Miracle-dz/UniFAR-FTUs huggingface dataset:
Magnetic information storage on polymers by using patterned single-molecule magnets.

Ein molek lbasiertes magnetisches Material mit paramagnetischer Antwort bei Raumtemperatur wurde zur Erzeugung von Mustern aus magnetischen Bits auf einer Polycarbonatoberfl che genutzt. Dieses System eignet sich f r eine effektive permanente Informationsspeicherung mit magnetischem Auslesen. Weitere Einzelheiten finden Sie in der Zuschrift von J. Veciana, F. Biscarini et al. auf den folgenden Seiten.
Does treatment have an impact on incidence and risk factors for autism spectrum disorders in children with infantile spasms?

Infantile spasms (IS) are a severe form of childhood epilepsy associated with autism spectrum disorders (ASD) in up to 35% of cases. The objective of this post hoc analysis of our randomized control trial was to determine whether rapid diagnosis and treatment of IS could limit the incidence of ASD while identifying risk factors related to ASD outcome.
Ultra-Wideband (UWB) Microstrip Bandpass Filters with Improved Upper-Stopband and Miniaturized Size

An ultra-wideband (UWB) microstrip bandpass filter with improved upper-stopband and miniaturized size is presented. A modified multiple-mode resonator is formed by transversely attaching three pairs of non-uniform and folded stubs. Its configuration is then investigated, aiming to allocate the first three resonant frequencies within 3.1-10.6 GHz band while suppressing spurious harmonics at the upper-stopband. Plus, its high-impedance sections in two sides are linked with two feed lines via interdigital coupled lines, leading to make up an initial UWB filter. Then, two-stage UWB bandpass filter is constructed to sharpen the rejection skirt and deepen the upper-stopband. Finally, two filters are optimized, fabricated and measured to give us an evident confirmation on the improved UWB performance.
Cuticular Hydrocarbon Synthesis in Relation to Feeding and Developmental Stage in Nymphs of Blattella germanica (Dictyoptera: Blattellidae)

The patterns of hydrocarbon synthesis and transport to the epicuticle were examined in males and females of the German cockroach, Blattella germanica (L.), during the last nymphal stadium. Methods used to extract hydrocarbon from insects were validated in detail. A double hexane extraction for cuticular hydrocarbons and a triple chloroform-metha-nol extraction of homogenized insects for internal lipids removed essentially all hydrocarbon from the respective compartments, whereas the external extraction did not remove hydrocarbon from the interior of the insect. Synthesis in vivo was measured by the incorporation of [1-14C] propionate into methyl-branched hydrocarbon at 2-d intervals throughout the stadium. In both sexes, hydrocarbons were synthesized at increasing rates during the first 2/3 of the stadium, then synthesis ceased 2 d before the imaginal molt. Hydrocarbon synthesis was related to stage-specific food intake in both male and female nymphs. A declining proportion, but relatively constant quantity, of newly synthesized hydrocarbon was transported to the epicuticle as the nymph progressed through the intermolt period. The majority of the newly synthesized hydrocarbon at all ages was retained internally, however, suggesting that they serve as a source of epicuticular and ovarian hydrocarbon in the adult. Gas-liquid chromatography confirmed the patterns of hydrocarbon synthesis and showed a greater accumulation of hydrocarbons internally than on the nymphal epicuticle. Early in the last stadium, the majority of internal hydrocarbon is in the hemolymph, whereas late in the stadium the fraction of internal hydrocarbon in the hemolymph declines, presumably as newly synthesized hydrocarbon begin to associate with fat body and the developing imaginal cuticle.
A randomized controlled trial of strapping to prevent post-stroke shoulder pain

