Miracle-dz/UniFAR-FTUs huggingface dataset:
A Sequential Sentence Paradigm Using Revised PRESTO Sentence Lists.

BACKGROUND Listening in challenging situations requires explicit cognitive resources to decode and process speech. Traditional speech recognition tests are limited in documenting this cognitive effort, which may differ greatly between individuals or listening conditions despite similar scores. A sequential sentence paradigm was designed to be more sensitive to individual differences in demands on verbal processing during speech recognition. PURPOSE The purpose of this study was to establish the feasibility, validity, and equivalency of test materials in the sequential sentence paradigm as well as to evaluate the effects of masker type, signal-to-noise ratio (SNR), and working memory (WM) capacity on performance in the task. RESEARCH DESIGN Listeners heard a pair of sentences and repeated aloud the second sentence (immediate recall) and then wrote down the first sentence (delayed recall). Sentence lists were from the Perceptually Robust English Sentence Test Open-set (PRESTO) test. In experiment I, listeners completed a traditional speech recognition task. In experiment II, listeners completed the sequential sentence task at one SNR. In experiment III, the masker type (steady noise versus multitalker babble) and SNR were varied to demonstrate the effects of WM as the speech material increased in difficulty. STUDY SAMPLE Young, normal-hearing adults (total n = 53) from the Purdue University community completed one of the three experiments. DATA COLLECTION AND ANALYSIS Keyword scoring of the PRESTO lists was completed for both the immediate- and delayed-recall sentences. The Verbal Letter Monitoring task, a test of WM, was used to separate listeners into a low-WM or high-WM group. RESULTS Experiment I indicated that mean recognition on the single-sentence task was highly variable between the original PRESTO lists. Modest rearrangement of the sentences yielded 18 statistically equivalent lists (mean recognition = 65.0%, range = 64.4-65.7%), which were used in the sequential sentence task in experiment II. In the new test paradigm, recognition of the immediate-recall sentences was not statistically different from the single-sentence task, indicating that there were no cognitive load effects from the delayed-recall sentences. Finally, experiment III indicated that multitalker babble was equally detrimental compared to steady-state noise for immediate recall of sentences for both low- and high-WM groups. On the other hand, delayed recall of sentences in multitalker babble was disproportionately more difficult for the low-WM group compared with the high-WM group. CONCLUSIONS The sequential sentence paradigm is a feasible test format with mostly equivalent lists. Future studies using this paradigm may need to consider individual differences in WM to see the full range of effects across different conditions. Possible applications include testing the efficacy of various signal-processing techniques in clinical populations.
Simulating real-life exposures to uncover possible risks to human health: A proposed consensus for a novel methodological approach

In real life, consumers are exposed to complex mixtures of chemicals via food, water and commercial products consumption. Since risk assessment usually focuses on individual compounds, the current regulatory approach doesn’t assess the overall risk of chemicals present in a mixture. This study will evaluate the cumulative toxicity of mixtures of different classes of pesticides and mixtures of different classes of pesticides together with food additives (FAs) and common consumer product chemicals using realistic doses after long-term exposure. Groups of Sprague Dawley (CD-SD) rats (20 males and 20 females) will be treated with mixtures of pesticides or mixtures of pesticides together with FAs and common consumer product chemicals in 0.0, 0.25 × acceptable daily intake (ADI)/tolerable daily intake (TDI), ADI/TDI and 5 × ADI/TDI doses for 104 weeks. All animals will be examined every day for signs of morbidity and mortality. Clinical chemistry hematological parameters, serum hormone levels, biomarkers of oxidative stress, cardiotoxicity, genotoxicity, urinalysis and echocardiographic tests will be assessed periodically at 6 month intervals. At 3-month intervals, ophthalmological examination, test for sensory reactivity to different types of stimuli, together with assessment of learning abilities and memory performance of the adult and ageing animals will be conducted. After 24 months, animals will be necropsied, and internal organs will be histopathologically examined. If the hypothesis of an increased risk or a new hazard not currently identified from cumulative exposure to multiple chemicals was observed, this will provide further information to public authorities and research communities supporting the need of replacing current single-compound risk assessment by a more robust cumulative risk assessment paradigm.
Estimation Considerations in Contextual Bandits

