Miracle-dz/UniFAR-FTUs huggingface dataset:
Insurance Contracts with One-Sided Ambiguity

In this paper we study contract formation in a standard insurance model with one-sided ambiguity: the agent is ambiguous about the likelihood of relevant events while the insurer does not face ambiguity but is aware of the fact that the agent does. We argue that a contract offer can potentially transfer this informational advantage to the insured. This leads us to model contract formation as a signaling game. We show that both pooling and separating equilibria exist but only one - the most protable full insurance pooling contract - is a perfect sequential equilibrium. We believe this result to be relevant for the following reasons. First, the main idea of the paper is that when we analyze contract formation in the presence of ambiguity the information channeled through contracts needs to be taken into account carefully. Second, it implies that the insurer prefers not to disclose her information, which is an empirically relevant finding. Third, the result easily carries over to any contractual relationship between an expert and an uninformed agent and would predict experts to be reluctant to share information.
Selecting a Location for a City Logistics Facility: A Fuzzy Synthetic Evaluation Method

The strategic location of city logistics facilities may help to establish more efficient urban logistics systems, reduce social and environmental costs of urban freight transport, and improve urban traffic conditions. In addition, it may allow a number of shippers or freight carriers to jointly operate freight vehicles and terminals or information systems while allowing them to have the capability to provide higher levels of services to their customers. This paper considers the problem of selecting a location for a city logistics facility while considering linguistic factors. This paper identifies the important factors in the selection of a location for a city logistics facility by performing a case study which applies the analytic hierarchy process method on data from Chongqing, China. The optimal location in Chongqing is then determined by using the fuzzy synthetic evaluation method. The results of this paper are expected to help municipal governments select appropriate locations for city logistics facilities and quantify the advantages and disadvantages of alternative locations.
Dlic1 deletion impaired cerebellar development in mouse

The cerebellum is an important model system to study Central Nervous System, it has a striking morphology consisting of folia separated by fissures of different lengths, and the molecules controlling the process of cerebellar development have been unclear. In this study, we report an unrecognized contribution of Dlic1 to the postnatal development of murine cerebellum. Dlic1 encodes a light intermediate chain of cytoplasmic dynein 1, it is a subunit unique to the cytoplasmic form of dynein, and how it contributes to dynein function is not fully understood. Our data show that Dlic1 deletion leads to impaired cerebellar development, foliation and fissuration, the volume of the cerebellum was evidently reduced. Consistent with the histological defects, Dlic1 knockout mice show defective motor coordination, this strongly indicates the fundamental role of Dlic1 in cerebellar development and function. Purkinje cells are located within the cerebellum and form synapses with granule cells. In Dlic1-/- mice, Purkinje cells display reduced dendritic complexity and the distribution of dynein in Purkinje cell layer is changed. We also found that Dlic1 deletion reduced the protein levels of dynein subunits and leads to the defective assembling of dynein subunits. These data indicate that Dlic1 may affect cerebellar development through affecting the normal function of dynein. Abbreviations Dlic1 cytoplasmic dynein 1 light intermediate chain CNS central nervous system MEF mouse embryo fibroblast
An Ontology-based Mediator of Clinical Information for Decision Support Systems

Summary Objective: We have been developing a decision support system that uses electronic clinical data and provides alerts to clinicians. However, the inference rules for such a system are difficult to write in terms of representing domain concepts and temporal reasoning. To address this problem, we have developed an ontologybased mediator of clinical information for the decision support system. Methods: Our approach consists of three steps: 1) development of an ontology-based mediator that represents domain concepts and temporal information; 2) mapping of clinical data to corresponding concepts in the mediator; 3) temporal abstraction that creates high-level, interval-based concepts from time-stamped clinical data. As a result, we can write a concept-based rule expression that is available for use in domain concepts and interval-based temporal information. The proposed approach was applied to a prototype of clinical alert system, and the rules for adverse drug events were executed on data gathered over a 3-month period. Results: The system generated 615 alerts. 346 cases (56%) were considered appropriate and 269 cases (44%) were inappropriate. Of the false alerts, 192 cases were due to data inaccuracy and 77 cases were due to insufficiency of the temporal abstraction. Conclusion: Our approach enabled to represent a concept-based rule expression that was available for the prototype of a clinical alert system. We believe our approach will contribute to narrow the gaps of information model between domain concepts and clinical data repositories.
Catharanthus Roseus ( Tapak Dara ) : ” a Controversial ” Medicinal Plant in Indonesia

