Miracle-dz/UniFAR-FTUs huggingface dataset:
Identificação automática de construções de estrutura argumental: um experimento a partir da modelagem linguístico-computacional das construções transitiva direta ativa, ergativa e de argumento cindido

Este trabalho se enquadra dentro das discussoes teorico-metodologicas da FrameNet Brasil (FN-Br) e do Constructicon do portugues brasileiro e tem por objetivo (i) fornecer a modelagem linguistico-computacional necessaria para o tratamento das construcoes Transitiva Ativa, Ergativa e de Argumento Cindido no Constructicon do Portugues do Brasil; (ii) apresentar e discutir os resultados de uma tarefa de descoberta de construcoes por maquina cujo objetivo e o de identificar instâncias das construcoes acima; (iii) discutir as implicacoes desta tarefa para o desenvolvimento de constructicons. Dessa maneira, esta dissertacao busca embasamento na abordagem construcional da Berkeley Cunstruction Grammar proposta por Fillmore, Kay e O’Connor (1988), por Kay e Fillmore (1999) e Fillmore (2013). A nossa proposta se justifica pela escassez de estudos que integrem descricoes linguisticas com modelos de representacao computacionais cognitivamente plausiveis, possibilitando o tratamento de questoes que ultrapassam os modelos de representacao centrados exclusivamente em aspectos sintaticos . Nesse sentido, este trabalho se insere no âmbito da Linguistica Computacional, que, conforme afirma Dias da Silva (1996), envolve a integracao de questoes em tres dominios: linguistico, representacional e implementacional. Esta pesquisa se enquadra na fase representacional, uma vez que a fase linguistica ja foi proposta por Sampaio (2010), Ferreira (2009), Castilho (2010) e Perini (2010). Dado esse enquadramento, nosso objetivo foi modelar computacionalmente as construcoes Transitiva Ativa, Ergativa e CAC na base construcional da FrameNet, para que, posteriormente, na fase implementacional – nao desenvolvida nesta dissertacao, mas cujos resultados serao aqui discutidos – pudessem ser utilizadas em uma tarefa de descoberta construcional por maquina atraves do parser em desenvolvimento pela FN-Br, o CARMA.
Comparison of Business Motivation Model and Intentional Distribution Bachelor

Goal modelling is an important activity to reason why different software decisions are taken, or architecture solutions are implemented. Currently there exist a number of goal-oriented modelling approaches. In this thesis, the semiotic quality framework is applied to compare the quality of the business motivation model (BMM) and Intentional Distribution (i*) modelling languages at the coarse-grained level. The thesis reports on the BMM and i* language quality and model quality. The thesis also presents observations on how the BMM and i* modelling languages could be used to reason on and support construction of the business process models expressed in business processes model and notation.
Amplitude of the F wave

factor responsible for the stimulation of antimycin a-insensitive 0 2 consumption in preparations of liver mitochondria is not a fatty acid because the factor has been isolated and identified as uric acid (Biochem Biophys Res Commun, in press). So far as we can tell, uric acid is not causative of mitochondrial dysfunction. Elevated serum concentrations of both uric acid and free fatty acids in Reye syndrome are most likely secondary to a basic metabolic disturbance yet to be explained. However, the idea of looking for possible “toxins” in serum remains a valid approach, and we hope that studies of this type will continue.
Surveying the effects of CKMP of strategic managers on supply chain performance in Iran oil industry

The argument attempts to elaborate the study of the effect of collaborative knowledge management practice (CKMP) on supply chain performance (SCP) in Iranian oil industry to find out the relation of organisational infrastructure, and elements of knowledge management practice in Iranian oil industry. This study is conducted among the 120 managers who work at the oil companies. The self-administrated questionnaire was performed to gather data and to process and analyse the data descriptive and inferential statistics were used. The findings illustrated that the success of collaborative KMP is created on: 1) organisational factors like managerial engagement, supportive culture, employee devotedness; 2) technology capability to handle like large scale inter organisational system; 3) facilitating environmental factors like high operational uncertainty and collaborative trading partners; 4) compatible knowledge bases of all parties. Likewise, the outcome indicates that collaborating with each trading partners in KM can enhance the knowledge quality, integration with partners and SCP.
Modélisation unifiée du document et de son domaine pour une indexation par termes-clés libre et contrôlée (Unified document and domain-specific model for keyphrase extraction and assignment )[In French]

