Miracle-dz/UniFAR-FTUs huggingface dataset:
Fiabilité de la référence humaine dans la détection de thème

Dans cet article, nous nous intéressons à la tâche de détection de thème dans le cadre de la reconnaissance automatique de la parole. La combinaison de plusieurs méthodes de détection montre ses limites, avec des performances de 93.1 %. Ces performances nous mènent à remetttre en cause le thème de référence des paragraphes de notre corpus. Nous avons ainsi effectué une étude sur la fiabilité de ces références, en utilisant notamment les mesures Kappa et erreur de Bayes. Nous avons ainsi pu montrer que les étiquettes thématiques des paragraphes du corpus de test comportaient vraisemblablement des erreurs, les performances de détection de thème obtenues doivent donc êtres exploitées prudemment.
A new application of molecularly imprinted materials

We have studied the possibility of shifting a thermodynamically unfavourable enzymatic equilibrium towards product formation via the addition of a highly specific adsorbent. The commercially interesting enzymatic condensation of Z‐L‐aspartic acid with L‐phenylalanine methyl ester to the sweetener aspartame was chosen as the model system. Extremely stable and specific adsorbents for the product Z‐L‐Asp‐L‐Phe‐OMe (Z‐aspartame) were prepared using the emerging technique of molecular imprinting. A considerable increase (40%) in the yield of product was obtained when such adsorbents were present during the enzymatic reaction. The message of this investigation is that the use of such specific, sterilizable adsorbents should be considered for enzymatic processes to increase the yield. Finally, the direct isolation of a product formed by the retrieval of the adsorbents carrying the product can be envisaged, especially if the adsorbents are magnetic. Copyright © 1998 John Wiley & Sons, Ltd.
HERAPY IN D EMENTIA

The article aims at a possible definition of music therapy and underlines the principal differences between the generic and the therapeutic use of music in the field of dementia. The article begins with a brief review about the most recent studies in the international literature, followed by the presentation of the reasons of the efficacy of the music therapeutic approach in the persons living with Alzheimer‟s disease or with dementia. In addition, the article describes a music therapy approach based on the free sonorous-music improvisation and on the psychological intersubjective perspective. In conclusion, you can read the description of some research studies realized with rigorous methodological criteria (scientific approach), and in Appendix 1 a case report regarding music therapeutic treatment of a person with a diagnosis of mixed dementia of mild level (clinical approach).
Using Space-Optimized Tree Visualizaton for Web Site-Mapping

This paper describes a new information visualization technique for web site mapping. It can be used especially for the display of very large web sites in a 2-dimensional space. Our strategy is to optimize the drawing of trees in a geometrical plane and maximize the utilization of display space by allowing more nodes and links to be displayed at a limit screen resolution. To enable the exploration of large web site-maps, we use a modified semantic zooming technique to view the detail of a particular part of the hierarchy at a time based on user's interest. Layout animation is also provided to preserve the mental map while the user is exploring the hierarchy by changing zoomed views.
Ammonium Removal Using a Vertically Moving Biofilm System

Abstract Ammonium-nitrogen (NH4-N) removal using a vertically moving biofilm system was investigated at a temperature of 11°C. The biofilms in this process were grown on biofilm modules, consisting of high surface area plastic media, which were vertically and repeatedly moved up into the air and down into the wastewater. The maximum NH4-N removal efficiency was up to 98.8% and the areal NH4-N removal rates, based on the surface area of the biofilm modules, were within the range of 0.68–1.94 g NH4-N m−2 day−1. The kinetics of ammonium removal occurring after carbonaceous oxidation was completed can be simulated by using a zero-order empirical model. The ammonium removal rate was found to be proportional to the square root of the mass of biofilms on the modules. Monitoring DO concentrations in the bulk fluid showed that the vertically moving biofilm system possessed good aeration efficiency.
Negative Experiences as Learning Trigger: A Play Experience Empirical Research on a Game for Social Change Case Study

