Miracle-dz/UniFAR-FTUs huggingface dataset:
Succinic Dehydrogenase Histochemistry Reveals the Location of the Putative Primary Visual and Auditory Areas within the Dorsal Ventricular Ridge of Sphenodon punctatus

In turtles, crocodilians, lizards and snakes, the dorsal ventricular ridge (DVR) is a nuclear cell mass that contains distinct visual and auditory thalamorecipient cell groups. In the tuatara (Sphenodon punctatus), the DVR is not organized into diverse cell groups but instead possesses a trilaminar cytoarchitecture resembling that characteristic of the telencephalic cortex in reptiles. To determine if visual and auditory fields might also be present in the DVR of Sphenodon punctatus, we used succinic dehydrogenase (SDH) histochemistry, which has been shown to delineate the visual and auditory fields of the DVR in turtles, crocodilians and lizards. We also used acetylcholinesterase (AChE) histochemistry to determine the boundary between the DVR and the basal ganglia in Sphenodon. We found an SDH-rich region in the neuropil ventral to the cell plate of the rostrolateral DVR and a slightly less intense SDH-rich zone in the neuropil deep to the cell plate of the ventromedial DVR. These SDH-rich zones appear to be located at the apical dendrites of the neurons of the adjacent cell plate. These SDH-rich zones were clearly located within the DVR and were distinct from the AChE-rich striatal part of the basal ganglia, which occupied the ventrolateral wall of the telencephalon. Based on findings in other reptiles, it seems likely that the SDH-rich zone in rostrolateral DVR represents the zone of termination of nucleus rotundus visual input to the DVR, whereas the zone in ventromedial DVR represents the zone of termination of nucleus reuniens auditory input. Because a trilaminar DVR such as that in Sphenodon might be the primitive DVR condition for reptiles, our results suggest that the cytoarchitecture of the DVR and the synaptic organization of its thalamic sensory input in the common ancestor of living reptiles might have been much like of the dorsal cortex.
The GOODLY Design Language for MOOD2 Metrics Collection

The GOODLY language can be used to specify the design of applications or libraries built according to the Object Oriented paradigm. It was conceived with the main purpose of facilitating the extraction of MOOD design metrics [Abreu94]. It allows expressing the most relevant design information for that purpose, such as the class structure with corresponding inheritance relations, uses relationships, message exchanges and information hiding. This language, whose syntax and semantics are fully described, is being used in the production of a new generation of the MOODKIT tools that allow the MOOD metrics extraction.
Cognitive therapy for vomit phobia: a case report

The specific phobia of vomiting (also known as emetophobia) is an under-researched area. We present a case report of cognitive therapy treatment for vomit phobia in order to demonstrate the successful implementation of the cognitive techniques proposed by the cognitive models of vomit phobia. The client was a Japanese female living in the UK whose vomit phobia remained after treatment for panic disorder and comorbid depression. The case formulation suggested that the manner in which her fear escalated was similar to the cognitive model of panic disorder. The therapy involved case formulation, attention training, opinion survey and behavioural experiments. These techniques allowed the client to stop her safety-seeking behaviours and adjust her beliefs about vomiting.
Set-membership identification of linear systems with input backlash

In this paper we present a two-stage procedure for deriving parameters bounds of linear systems with input backlash when the output measurement errors are bounded. First, using steady-state input-output data, parameters of the nonlinear dynamic block are tightly bounded. Then, given a suitable PRBS input sequence we evaluate tight bounds on the unmeasurable inner signal which, together with noisy output measurements are employed for bounding the parameters of the linear dynamic system
A power manager with balanced quality of service for energy-harvesting wireless sensor nodes

