Miracle-dz/UniFAR-FTUs huggingface dataset:
Dissociable Human Perirhinal, Hippocampal, and Parahippocampal Roles during Verbal Encoding

The precise contribution of perirhinal cortex to human episodic memory is uncertain. Human intracranial recordings highlight a role in successful episodic memory encoding, but encoding-related perirhinal activation has not been observed with functional imaging. By adapting functional magnetic resonance imaging scanning parameters to maximize sensitivity to medial temporal lobe activity, we demonstrate that left perirhinal and hippocampal responses during word list encoding are greater for subsequently recalled than forgotten words. Although perirhinal responses predict memory for all words, successful encoding of initial words in a list, demonstrating a primacy effect, is associated with parahippocampal and anterior hippocampal activation. We conclude that perirhinal cortex and hippocampus participate in successful memory encoding. Encoding-related parahippocampal and anterior hippocampal responses for initial, remembered words most likely reflects enhanced attentional orienting to these positionally distinctive items.
A Probabilistic Energy Management Scheme for Renewable-Based Residential Energy Hubs

This paper proposes a new framework for home energy management (HEM) in the context of renewable-based residential energy hub using a probabilistic optimization approach. Different energy converters and storages, including combined heat and power, a plug-in hybrid electric vehicle, a heat storage unit, solar panels, and generic household appliances, are considered in the energy hub. The customer’s energy cost is considered as the objective of the HEM optimization problem and different operational limits of the energy hub components are modeled as the constraints. The two-point estimate method is incorporated in this paper to model the uncertainty associated with output power of the rooftop solar panels. Numerical results are provided to demonstrate the performance of the proposed approach.
Witch-Hunting at Crucible University: The Power and Peril of Competing Organizational Ideologies

The literature on organizational culture underscores the benefits of a strong culture—its capacity to draw people together through shared values and norms. Yet, the formation of a powerful ideology also has the capacity to promote divisiveness and to alienate those who fail to conform. This study employs Frank W. Lutz’s witch-hunting framework in order to examine an institutional crisis at a small private faith-based institution. The case provides a rich illustration of the potential dangers of divisive ideologies on campus.
Topical mometasone furoate for vulvar lichen sclerosus.

OBJECTIVE To assess the efficacy and safety of treating vulvar lichen sclerosus with mometasone furoate, a synthetic analogue of beclomethasone. STUDY DESIGN Thirty-one consecutive patients with biopsy-proven vulvar lichen sclerosus (LS) seen at the Florence Vulvar Clinic were entered into the study. Each subject's symptoms and the gross appearance of the lesions were recorded using a severity score according to the authors' previous studies. The patients were treated with a regimen of 0.1% mometasone furoate cream applications to the affected areas once daily for 4 weeks and then twice weekly for 8 weeks. After 12 weeks of treatment, the subjects were asked to rate the changes in their symptoms and were reevaluated by the same examiner for the gross appearance of the lesions. In every patient the before/after treatment total severity scores were compared using Wilcoxon's signed-rank test for statistical significance. RESULTS With mometasone furoate all the patients had a significant improvement (P < .001) in the gross aspects of the disease and a very dramatic decrease in symptoms (P < .001), with nearly all the subjects having complete symptomatic remission. Compliance was excellent, and no side effects were observed. CONCLUSION The improved risk/benefit ratio of mometasone furoate may minimize the possible long-term side effects expected when using a very potent topical steroid. Therefore, momentasone furoate cream may be an alternative to clobetasol propionate for treatment of vulvar LS, with similar efficacy but higher levels of safety and tolerability.
Controller parameter tuning based on neural network gradient

A wheeled mobile mechanism with a passive and/or active linkage mechanism for rough terrain environment is developed and evaluated. In our previous research, we developed a switching controller system for wheeled mobile robots in rough terrain. This system consists of two sub-systems: an environment recognition system using self-organizing map (SOM) and an adjustable control system using neural network. In this paper, we focus on the decision of controller parameters using hyperplane of adjusted neural network. Our proposed controller shows almost same performance of adjusted neural network controller in the experiments of the climbing over the stairs. And also, that controller shows better performance than well-tuned PID controller.
A hybrid Particle Swarm Evolutionary Algorithm for Constrained Multi-Objective Optimization

