Miracle-dz/UniFAR-FTUs huggingface dataset:
Exploiting social influence for context-aware event recommendation in event-based social networks

Event-based Social Networks (EBSNs) which bridge the gap between online and offline interactions among users have received increasing popularity. The unique cold-start nature makes event recommendation more challenging than traditional recommendation problems, since even for two events with the same content, they may not happen at the same time, the same location, or be organized by the same host. Existing event recommendation algorithms mainly exploit the basic context information (e.g., location, time and content), while the social influence of event hosts and group members have been ignored. In this paper, we propose a Social Information Augmented Recommender System (SIARS), which fully exploits the social influence of event hosts and group members together with basic context information for event recommendation. In particular, we combine the information of EBSNs and other social networks to characterize the social influence of event hosts, and take interactions between group members into consideration for event recommendation. In addition, we propose a new content-aware recommendation model using the topic model to find the most similar topic the event belongs to, and a new location-aware recommendation model integrating location popularity with location distribution for event recommendation. Extensive experiments on real-world datasets demonstrate that SIARS outperforms other recommendation algorithms.
Application Of Fast Filter Bank For Transcription Of Polyphonic Signals

In this paper, a novel approach to the transcription of polyphonic signals is investigated. The method makes use of top–down analysis algorithm and bottom–up reconstruction of frequency contents of musical signals using a reference database that contains the spectral profiles of all single notes. Recognition accuracy is enhanced by analyzing the time-frequency contents using a bank of narrow band filters with very sharp transition band. The filters are designed using the Frequency-Response Masking technique. The high selectivity of the filters has enhanced the frequency analysis and increased the accuracy of identification. The method was tested with musical notes generated from an acoustic piano. The results show that for single notes and chords up to four notes, perfect identification can be achieved.
Current alcohol use is associated with a reduced risk of hot flashes in midlife women.

AIMS To examine the relation between current alcohol use, estradiol, estrone, and testosterone levels, and hot flashes in midlife women using a case-control study design. METHODS Cases were midlife women (45-54 years) who reported ever experiencing hot flashes. Controls were midlife women (45-54 years) who reported never experiencing hot flashes. Each participant completed a questionnaire and provided a blood sample that was used to measure estradiol, estrone, and testosterone levels by enzyme-linked immunosorbent assay. RESULTS The results indicate that current alcohol use (at least one day per month) was significantly associated with a reduced risk of hot flashes compared to non-use of alcohol, independent of age and smoking habits. The hot flashes experienced by current alcohol users were less severe and less frequent than those experienced by non-users of alcohol. Further, current alcohol users had similar levels of estradiol, estrone, and testosterone compared to non-users of alcohol. CONCLUSIONS These data suggest that current alcohol use is associated with a reduced risk of any, severe, and frequent hot flashes in midlife women by a mechanism that may not include changes in sex steroid hormone levels.
Unique requirements for social science human subjects research within the United States Department of Defense

Although most researchers are familiar with the application of the Common Rule in research, fewer are aware of specific requirements and restrictions for conducting human subjects research when employees of the US Department of Defense (DoD) will be participants. Because of the additional regulations concerning DoD employees as participants, federal regulations and research policies require researchers to submit their human subjects research proposals through a DoD review process to ensure compliance with DoD research policies, regardless of a non-DoD IRB’s approval. These research policies recognize the vulnerability of military subjects within a hierarchical organization to potential coercion and abuse during research studies. This article describes some of the unique requirements to conduct human subjects research within the DoD (in which the participants are military or civilian). The article concludes with steps researchers can follow to facilitate the DoD review process for research, and timely research within the DoD.
Multiple Antigen-Specific Processing Pathways for Activating Naive CD8+ T Cells In Vivo

Current knowledge of the processing of viral Ags into MHC class I-associated ligands is based almost completely on in vitro studies using nonprofessional APCs (pAPCs). This is two steps removed from real immune responses to pathogens and vaccines, in which pAPCs activate naive CD8+ T cells in vivo. Rational vaccine design requires answers to numerous questions surrounding the function of pAPCs in vivo, including their abilities to process and present peptides derived from endogenous and exogenous viral Ags. In the present study, we characterize the in vivo dependence of Ag presentation on the expression of TAP by testing the immunogenicity of model Ags synthesized by recombinant vaccinia viruses in TAP1−/− mice. We show that the efficiency of TAP-independent presentation in vitro correlates with TAP-independent activation of naive T cells in vivo and provide the first in vivo evidence for proteolytic processing of antigenic peptides in the secretory pathway. There was, however, a clear exception to this correlation; although the presentation of the minimal SIINFEKL determinant from chicken egg OVA in vitro was strictly TAP dependent, it was presented in a TAP-independent manner in vivo. In vivo presentation of the same peptide from a fusion protein retained its TAP dependence. These results show that determinant-specific processing pathways exist in vivo for the generation of antiviral T cell responses. We present additional findings that point to cross-priming as the likely mechanism for these protein-specific differences.
Immune parameters in multiple myeloma patients: influence of treatment and correlation with opportunistic infections

