Miracle-dz/UniFAR-FTUs huggingface dataset:
Safety , immunogenicity , and protective efficacy of two doses of RIX 4414 live attenuated human rotavirus vaccine in healthy Brazilian infants

Objective: To determine the safety, immunogenicity and efficacy of two doses of rotavirus vaccine in healthy Brazilian infants. Methods: A randomized, multicenter, double-blind, placebo-controlled trial was conducted in Brazil, Mexico and Venezuela. Infants received two oral doses of vaccine or placebo at 2 and 4 months of age, concurrently with routine immunizations, except for oral poliomyelitis vaccine (OPV). This paper reports results from Belém, Brazil, where the number of subjects per group and the viral vaccine titerswere: 194 (10 focus formingunits – FFU), 196 (10 FFU), 194 (10 FFU) and 194 (placebo). Anti-rotavirus (anti-RV) antibody responsewas assessed in 307 subjects. Clinical severity of gastroenteritis episodes was measured using a 20-point scoring system with a score of≥ 11 defined as severe GE. Results:The rates of solicitedgeneral symptomswere similar in vaccineandplacebo recipients. At 2monthsafter the second dose, a serum IgA response to RV occurred in 54.7 to 74.4% of vaccinees. No interference was seen in the immunogenicity of routine vaccines. Vaccine efficacy against any rotavirus gastroenteritis (RVGE) was 63.5% (95%CI 20.8-84.4) for the highest concentration (10 FFU). Efficacy was 81.5% (95%CI 44.5-95.4) against severe RVGE. At its highest concentration (10 FFU), RIX4414 provided 79.8% (95%CI 26.4-96.3) protection against severe RVGE by G9 strain. Conclusions: RIX4414 was highly immunogenic with a low reactogenicity profile and did not interfere with seroresponse to diptheria, tetanus, pertussis, hepatitis B and Hib antigens. Two doses of RIX4414 provided significant protection against severe GE caused by RV. J Pediatr (Rio J). 2007;83(3):217-224: Rotavirus, gastroenteritis, vaccine, efficacy. 1. Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde, Belém, PA, Brasil. Departamento de Pediatria, Universidade Federal do Pará (UFPA), Belém, PA, Brasil. 2. GlaxoSmithKline, Rio de Janeiro, RJ, Brasil. Professora adjunta, Instituto Carlos Chagas, Rio de Janeiro, RJ, Brasil. 3. Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde, Belém, PA, Brasil. Universidade do Estado do Pará (UEPA), Belém, PA, Brasil. 4. Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde, Belém, PA, Brasil. 5. GlaxoSmithKline, Rio de Janeiro, RJ, Brasil. 6. Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde, Belém, PA, Brasil. Secretaria Municipal de Saúde de Belém, Belém, PA, Brasil. 7. UEPA, Belém, PA, Brasil. Manuscript received Aug 1
Sensing in the Collaborative Internet of Things

We are entering a new era of computing technology, the era of Internet of Things (IoT). An important element for this popularization is the large use of off-the-shelf sensors. Most of those sensors will be deployed by different owners, generally common users, creating what we call the Collaborative IoT. This collaborative IoT helps to increase considerably the amount and availability of collected data for different purposes, creating new interesting opportunities, but also several challenges. For example, it is very challenging to search for and select a desired sensor or a group of sensors when there is no description about the provided sensed data or when it is imprecise. Given that, in this work we characterize the properties of the sensed data in the Internet of Things, mainly the sensed data contributed by several sources, including sensors from common users. We conclude that, in order to safely use data available in the IoT, we need a filtering process to increase the data reliability. In this direction, we propose a new simple and powerful approach that helps to select reliable sensors. We tested our method for different types of sensed data, and the results reveal the effectiveness in the correct selection of sensor data.
Spect (HMPAO) Support for Activation of the Medial Prefrontal Cortices during Toe Graphaesthesia

This experiment was designed to test the construct validity of psychometric analyses that suggested a strong functional association between the accuracy for toe graphaesthesia and selective activation of neurons within the medial prefrontal regions. Single Photon Emission Computerized Tomography (SPECT) profiles were obtained for three volunteers (2 men, 1 woman) after they had been exposed to a toe graphaesthesia task or had been exposed to the control setting. The two measurements for each participant were separated by at least one week. Qualitative evaluation, using criteria employed for clinical diagnoses, of serial coronal, sagittal, and horizontal sections clearly indicated a specific increase in uptake of tracer within the rostral one-third to one-half of the medial prefrontal cortices of all three subjects during the toe graphaesthesia task compared to that during baseline conditions. The results are consistent with our neuropsychological research which indicates that toe graphaesthesia may be an accurate and useful indicator of the functional integrity of the medial surfaces of the anterior cerebral hemispheres.
Whole Person Dementia Assessment

