Miracle-dz/UniFAR-FTUs huggingface dataset:
DACoRM: A coordinated, decentralized and adaptive network resource management scheme

In order to meet the requirements of emerging demanding services, network resource management functionality that is decentralized, flexible and adaptive to traffic and network dynamics is of paramount importance. In this paper we describe the main mechanisms of DACoRM, a new intra-domain adaptive resource management approach for IP networks. Based on path diversity provided by multi-topology routing, our approach controls the distribution of traffic load in the network in an adaptive manner through periodical re-configurations that uses real-time monitoring information. The re-configuration actions performed are decided in a coordinated fashion between a set of source nodes that form an in-network overlay. We evaluate the overall performance of our approach using realistic network topologies. Results show that near-optimal network performance in terms of resource utilization can be achieved in scalable manner.
One year outcome in mild to moderate head injury: the predictive value of acute injury characteristics related to complaints and return to work

OBJECTIVES To determine the prognostic value of characteristics of acute injury and duration of post-traumatic amnesia (PTA) for long term outcome in patients with mild to moderate head injury in terms of complaints and return to work. METHODS Patients with a Glasgow coma score (GCS) on admission of 9–14 were included. Post-traumatic amnesia was assessed prospectively. Follow up was performed at 1, 3, 6, and 12 months after injury. Outcome was determined by the Glasgow outcome scale (GOS) 1 year after injury and compared with a more detailed outcome scale (DOS) comprising cognitive and neurobehavioural aspects. RESULTS Sixty seven patients were included, mean age 33.2 (SD 14.7) years and mean PTA 7.8 (SD 7.3) days. One year after injury, 73% of patients had resumed previous work although most (84%) still reported complaints. The most frequent complaints were headache (32%), irritability (34%), forgetfulness and poor concentration (42%), and fatigue (45%). According to the GOS good recovery (82%) or moderate disability (18%) was seen. Application of the DOS showed more cognitive (40%) and behavioural problems (48%), interfering with return to work. Correlation between the GOS and DOS was high (r=0.87, p<0.01). Outcome correlated with duration of PTA (r=−0.46) but not significantly with GCS on admission (r=0.19). In multiple regression analysis, PTA and the number of complaints 3 months after injury explained 49% of variance on outcome as assessed with the GOS, and 60% with the DOS. CONCLUSIONS In mild to moderate head injury outcome is determined by duration of PTA and not by GCS on admission. Most patients return to work despite having complaints. The application of a more detailed outcome scale will increase accuracy in predicting outcome in this category of patients with head injury.
Distribution of Erythrocyte Nucleotides in Pyrimidine 5′‐Nucleotidase Deficiency

Summary. In pyrimidine 5′‐nucleotidase deficiency, erythrocytes contain elevated levels of pyrimidine nucleotides. The composition of this nucleotide pool was examined by ion exchange chromatography on Dowex formate columns using a linear ammonium formate elution gradient. In contradistinction to normal erythrocytes, adenine nucleotides accounted for only 32% of the nucleotide pool. The remainder consisted of 50% cytidine and 16% uridine nucleotides. The remaining 2% was not identified. The most abundant compound appeared to be UDP glucose whilst high levels of CTP, CMP and an unidentified cytidine compound less polar than CMP accounted for most of the cytidine nucleotide pool. The possibility that the abnormal nucleotides were due to an elevated reticulocyte count was excluded and it was also shown that erythrocytes from subjects heterozygous for pyrimidine 5′‐nucleotidase deficiency did not have detectable levels of the abnormal nucleotides.
Nerve fibre size in the carpal tunnel syndrome

The syndrome due to compression of the median nerve in the carpal tunnel was first defined by Ramsey Hunt (1911, 1914) and Marie and Foix (1913), although its relationship to the acroparaesthesia syndrome was not appreciated until recently (see Kremer, Gilliatt, Golding, and Wilson, 1953). Marie and Foix (1913) examined the pathological changes in a single case, but no further studies on the histological alterations in this condition have appeared since. Recently, the opportunity presented itself for such an examination in a patient who died from an unrelated disorder. Particular attention has been given to alterations in nerve fibre size, which are of interest in relation to the changes that occur in nerve conduction (Simpson, 1956; Carpendale, 1956; Thomas, 1960).
A Taxonomy of Privacy Constructs for Privacy-Sensitive Robotics

