Miracle-dz/UniFAR-FTUs huggingface dataset:
PEDro. A database of randomized trials and systematic reviews in physiotherapy.

This paper describes PEDro, the Physiotherapy Evidence Database. PEDro is a web-based database of randomized controlled trials and systematic reviews in physiotherapy. It can be accessed free of charge at http://ptwww.cchs. usyd.edu. au/pedro. The database contains bibliographic details and abstracts of most English-language randomized trials and systematic reviews in physiotherapy, and of many trials and reviews in other languages. Trials on the database are rated on the basis of their methodological quality so that users of the database can quickly identify trials of high quality. Trials and systematic reviews are extensively indexed to facilitate searching. PEDro provides an important information resource to support evidence-based clinical practice.
Development of large aperture, high-frequency piezo-electric transducers for photoacoustic imaging

This paper presents the development of focused single element ultrasound transducers for photoacoustics. Two transducer technologies using 36° rotated Y-cut LiNbO3 have been implemented and compared, namely a LiNbO3 crystal bonded to a glass lens and a shaped piezo-composite. The 50MHz transducer design with an acceptance angle greater than 60° has been optimized by analytical and finite element simulation. One transducer of each technology was developed. A relative bandwidth of 70% and 133% was reached with the self-focused transducer and the lens-focused transducer, respectively. The self-focused transducer has a higher sensitivity compared to the lens-focused transducer, with a 4.7dB gain. Results suggest that the self-focusing technology can be further improved to develop high sensitivity transducers with broader bandwidth.
Antioxidant impregnated ultra‐high molecular weight polyethylene wear debris particles display increased bone remodeling and a superior osteogenic:osteolytic profile vs. conventional UHMWPE particles in a murine calvaria model

Periprosthetic osteolysis remains a major limitation of long‐term successful total hip replacements with ultra‐high molecular weight polyethylene (UHMWPE) bearings. As intra and extracellular reactive oxygen species are know to contribute to wear debris‐induced osteoclastic bone resorption and decreased osteoblastic bone formation, antioxidant doped UHMWPE has emerged as an approach to reduce the osteolytic potential of wear debris and maintain coupled bone remodeling. To test this hypothesis in vivo, we evaluated the effects of crosslinked UHMWPE wear debris particles (AltrX™), versus similar wear particles made from COVERNOX™ containing UHMWPE (AOX™), in an established murine calvaria model. Eight‐week‐old female C57B/6 mice (n = 10/Group) received a pre‐op micro‐CT scan prior to surgical implantation of the UHMWPE particles (2mg), or surgery without particles (sham). Dynamic labeling was performed by intraperitoneal injection of calcein on day 7 and alizarin on day 9, and the calvaria were harvested for micro‐CT and histology on day 10. Surprisingly, we found that AOX particles induced significantly more bone resorption (1.72‐fold) and osteoclast numbers (1.99‐fold) vs. AltrX (p < 0.001). However, AOX also significantly induced 1.64‐fold more new bone formation vs. AltrX (p < 0.01). Moreover, while the osteolytic:osteogenic ratio of both particles was very close to 1.0, which is indicative of coupled remodeling, AOX was more osteogenic (Slope = 1.13 ± 0.10 vs. 0.97 ± 0.10). Histomorphometry of the metabolically labeled undecalcified calvaria revealed a consistent trend of greater MAR in AOX vs. AltrX. Collectively, these results demonstrate that anti‐oxidant impregnated UHMWPE particles have decreased osteolytic potential due to their increased osteogenic properties that support coupled bone remodeling. © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 34:845–851, 2016.
Stress Situations of Daily Living in Patients with Obsessive—Compulsive Disorder: A Retrospective Case Note Study

