Miracle-dz/UniFAR-FTUs huggingface dataset:
Prevalence of IgA-antiendomysial antibody in a patient cohort with idiopathic low bone mineral density.

AIM To investigate the frequency of serum IgA-antiendomysial antibody positivity in patients with low bone mineral density and to assess the risk group for screening of celiac disease. METHODS One hundred and thirty-five patients (14 male, 121 female) with idiopathic low bone mineral density were evaluated. The median age was 57.2 years (24-81). Antiendomysial antibody was determined by the immunofluorescence method using a commercial kit (INOVA Diagnostics Inc., CA, USA), which employs a 5 microm thin cryostat section of monkey esophagus as a substrate. RESULTS Of the 135 patients evaluated, 13 were found to have positive IgA antiendomysial antibody test (9.6%) response. None of the patients had IgA deficiency. Endoscopic appearance and histological examination were normal in all of these patients. Seropositive patients had significantly lower age (48.9 +/- 4.3 vs 59.2 +/- 6.2, P < 0.05), higher ratio of male gender (61.5% vs 4.9%, P < 0.01) and pre-menopausal status (8.7% vs 1.3%, P < 0.01). Lumbar spine and femoral neck z-scores, but not t-scores were significantly lower in seropositive patients. Seropositive patients had lower serum 25 (OH) vitamin D, calcium and higher serum parathormone levels than seronegative patients. CONCLUSION The screening of celiac disease in idiopathic osteoporosis should be restricted to patients without classical risk factors (younger, pre-menopausal, male gender) for osteoporosis. Bone mineral density measurements using z-scores should be considered for identifying risk groups for celiac disease.
Periventricular heterotopia in 6 q terminal deletion syndrome : role of the C 6 orf 70 gene

Periventricular heterotopia in 6q terminal deletion syndrome: role of the C6orf70 gene Valerio Conti,* Aurelie Carabalona,* Emilie Pallesi-Pocachard, Elena Parrini, Richard J. Leventer, Emmanuelle Buhler, George McGillivray, François J. Michel, Pasquale Striano, Davide Mei, Françoise Watrin, Stefano Lise, Alistair T. Pagnamenta, Jenny C. Taylor, Usha Kini, Jill Clayton-Smith, Francesca Novara, Orsetta Zuffardi, William B. Dobyns, Ingrid E. Scheffer, Stephen P. Robertson, Samuel F. Berkovic, Alfonso Represa, David A. Keays, Carlos Cardoso and Renzo Guerrini
Biomimetic approach to cardiac tissue engineering

Here, we review an approach to tissue engineering of functional myocardium that is biomimetic in nature, as it involves the use of culture systems designed to recapitulate some aspects of the actual in vivo environment. To mimic the capillary network, subpopulations of neonatal rat heart cells were cultured on a highly porous elastomer scaffold with a parallel array of channels perfused with culture medium. To mimic oxygen supply by haemoglobin, the culture medium was supplemented with a perfluorocarbon (PFC) emulsion. Constructs cultivated in the presence of PFC contained higher amounts of DNA and cardiac markers and had significantly better contractile properties than control constructs cultured without PFC. To induce synchronous contractions of cultured constructs, electrical signals mimicking those in native heart were applied. Over only 8 days of cultivation, electrical stimulation induced cell alignment and coupling, markedly increased the amplitude of synchronous construct contractions and resulted in a remarkable level of ultrastructural organization. The biomimetic approach is discussed in the overall context of cardiac tissue engineering, and the possibility to engineer functional human cardiac grafts based on human stem cells.
Schema Design and Normalization Algorithm for XML Databases Model

In this paper we study the problem of schema design and normalization in XML databases model. We show that, like relational databases, XML documents may contain redundant information, and this redundancy may cause update anomalies. Furthermore, such problems are caused by certain functional dependencies among paths in the document. Based on our research works, in which we presented the functional dependencies and normal forms of XML Schema, we present the decomposition algorithm for converting any XML Schema into normalized one, that satisfies X-BCNF.
Do additional views improve the diagnostic performance of cervical spine radiography in pediatric trauma?