Contextual bandit algorithms seek to learn a personalized treatment assignment policy, balancing exploration against exploitation. Although a number of algorithms have been proposed, there is little guidance available for applied researchers to select among various approaches. Motivated by the econometrics and statistics literatures on causal effects estimation, we study a new consideration to the exploration vs. exploitation framework, which is that the way exploration is conducted in the present may contribute to the bias and variance in the potential outcome model estimation in subsequent stages of learning. We leverage parametric and non-parametric statistical estimation methods and causal effect estimation methods in order to propose new contextual bandit designs. Through a variety of simulations, we show how alternative design choices impact the learning performance and provide insights on why we observe these effects.
Dimethylsulphide (DMS) emissions from the western Pacific Ocean: a potential marine source for stratospheric sulphur?

Abstract. Sea surface and atmospheric measurements of dimethylsulphide (DMS) were performed during the TransBrom cruise in the western Pacific Ocean between Japan and Australia in October 2009. Air–sea DMS fluxes were computed between 0 and 30 μmol m−2 d−1, which are in agreement with those computed by the current climatology, and peak emissions of marine DMS into the atmosphere were found during the occurrence of tropical storm systems. Atmospheric variability in DMS, however, did not follow that of the computed fluxes and was more related to atmospheric transport processes. The computed emissions were used as input fields for the Lagrangian dispersion model FLEXPART, which was set up with actual meteorological fields from ERA-Interim data and different chemical lifetimes of DMS. A comparison with aircraft in situ data from the adjacent HIPPO2 campaign revealed an overall good agreement between modelled versus observed DMS profiles over the tropical western Pacific Ocean. Based on observed DMS emissions and meteorological fields along the cruise track, the model projected that up to 30 g S per month in the form of DMS, emitted from an area of 6 × 104 m2, can be transported above 17 km. This surprisingly large DMS entrainment into the stratosphere is disproportionate to the regional extent of the area of emissions and mainly due to the high convective activity in this region as simulated by the transport model. Thus, if DMS can cross the tropical tropopause layer (TTL), we suggest that the considerably larger area of the tropical western Pacific Ocean can be a source of sulphur to the stratosphere, which has not been considered as yet.
Mapping senses in BabelNet to Chinese based on word embedding

Along with language evolution, different languages have formed self-contained concept architecture. The same concept may be described with different semantic relations in different languages. The mismatch among concepts hinders synergetic construction of language resources. Since the concepts are identical in nature, if they could be aligned, the concept architecture of different language would complement with each other. Aiming at the problem, this paper proposes a method to automatically align the concepts in different languages based on the sentence embedding with the help of a bilingual dictionary. Firstly, a word embedding is trained on a monolingual corpus; Secondly, based on the word embedding, the sentence embedding of concept definition and examples are generated; Thirdly, for each concept in the target language, its similarity with candidate concepts in the source language are computed based on the sentence embedding; Then, it would be aligned to the concept in the source language with the maximum similarity. We have developed a test dataset to evaluate our methods. The experiment on the dataset has demonstrated the best performance of our method, which has achieved 75.75% in F1-measure.
Positive Change After Severe Burn Injuries

Aims of the study were to examine positive change in people with severe burn injuries and to examine the impact of related constructs, demographic and medical variables on Post Traumatic Growth (PTG). A total of 149 participants who had been treated for a severe burn injury completed the posttraumatic growth inventory as well as other self-report inventories assessing coping, social support, quality of life, and mental distress. Similar to other populations who experienced trauma and adversity, burn survivors also report PTG. The strongest predictors for PTG were active coping and social support. Gender and age differences were found in the current study. Implications for further research and interventions facilitating PTG are discussed.
Dose-ranging pilot randomized trial of amino acid mixture combined with physical activity promotion for reducing abdominal fat in overweight adults

