Miracle-dz/UniFAR-FTUs huggingface dataset:
Terrestrial mobile communication train measurements in western India

Mobile train radio measurements were conducted in the UHF band in western India with a total distance of 140 km utilizing eight track side base stations in different environments. The observed path losses deduced from signal levels were compared with those deduced from several prediction methods and their standard deviations are discussed. Path loss exponents are derived from signal levels and their variation as a function of distance are also presented. Suitable prediction methods for this region are identified. These studies would be useful for designing future train mobile communication systems in this region, for spectrum management applications and in framing recommendations for the radio communication study group of ITU-R.
Wisconsin Card Sorting Task (WCST) errors and cerebral blood flow in obsessive-compulsive disorder (OCD).

We compared Wisconsin Card Sorting Task (WCST) performance in 19 obsessive-compulsive disorder (OCD) patients and 19 individually matched healthy controls. Measures of intelligence and mood were taken into account for all participants. Within the patient group, factors such as duration and severity of symptoms (as assessed using the Yale-Brown Obsessive-Compulsive Scale, Y-BOCS) were considered. We explored the relationship between OCD WCST errors and regional cerebral blood flow (rCBF) on brain dedicated, high resolution, single photon emission tomography (SPET). We used uptake of 99mTc-hexamethylpropylamine oxime (HMPAO) on SPET to estimate rCBF, and regional values were quantified as ratios of cerebellar blood flow. WCST results confirmed OCD patients were significantly impared when compared with age- and sex-matched healthy volunteers. Patients made significantly more trials, more preseverative errors, and more null-sorts. OCD patients Y-BOCS 'obsessive' subtotal significantly correlated with many WCST errors. Furthermore OCD WCST null-sorts correlated significantly with SPET OCD left inferior frontal cortical rCBF (r(18) = . 47, p = . 05) and left caudate rCBF (r(18) = . 72, p = . 01). The implications of these findings are discussed in the context of other studies which examine functional imaging and neuropsychology in OCD.
Rosanilins: indicator dyes for chloramphenicol-resistant enterobacteria containing chloramphenicol acetyltransferase

Rosanilin dyes such as crystal violet and basic fuchsin have been used as indicator dyes in solid growth medium for chloramphenicol-resistant enterobacterial colonies containing the enterobacterial resistance enzyme chloramphenicol acetyltransferase (CAT). On certain media containing rosanilins, cells containing CAT formed darker colonies than cells not containing CAT. Contrast was affected by the types and concentrations of complex nutrients, sugars salts, and rosanilin dyes present. When crystal violet was used as the indicator dye, contrast could not be obtained for strains whose growth was partially inhibited by crystal violet. Contrast could not be obtained between yeast colonies with and without the enterobacterial resistance enzyme, between Bacillus subtilis colonies with and without the staphylococcal resistance enzyme, or between enterobacterial colonies with and without the staphylococcal resistance enzyme. The darker coloration of enterobacterial colonies with the enterobacterial enzyme was due to the binding of dye to enzyme. Rosanilin dues have been used to score resistance phenotypes by colony color, to detect chloramphenicol-sensitive sectors in chloramphenicol-resistant colonies, and to screen for occasional chloramphenicol-sensitive cells in a resistant population during cloning by insertional inactivation of the chloramphenicol resistance gene.
Conceptualization of science using collaboration and competences

