Miracle-dz/UniFAR-FTUs huggingface dataset:
Deblurring and Denoising of Maps between Shapes

Shape correspondence is an important and challenging problem in geometry processing. Generalized map representations, such as functional maps, have been recently suggested as an approach for handling difficult mapping problems, such as partial matching and matching shapes with high genus, within a generic framework. While this idea was shown to be useful in various scenarios, such maps only provide low frequency information on the correspondence. In many applications, such as texture transfer and shape interpolation, a high quality pointwise map that can transport high frequency data between the shapes is required. We name this problem map deblurring and propose a robust method, based on a smoothness assumption, for its solution. Our approach is suitable for non‐isometric shapes, is robust to mesh tessellation and accurately recovers vertex‐to‐point, or precise, maps. Using the same framework we can also handle map denoising, namely improvement of given pointwise maps from various sources. We demonstrate that our approach outperforms the state‐of‐the‐art for both deblurring and denoising of maps on benchmarks of non‐isometric shapes, and show an application to high quality intrinsic symmetry computation.
Reformulation sémantique des requêtes pour la recherche d’information ad hoc sur le Web

Dans le cadre d’une solution de modification de la requete, nous nous interessons aux differentes facons d’utiliser la semantique pour mieux exprimer le besoin d’information de l’utilisateur dans un contexte Web. Nous distinguons deux types de concepts : ceux identifiables dans une ressource semantique comme une ontologie, et ceux que l’on extrait a partir d’un ensemble de documents de pseudo retour de pertinence. Nous proposons une Approche Semantique Mixte d’Expansion et de Reformulation (ASMER) qui permet de modeliser l’utilisation de ces deux types de concepts dans une requete modifiee. Cette approche considere plusieurs defis lies a la modification automatique des requetes, notamment le choix selectif des termes d’expansion, le traitement des entites nommees et la reformulation de la requete finale.Bien que dans un contexte Web la precision soit le critere d’evaluation le plus adapte, nous avons aussi pris en compte le rappel pour etudier le comportement de notre approche sous plusieurs aspects. Ce choix a suscite une autre problematique liee a l’evaluation du rappel en recherche d’information. En constatant que les mesures precedentes ne repondent pas a nos contraintes, nous avons propose la mesure MOR (Mesure Orientee Rappel), qui permet d’evaluer le rappel en tenant compte de la precision comme importante mais pas prioritaire dans un contexte dirige rappel.En incluant MOR dans notre strategie de test, nous avons evalue ASMER sur quatre collections Web issues des campagnes INEX et TREC. Nos experiences montrent qu’ASMER ameliore la performance en precision par rapport aux requetes originales et par rapport aux requetes etendues par une methode de l’etat de l’art.
Clinical Trials in Traumatic Brain Injury: Lessons for the Future

Thus far, none of the neuroprotective drugs that have been tested to reduce or prevent secondary ischemic brain damage have been shown clear benefit. We will attempt to identify factors that may be responsible for some of these failures. We also will give our thoughts on how to prevent these pitfalls in the usefulness and criteria for use of animal models for traumatic brain injury to depict human head injury are discussed. Clearly, mechanism-driven trials, in which individual pathophysiological mechanisms are targeted, are more likely to show benefit in this heterogeneous patient population. Other factors, such as the effect of brain penetration, safety and tolerability of the compound, and the interface between the pharmaceutical industry and academics are a major influence in the success of these trials. Furthermore, the way trials have been analyzes in the past may not always have been be the most appropriate to show benefits. It is clear that a multi-targeted approach is necessary to address the complicated and closely related mechanisms seen after traumatic and or ischemic brain damage.
Multiple transportable carbohydrates enhance gastric emptying and fluid delivery

This study compared the effects of ingesting water (WATER), an 8.6% glucose solution (GLU) and an 8.6% glucose+fructose solution (2:1 ratio, GLU+FRU) on gastric emptying (GE), fluid delivery, and markers of hydration status during moderate intensity exercise. Eight male subjects (age=24 ± 2 years, weight=74.5 ± 1.2 kg, VO2max=62.6 ± 2.5 mL/kg/min) performed three 120 min cycling bouts at 61% VO2max). Subjects ingested GLU, GLU+FRU (both delivering 1.5 g/min carbohydrate), or WATER throughout exercise, ingesting 2.1 L. Serial dye dilution measurements of GE were made throughout exercise and subjects ingested 5.00 g of D2O and 150 mg of 13C‐acetate at 60 min to obtain measures of fluid uptake and GE, respectively. GLU+FRU resulted in faster rates of deuterium accumulation, an earlier time to peak in the 13C enrichment of expired air and a faster rate of GE compared with GLU. GLU+FRU also attenuated the rise in heart rate that occurred in GLU and WATER and resulted in lower ratings of perceived exertion. There was a greater loss in body weight with GLU corrected for fluid intake. These data suggest that ingestion of a combined GLU+FRU solution increases GE and “fluid delivery” compared with a glucose only solution.
An Analysis of the Construction of Total Risk Management Mechanism for Enterprises' Accounts Receivable