The present study evaluated cellular and humoral immune parameters in myeloma patients, focusing on the effect of treatment and the risk of opportunistic infections. Peripheral blood lymphocyte subsets and serum levels of nonmyeloma immunoglobulins (Ig) were analysed in 480 blood samples from 77 myeloma patients. Untreated myeloma patients exhibited significantly reduced CD4+/45RO+, CD19+, CD3+/HLA-DR+, and natural killer (NK) cells, as well as nonmyeloma IgA, IgG and IgM. Conventional-dose chemotherapy resulted in significantly reduced CD4+ and even further decline of CD4+/CD45RO+ and CD19+ cells, most notably in relapsed patients. Additional thalidomide treatment had no significant effects on these parameters. Following high-dose chemotherapy (HD-CTX), prolonged immunosuppression was observed. Although CD8+, NK, CD19+ and CD+/CD45RO+ cells recovered to normal values within 60, 90, 360 and 720 days, respectively, CD4+ counts remained reduced even thereafter. Nine opportunistic infections were observed, including five cytomegalovirus (CMV) diseases, one Pneumocystis carinii pneumonia (PCP) and three varicella zoster virus infections with CMV diseases and PCP occurring exclusively after HD-CTX. Opportunistic infections were correlated with severely reduced CD4+, as well as CD4+/CD45RO+ and CD19+ counts. Thus, myeloma patients display cellular and humoral immunodeficiencies, which increase following conventional as well as HD-CTX, and constitute an important predisposing factor for opportunistic infections.
Functional Decomposition for Bundled Simplification of Trail Sets

Bundling visually aggregates curves to reduce clutter and help finding important patterns in trail-sets or graph drawings. We propose a new approach to bundling based on functional decomposition of the underling dataset. We recover the functional nature of the curves by representing them as linear combinations of piecewise-polynomial basis functions with associated expansion coefficients. Next, we express all curves in a given cluster in terms of a centroid curve and a complementary term, via a set of so-called principal component functions. Based on the above, we propose a two-fold contribution: First, we use cluster centroids to design a new bundling method for 2D and 3D curve-sets. Secondly, we deform the cluster centroids and generate new curves along them, which enables us to modify the underlying data in a statistically-controlled way via its simplified (bundled) view. We demonstrate our method by applications on real-world 2D and 3D datasets for graph bundling, trajectory analysis, and vector field and tensor field visualization.
Associated factors for REM sleep behavior disorder in Parkinson disease

Objective: To investigate the frequency, phenomenology, and associated risk factors of REM sleep behavior disorder (RBD) in Parkinson disease (PD). Methods: An unselected cohort of sleep-disturbed patients with PD (n=457) was investigated with video-supported polysomnography. We determined the frequency of RBD and analyzed the influence of age, clinical disease features, disease duration, cognitive and physical impairment, medication, comorbidity, and sleep architecture. Results: The overall frequency of RBD was 46%. According to our cohort and modified definition, there was no preferred PD subtype for RBD (p=0.142). There was no gender preference (p=0.770). RBD was associated with older age (p=0.000). Adjusted for age and gender, patients with PD and RBD had longer disease duration (p=0.024), higher Hoehn & Yahr stages (p=0.002), more falls (p=0.018), more fluctuations (p=0.005), more psychiatric comorbidity (p=0.026), and a higher dose of levodopa (p=0.002). The presence of RBD was related to slightly increased sleep efficiency (p=0.007), a higher amount of REM sleep (p=0.000), and more periodic leg movements during sleep (p=0.019). Conclusion: RBD is a frequent and clinically relevant nocturnal disturbance for all stages of PD. It increases with age and disease duration and may contribute to the nocturnal problems of patients with PD and their bed partners.
The effect of duration of stretching of the hamstring muscle group for increasing range of motion in people aged 65 years or older.