Dans cet article, nous nous intéressons à l’indexation de documents de domaines de spécialité par l’intermédiaire de leurs termes-clés. Plus particulièrement, nous nous intéressons à l’indexation telle qu’elle est réalisée par les documentalistes de bibliothèques numériques. Après analyse de la méthodologie de ces indexeurs professionnels, nous proposons une méthode à base de graphe combinant les informations présentes dans le document et la connaissance du domaine pour réaliser une indexation (hybride) libre et contrôlée. Notre méthode permet de proposer des termes-clés ne se trouvant pas nécessairement dans le document. Nos expériences montrent aussi que notre méthode surpasse significativement l’approche à base de graphe état de l’art.
© 2012 Landes Bioscience. Do not distribute. Additional cause for reduced JA-Ile in the root of a Lotus japonicus phyB mutant

Light is critical for supplying carbon for use in the energetically expensive process of nitrogen-fixing symbiosis between legumes and rhizobia. We recently showed that root nodule formation in phyB mutants [which have a constitutive shade avoidance syndrome (SAS) phenotype] was suppressed in white light, and that nodulation in wild-type is controlled by sensing the R/FR ratio through jasmonic acid (JA) signaling. We concluded that the cause of reduced root nodule formation in phyB mutants was the inhibition of JA-Ile production in root. Here we show that the shoot JA-Ile level of phyB mutants is higher than that of the wild-type strain MG20, suggesting that translocation of JA-Ile from shoot to root is impeded in the mutant. These results indicate that root nodule formation in phyB mutants is suppressed both by decreased JA-Ile production, caused by reduced JAR1 activity in root, and by reduced JA-Ile translocation from shoot to root. Light is an important environmental factor controlling plant growth. It is well known that plants require light for photosynthesis and are able to monitor both light quality and quantity for optimal survival. Plants have photoreceptors that sense the presence of their neighbors by monitoring the ratio of red light (R), which is absorbed by chlorophyll, and far red light (FR), which is not. A low R/FR ratio indicates the presence of neighbors that may compete for photosynthetically active radiation (PAR) and initiates the shade avoidance syndrome (SAS), causing plants to grow taller or bend to the light to avoid shade. 1-4 Many leguminous plants establish a symbiosis with nitrogenfixing soil bacteria called rhizobia. Inside the root nodules, the rhizobia differentiate into nitrogen-fixing bacteroids. The bacteroids convert atmospheric nitrogen into ammonia, a source of fixed nitrogen for the host plant. Because assimilates from photosynthesis provide energy to fuel the symbiosis between legumes and rhizobia, the light conditions under which host plants grow are very important. 5-8
Heat Pretreatment Alleviates UV‐B Toxicity in the Cyanobacterium Anabaena doliolum: A Proteomic Analysis of Cross Tolerance

This study offers proteomic elucidation of heat pretreatment‐induced alleviation of UV‐B toxicity in Anabaena doliolum. Heat‐pretreated cells exposed to UV‐B showed improved activity of PSI, PSII, whole chain, 14C fixation, ATP and NADPH contents compared to UV‐B alone. Proteomic analysis using two‐dimensional gel electrophoresis (2‐DE), MALDI‐TOF MS/MS and reverse transcription polymerase chain reaction (RT‐PCR) of UV‐B and heat pretreatment followed by UV‐B–treated cells exhibited significant and reproducible alterations in nine proteins homologous to phycocyanin‐α‐chain (PC‐α‐chain), phycoerythrocyanin‐α‐chain (PEC‐α‐chain), hypothetical protein alr0882, phycobilisome core component (PBS‐CC), iron superoxide dismutase (Fe‐SOD), fructose‐1,6‐bisphosphate aldolase (FBA), nucleoside diphosphate kinase (NDPK), phosphoribulokinase (PRK) and ribulose‐1,5‐bisphosphate carboxylase/oxygenase (RuBisCo) large chain. Except the PEC‐α‐chain, hypothetical protein alr0882 and PBS‐CC, all other proteins showed upregulation at low doses of UV‐B (U2) and significant downregulation at higher doses of UV‐B (U5). The disruption of redox status, signaling, pentose phosphate pathway and Calvin cycle appears to be due to the downregulation of Fe‐SOD, NDPK, FBA, PRK and RuBisCo thereby leading to the death of Anabaena. In contrast to this, the upregulation of all the above proteins in heat‐pretreated cells, harboring different heat shock proteins (HSPs) like 60, 26 and 16.6, followed by UV‐B treatment than only the UV‐B–treated ones suggests a protective role of HSPs in mitigating UV‐B toxicity.
Performance, gut morphology and carcass characteristics of fattening rabbits as affected by particle size of pelleted diets

