Miracle-dz/UniFAR-FTUs huggingface dataset:
Three Dimensions of Dissociative Amnesia

Principal axis factor analysis with promax rotation extracted 3 factors from the 42 memory and amnesia items of the Multidimensional Inventory of Dissociation (MID) database (N = 2,569): Discovering Dissociated Actions, Lapses of Recent Memory and Skills, and Gaps in Remote Memory. The 3 factors' shared variance ranged from 36% to 64%. Construed as scales, the 3 factor scales had Cronbach's alpha coefficients of . 96, . 94, and . 93, respectively. The scales correlated strongly with mean Dissociative Experiences Scale scores, mean MID scores, and total scores on the Structured Clinical Interview for DSM–IV Dissociative Disorders–Revised (SCID-D-R). What is interesting is that the 3 amnesia factors exhibited a range of correlations with SCID-D-R Amnesia scores (.52, .63, and .70, respectively), suggesting that the SCID-D-R Amnesia score emphasizes gaps in remote memory over amnesias related to dissociative identity disorder. The 3 amnesia factor scales exhibited a clinically meaningful pattern of significant differences among dissociative identity disorder, dissociative disorder not otherwise specified–1, dissociative amnesia, depersonalization disorder, and nonclinical participants. The 3 amnesia factors may have greater clinical utility for frontline clinicians than (a) amnesia as discussed in the context of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, nosology of the dissociative disorders or (b) P. Janet's (1893/1977) 4-fold classification of dissociative amnesia. The author recommends systematic study of the phenomenological differences within specific dissociative symptoms and their differential relationship to specific dissociative disorders.
The aluminoarsenate K1.8Sr0.6Al3(AsO4)4

The title compound, potassium strontium trialuminium tetraarsenate, was prepared by solid-state reaction. The structure consists of AlO6 octahedra (site symmetries 2. and 2/m) and two AsO4 tetrahedra (.2. and m.) sharing corners and edges to form a two-dimensional structure parallel to (010). The cations are occupationally disordered and are located in the interlayer space. For both types of cations, distorted coordination polyhedra are observed.
Clinical factors for the development of posttraumatic hydrocephalus after decompressive craniectomy.

OBJECTIVE Earlier reports have revealed that the incidence of posttraumatic hydrocephalus (PTH) is higher among patients who underwent decompressive craniectomy (DC). The aim of this study was to determine the influencing factors for the development of PTH after DC. METHODS A total of 693 head trauma patients admitted in our hospital between March 2004 and May 2007 were reviewed. Among thee, we analyzed 55 patients with severe traumatic brain injury who underwent DC. We excluded patients who had confounding variables. The 33 patients were finally enrolled in the study and data were collected retrospectively for these patients. The patients were divided into two groups: non-hydrocephalus group (Group I) and hydrocephalus group (Group II). Related factors assessed were individual Glasgow Coma Score (GCS), age, sex, radiological findings, type of operation, re-operation and outcome. RESULTS Of the 693 patients with head trauma, 28 (4.0%) developed PTH. Fifty-five patients underwent DC and 13 (23.6%) developed PTH. Eleven of the 33 study patients (30.3%) who had no confounding factors were diagnosed with PTH. Significant differences in the type of craniectomy and re-operation were found between Group I and II. CONCLUSION It is suggested that the size of DC and repeated operation may promote posttraumatic hydrocephalus in severe head trauma patients who underwent DC.
Effect of water intake on the progression of chronic renal failure in the 5/6 nephrectomized rat.

