Miracle-dz/UniFAR-FTUs huggingface dataset:
The influence of match location, quality of opposition, and match status on possession strategies in professional association football

Abstract The aim of this study was to examine the effects of match location, quality of opposition, and match status on possession strategies in a professional Spanish football team. Twenty-seven matches from the 2005–2006 domestic league season were notated post-event using a computerized match analysis system. Matches were divided into episodes according to evolving match status. Linear regression analysis showed that possession of the ball was greater when losing than when winning (P < 0.01) or drawing (P < 0.05), and playing against strong opposition was associated with a decrease in time spent in possession (P < 0.01). In addition, weighted mean percentage time spent in different zones of the pitch (defensive third, middle third, attacking third) was influenced by match status (P < 0.01) and match location (P < 0.05). A combination of these variables and their interactions can be used to develop a model to predict future possession in football. The findings emphasize the need for match analysts and coaches to consider independent and interactive potential effects of match location, quality of opposition, and match status during assessments of technical and tactical components of football performance. In particular, the findings indicate that strategies in soccer are influenced by match variables and teams alter their playing style during the game accordingly.
Characterization of Land Cover Types in TerraSAR-X Images by Combined Analysis of Speckle Statistics and Intensity Information

The appearance of objects and surfaces in synthetic aperture radar (SAR) images significantly differs from the human perception of the environment. In addition, the quality of SAR data is degraded by speckle noise, superposing the true radiometric and textural information of the radar image. Hence, the interpretation of SAR images is considered to be more challenging compared to the analysis of optical data. However, in this paper, we demonstrate how information on the local development of speckle can be used for the differentiation of basic land cover (LC) types in a single-polarized SAR image. For that purpose, we specify the speckle characteristics of the following LC types: 1) water; 2) open land (farmland, grassland, bare soil); 3) woodland; and 4) urban area by means of an unsupervised analysis of scatter plots and standardized histograms of the local coefficient of variation. Next, we use this information for the implementation of a straightforward preclassification of single-polarized TerraSAR-X stripmap images by combining information on the local speckle behavior and local backscatter intensity. The output is either provided as a discrete classification or as a color composite image whose bands can be interpreted in terms of a fuzzy classification. The results of this paper show that unsupervised speckle analysis in high-resolution SAR images supplies valuable information for a differentiation of the water, open land, woodland, and urban area LC types. While the color composite image supports the visual interpretation of SAR data, the outcome of the fully automated discrete LC classification procedure represents a valuable preclassification image, showing overall accuracies of 77%-86%.
Mouse Pop1 Is Required for Muscle Regeneration in Adult Skeletal Muscle

ABSTRACT Popeye (Pop) genes are a novel gene family encoding putative transmembrane proteins predominantly present in striated and smooth muscle cells. In this study, a null mutation of Pop1 was generated by replacing the first coding exon of the Pop1 gene with the lacZ reporter gene. Homozygous mice lacking Pop1 were fertile and had a normal life span without any apparent phenotype. LacZ staining of tissues of heterozygous and homozygous Pop1-LacZ mice revealed strong expression in embryonic and fetal hearts. Pop1-LacZ was also expressed in the myotome and in myogenic progenitor cells within the limb and in smooth muscle cells of various organs. In the heart, Pop1-LacZ activity was downregulated postnatally in heterozygous mice but not in homozygous mice. Administration of the β-adrenergic agonist isoproterenol led to a rapid increase in Pop1-LacZ activity in heterozygotes without induction at the transcriptional level, suggesting stabilization of the protein. No difference, however, was observed between homozygous and heterozygous mice in the ability to develop cardiac hypertrophy in response to isoproterenol. The capacity to regenerate skeletal muscle was tested after cardiotoxin injection into the hind limbs of hetero- and homozygous mice. In activated satellite cells of both genotypes, rapid activation of Pop1-LacZ expression was observed. In heterozygous animals, LacZ activity was only transiently elevated in muscle precursor cells undergoing fusion and in newly formed myotubes. In homozygotes, persistence of LacZ expression and a retarded ability to regenerate skeletal muscle were apparent, suggesting that Pop1 plays a role in muscle regeneration.
Invasive properties of primary pediatric neoplasms in vitro.

