Miracle-dz/UniFAR-FTUs huggingface dataset:
The Associations of Patient Demographic Characteristics and Health Information Recall: The Mediating Role of Health Literacy

ABSTRACT We examined the mediating role of health literacy in the relationships between participant demographic characteristics and health information recall. Baseline data from two studies that focused on hypertensive adults (N = 1190; M = 62.28 years, SD = 11.98; 35.5% female; 45.9% African-American) were analyzed. The final model, which adjusted for recruitment site, indicated that financial status, race, and education were indirectly related to health information recall through health literacy. Increasing education was also directly related to better health information recall. Increasing age was not related to health literacy, but was related to poorer health information recall. The final model fit the data very well, χ2(3) = 0.69, p = . 36, RMSEA = . 000 (90% CI = .000 to .024),CFI = 1.00. The results suggest that health literacy might be one of the mechanisms underlying the relationships between participant demographic characteristics and poor health outcomes due to inaccurate recall of instructions.
A Comparison of Studies on the Quality of Life of Primary Caregivers of Stroke Survivors: A Systematic Review of the Literature

Abstract Background and Purpose: Few studies have been conducted on the quality of life (QOL) of primary caregivers of stroke survivors (with and without aphasia), with little consistency in the methods of evaluation. The purpose of this systematic review of the literature was to determine the appropriateness of study designs and instruments used to assess QOL in caregivers of stroke survivors. Method: A comprehensive literature review was conducted to identify peer-reviewed articles of caregiver’s QOL where CINAHL, MEDLINE, and PsycINFO databases were searched. Results: Nine studies that met the inclusion criteria used different QOL instruments and study designs. None of the instruments were specific to caregivers of stroke survivors. Conclusion: Future studies are warranted to assess the quality of life of caregivers of stroke survivors with and without aphasia.
Online Conflict-Free Colouring for Hypergraphs

We provide a framework for online conflict-free colouring of any hypergraph. We introduce the notion of a degenerate hypergraph, which characterizes hypergraphs that arise in geometry. We use our framework to obtain an efficient randomized online algorithm for conflict-free colouring of any k-degenerate hypergraph with n vertices. Our algorithm uses O(k log n) colours with high probability and this bound is asymptotically optimal. Moreover, our algorithm uses O(k log k log n) random bits with high probability. We introduce algorithms that are allowed to perform a few recolourings of already coloured points. We provide deterministic online conflict-free colouring algorithms for points on the line with respect to intervals and for points on the plane with respect to half-planes (or unit disks) that use O(log n) colours and perform a total of at most O(n) recolourings.
A Novel Square Dielectric Resonator Antenna With Two Unequal Inclined Slits for Wideband Circular Polarization

A novel dielectric resonator antenna (DRA) is presented for wideband circular polarization (CP). Two unequal inclined slits are loaded on the diagonal of the square DR to excite a CP mode. The effect of variation of ratio between the length of the slits on the CP and impedance characteristics is studied. The DR is excited by a proper tapered strip, connected to the input microstrip line from one side, and finally matched by a chip resistor from the lateral side. As the key parameters, the position of the excitation and matching lines and the impedance of the chip resistor are carefully optimized to adjust and improve the CP. The proposed configuration offers a relatively compact and easy-to-fabricate feeding network and multiresonant performance providing a 3-dB axial-ratio and impedance bandwidth of about (43-50)% around 3.7 GHz, gain between 4 and 6 dBi. The CP and impedance parameters of the antenna are studied, and reasonable agreement between the measured and simulated results is observed.
KNOW THE STAR, KNOW THE PLANET. III. DISCOVERY OF LATE-TYPE COMPANIONS TO TWO EXOPLANET HOST STARS