OBJECTIVE The aims of this study were to measure the diagnostic performances of lateral views alone and multiple radiographic views of the cervical spine in comparison with MDCT scans in pediatric trauma and to determine whether evaluation of additional views, in relation to lateral views alone, improves the performance of radiography. MATERIALS AND METHODS Retrospective analysis of cervical spine radiographs of 234 pediatric patients (age range, 3 months-17 years 11 months) who had been seen in our pediatric emergency department during the period of 2000-2005 for evaluation after acute trauma was performed. All patients underwent cervical spine MDCT examination at the same presentation. Radiographs were evaluated for the presence of fractures, subluxations, and dislocations. Radiographic abnormalities were correlated to findings on MDCT, which was used as the reference standard. RESULTS Twenty-two patients had positive findings on CT: Atlantooccipital subluxation/dislocation was seen in one patient; C1 ring fracture, in three patients; C1-C2 rotatory subluxation, in one; C1-C2 subluxation/dislocation, in one; odontoid fracture, in two; vertebral body wedge fracture, in six; posterior arch fracture dislocation, in 10; and spinous process fracture, in none. The lateral view radiograph alone had 73% sensitivity (95% CI, 50-89%) and 92% specificity (95% CI, 87-95%) for cervical spine abnormalities compared with MDCT. The addition of other views did not change the sensitivity of radiography but rather marginally decreased its specificity to 91% (95% CI, 86-94%). CONCLUSION Lateral view radiographs had a borderline acceptable sensitivity to cervical spine abnormalities in pediatric patients compared with MDCT. The addition of other radiographic views did not seem to improve the diagnostic performance of radiography.
Green HRM in Pursuit of Environmentally Sustainable Business

Environmental sustainability is generating increased concern among business executives, governments, consumers, and management scholars. Amidst the stakeholders’ struggle and the challenges and opportunities from environmental concerns, HRM function joins the ongoing discussions and debates. The business domain sees the genesis of Green HRM with the expanding role of the HRM function in pursuit of environmentally sustainable business. Are HRM (or simply, HR) policies and practices getting transformed to incorporate a new way of work for people? The ‘green’ way? In view of this, the paper intends to explain the concept of Green Human Resource Management, the companies’ approach towards green HRM, its advantages, policies and practices. The paper discusses the current trends of green HRM practices in companies based on findings from a few studies, survey reports and secondary data from companies’ web resources. It also brings out the role of HRM function towards creating a ‘green’ culture in companies.
Rumination, heartburn, and daytime gastroesophageal reflux. A case study with mechanisms defined and successfully treated with biofeedback therapy.

A 31-year-old man with a 19-year history of rumination developed frequent episodes of heartburn and regurgitation associated with acid gastroesophageal reflux that occurred predominantly during the day. This reflux and its attendant symptoms resulted from abdominal muscle contractions at the time of gastroesophageal pressure equilibration (i.e., common cavity phenomena) consistent with the egress of air from the stomach to the esophagus. A voluntary pharyngeal maneuver unassociated with swallowing but simultaneous with the abdominal contraction resulted in a decrease in upper esophageal sphincter pressure. This lowered pressure facilitated acid esophagopharyngeal regurgitation at a velocity of 100 cm/s. Biofeedback therapy directed at relaxing the abdominal muscles during eating and avoiding the pharyngeal maneuver resulted in a decrease in reflux and marked improvement in symptoms.
Bone Morphogenetic Protein Gene Therapy

