Miracle-dz/UniFAR-FTUs huggingface dataset:
The Moderating Effects of Resident Characteristics on Perceived Gaming Impacts and Gaming Industry Support: The Case of Macao

ABSTRACT Based on a joint use of social exchange and social representation theories, this study examined the moderating effects of resident characteristics on the relationships between perceived gaming impacts, gaming benefits, and industry support. The findings demonstrated that the relationships changed when the resident characteristics (age, education, tourism industry dependence, and community attachment) were introduced to the structural model as moderators. The study provides a better understanding of which subgroup of people within a community are more or less disposed to certain impacts of gaming. The theoretical and practical implications were discussed.
A Survey of Adaptive and Real-Time Protocols Based on IEEE 802.15.4

The IEEE 802.15. 4 standard is a protocol that has been widely used in many applications exploiting wireless sensor networks (WSNs). However, it does not provide any means of differentiated services to improve the quality of service (QoS) for time-critical and delay-sensitive events. Furthermore, adaptive throughput performance for individual nodes cannot be supported with the current specifications. In this survey paper, we first discuss the negative aspects of IEEE 802.15. 4 MAC in contention access period, contention-free period, and the overall cross-period, respectively, in terms of adaptive and real-time guarantees. We then give an overview on some interesting mechanisms used in existing adaptive and real-time protocols in compliance with IEEE 802.15. 4. Careful examination of such research works reveals that by optimizing the original specifications and dynamically adjusting the protocol parameters, the total network efficiency can be significantly improved. Nevertheless, there are still certain challenges to overcome in pursuing the most appropriate protocol without introducing any unacceptable side effects.
Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524

The kinase Bub1 functions in the spindle assembly checkpoint (SAC) and in chromosome congression, but the role of its catalytic activity remains controversial. Here, we use two novel Bub1 inhibitors, BAY-320 and BAY-524, to demonstrate potent Bub1 kinase inhibition both in vitro and in intact cells. Then, we compared the cellular phenotypes of Bub1 kinase inhibition in HeLa and RPE1 cells with those of protein depletion, indicative of catalytic or scaffolding functions, respectively. Bub1 inhibition affected chromosome association of Shugoshin and the chromosomal passenger complex (CPC), without abolishing global Aurora B function. Consequently, inhibition of Bub1 kinase impaired chromosome arm resolution but exerted only minor effects on mitotic progression or SAC function. Importantly, BAY-320 and BAY-524 treatment sensitized cells to low doses of Paclitaxel, impairing both chromosome segregation and cell proliferation. These findings are relevant to our understanding of Bub1 kinase function and the prospects of targeting Bub1 for therapeutic applications. DOI: http://dx.doi. org/10.7554/eLife.12187. 001
Constrained target motion modeling — Part I: Straight line track

Straight line motion is one of the most fundamental target motions. Its modeling has been well studied for unconstrained targets, e.g., air targets. However, the existing straight line motion models can not be directly used for the constrained case on straight line tracks, which has wide application, e.g., in ground target tracking. In this paper, modeling of the constrained target motion on a straight line track is considered. First, the constraints imposed by the straight track are explicitly set up. Then both direct elimination and projection along-track are applied to obtain two forms of constrained motion models in the 2D Cartesian plane and 3D Cartesian space. The connections between these two forms are studied. It is found that the traditional linear Gaussian assumption is still valid for the nearly constant velocity models, the nearly constant acceleration models and the Singer model. Inspired by this, a general condition under which the traditional linear Gaussian assumption is valid for modeling of constrained motion on a straight track is also discussed.
Fungal and Prokaryotic Activities in the Marine Subsurface Biosphere at Peru Margin and Canterbury Basin Inferred from RNA-Based Analyses and Microscopy

The deep sedimentary biosphere, extending 100s of meters below the seafloor harbors unexpected diversity of Bacteria, Archaea, and microbial eukaryotes. Far less is known about microbial eukaryotes in subsurface habitats, albeit several studies have indicated that fungi dominate microbial eukaryotic communities and fungal molecular signatures (of both yeasts and filamentous forms) have been detected in samples as deep as 1740 mbsf. Here, we compare and contrast fungal ribosomal RNA gene signatures and whole community metatranscriptomes present in sediment core samples from 6 and 95 mbsf from Peru Margin site 1229A and from samples from 12 and 345 mbsf from Canterbury Basin site U1352. The metatranscriptome analyses reveal higher relative expression of amino acid and peptide transporters in the less nutrient rich Canterbury Basin sediments compared to the nutrient rich Peru Margin, and higher expression of motility genes in the Peru Margin samples. Higher expression of genes associated with metals transporters and antibiotic resistance and production was detected in Canterbury Basin sediments. A poly-A focused metatranscriptome produced for the Canterbury Basin sample from 345 mbsf provides further evidence for active fungal communities in the subsurface in the form of fungal-associated transcripts for metabolic and cellular processes, cell and membrane functions, and catalytic activities. Fungal communities at comparable depths at the two geographically separated locations appear dominated by distinct taxa. Differences in taxonomic composition and expression of genes associated with particular metabolic activities may be a function of sediment organic content as well as oceanic province. Microscopic analysis of Canterbury Basin sediment samples from 4 and 403 mbsf produced visualizations of septate fungal filaments, branching fungi, conidiogenesis, and spores. These images provide another important line of evidence supporting the occurrence and activity of fungi in the deep subseafloor biosphere.
Expert and competent non-expert visual cues during simulated diagnosis in intensive care

