Miracle-dz/UniFAR-FTUs huggingface dataset:
Cutaneous Infection with Mycobacterium abscessus in a Child

Abstract: Nontuberculous mycobacteria can cause cutaneous infections in both children and adults. Localized nontuberculous mycobacterial infections of the skin have been reported in children following injections or surgical procedures. We report a child who developed a cutaneous nontuberculous mycobacterial infection after exposure of a skin wound to pond water. Cutaneous infection with the rapidly growing mycobacteria Mycobacterium abscessus was demonstrated by clinical and histologic evaluation on the lower leg of an otherwise healthy 12‐year‐old Caucasian boy. We describe this as an instance of an unusual acquisition of cutaneous M. abscessus infection in a child.
Space Efficient Cryptographic Protocol Using Recursive Bitwise & Pairs Of Bits Of Operation (RBPBO)

The technique considers a message as binary string on which a “Efficient Cryptographic Protocol using Recursive Bitwise & pairs of Bits of operation (RBPBO)” is performed. A block of n bits is taken as an input stream, where n varies from 4 to 256, from a continuous stream of bits and the technique operates on it to generate the intermediate encrypted stream. This technique directly involves all the bits of blocks in a boolean operation and a session key. The same operation is performed repeatedly for different block sizes as per the specification of a session key to generate the final encrypted stream. It is a kind of block cipher and symmetric in nature hence, decoding is done following the same procedure. A comparison of the proposed technique with existing and industrially accepted RSA and TDES has also been done in terms of frequency distribution and non homogeneity of source and encrypted files.
Stance selection for humanoid grasping tasks by inverse reachability maps

In grasping tasks carried out with humanoids, knowledge about the robot's reachable workspace is important. Without this knowledge, it might be necessary to repeatedly adapt the stance location and call an inverse kinematics solver before a valid robot configuration to reach a given grasping pose can be found. In this paper, we present an approach to select an optimal stance location in SE(2) for a humanoid robot's feet relative to a desired grasp pose. We use a precomputed representation of the robot's reachable workspace that stores quality information in addition to spatial data. By inverting this representation we obtain a so-called inverse reachability map (IRM) containing a collection of potential stance poses for the robot. The generated IRM can subsequently be used to select a statically stable, collision-free stance configuration to reach a given grasping target. We evaluated our approach with a Nao humanoid in simulation and in experiments with the real robot. As the experiments show, using our approach optimal stance poses can easily be obtained. Furthermore, the IRM leads to a substantially increased success rate of reaching grasping poses compared to other meaningful foot placements within the vicinity of the desired grasp.
Prediction of Tumor Recurrence in Patients with Non-Gastric Gastrointestinal Stromal Tumors Following Resection according to the Modified National Institutes of Health Criteria

Background/Aims Few studies have investigated the prognosis of non-gastric gastrointestinal stromal tumors (GISTs) under the modified National Institutes of Health (NIH) consensus criteria in Korea. This study aims to clarify the clinical usefulness of the modified NIH criteria for risk stratification. Methods From January 2000 through October 2012, 88 patients who underwent curative resection for primary GISTs were included in this study. The enrolled patients were stratified to predict recurrence by the original NIH criteria and modified NIH criteria. Results In all, 88 patients had non-gastric GISTs, including 82 and 6 patients with GISTs of the small intestine and colorectum, respectively. The mean age was 57.3±13.0 years, and the median follow-up duration was 3.40 years (range, 0.02-12.76 years). All patients who were placed in the intermediate-risk category according to the original NIH criteria were reclassified into the high-risk category according to the modified NIH criteria. Therefore, the proportion of cases in the intermediate-risk category declined to 0.0% from 25.0% (22/88), and the proportion of cases in the high-risk category increased to 43.2% (38/88) from 18.2% (16/88) under the modified NIH criteria. Among the 22 reclassified patients, 6 (27.3%) suffered a recurrence during the observational period, and the recurrence rate of high-risk category patients was 36.8% (14/38). Conclusions Patients in the high-risk category according to the modified NIH criteria had a high GIST recurrence rate. Therefore, the modified NIH criteria are clinically useful in selecting patients who need imatinib adjuvant chemotherapy after curative surgical resection.
SELECTIVE NEIGHBOURING WAVELET COEFFICIENTS APPROACH FOR IMAGE DENOISING

