Miracle-dz/UniFAR-FTUs huggingface dataset:
Glycemic control and neuropsychologic function during hypoglycemia in patients with insulin-dependent diabetes mellitus.

STUDY OBJECTIVE To evaluate counterregulatory hormone secretion and neuropsychologic function during hypoglycemia in two groups of patients with insulin-dependent diabetes mellitus: those with good and those with poor glycemic control. DESIGN Cross-sectional physiologic and neuropsychologic evaluation. SETTING Clinical research unit of a referral-based diabetes clinic. PATIENTS Eight patients with well controlled diabetes (glycosylated hemoglobin [HgbA1], 8.0% +/- 0.2%), nine patients with poorly controlled diabetes (HgbA1, 11.8% +/- 0.4%), and ten healthy persons. INTERVENTIONS The insulin clamp technique was used to produce a stepwise decline in plasma glucose from 5.0 to 2.2 mmol/L over 3 hours. Tests of attention, memory, visual-spatial skills, visual-motor skills, and global cognition; a symptom survey; and counterregulatory hormone measurements were done at glucose decrements of 0.6 mmol/L. MEASUREMENTS AND MAIN RESULTS Patients with well controlled diabetes did not differ statistically from those with poorly controlled diabetes regarding the median glucose threshold for dysfunction in visual-spatial skills, visual-motor skills, or global cognition. In contrast, glycemic thresholds for an increase in adrenergic symptoms and release of epinephrine, norepinephrine, cortisol, and growth hormone were lower in patients with well controlled diabetes than in those with poorly controlled diabetes (P less than 0.05 to 0.005). CONCLUSIONS Despite alterations in the glucose levels at which adrenergic symptoms of hypoglycemia occur and counterregulation begins, there is no statistically detectable change in the glucose threshold at which cognitive deterioration occurs in diabetic persons with strict glycemic control. This dissociation of neuropsychologic function and counterregulatory hormone secretion suggests that diabetic patients with good glycemic control are at increased risk for developing cognitive impairment before the onset of adrenergic symptoms during hypoglycemia.
A Genetic Linkage Map of Atlantic Halibut (Hippoglossus hippoglossus L.)

A genetic linkage map has been constructed for Atlantic halibut on the basis of 258 microsatellites and 346 AFLPs. Twenty-four linkage groups were identified, consistent with the 24 chromosomes seen in chromosome spreads. The total map distance is 1562.2 cM in the female and 1459.6 cM in the male with an average resolution of 4.3 and 3.5 cM, respectively. Using diploid gynogens, we estimated centromere locations in 19 of 24 linkage groups. Overall recombination in the female was approximately twice that of the male; however, this trend was not consistent along the linkage groups. In the centromeric regions, females had 11–17.5 times the recombination of the males, whereas this trend reversed toward the distal end with males having three times the recombination of the females. Correspondingly, in the male, markers clustered toward the centromeric region with 50% of markers within 20 cM of the putative centromere, whereas 35% of markers in the female were found between 60 and 80 cM from the putative centromere. Limited interspecies comparisons within Japanese flounder and Tetraodon nigroviridis revealed blocks of conservation in sequence and marker order, although regions of chromosomal rearrangement were also apparent.
Data mining of Gene expression profiles of Saccharomyces cerevisiae in response to mild heat stress response

We chose yeast as a model organism to explore how eukaryotic cells respond to heat stress. This study provides details on the way yeast responds to temperature changes and is therefore an empirical reference for basic cell research and industrial fermentation of yeast. We use the Qlucore Omics Explorer (QOE) bioinformatics software to analyze the gene expression profiles of the heat stress from Gene Expression Omnibus (GEO). Genes and their expression are listed in heat maps, and the gene function is analyzed against the biological processes and pathways. We can find that the expression of genes changed over time after heat stress. Gene expression changed rapidly from 0 min to 60 min after heat shock, and gene expression stabilized between 60 min to 360 min. The yeast cells begin to adjust themselves to the high temperatures in terms of the level of gene expression at about 60 min. In all of the involved pathways and biological processes, those related to ribosome and nucleic acid metabolism declined in about 15–30 min and those related to starch and sucrose increased in the same time frame. Temperature can be a simple way to control the biological processes and pathways of cell.
Thrombin Time Dilution Test: A Simple Method for the Control of Heparin Therapy

