Miracle-dz/UniFAR-FTUs huggingface dataset:
On Separability of Fuzzy Relations

The problem of separability veriﬁcation of fuzzy binary relations is considered. A necessary and sufﬁcient condition for separability is given and an efﬁcient algorithm for checking separability that can be easily applied in practice is suggested. The paper is supplemented by a simple test that sometimes might be helpful in detecting non-separability just at one glance
Simplified metrics for the identification of the Madden–Julian oscillation in models

We propose simplified metrics to evaluate the fidelity with which the Madden–Julian oscillation (MJO) is simulated in climate models. These metrics are based on lag correlation analysis of principal component time series (PCs). The PCs are obtained by projecting simulated 20–100 day bandpass filtered daily outgoing longwave radiation onto the two leading empirical orthogonal functions of observed MJO variability. The simplified MJO metrics, the maximum positive correlation and time lag at which it occurs, provide consistent information relative to more complex diagnostics developed by the Madden–Julian Oscillation Working Group (CLIVAR MJOWG) and by Kim et al. Copyright © 2012 Royal Meteorological Society
THE CHEMOADJUVANT POTENTIAL OF PERGULARIA DAEMIA (FORSK.) ON EXPRESSION PATTERN IN EXPERIMENTAL ORAL CARCINOGENESIS

Abstract Pergularia daemia (Family: Asclepiadaceae), is a perennial herb growing widely along the road sides of India. Traditionally, the plant is utilized in many disease conditions. These findings provide valuable information that might help in the selection of possible biomarkers that can be used in early detection of the alarming problem of oral cancer in Southeast Asia. Topical application of DMBA for 14 weeks induced buccal pouch tumours that showed aberrant expression of cytokeratins, a marker for epithelial carcinomas. This was associated with increased cell proliferation and evasion of apoptosis as revealed by upregulation of proliferating cell nuclear antigen, NF-κB, mutant p53, Bcl-2 and downregulation of Bax and caspase 3 protein expression. Our findings clearly suggest that PDME may play a role as a novel chemopreventive or therapeutic agent for oral carcinogenesis. Key words : Pergularia daemia , Chemoadjuvant, RT-PCR, Western Blotting
Growth Hormone Treatment Does Not Alter Lower Limb Asymmetry in Children with Russell-Silver Syndrome

Background: Growth hormone (GH) treatment has been proven to have a beneficial effect on growth in children with Russell-Silver syndrome (RSS). Methods: We describe 7 prepubertal children with RSS and lower limb asymmetry treated with GH for 3 years. Results: There was a significant increase in height without any significant change in the asymmetry. Conclusions: We conclude that the rapid growth acceleration to GH treatment does not alter the lower limb asymmetry in children with RSS.
High Gain (30 dB) and High Saturation Power (11 dBm) RSOA Devices as Colorless ONU Sources in Long-Reach Hybrid WDM/TDM-PON Architecture

We propose a hybrid wavelength-division-multi-plexing/time-division-multiplexing architecture using reflective semiconductor optical amplifiers (RSOAs) for next-generation access solutions. We demonstrate that the use of a high gain and high output power RSOA as remote modulator enables a 36-dB optical budget for colorless operation at 2.5 Gb/s over 45-km single-mode fiber. This RSOA-based configuration provides a reasonable cost per user for this hybrid system and can be easily upgraded.
Session Aware Music Recommendation System with Matrix Factorization technique-SVD

- Recommender systems (RS) serve as valuable information filtering tools for web online users to deal with huge amount of information available on the Internet. RS can be used in making decision in various fields like which books to purchase or which music to listen and so on. In this paper we have proposed and implemented an algorithm based on the Collaborative filtering method and Matrix Factorization technique -SVD. Collaborative filtering is one of the traditional method for Recommendation Systems based on the user feedback. Matrix factorization is a method to address the problem of Sparsity. In this paper , first sessions are formed based on the timestamps of user logs. Collaborative filtering is used to form clusters based on users and items. SVD is applied for the user-item matrix formed from the clusters to address the Sparsity problem. Finally recommendations are given to the new test users by using user and item clusters. Experiments are performed on the benchmark data set for the proposed algorithm and results shows improvement of the recommendation system accuracy over traditional collaborative filtering method.
The Role of Fludrocortisone in Cognition and Mood in Patients with Primary Adrenal Insufficiency (Addison's Disease)