BACKGROUND AND PURPOSE Stretching protocols for elderly people (> or = 65 years of age) have not been studied to determine the effectiveness of increasing range of motion (ROM). The purpose of this study was to determine which of 3 durations of stretches would produce and maintain the greatest gains in knee extension ROM with the femur held at 90 degrees of hip flexion in a group of elderly individuals. SUBJECTS Sixty-two subjects (mean age = 84.7 years, SD = 5.6, range = 65-97) with tight hamstring muscles (defined as the inability to extend the knee to less than 20 degrees of knee flexion) participated. Subjects were recruited from a retirement housing complex and were independent in activities of daily living. METHODS Subjects were randomly assigned to 1 of 4 groups and completed a physical activity questionnaire. The subjects in group 1 (n = 13, mean age = 85.1 years, SD = 6.4, range = 70-97), a control group, performed no stretching. The randomly selected right or left limb of subjects in group 2 (n = 17, mean age = 85.5 years, SD = 4.5, range = 80-93), group 3 (n = 15, mean age = 85.2 years, SD = 6.5, range = 65-92), and group 4 (n = 17, mean age = 83.2 years, SD = 4.6, range = 68-90) was stretched 5 times per week for 6 weeks for 15, 30, and 60 seconds, respectively. Range of motion was measured once a week for 10 weeks to determine the treatment and residual effects. Data were analyzed using a growth curve model. RESULTS A 60-second stretch produced a greater rate of gains in ROM (60-second stretch = 2.4 degrees per week, 30-second stretch = 1.3 degrees per week, 15-second stretch = 0.6 degrees per week), which persisted longer than the gains in any other group (group 4 still had 5.4 degrees more ROM 4 weeks after treatment than at pretest as compared with 0.7 degrees and 0.8 degrees for groups 2 and 3, respectively). DISCUSSION AND CONCLUSION Longer hold times during stretching of the hamstring muscles resulted in a greater rate of gains in ROM and a more sustained increase in ROM in elderly subjects. These results may differ from those of studies performed with younger populations because of age-related physiologic changes.
Adapting multi-agent systems approach for integration of prosumers in Smart Grids

Massive deployment of distributed energy resources, predominately renewable, is expected to be a general trend in the near future. Integration of such elements in distribution grid represents one of key challenges that Smart Grids will have to face with. In this work we aim at bridging industrial and academic views on future trends in this field. We list main issues to be tackled and we propose a conceptual system-level solution based on Multi-Agent Systems. We show basic functionalities and structure for supporting ICT architecture.
A Distributed Control Framework for Integrated Photovoltaic-Battery-Based Islanded Microgrids

This paper proposes a new cooperative control framework for coordination of energy storage units (ESUs), photovoltaic (PV) panels, and controllable load units in single-phase low voltage microgrids (MGs). The control objectives are defined and acted upon using a two level structure; primary and secondary control. Unlike conventional methods, a V–I droop mechanism is utilized in the primary control level. A distributed strategy is introduced for the secondary control level to regulate the MG voltage and manage state of charge (SoC) and power among the ESUs. The distributed secondary controllers are coordinated based on a leader-follower framework, where the leader restores the MG voltage to the rated value and the followers manage the sharing of power between the ESUs so as to balance the SoCs. Once the ESUs reach the minimum charge level, the information state increases above a positive critical value, at which point load control units perform load shedding. Similarly, fair PV curtailment is conducted in case the ESUs reach the maximum charge level. Experimental results are presented to demonstrate the efficacy of the proposed method.
Routine Isotropic Computed Tomography Scanning of Chest: Value of Coronal and Sagittal Reformations

Objective: We sought to evaluate the usefulness of coronal and sagittal reformations from isotropic chest computed tomography (CT) examinations. Methods: A total of 30 chest CT examinations were reconstructed into 2 sets of axial source images: 0.9-mm slice width with 0.45-mm reconstruction interval (isotropic) and 4-mm slices with 3-mm reconstruction interval. The isotropic dataset was reformatted into coronal and sagittal stacks with 4-mm slices. Three readers reviewed the image sets with 4-mm slice widths. Coronal and sagittal reformations were compared at the same sitting to axial images for depiction of anatomy and disease in the aorta, pulmonary arteries, hilar regions, mediastinum, lung parenchyma, pleura, diaphragm, thoracic spine, ribs, and trachea. A 5-point scale was used to determine whether nonaxial reformations showed anatomy and disease significantly better, somewhat better, same, somewhat worse or significantly worse than equivalent thickness axial source images. A 3-point scale was used to score if nonaxial image sets showed no, some, or significant additional information compared with the axial plane regarding the main diagnosis. Results: There was better visualization of the hilar regions, diaphragm, spine, and trachea on the coronal reformations compared with source axial images (P < 0.05). Sagittal reformations scored better than axial source images for aorta, pleura, diaphragm, spine, and ribs (P < 0.05). The coronal and sagittal series showed significant additional information in 11% and 9% of patients, respectively. Conclusion: Radiologists should consider the use of one or both of coronal and sagittal planes in addition to the axial series in routine interpretation of chest CT.
Where Cultural Competency Begins: Changes in Undergraduate Students' Intercultural Competency