A review of past literature revealed inconsistencies in recommended feed particle size for optimal growth and productive performance of rabbits. Changing diet formulation and subsequent processing conditions may improve pellet texture and potentially affect rabbit performance. In the current study, two isoenergetic and isonitrogenous pelleted diets were formulated, which varied in the particle size of the concentrates (2 and 8 mm, respectively). The objective was to evaluate the effect of different particle sizes of compound diets on performance, nutrient utilisation, gut morphology, and carcass characteristics of fattening Italian White breed rabbits. The finely ground diet led to a significant improvement in feed efficiency and apparent digestibility of crude protein, ether extract, crude fibre and NDF, without any negative effect on gut morphology. Furthermore, a smaller particle size of concentrates in pelleted diets improved carcass traits. Meat colour parameters showed significant differences in longissimus lumborum and biceps femoris due to dietary treatments, but in both muscles pH values 1 h and 24 h after slaughter remained unchanged. It is concluded that a finely ground pelleted diet can be used to improve growth performance of rabbits without affecting carcass parameters.
Determination of Plasma Protein S - The Protein Cofactor of Activated Protein C

Summary Protein S, an important cofactor of activated protein C, and C4b-binding protein were purified from human plasma. Specific antibodies against the purified proteins were raised in rabbits and used for the development of immunologic assays for these proteins in plasma: an immunoradiometric assay for protein S (which measures both free protein S and protein S complexed with C4b-binding protein) and an electroimmunoassay for C4b- binding protein. Ranges for the concentrations of these proteins were established in healthy volunteers and patients using oral anticoagulant therapy. A slight decrease in protein S antigen was observed in patients with liver disease (0.78 ± 0.25 U/ml); no significant decrease in protein S was observed in patients with DIC (0.95 ± 0.25 U/ml). Criteria were developed for the laboratory diagnosis of an isolated protein S deficiency
Entailment and relevance1

Those who object to the identification of strict implication and entail-ment speak in such a way that for A to entail B, A must be relevant to B. This view of entailment agrees not only with that of the naive student of logic (who tends to think the phrase paradoxes of “implication” more accurate than “paradoxes” of implication), but also with that expressed in the initial chapters of many textbooks in logic under the heading “Fallacies of Relevance. ”2 In regard to formal theories proposed as explications of the notion of entailment, it becomes important to have at our disposal some formal account of the demand for relevance as between antecedent and consequent of an entailment.
Preparation of cyclic peptide libraries using intramolecular oxime formation

A new method for the synthesis of cyclic head‐to‐side chain peptide libraries has been developed in which the key cyclization step involves reaction between a C‐terminal ketone and an N‐terminal hydroxylamine to form a macrocyclic oxime. This methodology efficiently delivers cyclic products that consist of mixtures of syn and anti isomers. Copyright © 2004 European Peptide Society and John Wiley & Sons, Ltd.
An MR protocol for presurgical evaluation of patients with complex partial seizures of temporal lobe origin.

