Miracle-dz/UniFAR-FTUs huggingface dataset:
Evaluation of shellfish consumption in Nha Trang City, Southern coastal Vietnam.

INTRODUCTION Shellfish consumption may be a significant pathway to food contaminants such as heavy metals, pesticides and phycotoxins. Currently, little information exists about consumption of shellfish in Vietnam. Such data could be of interest in terms of nutritional value or risk assessment. METHODS Consumption of shellfish was assessed using a food frequency questionnaire and validated by a 7-day recall method. Approximately 1% of the city population of Nha Trang was selected yielding a final sample of 440 participants. The participants were above 18 years of age, in apparently good health and were shellfish consumers. RESULTS In South coastal Vietnam, the types of shellfish most consumed are green mussel, squid, crab and shrimp. The mean consumption rates of the bivalves, crustaceans, gastropods, cephalopods, echinoderms and all shellfish combined were 39.3, 20.9, 16.4, 11.2, 0.3 and 88.1 g/person/day, respectively. The consumption rate was slightly higher in the age group of 30-54 years, than in the younger (18-29 years) and older (55 years and above) age groups. Shellfish is essentially purchased in the markets and temporary markets, and mostly consumed during the dry season. CONCLUSION Shellfish consumption in the Southern coastal region of Vietnam is high compared to consumption levels in other countries; it is also high compared to consumption levels of Vietnamese emigrants. Such data may be useful for further investigation on nutrition perspectives and in term of risk assessment of shellfish contaminants.
Activity experiences shape perceived fitness trajectories: Results from a 6-month randomized controlled trial in older women

ABSTRACT In this study we addressed the subjective benefits of activity interventions that were designed to improve cognitive fitness in old age. Two hundred and fifty-nine women (aged 70–93 years) were randomized to participate in an exercise or a computer course or a control condition for 6 months. Subjective ratings of the perceived change of cognitive and physical fitness components were captured before, during, after the intervention interval, and at a 10-month follow-up. Positive and negative affect levels and objective cognitive fitness parameters served as possible covariates. Multilevel modeling revealed that the computer group rated memory and concentration as having improved at 4 months and again at 6 months. The exercise group, in contrast, perceived physical capacities as maintained or improved. The characteristics of the activity experience seem to determine the perceived fitness changes. We conclude that actual learning experiences improve one's self-concept of abilities.
Do Financial Market Variables Show (Symmetric) Indicator Properties Relative to Exchange Rate Returns?

This paper assesses the contemporaneous, leading and lagging indicator properties of financial market variables relative to movements in six major developed country currency pairs. As indicator variables changes in various relative asset prices, short-term portfolio flows and currency options data are used. We find that changes in equity index differentials, short-term speculative flows and risk reversals on currency options prices exhibit consistent contemporaneous indicator properties and leading indicator properties for several currency pairs. Since 1999, changes in short-term interest rate differentials have gained importance as indicators. The best indicator variables explain over 50% of monthly returns of the USD/EUR and GBP/USD exchange rates and over 60% of the appreciation and depreciation episodes of the USD/EUR and JPY/EUR currency pairs. JEL Classification: F31, F32, G15
How Neural Network Depth Compensates for HMM Conditional Independence Assumptions in DNN-HMM Acoustic Models

While DNN-HMM acoustic models have replaced GMMHMMs in the standard ASR pipeline due to performance improvements, one unrealistic assumption that remains in these models is the conditional independence assumption of the Hidden Markov Model (HMM). In this work, we explore the extent to which depth of neural networks helps compensate for these poor conditional independence assumptions. Using a bootstrap resampling framework that allows us to control the amount of data dependence in the test set while still using real observations from the data, we can determine how robust neural networks, and particularly deeper models, are to data dependence. Our conclusions are that if the data were to match the conditional independence assumptions of the HMM, there would be little benefit from using deeper models. It is only when data become more dependent that depth improves ASR performance. That performance substantially degrades, however, as the data becomes more realistic suggests that better temporal modeling is still needed for ASR.
Study–Test Congruency Affects Encoding-related Brain Activity for Some but Not All Stimulus Materials