Herbal medicine industry in Indonesia was shaken when Indonesian National Agency of Drugs and Food control prohibits the development of herbal medicines made from Catharanthus roseus. The reason given is that Catharanthus roseus contains alkaloids causing bone marrow depression. The purpose of this article to explore the effects of both preclinical and clinical pharmacological of Catharanthus roseus. The result of the research shows Catharanthus roseus have many pharmacological effects include: antidiabetic, hypolipidemic, antihypertension, anticancer, antiangiognesis, antispermatogenic, antifungal, antibacteria, antioxidant, wound healing and even hepatoprotective activity.
Constrained Optimisation of Rational Functions for Accelerating Subspace Iteration

Earlier this decade, the so-called FEAST algorithm was released for computing the eigenvalues of a matrix in a given interval. Previously, rational filter functions have been examined as a parameter of FEAST. In this thesis, we expand on existing work with the following contributions: (i) Obtaining well-performing rational filter functions via standard minimisation algorithms, (ii) Obtaining constrained rational filter functions efficiently, and (iii) Improving existing rational filter functions algorithmically. Using our new rational filter functions, FEAST requires up to one quarter fewer iterations on average compared to state-of-art rational filter functions.
Victor Bonney: the gynaecological surgeon of the twentieth century

exercise in excessive regulation based on overly abstracted scientific norms. To counter this, Warren ends with a call for a reconstituted coalition of science and public activism. In this sense Brush with death participates in the history it chronicles: a book written with a rare combination of scholarly rigour and passionate public concern, it provides an intelligent and provocative platform on which to rethink our place in our leaden world.
Cost-based pricing of transportation services in a wholesaler–carrier relationship: an MS Excel spreadsheet decision tool

The purpose of this paper is to describe the development and application of a valuable decision support tool to ensure appropriate pricing of transportation services in the wholesale grocery industry. The impetus for the development of this tool was the recognition that enterprise resource planning systems typically lack data on transportation issues, which means that cost-based pricing is difficult, if not impossible. To address this problem, an MS Excel spreadsheet was developed as a measurement tool over a period of 9 years in close co-operation with providers and buyers of transportation services in Norway. All cost drivers, including loading time, waiting time, speed etc. are included. This paper explains the components of the measurement tool and provides examples of its application. The study concludes that detailed cost analysis and a continuous focus on productivity and risk factors can generate mutually beneficial transportation arrangements between shippers and carriers.
High intensity aerobic interval exercise is superior to moderate intensity exercise for increasing aerobic capacity in patients with coronary artery disease

Background Increased aerobic exercise capacity appears to reduce both all-cause mortality and cardiovascular disease mortality. Physical exercise to improve peak oxygen uptake (VO2peak) is thus strongly recommended, however evidence regarding the most efficient training intensity for patients with coronary artery disease (CAD) is still lacking. The purpose of this randomized study was therefore to assess the effects of high intensity aerobic interval exercise compared to moderate intensity exercise, representing the same total training load, for increasing VO2peak in stable CAD-patients. Methods Twenty-one stable CAD-patients were randomized to supervised treadmill walking at either high intensity (80–90% of VO2peak) or moderate intensity (50–60% of VO2peak) three times a week for 10 weeks. Results After training VO2peak increased by 17.9% (P = 0.012) in the high intensity group and 7.9% (P = 0.038) in the moderate intensity group. The training-induced adaptation was significantly higher in the high intensity group (P = 0.011). Conclusions High intensity aerobic interval exercise is superior to moderate exercise for increasing VO2peak in stable CAD-patients. As VO2peak seems to reflect a continuum between health and cardiovascular disease and death, the present data may be useful in designing effective training programmes for improved health in the future.
New Nordic Nutrition Recommendations are here

