Miracle-dz/UniFAR-FTUs huggingface dataset:
Optimal MTM spectral estimation based detection for cognitive radio in HDTV

Cognitive radio based systems rely on spectrum sensing techniques to detect whitespaces to exploit. For the sake of ease of implementation, simple schemes such as energy detector have been proposed and studied widely. However, such simple schemes perform far from optimally, thereby affecting the performance of the underlying system. On the other hand sophisticated detectors are difficult to implement, giving rise to a trade-off. This paper explores the idea of using spectral estimates for detection. The case of HDTV based cognitive radio is explored and an optimal detection scheme following multi taper estimation is proposed and studied.
Levels of amputation and limiting factors.

WHATEVER THE INDICATION for amputation, the result is a limb stump. In the case of a hindquarter amputation for chrondrosarcoma of the pelvis the stump as such is non-existent but the level of limb section is mandatory. In other situations and particularly where the pathology is more distal in the limb the precise level of limb section is selected ideally within relatively narrow limits and hopefully after due consideration of all the relevant factors.
CHOROIDAL THICKNESS AFTER INTRAARTERIAL CHEMOTHERAPY FOR RETINOBLASTOMA

Purpose: To measure the choroidal thickness (CT) and analyze the morphologic features of chorioretinal structures using a portable handheld spectral domain-optical coherence tomography in patients with retinoblastoma after intraarterial chemotherapy. Methods: This was a case–control study. Eighteen eyes of 9 patients with unilateral retinoblastoma treated with intraarterial chemotherapy were assessed by spectral-domain optical coherence tomography. Submacular CT was measured at the foveola and at points located 500 &mgr;m and 2 mm from the foveola. The treated eye was compared with the untreated (control) eye. Results: Mean submacular CT was 174 ± 111.1 &mgr;m in the treated eyes and 259 ± 42.2 &mgr;m in the control eyes (P = 0.054). Several point locations showed statistically significant differences comparing CT (treated eye vs. control eye), including subfoveolar (P = 0.030), nasal 0.5 mm (P = 0.037), nasal 2 mm (P = 0.049), and temporal 2 mm (P = 0.031). In 4 patients with ophthalmoscopically visible choroidal atrophy, submacular CT was reduced by 73.3 ± 14.1% compared with the control eye. In 5 patients with no ophthalmoscopically visible choroidal atrophy, submacular CT was reduced by 0.5 ± 11.9% compared with the control eye. Conclusion: Intraarterial chemotherapy for retinoblastoma can cause reduction in subfoveolar CT. Spectral-domain optical coherence tomography confirmed choroid to be thinned in eyes with or without clinical evidence of choroidal atrophy.
Low‐level mosaicism of trisomy 14: Phenotypic and molecular characterization

Trisomy 14 mosaicism is a rare cytogenetic abnormality with a defined and recognizable clinical phenotype. We present a detailed clinical history and physical findings of five patients with low‐level mosaicism of trisomy 14 detected by array‐based comparative genomic hybridization (array‐CGH) analysis or by routine chromosome analysis. These patients exhibited growth and developmental delays with variable severity, congenital anomalies, pigmentary skin lesions, and dysmorphic features. The phenotype of our patients was compared with previously described cases. This report suggests that trisomy 14 mosaicism may be more common than has been previously appreciated and also illustrates the important application of array‐CGH to detect low‐level mosaic chromosome abnormalities. We predict that a wider application of the array‐CGH technology will significantly increase the detection rate of low‐level mosaicism and will subsequently improve our ability to provide a diagnosis for patients with dysmorphic features, congenital anomalies, and developmental delay. © 2008 Wiley‐Liss, Inc.
Frequency distribution of polymorphisms of CYP2C19, CYP2C9, VKORC1 and SLCO1B1 genes in the Yakut population