The accounts receivable that exist in enterprises’ operational activities will slow down the turnover of capitals and cause risks of bad debts, what will block the normal circulation of capitals and restrain enterprises’ healthy and orderly development. Therefore, it is vital for Chinese enterprises to emphasize on the risk management and risk defense of accounts receivable. By theoretical analysis, this paper makes comprehensive and systematic analysis on the problems that exist in the risk management of accounts receivable and the relevant reasons. For the problems, this paper puts forward a brand-new idea of total risk management and discusses this idea in detail. So, this paper may serve as a valuable reference for Chinese enterprises’ risk management of accounts receivable.
Privacy through Biometric De-identification: Bridging the Gap Between Legal and Technological Perspectives

law. 2 Operations such as collection, transformation, storage, dissemination or re-use of personal data are understood as processing. The GDPR is the first EU instrument on data protection that has introduced a statutory definition of biometric data. Under the new regulation, facial images belong to the category of sensitive data if they are used to ‘uniquely identify’ an individual. 3 As such, they are subject to stringent data protection rules prior to their processing. One way to secure the data and ‘reduce’ their sensibility would be to ‘de-identify’ the facial images. But is it possible to separate the identifying elements of a facial image to preserve privacy while still ensuring their usability for biometric recognition? The purpose of the paper is thus to analyze the level of de-identification that is applicable to facial images to ensure data usability and data privacy at the same time.
Factors Mitigating Firm-specific Information Asymmetry and Target Price Accuracy in India

Executive Summary Over the last decade, efforts have been made to improve the quality of financial reporting and corporate governance standards prevailing in emerging markets. Even after 20 years of globalization, emerging markets continue to trade as a separate class (Bekaert & Harvey, 2014). On account of a weak regulatory environment, firm-specific information asymmetry is expected to be on the higher side as compared to developed markets. In such an environment, any factors which mitigate information asymmetry may help improve efficiency of information providers such as equity research analysts. The role of equity research analysts is to process financial information and provide estimates which may be used by investors to make informed investment decisions. This study investigates whether the factors which mitigate firm-specific information asymmetry improve analyst target price accuracy in India. We expect sophisticated financial intermediaries such as equity research analysts to produce more accurate target price forecasts for firms with higher frequency of corporate announcements, higher analyst coverage, and higher foreign institutional holdings. Past research suggests that these three factors reduce information asymmetry and this reduction could possibly help analysts produce superior results. Our results show that higher frequency of corporate announcements creates short-term noise which reduces target price accuracy at the end of one-year forecast horizon. Our findings reveal that higher analyst coverage leads to better flow of firm-specific private information and improves target price accuracy anytime during or at the end of one year. We report that higher foreign institutional holding possibly improves stock liquidity, attracting more traders, which eventually leads to better target price accuracy at the end of forecast horizon. Our key finding is that there is a reduction in firm-specific information asymmetry due to the presence of more number of analysts and higher percentage of institutional holding.
Mechanisms of Salmonella entry into host cells

Salmonella enterica is an enteric bacterial pathogen that causes a variety of food and water‐borne diseases ranging from gastroenteritis to typhoid fever. Ingested bacteria colonize the intestinal epithelium by triggering their own phagocytosis, using a sophisticated array of effector proteins that are injected into the host cell cytoplasm through a type III secretion apparatus. The synergistic action of these secreted effectors leads to a dramatic reorganization of the host actin cytoskeleton, resulting in vigorous membrane protrusion and the engulfment of attached bacteria. Analysis of these effector proteins and identification of their cellular targets has provided insight into the molecular mechanisms by which bacteria can subvert the host signalling and cytoskeletal machinery for their own purposes. This review is intended to summarize our current understanding of the tools used by Salmonella to enter host cells, with a focus on effectors that modulate the actin cytoskeleton.
Promoting the skills of knowledge translation in an online master of science course in primary health care

&NA; We present 4 key arguments: (1) knowledge translation requires tacit and explicit knowledge that must be introduced into the organization as well as simply acquired by individuals; (2) educating for knowledge translation must go beyond conveying facts and developing capability; (3) a constructivist and collaborative approach to education can address the needs of learners for knowledge translation; and (4) the online environment, if appropriately used, has many useful features for supporting constructivist and collaborative learning. We illustrate these arguments with reference to a part‐time online master of science course whose learners are mostly senior health care professionals engaged in knowledge translation.
A Combined approach for supplier selection using AHP and Fuzzy AHP in Indian Gear Manufacturing MSMEs

