Miracle-dz/UniFAR-FTUs huggingface dataset:
Measuring the added value of haptic feedback

While there is an increased appreciation for integrating haptic feedback with audio-visual content, there is still a lack of understanding of how to quantify the added value of touch for a user's experience (UX) of multimedia content. Here we focus on three main concepts to measure this added value: UX, emotions, and expectations. We present a case study measuring the added value of haptic feedback for a standardized set of audio-visual content (i.e., short video clips), comparing two haptic stimulation modalities (i.e., mid-air vs. vibro-tactile stimuli). Our findings demonstrate that UX of haptically-enhanced audio-visual content is perceived as a more pleasant, unpredictable, and creative experience. The users' overall liking increases together with a positive change of the users' expectations, independently from the haptic stimulation modality. We discuss how our approach provides the foundation for future work on developing a measurement model to predict the added value of haptic feedback for users' experiences within and beyond the multimedia context.
Genomic rearrangements at the BRCA1 locus in Spanish families with breast/ovarian cancer.

BACKGROUND Large genomic rearrangements (LGRs) account for a substantial proportion of the BRCA1 disease-causing changes, or variations, identified in families with hereditary breast/ovarian cancer [HB(O)C]. Great differences in the spectrum and prevalence of BRCA1 LGR have been observed among populations. Here we report the first comprehensive analysis of BRCA1 LGRs conducted in Spain. METHODS We used multiplex ligation-dependent probe amplification (MLPA) to screen for BRCA1 LGRs in the index case individuals of 384 HB(O)C families who previously tested negative for BRCA1 and BRCA2 point variations, small insertions, and deletions. An alternative set of MLPA probes, long-range PCR, and real-time PCR were used to confirm positive results. RESULTS We have identified 8 different BRCA1 rearrangements (del exon 1-24, del exon 8-13, del exon 11-15, del exon 14, dup exon 19-20, dup exon 20, exon 21-22 amplification, and del exon 23-24). With the exception of del exon 8-13, they are novel alterations. Overall, BRCA1 LGRs explain 1.4% of the Spanish HB(O)C families, and they account for 8.2% of all BRCA1 pathogenic variations identified in our study population. BRCA1 genetic variants affecting hybridization of commercially available MLPA probes are very rare in our population. CONCLUSIONS Screening for BRCA1 LGRs should be mandatory in Spanish HB(O)C families. A high proportion of country-specific rearrangements are scattered along the gene. MLPA is a robust method to screen for LGRs in our population. MLPA analysis of positive samples with an alternative set of probes, together with long-range PCR and real-time PCR, is a feasible approach to confirm results in cases in which LGR breakpoints have not been characterized.
Extended beamforming by sum and difference composite co-array for radio surveillance

This paper presents a way of extended digital beamforming technique by non-uniform array antenna used for radio surveillance. We try to enhance the array degree of freedom (DOF) by combining the concepts of extended (sum and difference) co-arrays, so that we can create a better beampattern with narrower mainbeam and more number of nulls. Performance of the proposed array configuration is evaluated through computer simulation of digital beamforming. We also study the way of modulation/demodulation which is effective for the extended arrays.
Analysis for Association between Genomic Information and Survival Rate of Glioblastoma Multiforme

In order to combat cancer, more and more efforts have been made in genome studies, as cancer is likely to be caused by errors in DNA that let the cells grow uncontrolled. Glioblastoma multiforme (GBM) is the most aggressive malignant brain tumor, and it has a very low survival rate of about one year [1]. It is significant, if some relationship can be found between the survival rate of GBM patients and the genome information. The Cancer Genome Atlas (TCGA) project collects tumor tissue donated by cancer patients. The TCGA data contains clinical information, genomic characterization data and high-throughput sequencing analysis of the tumor genomes [2].
W-Band Fresnel Zone Plate Reflector for Helicopter Collision Avoidance Radar

A high gain Fresnel zone plate reflector is presented for helicopter collision avoidance radar at 94 GHz. The antenna system consists of a compact, airtightness and low return loss primary source illuminating a printed reflector with Fresnel plate zone phase correction. In order to increase the overall efficiency, the reflector combines 8 correcting zones in its center and 4 on the border. Reflected phase of over 360deg is achieved by means of circular ring or combined circular and ring patches. The reflector is fabricated using standard photolithographic techniques. The primary source consists of a small FSS made by a double slot array antenna pasted on the aperture of a standard WR-10 waveguide. Antenna measurements were conducted using a compact base arrangement. The antenna performs 37.8 dBi at the center frequency of 94 GHz with a maximum value of the return loss value not exceeding -25 dB. The frequency bandwidth at -3 dB in gain and return loss is of 9%
S.O.S.: Does Your Search Engine Results Page (SERP) Need Help?

