Miracle-dz/UniFAR-FTUs huggingface dataset:
Study of South Pole ice transparency with IceCube ﬂashers

: The IceCube observatory, 1 km 3 in size, is now complete with 86 strings deployed in the antarctic ice. IceCube detects the Cherenkov radiation emitted by charged particles passing through or created in the ice. To realize the full potential of the detector the properties of light propagation in the ice in and around the detector must thus be known to the best achievable accuracy. This report presents a new method of ﬁtting the ice model to a data set of in-situ light source events collected with IceCube. The resulting set of derived ice parameters is presented and a comparison of IceCube data with simulation based on the new model is shown.
A complementary hybrid classification algorithm based on Web text

In view of the insufficiency of existing weight computation methods and SVM algorithm, a weight computation method of variable precision rough set based on Web text and a complementary hybrid classification algorithm are proposed; In the hybrid classification algorithm, the rough set is used as a front-end processor of SVM, the traditional SVM is optimized from classification efficiency and precision through the reduction theory and weight computation method proposed in this paper. The experimental results show that the reduced and weighted data are classified using SVM, and then the performance of classification is further guaranteed.
STUDY OF THE VARIABILITY OF WIND ENERGY RESOURCES IN ROMANIA

The main objective of the present work is to provide an extensive and more comprehensive picture of the wind patterns in Romania. The wind conditions were evaluated in order to cover large areas of the Romanian lands and, also, areas belonging to the Romanian nearshore. Moreover, a direct comparison between these areas was performed. The wind conditions are mainly evaluated by considering the AVISO satellite measurements, which correspond to the time interval 2010-2015. This data set is also completed by 15-year period of reanalysis of the wind data (2000-2014) coming from the European Centre for Medium-Range Weather Forecasts. The main conclusion of this work is that the Romanian lands, as well as its nearshore, are appropriate for the wind energy extraction. Moreover, it seems that the future of the renewable energy extraction is in the coastal environment. This is because the wind energy is higher in the marine areas, it can be combined with some other sources as the wave energy in hybrid approaches and, finaly, the marine energy farms can also help in the coastal protetction, which represents, in fact, a very challenging issue.
An Examination of The Mediating Role of Job Satisfaction on The Relationship Between Psychological Empowerment and Innovative Behavior

As a result of environmental changes and global competition, the ambition to reveal innovative employees has enhanced the interest and significance of psychological empowerment. This study investigates the mediating role of job satisfaction on the relationship between psychological empowerment and innovative behavior. Data were collected from employees working in 4 and 5 star tourism certificated hotel businesses in Nevsehir, Turkey. The findings of the research showed that there was a significant and positive relationship among psychological empowerment, job satisfaction and innovative behavior. Besides, job satisfaction partially mediated the relationship between psychological empowerment and innovative behavior. Finally, limitations and research recommendations are discussed.
Exosome release of ADAM15 and the functional implications of human macrophage‐derived ADAM15 exosomes

A disintegrin and metalloproteinase 15 (ADAM15), the only ADAM protein containing an Arg‐Gly‐Asp (RGD) motif in its disintegrin‐like domain, is a widely expressed membrane protein that is involved in tumor progression and suppression. However, the underlying mechanism of ADAM15‐mediated tumor suppression is not clearly understood. This study demonstrates that ADAM15 is released as an exosomal component, and ADAM15 exosomes exert tumor suppressive activities. We found that exosomal ADAM15 release is stimulated by phorbol 12‐myristate 13‐acetate, a typical protein kinase C activator, in various tumor cell types, and this results in a corresponding decrease in plasma membrane‐associated ADAM15. Exosomes rich in ADAM15 display enhanced binding affinity for integrin αvβ3 in an RGD‐dependent manner and suppress vitronectin‐ and fibronectin‐induced cell adhesion, growth, and migration, as well as in vivo tumor growth. Exosomal ADAM15 is released from human macrophages, and macrophage‐derived ADAM15 exosomes have tumor inhibitory effects. This work suggests a primary role of ADAM15 for exosome‐mediated tumor suppression, as well as functional significance of exosomal ADAM protein in antitumor immunity. —Lee, H. D. , Koo, B. ‐H. , Kim, Y. H. , Jeon, O. ‐H. , Kim, D. ‐S. Exosome release of ADAM15 and the functional implications of human macrophage‐derived ADAM15 exosomes. FASEB J. 26, 3084–3095 (2012). www.fasebj. org
Cluster-than-Label: Semi-Supervised Approach for Domain Adaptation