This study shows the results gathered from 141 subjects playing the persuasive urban game A Hostile World via a post-game-experience quantitative questionnaire. The aim is to problematize and deepen the role of negative emotions e.g., frustration, rage-explicitly fostered by A Hostile World to increase empathy toward immigrants and foreigners-in triggering an effective learning outcome. A multidisciplinary approach that draws its principles from Sociology, Game Design and Education Studies was applied to lead and structure the analysis. Empirically, a quantitative survey was disseminated to n:141 players addressing negativity and play. Results show that negative experiences in ludic environments offer a precious support if well pondered. Findings are noteworthy because they allow to reflect on negativity and gaming with the support of an empirical investigation, which is a significant source of data for grounded and tangible follow-ups. Therefore, implications concern both scholars and practitioners who intend to use and explore negative emotions in gaming.
Two‐Year Results of a Randomized Placebo‐Controlled Trial of Vertebroplasty for Acute Osteoporotic Vertebral Fractures

We previously reported the results of a randomized controlled trial that found no benefit of vertebroplasty over a sham procedure for acute osteoporotic vertebral fractures up to 6 months. We report here the 12‐month and 24‐month clinical outcomes of this trial. Eligible participants (n = 78) were randomly assigned to receive either vertebroplasty (n = 38) or a sham procedure (n = 40). Randomization was stratified by treatment center, sex, and symptom duration (<6 weeks or ≥6 weeks). Participants, investigators (except the treating radiologists), and outcome assessors were blinded to group assignments. Enrolment occurred between April 2004 and October 2008 with follow‐up completed October 2010. The primary outcome was overall pain measured on a scale of 0 (no pain) to 10 (maximal imaginable pain). Secondary outcomes included pain at rest and at night, disability, quality of life, perceived recovery, and adverse events, including incident clinically apparent vertebral fractures. At 12 and 24 months, complete data were available for 67 (86%) and 57 (73%) participants, respectively. At 12 months participants in the active group improved by 2.4 ± 2.7 (mean ± SD) units in overall pain compared with 1.9 ± 2.8 units in the sham group, adjusted between‐group mean difference (MD) 0.3 (95% confidence interval [CI], –0.9 to 1.5), whereas at 24 months participants in the active group had improved by 3.0 ± 3.1 units compared with 1.9 ± 3.0 units in the sham group, MD 1.1 (95% CI, –0.3 to 2.4). No significant between‐group differences were observed for any of the secondary efficacy outcomes at 12 or 24 months. There were no between‐group differences in incident clinical vertebral fractures up to 24 months (active: n = 14, sham: n = 13), although the study had inadequate power for this outcome. These results provide further evidence that the use of this treatment in routine care is unsupported. © 2014 American Society for Bone and Mineral Research.
Autonomous inertia-sharing control of multi-terminal VSC-HVDC grids

Multi-terminal high-voltage dc (HVDC) grids are expected to experience a continuous expansion in the near future, and have appeared as competitive strategies in transmitting offshore wind and interconnecting multiple ac areas. This paper proposes the inertia sharing concept for the operation of multi-terminal HVDC (MTDC) grids, which can be achieved by the proposed Unified Reference Controller. The control objectives of the VSC stations are no longer limited to the stabilization of dc grid, instead, the requirements in ac side are also met. The interaction dynamics between the ac and dc grid is analyzed for illustrating the proposed concept. In addition, the VSC stations can work in different operation modes based on the unified control architecture, and further smoothly switch the operation modes for flexible maneuver. Simulation results exhibit good performance of the proposed strategy.
A Fuzzy Clustering Algorithm for Image Segmentation Using Dependable Neighbor Pixels

In this paper, a fuzzy clustering algorithm using dependable neighbor pixels is proposed for image segmentation. In order to enhance the segmentation performance, the proposed algortihm utilizes the local statistical information to discriminate dependable neighbor pixels from undependable neighbor pixels, and then allows the labeling of the pixel to be influenced by the dependable neighbor pixels. This algorithm has two advantages: (1) the spatial information with high reliability is incorporated into the objective function so that the segmentation accuracy is guaranteed; (2) the intensity of the spatial constraints is automatically determined by the similarity meature so that the segmentation result is adaptive to the original image. The efficiency of the proposed algorithm is demonstrated by extensive segmentation experiments using both synthetic and real images.
Combination of zolazepam and tiletamine as a sedative and anaesthetic for wombats.