This study tests the possible influence of the urinary concentrating process and/or of vasopressin (AVP) on the progression of early chronic renal failure (CRF). Male Sprague-Dawley rats were submitted to 5/6 nephrectomy and were offered water ad libitum throughout the study. In addition, half of the rats (high water intake, HWI) received their food mixed with a water-rich agar gel. The other rats (normal water intake, NWI) ate the same amount of food plus agar in the usual dry powder form. This resulted in doubling the daily water ingestion in HWI. Renal function was studied for 10 wk and kidney morphology assessed thereafter. Increased water intake in HWI reduced solute-free water reabsorption and urine osmolality about threefold to 12 +/- 1 ml/day and 390 +/- 9 mosmol/kgH2O, respectively (week 5 as example). Hematocrit, plasma sodium, and plasma creatinine concentration were unchanged. The progressive increases in urinary protein excretion and in systolic blood pressure observed in this model of CRF were significantly slowed in HWI compared with NWI (at week 5, 8.6 +/- 1.8 vs. 23.1 +/- 6.2 mg protein/day and 142 +/- 8 vs. 167 +/- 10 mmHg, respectively). Remnant kidney weight per unit body weight was 21% lower in HWI than in NWI (P less than 0.02). Incidence of glomerulosclerosis was also reduced and was correlated with kidney weight (P less than 0.01). AVP plasma level (PAVP) and plasma renin activity (PRA) were measured in additional rats. PAVP was about twofold higher (P less than 0.05) and PRA twofold lower (P less than 0.001) in rats with 5/6 nephrectomy than in control rats with two kidneys. (ABSTRACT TRUNCATED AT 250 WORDS)
The analytical study of Altman Z score on NIFTY 50 Companies

Stock market investments are subject to market risks and there is a possibility for loosing of all the money invested. Investment decisions are so crucial for a successful investor. Investors are using different techniques for stock selection and for investment. The Altman Z-score is a widely used measure that applies an algorithm that has been found to have useful predictive value on the likelihood of a business going bankrupt. In this paper trying to assess the Altman Z-score of NIFTY 50 companies excluding banks and financial companies. The score tries to predict probability of default by the companies due to the financial distress based on the current financial statistics of the company.
Psychotic experiences and PTSD: exploring associations in a population survey

Background Extensive evidence has shown that experiencing a traumatic event and post-traumatic stress disorder (PTSD) are associated with experiences of psychosis. However, less is known about specific PTSD symptoms and their relationship with psychotic experiences. This study aimed to examine the relationship between symptoms of PTSD with paranoia and auditory hallucinations in a large-scale sample. Method The Adult Psychiatric Morbidity Survey (APMS) was utilized to examine the prevalence of lifetime trauma, symptoms of PTSD, and experiences of paranoia and auditory hallucinations (n = 7403). Results There were significant bivariate associations between symptoms of PTSD and psychotic experiences. Multiple logistic regression analyses indicated that reliving and arousal symptoms were significant predictors for paranoia while reliving, but not arousal symptoms, also significantly predicted auditory hallucinations. A dose-response relationship was found, the greater the number of PTSD symptoms, the greater the odds were of experiencing both paranoia and hallucinations. Conclusions These findings illustrate that symptoms of PTSD are associated with increased odds of experiencing auditory hallucinations and paranoia. Overlaps appear to be present between the symptoms of PTSD and psychotic experiences. Increasing awareness of this association may advance work in clinical practice.
The Drosophila melanogaster pheromone Z4-11Al is encoded together with habitat olfactory cues and mediates species-specific communication