Nordic countries have a long tradition of developing joint nutrition recommendations. The latest recommendations, issued on 3 October 2013 (called the Nordic Nutrition Recommendations, NNRs, 2012) are already in their fifth edition. The first NNRs were released in 1980 and thereafter a new edition has been issued every eight years. While the 1996 edition was published in Swedish, the two more recent recommendations have can be read in English. This reflects a recognition that the scientific basis for nutrition recommendations is not limited to specific countries, but should be of interest to a wider group of experts and decision makers. (Published: 3 October 2013) Citation: Food & Nutrition Research 2013. 57 : 22903 - http://dx.doi. org/10.3402/fnr.v57i0. 22903
The pathophysiology of Osgood–Schlatter disease: a magnetic resonance investigation

Osgood–Schlatter disease (OSD) is a well-described clinical condition, although its origin remains controversial. Mechanical, growth or traumatic factors are suggested as causes of this lesion. Thirty-five patients were included in this study. Twenty of them had OSD (study group) and the remaining 15 adolescents constituted the control group. Magnetic resonance imaging of the knees was performed in all patients. The distance between the distal pole of the patella and the proximal margin of patellar tendon attachment to the tibial apophysis (A), the distance between the distal pole of the patella and the tibial tubercle epiphysis (B), the distance between the proximal margin of the patellar tendon attachment to the tibia and the tibial tubercle epiphysis (C) and the distance between the knee joint level and the tibial tubercle epiphysis (D) were measured. The ratio of the distance between the distal pole of the patella and the proximal margin of the patellar tendon attachment to the tibia to the distance between the distal pole of the patella and the tibial tubercle epiphysis (A : B) was lower in the study group. The ratio of the distance between the proximal margin of the patellar tendon attachment point to the tibia and the tibial tubercle epiphysis to the distance between the knee joint level and the tibial tubercle epiphysis (C : D) was higher in the control group. We conclude that if the patellar tendon attaches more proximally and in a broader area to the tibia, this might probably cause OSD.
Antioxidant Quinonemethide Triterpenes from Salacia campestris

A new quinonemethide triterpene named as salacin, has been isolated from the root bark of Salacia campestris in addition to the known pristimerin, maytenin, 20α‐hydroxymaytenin, and netzahualcoyene. Salacin was identified on the basis of NMR‐spectral and mass spectrometric analysis. The free‐radical scavenging activities of the quinonemethide triterpenes salacin (1), pristimerin (2), maytenin (3), 20α‐hydroxymaytenin (4), and netzahualcoyene (5) towards DPPH have been evaluated and showed absorbance variation (ΔA) of 19, 20, 39, 28, 55, and 10%, respectively, having rutin (74% at 50 μM) and BHT (7% at 50 μM) as standard compounds.
A novel bound form of plant invertase in rice suspension cells

A novel alkaline bound invertase (ITab) was purified 116 fold from crude extract of rice suspension cells (Oryza sativa L. cv. Tainong 67). The enzyme can be released by treating the cell wall and membrane fragments with 1.0 M NaCl and purified to homogeneity through the steps of ammonium sulfate precipitation, Con A-Sepharose affinity (non-retained), Sepharose CL-6B, and DEAE-Sepharose chromatographies. The FPLC and SDS-PAGE analy- ses revealed ITab to have a native molecular mass of about 250 kDa, and it may therefore be homotetramer com- posed of subunit with a mass of 60 kDa. Isoelectric focusing analysis indicated that the pI value was 4.7. The optimum pH was 7.6 and the optimum temperature was 40-50°C. ITab can hydrolyze sucrose and raffinose, but not maltose. The enzyme did not have affinity toward Con A. So it is not a glycoprotein. The Km for sucrose was 15.28 mM. Fructose and glucose were inhibitors. The enzyme was activated by additional protein such as bovine serum albumin. Tris, metal ions, and thiol reagents inhibited the enzyme activity, but activity could be restored with DTT. It is suggested that sulfhydryl-group(s) exist either in the active site or nearly active site.
Source position estimation using radial basis functions