OBJECTIVE To assess the suitability of the combination of zolazepam and tiletamine for routine use as chemical restraint, sedative and anaesthetic in wild wombats. ANIMALS Sixty common wombats, 25 southern hairy-nosed wombats and 40 northern hairy-nosed wombats. PROCEDURE Wombats caught in cage-traps in the wild were given injections of the anaesthetic combination either intramuscularly or intraperitoneally. Anaesthesia was maintained for up to 4 h in some cases, and for 12 h in one case. All wombats were released after anaesthesia. RESULTS AND CONCLUSION This drug combination is effective and apparently safe for the sedation or light anaesthesia of wombats. We did not observe adverse reactions or deaths and the dose range used (4 to 15 mg/kg) demonstrates a wide safety margin. The use of this anaesthetic combination was effective in reducing the stress to wombats from capture and handling.
A Multiphysic Dynamic 1-D Model of a Proton-Exchange-Membrane Fuel-Cell Stack for Real-Time Simulation

This paper presents cell-layer-scale multidomain dynamic 1-D proton-exchange-membrane fuel-cell (PEMFC) stack model using VHDL-AMS modeling language. The model covers three main fuel-cell energy domains: electrical, fluidic, and thermal. The performance and advantages of the VHDL-AMS language are shown in the first part. Then, by means of the ¿top-down¿ modeling approach, the electrical-, fluidic-, and thermal-domain models of the PEMFC stack are addressed in three separate parts. Simulation results are then compared with a Ballard 1.2-kW NEXA fuel-cell system and show a great agreement with experimental data. This complex multidomain VHDL-AMS stack model, containing more than 25 000 state variables and only few empirical coefficients (four parameters identified on the polarization curve), can be used for fuel-cell system components design and also for real-time applications. Real-time simulation is a key issue in many applications such as system control and hardware-in-the-loop applications. Moreover, this fuel-cell stack model is suitable and can be parameterized for all kinds of PEMFC including water-cooled and metal bipolar plates stacks: Only the cooling fluid and materials properties have to be changed.
Selfish Flow Games in Non-cooperative Multi-radio Multi-channel Wireless Mesh Networks with Imperfect Information

Multi-Radio Multi-Channel capabilities in Wireless Mesh Networks can enormously increase backhaul connectivity, network throughput and fault tolerance as simultaneous transmissions can be achieved through multiple radios tuned to non-overlapping channels with minimum degree of interference. End user flows compete for channel resources along the end to end mesh backhaul path across multiple collision domains, which need high cooperation and trust. On the other hand, realistic mesh topologies span over different collision domains with a minimum degree of cooperation among the network users. This selfish behavior of end users degrades their individual fairness and affects the overall mesh backbone performance too. In this paper, we have proposed a novel multi-radio multi-channel game theoretic model in multiple collision domains, where flows of the network are considered as players of the game. Our analytical results show that Nash Equilibrium exists for such types of games and simulation results show that our distributed algorithm converges to a stable state in finite time with maximum fairness among the players.
Modeling and power quality analysis of STATCOM using phasor dynamics

This paper deals with the modeling of synchronous static compensator (STATCOM) of a power system based on dynamic phasor model to investigate the performance of STATCOM for power quality analysis and compared with EMTP like simulation. The dynamic phasor model and EMT model of the STATCOM including the system is implemented in Matlab/Simulink toolbox and PSCAD/EMTDC, respectively. Details dynamic phasor model of STATCOM switching function and its control system has been presented. A credible solution to the power quality problems on the distribution network has been analyzed using dynamic phasor model and EMTP like PSCAD/EMTDC simulation techniques. The simulation results demonstrated that the dynamic phasor model of STATCOM including the system makes an excellent agreement with the detailed time-domain EMT model of PSCAD/EMTDC simulation. It is found that the dynamic behavior of STATCOM phasor model have very good potential application in analyzing power quality issues, faster in speed and higher accuracy as compared with PSCAD/EMTDC simulation.
Ethics, Industry, and Outcomes