SELECTIVE NEIGHBOURING WAVELET COEFFICIENTS APPROACH FOR IMAGE DENOISING B. Chinna Rao1, M. Madhavi Latha2 1 Department of ECE, RK College of Engineering, Vijayawada, A.P., India, E-mail: Chinnarao_Ece@Yahoo.co.in. 2 Department of ECE, Jntu College of Engineering, Hyderabad, A.P., India, E-mail: Mlmakkena@Yahoo.com. The denoising of a natural image corrupted by Gaussian noise is a classical problem in signal or image processing. G.Y. Chen, Donoho and his coworkers at Stanford pioneered a wavelet denoising scheme by thresholding the wavelet coefficients arising from the standard discrete wavelet transform. This work has been widely used in science and engineering applications. However, this denoising scheme tends to kill too many wavelet coefficients that might contain useful image information. In this paper, we propose one selective approach wavelet image thresholding scheme by incorporating neighbouring coefficients, namely Selected NeighShrink. This approach is valid because a large wavelet coefficient will probably have large wavelet coefficients as its neighbours. We selected the neighbours based on the directions. Here we selected widow size 3 × 3 to get better results.
Quadrotor Control Design under Time and State Constraints: Implicit Lyapunov Function Approach

The problem of a state feedback design for control of a quadrotor system under state and time constraints is studied. Convex embedding approach and Implicit Lyapunov function are employed to design a finite-time controller. The feedback gain is solved by a system of LMIs(Linear Matrix Inequalities). Theoretical results are supported with numerical simulation.
RULED SURFACES WITH NON-TRIVIAL SURJECTIVE ENDOMORPHISMS

Let X be a non-singular ruled surface over an algebraically closed field of characteristic zero. There is a non-trivial surjective endomorphism f :X →X if and only if X is (1) a toric surface, (2) a P1-bundle over an elliptic curve, or (3) the direct product of P1 and a non-singular curve up to finite etale coverings.
Domain name based visualization of Web histories in a zoomable user interface

Users of hypertext systems like the World Wide Web (WWW) often find themselves following hypertext links deeper and deeper, only to find themselves "lost" and unable to find their way back to the previously visited pages. We have implemented a Web browser companion called Domain Tree Browser (DTB) that builds a tree structured visual navigation history while browsing the Web. The Domain Tree Browser organizes the URLs visited based on the domain name of each URL and shows thumbnails of each page in a zoomable window.
Physical and Sensory Analysis of High Fiber Bread Incorporated with Jackfruit Rind Flour

The main objectives of this study were to develop jackfruit-based high fiber bread by utilizing jackfruit rind flour in bread formulation, and to characterize physical properties of produced high fibre bread. Jack fruit rind pieces were undergone few soaking and washing steps prior to get dried and milled. Obtained Jackfruit rind flour (JRF) was incorporated into wheat flour (WF) in three different ratio (5, 10 and 15%) to produce partially substituted wheat flour (WF) with JRF. Allbread samples including bread sample based on WF (BC (as control)), bread based on WF substituted with 5% JRF (B5JRF), bread based on WF substituted with 10% JRF (B10JRF) and bread based on WF substituted with 15% JRF (B15JRF) were undergone proximate and physical analysis. The incorporation of JRFcaused significant influence on bread volume and texture attributes. Increasing the level of JRF incorporated into WF caused an increase in hardness and darkness of bread samples, and decrease in their volume compared to the control. Bread samples substituted with 5% JRF had the highest mean scores of overall acceptance.
The Interactive Design Approach for Aerodynamic Shape Design Optimisation of the Aegis UAV

