Miracle-dz/UniFAR-FTUs huggingface dataset:
Patient and System-Related Delays of Emergency Medical Services Use in Acute ST-Elevation Myocardial Infarction: Results from the Third Gulf Registry of Acute Coronary Events (Gulf RACE-3Ps)

Background Little is known about Emergency Medical Services (EMS) use and pre-hospital triage of patients with acute ST-elevation myocardial infarction (STEMI) in Arabian Gulf countries. Methods Clinical arrival and acute care within 24 h of STEMI symptom onset were compared between patients transferred by EMS (Red Crescent and Inter-Hospital) and those transferred by non-EMS means. Data were retrieved from a prospective registry of 36 hospitals in 6 Arabian Gulf countries, from January 2014 to January 2015. Results We enrolled 2,928 patients; mean age, 52.7 (SD ±11.8) years; 90% men; and 61.7% non-Arabian Gulf citizens. Only 753 patients (25.7%) used EMS; which was mostly via Inter-Hospital EMS (22%) rather than direct transfer from the scene to the hospital by the Red Crescent (3.7%). Compared to the non-EMS group, the EMS group was more likely to arrive initially at a primary or secondary health care facility; thus, they had longer median symptom-onset-to-emergency department arrival times (218 vs. 158 min; p˂.001); they were more likely to receive primary percutaneous coronary interventions (62% vs. 40.5%, p = 0.02); they had shorter door-to-needle times (38 vs. 42 min; p = .04); and shorter door-to-balloon times (47 vs. 83 min; p˂.001). High EMS use was independently predicted mostly by primary/secondary school educational levels and low or moderate socioeconomic status. Low EMS use was predicted by a history of angina and history of percutaneous coronary intervention. The groups had similar in-hospital deaths and outcomes. Conclusion Most acute STEMI patients in the Arabian Gulf region did not use EMS services. Improving Red Crescent infrastructure, establishing integrated STEMI networks, and launching educational public campaigns are top health care system priorities.
Comparison research of two typical UML-class-diagram metrics: Experimental software engineering

Measuring UML class diagram complexity can help developers select one with lowest complexity from a variety of different designs with the same functionality; also provide guidance for developing high quality class diagrams. This paper compared the advantages and disadvantages of two typical class-diagram complexity metrics based on statistics and entropy-distance respectively from the view of newly experimental software engineering. 27 class diagrams related to the banking system were classified and predicted their understandability, analyzability and maintainability by means of algorithm C5.0 in well-known software SPSS Clementine. Results showed that UML class diagrams complexity metric based on statistics has higher classification accuracy than that based on entropy-distance.
Momentum picture of motion in Lagrangian quantum field theory

The basic aspects of the momentum picture of motion in Lagrangian quantum field theory are given. Under some assumptions, this picture is a 4-dimensional analogue of the Schr\"odinger picture: in it the field operators are constant, spacetime-independent, while the state vectors have a simple, exponential, spacetime-dependence. The role of these assumptions is analyzed. The Euler-Lagrange equations in momentum picture are derived and attention is paid on the conserved operators in it.
Feature vector classification by threshold for speaker identification

This paper describes a new feature vector classification method for speaker identification. Purpose of this paper is constructing robust speaker models which only use meaningful feature vectors and discard confusing feature vectors. To construct robust speaker model, proposed method classifies feature vectors using log-likelihood estimation. Experimental results, with various segments ranging from 0.25 to 5 s, showed that our method outperforms previous method.
Forced Homo- and Heterodimerization of All gp130-Type Receptor Complexes Leads to Constitutive Ligand-independent Signaling and Cytokine-independent Growth

We present a novel strategy to enforce cytokine-independent, constitutive signaling of heterodimeric gp130 receptor complexes. Replacing the extracellular domain of gp130-type receptors by IL-15/IL-15R is sufficient to heterodimerize gp130-like receptors and as a consequence leading to sustained cytokine-independent receptor activation.
Modeling of symmetric composite right/left-handed coplanar waveguides with applications to compact bandpass filters

