Miracle-dz/UniFAR-FTUs huggingface dataset:
Augmentation of oxidant injury to human pulmonary epithelial cells by the Pseudomonas aeruginosa siderophore pyochelin

Pseudomonas aeruginosa causes acute and chronic infections of the human lung, with resultant tissue injury. We have previously shown that iron bound to pyochelin, a siderophore secreted by the organism to acquire iron, is an efficient catalyst for hydroxyl radical (HO.) formation and augments injury to pulmonary artery endothelial cells resulting from their exposure to superoxide (O2.) and/or H2O2. Sources for O2-. and H2O2 included phorbol myristate acetate (PMA)-stimulated neutrophils and pyocyanin. Pyocyanin, another P. aeruginosa secretory product, undergoes cell-mediated redox, thereby forming O2-. and H2O2. In P. aeruginosa lung infections, damage to airway epithelial cells is probably more extensive than that to endothelial cells. Therefore, we examined whether ferripyochelin also augments oxidant-mediated damage to airway epithelial cells. A549 cells, a human type II alveolar epithelial cell line, was exposed to H2O2, PMA-stimulated neutrophils, or pyocyanin, and injury was determined by release of 51Cr from prelabeled cells. Ferripyochelin significantly increased (> 10-fold) oxidant-mediated cell injury regardless of whether H2O2, neutrophils, or pyocyanin was employed. Apo-pyochelin was not effective, and ferripyochelin was not toxic by itself at the concentrations employed. Spin trapping with alpha-(4-pyrridyl-1-oxide)-N-t-butyl-nitrone-ethanol confirmed the generation of HO. , and injury was decreased by a variety of antioxidants, including superoxide dismutase, catalase, and dimethylthiourea. These data are consistent with the hypothesis that the presence of ferripyochelin at sites of P. aeruginosa lung infection could contribute to tissue injury through its ability to promote HO. -mediated damage to airway epithelial cells.
Sleep, fatigue, and depressive symptoms in breast cancer survivors and matched healthy women experiencing hot flashes.

PURPOSES/OBJECTIVES To compare sleep quality and disturbance, fatigue, and depressive symptoms between breast cancer survivors and healthy women experiencing hot flashes and to examine relationships among sleep and remaining variables (fatigue, depressive symptoms, and frequency of hot flashes). DESIGN Cross-sectional, descriptive, comparative pilot study. SETTING University-based outpatient setting. SAMPLE 15 breast cancer survivors and 15 healthy women matched on age, race, and menopausal status. All women had untreated hot flashes (no hormone replacement therapy or other hot flash treatments). METHODS Questionnaires (sleep quality and disturbance, fatigue, and depression); two ambulatory, 24-hour sternal skin conductance monitoring sessions (hot flash frequency); and medical records review. MAIN RESEARCH VARIABLES Sleep quality and disturbance, fatigue, depressive symptoms, and objective hot flash frequency. FINDINGS The majority of participants evidenced poor sleep quality and high sleep disturbance (73% of breast cancer survivors and 67% of healthy women above a cutoff score of 5). Sleep duration was significantly shorter for breast cancer survivors in contrast to healthy women. Nighttime flashes were experienced by 67% of breast cancer survivors and 37% of healthy women. No group differences were found in fatigue, depressive symptoms, or objective hot flash frequency. Global sleep scores were significantly positively correlated with fatigue and depression but not with hot flash frequency. CONCLUSIONS Findings suggest that sleep disturbance is common in menopausal breast cancer survivors and healthy women, is not necessarily related to hot flashes, and may stem from a multifactorial etiology. IMPLICATIONS FOR NURSING Menopausal breast cancer survivors who present with any one of these symptoms should be screened for all symptoms both during and after treatment.
Comparison of transition temperature range and phase transformation behavior of nickel-titanium wires