Background: Primary adrenal insufficiency (AI) requires hormone replacement therapy with fludrocortisone and hydrocortisone stimulating glucocorticoid (GR) and mineralocorticoid receptors (MR). Evidence from animal and human studies shows that MR function is crucial for cognitive function and mood. Regarding patients with AI, very little is known about the role of MR in cognitive function and mood. Methods: A repeated-measures within-subject design was used to determine whether cognitive function and mood are related to MR occupation in patients with AI. Intraindividually, patients were examined twice, with 1 week between testing days: once with fludrocortisone (high MR occupation) and once without fludrocortisone (low MR occupation). All patients kept their stable regimen of hydrocortisone. The assessment of cognitive function included executive function, attention, and verbal, visuospatial and working memory. Additionally, mood and blood pressure were measured. Results: Verbal memory improved significantly during high MR occupation (after fludrocortisone intake) compared to low MR occupation [without fludrocortisone, t(29) = -2.1, p = 0.046]. There were trend level differences in the Number-Combination test [t(29) = -1.9, p = 0.074] and in the Stroop interference task [t(29) = -1.9, p = 0.068]. No significant differences in visuospatial and working memory were found. Furthermore, the current mood state was better during high MR occupation compared to low MR occupation [t(29) = -2.4, p = 0.023] as was diastolic blood pressure [F(2, 29) = 3.6, p = 0.07]. Conclusions: Cognitive function and mood in patients with AI depend in part on MR occupation. Because the medium effect size indicates a potential clinical significance, further studies should systematically examine which dosages of fludrocortisone are associated with optimal cognitive function and mood in AI patients.
Aneuploidy in human oocytes: nondisjunction or predivision?

ABC Fax + 41 61 306 12 34 E-mail karger@karger.ch www.karger. com © 2002 S. Karger AG, Basel 0301–0171/01/0944–0241$17.50/0 Accessible online at: www.karger. com/journals/ccg Human oocytes arrested at metaphase II and remaining unfertilized in programs of assisted reproduction can be analyzed to elucidate the incidence of chromosomal abnormalities arising during first meiotic division (for review see EichenlaubRitter, 1998). One of the most remarkable findings in this field is the fact that the concept of maternal aneuploidy-causing mechanisms had to be revised. Apart from a presumed anaphase lag in some cases of hypohaploidy, deviations from the normal haploid count had been exclusively attributed to nondisjunction of bivalents until Angell (1991) emphasized the role of predivision. In her studies, there were no metaphases with additional whole chromosomes, thus questioning the relevance of nondisjunction for producing trisomic conceptions. Instead, single chromatids, defined as resulting from a precocious division of the centromere during anaphase I, constituted the only abnormality (Angell, 1997). Other investigators, however, provided evidence for the existence of both mechanisms (Kamiguchi et al., 1993; Márquez et al., 1998; Nakaoka et al., 1998). We have recently suggested a uniform nomenclature for oocytes with predivided chromosomes (Rosenbusch and Schneider, 2000) and, whilst reviewing the literature, noted that there is no survey of the distribution of nondisjunction and predivision in aneuploid cells. This prompted us to compile relevant data which include direct analyses of the oocyte chromosomes and indirect conclusions on the oocyte karyotype by investigation of the first polar body (PB). The information obtained from these two sources turned out highly contradictory. Data collection and definitions
Paving the path for high data rates by GERAN evolution EDGE2 with dual-carrier

