Miracle-dz/UniFAR-FTUs huggingface dataset:
Bipedal robot walking pattern generation based on capture point and minimizing falling damage for posture recovery

Bipedal walking is one of the core issues of humanoid robots. We generated bipedal walking pattern based on the capture point. Capture point is stable criterion so we can generate desired zero moment point by the capture point and generate center of mass trajectory using the preview control. We also generated the safety fall down & stably get up motion when capture point is out of the stable region.
Coronary Arterial Revascularization in an Adult with Congenitally Corrected Transposition of Great Arteries and Dextrocardia

Abstract Objectives:Congenitally corrected transposition of great arteries with dextrocardia is an extremely rare lesion in adulthood. This group of patients does not live long enough for atherosclerotic coronary artery disease processes, because of existing comorbid anomalies. Methods: We report a 47‐year‐old man with isolated congenitally corrected transposition of great arteries, dextrocardia, and athersclerotic coronary artery disease. The patient underwent coronary artery revascularization with cardiopulmonary bypass. The free left internal mammary artery (LIMA) was grafted to the tiny left anterior descending artery (LAD), and the reversed saphenous vein Y graft was anastomosed to the posterior descending and posterolateral branches of the morphologic right coronary artery. Results: The patient recovered uneventfully. He is alive and well 24 months after the surgery. Conclusions: To our knowledge, the present case is the first congenitally corrected transposition of great arteries with dextrocardia treated with grafted coronary artery bypass. Early and full revascularization is very important for the systemic right ventricle exposed to a systemic workload. The vessel pathologies and technical details of this unusual case are discussed in this paper.
Validity and Reliability of a Self-administered Food Frequency Questionnaire to Assess Vitamin K Intake in Korean Adults

This study was conducted to validate a food frequency questionnaire (FFQ) to assess vitamin K intake in clinical and research settings based on data from the Fifth Korea National Health and Nutrition Examination Survey (KNHANES V). We collected a subset of data on informative food items using the 24-hour recall method from adults aged 19 to 64 years from KNHANES V. The cumulative percent contribution and cumulative multiple regression coefficients for vitamin K intake from each food were computed. Twenty-five foods items were selected for the FFQ to assess vitamin K intake. The FFQ was validated against intakes derived from a 5-day food record (5DR) (n = 48). To assess the reliability of the FFQ, participants completed the self-administered FFQ (FFQ1) and a second FFQ (FFQ2) after a 6-month period (n = 54). Data were analyzed using Pearson's correlation coefficients, the cross-classification method, and Bland-Altman plots. Mean intakes were similar for vitamin K between the FFQ and dietary records, with significant correlations observed (r = 0.652), and cross-classification analyses demonstrated no major misclassification of participants into intake quartiles. Bland-Altman plots showed no serious systematic bias between the administrations of the two dietary assessment methods over the range of mean intakes. FFQ reliability was high, with a Pearson's correlation coefficient of 0.560. This pilot study shows promising validation and reliability evidence for the use of this FFQ, which is focused on vitamin K intake in adults, as an efficient screening tool in clinical and research settings.
Fermentation pattern of methanogenic degradation of rice straw in anoxic paddy soil.

The anaerobic degradation of different fractions of rice straw in anoxic paddy soil was investigated. Rice straw was divided up into stem, leaf sheath and leaf blade. The different straw fractions were mixed with paddy soil and incubated under anoxic conditions. Fermentation of straw components started immediately and resulted in transient accumulation of acetate, propionate, butyrate, isobutyrate, valerate, isovalerate and caproate with much higher concentrations in the presence than in the absence of straw. Also some unidentified compounds with UV absorption could be detected. The maximum concentrations of these compounds were different when using different straw fractions, suggesting differences in the degradation pathway of these straw fractions during the early phase of incubation, i.e. with Fe(III) and sulfate serving as oxidants. When concentrations of the intermediates decreased to background values, CH(4) production started. Rates of CH(4)unamended soil. During the methanogenic phase, the percentage contribution of fermentation products to CH(4) production was determined by inhibition with 2-bromoethanesulfonate (BES). Acetate (48-83%) and propionate (18-28%) were found to be the main intermediates of the carbon flow to CH(4), irrespective of the fraction of the rice straw or its absence. Mass balance calculations showed that 84-89% of CH(4) was formed via acetate in the various incubations. Radiotracer experiments showed that 11-27% of CH(4) was formed from H(2)/CO(2), thus confirming that acetate contributed 73-89% to methanogenesis. Our results show that the addition of rice straw and the fraction of the straw affected the fermentation pattern only in the early phase of degradation, but had no effect on the degradation pathway during the later methanogenic phase.
Internal Carotid Artery Dissection After Remote Surgery: Iatrogenic Complications of Anesthesia