Industries these days across the world are required to be a part of single economy and work-culture. As a result, manufacturing industries are moving towards adding higher value activities and therefore even the requirements for suppliers in many cases undergo significant changes. By ensuring the best supplier, industries save material costs and increase their competitive advantage. Gear manufacturing companies are main suppliers for India’s leading manufacturing firms, as they outsource manufacturing of gears to Micro, Small and Medium Enterprises (MSMEs). Extant literature indicate that the Gear manufacturing companies follow traditional supply chain process and partially follows green supply chain as well as sustainability aspects. It is therefore important to understand the role, Gear manufacturing industries play in their supplier selection process. This study has explored the traditional and green manufacturing factors considered during the supplier selection in the Indian MSME Gear manufacturing sector, using tools such as AHP and FAHP. AHP is one of the best tools for deciding among the complex criteria structure at different levels. FAHP, being synthetic extension of classical AHP, considers the fuzziness of the decision makers. Results of this study indicate that, from amongst all 8 main traditional and green supply chain performance measures, cost is found to be the most important criteria for supplier selection even today in Indian industries. But, looking at the sub-factors, it is clear that the industries not only focus on purchase cost, but they also think of the disposal cost of the component, meaning they consider few aspects of green criteria as well in their decisions.
Gene Expression Change in the Müllerian Duct of the Mouse Fetus Exposed to Diethylstilbestrol In Utero

In utero exposure to diethylstilbestrol (DES) induces various abnormalities in the Müllerian duct of the mouse. In order to understand the underlying molecular mechanisms associated with DES-induced abnormalities of the Müllerian duct, gene expression was examined on Gestation Day (GD) 19 in mouse fetuses exposed to DES (67 μg/kg body weight) from GDs 10 to 18. Microarray analysis revealed that 387, 387, and 225 genes were upregulated and 177, 172, and 75 genes were downregulated by DES in the oviduct, uterus, and vagina, respectively. DES exposure in utero commonly upregulated 72 genes and downregulated 15 genes in these three organs. The present study demonstrated that organ-specific gene expression patterns in the mouse Müllerian duct were altered by in utero DES exposure. DES-induced changes in expression of genes such as Dkk2, Nkd2, and sFRP1 as well as changes in genes of the Hox, Wnt, and Eph families in the female mouse fetal reproductive tract could be the basis for various abnormalities in reproductive tracts following exposure to this estrogenic drug.
Reappraisal of the guinea-pig as an experimental host for studies of schistosomiasis mansoni

Summary The guinea-pig has been reassessed as a potential laboratory host for Schistosoma mansoni. Twenty-six per cent of an infective cercarial population survive to maturity in this rodent and there are no gross fluctuations in worm burden subsequent to pairing of male and female parasites. Five day, 4-week and 6-week-old schistosomes grown in guinea-pigs have topographical features that are identical to those exhibited by similarly aged mouse worms, but different from those exhibited by rat worms. Schistosome eggs are never detected in the faeces of infected guinea-pigs, but they can be observed in the pulmonary, hepatic and intestinal tissues. Only 55% of the eggs that can be recovered from the intestinal tissues are viable, and some of these can be hatched to release miracidia that penetrate the intermediate snail host. Cercariae are sometimes liberated from infected snails, but in insufficient numbers to permit infection of naive guinea-pigs. The schistosome cycle cannot, therefore, be completed in this host. Collaterals are sometimes observed in the vasculature serving the rectum and kidneys of infected guinea-pigs and the fact that schistosome eggs are deposited in the lungs of these animals indicates that portal systemic anastomosis is a feature of the model. Pathology associated with cercarial invasion or egg deposition is not dissimilar to that described for other laboratory animals infected with S. mansoni, except that basophils participate in the inflammatory response observed in the skin and intestine.
ALIX: une méthode de modélisationdes flux d'un système de production

Ce papier presente un formalisme graphique de modelisation en entreprise destine a la simulation des flux. Parmi les contextes statique, decisionnel et dynamique de la modelisation, seul le contexte dynamique est aborde dans cet article ; les deux autres aspects etant en phase de developpement. Ce formalisme est inspire de methodes de reference telles que SADT et UML. Il est destine a s'integrer dans une plate-forme complete d'analyse et d'optimisation. Celle-ci constitue un projet en cours de developpement au sein de l'equipe de recherche du CREGI. Cette plate-forme d'analyse a pour objectifs la simulation et l'optimisation, axes de recherches privilegies et depuis longtemps utilises au CREGI dans le cadre de bon nombre de projets industriels.
Medicaid and Education: The Impact of Medicaid Coverage on Children's Educational Trajectory