The introduction of the upcoming GERAN evolution feature package in current GSM/EDGE deployments offers operators significant boost in network capacity and mobile data users UMTS/HSPA like high speed packet data services along with competitive latency. Intelligent radio resource management supports novel dual-carrier capable mobile stations by dynamic configuration of GPRS/EDGE packet data channels (PDCHs) on multiple non-BCCH carriers. In addition the currently standardized EDGE2 level B (EDGE2-B) concept provides enhanced PDCH data rates up to 118.4 kbps per timeslot. In this paper system level simulation results for the end-to-end performance of GERAN over TCP/IP are presented assuming conventional 4 timeslots up to future potential 14 timeslots capable EDGE and EDGE2-B mobiles showing up to 800 / 1600 kbps peak data rates. FTP-application throughput has been investigated with respect to both download file size and important TCP settings such as e.g. receiver window size. The GERAN dual-carrier performance has been evaluated for EDGE and EDGE2-B both under ideal radio conditions and in regular hexagonal cellular deployments depending on system load, exemplifying FTP 500 kbyte download with 8 timeslots capable mobiles. At medium system load EDGE2-B compared to EDGE reveals about 100% capacity gain and more than 60% gain in mean user throughput.
Electric field induced fluid flow on microelectrodes : the effect of illumination

The electrokinetic manipulation of particles suspended in a fluid medium is accomplished using microelectrodes that generate non-uniform fields of significant strength from low applied potentials. The high strength fields produce not only forces on the particles but also on the fluid medium used for suspension. This paper presents qualitative and semi-quantitative observations of the movement of the fluid at applied field frequencies of the order of 1MHz and higher. The importance of the illumination in generating the fluid flow is described, the flow depending on both the intensity of illumination and the applied electric field. The theory of electrothermally induced fluid flow is briefly described and compared with the experimental observations. Reasonable agreement is found between the experiments and the theory, with the light generating temperature gradients, and therefore gradients in fluid permittivity and conductivity, and the electric field responsible for the motive force.
Role of Cdk4 in lymphocyte function and allergen response

We recently described a new adhesion pathway in lymphocytes that is dependent on Cyclin-dependent kinase (Cdk) 4 activity and mediates lymphocyte interactions with endothelial matrix. We showed that Cdk4-/- mice had impaired recruitment of lymphocytes following bleomycin model of acute lung injury. In this study, we characterized the development and function of hematopoietic cells in Cdk4-/- mice and assessed the response of Cdk4-/- mice to allergen challenge. Cdk4-/- mice had hypoplastic thymuses with decreased total thymocyte cell numbers and increased CD4/CD8 double negative cells. Cdk4-/- bone marrow (BM) chimeric mice showed similar findings. Thymocytes from either Cdk4-/- or Cdk4-/- BM chimeric mice proliferated equally well as wild type controls in response to IL-2 activation. However Cdk4-/- thymocytes had decreased adhesion to both endothelial cell matrix and fibronectin compared to wildtype (WT) controls, whereas Cdk4-/- and WT splenocytes had similar adhesion. When Cdk4-/- BM chimeric mice and wild type BM chimeric mice were sensitized and challenged by intranasal administration of ovalbumin, we found no differences in allergic responses in the lung and airways between the two groups, as measured by inflammatory cell infiltrate, airway hyperreactivity, IgE levels and cytokine levels. In summary, we show that Cdk4 plays a previously unrecognized role in thymocyte maturation and adhesion, but is not required for thymocyte proliferation. In addition, Cdk4 is not required for lymphocyte trafficking to the lung following allergen sensitization and challenge.
Thermoelectric properties of nanocomposite thin films prepared with poly(3,4-ethylenedioxythiophene) poly(styrenesulfonate) and graphene.

Carbon nanotubes (CNTs), either single wall carbon nanotubes (SWNTs) or multiwall carbon nanotubes (MWNTs), can improve the thermoelectric properties of poly(3,4-ethylenedioxythiophene) poly(styrenesulfonate) (PEDOT : PSS), but it requires addition of 30-40 wt% CNTs. We report that the figure of merit (ZT) value of PEDOT : PSS thin film for thermoelectric property is increased about 10 times by incorporating 2 wt% of graphene. PEDOT : PSS thin films containing 1, 2, 3 wt% graphene are prepared by solution spin coating method. X-ray photoelectron spectroscopy (XPS) and Raman spectroscopy analyses identified the strong π-π interactions which facilitated the dispersion between graphene and PEDOT : PSS. The uniformly distributed graphene increased the interfacial area by 2-10 times as compared with CNT based on the same weight. The power factor and ZT value of PEDOT : PSS thin film containing 2 wt% graphene was 11.09 μW mK(-2) and 2.1 × 10(-2), respectively. This enhancement arises from the facilitated carrier transfer between PEDOT : PSS and graphene as well as the high electron mobility of graphene (200,000 cm(2) V(-1) s(-1)). Furthermore the porous structure of the thin film decreases the thermal conductivity resulting in a high ZT value, which is higher by 20% than that for a PEDOT : PSS thin film containing 35 wt% SWNTs.
Enhancing Transport of Hydrogenophagaflava ENV735 for Bioaugmentation of Aquifers Contaminated with Methyl tert-Butyl Ether

