Miracle-dz/UniFAR-FTUs huggingface dataset:
Prevalence, Genetic Characteristics, and Zoonotic Potential of Cryptosporidium Species Causing Infections in Farm Rabbits in China

ABSTRACT To assess the prevalence and public health significance of rabbit cryptosporidiosis, a total of 1,081 fecal specimens were collected between October 2007 and April 2008 from rabbits on eight farms in five different areas in Henan Province, China, and were examined by microscopy after Sheather's sucrose flotation and modified acid-fast staining. The average infection rate of Cryptosporidium was 3.4% (37/1,081 samples). There was a significant association between the prevalence of Cryptosporidium and the age of animals (χ2 = 57.13; P < 0.01); the prevalence of cryptosporidiosis in 1- to 3-month-old rabbits was the highest (10.9%). The Cryptosporidium species in microscopy-positive specimens were genotyped by sequence analyses of the 18S rRNA, 70-kDa heat shock protein (HSP70), oocyst wall protein (COWP), and actin genes and were subtyped by sequence analysis of the 60-kDa glycoprotein (gp60) gene. Only the Cryptosporidium rabbit genotype was identified, with 100% sequence identity to published sequences of the 18S rRNA, HSP70, COWP, and actin genes, and the strains belonged to three gp60 subtypes (VbA36, VbA35, and VbA29). In view of the recent finding of the Cryptosporidium rabbit genotype in human outbreak and sporadic cases, the role of rabbits in the transmission of human cryptosporidiosis should be reassessed.
The novel, actin‐like protein Tact3 is expressed in rodent testicular haploid germ cells

Mouse testis actin‐like proteins 1 and 2 (mTact1 and mTact2), which are expressed in murine haploid germ cells, have been described previously. Here, we report the cloning and characterization of a third actin‐like protein from rat, rat testis actin‐like protein 3 (rTact3). The complete cDNA of the rTact3 gene was approximately 3.7 kb in length, and its corresponding amino acid sequence consisted of 1219 amino acids. The rTact3 gene lacks introns, similar to mTact1 and mTact2. The 356 C‐terminal amino acids of rTact3 showed 43% homology with mTact1, whereas the 863 N‐terminal amino acids did not show any significant homology. Northern blot analysis revealed that rTact3 mRNA was expressed only in adult rat testes and not during the prepubescent stage. In situ hybridization revealed that rTact3 was expressed exclusively during round and elongated spermatids maturation stages in rat testes. Immunohistochemical experiments using antibodies raised against a synthetic peptide showed that the expression of the rTact3 protein was also restricted in round and elongated spermatids, specifically in the head and acrosome of mature rat sperm. The 5′‐flanking region of the mTact3 gene was found to contain a TATA‐box motif as well as two putative CREB/c‐Jun and five C/EBP motifs. mTact3 promoter activity was enhanced in a dose‐dependent manner by the transfection of CREB, c‐Jun, or C/EBP in NIH3T3 cells. These results suggest that Tact3 proteins might play an important role in rodent germ‐cell development. Mol. Reprod. Dev. 80: 988–999, 2013. © 2013 Wiley Periodicals, Inc.
Bone Marrow Findings in Multicentric Castleman Disease in HIV-negative Patients

Because bone marrow histology in multicentric Castleman disease in human immunodeficiency virus-negative patients is not well reported, we investigated sequential bone marrow biopsies of 3 affected human immunodeficiency virus-negative patients, of which one was human herpes virus 8 (HHV8)-positive. The histologic evaluation of the bone marrow revealed lymphoid follicles with regressed germinal centers in 1 patient. Another patient showed tumorlike but bland polyclonal plasmacytosis with large perivascular plasma cell clusters. The HHV8-positive patient revealed interstitial HHV8-positive cells accompanied by a mild plasmacytosis. The atypical lymphoid follicles could be regarded as a bone marrow manifestation of multicentric Castleman disease, whereas the plasmacytosis most likely is the result of excess interleukin 6 production. The presence of HHV8-positive cells within the bone marrow may indicate the dissemination of the virus in a compromised immune system.
[Value of preservation of uvula in uvulopalatopharyngoplasty].

