Miracle-dz/UniFAR-FTUs huggingface dataset:
The Open Access Israeli Journal of Aquaculture – Bamidgeh

This study was conducted to investigate effect of dietary supplementation of three Bacillus spp. on disease resistance of L. vannamei against Vibrio parahaemolyticus, a main causative pathogen for acute hepatopancreatic necrosis disease (AHPND), and growth performance and feed efficiency. Four diets were prepared by supplementing powder forms of Bacillus spp. (1 × 10 CFU/g) with a combination at 0.2% (BS, B. subtilis only), 0.4% (BS/BP, a mixture of B. subtilis and B. pumilus), and 0.6% (BS/BP/BL, a mixture of B. subtilis, B. pumilus and B. licheniformis) into a control diet (no supplement). Quadruplicate groups of shrimp (average body weight, 0.51 g) per each diet were hand-fed the diets for 33 days. Shrimp fed the BS diet had significantly higher growth performance than those fed the control diet or other diets (BS/BP and BS/BP/BL) (P<0.05). After the feeding trial, the shrimp were challenged with V. parahaemolyticus through an immersion method at a concentration of 2 × 10 CFU/ml water for 193 h. The shrimp groups fed the Bacillus supplemented diets showed significantly increased (P<0.05) cumulative survival rates compared to the control diet group. At the last sampling (193h), AHPND toxin was not detected in shrimp fed BS diet while no hepatopancreas was sampled due to 100% mortality in the control group. The findings indicate that growth performance and disease resistance of L. vannamei against AHPND could be improved when shrimp are fed the tested Bacillus spp. Published as an open-access journal by the Society of Israeli Aquaculture & Marine Biotechnology (SIAMB). To read papers free of charge, please register online at http://www.aquaculturehub. org/group/israelijournalofaquaculturebamidgehija The sale of IJA papers is strictly forbidden
Revisitation of the Family Tie between Münsterberg and Taylor-Woodhouse Illusions

Some observations suggest that, contrary to Taylor and Woodhouse's assumption, a strong relationship exists between the Taylor–Woodhouse and Münsterberg distortion illusions. An attempt is made to show that each of the major explanations put forward to account for the occurrence of the Münsterberg effect suits the Taylor–Woodhouse one as well.
Salirhabdus salicampi sp. nov., a halotolerant bacterium isolated from a saltern.

A Gram-stain-positive, halotolerant bacterium, designated strain BH128T, was isolated from soil of a saltern located at Bigeum Island in south-west Korea. Cells were aerobic, motile, spore-forming rods and grew at 15-53 °C (optimum, 35 °C), at pH 5.5-9.0 (optimum, pH 7.0) and at salinities of 0-16 % (w/v) NaCl (optimum, 8 % NaCl). The predominant isoprenoid quinone was menaquinone-7 (MK-7), and the cell-wall peptidoglycan type was A1γ, with meso-diaminopimelic acid as the diagnostic diamino acid. The major fatty acids were iso-C15 : 0, anteiso-C15 : 0, iso-C17 : 0 and anteiso-C17 : 0. The polar lipid pattern consisted of diphosphatidylglycerol, phosphatidylglycerol, phosphatidylethanolamine and four unknown phospholipids. The DNA G+C content was 36.5 mol%. Phylogenetic analyses based on 16S rRNA gene sequences indicated that strain BH128T belonged to the genus Salirhabdus and showed highest similarity to Salirhabduseuzebyi CVS-14T (95.8 %). On the basis of the phylogenetic, phenotypic and chemotaxonomic analyses in this study, strain BH128T is considered to represent a novel species of the genus Salirhabdus, for which the name Salirhabdussalicampi sp. nov. is proposed. The type strain is BH128T (=KACC 18690T=NBRC 111874T).
Time use on an average work day for employed persons ages 25 to 54 with children

A growing number of personal informatics (PI) systems have been designed to break the habit of prolonged sitting and to encourage physical activity during workdays and leisure hours. Few studies, however, have investigated the nature of local movement and mobility in workspaces. Relatively little is known about how such movement patterns are shaped and in what ways micro-mobility in workplaces could be increased. By undertaking a concept-driven design approach, and on the basis of our ethnographic prestudy, we introduce a conceptual framework. In this conceptual framework, we indicate the five main agencies that shape local movement and mobility among office workers. On the basis of this empirical and conceptual work, two prototypes, the non-exercise activity thermogenesis (NEAT)-Lamp and Talking Tree, have been designed, implemented and observed in an office environment. This paper describes this design project and articulates the role of discussions in socially established settings in work environments in order to increase daily movement. The paper concludes by highlighting not only technology, but also collective reflections to spark behavioral change in office environments as social settings.
Analyzing Elements of Letters in a Letter Management System

