Miracle-dz/UniFAR-FTUs huggingface dataset:
The Difficulty of Centering Circular Discs

Centering, positioning an object within specified bounds, is a common computer task, for example making selections using a touch screen or positioning icons relative to each other. The experiments measured times for participants (n = 155) to position a circular cursor with diameter, p = 40 pixel or approximately 10 mm, completely within circular targets with a variety of diameters, w. The analysis divides the total movement time into two parts, the time for the cursor to touch the target and the centering time, the remaining time for participants to indicate that the cursor is completely within the target by clicking on the mouse button. The time to touch the target is modeled well by the initial cursor-target separation, and the centering time is modeled well by the index of difficulty, ID C = p/(w-p). Both models have high correlation, r 2 = 0.99.
Cash & carry sector : location models and GIS decision support

VI Chapter 1 The Problem and Its Setting 1 1.1 The Importance of Location Decision in Retail 1 1.2 Cash and Carry / Warehouse Club: An Important and 2 Under-considered Sector 1.3 Objectives of the Thesis 5 Chapter 2 Retail Location Literature Review 8 2.1 Retail Location Theory 8 2.2 Retail Location Models 12 2.3 Retail Location Applications and Spatial Data 16 Chapter 3 Spatial Data and Geographic Information Systems (GIS) 19 3.1 Development and Application of GIS 19 3.2 The Features and Structure of GIS 21 3.3 Consumer Spatial Data and GIS 26 3.4 Components of GIS 36 Chapter 4 Location Model for Cash & Carry / Warehouse Club 40 4.1 Model Selection 40 4.2 Type Selection 42 4.3 Criteria for Measuring Goodness of Fit 43 4.4 Statistics Package Selection 44
Cardiac rehabilitation program in patients with Chagas heart failure: a single-arm pilot study.

INTRODUCTION The benefit of a cardiac rehabilitation (CR) program for patients with Chagas heart failure (CHF) remains unclear. Therefore, we aimed to investigate the effects of CR for CHF patients. METHODS A single-arm pilot study, including 12 patients with CHF, was performed. Patients participated in an 8-month physical exercise intervention, comprising aerobic, strength, and stretching exercises (3 times per week, 60 minutes per session). Nutritional and pharmaceutical counseling were also performed. Functional capacity (cardiopulmonary exercise test), muscle respiratory strength (manovacuometry), and body composition (anthropometry and skinfolds) were evaluated at baseline, and after 4 and 8 months of intervention. Cardiac function (echocardiography), biomarkers (lipid profile, glucose, and glycated hemoglobin) and quality of life (Minnesota Living with Heart Failure Questionnaire) were assessed at baseline and at the end of the intervention. RESULTS Seven of 12 patients included in the study completed the 8-month follow-up period. Only 2 moderate adverse events occurred during the exercise training. Functional capacity improved after 4 months of CR, while left ventricular ejection fraction (LVEF) and respiratory strength improved after 8 months. Patients with right ventricular (RV) dysfunction at baseline exhibited an improvement in functional capacity after 4 months, and improvements in left ventricular (LV) diastolic pressure, respiratory strength, and quality of life at the end of follow-up. Conversely, those with normal baseline RV function demonstrated LVEF increases that were not observed in patients with RV dysfunction. CONCLUSIONS CR was feasible, safe, and has important clinical benefits for patients with CHF, specifically for cardiac function and muscle respiratory strength.
International Conference on Emerging Ubiquitous Systems and Pervasive Networks ( EUSPN 2017 ) ProximiThings : Implementing Proxemic Interactions in the Internet of Things

Proxemic dimensions can help mediate interactions between entities (people, objects) in Internet of Things environments and constitute an important element in the construction of proactive, context-aware and human-centric systems. However, as evidenced by the literature, little attention has been paid to implementing proxemic interactions in IoT platforms. We present ProximiThings, a framework for facilitating the incorporation of proxemic capabilities in IoT-based systems. We describe the construction of various prototypes to show how ProximiThings can be used by developers in real settings. c 2016 he uthors. Published by Elsevier B.
Evaluation of Tear Meniscus Dynamics Using Anterior Segment Swept-Source Optical Coherence Tomography After Topical Solution Instillation for Dry Eye

