Miracle-dz/UniFAR-FTUs huggingface dataset:
Platelet Satellitism: A Culprit for Spurious Thrombocytopenia

Platelet satellitism (“adherence of platelets”) is a unique, infrequent phenomenon characterized by formation of platelet rosettes around polymorphonuclear leucocytes seen in peripheral smear prepared from EDTA-mixed blood. Platelets may interact occasionally with polymorphonuclear leucocytes forming complexes in particular conditions that may lead to spurious thrombocytopenia. This phenomenon appears to be induced or enhanced by presence of EDTA, commonly used anticoagulant. It is not associated with any definite disease process. The etiology may be immunological or non-immunological. EDTA-dependent pseudothrombocytopenia has no pathologic significance other than potentially placing a patient in jeopardy for inappropriate treatment of thrombocytopenia that does not exist.
Synthesis, properties and water permeability of SWNT buckypapers

The ability of macrocyclic ligands to facilitate formation of dispersions of single-walled carbon nanotubes (SWNTs) was investigated using a combination of absorption spectrophotometry and optical microscopy. Vacuum filtration of aqueous dispersions containing SWNTs and various macrocyclic ligands (derivatised porphyrin, phthalocyanine, cyclodextrin and calixarene) afforded self-supporting membranes known as buckypapers. Microanalytical data and energy dispersive X-ray spectra were obtained for these buckypapers and provided evidence for retention of the macrocyclic ligands within the structure of the membranes. The electrical conductivities of the membranes varied between 30 ± 20 and 220 ± 60 S cm−1, while contact angle analysis revealed they all possessed hydrophilic surfaces. The mechanical properties of buckypapers prepared using macrocyclic ligands as dispersants were shown to be comparable to that of a benchmark material prepared using the surfactant Triton X-100 (Trix). Incorporation of the macrocyclic ligands into SWNT buckypapers was found to increase their permeability up to ten-fold compared to buckypapers prepared using Trix. No correlation was observed between the water permeability of the membranes and the average size of either their surface or internal pores. However, the water permeability of the membranes was found to be inversely dependent on their surface area.
Estimation of damped oscilations using adaline network

The estimation of the frequency and damping factor of a decaying exponential is a problem of prime importance. This paper presents an algorithm based on adaptive linear neural network (Adaline) for online estimation of the frequency and damping factor of an exponentially damped sinusoidal (EDS) signal. The Adaline structure is based on a linear recursive model of the real and imaginary parts of a complex EDS signal. Using this model, the inputs of Adaline network are real damped sinusoids. The unknown parameters of signal put in the weight coefficients of the Adaline network. Normalized least mean square algorithm is applied to train the weight coefficients. The proposed method is also verified for the parameters estimation of a complex EDS signal including complex DC offset component. Convergence analysis of the proposed method is also presented. Simulation results are presented to support the desirable performance of the algorithm in different situations.
Ninjurin1 inhibits colitis-mediated colon cancer development and growth by suppression of macrophage infiltration through repression of FAK signaling

Macrophage infiltration promotes tumorigenesis. However, the macrophage infiltration regulatory molecules have not been fully determined. Nerve injury-induced protein 1 (ninjurin1) is a homophilic cell surface adhesion molecule that plays an important role in cell migration and attachment. Although ninjurin1 is believed to play a role in several malignancies, it is unclear whether ninjurin1 expression contributes to cancer progression. We used transgenic mice (tg mice) that overexpressed ninjurin1 on macrophages. We subjected ninjurin1 tg mice to a well-known mouse model of colitis-associated colon cancer in which animals are treated with azoxymethane (AOM) and dextran sulfate sodium (DSS). After AOM and DSS treatment, ninjurin1 tg mice developed fewer and smaller tumors compared with wild-type (wt) mice. Ninjurin1 tg mice also showed reduced infiltration of macrophages and suppressed angiogenesis in the tumor mass. We therefore explored whether ninjurin1 decreases macrophage migration into the tumor sites. After adoptive transfer to tumor-bearing recipients, wild type and ninjurin1 tg mice's peritoneal macrophages were freshly isolated and labeled with carboxyfluorescein succinimidyl ester (CFSE). As expected, compared with that of wt type macrophages, tumor infiltration of ninjurin1-overexpressing macrophages was significantly decreased. We also found that ninjurin1 overexpression suppressed FAK activity. In addition, knockdown of ninjurin1 enhanced FAK activity and migration activity of RAW264.7 cells. Ninjurin1 overexpression on macrophage inhibits tumor growth by suppression of macrophage infiltration through repression of FAK signaling. Ninjurin1 is a key regulator molecule for macrophage migration and Tumor-associated macrophages (TAM) mediated tumorigenesis in vivo.
A comparison of oocyte organelles in Monodelphis domestica with those of other marsupials and eutherians.

