Miracle-dz/UniFAR-FTUs huggingface dataset:
Analýza konkurencieschopnosti slovenského spracovateľského priemyslu

The competitive ability of the processing industry in the SR occurs most often in classical types of production characterised by lower level of added value. Commodities with a low added value participate in worsening the balance of trade of the SR. The high export demand of industrial production also contributes to it. The changes in branch structure of processing industry of the SR are continuously reflected in a change of foreign trade structure. Its orientation is on the products less demanding and primarily on raw materials and energetic sources. In spite of this there is visible the tendency to be focused on exports in lower added value products in Slovak processing industry. The worsening of Slovak processing industry status is visible in the commodities where the export is confronted with new industrialized countries production (mainly in textile industry) but also with countries so-called "mono-cultural" (food, drinks, tobacco). In the given examples there is a strong tendency in the SR to lower the trade volume with these commodities. The analysis results show the increase of traffic means in Slovak foreign trade. Automobile industry is coming to the top and it has become the basic branch of the Slovak industry. The trend of development is from one point of view positive not only from the point of view of volume but also from the investment structures from the side of big investors. But on the other hand the SR has become, by this development, more sensible to fluctuation on the world markets. Processing industry is behind in its competitive ability in comparison with high-tech branches. The causes of it are low expenditures for research and development that should be used in these branches and they subsequently cause the low level of creating the level of added value. Marked falling behind in competitive ability of these branches is shown in their low shares in a foreign trade.
Money, Output and Prices in India

The dynamics of the monetary system is undergoing significant changes in India. The entire concept and flow of money; narrow, broad or base, is being influenced by measures related to financial inclusion and also behavioural changes with respect to the increase in usage of plastic money and other payment methods. Given this context, the paper aims to re-examine relationship between money supply, output and prices in the short and long-term. Different metrics for money, output and prices are used to understand the relationship between each. Variables to understand food inflation is especially used considering the fact that food prices are less income elastic and are viewed differently by citizens. The findings indicate that the relationship is sensitive to the choice of variable.
Spatial arrangement of intra-nucleolar rDNA chromatin in amplified Xenopus oocyte nucleoli: structural changes precede the onset of rDNA transcription.

Amphibian oocyte nucleoli are a particular suited object for research on nucleolar chromatin organization. By selective rDNA amplification each pachytene oocyte nucleus accumulates 30 pg of extrachromosomal rDNA, this amount corresponds to 2 million rDNA copies. Following the selective amplification stage, the amplified gene copies are finally distributed within more than thousand extrachromosomal nucleoli per individual oocyte nucleus. The aim of the present study was first to obtain a precise documentation of the fate of amplified rDNA during early Xenopus oogenesis until the final functional integration of these copies into individual oocyte nucleoli, and, second, a close correlation of the structural data with determination of rDNA transcription rates by S1 transcript analysis for the subsequent stages of oocyte differentiation. In order to investigate the structural complexity of the intranuclear rDNA translocation process in detail, a confocal laser scan microscope (CLSM) was used, equipped with an external UV-laser. This instrumentation unambiguously allowed (i) the detection of small clusters of rDNA copies and (ii) the precise spatial documentation of the intranuclear position of rDNA clusters in relation to the protein-free pre-nucleolar protein bodies, a specific characteristic of late pachytene/early diplotene amphibian oocyte nuclei. Our results indicate that the major rDNA translocation processes, e.g. the association of rDNA clusters with pre-nucleolar protein bodies, the formation of ribbon-like pre-nucleolar units sensu Van Gansen and Schramm (J. Cell Sci. 10: 339-367, 1972), and, finally, the translocation of fused rDNA units into the interior of pre-nucleolar protein bodies, occur--for the most part--in absence of massive rDNA transcription. As shown by the S1 transcript analysis, the onset of massive rDNA transcription starts concomitantly with an unraveling of the densely packed rDNA clusters into finely dispersed rDNA units, which were shown by CLSM analysis to be distributed throughout the entire nucleolar volume.
Notice of RetractionThe problem of education investment efficiency and comparison among schools of different levels

It is well known that the resource of education is scarce. This paper constructs a series of Vector error correction model based on the Johansen cointegration test, and then uses the impulse response and variance decomposition method to analyze the dynamic effects on the economic growth among different schools, which are taken as the criterion to evaluate the efficiency of education investment and then helped to figure out the optimum solution to the problem of education investment configuration.
Biomass or growth rate endpoint for algae and aquatic plants: Relevance for the aquatic risk assessment of herbicides

