Miracle-dz/UniFAR-FTUs huggingface dataset:
Entrepreneurial identity in the care sector: navigating the contradictions

Purpose – The purpose of this paper is to explore how the business and research context influences how female entrepreneurs construct their identities.Design/methodology/approach – Focussing specifically on the care work sector, the analysis of interview transcripts explores how participants struggle to establish a positive identity through reconciling the contradictory subject positions produced at the intersection of entrepreneurialism and caring.Findings – The accounts reveal a silencing of the participants entrepreneurial identity and an embracing of their female identity, reflected in the mobilisation of a number of highly gendered “selves”. This is explained in terms of the participants' desire for legitimacy and integrity, principally in the eyes of their employees, something which is itself prompted by the precariousness of their position as female business owners in this sector.Research limitations/implications – The identity work is theorised at a structural level, reinforcing the need for futur.
Transportation Into Narrative Worlds: The Role of Prior Knowledge and Perceived Realism

"Transportation into a narrative world" (Green & Brock, 2000, 2002) has been identified as a mechanism of narrative impact. A transported individual is cognitively and emotionally involved in the story and may experience vivid mental images. In the study reported here, undergraduate participants (N = 152) read a narrative about a homosexual man attending his college fraternity reunion, rated their transportation into the story, rated the perceived realism of the story, and responded to statements describing story-relevant beliefs. Transportation was positively correlated with perceived realism. Furthermore, individuals with prior knowledge or experience relevant to the themes of the story (e.g., had homosexual friends or family members, were knowledgeable about American fraternities) showed greater transportation into the story. Highly transported readers showed more story-consistent beliefs, and the positive relationship between transportation and story-consistent beliefs held for those both with and without previous relevant experience.
Differential regulation of the activity of deleted in liver cancer 1 (DLC1) by tensins controls cell migration and transformation

The epithelial growth factor receptor plays an important role in cell migration and cancer metastasis, but the underlying molecular mechanism is not fully understood. We show here that differential regulation of the rhodopsin-GTPase-activating (Rho-GAP) activity of deleted in liver cancer 1 (DLC1) by tensin3 and COOH-terminal tensin-like protein (cten) controls EGF-driven cell migration and transformation. Tensin3 binds DLC1 through its actin-binding domain, a region that is missing in cten, and thereby releases an autoinhibitory interaction between the sterile alpha motif and Rho-GAP domains of DLC1. Consequently, tensin3, but not cten, promotes the activation of DLC1, which, in turn, leads to inactivation of RhoA and decreased cell migration. Depletion of endogenous tensin3, but not cten, augmented the formation of actin stress fibers and focal adhesions and enhanced cell motility. These effects were, however, ablated by an inhibitor of the Rho-associated protein kinase. Importantly, activation of DLC1 by tensin3 or its actin-binding domain drastically reduced the anchorage-independent growth of transformed cells. Our study therefore links dynamic regulation of tensin family members by EGF to Rho-GAP through DLC1 and suggests that the tensin-DLC1-RhoA signaling axis plays an important role in tumorigenesis and cancer metastasis, and may be explored for cancer intervention.
Testing the boundary conditions for processing irrelevant location information: The cross-task Simon effect

The Simon effect denotes superior performance when stimulus and response positions correspond than when they do not, even when stimulus position is irrelevant. Usually, this effect is attributed to the automatic formation of a spatial stimulus code that interferes with response selection. Recent evidence, however, called the hypothesis of automatic processing of stimulus position into question. The present study aimed at providing a strong test of this hypothesis. In two experiments, a dual-task procedure was employed. The primary task was an auditory-manual four-choice task (S1-R1 task). The secondary task was a visual encoding task (S2-R2 task), and S2 followed S1 with a variable stimulus onset asynchrony (SOA). Horizontal position of S2, which was irrelevant for both tasks, was also varied, and the effect of spatial S2-R1 correspondence was investigated. Experiment 1 showed dual-task impairment in visual encoding, and a cross-task Simon effect at short SOAs. That is, S2 position affected R1 selection, although less capacity was available for deliberately processing S2 position. In addition, Experiment 2 revealed the absence of the cross-task Simon effect when the target appeared simultaneously with a contralateral distractor. Together, the results suggest that encoding of stimulus position can run automatically, on the basis of an exogenous attention shift towards stimulus location.
A study on partial face recognition of eye region