This paper describes analyzing elements of letters in a letter management system. The primary elements of a letter are a sender, a receiver, and terms which are words and named entities appeared in the letter. A letter management system is developed for letters in the Avery Brundage Collection, named LMBC. By analyzing a collection of such letters, exchanges of letters among persons, and topics and/or contents in the letters are made clear. Then, named entities play important role not only for representing letters, but also for analyzing them. Named entities are extracted from a letter using the definitions of named entities, since some different representations are appeared for one named entity. LMBC provides some useful mechanisms. First, exchanges of letters between their senders and receivers are visualized. Second, words/named entities are counted, after synonym resolution is applied. Moreover, co-occurrence relationships of named entities are examined. Then some of named entities are co-occurred frequently. Such co-occurred named entities are formed into one concept, and this concept is treated as one node when co-occurrence relation is represented in a graph. Furthermore, relationships of two named entities are obtained by traversing connections between them. Using these mechanisms exchanges of letters and co-occurrences of named entities are depicted in suitable graphs. Interrelationships among named entities are made clear.
LL-37-induced host cell cytotoxicity depends on cellular expression of the globular C1q receptor (p33).

The human host-defence peptide (HDP) LL-37 not only displays anti-microbial activity but also immune-modulating properties that trigger intracellular signalling events in host cells. Since the cytolytic activity of high LL-37 concentrations affects cell viability, the function of LL-37 requires tight regulation. Eukaryotic cells therefore benefit from protective measures to prevent harmful effects of LL-37. p33, also known as globular C1q receptor (gC1qR), is reported to act as an LL-37 antagonist by binding the peptide, thereby reducing its cytotoxic activity. In the present report, we show that high levels of endogenous p33 correlate with an increased viability in human cells treated with LL-37. Sub-cellular localization analysis showed p33 distribution at the mitochondria, the plasma membrane and in the cytosol. Strikingly, cytosolic overexpression of p33 significantly antagonized detrimental effects of LL-37 on cell fitness, whereas the reverse effect was observed by siRNA-induced down-regulation of p33. However, modulation of p33 expression had no effect on LL-37-induced plasma membrane pore forming capacity pointing to an intracellular mechanism. A scavenging function of intracellular p33 is further supported by co-immunoprecipitation experiments, showing a direct interaction between intracellular p33 and LL-37. Thus, our findings support an important role of intracellular p33 in maintaining cell viability by counteracting LL-37-induced cytotoxicity.
Photonic High-Power 160-GHz Signal Generation by Using Ultrafast Photodiode and a High-Repetition-Rate Femtosecond Optical Pulse Train Generator

We demonstrate photonic high-power MMW generation at subTHz (160 GHz) frequencies by using ultrafast near-ballistic unitraveling carrier photodiodes (NBUTC-PD), which have a miniaturized active area (24 μm2 ) and flip-chip bonding package for good heat-sinking. Under optical sinusoidal signal excitation with a ~85% modulation depth, 165-GHz optical-to-electrical 3-dB bandwidth, 18-mA saturation current, +5.11-dBm maximum output power at 160-GHz operating frequency has been demonstrated. In order to further mitigate device-heating, we developed a high-power pulsed optical signal source with increased optical modulation depth: a femtosecond optical short-pulse generator with extremely high repetition rate (160 GHz) and pulsewidth as short as 285 fs. With this novel source, we generated high MMW power (+7.8 dBm) with an effective 120% optical modulation depth at 160 GHz directly from the NBUTC-PD.
Nanoindentation of Au and Pt/Cu thin films at elevated temperatures

This paper describes the nanoindentation technique for measuring sputter-deposited Au and Cu thin films’ mechanical properties at elevated temperatures up to 130 °C. A thin, 5-nm Pt layer was deposited onto the Cu film to prevent its oxidation during testing. Nanoindentation was then used to measure elastic modulus and hardness as a function of temperature. These tests showed that elastic modulus and hardness decreased as the test temperature increased from 20 to 130 °C. Cu films exhibited higher hardness values compared to Au, a finding that is explauned by the nanocrystalline structure of the film. Hardness was converted to the yield stress using both the Tabor relationship and the inverse method (based on the Johnson cavity model). The thermal component of the yield-stress dependence followed a second-order polynomial in the temperature range tested for Au and Pt/Cu films. The decrease in yield stress at elevated temperatures accounts for the increased interfacial toughness of Cu thin films.
VERILOG based simulation of ASK, FSK, PSK, QPSK digital modulation techniques