Background Subintimal dissection with acute occlusion of the internal carotid artery resulting in acute cerebral infarction has not been reported as an iatrogenic complication of general anesthesia. Case Descriptions An anesthetist stretched the neck of a 44-year-old man by anchoring an anesthesia mask posterior to the angle of the jaw with overlying fingers as the patient struggled during an insufficient inhalational mask anesthetic. A 33-year-old man received an endotracheal anesthetic without struggle, but as he was turned from a supine to a prone position, his head and neck were not immobilized to rotate with his torso during the move. The next day both patients suffered acute cerebral infarctions secondary to ICA dissections and occlusions (angiographically demonstrated). Conclusions Stretching the soft neck tissues of anesthetized patients can cause internal carotid artery dissection and acute cerebral infarction.
DT56a (Femarelle) stimulates bone formation in female rats

Objective DT56a is a natural compound for the treatment of menopausal symptoms and osteoporosis. The aim of this study was to examine the effects of long term treatment (two months) with DT56a on the skeletal tissues of intact and ovariectomised (OVX) adult rats.
Pathogenesis of familial Parkinson’s disease: new insights based on monogenic forms of Parkinson’s disease

Parkinson’s disease (PD) is one of the most common movement disorders caused by the loss of dopaminergic neuronal cells. The molecular mechanisms underlying neuronal degeneration in PD remain unknown; however, it is now clear that genetic factors contribute to the pathogenesis of this disease. Approximately, 5% of patients with clinical features of PD have clear familial etiology, which show a classical recessive or dominant Mendelian mode of inheritance. Over the decade, more than 15 loci and 11 causative genes have been identified so far and many studies shed light on their implication in not only monogenic but also sporadic form of PD. Recent studies revealed that PD‐associated genes play important roles in cellular functions, such as mitochondrial functions, ubiquitin‐proteasomal system, autophagy‐lysosomal pathway and membrane trafficking. Furthermore, the proteins encoded by PD‐associated genes can interact with each other and such gene products may share a common pathway that leads to nigral degeneration. However, their precise roles in the disease and their normal functions remain poorly understood. In this study, we review recent progress in knowledge about the genes associated with familial PD.
Interaction of cytoplasmic membrane and ribosomes in Escherichia coli: spectinomycin-induced disappearance of membrane protein I-19

Incubation of Escherichia coli with spectinomycin caused the disappearance of a major protein from the cytoplasmic membrane. This protein, called "I-19", was not a ribosomal protein. Its disappearance was not a result of the direct action of spectinomycin on the cytoplasmic membrane, but a result of its action on ribosomes. The disappearance was specifically induced by spectinomycin, and other antibiotics such as neomycin, erythromycin, and chloramphenicol had no effect. Although growth was not required for spectinomycin-induced disappearance of protein I-19 from the cytoplasmic membrane, the disappearance was not observed under conditions where protein synthesis was inhibited completely either by the addition of chloramphenicol or by cooling in ice. It is suggested that at least some ribosomes interact with the cytoplasmic membrane and that a modification of the mode of interaction through the action of spectinomycin on ribosomes caused the deletion of membrane protein I-19.
Determination of DNA sequence changes induced by ethyl methanesulfonate in human cells, using a shuttle vector system

