Miracle-dz/UniFAR-FTUs huggingface dataset:
STANDARD AND HARMONIZE: TAX ARBITRAGE

In a globalized environment as the present, the question to ask is if the effects are possitive or negative. For this, in this document, we show a proposal that by Arbitrage Pricing Theory (APT), estimate prices arbitrage free interval, both gross value and net of tax. So, we check if the tax rules make arbitrage opportunities foreing to mechanism of markets, despite to bear in mind the liquidity risk. From these gross and net gap, we will estimate the standard and harmonize levels, and then, if market globalization goes with a suitable legal response.
Knowledge-sharing connections across geographical boundaries in global intra-firm networks

To boost project performance, managers of engineering and construction organizations are interested in sharing knowledge between employees across the organization. Global project-based organizations that operate in diverse markets are particularly keen to share knowledge collectively across projects and regions to gain a competitive advantage. Unfortunately, creating knowledge-sharing connections (KSCs) and knowledge-sharing networks (KSNs) can be particularly challenging for global project-based organizations. They face not only typical knowledge-sharing barriers of resources, organizational structures and individual motivations, but also physical and cultural barriers due to geographical distance. Although the benefits of global knowledge sharing are established, little is known about how KSCs and KSNs are established and maintained. In order to better understand the network structure and the formation of KSCs within these global organizations, the research analysed the KSC within a KSN focused on susta.
ESCAP: Towards the Design of an AI Architecture for a Virtual Counselor to Tackle Students' Exam Stress

Exam stress is a common predicament faced by students of all age groups and cultures. Unfortunately, it has neither created much consternation in the society nor attracted much interest for serious research, perhaps due to its impulsive causal nature that disappears almost instantly after the exams are over. Stress in optimal level can stimulate students to achieve their personal best in their exams. However, one of the greatest threats to the well-being of students arises due to the fallout of excessive stress, which, if not addressed timely may not only lead to failure in exams, but result in serious debilitating consequences including insomnia, depression and even suicide. Our research aims to design a human computer interaction (HCI) interface using artificial intelligence (AI) techniques for modeling a virtual exam-stress counsellor ESCAP, an embodied conversational agent with facial animation, advice and intelligence of a professional psychologist to support undergraduate students in managing their exam stress.
Does country-of-origin matter? a comparison study of the advanced vs. emerging and developing economies' consumer.

This paper identifies and explores whether the customers from advanced and emerging and developing economies have different perceptions towards country-of-origin of international branded clothes. It has been suggested that country-of-origin is commonly used by customers to predict a products quality and performance and to understand the rationality of their purchasing behaviour (Cai, Cude & Swagler 2004; Olins, 2004; Muchbalcher, Dahringer & Leihs, 1999). Products made in the advanced economies are often perceived to be more credible and appealing than products made in emerging economies (Anholt, 2006; Darling & Kraft, 1977; Usunier & Lee, 2005). However, cheaper production costs and a greater ability to outsource the manufacture of products has led made more and more international companies to source their products in emerging and developing countries (Gereffi & Memedovic, 2003). This phenomenon is the main reason for exploring whether customers in advanced and emerging and developing countries have different perception towards country-of-origin.
Conventional Weaning Parameters Do Not Predict Extubation Outcome in Intubated Subjects Requiring Prolonged Mechanical Ventilation

BACKGROUND: Approaches to respiratory care of patients needing prolonged mechanical ventilation (PMV) might be varied. In this study we assessed the predictive value of usual variables for extubation outcome in PMV patients. METHODS: From 2005 to 2007, intubated patients who were admitted to the intermediate respiratory care unit, had been on mechanical ventilation for ≥ 21 days at the time of admission, and underwent extubation after successful spontaneous breathing trials were included. Comparisons between subjects with successful extubation and failed extubation in terms of weaning parameters and clinical predictors of extubation outcome were performed. Also, 1-year survival of subjects with regard to extubation outcome was analyzed. RESULTS: Twenty-seven (23.7%) of 119 PMV subjects required reintubation within 7 days. Multivariate logistic regression analysis demonstrated that the only variable associated with extubation failure was ineffective cough (P < .001). Possessing 2 or more acceptable weaning parameters was not helpful in predicting extubation outcome. Subjects with failed extubation had worse 1-year survival (hazard ratio 0.49, 95% CI 0.28–0.87, P = .02) compared with those with successful extubation. CONCLUSIONS: In PMV subjects who tolerated spontaneous breathing trials and were ready to extubate, ineffective cough was the best predictor of extubation failure. Furthermore, extubation failure was associated with future mortality; thus, different management strategies need to be developed for improving patient outcome.
Dact gene expression profiles suggest a role for this gene family in integrating Wnt and TGF‐β signaling pathways during chicken limb development

