Miracle-dz/UniFAR-FTUs huggingface dataset:
Idarubicinol myelotoxicity: a comparison of in vitro data with clinical outcome in patients treated with high-dose idarubicin

We evaluated in vitro the toxicity of idarubicin and its active metabolite idarubicinol on haematopoietic progenitors, using human umbilical cord blood and peripheral blood progenitors to obtain dose–response curves. We treated 16 patients with poor prognosis lymphoma in a phase I–II trial of high-dose idarubicin and melphalan and investigated if idarubicinol persisting in patients' plasma at the time of transplantation (day 0), on day +1 and +2 could result in an inhibition of infused progenitors. Colony inhibition was correlated with pharmacokinetic data and with the time of patients' engraftment. Plasma samples obtained before idarubicin treatment demonstrated a colony-stimulating effect, increasing the cloning efficiency by 72%. The inhibitory activity on colony forming unit granulocyte–macrophage (CFU-GM) of patients' plasma collected on the day of transplantation was lower than expected from dose–response curves (21% measured vs 70% expected). The time to patients' WBC and PLT recovery correlated with the amount of CD34+ cells reinfused and, to a lesser extent, with the colony-inhibiting effect of patients' plasma. The correlation between idarubicinol concentration and CFU-GM inhibition was not significant. These data suggest that plasma drug concentration on the day of stem cell reinfusion may overestimate the toxicity of residual anthracyclines to the transplanted cells. © 2000 Cancer Research Campaign
Emotional Intelligence and Personality Traits among University Teachers: Relationship and Gender Differences

The aim of the current study was to examine relationship pattern between personality traits and emotional intelligence (EI), besides exploring the gender differences. Sample of the study was comprised 163 university teachers. Wong and Law Emotional Intelligence Scale (2002) and NEO-Five Factor Inventory (NEO-FFI) developed by Costa & McCrae (1992) were used to measure EI and personality traits accordingly. Correlational analysis showed that EI was positively correlated with extraversion, conscientiousness, openness to experience and agreeableness, and negatively with neuroticism. t-test analysis demonstrated that there were no gender differences in EI, openness to experience and agreeableness, whereas significant gender differences were demonstrated on extraversion, conscientiousness and neuroticism.
A NON-RECURSIVE REGRESSION MODEL FOR COUNTRY RISK RATING

The central objective of this paper is to develop a transparent, consistent, selfcontained, and stable country risk rating system, closely approximating one of the major existing ones (Standard & Poor’s). The proposed model uses economic-financial and political variables, is non-recursive (i.e., it does not rely on the previous year’s ratings) and is constructed using multiple regression. The accuracy of the linear regression’s predictions measured by their correlation coefficient with Standard and Poor’s ratings, evaluated by kfolding cross-validation, is 95.6%. The stability of the constructed non-recursive regression model is shown in three ways: by the correlation of the prediction with those of other agencies (Moody’s and The Institutional Investor), by predicting 1999 ratings using the non-recursive multiple regression model derived from the 1998 dataset applied to the 1999 data, and by successfully predicting the ratings of several previously non-rated countries.
An Examination of Weiner's Attribution Theory of Emotion and Achievement Motivation in a Classroom Context.

Two studies investigated Weiner's theory of attribution and emotion in a classroom context with a school-aged population. Relationships between self-efficacy, attributions, and affect were examined. In the first study, 84 grade three students judged self-eff icacy for solving mathematical subtract ion problems, completed a 25-item mathematical subtraction skill test, rated their level of response to four attributions, and indicated their degree of emotional reactions across four affective dimensions. In the second study, 66 grade eight remedial math students completed the same materials, and rated their degree of emotional reactions across eighteen af fect ive dimensions. Results offered support for some of Weiner's theoretical propositions. Attributions to ability and effort were positively associated with performance outcome, and to positive and self-esteem enhancing affective reactions. Attributions to stable causes were found to be associated with emotions related to positive expectancies. Attributions to low ability and low effort displayed negative associations to negative affect, decreased expectancy of success, and displayed a positive relationship to test scores. A number of predictions remained unsupported and several findings in opposition to current attribut ional theory emerged. There was no evidence supporting a low ability or low effort linkage to the emotions of shame or guilt. In general, the concept of at tr ibut ion-independent emot ions was unsupported . Finally, relationships between self-efficacy, affect, and attributions were investigated. Implications of these findings are discussed, and developmental differences noted. Recommendations for future research are presented.
Integrating Simplication Techniques in SAT Algorithms