About 40% of patients with obsessive–compulsive disorder (OCD) are said to have treatment-refractory symptoms and chronic course of illness in spite of cognitive-behavior therapy and pharmacotherapy. The present purpose was to investigate factors relevant to OCD patients' chronic course and disturbed daily functions in view of human basic needs based on Maslow's hierarchy of five basic needs. Case notes of 101 outpatients with OCD (47 men and 54 women who were 18 to 55 years old) and seen on a psychiatry unit of a general hospital were studied to explore their stressful situations and identify thwarted basic needs. 84 of the 101 patients had Love Needs, and Esteem Needs (n = 47) and Safety Needs (n = 45) were next. The Poor-functioning group mainly had histories with problems of Safety Needs (70.8%), while the Good-functioning group tended to mainly have problems of Esteem Needs (51.5%) rather than Safety Needs (33.3%). 57 patients (23 men and 34 women) who were treated for more than three months were divided into two groups according to their Global Assessment of Functioning score at the final assessment (cut-off point: 61); patients in the Good-functioning group tended to have problems of higher needs.
Adoptees’ curiosity and information-seeking about birth parents in emerging adulthood

The Adoption Curiosity Pathway (ACP) model was used to test the potential mediating effect of curiosity on adoption information-seeking in a sample of 143 emerging adult adoptees (mean age = 25.0 years) who were adopted as infants within the United States by parents of the same race. Adoptees were interviewed about their intentions and actions taken to gather new information about their birth mothers and fathers. As expected, level of curiosity was positively associated with information-seeking behavior. Moreover, level of curiosity was influenced by adoptees’ perceptions of barriers and facilitators toward information-seeking. In fact, curiosity partially mediated the impact of internal and external barriers on information-seeking about birth mothers. Curiosity fully mediated the impact of external barriers and partially mediated external facilitators on birth father information-seeking. This study provides important support for the ACP, which describes context, motivation, and behavior relating to seeking new adoption-related information.
Embedded purification for electron beam induced Pt deposition using MeCpPtMe3

Two different room-temperature processes for the electron beam induced deposition of high purity platinum (Pt), using the standard MeCpPtMe3 precursor and oxygen for purification, have been investigated. The first process is a sequential method, which uses two independent gas injector systems (GIS) in order to perform a standard Pt deposition, followed by an e-beam post-irradiation under oxygen flux. The second process is a parallel, single-step process that includes a simultaneous flow of both precursor and oxygen, using an add-on device that can be mounted on the standard GIS needle. Both processes are effective in producing high purity Pt depositions close to 100 at%. The first method requires a high current and irradiation dose in the clean-up phase, and provides Pt structures with small voids, a maximum thickness of around 100 nm and resistivity of 88 ± 10 μΩ cm. The second method requires a high oxygen/precursor flux ratio and produces void-free structures with resistivity of 60 ± 5 μΩ cm, only six times the bulk value for Pt. The second method is easier to use and produces a void-free deposition of high purity Pt.
Eléments de mécanique quasi-statique des milieux granulaires mouillés ou secs

1) Presentation generale de la mecanique des milieux granulaires aux petites deformations, puis 2) proposition d'une loi simplifiee permettant de decrire le comportement macroscopique des milieux granulaires. 3) proposition d'une vue du passage micro-macro et de l'influence des fluctuations statistiques, en maintenant le lien avec certains comportements experimentaux (Tap-tap, comportement cyclique,.)
Methotrexate in pediatric plaque-type psoriasis: Long-term daily clinical practice results from the Child-CAPTURE registry

Abstract Background: Evidence on effectiveness and safety of methotrexate (MTX) in pediatric psoriasis is scarce. Objectives: To study the effectiveness and safety of MTX in pediatric plaque-type psoriasis and its influence on quality of life (Qol) in daily clinical practice. Methods: Subset analysis of prospectively collected data extracted from the Child-CAPTURE registry, a single center, longitudinal, long-term, observational daily practice cohort of pediatric psoriasis patients. A maximum dose between 0.14 and 0.63 mg/kg once weekly was prescribed in 25 children. Primary endpoints were percentages of patients with ≥ 75% improvement in the Psoriasis Area and Severity Index (PASI) at week 12 and 24. Results: PASI75 was achieved in 4.3% and 33.3% of patients at week 12 and 24, whereas 40% and 28.6% reached PASI 75 at week 36 and 48. Median PASI and body surface area decreased from 10.0 (range 3.8–42.4) and 11.0 (range 3.5–72.0) at baseline to 4.3 (range 0–19.8) and 2.6 (range 0.0–39.6) at week 24, respectively. Physician Global Assessment improved significantly from 3.0 to 1.2 at week 24. A significant decrease in Children’s Dermatology Life Quality Index from 9.0 to 3.8 at week 24 was found. Most reported adverse events were severe nausea (n = 5), infections requiring antibiotics (n = 5) and tiredness (n = 4). Conclusions: MTX shows a positive effect on PASI scores, improves Qol and has a reasonable safety profile.
Grasping by wrapping: Mechanical design and evaluation

