Miracle-dz/UniFAR-FTUs huggingface dataset:
Study on the backscattering characteristic of typical earth substances in northwest of Chaina

The S-band and C-band FM-CW land-based radar scatterometers were used to measure the backscattering coefficient of a variety of typical earth substances in northwest of China, including: bare soil, frozen soil, bulrush and maize etc. under the different time and different wave band and different polarized condition. First of all, the measurement principle and performance parameters of scatterometer were introduced, the detailed experimental plans and measurements specifications were developed. Based on them, the various units of measurement were completed successfully. The measurement process of scatterometer was briefly introduced in this work. according to different scattering mechanisms, features are divided into two categories: surface scattering and volume scattering, and analyzed these Scattering Characteristics and the reasons for these differences; combining with the corresponding earth substances scattering model, quantitative studying a function between the backscattering coefficient and surface parameters, getting different surface parameters of features by inversion, and analysis of a variety of influencing factors by comparing the measured datas.
Recovery of 13C in breath from NaH13CO3 infused by gut and vein: effect of feeding.

Estimates of substrate oxidation obtained from appearance of 13C or 14C from tracers in breath must be corrected for retention of labeled carbon in the body. We aimed to determine the effect of a defined experimental diet and metabolic status on recovery of infused Na [13C]bicarbonate in breath. Six healthy male subjects consumed an experimental diet for 7 days before receiving a continuous infusion of formula without tracer on day 8 and received either an intragastric (ig) or intravenous (iv) infusion of Na [13C]bicarbonate on day 9 or 11 during a 4-h postabsorptive (PA), 4-h continuously fed period. A trend toward increasing PA breath enrichment during the first 7 diet days approached statistical significance (P = 0.051), whereas breath enrichments measured 3 h postbreakfast were consistently higher than PA values throughout and did not change over the 7-day period. Breath enrichments during a 4-h continuous ig infusion of formula without tracer on day 8 rose 2.0 +/- 0.5 atom percent excess (APE). 10(-3) above base line (P less than 0.001, ANOVA). In the tracer studies, breath enrichments were similar for the ig and iv routes of tracer infusion. For the ig infusion the fraction of infused Na [13C]bicarbonate recovered in breath as 13CO2 was 0.74 +/- 0.02 for the PA period and 0.79 +/- 0.02 for the fed period. For the iv infusion the fraction recovered was 0.70 +/- 0.04 for the PA period and 0.82 +/- 0.03 for the fed period. Fractional recoveries were not significantly different for ig and iv routes of administration but were different for PA and fed periods (P less than 0.0001, 2-way ANOVA). The fractional recoveries for the fed period obtained here were similar to the value 0.81 reported in a number of other studies. Recovery of tracer in breath increased linearly with O2 uptake and CO2 production, suggesting that factors affecting respiratory gas exchange may alter recovery. We conclude that the primary factor determining label recovery is the immediate and recent nutritional status of the host.
Curcumin Intake Affects miRNA Signature in Murine Melanoma with mmu-miR-205-5p Most Significantly Altered

Melanoma is the most aggressive form of skin cancer with estimated 48,000 deaths per year worldwide. The polyphenol curcumin derived from the plant Curcuma longa is well known for its anti-inflammatory and anti-cancerogenic properties. Accordingly, dietary intake of this compound may be suitable for melanoma prevention. However, how this compound affects basic cellular mechanisms in developing melanoma still remains elusive. Therefore, the aim of this study was to investigate for the first time the impact of oral curcumin administration on the miRNA signature of engrafting melanoma. For this purpose, the effects of a 4% curcumin diet were tested on melanoma, which were established by injection of murine B78H1 cells in the flank of C57BL/6 mice. Curcumin diet or standard chow (control) was administered two weeks prior to injection of tumor cells until termination of the experiment. High throughput chip-based array analysis was deployed to detect alterations in the miRNA signature of the tumors. Curcumin treatment significantly reduced the growth of the flank tumors. Furthermore the miRNA expression signature in tumors was substantially altered by curcumin intake with mmu-miR-205-5p over 100 times higher expressed when compared to controls. The expression levels of identified key miRNAs in the tumor samples were confirmed by quantitative real-time polymerase chain reaction (qRT-PCR). A comparable expression pattern of these miRNAs was also detected in other curcumin-treated melanoma cell lines under in vitro conditions. Putative targets of curcumin-induced up-regulated miRNAs were enriched in ‘o-glycan biosynthesis’, ‘endoplasmatic reticulum protein processing’ and different cancer-related pathways. Western Blot analyses revealed that of these targets anti-apoptotic B-cell CLL/lymphoma 2 (Bcl-2) and proliferating cell nuclear antigen (PCNA) were significantly down-regulated in curcumin-treated tumors. These findings demonstrate a profound alteration of the miRNA expression signature in engrafting curcumin-treated melanoma with mmu-miR-205-5p being up-regulated most significantly.
How does vacuum forming affect Pelite mechanical properties?