Memory improves when encoding and retrieval processes overlap. Here, we investigated how the neural bases of long-term memory encoding vary as a function of the degree to which functional processes engaged at study are engaged again at test. In an incidental learning paradigm, electrical brain activity was recorded from the scalps of healthy adults while they made size judgments on intermixed series of pictures and words. After a 1-hr delay, memory for the items was tested with a recognition task incorporating remember/know judgments. In different groups of participants, studied items were either probed in the same mode of presentation (word–word; picture–picture) or in the alternative mode of presentation (word–picture; picture–word). Activity over anterior scalp sites predicted later memory of words, irrespective of type of test probe. Encoding-related activity for pictures, by contrast, differed qualitatively depending on how an item was cued at test. When a picture was probed with a picture, activity over anterior scalp sites predicted encoding success. When a picture was probed with a word, encoding-related activity was instead maximal over posterior sites. Activity differed according to study–test congruency from around 100 msec after picture onset. These findings indicate that electrophysiological correlates of encoding are sensitive to the similarity between processes engaged at study and test. The time course supports a direct and not merely consequential role of encoding–retrieval overlap in encoding. However, because congruency only affected one type of stimulus material, encoding–retrieval overlap may not be a universal organizing principle of neural correlates of memory.
Frequency of Clinically Occult Intraepithelial and Invasive Neoplasia in Reduction Mammoplasty Specimens: A Study of 516 Cases

Reduction mammoplasty is a frequently performed procedure for the treatment of macromastia and for the achievement of symmetry in breast cancer patients following lumpectomy. Slides from 516 consecutive bilateral reduction mammoplasties performed for macromastia over 15 years were reviewed. Among these, 92 (18%) low-risk ductal intraepithelial neoplasia/intraductal hyperplasia, 28 (5%) ductal intraepithelial neoplasia 1 (1 low-grade ductal carcinoma in situ, 11 atypical intraductal hyperplasia, and 16 flat type), 17 (3%) lobular intraepithelial neoplasia, and 1 (0.2%) tubular carcinoma were identified. The patients were categorized into 3 age groups: <40 (n = 352), 40 to 50 (n = 107), and over 50 years (n = 57); the frequency of the lesions increased with age. These data confirm the low frequency of clinically occult malignancies identified in reduction mammoplasty specimens and provide substantial information about the frequency of a variety of intraepithelial proliferations. Preoperative mammography, specimen orientation, and inking of margins with 1 color are advised when reduction mammoplasty is scheduled for women ≥ 40 years of age.
Prospects for cannabinoids as anti‐inflammatory agents

The marijuana plant (Cannabis sativa) and preparations derived from it have been used for medicinal purposes for thousands of years. It is likely that the therapeutic benefits of smoked marijuana are due to some combination of its more than 60 cannabinoids and 200–250 non‐cannabinoid constituents. Several marijuana constituents, the carboxylic acid metabolites of tetrahydrocannabinol, and synthetic analogs are free of cannabimimetic central nervous system activity, do not produce behavioral changes in humans, and are effective antiinflammatory and analgesic agents. One cannabinoid acid in particular, ajulemic acid, has been studied extensively in in vitro systems and animal models of inflammation and immune responses. This commentary reviews a portion of the work done by investigators interested in separating the medicinal properties of marijuana from its psychoactive effects. Understanding the mechanisms of the therapeutic effects of nonpsychoactive cannabinoids should lead to development of safe effective treatment for several diseases, and may render moot the debate about “medical marijuana”. © 2002 Wiley‐Liss, Inc.
Invariance Properties of Solow&Apos;S Productivity Residual