We discuss two multiple star systems that host known exoplanets: HD 2638 and 30 Ari B. Adaptive optics imagery revealed an additional stellar companion to both stars. We collected multi-epoch images of the systems with Robo-AO and the PALM-3000 adaptive optics systems at Palomar Observatory and provide relative photometry and astrometry. The astrometry indicates that the companions share common proper motion with their respective primaries. Both of the new companions have projected separations less than 30 AU from the exoplanet host star. Using the projected separations to compute orbital periods of the new stellar companions, HD 2638 has a period of 130 yr and 30 Ari B has a period of 80 yr. Previous studies have shown that the true period is most likely within a factor of three of these estimated values. The additional component to 30 Ari makes it the second confirmed quadruple system known to host an exoplanet. HD 2638 hosts a hot Jupiter and the discovery of a new companion strengthens the connection between hot Jupiters and binary stars. We place the systems on a color–magnitude diagram and derive masses for the companions which turn out to be roughly 0.5 solar mass stars.
Analyse de l’intérêt socio-économique des graines de Garcinia kola Heckel (Clusiaceae) dans la commune de Koumassi (Abidjan), Côte d’Ivoire

Garcinia kola Heckel (Clusiaceae) est une ressource vegetale forestiere perenne a multiple usages. L’alimentation et la pharmacopee africaine en constituent des usages importants. Toutefois la graine de cette plante presente une potentialite economique. A travers une enquete ethno-economique dans la commune de Koumassi (Abidjan), les composantes sociales et les caracteristiques physique et economique de la graine de G. kola ou "petit kola" ont ete analysees. Les acteurs de ce secteur sont en majorite les femmes (90%). Ils sont non scolarises ou descolarises. Ce sont des citoyens de sept (07) pays Ouest-africains avec une dominance de burkinabes (48%) suivis des ivoiriens (32%). La valeur commerciale de "petit kola" est de 1 000 XOF a 1 500 XOF par kilogramme en general. La recette journaliere obtenue est proportionnelle au volume de la vente de chaque type de commercants (detaillant, demi-grossiste, grossiste). Ces resultats sont un bon indicateur pour la gestion durable de cette ressource. © 2016 International Formulae Group. All rights reserved. Mots cles: Garcinia kola , potentialite economique, Cote d’Ivoire English Title: Analysis of the socio-economical interest of the seeds of Garcinia kola Heckel (Clusiaceae) in the commune of Koumassi (Abidjan), Cote d’Ivoire English Abstract Garcinia kola Heckel (Clusiaceae) is a perenneous forest plant resource with multiples uses. Food and African pharmacopeia constitute the main uses. However the seed of that plant species has economic potentiality. Across an ethno-economical survey in the commune of Koumassi (Abidjan), the social items and physical and economical characteristics of “bitter kola” have been assessed. Actors of this activity are essentially women (90%). They have no or under education level. They are also citizens of seven (07) West Africa countries, where the Burkinabes (48%) come first, follow by Ivorians (32%). The commercial value of “bitter kola” is about 1 000 XOF to1 500 XOF per kilogram. Daily income is proportionally to the quantity of product sell by each kind of salers (retailers, half wholesalers, wholesalers). These results are of good indicator for a sustainable use of that resource. © 2016 International Formulae Group. All rights reserved. Keywords: Garcinia kola , economic potentiality, Cote d’Ivoire
A technique enabling the controlled gene expression in targeted single cells of C. elegans

Usually, tissue specific promoters are used to examine the function of a gene of interest in vivo in transgenic lines of model organisms such as C. elegans and mice, complementing the genetic analysis with mosaic organisms. However, use of tissue specific promoters is limited by their inherent properties to drive gene expression in a restricted temporal-spatial expression pattern. It is desirable to develop techniques for regulating gene expression in a controllable way both temporally and spatially at single cell resolution. Once such techniques have been established in model organisms, they would serve as a basis for developing techniques to manipulate cellular behavior in other organisms including human. In this paper, we will first summarize previous attempts to drive gene expression at a desired time and space by using inducible promoters, in particular heat shock promoters. Then, we examine problems encountered in the previous attempts, and report our new approach to circumvent them
Altered Vaginal Microbiota Are Associated With Perinatal Mother-to-Child Transmission of HIV in African Women From Burkina Faso

