Miracle-dz/UniFAR-FTUs huggingface dataset:
Combination of face classifiers for person identification

In this paper we present a system for person identification which is based on the combination of several face classifiers. First, we describe briefly the individual face classifiers. The classifier combination is then discussed. Finally, the impact of the combination is presented in a series of practical experiments which show a significant improvement of the recognition rate.
Numerical analysis of modulated metasurface antennas using Fourier-Bessel basis functions

Metasurfaces are thin (2D) metamaterials designed for manipulating the dispersion properties of surface-waves (SWs) or the reflection properties of incident plane-waves. Thanks to the sub-wavelength sizes of the patches used in the implementation step, these surfaces can be described by a surface impedance boundary condition (IBC). In this paper, we investigate a “Method of Moments” (MoM) based analysis of such surface with a family of entire-domain basis functions named “Fourier-Bessel” functions. The orthogonality property of these functions on a disk allows us to represent any smooth current distribution in an effective manner and thereby to drastically reduce the size of the MoM matrix.
Neural and endocrine circuits mediating inhibition of bradykinin-induced plasma extravasation by subcutaneous and spinal-intrathecal nicotine.

In this study we evaluated the mechanisms underlying s.c. and spinal intrathecal (i.t.) nicotine inhibition of bradykinin-induced plasma extravasation in the knee joint of the rat (J. Pharmacol. Exp. Ther. 262: 889-895, 1992; ibid., 264: 839-844, 1993). The dose-response curve for the inhibitory action of s.c. nicotine on bradykinin-induced plasma extravasation was attenuated by adrenal medullectomy and by intra-articular perfusion of ICI-118,551 (a beta-2 adrenoceptor antagonist). In addition, the dose-response curve of s.c. nicotine was attenuated by acute surgical lumbar sympathectomy and by intra-articular phentolamine (an alpha adrenoceptor antagonist). The dose-response curve for i.t. nicotine (up to 1 mg/kg) was not attenuated by intra-articular ICI-118,551 and was potentiated by adrenal medullectomy. The action of i.t. nicotine was also not affected by intra-articular phentolamine or by acute surgical lumbar sympathectomy. These results suggest that the inhibition of bradykinin-induced plasma extravasation in the knee joint of the rat by s.c. , but not i.t. , nicotine is mediated through the sympathoadrenal and sympathetic systems.
Propagation Analysis of Circular Surface Waveguides with a Periodically Corrugated Ground Plane

SUMMARY A mode-matching technique in conjunction with the Floquet theorem is proposed to analyze the propagation characteristics of periodic circular surface waveguides. The circular waveguides are coated outside with a multilayered dielectric and have a ground plane with periodic corrugation of arbitrary profile. Three different ground corrugation profiles are examined to demonstrate the influences of the corrugation shape, depth, and width, dielectric thickness, and relative permittivity on bandstop characteristics.
Infliximab for the treatment of fistulas in patients with Crohn's disease.

BACKGROUND Enterocutaneous fistulas are a serious complication of Crohn's disease and are difficult to treat. Infliximab, a chimeric monoclonal antibody to tumor necrosis factor alpha, has recently been developed as a treatment for Crohn's disease. We conducted a randomized, multicenter, double-blind, placebo-controlled trial of infliximab for the treatment of fistulas in patients with Crohn's disease. METHODS The study included 94 adult patients who had draining abdominal or perianal fistulas of at least three months' duration as a complication of Crohn's disease. Patients were randomly assigned to receive one of three treatments: placebo (31 patients), 5 mg of infliximab per kilogram of body weight (31 patients), or 10 mg of infliximab per kilogram (32 patients); all three were to be administered intravenously at weeks 0, 2, and 6. The primary end point was a reduction of 50 percent or more from base line in the number of draining fistulas observed at two or more consecutive study visits. A secondary end point was the closure of all fistulas. RESULTS Sixty-eight percent of the patients who received 5 mg of infliximab per kilogram and 56 percent of those who received 10 mg per kilogram achieved the primary end point, as compared with 26 percent of the patients in the placebo group (P=0.002 and P=0.02, respectively). In addition, 55 percent of the patients assigned to receive 5 mg of infliximab per kilogram and 38 percent of those assigned to 10 mg per kilogram had closure of all fistulas, as compared with 13 percent of the patients assigned to placebo (P=0.001 and P=0.04, respectively). The median length of time during which the fistulas remained closed was three months. More than 60 percent of patients in all the groups had adverse events. For patients treated with infliximab, the most common were headache, abscess, upper respiratory tract infection, and fatigue. CONCLUSIONS Infliximab is an efficacious treatment for fistulas in patients with Crohn's disease.
Effects of computerized guidelines for managing heart disease in primary care