Purpose: To investigate tear meniscus dynamics using anterior segment swept-source optical coherence tomography (SS-OCT) after the instillation of topical solutions for dry eye. Design: Prospective, observational, cross-sectional study. Methods: Thirty-six healthy subjects (28 men and 8 women; mean age, 34.4 ± 6.7 years) were enrolled in this study. The lower tear meniscus height, tear meniscus area, and tear meniscus volume were assessed using anterior SS-OCT. After baseline measurements, 40 &mgr;L of 0.1% sodium hyaluronate, 0.3% sodium hyaluronate, 3% diquafosol ophthalmic solution, or 2% rebamipide ophthalmic solution was instilled in one eye of 10 subjects each, whereas 40 &mgr;L saline was instilled in the other eye. Tear meniscus measurements were obtained using SS-OCT at 30 seconds and 1, 3, 5, 10, 15, 20, and 30 minutes after instillation. Results: The tear meniscus measurements showed a significant increase until 1, 3, 10, 10, and 3 minutes after the instillation of saline, 0.1% sodium hyaluronate, 0.3% sodium hyaluronate, 3% diquafosol, and 2% rebamipide, respectively, compared with the baseline levels (P < 0.05). Compared with those after saline instillation, the tear meniscus measurements were significantly higher until 30 seconds and 3, 30, and 15 minutes after the instillation of 0.1% sodium hyaluronate, 0.3% sodium hyaluronate, 3% diquafosol, and 2% rebamipide, respectively (P < 0.05). Conclusions: The instillation of ophthalmic solutions for the treatment of dry eye greatly increased tear meniscus measurements in healthy subjects. Thus, SS-OCT can be a practical tool for the quantitative evaluation of early-phase tear fluid dynamics.
Benchmarks for SPARQL Property Paths

The Resource Description Framework (RDF) is a triple based representation of directed graphs with labelled edges. With the emergence of RDF graphs special databases, called RDF stores, were developed. In order to query graphs, which are stored in these RDF stores, the query language SPARQL Protocol And Query Language (SPARQL) is used. With the help of this query language it is possible to describe subgraphs with a fixed number of edges, containing the desired information. In march 2013 SPARQL 1.1 was released. The newly introduced property paths make it possible to describe subgraphs with an arbitrary amount of edges. This feature was implemented into the different RDF stores. In order to compare the implementations of property paths of the different RDF stores a set of metrics is needed. Benchmarks can provide such metrics. The development of such a benchmark and the comparison of different RDF stores based on this benchmark are the substance of this bachelor thesis.
Bladder diary patterns in detrusor overactivity and urodynamic stress incontinence

Our aims were: (1) to describe and compare frequency‐volume and incontinence episode patterns in patients with urodynamic stress incontinence (USI) and detrusor overactivity (DO) as measured by a hand‐written and computer‐analyzed bladder diary and (2) to compare degree of separation between these clinical groups produced by raw diary measurements and after age‐ and total‐volume‐adjustment against a reference population.
Convolutional Neural Networks for Sentiment Classification on Business Reviews

Recently Convolutional Neural Networks (CNNs) models have proven remarkable results for text classification and sentiment analysis. In this paper, we present our approach on the task of classifying business reviews using word embeddings on a large-scale dataset provided by Yelp: Yelp 2017 challenge dataset. We compare word-based CNN using several pre-trained word embeddings and end-to-end vector representations for text reviews classification. We conduct several experiments to capture the semantic relationship between business reviews and we use deep learning techniques that prove that the obtained results are competitive with traditional methods.
A Coupled Mathematical Model for a Temperature Dependant Blood Perfusion in Heterogeneous Biological Tissues during Microwave Heating

