Miracle-dz/UniFAR-FTUs huggingface dataset:
Supporting Run-Time Evolution in Seescoa

In this paper, the SEESCOA component model and its run-time system are presented. In the SEESCOA-project, a component methodology was developed that explicitly models component interaction using the port and connector concepts. Since non-functional constraints are important for embedded systems, they are modelled separately in contracts. Using this component interaction model, SEESCOA allows for dynamic component reconfiguration. A detailed description is given on both the process of a component upgrade and the required changes to the run-time architecture. Furthermore, important concepts in the domain of live updates relevant to SEESCOA are given.
Residual stress field analysis of Al/steel butt joint using laser welding–brazing

ABSTRACT The objective of this study is to analyse residual stress of the Al/steel butt joint using the laser welding–brazing. The welding parameters were a laser power of 1200 W, a welding speed of 600 mm min−1, thickness of 150×150×2 mm and 150×150×1 mm, respectively. The residual stress was measured by the hole-drilling methods. Then, a finite-element model of the welding process was established, and it was verified by experiments. The results show that the calculated results are in conformity with the experimental results. The longitudinal residual stress on the galvanised steel (329 MPa) is larger than that on the aluminium alloy (293 MPa). At the location of the fixture, the longitudinal residual stress is substantially zero.
Crystal structure of bis{4-bromo-2-[(carbamimidamidoimino)methyl]phenolato-κ3 N,N′,O}cobalt(III) nitrate dimethylformamide monosolvate

In [Co(C8H8BrN4O)2]NO3·C3H7NO, the ligand molecules are deprotonated at the phenol O atom and octahedrally coordinate the CoIII atoms through the azomethine N and phenolate O atoms in a mer configuration. In the crystal lattice, the cations are arranged in layers in the ab plane divided by the nitrate anions and solvent molecules. All of the amine H atoms are involved in hydrogen bonding to nitrate, DMF or ligand O atoms or to one of the Br atoms, forming two-dimensional networks.
Nitric Oxide Alleviated Arsenic Toxicity by Modulation of Antioxidants and Thiol Metabolism in Rice (Oryza sativa L.)

Nitric oxide (NO) is a gaseous signaling molecule and has a profound impact on plant growth and development. It is reported to serve as pro oxidant as well as antioxidant in plant system. In the present study, we evaluated the protective role of NO against arsenate (AsV) toxicity in rice plants. AsV exposure has hampered the plant growth, reduced the chlorophyll content, and enhanced the oxidative stress, while the exogenous NO supplementation has reverted these symptoms. NO supplementation has reduced the arsenic (As) accumulation in root as well as shoot. NO supplementation to AsV exposed plants has reduced the gene expression level of OsLsi1 and OsLsi2. AsV stress significantly impacted thiol metabolism, it reduced GSH content and GSH/GSSG ratio, and enhanced the level of PCs. NO supplementation maintained the GSH/GSSG ratio and reduced the level of PCs. NO supplementation reverted AsV induced iron deficiency in shoot and had significant impact of gene expression level of various iron transporters (OsYSL2, OsFRDL1, OsIRT1, and OsIRO2). Conclusively, exogenous application of NO could be advantageous against AsV toxicity and could confer the tolerance to AsV stress in rice.
sranjans : Semantic Textual Similarity using Maximal Weighted Bipartite Graph Matching

The paper aims to come up with a system that examines the degree of semantic equivalence between two sentences. At the core of the paper is the attempt to grade the similarity of two sentences by finding the maximal weighted bipartite match between the tokens of the two sentences. The tokens include single words, or multi-words in case of Named Entitites, adjectivally and numerically modified words. Two token similarity measures are used for the task - WordNet based similarity, and a statistical word similarity measure which overcomes the shortcomings of WordNet based similarity. As part of three systems created for the task, we explore a simple bag of words tokenization scheme, a more careful tokenization scheme which captures named entities, times, dates, monetary entities etc., and finally try to capture context around tokens using grammatical dependencies.
On the nature of radial transport across sheared zonal flows in electrostatic ion-temperature-gradient gyrokinetic tokamak plasma turbulence