Primary solid tumors were mechanically and/or enzymatically disassociated, and the resulting suspensions of single cells and small clumps of cells were seeded onto three different substrates, i.e., tissue culture plastic, rat smooth muscle cells (SMCs), and SMC-derived extracellular matrix. Tests of the relative effectiveness of these substrates in supporting the survival and/or growth of ten different neoplasms demonstrated that only two explants remained viable for longer than 2 weeks when seeded onto tissue culture plastic while nine of the ten survived on biological substrates for 1 month or longer. Thus, tissue culture plastic was a poor substrate for primary pediatric neoplasms. In general, more than 80% of the most common solid neoplasms in childhood (brain tumor, neuroblastoma, renal tumor, rhabdomyosarcoma, osteogenic sarcoma, and Ewing's sarcoma) routinely survived or grew in long-term cultures when cultured onto SMCs or their matrix. Both substrates were effective in promoting survival and/or growth; however, cells of neuroblastomas and certain brain tumors showed a preference for a living smooth muscle substrate. Tumor cells maintained their characteristic cellular and subcellular morphology when compared with the histology of the in vivo neoplastic lesions. Light and electron microscopy of selected neoplasms cultured on SMCs for various time periods demonstrated areas of distinct cellular invasion and/or partial destruction of the SMC multilayers which correlated with the invasive potentials of the neoplasms in patients. Invasion and destruction of the SMCs were also noticed with quiescent tumor cell cultures, indicating that growth was not a necessary property of invasion. Several neoplasms were also capable of the degradation of connective tissue proteins as indicated by the hydrolysis of radiolabeled SMC matrices, but simple correlations between the extent of matrix degradation and invasive ability could not be drawn. The culture system described consistently provided for the survival and/or growth of the most common pediatric tumors for long time periods. Thus, basic biological properties of primary tumors, e.g., growth, invasive potentials, and differentiation capabilities, could be investigated routinely.
Australian Election Study, 2007

SPSS Portable 2,594 KB; Stata v.8 2,516 KB; Stata v.7 2,510 KB; Nesstar Publisher 2,631 KB; NSDstat; DIF 2,646 KB; DBase 2,526 KB; Textfile 2,525 KB; Delimited 2,527 KB; SAS 2,561 KB; Comma Separated Value file 2,528 KB.
Improvement in degradability of 58s glass scaffolds by ZnO and β-TCP modification

ABSTRACT 58s bioactive glass shows great potential for bone defects repair. However, at early repairing stage, the degradation rate of 58s glass is too fast due to the fast ion-exchange. At later repairing stage, the degradation rate of 58s glass is too slow due to the high dense mineral layer. In this work, Zinc oxide (ZnO) and β-tricalcium phosphate (β-TCP) were introduced into 58s glass bone scaffolds to improve the degradability. The results showed that ZnO could decrease the degradation rate and promote the stability of 58s glass at early repairing stage. Moreover, the presence of β-TCP appeared to increase the degradation rate at a later stage of repairing. Furthermore, in vitro biocompatibility study, carried out using human osteoblast-like cells (MG63), demonstrated that ZnO and β-TCP enhanced cell attachment and proliferation. The study provided a reference for further research in bone tissue engineering.
Monoclonal antibodies against recombinant parts of the Ki‐67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave‐processed formalin‐fixed paraffin sections

