convolutional neural network statistics for "softly" comparing the model prediction and the examplars without requiring an explicit point-to-point correspondence between them. This is in contrast to traditional reflectance capture that requires pointwise constraints between inputs and outputs under varying viewing and lighting conditions. Seen through this lens, our method is an indirect algorithm for fitting photorealistic SVBRDFs. The problem is severely ill-posed and non-convex. To guide the optimizer towards desirable solutions, we introduce a soft Fourier-domain prior for encouraging spatial stationarity of the reflectance parameters and their correlations, and a complementary preconditioning technique that enables efficient exploration of such solutions by L-BFGS, a standard non-linear numerical optimizer.
A novel self-organizing scheme for 4G advanced networks and beyond

Fourth generation networks and beyond have recently emerged to satisfy the increasing demand for high data rates. Cost-effective means have been designed in 3GPP LTE Advanced standard to significantly enhance coverage and capacity. Huge performance gains can be achieved through increasing nodes density with the introduction of small cells, in a concept called Heterogeneous Network (HetNet). Self-Organizing Network (SON) is a new approach aiming at minimizing human efforts. SON functions include: self-configuration, self-optimization and self-healing. In this context, we have focused on self-configuration of new added Femto Cell combined with a new algorithm for three self-optimization functions: Admission Control (AC), Handover (HO) and Load Balancing (LB). Simulation results witness the performance of our approach through the evaluation of some performance parameters such as: average throughput and cell load.
Three engines to solve verification constraints of decimal Floating-Point operation

Decimal floating-point designs require a verification process to prove that the design is in compliance with the IEEE Standard for Floating-Point Arithmetic (IEEE Std 754-2008). Our work represents three engines, the first engine for the verification of decimal addition-subtraction operation, the second for the verification of decimal multiplication operation, and the third for the verification of decimal fused-multiple-add operation. Each engine solves constraints describing all corner cases of the operation, and generates test vectors to verify these corner cases in the tested design. The paper describes the constraints of each operation and the steps of each engine to solve these constraints.
Bayesian Node Dating based on Probabilities of Fossil Sampling Supports Trans-Atlantic Dispersal of Cichlid Fishes

Divergence-time estimation based on molecular phylogenies and the fossil record has provided insights into fundamental questions of evolutionary biology. In Bayesian node dating, phylogenies are commonly time calibrated through the specification of calibration densities on nodes representing clades with known fossil occurrences. Unfortunately, the optimal shape of these calibration densities is usually unknown and they are therefore often chosen arbitrarily, which directly impacts the reliability of the resulting age estimates. As possible solutions to this problem, two non-exclusive alternative approaches have recently been developed, the “fossilized birth-death” model and “total-evidence dating”. While these approaches have been shown to perform well under certain conditions, they require including all (or a random subset) of the fossils of each clade in the analysis, rather than just relying on the oldest fossils of clades. In addition, both approaches assume that fossil records of different clades in the phylogeny are all the product of the same underlying fossil sampling rate, even though this rate has been shown to differ strongly between higher-level taxa. We here develop a flexible new approach to Bayesian node dating that combines advantages of traditional node dating and the fossilized birth-death model. In our new approach, calibration densities are defined on the basis of first fossil occurrences and sampling rate estimates that can be specified separately for all clades. We verify our approach with a large number of simulated datasets, and compare its performance to that of the fossilized birth-death model. We find that our approach produces reliable age estimates that are robust to model violation, on par with the fossilized birth-death model. By applying our approach to a large dataset including sequence data from over 1000 species of teleost fishes as well as 147 carefully selected fossil constraints, we recover a timeline of teleost diversification that is incompatible with previously assumed vicariant divergences of freshwater fishes. Our results instead provide strong evidence for trans-oceanic dispersal of cichlids and other groups of teleost fishes. (Keywords: node dating; calibration density; relaxed molecular clock; fossil record; Cichlidae; marine dispersal)
Calcifying or Ossifying Fibroma of the Frontal Sinus