The aim of this study was to examine the information acquisition strategies of expert and competent non-expert intensive care physicians during two simulated diagnostic scenarios involving respiratory distress in an infant. Specifically, the information acquisition performance of six experts and 12 competent non-experts was examined using an eye-tracker during the initial 90 s of the assessment of the patient. The results indicated that, in comparison to competent non-experts, experts recorded longer mean fixations, irrespective of the scenario. When the dwell times were examined against specific areas of interest, the results revealed that competent non-experts recorded greater overall dwell times on the nurse, where experts recorded relatively greater dwell times on the head and face of the manikin. In the context of the scenarios, experts recorded differential dwell times, spending relatively more time on the head and face during the seizure scenario than during the coughing scenario. The differences evident between experts and competent non-experts were interpreted as evidence of the relative availability of task-specific cues or heuristics in memory that might direct the process of information acquisition amongst expert physicians. The implications are discussed for the training and assessment of diagnostic skills.
Making Ends Meet: Bringing Bilingual Education and Mainstream Students Together in Preservice Teacher Education

In some institutions offering certification for bilingual education and ESL teachers, the corresponding mainstream programs do little to ready their students to work effectively with language minority children. Yet today's mainstream classrooms are linguistically and culturally diverse, and all teachers must appreciate the role of language and culture in teaching and learning. This study describes one effort to consciously combine preservice bilingual and mainstream education teachers in a bilingual education methods cohort. Students reported promising gains in cross-cultural understanding and in cross-program appreciation. Some losses took place as well, however, and further innovation and research are needed in order to ensure that such efforts to combine programs strengthen, but not weaken, each program.
Continuity and Change in Indonesian Labour Relations in the Habibie Interregnum

There were considerable changes in Indonesia's industrial relations climate and regulatory framework during the Habibie interregnum. This article explores the implications of those changes for informal workers' organizations, unions and labour-oriented NGOs. The article is divided into two sections. The first section reflects upon the philosophy, institutions and practice of labour relations under Suharto's New Order and describes organized opposition to the industrial relations system, while the second describes the ways in which labour relations and representation changed during the Habibie interregnum.
A Quantum Query Expansion Approach for Session Search

Recently, Quantum Theory (QT) has been employed to advance the theory of Information Retrieval (IR). Various analogies between QT and IR have been established. Among them, a typical one is applying the idea of photon polarization in IR tasks, e.g., for document ranking and query expansion. In this paper, we aim to further extend this work by constructing a new superposed state of each document in the information need space, based on which we can incorporate the quantum interference idea in query expansion. We then apply the new quantum query expansion model to session search, which is a typical Web search task. Empirical evaluation on the large-scale Clueweb12 dataset has shown that the proposed model is effective in the session search tasks, demonstrating the potential of developing novel and effective IR models based on intuitions and formalisms of QT.
Depth Estimation based on Stereo Camera Pairs of Color and Infrared using Cross-based Local Multipoint Filter

This paper proposes a method of acquiring threedimensional shape data about moving objects based on stereo camera pairs of the color and the infrared by projecting infrared dot patterns. Most of the methods that project infrared pattern estimate a single depth map by measuring the translation of a known pattern with an infrared camera. The aim of the proposed method is to make 3D models by integrating depth maps from multiple viewpoints for 3D video production and 3D imaging. The method utilizes the infrared pattern as a texture and estimates depth maps by stereo matching of an infrared image pair and a color image pair. The matching cost is integrated by the weighted sum of the matching cost of the infrared image and the color image. Before the disparity candidate with the lowest cost is selected, cost volume filtering is applied to each cost map by using the cross-based local multipoint filter (CLMF). We present experimental results showing the effectiveness of our proposed and describe to apply it to three-dimensional integral imaging. Keywordsdepth estimation; stereo matching; cross-based local multipoint filter; integral imaging; elemental images
Satisfaction with processes of collecting student opinions about instruction: The student perspective.