Future Internet of Things is paving the way for the proliferation of Wireless Sensor Networks (WSNs). To overcome the limited energy in batteries, WSN nodes are relying on everlasting environmental energy. Moreover, a Power Manager (PM) is also embedded in each WSN node to guarantees that the total consumed energy is equal to the harvested energy for a long period, leading to Energy Neutral Operation (ENO) with a theoretically infinite lifetime. In this paper, a new PM for WSN nodes powered by periodic sources (e.g. ambient energy is not available during the full harvesting cycle) is proposed. Not only respecting the ENO condition, our PM is able to balance the Quality of Service (QoS) during the whole cycle to provide regular data tracking, which is essential for WSN applications like monitoring. Simulations on OMNET++ show that our PM can improve the QoS during the absence of energy by a factor up to 84% compared to state-of-the-art PMs, while guaranteeing the same global QoS.
Locally Weighted Projection Regression : An O(n) Algorithm for Incremental Real Time Learning in High Dimensional Space

Locally weighted projection regression is a new algorithm that achieves nonlinear function approximation in high dimensional spaces with redundant and irrelevant input dimensions. At its core, it uses locally linear models, spanned by a small number of univariate regressions in selected directions in input space. This paper evaluates different methods of projection regression and derives a nonlinear function approximator based on them. This nonparametric local learning system i) learns rapidly with second order learning methods based on incremental training, ii) uses statistically sound stochastic cross validation to learn iii) adjusts its weighting kernels based on local information only, iv) has a computational complexity that is linear in the number of inputs, and v) can deal with a large number of - possibly redundant - inputs, as shown in evaluations with up to 50 dimensional data sets. To our knowledge, this is the first truly incremental spatially localized learning method to combine all these properties.
A three-phase power-factor correction scheme using an autotransformer and two single-phase Buck rectifiers

This paper presents a three-phase unidirectional rectifier power-factor correction (PFC) using two modified single-phase Buck rectifiers in continuous conduction mode (CCM). The phase reduction technique using an autotransformer based on Scott Connection renders a non-isolated rectifier to operate with unity power factor. The power autotransformer is only 14% of the total output power. Two single-phase buck rectifier interleaved is able to regulate low voltage output. The control system is simple and it has only one voltage control loop. Theoretical analysis, design procedure, complete simulation results with closed loop operation are given and a 4-kW prototype has been implemented in the laboratory which demonstrated to operate successfully with excellent performance.
Automated and Manual Methods of DNA Extraction for Aspergillus fumigatus and Rhizopus oryzae Analyzed by Quantitative Real-Time PCR

ABSTRACT Quantitative real-time PCR (qPCR) may improve the detection of fungal pathogens. Extraction of DNA from fungal pathogens is fundamental to optimization of qPCR; however, the loss of fungal DNA during the extraction process is a major limitation to molecular diagnostic tools for pathogenic fungi. We therefore studied representative automated and manual extraction methods for Aspergillus fumigatus and Rhizopus oryzae. Both were analyzed by qPCR for their ability to extract DNA from propagules and germinated hyphal elements (GHE). The limit of detection of A. fumigatus and R. oryzae GHE in bronchoalveolar lavage (BAL) fluid with either extraction method was 1 GHE/ml. Both methods efficiently extracted DNA from A. fumigatus, with a limit of detection of 1 × 102 conidia. Extraction of R. oryzae by the manual method resulted in a limit of detection of 1 × 103 sporangiospores. However, extraction with the automated method resulted in a limit of detection of 1 × 101 sporangiospores. The amount of time to process 24 samples by the automated method was 2.5 h prior to transferring for automation, 1.3 h of automation, and 10 min postautomation, resulting in a total time of 4 h. The total time required for the manual method was 5.25 h. The automated and manual methods were similar in sensitivity for DNA extraction from A. fumigatus conidia and GHE. For R. oryzae, the automated method was more sensitive for DNA extraction of sporangiospores, while the manual method was more sensitive for GHE in BAL fluid.
Disclosure of Transgender Identity and Status in the Context of Friendship