The problem of bearing estimation using radar focal plane arrays is addressed. Motivated by a requirement for a compact integrated solution in the sensor focal plane, a basis function approach is adopted. The development of a solution that is robust to sensor noise leads to a ridge regression-type estimate for the model parameters. The approach is assessed using radially symmetric kernel functions on simulated radar data.
Wavelet Estimation of a Density in a GARCH-type Model

We consider the GARCH-type model: S = σ2 Z, where σ2 and Z are independent random variables. The density of σ2 is unknown whereas the one of Z is known. We want to estimate the density of σ2 from n observations of S under some dependence assumption (the exponentially strongly mixing dependence). Adopting the wavelet methodology, we construct a nonadaptive estimator based on projections and an adaptive estimator based on the hard thresholding rule. Taking the mean integrated squared error over Besov balls, we prove that the adaptive one attains a sharp rate of convergence.
Phenotypic and Genotypic Detection of AmpC Enzymes in Clinical Isolates of Escherichia coli and Klebsiella pneumoniae

Background: AmpC β-lactamase enzymes cause multi-drug resistance. Aim and Objectives: The purpose of this study is detection of AmpC enzymes in the isolated strains of E. coli and K. pneumoniae in three educational hospitals in Hamadan (Iran). Materials and Methods: One hundred and forty strains of E. coli and K. pneumoniae were isolated from the hospitals in Hamadan from March to September 2015. To detection of phenotypic AmpC activity, the AmpC detection disks were used. To detect genes encoding for AmpC PCR method was used. Results: Sixty eight isolates (48.5%) were resistant to third generation cephalosporin and of these 61 (43.5%) isolates had MIC 3 8 μg/mL to cefoxitin. All 68 isolates were analyzed by AmpC detection disks, of which 10 (7.14%) isolates were AmpCβ-lactamase producers. By PCR method, 24 (35.2%) isolates had cit and 48 (70.5%) were positive for fox, 42 (61.7%) for ebc, 46 (67.6%) for mox genes. None of the dha and acc genes were identified. Conclusion: High resistance to cephalosporins has been observed among the clinical isolates. Due to the possibility of plasmid transferring of ampC genes between bacterial, changing consumption patterns of antibiotics and the treatment protocols is necessary.
Modeling Derivational Morphology in Ukrainian

We report on a study applying compositional distributional semantic models (CDSMs) to a set of Ukrainian derivational patterns. Ukrainian is an interesting language as it is morphologically rich, and low-resource. Our study aims at resolving inconsistent results from previous studies which employed CDSMs for derivation; we provide evidence for a cross-lingual advantage of CBOW over NMF representations, as well as a simple additive over a lexical function model. In addition, we present two case studies in which we test the capabilities of CDSMs to deal with pattern-level ambiguity and apply the same CDSMs to inﬂectional patterns.
The terminal 5′ phosphate and proximate phosphorothioate promote ligation‐independent cloning

Function studies of many proteins are waited to develop after genome sequencing. High‐throughout technology of gene cloning will strongly promote proteins' function studies. Here we describe a ligation‐independent cloning (LIC) method, which is based on the amplification of target gene and linear vector by PCR using phosphorothioate‐modified primers and the digestion of PCR products by λ exonuclease. The phosphorothioate inhibits the digestion and results in the generation of 3′ overhangs, which are designed to form complementary double‐stranded DNA between target gene and linear vector. We compared our phosphorothioate primer cloning methods with several LIC methods, including dU primer cloning, hybridization cloning, T4 DNA polymerase cloning, and in vivo recombination cloning. The cloning efficiency of these LIC methods are as follows: phosphorothioate primer cloning > dU primer cloning > hybridization cloning > T4 DNA polymerase cloning >> in vivo recombination cloning. Our result shows that the 3′ overhangs is a better cohesive end for LIC than 5′ overhang and the existence of 5′phosphate promotes DNA repair in Escherichia coli, resulting in the improvement of cloning efficiency of LIC. We succeeded in constructing 156 expression plasmids of Aeropyrum pernix genes within a week using our method.
Winding loss mechanism analysis and design for new structure high-frequency gapped inductor