This study used a 2×2×2 factorial experiment to examine student satisfaction with eight processes of collecting student ratings of instruction by varying a) method (group interviews vs. individual standardized rating forms), b) timing (midterm vs. end of course), and c) amount of instructor reaction to student ratings (restricted vs. extended)
Inhibition of Human Coronavirus NL63 Infection at Early Stages of the Replication Cycle

ABSTRACT Human coronavirus NL63 (HCoV-NL63), a recently discovered member of the Coronaviridae family, has spread worldwide and is associated with acute respiratory illness in young children and elderly and immunocompromised persons. Further analysis of HCoV-NL63 pathogenicity seems warranted, in particular because the virus uses the same cellular receptor as severe acute respiratory syndrome-associated coronavirus. As there is currently no HCoV-NL63-specific and effective vaccine or drug therapy available, we evaluated several existing antiviral drugs and new synthetic compounds as inhibitors of HCoV-NL63, targeting multiple stages of the replication cycle. Of the 28 compounds that we tested, 6 potently inhibited HCoV-NL63 at early steps of the replication cycle. Intravenous immunoglobulins, heptad repeat 2 peptide, small interfering RNA1 (siRNA1), siRNA2, β-d-N4-hydroxycytidine, and 6-azauridine showed 50% inhibitory concentrations of 125 μg/ml, 2 μM, 5 nM, 3 nM, 400 nM, and 32 nM, respectively, and low 50% cytotoxicity concentrations (>10 mg/ml, >40 μM, >200 nM, >200 nM, >100 μM, and 80 μM, respectively). These agents may be investigated further for the treatment of coronavirus infections.
The articulation of knowledge managementstrategy in public sector organizations

The common de facto of a KM strategy needs to move beyond outlining ‘know-how’ goals such as ‘becoming a knowledge-enabled enterprise’ to the realities of ‘know-why’. In fact the latter may prove to be more significant as it denotes levels of creativity and innovation which are key drivers to organizational performance.As such, the strategy must identify the key needs and issues within the organization and provide a framework for addressing these.This paper provides an approach in articulating the KM strategy which focused on the significance and impact of value propositions.
Protecting the Marriage Relationship During the Doctoral Journey

With doctoral programs across disciplines experiencing perennially high attrition rates, in-depth examination of factors associated with doctoral persistence is necessary. A strong marital relationship is one factor found to be central to persistence in doctoral students. Thus, the purpose of this article is to provide an overview of the literature on marital satisfaction, quality, and stability in order to provide doctoral students and their partners strategies for nurturing and sustaining a solid marriage throughout the stress-inducing doctoral process. Recommendations are framed by the following four factors of the Sound Marital House: (a) marital friendship, (b) creating positive sentiment override, (c) regulating conflict, and (d) creating shared symbolic meaning.
Efficient distance computation between non-convex objects

This paper describes an efficient algorithm for computing the distance between nonconvex objects. Objects are modeled as the union of a set of convex components. From this model we construct a hierarchical bounding representation based on spheres. The distance between objects is determined by computing the distance between pairs of convex components using preexisting techniques. The key to efficiency is a simple search routine that uses the bounding representation to ignore most of the possible pairs of components. The efficiency can further be improved by accepting a relative error in the returned result. Several empirical trials are presented to examine the performance of the algorithm. <<ETX>>
Immunohistochemical analysis of cyclooxygenase‐2 and brain fatty acid binding protein expression in grades I‐II meningiomas: Correlation with tumor grade and clinical outcome after radiotherapy

This study was done to evaluate the association of cyclooxygenase 2 (COX‐2) and brain fatty acid binding protein (BFABP) with tumor grade and outcome of grades I‐II meningiomas treated with radiotherapy. From 1996 to 2008, 40 patients with intracranial grades I‐II meningiomas were treated with radiotherapy. Immunohistochemical staining for COX‐2 and BFABP were performed on formalin‐fixed paraffin‐embedded tissues. COX‐2 expression was significantly associated with BFABP status and both COX‐2 (P < 0.01) and BFABP (P = 0.01) expression were stronger in the grade II meningiomas than in grade I tumors. Among the clinicopathologic factors, age and COX‐2 status were prognostic in progression‐free survival. Patients with moderate or strong COX‐2 expression had worse outcome than those with negative or weak COX‐2 expression (P = 0.03) after controlling for potential confounders. Our results suggest that the molecular biomarker COX‐2 has prognostic significance in intracranial grades I‐II meningiomas following radiotherapy.
On the feasibility of centrally-coordinated Peer-to-Peer live streaming

In this paper we present an exploration of central coordination as a way of managing P2P live streaming overlays. The main point is to show the elements needed to construct a system with that approach. A key element in the feasibility of this approach is a near real-time optimization engine for peer selection. Peer organization in a way that enables high bandwidth utilization plus optimized peer selection based on multiple utility factors make it possible to achieve large source bandwidth savings and provide high quality of user experience. The benefits of our approach are also seen most when NAT constraints come into play.
Cross-layer design for resource allocation in 3G wireless networks and beyond