The introduction of robots into our society will also introduce new concerns about personal privacy. In order to study these concerns, we must do human-subject experiments that involve measuring privacy-relevant constructs. This paper presents a taxonomy of privacy constructs based on a review of the privacy literature. Future work in operationalizing privacy constructs for HRI studies is also discussed.
A Multistage Agglomerative Approach for Defining Functional Regions of the Czech Republic: The Use of 2001 Commuting Data/ Vícestupňový aglomerační přístup k vymezení funkčních regionů České republiky: využití údajů o dojížďce z roku 2001

Abstract The issue of defining functional regions in the Czech Republic is presented in this paper, which contributes to both theoretical discussions (e.g. the modifiable areal unit problem) and practical applications (e.g. spatial administration, regional planning). A multistage agglomerative approach to functional regional taxonomy is applied, which has been used in Czech geographical research for the first time only recently. The regionalisation algorithm provided four optional solutions for this issue, based on the analysis of daily travel-to-work flows from the 2001 census. The resulting regions correspond to the micro-regional level and two additional tiers were identified at this level. The basic statistics for all variants are presented. Shrnutí Článek se zabývá problémem vymezení funkčních regionů na území České republiky a přispívá jak k teoretické diskusi (např. problém modifikovatelné územní jednotky) tak k praktickým aplikacím (např. prostorová správa, regionální plánování). Je aplikován vícestupňový aglomerační přístup k funkční regionální taxonomii, jenž byl v české geografii použit poprvé zcela nedávno. Regionalizační algoritmus poskytl čtyři variantní řešení založené na analýze denních toků do zaměstnání z censu z roku 2001. Výsledné regiony odpovídají mikroregionální úrovni a v rámci této úrovně byly identifikovány další dva stupně. Ke všem variantám jsou rovněž uvedeny základní statistiky.
Low frequency variability of tropical cyclone potential intensity 1. Interannual to interdecadal variability

[1] Recent research suggests that anthropogenic global warming would be associated with an increase in the intensity of tropical cyclones. A recent statistical analysis of observed tropical cyclone intensity shows that its variability with location and season is strongly tied to the variability of the thermodynamic potential intensity (PI) of tropical cyclones, as calculated using a theory described in an earlier work by the authors. Thus it is of interest to look for possible trends in global measures of PI, which are far more stable than those of actual storm intensity. We estimate global trends of PI from 1958 to 1996, averaged over the region where it exceeds 40 m s−1, using the National Centers for Environmental Prediction/National Center for Atmospheric Research (NCEP/NCAR) Reanalysis and the NCEP Empirical Orthogonal Function (EOF) sea surface temperature (SST) analysis. We adjust the Reanalysis temperatures for a large, spurious temperature increase that occurred around 1979. We do this by subtracting from the Reanalysis the atmospheric temperature difference between pairs of years with similar tropical SST before and after 1979. The value of the global mean PI is very large for the SST of the corresponding region in the mid-1990s. Supported by a recent study on the effects of ozone decrease on tropospheric temperatures, we suggest that the ozone decrease might be one of the factors contributing to increase of PI during the 1990s.
Personal mobility pattern mining and anomaly detection in the GPS era

Abstract Suffering from Alzheimer’s disease has become one of the critical health issues today. If an abnormal time–space pattern of such patients can be detected earlier, it will help the families to prevent some dangerous situations in advance. We have proposed a method in this study to uncover personal mobility patterns and detect abnormal behavior patterns from mobility data obtained with global position system (GPS). Experimental results showed that our proposed method is far better than other alternatives available. This proposed approach may thus render great assistance in identifying abnormal behavior, thus providing critical remedy actions in advance in this GPS era.
Sentiment Analysis with Global Topics and Local Dependency