Objective: The aim of this research was to evaluate the mechanical properties (MP) and degree of the phase transformation (PT) of martensitic (M-NiTi), austenitic (A-NiTi) and thermodynamic nickel-titanium wire (T-NiTi). Methods: The samples consisted of 0.016 × 0.022 inch M-NiTi (Nitinol Classic, NC), A-NiTi (Optimalloy, OPTI) and T-NiTi (Neo-Sentalloy, NEO). Differential scanning calorimetry (DSC), three-point bending test, X-ray diffraction (XRD), and microstructure examination were used. Statistical evaluation was undertaken using ANOVA test. Results: In DSC analysis, OPTI and NEO showed two peaks in the heating curves and one peak in the cooling curves. However, NC revealed one single broad and weak peak in the heating and cooling curves. Austenite finishing (Af) temperatures were 19.7℃ for OPTI, 24.6℃ for NEO and 52.4℃ for NC. In the three-point bending test, residual deflection was observed for NC, OPTI and NEO. The load ranges of NC and OPTI were broader and higher than NEO. XRD and microstructure analyses showed that OPTI and NEO had a mixture of martensite and austenite at temperatures below Martensite finishing (Mf). NEO and OPTI showed improved MP and PT behavior than NC. Conclusions: The mechanical and thermal behaviors of NiTi wire cannot be completely explained by the expected degree of PT because of complicated martensite variants and independent PT induced by heat and stress.
Changes of microvascular perfusion during acute ureteral obstruction in the rat kidney - the influence of gastrin releasing peptide.

INTRODUCTION Peritubular renal microcirculation has not been directly visualized in acute ureteral obstruction. Therefore, we used epiilluminescence intravital microscopy and an animal model for the assessment of microvascular perfusion. MATERIALS AND METHODS In group 1 (n = 5) the left kidney of Wistar rats was exteriorized and placed on a heatable stage for microcirculatory analysis. FITC-dextran was injected for plasma staining. Microcirculatory stability of the model was assessed by a repeated intravital microscopy at baseline, 60, and 120 minutes. In detail, the functional peritubular vessel density (FVD, total vessel length per area in cm/cm(2)), the red blood cell velocities and diameters in/of arterioles and peritubular capillaries and the perfusion index were measured. In group 2 (n = 7) the left ureter was obstructed after baseline microscopy. In a third group (n = 6) the influence of the antidiuretic and vasoconstrictive peptide gastrin releasing peptide on peritubular microcirculation of the obstructed kidney was measured. RESULTS Repeated intravital microscopy did not induce major microcirculatory disturbances in group 1. Acute ureteral obstruction significantly decreased the index of peritubular perfusion. Moreover, FVD was found decreased at 120 minutes after a small rise at 60 minutes. Whereas blood cell velocities were not changed, arteriolar diameters were decreased after 120 minutes. GRP infusion lowered intrapelvic pressures at 60 and at 120 minutes. The transient increase of FVD (group 2) was not observed. The calculated peritubular flow remained nearly constant compared to a decrease in group 2. Histological assessment did not reveal any microscopy induced renal damage nor any differences between the groups. CONCLUSIONS (1) The model is stable for a time period of at least 120 minutes and allows for the direct visualization of the renal peritubular vessels. (2) Peritubular microcirculation shows a significant deterioration during ureteral obstruction. (3) Infusion of GRP may be beneficial for the microcirculation of the acutely obstructed kidney.
Location and Motion Prediction of Consumers in a Large Shopping Mall

It is important to predict consumers' location and motion in a large shopping mall to provide them better service. When a consumer passes regions of a shopping mall, his/her moving trace can be recorded for prediction. Existing approaches cannot be directly used to fulfill such task because handling the ordered region sequences is quite challenging. In this paper, we propose an improved Apriori algorithm called AprioriOS (Apriori for Ordered Sequences) to solve this problem. Using this method, association rules are mined out from ordered region sequences and then used to predict future locations of consumers. We can predict more than one regions that a consumer may pass in future. We also design an association rule querying method and a tree storage structure for location prediction. And we propose a motion prediction method based on 3-axis accelerometer or RFID to predict motions of consumers. Based on the proposed we develop an location and motion prediction system for shopping malls. Our simulation results show that the system is effective in terms of the accuracy of prediction.
On the “third axiom of metric space”