This study proposes an equivalent-circuit model for the composite right/left-handed (CRLH) coplanar waveguide (CPW) comprising the series interdigital capacitor and shunt meandering short-circuited stub inductor in symmetric configuration. The new technique for extracting the equivalent-circuit elements of the CRLH CPW, which include inductances, capacitances, and resistances to represent the left-handed, right-handed, and lossy characteristics, is developed based on the effective medium concept. The applications to the compact resonators and filters are presented to emphasize the unique features of the CRLH CPW. A novel CRLH CPW resonator with a 0/spl deg/ effective electrical length at resonance is proposed, which gives a 49.1% size reduction when compared with the conventional half-wavelength resonator at 5 GHz. Based on the zeroth-order CRLH CPW resonators, an inductively coupled two-pole bandpass filter with 5.4% 3-dB bandwidth and 2.7-dB insertion loss at 5 GHz is implemented, and it is 51.4% more compact than the conventional structure. A good agreement among the results of the full-wave simulation, equivalent-circuit model, published data, and measurement demonstrates the effectiveness of the proposed modeling technique. To suppress the higher order harmonic spurious passbands, the electromagnetic-bandgap CPW structures are incorporated into the proposed CRLH CPW filter.
Topology-Based Hierarchical Clustering of Self-Organizing Maps

A powerful method in the analysis of datasets where there are many natural clusters with varying statistics such as different sizes, shapes, density distribution, overlaps, etc., is the use of self-organizing maps (SOMs). However, further processing tools, such as visualization and interactive clustering, are often necessary to capture the clusters from the learned SOM knowledge. A recent visualization scheme (CONNvis) and its interactive clustering utilize the data topology for SOM knowledge representation by using a connectivity matrix (a weighted Delaunay graph), CONN. In this paper, we propose an automated clustering method for SOMs, which is a hierarchical agglomerative clustering of CONN. We determine the number of clusters either by using cluster validity indices or by prior knowledge on the datasets. We show that, for the datasets used in this paper, data-topology-based hierarchical clustering can produce better partitioning than hierarchical clustering based solely on distance information.
Dual-band modified complementary split ring resonator (MCSRR) based multi-resonator circuit for chipless RFID tag

As chipless RFID technology has potential to offer ultra-low cost and fully printable tags, recently, there has been considerable interest on implementing a compact chipless RFID tag with adequate data capacity. In this paper, a compact multiresonator circuit for spectral signature based chipless RFID tag is proposed. The multiresonator circuit utilizes a number of modified complementary split ring resonators (MCSRR) placed along the transmission line as data bit encoding element. A novel resonance detuning mechanism proposed here allows the use of an MCSRR to independently encode two data bits instead of one bit. Besides, symmetricity of the MCSRR with respect to the feed line causes the disappearance of the second harmonic and hence the total realizable bandwidth for data bit encoding is also enhanced. The multiresonator circuit is based on coplanar waveguide (CPW) configuration and can be realized on flexible substrate with single sided metallization. Once incorporated with cross polarized UWB tag antennas, the proposed multiresonator circuit can be used for a compact fully printable chipless RFID tag that may replace barcode in the long run.
WING-IN-GROUND FLIGHT AUTOMATIC CONTROL SYSTEMS

Abstract Seaplanes and WIG-craft are supposed to take the significant part of the projected air traffic growth without constructing new airstrips. However, a trouble-free flight at low altitude over the disturbed sea surface and also marine landing require the application of the special methods and means of motion control which are capable to solve the corresponding specific problems. Methods of stability providing and solving some other problems of WIG flight by means of automatic control are analyzed1. The criteria for control systems improving are given. The experience and achievements in this field of high technology are described. Probable areas of the most effective application of vehicles with such equipment are indicated.
A muscle-specific transgenic reporter line of the sea anemone, Nematostella vectensis