Problem statement: The temperature variation in heterogeneous three layered biological tissues was investigated. Approach: The blood perfusion was considered to be temperature dependent. The heating modalities were taking to go on simultaneously in each of the regions on the one hand and also sequentially in another arrangement. The asymptotic series solution was modified for the three layers and the matching were done at the interface of the regions where there is electric field effect and where there is none. Results: The result revealed there was a clear difference from the temperature pattern when the heating modality was done simultaneously compared to when done sequentially. The thickness of the tissues layer has effect on temperature pattern. Conclusion: A lot of attention must be taken to determine tissue thermophysical properties before therapy was applied. The regional body heating was preferred to spare surrounding normal tissue as against the whole body heating procedure.
PAS domain residues involved in signal transduction by the Aer redox sensor of Escherichia coli

PAS domains sense oxygen, redox potential and light, and are implicated in behaviour, circadian rhythmicity, development and metabolic regulation. Although PAS domains are widespread in archaea, bacteria and eukaryota, the mechanism of signal transduction has been elucidated only for the bacterial photo sensor PYP and oxygen sensor FixL. We investigated the signalling mechanism in the PAS domain of Aer, the redox potential sensor and aerotaxis transducer in Escherichia coli. Forty‐two residues in Aer were substituted using cysteine‐replacement mutagenesis. Eight mutations resulted in a null phenotype for aerotaxis, the behavioural response to oxygen. Four of them also led to the loss of the non‐covalently bound FAD cofactor. Three mutant Aer proteins, N34C, F66C and N85C, transmitted a constant signal‐on bias. One mutation, Y111C, inverted signalling by the transducer so that positive stimuli produced negative signals and vice versa. Residues critical for signalling were mapped onto a three‐dimensional model of the Aer PAS domain, and an FAD‐binding site and ‘active site’ for signal transduction are proposed.
Nutritional requirements of Methanomicrobium mobile

A defined medium was developed for Methanomicrobium mobile BP. M. mobile required acetate for growth; the optimal concentration was 30 mM. Other requirements and their optimal concentrations included isobutyrate (0.65 mM), isovalerate (0.73 mM), and 2-methylbutyrate (1.5 mM). The appropriate branched-chain amino acids did not substitute for these branched-chain fatty acids. M. mobile required tryptophan at an optimal concentration of 24 microM. Indole substituted for tryptophan, but the possible precursor compounds shikimic acid and anthranilic acid and the degradation compound skatole did not. Vitamin requirements and their optimal concentrations included pyridoxine (0.49 microM), thiamine (0.15 microM), biotin (0.04 microM), and vitamin B12 (0.04 microM); p-aminobenzoic acid (0.18 microM) was required for optimal growth, but folic acid did not replace p-aminobenzoic acid. M. mobile required an unidentified growth factor found in ruminal fluid or extracts of Methanobacterium thermoautotrophicum for growth. M. mobile has a complex nutrition compared with that of other methanogens, but not an unusual nutrition in the context of organisms from the ruminal ecosystem.
Strategies for Reducing Professional Turnover in Information Technology

Strategies for Reducing Professional Turnover in Information Technology by Brett Grosshans MS, Jones International University, 2009 BS, University of Iowa, 1984 Doctoral Study Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Business Administration Walden University October 2018 Abstract The information technology (IT) industry workforce in the United States is expected to increaseThe information technology (IT) industry workforce in the United States is expected to increase by approximately 50,000 jobs through the year 2024, creating opportunities for employees to change jobs if they are not satisfied. Replacing talented IT professionals can cost a business as much as 150% of the salary of the outgoing employee. The purpose of this descriptive single case study was to identify strategies successful IT business leaders used to reduce voluntary turnover among IT professionals. The research population was 4 leaders from an IT business in southeastern Virginia, who oversee supervisory and hiring. The conceptual framework was Herzberg’s 2-factor theory. The data were collected using semistructured interviews and reviews of applicable organization documents. Yin’s 5 phases of analysis were the means to process the data resulting in the 5 themes of flexibility, individual, recognition, team, and work-life balance. Recognition and flexibility were the 2 key themes that made significant contributions to the organizational culture and success for the business. The implications for social change include companies using unspent replacement cost dollars to invest in local communities, improve the local economic growth, and provide incentives for employee quality of life and improved work environment. Strategies for Reducing Professional Turnover in Information Technology by
Pd-Catalyzed Cyanation of (Hetero)Aryl Halides by Using Biphosphine Ligands.