The monoclonal antibody Ki‐67 reacts with a human nuclear cell proliferation‐associated antigen that is expressed in all active parts of the cell cycle. Recently we have raised monoclonal antibodies, MIB 1–3, against recombinant parts of the Ki‐67 antigen. These antibodies are true Ki‐67 equivalents, as demonstrated by immunostaining of fresh specimens, biochemistry, and molecular biological techniques. Formalin‐fixed, paraffin‐embedded sections routinely processed for immunohistochemistry failed to stain for Ki‐67 and MIB 2. Antibodies MIB 1 and MIB 3 labelled mitotic figures, while non‐mitotic proliferating cells were negative under these conditions. However, when dewaxed microwave oven‐ processed paraffin sections of formalin‐fixed tissues were used, MIB 1 and MIB 3 gave strong nuclear staining of those cells presumed to proliferate under a variety of normal and neoplastic conditions. Moreover, routine decalcification or depigmentation techniques did not alter the immunoreactivity of MIB I and MIB 3 with microwave‐processed paraffin sections. This method is highly reproducible, easy to perform at low cost, and no additional technical skill is needed because after microwave treatment just routine immunohistochemical methods are used. Since we have successfully applied this new method to sections obtained from paraffin blocks stored for a long time (in one case more than 60 years), the assessment of cell kinetics through the detection of Ki‐67 antigen is now possible on archival material collected in histopathology departments all over the world.
Diagnosis of stator winding turn to turn fault of induction motor using space vector pattern based on neural network

In this paper, first space vector model of symmetrical induction motor is extended to asymmetrical structure due to stator turn to turn fault. Then a novel scheme in order to diagnosis of this fault is proposed where a neural network with space vector pattern has used. In this scheme, new indexes using space vector properties of stator voltage and current, is defined that oscillation of this indexes is due to unbalancing of stator voltage and current. This scheme using suitable learning of neural network is able to recognize stator winding turn-fault regardless admissible unbalancing of the input voltage, balanced variation of three phase voltage, and admissible variation of load torque. Simulations were performed in Matlab/Simulink environment to validate the proposed method.
Placental lesions associated with maternal underperfusion are more frequent in early-onset than in late-onset preeclampsia

Abstract Objective: Preeclampsia (PE) has been classified into early- and late-onset disease. These two phenotypic variants of PE have been proposed to have a different pathophysiology. However, the gestational age cut-off to define “early” vs. “late” PE has varied among studies. The objective of this investigation was to determine the prevalence of lesions consistent with maternal underperfusion of the placenta in patients with PE as a function of gestational age. Study design: A nested case-control study of 8307 singleton pregnant women who deliver after 20 weeks of gestation was constructed based on a cohort. Cases were defined as those with PE (n=910); controls were pregnant women who did not have a hypertensive disorder in pregnancy (n=7397). The frequency of maternal underperfusion of the placenta (according to the criteria of the Society for Pediatric Pathology) was compared between the two groups. Logistic regression was used for analysis. Estimated relative risks (RRs) were calculated from odds ratios. Results: 1) The prevalence of lesions consistent with maternal underperfusion was higher in patients with PE than in the control group [43.3% vs. 15.9%, unadjusted odds ratio 4.0 (95% CI 3.5–4.7); P<0.001]; 2) the estimated RR of maternal underperfusion lesions in PE was higher than in the control group [RR=2.8 (95% CI 2.5–3.0)]; 3) the lower the gestational age at delivery, the higher the RR for these lesions; 4) early-onset PE, regardless of the gestational age used to define it (<32, 33, 34, 35 or 37 weeks) had a significantly higher frequency of placental lesions consistent with maternal underperfusion than late-onset PE (P<0.001 for all). Conclusions: 1) The earlier the gestational age of preeclampsia at delivery, the higher the frequency of placental lesions consistent with maternal underperfusion; 2) our data suggest that demonstrable placental involvement as determined by pathologic examination differs in early- and late-onset preeclampsia; and 3) this phenomenon appears to be a continuum, and we could not identify a clear and unambiguous gestational age at which lesions consistent with underperfusion would not be present.
Development of a German reading span test with dual task design for application in cognitive hearing research