Allele frequencies of single nucleotide polymorphisms (SNPs) are variable among different populations; therefore the study of SNPs in ethnic groups is important for establishing the clinical significance of the screening of these polymorphisms. The main goal of the research is to study the polymorphisms of CYP2C9, CYP2C19, VKORC1, and SLCO1B1 in Yakuts. Genomic DNA from 229 Yakut subjects were analyzed by real-time polymerase chain reaction (PCR) (SLCO1B1 +521T > C, VKORC1 -1639G>A, CYP2C19 +681G>A, +636G>A, CYP2C9 +430С>T, +1075A>C). Genotype frequencies of polymorphisms in the population of the Yakuts were more characteristic of the Asian population. The results have been included in the software application “Lekgen” that we developed for the interpretation of pharmacogenetic testing. The data of our study obtained on frequency carriers of polymorphisms of genes SLCO1B1, CYP2C19, CYP2C9, VKORC1 among the Yakuts may be useful in developing recommendations for a personalized therapy.
Comparison of Open Circuit Flux Control Capability of a Series Double Excitation Machine and a Parallel Double Excitation Machine

Double excitation synchronous machines combine permanent-magnet (PM) excitation with wound field excitation. The goal behind the principle of double excitation is to combine the advantages of PM-excited machines and wound field synchronous machines. These machines can constitute an energy-efficient solution for vehicle propulsion. This paper presents a comparison of the open circuit flux control capability of two structures of double excitation synchronous machines. First, a review of the state of the art of double excitation machines is presented. Then, the structures of these two machines are presented: one is a series double excitation synchronous machine and the other is a parallel double excitation synchronous machine. Finally, the open circuit flux control capabilities of both structures are compared.
A Protein Kinase Family in Arabidopsis Phosphorylates Chloroplast Precursor Proteins*

A serine/threonine protein kinase that is able to phosphorylate chloroplast-destined precursor proteins was purified from leaf extract of Arabidopsis thaliana and was identified by mass spectrometry. The protein kinase, encoded by AT2G17700, belongs to a small protein family comprising in addition AT4G35780 and AT4G38470. All three proteins were expressed heterologously in Escherichia coli and characterized with regard to their properties in precursor protein phosphorylation. They were able to phosphorylate several chloroplast-destined precursor proteins within their cleavable presequences. In contrast, a mitochondria-destined precursor protein was not a substrate for these kinases. For all three enzymes, the phosphorylation reaction was specific for ATP with apparent Km values between 14 and 67 μm. They did not utilize other NTPs nor were those able to compete for ATP in the reaction. An excess of ADP was able to inhibit ATP-dependent phosphorylation. Furthermore, all three kinases exhibited autophosphorylation. The protein kinases described here could represent subunits of a regulatory network involved in the cytosolic events of chloroplast protein import.
Antiendotoxin activity of cationic peptide antimicrobial agents

The endotoxin from gram-negative bacteria consists of a molecule lipopolysaccharide (LPS) which can be shed by bacteria during antimicrobial therapy. A resulting syndrome, endotoxic shock, is a leading cause of death in the developed world. Thus, there is great interest in the development of antimicrobial agents which can reverse rather than promote sepsis, especially given the recent disappointing clinical performance of antiendotoxin therapies. We describe here two small cationic peptides, MBI-27 and MBI-28, which have both antiendotoxic and antibacterial activities in vitro and in vivo in animal models. We had previously demonstrated that these peptides bind to LPS with an affinity equivalent to that of polymyxin B. Consistent with this, the peptides blocked the ability of LPS and intact cells to induce the endotoxic shock mediator, tumor necrosis factor (TNF), upon incubation with the RAW 264.7 murine macrophage cell line. MBI-28 was equivalent to polymyxin B in its ability to block LPS induction of TNF by this cell line, even when added 60 min after the TNF stimulus. Furthermore, MBI-28 offered significant protection in a galactosamine-sensitized mouse model of lethal endotoxic shock. This protection correlated with the ability of MBI-28 to reduce LPS-induced circulating TNF by nearly 90% in this mouse model. Both MBI-27 and MBI-28 demonstrated antibacterial activity against gram-negative bacteria in vitro and in vivo against Pseudomonas aeruginosa infections in neutropenic mice.
Assessment of radiotherapeutic effect on brain tumors by dynamic susceptibility contrast MR imaging: a preliminary report.