The performance of a conventional machine learning the model trained on a source domain degrades poorly when they are tested on a different data distribution (target domain). These traditional models deal with this problem by training a new paradigm for the particular different data distribution (target domain). Therefore, training of a new paradigm forthe individual data distribution is computationally expensive. This paper demonstrates that how to adapt to a new data distribution (target domain), utilising the model trained on the source domain and avoiding the cost of re-training and the need for access to the source labelled data. In particular, we introduce an Efficient Semi-supervised Cluster-than-Label Cross-domain Adaptation Algorithm (SCTLCDA) to address the cross-domain adaptation classification problem in which we utilised both labelled and unlabelled data samples in the target domain, as well as completely unlabelled data samples in the source domain. Subsequently, we also describe that our proposed method can manage large datasets and easily lead to cross-domain adaptation problem. The effectiveness and performance of our method are confirmed by experiments on two real-world applications: Cross-domain sentiments and Web-Spam classification problem.
N-grams and the clustering of registers

This paper explores the use of different-length n-grams as a basis for identifying relationships between registers. Using the BNC Baby and the ICE-GB corpora as test cases, we study the following questions in a principled rigorously bottom-up fashion: (i) how well can n-grams distinguish parts in corpora? (ii) how much do corpus parts derived from n-grams correspond to registers or sub-registers as defined by corpus compilers? (iii) which n-gram length yields the best discriminatory power? (iv) how many n-grams yield the best discriminatory power? In contrast with most previous studies, we use hierarchical agglomerative cluster analyses to cluster sub-corpora and use average silhouette widths as a diagnostic to decide on how many clusters to distinguish. *
A high efficiency AC-DC charge pump using feedback compensation technique

This paper presents a high performance AC-DC charge pump for RFID tags, with the self-bias feedback and threshold compensation technique. Compared with conventional charge pump, the influence of threshold is greatly reduced and output DC voltage and power conversion efficiency is greatly improved. This proposed charge pump with 5 stages is implemented in SMIC 0.18 mum standard CMOS process. Simulation and measurement results show that for sinusoidal wave (f = 3.56 MHz) with magnitude voltages of 0.5 V, 0.6 V, and 0.7 V the output DC voltages of 1.1 V, 1.5 V and 1.9 V can be generated respectively with 120 KOmega equivalent load. Measurement results show the power conversion efficiency (PCE) reaches as high as 36%. And the sensitivity performance of RFID tags is improved to as low as -14.5 dBm.
Functional impairment of the HIPK 2 small ubiquitin-like modifier ( SUMO )-interacting motif in acute myeloid leukemia

Covalent conjugations of the SUMO-1 moiety on a target protein play important roles in the regulation of cellular protein function. SUMO-conjugation of PML is a regulatory step for PML nuclear body (PML-NB) formation, and HIPK2 is SUMO-conjugated and recruited into the PML-NBs. Although HIPK2 mutations (R861W and N951I) were found in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) patients, little is known about the underlying mechanisms by which HIPK2 mutations are associated with the pathogenesis of leukemia. Here we show that HIPK2 mutants found in AML and MDS patients are defective in SUMO-interacting motif (SIM) function. Due to defective SIM function, the HIPK2 mutants were not modified with SUMO-1, and not recruited to the PMLNBs. However, the HIPK2 mutants can normally bind to and phosphorylate AML1b. Therefore, the HIPK2 mutants can sequestrate the AML1 complex out of the PML-NBs, resulting in the disruption of AML1-mediated activation of target genes for myeloid differentiation. In addition, the differentiation of K562 blast cells was impaired by the expression of the HIPK2 SIM-defective mutants. These results suggest that HIPK2 targeting into the PML-NBs via the SIMs is crucial for HIPK2-mediated induction of myeloid differentiation, and is associated with AML pathogenesis.
Using advanced InSAR techniques as a remote tool for mine site monitoring