The sea anemone, Nematostella vectensis, has become an attractive new model organism for comparative genomics and evolutionary developmental biology. Over the last few years, many genes have been isolated and their expression patterns studied to gain insight into their function. More recently, functional tools have been developed to manipulate gene function; however, most of these approaches rely on microinjection and are limited to early stages of development. Transgenic lines would significantly enhance the tractability of the system. In particular, the study of gene- or tissue-specific promoters would be most useful. Here we report the stable establishment of a transgenic line using the I-SceI meganuclease system to facilitate integration into the genome. We isolated a 1.6-kb fragment of the regulatory upstream region of the Myosin Heavy Chain1 (MyHC1) gene and found that the transgene is specifically expressed in the retractor and tentacle muscles of Nematostella polyps, faithfully reproducing the expression of the endogenous MyHC1 gene. This demonstrates that the 1.6-kb fragment contains all of the regulatory elements necessary to drive correct expression and suggests that retractor and tentacle muscles in Nematostella are distinct from other myoepithelial cells. The transgene is transmitted through the germline at high frequency, and G1 transgenic polyps have only one integration site. The relatively high frequency of transgenesis, in combination with gene- or tissue-specific promoters, will foster experimental possibilities for studying in vivo gene functions in gene regulatory networks and developmental processes in the nonbilaterian sea anemone, Nematostella vectensis.
Cell Division of Giardia intestinalis: Flagellar Developmental Cycle Involves Transformation and Exchange of Flagella between Mastigonts of a Diplomonad Cell

ABSTRACT Giardia intestinalis is a binucleated diplomonad possessing four pairs of flagella of distinct location and function. Its pathogenic potential depends on the integrity of a complex microtubular cytoskeleton that undergoes a profound but poorly understood reorganization during cell division. We examined the cell division of G. intestinalis with the aid of light and electron microscopy and immunofluorescence methods and present here new observations on the reorganization of the flagellar apparatus in the dividing Giardia. Our results demonstrated the presence of a flagellar maturation process during which the flagella migrate, assume different position, and transform to different flagellar types in progeny until their maturation is completed. For each newly assembled flagellum it takes three cell cycles to become mature. The mature flagellum of Giardia is the caudal one that possesses a privileged basal body at which the microtubules of the adhesive disk nucleate. In contrast to generally accepted assumption that each of the two diplomonad mastigonts develops separately, we found that they are developmentally linked, exchanging their cytoskeletal components at the early phase of mitosis. The presence of the flagellar maturation process in a metamonad protist Giardia suggests that the basal body or centriole maturation is a universal phenomenon that may represent one of the core processes in a eukaryotic cell.
An activated triple bond linker enables ‘click’ attachment of peptides to oligonucleotides on solid support

A general procedure, based on a new activated alkyne linker, for the preparation of peptide–oligonucleotide conjugates (POCs) on solid support has been developed. With this linker, conjugation is effective at room temperature (RT) in millimolar concentration and submicromolar amounts. This is made possible since the use of a readily attachable activated triple bond linker enhances the Cu(I) catalyzed 1,3-dipolar cycloaddition (‘click’ reaction). The preferred scheme for conjugate preparation involves sequential conjugation to oligonucleotides on solid support of (i) an H-phosphonate-based aminolinker; (ii) the triple bond donor p-(N-propynoylamino)toluic acid (PATA); and (iii) azido-functionalized peptides. The method gives conversion of oligonucleotide to the POC on solid support, and only involves a single purification step after complete assembly. The synthesis is flexible and can be carried out without the need for specific automated synthesizers since it has been designed to utilize commercially available oligonucleotide and peptide derivatives on solid support or in solution. Methodology for the ready conversion of peptides into ‘clickable’ azidopeptides with the possibility of selecting either N-terminus or C-terminus connection also adds to the flexibility and usability of the method. Examples of synthesis of POCs include conjugates of oligonucleotides with peptides known to be membrane penetrating and nuclear localization signals.
Network Inference from Grouped Data