In this work, an interactive optimisation framework—a combination of a low fidelity flow solver, Athena Vortex Lattice (AVL), and an interactive Multi-Objective Particle Swarm Optimisation (MOPSO)—is proposed for aerodynamic shape design optimisation of any aerial vehicle platform. This paper demonstrates the benefits of interactive optimisation—reduction of computational time with high optimality levels. Progress towards the most preferred solutions is made by having the Decision Maker (DM) periodically provide preference information once the MOPSO iterations are underway. By involving the DM within the optimisation process, the search is directed to the region of interest, which accelerates the process. The flexibility and efficiency of undertaking optimisation interactively have been demonstrated by comparing the interactive results with the non-interactive results of an optimum design case obtained using Multi-Objective Tabu Search (MOTS) for the Aegis UAV. The obtained results show the superiority of using an interactive approach for the aerodynamic shape design, compared to posteriori approaches. By carrying out the optimisation using interactive MOPSO it was shown to be possible to obtain similar results to non-interactive MOTS with only half the evaluations. Moreover, much of the usual complexity of post-data-analysis with posteriori approaches is avoided, since the DM is involved in the search process.
Genetic polymorphisms in TNIP1 increase the risk of gastric carcinoma

The distribution and levels of TNIP1 in malignant and normal gastric mucosa are different, but it is not known whether TNIP1 polymorphisms are related to gastric carcinogenesis. To assess the association between four TNIP1 SNPs (rs3792792, rs4958881, rs7708392, rs10036748) and carcinogenesis, we used Sequenom Mass-ARRAY technology to determine the genotypes of 302 gastric carcinoma patients and 300 healthy controls in a Northwest Chinese Han population. These data were then compared using the Chi-square test/Fisher's exact test, genetic model analysis, and haplotype analysis. Odds ratios (OR) and 95% confidence intervals (CI) were used to evaluate the correlation. We observed that patients with the “G” allele of rs7708392 and the “C” allele of rs10036748 showed an increased risk of gastric carcinoma (OR= 1.335, 95%CI: 1.021-1.745, P= 0.035; OR= 1.358, 95%CI: 1.039-1.774, P= 0.025, respectively). Conversely, the haplotype “CT” of TNIP1 (rs7708392-rs10036748) may act as a genetic protective factor for gastric carcinoma (adjusted OR= 0.731, 95%CI: 0.552-0.970, P= 0.030). Our results are the first to suggest that genetic variation in TNIP1 gene is associated with gastric carcinoma, though, this finding must be confirmed in other populations with larger sample size.
Recovery in Distributed Systems from Transient and Permanent Faults

The recovery mechanism from transient fault in distributed systems has been intensively studied in the past, but to our best knowledge, none of these studies has been devoted to cope together with transient and permanent hard faults. Our study devoted to recovery processes in a distributed environment in case of hard faults like transient or permanent. The recovery mechanism we presented can be based on one of the six proposed strategies involving checkpointing and message logging between distributed application processes. This exhaustive number is system-dependant. The strategies have been examined with respect to propagation recovery through processes in order to prevent the fastidious well known domino effect problem. The considered framework was a distributed system composed of a set of autonomous nodes running each one a local system; and some of them were predisposed to replace failing ones in case of permanent fault. Our main contribution was to enable a distributed application to meet its requirements of terminating its mission in spite of node crash. Preliminary experimental results of a fault tolerant mechanism based upon one of the proposed strategies demonstrated that our proposals seem to be conclusive.
Effect of idiotype-specific suppressor T cells on primary and secondary responses

Previous reports have shown that suppression of idiotype can be adoptively transferred by T cells, or by rosettes containing T cells with anti-idiotypic receptors, from an idiotypically suppressed, syngeneic mouse. The present data indicate that secondary B cells are highly resistant to such suppression. Priming recipients to the relevant hapten, p-azophenylarsonate, 6 days or 4 mo before the adoptive transfer prevented suppression. This was independent of the carrier used for the hapten group during priming or subsequent immunization, suggesting that resistance to suppression is attributable to secondary cells with specificity for the hapten. The effect of suppressor T cells could also be overcome by mixing them with specifically purified B cells having receptors for the hapten group before the adoptive transfer. Adoptive transfer of the suppressed state by specifically purified B cells from suppressed, hyperimmunized animals confirmed our previous finding that the suppression of idiotype can also be caused by B cells lacking idiotypic receptors, evidently through a mechanism involving clonal dominance. Possible mechanisms of idiotypic suppression by T cells are discussed.
Opportunities and Challenges for Incorporating Runtime Ethical Constraints into a Learning Agent