BACKGROUND: Electronic information systems have been proposed as one means to reduce medical errors of commission (doing the wrong thing) and omission (not providing indicated care). OBJECTIVE: To assess the effects of computer-based cardiac care suggestions.DESIGN: A randomized, controlled trial targeting primary care physicians and pharmacists.SUBJECTS: A total of 706 outpatients with heart failure and/or ischemic heart disease.INTERVENTIONS: Evidence-based cardiac care suggestions, approved by a panel of local cardiologists and general internists, were displayed to physicians and pharmacists as they cared for enrolled patients.MEASUREMENTS: Adherence with the care suggestions, generic and condition-specific quality of life, acute exacerbations of their cardiac disease, medication compliance, health care costs, satisfaction with care, and physicians’ attitudes toward guidelines.RESULTS: Subjects were followed for 1 year during which they made 3,419 primary care visits and were eligible for 2,609 separate cardiac care suggestions. The intervention had no effect on physicians’ adherence to the care suggestions (23% for intervention patients vs 22% for controls). There were no intervention-control differences in quality of life, medication compliance, health care utilization, costs, or satisfaction with care. Physicians viewed guidelines as providing helpful information but constraining their practice and not helpful in making decisions for individual patients.CONCLUSIONS: Care suggestions generated by a sophisticated electronic medical record system failed to improve adherence to accepted practice guidelines or outcomes for patients with heart disease. Future studies must weigh the benefits and costs of different (and perhaps more Draconian) methods of affecting clinician behavior.
Real-Time Image-Based Lighting of Dynamic Scenes with Moment Soft Shadow Mapping

Casting shadows in dynamic scenes under complex illumination is a challenging problem, since no precomputation can be applied. The illumination is provided in form of a light probe, which potentially changes every frame. We propose a method for generating area lights from the light probe, built upon a median cut algorithm for light probe sampling. The shadows from the area lights are efficiently computed by moment soft shadow mapping, which has a lower memory footprint than other techniques. In this process very large area lights are utilized, pushing the limits of moment soft shadow mapping. We demonstrate the use of 6 instead of 4 moments in moment soft shadow mapping, which drastically increases the quality of the shadows for large area lights. We also present some other modifications, in order to improve the resulting shadows. We implemented the algorithm for generating area lights in compute shaders and demonstrate the sampling of animated light probes on the GPU and lighting of a dynamic scene in real time.
Species‐ and gender‐dependent differences in the glucuronidation of a flavonoid glucoside and its aglycone determined using expressed UGT enzymes and microsomes

