Miracle-dz/UniFAR-FTUs huggingface dataset:
Penser la psychanalyse avec Bion, Lacan, Winnicott, Laplanche, Aulagnier, Anzieu, Rosolato [Thinking about psychoanalysis with Bion, Lacan, Winnicott, Laplanche, Aulagnier, Anzieu and Rosolato]1

This book is an introduction to Green’s entire body of works understood in its contemporary, and particularly British, theoretical underpinnings. Prepared by Litza Guttierrez-Green, it brings together publications ranging from 1986 to 2011. The cover shows the detail of a picture by Poliakov that appeared opposite the couch in Green’s office. Fernando Urribarri’s preface gives an overview of the principal stages of Green’s theoretical trajectory. At the end of the book, the bibliography is followed by an index of names and an index of concepts. Green sets out the standpoints of another contemporary analyst he considers important before describing the points of agreement and disagreement and developing his own conception in a way that is supplemented from one chapter to the next. As he writes in relation to Bion, it is a matter of using others’ ideas while remaining faithful to your own thought. They are always evaluated with regard to clinical experience and with reference to Freud’s texts. The critical reading of these authors allows a deeper reinterpretation of Freud and a linkage of knowledge that also respects the contextual differences. This perspective guides him, for example, in according increasing importance to the theory of representation. This forms the basis for comparing the various conceptions. The first chapter, on Bion, the primordial psyche and the work of the negative (originally published in 1998), describes the sources and conditions of thinking. While early Bion (1970) has a scientific quest and becomes disillusioned by it, a later, less easily accessible Bion (1990 [1975–79]) draws on fiction, even science fiction and art, to explore the psyche beyond what is visible and thinkable, the unknowability of the ‘thing in itself’. Seeking the origin of psychic life, he describes the primordial mind, or the ‘beta elements’ of thoughts without a thinker. Sensory experience (therefore external stimuli) and emotional experience (emotion as activation of the drives) and psychic events closely connected with the drive produce these concrete thoughts. Untransformed, they cannot be used and must be evacuated by action or projection into the object (projective identification). However, in his conception of normal projective identification, the object, that is to say the thinker, is able to return an
High-directivity single- and dual-band directional couplers based on substrate integrated coaxial line technology

The high-directivity single- and dual-band directional couplers based on substrate integrated coaxial line (SICL) are first proposed in this paper. As the SICL features the propagation of TEM mode, the SICL directional coupler can keep its high-directivity compared with the microstrip one. The SICL coupler also characterizes a vias-shielded structure keeping it away from lateral leakage, cross-talk or unwanted parallel-plate mode. The design approaches of the single- and dual-band SICL couplers with proper width-spacing are given. Experiments are carried on a SICL 2.35 GHz coupler and a SICL 0.8/2.35 GHz coupler. Compared with microstrip couplers, the SICL ones show a great enhancement in directivity.
A MIXTURE MODEL OF HUBNESS AND PCA FOR DETECTION OF PROJECTED OUTLIERS

With the Advancement of time and technology, Outlier Mining methodologies help to sift through the large amount of interesting data patterns and winnows the malicious data entering in any field of concern. It has become indispensible to build not only a robust and a generalised model for anomaly detection but also to dress the same model with extra features like utmost accuracy and precision. Although the K-means algorithm is one of the most popular, unsupervised, unique and the easiest clustering algorithm, yet it can be used to dovetail PCA with hubness and the robust model formed from Guassian Mixture to build a very generalised and a robust anomaly detection system. A major loophole of the K-means algorithm is its constant attempt to find the local minima and result in a cluster that leads to ambiguity. In this paper, an attempt has done to combine K-means algorithm with PCA technique that results in the formation of more closely centred clusters that work more accurately with K-means algorithm . This combination not only provides the great boost to the detection of outliers but also enhances its accuracy and precision.
Genetic variation and clonal diversity in four clonal sedges (Carex) along the Arctic coast of Eurasia