The purpose of this paper is to propose an approach for conceptualizing science based on collaboration and competences of researchers. ,The research is conducted by exploratory analysis of collaboration and competences using case studies from humanistic, engineering, natural sciences and a general topic. ,The findings show that by applying the proposed approach on bibliographic data that readily exist for many national sciences as well as for international scientific communities, one can obtain useful new insights into the research. The approach is demonstrated with the following exploratory findings: identification of important connections and individual researchers that connect the community of anthropologists; collaboration of technical scientists in the community of anthropologists caused by an interdisciplinary research project; connectivity, interdisciplinary and structure of artificial intelligence, nanotechnology and a community based on a general topic; and identifying research interest shift described with concretization and topic-shift. ,As demonstrated with the practical implementation (http://scienceatlas.ijs.si/), users can obtain information of the most relevant competences of a researcher and his most important collaborators. It is possible to obtaining researchers, community structure and competences of an arbitrary research topic. ,The map for collaboration and competences of a complete science can be a crucial tool for policy-making. Social scientists can use the results of the proposed approach to better understand and direct the development of science. ,Originality and value of the paper is in combining text (competences) and network (research collaboration and co-authoring) approaches for exploring science. Additional values give the results of analysis that demonstrate the approach.
Assessing Capacity for Providing Culturally Competent Services to LGBT Older Adults

This qualitative, interview-based study assessed the cultural competence of health and social service providers to meet the needs of LGBT older adults in an urban neighborhood in Denver, Colorado, known to have a large LGBT community. Only 4 of the agencies were categorized as “high competency”; 12 were felt to be “seeking improvement” and 8 were considered “not aware. ” These results indicate significant gaps in cultural competency for the majority of service providers. Social workers are well-suited to lead efforts directed at improving service provision and care competencies for the older LGBT community.
On Path-Lifting Mechanisms and Unwinding in Quaternion-Based Attitude Control

The unit quaternion is a pervasive representation of rigid-body attitude used for the design and analysis of feedback control laws. Because the space of unit quaternions constitutes a double cover of the rigid-body-attitude space, quaternion-based control laws are often—by design—inconsistent, i.e., they do not have a unique value for each rigid-body attitude. Inconsistent quaternion-based control laws require an additional mechanism that uniquely converts an attitude estimate into its quaternion representation; however, conversion mechanisms that are memoryless—e.g., selecting the quaternion having positive scalar component—have a limited domain where they remain injective and, when used globally, introduce discontinuities into the closed-loop system. We show—through an explicit construction and Lyapunov analysis—that such discontinuities can be hijacked by arbitrarily small measurement disturbances to stabilize attitudes far from the desired attitude. To remedy this limitation, we propose a hybrid-dynamic algorithm for smoothly lifting an attitude path to the unit-quaternion space. We show that this hybrid-dynamic mechanism allows us to directly translate quaternion-based controllers and their asymptotic stability properties (obtained in the unit-quaternion space) to the actual rigid-body-attitude space. We also show that when quaternion-based controllers are not designed to account for the double covering of the rigid-body-attitude space by a unit-quaternion parameterization, they can give rise to the unwinding phenomenon, which we characterize in terms of the projection of asymptotically stable sets. Finally, we employ the main results to show that certain hybrid feedbacks can globally asymptotically stabilize the attitude of a rigid body.
Extremely low genetic variability and highly structured local populations of Arabidopsis thaliana at higher latitudes

The genetic diversity and population structure of Arabidopsis thaliana populations from Norway were studied and compared to a worldwide sample of A. thaliana to investigate the demographic history and elucidate possible colonization routes of populations at the northernmost species limit. We genotyped 282 individuals from 31 local populations using 149 single nucleotide polymorphism markers. A high level of population subdivision (FST = 0.85 ± 0.007) was found indicating that A. thaliana is highly structured at the regional level. Significant relationships between genetic and geographical distances were found, suggesting an isolation by distance mode of evolution. Genetic diversity was much lower, and the level of linkage disequilibrium was higher in populations from the north (65–68°N) compared to populations from the south (59–62°N); this is consistent with a northward expansion pattern. A neighbour‐joining tree showed that populations from northern Norway form a separate cluster, while the remaining populations are distributed over a few minor clusters. Minimal gene flow seems to have occurred between populations in different regions, especially between the geographically distant northern and southern populations. Our data suggest that northern populations represent a homogenous group that may have been established from a few founders during northward expansions, while populations in the central part of Norway constitute an admixed group established by founders of different origins, most probably as a result of human‐mediated gene flow. Moreover, Norwegian populations appeared to be homogenous and isolated compared to a worldwide sample of A. thaliana, but they are still grouped with Swedish populations, which may indicate common colonization histories.
Association of maternal, antenatal and perinatal complications with suicide in adolescence and young adulthood