1. In his thesis Frechett defines a metric spacet or class (D) as a class of elements, the relations among which are established by means of a function of pairs of elements of this class. For any two elements x and y of class (D) this function p(x, y) must satisfy three requirements, which we shall call the axioms of metric space. AXIOM I. (Coincidence Axiom.) p(x, y)=0, when and only when x=y. AXIOM II. (Axiom of Symmetry.) p(x, y)=p(y, x). AxIoM III. (Triangle Axiom.) p(x, y)=p(y, z) +p(z, x). It is evident that the metric spaces are cases of the topological spaces of Hausdorff. In addition, Frechet has considered spaces or classes of elements which he calls classes (E). These are classes df elements, the relations among which are established by means of a function 6(x, y) satisfying the coincidence axiom and the axiom of symmetry. A class (E) which is also a topological space of Hausdorff will be called a symmetric space. It is the purpose of the present paper to present a generalization, of the seventh theorem of a joint paper by A. D. Pitcher and E. W. Chittendenil concerning the investigation of Axiom III. These authors considered spaces defined by functions 6(x, y) satisfying Axioms I and II together with one or more of the following three conditions:
Long Chain Polyunsaturated Fatty Acid Synthesis from Deuterated Essential Fatty Acids in Preterm, Term and Intrauterine Growth Retarded Newborn Infants

Indirect evidence has suggested that long chain polyunsaturated fatty acids (LCPUFA) synthesis is insufficient for requirements in the newborn infant, and specially in the premature. We studied in vivo the elongation and desaturation of linoleic acid (LA) to arachidonic acid (ARA) and linoleic (LNA) to docosahexanoic acids (DHA). The infants received 50 mg/Kg of AL and ALN labeled with 5 atoms of deuterium during the first days of life before they were fed. The stable isotopes labeled metabolites (D5) released into plasma were detected in a blood sample taken 24, 48 and 96 hours after enteral dose of essential fatty acids. Lipids were extracted from plasma samples by Blight & Dyer methods and methylated by Morrison. The stable isotopes metabolites was determined with gas chromatography/mass spectrometry in a negative chemical ionization mode.
CO2 Capture by Means of an Enzyme‐Based Reactor

Abstract: We report a means for efficient and selective extraction of carbon dioxide (CO2) at low to medium concentration from mixed gas streams. CO2 capture was accomplished by use of a novel enzyme‐based, facilitated transport contained liquid membrane (EBCLM) reactor. The parametric studies we report explore both structural and operational parameters of this design. The structural parameters include carbonic anhydrase (CA) concentration, buffer concentration and pH, and liquid membrane thickness. The operational parameters are temperature, humidity of the inlet gas stream, and CO2 concentration in the feed stream. The data show that this system effectively captures CO2 over the range 400 ppm to at least 100,000 ppm, at or around ambient temperature and pressure. In a single pass across this homogeneous catalyst design, given a feed of 0.1% CO2, the selectivity of CO2 versus N2 is 1,090 : 1 and CO2 versus O2 is 790 :1. CO2 permeance is 4.71 × 10−8 molm−2 Pa−1 sec−1. The CLM design results in a system that is very stable even in the presence of dry feed and sweep gases.
Organometallic Phosphinimines as Building Blocks for Potential New Radiopharmaceuticals. Synthesis, Structure and Reactivity of Ph3P=NH2+ReO4-

Reactions of the organometallic phosphinimine Ph3P=N-SiMe3 (1), with aqueous ReO4- and 188ReO4- yield the ion pairs Ph3P=NH2+MO4- (M=Re (2); 188Re (4)). The ion pairs undergo dehydration upon heating to produce the neutral Re(VII) species: Ph3P=N-MO3 (M=Re (3); 188Re (5)). The solid state structure of Ph3P=NH2+ReO4- (2) shows the presence of hydrogen bonding between the iminato hydrogen and the rhenium oxo center. The relevance of such reactions for the design of new radiopharmaceuticals is discussed
Japanese encephalitis

Abstract Japanese encephalitis (JE) is an important mosquito-borne infection. As a zoonosis, JE cannot be eradicated, but reduction of the human disease burden can be achieved through routine childhood vaccination in endemic countries, which is a low cost, high benefit measure. This article will review the worldwide epidemiology, vector transmission, genetics and molecular biology of JE, as well as present the pathophysiology, clinical manifestations and complications, diagnosis, treatment and prevention of JE.
Evaluation of cellular behavior in a multilayer structured tubular tissue with the PLCL scaffold

We proposed a 3D assembly technique of small-diameter blood vessels using a PLCL (poly (L-lactide-co-ε-caprolactone)) scaffold. The technique uses a residual stress of PLCL scaffolds to fabricate a multilayer structured tubular tissue, and gives a tissue mechanical property which blood vessels originally have. In the future, we try to test the circulatory culture system in order to investigate whether the tissue-engineered structure maintains the equivalent mechanical property as the human blood vessel. In this work, we demonstrated that fabricated tissues could attach on the inside of tubular PLCL scaffold in the appropriate conditions.
La péninsule Arabique aujourd’hui. Tome I