The DNA sequence changes for 54 mutations induced in human cells by the alkylating agent ethyl methanesulfonate are reported. The mutations were obtained by using a shuttle vector system with the bacterial lacI gene as the target. Of the 54 mutations obtained, 53 were G:C to A:T transitions.
MIMO Amplify-And-Forward Relaying: Spatial Gain and Filter Matrix Design

In this paper we investigate and analyze the performance of multi-antenna amplify-and-forward (AF) relays for a future cellular system where the destination and the source form a MIMO system. Two scenarios are analyzed, modelled and compared: the multi-relay scenario i.e. distributed relays, each equipped with at least one antenna; and the one-relay scenario i.e. a single relay in a sector where each relay is equipped with multiple antennas. The optimal filter coefficients applied at the relays are derived and recommended for both cases. The channel ergodic capacity and by product the throughput of the single link shows that the AF relay matched filter based performs best in the multi-relay scenario. On other hand the relay based singular value decomposition (SVD) is more suitable for the one-relay scenario.
Genetic Loss of Faah Compromises Male Fertility in Mice1

Abstract Marijuana is the most commonly used illicit drug. Although there is some indication that reproductive functions in males are impaired in chronic marijuana users, the genetic evidence and underlying causes remain largely unknown. Herein we show that genetic loss of Faah, which encodes fatty acid amide hydrolase (FAAH), results in elevated levels of anandamide, an endocannabinoid, in the male reproductive system, leading to compromised fertilizing capacity of sperm. This defect is rescued by superimposing deletion of cannabinoid receptor 1 (Cnr1). Retention of Faah−/− sperm on the egg zona pellucida provides evidence that the capacity of sperm to penetrate the zona barrier is hampered by elevated anandamide levels. Collectively, the results show that aberrant endocannabinoid signaling via CNR1 impairs normal sperm function. Besides unveiling a new regulatory mechanism of sperm function, this study has clinical significance in male fertility.
Financial Ratios as Indicators of Economic Sustainability: A Quantitative Analysis for Swiss Dairy Farms

In agriculture, a rising number of sustainability assessments are available that also comprise financial ratios. In a literature review of farm management textbooks, taking account of the differences between European and North American practices and considering prevalent sustainability assessment approaches, we identified frequently used financial ratios. Five ratios relate to the indicator profitability and four to the indicator liquidity. Another eight financial indicators refer to the indicators financial efficiency, stability, solvency and repayment capacity. Based on more than 14,000 accountancies of dairy farms from the Swiss Farm Accountancy Data Network (FADN), we carried out a Spearman correlation analysis for normalised and harmonised financial ratios. The correlation analysis revealed mostly positive correlations. To assess the implementation of a quantitative economic sustainability assessment we compare an aggregated indicator compound of all 17 ratios with two selections of financial ratios–first, a compound European and, second, a compound North American economic sustainability indicator. The correlation between the complete and the reduced sets of indicators suggest that both aggregate economic indicators can be reasonably applied to estimate the economic sustainability for Swiss dairy farms.
A Purpose-Based Typology for Systemic Features Enabling Value Co-Creation in Consumer Information Systems

Value co-creation enabled by consumers' use of information systems is a challenging topic which requires more explicit definitions for use of academics and managers. Systemic features are digital services enabling co-creation of value, not being products or services to be paid for, but assisting as consumer-supporting capabilities between different contexts. In order to gain better insight for systemic features within information systems, we collected empirical data from 23 firms in the high-tech sector and analyzed the systemic features. Systemic features were classified and prioritized by a research group. The created purpose-based typology enhances the understanding on why and how value is co-created with customers. We contribute both to systems and business research by suggesting a purpose-based typology defining different purpose-based constructs for systemic features enabling co-creation of value. We also discuss implications for managing and organizing value within the firm and contribution to organization science and theory of the firm.
Impact of the Main Currencies Exchange Rates on the Romanian Economic Policy Transformation

Evolutions of the exchange rates in a contemporary competitive economy represent an influential marker in evaluating the effects of the governmental policies in field of monetary policy and marks future directions in developing the specific policies in the field. This study investigates how the exchange rates of EUR, USD, GBP and CHF were influenced by disturbing factors and the existence of potential quantitative correlations and dependencies among the four exchange rates in terms of uncertainty.
Exchange Rate Pass-through to Domestic Prices in Thailand, 2000-2017