In this preliminary study, we have investigated the human eye as an important part of face for personal authentication under certain restricted circumstances related to face occlusion, individual privacy concerns and religious practices. Although this part of face is not as unique as full-face, but it offers much higher computational efficiency with minimum processing steps, and minimum storage capacity as compared to full-face. In our experiments, the frontal human eye images are generated from Essex dataset with 153 subjects. The images are tested with non-negative matrix factorization (NMF), local NMF (LNMF) and spatially confined NMF (SFNMF) respectively. Our experiments show that LNMF performs most optimally to attain 95.12% recognition rate, follow by SFNMF and NMF, which achieve 94.48% and 93.23%, respectively. It is evidenced that LNMF and SFNMF performs better than sole plain NMF. Besides, another goal of this paper is to study the influence of r, to which degree the basis number is sufficient to achieve the optimal recognition rate.
Methodology of measurement for energy consumption of applications

For IT systems, energy awareness can be improved in two ways, (i) in a static or (ii) in a dynamic way. The first way leads to building energy efficient hardware that runs fast and consumes only a few watts. The second way consists of reacting to instantaneous power consumption, and of taking decisions that will reduce this consumption.
Anchoring Symbols to Sensor Data: Preliminary Report

Anchoring is the process of creating and maintaining the correspondence between symbols and percepts that refer to the same physical objects. Although this pro- cess must necessarily be present in any physically em- bedded system that includes a symbolic component (e.g., an autonomous robot), no systematic study of anchoring as a problem per se has been reported in the literature on intelligent systems. In this paper, we propose a domain-independent deflnition of the anchor- ing problem, and identify its three basic functionalities: flnd, reacquire, and track. We illustrate our deflnition on two systems operating in two difierent domains: an unmanned airborne vehicle for tra-c surveillance; and a mobile robot for o-ce navigation.
Adding modeled speech-generating device use to a naturalistic language intervention facilitates generalized communicative spoken utterances immediately after treatment and generalized gains on declarative use 12 weeks after treatment ends in children with ASD who began treatment in the “word combina

This review provides a summary and appraisal commentary on the treatment review by Kasari, C. , Kaiser, A. , Goods, K. , Nietfeld, J., Mathy, P., Landa, R. , Murphy, S. , & Almirall, D. (2014). Communication interventions for minimally-verbal children with autism: A sequential multiple assignment randomization trial. Journal of the American Academy of Child & Adolescent Psychiatry, 53, 635–646. Funding: This study was funded by Autism Speaks. Authors reported receiving support from the Health Resources and Services Administration, the National Institutes of Health, Autism Speaks, the Institute of Education Sciences, the Centers for Disease Control and Prevention, the Simons Foundation Autism Research Initiative, and Ride On for Autism. Drs. Kasari and Kaiser are authors of the blended JASPER-EMT model.
Achieving reproducibility by combining provenance with service and workflow versioning

Capturing and exploiting provenance information is considered to be important across a range of scientific, medical, commercial and Web applications, including recent trends towards publishing provenance-rich, executable papers. This article shows how the range of useful questions that provenance can answer is greatly increased when it is encapsulated into a system that can store and execute both current and old versions of workflows and services. e- Science Central provides a scalable, secure cloud platform for application developers. They can use it to upload data -- for storage on the cloud -- and services, which can be written in a variety of languages. These services can then be combined through workflows which are enacted in the cloud to compute over the data. When a workflow runs, a complete provenance trace is recorded. This paper shows how this provenance trace, used in conjunction with the ability to execute old versions of services and workflows (rather than just the latest versions) can provide useful information that would otherwise not be possible, including the key ability to reproduce experiments and to compare the effects of old and new versions of services on computations.
Naturally Occurring Changes in Physical Activity Are Inversely Related to Depressive Symptoms During Early Adolescence