Objective: To determine whether strapping the shoulder in hemiplegic stroke patients: (1) prevents the development, or reduces the severity, of shoulder pain, (2) preserves range of movement in the shoulder, and (3) improves the functional outcomes for the arm and patient overall. Design: A prospective, randomized, single-blind controlled trial of shoulder strapping versus no strapping. Setting: Care of the elderly wards in a teaching hospital, Christchurch, New Zealand. Subjects: All patients admitted with an acute hemiplegic stroke, who had persisting weakness of shoulder abduction. Intervention: The treatment group had their affected shoulder strapped for six weeks from randomization in addition to standard physiotherapy. Main outcome measures: All subjects were assessed at entry (week 0), at end of the treatment phase (week 6) and two months later (week 14). A visual analogue scale (VAS) was used to assess shoulder pain severity whereas shoulder range of movement to the point of pain (SROMP) assessed passive range of movement and pain. Functional Independence Measure (FIM), Motor Assessment Scale (MAS) and Rankin Disability Index measured functional outcomes. Results: Ninety-eight subjects participated (49 strapped, 49 controls). Intention to treat analysis showed no significant difference in pain, range of movement or functional outcomes after the intervention phase or at the final assessment. However there were trends for less pain at six weeks (VAS, p = 0.11) and better final upper limb function (MAS, p = 0.16) in strapped patients. Skin reactions were uncommon (6.1%). The presence of neglect or sensory loss, but not subluxation, at baseline was independently associated with poor outcome. Range of movement was lost early (mean difference SROMP between hemiplegic and contralateral shoulders at baseline = 15.2° (95% CI 10.9–19.5)) and continued throughout the study. Shoulder strapping did not alter the rate at which range of movement was lost. Conclusions: No significant benefit with shoulder strapping was demonstrated and reasons for this are discussed. Range of movement in the hemiplegic shoulder is lost very early and any preventive treatments need to begin within the first 1–2 days after a stroke.
Five chemically rich species of tropical marine cyanobacteria of the genus Okeania gen. nov. (Oscillatoriales, Cyanoprokaryota)

An adverse consequence of applying morphology‐based taxonomic systems to catalog cyanobacteria, which generally are limited in the number of available morphological characters, is a fundamental underestimation of natural biodiversity. In this study, we further dissect the polyphyletic cyanobacterial genus Lyngbya and delineate the new genus Okeania gen. nov. Okeania is a tropical and subtropical, globally distributed marine group abundant in the shallow‐water benthos. Members of Okeania are of considerable ecological and biomedical importance because specimens within this group biosynthesize biologically active secondary metabolites and are known to form blooms in coastal benthic environments. Herein, we describe five species of the genus Okeania: O. hirsuta (type species of the genus), O. plumata, O. lorea, O. erythroflocculosa, and O. comitata, under the provisions of the International Code of Nomenclature for Algae, Fungi, and Plants. All five Okeania species were morphologically, phylogenetically, and chemically distinct. This investigation provides a classification system that is able to identify Okeania spp. and predict their production of bioactive secondary metabolites.
Evaluation of geometrical arrangements of high resolution sensors in PET probe configuration

The probe arrangement in positron emission tomography (PET) is a combination of a high resolution detector (probe) placed within a whole body PET scanner. An additional subset of high-resolution data is recorded that contains events where one of the annihilation photon pair interacted in the high resolution detector. A study was designed to evaluate impact of probe geometry and efficiency on the quality of obtained image. The performance was predicted by estimating mean and variance of efficient estimators such as MLEM based on imaging matrix evaluated at particular probe geometry. Results were compared to data measured at a high-resolution PET probe prototype constructed at University of Michigan. The prototype consists of two arcs of standard PET detector elements at 50 cm radius combined with silicon sensors segmented into 1 mm3 at 5.7 cm radius. A high-resolution Derenzo phantom filled with 18F-flourodeoxyglucose was rotated during a scan. Limited angle probe geometry was simulated by selection of a subset of phantom angular views. Data reconstruction was matched to algorithms evaluated in theoretical predictions. Two parameters, contrast recovery coefficient (CRC) and signal to noise ratio (SNR) were compared to predicted values. The data shows a 50 % increase in CRC and SNR at an event ratio of 10 % where improvement is maximized for a subset of angular positions. Splitting high-resolution data to two perpendicular angular positions improves CRC and SNR.
Normal Age-Related Sensitivity Loss for a Variety of Visual Functions Throughout the Visual Field

