Miracle-dz/UniFAR-FTUs huggingface dataset:
Study the Storage Temperature & Periods on Rheological Properties of Wheat Flour

When increasing the storage temperature from 27.5°C to 37.5°C the water absorption ratio of the flour is significantly increased. Besides, the average ratio of absorption of flour has increased more significantly when increasing storage period from one day to ten days, and by increasing the period of storage from ten days to thirty days, the increase is also significant. The overlap of the two factors of this study has a significant effect on this manner. There has been a significant increase in the time development of the dough at a storage temperature of 37.5°C, compared to 27.5°C. of storage. But, however, there has not been a significant effect of the storage periods or their overlapping with the temperature storage on this manner. It has been observed that the indicator of dough stability is higher when storing the flour under the temperature of 37.5°C in 4.45 minutes, compared with the stability of 2.23 minutes when storing the flour at a temperature of 27.5°C. On the other hand, increasing the period of storage from one day to ten days has led to a significant decrease in the stability of the dough, but in increasing the period to twenty days to thirty days, the high capacity of these would not reach the level of significance. The overlap, however, between these two factors has a significant effect on the stability of the dough.
Infection of Immunodeficient Horses with Sarcocystis neurona Does Not Result in Neurologic Disease

ABSTRACT Equine protozoal myeloencephalitis is a progressive neurologic disease of horses most commonly caused by infection with the apicomplexan parasite Sarcocystis neurona. Factors affecting neuroinvasion and neurovirulence have not been determined. We investigated the pathogenesis of infection with S. neurona in horses with severe combined immune deficiency (SCID). Two immunocompetent (IC) Arabian horses and two Arabian horses with SCID were infected orally with 5 × 105 sporocysts of S. neurona. Four IC horses and one SCID horse were infected intravenously (i.v.) with 5 × 108 merozoites of the WSU-1 isolate of S. neurona. Despite prolonged parasitemia and persistent infection of visceral tissues (skeletal muscle, cardiac muscle, lung, liver, and spleen) as demonstrated by PCR and culture, SCID horses did not develop neurologic signs after oral or i.v. infection. S. neurona was undetectable in the neuronal tissues of SCID horses by either PCR, immunohistochemistry, or culture. In contrast, although parasitemia was undetectable in orally infected IC horses and of only short duration in i.v. infected IC horses, four of six IC horses developed neurologic signs. S. neurona was detectable by PCR and/or culture of neural tissue but not visceral tissue of IC horses with neurologic disease. Infected SCID horses are unable to clear S. neurona from visceral tissues, but the infection does not result in neurologic signs; in contrast, IC horses rapidly control parasitemia and infection of visceral tissues but frequently experience neuroinvasion and exhibit clinical signs of neurologic disease.
Tailoring Structural and Energy-related Properties of Thin Films Using HiPIMS

High power impulse magnetron sputtering (HiPIMS) is a thin film deposition technique where the deposition flux is predominantly composed of ionized sputtered material. This enables control of energy and direction of the film-forming species and is thereby beneficial for tailoring the film structure and final properties. Although researchers world-wide have spent significant time and efforts characterizing and understanding the plasma process conditions in HiPIMS, research in new and improved HiPIMS-based thin film materials that find applications in areas of importance for society is still required. The goal of this work has been to identify and optimize the deposition parameters that allow tailoring the film microstructure, intrinsic stress and energy-related properties, such as electrical resistivity and optical band gap, to ultimately achieve superior HiPIMS coatings compared to what is achieved today using conventional deposition techniques. Three material systems constitute the core of the work: copper, titanium dioxide, and titanium nitride. From the work carried out it is concluded that the most important parameters affecting the film structure and properties are the amount as well as the kinetic energy of the ionized sputtered species irradiating the film during growth. These parameters differ substantially for optimum growth conditions of metallic and compound films.
Poe or not Poe? A stylometric analysis of Edgar Allan Poe's disputed writings