It is argued that the usual understanding of the suppression of radial turbulent transport across a sheared zonal flow based on a reduction in effective transport coefficients is, by itself, incomplete. By means of toroidal gyrokinetic simulations of electrostatic, ion-temperature-gradient turbulence, it is found instead that the character of the radial transport is altered fundamentally by the presence of a sheared zonal flow, changing from diffusive to anticorrelated and subdiffusive. Furthermore, if the flows are self-consistently driven by the turbulence via the Reynolds stresses (in contrast to being induced externally), radial transport becomes non-Gaussian as well. These results warrant a reevaluation of the traditional description of radial transport across sheared flows in tokamaks via effective transport coefficients, suggesting that such description is oversimplified and poorly captures the underlying dynamics, which may in turn compromise its predictive capabilities.
Rational Timber Frame Structure Jointed with Glass Fiber Reinforced Nylon Plate I : Basic shear properties of a drift-pin joint to static loads

In order to develope a rational joint system in traditionally joined timber frame structures, we designed a new drift-pin joint composed of a steel pipe drift-pin with a glass-fibre-reinforced nylon (GFRP) plate inserted into a slit of the timber. Lateral resistance tests of the joint with a single drift-pin were conducted to evaluate the effects of dorift-pin shape on maximum and yield loads. These properties were compared with a common drift-pin joint with a steel plate. The joint with a nylon plate had 60% of the stiffness, 90% of the maximum load and 90% of the yield load as compared to a steel plate. Both nylon and steel plate joints with steel pipe drift-pins had 80% of the lateral strength of common drift-pins. Maximum and yield loads of nylon plate joints with steel pipe drift-pins under reversed cyclic loads were equivalent to those under monotonic loads, and no failure of nylon plate had occured under reversed cyclic loads at the yield resistance level after 150 cycles.
Use of mchI Encoding Immunity to the Antimicrobial Peptide Microcin H47 as a Plasmid Selection Marker in Attenuated Bacterial Live Vectors

ABSTRACT Live attenuated bacterial strains expressing heterologous antigens represent an attractive vaccine development strategy. However, the use of drug resistance genes for the selection of expression plasmids introduced into live vectors poses theoretical health risks. Therefore, we developed a novel approach for plasmid selection based on immunity to the antimicrobial peptide microcin H47 (MccH47). Two expression plasmids encoding the reporter green fluorescent protein (GFPuv) were constructed; selection markers comprised either mchI, conferring immunity to MccH47 (pGEN222I), or bla (encoding β-lactamase), conferring conventional resistance to ampicillin (pGEN222). GFPuv-specific serum immunoglobulin G (IgG) antibody responses were analyzed in mice immunized intranasally either with Salmonella enterica serovar Typhi CVD 908-htrA or Shigella flexneri 2a CVD 1208S live vector and were boosted parenterally with purified GFPuv. Similar IgG antibody responses were observed for both pGEN222 and pGEN222I when either CVD 1208S or CVD 908-htrA(pGEN222I) was used as the carrier. Interestingly, CVD 908-htrA(pGEN222I) elicited a significantly higher IgG response than CVD 908-htrA(pGEN222). We also compared the priming potential of homologous priming either with CVD 908-htrA(pGEN222I) or CVD 1208S(pGEN222I) to heterologous priming first with CVD 908-htrA(pGEN222I) and then with CVD 1208S(pGEN222I) and vice versa. Immunization with two unrelated live vectors significantly enhanced the IgG responses compared to responses engendered by homologous CVD 908-htrA(pGEN222I) but not to those of CVD 1208S(pGEN222I). MccH47 offers an alternate system for plasmid selection in bacterial live vectors that greatly improves their clinical acceptability. Furthermore, the success of the heterologous priming strategy supports the feasibility of the future development of multivalent live vector-based immunization strategies against multiple human pathogens.
GENOMIC ANALYSIS OF CANCER AND HUMAN GENETIC DISORDERS