Although we can't currently offer a cure for Alzheimer's, we can provide better information and advice to people with the disease (and their caregivers) to help improve their ability to live and cope with this challenging disease. This groundbreaking book shows how to start making a difference during the initial evaluation and beyond. Treating every assessment as more than a simple diagnostic process, Whole Person Dementia Assessment sets the stage for more constructive interventions, better care, and a higher quality of life throughout the disease process by providing a richer understanding of the person and the way the disease is affecting him or her. Blending traditional clinical evaluation procedures with more person-centered approaches, Whole Person Dementia Assessment shows how to assess a person's cognitive deficits while also discovering and emphasizing remaining strengths and abilities. Best-practice assessment tools are recommended and provided, including a comprehensive, whole-person interview form. Backed by solid research findings, Dr. Benjamin T. Mast demonstrates that geriatricians, psychiatrists, psychologists, social workers, and long-term care providers who incorporate methods such as personal interviews, life review, and validation into their assessment processes, will substantially improve their ability to * develop rapport with the person and family members * collect more in-depth and valid assessment results * identify cognitive and behavioral strengths and weaknesses * recommend interventions With Whole Person Dementia Assessment, professionals who care about the well-being of their patients and residents can now provide more productive consultations that will result in better outcomes. Take advantage of this new opportunity to help lighten the burden of a devastating disease.
Do double ‘SS precursors’ mean double discontinuities?

SUMMARY Stacks of SS precursors have been widely used in the past two decades to investigate the existence and characteristics of upper mantle discontinuities on a global scale as well as in several regional cases. Here, we present observations of SS precursors from an Mb 6.7 earthquake recorded at the US Transportable Array in 2010. In this particular case, the S660S precursors on the transverse component are strong enough to be identified on individual seismograms across the array without any stacking procedures. Two S660S precursors are observed, seeming to suggest double discontinuities around 660 km depth in the bounce point region. Through careful analysis of 1-D and 3-D synthetic seismograms, we however discover that, although they have arrival times and slownesses that are very close to the theoretical values of SS precursors, the apparent ‘double precursors’ are artefacts because of mantle heterogeneity in the upper mantle near the receivers away from the bounce point region. This suggests that caution must be taken about appropriate azimuthal coverage at the SS bounce point, before interpreting double SS or PP precursors in terms of complex mineralogical transitions.
Neural responses to sounds presented on and off the beat of ecologically valid music

The tracking of rhythmic structure is a vital component of speech and music perception. It is known that sequences of identical sounds can give rise to the percept of alternating strong and weak sounds, and that this percept is linked to enhanced cortical and oscillatory responses. The neural correlates of the perception of rhythm elicited by ecologically valid, complex stimuli, however, remain unexplored. Here we report the effects of a stimulus' alignment with the beat on the brain's processing of sound. Human subjects listened to short popular music pieces while simultaneously hearing a target sound. Cortical and brainstem electrophysiological onset responses to the sound were enhanced when it was presented on the beat of the music, as opposed to shifted away from it. Moreover, the size of the effect of alignment with the beat on the cortical response correlated strongly with the ability to tap to a beat, suggesting that the ability to synchronize to the beat of simple isochronous stimuli and the ability to track the beat of complex, ecologically valid stimuli may rely on overlapping neural resources. These results suggest that the perception of musical rhythm may have robust effects on processing throughout the auditory system.
Biotransformation of a Textile AZO Dye Acid Yellow 25 by Marinobacter Gudaonensis AY-13

Biotransformation of Acid Yellow 25 was carried out using Marinobacter gudaonensis AY-13(Accession No. HE970768) isolated from natural marine environment. The decolorization of the azo dye Acid Yellow 25 in nutrient broth and half strength nutrient broth having 8.0% salt concentration was up to 92.00% and 90.03% respectively in 24 hours. The decolorization of the dye by cell-free extract was found to be upto 80.13 % in 24 hours. The decolorization of the dye was also studied in presence of different co-substrates viz. 1% glucose, 1% yeast extract and 1% starch and found that percent decolorization was up to 92.77%, 94.00% and 92.05% respectively. From these results it can be concluded that, the isolate could decolorize the dye very effectively. The percent COD reduction of the dye by the isolate was 70.00%. The degradation products formed were analyzed by GC-MS technique and it was found that culture degraded Acid Yellow 25 to the products having molecular weights 98, 70, 112, 125, 140, 168, 186, 128, 141, 83, 111, 154, 72 and 155. The microbial toxicity study revealed that degradation products of Acid Yellow 25 were non-toxic to ecologically important microorganisms like Pseudomonas sp. , Rhizobium sp. and Azotobacter sp.
Trends in tuberculosis.