Propositional Satisfiability (SAT) is fundamental in solving many application problems in Artificial Intelligence and in other fields of Computer Science and Engineering. In the past, it has already been shown that large simplifications can be obtained using algebraic simplification techniques. On the other hand, intelligent backtrack search algorithms for SAT have empirically been shown to be highly effective in pruning the amount of search, applying strategies for non-chronological backtracking and procedures for clause recording. In this paper we propose integrating some algebraic simplification techniques — namely twovariable equivalence and clause inference — within intelligent backtrack search algorithms. When integrated in SAT algorithms, these techniques target the simplification of a problem instance, reducing the associated search cost. With the obtained experimental results we show the importance of the proposed techniques, demonstrating that they are indeed applied in hard real-world problem instances.
Aerobic Conditioning Might Protect Against Liver and Muscle Injury Caused by Short-Term Military Training

Abstract Koury, JC, Daleprane, JB, Pitaluga-Filho, MV, de Oliveira, CF, Gonçalves, MC, and Passos, MCF. Aerobic conditioning might protect against liver and muscle injury caused by short-term military training. J Strength Cond Res 30(2): 454–460, 2016—This study aimed to compare the biochemical markers of muscle and liver injury and total antioxidant capacity in army cadets after a traditional army physical training program and to correlate these effects with aerobic conditioning. Male army cadets (n = 87; age, 20 ± 2 years) were evaluated 12 hours before the start of training (T0), 12 hours after a 30-km march (T1), and 48 hours after military training (T2). Creatine kinase (CK), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) serum levels were measured using an autoanalyzer. Total antioxidant capacity was determined by 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity (Sc%). Seventy-four percent of army cadets were classified as having excellent aerobic conditioning (53.9 ± 3.0 ml·kg−1·min−1 predicted V[Combining Dot Above]O2max from the Cooper test). The median serum concentration of all enzymes increased 12 hours after marching (T1: CK 675%; ALT 59%; AST 336%; AST/ALT ratio 85%; p = 0.001) and 48 hours after the end of training (T2: CK 878%; ALT 256%; AST 418%; AST/ALT ratio 180%; p = 0.001). Sc% was higher in T2 (31.1 ± 9.8%; p = 0.01) than in T0 (3.4% change). Maximal oxygen consumption (ml·kg−1·min−1) correlated negatively with CK (r = −0.25; p = 0.009) and ALT (r = −0.21; p = 0.03) serum levels, and positively with the change in Sc% (r = 0.22; p = 0.04) at T2. The results indicate that intense military training can cause liver and muscle injury and that aerobic conditioning can be considered as a protective factor for these injuries.
A Cloud Gaming System Based on NVIDIA GRID GPU

Like Internet sweeping the world 20 years ago, cloud gaming, today, is gaining in popularity with unimaginable speed. However, many technical issues must be solved through its exploring process. Among all of these problems, bandwidth limitation and support for multi-client concurrent access become the bottleneck for further development of cloud gaming. Cloud gaming is based on real-time audio and video stream, therefore, it will be a great contribution to cloud gaming on research how to encode the stream with minimum time and maximum compression radio. So we are committed to improve the ways of encoding and multi-client concurrent access in the server of cloud gaming. In order to reduce the delay in limited bandwidth and improve multi-client concurrent access efficiency, a concurrent server is built up based on the integration of NVIDIA GRID GPU and the open source cloud gaming platform Gaming Anywhere. As the results show, the latency is reduced and the concurrency is improved in this system.
Incomes of seniors