In 1957, Robert Solow published a paper that provided the theoretical foundation for almost all subsequent work on productivity measurement. Although most applications of Solow's method have measured trends over fairly long time periods, the method also has important uses at higher frequencies. Under constant returns to scale and competition, the Solow residual measures the pure shift of the production function. Shifts in product demand and factor supplies should have no effect on the residual. Tests of this invariance property show that it fails in a great many industries. Though other explanations may deserve some weight, it appears that the leading cause of the failure of invariance is increasing returns and market power. The empirical findings give some support to the theory of monopolistic competition.
Abnormalities of granule cell dendritic structure are a prominent feature of the intrahippocampal kainic acid model of epilepsy despite reduced postinjury neurogenesis

Purpose: Aberrant plastic changes among adult‐generated hippocampal dentate granule cells are hypothesized to contribute to the development of temporal lobe epilepsy. Changes include formation of basal dendrites projecting into the dentate hilus. Innervation of these processes by granule cell mossy fiber axons leads to the creation of recurrent excitatory circuits within the dentate. The destabilizing effect of these recurrent circuits may contribute to hyperexcitability and seizures. Although basal dendrites have been identified in status epilepticus models of epilepsy associated with increased neurogenesis, we do not know whether similar changes are present in the intrahippocampal kainic acid model of epilepsy, which is associated with reduced neurogenesis.
Domain Mapping of the Polycystin-2 C-terminal Tail Using de Novo Molecular Modeling and Biophysical Analysis*

In polycystic kidney disease (PKD), polycystin-2 (PC2) is frequently mutated or truncated in the C-terminal cytoplasmic tail (PC2-C). The currently accepted model of PC2-C consists of an EF-hand motif overlapping with a short coiled coil; however, this model fails to explain the mechanisms by which PC2 truncations C-terminal to this region lead to PKD. Moreover, direct PC2 binding to inositol 1,4,5-trisphosphate receptor, KIF3A, and TRPC1 requires residues in PC2-C outside this region. To address these discrepancies and investigate the role of PC2-C in PC2 function, we performed de novo molecular modeling and biophysical analysis. De novo molecular modeling of PC2-C using the ROBETTA server predicts two domains as follows: an EF-hand motif (PC2-EF) connected by a linker to a previously unidentified C-terminal coiled coil (PC2-CC). This model differs substantially from the current model and correlates with limited proteolysis, matrix-assisted laser desorption/ionization mass spectroscopy, N-terminal sequencing, and improved coiled coil prediction algorithms. PC2-C is elongated and oligomerizes through PC2-CC, as measured by analytical ultracentrifugation and size exclusion chromatography, whereas PC2-EF is globular and monomeric. We show that PC2-C and PC2-EF have micromolar affinity for calcium (Ca2+) by isothermal titration calorimetry and undergo Ca2+-induced conformational changes by circular dichroism. Mutation of predicted EF-hand loop residues in PC2 to alanine abolishes Ca2+ binding. Our results suggest that PC2-CC is involved in PC2 oligomerization, and PC2-EF is a Ca2+-sensitive switch. PKD-associated PC2 mutations are located in regions that may disrupt these functions, providing structural insight into how PC2 mutations lead to disease.
The Effects of Reputation and Relationships on Lead Banks’ Certification Roles

We investigate the certification roles of lead bank retention in US syndicated loans with respect to interest rates, then explore how lead banks' reputation and previous relationships with the borrower alter such certification effects. Our findings support the certification hypothesis. Loan spreads are found to decrease with a higher retention ratio, after controlling for the endogeneity of loan price and retention. The magnitude of certification effect is reduced when the lead bank is a more reputable lender and when there are prior bank-borrower relationships. Lead bank reputation and prior lending relationships can therefore substitute for the need to certify.
The Theory of Vertical Integration: A Survey and Synthesis

This article is concerned with the role of theory in explaining the inter‐industry variation of vertical integration (VI). Why, for example, is the world aluminium industry highly integrated (Stukey, 1983) whereas the tin industry is not (Hennart, 1982)? The article is not concerned with explaining differences in the average level of VI across countries, although these are undoubtedly significant (Chandler and Daeins, 1980).
Contextual Influences on Participation in U. S. State Legislative Elections