Ecotoxicological studies with algae and aquatic plants are essential parts of the aquatic risk assessment for crop protection products (CPP). Growth rate is used as a response variable and in addition the effects on biomass and/or yield (in the following biomass) can be measured. The parameter biomass generally provides a lower numerical value compared with the growth rate for systematic and mathematical reasons. Therefore, some regulators prefer to use the EbC50 value (i.e., the concentration at which 50% reduction of biomass is observed) rather than ErC50 (the concentration at which a 50% inhibition of growth rate is observed) as the endpoint for ecotoxicological risk assessment. However, the parameter growth rate is scientifically more appropriate and robust against deviations in test conditions, permitting better interpretation of, and comparison between, studies. The aim of the present work is to evaluate the growth rate and biomass parameters with regard to their protectiveness and suitability for environmental risk assessment of CPP. It has been shown for a number of herbicides that the use of the EC50 value (without distinction between growth rate and biomass endpoints) from laboratory studies in combination with an assessment factor of 10 is sufficiently protective for aquatic plants (except for the herbicide 2,4‐D). In this paper we evaluated EbC50 and ErC50 values seperately. Data on 19 different herbicides were compiled from the literature or GLP reports. The EbC50 and ErC50 values obtained in laboratory studies were compared with effect concentrations in ecosystem studies (mainly mesocosm). This comparison of laboratory and field data shows that the overall aquatic risk assessment using ErC50 values in combination with the currently applied assessment factor of 10 is sufficient to exclude significant risk to aquatic plants in the environment. Integr Environ Assess Manag 2011;7:237–247. © 2010 SETAC
Analyst coverage and stock return synchronicity: evidence from regulation changes in China’s IPO market

ABSTRACT This article investigates the relation between analyst coverage and stock return synchronicity in the IPO market. Using a unique data set in China from 2005 to 2012, we find a significantly different effect of analyst coverage on synchronicity before and after the implementation of important 2009 IPO regulation changes in China. Specifically, we document that analyst coverage reduces synchronicity but that this effect is significant only after 2009. In addition, we extend this research to further distinguish the information production role of underwriter and independent analysts. We find that prior to 2009, underwriter analysts’ coverage decreases synchronicity but independent analysts’ coverage does not. However, in the post-2009 period, both types of analyst coverage are significantly and inversely associated with synchronicity. Overall, our results support analysts’ role as producers of firm-specific information in an emerging IPO market and shows that this role depends on the institutional environment.
Repeatability of Radiotracer Uptake in Normal Abdominal Organs with 111In-Pentetreotide Quantitative SPECT/CT

With an increasing emphasis on quantitation of SPECT imaging and its use in dosimetry to guide therapies, it is desirable to understand the repeatability in normal-organ SPECT uptake values (SPECT-UVs). We investigated the variability of normal abdominal organ uptake in repeated 111In-pentetreotide SPECT studies. Methods: Nine patients with multiple 111In-pentetreotide SPECT/CT studies for clinical purposes were evaluated. Volumes of interest were drawn for the abdominal organs and applied to SPECT-UVs. The variability of those values was assessed. Results: The average SPECT-UV for the liver (1.7 ± 0.6) was much lower than for the kidneys (right, 8.0 ± 2.4; left, 7.5 ± 1.7). Interpatient and intrapatient variability was similar (intraclass correlation coefficients, 0.40–0.59) for all organs. The average coefficients of variation for each organ for each patient were obtained and averaged across all patients (0.26 for liver, 0.22 for right kidney, and 0.20 for left kidney). The coefficients of variation for the organs across all scans were 0.33 (liver), 0.30 (right kidney), and 0.22 (left kidney). Conclusion: Variability across all patients and all scans for the liver was higher than reported with 18F-FDG PET, though left kidney variability was similar to PET liver variability and left kidney uptake may be able to serve as an internal metric for determining the quantifiability of an 111In-pentetreotide SPECT study.
Changing the Intensity of Interaction Based on Individual Behavior in the Iterated Prisoner’s Dilemma Game

We present a model of changing the intensity of interaction based on the individual behavior to study the iterated prisoner’s dilemma game in social networks. In this model, each individual has an assessed score of reputation which is obtained by considering the evaluation level of interactive partners for its present behavior. We focus on the effect of evaluation level on the changing intensity of interaction between individuals. For an individual with good behavior, the higher the evaluation level of its partners for its good behavior, the better its reputation, and the higher the probability of surrounding partners interaction with it. On the contrary, for an individual with bad behavior, the lower the evaluation level of its partners for its bad behavior, the worse its reputation, and the less the probability of surrounding neighbors interaction with it. Simulation results show that this effective mechanism can drastically facilitate the emergence and maintenance of cooperation in the population under a treacherous chip. Interestingly, for a small or moderate treacherous chip, the cooperation level monotonously ascends as the evaluation level increases; however, for a higher treacherous chip, existing an optimal evaluation level, which can result in the best promotion of cooperation. Furthermore, we find better agreement between simulation results and theoretical predictions obtained from an extended pair-approximation method, although there are some tiny deviations. We also show some typical snapshots of the system and investigate the reason for appearance and persistence of cooperation. The results further show the importance of evaluation level of individual behavior in coevolutionary relationships.
Induction of 72‐kDa Inducible Heat Shock Protein (HSP72) in Cultured Rat Astrocytes After Energy Depletion