Advanced Interferometric synthetic aperture radar (InSAR) techniques are capable of measuring and accurately characterizing ground deformation due to their unique capacity to provide dense point clouds of deformation measurements coupled with a history of movement over time. Recently, remote monitoring of ground deformation from radar satellites has become an operational tool for mines world-wide. While InSAR techniques have long been able to provide accurate deformation rates over a mine’s total surface assets, results were not available at a reporting frequency short enough to meet operational planning and monitoring needs. Satellite observations were limited to time intervals of 24, 35, or even 46 days. Now with 16-, 11-, 8-, and even 4-day revisit times of current modern satellites, the data collection cycle has vastly improved. The reporting time cycle has also improved with advanced InSAR techniques and tools that can process the increased data loads and provide critical deformation information to the geotechnical departments on operational planning time schedules. This paper covers the advances made in the InSAR-derived products and services designed for the mining industry. Case studies presented include two African open pits monitored for surface changes due to mining operations, as well as deformation affecting waste piles and tailing dams. Subsidence due to underground coal excavation in Poland is being analysed. An example of monitoring surface infrastructure and tailings facilities over an active block cave operation is also presented.
The heart failure and obesity paradox : would you suggest your patients gain weight ?

Ischemic heart disease (IHD) is the leading cause of death and disability worldwide. For patients presenting with an acute ST-segment elevation myocardial infarction (STEMI, the major cause of which is an acute thrombotic coronary arterial occlusion), the most effective therapeutic strategy for limiting myocardial infarct (MI) size, preserving left ventricular systolic function and improving clinical outcomes, is by timely myocardial reperfusion using primary percutaneous coronary intervention (PPCI) to remove the obstruction. However, restoring blood flow in the infarct-related coronary artery comes at a price, as the process of myocardial reperfusion can in itself paradoxically inflict further injury to the myocardium—a phenomenon which has been termed “myocardial reperfusion injury. ” Myocardial reperfusion injury results in myocardial stunning, reperfusion arrhythmias, microvascular obstruction and cardiomyocyte death, and its presence contributes up to 50% of the final MI size. Although the process of myocardial reperfusion by PPCI continues to be improved with recent advances in PCI technology, anti-platelet and anti-thrombotic therapy, there currently exist no effective therapy for preventing myocardial reperfusion injury. Therefore, novel therapeutic interventions, which are capable of reducing myocardial reperfusion injury, are needed to further reduce MI size, prevent the onset of heart failure and improve clinical outcomes in STEMI patients undergoing PPCI. In this article, a brief overview of myocardial reperfusion injury will be provided with special emphasis on its magnitude and relevance to clinical cardiology practice today.
Real-coded genetic algorithm with oriented evolution towards promising region for parameter optimization

In this paper, a novel real-coded genetic algorithm is presented to generate offspring towards a promising polygon field with k+1 vertex, which represents a set of promising points in the entire population at a particular generation. A set of 19 test problems available in the global parameter optimization literature is used to test the performance of the proposed real-coded genetic algorithms. Several performance comparisons with five significant real-coded genetic algorithms, three state-of-the-art differential evolution algorithms and three others significant evolutionary computing techniques are performed. The comparative study shows the proposed approach is statistically significantly better than or at least comparable to twelve significant evolutionary computing techniques over a test suite of 19 benchmark functions.
KINETIC PARAMETERS ESTIMATION IN A MTR RESEARCH AND PRODUCTION REACTOR IN SUBCRITICAL STATES