PURPOSE To find an optimal diagnostic protocol for the presurgical MR evaluation of patients with temporal lobe epilepsy. METHODS MR imaging in 14 healthy subjects and 25 consecutive patients with temporal lobe epilepsy was performed in paracoronal sections perpendicular to the hippocampi with T1-weighted inversion recovery and T2 weighting. Volume measurements of the hippocampus/amygdala complex were performed and a multiecho sequence yielded T2-calculated images. RESULTS Hippocampal disease was seen in 22 of 25 temporal lobe epilepsy patients on paracoronal T1-weighted inversion recovery images. Four had bilateral abnormalities. Characteristic for hippocampal disease were features such as volume loss, decreased signal, and loss of internal morphology. Only 17 of 25 patients demonstrated hippocampal pathology on T2-weighted images, and in one patient this was bilateral. Patients with only minimal structural loss on T1-weighted inversion recovery had normal T2-weighted images. T2 calculation was no more sensitive than visual assessment on the T2-weighted images. Volume measurements were normal in one patient and misleading in two patients. Lateralization, as compared with clinical and electroencephalographic findings, was most confidently done with paracoronal T1-weighted inversion recovery images and volume measurements. CONCLUSIONS An optimum MR protocol for temporal lobe epilepsy patients is proposed. Its essential feature is that the hippocampus be evaluated by paracoronal T1-weighted inversion recovery images and volume measurements. T2-weighted imaging can be omitted.
Traitement des signaux parcimonieux et applications

Quel que soit le domaine d'application, il est necessaire de tirer profit de toute l'information a priori dans le but d'optimiser les resultats ou parfois meme de maniere a rendre un probleme soluble. Dans ce contexte, la notion de parcimonie a emerge comme un a priori fondamental ces dernieres annees. On dit qu'un signal est parcimonieux dans une base s'il peut etre decrit par un faible nombre de coefficients non nuls dans cette base. L'objet de cette these est l'etude de nouveaux apports de l'hypothese de parcimonie au traitement du signal. Deux domaines d'applications sont consideres. Outre l'utilisation de la parcimonie, ces deux domaines ont en commun la resolution de problemes inverses sous-determines. Le premier concerne la separation de sources. Dans ce domaine, la parcimonie a conduit au developpement de differentes methodes de separation de sources. Les performances de ces methodes sont sensibles au choix de certains parametres, habituellement choisis de maniere empirique. Dans cette these, on propose un formalisme statistique qui permet de reduire le nombre de ces parametres, tout en preservant la qualite de la separation. Le second domaine d'application etudie est l'acquisition compressee des signaux a alphabet fini. Une telle acquisition compressee permet de reduire la dimension des signaux a alphabet fini, tout en gardant l'information necessaire a leur reconstruction. Une formalisation du probleme permet de le relier a celui de la reconstruction des signaux parcimonieux a partir de mesures incompletes. Cette these est donc une exploration de nouvelles problematiques ou l'integration de la parcimonie conduit a de bonnes performances.
The role of growth hormone and glucocorticoid in glucose handling in vivo.

Growth hormone (GH) can oppose the catabolic effects of glucocorticoids. However, both hormones have adverse effects on carbohydrate metabolism. Here we examined the interactive effects of GH and the glucocorticoid methylprednisolone (MP) on glucose tolerance, insulin resistance and [3H]2,6-deoxyglucose uptake of peripheral tissues in rats. Female Wistar rats received either saline, GH (2.7 mg/kg), MP (5.0 mg/kg) or GH+MP. After 7 days treatment, animals were subjected to an i.v. glucose tolerance test. In a second experiment, animals treated as above were anesthetized and injected with human insulin (0.5 U/kg), [3H]2,6-deoxyglucose (500 microCi/kg), and [14C]mannitol (25 microCi/kg), to estimate insulin resistance and [3H]2,6-deoxyglucose uptake in fat and muscle. Weight gain in controls was 7.6+/-1.7 g, while GH treatment increased the mean body weight by 18.7+/-2.2 g (P<0.0002) and MP inhibited weight gain down to 0.0+/-1.0 g (P<0.004). This drop in weight gain was reversed back to normal when GH was given in combination with MP. After a glucose tolerance test no significant differences in glucose area under the curve were detected when comparing individual groups with the control group, but samples taken just before this test revealed that basal insulin was significantly elevated in the group treated with GH (174+/-27 pM, P<0.008), or GH+MP (209+/-21 pM, P<0.004), when compared with controls (107+/-17 pM). MP alone had no effect (122+/-19, P<0.3). After an i.v. bolus of insulin the group receiving GH+MP had a significantly (P<0.007) higher level of circulating glucose compared with controls (6.5+/-0.3 mM vs 4.4+/-0.7 mM). Despite this, there were no differences in peripheral glucose uptake between the two groups. In conclusion this study shows that a combined administration of GH and MP decreases the potency by which insulin decreases circulating glucose levels, but that peripheral tissues are not primarily involved in this insulin resistance.
Academy of Sciences of the Czech Republic Generalizations of the limited-memory BFGS method based on quasi-product form of update

