Miracle-dz/UniFAR-FTUs huggingface dataset:
Antagonistic Effect of Na+ and Mg2+ on P2z Purinoceptor‐Associated Pores in Dibutyryl Cyclic AMP‐Differentiated NG108‐15 Cells

Abstract: The effect of replacement of extracellular Na+ with N‐methyl‐d‐glucamine (NMG) on P2 receptor signaling pathways was investigated in dibutyryl cyclic AMP‐differentiated NG108‐15 cells. Benzoylbenzoic ATP (BzATP) dose‐dependently increased the cytosolic Ca2+ concentration ([Ca2+]i) with an EC50 value of 230 µM. Replacement of Na+ with NMG as well as removal of Mg2+ from the bathing buffer potentiated ethidium bromide uptake, [Ca2+]i increase, and 45Ca2+ uptake in response to ATP or BzATP. In contrast, in the presence of 5 mM Mg2+ to limit the amount of ATP4−, replacement of Na+ with NMG had no effect on the ATP‐induced [Ca2+]i increase but caused a markedly larger [Ca2+]i increase when the calculated concentration of ATP4− was >10 µM. The calculated EC50 value for ATP4− stimulation of the [Ca2+]i increase was 23 µM in NG108‐15 cells. In vascular smooth muscle cells, intracellular Ca2+ release was the major pathway for the ATP‐induced [Ca2+]i increase; both removal of Mg2+ and replacement of Na+ with NMG did not affect the action of ATP. These data suggest that ATP4−‐promoted pores are antagonized by Na+ and Mg2+ in dibutyryl cyclic AMP‐differentiated NG108‐15 cells.
Use of MT3DMS for Heat Transport Simulation of Shallow Geothermal Systems

The multi-species transport model MT3DMS is applied to simulate heat transport in shallow confined aquifers. This is done by taking advantage of the mathematical similarities between the description of heat and solute transport. A comprehensive analysis on the applicability of MT3DMS (version 5.2) for heat transport simulation of closed shallow geothermal systems is shown. MT3DMS simulations are compared with results from heat analytical solutions and with those from the established numerical code FEFLOW. Issues regarding the definition of the boundary conditions, as well as the evaluation of the type of the numerical advection solver are investigated. The computed results are examined based on residual errors. The overall agreement of MT3DMS with the analytical solutions and FEFLOW is good. Larger discrepancies are only found close to the heat source, which is due to the inherent differences of the numerical methods used by each code and the boundary conditions required by the analytical solutions. Despite these differences we find that MT3DMS can be successfully applied to simulate heat transport in saturated and confined porous media under the influence of GSHP systems.
Humped Pattern of Diversity: Fact or Artifact?

Molino and Sabatier ([1][1]) claimed to have evidence for validation of the intermediate disturbance hypothesis ([2][2]) in a tropical rainforest. Here, we demonstrate that the humped pattern of species diversity in a gradient of disturbance [figure 2 in ([1][1])] is a methodological artifact
Band Reducing Based SVM Classification Method in Hyperspectral Image Processing

In this study, a method based on image processing and machine learning is proposed for classification in hyperspectral images. The proposed method is tested on Indian Pines and KSC (Kennedy Space Center) datasets. As a preprocessing step, normalization, median filter and mean filter were applied to all bands in the hyperspectral data set. After the pre-processing, new bands are obtained by averaging the 5, 25 and 125 bands in the dataset. The obtained bands are combined and features extracted. The multi-band dataset is transformed into a single-band feature matrix. Classification is made by adding class labels to the feature matrix. SVM (Support Vector Machines) Linear, SVM Quadratic and SVM Cubic methods are used for classification using MATLAB Classification Learner Toolbox. For all the two data sets, 99% accuracy was obtained with the SVM classification algorithm.
Social Media Visual Analytics