Pelite® is a polyethylene closed cell foam commonly used as an interface material in prosthetics. Both normal and vacuum-formed Pelite were tested under compression and under shear loading. For shear testing, the results were not significantly different for normal and vacuum-formed Pelite. For normal Pelite, the slope of the stress-strain curve was 1.17MPa (±0.14) while for vacuum-formed Pelite it was 1.24MPa (±0.22). Compressive results, however, were significantly different. Below 80kPa of applied compression, the slope of the stress-strain curve for normal Pelite was 0.99MPa (±0.11) while for vacuum formed Pelite it was 0.72MPa (±0.12). Between 80kPa and 200kPa of applied compression, the slope of the stress-strain curve for normal Pelite was 0.45MPa (±0.03) while for vacuum formed Pelite it was 0.55MPa (±0.05). Reasons for the differences and their significance to interface mechanics and computer-aided prosthesis design are discussed.
Research on the Work Experiences of Lesbian, Gay, and Bisexual People: An Integrative Review of Methodology and Findings

Abstract The methodology and content of nine published studies on the workplace experiences of lesbian, gay, and bisexual people are examined. Findings are integrated within five areas of common content: the pervasiveness of discrimination in the workplace, formal and informal types of discrimination, fear of discrimination, variability of workers in their openness about sexual orientation, and correlates of workers’ degree of openness versus concealment of sexual orientation. The methodology employed in existing research is examined focusing specifically on sampling, data collection, and analyses and presentation of results. Recommendations for improving those aspects of methodology in future studies are made. Finally, ideas for expanding the scope of the content and methodology of research concerning the workplace experiences of this population are presented.
Turbo Equalization for Receivers with Unreliable Buffer Memory

In this paper the effect of unreliable buffer memory on Turbo equalization is investigated. Under the assumption that the resulting bit errors are uniformly and independently distributed on receive and LLR buffer output, the effect of unreliable memory on the channel capacity is analyzed. It is further shown, that extrinsic information transfer and bit error rate (BER) performance of a conventional Turbo Equalizer are heavily degraded. Based on these observations a fault tolerant (FT) Turbo Equalizer is derived, which considers the memory error characteristics by using a modified transition metric for the involved MAP equalizer and decoder. It is demonstrated, that the FT Turbo Equalizer can effectively compensate memory errors and thus yields a significantly improved BER performance.
Approaching clinical proteomics: current state and future fields of application in fluid proteomics

Abstract The field of clinical proteomics offers opportunities to identify new disease biomarkers in body fluids, cells and tissues. These biomarkers can be used in clinical applications for diagnosis, stratification of patients for specific treatment, or therapy monitoring. New protein array formats and improved spectrometry technologies have brought these analyses to a level with potential for use in clinical diagnostics. The nature of the human body fluid proteome with its large dynamic range of protein concentrations presents problems with quantitation. The extreme complexity of the proteome in body fluids presents enormous challenges and requires the establishment of standard operating procedures for handling of specimens, increasing sensitivity for detection and bioinformatical tools for distribution of proteomic data into the public domain. From studies of in vitro diagnostics, especially in clinical chemistry, it is evident that most errors occur in the preanalytical phase and during implementation of the diagnostic strategy. This is also true for clinical proteomics, and especially for fluid proteomics because of the multiple pretreatment processes. These processes include depletion of high-abundance proteins from plasma or enrichment processes for urine where biological variation or differences in proteolytic activities in the sample along with preanalytical variables such as inter- and intra-assay variability will likely influence the results of proteomics studies. However, before proteomic analysis can be introduced at a broader level into the clinical setting, standardization of the preanalytical phase including patient preparation, sample collection, sample preparation, sample storage, measurement and data analysis needs to be improved. In this review, we discuss the recent technological advances and applications that fulfil the criteria for clinical proteomics, with the focus on fluid proteomics. These advances relate to preanalytical factors, analytical standardization and quality-control measures required for effective implementation into routine laboratory testing in order to generate clinically useful information. With new disease biomarker candidates, it will be crucial to design and perform clinical studies that can identify novel diagnostic strategies based on these techniques, and to validate their impact on clinical decision-making. Clin Chem Lab Med 2009;47:724–44.
Weight-Bearing in the Nonoperative Treatment of Acute Achilles Tendon Ruptures: A Randomized Controlled Trial.