Cross-layer design approaches are critical for efficient utilization of the scarce radio resources with QoS provisioning in the third-generation wireless networks and beyond. Better system performance can be obtained from information exchanges across protocol layers, which may not be available in the traditional layering architecture. This article provides an overview of cross-layer design approaches for resource allocation in 3G CDMA networks, summarizes state-of-the-art research results, and suggests further research issues. In addition, a cross-layer design approach for real-time video over time-varying CDMA channels is proposed, where link layer resource allocation benefits from information in both the application and physical layers. Simulations results are given to demonstrate the effectiveness of the proposed approach.
Delusional misidentification in association with cortical lewy body disease—a case report and overview of possible mechanisms

A patient presented with a Capgras delusion and reduplication of place. At postmortem there were numerous cortical Lewy bodies. This is believed to be the first such case in which these phenomena have been observed in proven cortical Lewy body disease. The clinical and diagnostic features are described and a brief overview of possible explanations for the phenomena discussed.
Urinary osteocalcin and other markers of bone metabolism: the effect of risedronate therapy

Objective. Serum osteocalcin (S‐OC) is widely used as an index of bone formation. However, there is evidence that some urinary fragments of OC reflect resorption and might be useful in monitoring antiresorptive therapy. Here, we report 6‐month changes in urinary midfragments of osteocalcin (U‐MidOC) and other bone turnover markers in response to risedronate treatment. Material and methods. The study group comprised 19 patients with postmenopausal osteoporosis, aged 49–66 years, and receiving risedronate therapy. Fifty‐four premenopausal women served as controls. Osteoporosis was diagnosed by lumbal bone mineral density (BMD). Urinary osteocalcin was measured by the U‐MidOC assay for midfragments. Bone formation was assessed by S‐PINP and S‐OC, and resorption by S‐CTx‐I. Results. At baseline, U‐MidOC was significantly correlated only with S‐OC. After the 1st month of therapy, a similar decrease was observed in the values of U‐MidOC and S‐CTx‐I, but in formation markers S‐P1NP and S‐OC only after three months. The rapid decrease in U‐MidOC, analogous to S‐CTX‐I, and the different kinetics for urinary and serum OC suggest that urinary OC midfragments are more associated with resorption than S‐OC. An association was also observed between the 1‐month change in U‐MidOC and 12‐month gain in lumbar BMD. The response in U‐MidOC after only the 1st month of therapy makes it a potential marker for monitoring the effect of risedronate, presumably reflecting different aspects of bone resorption than S‐CTx‐I does.
The striatum and beyond: contributions of the hippocampus to decision making

Recent research on the neural bases of decision making has focused on the role of the striatum and dopamine in learning to predict and obtain rewards. These studies have illuminated the processes by which repeated experiences of choice and reward feedback lead to the updating of value representations, allowing an organism to use past experience to improve choices when encountering the same situation. However, in a constantly changing environment, choices may not repeat themselves. Instead, decisions often involve novel contexts and options, requiring flexible generalization of past experience to novel choices. Extensive evidence from studies of the neural bases of learning and memory suggests that flexible use of learned knowledge depends on a “declarative” memory system in the hippocampus. Investigations of the neural bases of decision making and of memory systems have developed largely independently of each other. However, there are a number of important links between them, at both the brain and behavioral levels. Here, we briefly review these two literatures and propose a critical role for the hippocampus in decision making when past experience must be flexibly generalized to new situations. Further, we suggest that dopamine modulates learning in both the striatum and the hippocampus, with these two systems working together to adaptively guide choices. Finally, we present behavioral evidence from a novel paradigm designed to probe the role of hippocampal-dependent memory in decision making. The findings demonstrate that past experience can flexibly guide decision making in novel contexts, indicating a possible cooperation between reinforcement history and declarative memories in guiding decision making.
Corpus for Customer Purchase Behavior Prediction in Social Media

Many people post about their daily life on social media. These posts may include information about the purchase activity of people, and insights useful to companies can be derived from them: e.g. profile information of a user who mentioned something about their product. As a further advanced analysis, we consider extracting users who are likely to buy a product from the set of users who mentioned that the product is attractive. In this paper, we report our methodology for building a corpus for Twitter user purchase behavior prediction. First, we collected Twitter users who posted a want phrase + product name: e.g. “want a Xperia” as candidate want users, and also candidate bought users in the same way. Then, we asked an annotator to judge whether a candidate user actually bought a product. We also annotated whether tweets randomly sampled from want/bought user timelines are relevant or not to purchase. In this annotation, 58% of want user tweets and 35% of bought user tweets were annotated as relevant. Our data indicate that information embedded in timeline tweets can be used to predict purchase behavior of tweeted products.