Miracle-dz/UniFAR-FTUs huggingface dataset:
Is There a Value Problem

This Article pre-print is brought to you for free and open access by the Philosophy at Digital Commons @ Loyola Marymount University and Loyola Law School. It has been accepted for inclusion in Philosophy Faculty Works by an authorized administrator of Digital Commons@Loyola Marymount University and Loyola Law School. For more information, please contact digitalcommons@lmu.edu. Repository Citation Baehr, Jason, "Is There a Value Problem? " (2009). Philosophy Faculty Works. 18. http://digitalcommons.lmu.edu/phil_fac/18
Child Sexual Abuse in Asian American Families: An Examination of Cultural Factors That Influence Prevalence, Identification, and Treatment

Child sexual abuse affects thousands of families each year. Issues pertaining to the prevalence, identification, and treatment of sexual abuse have been relatively well explored in the literature as they pertain to the dominant European American culture. These issues, however, are still relatively unexplored in terms of how sexual abuse affects Asian American families and the Asian American community. We review the relevant literature in Asian American families. These matters are explored in the context of Asian American values such as collectivity, conformity, inconspicuousness, middle position virtue, shame, self-control, and fatalism. Attitudes toward family, sexuality, and the mental health system are also discussed. Cultural and institutional barriers to underutilizing mental health services are also explored, and suggestions for overcoming these barriers are offered.
Processes Regulating Cervical Ripening Differ From Cervical Dilation and Postpartum Repair: Insights From Gene Expression Studies

A greater understanding of the processes that regulate cervical remodeling during pregnancy, parturition, and the postpartum period is required to understand causes of preterm and posterm birth in which abnormal cervical function is the primary culprit. In the current study, gene expression patterns unique to cervical ripening as compared with cervical dilation and/or postpartum repair are identified in a mouse model. Genes differentially regulated from gestation day 15 to late day 18 reveal processes important for cervical ripening. Genes differentially regulated from late day 18 to 2 hours after birth reveal processes that could be important during cervical dilation or the postpartum recovery period. Based on expression patterns, cervical ripening requires a downregulation of collagen assembly genes; increased synthesis of glycosaminoglycans that disrupt the matrix, such as hyaluronan; increased metabolism of progesterone; and changes in epithelial barrier properties. The latter phases of dilation and postpartum recovery are associated with increased assembly of mature collagen, synthesis of matrix proteins that promote a dense connective tissue, activation of inflammatory responses, prostaglandin synthesis, and further changes in epithelial barrier properties and differentiation. Processes/gene expression required for cervical ripening are distinct from those important in latter phases of cervical remodeling and highlight the importance of timing of tissue collection for understanding the molecular mechanisms of cervical ripening.
Network cross-validation by edge sampling

While many statistical models and methods are now available for network analysis, resampling of network data remains a challenging problem. Cross-validation is a useful general tool for model selection and parameter tuning, but it is not directly applicable to networks since splitting network nodes into groups requires deleting edges and destroys some of the network structure. In this paper we propose a new network resampling strategy, based on splitting node pairs rather than nodes, that is applicable to cross-validation for a wide range of network model selection tasks. We provide theoretical justification for our method in a general setting and examples of how the method can be used in specific network model selection and parameter tuning tasks. Numerical results on simulated networks and on a statisticians’ citation network show that the proposed cross-validation approach works well for model selection.
Repérage et extraction de terminologie par une approche mixte statistique et linguistique

Dans le cadre de la construction automatique de banques terminologiques, l'A. a elabore une methode d'extraction a partir de corpus qui combine donnees linguistiques et modeles statistiques. Une etude linguistique des termes du domaine technique des telecommunications a permis de mettre au point des filtres linguistiques charges d'extraire les sequences morphosyntaxiques decrivant les patrons categoriels des termes. Ces filtres permettent d'obtenir une premiere selection de sequences pouvant etre considerees comme des candidats termes et sur lesquelles sont appliquees divers modeles de statistiques lexicales
wrinkled 1 : A Novel , Low-Seed-Oil Mutant of Arabidopsis with a Deficiency in the Seed-Specific Regulation of Carbohydrate Metabolism 1

