Miracle-dz/UniFAR-FTUs huggingface dataset:
Molecular cloning of the maize gene crp1 reveals similarity between regulators of mitochondrial and chloroplast gene expression

The maize nuclear gene crp1 is required for the translation of the chloroplast petA and petD mRNAs and for the processing of the petD mRNA from a polycistronic precursor. In order to understand the biochemical role of the crp1 gene product and the interconnections between chloroplast translation and RNA metabolism, the crp1 gene and cDNA were cloned. The predicted crp1 gene product (CRP1) is related to nuclear genes in fungi that play an analogous role in mitochondrial gene expression, suggesting an underlying mechanistic similarity. Analysis of double mutants that lack both chloroplast ribosomes and crp1 function indicated that CRP1 activates a site‐specific endoribonuclease independently of any role it plays in translation. Antibodies prepared to recombinant CRP1 were used to demonstrate that CRP1 is localized to the chloroplast stroma and that it is a component of a multisubunit complex. The CRP1 complex is not associated detectably with either chloroplast membranes or chloroplast ribosomes. Models for CRP1 function and its relationship to other activators of organellar translation are discussed.
ВЫБОР ЛИЧНЫХ МЕСТОИМЕНИЙ ТРЕТЬЕГО ЛИЦА В ДИСКУРСЕ CHOICE OF THIRD-PERSON PRONOUNS IN DISCOURSE 1

Выбор референциальных выражений в дискурсе в высокой степени зависим от контекстных характеристик референта. В настоящей работе рассматриваются условия употребления прототипических (например, актантных) и периферийных (например, посессивных) местоимений. Для анализа использовались два немецких корпуса, аннотированных по референции: PCC (Stede 2004) и NEGRA (Skut et al. 1997). Результаты подтверждают гипотезу о том, что различные типы местоимений по-разному чувствительны к параметру расстояния. Также на основании анализа влияния факторов одушевленности, синтаксического параллелизма, дискурсивной выделенности, позиции в предложении и дискурсивной структуры, было обнаружено влияние нескольких компенсирующих механизмов: референциального и риторического расстояния; одушевленности и расстояния; преимущество первого упоминания и позиции в предложении, топикальной устойчивости и расстояния.
A 4-GHz low-power TDC-based all digital PLL having 9.6mW and 1.2ps rms jitter

This paper presents a 4-GHz ADPLL with low-power TDC using two low-rate retimed reference clocks (pCKR, nCKR) to measure the fractional phase error between the reference clock edge and DCO clock edge. The application of the retimed reference clocks enables TDC to avoid metastability of its sampling register as well as alleviate large dynamic power of its delay inverter chain. A mode-decision block is also proposed to generate suitable control signals for accomplishing seamless movement of DCO operation mode. The proposed ADPLL achieves − 95 dBc/Hz in-band phase noise and 1.2ps rms jitter, consuming 9.6mW.
Licensed under Creative Commons Attribution Cc by Pdoc in Location – Based Social Networks

Now a days the usage of social network such as facebook , flicker increases day by day. Most of the social networking sites support Location Based Services (LBS). Location based social network used to identify the friend's location and the current location details of the user. The Increasing availability of the smartphone makes the location based services more flexible. Most of the location based social networks do not have an explicit community structure. All the social network users belongs to at least any one of the community depending upon their behavior and interest. Sometime the community structure may overlap. In this paper, by tracing the user locations use a multimode multi-attribute edge centric co-clustering framework to detect the overlapping community . The proposed framework uses both inter-mode and intra-mode features. By evaluating the collected dataset we can analyze the efficiency of our approach.
Life Patterns

In this thesis I develop and evaluate computational methods for extracting life’s patterns from wearable sensor data. Life patterns are the reoccurring events in daily behavior, such as those induced by the regular cycle of night and day, weekdays and weekends, work and play, eating and sleeping. My hypothesis is that since a “raw, low-level” wearable sensor stream is intimately connected to the individual’s life, it provides the means to directly match similar events, statistically model habitual behavior and highlight hidden structures in a corpus of recorded memories. I approach the problem of computationally modeling daily human experience as a task of statistical data mining similar to the earlier efforts of speech researchers searching for the building block that were believed to make up speech. First we find the atomic immutable events that mark the succession of our daily activities. These are like the “phonemes” of our lives, but don’t necessarily take on their finite and discrete nature. Since our activities and behaviors operate at multiple time-scales from seconds to weeks, we look at how these events combine into sequences, and then sequences of sequences, and so on. These are the words, sentences and grammars of an individual’s daily experience. I have collected 100 days of wearable sensor data from an individual’s life. I show through quantitative experiments that clustering, classification, and prediction is feasible on a data set of this nature. I give methods and results for determining the similarity between memories recorded at different moments in time, which allow me to associate almost every moment of an individual’s life to another similar moment. I present models that accurately and automatically classify the sensor data into location and activity. Finally, I show how to use the redundancies in an individual’s life to predict his actions from his past behavior.
Video Quality Experts Group: current results and future directions