OBJECTIVE To explore the effect of the modified Uvulopalatopharyngoplasty (UPPP) where uvula is preserved in the operation, and whether the postoperative complications are diminished. METHODS Thirty consecutive patients with the obstructive sleep apnea syndrome (29 men, 1 woman) were analyzed by questionnaire, polysomnography and oral cavity measurement before and 6 months after uvulopalatopharyngoplasty to assess the surgical outcome and value of preservation of uvula in the operation. RESULTS Eighty-seven percent of patients reported improvement of snoring and daytime sleepiness. Fifty-three percent of patients showed a decrease of at least 50% in the apnea and hypopnea indices. Among the mild and moderate obstructive sleep apnea (AHI < 50), 73.3% of them showed a decrease of at least 50% in the AHI. No velopalatal insufficiency occurred. The result of oral cavity measurement showed that the uvula, which was preserved completely during the operation, began to contract 2 weeks after the operation. Three to six month after operation, uvula contracted to the normal length and the anatomical shape of the pharyngeal cavity became normal. CONCLUSIONS The results of the uvula preserving UPPP indicate that this approach not only improves the effect of the UPPP, but also avoids the postoperative complications. The uvula that preserved completely during the operation will contract to the normal length progressively.
Towards using administrative databases to measure population-based indicators of quality of end-of-life care: testing the methodology

This study is concerned with methods to measure population-based indicators of quality end-of-life care. Using a retrospective cohort approach, we assessed the feasibility, validity and reliability of using administrative databases to measure quality indicators of end-of-life care in two Canadian provinces. The study sample consisted of all females who died of breast cancer between 1 January 1998 and 31 December 2002, in Nova Scotia or Ontario, Canada. From an initial list of 19 quality indicators selected from the literature, seven were determined to be fully measurable in both provinces. An additional seven indicators in one province and three in the other province were partially measurable. Tests comparing administrative and chart data show a high level of agreement with inter-rater reliability, confirming consistency in the chart abstraction process. Using administrative data is an efficient, population-based method to monitor quality of care which can compliment other methods, such as qualitative and purposefully collected clinical data.
CatCharger: Deploying wireless charging lanes in a metropolitan road network through categorization and clustering of vehicle traffic

The future generation of transportation system will be featured by electrified public transportation. To fulfill metropolitan transit demands, electric vehicles (EVs) must be continuously operable without recharging downtime. Wireless Power Transfer (WPT) techniques for in-motion EV charging is a solution. It however brings up a challenge: how to deploy charging lanes in a metropolitan road network to minimize the deployment cost while enabling EVs' continuous operability. In this paper, we propose CatCharger, which is the first work that handles this challenge. From a metropolitan-scale dataset collected from multiple sources of vehicles, we observe the diversity of vehicle passing speed and daily visit frequency (called traffic attributes) at intersections (i.e., landmarks), which are important factors for charging lane deployment. To select landmarks for deployment, we first group landmarks with similar traffic attribute values using the entropy minimization clustering method, and choose better candidate landmarks from each group suitable for deployment. To determine the deployment locations from the candidate landmarks, we infer the expected vehicle residual energy at each landmark using a Kernel Density Estimator fed by the vehicles' mobility, and formulate and solve an optimization problem to minimize the total deployment cost while ensuring a certain level of expected residual energy of EVs at each landmark. Our trace-driven experiments demonstrate the superior performance of CatCharger over other methods.
An Anthropolinguistic Study on Local Wisdom Embodied in Lexicons of Community System in Kampung Adat Urug