During oil deposition in developing seeds of Arabidopsis, photosynthate is imported in the form of carbohydrates into the embryo and converted to triacylglycerols. To identify genes essential for this process and to investigate the molecular basis for the developmental regulation of oil accumulation, mutants producing wrinkled, incompletely filled seeds were isolated. A novel mutant locus, wrinkled1 (wri1), which maps to the bottom of chromosome 3 and causes an 80% reduction in seed oil content, was identified. Wildtype and homozygous wri1 mutant plantlets or mature plants were indistinguishable. However, developing homozygous wri1 seeds were impaired in the incorporation of sucrose and glucose into triacylglycerols, but incorporated pyruvate and acetate at an increased rate. Because the activities of several glycolytic enzymes, in particular hexokinase and pyrophosphate-dependent phosphofructokinase, are reduced in developing homozygous wri1 seeds, it is suggested that WRI1 is involved in the developmental regulation of carbohydrate metabolism during seed filling.
"This is My Story...": Storytelling with Tangible Artifacts among Migrant Women in Germany

This study explores the combination of tangible artifacts and digital storytelling as an enabling means for women from educationally disadvantaged communities to have their voices heard in (local) public discourse, and at the same time gain in eloquence with regard to speech and technology and media use. Results show how representative, yet personally meaningful tangible artifacts helped participants to voice experiences, develop computer skills and position themselves with regard to similarities and differences of their migration backgrounds and the host society.
Heterogeneity and stochastic growth regulation of biliary epithelial cells dictate dynamic epithelial tissue remodeling

Dynamic remodeling of the intrahepatic biliary epithelial tissue plays key roles in liver regeneration, yet the cellular basis for this process remains unclear. We took an unbiased approach based on in vivo clonal labeling and tracking of biliary epithelial cells in the three-dimensional landscape, in combination with mathematical simulation, to understand their mode of proliferation in a mouse liver injury model where the nascent biliary structure formed in a tissue-intrinsic manner. An apparent heterogeneity among biliary epithelial cells was observed: whereas most of the responders that entered the cell cycle upon injury exhibited a limited and tapering growth potential, a select population continued to proliferate, making a major contribution in sustaining the biliary expansion. Our study has highlighted a unique mode of epithelial tissue dynamics, which depends not on a hierarchical system driven by fixated stem cells, but rather, on a stochastically maintained progenitor population with persistent proliferative activity. DOI: http://dx.doi. org/10.7554/eLife.15034. 001
Attribute identification and predictive customisation using fuzzy clustering and genetic search for Industry 4.0 environments

Today s factory involves more services and customisation. A paradigm shift is towards “Industry 4.0” (i4) aiming at realising mass customisation at a mass production cost. However, there is a lack of tools for customer informatics. This paper addresses this issue and develops a predictive analytics framework integrating big data analysis and business informatics, using Computational Intelligence (CI). In particular, a fuzzy c-means is used for pattern recognition, as well as managing relevant big data for feeding potential customer needs and wants for improved productivity at the design stage for customised mass production. The selection of patterns from big data is performed using a genetic algorithm with fuzzy c-means, which helps with clustering and selection of optimal attributes. The case study shows that fuzzy c-means are able to assign new clusters with growing knowledge of customer needs and wants. The dataset has three types of entities: specification of various characteristics, assigned insurance risk rating, and normalised losses in use compared with other cars. The fuzzy c-means tool offers a number of features suitable for smart designs for an i4 environment.
Social Support and Suicide Potential: Preliminary Findings for Adolescent Populations