Voici le second tome de la peninsule Arabique d’aujourd’hui, ouvrage collectif s’adressant au public non specialiste mais desireux de prendre une connaissance attentive de cette region du monde arabe, placee chaque jour au cœur de l’actualite economique, financiere, strategique, diplomatique et religieuse. Le tome I a tente une presentation systematique de la peninsule prise dans son ensemble. Le tome II, Etudes par pays, offre, comme son nom l’indique, vingt-deux etudes sur les divers Etats de la peninsule Arabique. Elles sont regroupees en quatre ensembles : l’Arabie du Sud, le sultanat d’Oman, les Etats du Golfe et l’Arabie Saoudite. La presentation de chaque pays est accompagnee d’une carte et d’une chronologie, pour permettre au lecteur de le situer d’une orientation bibliographique. Nous esperons que ces etudes suggereront la diversite geographique, historique, religieuse, economique et culturelle de cette region, une des plus mal connues du monde arabe.
Loop Closing Detection in SLAM Using Scene Appearance

This thesis is concerned with the detection of loop closing in a Simultaneous Localisation and Mapping (SLAM) application. The loop closing detection problem asks how a robot can ‘recognise’ it has returned to a previously visited location after completing a long circuitous path. Many SLAM implementations look to internal map and pose estimates to make decisions about whether a robot has closed a loop. Approaches that rely on these estimates are generally unreliable in detecting loop closure when true and estimated robot poses diverge greatly. The aim of this thesis is to produce a loop closing detection algorithm that is independent of pose estimates, sensor modality and estimation techniques, and works across a spectrum of workspaces. A key competency required is appearance-based place recognition. In order to achieve this goal, some significant issues pertinent to place recognition, namely perceptual variability and aliasing, have to be resolved. Viewpoint invariant descriptors are derived from observations used to represent local scenes. An efficient retrieval system coupled with indexing techniques allows for rapid comparison between observations based on a similarity function. Similarity relationships between local scenes are then encoded within a similarity matrix. The loop closing problem is then addressed as a sequence detection problem within a similarity matrix. Exploiting the phenomenon that loop closing events occur as off-diagonals within a similarity matrix, a sequence detection algorithm is developed to extract such sequences. Instead of finding matching pair of observations, matching sequences are detected so as to exploit the topological relationships between scenes to reduce false positives. To further tackle the perceptual aliasing problem, spectral decomposition of a similarity matrix is carried out. The effects of repetitive and ambiguous artefacts found within an environment are removed through rank reduction based on an entropy maximisation criterion. Sequence detection is achieved in these rank reduced matrices. A principled manner to determine the probability of sequence occurring randomly allows the evaluation of the significance of such sequences before loop closing is triggered. The practical implementation of the loop closing technique is demonstrated in a variety of challenging scenarios and experimental settings.
The effects of ultrasound-guided corticosteroid injection for the treatment of hemiplegic shoulder pain on depression and anxiety in patients with chronic stroke

ABSTRACT Purpose: We attempted to investigate whether ultrasound (US)-guided intra-articular or subacromial bursa corticosteroid injections can potentially influence the severity of depression and anxiety in patients with chronic stroke with hemiplegic shoulder pain (HSP). Methods: Thirty patients with chronic stroke with HSP received US-guided corticosteroid injections. Numeric rating scale (NRS) scores, passive shoulder range of motion (ROM), Beck Depression Inventory (BDI) scores and Spielberger State-Trait Anxiety Inventory (STAI) scores were evaluated before the injection, and one and two months after the injection. Results: NRS, passive shoulder ROM, BDI and STAI scores were significantly lower one and two months following the injection. Changes in NRS scores were significantly correlated with changes in psychological outcomes (BDI and STAI). Conclusion: US-guided intra-articular or subacromial bursa corticosteroid injections might be a beneficial treatment option for relieving depression and anxiety symptoms in patients with chronic stroke with HSP. Also, US-guided injections appear to be helpful for reducing shoulder pain and increasing shoulder ROM.
Nutrient Metabolism Whole-Body Nitrogen and Splanchnic Amino Acid Metabolism Differ in Rats Fed Mixed Diets Containing Casein or Its Corresponding Amino Acid Mixture 1