Objective The objective of this study was to determine the effective dose of an amino acid mixture comprising arginine, alanine, and phenylalanine combined with physical activity promotion in reducing abdominal fat among overweight adults. Methods A 12-week randomized, double-blind, placebo-controlled, dose-ranging, pilot trial was conducted in Mito, Japan, from January through April 2016, and the data were analyzed from May through November 2016. The study participants were 35 overweight adults, aged 20–64 years, with no regular exercise habit. Participants were randomly assigned to high-dose (3,000 mg/d, n=9), medium-dose (1,500 mg/d, n=9), low-dose (750 mg/d, n=8), or placebo (0 mg/d, n=9) groups, and the test beverage containing the amino acid mixture or placebo was administered for 12 weeks. All participants maintained a physically active lifestyle during the study period through monthly physical activity promotion sessions and smartphone-based self-monitoring with wearable trackers. Primary outcomes were changes in abdominal total, subcutaneous, and visceral fat areas, assessed by computed tomography. Results Of the 35 enrolled participants, 32 completed the 12-week follow-up visit. The intention-to-treat analysis revealed that the changes in abdominal total fat area were −14.6 cm2 (95% confidence interval [CI], −39.6 cm2 to 10.4 cm2), −25.3 cm2 (95% CI, −71.0 cm2 to 20.3 cm2), −23.2 cm2 (95% CI, −48.0 cm2 to 1.6 cm2), and −12.5 cm2 (95% CI, −29.1 cm2 to 4.0 cm2) in the high-dose, medium-dose, low-dose, and placebo groups, respectively. Similar results were obtained for visceral and subcutaneous fat areas. No study-related adverse events were reported. Conclusion Compared with placebo, a medium or low dose of the amino acid mixture may facilitate abdominal fat reduction among overweight adults. A larger randomized trial with sufficient statistical power should be implemented to validate the effectiveness of this supplement.
Development of an interlaced-crossfiring geometry for proton grid therapy

Abstract Background: Grid therapy has in the past normally been performed with single field photon-beam grids. In this work, we evaluated a method to deliver grid therapy based on interlacing and crossfiring grids of mm-wide proton beamlets over a target volume, by Monte Carlo simulations. Material and methods: Dose profiles for single mm-wide proton beamlets (1, 2 and 3 mm FWHM) in water were simulated with the Monte Carlo code TOPAS. Thereafter, grids of proton beamlets were directed toward a cubic target volume, located at the center of a water tank. The aim was to deliver a nearly homogeneous dose to the target, while creating high dose heterogeneity in the normal tissue, i.e., high gradients between valley and peak doses in the grids, down to the close vicinity of the target. Results: The relative increase of the beam width with depth was largest for the smallest beams (+6.9 mm for 1 mm wide and 150 MeV proton beamlets). Satisfying dose coverage of the cubic target volume (σ < ±5%) was obtained with the interlaced-crossfiring setup, while keeping the grid pattern of the dose distribution down to the target (valley-to-peak dose ratio <0.5 less than 1 cm before the target). Center-to-center distances around 7–8 mm between the beams were found to give the best compromise between target dose homogeneity and low peak doses outside of the target. Conclusions: A nearly homogeneous dose distribution can be obtained in a target volume by crossfiring grids of mm-wide proton-beamlets, while maintaining the grid pattern of the dose distribution at large depths in the normal tissue, close to the target volume. We expect that the use of this method will increase the tumor control probability and improve the normal tissue sparing in grid therapy.
A Real-Time PCR Assay for the Separation of Autographa gamma (Noctuidae: Plusiinae) From Morphologically Similar Species in North America