In this paper, a hybrid particle swarm evolutionary algorithm is proposed for solving constrained multi-objective optimization. Firstly, in order to keep some particles with smaller constraint violations, a threshold value is designed, the updating strategy of particles is revised based on the threshold value; then in order to keep some particles with smaller rank values, an infeasible elitist preservation strategy is proposed in order to make the infeasible elitists act as bridges connecting disconnected feasible regions. Secondly, in order to find a set of diverse and well-distributed Pareto-optimal solutions, a new crowding distance function is designed for bi-objective optimization problems. It can assign larger crowding distance function values not only for the particles located in the sparse region but also for the particles located near to the boundary of the Pareto front. In this step, the reference points are given, and the particles which are near to the reference points are kept no matter how crowded these points are. Thirdly, a new mutation operator with two phases is proposed. In the first phase, the total force is computed first, then it is used as a mutation direction, searching along this direction, better particles will be found. The comparative study shows the proposed algorithm can generate widely spread and uniformly distributed solutions on the entire Pareto front.
Expectation Propogation for Approximate Inference in Dynamic Bayesian Networks

We describe expectation propagation for approximate inference in dynamic Bayesian networks as a natural extension of Pearl's exact belief propagation. Expectation propagation is a greedy algorithm, converges in many practical cases, but not always. We derive a double-loop algorithm, guaranteed to converge to a local minimum of a Bethe free energy. Furthermore, we show that stable fixed points of (damped) expectation propagation correspond to local minima of this free energy, but that the converse need not be the case. We illustrate the algorithms by applying t,hem to switching linear dynamical systems and discuss implications for approximate inference in general Bayesian networks.
Parenting in poverty: Perspectives of high-risk parents

Parents considered high risk by child protection services commonly are striving to raise children in poverty but are identified as requiring improved parenting skills. Parent perceptions of their own needs are typically not sought or elicited. This longitudinal study of 35 parents over 18 months garnered 115 in-depth interviews focusing on parent views regarding barriers to effective parenting. Analysis indicated that parents uniformly identified poverty as the primary barrier to their capacity to provide adequate care for their children. Themes elicited indicated that financially parents were living precariously close to margins of defeat. Parents accepted personal responsibility for their economic and parental failings, equating no income with bad parenting. Depression and despair associated with poverty were acknowledged to impair parenting and increase self-doubt about parenting capacity. Experiences with social services generally led to low expectations of parenting assistance. The need for improved aid for impoverished parents is discussed.
What is a cool-core cluster? a detailed analysis of the cores of the X-ray flux-limited HIFLUGCS cluster sample

We use the largest complete sample of 64 galaxy clusters (HIghest X-ray FLUx Galaxy Cluster Sample) with available high-quality X-ray data from Chandra, and apply 16 cool-core diagnostics to them, some of them new. In order to identify the best parameter for characterizing cool-core clusters and quantify its relation to other parameters, we mainly use very high spatial resolution profiles of central gas density and temperature, and quantities derived from them. We also correlate optical properties of brightest cluster galaxies (BCGs) with X-ray properties. To segregate cool core and non-cool-core clusters, we find that central cooling time, t cool , is the best parameter for low redshift clusters with high quality data, and that cuspiness is the best parameter for high redshift clusters. 72% of clusters in our sample have a cool core (t cool 50 h ―1 71 kpc) projected separation between their BCG and X-ray peak. In contrast, only two of the 56 clusters with a small separation between the BCG and X-ray peak (<50 h ―1 71 kpc) show large-scale radio emission. Based on this result, we argue that a large projected separation between the BCG and the X-ray peak is a good indicator of a major merger. The properties of weak cool-core clusters as an intermediate class of objects are discussed. Finally we describe individual properties of all 64 clusters in the sample.
Online dating and mating: Perceptions of risk and health among online users

Abstract In this paper, we examine the behaviours and experiences of people who use online dating and how they may or may not address risk in their use of online dating. Fifteen people who used online dating took part in in-depth, online chat interviews. We found that online daters use a variety of methods for managing and understanding the risks they perceived to be associated with online dating. Online daters compared the risks of online dating with other activities in their lives to justify their use of the medium. Many felt self-confident in their personal ability to manage and limit any risks they might encounter and, for some, the ability to be able to scapegoat risk (that is to blame others) was a method by which they could contextualize their own experiences and support their own risk strategies. For many, the control offered by the online environment was central to risk management. Additionally, the social context in which an individual encountered a potential risk would shape how they perceived the risk and responded to it. People who use online dating do consider the risks involved and they demonstrate personal autonomy in their risk management. From a public health perspective, it is important to understand how risk is experienced from an individual perspective, but it is imperative that any interventions are implemented at a population level.
Paradoxes of proof and punishment: Psychological pitfalls in judicial decision making