In medical research, economics, and the social sciences data frequently appear as subsets of a set of objects. Over the past century a number of descriptive statistics have been developed to construct network structure from such data. However, these measures lack a generating mechanism that links the inferred network structure to the observed groups. To address this issue, we propose a model-based approach called the Hub Model which assumes that every observed group has a leader and that the leader has brought together the other members of the group. The performance of Hub Models is demonstrated by simulation studies. We apply this model to infer the relationships among Senators serving in the 110th United States Congress, the characters in a famous 18th century Chinese novel, and the distribution of flora in North America.
Image reconstruction and correction methods in neutron and X-ray tomography

Neutron and X-ray tomography are imaging techniques for getting information about the interior of objects in a non-destructive way. They reconstruct cross-sections from projection images of the object being investigated. Due to the properties of the image acquisition system, the projection images are distorted by several artifacts, and these reduce the quality of the reconstruction. In order to eliminate these harmful effects the projection images should be corrected before reconstruction. Taking projections is usually an expensive and time consuming procedure. One of our main goals has been to try to minimize the number of projections - for example, by exploiting more a priori information. A possible way of reducing the number of projections is by the application of discrete tomographic methods. In this case a special class of objects can be reconstructed, consisting of only a few homogenous materials that can be characterized by known discrete absorption values. To this end we have implemented two reconstruction methods. One is able to reconstruct objects consisting of cylinders and spheres made of homogeneous materials only. The other method is a general one in the sense that it can be used for reconstructing any shape. Simulations on phantoms and physical measurements were carried out and the results are presented here.
Ranking fMRI Time Courses by Minimum Spanning Trees: Assessing Coactivation in fMRI

In fMRI, time courses with similar temporal "activation" patterns may belong to different brain regions (i.e., these regions are functionally connected, coactivated). A group of time courses (TCs) corresponding to a particular type of temporal activation pattern should be maximally self-consistent (homogeneous). We demonstrate that ordering a group of multidimensional fMRI time courses by a minimum spanning tree (MST) may be used to investigate the temporal homogeneity of a group of TCs. We show the utility of MST ranking for data-driven analysis methods in investigating coactivation in fMRI. MST ranking is equally useful for hypothesis-led methods. Furthermore, MST ranking enables pairwise comparisons of groups/clusters (i.e., any collection of TCs, no matter how derived) of fMRI time courses.
Power4 System Design for High Reliability

The Power4 is an integrated system on a chip (SoC) designed for systems that will initially target enterprise Unix customers and, at a later date, O/S 400 customers. Power4 systems are servers comprised of several Power4 chips. To achieve reliability goals, Power4 system design incorporates fault tolerance throughout the hardware, firmware and operating system. Together, these system components provide concurrent and deferred maintenance, multi-level recovery from errors and run-time diagnostics.
A Computer Vision Based Prototype for Automatic Guitarist Fingering Retrieval

This article presents a method to visually detect and recognize ﬁngering gestures of the left hand of a guitarist. The choice of computer vision to perform that task is motivated by the absence of a satisfying method for realtime guitarist ﬁngering detection. The development of this computer vision method follows preliminary manual and automated analyses of video recordings of a guitarist. These ﬁrst analyses led to some important ﬁndings about the design methodology of such a system, namely the focus on the eﬀective gesture, the consideration of the action of each individual ﬁnger, and a recognition system not relying on comparison against a knowledge-base of previously learned ﬁngering positions. Motivated by these results, studies on three important aspects of a complete ﬁngering system were conducted. One study was on re-altime ﬁnger-localization, another on string and fret detection, and the last on movement segmentation. Finally, these concepts were integrated into a prototype and a system for left-hand ﬁngering detection was developed. Such a data acquisition system for ﬁngering retrieval has uses in music theory, music education, automatic music and accompaniment generation and physical modeling.
Erim Report Series Research in Management Interest and Hazard Rates of Russian Saving Banks Bibliographic Data and Classifications

The number of (registered) commercial banks in Russia increased at a fast pace after the 1988 banking reform. Many of these banks lacked supervision and operated with dangerously low funding capital. In this paper we investigate the determinants of the hazard rates of banks active on the Moscovian deposits market during the 1994-97 period. We find that market share and duration have had a negative effect on the hazard rate, while the interest rate offered has had a positive effect.
Improving health services to displaced persons in Aceh, Indonesia: a balanced scorecard.