Study Design. A retrospective analysis of previous BMP gene therapy and general gene therapy publications. Objective. To present the potential role of BMP gene therapy for the induction of osteogenesis and spinal fusion. Summary of Background Data. A variety of viral and non-viral techniques have been utilized to insert foreign transgenes into cells, both in vivo and in vitro. These techniques are now being used to transduce cells with a BMP gene to express significant amounts of BMP. This secreted BMP can subsequently stimulate osteogenesis in a variety of locations, including in the paraspinal regions. Methods. A retrospective analysis of the literature. Results. Direct and ex vivo BMP gene therapy has been shown to successfully promote bone healing and regeneration in a variety of animal models. Long-term and regulated transgene expression are clear advantages of BMP gene delivery, compared to direct BMP application. To date, BMP gene delivery with adenoviral vectors have been the most effective approach for stimulating bone induction in vivo. Conclusions. Although BMP gene therapy techniques have significant potential for the treatment of spine pathology, further preclinical and clinical research and development are required before this technology will have direct clinical applications.
Big Data Privacy Using Fully Homomorphic Non-Deterministic Encryption

Big data is a large amount of digital information. Now days, data security is a challenging issue that touches several areas along with computers and communication. The security of data which stored online has become a main concern. Several attackers play with confidentiality of the user. Cryptography is a approach that provide data security to the user. Despite of huge efforts to protect sensitive data, hackers typically manage to steal it. Computing with encrypted data is strategies for safeguarding confidential data. The partial homomorphic encryption is specialized for only one operation on the encrypted data. For example the Pailliers encryption scheme performs only one mathematical operation on encrypted numerical data and is successful to compute the sum of encrypted values. The Pailliers encryption scheme is unable to do multiple mathematical operations on encrypted numerical data. The proposed encryption algorithm computes more than one mathematical operation on encrypted numerical data thereby further protecting the encrypted sensitive information.
Dual-Mode Dual-Band Filter With Band Notch Structures

A novel approach for designing dual-mode dual-band bandpass filters is proposed and experimentally studied. By embedding a pair of slits in the square patch, the dual-band response is realized and one transmission zero is introduced between the two passbands. Two degenerate modes are achieved by loading with a small square perturbation, which can be placed at the diagonal line. There are three transmission zeros. The slits control the first and third transmission zeros. On the other hand, the right crossed slots control the first and the second transmission zeros.
Managers' Opportunistic Trading of Their Firms' Shares: A Case Study of Executives in the Banking Industry

Providing managers with stock in the firm may help ensure that managers act in the shareholders' interest. The level of managerial stock ownership, however, is not generally controlled by the firm's compensation committee. Rather, managers themselves determine the level of their stock holdings. To date, though, little evidence exists on managers' personal transactions and how these trades affect their overall equity holdings. This analysis provides insight on the trading practices of bank managers. ; I find that managers do not rely solely on the actions of a compensation committee to set their stock holdings. The assumption that managerial stock holdings are determined solely by the firm's compensation committee is shown to be inaccurate. I provide evidence that managerial open market purchases and sales are both primary determinants of the level of managerial stock holdings. I also show that managers alter their holdings in an opportunistic manner. In general, managers alter their stock holdings when their firm's prospects change. Managers consistently take advantage of private firm-specific information, earning positive abnormal returns on open market purchases while avoiding negative abnormal returns by making open market sales. ; Evidence suggests that opportunistic trading is most prevalent among managers who face the greatest exposure to their firm's nonsystematic risk. In general, managers appear to "fine tune" the proportion of their wealth that is sensitive to changes in firm value. In effect, this trading increases the rate of return and reduces the riskiness of holding those shares. This increased return/risk trade-off, available to managers who trade shares in their firms, may help explain why many managers are willing to hold what appears to be an undiversified stake in their firm.
Do the Poor Benefit From More Generous Medicaid Physician Payments?⇤

This paper examines how changes in Medicaid physician payments affect provision of care to both Medicaid patients and the uninsured. I find that payment increases generate an increase in supply of care to Medicaid patients but a more than offsetting decrease in supply to the uninsured. Using survey data, I additionally show that physicians encourage their uninsured patients to enroll in Medicaid. Finally, I demonstrate that when Medicaid eligibility is high, physicians are less likely to substitute between caring for Medicaid patients and treating the uninsured. Because higher eligibility magnifies the Medicaid supply response to a payment change, my results suggest that payment increases should be coupled with eligibility expansions in order to improve access to care among the poor. ⇤I am indebted to my advisers Marianne Bertrand, David Meltzer, Matthew Notowidigdo, and Emily Oster for their generous guidance. I also thank Steven Levitt, Willard Manning, Jessica Pan, Tomas Philipson, Matthew Plosser, Kosali Simon, and Heidi Williams for their helpful comments. Financial support from the Agency for Health Care Research and Quality T32 National Research Service Award Fellowship is gratefully acknowledged. †Booth School of Business, University of Chicago, email: alice.chen@uchicago.edu ‡For most recent version, click here.
The interplay of different types of governance in horizontal cooperations : a view on logistics service providers