Background:Mother-to-child transmission (MTCT) of HIV remains a significant problem in resource-limited settings, despite the advent of antiretroviral therapies. Because perturbations in vaginal microbial communities are associated with sexual transmission of HIV, we determined whether perinatal MTCT is associated with the vaginal microbiotas of HIV-infected mothers. Methods:We conducted a retrospective analysis of cervicovaginal microbiotas by pyrosequencing of bacterial 16S rRNA genes (median 350 sequences per sample) from 10 transmitters and 54 nontransmitters during a perinatal MTCT prevention clinical trial of azidothymidine and the microbicide benzalkonium chloride. Logistic regression was performed adjusting for multiple covariates, including CD4+ T-cell numbers and treatment group, to correlate abundances of microbial taxa with perinatal MTCT. Results:The vaginal microbiotas of these subjects were dominated by several lactobacilli species, although a subset of subjects was colonized by diverse anaerobic species. MTCT of HIV was associated with significantly greater relative abundances of several groups of microorganisms. Most notably, among the abundant bacterial species, Gardnerella vaginalis was significantly enriched in cases of antepartum transmission, compared with nontransmission (odds ratio 1.7; P = 0.004). Neither azidothymidine nor benzalkonium chloride treatment was associated with shifts in microbial distributions compared with the placebo control group. Conclusions:These data suggest that alterations in vaginal microbial communities are associated with an increased risk for perinatal MTCT, consistent with results with horizontal transmission of HIV. Therefore, determining the mucosal features associated with alterations in vaginal microbial communities may guide efforts to modulate the risk for HIV MTCT.
Comparative longitudinal study of 2 methods of scheduling maintenance visits; 2-year data.

This report compares the clinical and microbiological status of 2 groups of subjects with treated periodontis on different maintenance schedules. 43 control (C) subjects were given prophylaxes every 3 months. 40 test (T) subjects were given this service on a flexible schedule according to the proportions of spirochetes and/or motile rods in fresh smears of subgingival scrapings. Both groups were examined every 6 months clinically and microbiologically. This report presents base line, 1- and 2-year data. Generally, mean values for both groups did not differ significantly from one another. Both groups exhibited comparable increases in GI and PLI scores during the first 2 years of this study. No change in probing depth was noted between base line and the 2-year examination. However, a slight increase in attachment level, as determined by probing, was noted in both groups. Both groups also exhibited similar proportions of bacterial morphotypes at base line and subsequent examinations. Disease recurrence, defined as an increase in probing depth of 3 mm or more from base line on any tooth surface during the 2-year period, tended to be more prevalent in the C than in the T group (15/43 C and 9/40 T subjects). However, the proportional difference between the groups was not statistically significant. Subjects with disease recurrence in the T group had greater proportions of spirochetes at base line than subjects in the same group without disease recurrence (20.2% versus 9.8%, p less than 0.01). This difference in proportions persisted if both groups were examined jointly, but was only of borderline significance (16.0% versus 10.5%, p = 0.05). (ABSTRACT TRUNCATED AT 250 WORDS)
Triple Band-Notched UWB Planar Monopole Antenna Using a Modified H-Shaped Resonator

A printed microstrip-fed monopole ultra-wideband (UWB) antenna with triple notched bands is presented. By embedding a modified H-shaped resonator with an additional outer line beside the microstrip feedline, band-rejected filtering properties around the 3.5 GHz WiMAX band, the 5.2/5.8 GHz WLAN band, and the X-band satellite communication band are generated. The notched frequencies can be adjusted according to specification by altering the modified H-shaped resonator. Sharp gain reductions occur at 3.7, 5.2, 7.5, and 7.9 GHz. However, for other frequencies outside the notched bands, the gain is stable in the entire UWB band.
Expression of GAT1 in Male Reproductive System and its Effects on Reproduction in Mice

The present study was carried out to identify GABA (γ-aminobutyric acid) transport protein I (GAT1) in male reproductive organs and to study the effect of GAT1 overexpression on the male reproductive system in GAT1 transgenic mice (TG). Expression and location of GAT1 in testes, epididymis, and sperm of wild-type (WT) mice were identified by immunohistochemistry and western-blot. Histological changes of testes, epididymis, and sperm of transgenic mice overexpressing GAT1 were detected by immunofluorenscent staining and haematoxylin and eosin (HE) staining. GAT1 expression was detected in the testes, epididymis, and sperm of non-transgenic mice. Vacuolization and deformity of spermatogenic cells were observed in the transgenic mice, but the epididymis was unremarkable. Immunofluorenscent staining showed that the number of diastrophic and decapitated sperm increased significantly in transgenic mice to 46.9% from 7.3% in nontransgenic mice. These results suggest that abnormal expression of GAT1 could result in spermiogenesis function injury, sperm paramorphia and dysgenesis.
Introducing human papillomavirus vaccines—questions remain