The aim of the present study was to investigate whether maternal, antenatal and perinatal complications are associated with adolescent or young adulthood suicide in offspring. Cases consisted of individuals, aged 15–22 years, born in New York City and committing suicide in New York City between 1985 and 1991 (n= 189). Two controls were selected for each case, constituting the hospital birth immediately preceding and following that of the case, matched with the case with regard to sex and ethnicity. Cases were compared with controls using an index that summed a range of maternal, antenatal and perinatal complications and also with regard to the frequency of individual complications. In the total sample, cases and controls did not differ either in the mean number of all complications combined or in the proportions with specific complications. This lack of association between complications and outcome also obtained in separate analyses by sex, ethnicity, socio‐economic status and age at suicide. These results fail to replicate the findings of two previous reports implicating maternal, antenatal and perinatal complications in risk of youth suicide. At present, epidemiological evidence that adverse reproductive events increase the risk for suicide in offspring remains inconclusive.
FORMULATION AND EVALUATION OF BILAYER BUCCAL TABLET OF SUMATRIPTAN SUCCINATE

Objective: To develop mucoadhesive bilayer buccal tablet of sumatriptan succinate to enhance its bioavailability and reduce its dosing frequency. Method: A batch prepared with ratio of HPMC K15: HPMC K100LV as 1:3, 4% Penetration enhancer, 40mg backing layer, compressed at 2 tons/cm2 for 10 s was identified as an ideal batch based on its buccal residence time and optimum mucoadhesive strength of 13.99 g. The formulated tablets were stable with respect to their physicochemical and in vitro drug release behaviour over a period of 60 days at different temperatures and relative humidity. Results: The Optimised buccal tablet batch shows the drug release up to 90% in 8hr, good mucoadhesive time as 470 Min. Conclusion: Mucoadhesive bilayered buccal tablet of sumatriptan succinate may have enhanced bioavailability. A combination of polymer HPMC K15: HPMC K100LV in the ratio of 1:3 shows good mucoadhesive strength, ex-vivo drug release, and good mucoadhesive time.
On the Security of a Dynamic and Secure Key Management Model for Hierarchical Heterogeneous Sensor Networks

With the development of the wireless communication technology and the sensor technology, the wireless sensor network (WSN) has been used in many applications. However, WSNs suffer from some inherent weaknesses because of restricted communication and hardware capabilities. To achieve essentially secure communication in WSNs, a few of key management models have been proposed since it is the crucial important building block for all security goals in WSNs. Recently, Alagheband and Aref proposed a signcryption scheme and used it to construct a dynamic key management model for hierarchical heterogeneous sensor networks. They also proved that their signcryption scheme is provably secure if the elliptic curve discrete logarithm problem is infeasible. Unfortunately, by giving concrete attacks, we indicate that Alagheband and Aref’s signcryption scheme is not secure in their secure model. The analysis also shows that their key management model is not secure. To solve those weaknesses, we also proposed an improved signcryption scheme.
Las isoformas de endoglina en la señalización del TGF?1

El estudio de los procesos de senalizacion celular es uno de los campos de investigacion de mayor relevancia en la actualidad y que ha tenido una progresion espectacular en los ultimos veinte anos. Una de las vias de senalizacion mas estudiadas es la del factor de crecimiento transformante beta (TGFs). El interes suscitado por el conocimiento profundo de cada uno de los componentes implicados en esta via de senalizacion y su funcion, se debe a la importancia de encontrar alternativas terapeuticas que impidan el desarrollo de enfermedades muy graves en las que el TGFs tiene un papel muy importante, entre las que figuran las patologias fibroticas, angiogenesis, progresion tumoral, etc.
EMI Modeling in Automotive Data Communication Structure

