Miracle-dz/UniFAR-FTUs huggingface dataset:
College Student Mental Health: The Relationship Between Depression and Emotional Intelligence Using the Student Relationships Assessment

The purpose for conducting this study was to investigate the relationship between emotional relational intelligence (ERQ) and depression in college students. The significance of this study is based on the additional support that can be provided to students with increased information and understanding of emotional relational intelligence and depression. In an effort to help college students achieve their educational goals and aspirations, the researcher suggests that emotional relational intelligence can be beneficial. The relationship between depression and emotional relational intelligence may provide insight on how to support and care for college students who are struggling with depressive symptomology. The results of the study indicate a statistically significant negative moderate correlation between emotional relational intelligence and depression in the population of students who completed the Student Relationships Assessment in fall 2009 and fall 2010; a statistically significant negative moderate correlation between emotional management and depression in the population of students who completed the Student Relationships Assessment in fall 2009 and fall 2010; and statistically significant negative, yet weak, correlation between emotion perception and depression in the population of students who completed the Student Relationships Assessment in fall 2009 and fall 2010. Furthermore, the study indicated that there was a significant statistical difference between the depression scores of males and females in the population of students who completed the Student Relationships Assessment in fall 2009 and fall 2010. There was no statistical difference between the emotional relational intelligence scores of males and females in the population of students who completed the Student Relationships Assessment in fall
Seismology of triple-mode classical Cepheids of the Large Magellanic Cloud

We interpret the three periods detected in OGLE LMC Cepheids SC3-360128 and SC5-338399 as corresponding to the first three overtones of radial pulsations. This interpretation imposes stringent constraints on parameters of the stars and on their evolutionary status, which could only be the first crossing of the instability strip. Evolutionary models reproducing measured periods exist only in a restricted range of metallicities (Z = 0.004-0.007). The models impose an upper limit to the extent of overshooting from the convective core. Absolute magnitude of each star is confined to a narrow interval, which allows us to derive a new estimate of the distance to the LMC. We obtain the value of m - M ranging from 18 m . 34 to 18 m . 53 with a systematic difference between the two stars of about 0 m . 13, The rates of period change predicted by the models are formally in conflict with the derived observational limits, though the uncertainties of measured P may have been underestimated. If this discrepancy is confirmed, it would constitute a significant challenge to the stellar evolution theory.
An anatomy of normal and malignant gene expression

A gene's expression pattern provides clues to its role in normal physiology and disease. To provide quantitative expression levels on a genome-wide scale, the Cancer Genome Anatomy Project (CGAP) uses serial analysis of gene expression (SAGE). Over 5 million transcript tags from more than 100 human cell types have been assembled. To enhance the utility of this data, the CGAP SAGE project created SAGE Genie, a web site for the analysis and presentation of SAGE data (http://cgap.nci.nih.gov/SAGE). SAGE Genie provides an automatic link between gene names and SAGE transcript levels, accounting for alternative transcription and many potential errors. These informatics advances provide a rapid and intuitive view of transcript expression in the human body or brain, displayed on the SAGE Anatomic Viewer. We report here an easily accessible view of nearly any gene's expression in a wide variety of malignant and normal tissues.
Ion diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum.