Tetraadamantylbiphosphine (TABP; L1), which showed superior activity in the palladium-catalyzed cyanation of 4-chloroanisole compared to standard phosphines, was synthesized as a new ligand. The generality of the new catalytic system was shown by the cyanation reaction of approximately 30 (hetero)aryl halides including hindered, electron-rich, and electron-poor aryl chlorides. These reactions constitute the first examples of using biphosphine ligands in Pd-catalyzed coupling reactions.
Aprotinin and the risk of thrombotic complications after liver transplantation: A retrospective analysis of 1492 patients

Aprotinin is an antifibrinolytic drug that reduces blood loss during orthotopic liver transplantation (OLT). Case reports have suggested that aprotinin may be associated with an increased risk of thromboembolic complications. Recent studies in cardiac surgery also have suggested a higher risk of renal failure and postoperative mortality. Despite these concerns, no large‐scale safety assessment has been performed in OLT. In a retrospective observational study involving 1492 liver transplants, we studied the occurrence of postoperative thromboembolic or thrombotic events and mortality in patients who received aprotinin (n = 907) and patients who did not (n = 585). The overall incidence of hepatic artery thrombosis and central venous complications (pulmonary embolism or inferior vena cava thrombosis) was 3.2% and 0.9%, respectively. In propensity score–adjusted analyses (C‐index = 0.79), aprotinin was not associated with an increased risk of hepatic artery thrombosis [odds ratio (OR) = 1.00, 95% confidence interval (CI) = 0.50‐2.01, P = 0.86]. Although central venous complications were found more frequently in patients receiving aprotinin, the difference was not statistically significant (OR = 2.95, 95% CI = 0.54‐16.23, P = 0.32). In addition, no significant differences were found in 1‐year mortality (OR = 1.21, 95% CI = 0.86‐1.71, P = 0.32). In conclusion, this study did not demonstrate an increased risk of thrombotic complications or mortality when aprotinin is used during OLT. Liver Transpl 15:747–753, 2009. © 2009 AASLD.
Orthopaedic device-related infection: current and future interventions for improved prevention and treatment

Orthopaedic and trauma device-related infection (ODRI) remains one of the major complications in modern trauma and orthopaedic surgery. Despite best practice in medical and surgical management, neither prophylaxis nor treatment of ODRI is effective in all cases, leading to infections that negatively impact clinical outcome and significantly increase healthcare expenditure. The following review summarises the microbiological profile of modern ODRI, the impact antibiotic resistance has on treatment outcomes, and some of the principles and weaknesses of the current systemic and local antibiotic delivery strategies. The emerging novel strategies aimed at preventing or treating ODRI will be reviewed. Particular attention will be paid to the potential for clinical impact in the coming decades, when such interventions are likely to be critically important. The review focuses on this problem from an interdisciplinary perspective, including basic science innovations and best practice in infectious disease. Cite this article: Moriarty TF, Kuehl R, Coenye T, et al. Orthopaedic device related infection: current and future interventions for improved prevention and treatment. EFORT Open Rev 2016;1:89-99. DOI: 10.1302/2058-5241.1. 000037.
Trends and Availability of Suicide Methods in Finland