This paper reviews the current knowledge of oocyte cytology in marsupials, particularly Monodelphis domestica, and eutherian mammals. Some of the conspicuous features will be described and their function discussed. Despite many fundamental similarities between the oocytes of eutherian mammals and marsupials, some aspects are different (e.g. growth pattern, final size, timetable of cytoplasmic maturation and utilization of storage material during early cleavage stages), when most of the vesicles are extruded into the perivitelline space in marsupials.
An efficient uplink multiuser MIMO protocol in IEEE 802.11 WLANs

This paper proposes an uplink Multi-User (MU) Multiple-Input Multiple-Output (MIMO) protocol in IEEE 802.11 WLANs. In order to realize the uplink MU-MIMO transmission in 802.11 WLANs, there are several problems to be solved. Synchronized transmission among the stations (STAs) is one of the problems and the spatial compatibility between the transmitting STAs is another problem. Therefore, it is considered that many overheads are needed to realize the uplink MU-MIMO transmission. In the proposed protocol, after an access point (AP) informs the start of the uplink access phase by transmitting the indication frame, the STAs having data to be sent to the AP transmit the uplink access requests in the OFDMA manner. The AP recognizes the uplink access requests by detecting the subcarrier signals and it requests the detected STAs to transmit the pilot signals in the TDMA manner. The AP calculates the channel state information (CSI) between each STA from the received pilot signal and selects the STAs to be permitted to transmit the uplink frames based on the CSIs. The AP notifies the information about the permitted STAs and about the capable transmission rate, and then the permitted STAs simultaneously transmit the frames at the notified transmission rate. In the protocol, an efficient OFDMA-based uplink access request transmission scheme is also proposed. Thus, by adopting the proposed protocol, the overheads can be reduced and the network throughput can be enhanced. Computer simulations are performed and the results show the effectiveness of the proposed method.
An algorithm design and performance analysis for carrier-frequency offset estimation in DMB-T system

An advanced algorithm for carrier- frequency offset estimation is presented in this paper, which is based on DMB-T. The algorithm utilizes time domain difference by stages. Theoretical analysis and computer simulation prove that the algorithm has better performance than the traditional method and is able to ensure the convergence range and precision of carrier-frequency offset.
Atherogenic Indices and HDL Particle Size as Laboratory Parameters to Evaluate Cardiovascular Risk in the Presence of Dyslipidemia

Dyslipidemia may influence enzymes and transfer proteins needed to the lipoprotein particle remodeling. Calculated indices and evaluation of lipoprotein particle size have widely been used to predict cardiovascular risk. The aim of this study was to evaluate HDL particle size and LDL particle size estimate based on TG/HDL-C as well as apoB/apoA-I ratio as possible marker and atherogenic indices, respectively, of cardiovascular disease risk in the presence of dyslipidemia. We evaluated 100 individuals of both gender, without treatment with lipid-lowering drugs, 27 normolipidemic and 73 dyslipidemic, such as isolated hypercholesterolemia (n = 16), isolated hypertriglyceridemia (n = 17), low HDL-C (n = 26) and mixed dyslipidemia (n = 14). The HDL particle size did not differ between groups. The TG/HDL-C ratio was higher in groups with isolated hypertriglyceridemia (4.2 ± 1.5), low HDL-C (5.2 ± 3.1) and mixed dyslipidemia (5.3 ± 1.6). The apoB/apoA-I ratio was increased in all groups of dyslipidemia (apoB/apoA-I > 0.5) when compared to normolipidemic (apoB/apoA-I = 0.5, p
Structural VARs and DSGE models: applications to macroeconomics