PROBLEM After the Indian Ocean tsunami in December 2004, the International Organization for Migration constructed temporary health clinics to provide medical services to survivors living in temporary accommodation centres throughout Aceh, Indonesia. Limited resources, inadequate supervision, staff turnover and lack of a health information system made it challenging to provide quality primary health services. APPROACH A balanced scorecard was developed and implemented in collaboration with local health clinic staff and district health officials. Performance targets were identified. Staff collected data from clinics and accommodation centres to develop 30 simple performance measures. These measures were monitored periodically and discussed at meetings with stakeholders to guide the development of health interventions. LOCAL SETTING Two years after the tsunami, 34 000 displaced persons continued to receive services from temporary health clinics in two districts of Aceh province. From March to December 2007, the scorecard was implemented in seven temporary health clinics. RELEVANT CHANGES Interventions stimulated and tracked by the scorecard showed measurable improvements in preventive medicine, child health, capacity building of clinic staff and availability of essential drugs. By enhancing communication, the scorecard also led to qualitative benefits. LESSONS LEARNT The balanced scorecard is a practical tool to focus attention and resources to facilitate improvement in disaster rehabilitation settings where health information infrastructure is poor. Introducing a mechanism for rapid improvement fostered communication between nongovernmental organizations, district health officials, clinic health workers and displaced persons.
Watermill: An Optimized Fingerprinting System for Databases under Constraints

This paper presents a walermarking/fingerprinting system for relational databases. It features a built-in declarative language to specify usability constraints that watermarked data sets must comply with. For a subset of these constraints, namely, weight-independent constraints, we propose a novel watermarking strategy that consists of translating them into an integer linear program. We show two watermarking strategies: an exhaustive one based on integer linear programming constraint solving and a scalable pairing heuristic. Fingerprinting applications, for which several distinct watermarks need to be computed, benefit from the reduced computation time of our method that precomputes the watermarks only once. Moreover, we show that our method enables practical collusion-secure fingerprinting since the precomputed watermarks are based on binary alterations located at exactly the same positions. The paper includes an in-depth analysis of false-hit and false-miss occurrence probabilities for the detection algorithm. Experiments performed on our open source software WATERMILL assess the watermark robustness against common attacks and show that our method outperforms the existing ones concerning the watermark embedding speed.
Astrocyte Aquaporin Dynamics in Health and Disease

The family of aquaporins (AQPs), membrane water channels, consists of diverse types of proteins that are mainly permeable to water; some are also permeable to small solutes, such as glycerol and urea. They have been identified in a wide range of organisms, from microbes to vertebrates and plants, and are expressed in various tissues. Here, we focus on AQP types and their isoforms in astrocytes, a major glial cell type in the central nervous system (CNS). Astrocytes have anatomical contact with the microvasculature, pia, and neurons. Of the many roles that astrocytes have in the CNS, they are key in maintaining water homeostasis. The processes involved in this regulation have been investigated intensively, in particular regulation of the permeability and expression patterns of different AQP types in astrocytes. Three aquaporin types have been described in astrocytes: aquaporins AQP1 and AQP4 and aquaglyceroporin AQP9. The aim here is to review their isoforms, subcellular localization, permeability regulation, and expression patterns in the CNS. In the human CNS, AQP4 is expressed in normal physiological and pathological conditions, but astrocytic expression of AQP1 and AQP9 is mainly associated with a pathological state.