Over the past 20 years, search engines have become emph{the} entry point of the WWW. Due to evolving needs for different and new kinds of information, the interfaces of search engine results pages (SERPs) change over time. Thus, their usability must be continuously evaluated to ensure user satisfaction and competitive edge. As no complete solution exists, we present emph{S.O. S. :} the emph{SERP Optimization Suite}. Our approach comprises (a) emph{WaPPU}, which is a near real-time tool for evaluating web interfaces based on usability scores, and (b) a emph{catalog of best practices} that maps bad scores to potential causes and corresponding adjustments for optimization. During a case study in which we assessed and optimized a real-world SERP, S.O. S. has proven its feasibility and effectiveness by significantly improving the SERP's usability.
Spatiotemporal Dynamics of Attention Networks Revealed by Representational Similarity Analysis of EEG and fMRI

The fronto-parietal attention networks have been extensively studied with functional magnetic resonance imaging (fMRI), but spatiotemporal dynamics of these networks are not well understood. We measured event-related potentials (ERPs) with electroencephalography (EEG) and collected fMRI data from identical experiments where participants performed visual and auditory discrimination tasks separately or simultaneously and with or without distractors. To overcome the low temporal resolution of fMRI, we used a novel ERP-based application of multivariate representational similarity analysis (RSA) to parse time-averaged fMRI pattern activity into distinct spatial maps that each corresponded, in representational structure, to a short temporal ERP segment. Discriminant analysis of ERP-fMRI correlations revealed 8 cortical networks-2 sensory, 3 attention, and 3 other-segregated by 4 orthogonal, temporally multifaceted and spatially distributed functions. We interpret these functions as 4 spatiotemporal components of attention: modality-dependent and stimulus-driven orienting, top-down control, mode transition, and response preparation, selection and execution.
Fast 3-D fingertip reconstruction using a single two-view structured light acquisition

Current contactless fingertip recognition systems based on three-dimensional finger models mostly use multiple views (N > 2) or structured light illumination with multiple patterns projected over a period of time. In this paper, we present a novel methodology able to obtain a fast and accurate three-dimensional reconstruction of the fingertip by using a single two-view acquisition and a static projected pattern. The acquisition setup is less constrained than the ones proposed in the literature and requires only that the finger is placed according to the depth of focus of the cameras, and in the overlapping field of views. The obtained pairs of images are processed in order to extract the information related to the fingertip and the projected pattern. The projected pattern permits to extract a set of reference points in the two images, which are then matched by using a correlation approach. The information related to a previous calibration of the cameras is then used in order to estimate the finger model, and one input image is wrapped on the resulting three-dimensional model, obtaining a three-dimensional pattern with a limited distortion of the ridges. In order to obtain data that can be treated by traditional algorithms, the obtained three-dimensional models are then unwrapped into bidimensional images. The quality of the unwrapped images is evaluated by using a software designed for contact-based fingerprint images. The obtained results show that the methodology is feasible and a realistic three-dimensional reconstruction can be achieved with few constraints. These results also show that the fingertip models computed by using our approach can be processed by both specific three-dimensional matching algorithms and traditional matching approaches. We also compared the results with the ones obtained without using structured light techniques, showing that the use of a projector achieves a faster and more accurate fingertip reconstruction.
A composite and scalable cache coherence protocol for large scale CMPs

The number of on-chip cores of modern chip multiprocessors (CMPs) is growing fast with technology scaling. However, it remains a big challenge to efficiently support cache coherence for large scale CMPs. The conventional snoopy and directory coherence protocols cannot be smoothly scaled to many-core or thousand-core processors. Snoopy protocols introduce large power overhead due to enormous amount of cache tag probing triggered by broadcast. Directory protocols introduce performance penalty due to indirection, and large storage overhead due to storing directories. This paper addresses the efficiency problem when supporting cache coherency for large-scale CMPs. By leveraging emerging optical on-chip interconnect (OP-I) technology to provide high bandwidth density, low propagation delay and natural support for multicast/broadcast in a hierarchical network organization, we propose a composite cache coherence (C3) protocol that benefits from direct cache-to-cache accesses as in snoopy protocol and small amount of cache probing as in directory protocol. Targeting at quickly completing coherence transactions, C3 organizes accesses in a three-tier hierarchy by combining a mix of designs including local broadcast prediction, filtering, and a coarse-grained directory. Compared to directory-based protocol[18], our evaluations on a thousand-core CMP show that C3 improves performance by 21%, reduces network latency of coherence messages by 41% and saves network energy consumption by 5.5% on average for PARSEC applications.
Thoughts without a thinker, mimetic fusing and the anti-container considered as primitive defensive mechanisms in the addictions