This paper presents a general architectural overview regarding elementary method of VERILOG HDL based code simulation for fundamental and widely used digital modulation techniques such as Binary Amplitude-shift keying (BASK), Binary Frequency-shift keying (BFSK), Binary Phase-shift keying (BPSK) and Quadrature Phase Shift Keying(QPSK). In this work the idea of sinusoidal signals that have been generated is plain sailing in nature and based on fundamentals of signal sampling and quantization. Such concept of sinusoidal signals generation is not unfamiliar but somehow simplified using sampling and quantization in time and amplitude domain, respectively. The whole simulation is done on Model Sim and Xilinx-ISE using VERILOG Hardware descriptive language. The work has been accomplished on Thirty two bit serial data transmission with self-adjustable carrier frequency and bit duration length.
QSDN-WISE: A New QoS-Based Routing Protocol for Software-Defined Wireless Sensor Networks

Today, a wide variety of applications with different requirements are rapidly developed in industrial wireless sensor networks, and providing the Quality of Service (QoS) for this kind of communication network is inevitable. It is difficult to solve the problems of poor adaptability and difficulty in the implementation of the QoS-based network configuration and management in traditional network architecture. We present a hierarchical software-defined network architecture for wireless sensor networks, which makes the complex network management possible and the system more adaptable. Furthermore, we propose a QoS-based routing protocol, called QSDN-WISE, which consists of a clustering algorithm, a routing algorithm, and local network maintenance. A double-cluster head-based uneven clustering algorithm, called DCHUC, avoids the energy hole phenomenon and reduces the workload of a single cluster head. The centralized QSDN-WISE routing algorithm constructs two heterogeneous forwarding paths for nodes, which meets the requirements for different data levels. Local network maintenance reduces the number of control messages in the network. The simulation results indicate that the QSDN-WISE can provide the QoS support for data with different requirements, balance the network energy consumption, and prolong the network’s lifetime.
IFN-β Inhibits Dendritic Cell Migration through STAT-1–Mediated Transcriptional Suppression of CCR7 and Matrix Metalloproteinase 9

IFN-β is an approved therapeutic option for the treatment of multiple sclerosis. The molecular mechanisms underlying the effects of IFN-β in multiple sclerosis are not fully understood. Migration of dendritic cells (DCs) from the inflammatory site to draining lymph nodes for Ag presentation and activation of naive T cells and to the CNS for reactivation of encephalitogenic T cells requires CCR7 and matrix metalloproteinase (MMP)-9 expression. This article reports for the first time that IFN-β inhibits CCR7 expression and MMP-9 production in mature DCs and reduces their migratory capacity. The effect of IFN-β is mediated through STAT-1. In vivo treatment with IFN-β results in lower numbers of DCs migrating to the draining lymph node following exposure to FITC and in reduced expression of CCR7 and MMP-9 in splenic CD11c+ DCs following LPS administration. IFN-β and IFN-γ share the same properties in terms of their effects on CCR7, MMP-9, and DC migration, but they have opposite effects on IL-12 production. In addition, IFN-β–treated DCs have a significantly reduced capacity for activating CD4+ T cells and generating IFN-γ–producing Th1 cells. The suppression of mature DC migration through negative regulation of CCR7 and MMP-9 expression represents a novel mechanism for the therapeutic effect of IFN-β.
Investigation on nondestructive evaluation of pipelines using infrared thermography

Different kinds of defects in the pipeline heat insulation layer (PHIL), both in the inner and outer sides, and leakage holes of the pipeline, with or without PHIL, are made artificially and studied using infrared thermography. The detectability of the defect in the PHIL and the leakage of the pipeline are investigated and the relationships between the maximum temperature of the defects in the thermal images and the depth and size of the defects in the PHIL are also studied. In addition, the practical inspection work is done to a boiler system of a warship. Both the simulated study in the lab and the practical applications have certified the effectiveness of thermography.
Efficacy of Some Rhizosphere Microorganisms in Controlling Fusarium Wilt of Tomato (Lycopersicon esculentum)

