Miracle-dz/UniFAR-FTUs huggingface dataset:
High-Gain, Circularly-Polarized THz Antenna With Proper Modeling of Structures With Thin Metallic Walls

In the paper, a corporate feed antenna array with slot radiators and a layer of polarizing patches is designed to operate at 350 GHz. The antenna is conceived as a silicon structure fully metalized by gold. Different methods for modeling thin gold layers at terahertz frequencies are compared and the optimum approaches are chosen depending on the thickness of the metal layer and its relation to the skin depth. Two designed antenna arrays are in <inline-formula> <tex-math notation="LaTeX">$2\times 2$ </tex-math></inline-formula> and <inline-formula> <tex-math notation="LaTeX">$4\times 4$ </tex-math></inline-formula> configuration, radiate circularly polarized waves, and have high gains of 13.8 dBic and 18.4 dBic, respectively. Antenna arrays have a low profile of only <inline-formula> <tex-math notation="LaTeX">$1.3~\lambda _{0. }$ </tex-math></inline-formula> Cheaper and more available manufacturing technology is presented and discussed in detail together with the measurement results of three manufactured prototypes. Small deviations between the simulated results and the measured ones are obtained due to a lower surface roughness, which is confirmed by the scanning probe microscope. Comparison with state-of-the-art antenna arrays demonstrates that the proposed arrays excel in easy/low-cost manufacturing, high gain, circular polarization with good axial-ratio bandwidth, compact size, and the possibility to easily extend the array into a larger version.
Autopsy on active distribution networks: A data-driven fault analysis using micro-PMU data

In this paper, we conduct a data-driven experimental analysis on a single-phase-to-neutral fault at a distribution grid in Riverside, CA using data from five distribution level phasor measurement units, a.k. a, Micro-PMUs. Of particular interest is to extract the time-line during the fault. With the high resolution, precision, and time synchronization of the data from Micro-PMUs, the hypothesis about optimal operation of protection devices during each period of the fault time-line is examined, followed by exploring the success of coordination between lateral fuse and main feeder recloser. Also, this paper studies the transient effect of fault on the load-level as well as feeder-level. In addition, the response of inverter based resources to fault, specifically to islanding, is observed and the miscoordination between anti-islanding protection of PV inverters and the feeder recloser is deduced. Finally, the effect of the fault on outlying area feeder-level and customer-level is investigated. This paper takes a first step in using micro-PMU data to conducting a detailed analysis, an autopsy, of how different voltage levels are affected by fault switching events in distribution systems.
New protocol for immune tolerance induction in acquired hemophilia.

BACKGROUND AND OBJECTIVES Immune tolerance induction (ITI) regimens with human factor VIII concentrates are rarely if ever implemented in adult patients with auto-inhibitors, in contrast to alloantibody suppression, which is used primarily in young children with congenital hemophilia. On the basis of some earlier experience with synchronization of plasma exchange therapy of various autoimmune disorders we have developed a new aggressive protocol for the treatment of patients with acquired factor VIII (FVIII) antibody. We have evaluated the outcome of 14 consecutive nonhemophilic FVIII inhibitor patients treated in a single center with our ITI protocol between 1992 and 1999, comparing them to 6 historical control patients, treated with traditional immunosuppression therapy (steroid +/- cyclophosphamide) between 1988 and 1992. DESIGN AND METHODS Our ITI protocol consists of three weeks of treatment with 1) human FVIII concentrates (30 U/kg/day for the 1st week, 20 U/kg/day for the 2nd, and 15 U/kg/day for the 3rd week), plus 2) iv. cyclophosphamide (200mg/day to a total dose of 2-3 grams), plus 3) methylprednisolone (100 mg/day iv. for one week and than tapering down the dose gradually over the next two weeks). The treatment of acute bleeding episodes in the two groups was not different. High purity and ultra-high purity factor VIII concentrates were used for the ITI. We performed aPTT and mixing tests before and after two hours of incubation, Bethesda inhibitor assay, porcine FVIII cross-reactivity, FVIII:C before and after FVIII administration (recovery), three times a week. The sex ratio and mean age (64 years for the ITI group versus 57 years for the controls), the initial and peak inhibitor titers, and residual FVIII: C values at the diagnosis were similar in the two groups. RESULTS Eradication of the inhibitor occurred in 13/14 patients in the ITI vs. 4/6 patients in the control group. The main difference between the two groups was in the time needed for the complete disappearance of the inhibitor (4.6 weeks for ITI vs. 28.3 weeks for controls). In the ITI group we have observed only two relapses during the relatively long follow-up period (26 months), and in both cases the same re-induction protocol was successful again. No bleeding-related mortality occurred in this group in contrast to that of 33% in the controls. Apart from the well-known adverse effects of glucocorticoid therapy, we have observed only one patient with transient cytopenia. We have not seen any adverse event which could be attributed to the use of FVIII concentrates. INTERPRETATION AND CONCLUSIONS We conclude that the ITI protocol described here is highly effective for the treatment of acquired hemophilia, induces quick therapeutic responses and favorably influences the underlying autoimmune disorder. We suggest that our ITI protocol is suitable for the eradication of idiopathic and autoimmune-associated FVIII autoantibodies in patients presenting with severe bleeding.
Influence of Peri-Operative Hypothermia on Surgical Site Infection in Prolonged Gastroenterological Surgery.