This paper presents an analysis of the design and operation of a non-articulated robotic hand, inspired by the multilayered structure. The hand is made of a non-stretchable thin film, the two ends of which are attached to a soft substrate, forming an enclosed wrinkled shape. When the substrate is elongated, the morphology of the hand changes varied, resulting in a “wrapping” form around the grasped object. This design is applicable to a wide range of objects that can be grasped by the robotic hand. The smallest and biggest sizes of the grasped object are determined by the morphological computation of the film during design of the hand. This design also reduces the uncertainty of position between the hand and the object; i.e., stable grasping can be maintained as long as the object fits within the enclosed form of the hand. A mechanism controlling the morphology of the film using only one actuator, and for grasping food products such as fruits, is proposed. Preliminary results show the potential of the hand's morphology in the design of soft robotic mechanisms.
Influence of membrane properties on spike synchronization in neurons: theory and experiments

In the brain spike synchronization in neurons is involved in information transfer and certain forms of dysfunction. The theory of random point processes was used to relate the statistical properties of input point processes to synchronization between firing in neurons viewed as threshold devices. Derived analytical relations describe normalized synchronization in the case of shared input with balanced excitation and inhibition. For neuronal models with unbalanced shared input and spike generating Hodgkin–Huxley type conductances, the theory satisfactorily describes the temporal dependence of spike synchronization on the delay between spikes. Computer generated stochastic stimulus current was used to stimulate motoneurons in turtle spinal cord slices. Theory was able to approximate the temporal dependence of spike synchronization on the delay between spikes when the membrane time constant and the relative spike threshold measured were used in calculations. In agreement with the theoretical prediction, normalized spike synchrony was reduced when the threshold for spike generation was lowered by injection of steady depolarizing bias current. In spinal motoneurons the relative spike threshold can be lowered by a persistent inward current facilitated by activation of certain metabotropic transmitter receptors. After induction of this inward current spike synchronization was reduced several times. It is suggested that downregulation of the persistent inward current in motoneurons by disruption of brainstem modulatory systems, as in Parkinson disease, can facilitate tremor due to the increased synchrony between motoneurons.
Evaluation of QoS in data mobile network for vital signs transmission

The quality of pre-hospital care and timely coordination of the stakeholders in the public health network, play a very important role maintaining the status of a patient. The integration of technology in emergency scenarios is proposed as a tool to improve response times, monitor patient status and even perform video-consultations between the site of the incident and medical personnel located in certain clinics. The parameters of QoS (maximum latency and percentage of packet loss) that the network must provide to the different telemedicine services, as well as the logical infrastructure, physical infrastructure and network devices that comprise it were also defined. The performance of the LTE network for the uplink data flow was evaluated through NS-3 software. The results show that the network performance decreases when the traffic generated by other users increase or by increasing the bit rate of the information from ambulances. Additionally, it showed that the network performance can improve substantially by increasing radio resources or bandwidth channel of the LTE network.
Percutaneous Phenol Block of the Upper Thoracic Sympathetic Chain with Computed Tomography Guidance

Twenty-one percutaneous neurolyses of the upper thoracic sympathetic chain were performed in 12 patients with CT guidance by a single injection of 1 to 3 ml of phenol at the level of Th3. Results were assessed after a follow-up period varying from 4 to 33 months. Three patients with hyperhidrosis had immediate and complete disappearance of symptoms, but only one patient remained dry. In 7/14 procedures done for Raynaud's disease symptoms disappeared or diminished. These long term results are competitive with surgery. Three transitory Horner syndromes and one pneumothorax occurred.
Flight control for hypersonic vehicle based on quasi-continuous integral high-order sliding mode