Edgar Allan Poe has left us with a literary legacy that in part lacks a definitive stamp of authenticity. While some of the ‘possible Poes’ that have been discovered after his death have generated heated discussion among scholars, many others have quickly slipped into obscurity. This paper reevaluates thirty-two of such prose texts as well as ten poems that have been tenuously attributed to Poe in the past, using the ‘classify’ function (employing Nearest Shrunken Centroid, Burrows’ Delta and Support Vector Machines) of the stylo-toolkit for R . It also sheds new light (with the help of rolling Delta) on Poe’s possible contribution to the so-called Paulding-Drayton review, infamous in Poe criticism for its defense of slavery. By contrasting and comparing the ‘author signal’ behind these pieces with unclear authorship, this analysis is able to answer with a high degree of accuracy the question: Poe or not Poe?
Photodynamics of photo-activated BLUF coupled Endonuclease III mutant RmPAE from mesophilic, pigmented bacterium Rubellimicrobium mesophilum strain MSL-20T

The pink to light reddish-pigmented bacterium Rubellimicrobium mesophilum strain MSL-20T contains a BLUF coupled endonuclease III of unknown function. A purified recombinant triple mutated sample of the BLUF coupled endonuclease III (F5Y, N27H, A87W) named RmPAE (Rubellimicrobium mesophilum Photo-Activated Endonuclease) was produced and characterized by optical spectroscopic methods. The BLUF domain photo-cycling dynamics occurred with high efficient blue-light induced signaling state formation (quantum yield of signaling state formation φs ≈ 0.6), small spectral red-shift (δλs,r ≈ 5.4 nm), and slow thermal activated dark recovery to the receptor state (τrec ≈ 20 min at room temperature). An apparent RmPAE melting temperature of ϑm ≈ 63 °C was determined by stepwise sample heating and absorption spectrum analysis. The photo-degradation of RmPAE in the signaling state was determined by prolonged intense blue-light exposure. An irreversible flavin photo-degradation occurred with quantum yield of φD ≈ 2.6×10-5. Schemes of the photo-cycling and the photo-degradation dynamics are presented. Engineered RmPAE may find application as light guided DNA cutter in optogenetic applications.
In-memory adder functionality in 1S1R arrays

Memristive devices enable non-volatile data storage and in-memory computing capabilities. By using stateful logic approaches, hybrid CMOS nano-crossbar arrays offer additional functionalities such as arithmetic operations. To enable storage and computing on large-scale arrays, parasitic current paths within the array must be avoided. Therefore, for example, a complementary resistive switch (1CRS) or a bipolar rectifying element (`selector') in series to a resistive switching device (1S1R) is required at each cross-point junction to suppress low-ohmic sneak paths. In this work 1S1R arrays are considered. First, the in-memory adder concept, initially developed for CRS arrays, is adjusted for a 1S1R array. After that an optimized design is presented and verified by means of memristive simulations. Third, the energy consumption of both concepts is evaluated as a function of array size, and the delay of memristive adder designs are compared quantitatively.
Trajectory planning of robot manipulators by using algebraic and trigonometric splines

In this paper, the use of algebraic and trigonometric splines for the trajectory planning of robot manipulators is discussed. First, the two methods are analyzed and compared in detail; then, a strategy, which involves a combined use of the two schemes to perform sudden changes in a predefined trajectory (e.g. in case of obstacle avoidance) is proposed. Results show that the main interest in using trigonometric splines lies especially in the task of connecting two separate pieces of cubic splines, as overshoots are significantly reduced, although the continuity of velocity, acceleration and (in case) jerk is guaranteed.
Sparse Overlap Cross-Platform Recommendation Via Adaptive Similarity Structure Regularization

People often use multiple platforms to fulfill their different information needs, which has opened opportunities for research on the cross-platform recommendation. Existing cross-platform recommendation works either assume no overlapping users on different platforms or require enough overlapping users to reach a good performance. None of them pays attention to the sparse overlap problem, that is, the number of observed overlapping users of different platforms is very small. In this paper, we propose a cross-platform recommendation framework termed Adaptive Similarity Structure Regularization Through Connector (AdaSTC), which adaptively learns the user similarity structure on different platforms and further uses it to regularize the modeling process of user preference. Experiments conducted on two real-world datasets demonstrate that AdaSTC significantly outperforms the state-of-the-art methods in the sparse overlap situation.
Use of 16S rRNA Sequencing for Identification of Actinobacillus ureae Isolated from a Cerebrospinal Fluid Sample