This study focuses on understanding disclosure of transgender identity within the context of friendship. Participants were 536 individuals who self-identified as transgender or gender variant. Participants completed an online questionnaire regarding friendship experiences. Thematic analysis focused on understanding experiences of identity disclosure to friends. Participants reported positive and negative experiences associated with the identity disclosure process, with responses falling into five distinct categories: positive or affirming responses, negative responses, a variation of responses, an impact on the friendship status, and emotional responses from friends. Within these five theme categories, distinct subcategories were apparent including responses that reflected support, physical violence, gaining or losing friends, and friends being unsurprised or not caring about the disclosure. These findings point to the ways in which the friendship experiences for transgender individuals are complex and unique. Clinical implications for understanding the needs of clients regarding disclosure of transgender identity and status to friends are discussed.
Palaeobiology of Hyaenodon exiguus (Hyaenodonta, Mammalia) based on morphometric analysis of the bony labyrinth

Species of the extinct genus Hyaenodon were among the largest carnivorous mammals from the Late Eocene through Early Miocene in North America, Europe and Asia. The origin, phylogeny and palaeobiology of Hyaenodonta are still ambiguous. Most previous studies focused on teeth and dental function in these highly adapted species, which might be influenced by convergent morphologies. The anatomy of the bony labyrinth in vertebrates is generally quite conservative and, additionally, was used in functional–morphological studies. This study provides the first anatomical description of the bony labyrinth of the extinct European species Hyaenodon exiguus in comparison to selected extant carnivoran taxa discussed from a functional–morphological perspective. Hyaenodon exiguus may have occupied a hyaena‐like dietary niche with a semi‐arboreal lifestyle, based on the relative height, width and length of the semicircular canals of the inner ear. However, this contradicts previous functional–morphological studies focusing on the diameter of the canals, which presumably represent the signal of locomotion mode.
Economic Impacts of AAG Conferences

This paper estimates various economic impacts of the annual conferences of the Association of American Geographers (AAG) on the states in which they have been held, from 1983 to 1994. It uses data on the number of registrants at these conferences, the average expenditures and durations of stay of these individuals, and the sectoral distribution of these expenditures. Input-output analysis was employed to estimate the indirect and induced impacts on each state or province. Aggregate expenditures ranged from $890,000 (Denver in 1983) to $2.5 million (Toronto in 1990), while the effect on statewide output ranged from $1.64 million to $4.67 million (same cities). On average, state or provincial output increased by $2.86 million, 90.9 jobs were created, and $717,000 in personal income was generated. These impacts have gradually increased over the time period in question.
Improved Method for Ex Ovo-Cultivation of Developing Chicken Embryos for Human Stem Cell Xenografts

The characterization of human stem cells for the usability in regenerative medicine is particularly based on investigations regarding their differentiation potential in vivo. In this regard, the chicken embryo model represents an ideal model organism. However, the access to the chicken embryo is only achievable by windowing the eggshell resulting in limited visibility and accessibility in subsequent experiments. On the contrary, ex ovo-culture systems avoid such negative side effects. Here, we present an improved ex ovo-cultivation method enabling the embryos to survive 13 days in vitro. Optimized cultivation of chicken embryos resulted in a normal development regarding their size and weight. Our ex ovo-approach closely resembles the development of chicken embryos in ovo, as demonstrated by properly developed nervous system, bones, and cartilage at expected time points. Finally, we investigated the usability of our method for trans-species transplantation of adult stem cells by injecting human neural crest-derived stem cells into late Hamburger and Hamilton stages (HH26–HH28/E5—E6) of ex ovo-incubated embryos. We demonstrated the integration of human cells allowing experimentally easy investigation of the differentiation potential in the proper developmental context. Taken together, this ex ovo-method supports the prolonged cultivation of properly developing chicken embryos enabling integration studies of xenografted mammalian stem cells at late developmental stages.
Graphic Realizations of Joint-Degree Matrices