Abstract The silverY moth, Autographa gamma L. (Noctuidae: Plusiinae), is a pest of major economic importance in its native range of Europe, Asia, and North Africa. Although not present in North America, larvae of A. gamma are commonly intercepted in commodity shipments at U.S. ports, and adult surveys are conducted each year in more than 20 states. Because of the similarity of A. gamma to several native North American species that are attracted to the same pheromone lure, morphological identification of adults is difficult and requires dissection. In 2010, a specimen of Autographa californica (Speyer, 1875) (Lepidoptera: Noctuidae) from Pennsylvania was incorrectly identified as A. gamma, signaling the need for an alternative method of rapid identification. Here we detail a real-time PCR assay capable of identifying A. gamma specimens in approximately 45 min using extracted DNA. The assay uses a hydrolysis probe that targets a species-specific segment of the CO1 DNA barcode region, while a control probe targets a conserved region of 18S rDNA. The assay was tested with two independent runs of 452 specimens of Plusiinae representing 23 different species. The assay provided unambiguous data 99.7% of the time and did not result in any false positives; these data were used to develop a rule set for interpreting the real-time PCR results. In addition, the same diagnostic probe was tested in bulk sample simulations using real-time PCR and droplet digital PCR where A. gamma could be detected in concentrations as low as 1:1,000,000 (gamma:californica). These experiments provide baseline data for developing a bulk sample assay.
Community Developmental Assets and Positive Youth Development: The Role of Natural Mentors

This study investigates the role of mentoring relationships in explaining associations between youth experiences of community developmental assets (i.e., involvement in structured activities and community attitudes towards youth) and youth outcomes within a national sample of 15-year-olds (n = 1,860). Results indicated that community assets were associated with having a mentor, and that youth perceptions of community attitudes towards youth were associated with higher quality mentoring relationships. Having a mentor significantly mediated the association between community assets and prosocial values. Likewise, mentoring relationship quality mediated the association between community attitudes towards youth and school engagement, mastery, prosocial values, and purpose.
Physical activity and quality of life in older adults: Influence of health status and self-efficacy

Background: Physical activity has been positively linked to quality of life (QOL) in older adults. Measures of health status and global well-being represent common methods of assessing QOL outcomes, yet little has been done to determine the nature of the relationship of these outcomes with physical activity.Purpose: We examined the roles played by physical activity, health status, and self-efficacy in global QOL (satisfaction with life) in a sample of older Black and White women.Method: Participants (N = 249, M age = 68.12 years) completed multiple indicators of physical activity, self-efficacy, health status, and QOL at baseline of a 24-month prospective trial. Structural equation modeling examined the fit of 3 models of the physical activity and QOL relationship.Results: Analyses indicated that relationships between physical activity and QOL, self-efficacy and QOL were all indirect. Specifically, physical activity influenced self-efficacy and QOL through physical and mental health status, which in turn influenced global QOL.Conclusions: Our findings support a social cognitives model of physical activity’s relationship with QOL. Subsequent tests of hypothesized relationships across time are recommended.
Three-dimensional microfluidic devices fabricated in layered paper and tape

This article describes a method for fabricating 3D microfluidic devices by stacking layers of patterned paper and double-sided adhesive tape. Paper-based 3D microfluidic devices have capabilities in microfluidics that are difficult to achieve using conventional open-channel microsystems made from glass or polymers. In particular, 3D paper-based devices wick fluids and distribute microliter volumes of samples from single inlet points into arrays of detection zones (with numbers up to thousands). This capability makes it possible to carry out a range of new analytical protocols simply and inexpensively (all on a piece of paper) without external pumps. We demonstrate a prototype 3D device that tests 4 different samples for up to 4 different analytes and displays the results of the assays in a side-by-side configuration for easy comparison. Three-dimensional paper-based microfluidic devices are especially appropriate for use in distributed healthcare in the developing world and in environmental monitoring and water analysis.
Gender and acculturation influences on physical activity in latino adults