Los argumentos de la tesis son los modelos VAR estructurales y los modelos dinamicos de equilibrio general ambos aplicados a la macroeconomia. El primer capitulo analiza, por medio de modelos VAR, los efectos de la politicas monetaria y fiscal sobre el producto interior bruto (PIB) y el nivel de los precios en la economia norteamericana a partir de los anos sesenta. Ambas politicas producen efectos pequenos. El capitulo demuestra que si en un modelo VAR para el analisis solo de la politica monetaria se incluyen variables fiscales, sus efectos se educen de la mitad. El segundo capitulo analiza los efectos de aumentos de los tipos de interes a corto plazo sobre los indices de bolsas en los paises que forman el G-7 y en Espana. Los efectos, en general negativos y transitorios, son diferentes en termino de reduccion de los indices entre los paises analizados. Variaciones exogenas de los tipos de interes no parecen ser responsables de los principales movimientos en los indices de bolsa. El tercer capitulo presenta un modelo de equilibrio economico general en el cual las familias consumidoras pueden invertir en acciones y en depositos bancarios. El modelo, calibrado sobre los datos de la economia norteamericana es capaz de reproducir, desde un punto de vista cualitativo, los efectos de la politica monetaria sobre el indice de la bolsa. El ultimo capitulo confronta tres modelos de equilibrio economico general alternativos del ciclo economico. En el primero las fricciones financieras determinan endogenamente costes para variar el nivel de capital. En los otros dos estos costes son exogenos. Los modelos son estimados mediante el metodo de la maxima verosimilitud utilizando datos sobre la economia norteamericana de 1966 hasta el 2001. El resultado principal es que el primer modelo no parece explicar mejor que los modelos alternativos las dinamicas de las principales variables del modelo.
Extracting Dependencies from Software Changes: An Industry Experience Report

Retrieving and analyzing information from software repositories and detecting dependencies are important tasks supporting software evolution. Dependency information is used for change impact analysis, defect prediction as well as cohesion and coupling measurement. In this paper we report our experience from extracting dependency information from the change history of a commercial software system. We analyzed the software system's evolution of about six years, from the start of development to the transition to product releases and maintenance. Analyzing the co-evolution of software artifacts allows detecting logical dependencies between system parts implemented with heterogeneous technologies as well as between different types of development artifacts such as source code, data models or documentation. However, the quality of the extracted dependencies relies on established development practices and conformance to a defined change process. In this paper we indicate resulting limitations and recommend further processing and filtering steps to prepare the dependency data for subsequent analysis and measurement activities.
The immunochemistry of Staphylococcus aureus mucopeptide. I. Antigenic specificity of the peptide subunits.

Antigenic determinants of Staphylococcus aureus mucopeptide and corresponding antibodies in rabbit antiserum have been studied, using synthetic peptides in inhibition of indirect haemagglutination and immunoadsorbent techniques. Results are presented to show that at least 3 determinants are present in the peptide subunits. The pentapeptide L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala exhibits 2 determinants, one of which is located to the C-terminal D-Ala-D-Ala, and the penta-glycine bridge one determinant.
Hal: an Automated Pipeline for Phylogenetic Analyses of Genomic Data

The rapid increase in genomic and genome-scale data is resulting in unprecedented levels of discrete sequence data available for phylogenetic analyses. Major analytical impasses exist, however, prior to analyzing these data with existing phylogenetic software. Obstacles include the management of large data sets without standardized naming conventions, identification and filtering of orthologous clusters of proteins or genes, and the assembly of alignments of orthologous sequence data into individual and concatenated super alignments. Here we report the production of an automated pipeline, Hal that produces multiple alignments and trees from genomic data. These alignments can be produced by a choice of four alignment programs and analyzed by a variety of phylogenetic programs. In short, the Hal pipeline connects the programs BLASTP, MCL, user specified alignment programs, GBlocks, ProtTest and user specified phylogenetic programs to produce species trees. The script is available at sourceforge (http://sourceforge.net/projects/bio-hal/). The results from an example analysis of Kingdom Fungi are briefly discussed.
RecA+-Dependent Repair of Gamma-Ray Damage to Escherichia coli Does Not Require Recombination Between Existing Homologous Chromosomes