Summary A modification of the thrombin time test (TT), which permits quantitative measurement of plasma heparin activity during therapy is described. The prolonged TT of plasma containing heparin can be corrected by dilution with platelet-rich plasma (PRP). Clinical heparin activity is considered adequate when prolonged TT of the plasma can be corrected at dilutions of from 1:4 to 1:8 (±20%). In vitro studies of 30 PRP samples containing different amounts of heparin showed that 1:4 and 1:8 dilutions did not correct prolonged TT (P<0.05) in the presence of more than 0.2 and 0.3 U of heparin/ml respectively, indicating that the adequate dose of heparin should fall between those levels which show correction at these dilutions, using the diluted TT method. Patients treated with 100 U of heparin/kg every 4 or 6 h were studied: 52 without previous coagulation defects and 22 with disseminated intravascular coagulation (DIC). The results in the first group showed adequate dosage in 29 cases, overdosage in 12 and underdosage in 11. Hemorrhage occurred in 5 of the overdosage group. In the DIC series, 4 with underdosage of heparin did not improve; in 13 of 18 with adequate dosage, both hemorrhage and coagulapathy disappeared, while the other 5, with more severe complications did not improve. Based on these findings, the diluted TT appears to be a useful test in the assessment of heparin therapy, even in patients with previous coagulation abnormalities.
Routing algorithms for balanced energy consumption in ad hoc networks

In a mobile ad hoc network (MANET), a node communicates directly with the nodes within wireless range and indirectly with other nodes using a dynamically computed, multi-hop route via the other nodes of the MANET. In order to facilitate communication within the network, a routing protocol is used to discover routes between nodes. The primary goal of such an ad hoc network routing protocol is correct and efficient route establishment between a pair of nodes so that messages may be delivered in a timely manner. Although establishing efficient routes is an important goal, a more challenging goal is to provide energy efficient routing protocols, since a critical limiting factor for a mobile node is its operation time, restricted by battery capacity. However, the wireless link-only routing path in a MANET makes energy savings difficult to achieve. The corresponding reduction of nodes' lifetime directly affects the network lifetime since mobile nodes themselves collectively form a network infrastructure for routing in a MANET. This article surveys the energy aware routing mechanisms proposed for MANETs.
Dust–radiation universes: stability analysis

In this paper we consider flat and open universe models containing a mixture of cold matter (dust) and radiation interacting only through gravity, with the aim of studying their stability with respect to linear scalar perturbations. To this end we consider the perturbed universe as a dynamical system, described by coupled differential equations for a gauge-invariant perturbation variable and a relevant background variable. The phase-space analysis of this dynamical system shows that flat dust-radiation models are unstable, and open models structurally unstable, with respect to adiabatic perturbations. For flat models, there are actually three different regimes of evolution for the perturbations, depending on their wavelength and the transition scale from one regime to the other is determined by a critical wavenumber for the perturbations, kEC (an invariant of the model). We find that kEC < kJE (the Jeans wavenumber at equidensity of matter and radiation), implying that there are perturbations which decay even if their wavelength at equidensity is larger than the corresponding Jeans scale. We also briefly discuss metric and curvature perturbations. We believe that this analysis gives a clearer idea of the stability properties of realistic universe models than the standard one based on the Jeans scale, despite our simplifying assumptions.
The effects of surface energy and roughness on the hydrophobicity of woven fabrics

The wetting behavior of a hydrophobic rough surface is investigated on a surface fabricated by applying low surface tension materials such as silicone or fluoropolymer to polyester woven fabric consisting of multifilament yarns. The roughness factor of various woven fabrics can be calculated by Wenzel’s and Cassie–Baxter’s equations. For the fabrics treated with silicone or fluoropolymer, the Cassie–Baxter model was applied, showing a level of agreement for the fabric specimens non-textured filament fibers between the predicted contact angles and the measured values. More precisely, the fabrics treated with silicone or fluoropolymer represent the transitional state between the Wenzel type and the Cassie–Baxter type; that is, the fractional contact area between the water and air f2 is greater than zero, and the sum of the fractional contact areas for solid–water f1 and air–water f2 is greater than 1. A surface with lower energy and higher roughness gave f1 + f2 close to 1 with smaller f1 and larger f2, which resulted in a high contact angle.
A Policy Change Strategy for Head Lice Management

The purpose of this project was to formulate an effective change strategy for head lice management in a group of five separate school districts within one county. Despite a desire to use evidence to support their practice, school nurses often encounter educational system barriers that prevent independent management of health conditions. The use of collaborative community relationships, identification of underlying hierarchy structures in school policy development, and targeted system education were the catalysts for changing beliefs and ultimately policy within these school districts. The focus of this project was to develop a policy change strategy for head lice. The strategy provides direction for successful health policy advocacy using evidence-based practices for other health issues within the education setting.
ffi cient Approximate Verification of B via Symmetry Markers