Evidence-based medicine depends on research that is reliable, well conducted, and free of influence from interest groups (which are not confined to industry). There are many ways to influence the outcome of clinical research, and the history of influence in research related to tobacco is illuminating in this regard. Health care depends on industry, and if properly managed, the relationship between industry and medical academia can be symbiotic. Achieving positive outcomes from such relationships depends on ensuring the presence of the elements needed for reasonable independence on the part of investigators, and on understanding the ways in which influence can be exerted over the production and publication of evidence. Regulation cannot substitute for integrity, particularly the integrity of the investigators. Pushing the limits of ethics in research threatens to undermine not only the reputation of those conducting the research but also the standing of science itself.
Oral D‐amphetamine causes prolonged displacement of [11C]raclopride as measured by PET

Parenterally administered D‐amphetamine has been used as a challenge drug to release dopamine, which in turns inhibits [11C]raclopride binding to dopaminergic D2 receptors as measured using positron emission tomography (PET) techniques. The primary objective of this study was to determine whether orally administered D‐amphetamine would inhibit [11C]raclopride binding in a manner similar to that produced by intravenously administered D‐amphetamine. The secondary objective was to assess the timeline of these effects. Twelve healthy human volunteers participated in this study. Subjects were scanned at baseline and 2 h after D‐amphetamine administration (n = 5); at baseline, 2 and 6 h postdrug (n = 4); or at baseline, 2 and 24 h postdrug (n = 3). Orally administered D‐amphetamine caused a significant decrease in [11C]raclopride binding at 2 h (13% ± 5%). Receptor availability was still decreased at 6 h (18% ± 6%), even though physiological effects had completely returned to baseline. [11C]Raclopride binding returned to baseline at 24 h. The percentage of [11C]raclopride displacement was not correlated with plasma D‐amphetamine concentrations. In conclusion, orally administered D‐amphetamine caused a reliable and prolonged [11C]raclopride displacement, the magnitude of which is similar to that observed after intravenous administration. Possible mechanisms for the observed prolonged displacement may include persistence of intrasynaptic dopamine and/or receptor internalization. Synapse 51:27–31, 2004. © 2003 Wiley‐Liss, Inc.
Alterations of hHrd1 expression are related to hyperphosphorylated tau in the hippocampus in Alzheimer's disease

The degradation of aberrantly phosphorylated tau in neurons plays an important role in the pathogenesis of Alzheimer's disease (AD). hHrd1 is a newly identified ubiquitin ligase involved in the endoplasmic reticulum (ER)‐associated protein degradation. The expression and function of hHrd1 in AD brain remains elusive. In the present study, the expression of hHrd1 in AD hippocampus and the morphological relations between hHrd1 expression and pretangle formation were studied by using immunohistochemical single‐ and double‐labeling methods. The results showed that hHrd1 was expressed in neurons and reactive astrocytes, especially in the CA2–CA4 hippocampal subfields. The ratio of hHrd1‐positive neurons/astrocytes to total neurons/astrocytes was increased in the CA1 subfield in AD hippocampus compared with the age‐matched controls (P < 0.05). Most Alz‐50 labeled pretangles were colocalized with hHrd1, and the expression levels showed an inversed change, implied that hHrd1 might be associated with the degradation of hyperphosphorylated tau. © 2006 Wiley‐Liss, Inc.
Expanding the Knowledge Base of Resident and Facility Outcomes of Care Delivered by Advanced Practice Nurses in Long-Term Care

In 2003, a panel of nationally recognized experts in geriatric practice, education, research, public policy, and long-term care convened to examine and make recommendations about care quality and safety issues related to advanced practice nurses (APNs) in nursing home practice. This article reports on the panel recommendation that addressed expanding the evidence base of resident and facility outcomes of APN nursing home practice. A review of the small but important body of research related to nursing home APN practice suggests a positive impact on resident care and facility outcomes. Recommendations are made for critically needed research in four key areas: (a) APN nursing home practice, (b) relative value unit coding, (c) outcomes related to geropsychiatric and mental health nursing services, and (d) outcomes related to geriatric specialization. The APN role could be significantly enhanced and executed if its specific contribution to resident and facility outcomes was more clearly delineated through the recommended rigorous research.
Notoedric Mange in Western Gray Squirrels from Washington