As the capabilities and performance of learning agents continue to improve, we must ensure that these agents behave ethically. Existing approaches introduce a separate component to filter agent behavior. We propose an alternative framework, where the processing uses fixed knowledge embedded in the agent. In this paper, we describe this approach and our implementation, contrasting it with using a separate component. The integration with the agent provides additional capabilities beyond previous approaches so that it can more efficiently evaluate actions and perform minor re-planning when all actions violate its constraints. We demonstrate an implementation of our approach in the cognitive architecture Soar for a simple agent and show that it effectively prevents the agent from executing actions that would violate its constraints. We also discuss challenges that arise from our implementation.
Evaluating Text Quality: Judging Output Texts Without a Clear Source

We consider how far two attributes of text quality commonly used in MT evaluation -- intelligibility and fidelity -- apply within NLG. While the former appears to transfer directly, the latter needs to be completely re-interpreted. We make a crucial distinction between the needs of symbolic authors and those of end-readers. We describe a form of textual feedback, based on a controlled language used for specifying software requirements that appears well suited to authors' needs, and an approach for incrementally improving the fidelity of this feedback text to the content model.
A new model selection procedure for finite mixture regression models

Abstract In this article, we propose a new penalized-likelihood method to conduct model selection for finite mixture of regression models. The penalties are imposed on mixing proportions and regression coefficients, and hence order selection of the mixture and the variable selection in each component can be simultaneously conducted. The consistency of order selection and the consistency of variable selection are investigated. A modified EM algorithm is proposed to maximize the penalized log-likelihood function. Numerical simulations are conducted to demonstrate the finite sample performance of the estimation procedure. The proposed methodology is further illustrated via real data analysis.
Word Disambiguation in Shahmukhi to Gurmukhi Transliteration

To write Punjabi language, Punjabi speakers use two different scripts, Perso-Arabic (referred as Shahmukhi) and Gurmukhi. Shahmukhi is used by the people of Western Punjab in Pakistan, whereas Gurmukhi is used by most people of Eastern Punjab in India. The natural written text in Shahmukhi script has missing short vowels and other diacritical marks. Additionally, the presence of ambiguous character having multiple mappings in Gurmukhi script cause ambiguity at character as well as word level while transliterating Shahmukhi text into Gurmukhi script. In this paper we focus on the word level ambiguity problem. The ambiguous Shahmukhi word tokens have many interpretations in target Gurmukhi script. We have proposed two different algorithms for Shahmukhi word disambiguation. The first algorithm formulates this problem using a state sequence representation as a Hidden Markov Model (HMM). The second approach proposes n-gram model in which the joint occurrence of words within a small window of size ± 5 is used. After evaluation we found that both approaches have more than 92% word disambiguation accuracy.
A Successful Strategy to Integrate Sex and Gender Medicine into a Newly Developed Medical Curriculum.

BACKGROUND A new modular, outcome-based, interdisciplinary curriculum was introduced for undergraduate medical education at one of the largest European medical faculties. A key stated institutional goal was to systematically integrate sex and gender medicine and gender perspectives into the curriculum in order to foster adequate gender-related knowledge and skills for future doctors concerning the etiology, pathogenesis, clinical presentation, diagnosis, treatment, and research of diseases. METHODS A change agent was integrated directly into the curriculum development team to facilitate interactions with all key players of the curricular development process. The gender change agent established a supporting organizational framework of all stakeholders, and developed a 10-step approach including identification, selection, placing relevant sex and gender medicine-related issues in the curricular planning sessions, counseling of faculty members, and monitoring of the integration achieved. RESULTS With this approach, quantitatively sex and gender medicine-related content was widely integrated throughout all teaching and learning formats and from early basic science to later clinical modules (94 lectures, 33 seminars, and 16 practical courses). Gender perspectives involve 5% of the learning objectives and represent an integral part of the assessment program. Qualitatively, the relevance of gender (sociocultural) differences was combined with sex (biological) differences in disease manifestation throughout the curriculum. CONCLUSIONS The appointment of a change agent facilitates the development of systematic approaches that can be a key and serve as practice models to successfully integrate new overarching curricular perspectives and dimensions--in this case sex and gender medicine--into a new medical curriculum.
Generalization of trim and fill for application in meta‐regression