An experiment was conducted at the Disease Diagnostic Laboratory and Net House of Plant Pathology Department, Sher-e-Bangla Agricultural University, Dhaka during July 2011 to June 2012 to investigate the efficacy of some antagonistic rhizosphere microorganisms against Fusarium oxysporum f. sp. lycopersici causing Fusarium wilt of tomato. Probable 20 antagonistic bacterial isolates and one antagonistic fungal isolate ( Trichoderma harzianum ) from rhizosphere soil were screened out against F. oxysporum f. sp. lycopersici . Out of 20 bacterial isolates, only four (Iso-1, Iso-2, Iso-3 and Iso-4) were found effective in dual culture method. Out of all antagonists, Trichoderma harzianum produced the highest inhibition zone (75.75 %), while the lowest inhibition zone (28.39 %) was produced by Iso- 2. In blotter method, the highest prevalence of Fusarium oxysporum was observed in control (11.25%), while the lowest was in Iso-1 (0.58%) treated seeds. DOI: http://dx.doi. org/10.3329/agric.v11i2. 17494 The Agriculturists 2013; 11(2) 96-103
Mucosal Vaccine Targeting Improves Onset of Mucosal and Systemic Immunity to Botulinum Neurotoxin A1

Absence of suitable mucosal adjuvants for humans prompted us to consider alternative vaccine designs for mucosal immunization. Because adenovirus is adept in binding to the respiratory epithelium, we tested the adenovirus 2 fiber protein (Ad2F) as a potential vaccine-targeting molecule to mediate vaccine uptake. The vaccine component (the host cell-binding domain to botulinum toxin (BoNT) serotype A) was genetically fused to Ad2F to enable epithelial binding. The binding domain for BoNT was selected because it lies within the immunodominant H chain as a β-trefoil (Hcβtre) structure; we hypothesize that induced neutralizing Abs should be protective. Mice were nasally immunized with the Hcβtre or Hcβtre-Ad2F, with or without cholera toxin (CT). Without CT, mice immunized with Hcβtre produced weak secretory IgA (sIgA) and plasma IgG Ab response. Hcβtre-Ad2F-immunized mice produced a sIgA response equivalent to mice coimmunized with CT. With CT, Hcβtre-Ad2F-immunized mice showed a more rapid onset of sIgA and plasma IgG Ab responses that were supported by a mixed Th1/Th2 cells, as opposed to mostly Th2 cells by Hcβtre-dosed mice. Mice immunized with adjuvanted Hcβtre-Ad2F or Hcβtre were protected against lethal BoNT serotype A challenge. Using a mouse neutralization assay, fecal Abs from Hcβtre-Ad2F or Hcβtre plus CT-dosed mice could confer protection. Parenteral immunization showed that the inclusion of Ad2F enhances anti-Hcβtre Ab titers even in the absence of adjuvant. This study shows that the Hcβtre structure can confer protective immunity and that use of Hcβtre-Ad2F gives more rapid and sustained mucosal and plasma Ab responses.
Masculinity, femininity, & androgyny : the interaction of college students with preschoolers

The relationship between sex-typing and the interaction of college students with 2to 4-year-old male and female children was examined. Seventy-one Introductory Psychology students were administered the Bern Sex-Role Inventory (BSRI), which was scored in terms of the 7 factors introduced by Walker & Preston (1979). Small groups of 3 and 4 individuals were randomly selected to spend 20 minutes in the Child Development Lab, where they had the opportunity to interact with the children, to play with the toys, to observe, and to interact with each other. The behavior of each individual within the groups of students was recorded by trained raters observing through a 1-way mirror. Although it was predicted that the factors of Nurturance and Autonomy would account for the majority of the variance, a cannonical correlation failed to indicate significant results. Results are discussed in terms of the behavioral observation technique employed, the predicting value of the BSRI, and implications for future research. Masculinity, Femininity, & Androgyny: The Interaction of College Students with Preschoolers A new wave of research on role behaviors stereotypically associated with males and females was introduced in 1974 when . Bern developed a measure of sex-typing based on the assumption that masculinity and femininity are two independent dimensions rather than opposite ends of a bipolar continuum. Bern's research was strongly influenced by the :theoretical· work of Bakan (1966), describing his bipolar constructs of agency and communion. For Bakan, agency and communion encompass much of the masculine-feminine stereotype respectively (Brown & Marks, 1969). Bern, however, points out a major limitation of a sexrole dichotomy in that it obscures the possibility that many individuals are both masculine and feminine, -or ''androgynous" (Bern, :J 974) . Walker & Pres ton ( 1979) go beyond the two i ndependent dimensions of ma·scul inity -and femfni rii ty originally measured by Bern's scale. Their factor analysis of the Bern Sex-Role Inventory (BSRI) yields 8 independent components involved in sextyping. Rather than assigning a sex-type as proposed by Bern (1974), the multiple dimension profile would enable both males and females to demonstrate groups of masculine and feminine characteristics (Walker & Preston, 1979). It is this progression in the research on sex-roles, with an emphasis on the situational influence on sex-typed behavior, which lays the groundwork for
The role of caldesmon in the regulation of endothelial cytoskeleton and migration