With the development of social media (e.g. Twitter, Flickr, Foursquare, Sina Weibo, etc.), a large number of people are now using them and post microblogs, messages and multi‐media information. The everyday usage of social media results in big open social media data. The data offer fruitful information and reflect social behaviors of people. There is much visualization and visual analytics research on such data. We collect state‐of‐the‐art research and put it into three main categories: social network, spatial temporal information and text analysis. We further summarize the visual analytics pipeline for the social media, combining the above categories and supporting complex tasks. With these techniques, social media analytics can apply to multiple disciplines. We summarize the applications and public tools to further investigate the challenges and trends.
Detection and Quantification of Antibodies to Newcastle Disease Virus in Ostrich and Rhea Sera Using a Liquid Phase Blocking Enzyme-Linked Immunosorbent Assay

ABSTRACT A liquid phase blocking ELISA (LPB-ELISA) was adapted for the detection and quantification of antibodies to Newcastle disease virus. Sera from vaccinated and unvaccinated commercial flocks of ostriches (Struthio camelus) and rheas (Rhea americana) were tested. The purified and nonpurified virus used as the antigen and the capture and detector antibodies were prepared and standardized for this purpose. The hemagglutination-inhibition (HI) test was regarded as the reference method. The cutoff point for the LPB-ELISA was determined by a two-graph receiver operating characteristic analysis. The LPB-ELISA titers regressed significantly (P < 0.0001) on the HI titers with a high correlation coefficient (r = 0.875). The two tests showed good agreement (κ = 0.82; P < 0.0001), relative sensitivity (90.91%) and specificity (91.18%), and accuracy (91.02%), suggesting that they are interchangeable.
Autonomous overhead transmission line inspection robot (TI) development and demonstration

This paper describes a video submission that provides an update on the development of a robot that autonomously inspects high voltage transmission lines. The robot is being developed by the Electric Power Research Institute with collaborative partners American Electric Power, Southern Company, and Southwest Research Institute. The robot will navigate along the shield wire and will be able to perform many types of measurement along the line, bypass obstacles, and harvest power from the shield wire.
Revisiting oestrogen antagonists (clomiphene or tamoxifen) as medical empiric therapy for idiopathic male infertility: a meta‐analysis

The aim of this study was to synthesize and present the latest available evidence regarding the use of oestrogen antagonists as empiric medical therapy for idiopathic male infertility with oligo and/or asthenoteratozoospermia through meta‐analysis of randomized controlled trials (RCTs). Systematic literature acquisition was done for English and other foreign language biomedical databases up to March, 2013. RCTs relevant to the topic were identified and critically appraised independently by two physician reviewers. Dichotomous data of pregnancy rate and adverse events were extracted for calculation of odds ratio (OR) and 95% confidence interval (CI). Effect estimates were pooled using Peto method with fixed effect model. The continuous data of semen and endocrine parameters were calculated for the mean difference between pre‐ and post‐treatment effects, the weighted mean difference (WMD) and SD between the control and intervention group were determined and pooled using the random effects model. Inter‐study heterogeneity and publication bias were assessed. The Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guideline for meta‐analysis reporting was followed. Eleven RCTs of good methodological quality were included for meta‐analysis. The pooled effect estimates showed that oestrogen antagonists use was associated with a statistically significant increased pregnancy rate compared with controls (pooled OR 2.42; 95% CI 1.47–3.94; p = 0.0004). Significant increase in sperm concentration (WMD 5.24; 95% CI 2.12, 88.37; p = 0.001) and per cent sperm motility (WMD 4.55; 95% CI 0.73, 8.37; p = 0.03) were also noted. While significant elevation of serum follicle stimulating hormone (WMD 4.19 95% CI 2.05, 6.34; p = 0.0001) and testosterone (WMD 54.59; 95% CI 15.92, 93.27; p = 0.006) was associated with its use. No significant difference in adverse event was noted between oestrogen antagonists‐treated group and controls. The evidence suggests that oestrogen antagonists as empiric medical therapy for idiopathic male infertility with low non‐serious adverse event associated, may increase spontaneous pregnancy rate, improve sperm concentration and per cent sperm motility.
OCULOSTATIC AND VISUAL PHENOMENA OCCURRING IN ASSOCIATION WITH WALLENBERG'S SYNDROME