Purpose. The purpose of this study is to compare the rate of age-related decline, the magnitude of practice effects, and test–retest variability among normal subjects using six different tests of visual function. Methods. One hundred normal subjects aged between 20 and 85 were enrolled in the study. Six visual field test procedures were used consisting of standard automated perimetry (SAP), short wavelength automated perimetry (SWAP), temporal modulation perimetry (TMP), frequency-doubling technology perimetry (FDT), detection acuity perimetry (DAP),and resolution acuity perimetry (RAP). To facilitate direct comparison, the results for each test were divided by that test’s estimated dynamic range. Results. Of the three tests used clinically most commonly, SWAP exhibited the greatest aging and practice effects and test–retest variability followed by FDT with SAP exhibiting the least. RAP was the most variable test followed by TMP. Conclusions. These results should be taken into account when evaluating glaucomatous loss using different functional tests and when comparing the performance, predictive power, and speed of detection of the different tests.
Serotonin 5-HT2C Receptor Homodimer Biogenesis in the Endoplasmic Reticulum

Dimerization is a common property of G-protein-coupled receptors (GPCR). While the formation of GPCR dimers/oligomers has been reported to play important roles in regulating receptor expression, ligand binding, and second messenger activation, less is known about how and where GPCR dimerization occurs. The present study was performed to identify the precise cellular compartment in which class A GPCR dimer/oligomer biogenesis occurs. We addressed this issue using confocal microscopy and fluorescence resonance energy transfer (FRET) to monitor GPCR proximity within discrete intracellular compartments of intact living cells. Time-lapse confocal imaging was used to follow CFP- and YFP-tagged serotonin 5-HT2C receptors during biosynthesis in the endoplasmic reticulum (ER), trafficking through the Golgi apparatus and subsequent expression on the plasma membrane. Real-time monitoring of FRET between CFP- and YFP-tagged 5-HT2C receptors was performed by acceptor photobleaching within discrete regions of the ER, Golgi, and plasma membrane. The FRET signal was dependent on the ratio of CFP- to YFP-tagged 5-HT2C receptors expressed in each region and was independent of receptor expression level, as predicted for proteins in a non-random, clustered distribution. FRET efficiencies measured in the ER, Golgi, and plasma membrane were similar. These experiments provide direct evidence for homodimerization/oligomerization of class A GPCR in the ER and Golgi of intact living cells, and suggest that dimer/oligomer formation is a naturally occurring step in 5-HT2C receptor maturation and processing.
Comparison of k-shortest paths and maximum flow routing for network facility restoration

In the development of technologies for span failure restoration, a question arises about the restoration rerouting characteristics to be specified. In theory, maximal rerouting capacity is obtained with a maximum flow (Max Flow) criterion. However, rerouting that realizes the k-successively shortest link disjoint paths (KSP) may be faster, easier, and, in distributed implementation, more robust than a distributed counterpart for Max Flow. The issue is, therefore, what the restoration capacity penalty is if KSP is used instead of Max Flow. To explore this tradeoff, the authors present a comparative study of the effectiveness of KSP versus Max Flow as an alternative rerouting criteria in the context of transport network span restoration. The comparison applies to both centrally controlled and distributed restoration systems. Study methods include exhaustive span failure experiments on a range of network models, and parametric and analytical investigations for insight into the factors resulting in KSP versus Max Flow differences. The main finding is that KSP restoration capacity is more than 99.9% of that from Max Flow in typical network models. The hypothesis is made that a generalized "trap" topology is responsible for all KSP-Max Flow capacity differences. The hypothesis is tested experimentally and used to develop analytical bounds which agree well with observed results. These findings and data are relevant to standards makers and equipment developers in specifying and engineering future restorable networks. >
Studies into Computational Intelligence and Evolutionary Approaches for Model‐Free Identification of Hysteretic Systems