Genital human papillomavirus (HPV) infection and HPV‐associated cervical and other anogenital cancers are significant public health problems. HPV 16 and HPV 18 are responsible for approximately 70% of all invasive cervical cancers worldwide. The first prophylactic HPV virus‐like particle (VLP) vaccine against HPV types 6/11/16/18 was licensed in 2006 for girls and women aged 9–26 years. The second prophylactic HPV vaccine against HPV types 16 and 18 has been licensed this year. These vaccines are almost 100% effective in preventing infection and high‐grade precancer associated with the HPV types included in the vaccine. The vaccines are well tolerated, safe, and highly immunogenic when given in three doses within 6 months. Efficacy of the vaccine against external vulvar and HPV‐related vaginal lesions is also high. Even though the vaccine is highly effective against high‐grade cervical, vaginal, or vulvar precancers, this only applies to women unexposed to these HPV types and only to high‐grade intraepithelial lesions caused by these HPV types. Therefore, it is important to understand that the population impact of the vaccines will be much lower than vaccinating naive populations. Implementing HPV vaccine is a great opportunity but also a great challenge. However, mandatory HPV vaccination may raise many questions, and more answers are needed.
Hydrophobically modified carboxymethyl chitosan nanoparticles targeted delivery of paclitaxel

Specific targeting of tumor cells to achieve higher drug levels in tumor tissue and to overcome the side effects is the major goal in cancer therapy. Nanoparticles encapsulating a hydrophobic core in their nanoreservoir structure were developed as a carrier for a water-insoluble drug, paclitaxel. In the present study, target-oriented nanoparticles based on biodegradable O-carboxymethyl chitosan modified with stearic acid. The surface of the nanoparticles was modified by covalent attachment of folic acid (FA) by simple carbodimide reaction to achieve tumor cell targeting property. Nanoparticles were prepared by the sonication method without involving any surfactants/emulsifiers. The nanoparticles were characterized by various state-of-the-art techniques, including laser light scattering for particles size distribution, field emission scanning electron microscopy and transmission electron microscope for surface morphology. The drug release property and the cytotoxicity of the drug loaded nanoparticles to both cancerous and noncancerous cells were evaluated in cell culture system. To our knowledge, this is the first study demonstrating a FA modified hydrophobically chitosan with paclitaxel-loaded nanoparticles targeting of folate receptor overexpressing cancer cells.
An improved equivalent circuit model of radial mode piezoelectric transformer

In this paper, both the equivalent circuit models of the radial mode and the coupled thickness vibration mode of the radial mode piezoelectric transformer are deduced, and then with the Y-parameter matrix method and the dual-port network theory, an improved equivalent circuit model for the multilayer radial mode piezoelectric transformer is established. A radial mode transformer sample is tested to verify the equivalent circuit model. The experimental results show that the model proposed in this paper is more precise than the typical model.
Effect of Flavonol Derivatives on the Carrageenin‐Induced Paw Edema in the Rat and Inhibition of Cyclooxygenase‐1 and 5‐Lipoxygenase in Vitro

Alkoxyflavonols were synthesized by the Algar‐Flynn‐Oyamada (AFO) cyclization of chalcones. Hydroxyflavonols were prepared by dealkylation of methoxyflavonols by refluxing in hydroiodic acid. The alkoxyflavonols 3‐hydroxy‐2‐(2,3,4‐trimethoxy‐phenyl)‐ 4H‐chromen‐4‐one (6), 2‐(4‐ethoxyphenyl)‐3‐hydroxy‐4H‐ chromen‐4‐one (7), 2‐(4‐butoxyphenyl)‐3‐hydroxy‐4H‐ chromen‐4‐one (10), and 2‐(3‐n‐butoxyphenyl)‐3‐hydroxy‐4H‐ chromen‐4‐one (11) as well as the trihydroxy derivative 3‐hydroxy‐ 2‐(3,4,5‐trihydroxyphenyl)‐4H‐chromen‐4‐one (18) displayed high anti‐inflammatory activity in carrageenin‐induced rat paw edema. Additionally, the inhibition of enzymes of the arachidonic acid cascade by the derivatives was investigated in vitro. In contrast to the natural compound quercetin, the com‐pounds were more potent inhibiting cyclooxygenase‐1 than 5‐lipoxygenase except for 3‐hydroxy‐7‐methoxy‐2‐(4‐methoxyphenyl)‐ 4H‐chromen‐4‐one (5). No correlation between the antiinflammatory activity in the rat paw edema test and the inhibition of 5‐lipoxygenase or cyclooxygenase‐1 could be observed. In conclusion, the present results suggest that other effects than inhibition of these enzymes of the arachidonic acid cascade are important for the anti‐inflammatory activity of the investigated alkoxyflavonols.
Decentralized control based on modified fuzzy disturbance observer for interconnected nonlinear system