Purpose – Over the last decades, horizontal cooperations between logistics service providers (LSPs) have become a well-established organizational form and their use is expected to grow even further in the future. In spite of this increasing importance of horizontal LSP cooperations, little research has been done to reveal how to govern these relationships successfully. Particularly, the role of contractual governance and its interplay with operational governance mechanisms remain to be investigated. The paper aims to discuss these issues. Design/methodology/approach – This research analyzes the influence of contractual governance on the effectiveness of two types of operational governance (a formal and a relational type). It relates contractual governance and operational governance to two major outcome dimensions of horizontal cooperations between LSPs (cooperation-based firm performance and cooperation-based learning) and uses multivariate statistical methods. Findings – The results reveal that contractu.
SUPPLEMENTARY INFORMATION for Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes

Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes Diwakar R. Pattabiraman, Crystal McGirr, Konstantin Shakhbazov, Valerie Barbier, Keerthana Krishnan, Pamela Mukhopadhyay, Paula Hawthorne, Ann Trezise, Jianmin Ding, Sean M Grimmond, Peter Papathanasiou, Warren S. Alexander, Andrew C. Perkins, JeanPierre Levesque, Ingrid G. Winkler, Thomas J. Gonda
Survey on controversies in airway management among anesthesiologists in the UK, Austria and Switzerland.

BACKGROUND While surveys about anesthesia practice appear regularly in the anesthesia literature, they are usually bound to one country. We compared the approach to specific airway management issues among anesthesiologists from three different European countries. METHODS A questionnaire was distributed during the main session of three anesthesia meetings in Austria (A), the UK, and Switzerland (CH). Questions concerned whether anesthesiologists routinely check for risk factors associated with difficult mask ventilation; whether anesthesiologists are used to mask ventilate prior to administering neuromuscular blocking drugs (NMBD); whether anesthesiologists apply cricoid pressure. RESULTS We evaluated 266 questionnaires. No significant differences in the frequency of checking predictors were found, except for "age" (UK: 28%, A: 13%, CH:11%, P=0.01). Fewer anesthesiologists from the UK always check mask ventilation before NMBD (UK: 34%, A: 72%, CH: 67%, P<0.001); but they check mask ventilation more often when risk factors are present (UK: 36%, A: 13%, CH: 20%, P=0.004). Very few anesthesiologists from the UK never apply cricoid pressure (UK: 2%, A: 40%, CH: 49%, P<0.001), but almost all of them apply it in case of rapid sequence intubation (UK: 96%, A: 52%, CH:30%, P<0.001). CONCLUSION Answers from anesthesiologists in the UK differed significantly from those in A and CH. Anesthesiologists in the UK check mask ventilation after induction less frequently, but they check more often when risk factors of difficult mask ventilation are present. Cricoid pressure seems to remain an important part of the rapid sequence induction technique in the UK, whereas anesthesiologists in Austria and Switzerland rely less on this technique.
Motives and Barriers to Cloud ERP Selection for SMEs: A Survey of Value Added Resellers (VAR) Perspectives

