Miracle-dz/UniFAR-FTUs huggingface dataset:
Automatic Reconstruction of Performance Indicators from Support Vector based Search Space Models in Distributed Real Power Planning Scenarios

In order to allow for a transition of the current central market and network structure of todays electricity grid to a decentralized smart grid, an efficient management of numerous distributed energy resources will become more and more indispensable. The integration of controllable but distributed and individually configured small devices entails new challenges for the design of future control structures. Pooling and joint planning are proposed concepts for future control schemes. Each energy unit may offer an individual set of feasible schedules for some future planning horizon. If a coalition of distributed energy units is supposed to plan the provision of a wanted joint real power schedule, a many-objective problem arises that demands different evaluation criteria to weight alternative schedules against each other. Each schedule causes individual costs and may be described by individual indicators like reliability, environmental impact or robustness criteria for planning. Communication and integration into planning algorithms without having to know the individual technical setting (i.e. model, operational state, or individual constraints and their modeling) of any energy unit is the aim of this paper. We propose a combination of two approaches: surrogate modeling and a decoder approach for constraint-handling that integrates indicators that are annotated to schedules. We show the appropriateness of this approach by scrutinizing the error when reconstructing the values from the black-box model.
Long-term follow-up of patients with posterior canal benign paroxysmal positional vertigo

Abstract Conclusions: Recurrence of posterior canal benign paroxysmal positional vertigo (PC-BPPV) developed in one-third of patients when followed for an average of 5 years from diagnosis. History of head trauma and Ménière's disease contributed significantly to recurrence (p < 0.05). History of head trauma as an etiologic cause was more frequent in patients with recurrence of PC-BPPV. Objectives: To estimate recurrence in the long-term follow-up of patients with PC-BPPV after successful canalith repositioning maneuvers, and to determine which factors contribute to recurrence. Methods: The charts of 118 patients with PC-BPPV were reviewed. Data of patients were recorded from the initial evaluation and treatment. Follow-up was performed at mean of 64 ± 7.7 months after the initial phase. The Dix-Hallpike maneuver was performed for diagnosis, and all patients were treated by the canalith repositioning maneuver, which was repeated every 3 days until the patients were symptom-free or results of the Dix-Hallpike maneuver were negative. Results: At diagnosis, the most common etiology was idiopathic in 55 patients (46.6%). Recurrence occurred in 39 of 118 patients (33.1%). Recurrence occurred within the first 2 years in 21 of the 39 patients (53.8%). History of head trauma was a more frequent finding in patients who developed recurrence (12 of 39, 30.8%).
The distribution of quinidine in human blood.

The uptake of quinidine by washed human red blood cells from isotonic buffer solution (pH 7.4) occurred rapidly and was proportional to the concentration of drug in buffer. A constant red cell/buffer partition ratio of 4.16+/-0.15 s.e. mean was found. 2. Uptake from buffer solution was not affected by temperature or ouabain or by gassing with nitrogen or carbon monoxide and there was no evidence of saturability. Drug in red blood cells was associated largely with the cell contents (94.4+/-1.5% s.e. mean) following partition. 3 Plasma reduced the uptake of quinidine so that a red cell/plasma partition ratio of 0.82+/-0.09 s.e. mean was found. 4 Alteration of plasma binding by dilution of plasma with buffer showed that uptake was proportional to free drug concentration. 5 The possibility of red cell uptake of drug should be included in any considerations concerning pharmacokinetic aspects of drug action in the body.
Energy Effective Congestion Control for Multicast with Network Coding in Wireless Ad Hoc Network

In order to improve network throughput and reduce energy consumption, we propose in this paper a cross-layer optimization design that is able to achieve multicast utility maximization and energy consumption minimization. The joint optimization of congestion control and power allocation is formulated to be a nonlinear nonconvex problem. Using dual decomposition, a distributed optimization algorithm is proposed to avoid the congestion by control flow rate at the source node and eliminate the bottleneck by allocating the power at the intermediate node. Simulation results show that the cross-layer algorithm can increase network performance, reduce the energy consumption of wireless nodes and prolong the network lifetime, while keeping network throughput basically unchanged.
A hybrid NRS- CART algorithm and its application on coal mine floor water-inrush prediction