This paper examines the impact of Medicaid and the State Children’s Health Insurance Program (CHIP) on children’s educational progress, namely whether they are on track with their expected educational trajectory. It also examines cross-state variation in Medicaid policies and whether these different policies lead to different effects on the educational variable. With individual-level data from the Current Population Survey from years 1995 through 2006, along with information regarding each state’s Medicaid policies, I seek to test the hypotheses that Medicaid/CHIP coverage will improve the likelihood of an individual being on track with his/her education and that states with qualitatively “better” Medicaid policies will see stronger positive effects on that educational measure. Using an ordinary least squares regression model composed of Medicaid/CHIP indicators, demographic characteristics, state dummies, and state*Medicaid interaction terms, I find that, counter to the past research underlying these hypotheses, there is evidence that being covered by Medicaid or CHIP has a small, but statistically significant, negative impact on whether a child is on track with his/her education in a given year. Furthermore, there is no evidence of a discernible pattern linking qualitatively “better” state Medicaid programs to higher values for the dependent variable. Further evidence suggests, however, that there may be a cumulative positive effect of Medicaid/CHIP coverage; that is, longer exposure to available public health insurance programs is shown to have a positive impact on whether an individual is on track with his/her education. Although the data did not support the original hypotheses, this analysis does provide support for the idea that there is some relationship between Medicaid/CHIP coverage and educational variable, and therefore points to the importance of future research in this area. Acknowledgements I would like to thank the faculty of the Oberlin Department of Economics for all of their guidance throughout my whole research process. I would especially like to thank Prof. Craig and Prof. Kasper for providing me with invaluable insight. Without them, this paper would not have been possible. Thank you.
Transferring Syntactic Relations of Subject-Verb-Object Pattern in Chinese-to-Korean SMT

Since most Korean postpositions signal grammatical functions such as syntactic relations, generation of incorrect Korean post-positions results in producing ungrammatical outputs in machine translations targeting Korean. Chinese and Korean belong to morphosyntactically divergent language pairs, and usually Korean postpositions do not have their counterparts in Chinese. In this paper, we propose a preprocessing method for a statistical MT system that generates more adequate Korean postpositions. We transfer syntactic relations of subject-verb-object patterns in Chinese sentences and enrich them with transferred syntactic relations in order to reduce the morpho-syntactic differences. The effectiveness of our proposed method is measured with lexical units of various granularities. Human evaluation also suggest improvements over previous methods, which are consistent with the result of the automatic evaluation.
Minimum Entropy Active Fault Tolerant Control of the Non-Gaussian Stochastic Distribution System Subjected to Mean Constraint

Stochastic distribution control (SDC) systems are a group of systems where the outputs considered is the measured probability density function (PDF) of the system output whilst subjected to a normal crisp input. The purpose of the active fault tolerant control of such systems is to use the fault estimation information and other measured information to make the output PDF still track the given distribution when the objective PDF is known. However, if the target PDF is unavailable, the PDF tracking operation will be impossible. Minimum entropy control of the system output can be considered as an alternative strategy. The mean represents the center location of the stochastic variable, and it is reasonable that the minimum entropy fault tolerant controller can be designed subjected to mean constraint. In this paper, using the rational square-root B-spline model for the shape control of the system output probability density function (PDF), a nonlinear adaptive observer based fault diagnosis algorithm is proposed to diagnose the fault. Through the controller reconfiguration, the system entropy subjected to mean restriction can still be minimized when fault occurs. An illustrative example is utilized to demonstrate the use of the minimum entropy fault tolerant control algorithms.
Proposed allosteric inhibitors bind to the ATP site of CK2α

CK2α is a ubiquitous, well-studied protein kinase that is a target for small molecule inhibition, for treatment of cancers. While many different classes of ATP-competitive inhibitors have been described for CK2α, they tend to suffer from significant off-target activity and new approaches are needed. A series of inhibitors of CK2α has recently been described as allosteric, acting at a previously unidentified binding site. Given the similarity of these inhibitors to known ATP-competitive inhibitors, we have investigated these further. In our thorough structural and biophysical analyses, we have found no evidence that these inhibitors bind to the proposed allosteric site. Rather, we report crystal structures, competitive ITC and NMR, HDX mass spectrometry and chemoinformatic analyses that all point to these compounds binding in the ATP pocket. Our crystal structures however do show that the proposed allosteric site can bind ligands, just not those in the previously described series. Comparison of our results and experimental details with the data presented in the original report suggest several reasons for the disparity in our conclusions, the primary reason being non-specific inhibition by aggregation.