A variety of disorders related to the veslibular apparatus were found in o u r rather small series of Wallcnhcrg infarctions ( f o r refercnces, see Hjeriwr & Silftwrskiultl 1968). Links of l i t tlc knovm, po\n-crfril mochanisms arc apparently localed in the \\’rllcnl)crg area. The ocular disturbances 1n:ry initially bc3 vcry intense; and they conlinuc to be disabling in some of the cases. They are often bcwildering and difficult to analyze. Each component is rather coniplrx, and may vary in intensity during the coiirse of the examination :is well as with different positions of the head. Furthermore, the defects appear in many combinations. It \ws, however, always possible to distinguish certain patterns in the symptomatology of our patients; and, on the whole, they performed consislently when retested. A basic clinical arid post-mortem study is dcscrihed in Comment. In Ihv following report sonic of thc featurtas of our whole scrics havc been summarized in groups i n order to avoid repetition.
Fecal Transplant for Recurrent Clostridium difficile Infection in Children With and Without Inflammatory Bowel Disease

ABSTRACT Ten children at our institution received single-infusion fecal microbiome transplant (FMT) using healthy, related screened donor stool to treat recurrent Clostridium difficile infection (RCDI) via nasogastric tube (2 patients) or colonoscopic delivery. Nine of the 10 (90%) children had resolution of their symptoms after a single-infusion FMT with follow-up of 1 month to 4 years. No concerning related adverse events were recognized during short- or long-term follow-up. Three of these children had concomitant inflammatory bowel disease and 2 of these 3 (66%) patients cleared RCDI with no clinical change in their underlying inflammatory bowel disease clinical activity as assessed by Physician's Global Assessment. All of the patients who had clinical improvement of gastrointestinal symptoms of RCDI while treated with antibiotics had lasting return of baseline health after FMT.
Exploring image dependencies: a new challenge in image forensics

Though the current state of the art of image forensics permits to acquire very interesting information about image history, all the instruments developed so far focus on the analysis of single images. It is the aim of this paper to propose a new approach that moves the forensics analysis further, by considering groups of images instead of single images. The idea is to discover dependencies among a group of images representing similar or equal contents in order to construct a graph describing image relationships. Given the pronounced effect that images posted on the Web have on opinions and bias in the networked age we live in, such an analysis could be extremely useful for understanding the role of pictures in the opinion forming process. We propose a theoretical framework for the analysis of image dependencies and describe a simple system putting the theoretical principles in practice. The performance of the proposed system are evaluated on a few practical examples involving both images created and processed in a controlled way, and images downloaded from the web.
Microwave (1-100 GHz) dielectric model of leaves

A semiempirical formula for the complex dielectric permittivity of leaves from different plants is found from a comparison of published measurements covering the frequency range from 1 to 100 GHz. The explicit parameters are the dry-matter fraction m/sub d/ of the leaf and the permittivity /spl epsiv//sub SW/ of saline water with a salinity of about 1 percent. The physical part of the formula is its basis on /spl epsiv//sub SW/ while the empirical part is its linearity with m/sub d/. The formula is applicable to fresh leaves; their m/sub d/ values are in the range 0.1 >
Electronic Tandem Language Learning (eTandem): A Third Approach to Second Language Learning for the 21st Century

Tandem language learning occurs when two learners of different native languages work together to help each other learn the other language. First used in face-to-face contexts, Tandem is now increasingly being used by language-learning partners located in different countries who are linked via various forms of electronic communication, a context that has become known as eTandem. In addition to providing a brief account of the history of Tandem and eTandem, this paper provides a comprehensive overview of electronic communication media suitable for eTandem, both asynchronous and synchronous, from the telephone and email to amateur radio and business-quality videoconferencing. Finally, the Electronic Network for Language And Culture Exchange (ENLACE) is introduced, a Web-based medium through which users of Windows, Macintosh, and Unix-based computers can find language learning partners and engage in eTandem language learning using synchronous text chat alone or in combination with video and/or audio conferencing.
Cloud computing : Opportunities and issues for developing countries