Mate recognition in animals evolves during niche adaptation and involves habitat and social olfactory signals. Drosophila melanogaster is attracted to fermenting fruit for feeding and egg-laying. We show that, in addition, female flies release a pheromone (Z)-4-undecenal (Z4-11Al), that elicits flight attraction in both sexes. The biosynthetic precursor of Z4-11Al is the cuticular hydrocarbon (Z,Z)-7,11-heptacosadiene (7,11-HD), which is known to afford reproductive isolation between the sibling species D. melanogaster and D. simulans. A pair of alternatively spliced receptors, Or69aB and Or69aA, is tuned to Z4-11Al and to food olfactory cues, respectively. These receptors are co-expressed in the same olfactory sensory neurons, and feed into a neural circuit mediating species-specific, long-range communication: the close relative D. simulans, which shares food resources and co-occurs with D. melanogaster, does not respond. That Or69aA and Or69aB have adopted dual olfactory traits highlights the interplay of habitat and social signals in mate finding. These olfactory receptor genes afford a collaboration between natural and sexual selection, which has the potential to drive phylogenetic divergence. Significance Statement Volatile insect sex pheromones carry a message over a distance, they are perceived by dedicated olfactory receptors, and elicit a sequence of innate behaviours. Pheromones mediate specific mate recognition, but are embedded in and perceived together with environmental olfactory cues. We have identified the first long-range, species-specific pheromone in Drosophila melanogaster. A pair of spliced olfactory receptors, feeding into the same neural circuit, has developed a dual affinity to this pheromone and kairomones, encoding adult and larval food. Blends of this pheromone and kairomone specifically attract D. melanogaster, but not the close relative D. simulans. This becomes an excellent paradigm to study the interaction of social signals and habitat olfactory cues in premating reproductive isolation and phylogenetic divergence.
Racial Differences in Surgeons and Hospitals for Endometrial Cancer Treatment

Purpose:To determine whether (1) black and white women with endometrial cancer were treated by different surgical specialties and in different types of hospitals and (2) differences in specialty and hospital type contributed to racial differences in survival. Methods:Retrospective cohort study of 12,307 women aged 65 years and older who underwent surgical treatment of endometrial cancer between 1991 and 1999 in the 11 Surveillance Epidemiology and End Results registries. Results:Black women were more likely to have a gynecologic oncologist to perform their surgery and to be treated at hospitals that were higher volume, larger, teaching, National Cancer Institute centers, urban, and where a greater proportion of the surgeries were performed by a gynecologic oncologist. In unadjusted models, black women were over twice as likely as white women who died because of cancer (hazards ratio [HR]: 2.33), but nearly all of the initial racial difference in survival was explained by differences in cancer stage, and grade as well as age and comorbidities at presentation (adjusted HR: 1.10). Surgical specialty was not associated with survival and, of the hospital characteristics studied, only surgical volume was associated with survival (P < 0.005). Adjusting for hospital characteristics did not change the racial difference in survival (HR: 1.10). Adjustment for the specific hospital where the woman was treated eliminated the association between race and surgeon specialty and slightly widened the residual racial difference in survival (HR: 1.23 vs. 1.10). Conclusions:In contrast to several studies suggesting that blacks with breast cancer, colon cancer, or cardiovascular disease are treated in hospitals with lower quality indicators, black women diagnosed with endometrial cancer in Surveillance Epidemiology and End Results regions between 1991 and 1999 were more likely to be treated by physicians with advanced training and in high volume, large, urban, teaching hospitals. However, except for a modest association with hospital surgical volume, these provider and hospital characteristics were largely unrelated to survival for women with endometrial cancer. The great majority of the difference in survival was explained by differences in tumor and clinical characteristics at presentation.
A link prediction approach for drug recommendation in disease-drug bipartite network

Social networks we have encountered in different areas and in different forms have a dynamic structure because the relationships they define constantly change. Link prediction is an important and effective solution to understand this dynamic nature of networks and to identify future relations. It estimates of possible future connections between nodes in the network taking advantage of network's current state. In this study, a method for link prediction in the disease-drug network is proposed. Sofar, the most of studies done is usually based on connection prediction in single mode networks. This method has been applied on a bipartite such as disease-drug network, as apart from single mode networks. To compare performance of the proposed method, four of similarity based link prediction methods has been also applied to the network. The results obtained from experiments show that the proposed method has a good percentage of success than the other similarity based link prediction methods.
Oxidised LDL internalisation by the LOX-1 scavenger receptor is dependent on a novel cytoplasmic motif and is regulated by dynamin-2