PURPOSE The purpose of this study was to assess tumor vascularity of the brain by dynamic susceptibility contrast (DSC) MR imaging and to determine whether this method is clinically useful for monitoring radiation effects on brain tumors. We, furthermore, compared DSC MR imaging with single-photon emission computed tomography (SPECT) using technetium-99m diethylene-triamine-pentaacetic acid human serum albumin (99mTc-HSA-D) in the assessment of tumor vascularity in a limited numbers of cases. METHODS Twelve patients with various kinds of brain tumors were studied. DSC MRI was performed on all patients before and after radiation therapy. SPECT using 99mTc-HSA-D was also performed in five patients. The rate of change in tumor blood volume in response to radiation therapy was evaluated with DSC MRI and SPECT. The rate of change in tumor volume in response to radiation was also measured. RESULTS Ten patients were successfully studied. The rate of change in tumor blood volume correlated well between DSC MRI and SPECT. There was no significant correlation between the rates of change for tumor blood volume and tumor volume. Changes in tumor vascularity preceded the reduction in tumor volume seen following radiotherapy. CONCLUSION DSC MRI provides information regarding radiation effects on tumor vessels that is not available with conventional MRI.
Attendance , and Diverging Profiles of Substance Use and Allostatic Load in Rural African American Youth

A subset of African American youth who live in impoverished neighborhoods displays resilient profiles academically and behaviorally. We hypothesized that this resilience might be “skin deep,” in that the ongoing efforts needed to achieve success might take a physiological toll on these youth. At age 19, a total of 452 rural African American youth were assessed on broader contextual risk (neighborhood poverty) and external indicators of success (college attendance). One year later, participants were assessed on substance use and cumulative physiological risk (allostatic load). African American youth from more disadvantaged neighborhoods who attended college had lower levels of substance use but higher levels of allostatic load compared with those from less disadvantaged neighborhoods who attended college or with those who did not attend college. These findings indicate that a subset of African American youth from poor neighborhoods exhibits a profile of “skin-deep resilience” characterized by external successes combined with heightened internal physiological risk.
Timing and distribution of protein ingestion during prolonged recovery from resistance exercise alters myofibrillar protein synthesis

• A single bolus of ∼20 g of protein after a bout of resistance exercise provides a maximal anabolic stimulus during the early post‐exercise recovery period (∼5 h), but the effect of various protein feeding strategies on skeletal muscle protein synthesis during an extended recovery period (12 h) is unknown. • We compared three different patterns of ingestion of 80 g of protein during 12 h recovery after resistance exercise and the associated anabolic response in human skeletal muscle. Protein was ingested in 10, 20 or 40 g feedings using a pulsed, intermediate or bolus ingestion regimen, respectively. • Our results indicate that repeated ingestion of 20 g of protein was superior for stimulating muscle protein synthesis during the 12 h experimental period. • The three dietary treatments induced differential phosphorylation of signalling proteins and changes in mRNA abundance. • This study shows that the distribution of protein intake is an important variable to promote attainment and maintenance of peak muscle mass.
Sales Forecast in E-commerce using Convolutional Neural Network

Sales forecast is an essential task in E-commerce and has a crucial impact on making informed business decisions. It can help us to manage the workforce, cash flow and resources such as optimizing the supply chain of manufacturers etc. Sales forecast is a challenging problem in that sales is affected by many factors including promotion activities, price changes, and user preferences etc. Traditional sales forecast techniques mainly rely on historical sales data to predict future sales and their accuracies are limited. Some more recent learning-based methods capture more information in the model to improve the forecast accuracy. However, these methods require case-by-case manual feature engineering for specific commercial scenarios, which is usually a difficult, time-consuming task and requires expert knowledge. To overcome the limitations of existing methods, we propose a novel approach in this paper to learn effective features automatically from the structured data using the Convolutional Neural Network (CNN). When fed with raw log data, our approach can automatically extract effective features from that and then forecast sales using those extracted features. We test our method on a large real-world dataset from this http URL and the experimental results validate the effectiveness of our method.
Direct Sulfhydrylation for Methionine Biosynthesis in Leptospira meyeri