Data links are facing more internal and external electromagnetic noises due to high speed data communications in the automobile industry. A mathematical model is presented to predict the EMI in automotive data link circuitries. This model is a useful mechanism that facilitates EMI reductions in the future automotive cable designs. Experimental results indicate that the model accurately predicts crosstalk-couplings of three 1.7 meter standard unshielded multi-conductor cables up to 80 MHz where the signal wavelength is at least two times longer than the cable length. All experimental data are collected inside a fully enclosed NoiseKen tent. The tent is in a shielded environment that minimizes background noises.
The Human HLA-A*0201 Allele, Expressed in Hamster Cells, Is Not a High-Affinity Receptor for Adenovirus Type 5 Fiber

ABSTRACT The coxsackie B virus and adenovirus receptor (CAR) and the major histocompatibility complex (MHC) class I α2 domain have been identified as high-affinity cell receptors for adenovirus type 5 (Ad5) fiber. In this study we show that CAR but not MHC class I allele HLA-A*0201 binds to Ad5 with high affinity when expressed on hamster cells. When both receptors are coexpressed on the cell surface of hamster cells, Ad5 fiber bind to a single high-affinity receptor, which is CAR.
Repeatability, reliability and reproducibility of posterior curvature and wavefront aberrations in keratoconic and cross‐linked corneas

The aim was to assess the intra‐session, inter‐session and inter‐observer repeatability of curvature and aberrometric measurements of Pentacam‐derived posterior corneal surface in normal control (CG), keratoconic (KCG) and after corneal collagen cross‐linked (CXLG) groups.
Physiopathology of Cushing's disease.

HARVEY CUSHING first described a patient with the disease bearing his name in 1912 (1). The patient manifested rapidly acquired central obesity, hypertrichosis, amenorrhea, and muscle weakness; on physical examination, “her round face was dusky and cyanoid,” supraclavicular and posterior cervical fat pads were present, and it was also noted that the skin was rough and dry, with considerable pigmentation, and with numerous ecchymoses and purplish striae. At that time, Cushing was uncertain as to whether the symptoms were attributable to pituitary “or adrenal, pineal, or ovarian influences,” involvement of these regions having previously been reported in association with similar clinical findings. There was apparently an even earlier report of a similar clinical syndrome by Osier in 1899 (2), which was described, however, as “An acute myxoedematous condition, with tachycardia, glycosuria, melaena, mania, and death” (the latter occurring within 6 months of onset). Between 1923 and 1926, in addition to other .
INVESTIGATION OF THE EXPLORE / EXPLOIT DILEMMA

To maximize reward, we are faced with the dilemma of having to balance the exploration of new response options and the exploitation of previous choices. Here, we sought to determine if the event-related brain potential (ERP) in the P300 time range is sensitive to decisions to explore or exploit within the context of a sequential risk-taking task. Specifically, the task we used required participants to continually explore their options—whether they should ‘‘push their luck’’ and keep gambling or ‘‘take the money and run’’ and collect their winnings. Our behavioral analysis yielded two distinct distributions of response times: a larger group of short-decision times and a smaller group of long-decision times. Interestingly, these data suggest that participants adopted one of two modes of control on any given trial: a mode where they quickly decided to keep gambling (i.e. exploit), and a mode where they deliberated whether to the take the money they had already won or continue gambling (i.e. explore). Importantly, we found that the amplitude of the ERP in the P300 time range was larger for explorative decisions than for exploitative decisions and, further, was correlated with decision time. Our results are consistent with a recent theoretical account that links changes in ERP amplitude in the P300 time range with phasic activity of the locus coeruleus–norepinephrine system and decisions to engage in exploratory behavior. 2012 IBRO. Published by Elsevier Ltd. All rights reserved.
Extracellular signal‐regulated kinase activation is required for consolidation and reconsolidation of memory at an early stage of ontogenesis