Abstract Objective: To report the development of a standardized German version of a reading span test (RST) with a dual task design. Special attention was paid to psycholinguistic control of the test items and time-sensitive scoring. We aim to establish our RST version to use for determining an individual's working memory in the framework of hearing research in German contexts. Design: RST stimuli were controlled and pretested for psycholinguistic factors. The RST task was to read sentences, quickly determine their plausibility, and later recall certain words to determine a listener's individual reading span. RST results were correlated with outcomes of additional sentence-in-noise tests measured in an aided and an unaided listening condition, each at two reception thresholds. Study sample: Item plausibility was pre-determined by 28 native German participants. An additional 62 listeners (45–86 years, M = 69.8) with mild-to-moderate hearing loss were tested for speech intelligibility and reading span in a multicenter study. Results: The reading span test significantly correlated with speech intelligibility at both speech reception thresholds in the aided listening condition. Conclusion: Our German RST is standardized with respect to psycholinguistic construction principles of the stimuli, and is a cognitive correlate of intelligibility in a German matrix speech-in-noise test.
A Gene Gravity Model for the Evolution of Cancer Genomes: A Study of 3,000 Cancer Genomes across 9 Cancer Types

Cancer development and progression result from somatic evolution by an accumulation of genomic alterations. The effects of those alterations on the fitness of somatic cells lead to evolutionary adaptations such as increased cell proliferation, angiogenesis, and altered anticancer drug responses. However, there are few general mathematical models to quantitatively examine how perturbations of a single gene shape subsequent evolution of the cancer genome. In this study, we proposed the gene gravity model to study the evolution of cancer genomes by incorporating the genome-wide transcription and somatic mutation profiles of ~3,000 tumors across 9 cancer types from The Cancer Genome Atlas into a broad gene network. We found that somatic mutations of a cancer driver gene may drive cancer genome evolution by inducing mutations in other genes. This functional consequence is often generated by the combined effect of genetic and epigenetic (e.g., chromatin regulation) alterations. By quantifying cancer genome evolution using the gene gravity model, we identified six putative cancer genes (AHNAK, COL11A1, DDX3X, FAT4, STAG2, and SYNE1). The tumor genomes harboring the nonsynonymous somatic mutations in these genes had a higher mutation density at the genome level compared to the wild-type groups. Furthermore, we provided statistical evidence that hypermutation of cancer driver genes on inactive X chromosomes is a general feature in female cancer genomes. In summary, this study sheds light on the functional consequences and evolutionary characteristics of somatic mutations during tumorigenesis by propelling adaptive cancer genome evolution, which would provide new perspectives for cancer research and therapeutics.
Multilayered Socialization Processes in Transgenerational Family Firms

Building on an in-depth case study of a four-generational Scottish family firm, we generate a triple-layered model of socialization. Our findings go beyond the traditional focus on internal family socialization and value transmission and suggest that socialization involves three concentric layers unfolding over time, each with a distinct set of dimensions, values, challenges and processes: internal (transmitting knowledge within the family), interactive (resolving competing role demands through peer interactions), and experiential (interacting with both peer groups and malleable societal/economic frames). This novel theorization provides a promising framework for future research seeking to explain the complexities of socialization processes in transgenerational family firms.
Biochemical characterization and tissue distribution of human SULT2B1.

The human hydroxysteroid sulfotransferase (SULT) family is comprised of two subfamilies, SULT2A1 and SULT2B1. We characterized the substrate specificity, in vitro biochemical properties, and tissue distribution patterns of human SULT2B1a and SULT2B1b. In contrast to the wide substrate specificity of SULT2A1, SULT2B1a and SULT2B1b specifically catalyzed the sulfonation of 3beta-hydroxysteroids with high catalytic efficiency. Both SULT2B1 enzymes also sulfonated dihydrotestosterone. In vitro studies revealed that the biochemical properties of SULT2B1a and SULT2B1b were not significantly different from each other. However, tissue expression analysis suggested that they are differentially regulated. In contrast to the limited tissue distribution of SULT2A1, SULT2B1 was detected in a variety of hormone-responsive tissues including placenta, ovary, uterus, and prostate. The catalytic activity toward dehydroepiandrosterone and dihydrotestosterone, biologically important androgens, coupled with expression in prostate suggests that SULT2B1 may play a novel regulatory role that protects against the mitogenic effects of androgens.
Economics of upgrading gravel roads to Otta seal surface