ABSTRACT A gene library of the Leptospira meyeri serovar semaranga strain Veldrat S.173 DNA has been constructed in a mobilizable cosmid with inserts of up to 40 kb. It was demonstrated that a Leptospira DNA fragment carrying metYcomplemented Escherichia coli strains carrying mutations inmetB. The latter gene encodes cystathionine γ-synthase, an enzyme which catalyzes the second step of the methionine biosynthetic pathway. The metY gene is 1,304 bp long and encodes a 443-amino-acid protein with a molecular mass of 45 kDa as determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The deduced amino acid sequence of theLeptospira metY product has a high degree of similarity to those of O-acetylhomoserine sulfhydrylases fromAspergillus nidulans and Saccharomyces cerevisiae. A lower degree of sequence similarity was also found with bacterial cystathionine γ-synthase. The L. meyeri metY gene was overexpressed under the control of the T7 promoter. MetY exhibits an O-acetylhomoserine sulfhydrylase activity. Genetic, enzymatic, and physiological studies reveal that the transsulfuration pathway via cystathionine does not exist in L. meyeri, in contrast to the situation found for fungi and some bacteria. Our results indicate, therefore, that the L. meyeri MetY enzyme is able to perform direct sulfhydrylation for methionine biosynthesis by using O-acetylhomoserine as a substrate.
Spatio-temporal super-resolution reconstruction based on robust optical flow and Zernike moment for dynamic image sequences

A novel and efficient spatio-temporal super-resolution reconstruction model based on robust optical flow and Zernike moment is proposed in this paper. The model does not rely on accurate estimation of subpixel motion, and is robust to noise and rotation. Moreover, it can effectively overcome the problems of block and hole artifacts in the traditional reconstruction methods. In our super-resolution process, first we propose an efficient robust optical flow motion estimation model based on the motion details protection, then introduce the bi-weighted fusion strategy to implement the spatio-temporal motion compensation, and finally apply the multi-frame information fusion scheme to make the spatio-temporal super-resolution reconstruction and optimization based on Zernike moment and non-local self-similarity. Experimental results demonstrate that the proposed method outperforms the existing methods in terms of both subjective visual and objective quantitative evaluations.
Spatial Cepstrum as a Spatial Feature Using a Distributed Microphone Array for Acoustic Scene Analysis

In this paper, with the aim of using the spatial information obtained from a distributed microphone array employed for acoustic scene analysis, we propose a robust and efficient method, which is called the spatial cepstrum. In our approach, similarly to the cepstrum, which is widely used as a spectral feature, the logarithm of the amplitude in multichannel observation is converted to a feature vector by a linear orthogonal transformation. This linear orthogonal transformation is achieved by principal component analysis (PCA) in general. Moreover, we also show that for a circularly symmetric microphone arrangement with an isotropic sound field, PCA is identical to the inverse discrete Fourier transform and the spatial cepstrum exactly corresponds to the cepstrum. The proposed approach does not require the positions of the microphones and is robust against the synchronization mismatch of channels, thus ensuring its suitability for use with a distributed microphone array. Experimental results obtained using actual environmental sounds verify the validity of our approach even when a smaller feature dimension than the original one is used, which is achieved by dimensionality reduction through PCA. Additionally, experimental results also indicate that the robustness of the proposed method is satisfactory for observations that have the synchronization mismatch of channels.
Virtual MIMO blind detection clustered WSN system