The ability to form long‐term memories exists very early during ontogeny; however, the properties of early memory processes, brain structures involved and underlying cellular mechanisms are poorly defined. Here, we examine the role of extracellular signal‐regulated kinase (ERK), a member of the mitogen‐activated protein kinase/ERK signaling cascade, which is crucial for adult memory, in the consolidation and reconsolidation of an early memory using a conditioned taste aversion paradigm in 3‐day‐old rat pups. We show that intraperitoneal injection of SL327, the upstream mitogen‐activated protein kinase kinase inhibitor, impairs both consolidation and reconsolidation of early memory, leaving short‐term memory after acquisition and after reactivation intact. The amnesic effect of SL327 diminishes with increasing delays after acquisition and reactivation. Biochemical analyses revealed ERK hyperphosphorylation in the amygdala but not the hippocampus following acquisition, suggesting functional activation of the amygdala as early as post‐natal day 3, although there was no clear evidence for amygdalar ERK activation after reactivation. These results indicate that, despite an immature brain, the basic properties of memory and at least some of the molecular mechanisms and brain structures implicated in aversion memory share a number of similarities with the adult and emerge very early during ontogeny.
Significantly improved analytical sensitivity of lateral flow immunoassays by using thermal contrast.

The ability to rapidly identify diseases enables prompt treatment and improves outcomes. This has increased the development and use of rapid point-of-care diagnostic devices capable of biomolecular detection in both high-income and resource-limited settings. [1] Lateral flow assays (LFAs) are inexpensive, simple, portable, and robust,[2] making LFAs commonplace in medicine, agriculture, and over-the-counter personal use such as for pregnancy testing. Although the analytical performance of some LFAs are comparable to laboratory based methods,[1a] the sensitivity of most LFAs is in the mM to μM range,[2–3] which is many folds less sensitive than other molecular techniques such as enzyme-linked immunoassays (ELISA). As a consequence, LFAs are not particularly useful for detection early in a disease course when there is low level of antigen. Due to the increasing need for highly sensitive molecular diagnostics, researchers have focused on developing microfluidics,[1a, 1b] biobar codes,[1c, 1d] and enzyme-based immunoassay technologies[4] technologies to fulfill the need since these technologies have nM to pM detection sensitivity for protein analysis and can potentially be miniaturized as handheld point-of-care diagnostic devices. [1c] These emerging technologies are still early in development and are not yet field-ready.
High-Resolution Physical Map of theSinorhizobium meliloti 1021 pSyma Megaplasmid

ABSTRACT To facilitate sequencing of the Sinorhizobium meliloti1021 pSyma megaplasmid, a high-resolution map was constructed by ordering 113 overlapping bacterial artificial chromosome clones with 192 markers. The 157 anonymous sequence tagged site markers (81,072 bases) reveal hypothetical functions encoded by the replicon.
Effects of Various Inotropic Interventions on the Dynamic Properties of the Contractile Elements in Heart Muscle of the Cat

Force-velocity-length (FVL) relations were obtained by determining the phase-plane tracings of velocity of shortening vs. length during isotonic contractions. These measurements were then replotted in a three-dimensional graph after correction for the series elastic extension during the isometric phase of the contractions as derived from a quick release contraction. On examining the influence of temperature (29° and 37°), preload, frequency of stimulation (12/min and 24−30/min), paired stimulation (PS), calcium (2.5 mM and 7.5 mM), and iso-proterenol (10-5M), it was shown that the surface created by the three-dimensional FVL relations of the contractile element (CE) is unique for a given state of contractility. Furthermore, the course of velocity vs. length is determined only by the instantaneous CE length, regardless of the contractile state of the CE, and is independent of the time after stimulation over a large portion of the shortening. From the intersection of the linear load-shortening relation observed for the CE with the load axis the maximum force (Po) development of the CE was derived. The highest values of this corrected Po (1.80 ± 0.13 kg/cm2) were seen following inotropic interventions such as PS, calcium, or isoproterenol. Using the corrected Po, truly hyperbolic force-velocity curves were constructed from which Vmax and the Hill equation constants a and b were derived for the various inotropic interventions.