1. The validity of the macroscopic laws of ion diffusion was critically examined within the microenvironment of the extracellular space in the rat cerebellum using ion‐selective micropipettes and ionophoretic point sources. 2. The concepts of volume averaging, volume fraction (alpha) and tortuosity (lambda) were defined and shown to be theoretically appropriate for quantifying diffusion in a complex medium such as the brain. 3. Diffusion studies were made with the cations tetramethylammonium and tetraethylammonium and the anions alpha‐naphthalene sulphonate and hexafluoro‐arsenate, all of which remained essentially extracellular during the measurements. Diffusion parameters were measured for a period of 50s and over distances of the order of 0.1 mm. 4. Measurements of the diffusion coefficients of the ions in agar gel gave values that were very close to those derivable from the literature, thus confirming the validity of the method. 5. Measurements in the cerebellum did not reveal any systematic influences of ionophoretic current strength, electrode separation, anisotropy, inhomogeneity, charge discrimination or uptake, within the limits tested. 6. The pooled data from measurements with all the ions gave alpha = 0.21 +/‐ 0.02 (mean +/‐ S.E. of mean) and lambda = 1.55 +/‐ 0.05 (mean +/‐ S.E. of mean). 7. These results show that the extracellular space occupies about 20% of the rat cerebellum and that the diffusion coefficient for small monovalent extracellular ions is reduced by a factor of 2.4 (i.e. lambda 2) without regard to charge sign. The over‐all effect of this is to increase the apparent strength of any ionic source in the cerebellum by a factor of lambda 2/alpha, about 12‐fold in the present case, and to modify the time course of diffusion. 8. These conclusions confirm that the laws of macroscopic diffusion are closely obeyed in the cerebellum for small ions in the extracellular space, provided that volume fraction and tortuosity are explicitly taken into account. It is likely that these conclusions are generally applicable to other brain regions and other diffusing substances.
End-to-end Tracing in HDFS

Debugging performance problems in distributed systems is difficult. Thus many debugging tools are being developed to aid diagnosis. Many of the most interesting new tools require information from end-to-end tracing in order to perform their analysis. This paper describes the development of an end-to-end tracing framework for the Hadoop Distributed File System. The approach to instrumentation in this implementation differs from previous ones as it focuses on detailed low-level instrumentation. Such instrumentation encounters the problems of large request flow graphs and a large number of different kinds of graphs, impeding the effectiveness of the diagnosis tools that use them. This report describes how to instrument at a fine granularity and explain techniques to handle the resulting challenges. The current implementation is evaluated in terms of performance, scalability, the data the instrumentation generates, and its ability to be used to solve performance problems.
Population Pharmacokinetics of Enoxaparin in Pediatric Patients

Background: There are no studies evaluating the pharmacokinetics of enoxaparin in the hospitalized pediatric patient population. Objective: To characterize the pharmacokinetics of enoxaparin in pediatric patients. Methods: A retrospective review of inpatients 1 to 18 years of age admitted to our institution who received enoxaparin with anti–factor Xa activity level monitoring was performed. Demographic variables, enoxaparin dosing, and anti–factor Xa activity levels were collected. Population pharmacokinetic analysis was performed with bootstrap analysis. Simulation (n = 10 000) was performed to determine the percentage who achieved targeted anti-Xa levels at various doses. Results: A total of 853 patients (male 52.1%, median age = 12.2 years; interquartile range [IQR] = 4.6-15.8 years) received a mean enoxaparin dose of 0.86 ± 0.31 mg/kg/dose. A median of 3 (IQR = 1-5) anti–factor Xa levels were sampled at 4.4 ± 1.3 hours after a dose, with a mean anti–factor Xa level of 0.52 ± 0.23 U/mL. A 1-compartment model best fit the data, and significant covariates included allometrically scaled weight, serum creatinine, and hematocrit on clearance, and platelets on volume of distribution. Simulations were run for patients both without and with reduced kidney function (creatinine clearance of ≤30 mL/min/1.73 m2). A dose of 1 mg/kg/dose every 12 hours had the highest probability (72.3%) of achieving an anti-Xa level within the target range (0.5-1 U/mL), whereas a dose reduction of ~30% achieved the same result in patients with reduced kidney function. Conclusions: Pediatric patients should initially be dosed at 1-mg/kg/dose subcutaneously every 12 hours for treatment of thromboembolism followed by anti-Xa activity monitoring. Dose reductions of ~30% for creatinine clearance ≤30 mL/min/1.73 m2 are required.
Psychometric Evaluation of Utrecht Work Engagement Scale in an Indian Sample