Participation by voters in the election of U. S. state legislators varies significantly across legislative districts. This analysis of state legislative elections in Iowa and California in 1978 demonstrates the powerful effects which campaign and partisan competitiveness can have on the extent to which voters take part in choosing their state legislator. With participation rates as the dependent variables, this study establishes a multivariate model which includes variables for campaign spending, the closeness of the electoral contests, the extent of district partisanship, and the degree of party competition. These "political mobilization" factors are shown to contribute very substantially to explaining variations in participation.
The relationship between the backscattering coefficient and the biomass of narrow and broad leaf crops

The influence of the shape and dimensions of plant constituents on the backscattering of agricultural vegetation is investigated. Multifrequency multitemporal polarimetric data, collected at C- and L-bands by means of airborne and satellite synthetic aperture radar (SAR), showed that the relations between the backscattering of crops and the vegetation biomass depend on plant type, and that there are different trends for "narrow" and "broad" leaf crops. In the latter crops, backscattering increases with an increase in the biomass, especially at L-band. This behavior is typical of media in which scattering is dominant, whereas on "narrow leaf" plants, the trend is flat or decreasing, denoting a major contribution of absorption. Theoretical simulations obtained with a discrete element radiative transfer model have confirmed that a different backscattering of crops with the same biomass may be due to plant geometry.
The Progress Principle: Using Small Wins to Ignite Joy, Engagement, and Creativity at Work

The Progress Principle: Using Small Wins to Ignite Joy, Engagement, and Creativity at Work Teresa M. Amabile and Steven J. Kramer (Boston, MA: Harvard Business Review Press, 2010) In The Progress Principle, Teresa Amabile and Steven Kramer masterfully summarize the findings of their work about the impact of everyday work life on creativity and performance. Based on rigorously designed behavioral experiments, Amabile and Kramer present clear evidence that challenges conventional approaches to employee motivation. "The best way to motivate people, day in and day out," they find, is not with conventional motivators, such as performance bonuses, but "by facilitating progress. " Based on that finding, they recommend that corporate leaders reshape their roles from being managers of people--recruiting, motivating, developing, evaluating, rewarding--to facilitators of progress, focused on helping people succeed at moving forward with meaningful work. Managers and leaders must take an active role in ensuring that employees have rewarding inner work lives by removing obstacles to progress. Seven companies from the high-tech, consumer products, and chemical industries participated in the authors' study, with an average of four teams participating per company. The companies were very diverse, ranging from young startups to established companies, small to large. A total of 11,637 daily surveys were completed by 238 employees over an average of 19 weeks. The individual participants were highly educated--about 82% had at least a college degree and some had graduate education--with a mean age of 38 years. This profile is representative of the contemporary knowledge worker, giving the book immediate relevance for current managers. The central idea of The Progress Principle is that meaningful accomplishments have a strong positive impact on an employee's inner work life and a positive inner work life drives performance. Here is how the progress principle works. Our inner work life comprises our emotions, perceptions, and motivations; creativity, the authors found, is correlated to all three. Positive emotions enhance creativity, as does a positive perception of the work environment; employees intrinsically motivated by interesting, enjoyable, and challenging work are more creative. All three dimensions are positively affected when we achieve small wins and breakthroughs, reach goals, and get the feeling that we are moving forward. However, Amabile and Kramer discovered that simply getting tasks done is not enough to guarantee a good inner work life. For the progress principle to operate, the work must be meaningful to the person doing it. Here, what matters is not any objective notion of value, but that we perceive that our work is contributing value to something or someone. …
Early use of mammalian target of rapamycin inhibitors is an independent risk factor for incisional hernia development after liver transplantation