Winding eddy current loss mechanism of high-frequency gapped inductor is studied deeply by two-dimensional finite element analysis. It reveals that concentrated distribution of the magnetic field in the winding window due to the air gap obviously leads to higher flux strength and then higher winding eddy current loss. Based on the analysis, a new simple inductor structure is proposed to make the field in the winding window more uniform by introducing a low permeability magnetic shunt between the gapped core leg and the winding, resulting in a significant winding loss reduction. Moreover, field analysis and design for the new structure are also performed.
A Fast and Power-Efficient Memory-Centric Architecture for Affine Computation

Affine computation is an important part in many vision applications. It is characterized by intensive computation and dependence of cascade memory access. This brief first implements operation fusion based on the data patterns to break the cascade dependence of memory access, and perform memory partitioning for memory-centric optimization to enhance data throughput and data reuse. Then, based on the memory-centric optimization, this brief proposes an affine computation architecture, using specialized pipeline design, which greatly improves computing efficiency. Experiments show that this work achieves higher performance on computing speed and power efficiency when compared with state-of-the-art methods.
IMPACT OF EMPLOYEE ENGAGEMENT ON ORGANIZATIONAL COMMITTMENT IN NATIONAL INSTITUTIONS OF HIGHER LEARNING IN ZIMBABWE

This paper is a presentation of findings of a research carried out to explore the impact of employee engagement on organisational commitment among workers at national higher education institutes (HEI) in Zimbabwe. The research methodology employed an explanatory-descriptive survey design. The respondents were drawn from a stratified random sample of 142 employees from three universities. Employee engagement was measured using the Gallup Worker Audit (GWA) while organisational commitment was measured using the Organisational Commitment Questionnaire. Data were analysed statistically and correlations made between employee engagement and organisational commitment. Results of the study revealed that only 33.8% of the employees were actively engaged while the remaining 66.2 % showed low levels of engagement. The findings also indicated that there is a positive correlation (r = .607, p <.05) between employee
Preferences of Micro-insurance products: Evidence from the mutual assistance fund in Vietnam

This study investigates preferences of clients for microinsurance products using a case study from the Mutual Assistance Fund (MAF), the pioneer microinsurance provider in Vietnam. The study aims to contribute to improving the ability of the young microinsurance industry in Vietnam to meet the needs of its clients, which in turn, will enhance its efficiency, effectiveness and sustainability. In addition, the study examines determinants of microinsurance and identifies potential gateways for microinsurance to serve the uninsured poor in the population. Our results reveal that the current premiums offered by the MAF seem too low and that they have no significant effect to the preferences of clients over product attributes. In the same line with Tran and Yun (2004), we found that clients are willing to pay higher premium in order to receive a higher level of benefit. In addition, the main factors that significantly affect product preferences are experiences in insurance, mathematical ability and attitude towards risk.
Extreme Value Theory based Decision Directed OFDM Channel Tracking

Decision directed channel tracking (DDCT) at high fade rates in OFDM based systems is addressed in this paper. Channel estimation in DDCT can be formulated as a linear errors-in-variables regression problem. While most of the errors in the regression matrix (equalization errors) are Gaussian in nature, few of the detected symbols can have high error due to the frequency and time selective fading. These poor symbol decisions behave like outliers in the regression matrix and give rise to contaminated Gaussian noise distributions. Classical estimators like total least squares (TLS) and the expectation-maximization (EM) based estimators exhibit poor performance in the presence of such outliers. We propose the Huber's M (HM) estimator and an extreme value theory (EVT) based M estimator for the DDCT problem. The proposed HM and EVT-HM estimators are robust to outliers and have an efficiency greater than 95% in purely Gaussian noise. The error rate performance of the proposed HM and EVT-HM estimators are compared with that of the TLS estimator, and the EM based estimator proposed in [4].