The relationship between both the quantity and perceived quality of social support and suicidal risk was examined in a sample of 50 adolescents whose ages ranged from 16 to 20 years. A multiple regression analysis was performed, using scores from Cull and Gill's 1983 Suicide Probability Scale as the criterion measure along with the predictor variables of quantity and quality of experienced social support as measured by the 1983 Social Support Questionnaire of Sarason, Levine, Basham, and Sarason. Analysis showed the social support variables accounted for over 52% of the variance in suicide potential. The greatest proportion of the variance in suicide risk was attributable to the quality of the perceived social support. Adolescents at greater risk for suicide were significantly less satisfied with the quality of their social support.
Analysis of spurious vowel-like regions (VLRs) detected by excitation source information

This work treats vowels and semivowels as vowellike regions. An analysis of the spurious vowel-like regions (VLRs) detected by a signal processing based method using excitation source information is demonstrated. Limitation of excitation information in detecting some of the nasals and voiced consonants as non-VLRs is discussed. An attempt to reduce spurious VLRs compared to the existing signal processing based method for VLRs detection [1] is made. A multi-class statistical phone classifier that classifies speech into broad vowel, consonant and silence categories is trained. The outputs of the classifier are suitably combined to get evidence for vowel-like regions, different broad categories of consonants and silence regions. The output from the existing signal processing method is compared with different evidences from the statistical method. The spurious ones are eliminated by using the evidences from the statistical method. The experimental studies conducted on TIMIT and inhouse databases demonstrate significant reduction in the spurious VLRs with a little loss in the VLRs detection performance. A net gain of 4.21% and 7.71% in frame error rate is achieved for TIMIT and in-house databases, respectively.
Detection of Mycoplasma pneumoniae in simulated clinical samples by Polymerase Chain Reaction

Polymerase chain reaction (PCR) was used to detect Mycoplasma (M) pneumoniae DNA in simulated clinical samples. Throat swabs were mixed with known amounts of broth‐grown M. pneumoniae cells. An estimated detection limit of less than 40 colony forming units (cfu) was obtained without the need for time‐consuming hybridization. The PCR is completed in one day and may be useful for the early detection of M. pnuemoniae in clinical samples.
A modularized two-stage charge equalization converter for series connected lithium-ion battery strings in an HEV

This paper proposes a modularized two-stage charge equalization converter for a series-connected lithium-ion battery string in an HEV. In this paper, the series-connected battery sting is modularized into M modules, and each module has K cells in series. With this modularization, low voltage stress on the electronic devices can be achieved. A two-stage dc-dc converter with cell selection switches is employed. The first stage dc-dc converter steps down the high bus voltage to about 10 V. The second stage dc-dc converter integrated with selection switches equalizes the cell voltages. A prototype for 88 lithium-ion battery cells is optimally designed and implemented. Experimental results verify that the proposed equalization method has good cell balancing performance showing low voltage stress, small size, and low cost.
Effect of gamma irradiation on reactivity of rinderpest virus antigen with bovine immune serum in enzyme-linked immunosorbent assays and virus neutralization and indirect fluorescent-antibody tests

Gamma irradiation effectively inactivated gradient-purified rinderpest virus. Irradiated antigen and sera remained functional in enzyme-linked immunosorbent assays, virus neutralization tests, and indirect fluorescent-antibody tests. Irradiation, however, led to a dose-dependent decrease in reactivity, particularly significant (P < 0.05) when both reagents were irradiated. To avoid false-positive reactions, only one reagent (serum or antigen) may be irradiated.
An Alternative Control Methodology to Complex System: Fuzzy Supervisory Indirect Learning Predictive Controller

In this paper, a fuzzy supervisory indirect learning predictive controller (FsiLPC) is proposed. The controller integrates the concepts of the conventional model based predictive control (MBPC), the controller output error method and the fuzzy rule based system. In contrast to the conventional MBPC, the design of FsiLPC is more generic in terms of model compatibility; the predictive model to be adopted in the scheme can be of any structure. The FsiLPC demonstrates a number of attractive characteristics for industrial implementation. These include flexibility of employing a predictive model, adaptive capability to the variation in the operating conditions, and simplicity of the operating mechanisms. The methodology is thus considered as a potential solution to the control of complex multi-input-multi-output (MIMO) systems. The strategy of the integration is first illustrated through an overview of the general architecture of the controller, followed by descriptions of the individual operating mechanism. Two case studies are investigated to evaluate the performances of the controller. The first case study describes the control of a simple system with non-minimum phase dynamics while the control of a multivariable industrial process of a single screw extruder is detailed in the second case study. The encouraging results stem the interest to further explore the applicability of the proposed controller for industrial uses.
Laser Scanning in Forests