Teacher preparation programs and accreditation organizations have acknowledged need for educators to demonstrate intercultural knowledge, skills, and abilities. Teacher educators are responding to emphasis in higher education to assure that graduates achieve intercultural competence (NCATE, 2008). This study compared the cultural competency of university students before and after participation in domestic intensive and intentional cross-cultural undergraduate courses. Data analysis showed that undergraduate students began their classes at the same levels of intercultural competence, with ethnocentric views that minimize cultural differences between themselves and others. Students usually began with over-estimating their intercultural competence. However, their actual developmental orientation toward cultural differences was more ethno-centric. Due to their lack of experience among people of cultures different than their own, they were more likely to minimize cultural differences and emphasize cultural commonalities. During this investigation, after the first semester, data analysis showed no statistically significant change in students’ cultural competence. After a semester with higher-impact activities (e.g., cultural partnerships), subjects showed statistically significant positive gains in their orientations to cultures different than their own. Investigators concluded that domestic inter-cultural experiences may encourage university students to not only learn about others, but also learn from and with others.
Youth labour market integration in Spain: Search time, job duration and skill mismatch

In recent years young workers in Spain have had great difficulties in finding and maintaining a job. Furthermore, the early histories of new entrants into the Spanish labour market has typically involved young workers accepting jobs for which the required level of education is lower that the attained level. Using the ad hoc module of the Labour Force Survey (2nd quarter, 2000), in this paper I analyse the transition from school to work for a sample of Spanish youths who left education for the first time after 1990. I allow the search period after completing education, the duration of the first significant job, and the probability of being over-educated in that job to be correlated in a system of simultaneous equations which is estimated by maximum likelihood. The results suggest that over-educated workers experience shorter durations in their first significant job. I do not find a direct effect of search time on employment duration. However, there are unobserved factors that increase the first unemployed job search period after completing education, and that also increase the subsequent employment duration.
Bronchoalveolar lavage cellularity. The distribution in normal volunteers.

Bronchoalveolar lavage (BAL) is used to obtain inflammatory cells from the lung. For clinical research, parametric statistics are frequently used to compare cells present in BAL of patients with lung disease with cells present in BAL of normal subjects. To determine if these populations can be compared in this manner we performed BAL on 111 never-smoking, normal volunteers and determined: (1) the mean, median, standard deviation, and range of the cells in BAL; (2) whether the data are normally distributed and satisfy the criteria for use of parametric statistical analysis. The BAL cellularity was expressed as a percentage of total cells, cells per milliliter return, and total cells per lavage. Regardless of the means of expression, no measure of BAL cellularity (total cells, macrophages, lymphocytes, neutrophils, or eosinophils) conformed to the normal (bell-shaped) distribution when tested for goodness of fit with the G statistic (all p < 0.001). The lack of fit to the normal distribution was not substantially altered by either the method of expressing the data (i.e., cells per milliliter, total cells, or percent of cells) or log transformation of the data. The poor fit in all cases resulted from clumping of the data about the mean and large tails. The percent of cells were, therefore, tested for goodness of fit to the Poisson distribution, a distribution of discrete variables. The neutrophil and eosinophil percentages resulted in an excellent fit to the Poisson distribution, but macrophage and lymphocyte percentages did not. (ABSTRACT TRUNCATED AT 250 WORDS)
Prediction of software reliability using neural networks

Software reliability growth models have achieved considerable importance in estimating reliability of software products. The authors explore the use of feed-forward neural networks as a model for software reliability growth prediction. To empirically evaluate the predictive capability of this new approach, data sets from different software projects are used. The neural networks approach exhibits a consistent behavior in prediction and the predictive performance is comparable to that of parametric models. <<ETX>>
Sliding doors in Brussels: A career path analysis of EU affairs managers

This article investigates the revolving doors phenomenon in the European Union (EU). It proposes a management approach that treats this phenomenon as a form of corporate political activity through which companies try to gain access to decision makers. By using sequence analysis to examine the career paths of almost 300 EU affairs managers based in public and private companies across 26 countries, three different ideal-typical managers are identified: those EU affairs managers coming from EU institutions and public affairs; those who make a career through the private sector; and those who establish themselves in national political institutions. This identification confirms that EU institutions need different types of information and companies need EU affairs managers with different professional backgrounds able to provide it. Rather than observing a revolving door of EU officials into EU government affairs, what the authors term ‘sliding doors’ – namely the separation of careers, especially between the public and private sectors – is discerned.
Comparison of enzyme-linked immunosorbent and indirect hemagglutination assays for determining anthrax antibodies

An enzyme-linked immunosorbent assay has been established to measure anthrax antibody titers. The protective antigen component of anthrax toxin was used as the capture antigen. Two types of conjugates (protein A-horseradish peroxidase and anti-human immunoglobulin G plus immunoglobulin A plus immunoglobulin M-horseradish peroxidase) were tested. Results from enzyme-linked immunosorbent assay testing were compared with those from indirect hemagglutination titers on serum from vaccinees. The overall trend of enzyme-linked immunosorbent assay and indirect hemagglutination titers was significant. The enzyme-linked immunosorbent assay offered speed, precision, and reduced cost per test.