ABSTRACT Actinobacillus ureae, previously Pasteurella ureae, has on rare occasions been described as a cause of human infection. Owing to its rarity, it may not be easily identified in clinical microbiology laboratories by standard tests. This report describes a patient with acute bacterial meningitis due to A. ureae. The identity of the isolate was determined by means of DNA sequence analysis of a portion of the 16S rRNA gene.
Tagging tagging. Analysing user keywords in scientific bibliography management systems

In this paper, an empirical study of tagging behaviour in web-based bibliographic annotation systems is presented. Starting from an initial category finding phase in which tags attributed to selected articles from Connotea were classified we have set up a category model for linguistic and functional aspects of tag usage as well as for the relationship between tags and document full text. In a second phase this model is applied to approx. 500 tagged articles from the information and computer technology domain randomly selected from Connotea. Our findings show significant differences to other tagging research which was primarily conducted using popular (non-scientific) tagging platforms like Flickr or Delicious. We observe a great overlap of tag material and document text and rather few non-content related tags. The comparison of user tags with author keywords shows that users tend to use less and more general tags. Finally, system functionality seems to play a role for users’ tagging behaviour.
Libratus: The Superhuman AI for No-Limit Poker

No-limit Texas Hold'em is the most popular variant of poker in the world. Heads-up no-limit Texas Hold'em is the main benchmark challenge for AI in imperfect-information games. We present Libratus, the first--and so far only--AI to defeat top human professionals in that game. Libratus's architecture features three main modules, each of which has new algorithms: pre-computing a solution to an abstraction of the game which provides a high-level blueprint for the strategy of the AI, a new nested subgame-solving algorithm which repeatedly calculates a more detailed strategy as play progresses, and a self-improving module which augments the pre-computed blueprint over time.
OPTIMASI PROSES PEMBUATAN BIOPLASTIK DARI PATI LIMBAH KULIT SINGKONG

Penelitian ini bertujuan mendapatkan kondisi proses optimum pengolahan plastik biodegradabel dari pati kulit singkong dengan bahan tambahan kitosan dan plasticizer gliserol. Hasil yang diperoleh berupa lembaran plastik tipis (film plastik) yang telah diuji biodegradabelitas, ketahanan air dan FT-IR. Hasil kondisi optimum yang diperoleh menunjukkan suhu optimum pengeringan berada pada 61,03◦C dan waktu pengeringan 117 menit dengan perolehan biodegradabilitas 72,05 %, penyerapan air 25,68 %. Hasil uji FT-IR menunjukkan bahwa plastik biodegradabel yang dihasilkan memiliki gugus fungsi CH, OH dan NH.
CAN NEUROSCIENCE ADVANCE SOCIAL PSYCHOLOGICAL THEORY? SOCIAL NEUROSCIENCE FOR THE BEHAVIORAL SOCIAL PSYCHOLOGIST

Social neuroscience is a young and thriving area of research in psychology that integrates diverse literatures and methodologies to address broad questions about the brain and behavior. But despite the excitement and activity generated by this approach, its contribution to ideas in social psychology is sometimes questioned. This article discusses the ways in which social neuroscience research may or may not contribute to theoretical issues in social psychology. Still a young field, much research in this area has focused on issues of brain mapping and methodological development, with less emphasis on generating and testing novel social psychological hypotheses. The challenges to theoretical advancement, including psychometric and methodological issues, are considered, and a set of guidelines for conducting theoretically-informative social neuroscience is offered. In the final analysis, it is argued that neuroscience has much to offer to social psychology, both theoretically and methodologically, but that l.
The Road to Pell is Paved with Good Intentions: The Economic Incidence of Federal Student Grant Aid