Adapted from The Maturation of Canada™s RetirementIncome System: Income Levels, Income Inequalityand Low-Income among the Elderly, publishedby Statistics Canada (Catalogue no. 11F0019MPE, no. 147)and by the Canadian Journal on Aging (19, no.3:287-316). John Myles is Professor of Sociology, Florida StateUniversity, and was Visiting Research Fellow with StatisticsCanada™s Business and Labour Market Analysis Division in1998-99. He can be reached at jmyles@garnet.acns. fsu.edu.
On power spectrum optimization by iterative function evaluation

The problem of optimally adjusting the power spectral density level, referred as power spectrum optimization, is a well-known and difficult nonconvex optimization problem. This paper investigates a class of local optimization methods based on a technique called iterative function evaluation. This idea, first proposed in our previous work, is based on the manipulation of the first order condition of the optimization problem into an algorithm. This paper shows that these manipulations are not unique, and proposes a new iterative-function-evaluation-based method for power spectrum optimization. In addition, this paper proposes methods based on the average channel gains for an orthogonal frequency division multiple access network. Finally, the performance of the proposed methods is evaluated in a wireless backhaul application.
Evidence of an in vitro Coupled Diffusion Mechanism of Lesion Formation within Microcosm Dental Plaque

The purpose of this study was to determine whether or not the dual constant-depth film fermenter (dCDFF) is able to produce caries-like enamel lesions and to ascertain further information regarding the performance of this fully functional biological caries model. Conditions were defined by the continuation (CF) or cessation (FF) of a saliva-type growth medium supply during 50-mM sucrose exposures (8 times daily). Hydroxyapatite (n = 3) and bovine enamel (n = 3) substrata were included within each condition and samples extracted after 2, 4, 8, and 16 days. Community profiles were generated for fastidious anaerobes, Lactobacillus spp. , Streptococcus spp. , mutans streptococci (MS), and Veillonella spp. using selective culture techniques and enamel demineralisation assessed by transverse microradiography. Results demonstrated that the dCDFF model is able to produce caries-like enamel lesions with a high degree of sensitivity where reduced ionic strength within the FF condition increased surface layer mineral deposition. Between conditions, biofilm communities did not differ significantly, although MS in the biofilms extracted from the FF condition rose to a higher proportion (by 1.5 log10 units), and Veillonella spp. were initially greater within the CF condition (by 2.5 log10 units), indicating an enhanced ability for the clearance of low-pKa acids following exposures to sucrose. However, both conditions retained the ability for caries-like lesion formation.
The Longue Durée of Literary Prestige

A history of literary prestige needs to study both works that achieved distinction and the mass of volumes from which they were distinguished. To understand how those patterns of preference changed across a century, we gathered two samples of English-language poetry from the period 1820–1919: one drawn from volumes reviewed in prominent periodicals and one selected at random from a large digital library (in which the majority of authors are relatively obscure). The stylistic differences associated with literary prominence turn out to be quite stable: a statistical model trained to distinguish reviewed from random volumes in any quarter of this century can make predictions almost as accurate about the rest of the period. The “poetic revolutions” described by many histories are not visible in this model; instead, there is a steady tendency for new volumes of poetry to change by slightly exaggerating certain features that defined prestige in the recent past.
Erfassung und Struktur des phonologischen und visuell-räumlichen Arbeitsgedächtnisses bei 4-jährigen Kindern