With the development of Web 2.0, sentiment analysis has now become a popular research problem to tackle. Recently, topic models have been introduced for the simultaneous analysis for topics and the sentiment in a document. These studies, which jointly model topic and sentiment, take the advantage of the relationship between topics and sentiment, and are shown to be superior to traditional sentiment analysis tools. However, most of them make the assumption that, given the parameters, the sentiments of the words in the document are all independent. In our observation, in contrast, sentiments are expressed in a coherent way. The local conjunctive words, such as “and” or “but”, are often indicative of sentiment transitions. In this paper, we propose a major departure from the previous approaches by making two linked contributions. First, we assume that the sentiments are related to the topic in the document, and put forward a joint sentiment and topic model, i.e. Sentiment-LDA. Second, we observe that sentiments are dependent on local context. Thus, we further extend the Sentiment-LDA model to Dependency-Sentiment-LDA model by relaxing the sentiment independent assumption in Sentiment-LDA. The sentiments of words are viewed as a Markov chain in Dependency-Sentiment-LDA. Through experiments, we show that exploiting the sentiment dependency is clearly advantageous, and that the Dependency-Sentiment-LDA is an effective approach for sentiment analysis.
Faster and simpler algorithm for sorting signed permutations by reversals

We give a quadratic algorithm for finding the minimum number of reversals needed to sort a signed permutation. Our algorithm is faster than the previous algorithm of Hannenhalli and Pevzner and its faster implementation of Berman and Hannenhalli. The algorithm is conceptually simple and does not require special data structures. Our study also considerably simplifies the combinatorial structures used by the analysis. 2 refs.
Decoupling the Bandwidth and Latency Bounding for Table-based Schedulers

The provision of quality of service (QoS) in computing and communication environments is currently the focus of much discussion and research in industry and academia. A key component for networks with QoS support is the output scheduling algorithm. Some of the latest network technology proposals define scheduling algorithms that use an arbitration table to select the next packet to be transmitted. These table-based schedulers are simple to implement and can offer good latency performance. However, the versions proposed until now do not work properly with variable packet sizes. Moreover, they face the problem of bounding the bandwidth and latency assignments. In this paper, we propose a new table-based scheduler, which we call deficit table (DTable), that works properly with variable packet sizes. We also propose a methodology to decouple the bandwidth and latency assignments
Endoproteolytic Cleavage of Human Thyroperoxidase

Human thyroperoxidase (hTPO), the key enzyme involved in thyroid hormone synthesis, is synthesized in the form of a 933-amino acid polypeptide that subsequently undergoes posttranslational modifications such as N- and O-glycosylation and heme fixation. In the present study, it was established that the N-terminal part of hTPO is cleaved during the maturation of the enzyme. In the first set of experiments performed in this study, Chines hamster ovary (CHO) cells transfected with hTPO cDNA generated four different species after deglycosylation, namely a 98-kDa species, which corresponds to the full-length deglycosylated hTPO, and two 94-kDa and one 92-kDa species, which were truncated in the N-terminal parts. The three latter forms were detected only at the cell surface. A proprotein convertase inhibitor prevented these cleavages, and experiments using monensin and brefeldin A showed that they occurred in a post-endoplasmic reticulum compartment. Site-directed mutagenesis studies were performed in which Arg65 was identified as one of the cleavage sites. In the second part of the study, hTPO from human thyroid glands was purified using a monoclonal antibody recognizing the folded form of hTPO. Amino acid determination showed that the N-terminal part of this protein begins at Thr109. This cleavage process differs from that observed in CHO cells. The fact that this hTPO was endoglucosaminidase H-sensitive indicated that the cleavage of the propeptide occurs in the endoplasmic reticulum. To analyze the role of the hTPO prosequence, cDNAs with and without prosequence (Cys15–Lys108) were transfected into CHO cells. hTPO propeptide deletion drastically decreased the proportion of the folded hTPO form, and under these conditions the cell surface activity disappeared completely. These results strongly suggest that the prosequence plays a crucial role as an intramolecular chaperone, facilitating the folding of hTPO.
MELB-YB: Preposition Sense Disambiguation Using Rich Semantic Features