The federal Pell Grant Program provides billions of dollars in subsidies to low-income college students to increase affordability and access to higher education. I estimate the economic incidence of these subsidies using regression discontinuity (RD) and regression kink (RK) designs. RK estimates suggest that schools capture Pell Grant aid through price discrimination, while RD estimates imply the opposite result, that schools supplement Pell Grants with increased institutional aid. I reconcile these disparate findings through a framework in which the treatment of Pell Grant aid is multidimensional: students receive an additional dollar of Pell Grant aid and are also labeled as Pell Grant recipients. RD estimates confound the effects of these dimensions, which have opposite impacts on schools’ pricing decisions. I develop a combined RD/RK approach, which allows me to separately identify schools’ willingness to pay for students categorized as needy and the pricing response to outside subsidies. Taking into account both dimensions, I estimate that 12 percent of all Pell Grant aid is passed-through to schools. JEL: H22, I21,
Engineering Pseudomonas fluorescens for Biodegradation of 2,4-Dinitrotoluene

ABSTRACT Using the genes encoding the 2,4-dinitrotoluene degradation pathway enzymes, the nonpathogenic psychrotolerant rhizobacterium Pseudomonas fluorescens ATCC 17400 was genetically modified for degradation of this priority pollutant. First, a recombinant strain designated MP was constructed by conjugative transfer from Burkholderia sp. strain DNT of the pJS1 megaplasmid, which contains the dnt genes for 2,4-dinitrotoluene degradation. This strain was able to grow on 2,4-dinitrotoluene as the sole source of carbon, nitrogen, and energy at levels equivalent to those of Burkholderia sp. strain DNT. Nevertheless, loss of the 2,4-dinitrotoluene degradative phenotype was observed for strains carrying pJS1. The introduction of dnt genes into the P.fluorescens ATCC 17400 chromosome, using a suicide chromosomal integration Tn5-based delivery plasmid system, generated a degrading strain that was stable for a long time, which was designated RE. This strain was able to use 2,4-dinitrotoluene as a sole nitrogen source and to completely degrade this compound as a cosubstrate. Furthermore, P. fluorescens RE, but not Burkholderia sp. strain DNT, was capable of degrading 2,4-dinitrotoluene at temperatures as low as 10°C. Finally, the presence of P. fluorescens RE in soils containing levels of 2,4-dinitrotoluene lethal to plants significantly decreased the toxic effects of this nitro compound on Arabidopsis thaliana growth. Using synthetic medium culture, P. fluorescens RE was found to be nontoxic for A.thaliana and Nicotiana tabacum, whereas under these conditions Burkholderia sp. strain DNT inhibited A.thaliana seed germination and was lethal to plants. These features reinforce the advantageous environmental robustness of P. fluorescens RE compared with Burkholderia sp. strain DNT.
Factors influencing inclusion body formation in the production of a fused protein in Escherichia coli

Different parameters that influenced the formation of inclusion bodies in Escherichia coli during production of a fused protein consisting of protein A from Staphylococcus aureus and beta-galactosidase from E. coli were examined. The intracellular expression of the fused protein was controlled by the pR promoter and its temperature-sensitive repressor. The induction temperature, the pH of the cultivation medium, and changes in the amino acid sequence in the linker region between protein A and beta-galactosidase had a profound effect on the formation of inclusion bodies. At 42 degrees C, inclusion bodies were formed only during the first hours after induction, and thereafter all the recombinant protein that was further produced appeared in a soluble and active state. Production at 39 and 44 degrees C resulted in inclusion body formation throughout the production period with 15 to 20% of the produced recombinant protein appearing as inclusion bodies. Cultivating cells without control of pH caused inclusion body formation throughout the induction period, and inclusion body formation increased with decreasing pH, and at least part of the insoluble protein was formed from the pool of soluble fusion protein within the cell. Changes in the amino acid sequence in the linker region between the two parts of the fusion protein abolished inclusion body formation.
Improved Battery Parameter Estimation Method Considering Operating Scenarios for HEV/EV Applications