BACKGROUND There have been several recent studies on the correlation between intra-operative hypothermia and the occurrence of surgical site infection (SSI). Differences in the depth and timing of hypothermia and the surgical procedure may have led to conflicting results. METHODS Patients undergoing gastroenterologic surgery with a duration of >3 h were analyzed. Hypothermia was defined as a core temperature <36°C and was classified as mild (35.5-35.9°C), moderate (35.0-35.4°C), or severe (<35.0°C). Hypothermia also was classified as early-nadir (<36°C within two h of anesthesia induction) and late-nadir (after that time). Risk factors for SSIs were analyzed according to these classifications. RESULTS Among 1,409 patients, 528 (37.5%) had hypothermia, which was classified as mild in 358, moderate in 137, and severe in 33. Early-nadir and late-nadir hypothermia was found in 23.7% and 13.8%, respectively. There was no significant difference in the incidence of SSIs between patients with and without hypothermia (relative risk 1.00; 95% confidence interval [CI] 0.80-1.25; p = 0.997). However, there was a significantly greater incidence of SSIs in patients with severe hypothermia (33.3%) than in those with normothermia (19.2%; p = 0.045) or mild hypothermia (17.0%; p = 0.021). The incidence of SSIs also was significantly greater in patients with late-nadir than in those with early-nadir hypothermia (23.7% vs. 16.5%; p = 0.041). The incidence of organ/space SSIs was significantly greater in patients with late-nadir hypothermia (19.6%) than in patients with normothermia (12.7%; p = 0.012). In multivariable analysis, neither severe hypothermia (odds ratio 1.24; 95% CI 0.56-2.77] nor late-nadir hypothermia (OR 0.71; 95% CI 0.46-1.01) was an independent risk factor for SSIs. CONCLUSIONS Severe and late-nadir hypothermia were associated with a greater incidence of SSIs and organ/space SSIs. However, neither of these patterns was identified as an independent risk factor for SSIs, possibly because of the small number of patients.
On the asymptotics of degree distributions

In random graph models, the degree distribution of individual nodes should be contrasted against the degree distribution of the graph, i.e., the usual fractions of nodes with given degrees. We introduce a general framework to discuss conditions under which these two degree distributions coincide asymptotically in large random networks. Somewhat surprisingly, we show that even in strongly homogeneous random networks, this equality may fail to hold. This is done by means of a counterexample drawn from the class of random threshold graphs. An implication of this finding is that random threshold graphs cannot be used as a substitute to the Barabási-Albert model for scale-free network modeling, as proposed by some authors.
Parallel similarity joins on massive high‐dimensional data using MapReduce