The introduction of Airborne Laser Scanning (ALS) to forests has been revolutionary during the last decade. This development was facilitated by combining earlier ranging lidar discoveries [1–5], with experience obtained from full-waveform ranging radar [6,7] to new airborne laser scanning systems which had components such as a GNSS receiver (Global Navigation Satellite System), IMU (Inertial Measurement Unit) and a scanning mechanism. Since the first commercial ALS in 1994, new ALS-based forest inventory approaches have been reported feasible for operational activities [8–12]. ALS is currently operationally applied for stand level forest inventories, for example, in Nordic countries. In Finland alone, the adoption of ALS for forest data collection has led to an annual savings of around 20 M€/year, and the work is mainly done by companies instead of governmental organizations. In spite of the long implementation times and there being a limited tradition of making changes in the forest sector, laser scanning was commercially and operationally applied after about only one decade of research. When analyzing high-ranked journal papers from ISI Web of Science, the topic of laser scanning of forests has been the driving force for the whole laser scanning research society over the last decade. Thus, the topic “laser scanning in forests” has provided a significant industrial, societal and scientific impact. [. ]
Prevalence of subclinical atherosclerosis in asymptomatic diabetic patients by 64-slice computed tomography

ObjectivesPatients with diabetes have a 2-fold to 4-fold higher risk of a cardiovascular event than nondiabetic patients. Thus there is a need to identify patients with diabetes who are at risk of cardiovascular events before the onset of symptoms. We studied the prevalence of coronary artery disease in asymptomatic diabetic patients compared with asymptomatic nondiabetic patients by 64-slice computed tomography (CT). MethodsFrom 425 asymptomatic patients with coronary risk factors but without known coronary artery disease who underwent 64-slice CT, we identified 93 asymptomatic diabetic patients (diabetic group) and 93 age-matched and sex-matched asymptomatic nondiabetic patients. ResultsClinical characteristics were not significantly different between the two groups. Total coronary calcium score was significantly higher in diabetic group than that in nondiabetic group (median 117 vs. 53.5, P<0.0001). No coronary calcium was detected in 30.0% of nondiabetic group compared with 15.1% of diabetic group (P=0.0022). Coronary calcium score more than 400 was detected in 9.7% of nondiabetic group compared with 36.6% of diabetic group (P<0.0001). Coronary plaques were found in 67.7% of nondiabetic group compared with 91.4% of diabetic group (P<0.0001). Multiple plaques were detected in 57.0 and 77.4% of patients in nondiabetic and diabetic group, respectively (P=0.0030). Significant coronary stenosis was found in 16.1% of nondiabetic group compared with 33.3% of diabetic group (P=0.0065). ConclusionOur results show that the prevalence of coronary plaques detectable by 64-slice CT in asymptomatic diabetic patients is very high.
Defining a Point of Departure and Potency Estimates in Carcinogenic Dose Response

2.0 Points of Departure and Potency Estimates.3 2.1 The Benchmark Dose approach. 3 2.2 The T25 approach.7 2.3 Comparing BMD and T25 methodology for use in risk assessment.8 2.4 The TD50 approach.8 2.5 The NOAEL (No Observed Adverse Effect Level) approach.9
Service Quality Effects on Customer Loyalty among the Jordanian Telecom Sector "Empirical Study"