One of the major medical advances of the 20th century has been the discovery of anti-tuberculosis drugs capable of curing almost every patient suffering from the disease. The application ofchemotherapy in technically advanced countries has resulted in a spectacular decline of tuberculosis. In contrast, in developing countries there has been little improvement since mass chemotherapy has failed because of lack of money, medical and paramedical personnel and inadequate health education. Trends in tuberculosis have been ones of success and failure, and changing epidemiology. Recent research and progress in tuberculosis has been concerned mainly with the design and application of chemotherapy programmes suitably adapted to the widely differing medical, financial and social needs of different communities.
Automatic Number Plate Recognition System for Vehicle Identification Using Optical Character Recognition

Automatic Number Plate Recognition (ANPR) is an image processing technology which uses number (license) plate to identify the vehicle. The objective is to design an efficient automatic authorized vehicle identification system by using the vehicle number plate. The system is implemented on the entrance for security control of a highly restricted area like military zones or area around top government offices e.g. Parliament, Supreme Court etc. The developed system first detects the vehicle and then captures the vehicle image. Vehicle number plate region is extracted using the image segmentation in an image. Optical character recognition technique is used for the character recognition. The resulting data is then used to compare with the records on a database so as to come up with the specific information like the vehicle’s owner, place of registration, address, etc. The system is implemented and simulated in Matlab, and it performance is tested on real image. It is observed from the experiment that the developed system successfully detects and recognize the vehicle number plate on real images.
UQeResearch: Semantic Textual Similarity Quantification

This paper presents an approach for estimating the Semantic Textual Similarity of full English sentences as specified in Shared Task 2 of SemEval-2015. The semantic similarity of sentence pairs is quantified from three perspectives - structural, syntactical, and semantic. The numerical representations of the derived similarity measures are then applied to train a regression ensemble. Although none of these three sets of measures is able to represent the semantic similarity of two sentences individually, our experimental results show that the combination of these features can precisely assess the semantic similarity of the sentences. In the English subtask our system’s best result ranked 35 among 73 system runs with 0.7189 average Pearson correlation over five test sets. This was 0.08 correlation points less than the best submitted run.
Changes in the deep subsurface microbial biosphere resulting from a field-scale CO2 geosequestration experiment

Subsurface microorganisms may respond to increased CO2 levels in ways that significantly affect pore fluid chemistry. Changes in CO2 concentration or speciation may result from the injection of supercritical CO2 (scCO2) into deep aquifers. Therefore, understanding subsurface microbial responses to scCO2, or unnaturally high levels of dissolved CO2, will help to evaluate the use of geosequestration to reduce atmospheric CO2 emissions. This study characterized microbial community changes at the 16S rRNA gene level during a scCO2 geosequestration experiment in the 1.4 km-deep Paaratte Formation of the Otway Basin, Australia. One hundred and fifty tons of mixed scCO2 and groundwater was pumped into the sandstone Paaratte aquifer over 4 days. A novel U-tube sampling system was used to obtain groundwater samples under in situ pressure conditions for geochemical analyses and DNA extraction. Decreases in pH and temperature of 2.6 log units and 5.8°C, respectively, were observed. Polyethylene glycols (PEGs) were detected in the groundwater prior to scCO2 injection and were interpreted as residual from drilling fluid used during the emplacement of the CO2 injection well. Changes in microbial community structure prior to scCO2 injection revealed a general shift from Firmicutes to Proteobacteria concurrent with the disappearance of PEGs. However, the scCO2 injection event, including changes in response to the associated variables (e.g., pH, temperature and salinity), resulted in increases in the relative abundances of Comamonadaceae and Sphingomonadaceae suggesting the potential for enhanced scCO2 tolerance of these groups. This study demonstrates a successful new in situ sampling approach for detecting microbial community changes associated with an scCO2 geosequestration event.
Mirror Principle I

Abstract. We propose and study the following Mirror Principle: certain sequences of multiplicative equivariant characteristic classes on Kontsevich’s stable map moduli spaces can be computed in terms of certain hypergeometric type classes. As applications, we compute the equivariant Euler classes of obstruction bundles induced by any concavex bundles – including any direct sum of line bundles – on P. This includes proving the formula of Candelas-de la Ossa-Green-Parkes hence completing the program of Candelas et al, Kontesevich, Manin, and Givental, to compute rigorously the instanton prepotential function for the quintic in P. We derive, among many other examples, the multiple cover formula for Gromov-Witten invariants of P, computed earlier by Morrison-Aspinwall and by Manin in different approaches. We also prove a formula for enumerating Euler classes which arise in the so-called local mirror symmetry for some noncompact CalabiYau manifolds. At the end we interprete an infinite dimensional transformation group, called the mirror group, acting on Euler data, as a certain duality group of the linear sigma model.
Breaking Barriers: Assistive Technology Tool as Educational Software to support Writing