This paper explores certain primitive defensive mechanisms found with addicted patients and introduces one of these, an intra-psychic mechanism, termed mimetic fusing. The descriptive concept of mimetic fusing is introduced in order to illuminate the processes by which a primitive self appears to repeat attempts to assimilate and detoxify introjections that are felt to be threatening and that generate intense anxiety. It is suggested that in the absence of an adequate container (Bion, 1962. A theory of thinking. International Journal of Psycho-Analysis, 43(4-5)), mimetic fusing may develop as a defensive mechanism to assimilate aggressively imbued introjections that threaten to overwhelm a fragile self-structure. The author suggests that mimetic fusing may represent a desperate defensive strategy that ultimately leads to the increased use of other basic defences such as splitting, the anti-container, anti-time and projective identification. Case material, taken from work with an addicted patient in longer term weekly psychotherapy, is included to illustrate the theoretical points under discussion.
Prosthetic rehabilitation, implant survival and quality of life 2 to 5 years after resection of oral tumors.

BACKGROUND After oral tumor resection, structural and functional rehabilitation by means of dental prostheses is complex, and positive treatment outcome is not always predictable. PURPOSE The objective of the study was to report on oral rehabilitation and quality of life 2-5 years after resection of malignant oral tumors. MATERIALS AND METHODS Data of 46 patients (57 ± 7 years) who underwent oral tumor surgery were available. More than 50% of tumors were classified T3 or T4. Open oro-nasal defects resulted in 12 patients and full mandibulary block resections in 23 patients. Comprehensive planning, implant placement, and prosthetic rehabilitation followed an interdisciplinary protocol. Analysis comprised tumor location, type of prostheses, implant survival, and quality of life. RESULTS Because of advanced tumor status, resections resulted in marked alteration of the oral anatomy requiring complex treatment procedures. Prosthetic rehabilitation comprised fixed and removable prostheses, with 104 implants placed in 28 patients (60%). Early implant loss was high (13%) and cumulative survival rate of loaded implants was <90% after 5 years. Prosthetic plans had to be modified because of side effects of tumor therapy, complications with implants and tumor recurrence. The majority of patients rated quality of life favorable, but some experienced impaired swallowing, dry mouth, limited mouth opening, appearance, and soreness. CONCLUSIONS Some local effects of tumor therapy could not be significantly improved by prosthetic rehabilitation leading to functional and emotional disability. Many patients had passed away or felt too ill to fill the questionnaires. This case series confirms the complex anatomic alterations after tumor resection and the need for individual treatment approaches especially regarding prosthesis design. In spite of disease-related local and general restrictions, most patients gave a positive assessment of quality of life.
Leukocyte mitochondrial DNA copy number, anthropometric indices, and weight change in US women

Objectives To examine the association between leukocyte mitochondrial DNA copy number (mtCN) and different anthropometric indices as well as weight changes; and to compare mtCN and telomere length with respect to their associations with BMI and age. Design Population based cohort study. Setting Nurses' Health Study, an ongoing prospective cohort study of 121,700 nurses enrolled in 1976; in 1989-1990 a subset of 32,826 women provided blood samples. Participants 1,700 disease-free US women from case-control studies nested within the Nurses' Health Study with mtCN and telomere length measured who also have anthropometric measurements. Main outcome measure Relative mtCN and telomere lengths in peripheral blood leukocytes measured by quantitative real time polymerase chain reaction and various anthropometric measurements data from initial questionnaire. Results Leukocyte mtCN was inversely associated with current weight (LS means Q1-Q4: 0.07, 0.04, 0.03, −0.17; P trend =0.002), waist size (LS means Q1-Q4: 0.06, 0.05, −0.04, −0.06; P trend = 0.04), BMI (LS means normal light, normal heavy, overweight, pre-obese, obese: 0.11, −0.01, −0.04, 0.04, −0.25; P trend<0.0001), and waist-hip ratio (WHR) (LS means Q1-Q4: 0.06, 0.08, −0.04, −0.06; P trend = 0.03). A one-unit decrease in mtCN z score was equivalent to approximately 3.5 pounds of weight gain for an adult of 5′10″. In addition, weight gain was bi-directionally and inversely associated with mtCN. Moreover, mtCN was strongly positively correlated with telomere length (LS means Q1-Q4: −0.02, 0.09, 0.11, 0.33; P trend <0.0001). MtCN was inversely associated with BMI even after adjusting for telomere length (P trend =0.003), while telomere length was not associated with BMI. On the other hand, telomere length was inversely associated with age after adjusting for mtCN (P trend =0.04), while mtCN was not associated with age. Conclusions Our results provide compelling evidence for a potential bi-directional temporal relationship between mitochondrial-mediated oxidative stress-defense mechanisms and weight change.
Long-term outcome of patients with spinal myxopapillary ependymoma: treatment results from the MD Anderson Cancer Center and institutions from the Rare Cancer Network.