Flavonoids occur naturally as glucosides and aglycones. Their common phenolic hydroxyl groups may trigger extensive UDP‐glucuronosyltransferase (UGT)‐ catalysed metabolism. Unlike aglycones, glucosides contain glucose moieties. However, the influence of these glucose moieties on glucuronidation of glucosides and aglycones remains unclear. In this study, the flavonoid glucoside tilianin and its aglycone acacetin were used as model compounds. The glucuronidation characteristics and enzyme kinetics of tilianin and acacetin were compared using human UGT isoforms, liver microsomes and intestinal microsomes obtained from different animal species. Tilianin and acacetin were metabolized into different glucuronides, with UGT1A8 produced as the main isoform. Assessment of enzyme kinetics in UGT1A8, human liver microsomes and human intestinal microsomes revealed that compared with tilianin, acacetin displayed lower Km (0.6‐, 0.7‐ and 0.6‐fold, respectively), higher Vmax (20‐, 60‐ and 230‐fold, respectively) and higher clearance (30‐, 80‐ and 300‐fold, respectively). Furthermore, glucuronidation of acacetin and tilianin showed significant species‐ and gender‐dependent differences. In conclusion, glucuronidation of flavonoid aglycones is faster than that of glucosides in the intestine and the liver. Understanding the metabolism and species‐ and gender‐dependent differences between glucosides and aglycones is crucial for the development of drugs from flavonoids. Copyright © 2015 John Wiley & Sons, Ltd.
Follow-up of heroin addicts in Spain (EMETYST project): results 1 year after treatment admission.

Summary The EMETYST (Estudio Multicentrico de Evaluacion de Tratamientos y Seguimiento de Toxicomanos) project describes demographic characteristics and history of drug abuse in a sample of 311 heroin addicts, who began treatment for addiction between the months of March and July 1985 in 16 different outpatient drug-free clinics in Spain. The outcome of these patients was studied prospectively at 6 and 12 months after the onset of treatment. Drug use, psychological status, occupational status, and legal status were the main areas of interest. At 12 months, 51% of patients had discontinued heroin use (p < 0.01). Ten per cent of patients remained on treatment for 1 year of more. As previously reported in other studies, treatment decreased heroin use and improved psychological status. Predictive factors of the patient's status at 12 months were duration of therapy, pretreatment criminal history, and results obtained at 6-month follow-up.
Circulation of HIV‐1 subtype A within the subtype C HIV‐1 epidemic in Tamil Nadu, India

The HIV‐1 epidemic in India is caused mainly by subtype C viruses that are transmitted sexually and by injecting drug use. The state of Tamil Nadu in Southern India has an HIV‐1 median prevalence of 16.8% among injecting drug users, 6.6% in men who have sex with men, and 4.6% in female sex workers. In the rural district of Namakkal, a prevalence >3% was detected among antenatal women. The goal of this study was to determine the HIV‐1 molecular epidemiology in Tamil Nadu. Blood samples were collected from 40 high‐risk HIV‐seropositive individuals from Chennai and Namakkal. HIV‐1 subtype was determined by envelope nucleotide sequencing. Among the samples studied, 85% were subtype C, however, a cluster of subtype A samples (12.5%) and one subtype E recombinant form CRF01_AE (close to the Thailand strains) were detected. The average genetic distance of subtype C samples from Chennai and Namakkal were 9.44 ± 0.77% and 11.8 ± 0.7%, respectively indicating an evolved epidemic. This pilot study confirmed that subtype C was predominant in these regions but an outbreak of subtype A was detected in Namakkal. These results stress the importance of periodic monitoring of circulating HIV‐1 subtypes in South India. J. Med. Virol. 84:1507–1513, 2012. © 2012 Wiley Periodicals, Inc.
The Furuta's pendulum stabilization without the use of a mathematical model: Attractive Ellipsoid Method with KL-adaptation

This paper presents a development of adaptive state estimator and output controller based on Attractive Ellipsoid Method (AEM) for the stabilization of the Furuta's pendulum. The proposed method guaranties that the controlled system trajectories are stabilized within an ellipsoid of a “minimal size”. We expand the classical AEM without adaptation to a class of observer and controller compensator with time varying gain matrices K and L adjusted on-line by specific adaptation procedure, that guaranties the convergence of the trajectories to an ellipsoid of less size compared to one without adaptation. In the case of the considered pendulum the incorporated adaptation procedures provides a stabilization in the vertical position practically with negligible vibrations, or in other words, without any “chattering effect”.
Analysis on Shape Image Retrieval Using DNN and ELM Classifiers for MRI Brain Tumor Images