The actin‐ and myosin‐binding protein, caldesmon (CaD) is an essential component of the cytoskeleton in smooth muscle and non‐muscle cells and is involved in the regulation of cell contractility, division, and assembly of actin filaments. CaD is abundantly present in endothelial cells (EC); however, the contribution of CaD in endothelial cytoskeletal arrangement is unclear. To examine this contribution, we generated expression constructs of l‐CaD cloned from bovine endothelium. Wild‐type CaD (WT‐CaD) and truncated mutants lacking either the N‐terminal myosin‐binding site or the C‐terminal domain 4b (containing actin‐ and calmodulin‐binding sites) were transfected into human pulmonary artery EC. Cell fractionation experiments and an actin overlay assay demonstrated that deleting domain 4b, but not the N‐terminal myosin‐binding site, resulted in decreased affinity to both the detergent‐insoluble cytoskeleton and soluble actin. Recombinant WT‐CaD co‐localized with acto‐myosin filaments in vivo, but neither of CaD mutants did. Thus both domain 4b and the myosin‐binding site are essential for proper localization of CaD in EC. Overexpression of WT‐CaD led to cell rounding and formation of a thick peripheral subcortical actin rim in quiescent EC, which correlated with decreased cellular migration. Pharmacological inhibition of p38 MAPK, but not ERK MAPK, caused disassembly of this peripheral actin rim in CaD‐transfected cells and decreased CaD phosphorylation at Ser531 (Ser789 in human h‐CaD). These results suggest that CaD is critically involved in the regulation of the actin cytoskeleton and migration in EC, and that p38 MAPK‐mediated CaD phosphorylation may be involved in endothelial cytoskeletal remodeling. © 2004 Wiley‐Liss, Inc.
New Mitochondrial DNA Homoplasmic Mutations Associated With Japanese Patients With Type 2 Diabetes

Epidemiological studies have shown that patients with type 2 diabetes are more likely to have affected mothers than fathers and that the disease is often transmitted in a mode of maternal inheritance (1,2). Because transmission of mitochondria is exclusively maternal (3), mitochondrial DNA (mtDNA) mutations have been implicated in the maternal inheritance of diabetes (4). However, mtDNA mutation at 3243 has been reported in only 1-1.5% of patients with type 2 diabetes (5,6). Therefore we postulated that other mtDNA mutations may be associated with type 2 diabetes. Recently, using polymerase chain reaction (PCR)-restriction fragment (RF)-single-strand conformation polymorphism (SSCP) analysis (7), we confirmed 56 mtDNA mutations in Japanese subjects (8). In this study, we investigated the prevalence of 5 mtDNA mutations, including 3 mutations that we reported (8) in Japanese subjects. The study was performed in accordance with the principles of the Declaration of Helsinki. Informed consent was obtained from all subjects, and the study design was approved by the Ethical Committee of Yamanashi Medical University. Peripheral blood was obtained from 253 unrelated patients (mean age: 55.7 ± 1.8 years) with type 2 diabetes in the order of their visits to outpatient Clinic of Yamanashi Medical University Hospital. We also recruited 345 healthy control subjects (mean age: 43.6 ± 1.6 years) with no family history of diabetes and normal oral glucose tolerance or HbAlc, who visited the Isawa Curehouse or Koseiren Health Center for medical checkups. Genomic DNA was obtained from peripheral leukocytes using a DNAQuick kit (Dainippon Pharmaceutical, Osaka, Japan). mtDNA mutations were detected either by PCR-SSCP or PCR-restriction fragment length polymorphism (RFLP) analyses. Two primer pairs were used: primer pair A, for-