This article introduces a robust hybrid computational method for the data‐driven model‐free identification of nonlinear systems that exhibit hysteretic behavior. The proposed approach combines Genetic Programming, which incorporates discontinuous basis functions, for discovering the structure of the governing differential equations, Genetic Algorithms for optimizing the parameters of the differential equations, and Computer Algebra for simplifying mathematical expressions symbolically, and consequently, controlling bloat through condensing dependent terms. A similar technique has been previously proposed by the authors for the identification of nonhysteretic Single Degree of Freedom (SDOF) systems. That technique is extended in this article and is utilized to provide parsimonious differential equations that represent the Bouc–Wen model and the bilinear hysteretic oscillator—both exhibit abrupt change in their memory‐dependent response. The representative models are subjected to validation excitations that are substantially different from the probing signals to confirm the generalizability of the models for different dynamical phenomena. The results verify the effectiveness of the approach and the accuracy of the subsequent differential operators that characterize the behavior of the studied hysteretic systems even under new dynamical conditions. Beside the presented application of this approach, the introduced methodology is more general and can be employed across different disciplines, specifically in data analytics for mathematical modeling of various complex systems.
Expression of P2X5 in lymphoid malignancies results in LRH‐1‐specific cytotoxic T‐cell‐mediated lysis

Minor histocompatibility antigens (MiHA) selectively expressed by haematopoietic cells are attractive targets for specific immunotherapy after allogeneic stem cell transplantation (SCT). Previously, we described LRH‐1 as a haematopoietic‐lineage restricted MiHA that is capable of eliciting an allogeneic cytotoxic T‐lymphocyte (CTL) response after SCT and donor lymphocyte infusion. Importantly, the gene encoding LRH‐1, P2X5, is not expressed in prominent graft‐versus‐host‐disease target tissues such as skin, liver and gut. Here, we investigate whether LRH‐1‐specific immunotherapy may be exploited for the treatment of lymphoid malignancies. We examined P2X5 mRNA expression in a large panel of patient samples and cell lines from different types of lymphoid malignancies by real‐time quantitative reverse transcription polymerase chain reaction. P2X5 mRNA was highly expressed in malignant cells from all stages of lymphoid development. Furthermore, all LRH‐1‐positive lymphoid tumour cell lines were susceptible to LRH‐1 CTL‐mediated lysis in flow cytometry‐based cytotoxicity assays. However, interferon‐γ production was low or absent after stimulation with some cell lines, possibly due to differences in activation thresholds for CTL effector functions. Importantly, primary cells from patients with lymphoid malignancies were effectively lysed by LRH‐1‐specific CTL. These findings indicate that MiHA LRH‐1 is a potential therapeutic target for cellular immunotherapy of lymphoid malignancies.
Team based learning in computer science students

This research is an experiment on the implementation of Team Based Learning (TBL) in computer science students. 64 participants from Mobile Game Creative Design class was selected, and 3 variables are measured: motivation, engagement, academic achievement. The finding shows that although motivation and engagement are not affected, academic achievement shows a significant improvement with a p-value of 0.0000271. This research serves as one of the basis to be considered when a university intends to implement TBL into its learning process.
A REAL LIFE WEB BASED MARKETING OPTIMIZATION FRAMEWORK with EXTERNAL DATA

Big data and data science studies in recent years are booming exponentially, parallel to the data collected and increased processing speeds. As an inevitable consequence, most of the web-based companies are migrating their business models to novel technologies based on the big data and data science research. This paper is based on a real life experience based on one of the web stores with highest volume sales in Turkey. The project was building a data science model on big data technologies to make estimations based on the external data, such as weather conditions, customer demography, news at newspapers, current product alternatives, financial facts (like currency exchange rate or stock market values) and most importantly the sentimental analysis and opinion mining on social network, blogs and news. In the paper, details of problems and possible solution alternatives and methodology for problem solving and solutions and outcomes of the study are explained in the given order.
Animal Communication and Human Language: An overview