The Video Quality Experts Group (VQEG) was formed in October 1997 to address video quality issues. The group is composed of experts from various backgrounds and affiliations, including participants from several internationally recognized organizations working int he field of video quality assessment. The first task undertaken by VQEG was to provide a validation of objective video quality measurement methods leading to recommendations in both the telecommunications and radiocommunication sectors of the International Telecommunications Union. To this end, VQEG designed and executed a test program to compare subjective video quality evaluations to the predictions of a number of proposed objective measurement methods for video quality in the bit rate range of 768 kb/s to 50 Mb/s. The results of this test show that there is no objective measurement system that is currently able to replace subjective testing. Depending on the metric used for evaluation, the performance of eight or nine models was found to be statistically equivalent, leading to the conclusion that no single model outperforms the others in all cases. The greatest achievement of this first validation effort is the unique data set assembled to help future development of objective models.
Dynamic load balanced routing in IP networks

In this paper, we address the dynamic load balanced routing problem in IP networks. In current IP networks, shortest paths are selected for routing based on static link weight metrics. Due to the lack of stringent synchronization among routers, dynamically changing link weight would generate transient loops. How to perform dynamic load balanced routing without generating traffic loops become a challenging task. In this work, we propose two approaches, Local Traffic Rerouting (LTR) and Global Traffic Rerouting (GTR), to resolve the problem. Both approaches use a set of static link weight metrics. Each router obtains the metrics through standard link state routing protocol. Based on the link metrics, in each router, a directed acyclic graph (DAG) for each destination node is derived. Taking the advantage of the property that there is no loop in a DAG, each router can make its decision to dynamically select next hop node for routing. The major difference between LTR and GTR is that the former uses only local information while the latter uses global information on routing decision. In LTR, each router monitors its links to obtain the bandwidth utilization. In GTR, the local link utilization information is broadcast to the whole network through routing protocol so each node in the network knows the state of the whole network. We have conducted simulations and experiments to make performance comparisons among various routing approaches. The results indicate that LTR and GTR significantly outperform conventional static routing on minimizing link utilization of the most congested link. They also have performance close to a per flow based centralized controlled routing that is served for a lower bound for performance evaluations.
A Broadcast Vehicle to Vehicle Communication System in Railway Environments

statistics in railway transportation systems show that the number of accidents is still too high, despite of huge investments in infrastructure-based safety systems. We show that a infrastructure-less cross-layer train-to-train commu- nication system exploiting all characteristics of a pervasive computing system, like direct communication in mobile ad- hoc networks (MANETs), exchange of location and other relevant context information provided by multiple sensors in the trains, can reveal hazardous situations. While mar- itime and air transport are already benefiting from collision avoidance applications based on infrastructure-less commu- nications and similar applications will be available for road users built on top of car-to-car communications soon, an equivalent for rail transport systems is not existing yet. In order to design such a system, a six phase work approach is conducted: Preliminary analysis and selection of an ad- equate frequency band, characterization of the propagation channel, MAC layer design, physical layer and finally veri- fication of the system. During this process, context infor- mation provided by navigation systems and other sensors, e.g. position, time and speed are utilized to improve the communication.
A Survey of Semantic based Solutions to Web Mining

An effective retrieval of the most relevant documents from the Web is difficult due to the large amount of information in all types of formats. Researches have been conducted on ways to improve the efficiency of Information Retrieval (IR) systems. To arrive to suitable solutions in IR systems, machines need additional semantic information that helps in understanding Web documents. This is made true by an intelligent web called the Semantic Web, which offers users the ability to work on shared meaningful knowledge representations on the web. Semantic Web makes the Web content meaningful to computers and it intends to support machine-processing capabilities. Using Semantic Web is a way to increase the precision of IR systems. This paper focuses on the various Semantic-based approaches in Web mining research.
Multi-track pension system and life satisfaction of urban elders in China

Abstract There exist three pension systems for urban older residents in China: the pension for government and public institutions (PGPI), the worker's old-age insurance for enterprise employees (WOI) and the urban residents’ social pension insurance (URSPI). This study examines how this multi-track pension system relates to older urbanites’ life satisfaction. The ordered logistic regression model was fitted to analyse the urban sample of the China Longitudinal Ageing Social Survey (60+ years), a nationwide representative survey collected in 2014. The mediation analyses were further adopted to investigate the potential formative mechanisms. A significantly higher level of life satisfaction was detected for those who receive PGPI benefits relative to those who have access to URSPI and WOI, but no significant difference is detected between URSPI and WOI. Further analyses suggest that the advantage of PGPI in terms of life satisfaction is mediated not through monetary resources, but through the dispositional factor of perceived self-value for the society. This study suggests that different institutional configurations of the pension system stratify older urbanites’ subjective wellbeing by virtue of factors that are associated with people's capabilities of acting and functioning.
“New” Antigenic Targets and Methodological Approaches for Refining Laboratory Diagnosis of Antiphospholipid Syndrome