BACKGROUND Spinal myxopapillary ependymomas (MPEs) are slowly growing ependymal gliomas with preferential manifestation in young adults. The aim of this study was to assess the outcome of patients with MPE treated with surgery, radiotherapy (RT), and/or chemotherapy. METHODS The medical records of 183 MPE patients (male: 59%) treated at the MD Anderson Cancer Center and 11 institutions from the Rare Cancer Network were retrospectively reviewed. Mean patient' age at diagnosis was 35.5 ± 15.8 years. Ninety-seven (53.0%) patients underwent surgery without RT, and 86 (47.0%) were treated with surgery and/or RT. Median RT dose was 50.4 Gy. Median follow-up was 83.9 months. RESULTS Fifteen (8.2%) patients died, 7 of unrelated cause. The estimated 10-year overall survival was 92.4% (95% CI: 87.7-97.1). Treatment failure was observed in 58 (31.7%) patients. Local failure, distant spinal relapse, and brain failure were observed in 49 (26.8%), 17 (9.3%), and 11 (6.0%) patients, respectively. The estimated 10-year progression-free survival was 61.2% (95% CI: 52.8-69.6). Age (<36 vs ≥36 y), treatment modality (surgery alone vs surgery and RT), and extent of surgery were prognostic factors for local control and progression-free survival on univariate and multivariate analysis. CONCLUSIONS In this series, treatment failure of MPE occurred in approximately one third of patients. The observed recurrence pattern of primary spinal MPE was mainly local, but a substantial number of patients failed nonlocally. Younger patients and those not treated initially with adjuvant RT or not undergoing gross total resection were significantly more likely to present with tumor recurrence/progression.
Revisiting the Stop-and-Stare Algorithms for Influence Maximization

Influence maximization is a combinatorial optimization problem that finds important applications in viral marketing, feed recommendation, etc. Recent research has led to a number of scalable approximation algorithms for influence maximization, such as TIM+ and IMM, and more recently, SSA and D-SSA. The goal of this paper is to conduct a rigorous theoretical and experimental analysis of SSA and D-SSA and compare them against the preceding algorithms. In doing so, we uncover inaccuracies in previously reported technical results on the accuracy and efficiency of SSA and D-SSA, which we set right. We also attempt to reproduce the original experiments on SSA and D-SSA, based on which we provide interesting empirical insights. Our evaluation confirms some results reported from the original experiments, but it also reveals anomalies in some other results and sheds light on the behavior of SSA and D-SSA in some important settings not considered previously. We also report on the performance of SSA-Fix, our modification to SSA in order to restore the approximation guarantee that was claimed for but not enjoyed by SSA. Overall, our study suggests that there exist opportunities for further scaling up influence maximization with approximation guarantees.
Leadership and Perceiver Cognition: Examining the Role of Self-Identity in Implicit Leadership Theories

We investigated whether priming individuals' self-identities to be interdependent or independent influences their ratings of leadership prototypicality. Specifically, we predicted that participants receiving an interdependent prime would rate items associated with transformational leadership as being more prototypical of effective leadership than would participants receiving no prime. We also predicted that participants receiving an independent prime would rate transactional leadership items as being more prototypical of effective leadership. Undergraduate psychology students were randomly assigned to one of three conditions (interdependent prime, independent prime, and control). Results support the idea that self-identity can be primed to influence ratings of leadership prototypicality. We discuss implications and suggest directions for future research.
The complex light curve of the afterglow of GRB 071010A

We present and discuss the results of an extensive observational campaign devoted to GRB071010A, a long-duration gamma-ray burst detected by the Swift satellite. This event was followed for almost a month in the optical/near-infrared (NIR) with various telescopes starting from about 2min after the high-energy event. Swift-XRT observations started only later at about 0.4d. The light-curve evolution allows us to single out an initial rising phase with a maximum at about 7min, possibly the afterglow onset in the context of the standard fireball model, which is then followed by a smooth decay interrupted by a sharp rebrightening at about 0.6d. The rebrightening was visible in both the optical/NIR and X-rays and can be interpreted as an episode of discrete energy injection, although various alternatives are possible. A steepening of the afterglow light curve is recorded at about 1d. The entire evolution of the optical/NIR afterglow is consistent with being achromatic. This could be one of the few identified GRB afterglows with an achromatic break in the X-ray through the optical/NIR bands. Polarimetry was also obtained at about 1d, just after the rebrightening and almost coincident with the steepening. This provided a fairly tight upper limit of 0.9% for the polarized-flux fraction.