This paper first applied integral sliding mode concept to design of nonlinear robust controller for hypersonic vehicle model which is nonlinear, multivariable, and includes uncertain parameters. Firstly, the multi-input and multi-output (MIMO) quasi-continuous integral high-order sliding mode controller is proposed to track the responses of the vehicle to a step change in altitude and velocity. Furthermore, based on the simulation results, the virtual control is introduced into the design of fourth-order velocity and fifth-order altitude quasi-continuous integral sliding mode controller in order to reduce the control chattering. The arbitrary order robust sliding mode differentiator is used to calculate the missing differential which is used in the design of controller. Finally, Simulation results show that the proposed methodology guarantees the whole robustness of the system throughout an entire response of the system and achieves excellent tracking performances in spite of parameter uncertainties.
Comparison of different doses of ε-aminocaproic acid in children for tetralogy of Fallot surgery: clinical efficacy and safety.

OBJECTIVE The purpose of this study was to compare 2 different doses of ε-aminocaproic acid (EACA) and assess their relative efficacy and safety in children undergoing corrective surgery for tetralogy of Fallot (TOF). DESIGN A prospective, randomized, controlled study. SETTING A tertiary care center. PARTICIPANTS One hundred twenty children undergoing corrective surgery for TOF using cardiopulmonary bypass (CPB). INTERVENTIONS Group 1 received 100 mg/kg of EACA after induction, upon initiation of CPB, and after protamine. Group 2 received 75 mg/kg of EACA after induction, followed by a maintenance infusion of 75 mg/kg/h until chest closure, and an additional 75 mg/kg upon initiation of CPB. Group 3 did not receive any antifibrinolytic agent or placebo. MEASUREMENT AND MAIN RESULTS Cumulative mean blood loss, total packed red blood cells, and fresh frozen plasma requirements were significantly less in group 2 (p ≤ 0.01). There were no significant differences in the total platelet concentrate transfused, re-exploration rate, incidence of renal failure, arrhythmias, neurologic complications, mortality, or length of intensive care unit stay among the 3 groups. The incidences of perioperative ST/T changes and chest closure time were significantly less in group 1 and group 2 (p ≤ 0.01). The duration of mechanical ventilation was significantly less in group 2 (p ≤ 0.01). CONCLUSIONS EACA was effective in reducing the postoperative blood loss and transfusion requirements in children undergoing corrective cardiac surgery on CPB for TOF. The dose regimen of 75 mg/kg after induction, followed by a maintenance infusion of 75 mg/kg/h until chest closure, and an additional 75 mg/kg upon initiation of CPB were more effective.
Visual objects categorization using dense EEG: A preliminary study

The ability of the brain to categorize or group visual stimuli based on common features is a fundamental principle of cognition. This categorization is very fast and occurs in few millisecond time scales. Due to the excellent temporal resolution, on the order of millisecond, of the Electroencephalogram (EEG), categorization of images containing visual objects can be effectively recognized using Event Related Potentials (ERPs) derived from EEG signals recorded when images are presented in screen in front of the subjects. The aiming of this paper is to show preliminary results about how the processing of objects in the human brain unfolds in time using dense EEG. In this paper, we show a time-resolved view of the human brain for objects and animals. We showed a difference between the spatiotemporal behaviors of ERP signals recorded in two conditions: objects and animals. Using The Support Vector Machine (SVM) classifier, results showed a high performance of the dense EEGs to differentiate between objects and animals.
On the use of IRC channels by developers of the GNOME GTK + open source project

Developers of open source projects are distributed across the world. They rely on email, mailing lists, instant messaging and more recently IRC channels to communicate. Most of the studies thus far focus on the use of mailing lists by OSS developers, however, an increasing number of open source projects are using IRC channels to hold developer meetings. In many cases, these IRC meetings supplement mailing lists discussions and serve as a place where developers can settle discrepancies and get quick feedback. In this paper, we mine the #gtk-devel IRC channel and study the usage of the IRC channel by the GNOME GTK+ core maintainers. We look at three different dimensions: the length of the meetings, the number of participants attending the meetings and the activity of these participants. Our findings show that IRC channels are gaining popularity among open source developers and maintainers: IRC meetings are increasing in length, have increasing attendance levels, and the participants actively contribute to the meetings. To the best of our knowledge, this is the first study on the use of IRC channels by OSS developers.
Antibody‐Based Detection of Acid‐Shocked, Acid-Adapted, and Apple Juice-Incubated Escherichia coli O157:H7