The LOX-1 scavenger receptor recognises pro-atherogenic oxidised low-density lipoprotein (OxLDL) particles and is implicated in atherosclerotic plaque formation, but this mechanism is not well understood. Here we show evidence for a novel clathrin-independent and cytosolic-signal-dependent pathway that regulates LOX-1-mediated OxLDL internalisation. Cell surface labelling in the absence or presence of OxLDL ligand showed that LOX-1 is constitutively internalised from the plasma membrane and its half-life is not altered upon ligand binding and trafficking. We show that LOX-1-mediated OxLDL uptake is disrupted by overexpression of dominant-negative dynamin-2 but unaffected by CHC17 or μ2 (AP2) depletion. Site-directed mutagenesis revealed a conserved and novel cytoplasmic tripeptide motif (DDL) that regulates LOX-1-mediated endocytosis of OxLDL. Taken together, these findings indicate that LOX-1 is internalised by a clathrin-independent and dynamin-2-dependent pathway and is thus likely to mediate OxLDL trafficking in vascular tissues.
The Carboxyl Terminus of Zona Occludens-3 Binds and Recruits a Mammalian Homologue of Discs Lost to Tight Junctions*

Mammalian homologues of theDrosophila polarity proteins Stardust, Discs Lost, and Crumbs have been identified as Pals1,Pals1-associated tightjunction protein (PATJ), and human Crumbs homologue 1 (CRB1), respectively. We have previously demonstrated that PATJ, Pals1, and CRB1 can form a tripartite tight junction complex in epithelial cells and that PATJ recruits Pals1 to tight junctions. Here, we observed that the Pals1/PATJ interaction was not crucial for the ultimate targeting of PATJ itself to tight junctions. This prompted us to examine if any of the 10 post-synaptic density-95/Discs Large/zona occludens-1 (PDZ) domains of PATJ could bind to the carboxyl termini of known tight junction constituents. We found that the 6thand 8th PDZ domains of PATJ can interact with the carboxyl termini of zona occludens-3 (ZO-3) and claudin 1, respectively. PATJ missing the 6th PDZ domain was found to mislocalize away from cell contacts. Surprisingly, deleting the 8th PDZ domain had little effect on PATJ localization. Finally, reciprocal co-immunoprecipitation experiments revealed that full-length ZO-3 can associate with PATJ. Hence, the PATJ/ZO-3 interaction is likely important for recruiting PATJ and its associated proteins to tight junctions.
Variation in university research ethics review: Reflections following an inter-university study in England

Conducting large multi-site research within universities highlights inconsistencies between universities in approaches, requirements and responses of research ethics committees. Within the context of a social science research study, we attempted to obtain ethical approval from 101 universities across England to recruit students for a short online survey. We received varied responses from research ethics committees of different universities with the steps to obtaining ethics approval ranging from those that only required proof of approval from our home institution, to universities that facilitated fast-track applications to those that required a full ethics review. Some universities also completely refused. After contacting all 101 universities in England, 60 universities gave clearance to our study. In this article, we present the different approaches universities adopted in response to our application to sample from students in their institution. We consider a number of conceptual and ethical issues pertinent to considering ethics approval for researchers from other universities in England and critically discuss three possible models of ethics governance that would cover all universities in England.
An extensible and real-time compressive sensing reconstruction hardware for WBANs using OMP

Compressive sensing theory, which allows sparse signal to be sampled at sub-Nyquist rate, is introduced to Wireless Body Area Networks to reduce the hardware requirement and energy consumption of signal acquisition. However, signal recovery by software causes time delay for real-time reconstruction. In this paper, we propose a high speed hardware implementation of orthogonal matching pursuit reconstruction algorithm in SMIC 130nm CMOS. By using original multi-functional systolic arrays, it is highly parallel and extensible. Experimental result shows that it completes a reconstruction of 16-sparseness 256-length ECG signal in 45μs with maximum operating frequency of 167MHz. When the sparseness is 8, it takes 18μs to recover the signal, which is 33% faster than the state-of-art design.
An Empirical Study on Industry Structure and Economic Growth——Based on the analysis of China,Guangdong and Guangzhou