Purpose. This study focuses on two psychological mechanisms that may inadvertently affect judges' decisions on proof of guilt and on punishment. It involves mechanisms that are clearly in conflict with formal judicial doctrine. One hypothesis, the conviction paradox, asserts that, faced with very serious offences, a judge's standard of proof will be lower than for less serious, but otherwise comparable, offences. A second hypothesis, compensatory punishment, asserts that in cases with relatively weak evidence, judges who nevertheless render a guilty verdict will be inclined to compensate their initial doubt on the matter of guilt by meting out a less severe sentence. Method. The hypotheses are evaluated in an experiment with Dutch judges and justices who serve in criminal courts. This was done using fictitious but highly realistic dossiers of criminal cases. Results. Neither of the two hypotheses was supported in the present study. Conclusions. Findings are discussed in relation to their implications for theory development and future research in the area of legal decision making. © 2007 The British Psychological Society.
Cooperation Theory and Organizations

Organizational researchers have largely ignored cooperation theory in their analyses of social interaction in organizations. Considerable experimental and field research by social and educational psychologists indicates the dynamics of cooperatively (positively), competitively (negatively), and individualistically (independently) linked goals and suggests their consequences on relationships and productivity. Results overall indicate that cooperation facilitates social interaction and productivity. However, studies done in organizational contexts with representative tasks are needed to generalize confidently to organizational practice. Organizational researchers can extend cooperation theory to understand the dynamics between superiors and subordinates and the relationships among departments. To make cooperation theory useful, knowledge is needed to identify conditions that affect how organizational members perceive their goal interdependence.
Altered expression and chromatin structure of the hippocampal IGF1r gene is associated with impaired hippocampal function in the adult IUGR male rat

Exposure to intrauterine growth restriction (IUGR) is an important risk factor for impaired learning and memory, particularly in males. Although the basis of IUGR-associated learning and memory dysfunction is unknown, potential molecular participants may be insulin-like growth factor 1 (Igf1) and its receptor, IGF1r. We hypothesized that transcript levels and protein abundance of Igf1 and IGF1r in the hippocampus, a brain region critical for learning and memory, would be lower in IUGR male rats than in age-matched male controls at birth (postnatal day 0, P0), at weaning (P21) and adulthood (P120). We also hypothesized that changes in messenger Ribonucleic acid (mRNA) transcript levels and protein abundance would be associated with specific histone marks in IUGR male rats. Lastly, we hypothesized that IUGR male rats would perform poorer on tests of hippocampal function at P120. IUGR was induced by bilateral ligation of the uterine arteries in pregnant dams at embryonic day 19 (term is 21 days). Hippocampal Igf1 mRNA transcript levels and protein abundance were unchanged in IUGR male rats at P0, P21 or P120. At P0 and P120, IGF1r expression was increased in IUGR male rats. At P21, IGF1r expression was decreased in IUGR male rats. Increased IGF1r expression was associated with more histone 3 lysine 4 dimethylation (H3K4Me2) in the promoter region. In addition, IUGR male rats performed poorer on intermediate-term spatial working memory testing at P120. We speculate that altered IGF1r expression in the hippocampus of IUGR male rats may play a role in learning and memory dysfunction later in life.
RC-Chain: a Simple Model of Delay with a Ramp Input

A simple semi-analytical model which allow to estimate the propagation delay of an RC-chain with a linear input is presented. The model has been extensively validated through circuit simulations. In particular, over 1000 different RC-chains were considered and simulated demonstrating the accuracy of the proposed model with respect to the most widely used Elmore delay metric.
Restructuring the Social Sciences: Reflections from Harvard's Institute for Quantitative Social Science

Abstract The social sciences are undergoing a dramatic transformation from studying problems to solving them; from making do with a small number of sparse data sets to analyzing increasing quantities of diverse, highly informative data; from isolated scholars toiling away on their own to larger scale, collaborative, interdisciplinary, lab-style research teams; and from a purely academic pursuit focused inward to having a major impact on public policy, commerce and industry, other academic fields, and some of the major problems that affect individuals and societies. In the midst of all this productive chaos, we have been building the Institute for Quantitative Social Science at Harvard, a new type of center intended to help foster and respond to these broader developments. We offer here some suggestions from our experiences for the increasing number of other universities that have begun to build similar institutions and for how we might work together to advance social science more generally.
Drosophila grim induces apoptosis in mammalian cells