This paper explores the degree of exchange rate pass-through to domestic prices in Thailand using quarterly data from 2000Q1 to 2017Q4. Johansen cointegration tests are employed in the analysis. The degree of exchange rate pass-through is found to be partial and modest. The stable pass-through effect in the long-run is found for import price index. The findings give some implications for risk perception by firms and investors regarding the future inflationary environment of the country.
Nucleolar protein upstream binding factor is sequestered into adenovirus DNA replication centres during infection without affecting RNA polymerase I location or ablating rRNA synthesis

When human adenovirus infects human cells there is disruption of rRNA biogenesis. This report examines the effect of adenovirus infection on the nucleolar protein, upstream binding factor (UBF) which plays a major role in regulating rRNA synthesis. We determined that early after infection, UBF associates with the replication of viral DNA, preferentially associating with the ends of the linear viral genome, and that addition of anti-UBF serum to in vitro replication assays markedly reduced viral DNA replication. Regions of UBF important to these observations are also established. Interestingly, sequestering the majority of UBF from the nucleolus did not lead to the ablation of rRNA synthesis or the sequestration of RNA pol I. In infected cells the bulk of RNA synthesis was RNA pol I associated and distinct from the location of most of the detectable UBF. We propose that UBF plays a role in viral DNA replication, further strengthening the role of nucleolar antigens in the adenovirus life cycle.
Walking Phase Modulates H-Reflex Amplitude in Flexor Carpi Radialis

ABSTRACT It is well established that remote whole-limb rhythmic movement (e.g., cycling or stepping) induces suppression of the Hoffman (H-) reflex evoked in stationary limbs. However, the dependence of reflex amplitude on the phase of the movement cycle (i.e., phase-dependence) has not been consistent across this previous research. The authors investigated the phase-dependence of flexor carpi radialis (FCR) H-reflex amplitudes during active walking and in kinematically matched static postures across the gait cycle. FCR H-reflexes were elicited in the stationary forearm with electrical stimulation to the median nerve. Significant phase-dependent modulation occurred during walking when the gait cycle was examined with adequate phase resolution. The suppression was greatest during midstance and midswing, suggesting increased ascending communication during these phases. There was no phase-dependent modulation in static standing postures and no correlation between lower limb background electromyography levels and H-reflex amplitude during active walking. This evidence, along with previous research demonstrating no phase modulation during passive walking, suggests that afferent feedback associated with joint position and leg muscle activation levels are not the sole source of the phase modulation seen during active walking. Possible sources of phase modulation include combinations of afferent feedback related to active movement or central motor commands or both.
A combination of spatial and spectral filters for mental condition discrimination

It is widely accepted that the common spatial pattern (CSP) analysis method, albeit being very popular in brain-computer interface (BCI) applications as a feature extraction method for binary classification, is vulnerable to artifact. It could underperform when it is exposed to an input whose frequency band is too broad that many interfering frequency components are contained. These drawbacks are closely related to the nature of CSP filters which are based on completely spatial weighting. That is, CSP has no control on the temporal space of brain signals. This work is one attempt to extend CSP by eliminating the undesirable temporal components through spectral filtering. The proposed method in this work retains the simplicity of CSP but derives a number of complex spatial and spectral integrated filters by applying multiple time lags and a regularization term. These filters are data-driven and channel-specific. Their ability to narrow the frequency band of signals so as to enhance feature extraction is demonstrated using a public available dataset, where 4.7% higher mean classification accuracy is achieved.
The Relationship between Teacher Support and Students' Academic Emotions: A Meta-Analysis