The paper reports a study on local wisdom embodied in lexicons of community system in Kampung Adat Urug. The location of Kampung Adat Urug is in Bogor region, West Java. This study used anthropolinguistic approach by focusing on communication using ethnography model. The results showed that lexicons of community system in Kampung Adat Urug can be categorized into five groups, namely community organization system, community event, place of community event, community system, and community rules. In relation to the function, the lexicons reflect seven functions, namely individual, social, knowledge, economic, reliance, social stratification, and leadership (surveillance). As it talks about local wisdom, the lexicons displays the values of welfare, discipline, health, mutual cooperation, cultural preservation and creativity, environmental concern, commitment, and positive thinking (gratefulness). The present study evinces the noteworthy of preserving the lexicons. It is a counteraction to language attitude performed by the people of Kampung Adat Urug. As in the context of community system, they start to use modern lexicons. The respective situation will indirectly intimidate the existence of local lexicons and local wisdom successively.
ISCASIR at TREC 2015 Temporal Summarization Track

The goal of Temporal Summarization task is to develop systems which can detect useful, new, and timely sentence-length updates about a developing event. This paper describes our participation in Temporal Summarization track of TREC2015. Based on the word embedding technique, we submitted two runs for the summarization task. The query expanding technique is used for the first run and relevant sentences are retrieved by computing the distance between the expanded query and the sentence. The processing of second run is the same with the first run except for the query expanding stage. Using the KBA Stream Corpus 2014, the experimental results show the effectiveness of our approach
The Personality Profiles of Early Adopters of Energy-Efficient Technology

This study investigates whether energy efficiency investments are driven by differences in personality traits among homeowners. Using data on nearly 3,000 households in Germany, we estimate that compared to the median level, homeowners in the lowest quartile of Openness to Experience have 5.0%-23.4% lower propensity to invest in capital-intensive energy efficiency measures, while homeowners in the highest quartile of Agreeableness are 7.7%-18.0% less likelyto do so. Splitting the energy efficiency investments into two groups yields stronger effects of the same two personality traits for window modernisations and thermal insulation installations, whereas no impact of the personality traits is observed for solar energy and other alternative energy systems, possibly because subsidies for the latter were introduced much earlier in Germany, overriding any effects of personality traits in the investment decisions. These findings may also suggest that personality traits are of greater significance for marginal investors.
Does Written Emotional Disclosure about Stress Improve College Students' Academic Performance? Results from Three Randomized, Controlled Studies

Several early studies and subsequent reviews suggested that written emotional disclosure (WED)—writing repeatedly about personal stressful experiences—leads to improved academic performance of college students. A critical review of available studies casts some doubt on this conclusion, so we conducted three randomized, controlled experiments of the effects of WED versus control writing on grade point average (GPA) of college students. In all three studies, WED writing was implemented effectively—it contained more negative emotion language and generated more negative mood than did control writing. In Study 1, WED did not influence GPA during either the writing semester or subsequent semester among 96 students with headaches. In Study 2, WED had no effect on GPA compared with either control writing or no writing conditions among 124 students with unresolved stress. In Study 3, WED did not influence GPA or retention among 68 academically at-risk ethnic minority students, although secondary analyses suggested some benefits of WED among students who wrote more than once, particularly men. These three studies challenge the belief that WED improves academic performance of college students in general. Future research should examine subgroups of students who might benefit from WED.
A novel cis-acting element controlling the rat CYP2D5 gene and requiring cooperativity between C/EBP beta and an Sp1 factor