The Wigler and Hicks group studies human cancer and genetic disorders from a population genomics perspective. The cancer effort focuses on breast and prostate cancer (the latter jointly with Lloyd Trotman) and involves col­ laborative clinical studies (with local, national, and inter­ national collaborators) to discover mutational patterns predicting treatment response and outcome. We also de­ velop methodology for single-cell genomic and RNA analyses to detea cancer cells in bodily fluids such as blood and urine. This last has major potential applications to the early detection of cancer and monitoring its recurrence and response to therapy during and after treatment. The single-cell analysis has also led to insights about the clonal evolution and heterogeneity of cancers (Navin et al. 2011). This work may lead to a better understanding of initia­ tion, progression, and metastasis and shed light on the stem cell hypothesis of cancer and host responses. Our genetic efforts are largely focused on determining the role of new (de novo) mutation in pediatric disorders with a strong genetic contribution. We study autism as part of a large study of simplex families organized by the Simons Foundation (Fischbach and Lord 2010), as well as congenital heart disease with Dorothy Warburton of Columbia University and pediatric cancers with Ken Offit of Memorial Sloan-Kettering Cancer Center (MSKCC). In collaboration with Alea Mills, we helped create a mouse model for one of the most common ge­ netic abnormalities contributing to autism (Horev et al. 2011). Recent work has confirmed and extended our previous observations on the role of de novo copy-number variation (large-scale mutation) in autism (Levy et al. 2011), with similar results in the other disorders. In a large-scale exome sequencing project in collaboration with Dick McCombie (at the Genome Center at CSHL) and the Genome Sequencing Center at Washington Uni­ versity in St. Louis, we have proven the role of small-scale de novo mutations that disrupt genes in autism (Iossifov et al. 2012). Overall, our results succeed in confirming our previous genetic models for autism incidence and identify strong candidate mutational targets, from which biological models of autism can be made and tested. Breaking with tradition, the remainder of this report contains two position statements on the direction in which we are taking our science, and why.
URANIUM TETRAFLUORIDE THERMOPHYSICAL PROPERTIES MEASUREMENTS BY THE LASER FLASH METHOD

In order to increase the efficiency of the metalothermic reduction process employed by the IPEN-Instituto de Pesquisas Energeticas e Nucleares, to produce metallic uranium by means of uranium tetrafluoride reduction with magnesium, is planned utilize a mathematical model that numerically simulates the heat distribution in the charge of powders of uranium tetrafluoride and metallic magnesium duly blended. Because this program requires as input data the thermal conductivity of the uranium tetrafluoride powder and this data was not found in the literature, pellets were produced by uniaxialy pressing the uranium tetrafluoride powder in pellets, employing the same technology developed at CDTN-Centro de Desenvolvimento da Tecnologia Nuclear, to produce nuclear fuel pellets. The thermophysical properties of these pellets were measured at the LMPT - Laboratorio de Medicao de Propriedades Termofisicas de Combustiveis Nucleares e Materiais of CDTN applying the laser flash method. From the measurements results, it was possible to obtain an extrapolated value of ca. 0.24 Wm -1 K -1 for the thermal conductivity of the UF4 powder sample in the loose state and at room temperature. This value will be employed as input data of the mathematical model, whose results will be subject of a future publication. The UF4 powder pelletizing parameters and the thermophysical properties results (density, thermal diffusivity and thermal conductivity), are reported.
NetPhosBac – A predictor for Ser/Thr phosphorylation sites in bacterial proteins

There is ample evidence for the involvement of protein phosphorylation on serine/threonine/tyrosine in bacterial signaling and regulation, but very few exact phosphorylation sites have been experimentally determined. Recently, gel‐free high accuracy MS studies reported over 150 phosphorylation sites in two bacterial model organisms Bacillus subtilis and Escherichia coli. Interestingly, the analysis of these phosphorylation sites revealed that most of them are not characteristic for eukaryotic‐type protein kinases, which explains the poor performance of eukaryotic data‐trained phosphorylation predictors on bacterial systems. We used these large bacterial datasets and neural network algorithms to create the first bacteria‐specific protein phosphorylation predictor: NetPhosBac. With respect to predicting bacterial phosphorylation sites, NetPhosBac significantly outperformed all benchmark predictors. Moreover, NetPhosBac predictions of phosphorylation sites in E. coli proteins were experimentally verified on protein and site‐specific levels. In conclusion, NetPhosBac clearly illustrates the advantage of taxa‐specific predictors and we hope it will provide a useful asset to the microbiological community.
Physical Performance Assessment in Military Service Members