Chemostat-grown Escherichia coli showed recA+-dependent resistance to gamma radiation even though between 50 and 75% of the population possessed only a single unreplicated genome, suggesting that recombination between homologous chromosomes before replication is not necessary for manifestation of recA+-dependent resistance to gamma radiation.
Carbon stars with increased oxygen and nitrogen abundances: hydrostatic dust-free model atmospheres

We have computed a grid of hydrostatic spherical COMARCS models for C stars covering metallicities from [Z/H]=0 to -2 and values of the carbon excess [C-O] from 6.41 to 9.15, plus some temperature sequences, where the amount of oxygen and nitrogen is increased relative to a scaled solar element mixture. Such abundance variations may appear during the late stages of stellar evolution. Our study covers changes of [O/Z] and [N/Z] going up to +0.5. Based on the atmospheric structures we have calculated synthetic spectra and photometry for all of the models in a consistent way. The sequences with changed [O/Z] and [N/Z] can be used to derive correction terms, which are applied to the colours predicted for a certain combination of effective temperature, surface gravity, metallicity and carbon excess. If one neglects these shifts in case of a variable oxygen amount, taking [C-O] instead of C/O gives much better results, since the first quantity dominates the formation of many important molecular species. For the warmer C giants with weaker pulsation it is in principle possible to determine [C-O], [O/Z] or [N/Z] from high resolution spectra, when the opacities in the radiative transfer calculations for the models and observable properties are treated consistently. The corresponding changes due to the abundances often become significantly larger than the deviations caused by uncertainties of the stellar parameters or by a optically thin dust shell. Photometric data and low or medium resolution spectra are not sufficient to derive the mentioned quantities.
Visualization of DTI fibers using hair-rendering techniques

Diffusion Tensor Imaging (DTI) is an MRI technique that measures the diffusion of water in tissue such as white matter and muscle. From a DTI dataset, tracts representing fibers in the data can be reconstructed. Because of the vast amounts of fibers that can be reconstructed from a dataset, the visualization of these fibers is a challenging problem. In order to give the user a better understanding of the structure of the data, it is necessary to convey both the shapes of fibers, and the mutual coherency among multiple fibers and groups of fibers. Besides the fibers that were reconstructed, the local tensor properties, such as the second and third eigendirections and eigenvalues, are also of importance. We propose to use line illumination and shadowing of fibers in order to improve the perception of their structure. We also present a new method, inspired by the modeling of curled hair, for showing extra tensor properties along the fibers. This is done by showing curves that spirally wind around the actual fiber location, where the local tensor determines the parameters of that curve. We implemented the illumination, shadowing, and spiral curves, in such a way that the user can interact with the data and interactively change all parameters. The presented methods help in gaining more insight in DTI data of the brain and the heart. It is now possible to visualize more dense fiber structures using lighting and shadowing. The spiral curves help in evaluating the data where the extra tensor properties are of importance.
Broad-band reflection spectroscopy of MAXI J1535–571 using AstroSat: estimation of black hole mass and spin

We report the results from \textit{AstroSat} observations of the transient Galactic black hole X-ray binary MAXI J1535-571 during its hard-intermediate state of the 2017 outburst. We systematically study the individual and joint spectra from two simultaneously observing \textit{AstroSat} X-ray instruments, and probe and measure a number of parameter values of accretion disc, corona and reflection from the disc in the system using models with generally increasing complexities. Using our broadband ($1.3-70$ keV) X-ray spectrum, we clearly show that a soft X-ray instrument, which works below $\sim 10-12$ keV, alone cannot correctly characterize the Comptonizing component from the corona, thus highlighting the importance of broadband spectral analysis. By fitting the reflection spectrum with the latest version of the \textsc{relxill} family of relativistic reflection models, we constrain the black hole's dimensionless spin parameter to be $0.67^{+0.16}_{-0.04}$. We also jointly use the reflection spectral component (\textsc{relxill}) and a general relativistic thin disc component (\texttt{Kerrbb}), and estimate the black hole's mass and distance to be $10. 39_{-0.62}^{+0.61} M_{\odot}$ and $5. 4_{-1.1}^{+1.8}$ kpc respectively.
Fuel Cell System Based On Boost Inverter For Single Phase Grid Integration Using ANN