The objective of this study was to examine the psychometric properties of the Utrecht Work Engagement Scale (UWES) in an Indian sample. The UWES was administered to a total of 450 employees from both public and private sector manufacturing and service organisations in India. Confirmatory factor analyses revealed that the three-factor model demonstrated a better fit when compared to one-factor model for both, the original 17-item and 9-item shortened versions of UWES. However, due to very high inter-correlation between the three dimensions, exploratory factor analyses resulted in two- and one-factor solutions for the 17-item and 9-item versions, respectively. Though the internal consistencies for sub-scales were acceptable, internal consistencies of the complete scales were found to be higher than that for the three sub-scales. The shortened UWES was found to display better psychometric properties than the original 17-item UWES.
Assessment of TP53 Mutations in Benign and Malignant Salivary Gland Neoplasms

Despite advances in the understanding of the pathogenesis of salivary gland neoplasms (SGN), the molecular pathways associated with enhanced tumor growth and cell survival remain to be established. The aim of the present study was to investigate whether TP53 mutations are relevant to SGN pathogenesis and if they impact on p53 protein expression. The study included 18 benign and 18 malignant SGN samples. Two polymorphic microsatellite markers at the TP53 genetic locus were chosen to assess loss of heterozygosity (LOH) in the samples that had matched normal DNA. The TP53 exons 2–11 were amplified by PCR, and all of the products were sequenced. Reverse transcription-PCR of the TP53 open reading frame (ORF) was carried out in the samples that had fresh tissue available, and immunohistochemistry for the p53 protein was performed in all samples. TP53 LOH was only found in two pleomorphic adenomas. We found two missense mutations in exon 7 (one in a pleomorphic adenoma and the other in a polymorphous low grade adenocarcinoma), another in exon 8 (in a carcinoma ex pleomorphic adenoma) and a fourth missense mutation in exon 10 (in a mucoepidermoid carcinoma). In addition, a nonsense mutation was found in exon 8 of an adenoid cystic carcinoma. Several intronic and exonic SNPs were detected. Although almost all of the malignant samples were immunopositive for p53, approximately 37% of the benign samples were positive, including the sample harboring the missense mutation and one of the samples that showed LOH. The complete TP53 ORF could be amplified in all samples analyzed, including the IHC negative samples, the samples showing LOH and one sample displaying a missense mutation. In summary, our results show that TP53 mutations are not a frequent event in SGN and that p53 immunopositivity might not be associated with sequence mutations in SGN.
Heterozygosity and instability of amplified chromosomal insertions in the radioresistant bacterium Deinococcus radiodurans

Natural transformation, duplication insertion, and plasmid transformation in Deinococcus radiodurans, a bacterium that contains 4 to 10 chromosomes per cell, were studied. Duplication insertions were often heterozygous, with some chromosomes containing highly amplified insertions and others containing no insertions. Large amplified regions were apparently deleted by intrachromosomal recombination, generating as by-products extrachromosomal circles consisting of multiple tandem repeats of the amplified sequence. The circles were of heterogenous integer sizes, containing as many as 10 or more amplification units. Two strains that are defective in natural transformation and sensitive to DNA-damaging agents were further characterized. Both strains were defective in duplication insertion. While on strain was normal for plasmid transformation, the other was totally defective in this regard, suggesting that plasmid transfer in D. radiodurans may require recombinational functions.
Learning informally to use the ‘full version’ of teaching games for understanding

This paper examines an experienced teacher’s employment of the teaching games for understanding (TGfU) model in a UK secondary school. The study sought to investigate how the teacher delivered TGfU and those factors that influenced his informal learning of this instructional model. Occupational socialisation was utilised to determine the factors that influenced his use of TGfU. Qualitative data were collected from interviews, lesson observations and documentary evidence. Inductive data analysis indicated the teacher delivered the ‘full version’ of the model largely congruent with the creators’ intentions. The traditional approach to games teaching seen in his childhood and partially learned in higher education were ‘washed out’ by the influence of teaching colleagues and the development of a student-centred approach to teaching games. This study indicates it is possible to overcome traditional approaches to games teaching and informally learn to use TGfU successfully given conducive circumstances and sufficient time.
An embodied semantic processing effect on eye gaze during sentence reading