Trim and fill is a popular method of accounting for publication bias in meta‐analysis. However, the use of trim and fill is limited to the setting in which all meta‐analyzed studies represent a true common effect. In many practical settings, within‐study effect estimates are a function of some covariate. Because methods of accounting for publication bias in meta‐regression have received little attention, we propose here a generalization of trim and fill for application in meta‐regression. The proposed algorithm preserves the computational features of trim and fill and adds only an assumption of symmetry in the hypothesized distribution of the measured covariate. By simulation, we evaluate properties (mean bias, root mean squared error, and coverage probability) of meta‐regression parameter estimates and corresponding confidence intervals with application of the proposed algorithm in a range of scenarios, including violation of the aforementioned assumption of symmetry. We also evaluate the performance of common estimators of the number of suppressed studies. In general, we show that the proposed algorithm is successful in identifying suppression of studies and reducing the bias in regression parameters derived from the analysis of the augmented set of studies. We apply the proposed algorithm to an analysis of the effect of cognitive–behavioral therapy on the risk of recidivism. Copyright © 2012 John Wiley & Sons, Ltd.
Hypersensitivity to nonsteroidal anti‐inflammatory drugs (NSAIDs) – classification, diagnosis and management: review of the EAACI/ENDA # and GA2LEN/HANNA *

To cite this article: Kowalski ML, Makowska JS, Blanca M, Bavbek S, Bochenek G, Bousquet J, Bousquet P, Celik G, Demoly P, Gomes ER, Niżankowska‐Mogilnicka E, Romano A, Sanchez‐Borges M, Sanz M, Torres MJ, De Weck A, Szczeklik A, Brockow K. Hypersensitivity to nonsteroidal anti‐inflammatory drugs (NSAIDs) – classification, diagnosis and management: Review of the EAACI/ENDA and GA2LEN/HANNA. Allergy 2011; 66: 818–829.
UDP-Glucose 4-Epimerase Isoforms UGE2 and UGE4 Cooperate in Providing UDP-Galactose for Cell Wall Biosynthesis and Growth of Arabidopsis thaliana[W][OA]

Five Arabidopsis thaliana genes that encode UDP-glucose 4-epimerase (UGE) and represent two ancient plant UGE clades might be involved in the regulation of cell wall carbohydrate biosynthesis. We tested this hypothesis in a genome-wide reverse genetic study. Despite significant contributions of each gene to total UGE activity, none was essential for normal growth on soil. uge2 uge4 displayed dramatic general growth defects, while other mutant combinations were partially aberrant. UGE2 together with UGE3 influenced pollen development. UGE2 and UGE4 synergistically influenced cell wall galactose content, which was correlated with shoot growth. UGE2 strongly and UGE1 and UGE5 lightly supported UGE4 in influencing root growth and cell wall galactose content by affecting galactan content. By contrast, only UGE4 influenced xyloglucan galactosylation in roots. Secondary hypocotyl thickening and arabinogalactan protein carbohydrate structure in xylem parenchyma depended on the combination of UGE2 and UGE4. As opposed to cell wall galactose content, tolerance to external galactose strictly paralleled total UGE activity. We suggest a gradual recruitment of individual UGE isoforms into specific roles. UGE2 and UGE4 influence growth and cell wall carbohydrate biosynthesis throughout the plant, UGE3 is specialized for pollen development, and UGE1 and UGE5 might act in stress situations.