We studied the structure of genetic variation (at both ramet‐ and genet‐level) and clonal diversity within and among populations in the four closely related arctic clonal sedges Carex bigelowii, C. ensifolia, C. lugens and C. stans by use of allozyme markers. Compared to other sedges and arctic plants, the studied taxa all had high levels of genetic variation, both within populations and taxa. These taxa contained most of the total gene diversity (HT) within populations and a small part of the diversity among populations (GST ranged 0.05–0.43). Carex bigelowii had genetic variation (HS = 0.173, mean for populations) at a comparable level to other outbreeding arctic plants and to other widespread, rhizomatous and mainly outbreeding Carex species. In contrast, C. ensifolia (HS = 0.335), C. lugens (HS = 0.339) and C. stans (HS = 0.294) had within‐population variations that were higher than in most other studied Carex species and for arctic plants in general. Genetic variation was not related to any tested environmental variable, but it was lower in areas deglaciated only 10 000 years bp compared to areas deglaciated 60 000 years bp or not glaciated at all during the Weichselian. All the populations were multiclonal, except for two populations of C. stans that were monoclonal. In contrast to genetic variation, clonal diversity decreased with latitude and did not differ between areas with different times of deglaciation. In accordance with previous studies, C. bigelowii and C. lugens were found to be outbreeding, while C. ensifolia and C. stans had mixed mating systems.
Importance of a proline-rich sequence in the amino-terminal region for correct folding of mitochondrial and soluble microbial p450s.

All microsomal P450s have a proline-rich sequence (PR) in the amino-terminal region that is needed for proper folding [Kusano, K. , Sakaguchi, M. , Kagawa, N. , Waterman, M.R. and Omura, T. (2001) J. Biochem. , 129, 259-269]. There are also multiple proline residues near the amino-termini of the mature forms of all mitochondrial P450s and the amino-termini of soluble microbial P450s. To examine the functional significance of the PR in mitochondrial P450s, we expressed human P450c27 (CYP27) and bovine P450scc (CYP11A1) in an Escherichia coli heterologous expression system, and found that in each one specific proline residue is important for correct folding. Deletions from the amino-terminus further indicated the importance of the PR for the expression of a spectrally normal P450c27. Essentially the same results were obtained with two soluble microbial P450s, P450cam (CYP101) and P450nor, in each of which a PR is important for proper folding. We conclude that in all P450s (mitochondrial, microbial and microsomal P450s), a proline-rich sequence located in the amino-terminal region is important for proper folding. Furthermore, we predict that the importance of the PR in P450 folding is to reduce the tendency of the polypeptide to misfold prior to heme binding.
Preliminary studies of discrete tomography in neutron imaging

Discrete tomography (DT) is a new technique to reconstruct discrete images from their projections (like neutron images). The reconstruction methods in DT are different from the conventional ones, because the created images may contain only a few numbers of given discrete values. One of the main reasons to apply DT is that hopefully we need only a few numbers of projections. In many applications we have a situation where we know the material components of the object to be studied, that is, we know the discrete values of the image to be reconstructed. Using discreteness and some a priori information we can apply several DT methods in neutron imaging. Most of the DT reconstruction methods are reducing the problem to an optimization task. We tried two such methods on software and physical phantoms. In these experiments we investigated the effects of the following parameters: number of projections, noise levels, and complexity of the object to be reconstructed. We also developed a software system, called DIRECT, for testing different DT methods, to compare them and to present the reconstructed objects.
What Is “High Risk?” A Systematic Review of Atopy Risk and Implications for Primary Prevention