Wireless sensor network (WSN) is a energy-limited network which has lots of redundant data. This paper is based on virtual MIMO blind detection clustered wSn system and applies improved Hopfield Neural Network (HNN) blind algorithm to this system. The algorithm uses sequence with chaos initialization as the transmitting signals. In intra-cluster, we put forward double sigmoid Hopfield Neural Network (DSHNN) blind algorithm to accelerate convergence. SIC-Hopfield blind algorithm is proposed to combine advantages of virtual MIMO and HNN outside the cluster. Simulations demonstrate the superior performance of the proposed methods.
Computer Assisted Measurement of Cup Placement in Total Hip Replacement

The introduction of image guided systems in total hip replacement surgery provides the ability to plan precisely the alignment of the acetabular cup before surgery, and to perform the surgery according to the preoperative plan. Preoperative planners (interactive computer programs for surgical planning) based on three-dimensional medical images allow planning of optimal placement of implant components based on simulated implant performance. Exact measurement of the cup position during surgery allows precise placement of the cup and accurate measurement of the final position of the cup relative to the pelvis. This measurement is used to evaluate the radiographic techniques for postoperative measurement of cup alignment. Malposition of the acetabular component increases the occurrence of impingement, reduces the safe range of motion, and increases the risk of dislocation and wear. Dislocation of the implant after total hip replacement remains a significant clinical problem. Not fully understanding the interaction between pelvic orientation and final acetabular cup alignment may be one of the main contributing factors in the continued significant incidence of dislocations after total hip replacement. In this study an attempt was made to link the preoperative planning, intraoperative placement, and postoperative measurement of cup placement in total hip replacement using computer assisted techniques.
RELENTLESS AUTHENTICATION OF KEYSTROKES ON ALARMINGLY HIGH RATE ERROR ATTACKS 1

In Some network applications use authentication method to avoid the joining of malicious nodes, nevertheless, some malicious nodes could still deceive the authentication node through Snoop Forge replay attack and other means. As a result, encryption and identity authentication could not completely guarantee the safety of network, and a certain intrusion detection system is still required. Recently researchers have put forward some intrusion detection mechanisms in network, but these mechanisms generally require one or more central node to run complicated testing procedures, which result in large energy consumption and hinders its wide application in network. The result from 2640 application shows that 1) the snoop-forgereplay attacks achieve alarmingly high error rates compared to zero-effort impostor attacks, which have been the de facto standard for evaluating keystrokebased continuous verification systems; 2) four state-ofthe-art verification methods, three types of keystroke latencies, and 11 matching-pair settings (-a key parameter in continuous verification with keystrokes) that we examined in this paper were susceptible to the attack; 3) the attack is effective even when as low as 20 to 100 keystrokes were snooped to create forgeries. In light of our results, we question the security offered by current keystroke-based continuous verification systems. We point out that virtualization setup such as the one used in our experiments can also be exploited by an attacker to scale and speedup the attack.
The TibA Adhesin/Invasin from Enterotoxigenic Escherichia coli Is Self Recognizing and Induces Bacterial Aggregation and Biofilm Formation

ABSTRACT Escherichia coli strains are responsible for many cases of gastrointestinal disease and represent a serious health problem worldwide. An essential step in the pathogenesis of such strains involves recognition and attachment to host intestinal surfaces. TibA is a potent bacterial adhesin associated with a number of enterotoxigenic E. coli strains and mediates bacterial attachment to a variety of human cells; additionally, it promotes invasion of such cells. This adhesin is a surface-displayed autotransporter protein and belongs to the exclusive group of bacterial glycoproteins; only the glycosylated form confers binding to and invasion of mammalian cells. Here we characterized TibA and showed that it possesses self-association characteristics and can mediate autoaggregation of E. coli cells. We demonstrated that intercellular TibA-TibA interaction is responsible for bacterial autoaggregation. Also, TibA expression significantly enhances biofilm formation by E. coli on abiotic surfaces.