Two families of limited-memory variable metric or quasi-Newton methods for unconstrained minimization based on quasi-product form of update are derived. As for the first family, four variants how to utilize the Strang recurrences for the Broyden class of variable metric updates are investigated; three of them use the same number of stored vectors as the limitedmemory BFGS method. Moreover, one of the variants does not require any additional matrix by vector multiplication. The second family uses vectors from the preceding iteration to construct a new class of variable metric updates. Resulting methods again require neither any additional matrix by vector multiplication nor any additional stored vector. Global convergence of four of presented methods is established for convex sufficiently smooth functions. Numerical results indicate that two of the new methods can save computational time substantially for certain problems.
Investigating Conversational Dynamics: Interactive Alignment, Interpersonal Synergy, and Collective Task Performance

This study investigates interpersonal processes underlying dialog by comparing two approaches, interactive alignment and interpersonal synergy, and assesses how they predict collective performance in a joint task. While the interactive alignment approach highlights imitative patterns between interlocutors, the synergy approach points to structural organization at the level of the interaction-such as complementary patterns straddling speech turns and interlocutors. We develop a general, quantitative method to assess lexical, prosodic, and speech/pause patterns related to the two approaches and their impact on collective performance in a corpus of task-oriented conversations. The results show statistical presence of patterns relevant for both approaches. However, synergetic aspects of dialog provide the best statistical predictors of collective performance and adding aspects of the alignment approach does not improve the model. This suggests that structural organization at the level of the interaction plays a crucial role in task-oriented conversations, possibly constraining and integrating processes related to alignment.
Mutation of a Single Envelope N-Linked Glycosylation Site Enhances the Pathogenicity of Bovine Leukemia Virus

ABSTRACT Viruses have coevolved with their host to ensure efficient replication and transmission without inducing excessive pathogenicity that would indirectly impair their persistence. This is exemplified by the bovine leukemia virus (BLV) system in which lymphoproliferative disorders develop in ruminants after latency periods of several years. In principle, the equilibrium reached between the virus and its host could be disrupted by emergence of more pathogenic strains. Intriguingly but fortunately, such a hyperpathogenic BLV strain was never observed in the field or designed in vitro. In this study, we sought to understand the role of envelope N-linked glycosylation with the hypothesis that this posttranslational modification could either favor BLV infection by allowing viral entry or allow immune escape by using glycans as a shield. Using reverse genetics of an infectious molecular provirus, we identified a N-linked envelope glycosylation site (N230) that limits viral replication and pathogenicity. Indeed, mutation N230E unexpectedly leads to enhanced fusogenicity and protein stability. IMPORTANCE Infection by retroviruses requires the interaction of the viral envelope protein (SU) with a membrane-associated receptor allowing fusion and release of the viral genomic RNA into the cell. We show that N-linked glycosylation of the bovine leukemia virus (BLV) SU protein is, as expected, essential for cell infection in vitro. Consistently, mutation of all glycosylation sites of a BLV provirus destroys infectivity in vivo. However, single mutations do not significantly modify replication in vivo. Instead, a particular mutation at SU codon 230 increases replication and accelerates pathogenesis. This unexpected observation has important consequences in terms of disease control and managing.
A Model for Recruiting Clinical Research Participants With Anxiety Disorders in the Absence of Service Provision: Visions, Challenges, and Norms Within a Canadian Context

Abstract High-quality research in clinical psychology often depends on recruiting adequate samples of clinical participants with formally diagnosed difficulties. This challenge is readily met within the context of a large treatment center, but many clinical researchers work in academic settings that do not feature a medical school, hospital connections, or an in-house clinic. This article describes the model we developed at the University of Waterloo Centre for Mental Health Research for identifying and recruiting large samples of people from local communities with diagnosable mental health problems who are willing to participate in research but for whom treatment services are not offered. We compare the diagnostic composition, symptom profile, and demographic characteristics of our participants with treatment-seeking samples recruited from large Canadian and American treatment centers. We conclude that the Anxiety Studies Division model represents a viable and valuable method for recruiting clinical participants from the community for psychopathology research.