With the increase of water-inrush accidents from coal mine, water-inrush prediction has become a significant aim for coal mine safety experts. As an intelligent classifying algorithm, the Classification and Regression Tree (CART) is a potential method for predicting the possibility of water inrush from coal seam floor. One of its main advantages is that the Decision Rules (DRs) can be extracted from its structure. Another is that these DRs can be used to analysis safety problems. However, the time of establishing the decision tree is too long because of the existence of the redundant information. This paper presents an effective method named NRS-CART, which is a hybrid method by combining neighborhood rough set (NRS) and classification and regression tree (CART). Moreover, the novel approach was used to detect and classify water-inrush possibilities. The experimental results showed that it only took 0.3455 seconds to predict the water-inrush possibility using the proposed method, whereas the CART spent 1.0411 seconds to predict for the same dataset, and at the same time the prediction accuracy was also improved from 88.78% to 93.90%.
Poly(dimethylsiloxane) Waveguides Integrated with Microfluidics for Absorbance Measurement

The monolithic integration of poly(dimethylsiloxane) (PDMS) waveguides with microfluidics is presented. Silicone oil is added in PDMS precursor to tune the refractive index of waveguides with air as the side and top cladding layer. Curved and straight waveguides are characterized for their insertion loss mainly due to propagation, radiation, and transition. For the integrated system, real-time absorbance measurement of fluorescein streams yields a linear response 250 muM and with a limit of detection <50 muM. The amount of stray light has been reduced with the 90deg curved waveguide configuration and shows a two-fold increase of sensitivity in the absorbance measurement as compared with straight waveguides configuration.
Phosphorelay-Regulated Degradation of the Yeast Ssk1p Response Regulator by the Ubiquitin-Proteasome System

ABSTRACT In Saccharomyces cerevisiae, a phosphorelay signal transduction pathway composed of Sln1p, Ypd1p, and Ssk1p, which are homologous to bacterial two-component signal transducers, is involved in the osmosensing mechanism. In response to high osmolarity, the phosphorelay system is inactivated and Ssk1p remains unphosphorylated. Unphosphorylated Ssk1p binds to and activates the Ssk2p mitogen-activated protein (MAP) kinase kinase kinase, which in turn activates the downstream components of the high-osmolarity glycerol response (HOG) MAP kinase cascade. Here, we report a novel inactivation mechanism for Ssk1p involving degradation by the ubiquitin-proteasome system. Degradation is regulated by the phosphotransfer from Ypd1p to Ssk1p, insofar as unphosphorylated Ssk1p is degraded more rapidly than phosphorylated Ssk1p. Ubc7p/Qri8p, an endoplasmic reticulum-associated ubiquitin-conjugating enzyme, is involved in the phosphorelay-regulated degradation of Ssk1p. In ubc7Δ cells in which the degradation is hampered, the dephosphorylation and/or inactivation process of the Hog1p MAP kinase is delayed compared with wild-type cells after the hyperosmotic treatment. Our results indicate that unphosphorylated Ssk1p is selectively degraded by the Ubc7p-dependent ubiquitin-proteasome system and that this mechanism downregulates the HOG pathway after the completion of the osmotic adaptation.
AUTOMATIC DETERMINATION OF FILTER COEFFICIENTS FOR LOCAL CONTRAST ENHANCEMENT

This study proposes an algorithm whose main advantage is in enabling the automatic determination of non-linear homomorphic filter coefficients used for local contrast enhancement in digital image processing. The presented algorithm is tested in a real production environment. The obtained results are compared with relevant examples in literature, showing the advantages of the achieved results or a relatively high level of their correspondence with reference results. The proposed procedure can be used for various applications in mechatronics, robotics and automatized production systems.
The Saint Siluan warning signs of cancer in children: Impact of education in rural South Africa