Background: Dact gene family encodes multifunctional proteins that are important modulators of Wnt and TGF‐β signaling pathways. Given that these pathways coordinate multiple steps of limb development, we investigated the expression pattern of the two chicken Dact genes (Dact1 and Dact2) from early limb bud up to stages when several tissues are differentiating. Results: During early limb development (HH24‐HH30) Dact1 and Dact2 were mainly expressed in the cartilaginous rudiments of the appendicular skeleton and perichondrium, presenting expression profiles related, but distinct. At later stages of development (HH31–HH35), the main sites of Dact1 and Dact2 expression were the developing synovial joints. In this context, Dact1 expression was shown to co‐localize with regions enriched in the nuclear β‐catenin protein, such as developing joint capsule and interzone. In contrast, Dact2 expression was restricted to the interzone surrounding the domains of bmpR‐1b expression, a TGF‐β receptor with crucial roles during digit morphogenesis. Additional sites of Dact expression were the developing tendons and digit blastemas. Conclusions: Our data indicate that Dact genes are good candidates to modulate and, possibly, integrate Wnt and TGF‐β signaling during limb development, bringing new and interesting perspectives about the roles of Dact molecules in limb birth defects and human diseases. Developmental Dynamics 243:428–439, 2014. © 2013 Wiley Periodicals, Inc.
THE DESIGN OF AUTHENTICATED TELNET PROTOCOL TO ENHANCE CRYPTOGRAPHY AND SECURITY

In this paper, an authenticated TELNET protocol is proposed to establish TELNET connections with authentication and security. To achieve this goal, specific cryptographic algorithms and certificates are used to resist attacks such as eavesdropping, tampering, forgery and personating. The concept of designing this proposed protocol is to negotiate one cipher spec (one suite of cryptographic algorithm) and to generate the shared secret. Then, apply them to protect the communication securely. As for extensibility, this system also provides a framework by means of which new cryptographic algorithms can be incorporated if necessary. In consideration of compatibility issue, we define the command names and codes following the rules of the TELNET protocol. Overall, this system enhances the security of TELNET protocol with NMAC, and it is compatible with the current TELNET protocol.
Exploring SME market orientation: an organisational learning perspective

Purpose – The purpose of this paper is to develop and enhance organisational capability through learning within a small firm context. This paper forms part of a KTP project. The paper considers here traditional quantitative approaches (where data was gathered largely through questionnaires received from a single source within the firm) approaches for measuring market orientation against a mixed methods, organisation wide perspective. For achieving this task the role of mental models are considered and the perceptions and beliefs of individuals are translated with actual actions for gaining a more accurate picture of market orientation within the firm.Design/methodology/approach – Through a mixed methods approach a range of organisational data has been utilised to develop an understanding for not only the firms market orientation position, but also a much greater understanding of the composition of market orientation throughout the firm. Identifying differences in market orientation between departments as .
Thrombus Formation In a Living Mouse

Hemostasis and thrombosis are complex processes that involve the vessel wall, circulating blood cells, soluble blood coagulation and regulatory proteins, and blood cell-derived microparticles. Although previous work in this field has employed purified systems to parse this complexity and to allow development of models for the workings of these processes, it has become increasingly important to analyze hemostasis and thrombosis in a living animal where all of the components are present simultaneously. The development of knockout technology in the mouse and improvements in microscopic imaging instrumentation and high speed computers have allowed the development of a system for high speed intravital digital videomicroscopy in the microcirculation of a living mouse. The goal has been to visualize thrombus formation following vessel wall injury in the microcirculation of a living mouse using an intravital confocal and widefield microscopy imaging system. By revisiting and testing the models and hypotheses that have been developed from in vitro studies, we have been able to determine that many of these models and hypotheses are correct whereas some may need some significant modification. The study of biochemistry and cell biology in a living animal offers opportunities to understand physiology and pathology in complex biological systems. Over the years in vitro studies of blood coagulation and vascular biology have taught us what reactions and interactions can happen, but now it is time to learn what does happen in vivo. We have entered a new phase of discovery–an area that is developing rapidly: the ability to study thrombosis in living animals. Historically, our laboratory has employed biochemical, immunochemical and cell biology techniques to parse the mysteries of blood coagulation– with a special focus on the vitamin K-dependent blood coagulation proteins. When we surrendipitously discovered the protein now known as Pselectin [1], our work expanded to include platelets. Upon the discovery that P-selectin is an adhesion molecule that binds platelets to leukocytes [2] and the
Plasma exchange and heart–liver transplantation in a patient with homozygous familial hypercholesterolemia