The problem of searching a digital image in a very huge database is called Content Based Image Retrieval (CBIR). Shape is a significant cue for describing objects. In this paper, we have developed a shape feature extraction of MRI brain tumor image retrieval. We used T1 weighted image of MRI brain tumor images. There are two modules: feature extraction process and classification. First, the shape features are extracted using techniques like Scale invariant feature transform (SIFT), Harris corner detection and Zernike Moments. Second, the supervised learning algorithms like Deep neural network (DNN) and Extreme learning machine (ELM) are used to classify the brain tumor images. Experiments are performed using 1000 brain tumor images. In the performance evaluation, sensitivity, specificity, accuracy, error rate and f-measure are five measures are used. The Experiment result shows that highest average accuracy has got at Zernike Moments- 99%. So, Zernike Moments are better than SIFT and Harris corner detection techniques. The average time taken for DNN- 0.0901 sec, ELM- 0.0218 sec. So, ELM classifier is better than DNN. It increases the retrieval time and improves the retrieval accuracy significantly.
An approach for aspect-oriented skeleton code generation from reusable aspect models

Model-driven code generation has been a topic of interest for researchers owing to its several benefits including the anticipated reduction in development effort and delivery time. It has taken a good deal of time to produce techniques that generate executable code in object-oriented programming languages. Aspect-oriented software development techniques, though expected to enhance software development in many ways, still lack approaches that can deliver model-driven code into one of the aspect-oriented programming languages such as AspectJ. In this paper, we present an approach for generation of aspect-oriented code from Reusable Aspect Models. As first step towards the code generation, we have developed a formal and semantically equivalent text-based representation of the aspect models using XML schema notation. Further, we have proposed an approach that takes the XML representation of the aspect models to generate aspect-oriented skeleton code. Currently, our approach can be used to obtain complete aspect structure, interfaces, classes, constructors, fields and stubs of methods specified in the structural part of an aspect
A comparison study between static and dynamic recurrent neural networks based adaptive control of nonlinear multivariable systems

This paper considers the problem of real time adaptive control of nonlinear multivariable systems. Two neural networks techniques are presented to solve the problem mentioned above. The first technique combines the ability of a single-layer feedforward neural network for modeling purposes and a linear control law to design the controller. The second technique combines the ability of dynamic recurrent neural network for modeling purposes and a linear control law to design the controller. In this paper, we consider that the state of the system is accessible. A comparison between the simulation results for the above two techniques are presented to complete the study.
To transmit or not to transmit: an investigation using competitive analysis

In this paper, we present solutions to minimize wastage of battery power and bandwidth through the design of efficient transmission control strategies. We present several on-line transmission techniques. We analyze the proposed algorithms using competitive analysis techniques against an optimal off-line strategy, which has perfect knowledge of the channel conditions in future. We show that all of our techniques are highly competitive with a majority of them having a small constant-factor (at most 2) competitive ratio.
Why Evaluate Ontology Technologies? Because It Works!

We deal with two types of ontology evaluation, content evaluation and ontology technology evaluation. Evaluating content is a must for preventing applications from using inconsistent, incorrect, or redundant ontologies. It's unwise to publish an ontology that one or more software applications will use without first evaluating it. A well-evaluated ontology won't guarantee the absence of problems, but it makes its use safer. Similarly, evaluating ontology technology eases its integration with other software environments, ensuring a correct technology transfer from the academic to the industrial world. We also discuss ontology libraries, ontology tool, and formal evaluation of ontology quality.
Classification of Frequent Subgraph Mining Algorithm For Various Graph Data-Survey

Graphs are one of the complex data modeling techniques which are usually represented in the form of edges and vertices. Frequent Subgraph mining is one of the tasks for identifying frequent subgraphs. With the help of Frequent Subgraphs, operations like searching, classifying, characterizing and indexing is performed effectively in graph databases. The methods which are used for identify the frequent subgraphs in all real time databases are varied because of the diversity of graph data. In this paper, we described that the algorithms which is more suitable for the different kinds of graph data by comparing with various algorithms.
Immunobiology of Toll‐like receptors: Emerging trends