&NA; Few established measures allow effective quantification of physical performance in severely injured service members. We sought to establish preliminary normative data in 180 healthy, active‐duty service members for physical performance measures that can be readily implemented in a clinical setting. Interrater and test‐retest reliability and minimal detectable change (MDC) values were also determined. Physical performance testing included self‐selected walking velocity on level and uneven terrain, timed stair ascent, the sit‐to‐stand five times test, the four‐square step test, and the 6‐minute walk test. Data analysis included descriptive statistics, intraclass correlation coefficients, and MDC. Interrater and test‐retest reliability were excellent for all measures (intraclass correlation coefficients >0.75). MDC values for timed measures were <0.3 seconds for interrater comparisons and <1.5 seconds for between‐day comparisons. Physical performance measures had a narrow range of normal performance and were reliable and stable between days.
Representation and detection of deformable shapes

We present a method for detecting deformable shapes in images. The main difficulty with deformable template models is the very large (or infinite) number of possible nonrigid transformations of the templates. This makes the problem of finding an optimal match of a deformable template to an image incredibly hard. Using a new representation for deformable shapes we show how to efficiently find a global optimal solution to the nonrigid matching problem. Our matching algorithm can minimize a large class of energy functions, making it applicable to a wide range of problems. We present experimental results of detecting shapes in medical and natural images. Because we do not rely on local search techniques, our method is very robust, yielding good matches even in images with high clutter.
A rapid synthesis of blue-pigment copper cyclotetraphosphate (Cu2P4O12) rice- like grain nanoparticles at low temperature

Warunthip Chatjuthamanee, Rangson Muanghlua, Banjong Boonchom* and Naratip Vittayakorn Department of Chemistry, Faculty of Engineering, Rajamangala University of Technology Isan Khon Kaen Campus, Khon Kaen 40000, Thailand Department f Electronics, Faculty of Engineering, King Mongkuts Institute of Technology Ladkrabang, Bangkok 10520, Thailand King Mongkut’s Institute of Technology Ladkrabang, Chumphon Campus, 17/1 M. 6 Pha Thiew District, Chumphon, 86160, Thailand Advanced Materials Science Research Unit, Department of Chemistry, Faculty of Science, King Mongkut’s Institute of Technology Ladkrabang, Bangkok 10520, Thailand Electroceramic Research Laboratory, College of KMITL Nanotechnology, King Mongkut’s Institute of Technology Ladkrabang, Bangkok 10520, Thailand
Nano-Resolution Connectomics Using Large-Volume Electron Microscopy

The brain is organized into functionally and topographically specific areas. This functional distinction among brain regions is mainly achieved by different types of neurons (e.g., excitatory and inhibitory), their relative abundance in each area, and their specific local and long-distance connectivity. In the central nervous system, synapses are specialized junctions that permit a neuron to send chemical signals to another neuron. The human brain is estimated to have a hundred billion neurons and a thousand trillion synaptic connections. This vastly interconnected network of neurons is highly plastic in structure and function during development, learning, and memory, and is believed to make us unique individuals. More than a century ago, Santiago Ramón y Cajal demonstrated that neurons communicate with each other through syna pses using a light microscope and a silver staining technique discovered by Camillo Golgi. In recognition of their pioneering work on the structure of the nervous system, the 1906 Nobel Prize in Physiology or Medicine was awarded jointly to Cajal and Golgi. Although Cajal’s neuron doctrine eventually became the foundation of modern neuroscience, its acceptance came very slowly due to the lasting debates between the two scientists about the basic structure of the nervous system as well as the lack of a sufficiently advanced microscopic technology to resolve subsynaptic elements. Indeed, the first indisputable morphological evidence for synaptic contacts came in the 1950s with the newly-developed transmission electron microscopy (TEM) (Blackstad, 1965). Since then, EM has been established as a valuable tool for examining ultrastructural characteristics of neurons, synapses, and subcellular organelles. Subsequent technical advances in specimen preparation and instrumentation made it possible to explore the small-scale three-dimensional (3D) composition of nervous system using serial section EM (Harris et al., 1992; Sorra & Harris, 1993; Toni et al., 2001). However,
Etomidate speech and memory test (eSAM)