Abstract: Protein synthesis is important in the readaptive processes for cultured astrocytes after hypoxia and subsequent reoxygenation. We have identified 72‐kDa inducible heat shock protein (HSP72) as a major stress protein in reoxygenated astrocytes. To assess the mechanism for reoxygenation‐mediated induction of HSP72, a reporter gene that consists of a human HSP promoter fused to the luciferase gene was transfected into cultured astrocytes. Analysis of cellular energy nucleotides showed an increase of the ADP/ATP ratio after reoxygenation, which synchronized with activation of the HSP promoter. Activation of the HSP promoter was also observed after an addition of iodoacetic acid to hypoxic astrocytes, which reached the maximum when the ADP/ATP ratio reached 50%, but further decline in the energy profile caused inactivation of this promoter. Inhibition of protein synthesis after reoxygenation resulted in temporary restoration of the energy profile and suppression of the DNA binding activity of the heat shock factor. Addition of quercetin greatly decreased the [3H]leucine incorporation in the polysome fraction without any effect on the mature mRNA formation. These data suggest that the energy depletion in reoxygenation triggers induction of HSP72 after reoxygenation, which may act as a pivotal mediator in the stress response of reoxygenated astrocytes by facilitating protein synthesis.
Effect of Waste Engine Oil and Waste Cooking Oil on Performance Improvement of Aged Asphalt

In order to explore the applicability of waste engine oil and waste cooking oil used in aged asphalt, the effect of waste engine oil and waste cooking oil on aged asphalt recycling was studied through the analysis of the improvement of its physical, chemical, and rheological properties. Six aged asphalt binders with different aging times were obtained by indoor test simulation using the Thin Film Oven Test at 163 °C. Then, waste engine oil and waste cooking oil with five different dosages were added to investigate improvement performances. The results clearly demonstrated that waste engine oil and waste cooking oil could soften and recover the work ability of aged asphalt effectively. Furthermore, the physical, chemical, and rheological performances of six aged asphalts could be improved to normal level of virgin asphalt if the content of waste engine oil or waste cooking oil was suitable. The rheological properties of aged asphalt with waste cooking oil had better improvement than that with waste engine oil. Overall, the good applicability would provide waste oil a much wider service range in asphalt pavement recycling field. It also provided a method of developing new rejuvenating agent with the two waste oils to achieve complex synergism effect. Moreover, it realized the waste cyclic utilization and environmental protection.
Interactions with Pocket Proteins Contribute to the Role of Human Papillomavirus Type 16 E7 in the Papillomavirus Life Cycle

ABSTRACT Human papillomaviruses (HPVs), most commonly the HPV16 genotype, are the principle etiological determinant for cervical cancer, a common cancer worldwide resulting in over 200,000 deaths annually. The oncogenic properties of HPVs are attributable in part to the virally encoded protein E7, best known for its ability to bind to and induce the degradation of the retinoblastoma tumor suppressor, pRb, and related “pocket proteins” p107 and p130. Previously, we defined a role for E7 in the productive stage of the HPV16 life cycle, which takes place in stratified squamous epithelia. HPV perturbs the normal processes of cell growth and differentiation of stratified squamous epithelia. HPVs reprogram cells to support continued DNA synthesis and inhibit their differentiation in the suprabasal compartment of the epithelia, where cells normally have withdrawn from the cell cycle and initiated a well-defined pattern of terminal differentiation. These virus-induced perturbations, which contribute to the production of progeny HPVs, are dependent on E7. In this study, we define the mechanism of action by which E7 contributes to the productive stage of the HPV16 life cycle. We found that the ability of HPV16 to reprogram suprabasal cells to support DNA synthesis correlates with E7's ability to bind pocket proteins but not its ability to induce their degradation. In contrast, the ability of HPV16 to perturb differentiation correlated with both E7's binding to and degradation of pocket proteins. These data indicate that different hallmarks of the productive stage of the HPV16 life cycle rely upon different sets of requirements for E7.
Constitutional Reason of State

This paper defends reason of state as an explanatory category. It begins with an analysis of the law relating to the prerogative, before observing that prerogative cases are much less typical today than an expanding suite of cases involving related matters but where the power in question is sourced in statute or the constitution. The long-term historical narrative towards the constitutionalization of reserve powers can thus be expressed as a move from a princely model of reason of state, epitomized by prerogative, to a polity or law-based model of reason of state, whose characteristic form is statute. Locke’s analysis of prerogative is seen as a classic early-modern account of the princely model. Hobbes’s state theory provides the basic script of the polity model, but it is in the republican theorists of the same period, notably Harrington, that we see a recognizably modern concern to normalize reason of state through constitutional and institutional design. The paper then takes issue with modern liberals who follow Hayek in wanting to remove the concept of reason of state from constitutional politics altogether. Such an approach can only work if the state is itself made to vanish, or if a liberal state disengages from interaction with other states. Neither option is plausible. The paper ends with a reflection on the value of the category of reason of state for constitutional theory.
A generative model with hypergraph regularizers for protein function prediction