In this paper, we focus on high‐dimensional similarity join (HDSJ) using MapReduce paradigm. As the volume of the data and the number of the dimensions increase, the computation cost of HDSJ will increase exponentially. There is no existing effective approach that can process HDSJ efficiently, so we propose a novel method called symbolic aggregate approximation (SAX)‐based HDSJ to deal with the problem. SAX is the abbreviation of symbolic aggregate approximation that is a dimensionality reduction technique and widely used in time series processing, we use SAX to represent the high‐dimensional vectors in this paper and reorganize these vectors into groups based on their SAX representations. For the very high‐dimensional vectors, we also propose an improved SAX‐based HDSJ approach. Finally, we implement SAX‐based HDSJ and improved SAX‐based HDSJ on Hadoop‐0.20. 2 and perform comprehensive experiments to test the performance, we also compare SAX‐based HDSJ and improved SAX‐based HDSJ with the existing method. The experiment results show that our proposed approaches have much better performance than that of the existing method. Copyright © 2015 John Wiley & Sons, Ltd.
In vitro function of platelets treated with ultraviolet C light for pathogen inactivation: a comparative study with nonirradiated and gamma‐irradiated platelets

During storage of platelet concentrates (PCs) replication of contaminating pathogens might occur, which can be prevented by various pathogen inactivation (PI) methods using photoactive substances in combination with ultraviolet (UV) light. A new method uses only UVC light for PI without photoactive substances. This study evaluates the in vitro function, including hemostatic properties (clot formation and elasticity), of platelets (PLTs) treated with UVC light.
“Do Unto Others As…” - Which Treatments do Psychiatrists Prefer?

We undertook an independent national survey of psychiatrists' treatment preferences should they become mentally ill. The response rate was 59% from 921 individuals. For psychosis, atypical antipsychotics were generally favoured with risperidone receiving most votes. Psychotherapy and antidepressants were both endorsed as treatments for mild-tomoderate depression, and citalopram, fluoxetine and venlafaxine were the three preferred antidepressants. ECT received the backing of a large majority of psychiatrists, particularly for severe mood disorder.
Poster: IsoRAN: Isolation and Scaling for 5G RAN via User-Level Data Plane Virtualization

5G presents a unique set of challenges for cellular network architecture. The architecture needs to be versatile in order to handle a variety of use cases. In this paper we propose IsoRAN, a design for 5G Cloud RAN(CRAN) which provides isolation and scaling along with the flexibility needed for 5G architecture through fine-grained slicing. Our design allows users with diverse service requirements to be executed on the most efficient hardware, to ensure that the Service Level Agreements(SLA) are met while minimizing power consumption. Our experiments show that IsoRAN handles users with different SLA while providing isolation to reduce interference. This increased isolation reduces the drop rate for different users from 42% to nearly 0% in some cases while requiring only half the amount of resources.
Low Prevalence of Chronic Beryllium Disease Among Workers at a Nuclear Weapons Research and Development Facility

Objective: To study the prevalence of beryllium sensitization (BeS) and chronic beryllium disease (CBD) in a cohort of workers from a nuclear weapons research and development facility. Methods: We evaluated 50 workers with BeS with medical and occupational histories, physical examination, chest imaging with high-resolution computed tomography (N = 49), and pulmonary function testing. Forty of these workers also underwent bronchoscopy for bronchoalveolar lavage and transbronchial biopsies. Results: The mean duration of employment at the facility was 18 years and the mean latency (from first possible exposure) to time of evaluation was 32 years. Five of the workers had CBD at the time of evaluation (based on histology or high-resolution computed tomography); three others had evidence of probable CBD. Conclusions: These workers with BeS, characterized by a long duration of potential Be exposure and a long latency, had a low prevalence of CBD.
The Correlation of ATP-binding Cassette 1 mRNA Levels with Cholesterol Efflux from Various Cell Lines*