Antiphospholipid antibodies (aPLs) are a heterogeneous group of antibodies directed against phospholipids or protein/phospholipid complexes. Currently, aPLs are assessed using either “solid-phase” assays that identify anticardiolipin antibodies and anti-β2-glycoprotein I antibodies or “liquid-phase” assay that identifies lupus anticoagulant. However, in the last few years, “new” antigenic targets and methodological approaches have been employed for refining laboratory diagnosis of antiphospholipid syndrome (APS). In this review the potential diagnostic value of antibodies to domains of β2-GPI, prothrombin/phosphatidylserine, vimentin/cardiolipin, protein S, protein C, annexin A2, annexin A5, and phospholipid antigens is discussed. Moreover, new technical approaches, including chemiluminescence, multiline dot assay, and thin layer chromatography (TLC) immunostaining, which utilize different supports for detection of aPL, have been developed. A special focus has been dedicated on “seronegative” APS, that is, those patients with a clinical profile suggestive of APS (thromboses, recurrent miscarriages, or foetal loss), who are persistently negative for the routinely used aPL. Recent findings suggest that, in sera from patients with SN-APS, antibodies may be detected using “new” antigenic targets (mainly vimentin/cardiolipin) or methodological approaches different from traditional techniques (TLC immunostaining). Thus, APS represents a mosaic, in which antibodies against different antigenic targets may be detected thanks to the continuously evolving new technologies.
Calibration of car-following models with single- and multi-step approaches

Microscopic traffic simulation models are applied in the analysis of transportation systems for years. Nevertheless, calibration (and validation) of microscopic sub-models such as car-following and gap-acceptance models is still a recent matter. The objective of the calibration is to adapt the simulation output to empirical data by adjusting the model's parameters. However, simulation results may vary from the underlying real-world data, despite the calibration. To analyze these deviations the present paper compares two different approaches of calibration using data from a single-lane car-following experiment on a Japanese test track. It is demonstrated that the results of the two methods differ significantly. A recommendation for the more appropriate method to use is given.
Blood Donation and Colorectal Cancer Incidence and Mortality in Men

Background Although blood donations may reduce body iron stores, to date, prospective data on frequent blood donation and colorectal cancer risk are limited. Methodology/Principal Findings We tested whether frequent blood donation is associated with a lower risk of colorectal cancer in the Health Professionals Follow-up Study. We prospectively followed 35,121men who provide the information on lifetime number of blood donations in 1992 through 2008. Serum ferritin levels were measured in a random sample of 305 men. Cox proportional hazard regression models were used to calculate the multivariable relative risks (RRs, 95%CIs) after adjusting for age and other established colorectal cancer risk factors. We documented 684 incident colorectal cancer cases and 224 deaths from colorectal cancer. The mean serum ferritin levels varied from 178 µg/L for men who did not donate blood to 98 µg/L for men who had at least 30 donations. Age-adjusted results for both incidence and mortality were essentially the same as the multivariable-adjusted results. Comparing with non-donors, the multivariable RRs (95%CIs) for colorectal cancer incidence were 0.92 (0.77, 1.11) for 1–5 donation, 0.85 (0.64, 1.11) for 6–9 donations, 0.96 (0.73, 1.26) for 10–19 donations, 0.91 (0.63, 1.32) for 20–29 donations, and 0.97 (0.68, 1.38) for at least 30 donations (P trend = 0.92). The multivariable RRs for colorectal cancer mortality were 0.99 (0.72, 1.36) for 1–5 donation, 0.93 (0.57, 1.51) for 6–9 donations, 0.85 (0.50, 1.42) for 10–19 donations, and 1.14 (0.72, 1.83) for at least 20 donations (P trend = 0.82). The results did not vary by cancer sub-sites, intake levels of total iron, heme iron, or family history of colorectal cancer. Conclusions/Significance Frequent blood donations were not associated with colorectal cancer incidence and mortality in men. Our results do not support an important role of body iron stores in colorectal carcinogenesis.
Robotic Cell Injection System With Position and Force Control: Toward Automatic Batch Biomanipulation