A female patient born in 1950 underwent plasma exchange and concomitant drug therapy for 20 yr due to homozygous familial hypercholesterolemia. Plasma exchange reduced total cholesterol levels from 25–30 mmol/L (967–1160 mg/dL) before treatment to 9.5 mmol/L (363 mg/dL) with regression of xanthomas and no side effects of long‐term treatment. Due to end‐stage calcific left ventricular outflow tract obstruction not amenable to standard valve reconstructive surgery, a combined heart–liver transplantation was successfully performed in 1996. She is without symptoms and living a normal life 4 yr after transplantation. Total cholesterol value is normal (4.7 mmol/L [182 mg/dL]) using a moderate dose of statins. Selective coronary angiography is without signs of graft vascular disease and the liver function is normal.
A frequency-shift readout system for FPW allergy biosensor

In this paper, an IgE antigen concentration measurement system using a frequency-shift readout method for a two-port FPW (flexural plate-wave) allergy biosensor is presented. The proposed frequency-shift readout method adopts a peak detecting scheme to detect the resonant frequency. A linear frequency generator, a pair of peak detectors, two registers, and an subtractor are only needed in our system. According to the specification of the FPW allergy biosensor, the frequency sweep range is limited in 2 MHz to 10 MHz. The sensitivity of the peak detector is 0.8 mV. The proposed frequency-shift readout circuit is verified on silicon by using a standard 0.18 µm CMOS technology. The maximal power consumption is 12.94 mW@0.1 MHz clock given by HSPICE simulations.
A novel PAX1 null homozygous mutation in autosomal recessive otofaciocervical syndrome associated with severe combined immunodeficiency

Otofaciocervical syndrome (OFCS) is a rare disorder characterized by facial anomalies, cup‐shaped low‐set ears, preauricular fistulas, hearing loss, branchial defects, skeletal anomalies, and mild intellectual disability. Autosomal dominant cases are caused by deletions or point mutations of EYA1. A single family with an autosomal recessive form of OFCS and a homozygous missense mutation in PAX1 gene has been described.
2.45 GHz, 100 Mbps BPSK-DSSS transmitter for interference-robust wireless neuroprosthetic networks

We present a 2.45 GHz 100 Mbps transmitter for body-implantable wireless neuroprosthetic links. Binary phase-shift keyed (BPSK) modulation with direct sequence spread-spectrum (DSSS) signaling and a 32-bit wide pseudo noise (PN) code is used to create energy-efficient interference-robust communication link. Power consumption is minimized by using a novel transmission-gate based low-loss passive mixer and energy-efficient system integration. The phase-locked loop consumes only 700 μW with -118.7 dBc/Hz phase noise at 10 MHz offset and -51.5 dBc reference spur. The transmitter consumes 17 pJ/b at a data-rate of 100 Mbps with -11 dBm of output power.
EDI Implementation: The EDI Clusters Program in Greece

The rapid change in technology and other skills added to customers requiring highly specific and customized products, has lead to the need for far greater cooperation within and between firms. Electronic Data Interchange (EDI) is one of the tools that can help and change the way in which many companies communicate between each other. In this paper, the introduction and adoption of EDI in Greek companies are examined with a focus on the EDI Clusters Program. The objectives and management of the program, the profile of the participating companies, the barriers and the benefits during the preimplementation and the implementation stages are analyzed. According to the findings, the main problems of EDI implementation are mainly related to legal issues due to lack of institutional framework, to organizational and human where lack of experience in the management of funded projects, and coordination difficulties were the main obstacles. Additionally, different administrative and information technology environments, required reengineering of the business processes, but with insufficient training created insecurities, resistance to change and poor users commitment. Due to the above obstacles benefits realized were fewer than anticipated and are mostly operational, such as fo rmulation and realization of business processes, motivation for communication with business partners and upgrade of technological and organizational infrastructure.
Exploring a new jellyfish collagen in the production of microparticles for protein delivery

A microparticulate protein delivery system was developed using collagen, from the medusa Catostylus tagi, as a polymeric matrix. Collagen microparticles (CMPs) were produced by an emulsification-gelation-solvent extraction method and a high loading efficiency was found for the entrapment of lysozyme and α-lactalbumin. CMPs were cross-linked with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC). The uncross-linked CMPs were spherical, rough-surfaced, presenting an estimated median size of 28 µm by laser diffraction. Upon cross-linking, particle size (9.5 µm) and size distribution were reduced. CMPs showed a moderate hydrophobic behaviour and a positive surface charge. Cross-linking also resulted in greater stability in water, allowing a slow release, as shown by in vitro experiments. The assessment of lysozyme's biological activity showed that the protein remained active throughout the encapsulation and cross-linking processes. In summary, the work herein described shows the potential use of a marine collagen in the production of microparticles for the controlled release of therapeutic proteins.
Cloud Storage: Adoption, Practice and Deployment