Toll‐like receptors (TLR), a family of evolutionarily conserved pathogen recognition receptors, play pivotal role as primary sensors of invading pathogens. TLR identify molecular motifs of infectious agents (pathogen associated molecular patterns) and elicit an effective defensive response against them. Mammalian TLR derive their name from the Drosophila Toll protein, with which they share sequence similarity. So far, expression of 10 TLR is known in humans. The adaptor proteins, myeloid differentiation factor 88 and Toll IL‐1 receptor (TIR) domain containing adaptor inducing IFN‐β (TRIF) are the key players in the TLR signalling cascade leading to the activation of nuclear factor (NF)‐κB and interferon regulatory factor‐3, respectively. Targeted manipulation of the TLR signalling pathway has immense therapeutic potential and may eventually prove to be a boon in the development of innovative treatments for diverse disease conditions. There is accumulating evidence that TLR agonists have tremendous potential as novel therapeutic targets. In this review, we have discussed the immunobiology of TLR and emphasize significant advances made within the ever‐expanding field of TLR that provide intriguing insights efficacious in unravelling the complexities associated with TLR.
Psychopathology of eating disorders: a controlled comparison of bulimic, obese, and normal subjects.

Utilisant le MMPI, le SCL-90, le BDI et une evaluation de l'image du corps, les auteurs ont trouve une psychopathologie significativement plus importante chez les boulimiques (N=15) par rapport a des sujets normaux (N=15), et a des sujets obeses (N=15): plus anxieux, depressifs, nevrotiques et impulsifs
First detection and molecular characterization of Nebovirus in Brazil

SUMMARY Nebovirus is a new genus of viruses belonging to the Caliciviridae family recently characterized in cattle, and is associated with gastrointestinal disorders, such as diarrhoea, anorexia and intestinal lesions particularly in calves. The aim of this study was to investigate the prevalence of neboviruses in Brazilian cattle and analyse phylogenetically the virus strains detected. A prevalence of 4·8% of neboviruses in faecal samples from 62 head of cattle from different Brazilian states was detected. All positive animals were aged <20 days and had diarrhoea. Phylogenetic analysis clustered the virus sequences into the Newbury1 clade. There was >96·0% nt (100% aa) sequence identity between the virus sequences in this study and >88·8% nt (>94·4% aa) identity with Newbury1/UK. Our results indicate, for the first time, the occurrence of neboviruses in Brazil as well as in South America, and the first Newbury1-like nebovirus found outside the UK.
Modulation by muscarinic antagonists of the response to carbon dioxide challenge in panic disorder.

BACKGROUND Panic attacks can be induced in persons with panic disorder by inhalation of carbon dioxide. Hypercapnia also elicits a reflex hyperventilation, which is controlled in part by cholinergic mechanisms. This study investigated whether the exaggerated response to carbon dioxide in panic disorder (PD) can be modulated by antagonists of muscarinic cholinergic receptors. METHODS Twelve patients with PD received biperiden hydrochloride (a muscarinic antagonist that crosses the blood-brain barrier), pirenzepine hydrochloride (a muscarinic antagonist that does not cross the blood-brain barrier), or placebo 2 hours before a 35% carbon dioxide-65% oxygen respiratory challenge (vs air as a placebo) on 3 separate days, in a double-blind, random crossover design. RESULTS According to patients' self-ratings of subjective anxiety, inhalation of the carbon dioxide/oxygen mixture provoked a significant and intense response after treatment with pirenzepine and placebo. After biperiden treatment, however, hypercapnia elicited a response profile similar to that elicited by air, whereby subjective anxiety remained similar to preinhalation levels. CONCLUSIONS Consistent with the hypothesis of the study, a centrally active muscarinic antagonist can block the response to carbon dioxide commonly observed in subjects with PD.