Two thirds of children with cancer never reach a specialist centre for treatment in South Africa. The majority of those who present have advanced disease. A campaign was undertaken to educate the public and the primary health workers on the Saint Siluan early warning signs of cancer in children. There was a statistically significant increase in the number of new patients referred in the 6 years following the campaign (P = 0.001), but did not succeed in achieving the referral of patients at earlier stages of disease. This list of the warning signs appears to be useful in promoting awareness of cancer. Pediatr Blood Cancer 2011;56:314–316. © 2010 Wiley‐Liss, Inc.
STUDIES OF THE GENUS CULEX LINNAEUS IN FLORIDA III. REDESCRIPTION OF THE FOURTH-STAGE LARVA OF CULEX SALINARIUS COQUILLETT AND COMPARISON WITH THAT OF CX. NIGRIPALPUS THEOBALD

ABSTRACT The larva of Culex salinarius is completely described and illustrated, except for the mouth parts, and compared with the morphologically similar larva of Cx. nigripalpus. At least 8 characters have been found to separate larvae of the two species of which 7 give 90% or higher divergence while the remaining character gives 87% separation.
Increased thymic mass and circulating naive CD4 T cells in HIV-1-infected adults treated with growth hormone

Objective To determine whether treatment with growth hormone (GH) enhances thymopoiesis in individuals infected with HIV-1. Methods Five HIV-1-infected adults were treated with GH for 6–12 months in a prospective open-label study. Immunological analyses were performed before GH treatment and repeated at 3 month intervals after GH initiation. Thymic mass was analysed using computed tomography with quantitative density and volume analysis. Analysis of circulating lymphocytes, including naive and memory T cell subsets, was performed using multiparameter flow cytometry. Results GH treatment was associated with a marked increase in thymic mass in all GH recipients. Circulating naive CD4 T cells also increased significantly in all patients during GH therapy, suggesting an enhancement of thymopoiesis. Conclusion GH has significant effects on the human immune system, including the reversal of thymic atrophy in HIV-1-infected adults. De-novo T cell production may thus be inducible in immunodeficient adults.
Nutritional Content of Mississippi Child Care Centers Participating in the Child and Adult Care Food Program: 1995 to 2019

Childhood obesity rates are increasing in the United States and the condition is more prevalent in the Southeast than in other areas of the country. Children who are obese or overweight during childhood have a much higher chance of remaining overweight throughout their lives, and the best way to combat child obesity is through influencing young children’s nutrition patterns. Many children spend a significant amount of time in childcare outside of their home, which may be responsible for providing adequate nutrition for at least two meals per day. This study evaluated the menus of Mississippi childcare centers participating in the Children and Adult Care Food Program (CACFP). Cycle menus for each center were analyzed for nutritional quality using NutriKids software. Mean daily nutrient content was calculated from one business week of menus from each center, and compared to data from a 1995 study by Oakley, Bomba, Knight, and Byrd. T-tests were used to determine the significance of the differences in the mean amounts of nutrients provided between menus from the 1995 study and the current menus. A checklist was also distributed to examine adherence to CACFP best practices and guidelines. The results showed that although the menus are still high in carbohydrates and calories from sugar, current menus were significantly lower in total and unsaturated fat, and significantly higher in iron, calcium, Vitamin C, and fiber than menus from the 1995 study. Changes in CACFP guidelines during the past twenty years may have helped centers reduce the amount of fat and increased the amount of key nutrients in menus compared to the 1995 study. While it is important to continue exploring nutritional content of childcare menus, the new CACFP guidelines may be making a positive impact.
Matrigel promotes retinoblastoma cell growth in vitro and in vivo