ABSTRACT The gasoline oxygenate methyl tert-butyl ether (MTBE) has become a widespread contaminant in groundwater throughout the United States. Bioaugmentation of aquifers with MTBE-degrading cultures may be necessary to enhance degradation of the oxygenate in some locations. However, poor cell transport has sometimes limited bioaugmentation efforts in the past. The objective of this study was to evaluate the transport characteristics of Hydrogenophaga flava ENV735, a pure culture capable of growth on MTBE, and to improve movement of the strain through aquifer solids. The wild-type culture moved only a few centimeters in columns of aquifer sediment. An adhesion-deficient variant (H. flava ENV735:24) of the wild-type strain that moved more readily through sediments was obtained by sequential passage of cells through columns of sterile sediment. Hydrophobic and electrostatic interaction chromatography revealed that the wild-type strain is much more hydrophobic than the adhesion-deficient variant. Electrophoretic mobility assays and transmission electron microscopy showed that the wild-type bacterium contains two distinct subpopulations, whereas the adhesion-deficient strain has only a single, homogeneous population. Both the wild-type strain and adhesion-deficient variant degraded MTBE, and both were identified by 16S rRNA analysis as pure cultures of H. flava. The effectiveness of surfactants for enhancing transport of the wild-type strain was also evaluated. Many of the surfactants tested were toxic to ENV735; however, one nonionic surfactant, Tween 20, enhanced cell transport in sand columns. Improving microbial transport may lead to a more effective bioaugmentation strategy for MTBE-contaminated sites where indigenous oxygenate degraders are absent.
Coping with challenges to memory in people with mild to moderate Alzheimer's disease: Observation of behaviour in response to analogues of everyday situations

Objectives: To describe ways of coping in people with mild to moderate AD when faced with situations that are challenging to their memory. Method: Twenty-four participants (12 with mild and 12 with moderate AD) were presented with a set of seven tasks that were analogues of everyday situations that tax memory. The participants’ responses were videotaped and analysed. Results: Participants’ coping responses were grouped into seven categories to best reflect the main strategies. Individuals used a significantly greater frequency of effortful problem solving (self-reliance and reliance on carers) (p < 0.01) than other ways of coping. Positive acknowledgement of memory difficulties was used significantly more than negative acknowledgement and defensive coping (concealment and avoidance) (p < 0.01). Conclusion: This study used novel methodology of observation of behavioural responses in analogues of everyday situations. The predominance of effortful problem-solving emphasizes the role of the person with AD as an active agent in the management of memory loss. An emphasis in previous literature on defensive coping and denial is counter-balanced by the finding that participants commonly coped by acknowledging their memory impairment.
Review and Summary of Research on the Embodied Effects of Expansive (vs. Contractive) Nonverbal Displays

In 2010, we published an article in which two experiments demonstrated that expansive (vs. contractive) nonverbal displays produced subjective feelings of power and increased risk tolerance (Carney, Cuddy, & Yap, 2010). One of these experiments demonstrated that such displays increased subjective feelings of power, risk tolerance, and testosterone, and decreased cortisol. Our two experiments were the eighth and ninth to be reported in the literature on the embodied effects of nonverbal expansiveness—seven experiments on this topic were published prior to 2010. Since our article in 2010, 24 additional experiments on the effects of expansive postures have been published (see Table 1). Embodiment and the long-standing discussion of mind-body connection has its experimental roots in William James’s (1890/1950) theories of emotion and ideomotor action. Since then, many studies have demonstrated the bidirectional link between nonverbal behavior and human thought and feeling (see Laird & Lacasse, 2014). One such study was conducted by Ranehill et al. (2015), who reported a conceptual replication of one of our experiments: They found an effect of expansive posture on subjective feelings of power, but no effect of posture on risk tolerance, testosterone, or cortisol. We offer four comments that we hope elucidate the similarities and differences among the 33 published experiments (harvested from the literature through extensive keyword searches and cross-referencing of published articles) and the newly published research of Ranehill et al. We also highlight the specific differences between our experiment and that of Ranehill et al. Unpublished findings were excluded in Table 1. Ranehill et al.’s commentary, with the review presented here, serves as an excellent springboard for identifying potential moderators of the psychological effects of nonverbally expansive (vs. contractive) posture. Thirty-Three Published Results on Expansive Posture
Energy delivered unconditioned for thermal comfort