This paper describes a maxent-based preposition sense disambiguation system entry to the preposition sense disambiguation task of the SemEval 2007. This system uses a wide variety of semantic and syntactic features to perform the disambiguation task and achieves a precision of 69.3% over the test data.
Simulating secondary organic aerosol from missing diesel-related intermediate-volatility organic compound emissions during the Clean Air for London (ClearfLo) campaign

Abstract. We present high-resolution (5 km × 5 km) atmospheric chemical transport model (ACTM) simulations of the impact of newly estimated traffic-related emissions on secondary organic aerosol (SOA) formation over the UK for 2012. Our simulations include additional diesel-related intermediate-volatility organic compound (IVOC) emissions derived directly from comprehensive field measurements at an urban background site in London during the 2012 Clean Air for London (ClearfLo) campaign. Our IVOC emissions are added proportionally to VOC emissions, as opposed to proportionally to primary organic aerosol (POA) as has been done by previous ACTM studies seeking to simulate the effects of these missing emissions. Modelled concentrations are evaluated against hourly and daily measurements of organic aerosol (OA) components derived from aerosol mass spectrometer (AMS) measurements also made during the ClearfLo campaign at three sites in the London area. According to the model simulations, diesel-related IVOCs can explain on average ∼ 30 % of the annual SOA in and around London. Furthermore, the 90th percentile of modelled daily SOA concentrations for the whole year is 3.8 µg m−3, constituting a notable addition to total particulate matter. More measurements of these precursors (currently not included in official emissions inventories) is recommended. During the period of concurrent measurements, SOA concentrations at the Detling rural background location east of London were greater than at the central London location. The model shows that this was caused by an intense pollution plume with a strong gradient of imported SOA passing over the rural location. This demonstrates the value of modelling for supporting the interpretation of measurements taken at different sites or for short durations.
A Contribution to Pollen Rain Characterization in Forest-Savanna Mosaics of the Venezuelan Guayana and Its Use in Vegetation Reconstructions from Sedimentary Records

The main results of a study of pollen representation in surface soils from different plant communities in the upland savannas of Guayana were presented. The representation of savanna herb pollen mainly belonging to the Poaceae and Cyperaceae was high in open communities such as fernlands, grasslands and Mauritia palm swamps, but decreased as vegetation structure became more closed and woody; from savanna-forest borders to secondary forests and lastly, evergreen montane forests; mimicking the gradient of vegetation openness observed in living plant communities. Thus, the proportion of savanna herb pollen in herbaceous communities: swamps, fernlands and grasslands, reached over 80% and arboreal pollen contributed less than 10%. This ratio changed in savanna-forest borders where savanna herb pollen decreased to 60% or less and the proportion of arboreal pollen rose to 30% or higher. Lastly, in forest soils, pollen abundances from trees (Dimorphandra, Protium, Schefflera), shrubs (Miconia and other Melastomataceae) and lianas contributed higher than 60% of the pollen sum, even in open gallery forests and fallows. The lack of pollen from cassava, the main crop in the forests of the region, at these sites was remarkable. The ordination of sediment samples from 4 records from the Late Holocene with respect to the soil surface samples studied, showed that the characterization of pollen rain was useful for identifying long-term compositional and structural changes in the sedimentary records, thus providing objective indicators for the interpretation of past vegetation structure.
The EFTOS voting farm: a software tool for fault masking in message passing parallel environments

We present a set of C functions implementing a distributed software voting mechanism for EPX or similar message passing environments, and we place it within the EFTOS framework (Embedded Fault-Tolerant Supercomputing) of software tools for enhancing the dependability of a user application. The described mechanism can be used for instance to implement restoring organs, i.e. modular redundancy systems with N-replicated voters. We show that, besides structural design goals like fault transparency, this tool achieves replication transparency, a high degree of flexibility and ease of use, good performance, as well as the possibility to combine fault masking with recovery techniques.
Localization of TraC, a protein involved in assembly of the F conjugative pilus