Background: Studies examining physical activity levels have used samples primarily composed of non-Latino Whites and have focused on leisure time physical activity (LTPA). Additionally, few studies have investigated differences in physical activity between Latino men and Latina women, or the relationship between acculturation and activity.Purpose: To examine the subjective and objective physical activity of Latinos and gender differences in physical activity and the extent to which LTPA and non-LTPA were predictive of overall accelerometer physical activity. An additional objective was to examine the relationship between acculturation and different types of physical activity.Methods: Data were obtained from 155 Latinos (n = 86 female, n = 69 male). Comparisons were made between Latino men and women.Results: Latino men participated in significantly greater occupational and overall objective and subjective physical activity than Latina women; however, women participated in greater household activity. Regression analyses demonstrated that recreational, occupational, and household activity were significant predictors of overall accelerometer physical activity for the complete sample. Among women, recreational and household activity were significant predictors; however, overall accelerometer physical activity was not significantly predicted in men. Additionally, it was demonstrated that acculturation was related to occupational activity, but not to recreational activity.Conclusions: These results suggest that gender differences in physical activity are present among Latinos and that acculturation may be a correlate of various types of physical activity.
PCAR: A power controlled routing protocol for wireless ad hoc networks

Power control and routing are two fundamental supporting techniques for wireless communications in ad hoc networks. However, most existing power control and routing proposals are not really efficient enough, due to separate considerations on them. In this paper, motivated by the observation on the necessity and feasibility of the combination of power control and routing, we propose a power controlled routing protocol PCAR (Power Controlled Ad hoc Routing). The basic idea is to develop power control on top of the distance-vector routing mechanism that is based on the classical distributed Bellman-Ford algorithm. Each node adjusts the transmission power automatically through the PIPC (Proportion-Integral Power Control) algorithm that we previously proposed. Both theoretical analysis and simulation results show that PCAR has a good performance.
Toxicity of Three Acaricides to the Predatory Mite, Neoseiulus bicaudus (Acari: Phytoseiidae) and Their Impact on the Functional Response to Tetranychus turkestani (Acari: Tetranychidae)

Abstract The use of chemical pesticides particularly acaricides can reduce the control efficacy of natural enemies. The objectives of this study were 1) to evaluate the toxicity of three acaricides to the phytoseiid mite Neoseiulus bicaudus (Acari: Phytoseiidae) by spraying acaricides on N. bicaudus adult females and 2) to determine the effect of these acaricides on the functional response of different stages of N. bicaudus to the prey Tetranychus turkestani Ugarov & Nikolski (Acari: Tetranychidae). The results indicated that the survivability of N. bicaudus differed among the three acaricides tested. Pyridaben exhibited the highest toxicity to N. bicaudus not only because it caused higher mortality but also because it reduced the peak consumption for adults and increased the peak consumption for deutonymphs of N. bicaudus. The two other acaricides, azocyclotin and bifenazate, also slightly reduced the peak consumption, but not significantly, and the overall functional response was not different from control, untreated predatory mites. Bifenazate (143–4,300 mg a.i./liter) was relatively nontoxic to N. bicaudus (less than 10% mortality) but highly toxic to T. turkestani (more than 95% mortality). Accordingly, bifenazate is the most suitable for maintaining N. bicaudus in the field. Combining bifenazate and azocyclotin with N. bicaudus is a possible strategy for T. turkestani management.
Self-adjusting microstructures (SAMS)

Composite LPCVD polysilicon/silicon nitride flexures have been fabricated on the sidewalls of previously patterned polysilicon mesas by anisotropic reactive-ion etching. Cantilever beams 450 nm thick (150 nm of silicon nitride and 300 nm of polysilicon) and 2.5 mu m wide (the mesa height) were fabricated. Upon release from the sidewall, the cantilever deflects laterally away from the mesa due to a large built-in bending moment arising from the compressive residual stress in the polysilicon layer and the tensile residual stress in the silicon nitride layer. End deflections of about 20 mu m are observed for 70 mu m-long cantilevers. This self-adjusting microstructure (SAMS) makes use of residual stresses in thin films to reduce intercomponent clearances or to apply preloads in micromechanical systems. The authors present a design theory for SAMS, describe the fabrication process in detail, and discuss the results of initial experiments. <<ETX>>