Biological cell injection is laborious work that requires lengthy training and suffers from a low success rate. In this paper, a robotic cell-injection system for automatic injection of batch-suspended cells is proposed. To facilitate the process, these suspended cells are held and fixed to a cell array by a specially designed cell-holding device, and injected one by one through an ldquoout-of-planerdquo cell-injection process. A micropipette equipped with a polyvinylidene fluoride microforce sensor to measure real-time injection force is integrated in the proposed system. Through calibration, an empirical relationship between the cell-injection force and the desired injector pipette trajectory is obtained in advance. Then, after decoupling the out-of-plane cell injection into a position control in the X - Y horizontal plane and an impedance control in the Z -axis, a position and force control algorithm is developed to control the injection pipette. The depth motion of the injector pipette, which cannot be observed by microscope, is indirectly controlled via the impedance control, and the desired force is determined from the online X - Y position control and cell calibration results. Finally, experimental results demonstrate the effectiveness of the proposed approach.
A convenient device for replacing rounded zeros in compositional data : aln model

Formally, a composition is a vector x = [x1, . , xD] such that xj > 0, j = 1, . , D, subject to the constraint x1 + . +xD = 1. The sample space of compositions is the unit simplex SD. Its peculiarities prevent us from applying the standard multivariate statistical techniques designed for real spaces. Log-ratio methodology (Aitchison, 1986) provides the one to one correspondences between the simplex and the real space, opening up the whole of unconstrained real space multivariate data analysis. The results can then be translated back into the compositions of the simplex. Sometimes in practice some parts take rounded zero values or trace zeros, making it impossible to use the log-ratio methodology. From a nonparametric point of view, the multiplicative replacement (MR) method (Mart́ın-Fernández et al., 2003) replaces the zeros by a small number provided by the analyst. In this work, a computationally feasible parametric method based on a modification of the EM-algorithm is proposed. Its performance is analyzed by Monte Carlo simulation.
Performance Analysis of A Beyond 3G Mobile Communication System in the Presence of Co-channel Interference

: - This paper presents a new model for systems beyond 3G of cellular communication techniques. The proposed scheme includes several new techniques: multiple-input multiple-output (MIMO), orthogonal frequency division multiplexing (OFDM), and smart antennas (beamforming). The performance analysis was done in an interference-rich environment, and closed form expression for SINR was also determined. The results proved the effectiveness of the proposed system, particularly, in the presence of co-channel interference (CCI).
A simple DTC-SVM method for matrix converter drives using a deadbeat scheme

In this paper, a simple direct torque control (DTC) method for sensorless matrix converter drives is proposed, which is characterized by a simple structure, minimal torque ripple and unity input power factor. Also a good sensorless speed-control performance in the low speed operation is obtained, while maintaining constant switching frequency and fast torque dynamics. It is possible to combine the advantages of matrix converters with the advantages of the DTC strategy using space vector modulation a deadbeat algorithm in the stator flux reference frame. Experimental results are shown to illustrate the feasibility of the proposed strategy
A robust semi-supervised classification method for transfer learning

The transfer learning problem of designing good classifiers with a high generalization ability by using labeled samples whose distribution is different from that of test samples is an important and challenging research issue in the fields of machine learning and data mining. This paper focuses on designing a semi-supervised classifier trained by using unlabeled samples drawn by the same distribution as test samples, and presents a semi-supervised classification method to deal with the transfer learning problem, based on a hybrid discriminative and generative model. Although JESS-CM is one of the most successful semi-supervised classifier design frameworks and has achieved the best published results in NLP tasks, it has an overfitting problem in transfer learning settings that we consider in this paper. We expect the overfitting problem to be mitigated with the proposed method, which utilizes both labeled and unlabeled samples for the discriminative training of classifiers. We also present a refined objective that formalizes the training algorithm and classifier form. Our experimental results for text classification using three typical benchmark test collections confirmed that the proposed method outperformed the JESS-CM framework with most transfer learning settings.
Mutational screening of SCN 5 A linked disorders in Polish patients and their family members

Mutations in SCN5A lead to a broad spectrum of phenotypes, including the Long QT syndrome, Brugada syndrome, Idiopathic ventricular fibrillation (IVF), Sudden infant death syndrome (SIDS) (probably regarded as a form of LQT3), Sudden unexplained nocturnal death syndrome (SUNDS) and isolated progressive cardiac conduction defect (PCCD) (Lev-Lenegre disease). Brugada Syndrome (BS) is a form of idiopathic ventricular fibrillation characterized by the right bundle-branch block pattern and ST elevation (STE) in the right precordial leads of the ECG. Mutations of the cardiac sodium channel SCN5A cause the disorder, and an implantable cardioverter-defibrillator is often recommended for affected individuals. In this study sequences of the coding region of the SCN5A gene were analysed in patients with the LQT3, Brugada Syndrome and other arrythmogenic disorders. Different mSSCP patterns are described with no disease-related SSCP conformers in any sample. Direct sequencing of the SCN5A gene confirmed the absence of mutations. This suggests that the analysed region of the SCN5A gene is not commonly involved in the pathogenesis of the Brugada Syndrome and associated disorders.