BACKGROUND The rate of Achilles tendon ruptures is increasing, but there is a lack of consensus on treatment of acute injuries. The purpose of this trial was to compare outcomes of weight-bearing casts with those of traditional casts in the treatment of acute Achilles tendon ruptures. METHODS Eighty-four patients with an acute Achilles tendon rupture were recruited over a two-year period. Patients were randomized to be treated with either a weight-bearing cast with a Böhler iron or a non-weight-bearing cast for eight weeks. Patients underwent muscle dynamometry testing at six months, with additional follow-up at one and two years. The primary outcomes that were assessed were the rerupture rate and the time taken to return to work. Secondary outcomes included return to sports, ankle pain and stiffness, footwear restrictions, and patient satisfaction. RESULTS There were no significant differences between groups with regard to patient demographics or activity levels prior to treatment. At the time of follow-up at two years, one (3%) of the thirty-seven patients in the weight-bearing group and two (5%) of the thirty-seven in the non-weight-bearing group had sustained a rerupture (p = 0.62). The patients in the weight-bearing group experienced less subjective stiffness at one year. There were no significant differences in time taken to return to work, Leppilahti scores, patient satisfaction, pain, or return to sports between the groups. CONCLUSIONS Use of weight-bearing casts for the nonoperative treatment of Achilles tendon ruptures appears to offer outcomes that are at least equivalent to those of non-weight-bearing casts. The overall rerupture rate in this study was low, supporting the continued use of initial nonoperative management for the treatment of acute Achilles tendon ruptures. LEVELS OF EVIDENCE Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
Digital Image Watermarking with 1 / T Rate Forward Error Correction to Malicious Attacks

In this paper, a copyright protection method for digital image with 1/T rate forward error correction (FEC) is proposed. In the proposed method, the original image is lossless and the watermark is robust to malicious attacks including geometric attacks such as scaling, rotation, cropping, print-photocopy-scan, and scaling-cropping attacks and nongeometric attacks such as low-pass filtering, sharpening, JPEG compression attacks. The watermark logo is fused with noise bits to improve the security, and later XORed with the feature value of the image by 1/T rate FEC. During extraction, the watermark bits are determined by majority voting, and the extraction procedure needs neither the original image nor the watermark logo. Experimental results show that not only the image is lossless but also the proposed method can effectively resist the common geometric and nongeometric attacks. Since the proposed method is based on spatial domain and transferring to frequency domain is not needed, the embedding and extraction performances are improved.
Effects of Rote Versus Note Presentations on Rhythm Learning and Retention

This study examined the effects of aural and visual approaches to rhythm reading and short-term retention. Second- and sixth-grade students were presented with two-measure rhythm patterns in four modes: (1) audio-rhythm, (2) audio-mnemonics, (3) (audio) visual-rhythm, and (4) (audio) visual-mnemonics. Raw data consisted of the number of trials necessary for the correct performance of the rhythms on a woodblock. Results indicated that the simultaneous use of auditory and visual channels facilitates learning and retention of rhythms at both grade levels. Maturation is significant in the acquisition of rhythms, in that older students learned the patterns twice as quickly as the younger children, regardless of presentation mode. Factors concerning the mnemonics, short-term memory, and the development of music literacy were discussed.
Differential time course of implicit and explicit cueing by colour and orientation in visual search

Using a cued conjunction search task, Anderson, Heinke, and Humphreys (2010) demonstrated larger effects from cueing target colour than from cueing target orientation. In this study, we separated the implicit (nonexpectation-dependent) and explicit (expectation-dependent) effects of orientation and colour visual cues. In Experiment 1, we replicated the original findings for short cue durations (100–200 ms), demonstrating that cues matching the physical property of the target on 80% of trials exert a rapid effect on search. These early cueing effects on reaction times were supported by evidence of guidance from cues on early eye movements. Experiment 2 introduced a feature to the cue that randomly matched the colour or orientation of the target. When cue orientation was predictive, there were strong implicit effects based on whether the colour of the cue and target matched. When cue colour was predictive, there were only weak effects from the cue's orientation. Implicit effects from cue colour remained when orientation-predictive cues were used and colour was unlikely to predict the target (Experiment 3). The data suggest that strong effects of colour cueing result from a combination of implicit and explicit processes, whereas effects from orientation cues are largely limited to the explicit guidance of visual search.
On Revision Of The Option-based Approach ToModeling Mortgage Securities

Using risk-neutral martingalemethods together with the intensity-based approach, this paper developsa frameworkthatnot onlygeneralizesbut considerablyextends the option-based approach. We formalize this approach and propose a new variant which promises a better performance. In particular, estimated transaction costs should be closer to those observed on the market. Our general model is not tied to a particular numerical procedure as are option-based mortgage models in the literature. As an example we show that classical Stanton’s model [9] is in fact a variant of a splitting-up, numerical method of the first order applied to our model.
Differential adaptations in GABAergic and glutamatergic systems during ethanol withdrawal in male and female rats.