This paper suggests an efficient indicator to measure the degree of industry structure upgrade,and uses it to do an empirical study on the industry structure and economic growth of China,Guangdong province and Guangzhou separately in the period of 1978 to 2009.The result shows that industry structure upgrades greatly in all of them and the same trend and feature are found.From country level to provincial level then to central city,economic growth advances industry structure,but the improvement from industry structure to economic growth is only found on central city level.
Neutrophil gelatinase-associated lipocalin (NGAL) as biomarker of acute kidney injury: a review of the laboratory characteristics and clinical evidences

Abstract Acute kidney injury (AKI) is a common and serious condition, currently diagnosed by functional biomarkers, such as serum creatinine measurements. Unfortunately, creatinine increase is a delayed and unreliable indicator of AKI. The lack of early biomarkers of structural kidney injury has hampered our ability to translate promising experimental therapies to human AKI. The recent discovery, translation and validation of neutrophil gelatinase-associated lipocalin (NGAL), possibly the most promising novel AKI biomarker, is reviewed here. NGAL may be measured by several methods both in plasma and urine for the early diagnosis of AKI and for the prediction of clinical outcomes, such as dialysis requirement and mortality, in several common clinical scenarios, including in the intensive care unit, cardiac surgery and renal damage due the exposition to toxic agent and drugs, and renal transplantation. Furthermore, the predictive properties of NGAL, may play a critical role in expediting the drug development process. A systematic review of literature data indicates that further studies are necessary to establish accurate reference population values according to age, gender and ethnicity, as well as reliable and specific decisional values concerning the more common clinical settings related to AKI. Furthermore, proper randomized clinical trials on renal and systemic outcomes comparing the use of NGAL vs. standard clinical practice are still lacking and accurate cost-benefit and/or cost-utility analyses for NGAL as biomarker of AKI are also needed. However, it is important to note that NGAL, in the absence of diagnostic increases in serum creatinine, is able to detect some patients affected by subclinical AKI who have an increased risk of adverse outcomes. These results also suggest that the concept and definition of AKI might need to be reassessed.
Optimal Price Design in the Wholesale Electricity Market

In this paper, we construct an optimal price design mechanism to determine the equilibrium in the day-ahead electricity market, specifically aimed at solving the uncomfortable conflict between conventional thermal sources (CTS) and renewable energy sources (RES). We find that the actual hourly market design is inadequate to achieve an efficient solution in the presence of a large and increasing share of RES. It is not conducive to catalyzing the correct price signal for future investments and does not take into account welfare considerations. Our proposal for a new market design is based on three main pillars. We state pro-competitive incentives to CTS participation in the market. We take into full account the opportunity cost of RES for society and propose correct price signals on the demand side through an optimal Ramsey pricing scheme. We show an empirical application to the Italian electricity market, using empirical measures of LCOE for RES and empirical estimation of heterogeneous buyers' behavior. The results show improvement in efficiency and welfare in the Italian electricity market with respect to the existing zonal market prices for suppliers and uniform price for buyers.
On Object Systems and Behavioral Inheritance

We consider state-based behavior in object-oriented analysis and design, as it arises, for example, in specifying behavior in the UML using statecharts. We first provide a rigorous and analyzable model of object systems and their reactivity. The definition is for basic one-thread systems, but can be extended in appropriate ways to more elaborate models. We then address the notion of inheritance and behavioral conformity and the resulting substitutability of classes, whereby inheriting should retain the system's original behaviors. Inheritance is a central issue of crucial importance to the modeling, design, and verification of object-oriented systems, and the many deep and unresolved questions around it cannot be addressed without a precise definition of the systems under consideration. We use our definition to give a clear and rigorous picture of what exactly is meant by behavioral conformity and how computationally complex it is to detect.