Background Trends and availability of the methods used for suicide in Finland were analysed in order to base proposals for prevention of access to methods. Methods Finnish suicides from 1947 to 1990 were analysed by sex, age, time period and suicide method using confidence intervals for rates, χ2 test for trends and suicide risks for different medicines. Results Suicide rate by parathion, a highly lethal pesticide and commonly used for suicide in the 1950s, decreased after its availability was restricted, but this was offset by an increased rate by other methods. Since 1982, the suicide risk for antidepressants and neuroleptics increased coincident with their availability, although that for barbiturates remained stable but high despite a reduction in availability. Suicide risk for antidepressants other than tricyclics decreased despite increased availability. Conclusion Restriction of a method reduces its use for suicide, but other methods tend to replace it. Restrictive measures should focus on some specific situations. Antidepressants other than tricyclics are recommended for the treatment of suicidal depressive patients.
Compact ACS-Fed Printed Antenna Using Dual Edge Resonators for Tri-Band Operation

A novel compact asymmetric coplanar strip (ACS)-fed printed antenna using dual edge resonators for tri-band operation is presented. The proposed tri-band antenna is based on an ACS-fed beveled monopole, to which an E-shaped coupled resonator and an L-shaped slot resonator are introduced for achieving two new independent resonances and miniaturization of size. The antenna has a small overall dimensions of only 12 × 23 × 1 mm3. The experimental results demonstrate the proposed antenna is capable of operating over the frequency ranges 2.37-2.52, 3.38-3.71, and 4.92-5.96 GHz, suitable for 2.4/5.2/5.8-GHz WLAN and 3.5/5.5-GHz WiMAX applications.
Success in Innovation: Improving the Odds by Understanding the Factors for Unsuccess

Success in Innovation tackles its subject from a novel perspective: instead of focusing on factors for success, it specifically examines the factors for failure. Similar books often attempt to stimulate more effort on innovation with success stories and methods. But innovation is risky business and most innovative ideas fail. By understanding the typical pitfalls and hurdles in the process, and how to avoid or manage them, readers can significantly improve their chances of success. Success in Innovation is broad in scope and useful to managers, consultants, entrepreneurs, tech start-ups - anyone with a stake in new and powerful ideas, products, businesses, or methods. This book helps readers work smarter, not simply more. Provides guidelines for assessing innovative ideas Includes methods for valuing innovation Discusses the danger points in the innovation process Explains the planning and development processes Includes innovation models Discusses the methods for risk assessment
Hemorrhagic symptoms and bleeding risk in obligatory carriers of type 3 von Willebrand disease: an international, multicenter study

Summary. Objectives: We undertook an international, multicenter study to describe the clinical picture and to estimate the bleeding risk in a group of obligatory carriers of type 3 von Willebrand disease (VWD). Patients and methods: Obligatory carriers (OC) of type 3 VWD were identified by the presence of offspring with type 3 VWD or by being an offspring of a type 3 patient. Normal controls were age‐ and sex‐matched with the obligatory carriers. A physician‐administered standardized questionnaire was used to evaluate hemorrhagic symptoms at presentation. A score system ranging from 0 (no symptom) to 3 (hospitalization, replacement therapy, blood transfusion) was used to quantitate bleeding manifestations. Odds ratios were computed for each symptom. Results: Ten centers participated to the study, enrolling a total of 35 type 3 VWD families, with 70 OC. A total of 215 normal controls and 42 OC for type 1 VWD were also included. About 40% of type 3 OC had at least one bleeding symptom compared to 23% of normal controls and 81.8% of type 1 OC (P < 0.0001 by chi‐squared test), showing that type 3 OC clearly represent a distinct population from type 1 OC. The clinical situations associated with an increase of bleeding risk in type 3 OC were epistaxis [odds ratio 3.6; 90% confidence intervals (CI) 1.84–21.5], cutaneous bleeding (odds ratio 5.5; 90% CI 2.5–14.1) and postsurgical bleeding (odds ratio 16.3; 90% CI 4.5–59). The severity of bleeding score correlated with the degree of factor (F) VIII reduction in plasma. Conclusions: OC for type 3 VWD represent a distinctive population from type 1 OC. These patients, however, present with more frequent bleeding symptoms in comparison to normal controls, especially in case of significantly low FVIII. Desmopressin and/or tranexamic acid might be useful to prevent or treat bleeding in these cases.