In this paper we introduce extensions and modifications of the classical degree sequence graphic realization problem studied by Erd\H{o}s-Gallai and Havel-Hakimi, as well as of the corresponding connected graphic realization version. We define the joint-degree matrix graphic (resp. connected graphic) realization problem, where in addition to the degree sequence, the exact number of desired edges between vertices of different degree classes is also specified. We give necessary and sufficient conditions, and polynomial time decision and construction algorithms for the graphic and connected graphic realization problems. These problems arise naturally in the current topic of graph modeling for complex networks. From the technical point of view, the joint-degree matrix realization algorithm is straightforward. However, the connected joint-degree matrix realization algorithm involves a novel recursive search of suitable local graph modifications. Also, we outline directions for further work of both theoretical and practical interest. In particular, we give a Markov chain which converges to the uniform distribution over all realizations. We show that the underline state space is connected, and we leave the question of the mixing rate open.
Treatment of psoriatic nails with tazarotene cream 0.1% vs. clobetasol propionate 0.05% cream: a double-blind study.

t azarotene 1.13 (0.88) 0.28 (0.45) 0.97 (0.71) Clobetasol 1.09 (0.99) 0.36 (0.48) 0.97 (0.85) Onycholysis t azarotene 1.97 (1.27) 0.82 (0.73) 1.54 (1.00) Clobetasol 1.90 (1.28) 0.82 (0.62) 1.73 (1.09) Hyperkeratosis t azarotene 1.80 (1.04) 0.36 (0.48) 0.97 (0.80) Clobetasol 1.70 (0.95) 0.58 (0.66) 1.56 (0.83) Salmon patches t azarotene 1.15 (0.89) 0.17 (0.38) 0.69 (0.72) Clobetasol 1.07 (0.78) 0.19 (0.45) 0.85 (0.61)
Accent imitation positively affects language attitudes

People in conversation tend to accommodate the way they speak. It has been assumed that this tendency to imitate each other's speech patterns serves to increase liking between partners in a conversation. Previous experiments examined the effect of perceived social attractiveness on the tendency to imitate someone else's speech and found that vocal imitation increased when perceived attractiveness was higher. The present experiment extends this research by examining the inverse relationship and examines how overt vocal imitation affects attitudes. Participants listened to sentences spoken by two speakers of a regional accent (Glaswegian) of English. They vocally repeated (speaking in their own accent without imitating) the sentences spoken by a Glaswegian speaker, and subsequently imitated sentences spoken by a second Glaswegian speaker (order counterbalanced across participants). After each repeating or imitation session, participants completed a questionnaire probing the speakers' perceived power, competence, and social attractiveness. Imitating had a positive effect on the perceived social attractiveness of the speaker compared to repeating. These results are interpreted in light of Communication Accommodation Theory.
The impact of liquid cooling on 3D multi-core processors

Recently, 3D integration has been regarded as one of the most promising techniques due to its abilities of reducing global wire lengths and lowering power consumption. However, 3D integrated processors inevitably cause higher power density and lower thermal conductivity, since the closer proximity of heat generating dies makes existing thermal hotspots more severe. Without an efficient cooling method inside the package, 3D integrated processors should suffer severe performance degradation by dynamic thermal management as well as reliability problems. In this paper, we analyze the impact of the liquid cooling on a 3D multi-core processor compared to the conventional air cooling. We also evaluate the leakage power consumption and the lifetime reliability depending on the temperature of each functional unit in the 3D multi-core processor. The simulation results show that the liquid cooling reduces the temperature of the L1 instruction cache (the hottest block in this evaluation) by as much as 45 degrees, resulting in 12.8% leakage reduction, on average, compared to the conventional air cooling. Moreover, the reduced temperature of the L1 instruction cache also improves the reliability of electromigration, stress migration, time-dependent dielectric breakdown, thermal cycling, and negative bias temperature instability significantly.
Deletion of the Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Auxiliary Subunit TRIP8b Impairs Hippocampal Ih Localization and Function and Promotes Antidepressant Behavior in Mice