Motives and Barriers to Cloud ERP Selection for SMEs: A Survey of Value Added Resellers Perspectives BY Michael Leigh Garverick April 22, 2014 Committee Chair: Dr. Michael J. Gallivan Major Academic Unit: Department of Computer Information Systems Small to Mid-size Enterprises (SMEs) typically are slow/late to adopt new technologies due to a conservative bias, cost factors and possible lack of knowledge. Implementation of a new Enterprise Resource Planning (ERP) system is a major, costly undertaking for a company of any size, especially SMEs, but there is the potential for huge paybacks touted by advantages afforded by the cloud. Cloud based ERP technology for SMEs is relatively new and poses a potential large risk-reward payoff. Given that these SMEs are currently functioning with their existing systems, why would they want to risk switching to "Bleeding Edge" Cloud ERP technology? Prior ERP research has focused primarily on an ERP’s implementation success and the relevant critical success factors (CSFs) important throughout the various stages of an ERP’s lifecycle. The focus of these studies has been on post-selection variables and the success or failure of the ERP’s adoption or implementation. Inherent in these studies are firms who already selected ERP technology which provides no insight into any potential barriers that prevent selection. ERP research in the area of SME cloud/SaaS ERP systems is nascent. This paper adds methodological, empirical and theoretical contributions to this existing stream of research about the motives and barriers in the selection of cloud ERP systems for SME’s. In particular, this research paper proposes to help bridge these gaps by operationalizing and testing Saeed, JuellSkielse, and Uppstrom (2012)’s Unified Framework (UF) of the motives and barriers to the selection of cloud ERP systems. This current study uses Value Added Resellers (VARs) as subjects. They are arguably the most knowledgeable and in the best position to assess both the motives and more importantly barriers since there are in direct contact with the cloud ERP prospective purchasers.
Modelling Perceived Quality in Fruit Products

Abstract Quality is in the eye of the beholder. Therefore, the firm's marketing strategy must be carried out by taking into consideration not only the consumers' objectively measurable needs and expectations but also their subjective perceptions as to what actually constitutes a quality product. Turning to Olson and Jacoby's distinction regarding the difference between a product's intrinsic and extrinsic attributes, the authors performed the estimation of structural equation models in order to assess the contribution of fruit product attributes to the Spanish consumers' perception of quality. In this article, the authors demonstrate that: (a) perceived quality in fruit products is a multidimensional concept depending on both intrinsic and extrinsic attributes; (b) intrinsic attributes exert a greater influence on perceived quality in fruit products than do extrinsic attributes; and (c) a very limited number of attributes (only seven out of twenty) stand out as being statistically significant to the consumers' perception of quality in fruit products. Finally, they provide statistical estimates pertaining to the relative contribution of the most significant intrinsic and extrinsic attributes to perceived quality in fruit products.
Biodegradable polycaprolactone-chitosan three-dimensional scaffolds fabricated by melt stretching and multilayer deposition for bone tissue engineering: assessment of the physical properties and cellular response

Fabrication of polycaprolactone (PCL)-chitosan (CS) three-dimensional (3D) scaffolds using the novel technique of melt stretching and multilayer deposition was introduced. In brief, firstly, the PCL-CS monofilaments containing 0% (pure PCL), 10%, 20% and 30% CS by weight were fabricated by melting and stretching processes. Secondly, the desired multilayer (3D) scaffolds were fabricated by arranging and depositing the filaments. Physical properties of the filaments and the scaffolds were evaluated. MC3T3-E1 cell lines were seeded on the scaffolds to assess their proliferation. A typical micro-groove pattern was found on the surfaces of pure PCL filaments due to stretching. The filaments of PCL-30%CS had the highest tendency of fracture during stretching and could not be used to form the scaffold. Increasing CS proportions tended to reduce the micro-groove pattern, surface roughness, tensile strength and elasticity of the filaments, whilst compressive strength of the PCL-CS scaffolds was not affected. The average pore size and porosity of the scaffolds were 536.90 ± 17.91 µm and 45.99 ± 2.8% respectively. Over 60 days, degradation of the scaffolds gradually increased (p > 0.05). The more CS containing scaffolds were found to increase in water uptake, but decrease in degradation rate. During the culture period, the growth of the cells in PCL-CS groups was significantly higher than in the pure PCL group (p < 0.05). On culture-day 21, the growth in the PCL-20%CS group was significantly higher than the other groups (p < 0.05). In conclusion, the PCL-20%CS scaffolds obtained the optimum results in terms of physical properties and cellular response.