Studies show that lipid-free apoA-I stimulates release of cholesterol and phospholipid from fibroblasts and macrophages. ATP-binding cassette 1 (ABC1) is implicated in this release and has been identified as the genetic defect in Tangier disease, evidence that ABC1 is critical to the biogenesis of high density lipoprotein. We quantified levels of ABC1 mRNA, protein, and cholesterol efflux from J774 mouse macrophages ± exposure to a cAMP analog. Up-regulating ABC1 mRNA correlated to increased cholesterol efflux in a dose- and time-dependent manner. mRNA levels rose after 15 min of exposure while protein levels rose after 1 h, with increased efflux 2–4 h post-treatment. In contrast to cells from wild-type mice, peritoneal macrophages from the Abc1 −/− mouse showed a lower level of basal efflux and no increase with cAMP treatment. The stimulation of efflux exhibits specificity for apoA-I, high density lipoprotein, and other apolipoproteins as cholesterol acceptors, but not for small unilamellar vesicles, bile acid micelles, or cyclodextrin. We have studied a number of cell types and found that while other cell lines express ABC1 constitutively, only J774 and elicited mouse macrophages show a substantial increase of mRNA and efflux with cAMP treatment. ApoA-I-stimulated efflux was detected from the majority of cell lines examined, independent of treatment.
Phylogenetic and Functional Classification of the Photolyase/Cryptochrome Family

The photolyase/cryptochrome (PHR/CRY) family is a large group of proteins with similar structure but very diverge functions such as DNA repair, circadian clock resetting and regulation of transcription. As a result of advances in the biochemistry of the CRY/PHR family and identification of new members, several adjustments have been made to the classification of this protein family. For example, a new class of PHRs, Class III, has been proposed. Furthermore, CRYs have been suggested to function as photosensory proteins in the primordial eye of sponge larvae. Additionally, a magnetosensory function has been attributed to certain CRYs. Recent advances in the field enabled us to propose a comprehensive classification scheme and nomenclatural system for this family. This review focuses on the computational and biochemical classifications of the PHR/CRY family. Several examples show that computational analysis can give a hinge about the function of newly discovered members before performing any biochemical study.
Latency Requirements for Foveated Rendering in Virtual Reality

Foveated rendering is a performance optimization based on the well-known degradation of peripheral visual acuity. It reduces computational costs by showing a high-quality image in the user’s central (foveal) vision and a lower quality image in the periphery. Foveated rendering is a promising optimization for Virtual Reality (VR) graphics, and generally requires accurate and low-latency eye tracking to ensure correctness even when a user makes large, fast eye movements such as saccades. However, due to the phenomenon of saccadic omission, it is possible that these requirements may be relaxed. In this article, we explore the effect of latency for foveated rendering in VR applications. We evaluated the detectability of visual artifacts for three techniques capable of generating foveated images and for three different radii of the high-quality foveal region. Our results show that larger foveal regions allow for more aggressive foveation, but this effect is more pronounced for temporally stable foveation techniques. Added eye tracking latency of 80--150ms causes a significant reduction in acceptable amount of foveation, but a similar decrease in acceptable foveation was not found for shorter eye-tracking latencies of 20--40ms, suggesting that a total system latency of 50--70ms could be tolerated.
Personality Profiling from Text: Language Features Tied to Personality across Corpora

Studies that correlate personality with language features use homogeneous data sets from a single domain, such as Facebook posts, emails from one company, and student essays from one university. Such single-domain correlations may not generalize well to other domains. Therefore it is important to study which language features are associated with personality across multiple domains. This paper reports preliminary results from the first such cross-domain study of correlations between personality and language usage.
Nebular spectra and abundance tomography of the Type Ia supernova SN 2011fe: a normal SN Ia with a stable Fe core

A series of optical and one near-infrared nebular spectra covering the first year of the Type Ia supernova SN 2011fe are presented and modelled. The density profile that proved best for the early optical/ultraviolet spectra, "rho-11fe", was extended to lower velocities to include the regions that emit at nebular epochs. Model rho-11fe is intermediate between the fast deflagration model W7 and a low-energy delayed-detonation. Good fits to the nebular spectra are obtained if the innermost ejecta are dominated by neutron-rich, stable Fe-group species, which contribute to cooling but not to heating. The correct thermal balance can thus be reached for the strongest [FeII] and [FeIII] lines to be reproduced with the observed ratio. The 56Ni mass thus obtained is 0.47 +/- 0.05 Mo. The bulk of 56Ni has an outermost velocity of ~8500 km/s. The mass of stable iron is 0.23 +/- 0.03 Mo. Stable Ni has low abundance, ~10^{-2} Mo. This is sufficient to reproduce an observed emission line near 7400 A. A sub-Chandrasekhar explosion model with mass 1.02 Mo and no central stable Fe does not reproduce the observed line ratios. A mock model where neutron-rich Fe-group species are located above 56Ni following recent suggestions is also shown to yield spectra that are less compatible with the observations. The densities and abundances in the inner layers obtained from the nebular analysis, combined with those of the outer layers previously obtained, are used to compute a synthetic bolometric light curve, which compares favourably with the light curve of SN 2011fe.
Molecular characterisation of JC virus strains detected in human brain tumours