Alternative energy sources, such as solar and fuel cells are desirable due to their pollution-free property. To utilize the current infrastructure of the grid for power transmission and distribution, grid-connected dc-to-ac inverters are needed.When a low-voltage unregulated fuel-cell (FC) output is conditioned to generate the ac power, two stages are required: a boost stage and an inversion one. Here the boost-inverter topology that achieves both boosting and inversion functions in a single-stage is used as a building block. It is used to develop a single-phase gridconnected FC-system which offers high conversion efficiency, low-cost and compactness.In addition, this system incorporates battery-based energy storage and a bidirectional dc-dc converter to support the slow dynamics of FC. The single-phase boost inverter is voltage-mode controlled and the bidirectional dc-dc converter is current-mode controlled. Artificial neural network is used here as the controller. The battery supplies the lowfrequency current ripple which minimizes the effects of such ripple being drawn directly from the FC itself. Also, this system can operate either in a grid-connected or stand-alone mode. Simulation results are presented to confirm the performance of the proposed system. Keywords—Boost inverter, fuel cell(FC), grid-connected inverter, PQ control
Differential Expression Patterns of c-REL Protein in Classic and Nodular Lymphocyte Predominant Hodgkin Lymphoma

Classic Hodgkin lymphoma (cHL) is characterized by numerical gains of the short arm of chromosome 2. The high frequency of 2p overrepresentation including REL, particularly in the nodular sclerosis subtype suggests that constitutive activation of nuclear factor κB/REL is a hallmark of Reed-Sternberg (RS) cells. The aim of this study was to investigate c-Rel protein expression patterns in cHL and nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) cases by immunohistochemical analysis. A total of 79 cases of HL were analyzed, which included 59 cases of cHL (49 nodular sclerosis; 8 mixed cellularity; 2 lymphocyte-rich) and 20 cases of NLPHL. Positive staining was defined in this study as a reaction seen in the nuclei or nuclei and cytoplasm of RS or lymphocytic and histiocytic (L&H) cells in cHL and NLPHL cases, respectively. The percent positivity of c-REL staining of RS cells in cHL was seen in 51 of 59 cases (86.4%). No significant difference in c-REL expression was seen between nodular sclerosis (42 of 49, 85.7%) and mixed cellularity subtypes (7 of 8 cases, 87.5%; P = 1). In comparison, positive c-REL protein expression in L&H cells was seen in 5 of 20 NLPHL cases (25.0%). Therefore, significantly higher positivity of RS cells in cHL was seen compared with positivity of L&H cells in NLPHL; 86.4% vs. 25.0%; P = 0). Expression of Epstein-Barr virus latent membrane protein was seen in 6 of 30 cases (19.0%; 25 cHL, 5 NLPHL) and EBER1 in 5 of 27 cases (18.5%; 24 cHL, 3 NLPHL). The presence of Epstein-Barr virus did not correlate with c-REL protein expression (P = 1). Our results demonstrate that there is differential c-REL protein expression in cHL in comparison with NLPHL and suggest that c-REL may play a role in the pathogenesis of classic Hodgkin lymphoma.
A Rendering Algorithm for Discrete Volume Density Objects

We present a new algorithm for simulating the effect of light travelling through volume objects. Such objects (haze, fog, clouds…) are usually modelized by voxel grids which define their density distribution in a discrete tridimensional space. The method we propose is a two‐pass Monte‐Carlo ray‐tracing algorithm that does not make any restrictive assumptions neither about the characteristics of the objects (both arbitrary density distributions and phase functions are allowed) nor about the physical phenomena included in the rendering process (multiple scattering is accounted for). The driving idea of the algorithm is to use the phase function for Monte‐Carlo sampling, in order to modify the direction of the ray during scattering.