Output properties of neurons are greatly shaped by voltage-gated ion channels, whose biophysical properties and localization within axodendritic compartments serve to significantly transform the original input. The hyperpolarization-activated current, Ih, is mediated by hyperpolarization-activated cyclic nucleotide-gated (HCN) channels and plays a fundamental role in influencing neuronal excitability by regulating both membrane potential and input resistance. In neurons such as cortical and hippocampal pyramidal neurons, the subcellular localization of HCN channels plays a critical functional role, yet mechanisms controlling HCN channel trafficking are not fully understood. Because ion channel function and localization are often influenced by interacting proteins, we generated a knock-out mouse lacking the HCN channel auxiliary subunit, tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b). Eliminating expression of TRIP8b dramatically reduced Ih expression in hippocampal pyramidal neurons. Loss of Ih-dependent membrane voltage properties was attributable to reduction of HCN channels on the neuronal surface, and there was a striking disruption of the normal expression pattern of HCN channels in pyramidal neuron dendrites. In heterologous cells and neurons, absence of TRIP8b increased HCN subunit targeting to and degradation by lysosomes. Mice lacking TRIP8b demonstrated motor learning deficits and enhanced resistance to multiple tasks of behavioral despair with high predictive validity for antidepressant efficacy. We observed similar resistance to behavioral despair in distinct mutant mice lacking HCN1 or HCN2. These data demonstrate that interaction with the auxiliary subunit TRIP8b is a major mechanism underlying proper expression of HCN channels and Ih in vivo, and suggest that targeting Ih may provide a novel approach to treatment of depression.
Emergent HPWS: why HRM may not be needed to build a high-performance work system

Purpose – The purpose of this study is to explore the antecedents of high-performance work systems (HPWS). HPWS promise workplaces that are both highly productive and offer employees high levels of job satisfaction. The existing literature tends to see HPWS as outcomes of planned change initiated by management as part of an human resource management (HRM) strategy. We question this assumption and show that under favourable conditions, HPWS may emerge from workers’ self-organization. Design/methodology/approach – A qualitative case study of a department producing automotive components was conducted. Empirical material was collected through participant observation. The material was coded for recurring themes and used to construct an explanatory model. Findings – HPWS may emerge in the absence of managerial or HRM interventions. The emergence and reproduction of HPWS can be explained by a shop-floor culture of craftsmanship, worker solidarity and jobs with high levels of task significance and task identity.
Failure Imagery Reduces Self-Reflectivity in Individuals High in Activity Inhibition

The present research tested the effects of failure imagery on the structure of conscious thought. Based on prior research which shows that (a) individuals high in activity inhibition (as measured by the picture-story exercise) tend to suppress negative mood-relevant thought and (b) suppression can be accomplished by shifting to a low level of thinking, it was assumed that failure imagery induces a shift toward low-level thinking in individuals high in activity inhibition. Participants had to imagine either successfully achieving two important goals they were currently pursuing or failing to do so. After the imagination task, they were asked to work on a stream-of-consciousness writing task. Protocols were analyzed for self-reflectivity (operationalized as the frequency of using the pronoun “I”) and awareness of emotions. The lowest level of self-reflectivity was found among individuals high in activity inhibition who imagined a failure of goal pursuit. This result is discussed with respect to the long-term consequences of suppressing negative mood-relevant thought.
High-performance human resource practices moderate flight attendants’ organizational commitment and organizational citizenship behavior

The aim in this study was to examine the direct effect of organizational commitment on the organizational citizenship behavior (OCB) of flight attendants employed by 6 airlines in Taiwan, and to analyze the moderating role of high-performance human resource practices (HRP) at the organizational level. Data were analyzed via a cross-level analysis using hierarchical linear modeling. Results showed that when flight attendants’ affective commitment was stronger, they were more likely to exhibit OCB; when the airlines more actively adopted high-performance HRP, the flight attendants were also more likely to exhibit OCB; and when the airlines valued high-performance HRP, the relationship between the flight attendants’ organizational commitment and their OCB behavior was more significant. Managerial implications are discussed and suggestions are made for future research.