From February 1998 to July 1999, 65 western gray squirrels (Sciurus griseus griseus) were trapped at three sites in Klickitat County, Washington (USA) as part of a home range and habitat use study. No squirrels (0/9) with mange lesions were identified in the initial trapping session (February and March 1998). During all subsequent trapping sessions (August 1998 through July 1999), squirrels with lesions consistent with notoedric mange, caused by the mite Notoedres centrifera (douglasi), were captured or recaptured at all three study sites. The diagnosis was confirmed by histopathology and examination of mites obtained from skin scrapings from two affected squirrels. Of the 56 squirrels captured from August 1998 to July 1999, 33 (59%) had characteristic mange lesions, and 14 (42%) affected squirrels died directly of mange or of secondary complications of mange. Only four breeding females of 22 radio-collared animals (males and females) in the study population were known to have survived the mange outbreak (12 died, 6 missing). Factors potentially contributing to this mange outbreak include a mast crop failure in the fall of 1998 and transmission of mites from animal to animal during trapping and processing sessions.
Hypomorphic mutation in the RAG2 gene affects dendritic cell distribution and migration

OS is a severe combined immunodeficiency characterized by erythrodermia and protracted diarrhea as a result of infiltration of oligoclonal‐activated T cells, caused by hypomorphic mutations in RAGs. The RAG2R229Q mouse model fully recapitulates the clinical OS phenotype. We evaluated whether T and B cell defects, together with the abnormal lymphoid structure, could affect DC homeostasis and function. High density of LCs was observed in skin biopsies of Omenn patients and in the derma of RAG2R229Q mice, correlating with the presence of erythrodermia. In vivo models of cutaneous skin painting and CHS demonstrated a decreased migration of RAG2R229Q DCs—in particular, LCs—into draining LNs. Interestingly, at steady state, RAG2R229Q mice showed a reduction in DC number in all hematopoietic organs except LNs. Analysis of the MHCII marker revealed a diminished expression also upon the LPS‐driven inflammatory condition. Despite the decreased number of peripheral DCs, BM pre‐cDCs were present in normal number compared with RAG2+/+ controls, whereas pDCs and monocytes were reduced significantly. Overall, these results point to a secondary defect in the DC compartment, which contributes to clinical manifestations and autoimmunity in OS.
University Startups and Entrepreneurship: New Data, New Results

This paper empirically examines commercialization of university faculty inventions through startup firms from 1994 through 2008. Using data from the Association of University Technology Managers and the 2010 NRC doctoral rankings, our research reveals several findings. We find that university entrepreneurship is more common in bad economic times and that engineering department quality and biological sciences department size are more important after the NASDAQ stock market crash in 2000. We also find that the quality of a biological sciences department is positively associated with startup company activity. Conditional on creating one startup, each additional TTO employee significantly increases university startups.
Ship Detection Using Edge-Based Segmentation and Histogram of Oriented Gradient with Ship Size Ratio

In this paper, a ship detection method is proposed; this method uses edge-based segmentation and histogram of oriented gradient (HOG) with the ship size ratio. The proposed method can prevent a marine collision accident by detecting ships at close range. Furthermore, unlike radar, the method can detect ships that have small size and absorb radio waves because it involves the use of a vision-based system. This system performs three operations. First, the foreground is separated from the background and candidates are detected using Sobel edge detection and morphological operations in the edge-based segmentation part. Second, features are extracted by employing HOG descriptors with the ship size ratio from the detected candidate. Finally, a support vector machine (SVM) verifies whether the candidates are ships. The performance of these methods is demonstrated by comparing their results with the results of other segmentation methods using eight-fold cross validation for the experimental results.