TraC is one of the proteins encoded by the F transfer region of the F conjugative plasmid which is required for the assembly of F pilin into the mature F pilus structure. Overproduction of this protein from the plasmid pKAS2, which carries only traC, resulted in the formation of inclusion bodies from which soluble TraC was purified. When small amounts of TraC were produced from pKAS2, the protein was localized to the cytoplasm by using anti-TraC antibodies. Similar analysis of a set of TraC-alkaline phosphatase fusion proteins localized all of these fusion proteins to the cytoplasm. However, when TraC was expressed from the F plasmid, much of it appeared associated with the bacterial membrane fraction. Under these conditions, TraC does not appear to be part of the tip of the F pilus, as neither anti-TraC antibodies nor purified TraC had any effect on the infection of F-containing bacteria by the filamentous bacteriophage f1. These data suggest that TraC is normally associated with the membrane through interactions with other proteins specified by the tra region. This interaction may be via the carboxyl-terminal region of the TraC protein, as a mutant TraC protein containing an Arg-Cys substitution at amino acid 811 exhibits an interaction with the membrane weaker than that of the wild-type protein in the presence of the other Tra proteins.
Do extreme climate events require extreme forcings?

The question whether extreme climate events require extreme forcings is assessed for the severe Great Plains drought during May–July 2012. This drought event had a rapid onset, and little indications or early warnings for its sudden emergence existed. The analysis of its origins is based on a dynamical seasonal climate forecast system where states of the ocean, atmosphere, land, sea ice, and atmospheric trace gases were initialized in late April 2012, and an ensemble of forecasts was made. Based on the diagnosis of a spectrum of possible outcomes for precipitation over the Great Plains from this system, it is concluded that the extreme Great Plains drought did not require extreme external forcings and could plausibly have arisen from atmospheric noise alone. Implications for developing early warning system for extreme events in general are also discussed.
Hybrid Wavelet-PSO-ANFIS Approach for Short-Term Wind Power Forecasting in Portugal

The increased integration of wind power into the electric grid, as it occurs today in Portugal, poses new challenges due to its intermittency and volatility. Wind power forecasting plays a key role in tackling these challenges. A novel hybrid approach, combining wavelet transform, particle swarm optimization, and an adaptive-network-based fuzzy inference system, is proposed in this paper for short-term wind power forecasting in Portugal. A thorough comparison is carried out, taking into account the results obtained with seven other approaches. Finally, conclusions are duly drawn.
Wnt/β-Catenin Signaling Regulates the Expression of the Ammonium Permease Gene RHBG in Human Cancer Cells

Ammonium is a metabolic waste product mainly detoxified by the liver. Hepatic dysfunction can lead to cytotoxic accumulation of circulating ammonium and to subsequent encephalopathy. Transmembrane ammonium transport is a widely spread process ensured by the highly conserved proteins of the Mep-Amt-Rh superfamily, including the mammalian Rhesus (Rh) factors. The regulatory mechanisms involved in the control of RH genes expression remain poorly studied. Here we addressed the expression regulation of one of these factors, RHBG. We identify HepG2 hepatocellular carcinoma cells and SW480 colon adenocarcinoma cells as expressing RHBG and show that its expression relies on β-catenin signaling. siRNA-mediated β-catenin knockdown resulted in significant reduction of RHBG mRNA in both cell lines. Pharmaceutical inhibition of the TCF4/β-catenin interaction or knockdown of the transcription factor TCF4 also downregulated RHBG expression. We identify a minimal RHBG regulatory sequence displaying a promoter activity and show that β-catenin and TCF4 bind to this fragment in vivo. We finally characterize the role of potential TCF4 binding sites in RHBG regulation. Taken together, our results indicate RHBG expression as a direct target of β-catenin regulation, a pathway frequently deregulated in many cancers and associated with tumorigenesis.
Relation between accuracies of genomic predictions and ancestral links to the training data

M.S. Lund, G. Su, U.S. Nielsen and G.P. Aamand a Department of Genetics and Biotechnology, Faculty of Agricultural Sciences, Aarhus University, DK-8830, Tjele, Denmark b Danish Agricultural Advisory Service, DK-8200 Aarhus N, Denmark * Corresponding author. Email: Mogens.Lund@agrsci.dk; Tel: 45 89991222; Fax: 45 89991300 ___________________________________________________________________________ Abstract