Subcritical measurements were performed for the first time at the RA-3 research and production reactor in order to obtain relevant kinetic parameters for the safe operation of the reactor. Measurements were made during the shut-down period in presence of high background gamma radiation (greater than 10 R/h) and xenon. At each stationary subcritical state, the neutron source was assumed to come from photoneutron precursors produced during the normal operation of the reactor. Kinetic parameters were estimated using both neutron noise and inverse kinetics techniques. It was possible to estimate the photoneutron effectiveness of the RA-3 reactor, giving a value of (1.11 ± 0.05) 10. Using the least squares inverse kinetics method the neutron source strength was estimated and then used in the inverse kinetics equation in order to get the reactivity evolution during the change of core configuration of the reactor. The study of the obtained experimental values shows the existence of spatial effects in the reactivity estimation, which were confirmed by numerical simulations carried out with the diffusive neutron code PUMA.
Evaluation of Iron Status in Anemia of Chronic Disease Among Patients With HIV Infection

OBJECTIVE: In HIV-infected populations from developing countries, it is unclear what proportion of anemia is attributable to iron deficiency (ID). The objective of this study was to evaluate the iron status in anemia of chronic disease of patients with Human Immunodeficiency Virus (HIV) infection attending Federal Medical Centre, Makurdi. DESIGN AND SETTING: A total of 312 subjects comprising of 207 confirmed HIV positive patients and 105 apparently healthy subjects as control were evaluated for indices of anemia using SYSMEX KX 21N hematology analyzer machine (Kobe, Japan), CD4 count using CYFLOW SL machine (Artec, Germany), and total iron binding capacity and serum iron using colorimetric method. RESULTS: While results showed that Serum Iron, Transferrin Saturation, PCV, RBC, MCV, MCH, MCHC and RDWCV are within normal reference range but statistically different (p<0.05) compared to the controls. Stratifying them on the basis of CD4 count showed that in AIDS patients the indicators are generally lower with Hb, PCV, MCH and RDWCV showing statistical significance (p<0.05) compared with patients with CD4 >200cells/mm3. Serum iron (50%) and transferring saturation (47.9%) contributed highest to anemia prevalence especially in males while Hb concentration (47.2%) is the major contributor to anemia in females. CONCLUSION: It was concluded therefore that albeit, on average, the parameters of iron status did not indicate iron deficiency or iron overload in the HIV-status groups and AIDS patients, a large percentage of patients did have anemia of chronic disease with HIV-infected women afflicted more often. The anemia is generally normocytic hypochromic in AIDS patients.
Epicatalysis in a Simple Mechanical-Gravitational System: A Second-Law Paradox?

Catalysis is usually construed to facilitate equilibrium being attained more easily and quickly, or occasionally less so (anticatalysis), but not to alter the position of equilibrium, i.e., not to alter the equilibrium constant Keq. Indeed, it is sometimes stated that if catalysis could alter Keq, then it could be employed to violate the Second Law of Thermodynamics. Nevertheless, cases wherein catalysis does alter Keq are known. This has been dubbed epicatalysis. A violation of the Second Law via epicatalysis is precluded if it costs at least as much work to restore the catalyst (specifically, the epicatalyst) to its initial state as can be yielded by the alteration of Keq that it can achieve. In most cases of epicatalysis, it does cost at least as much work usually more work to restore the catalyst (specifically, the epicatalyst) to its initial state as can be yielded by the alteration of Keq that it can achieve. Yet recently systems and processes entailing epicatalysis have been investigated for which this may not be true, and hence which may challenge the Second Law. In this paper we investigate a system wherein catalysis alters Keq, yet wherein at least prima facie there seems to be at least in principle zero thermodynamic cost-zero required work for withdrawal and re-insertion of catalysis. Since chemical systems and reactions can be complex, in this paper we instead investigate a simple mechanical-gravitational system that may serve to illustrate the principles more transparently. This system consists a gas particle (e.g., molecule, Brownian particle, etc.) capable of moving within and between two gravitational potential wells separated by a barrier, in a uniform gravitational field.
Historical and Ecological Factors Affecting Regional Patterns of Endemism and Species Richness: The Case of Squamates in China