Energy delivery to households can count up to 50% of primary energy consumption in the United States. As proactive response to this classical engineering sentiment, much efforts made to address this energy delivery process, however, have one one caveat in common: targeting at conditioning only air, despite it being a proxy of occupant comfort. What if we rethink the process of how we delivery energy to ensure that occupant comfort is achieved rather than specific air condition is provided? The proposed dissertation offers an examination of the premises and feasibility on reconditioning the energy delivery for occupant comfort, potentially validating a fundamental change of how energy should be delivered. Looking at potentially including the thermal comfort as a final goal for energy delivery, it is significant to understand what is the underlying potential and consequences of a different look at the energy delivery chain. To better understand the relationship between the energy delivery chain and the thermal comfort of the occupants, proposed projects asks three questions: how would this affect future energy delivery designs, how can we include occupants back to our control loop and eventually, how would we redesign our current delivery chain with new objective concentrated on occupants. To put this into project-specific context, three major projects with their respective follow-up projects will investigate the three questions with a feasibility study of geothermal energy sourced from existing oil/gas boreholes, radiant temperature sensing and analysis of occupant comfort, and Sankey diagrams for existing exergy delivery system. Proposed dissertation would offer an examination in full spectrum the existing energy delivery system’s potential to be re-conditioned for the comfort of the occupants for a potentially fundamental change in how we understand space conditioning: this might be incredibly significant as we might be able to rearrange the entire energy supply chain with ever-more challenging energy outlooks.
The pig as an animal model for human pathologies: A proteomics perspective

Traditional biomedical models are easy to manage in experimental facilities and allow fast and affordable basic genetic studies related to human disorders, but in some cases they do not always represent the complexity of their physiology. Translational medicine demands selected models depending on the particularities of the human disease to be investigated, reproducing as closely as possible the evolution, clinical symptoms and molecular pathways, cells or tissues involved in the dysfunction. Thus, pig models offer an alternative because of their anatomical and physiological similarities to humans and the availability of genomic, transcriptomic and, progressively more, proteomic tools for analysis of this species. Furthermore, there is a wide range of natural, selected and transgenic porcine breeds. The present review provides a summary of the applications of the pig as a model for metabolic, cardiovascular, infectious diseases, xenotransplantation and neurological disorders and an overview of the possibilities that the diverse proteomic techniques offer to study these pathologies in depth.
Transactions and Proceedings of the American Philological Association

To help in commemorating the 450th anniversary of the Ninety-five Theses, the University of Valparaiso has published, with introduction and commentary, this handsome little edition of Nicolaus Marschalk's Wittenberg Commencement Oration of 1503. Marschalk's connection with Luther, as the writer of the Preface allows, was at best tenuous: the Oration is, however, of some interest as illustrating the part played in the Reformation by the spread of humanistic ideas. It is essentially an exhortation to the study of philosophy and humane letters, liberally embellished with examples and anecdotes from classical sources: heady stuff in its day, no doubt, and highly provocative to the worthy magistri satirized in the Epistulae Obscurorum Virorum. Marschalk's scholarly attainments seem to have been more showy than profound, and it was in the printing-house that his chief services to bonae litterae were performed. The Introduction gives a useful account of his publishing activities, which might have included a reference to E. P. Goldschmidt, The First Cambridge Press in its European Setting (1955), pp. 41-4. A facsimile of the original edition of 1503 is appended.