Zusammenfassung. Vor dem Hintergrund der Tatsache, dass Kompetenzen des Arbeitsgedachtnisses eine wesentliche Rolle in vielen Bereichen der kognitiven Entwicklung spielen und insbesondere fur schulleistungsrelevante Fahigkeiten (Lesen, Mathematik, Fremdspracherwerb) eine bedeutsame Vorhersagekraft haben, wurden gangige Aufgaben zur Untersuchung des phonologischen und visuell-raumlichen Arbeitsgedachtnisses an die spezifischen Erfordernisse von 4-jahrigen Kindern angepasst und evaluiert. Diese Aufgaben sollen schon bei jungen Kindern Arbeitsgedachtniskapazitaten erfassen, um eine moglichst fruhe Identifikation von Risikofaktoren fur die weitere kognitive Entwicklung zu ermoglichen. Die Ergebnisse zeigen, dass die Messung subsystemspezifischer Arbeitsgedachtniskapazitaten bei 4-Jahrigen moglich ist. Daruber hinaus interessierte die Binnenstruktur der theoretisch angenommenen Subkomponenten des Arbeitsgedachtnisses. Die Ergebnisse der korrelativen und konfirmatorischen Analysen legen bereits bei 4-Jahrigen e.
Improved Automatic Speech Recognition Using Subband Temporal Envelope Features and Time-Delay Neural Network Denoising Autoencoder

This paper investigates the use of perceptually-motivated subband temporal envelope (STE) features and time-delay neural network (TDNN) denoising autoencoder (DAE) to improve deep neural network (DNN)-based automatic speech recognition (ASR). STEs are estimated by full-wave rectification and low-pass filtering of band-passed speech using a Gammatone filter-bank. TDNNs are used either as DAE or acoustic models. ASR experiments are performed on Aurora-4 corpus. STE features provide 2.2% and 3.7% relative word error rate (WER) reduction compared to conventional log-mel filter-bank (FBANK) features when used in ASR systems using DNN and TDNN as acoustic models, respectively. Features enhanced by TDNN DAE are better recognized with ASR system using DNN acoustic models than using TDNN acoustic models. Improved ASR performance is obtained when features enhanced by TDNN DAE are used in ASR system using DNN acoustic models. In this scenario, using STE features provides 9.8% relative WER reduction compared to when using FBANK features.
Convergent Decomposition Techniques for Training RBF Neural Networks

In this article we define globally convergent decomposition algorithms for supervised training of generalized radial basis function neural networks. First, we consider training algorithms based on the two-block decomposition of the network parameters into the vector of weights and the vector of centers. Then we define a decomposition algorithm in which the selection of the center locations is split into sequential minimizations with respect to each center, and we give a suitable criterion for choosing the centers that must be updated at each step. We prove the global convergence of the proposed algorithms and report the computational results obtained for a set of test problems.
From genes to genome biology: a new era inHelicobacter pylori research

In August 1997 the complete annotated genome sequence of Helicobacter pylori was published,1 just 15 years after the organism was first cultured.2 This is an important milestone in gastroenterology research as H pylori is the first enteropathogen to be fully sequenced. The availability of a complete genetic data set heralds a new era in H pylori research as it will provide a framework for global studies of virulence and other aspects of the organism’s biology. In this article we outline the genomics approaches that can now be applied and highlight the potential practical benefits of this research in terms of eradication therapy and disease prevention. Scientists at The Institute for Genomic Research (TIGR) (http://www.tigr.org) have determined the order of the 1 667 867 nucleotides that constitute the circular chromosomal content of H pylori strain ACTC 26695.1 Initial computer analysis suggests the presence of 1590 open reading frames (ORFs or genes), of which nearly 70% can be matched to genes encoding proteins of known function. This immense achievement gives us unequalled opportunities to relate gene sequence to biology and will provide insight into many aspects of the organism’s biology, such as replication, DNA repair, metabolism, ion and protein transport, cell wall structure, and virulence. The most intriguing findings are as follows:
Mindfulness as a Tool for Managing Visitors to Tourism Destinations