Abstract The present research examines the effects of body-object interaction (BOI) on eye gaze behaviour in a reading task. BOI measures perceptions of the ease with which a human body can physically interact with a word's referent. A set of high BOI words (e.g. cat) and a set of low BOI words (e.g. sun) were selected, matched on imageability and concreteness (as well as other lexical and semantic variables). Facilitatory BOI effects were observed: gaze durations and total fixation durations were shorter for high BOI words, and participants made fewer regressions to high BOI words. The results provide evidence of a BOI effect on non-manual responses and in a situation that taps normal reading processes. We discuss how the results (a) suggest that stored motor information (as measured by BOI ratings) is relevant to lexical semantics, and (b) are consistent with an embodied view of cognition (Wilson 2002).
Characterization and Modeling of Dynamic Thermal Behavior in CMP

Existing models of chemical mechanical polishing ~CMP! focus on the impact of pressure, velocity, slurry, and pad parameters on material removal rate. To complement these models, we present a model and experimental data for thermal effects in CMP. The energy source and thermal loss mechanisms are calculated and an energy balance formulation is used to predict the energy exchanged between the pad and slurry flowing over it. Experiments are shown to be consistent with this prediction, suggesting that the most significant elements are accounted for. We also describe the dynamic aspect of the process whereby heat is accumulated in the pad during polish and lost to the slurry flowing over the pad while it rotates around before entering under the head again. Our studies indicate that this heating and cooling cycle may be responsible for the transient behavior observed at the beginning of each polish. To analyze the transient thermal behavior observed in the pad, we propose a lumped parameter dynamic model. Simulation results are seen to match well with experimental data for copper polishes. © 2003 The Electrochemical Society. @DOI: 10.1149/1.1560642# All rights reserved. Characterization of chemical mechanical polishing ~CMP! removal rate and rate uniformity have traditionally focused on the use of Preston’s equation to model the mechanics of the polishing process, in which removal rate R is proportional to the product of pressure Pr and relative velocity v with proportionality given by Preston’s coefficient k p ,o rR 5 k pPrv. Depending on the hardness of the polishing film ~e.g., oxide, copper, tungsten! and barrier film ~e.g., nitride, TaN, TiN! , and the chemistry of the slurry, the temperature may vary significantly during polish. A factor not normally considered in Prestonian CMP models is the impact of changes in temperature on material removal. An experiment performed by Chiou et al. examined the chemical removal rates of copper at different temperatures and for different slurries and found that changes of 20°C can result in an order of magnitude increase in removal rates. 1 More recent studies of copper polishes have also observed similarities between the transient increase in temperature due to polish and the increase in removal rate. 2 Other work has observed common patterns between the spatial variation in removal rates for oxide and copper polishes and variation in temperature across the polishing pad. 3 Models for the evolution of topography at the chip and feature scale, including dishing and erosion, all require an equivalent blanket material removal rate parameter. 4,5 Thus an understanding of thermal behavior during polish has become increasingly important for better characterization of CMP at the wafer and chip scale.
Stable Isotope Labeling by Amino Acids in Cell Culture, SILAC, as a Simple and Accurate Approach to Expression Proteomics*