Note: The information and recommendations made by Storage Strategies NOW, Inc. are based upon public information and sources and may also include personal opinions both of Storage Strategies NOW and others, all of which we believe are accurate and reliable. As market conditions change however and not within our control, the information and recommendations are made without warranty of any kind. All product names used and mentioned herein are the trademarks of their respective owners. Storage Strategies NOW, Inc. assumes no responsibility or liability for any damages whatsoever (including incidental, consequential or otherwise), caused by your use of, or reliance upon, the information and recommendations presented herein, nor for any inadvertent errors which may appear in this document.
Marine Bioremediation - A Sustainable Biotechnology of Petroleum Hydrocarbons Biodegradation in Coastal and Marine Environments

Bioremediation is now the best successful initiative to mitigate and to recover sites contaminated with hydrocarbons and has been the preferred process for clean-up contamination around the oceans of the world. The advantages of marine microorganisms in the removal of petroleum hydrocarbons, exemplifies the eco-sustainable bioremediation that can be achieved in sensitive marine environments and probably until now the only approach for biodiversity rich and fragile environments. The use of bio-surfactants to protect the marine environment is particularly attractive since a number of marine bacteria and microalgae strains can produce bio-surfactants during growth on hydrocarbons. Moreover, according to recent results, marine microorganisms, exhibit the maximum yield and surface-active property compared to terrestrial species. Because of the interest to find ecofriendly solutions for the bioremediation and biodegradation of petroleum hydrocarbons in the marine environment, the use of marine microorganisms and their respective bio-surfactants is preferable to that non-marine and of synthetic origin. The aim of this review is to integrate the advantages of marine bioremediation coupled to hydrocarbon removal from marine environments. This alternative of bioremediation is a natural process of waste treatment, relatively cost-effective than other remediation approaches that are used for clean-up of hazardous waste in coasts, seas and oceans that can be adaptable to variable environmental conditions, viz, estuarine, coastal and marine pollution and is widely accepted by the society.
Two new species of Plectranthias (Teleostei, Serranidae, Anthiadinae) from mesophotic coral ecosystems in the tropical Central Pacific

Abstract Two new species of Plectranthias perchlets are described, collected from mesophotic coral ecosystems in French Polynesia and the Republic of the Marshall Islands, in the tropical Central Pacific. Plectranthias polygoniussp. nov. was collected at a depth of 105 m in Tahiti, French Polynesia, and 120 m in Maloelap Atoll, Republic of the Marshall Islands. It was also observed in Moorea and Rangiroa (French Polynesia), and at Majuro and Erikub Atolls, Republic of the Marshall Islands. Plectranthias hinanosp. nov. was collected at a depth of 90–98 m in Tahiti, French Polynesia, and observed in Moorea. The barcode fragment of the cytochrome oxidase I gene of Plectranthias polygoniussp. nov. does not closely match any published sequence of Plectranthias, with approximately 15% uncorrected divergence from several species. Plectranthias polygoniussp. nov. can be distinguished from all of its congeners by coloration and morphology. The barcode fragment of the COI gene of Plectranthias hinanosp. nov. is closest to Plectranthias bennetti, with 5.4% uncorrected divergence. Plectranthias hinanosp. nov. is also distinguished from all of its congeners by morphology, and a coloration that includes two indistinct black spots along the base of the dorsal-fin, and transparent yellow dorsal and anal fin membranes. With this publication, the genus Plectranthias now comprises 58 valid species, with representatives from tropical to temperate waters of the Atlantic, Pacific, and Indian oceans. These two new discoveries add to the growing body of research highlighting the rich biodiversity of mesophotic ecosystems.
Highly‐efficient, fluorescent, locus directed cre and FlpO deleter mice on a pure C57BL/6N genetic background

To facilitate the use of the new mutant resource developed in the mouse, we have generated Cre and FlpO deleter mice on a pure inbred C57BL/6N background. The new transgenic constructs were designed to drive either the Cre or FlpO recombinase, fused to a specific fluorescent marker, respectively the eGFP or the eYFP, and were inserted by homologous recombination in the neutral Rosa26 locus. They allow a rapid, cost‐effective, and efficient identification of the carrier individuals through the coexpression of the fluorescent marker. The recombination efficiency of the two deleter lines, Gt(ROSA)26Sor and Gt(ROSA)26Sor, was carefully evaluated using five loxP‐flanked or four FRT‐flanked alleles located at different positions in the mouse genome. For each tested locus, we observed a 100% excision rate. The transgenic mice are easily distinguishable from wild type animals by their bright fluorescence that remains easily detectable until 10 days after birth. In the adult, fluorescence can still be detected inthe unpigmented paws. Furthermore, they both display accumulation of the specific recombinase during oogenesis. These fluorescent ‘Cre‐ and Flp‐ deleter’ transgenic lines are valuable tools for the scientific community by their high and stable recombination efficiency, the simplicity of genotype identification and the maintenance of a pure genetic background when used to remove specific selection cassette or to induce complete loss‐of‐function allele. genesis 50:482–489, 2012. © 2012 Wiley Periodicals, Inc.