The rat CYP2D5 gene encodes a cytochrome P450 and is expressed in liver cells. Its expression commences a few days after birth, and maximal mRNA levels are achieved when animals reach puberty. Transfection and DNA binding studies were performed to investigate the mechanism controlling developmentally programmed, liver-specific expression of CYP2D5. Transfection studies using a series of CYP2D5 upstream DNA chloramphenicol acetyltransferase gene fusion constructs identified a segment of DNA between nucleotides -55 and -156 that conferred transcriptional activity in HepG2 cells. Activity was markedly increased by cotransfection with a vector expressing C/EBP beta but was unaffected by vectors producing other liver-enriched transcription factors (C/EBP alpha, HNF-1 alpha, and DBP). DNase I footprinting revealed a region protected by both HepG2 and liver cell nuclear extracts between nucleotides -83 and -112. This region displayed some sequence similarity to the Sp1 consensus sequence and was able to bind the Sp1 protein, as assessed by a gel mobility shift assay. The role of Sp1 in CYP2D5 transcription was confirmed by trans activation of the 2D5-CAT construct in Drosophila melanogaster cells by using an Sp1 expression vector. C/EBP beta alone was unable to directly bind the -83 to -112 region of the promoter but was able to produce a ternary complex when combined with HepG2 nuclear extracts or recombinant human Sp1. C/EBP alpha was unable to substitute for C/EBP beta in forming this ternary complex. A poor C/EBP binding site is present adjacent to the Sp1 site, and mutagenesis of this site abolished formation of the ternary complex with the CYP2D5 regulatory region. These result establish that two transcription factors can work in conjunction, possibly by protein-protein interaction, to activate the CYP2D5 gene.
On the Ethics of Tourism Research

This study focuses on two topics that have heretofore received little attention: ethical standards for publishing tourism research and assessment of the effectiveness of such standards in generating compliance. A random sample of research articles published by 75 tourism journals in 2013 was drawn and 45 were identified that employed the probability sample survey method. Ten rules for ethical reporting of survey results were derived from the World Association for Public Opinion Research Code of Ethics, designed to encourage transparency of method, and applied to the articles. Most articles failed to comply with most of these rules, documenting that the articles did not incorporate the value of research transparency, a foundation of inquiry in social sciences. Recommendations are presented on how to encourage future papers employing this method published in tourism journals to comply with ethical standards for disclosure in order to improve the transparency and credibility of tourism research.
Compact Diplexer With High Isolation Using the Dual-Mode Substrate Integrated Waveguide Resonator

This letter presents a substrate integrated waveguide (SIW) diplexer using the dual-mode resonator. By enhancing the perturbation strength, the resonant frequencies of the dual-mode square cavity can be assigned to required frequencies. Thus, the cavity can be employed as the common resonator to replace the T-junction. The coupling aperture between the common resonator and the triangular resonator is parallel to one resonant mode's magnetic field and perpendicular to the other's. As a result, the isolation between the two channels is increased. Furthermore, the cavities are vertically stacked to realize a compact size. A diplexer with lower and upper channels centered at 8 and 9 GHz, respectively, is designed to verify the proposed concept. The simulated and measured results agree with each other.
Molecular cloning, characterization and expression of immunoglobulin D on pathogen challenge and pathogen associated molecular patterns stimulation in freshwater carp, Catla catla

The primordial immunoglobulin class, IgD, was the first non‐IgM isotype discovered in teleosts. The crucial roles of IgM and IgZ in imparting systemic and mucosal immunity, respectively, in various fish species have been widely established. However, the putative function of a unique IgD isotype during pathogenic invasions has not been well explored. The present study reports the existence of an IgD ortholog in freshwater carp, Catla catla, and further evaluates its differential expression profile in response to bacterial, parasitic and viral antigenic exposure and pathogen associated molecular patterns (PAMPs) stimulation. The IgD of C. catla (CcIgD) cDNA sequence was found to encode 226 amino acids and confirmed homology with heavy chain delta region of Cyprinidae family members. Phylogenetic analysis of CcIgD exhibited greatest similarity with Ctenopharyngodon idella. qRT‐PCR analysis revealed significant upregulation (P < 0.001) of IgD gene expression in kidney with respect to other tissues at 24 hr post‐Aeromonas hydrophila challenge. CcIgD gene expression in skin was enhanced following Streptococcus uberis infection and in blood following Argulus infection and inactivated rhabdoviral antigen stimulation. Further, the treatment of bacterial and viral products (PAMPs) also triggered significant (P < 0.05) increases in CcIgD mRNA expression in kidney. These findings indicate the functional importance of teleost IgD in orchestrating tissue specific neutralization of antigens on stimulation with different pathogens and PAMPs.
The next trans-atlantic frontier: examining the Impact of Language Choice on Support for Transgender Policies in the United Kingdom and the United States