Cloud computing offers a range of new opportunities for developing countries to do what they could not do earlier with computers and the Internet. Cloud computing infrastructure and applications are able to interact with users who have mobile phones, Tablet PCs, OLPC [one-laptop-per-child], and other mobile devices. This paper looks at how cloud computing will surpass the Internet in adoption and usage as this technology’s users are on the other side of the digital divide. Mobile phones and other devices have penetrated and saturated developing countries where the Internet has failed. This paper looks at the diffusion of mobile phones and devices in developing countries and its continuous dramatic rise. $15 Mobile Phones and $20 Tablet PCs are now in the hands of those technology-connectivity-deprived billions. This paper will look at how cloud computing and mobile devices combine present new opportunities for developing countries. Because the mobile phone and devices user market is too big to be ignored, cloud service providers, in collaboration, with mobile service providers have deployed hundreds of cloud-enabled applications and are continuing in their endeavour to provide an endless range of products. This paper looks at some popular mobile applications that are helping development efforts, such as m-Banking, m-Education, m-Health, m-Agriculture, and others that already exist and are popular within developing countries. Each technology has its good [opportunities], bad [challenges], and ugly [issues] side. There is an attempt to address the issues and challenges in deploying mobile applications via cloud computing in developing countries when compared to developed countries. For example, issues such as connectivity to remote regions and the challenges faced by service providers and governments to subsidise and provide mobile applications to those who are already struggling with
Fast elliptic curve cryptographic processor architecture based on three parallel GF(2/sup k/) bit level pipelined digit serial multipliers

Unusual processor architecture for elliptic curve encryption is proposed in this paper. The architecture exploits projective coordinates (x=X/Z, y=Y/Z) to convert GF(2/sup k/) division needed in elliptic point operations into several multiplication steps. The processor has three GF(2/sup k/) multipliers implemented using bit-level pipelined digit serial computation. It is shown that this results in a faster operation than using fully parallel multipliers with the added advantage of requiring less area. The proposed architecture is a serious contender for implementing data security systems based on elliptic curve cryptography.
A note on backward errors for structured linear systems

Let x̃ be a computed solution to a linear system Ax=b with , where is a proper subclass of matrices in . A structured backward error (SBE) of x̃ is defined by a measure of the minimal perturbations and such that and that the SBE can be used to distinguish the structured backward stability of the computed solution x̃. For simplicity, we may define a partial SBE of x̃ by a measure of the minimal perturbation such that Can one use the partial SBE to distinguish the structured backward stability of x̃? In this note we show that the partial SBE may be much larger than the SBE for certain structured linear systems such as symmetric Toeplitz systems, KKT systems, and dual Vandermonde systems. Besides, certain backward errors for linear least squares are discussed. Copyright © 2004 John Wiley & Sons, Ltd.
Design of a Broadband Power Amplifier Based on Power and Efficiency Contour Estimation

This letter presents the design of a broadband power amplifier (PA) that achieves, over the 0.45–3.4-GHz frequency band, an output power between 41.5 and 44.3 dBm and a power added efficiency (PAE) higher than 54%. A four-section transformer has been adopted as the output-matching network in order to target the impedance region defined by a simplified prediction of the power and efficiency contours. The designed PA can find application in flexible hardware for 5G applications, as well as in broadband radar and countermeasure systems.
Sensor Node Localization by Three Mobile Anchors in the Wireless Sensor Networks

For the deployment of sensor networks, the sensor localization, which finds the position of sensor nodes, is very important. Most previous localization schemes generally use the GPS signal for the sensor localization. However, the GPS signal is unavailable when there is an obstacle between the sensor nodes and satellites. Therefore, in this paper, we propose a new localization scheme which does not use the GPS signal. The proposed scheme localizes the sensors by using three mobile anchors. Because the three mobile anchors collaboratively move by themselves, it is self-localizable and can be adopted even when the sensors are randomly and sparsely deployed in the target field.
A reliability forecasting method for distribution systems based on support vector machine with chaotic particle swarm optimization algorithm