Objective: We examined the relationship between naturally occurring changes in physical activity and depressive symptoms across a 2-year period among adolescent boys and girls. Methods: Participants (N = 4594) reported their frequency of physical activity outside of school and completed the Center for Epidemiological Studies Depression scale in the Fall of 1998 (beginning of 7th grade; baseline data), Spring of 1999 (end of 7th grade; interim data), and Spring of 2000 (end of 8th grade; follow-up data). Results: Latent growth modeling indicated that a 1 SD unit change in the frequency of leisure-time physical activity was inversely related to a . 25 SD unit change in depressive symptoms. This relationship was attenuated but remained statistically significant when simultaneously controlling for the confounding variables of sex, socioeconomic status, smoking, alcohol consumption, and the value participants placed on their health, appearance, and achievement. Conclusions: Naturally occurring changes in physical activity were negatively related with changes in depressive symptoms. The results encourage randomized controlled trials to experimentally determine whether an increase in physical activity reduces depression risk among adolescent boys and girls.
Changes in the Testis Interstitium of Sprague Dawley Rats from Birth to Sexual Maturity1

Abstract Changes in the rat testis interstitium from birth to adulthood were studied using Sprague Dawley rats of 1, 7, 14, 21, 28, 40, 60, and 90 days of age. Our objectives were 1) to understand the fate of the fetal Leydig cells (FLC) in the postnatal rat testis, 2) to determine the volume changes in testicular interstitial components and testicular steroidogenic capacity in vitro with age, 3) to differentially quantify FLC, adult Leydig cells (ALC), and different connective tissue cell types by number and average volume, and 4) to investigate the relationship between mesenchymal and ALC numbers during testicular development. FLC were present in rat testes from birth to 90 days, and they were the only steroidogenic cells in the testis interstitium at Days 1 and 7. Except for FLC, all other interstitial cell numbers and volumes increased from birth to 90 days. The average volume of an FLC and the absolute volume of FLC per testis were similar at all ages except at Day 21, when lower values were observed for both parameters. FLC number per testis remained constant from birth through 90 days. The observations suggested that the significance of FLC in the neonatal-prepubertal rat testis is to produce testosterone to activate the hypothalamo-hypophyseal-testicular axis for the continued development of the male reproductive system. ALC were the abundant Leydig cell type by number and absolute volume per testis from Day 14 onwards. The absolute numbers of ALC and mesenchymal cells per testis increased linearly from birth to 90 days, with a slope ratio of 2:1, respectively, indicating that the rate of production of Leydig cells is 2-fold greater than that of mesenchymal cells in the postnatal rat testis through 90 days. In addition, this study showed that the mesenchymal cells are an active cell population during testis development and that their numbers do not decrease but increase with Leydig cell differentiation and testicular growth up to sexual maturity (90 days).
"Spirituality": "Weasel-Word" or Gateway to New Understanding?

Visiting the Samuel Palmer Exhibition at the British Museum, I was struck, not only by the spiritual power of the paintings, especially in the late Shoreham period such as, my favorite: The Magic Apple Tree (circa 1830)—but how Palmer appeared to bring both Christian and Pantheistic themes into his work. The museum’s exhibition collator remarks that Palmer saw the fruitfulness of the earth as an intimation of Divine creativity. The artist sought to capture “The essential vivifying spirit, vital spark” (Palmer’s words) of the physical world in which we live. I was reminded as I moved from The Magic Apple Tree, to In a Shoreham Garden, and The Golden Valley, how these paintings had been used by a record company when they had issued all of Ralph Vaughan Williams’ orchestral and choral works in the 1970s, to mark his anniversary. Vaughan Williams was not a signed up Christian, but many of his choral works express a strong yearning for the transcendent using Christian imagery. The day before I visited the Palmer exhibition, I listened to Professor Robert Winston on Start the Week (28th November, 2005), in which he spoke of his BBC series The Story of God (Winston, 2005). As a scientist, Winston is intrigued as to why humans seek the transcendent. He continually refers to this desired other as “God,” although I think it would be more accurate to call it a search for the transcendent. Winston puzzles over why there appears to be “a God-shaped hole” within humanity (Start the Week, November, 28, 2005), and again, as a scientist, postulates that: “the more we understand about science, the less we understand about the Universe. ” In the light of the most popular films and books at present, the search for something beyond ourselves appears to be very much at the center, rather than at the periphery of humanity’s consciousness at the present time. Reading Philip Pullman’s His Dark Materials trilogy, and reading his various essays, we are struck by his articulation of the human search:
Intelligent Vehicular Transportation System (InVeTraS)