ABSTRACT Maintenance of low volume roads especially gravel roads is costly, and millions of funding annually are spent for aggregate replacement alone. Otta seal, compared to other bituminous surface treatments (BSTs) for low volume roads that require high-quality materials and specialized expertise, can be constructed using cheaper local aggregates and accessible equipment. However, only three states have reported Otta seal constructions and performance in the US. In this study, an economic analysis was conducted to compare the cost of maintaining a gravel road to the cost of upgrading an existing gravel road to a double Otta seal surface. This analysis was conducted at three levels: deterministic life-cycle cost analysis (LCCA), a stochastic Monte Carlo simulation-based LCCA, and a traffic based economic analysis. A generic one-mile rural road in Midwest was considered as a case study location. Although, according to the analysis conducted in this paper, an upgrade to Otta seal investment might be justified by maintenance savings, resorting to only such justification cannot warrant investment in most cases. The upgrade from gravel road to Otta seal, or any other BSTs, might be justified in terms of enhancing safety for road users and also encouraging economic development beneficial to local areas.
Millimetre-wave broadband circularly polarized stacked microstrip antenna for satellite applications

A single-feed circularly polarized stacked square microstrip antenna is proposed for millimetre-wave satellite applications. The antenna consists of a square patch radiator with perturbation stubs along the diagonal direction and a stacked ring-slotted square patch. Designed on Rogers substrates with an overall size of 9.0 mm × 9.0 mm × 1.0 mm, the antenna exhibits the 10-dB return-loss bandwidth of 7.2 GHz (26.3 GHz–33.4 GHz) and 3-dB axial ratio (AR) bandwidth of 3.5 GHz (27.2 GHz–30.7 GHz). The boresight gain of the antenna is greater than 6.9 dBic across the 3-dB axial ratio bandwidth.
Glucose metabolism in cows fed low- and high-roughage diets.

Six lactating first-calf Holstein cows were used to test the effect of dietary roughage on glucose metabolism. Cows were fed either a low-roughage or high-roughage diet at isocaloric digestible energy intakes in a double changeover design experiment. Mean values (plus or minus standard deviation) for milk yield (kg/day), fat (%), lactose (%), and protein (%) for cows fed low-roughage were 19.0 plus or minus 4.4, 3.11 plus or minus . 78, 5.19 plus or minus . 27, 3.44 plus or minus . 48; values for cows fed high-roughage were 17.5 plus or minus 5.1, 3.99 plus or minus . 58, 4.94 plus or minus . 25, and 2.78 plus or minus . 33. One hour post-feeding on the 20th day of each period 2 mCi of tritiated glucose were administered to each cow by single injection to measure glucose kinetics. Mean values (plus or minus standard deviation) for plasma concentration (mg/100 ml) pool size (mg/kg), half-time (min), and utilization rate (mg/kg--75 per min) of glucose, and plasma insulin concentration (muU/ml) for cows fed low-roughage were 63.1 plus or minus 3.9, 17.9 plus or minus 3.4, 30.4 plus or minus 5.2, 8.55 plus or minus 2.44, and 22.0 plus or minus 3.9; for cows fed high-roughage values were 54.9 plus or minus 2.2, 114.5 plus or minus 17.2, 40.0 plus or minus 2.2, 4.06 plus or minus . 38, and 16.2 plus or minus 2.4. A glucose load was administered intravenously to each cow on the last day of each period. Glucose half-times and mean plasma insulin following the clearance test were not affected by diet. Compared to high-roughage, low-roughage diets greatly affect metabolism in lactating cows when isocaloric intakes of each are fed. Fat depression, however, may or may not occur simultaneously.