In this paper, support vector machine (SVM) technique is applied to predict the reliability of power distribution system. To determine the SVM models' optimal parameters for regression, particle swarm optimization algorithm is improved by combination with chaotic searching method (CPSO). The implementation approach of SVM for regression with CPSO (CPSO-SVR) is detailedly given. The CPSO-SVR models are first trained to learn the relationship between the influential factors of historical reliability and the corresponding reliability targets, and then future reliability can be predicted. In addition, a single but comprehensive index for distribution reliability is defined as IPSR. To examine the effectiveness of the proposed method, numerical experiments for the reliability forecasting of a city's power distribution system in Southern China are conducted. The results reveal that CPSO-SVR outperforms the existing with higher forecasting accuracy and more robust performance. Hence, the proposed CPSO-SVR method is a proper alternative for forecasting power distribution system reliability. Furthermore, sensitivity analyses of input influential factors are demonstrated.
Graph of civil aircraft trajectory generation and selection for weather avoidance and emission redation

In this paper it is proposed a methodology to automatically produce an adaptive graph of aircraft feasible trajectories based on which it is possible to determine the better trajectory in terms of fuel consumption, weather avoidance and emission reduction. In this contest the aircraft flight is modeled by a finite state automaton where the state is a vector describing the aircraft position, the airspeed and heading; the outputs is the fuel consumption. In the described framework, the aircraft path planning problem is formulated as the search for an optimal transition state path of the automaton which minimizes fuel consumption. The aircraft flight model is formalized, then the graph generation method is described and finally some results for different phase of flight of real aircraft are reported and compared with real flight emissions. This methodology was proposed and developed during in my PHD thesis.
MDM2 SNP309 genotype is associated with ferritin and LDH serum levels in children with stage 4 neuroblastoma

MDM2 SNP309, characterised by a T‐to‐G substitution in the MDM2 promoter, is associated with higher gene expression compared to wild type and was recently found to be a negative prognostic factor for patients with stage 4 neuroblastoma (NB), but not for children with localised disease. This polymorphism was not associated with any clinical or genetic tumour characteristics, including MYCN amplification and 1p chromosome deletion.
Do California Spotted Owls Select Nest Trees Close to Forest Edges?

SELECCIONA STRIX OCCIDENTALIS ARBOLES CERCA DE LOS BORDES DE BOSQUE PARA ANIDAR? La seleccion de los sitios de anidacion por parte de individuos de Strix occidentalis en ambientes de bosque tiene implicaciones importantes para el manejo de estas areas, particularmente si las aves seleccionan areas proximas a los bordes del bosque. Para probar la hipotesis de que S. o. occidentalis selecciona arboles de anidacion ubicados cerca de los bordes de bosques en la Sierra Nevada central, California, comparamos las distancias de 49 nidos de S. o. occidentalis con la distancia a los bordes de 49 localidades pareadas seleccionadas al azar dentro del mismo lote forestal en que se encuentran los nidos. Tambien examinamos algunas correlaciones entre estas distancias y la elevacion porque tanto el tipo de bosque como la intensidad de corte variaron con la elevacion. Encontramos que la distancia desde los arboles de anidacion hasta el borde mas proximo (media = 130 m) no difirio significativamente de las distancias d.
Monitoring of interarea oscillation mode by synchronized phasor measurement

There is a low-frequency interarea oscillation mode in middle and western 60-Hz areas of Japan. Its stability determines available transfer capacity of a tie-line. We propose a method of monitoring its stability by phasor measurements synchronized using the global positioning system. The phase angle between two places deviates randomly. However, its Fourier spectrum shows a clear peak corresponding to the interarea mode. We estimate its frequency and damping from the spectrum. The estimation results agree well with those obtained by curve fitting for large disturbances. It is also possible to estimate the eigenvector. We examine how the eigenvalue varies with the total generation and power flow in the areas.