Cells derived from retinoblastomas grow slowly in vitro and only very rarely form tumors in nude mice. Matrigel, a mixture of components normally found in basement membranes, promotes the growth of Y‐79 and WERI‐Rbl retinoblastoma (Rb) cells when added to suspension cultures of the 2 Rb cell lines. It also substantially increases cell adhesion in vitro. Y‐79 cells, seeded into a Matrigel matrix, form round colonies over a 3‐week period similar to those of control, weakly metastatic murine melanoma cells. In vivo, s.c. co‐injection of Matrigel with either Y‐79 or WERI‐Rbl cells into nude mice promotes retino‐lastoma tumor formation. Transplantation of as few as 1,000 cells allows for xenografting under these conditions, while no tumors were observed in the absence of Matrigel, even at 10 × 106 cells/inoculum. The tumors produced have the expected morphology and express an mRNA for a highly specific retina/retinoblastoma marker protein, the interphotoreceptor retinoid‐binding protein. Thus, the xenografts obtained maintain the original morphological and molecular characteristics of the injected cells and represent a useful model for in vivo studies of retinoblastoma growth and treatment. © 1992 Wiley‐Liss, Inc.
AC-TR-17-013 December 2017 NewWidth Parameters for Model Counting

We study the parameterized complexity of the propositional model counting problem #SAT for CNF formulas. As the parameter we consider the treewidth of the following two graphs associated with CNF formulas: the consensus graph and the conflict graph. Both graphs have as vertices the clauses of the formula; in the consensus graph two clauses are adjacent if they do not contain a complementary pair of literals, while in the conflict graph two clauses are adjacent if they do contain a complementary pair of literals. We show that #SAT is fixed-parameter tractable for the treewidth of the consensus graph but W[1]-hard for the treewidth of the conflict graph. We also compare the new parameters with known parameters under which #SAT is fixed-parameter tractable.
In Vitro Susceptibility Testing of Geotrichum capitatum: Comparison of the E-Test, Disk Diffusion, and Sensititre Colorimetric Methods with the NCCLS M27-A2 Broth Microdilution Reference Method

ABSTRACT The in vitro activities of amphotericin B, flucytosine, fluconazole, itraconazole, and voriconazole against 23 isolates of Geotrichum capitatum were determined by the National Committee for Clinical Laboratory Standards (NCCLS) M27-A2 microdilution method and the Sensititre and agar diffusion methods. Amphotericin B and voriconazole appeared to be the more active drugs. Sensititre showed the highest rates of agreement with the NCCLS M27-A2 method.
Not just another multi-professional course! Part 2: Nuts and bolts of designing a transformed curriculum for multi-professional learning

Multi-professional education has traditionally aimed to develop health professionals who are able to collaborate effectively in comprehensive healthcare delivery. The respective professions learn about their differences in order to work together, rather than developing unity in their commitment to a shared vision of professionalism and service. In this, the second of two papers, the ‘nuts and bolts’ or practicalities of designing a transformed curriculum for a multi-professional course with a difference is described. Guidelines for the curriculum design process, which seeks to be innovative, grounded in theory and relevant to the learning of the students and the ultimately the health of the patients, include: valuing education; gaining buy-in; securing buy-out; defining of roles; seeking consensus; negotiating difference and expediting decisions. The phases of the design process are described, as well as the educational outcomes envisaged during the process. Reflections of the designers, in particular on what it means to be a multi-professional team, and a reconceptualization of multi-professional education are presented as challenges for educators of health professionals.
Effect of bone marrow derived mesenchymal stem cells on healing of induced full-thickness skin wounds in albino rat.

BACKGROUND AND OBJECTIVES Mesenchymal stem cells have delivered new approaches to the management of wound healing in severe skin injuries. This work was planned to evaluate the effect of bone marrow-derived mesenchymal stem cells (BMSCs) on healing of induced full thickness skin wounds in albino rats using topical & systemic injections. METHODS AND RESULTS Forty adult male albino rats were classified into 2 groups after induction of full thickness skin wound; untreated group and stem cell-treated group. The latter was further subdivided into topically and systemically treated ones. BMSCs were isolated & labeled by PKH26 before injection. Healing of wounds was evaluated grossly. Skin biopsies were obtained one & three weeks after wound induction. Sections were stained with Hematoxylin & Eosin, Masson's trichrome and immunohistochemichal stain for vascular endothelial growth factor (VEGF). Epidermal thicknesses and mean area percent of both collagen fibers & VEGF immunopositive cells were measured using image analyzer & results were subjected to statistical analysis. PKH26 fluorescent-labeled cells were found in the regenerated epidermis, hair follicles and dermis in BMSCs-treated groups. By the end of the third week, the wounds of BMSCs-treated groups showed full regeneration of epidermis, re-organization of collagen and decrease in VEGF immunopositive cells. Delayed wound healing was seen in 20% of systemically treated rats. Significant increase in the mean area percent of collagen fibers was detected in topically treated group. CONCLUSIONS Both methods of BMSCs injection were effective in healing of full thickness skin wound but topical method was more effective.
Comparison of orthopantomography and CT accuracy in predicting inferior alveolar nerve injury following lower third molar surgical extraction.