CASES of ossifying or calcifying fibroma of the frontal sinus have been described by Benjamins (1938), Simpson et. al. (1944), Woodruff (1945) and others. The patients generally present with displacement of the eye such as occurs in cases of mucocele of the frontal sinus, and may have discomfort and pain in the affected area. Simple removal of the growth is stated to be curative. In this note there is reported another case of this condition; the unusual X-ray appearances are perhaps its most interesting feature. The patient was a middle-aged lady who complained of discomfort and pain around the left eye and also sometimes around the right one, worse on bending or coughing ; from time to time, there were also localized patches of scleral congestion in both eyes. The nose looked normal. Sinus X-rays showed the appearance portrayed in Fig. 1; although it suggests osteomyelitis with sequestra, such a diagnosis is unlikely as the lesion is confined to the sinus. The X-ray appearance did not alter over at least several months. Because of it, a Russell-Harmer operation was performed on the left frontal sinus in a hospital elsewhere about two years previously to our seeing the patient. The following notes were made at that operation : " The bony anterior and inferior walls of the left frontal sinus were densely sclerotic. The sinus cavity appeared empty and its mucous membrane appeared normal. There was a suspicion of exposed and thickened dura. A rubber tube was passed through the fronto-nasal duct from the sinus into the nose and the sinus cavity was filled with a paste of bismuth and glycerine. " We suspected at one time that the X-ray appearances might be due to the bismuth that had been put into the sinus, but our subsequent operation findings disproved this. When we saw the patient we found the scar of the HarmerRussell operation somewhat depressed. Occasionally her forehead appeared somewhat boggy. In view of her continued headaches it was decided to explore the left frontal sinus, although we suspected a psychological and perhaps a vascular element in the headaches; the latter suspicion was not confirmed by the physicians who examined her ; ophthalmologists also could not account for her headaches. Her nasal sinuses other than the left frontal sinus were clear on X-rays, except during a few weeks when she had an acute rhinosinusitis and catarrhal otitis media all of which subsided readily on penicillin administered systemically and her using an ephedrine, penicillin and flavazole solution nasal spray. Her nose, except during this episode, looked normal. As the nature of the lesion was so doubtful and because of the size of the left frontal sinus, this was exposed widely by turning down a flap of the soft
CudaRF: A CUDA-based implementation of Random Forests

Machine learning algorithms are frequently applied in data mining applications. Many of the tasks in this domain concern high-dimensional data. Consequently, these tasks are often complex and computationally expensive. This paper presents a GPU-based parallel implementation of the Random Forests algorithm. In contrast to previous work, the proposed algorithm is based on the compute unified device architecture (CUDA). An experimental comparison between the CUDA-based algorithm (CudaRF), and state-of-the-art Random Forests algorithms (Fas-tRF and LibRF) shows that CudaRF outperforms both FastRF and LibRF for the studied classification task.
Study on the Preparation of 2-Phenyl Imidazole Microcapsule and its Effect on Curing Epoxy Resin

In this paper, 2-phenyl imidazole (2-PZ) microcapsule-type curing agent of epoxy resin were prepared through solvent volatilization with 2-PZ and polymethyl acrylic glycidyl ester (PGMA) as the raw materials. The micro-morphology, shape and structure of the microcapsules were studied by scanning electronic microscope (SEM) and fourier transform infrared spectrum (FT-IR). The curing kinetics of microcapsule curing agent/epoxy resin E-44 curing system were studied using TGA/DSC simultaneous thermal analyzer. Results showed that the preparation method is simple and effective and the prepared 2-PZ microcapsules have smooth surfaces and monodisperse size. And the curing kinetic study of epoxy resin system suggested epoxy resin curing temperature was rising with the increase of heating rate.
Modulation of the amplitude of γ‐band activity by stimulus phase enhances signal encoding

Visual stimulation often leads to elevated fluctuations of the membrane potential in the γ‐frequency range (25–70 Hz) in visual cortex neurons. Recently, we have found that the strength of γ‐band fluctuations is coupled to the oscillation of the membrane potential at the temporal frequency of the stimulus, so that the γ‐band fluctuations are stronger at depolarization peaks, but weaker at troughs of the stimulus frequency oscillation of the membrane potential. We hypothesized that this coupling may improve stimulus encoding. Here, we tested this hypothesis by using a single‐compartment conductance‐based neuron model, with parameters of the input adjusted to reproduce typical features of membrane potential and spike responses, recorded in cat visual cortical neurons in vivo during the presentation of moving gratings. We show that modulation of the γ‐range membrane potential fluctuations by the amplitude of the slow membrane depolarization greatly improves stimulus encoding. Moreover, changing the degree of modulation of the γ‐activity by the low‐frequency signal within the range typically observed in visual cortex cells had a stronger effect on both the firing rates and information rates than changing the amplitude of the low‐frequency stimulus itself. Thus, modulation of the γ‐activity represents an efficient mechanism for regulation of neuronal firing and encoding of the temporal characteristics of visual stimuli.
Publishing and linking transport data on the web: extended version

Without Linked Data, transport data is limited to applications exclusively around transport. In this paper, we present a workflow for publishing and linking transport data on the Web. So we will be able to develop transport applications and to add other features which will be created from other datasets. This will be possible because transport data will be linked to these datasets. We apply this workflow to two datasets: NEPTUNE, a French standard describing a transport line, and Passim, a directory containing relevant information on transport services, in every French city.
Digital Fresnel hologram watermarking

We present a method of digital hologram watermarking using a Fresnel hologram of a real-world 3D object and the fractional Fourier transform. A watermark is encrypted using double random phase fractional Fourier domain encoding technique and then encoded into the digital hologram. The hologram is watermarked in a plane at some known distance from the object so that even if a new hologram is generated from the original hologram the watermark can always be traced by propagating the new hologram back to the object and then onto the watermark plane. The watermark is retrieved successfully using the correct encryption parameters. We consider both numerical (full complex field) and optoelectronic (phase-only) reconstruction methods. We obtain the watermark from different windows of the hologram corresponding to different reconstruction perspectives.