We present a new approximate verification technique for B models. The technique employs symmetry of B models induced by the use of deferred sets. The basic idea is to efficiently compute markers for states, which are such that symmetric states are guaranteed to have the same marker (but not the other way around). The approximate verification algorithm then assumes that two states with the same marker can be considered symmetric. We describe how symmetry markers can be efficiently computed and empirically evaluate an implementation, showing both very good performance results and a high degree of precision (i.e., very few non-symmetric states receive the same marker). We also identify a class of B models for which the technique is precise.
Oblivious transfer over OFDM and MIMO channels

We consider the problem of oblivious transfer (OT) over OFDM and MIMO wireless communication systems where only the receiver knows the channel state information. The sender and receiver also have unlimited access to a noise-free real channel. Using a physical layer approach, based on the properties of the noisy fading channel, we propose a scheme that enables the transmitter to send obliviously one-of-two files, i.e, without knowing which one has been actually requested by the receiver, while also ensuring that the receiver does not get any information about the other file.
A role for sphingosine kinase 1 in dextran sulfate sodium‐induced colitis

The bioactive lipid sphingosine‐1‐phos‐phate (S1P) is emerging as an important mediator of immune and inflammatory responses. S1P formation is catalyzed by sphingosine kinase (SK), of which the SK1 isoenzyme is activated by tumor necrosis alpha (TNF‐α). SK1 has been shown to be required for mediating TNF‐α inflammatory responses in cells, including induction of cyclooxygenase 2 (COX‐2). Because TNF‐α and COX‐2 are increased in patients with inflammatory bowel disease (IBD), we investigated the role of SK1 in a murine model of colitis. SK1–/– mice treated with dextran sulfate sodium (DSS) had significantly less blood loss, weight loss, colon shortening, colon histo‐logical damage, and splenomegaly than did wild‐type (WT) mice. In addition, SK1–/– mice had no systemic inflammatory response. Moreover, WT but not SK1–/– mice treated with dextran sulfate sodium had signifi‐cant increases in blood S1P levels, colon SK1 message and activity, and colon neutrophilic infiltrate. Unlike WT mice, SK1–/– mice failed to show colonic COX‐2 induction despite an exaggerated TNF‐α response; thus implicating for the first time SK1 in TNF‐α‐mediated COX‐2 induction in vivo. Inhibition of SK1 may prove to be a valuable therapeutic target by inhibiting sys‐temic and local inflammation in IBD. —Snider, A. J., Kawamori, T. , Bradshaw, S. G. , Orr, K. A. , Gilkeson, G. S. , Hannun, Y. A. , Obeid, L. M. A role for sphin‐gosine kinase 1 in dextran sulfate sodium‐induced colitis. FASEBJ. 23, 143‐152 (2009)
Personalized Voice Search for Internet TV

In this paper, we discuss various strategies that have helped address the unique set of challenges we have faced in the attempt to provide highly relevant and personalized voice search results to users of our Internet TV (a.k.a. IPTV) system. While movie recommender systems have been heavily studied in the academia [1] as well as in the industry [2], full TV recommender systems are less prevalent and require a deeper understanding of real-world complex scenarios, such as using voice search as a mechanism for providing an easy-to-use interface for content search and discovery in IPTV platforms. It also requires the generation of fresh, domain-specific, relevant and highly contextual search results and recommendations within the constraints of what is playable and what is not; whether the suggested programs come from airings currently available from live/linear channels, time-shifted (a.k.a. catch-up) TV, digital video recordings (DVR) or video-on-demand (VOD), or from future airings that may not yet be available but may still be of interest to users to subsequently follow and/or record them.
Real-time robust recognition of speakers' emotions and characteristics on mobile platforms

We demonstrate audEERING's sensAI technology running natively on low-resource mobile devices applied to emotion analytics and speaker characterisation tasks. A showcase application for the Android platform is provided, where au-dEERING's highly noise robust voice activity detection based on Long Short-Term Memory Recurrent Neural Networks (LSTM-RNN) is combined with our core emotion recognition and speaker characterisation engine natively on the mobile device. This eliminates the need for network connectivity and allows to perform robust speaker state and trait recognition efficiently in real-time without network transmission lags. Real-time factors are benchmarked for a popular mobile device to demonstrate the efficiency, and average response times are compared to a server based approach. The output of the emotion analysis is visualized graphically in the arousal and valence space alongside the emotion category and further speaker characteristics.
A minimum power-processing stage fuel cell energy system based on a boost-inverter with a bi-directional back-up battery storage