BACKGROUND The aim of this study was to compare orthopantomography (OPG) and computed tomography (CT) accuracy in predicting inferior alveolar nerve (IAN) injury after lower wisdom teeth extraction. METHODS Twenty-three patients with completely impacted lower third molars were enrolled in this study and OPG and CT exams were obtained before surgical intervention. Finally, a total of 26 lower third molars were extracted and cases of paresthesia following a IAN lesion have been registered. Then, OPG and CT images of the same patients have been randomly submitted to four experienced oral surgeons (with a seniority of at least 5 years) who were required to predict the possibility of a IAN injury by only evaluating the radiological exams. The images were anonymous and have been submitted to the surgeons without an order avoiding to influencing the answers. The agreement between the predicted and the real outcomes was statistically evaluated using the positive predictive value (PPV), the negative predictive value (NPV), Sensitivity, Specificity and the Spearman's rank correlation coefficient. RESULTS A perfect agreement between OPG-based prevision and the real development of paresthesia due to IAN injury has been observed. This agreement was only moderate when considering CT images. CONCLUSIONS OPG is a first-level diagnostic exam that provides enough information for predicting IAN lesions after impacted lower third molars surgery. CT is a second-level radiological exam that provides more information on roots morphology and on the amount of the contiguity between roots and mandibular canal resulting useful in performing a minimally invasive surgery.
Dynamic Noise Margin Analysis of a Low Voltage Swing 8T SRAM Cell for Write Operation

This paper presents the analysis of dynamic noise margin of proposed 8T static random access memory (SRAM) cell. The proposed SRAM cell has two voltage sources, one connected to the bit line and the other is connected to bitbar line. These voltage sources are used to reduce the swing voltage at the output nodes. This reduction of swing voltage causes the reduction in dynamic power dissipation of the proposed SRAM cell during switching activity. The dynamic noise margin (DNM) analysis is carried out and the results are compared with those of conventional 6T SRAM cell and existing 10T SRAM cell for different word line pulse widths. The proposed SRAM cell has higher value of DNM which ensures the higher stability than 6T and 10T SRAM cells. Simulation has been done in 65nm environment with a power supply of 1V. Microwind 3.1 is used for simulation purpose. 
Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor.

The extracellular protease urokinase is known to be crucially involved in morphogenesis, tissue repair and tumor invasion by mediating matrix degradation and cell migration. Hepatocyte growth factor/scatter factor (HGF/SF) is a secretory product of stromal fibroblasts, sharing structural motifs with enzymes of the blood clotting cascade, including a zymogen cleavage site. HGF/SF promotes motility, invasion and growth of epithelial and endothelial cells. Here we show that HGF/SF is secreted as a single‐chain biologically inactive precursor (pro‐HGF/SF), mostly found in a matrix‐associated form. Maturation of the precursor into the active alpha beta heterodimer takes place in the extracellular environment and results from a serum‐dependent proteolytic cleavage. In vitro, pro‐HGF/SF was cleaved at a single site by nanomolar concentrations of pure urokinase, generating the active mature HGF/SF heterodimer. This cleavage was prevented by specific urokinase inhibitors, such as plasminogen activator inhibitor type‐1 and protease nexin‐1, and by antibodies directed against the urokinase catalytic domain. Addition of these inhibitors to HGF/SF responsive cells prevented activation of the HGF/SF precursor. These data show that urokinase acts as a pro‐HGF/SF convertase, and suggest that some of the growth and invasive cellular responses mediated by this enzyme may involve activation of HGF/SF.