Biogeography is closely tied to both ecology and phylogenetic biology and its main areas of interest are ecological biogeography, i.e. the study of factors influencing the present distribu‐ tion, and historical biogeography, i.e. the study of causes that have operated in the past [1]. Ecological and historical biogeography therefore applies different concepts in order to explain the distribution of organisms. The former deals with functional groups of species and envi‐ ronmental constraints, whereas the latter focuses on taxonomic groups and historical biogeo‐ graphical events [2]. Recently, the division between historical and ecological biogeography has been considered as an obstacle to the progress of biogeography and some authors have stressed the benefits of integrating these two points of view [1,3-4]. In this context, the present work attempts at integrating these two approaches to explore the regional patterns of endemism and species richness of the squamates(lizards and snakes) in China.
Healthy Habits, Holy Habits: Spirituality's Relationship to College Students' Health

The current study examined the relationship between spirituality and college students’ health behaviors and beliefs. As participants, the researcher selected one thousand twenty undergraduate students who previously participated in Wave 3 of the National Study of Youth and Religion (NSYR) Wave 3. The researcher used the NSYR Wave 3 archival data to find descriptive statistics, as well as obtain students’ level of spirituality and specific college student health behaviors and beliefs. The study supported and contradicted previous literature related to college students’ spirituality and health behaviors and beliefs. The significance of the study helps higher education professionals understand the role of spirituality in the health of undergraduate students.
Prevalence of Dyslipidemia in Urban and Rural Areas of the Northwest of Iran: The Sociodemographic, Dietary and Psychological Determinants

Background: As dyslipidemia is a preventable risk factor for Coronary heart disease (CHD), precise estimation of its prevalence and determinants is crucial for proper development of health actions. This population-based study aimed at investigating the socioeconomic, dietary and psychological determinants of dyslipidemia in Iran. Methods: The data (n=700) for this study were collected in 2015 as a part of the major Lifestyle Promotion Project (LPP) conducted in East Azerbaijan (urban and regional parts). The data for socio-demographic status, dietary information, and physical activity and anxiety levels were collected through validated questionnaires. Then, physical examinations including blood pressure, body mass index (BMI) and conicity index were performed. The levels of serum lipids were measured by enzymatic colorimetric methods. Results: The prevalence of hypercholesterolemia, high LDL-C, hypertriglyceridemia, low HDL-C and dyslipidemia was 29.4%, 10.3%, 62.3%, 41.4%, 83.3% respectively. The mean TC (184.3±41.2 vs. 174.5±38.1 mg/dl), LDL-C (94.6±30.3 vs. 88.1±28.7 mg/dl) and HDL-C (46.7±10.4 vs. 39.5±8.0 mg/dl) in women were significantly higher than men (P<0.05). However, the mean of TG (182.3±119.3 vs. 145.1±87.8 mg/dl) was significantly higher in men compared to women (P<0.05). Obesity, family history of dyslipidemia, sedentary lifestyle, smoking habits, salt intake, and anxiety were risk factors for different components of dyslipidemia in men and women. Conclusion: Dyslipidemia is a major health problem in northwest of Iran. Focusing on screening, regular drug intake, proper nutrition, physical activity, and changing lifestyles of patients with dyslipidemia are essential.
Thermodynamic vs. Kinetic Basis for Polymorph Selection

Ratios of equilibrium solubilities rarely exceed two-fold for polymorph pairs. A model has been developed based on two intrinsic properties of polymorph pairs, namely the ratio of equilibrium solubilities of the individual pairs (C*me/C*st) and the ratio of interfacial energies (γst/γme) and one applied experimental condition, namely the supersaturation identifies which one of a pair of polymorphs nucleates first. A domain diagram has been developed, which identifies the point where the critical free energy of nucleation for the polymorph pair are identical. Essentially, for a system supersaturated with respect to both polymorphs, the model identifies that low supersaturation with respect to the stable polymorph (Sst) leads to an extremely small supersaturation with respect to the metastable polymorph (Sme), radically driving up the critical free energy with respect to the metastable polymorph. Generally, high supersaturations sometimes much higher than the upper limit of the metastable zone, are required to kinetically favour the metastable polymorph.