Genetic studies have shown that grim is a central genetic switch of programmed cell death in Drosophila; however, homologous genes have not been described in other species, nor has its mechanism of action been defined. We show here that grim expression induces apoptosis in mouse fibroblasts. Cell death induced by grim in mammalian cells involves membrane blebbing, cytoplasmic loss and nuclear DNA fragmentation. Grim‐induced apoptosis is blocked by both natural and synthetic caspase inhibitors. We found that grim itself shows caspase‐dependent proteolytic processing of its C‐terminus in vitro. Grim‐induced death is antagonized by bcl‐2 in a dose‐dependent manner, and neither Fas signalling nor p53 are required for grim pro‐apoptotic activity. Grim protein localizes both in the cytosol and in the mitochondria of mouse fibroblasts, the latter location becoming predominant as apoptosis progresses. These results show that Drosophila grim induces death in mammalian cells by specifically acting on mitochondrial apoptotic pathways executed by endogenous caspases. These findings advance our knowledge of the mechanism by which grim induces apoptosis and show the conservation through evolution of this crucial programmed cell death pathway.
The cobalt(II) salt of the azo dye Orange G

Crystallizing the cobalt(II) salt of the azo dye Orange G from water was found to give the solvent-separated ion-pair species hexaaquacobalt(II) 7-oxo-8-(2-phenylhydrazin-1-ylidene)-7,8-dihydronaphthalene-1,3-disulfonate tetrahydrate, [Co(H2O)6](C16H10N2O7S2)·4H2O. The asymmetric unit of the cobalt(II) salt contains three independent octahedral [Co(OH2)6]2+ cations, three azo anions, all with similar configurations, and 12 uncoordinated water molecules. The structure is closely related to that of one of the known magnesium analogues. Both structures have Z′ = 3, feature nearly planar azo anions [maximum displacement of azo-N atoms from the plane of the phenyl ring = 0.058 (7) Å] in their hydrazone tautomeric form, form layer structures with hydrophilic and hydrophobic layers alternating along the b-axis direction, and are stabilized by an extensive network of hydrogen bonds.
Production and Regeneration of Lactobacillus casei Protoplasts

Methods for the production and regeneration of Lactobacillus casei protoplasts are described. Protoplasts of L. casei strains were obtained by treatment with mutanolysin or with mutanolysin and lysozyme together in a protoplast formation buffer containing 0.02 M HEPES (N-2-hydroxyethylpiperazine-N′-2-ethanesulfonic acid) (pH 7.0), 1 mM MgCl2, 0.5% gelatin, and 0.3 M raffinose. Cells were regenerated on a complex medium supplemented with bovine serum albumin, MgCl2, CaCl2, gelatin, and raffinose. Lengthy digestion with lytic enzymes inhibited the capacity of protoplasts to regenerate. The optimum conditions of protoplast formation varied from strain to strain. Using predetermined optimal conditions it was possible to prepare protoplasts of several L. casei strains and regenerate them with 10 to 40% efficiency. The methods were applicable to other species of lactobacilli as well.
Scalability of Redundancy Detection in Focused Document Collections

We describe the application of primarily symbolic methods to the task of detecting logical redundancies and inconsistencies between documents in a medium sized, domain focused collection (1000–40,000 documents). Initial investigations indicate good scalability prospects, especially for syntactic and semantic processing. The difficult and largely neglected task of mapping from linguistic/semantic representations to domain tailored knowledge representations is potentially more of a bottle-
A Longitudinal Study of Belief and Desire State Discourse During Mother–Child Play and Later False Belief Understanding

There is considerable interest in the role of mental state language in theory of mind development. This study examines cognitive and desire state discourse of 43 mothers during play interactions with their two-year-old children and theory of mind as indicated by a battery of false belief tasks around the age of five. Desire state comments of mothers during free play which were appropriate to the conversational context were significantly related to children's later theory of mind, and this relation was independent of other confounding variables, including a home-based measure of maternal sensitivity, and socio-economic status, and an estimate of child language. The child's desire state language was concurrently related to the mother's desire state language used appropriately, and the child's cognitive state language was related to the mother's appropriate cognitive state language. Although cognitive state language was not predictive of later theory of mind, this may be because this kind of language plays a later role in theory of mind development.
The first luminal loop confers insulin responsiveness to glucose transporter 4

Glucose transporter isoform 4 (GLUT4) is the sole glucose transporter responsible for the effect of insulin on postprandial blood glucose clearance. It is translocated to the plasma membrane by specialized insulin-responsive vesicles. Targeting of GLUT4 to these vesicles is mediated by sortilin, which interacts with the first luminal loop of the transporter.