When low-voltage unregulated fuel cell (FC) output is conditioned to generate AC power, two stages are required: a boost stage and an inversion one. In this paper, the boost-inverter topology that achieves both boosting and inversion functions in a single-stage is used to develop an FC-based energy system which offers high conversion efficiency, low-cost and compactness. The proposed system incorporates additional battery-based energy storage and a DC-DC bi-directional converter to support instantaneous load changes. The output voltage of the boost-inverter is voltage-mode controlled and the DC-DC bidirectional converter is current-mode controlled. The load low-frequency current ripple is supplied by the battery which minimizes the effects of such ripple being drawn directly from the FC itself. Analysis, simulation and experimental results are presented to confirm the operational performance of the proposed system.
A General Regression Test Selection Technique

— This paper presents a new methodology to select test cases from regression test suites. The selection strategy is based on analyzing the dynamic behavior of the applications that written in any programming language. Methods based on dynamic analysis are more safe and efficient. We design a technique that combine the code based technique and model based technique, to allow comparing the object oriented of an application that written in any programming language. We have developed a prototype tool that detect changes and select test cases from test suite.
Vertigo: Programmable Micro-controllers for Software-Defined Object Storage

Software-defined storage (SDS) aims to minimize the complexity of data management in the Cloud. SDS decouples the control plane from the data plane and simplifies the management of the storage system via automated storage policy enforcement. In this paper, we propose a novel SDS framework for Object Storage that allows to decentralize policy enforcement through the deployment of per-object management policies in the storage nodes. As in active storage systems, we leverage the underutilized CPU time in the storage nodes. But our framework goes one step further. It provides a new management abstraction called micro-controllers which operate on objects depending on their state and content, thereby permitting the implementation of sophisticated management policies, such as the automated deletion of an object based on its access history, and even allowing the orchestration of active storage tasks. Our SDS system avoids the massive interception of data flows by moving that logic to the appropriate objects. Furthermore, our extensible model simplifies the customization of Object Storage services. We present in the validation several interesting use cases such as automated deletion, content level access control, and Web prefetching.
Controlling oxygen vacancies in doped oxide based CBRAM for improved memory performances

In this paper the concept hybrid CBRAM assisted by oxygen vacancies is presented for the 1<;sup>st<;/sup> time. Doping the resistive layer of oxide/Cu based CBRAM with <; dopant species and concentrations is proposed in order to improve the memory performances. By means of experimental characterizations, numerical model and atomistic calculations, we demonstrate that increasing the doping content ease the filament formation by facilitating the Cu injection in the resistive layer. The proper choice of the doping element and concentration allows to significantly reduce the forming voltage (up to a forming free behavior), or alternatively to increase the memory window of 3 decades, with no forming voltage increase and retention degradation (stable behavior at 200°C, 260°C soldering sustained).
Sensitivity analysis of dynamic tariff method for congestion management in distribution networks

The dynamic tariff (DT) method is designed for the distribution system operator (DSO) to alleviate the congestions that might occur in a distribution network with high penetration of distribute energy resources (DERs). Sensitivity analysis of the DT method is crucial because of its decentralized control manner. The sensitivity analysis can obtain the changes of the optimal energy planning and thereby the line loading profiles over the infinitely small changes of parameters by differentiating the KKT conditions of the convex quadratic programming, over which the DT method is formed. Three case studies were conducted to demonstrate the impact of small and big changes of parameters on the line loading profiles and the effectiveness of the DT method.
Neutron irradiation and dc transport in YBaCuO single crystals : a study of vortex depinning

approved: Janet Tate Four-terminal dc V-I characteristics of the high-temperature superconducting copper-oxides are usually analyzed within the framework of a second-order vortex glass-to-liquid phase transition. Such an analysis depends on universal critical parameters, but a definitive universality class has not emerged in the literature. The nature of vortex depinning in the mixed state of disordered YBa2C u30 (YBCO) continues to be a subject of controversy. This work presents dc V-I traces on heavily-twinned YBCO crystals for a variety of applied magnetic fields and precisely stabilized temperatures. To study the effect of disorder, data are collected before and after fast-neutron irradiation. The data show a systematic dependence on the disorder in the vortex array due to pinning. Specifically, the logarithmic derivative, n, of data at the depinning temperature depends on an estimate of the LarkinOvchinnikov pinning length for the YBCO crystals and for data selected from the literature. The YBCO crystal data can be collapsed with critical scaling, but they do not yield universal exponents. A less familiar analysis is used to map critical current distributions which show sensitivity to temperature, field, and pinning-site density. Given that critical parameters of the glass-toliquid phase transitions depend on n, and given the results of a simulation based on thermal depinning, this thesis concludes that dc V-I data do not provide satisfactory evidence of a glass-liquid phase transition. Overall, the data are most adequately described by dislocation-mediated thermal depinning, or percolation. © Copyright by Brandon R. Brown May 8, 1997 All Rights Reserved Neutron Irradiation and dc Transport in YBaCuO Single Crystals: A Study of Vortex Depinning