Whole-body and splanchnic metabolism of dietary amino acids derived from casein (CAS) or the corresponding crystalline L-amino acid mixture (AA) were compared. Male adult rats were adapted for 9 d to two isoenergetic, isonitrogenous diets (15 g/100 g protein, 5 g/100 g fat) containing either CAS or AA. On d 10, the rats were fed a single mixed meal (3 g dry mass) containing either intrinsically C-labeled goat casein or the amino acid mixture containing [U-C6] leucine and [aN] lysine. Rats were killed before and 1, 3, 5 and 7 h after meal ingestion and samples of plasma, stomach wall and contents, small intestine and liver were collected. C and N enrichments of free and protein-bound amino acids in plasma and tissues were analyzed by gas chromatographycombustion isotope ratio mass spectrometry. Urinary nitrogen excretion was higher (P , 0.05) and weight gain lower (P , 0.05) in rats given the AA diet, indicating a lower whole-body net protein synthesis. Free C-leucine from the AA diet appeared in the intestinal mucosa free pool more rapidly (P , 0.05) than the CAS-C-leucine, probably due to the faster transit through the stomach of the AA group. However, the incorporation of dietary leucine into plasma and liver proteins was higher in the CAS group 7 h after the meal (P , 0.05), whereas lysine incorporation into liver protein was higher in the AA group (P , 0.05). We conclude that whole-body protein homeostasis is better supported by dietary casein-bound than crystalline free amino acids, and that protein-bound leucine, but not lysine, is used more efficiently for liver protein synthesis than dietary free leucine. J. Nutr. 131:
Automatic Choosing of English Rhymes in Translation of Chinese Ancient Poems

Translating Chinese ancient poem is a valuable but hard thing. Automatic choosing of English rhymes in translation of Chinese ancient poems would do translators a favor. This paper extracts three important factors that influence English rhymes, and presents a set of statistical models based on these factors, and then trains these models and acquires their parameters, which at last are used to recommend a list of rhyme for each row of the English version of the poems. Experimental results show that the method is valid and the recommending list is valuable for translators.
A indústria têxtil brasileira em um contexto de transformações mundiais

Este trabalho desvenda um panorama da indústria têxtil mundial e brasileira e suas recentes transformações, tendo como referência as relações de parceria e subcontratação, determinantes de competitividade e da integração entre empresas do setor no plano internacional. Contém uma síntese da visão de complexos e cadeias produtivas e suas manifestação neste setor. Apresenta o “estado da arte” relativo à dinâmica competitiva dessa indústria, tanto em nível nacional como mundial. Evidencia a nova dinâmica de concorrência por meio de novas formas de organização industrial e os principais países envolvidos neste processo. Mostra o desempenho do segmento têxtil no Brasil no contexto de maior concorrência internacional e abertura de mercado. Destaca a dimensão e as transformações recentes ocorridas no segmento têxtil brasileiro, enfatizando sua distribuição geográfica e as relações com o setor externo, o deslocamento de firmas entre regiões e o padrão de comércio internacional com que se defrontam as empresas nacionais. Conclui que após experimentar um declínio nos anos 1990, essa indústria se recupera a partir de 2001, mas sua configuração espacial permanece inalterada, com a região Sudeste ocupando a primeira posição nos setores de fiação, tecelagem e confecção, enquanto a região Sul, no de malhas. Já a indústria da região Nordeste foi a que mais cresceu em todos os segmentos.
CONCEPT DRIFT HANDLING USING REAL TIME STREAM DATA

Stream data are sequence of data examples that continuously arrive at time-varying and possibly unbound streams. These data streams are potentially huge in size and thus it is impossible to process many data mining techniques (e.g., sensor readings, call records, web page visits). Classification techniques fail to successfully process data streams because of two factors: their overwhelming volume and their distinctive feature known as concept drift. Concept drift is defined as changes in the learned structure that occur over time. The occurrence of concept drift leads to a drastic drop in classification accuracy. The recognition of concept drift in data streams has led to sliding-window approaches, instance selection methods, drift detection, ensemble classifiers. This paper describes the various types of concept drifts that affect the data examples and discusses various approaches inorder to handle concept drift scenarios. The aim of this paper is to review and compare single classifier and ensemble approaches to data stream mining respectively and propose a methodology towards its contribution.