In this paper, a decentralized control based on modified fuzzy disturbance observer for interconnected nonlinear system is developed under the interaction and the internal/external disturbances and both. The performance of modified fuzzy disturbance observer (MFDO) is improved by considering the disturbance reconstruction error which consists of minimum approximation error and optimal parameter error. To adjust the parameters of the MFDO, two tuning methods are proposed by means of Lyapunov stability theorem. One employs only the disturbance observation error for adaptation law to guarantee that the MFDO monitors the disturbance. The other adopts the augmented error to achieve control objective as well. Finally, computer simulation results are illustrated to demonstrate the effectiveness of the MFDO in this paper.
Estudio longitudinal y caracterización cognitiva de portadores de la mutación C.709-1G>A en el gen de la Progranulina

La Demencia Frontotemporal (DFT) engloba a un grupo de enfermedades neurodegenerativas clinica y neuropatologicamente heterogeneas, que afectan a los lobulosfrontales y temporales, y cuyos sintomas principales son alteraciones en la conducta, y en ellenguaje con una relativa preservacion de la memoria.La historia familiar positiva se presenta en el 25-50% de los casos. En el ano 2006 seidentifico la Granulina (GRN) como segundo gen relacionado con DFT, situado en el cromosoma17, con mutaciones en GRN responsables de un importante numero de casos con DFT familiar.En el ano 2008 se describieron las manifestaciones clinicas de una serie de familias del PaisVasco con la mutacion c.709-1G>A en GRN (de Munain et al., 2008). El trabajo que se presenta en esta tesis esta dividido en tres estudios cuyo objetivoprincipal es la caracterizacion cognitiva de portadores asintomaticos de la mutacion c.709-1G>Aen GRN y la identificacion de rasgos cognitivos alterados en una posible fase preclinica.El primer estudio fue un estudio transversal con una muestra de 13 portadoresasintomaticos y de 19 no portadores. Los resultados mostraron diferencias entre los grupos enel dominio de atencion y en una prueba de lenguaje. Por otro lado, en el grupo de portadores, laedad correlacionaba con un peor rendimiento en un mayor numero de pruebasneuropsicologicas y ademas esta relacion era de mayor intensidad que en el grupo de noportadores.El segundo estudio fue un estudio de neuroimagen cuyos objetivos eran analizarcambios en el grosor cortical dependiendo de la condicion de portadores de la mutacion c.709-1G>A y de no portadores y correlacionar estos cambios con las medidas cognitivas. Losresultados revelaron una disminucion del grosor cortical en el lobulo temporal en relacion conla edad en los portadores de la mutacion.El tercer estudio consistio en un estudio longitudinal en tres visitas espaciadas en dosanos cada una de ellas. Para este estudio se conto con una muestra inicial de 15 portadoresasintomaticos y 25 no portadores. Los resultados en la comparacion entre visitas confirmaron laexistencia de diferencias en atencion y flexibilidad cognitiva. El seguimiento temporal mostroun declinar marcado en el reconocimiento de emociones en el grupo de portadores. En elseguimiento individual se identificaron a 4 portadores en rangos de Deterioro CognitivoAsintomatico.Estudio longitudinal y caracterizacion cognitiva de portadores de la mutacion c . 7 0 9 -1 G >A en el gen de laProgranulina.Los resultados de esta tesis confirman la existencia de diferencias cognitivas entreportadores y no portadores y confirman la existencia de una fase preclinica cognitiva conafectacion principal del reconocimiento de emociones.