The preliminary report by Siriraj Hospital suggested that 6% of population who are students in Thailand could be estimated to have learning disabilities. It is therefore necessary for our institute to develop suitable ICT technologies to assist the education of these learning disabilities children. We therefore developed a program called Thai Word Prediction Program. Thai Word Prediction program aims to assist students with learning disabilities in their writing. After the usability engineering, we conducted the experiment with students with learning disabilities at the School in Bangkok. Hence, the results indicated that all three students with learning disabilities in this study improved their ability of writing by 50%, 81.89% and 100% respectively.
Recent advances in cortical visual impairment

Cortical visual impairment (CVI) is the leading cause of bilateral visual impairment in children in Western countries. This finding reflects better methods for identifying visual impairment due to CNS injury and also advances in perinatal care, which have increased the survival rate of children with neurological morbidity. This review will describe advances in the diagnosis and management of CVI. Central to our discussion is a definition of CVI that includes a decrease in visual acuity. New treatment and rehabilitative measures are badly needed for this disorder. We hope to stimulate interest in CVI, a disease that has become a significant public health problem.
Breaking Cosmological Degeneracies in Galaxy Cluster Surveys with a Physical Model of Cluster Structure

It has been shown that in an idealized galaxy cluster survey, containing ≳10,000 clusters, statistical errors on dark energy and other cosmological parameters would be at the percent level. Furthermore, through ``self-calibration,'' parameters describing the mass-observable relation and cosmology could be simultaneously determined, although at a loss in accuracy by about an order of magnitude. Here we examine an alternative approach to self-calibration, in which a parameterized ab initio physical model is used to compute theoretical mass-observable relations from the cluster structure. As an example, we use a modified-entropy (``preheating'') model of the intracluster medium, with the history and magnitude of entropy injection as unknown input parameters. Using a Fisher matrix approach, we evaluate the expected simultaneous statistical errors on cosmological and cluster model parameters. We find that compared to a phenomenological parameterization of the mass-observable relation, our physical model yields significantly tighter constraints in both surveys and offers substantially improved synergy when the two surveys are combined. In a mock X-ray survey, we find statistical errors on the dark energy equation of state are a factor of 2 tighter than the phenomenological model, with Δw0 ~ 0.08 and its evolution, Δwa ≡ -Δdw/da ~ 0.23, with corresponding errors of Δw0 ~ 0.06 and Δwa ~ 0.17 from a mock Sunyaev-Zel'dovich (SZ) survey, both with Ncl ~ 2.2 × 104 clusters, while simultaneously constraining cluster model parameters to ≲10%. When the two surveys are combined, the constraints tighten to Δw0 ~ 0.03 and Δwa ~ 0.1, a 40% improvement over adding the individual experiment errors in quadrature and a factor of 2 improvement over the phenomenological model. This suggests that parameterized physical models of cluster structure would be useful when extracting cosmological constraints from SZ and X-ray cluster surveys.
Mainstreaming HIV / AIDS in the education systems in sub-Saharan Africa : some preliminary insights : HIV / AIDS and education

This article is based on a theoretical exploration of the concept of mainstreaming and actual experience of the African ministries of education in the region. The empirical part of the article is largely based on the initiative of the Association for the Development of Education in Africa (henceforth ADEA) on "Identifying Promising Approaches to HIVAIDS in Education in sub-Saharan Africa". The initiative was conceived in April 2001 and it is ongoing. The article examines the application of the concept of mainstreaming in education programming. It argues that even though there is tangible evidence of the process of mainstreaming HIV in education systems, there are still both theoretical or rather conceptual problems as well as problems related to implementation of programmes. Our purpose is exploratory since not all country case studies under the ADEA initiative have been completed. However, available data enable us to ask such fundamental questions as the following. Have the ministries of education managed to mainstream HIV / AIDS in their respective education systems? If so, how? Is the level or phase of mainstreaming reached by respective ministries sufficient? What are the problems facing the process of mainstreaming in the education sector? The rest of this paper seeks to answer these questions by focusing on the process of mainstreaming as attempted by various ministries of education that are participating in the ADEA initiative.
Imaging Words - Wording Image

The rapid growth of the Internet information sources has led to organizing proposals, such as the Semantic Web initiative, with its ontological level providing a formal structuring for this disparate data. But given the amount of information to be treated even in a restricted domain, manual organization becomes rapidly unmanageable, and automatic methodologies for ontology building are required. Here we describe techniques for the automatic construction of a image ontology based on multimedia data (text and images) for a specific class of objects, manmade tools. Our approach combines modification of existing lexical resources and search engine querying in order to obtain raw images. These images are then clustered into representative concepts for the ontology. Our automated approach can be applied to any subset of physical objects.