Abstract: Atopic diseases are common and becoming more prevalent. Efforts have focused on primary disease prevention by identifying high‐risk children and applying preventative strategies. Our aim was to evaluate methods used to identify high‐risk children in atopy prevention studies. A literature search for relevant articles published between 1986 and 2006 was conducted, and all abstracts were reviewed. The search yielded 1,535 publications, 133 were reviewed in detail, and 57 met inclusion criteria. High risk was defined by 30 different methods. First‐degree relatives with an atopic disorder were included in all methods, but only three publications used referenced questionnaires to determine this. Less frequently included were cord blood immunoglobulin E measurements and skin prick or radioallergosorbent testing, and 16 methods relied on history alone. Family history was the most common method used to predict high risk of atopic disease in a child, but a minority of studies used a tested questionnaire to determine the presence of atopy in family members. The methods used to identify high‐risk children are variable, and the development and widespread use of a validated, practical screening tool is needed.
Calcium metabolism in cancer. Studies using calcium isotopes and immunoassays for parathyroid hormone and calcitonin

Studies of calcium metabolism in 38 patients with cancer indicated that: 1) intestinal absorption of calcium was reduced in patients with skeletal metastases and in those with hypercalcemia; 2) calcium‐47 space (a measurement of bone turnover rate) was high in the patients with skeletal metastases; 3) hypercalcemic patients had higher urinary and endogenous fecal excretion of calcium than those who were normocalcemic; 4) levels of plasma immunoreactive parathyroid hormone were similar in normo‐ and hypercalcemic patients, but the levels for a given serum calcium in malignant disease were lower than those in primary hyperparathyroidism; and 5) some patients had elevated calcitonin levels. Hypercalcemia complicating malignant disease is therefore not due to hyperabsorption or diminished excretion of calcium, and a low calcium diet is unlikely to benefit these patients. Measurement of 47Ca space could be of use in monitoring therapy of patients with skeletal metastases, and measurement of plasma parathyroid hormone could be useful in the differential diagnosis of hypercalcemia.
Demonstration of simultaneous quad-polarization SAR imaging for extended targets in MIMO-SAR

Due to a high demand for global Synthetic Aperture Radar (SAR) data sets, recent spaceborne sensors reach their limits in terms of resolution, swath width and repeat cycle. In addition, fully polarimetric operation reduces the maximum swath width approximately by the factor of two. To solve SAR inherent limitations, a new generation of sensors with multiple transmit and multiple receive channels (MIMO) and digital beam-forming (DBF) capabilities is suggested. Using a quad-polarized MIMO-SAR, transmitting simultaneously orthogonal waveforms in horizontal and vertical polarizations, enables data acquisitions without any reduction of the swath width or resolution. In this paper a concept is described, which uses an advanced filtering and processing method to separate the transmitted signals in the receiver and to measure all four parameters of the scattering matrix simultaneously. Ground-based MIMO-SAR measurement results are presented, which serve as a first verification of the suggested technique with an extended, non point-like target.
A new tool for rapid geriatric assessment in the elderly.

BACKGROUND Geriatric assessment (GA) in the elderly is vitally important for determining the optimal management for patients and the appropriate source of its financing. The search for a novel and compact tool stemmed from the clumsiness and complexity of the traditional instruments in scoring and interpretation. OBJECTIVES To assess the design, application and validity and reliability of a new tool for rapid geriatric assessment in the elderly. METHODS We measured activities of daily living (ADL) scores using the new tool compared with a well-known (Barthel) index in a population study of 90 elderly subjects (20 males and 70 females) in four long-term care departments of a governmental geriatric center, representing a spectrum of subjects (independent, frail, mentally exhausted, and totally dependent). RESULTS There was a good correlation between the two tools, as demonstrated by the correlation curve. The new test was found to be reliable and valid according to the Cronbach and Pearson indexes. Importantly, it took a mean of 5 minutes to complete compared to 20-30 minutes with the traditional tests. The interpretation is simple, unlike the complexity of the other tools. CONCLUSIONS The new tool for rapid geriatric assessment is able to evaluate the same and additional parameters measured by traditional tests and does so in much less time with equivalent validity and reliability.
Olfactory deficits in patients with mild cognitive impairment predict Alzheimer's disease at follow-up.