InVeTraS (intelligent vehicular transportation system) is proposed as a vehicle-to-vehicle (V2V) anti-collision mechanism that determines, estimates and absolves collision courses between two or more vehicles based on a correlative and cooperative wireless networking concept. The problem of collision avoidance is abstracted to the generic problem of location awareness and subsequent periodic information exchange (between vehicles). To enable location awareness, the mechanism uses one of two techniques: a global positioning system (GPS) receiver aided with dead-reckoning sensors or a RADAR based measurement system. Two nearby vehicles periodically exchange information about their own movement in terms of exact position and local clock time. Using these inputs, vehicles determine whether or not they are on a collision course with each another. A communication cluster (based on the concept of mobile ad-hoc peer-to-peer networking) is formed, that facilitates the development of a vehicular network characterized by self-organization, fault-tolerance, scalability, cooperation and cost efficiency. These characteristics enable avoidance of collision between vehicles in an adaptive and dynamic set up. The paper simulates the proposed InVeTraS concept over a torus topology emulating the streets of Manhattan.
Participants' Perception of Therapeutic Factors in Group Counseling

Yalom (1985) hypothesizes that clients'perception of therapeutic factors depend on the stage of group development and on client individual difference variables. The hypotheses were tested using the critical incident reports obtained from 18 participants in three 11-session counseling groups. Judges classified the critical incident reports into therapeutic factor cat egories. Perceptions of the relative importance of these factors were analyzed by stage of group development (early versus late) and by client interpersonal orientation (affiliative versus nonaffiliative and dominant versus submissive). Results indicate differences in the relative importance of the therapeutic factors as seen by the group participants for stage of group development and for participants' affiliativeness. No differences were found for dom inant versus submissive clients. The results are discussed in relation to theories of group de velopment, clinical group practice, and interpersonal conceptualization of counseling and therapy.
Evaluation of Matrix Metalloproteinases in Atherosclerosis Using a Novel Noninvasive Imaging Approach

Objective—Despite great advances in our knowledge, atherosclerosis continues to kill more people than any other disease in the Western world. This is because our means of identifying truly vulnerable patients is limited. Prediction of atherosclerotic plaque rupture may be addressed by MRI of activated matrix metalloproteinases (MMPs), a family of enzymes that have been implicated in the vulnerability of plaques prone to rupture. This study evaluated the ability of the novel gadolinium-based MRI contrast agent P947 to target MMPs in atherosclerotic plaques. Methods and Results—The affinity of P947 toward activated MMPs was demonstrated in vitro. The affinity and specificity of P947 toward matrix metalloproteinase (MMP)-rich plaques was evaluated both in vivo using ApoE−/− mice and ex vivo in hyperlipidemic rabbits. Gadolinium content quantification and MRI showed a preferential accumulation of P947 in atherosclerotic lesions compared with the nontargeted reference compound, Gd-DOTA. The ex vivo assay on rabbit plaques revealed a higher uptake of P947. Moreover, using human carotid artery endarterectomy specimens, P947 facilitated discrimination between histologically defined MMP-rich and MMP-poor plaques. An in vivo MRI investigation in mice revealed that P947 greatly improved the ability to visualize and delineate atherosclerotic plaques. Conclusions—P947 may be a useful tool for the detection and characterization of the MMP-rich atherosclerotic plaques.
Nuclear Import of Influenza Virus RNA Can Be Mediated by Viral Nucleoprotein and Transport Factors Required for Protein Import (*)