Abstract Sandwich enzyme‐linked immunosorbent assays (sELISA) allow for rapid detection of Escherichia coli (E. coli) O157:H7. Acidic conditions similar to those in certain foods and juices may reduce the ability to detect E. coli O157:H7. Growth of E. coli O157:H7 at pH 4 compared to pH 5–7 reduced fluorescent signal at the lower bacterial concentrations without altering the range of detection. Both acid‐adaptation and a subsequent pH 7 incubation reversed sensitivity. Incubation in apple juice was not deleterious to sELISA detection. Exposure to acidic conditions can cause a small reduction in sELISA sensitivity used to detect E. coli O157:H7.
Fragmentation cross sections of relativistic 8436Kr and 10947Ag nuclei in targets from hydrogen to lead.

With the addition of krypton and silver projectiles we have extended our previous studies of the fragmentation of heavy relativistic nuclei in targets ranging in mass from hydrogen to lead. These projectiles were studied at a number of discrete energies between 450 and 1500A MeV. The total and partial charge-changing cross sections were determined for each energy, target, and projectile, and the values compared with previous predictions. A new parametrization of the dependence of the total charge-changing cross sections on the target and projectile is introduced, based on nuclear charge radii derived from electron scattering. We have also parametrized the energy dependence of the total cross sections over the range of energies studied. New parameters were found for a previous representation of the partial charge-changing cross sections in hydrogen and a new parametrization has been introduced for the nonhydrogen targets. The evidence that limiting fragmentation has been attained for these relatively light projectile nuclei at Bevalac energies is shown to be inconclusive, and further measurements at higher energies will be needed to address this question.
Complete mitochondrial genome of Gnathopogon taeniellus (Cypriniformes: Cyprinidae)

Abstract The complete mitochondrial genome of Gnathopogon taeniellus was first determined in this study. It is 16,596 bp in length, contains 13 protein-coding genes, 2 rRNA genes, 22 tRNA genes and one control region in the typical vertebrate gene order and transcriptional direction. There are total of 29 bp short overlaps and 34 bp non-coding intergenic spacers were found in the mitogenome. Overall nucleotide base composition of light strand is 29.3% A, 25.8% C, 17.9% G and 27.0% T. Two start codons (ATG and GTG) and two stop codons (TAG and TAA/T) were used in the protein-coding genes. The origin of light strand replication (OL) was identified between tRNAAsn and tRNACys genes and could fold a hairpin structure. The nucleotide composition of control region is 31.8% A, 20.9% C, 14.0% G and 33.3% T.
Turizm Lisans Öğrencilerinin Turizm Sektöründe Çalışma Eğilimleri Üzerine Bir Araştırma

Bu arastirmanin temel amaci, turizm lisans ogrencilerinin turizm sektorunde calisma egilimlerine (TSCE) yonelik tutumlarini ortaya koymaktir. Calismada tabakali ornekleme yontemi kullanilmistir. Bu dogrultuda Turkiye’nin her bolgesinden en cok ogrencisi olan bir fakulte veya yuksekokul secilerek, ogrenci sayisinin buyuklugu ile dogru orantili orneklem alinmistir. Anket yoluyla 800 katilimcidan elde edilen verilerin analizi icin t-testi ve tek yonlu ANOVA kullanilmistir. Arastirmada kadinlarin erkeklere, okudugu bolumu isteyerek secenlerin istemeyerek secenlere kiyasla TSCE’ne yonelik tutumlari, anlamli bir sekilde yuksek bulunmustur. Staj/mesleki deneyimi olmayanlarin, staj/mesleki deneyimi olan katilimcilara kiyasla TSCE’ne yonelik tutumlarinin anlamli bir sekilde daha yuksek oldugu tespit edilmistir.