The challenging questions that face telecom managers are: How customers perceive and judge service quality in mobile telecom industry? Also, how can they build loyalty by choice? The prime objective of this study is to analyze the Service Quality Effects on Customer Loyalty in the Jordanian Telecom Sector. The population of this study is IT and MIS university students. The prime criterions behind it are that these students are a target market for the telecom organizations and more attracted to advertisement and promotional activities. The study used descriptive analysis, one way ANOVA, Pearson Correlation, and finally stepwise regression analysis was calculated to assess the impact of SERVQUAL factors on customer loyalty. The statistical results of Pearson correlation (0.626) indicate a strong and positive correlation between SERVQUAL and customer loyalty in the Jordanian telecom market. Also, the Study found that SERVQUAL had a significant impact at level (P? 0.05) on customer loyalty in the Jordanian telecom market. In addition, the study showed that Durbin-Watson value forthe SERVQUAL was (1.901).
Mitochondrial AtTrxo1 is transcriptionally regulated by AtbZIP9 and AtAZF2 and affects seed germination under saline conditions

&NA; Mitochondrial thioredoxin‐o (AtTrxo1) was characterized and its expression examined in different organs of Arabidopsis thaliana. AtTrxo1 transcript levels were particularly high in dry seeds and cotyledons where they reached a maximum 36 h after imbibition with water, coinciding with 50% germination. Expression was lower in seeds germinating in 100 mM NaCl. To gain insight into the transcriptional regulation of the AtTrxo1 gene, a phylogenomic analysis was coupled with the screening of an arrayed library of Arabidopsis transcription factors in yeast. The basic leucine zipper AtbZIP9 and the zinc finger protein AZF2 were identified as putative transcriptional regulators. Transcript regulation of AtbZIP9 and AtAFZ2 during germination was compatible with the proposed role in transcriptional regulation of AtTrxo1. Transient over‐expression of AtbZIP9 and AtAZF2 in Nicotiana benthamiana leaves demonstrated an activation effect of AtbZIP9 and a repressor effect of AtAZF2 on AtTrxo1 promoter‐driven reporter expression. Although moderate concentrations of salt delayed germination in Arabidopsis wild‐type seeds, those of two different AtTrxo1 knock‐out mutants germinated faster and accumulated higher H2O2 levels than the wild‐type. All these data indicate that AtTrxo1 has a role in redox homeostasis during seed germination under salt conditions.
A 2 Gb/s 21 CH low-latency transceiver circuit for inter-processor communication

A 20-data-channel transceiver with a control channel allows uncoded data transfer with 13 ns latency. A digital DLL with a ring-interpolator tracks phase with 20 ps resolution. A pre-emphasis driver enables 2 Gb/s transmission per channel over a 7 m cable at 1.5 V. The effective full-duplex bandwidth reaches 10 GB/s.
Rac1 Signaling Modulates BCL-6-Mediated Repression of Gene Transcription

ABSTRACT Rac1 is a member of the Rho family of small GTPases that not only regulates signaling pathways involved in cell adhesion and migration but also regulates gene transcription. Here we show that the transcriptional repressor BCL-6 is regulated by Rac1 signaling. Transfection of active Rac1 mutants into colorectal DLD-1 cells led to increased expression of a BCL-6-controlled luciferase reporter construct. Conversely, inhibition of endogenous Rac1 activation by the Rac1 inhibitor NSC23766 decreased reporter activity. Moreover, BCL-6 lost its typical localization to nuclear dots upon activation of Rac1 and became predominantly soluble in a non-chromatin-bound cell fraction. Rac1 signaling also regulated the expression of endogenous BCL-6-regulated genes, including the p50 precursor NF-κB1/p105 and the cell adhesion molecule CD44. Interestingly, these effects were not stimulated by the alternative splice variant Rac1b. The mechanism of BCL-6 inhibition does not involve formation of a stable Rac1/BCL-6 complex and is independent of Rac-induced reactive oxygen species production or Jun NH2-terminal kinase activation. We show that PAK1 mediates inhibition downstream of Rac and can directly phosphorylate BCL-6. Together, these data provide substantial evidence that Rac1 signaling inhibits the transcriptional repressor BCL-6 in colorectal cells and reveal a novel pathway that links Rac1 signaling to the regulation of gene transcription.