We have fluorescently labeled one of the eight genomic segments of influenza virus RNA and a recombinant influenza viral protein, the nucleoprotein (NP), to investigate the requirement for their uptake into nuclei of digitonin-permeabilized cells. We found that the influenza viral NP behaves like a nuclear localization sequence (NLS) containing protein. Thus, at 0°C it docks at the nuclear envelope only in the presence of the heterodimeric karyopherin (either karyopherin α1β or karyopherin α2β), and docking is competitively inhibited by an unlabeled NLS containing substrate. Like other NLS-containing proteins, at 20°C NP is imported into the nucleus after further addition of the GTPase Ran and of p10. In contrast, the fluorescently labeled, 890-nucleotide-long viral RNA segment does not dock to the nuclear envelope or enter the nucleus either in the presence of exogenous cytosol or of karyopherin heterodimer, Ran, and p10. However, in the presence of NP the RNA is able to dock and enter the nucleus with transport requirements indistinguishable from those for docking and entry of NP. These data indicate that uptake of the influenza virus RNA segment is not via a signal in the RNA but via an NLS of a viral protein such as NP.
Achievement Goal Questionnaire

The aim of this study was to test the gender invariance of the Chinese version of the Achievement Goal Questionnaire (AGQ-C) utilizing a sample of 1,115 Chinese university students. Multi-group confirmatory factor analysis supported the configural, metric, and scalar invariance of the AGQ-C across genders. Analyses also revealed that the latent factor means were different in male and female students.
Deflation Techniques for an Implicitly Restarted Arnoldi Iteration

A deflation procedure is introduced that is designed to improve the convergence of an implicitly restarted Arnoldi iteration for computing a few eigenvalues of a large matrix. As the iteration progresses, the Ritz value approximations of the eigenvalues converge at different rates. A numerically stable scheme is introduced that implicitly deflates the converged approximations from the iteration. We present two forms of implicit deflation. The first, a locking operation, decouples converged Ritz values and associated vectors from the active part of the iteration. The second, a purging operation, removes unwanted but converged Ritz pairs. Convergence of the iteration is improved and a reduction in computational effort is also achieved. The deflation strategies make it possible to compute multiple or clustered eigenvalues with a single vector restart method. A block method is not required. These schemes are analyzed with respect to numerical stability, and computational results are presented.
Interactive POMDPs: properties and preliminary results

This paper presents properties and results of a new framework for sequential decision-making in multiagent settings called interactive partially observable Markov decision processes (I-POMDPs). I-POMDPs are generalizations of POMDPs, a well-known framework for decision-theoretic planning in uncertain domains, to cases when an agent needs to plan a course of action in an environment populated by other agents.
Rho Family GTPases Are Required for Activation of Jak/STAT Signaling by G Protein-Coupled Receptors

ABSTRACT As do cytokine receptors and receptor tyrosine kinases, G protein-coupled receptors (GPCRs) signal to Janus kinases (Jaks) and signal transducers and activators of transcription (STATs). However, the early biochemical events linking GPCRs to this signaling pathway have been unclear. Here we show that GPCR-stimulated Rac activity and the subsequent generation of reactive oxygen species are necessary for activating tyrosine phosphorylation of Jaks and STAT-dependent transcription. The requirement for Rac activity can be overcome by addition of hydrogen peroxide. Expression of activated mutants of Rac1 is sufficient to activate Jak2 and STAT-dependent transcription, and the activation of Jak2 correlates with the ability of Rac1 to bind to NADPH oxidase subunit p67phox. We further show that GPCR agonists stimulate tyrosine phosphorylation of STAT1 and STAT3 proteins in a Rac-dependent manner. The tyrosine phosphorylation of STAT3 is biphasic; the first peak of phosphorylation is weak and correlates with rapid activation of Jaks by GPCRs, whereas the second peak is stronger and requires the synthesis of an autocrine factor. Rho also plays an essential role in the induction of STAT transcriptional activity. Our results highlight a novel role for Rho GTPases in mediating the regulatory effects of GPCRs on STAT-dependent gene expression.