Incisional hernias (IHs) are common complications after liver transplantation (LT) with a reported incidence of 1.7% to 34.3%. The purpose of this retrospective study was to evaluate the risk factors for IH development after LT with a focus on the role of immunosuppressive therapy during the first month after LT. We analyzed 373 patients who underwent LT and divided them into 2 groups according to their postoperative course: an IH group (121 patients or 32.4%) and a no‐IH group (252 patients or 67.6%). A univariate analysis demonstrated that the following were risk factors related to IH development: male sex (P = 0.03), a body mass index ≥ 29 kg/m2 (P = 0.005), LT after 2004 (P = 0.02), a Model for End‐Stage Liver Disease (MELD) score ≥ 22 (P = 0.01), and hepatitis B virus infection (P = 0.01). The highest incidence of IHs was found in patients treated with mammalian target of rapamycin (mTOR) inhibitors (54.5%, P = 0.004). A multivariate analysis revealed male sex (P = 0.03), a pretransplant MELD score ≥ 22 (P = 0.04), and the use of mTOR inhibitors (P = 0.001) to be independent risk factors for IHs after LT. In conclusion, immunosuppressive therapy with mTOR inhibitors is an important independent risk factor for IH development after LT. To reduce the incidence of IHs, mTOR inhibitors should be avoided until the fourth month after LT unless their use is deemed to be strictly necessary. Liver Transpl 18:188–194, 2012. © 2011 AASLD.
Governance and organisational controls in public and private banks

Managers of a sample of private and public banks in Greece were surveyed through the vehicle of agency theory. It was found that managers in private banks showed greater alignment of interests with those of the bank, their pay related to outcomes and they were more mobile in their jobs. Private banks also used more control mechanisms to align interests of their managers with those of the bank and displayed a different working climate. Given evolving organisation structures resulting from deregulation, the convergence of information technology and communications and the entry of firms from other industries, the implications of the findings for governance are important.
Sensor selection cost optimisation for tracking structurally cyclic systems: a P-order solution

ABSTRACT Measurements and sensing implementations impose certain cost in sensor networks. The sensor selection cost optimisation is the problem of minimising the sensing cost of monitoring a physical (or cyber-physical) system. Consider a given set of sensors tracking states of a dynamical system for estimation purposes. For each sensor assume different costs to measure different (realisable) states. The idea is to assign sensors to measure states such that the global cost is minimised. The number and selection of sensor measurements need to ensure the observability to track the dynamic state of the system with bounded estimation error. The main question we address is how to select the state measurements to minimise the cost while satisfying the observability conditions. Relaxing the observability condition for structurally cyclic systems, the main contribution is to propose a graph theoretic approach to solve the problem in polynomial time. Note that polynomial time algorithms are suitable for large-scale systems as their running time is upper-bounded by a polynomial expression in the size of input for the algorithm. We frame the problem as a linear sum assignment with solution complexity of .
Dynamics of Self-monitoring and Error Detection in Speech Production: Evidence from Mental Imagery and MEG

Abstract A critical subroutine of self-monitoring during speech production is to detect any deviance between expected and actual auditory feedback. Here we investigated the associated neural dynamics using MEG recording in mental-imagery-of-speech paradigms. Participants covertly articulated the vowel /a/; their own (individually recorded) speech was played back, with parametric manipulation using four levels of pitch shift, crossed with four levels of onset delay. A nonmonotonic function was observed in early auditory responses when the onset delay was shorter than 100 msec: Suppression was observed for normal playback, but enhancement for pitch-shifted playback; however, the magnitude of enhancement decreased at the largest level of pitch shift that was out of pitch range for normal conversion, as suggested in two behavioral experiments. No difference was observed among different types of playback when the onset delay was longer than 100 msec. These results suggest that the prediction suppresses the response to normal feedback, which mediates source monitoring. When auditory feedback does not match the prediction, an “error term” is generated, which underlies deviance detection. We argue that, based on the observed nonmonotonic function, a frequency window (addressing spectral difference) and a time window (constraining temporal difference) jointly regulate the comparison between prediction and feedback in speech.