This meta-analysis examines the association between teacher support and students' academic emotions [both positive academic emotions (PAEs) and negative academic emotions (NAEs)] and explores how student characteristics moderate these relationships. We identified 65 primary studies with 58,368 students. The results provided strong evidence linking teacher support and students' academic emotions. Furthermore, students' culture, age, and gender moderated these links. The correlation between teacher support and PAEs was stronger for Western European and American students than for East Asian students, while the correlation between teacher support and NAEs was stronger for East Asian students than for Western European and American students. Also, the correlation between teacher support and PAEs was strong among university students and weaker among middle school students, compared to other students. The correlation between teacher support and NAEs was stronger for middle school students and for female students, compared to other students.
Food insecurity and hunger safety net use among single-room occupancy tenants in San Francisco, CA

ABSTRACT We used a cross-sectional survey to explore the prevalence of food insecurity and use of hunger safety net programs, as well as the extent that they are associated, among 595 single-room occupancy tenants living within high-poverty neighborhoods in San Francisco, CA. The population was primarily male (73%) and over 55 years old (59%). 84% were classified as food insecure. 46% used free grocery programs, 44% used free dining rooms, and 34% used free home-delivered meals. Adjusted regressions estimated an inverse relationship (OR 0.91, 95% CI: 0.8, 1.0) between free home-delivered meals and food insecurity, suggesting a potential protective association.
Energy, Timing and Position Resolution Studies With 16-Pixel Silicon Photomultiplier Matrices for Small Animal PET

A high resolution small animal PET scanner that employs Silicon Photomultiplier (SiPM) matrices as photodetectors is under development at the University of Pisa and INFN Pisa. The first SiPM matrices fabricated by the Center for Scientific and Technological Research, FBK-irst (Trento, Italy), are being evaluated for this purpose. The devices are composed of 16 (4 times4) pixel elements of 1 mmtimes1 mm in a common substrate. The first tests have been carried out employing the ASIC MAROC2 for the readout. Energy and timing resolution, and position determination tests have been performed coupling both pixellated and continuous LYSO scintillator crystals to the matrix, and the results have been compared with the ones obtained for single SiPMs. The first tests on position determination with continuous crystals and SiPM matrices have been performed. An intrinsic spatial resolution of 0.61 mm FWHM has been obtained.
Twelve-month, open-label assessment of long-term safety and abuse potential of hydrocodone extended-release formulated with abuse-deterrence technology in patients with chronic pain.

OBJECTIVE To evaluate long-term safety of hydrocodone extended-release (ER) formulated with CIMA(®) Abuse-Deterrence Technology platform. DESIGN Phase 3, open-label study. SETTING Sixty-one US study centers. PATIENTS Patients with chronic pain newly enrolled or rolled over from a 12-week, placebo-controlled hydrocodone ER study; 330 patients enrolled, 329 patients received study drug, and 189 completed the study. INTERVENTION After titrating to an analgesic dose (15-90 mg every 12 hours), patients received ≤ 52 weeks of open-label treatment. MAIN OUTCOME MEASURES SAFETY adverse events (AEs), vital signs, laboratory values, electrocardiograms, and audiometry. Abuse potential: drug loss and diversion, Screener and Opioid Assessment for Patients with Pain-Revised (SOAPP-R), Addiction Behaviors Checklist (ABC), Current Opioid Misuse Measure (COMM) questionnaires, and Patient Global Assessment (PGA) of pain control. RESULTS Of 329 patients who received ≥ 1 hydrocodone ER dose, 284 (86 percent) reported ≥ 1 AE and 27 (8 percent) experienced ≥ 1 serious AE. Sixty-two (19 percent) patients withdrew because of AEs, and two AEs leading to death were reported. No serious AEs or AEs leading to death were considered treatment related by the investigator. There were no clinically meaningful trends in other safety assessments. SOAPP-R, ABC, and COMM scores demonstrated low risk of aberrant drug-related behavior. Good/excellent PGA responses were reported by 20 percent of patients at baseline and 75 percent at endpoint. The incidence of drug loss (11 percent) and diversion (2 percent) was low. CONCLUSIONS Hydrocodone ER demonstrated acceptable safety when administered for ≤ 12 months in patients with chronic pain. Low occurrence of aberrant drugrelated behavior may support the abuse-deterrence properties of hydrocodone ER.