BACKGROUND There are significant and consistent sex differences in recovery from ethanol withdrawal in our animal model of ethanol dependence. We have also observed significant and varied sex differences in subunit protein levels of gamma-aminobutyric acid A (GABAA) and the N-metheyl-D-aspartate subtype of glutamate receptors occurring with ethanol dependence and withdrawal. Considering the major role of these two systems as targets of ethanol, we wanted to explore additional possible mechanisms underlying changes in GABAergic and glutamatergic responses after chronic ethanol exposure. Therefore, the objective of the present study was to examine GABAergic- and glutamatergic-associated proteins at three days of ethanol withdrawal, when female rats appear to have largely recovered but male rats still display robust signs of withdrawal. METHODS Male and female rats were fed 6% ethanol in a nutritionally complete liquid diet for 14 days according to a pair-fed design; withdrawal was initiated by replacement of the diet with chow. At three days of withdrawal, the cerebral cortex and hippocampus were dissected for use in Western blot analysis. The paired design was maintained throughout all experimental procedures. RESULTS At three days of ethanol withdrawal, we found region-specific and sex-selective alterations in levels of GAD (glutamic acid decarboxylase, GABA synthetic enzyme), GABA and glutamate transporters, and the synapse-associated proteins HSP70, PSD-95, and synaptophysin. There were also several significant differences in transporter function at this time that varied between males and females. CONCLUSIONS Taken together, these findings show differential adaptations of GABAergic and glutamatergic neurotransmission between female and male rats that are associated with withdrawal recovery. This suggests that selective withdrawal-induced neuroadaptations in regulation of these systems' activities underlie, at least in part, sex differences in withdrawal recovery between male and female rats.
Parallel output, liquid flooded flow-focusing microfluidic device for generating monodisperse microbubbles within a catheter

A new method for supplying the liquid phase to a flow focusing microfluidic device (FFMD), designed for the production of monodisperse microbubbles (MBs), is introduced. The FFMD is coupled to a pressurized liquid-filled chamber, avoiding the need for dedicated liquid phase tubing or interconnects from the external field to the microfluidics device. This method significantly reduces the complexity of FFMD fabrication and simplifies the parallelization of FFMDs - an important consideration for increasing MB production rate. Using this new method, flooded FFMDs were fabricated and MB diameter and production rate were measured. The minimum MB size produced was 7.1±0.5 μm. The maximum production rate from a single nozzle FFMD was 333,000, MB/s. Production was increased 1.5-fold using a two nozzle, parallelized device, for a maximum production rate of approximately 500,000 MB/s. In addition to increased production, the flooded design allows for miniaturization, with the smallest FFMD measuring 14.5 × 2.8 × 2.3 mm. Finally, B-mode and intravascular ultrasound images were obtained, highlighting the potential for flooded FFMDs to generate microbubbles in situ in a catheter and immediately thereafter image the same MBs in a target blood vessel.
A novel modulation technique in diffusion based molecular communication and its performance analysis

Molecular communication (MC) is a promising bio-inspired paradigm, in which molecules are used to encode, transmit, and receive information at the nanoscale. One of the main challenges in MC is the inter symbol interference (ISI) caused by the nature of the diffusion channel. One of the main solutions to this problem is to keep the symbol duration as long as possible and avoid all the molecules that may cause ISI in the next symbol duration. On the other hand, long symbol durations lead to very low data rates, even for very short distances. In this paper, a novel molecular communication scheme for diffusion-based communication channels is proposed in order to increase the data rate. The proposed technique employs multiple molecule types simultaneously to reduce the ISI and achieve a better symbol error rate compared to that of the standard modulation technique.
Flows on few paths: Algorithms and lower bounds

The classical network flow theory allows decomposition of flow into several chunks of arbitrary sizes traveling through the network on different paths. In the first part of this article we consider the unsplittable flow problem where all flow traveling from a source to a destination must be sent on only one path. We prove a lower bound of Ω(log m/log log m) on the performance of a general class of algorithms for minimizing congestion where m is the number of edges in a graph. These algorithms start with a solution for the classical multicommodity flow problem, compute a path decomposition, and select one of its paths for each commodity in order to obtain an unsplittable flow. Our result matches the best known upper bound for randomized rounding—an algorithm of this type introduced by Raghavan and Thompson. The k‐splittable flow problem is a generalization of the unsplittable flow problem where the number of paths is bounded for each commodity. We study a new variant of this problem with additional constraints on the amount of flow being sent along each path. We present approximation results for two versions of this problem with the objective to minimize the congestion of the network. The key idea is to reduce the problem under consideration to an unsplittable flow problem while only losing a constant factor in the performance ratio. © 2006 Wiley Periodicals, Inc. NETWORKS, Vol. 48(2), 68–76 2006