This paper presents an improved battery parameter estimation method based on typical operating scenarios in hybrid electric vehicles and pure electric vehicles. Compared with the conventional estimation methods, the proposed method takes both the constant-current charging and the dynamic driving scenarios into account, and two separate sets of model parameters are estimated through different parts of the pulse-rest test. The model parameters for the constant-charging scenario are estimated from the data in the pulse-charging periods, while the model parameters for the dynamic driving scenario are estimated from the data in the rest periods, and the length of the fitted dataset is determined by the spectrum analysis of the load current. In addition, the unsaturated phenomenon caused by the long-term resistor-capacitor (RC) network is analyzed, and the initial voltage expressions of the RC networks in the fitting functions are improved to ensure a higher model fidelity. Simulation and experiment results validated the feasibility of the developed estimation method.
Effect of methomyl on hepatic mixed function oxidases in rats

Objective: To study the effect of the methomyl on mixed function oxidase system in rats. Materials and Methods: The effect of the methomyl on mixed function oxidase was studied using different dosages, durations and sex. Microsomes were isolated using the calcium precipitation method. The levels of cytochrome P450 , and cytochrome b5 were determined using extinction coefficient of 91 and 85 mM-1 respectively. The activities of drug metabolizing enzymes, hemoglobin content, liver function enzymes, and serum cholinesterase activity were assayed by using standard methods. Results: Intraperitoneal administration of methomyl (4 mg/kg body weight) showed significant decrease in the level of cytochrome P450 , and the activities of aminopyrine N-demethylase and aniline hydroxylase on the third day of the treatment. Methomyl (4 mg/kg) treatment of old male rat and adult female rat also showed a decrease in the level of cytochrome P450 , and aminopyrine N-demethylase activity. The serum samples from methomyl treated rats (male and female), when analyzed for alanine aminotransferase (SGPT) and aspartate aminotransferase (SGOT) as markers of the liver toxicity, showed significant increase in the activity. The activities of SGPT and SGOT were significantly higher in the treated rats (2 and 4 mg/kg) than in the control group. A significant decrease in the level of hemoglobin and serum cholinesterase activity was observed, when there was an increase in the dose level. A significant increase was observed in alkaline phosphatase activity at all dose levels. Conclusion: Methomyl influences mixed function oxidase and creates abnormality of liver functions in the rats. This effect depends on the dose and duration of methomyl.
Role of miR-21 and its signaling pathways in renal diseases

Abstract miRNAs are endogenous non-coding RNAs that are ∼22 nucleotides in length and can have structural, enzymatic and regulatory functions. miRNAs play important roles in the progression of renal fibrosis. miR-21, through a feed-forward loop and a downstream mediator of transforming growth factor-β (TGF-β), amplifies TGF-β signaling and promotes fibrosis. miR-21 is high on the list of non-coding, small, regulatory RNAs that promote renal fibrosis and emerges as a serum biomarker for kidney diseases, but many questions await answers. This review was performed to sum up the role of miR-21 and its signaling pathways in renal diseases.
Regulation of IFN Regulatory Factor 4 Expression in Human T Cell Leukemia Virus-I-Transformed T Cells1

IFN regulatory factor (IRF)-4 is a lymphoid/myeloid-restricted member of the IRF transcription factor family that plays an essential role in the homeostasis and function of mature lymphocytes. IRF-4 expression is tightly regulated in resting primary T cells and is transiently induced at the mRNA and protein levels after activation by Ag-mimetic stimuli such as TCR cross-linking or treatment with phorbol ester and calcium ionophore (PMA/ionomycin). However, IRF-4 is constitutively upregulated in human T cell leukemia virus type I (HTLV-I) infected T cells as a direct gene target for the HTLV-I Tax oncoprotein. In this study we demonstrate that chronic IRF-4 expression in HTLV-I-infected T lymphocytes is associated with a leukemic phenotype, and we examine the mechanisms by which continuous production of IRF-4 is achieved in HTLV-I-transformed T cells. IRF-4 expression in HTLV-1-infected cells is driven through activation of the NF-κB and NF-AT pathways, resulting in the binding of p50, p65, and c-Rel to the κB1 element and p50, c-Rel, and NF-ATp to the CD28RE element within the −617 to −209 region of the IRF-4 promoter. Furthermore, mutation of either the κB1 or CD28RE sites blocks Tax-mediated transactivation of the human IRF-4 promoter in T cells. These experiments constitute the first detailed analysis of human IRF-4 transcriptional regulation within the context of HTLV-I infection and transformation of CD4+ T lymphocytes.