Aims: The aim of this study was to evaluate the presence and significance of JC virus (JCV) in human brain tumours. Methods: Histology, immunohistochemistry (IHC) and molecular biology techniques were employed to examine specimens of tumour tissue, peripheral blood and cerebrospinal fluid taken from 22 patients with primary neuro‐epithelial tumours. Furthermore, the coding viral protein (VP1) region and non‐coding transcription control region (TCR) of JCV genome isolated from the tumours were submitted to sequence analysis in order to detect viral rearrangements or mutations. Results: JCV genome was found in nine of the 22 tumour specimens (40.9%), including eight astrocyte‐derived tumours (seven glioblastomas and one astrocytoma) and one oligodendroglioma, and in two of the 15 cerebrospinal fluid specimens (13.3%) with positive tumour tissue (one glioblastoma and one astrocytoma). Sequence analysis of JCV VP1, which was amplified in seven tissue samples and the two cerebrospinal fluid samples, revealed only genotype 1 (four 1a and three 1b), whereas TCR was amplified in six tissue samples and only one cerebrospinal fluid sample. TCR sequence analysis was possible in four cases and identified three Mad‐4 and one type II sequences; the TCR genomic structures of JCV isolated from cerebrospinal fluid were the same as those sequenced from corresponding tumour tissue, thus indicating a possible cerebrospinal fluid dissemination of neoplastic cells carrying viral DNA. Conclusions: Our results suggest a possible role of JCV in the induction of brain tumours, especially in those originating from brain cells normally targeted by JCV infection.
Ageratum enation virus Infection Induces Programmed Cell Death and Alters Metabolite Biosynthesis in Papaver somniferum

A previously unknown disease which causes severe vein thickening and inward leaf curl was observed in a number of opium poppy (Papaver somniferum L.) plants. The sequence analysis of full-length viral genome and associated betasatellite reveals the occurrence of Ageratum enation virus (AEV) and Ageratum leaf curl betasatellite (ALCB), respectively. Co-infiltration of cloned agroinfectious DNAs of AEV and ALCB induces the leaf curl and vein thickening symptoms as were observed naturally. Infectivity assay confirmed this complex as the cause of disease and also satisfied the Koch’s postulates. Comprehensive microscopic analysis of infiltrated plants reveals severe structural anomalies in leaf and stem tissues represented by unorganized cell architecture and vascular bundles. Moreover, the characteristic blebs and membranous vesicles formed due to the virus-induced disintegration of the plasma membrane and intracellular organelles were also present. An accelerated nuclear DNA fragmentation was observed by Comet assay and confirmed by TUNEL and Hoechst dye staining assays suggesting virus-induced programmed cell death. Virus-infection altered the biosynthesis of several important metabolites. The biosynthesis potential of morphine, thebaine, codeine, and papaverine alkaloids reduced significantly in infected plants except for noscapine whose biosynthesis was comparatively enhanced. The expression analysis of corresponding alkaloid pathway genes by real time-PCR corroborated well with the results of HPLC analysis for alkaloid perturbations. The changes in the metabolite and alkaloid contents affect the commercial value of the poppy plants.
'Mechanical' neural learning and InfoMax orthonormal independent component analysis

We present a new class of learning models for linear as well as nonlinear neural learners, deriving from the study of the dynamics of an abstract rigid mechanical system. The set of equations describing the motion of this system may be readily interpreted as a learning rule for orthogonal networks. As a simple example of how to use the learning theory, a case of the orthonormal independent component analysis based on the Bell-Sejlunoski's InfoMax principle is discussed through simulations.