Quantitative proteomics has traditionally been performed by two-dimensional gel electrophoresis, but recently, mass spectrometric methods based on stable isotope quantitation have shown great promise for the simultaneous and automated identification and quantitation of complex protein mixtures. Here we describe a method, termed SILAC, for stable isotope labeling by amino acids in cell culture, for the in vivo incorporation of specific amino acids into all mammalian proteins. Mammalian cell lines are grown in media lacking a standard essential amino acid but supplemented with a non-radioactive, isotopically labeled form of that amino acid, in this case deuterated leucine (Leu-d3). We find that growth of cells maintained in these media is no different from growth in normal media as evidenced by cell morphology, doubling time, and ability to differentiate. Complete incorporation of Leu-d3 occurred after five doublings in the cell lines and proteins studied. Protein populations from experimental and control samples are mixed directly after harvesting, and mass spectrometric identification is straightforward as every leucine-containing peptide incorporates either all normal leucine or all Leu-d3. We have applied this technique to the relative quantitation of changes in protein expression during the process of muscle cell differentiation. Proteins that were found to be up-regulated during this process include glyceraldehyde-3-phosphate dehydrogenase, fibronectin, and pyruvate kinase M2. SILAC is a simple, inexpensive, and accurate procedure that can be used as a quantitative proteomic approach in any cell culture system.
Iconicity in the lab: a review of behavioral, developmental, and neuroimaging research into sound-symbolism

This review covers experimental approaches to sound-symbolism—from infants to adults, and from Sapir’s foundational studies to twenty-first century product naming. It synthesizes recent behavioral, developmental, and neuroimaging work into a systematic overview of the cross-modal correspondences that underpin iconic links between form and meaning. It also identifies open questions and opportunities, showing how the future course of experimental iconicity research can benefit from an integrated interdisciplinary perspective. Combining insights from psychology and neuroscience with evidence from natural languages provides us with opportunities for the experimental investigation of the role of sound-symbolism in language learning, language processing, and communication. The review finishes by describing how hypothesis-testing and model-building will help contribute to a cumulative science of sound-symbolism in human language.
A Different Kind of Blackness: Using Successful Journeys to Examine Students’ Experiences of Secondary Schooling

Black females achieve high standards of success, yet their lived experiences are frequently absent from educational literature in Canada. Using narratives gathered through semistructured interviews and focus group discussions, this thesis documents the navigational strategies adopted by four Black female students to achieve academic success in learning environments that often predicted their failure. The narratives highlight the factors the girls believed contributed to their academic success, how they conceptualized their identity and the role(s) their identity played in their schooling experiences and academic success. Contrary to deficiencies that are often highlighted in studies on the schooling experiences of Black students, using feminist theory, critical race theory and antiracism, coupled with resistance theory shed light on the positive aspects of these Black females’ schooling experiences in Ontario. Such an approach disrupts negative views of Black students as lagging behind in education in Canada. Disseminating the narratives of successful students provides real life examples for other students to imitate in pursuit of academic success amidst educational and societal barriers. On a macro level, these narratives provide education policy makers with different perspectives on how students struggled to achieve academic success within a system that promised to be accessible to
Assessment of the Impacts of Land Use Changes on Nonpoint Source Pollution Inputs Upstream of the Three Gorges Reservoir

In recent years, land use upstream of the Three Gorges Reservoir (TGR) has changed significantly because of the TGR project. In this study, the Soil and Water Assessment Tool (SWAT) model was examined for its ability to assess relationships between land use changes and nonpoint pollutant indexes upstream of the TGR. Results indicated that the SWAT model, calibrated with the adjusted parameters, could successfully reproduce the nonpoint indexes at the water quality monitoring sites in the two rivers. The different land use change types were shown to be sensitive to nonpoint pollutants in the study area. The land use change type from upland to water was the strongest influence on changes in total nitrogen and total phosphorus. An empirical regression equation between nonpoint indexes and different land use change types was developed for the study area by partial least squares regression (PLSR) as follows: Y = b 0 + ∑i=1 m b i X i. This regression equation was useful for evaluating the influence of land use change types on changes in nonpoint pollutants over a long time period. The results from this study may be useful for the TGR management and may help to reduce nonpoint pollutant loads into downstream water bodies.