Heterogeneous data sources and multi-label are two important characteristics of protein function prediction. They describe protein data from two different aspects. However, it is of considerable challenge to integrate multiple data sources and multi-label simultaneously for predicting protein functions, especially when there are only a limited number of labeled proteins. In this paper, we propose a generative model with hypergraph regularizers algorithm, called GMHR, for predicting proteins with multiple functions. The GMHR algorithm integrates all data sources that are available, including protein attribute features, interaction networks, label correlations, and unlabeled data. Experimental results on the real-world datasets predicting the functions of proteins demonstrate the superiority of our proposed method compared with the state-of-the-art baselines.
Influencing variables on life satisfaction of Korean elders in institutions.

PURPOSE The number of elders in institutions has increased as family supporting systems have changed in Korea. The purpose of this study were to understand the life satisfaction among elders in institutions and to identify the factors influencing on life satisfaction. METHODS The instruments used were Yun(1982)'s scale modified Memorial University of Newfoundland Scale for Happiness(MUNSH) in life satisfaction, ADL and IADL in activity level, Self-rating Depression Scale(SDS) in depression and Norbeck Social Support Questionnaire(NSSQ) scale in social support. Also, Perceived health status was measured by Visual Graphic Rating Scale. The subject of this study is 107 cognitively intact and ambulatory elders in 7 institutions in Daegu city and Kyungpook province. The data have been collected from May 1 to June 30, 2001. For the analysis of collected data, frequency analysis, mean, standard deviation, Pearson's correlation and stepwise multiple regression analysis were used for statistical analysis by SPSSwin(version 9.0) program. RESULTS Life satisfaction for the elders in institutions showed negative correlation with SDS, and positive correlation with activity level. The regression form of the stepwise multiple regression analysis to investigate the influencing factors of life satisfaction for the elders in institutions was expressed by y = 90.988-0.733x1-0.188x2-0.069x3-0.565x4 (x1: SDS x2: Social support x3: Activity level x4: Monthly pocket Money) and 57.9% of variance in life satisfaction was explained by the model. CONCLUSION The factors influencing on life satisfaction among the elders in institutions were SDS, social support, activity level and monthly pocket money. According to the results of this study, depression, social support and activity level are considered the prime causal factors for life satisfaction.
Modification of porous aminopropyl-silicate microcapsule membrane by electrically-bonded external anionic polymers

Biocompatibility and permeability of a microcapsule membrane governs the function of a microcapsule-shaped bioartificial pancreas. We have previously developed an alginate/sol-gel-synthesized aminopropyl-silicate/alginate microcapsule (Alg/AS/Alg), which had insufficient biocompatibility. The purpose of this study was to investigate whether the biocompatibility could improve by modifying the external surface with other anionic polymers and to investigate an influence of the modification on the permeability of the membrane. Four kinds of anionic polymers, poly(oxyethylene)diglycolic acid (3 kDa), heparin (15 kDa), Alg (54 kDa) and carboxymethylcellulose (CMC, 60 kDa) were used as the external anionic polymers. The heparin-bonded gel bead had the largest resistance to the diffusion of small molecules. The molecular mass cut-off point of 150 kDa required for immunoisolation was maintained for all anionic polymers. Cellular overgrowth to the implanted islet-enclosing microcapsule, a sign of insufficient biocompatibility, was suppressed by altering the external surface material from Alg to CMC. These results suggest that the biocompatibility of the Alg/AS/anionic polymer membrane can be improved by using a biocompatible anionic polymer. At the same time, it is suggested the influence on the permeability has to be investigated to develop an optimal microcapsule for bioartificial pancreas.
Emerging climate changes and the risks to the operation of building assets in the UK

Purpose – The purpose of this paper is to report results from a survey on emerging climate changes and the risks to the operation of building assets in the UK. The property sector is facing major challenges as a result of projected climate change scenarios. Predictions concerning future climate change and the subsequent impact on building operations are still subject to a high degree of uncertainty. However, it is important that building stockholders consider a range of possible future risks that may influence the operation of their assets. Design/methodology/approach – The literature review and questionnaire are used to elicit and assess the likelihood of occurrence of climate change risks impacting building operations. The survey was carried out among building stockowners and professionals in the UK. Statistical methods were used to rank and compare the findings. Findings – The majority of the respondents strongly agreed that the list of risks that were elicited from the literature will have an impact o.