The primary objective of this study was to develop a further understanding of the construct of mindfulness and its application in managing visitors to natural, cultural, or historically based tourism destinations. Mindfulness represents a state of mind expressed by actively processing available information (e.g., brochures) within the surrounding environment, while mindlessness is considered a type of disengagement from information in one’s surroundings. A 7-item Likert-type-scaled mindfulness measure was modified and administered to visitors at four southeastern coastal parks in April/May 1998. Three groups, “not very mindful, ” “mindful,” and “very mindful,” were identified. Significant differences (p < .05) were found among the three groups concerning benefits sought, preference for services, and participation in nature-oriented activities, with the very mindful group standing apart from the other two. Application of mindfulness principles may provide a framework for tourism destinations in meeting visitor needs while also aiding resource management efforts.
PHYSICAL ACTIVITY, NUTRITIONAL STATUS AND ABDOMINAL OBESITY AMONGST PHYSICAL EDUCATION TEACHERS ACTIVIDAD FÍSICA, ESTADO NUTRICIONAL Y OBESIDAD ABDOMINAL EN PROFESORES DEL ÁREA DE LA CULTURA FÍSICA

The purpose of this study was to estimate the prevalence of the level of physical activity, nutritional status and abdominal obesity among Physical Education teachers in Mexicali Baja California. 79 teachers from 43.4 ± 9.8 years of age were studied, in order to classify the level of physical activity the International Physical Activity Questionnaire (IPAQ) was administered, to determine the body mass index and abdominal obesity, anthropometric measurements were taken (weight, height and waist circumference).
Institutional Reform and the Reorganization of Family Support Services

Accounts of institutional change developed from structuration theory (Barley and Tolbert, 1997; Greenwood et al., 2002) are compared with an account developed from Foucauldian theory (Hasselbladh and Kallinikos, 2000). They are considered in the context of a project that was intended to pioneer a new, integrated approach to child and family support services in a deprived area in the North of England. It was undertaken at a time when the British government was pursuing an ambitious programme of reform across the public sector. The project challenged entrenched practices in the statutory agencies (social services, health, education and the police) and also those within independent, voluntary organizations providing services to children and families in the area. None of the theories of institutional change considered here anticipated the muddles, misunderstandings, false starts and loose ends that were a feature of the case. While both structuration theory and Foucauldian theory stress the significance of the internalization of new ideas, problems in this case developed because of the difficulties participants had in externalizing new approaches into new practices. This overlooked aspect of institutional change is conceptualized as a ‘contested ascent’ from the abstract to the concrete.
Spatial-Temporal Tag Mining for Automatic Geospatial Video Annotation

Videos are increasingly geotagged and used in practical and powerful GIS applications. However, video search and management operations are typically supported by manual textual annotations, which are subjective and laborious. Therefore, research has been conducted to automate or semi-automate this process. Since a diverse vocabulary for video annotations is of paramount importance towards good search results, this article proposes to leverage crowdsourced data from social multimedia applications that host tags of diverse semantics to build a spatio-temporal tag repository, consequently acting as input to our auto-annotation approach. In particular, to build the tag store, we retrieve the necessary data from several social multimedia applications, mine both the spatial and temporal features of the tags, and then refine and index them accordingly. To better integrate the tag repository, we extend our previous approach by leveraging the temporal characteristics of videos as well. Moreover, we set up additional ranking criteria on the basis of tag similarity, popularity and location bias. Experimental results demonstrate that, by making use of such a tag repository, the generated tags have a wide range of semantics, and the resulting rankings are more consistent with human perception.
Semantic Role Based Tamil Sentence Generator

A Machine learning technique called memory based bigram models are developed for a system that generate a simple sentence for Tamil language from a set of concept terms and their semantic role. This system consists of a learner to learn how to realize a sentence from the content of semantic role information. This learner has been designed as a statistical model that is formulated from a preprocessed corpus of sentences. This preprocessing work is handled by annotating the corpus using part of speech tagging, chunking and semantic role labeling processes. This collective annotated corpus is statistically analyzed and developed the memory based bigram models. These models thus obtained are capable of producing the appropriate sequence of semantic roles of the concept terms for realizing sentence. A phrase generator has been developed to generate the appropriate phrases involved in sentence generation.