Comparative research has proven to be a fruitful field of study on the ontogenetic and phylogenetic evolution of language, and on the cognitive capacities unique to humans or shared with other animals. The degree of continuity between components of human language and non-human animal communication systems, as well as the existence of a core factor of language, are polemic subjects at present. In this article, we offer an overview of the research on animal communication, comparing the resulting data with the current knowledge on human language development. We try to summarize what is currently known about “language abilities” in multiple animals, and compare those facts to what is known about human language. The aim of the article is to provide an introduction to this particular topic, presenting the different sides of the arguments when possible. A special reference is made to the question of syntactic recursion as the main component of language, allegedly absent among non-human animals. We conclude that the current state of knowledge supports the existence of a certain degree of continuity between different aspects of animal communication and human language, including the syntactic domain.
Symetries dans les reseaux colores : definition, analyse et application a l'evaluation de performance

Dans cette these, nous etendons la definition du graphe symbolique aux reseaux colores generaux, et nous presentons un ensemble de proprietes qui peuvent etre etudiees directement sur ce graphe. Cependant, la construction du graphe symbolique ne peut etre effectuee de maniere automatique s'il n'existe aucune contrainte dans la maniere de decrire un modele. En effet, cette construction repose sur la connaissance d'un ensemble de symetries de comportement pour differents objets composant le systeme etudie. Nous proposons les reseaux colores bien formes, une classe de reseaux colores pour laquelle les symetries sont determinees de maniere systematique, ce qui permet une construction entierement automatique du graphe symbolique. Ceci est d'autant plus interesant que nous prouvons que les reseaux bien formes ont la meme puissance d'expression que les reseaux colores. A partir des reseaux bien formes, nous derivons un modele stochastique qui peut etre analyse efficacement au moyen de l'agregation markovienne. En effet, si la temporisation introduite dans le modele respecte les symetries de comportement qui existent pour le modele qualitatif, les marquages symboliques constituent des classes d'etats au sens markovien. En prouvant que tous les etats d'une classe ont la meme probabilite, nous montrons que cette agregation s'effectue sans perte d'information. Nous illustrons sur des exemples d'architectures multiprocesseurs le gain de complexite enorme obtenu avec cette methode
Meiosis in Aspergillus nidulans: another example for lacking synaptonemal complexes in the absence of crossover interference.

Immature cleistothecia of Aspergillus nidulans (mutant bi, del) were serial-sectioned and studied by electron microscopy. Synaptonemal complexes or other conspicuous signs of chromosomal pairing were not observed in this material. This deviation from most other eukaryotes may be of significance for explaining the likewise unusual absence of crossover interference in this organism, as well as in Schizosaccharomyces pombe. In addition, we report on division spindles and spore formation in A. nidulans.
Prevalence and risk factors for posttraumatic stress disorder: a cross‐sectional study among survivors of the Wenchuan 2008 earthquake in China

Background: The impact of the May 2008 Wenchuan earthquake, measuring a massive 8.0 on the surface wave magnitude scale, on public health in China has been significant and multifaceted. In light of extant data on prevalence and risk factors for posttraumatic stress disorder (PTSD) after other natural diasters, we collected data from the Wenchuan earthquake survivors to estimate the prevalence of PTSD and to characterize a range of PTSD risk factors. Methods: A cross‐sectional multicluster sample survey of 446 respondents (201 from the Qiang ethnic‐minority group, 245 the majority Han Chinese group) was conducted in August 2008 in Beichuan county, Sichuan province, a region that was severely affected by the earthquake. In total, 240 households were represented, with a mean of 2.2 respondents per household. Data were collected from structured interviews and the Harvard Trauma Questionnaire (HTQ) and DSM‐IV criteria were used to diagnose PTSD. Results: The prevalence of PTSD was 45.5% (203/446). Low household income, being from an ethnic minority, living in a shelter or temporary house, death in family, and household damage were factors significantly related to increased odds of PTSD. Conclusions: PTSD is common after a major disaster. Postdisaster mental health recovery programs that include early identification, ongoing monitoring, preventive and intervention programs, and sustained psychosocial support are needed for the highest‐risk population, namely, the bereaved, people without incomes and those with serious household damage. These populations may also benefit from governmental and nongovernmental programs that provide social and economic support, as suggested by earlier studies. Depression and Anxiety, 2009. © 2009 Wiley‐Liss, Inc.