Background: The intracarotid amobarbital procedure (IAP) is an important part of comprehensive investigation of patients who are candidates for surgical treatment of epilepsy. Owing to repeated and lengthy shortages of amobarbital, causing delays in elective surgery, attempts have been made to find a suitable alternative anesthetic. The authors report their experience using etomidate, a widely used agent for the induction of anesthesia. Methods: Sixteen consecutive patients requiring IAP to evaluate memory or to lateralize speech underwent the procedure using etomidate. Prior to the procedure a catheter was placed in the internal carotid artery and an angiogram was performed. EEG was recorded and read online by an electroencephalographer. An anesthetist injected the drug, administered by bolus followed by an infusion, which was maintained until each speech measure had been sampled and new memory items had been introduced. The infusion was then stopped and testing continued as in a standard IAP. Results: In all cases (30 hemispheres) contralateral hemiplegia followed injection. EEG slow waves were observed in every injected hemisphere, with some contralateral slowing anteriorly in 18. Global aphasia with preserved attention and cooperation followed dominant-hemisphere injections. These phenomena remained during infusion, and upon its termination returned gradually to baseline over a period of about 4 minutes. Conclusions: Etomidate is a viable alternative to amobarbital, and its administration by bolus followed by infusion offers an improvement over the traditional intracarotid amobarbital procedure. Cognitive tests can be performed during an assured hemianesthesia of the injected hemisphere.
Czech Named Entity Corpus and SVM-based Recognizer

This paper deals with recognition of named entities in Czech texts. We present a recently released corpus of Czech sentences with manually annotated named entities, in which a rich two-level classification scheme was used. There are around 6000 sentences in the corpus with roughly 33000 marked named entity instances. We use the data for training and evaluating a named entity recognizer based on Support Vector Machine classification technique. The presented recognizer outperforms the results previously reported for NE recognition in Czech.
Audio Meta Data Transcription from Meeting Transcripts for the Continuous Media Web

The Continuous Media Web (CMWeb) integrates time{continuous media into the searching, linking, and browsing functionality of the World Wide Web. The le format underlying the CMWeb technology, Annodex, streams the media content multiplexed with XML{markup in the Continuous Media Markup Language (CMML). CMML contains information relevant to the whole media le (e.g., title, author, language) as well as time{sensitive information (e.g., topics, speakers, time{sensitive hyperlinks). This paper discusses the challenges of automatically generating Annodex streams from complex annotated recordings collected for use in linguistic research. We are particularly interested in annotated recordings of meetings and teleconferences and regard Annodex and its media browsing paradigm as a novel and rich way of interacting with such recordings. The paper presents our experiments with generating CMML and their corresponding Annodex les from hand annotated meeting recordings.
A simulation model for the Chikungunya with vectorial capacity

We have formulated a simulation model with base in non-linear ordinary differential equations following the formalism stated by Sir Ronald Ross for the Malaria, using the therm of incidence, the vectorial capacity of the Aedes aegypti and the sinusoidal-like temperature effect in the probabilities of virus transmission to the susceptible people and to the non-infected mosquitoes. We determine and simulate the vectorial capacity Cv(T ) and the epidemic threshold, Basic Reproduction Number, in terms of temperature R0(T ) and time R0(t). Moreover, we have simulated the infected population and female mosquito population carrying virus using Maple. The phase plane is obtained using previously reported data.
Multi-platform auto-vectorization

The recent proliferation of the single instruction multiple data (SIMD) model has lead to a wide variety of implementations. These have been incorporated into many platforms, from gaming machines and DSPs to general purpose architectures. In this paper, we present an automatic vectorizer as implemented in GCC, the most multi-targetable compiler available today. We discuss the considerations involved in developing a multi-platform vectorization technology, and demonstrate how our vectorization scheme is suited to a variety of SIMD architectures. Experiments on four different SIMD platforms demonstrate that our automatic vectorization scheme is able to efficiently support individual platforms, achieving significant speedups on key kernels.