OBJECTIVE This study evaluated the predictive utility of olfactory identification deficits in patients with mild cognitive impairment for follow-up diagnosis of probable Alzheimer's disease. METHOD Ninety outpatients with mild cognitive impairment were examined at 6-month intervals. Matched healthy comparison subjects (N=45) were examined annually. The University of Pennsylvania Smell Identification Test was given at baseline. RESULTS Olfaction scores were lower in patients with mild cognitive impairment than in healthy comparison subjects. Seventy-seven patients were followed up; 19 were diagnosed with Alzheimer's disease by 2 years. Patients with low olfaction scores (< or =34 of 40), and patients with low olfaction scores who reported no subjective problems smelling, were more likely to develop Alzheimer's disease than other patients. In a Cox proportional hazards model adjusted for age, sex, modified Mini-Mental State score, and education, low olfaction scores did not predict time until development of Alzheimer's disease, but low olfaction scores accompanied by lack of awareness of olfactory deficits predicted time to development of Alzheimer's disease. This effect remained when attention or memory measures replaced modified Mini-Mental State score in the model. In patients with high Mini-Mental State scores (> or =27 of 30), low olfaction with lack of awareness remained a significant predictor of Alzheimer's disease. Olfaction scores of 30-35 showed moderate to strong sensitivity and specificity for diagnosis of Alzheimer's disease at follow-up. CONCLUSIONS In patients with mild cognitive impairment, olfactory identification deficits, particularly with lack of awareness of olfactory deficits, may have clinical utility as an early diagnostic marker for Alzheimer's disease.
MASALAH SOSIAL DAN WIRAUSAHA SOSIAL

Memahami masalah sosial sangat penting bagi mereka yang bergerak di bidang social entrepreneurs. Dengan memahami keluasan serta kedalaman masalah, maka kita akan terbantumenemukan peluang-peluang untuk aksi penanganan baik yang sifatnya pencegahan, penyelesaian, atau pengembangan. Penyebab masalah sosial sangatlah kompleks merentang dari dimensi yang terkait dengan pola tingkah laku, pola interaksi, perubahan dan konflik nilai, sampai yang diakibatkan oleh situasi ketidakadilan, pengabaian terhadap hak-hak asasi manusia, serta kerusakan ekologis yang parah. Ditengah berbagai masalah sosial yang semakin kompleks baik dari penyebab maupun akibatnya, diharapakan muncul para wirausahawan sosial yang mampu menyumbangkan ide dan aksi untuk masalah-masalah yang selama ini dianggap tidak terpecahkan. Dibutuhkan rumusan-rumusan model kreatif dalam upaya pemecahan masalah sosial yang sebelumnya hanya didekati dengan cara-cara konvensional yang dicirikan dengan penerapan model-model kuratif, orientasi proyek jangka pendek, pengawasan implementsi yang lemah sehingga penuh ketidakkonsistenan antara tatanan ide dengan implementasi, dan tidak mampu memunculkan kesadaran kolektif masyarakat bahwa mereka adalah aktor utama perubahan. Sering pula terjadi pihak-pihak yang memiliki otoritas baru melakukan upaya pencegahan atau penanganan masalah setelah terjadi kerusakan yang signifikan. Bagi para wirausahawan sosial, keadaan seperti demikian sebaiknya dilihat sebagai peluang untuk menciptakan model-model jitu diluar pendekatan biasa yang tidak menyelesaikan masalah atau bahkan hanya seolah-olah menyelesaiikan masalah. Saat ini banyak masalah sosial di Indonesia yang perlu menjadi perhatian baik itu yang bersumber dari disfungsi sosial individu, keluarga, atau disfungsi kelembagaan dan organisasi termasuk lembaga-lembaga pelayanan sosial dan publik.
Application of a novel soft phase-locked loop in directly-driven permanent magnet wind power generation system