ABSTRACT As American and British gay, lesbian, and bisexual individuals have made major wins for “pinnacle rights,” such as same-sex marriage, attention has increasingly moved to a previously overshadowed part of the lesbian, gay, bisexual, and transgender community: transgender (trans) people. Alongside more visibility in popular culture, trans people have been the subject of policy debates and proposals in both countries, seeking to both restrict and expand their rights. In this article we examine the extent to which language choice affects public support for policies pertaining to trans people in the United States and United Kingdom. We draw upon two survey experiments conducted in the United States and United Kingdom in July 2016 and find that, in general, different ways of referring to the trans population do not affect policy opinions. This study has implications for both understandings of the effectiveness of framing in increasingly media savvy environments and for the future of trans-related policies in the United States and United Kingdom.
Age‐related muscle fatigue after a low‐force fatiguing contraction is explained by central fatigue

The contribution of central fatigue during and after low‐ and high‐force isometric contractions sustained until failure with age is not established. We compared the time to failure and changes in voluntary activation measured using motor point stimulation of 15 young and 15 old adults for an isometric contraction sustained with the elbow flexor muscles at 20% and 80% of maximal voluntary contraction (MVC) force. Young adults had a briefer time to task failure than old adults for the 20% MVC fatiguing contraction, but a similar duration for the 80% task. Voluntary activation was reduced at the end of the 20% MVC task, but by greater magnitudes for old than young adults. The reduction in MVC torque after the low‐force task was associated with the reduction in voluntary activation. After the 80% task, voluntary activation declined to similar levels for the young and old adults. Electromyographic activity levels (% MVC) of the biceps brachii and brachioradialis muscles during the fatiguing contraction were greater for the old than young for the 20% MVC task, but similar with age for the 80% MVC task. Our findings indicate that intensity and duration of contraction can be manipulated in young and old adults to induce varying magnitudes of fatigue within the central nervous system. Aging increases: (1) fatigue within the central nervous system immediately after a low‐force fatiguing contraction, and (2) the potential for large neural adaptations during neuromuscular rehabilitation in old adults. Muscle Nerve, 2008
Effects of Minimum Wages on Employment Dynamics and Prices in the Restaurant Sector: Canada, 1983–2016

Abstract:L'auteure évalue l'incidence du salaire minimum sur la croissance de l'emploi et sur les prix dans le secteur de la restauration, à l'aide de données canadiennes s'échelonnant de 1983 à 2000 et de 2001 à 2016. La spécification utilisée tient compte de l'incidence décalée du salaire minimum ainsi que des variations à plus long terme dans les données. L'auteure constate que le salaire minimum n'a pas d'incidence statistiquement significative sur la croissance de l'emploi entre 1983 et 2000, mais que certains éléments prouvent l'existence de répercussions tardives du salaire minimum sur les prix. Dans le cas des années 2001 à 2016, une incidence négative statistiquement significative est observée sur la croissance de l'emploi, mais les éléments qui permettraient de conclure à l'existence d'une incidence tardive sur les prix à court ternie sont moins nombreux. Les éléments relevés par l'auteure démontrant l'incidence tardive du salaire minimum sur les prix sont toutefois davantage concluants lorsque l'analyse porte sur des périodes d'ajustement plus longues fondées sur une spécification tenant compte des variations à plus long ternie dans les données. Abstract:I estimate the effects of the minimum wage on employment growth and prices in the restaurant industry, using Canadian data from 1983–2000 and 2001–2016. I use a specification that considers lagged effects of the minimum wage as well as longer differences in the data. I find that there is no statistically significant effect on employment growth during 1983–2000, but I find some evidence of pass-through effects of the minimum wage on prices. For 2001–2016, I find a statistically significant and negative effect on employment growth but less evidence of pass-through effects on prices in the short run. However, I find more evidence of pass-through effects on prices when I consider longer adjustment periods based on a specification using longer differences in the data.