In directly-driven permanent magnet synchronous gene-rator (PMSG) system, a fast, robust and precise phase angle detector is most important to calculate feedback variables for control the power factor and the flow of active,reactive power. Because the grid side converter of directly-driven PMSG system is connected to the power network directly, the angle information can be easily corrupted by the distorted utility voltage such as voltage unbalance and harmonics in waveform. In this paper, a new phase locked loop (PLL) method with decoupling network using all pass filter (APF) in a synchronous reference frame to extract the positive sequence components of the grid voltage under unbalance grid condition is proposed. Thus a better stability of directly-driven PMSG system can be achieved. Proposed method does not cause harmonics in the reference signal by adequately eliminating unbalance components and high-order harmonic terms in the utility voltage. The proposed PLL is completely implemented in software without any filters. The effect of PLL applied in PMWG system is verified by simulations and experiments.
Visually stressful striped patterns alter human visual cortical functional connectivity

Visually stressful striped patterns with a spatial frequency (SF) of around 3 cycles per degree (cpd) can induce perceptual illusions/distortions and visual discomfort in most people, headaches in patients with migraine, and seizures in patients with photosensitive epilepsy. Patterns with SF ∼0.3 cpd have no such effects and are not uncomfortable to look at (non‐stressful). The effects of the striped patterns on visual cortical activation have been investigated, but their effects on the visual cortical network remain to be studied. A prolonged visual stimulation with stressful patterns may alter the functional connections within the visual system, and their relationship with other networks. Using resting‐state fMRI, this study revealed that the functional connections within the visual system were significantly enhanced by visually stressful stimulation. The functional connectivity between V1 and other brain regions was also significantly modified. Non‐stressful stimulation produced no such significant effects. More importantly, the effects outlasted the stimulation, and this applied both to those effects within and those beyond the visual cortex, suggesting that repeated prolonged visual stimulation with stressful patterns may alter functional connections of the brain and this might be utilized as a visual neuromodulation approach for treatments of visually triggered headaches in migraine patients and visually induced seizures in patients with photosensitive epilepsy. Hum Brain Mapp 38:5474–5484, 2017. © 2017 Wiley Periodicals, Inc.
‘Intergenic’blr gene in Escherichia coli encodes a 41‐residue membrane protein affecting intrinsic susceptibility to certain inhibitors of peptidoglycan synthesis

In the annotation of genomic sequences, small open reading frames (ORFs) are often neglected, particularly if they have no homology to other ORFs or proteins. A mini‐TnphoA insertion in a 602 bp ‘intergenic’ region of the Escherichia coli chromosome at genomic nucleotide 1702674 gave rise to a membrane‐bound PhoA fusion protein and a two‐ to fourfold increase in the intrinsic susceptibility to a wide spectrum of beta‐lactam antibiotics without affecting beta‐lactamase activity or susceptibility to tetracycline, chloramphenicol, gentamicin or quinolones. Susceptibility was also increased to cycloserine and bacitracin, but not to fosfomycin or valinomycin; these drugs, like beta‐lactams, inhibit peptidoglycan synthesis, although by different mechanisms. A clone bearing only 358 bp of this ‘blr’ region restored resistance to the parental level. Two amber mutations in the clone prevented such restoration and were counteracted by an amber suppressor, proving that the active species is a protein. The Blr protein has 41 amino acids, with a single predicted transmembrane helix, but no clear homology to any other protein. A transcriptional start exists 39 bp upstream from the translational start. The membrane location of Blr suggests that it may be part of an efflux pump or involved in murein metabolism. The results indicate that genes for other very small functional proteins may lie within ‘intergenic’ regions.
Real-time optimal trajectory planning with terrain avoidance using MILP

This paper presents an efficient approach to real-time trajectory planing for an autonomous aerial vehicle with terrain avoidance constraints. The trajectory optimization problem is formulated as receding horizon mixed-integer linear programming (MILP). The paper considers the case that only the terrain environment within the detection radius around the vehicle is known and modeled as a triangulated irregular network (TIN). The terrain avoidance constraint is represented in MILP form by introducing binary variables. The trajectory obtained is optimal in term of fuel, time, altitude, etc. The algorithm is applied to a small-scale helicopter with an example scenario and the simulation result shows it is applicable to online computation for real-time implementation through the use of powerful MILP solver of CPLEX.