Miracle-dz/UniFAR-FTUs huggingface dataset:
Short-Term Effects of Combined High-Intensity Strength and Sprint Interval Training on Anthropometric Characteristics and Physical Performance of Elite Team Handball Players

Abstract Muscular strength and speed are critical physical factors in determining the technical and tactical skills of elite team handball players. This study thus investigated the effect of high-intensity muscular strength and sprint interval training (SIT) on lower limb explosive performance and anthropometric characteristics in 22 male handball athletes aged 20.2 ± 0.1 years. A training group (TG, n = 12) and a control group (CG, n = 10) were followed over 8 weeks parallel to regular handball training. The TG received combined additional high-intensity muscular strength and interval training twice per week during this period. The muscular training was comprised of 3 – 4 sets of 70 – 85 % of 1-RM (repetition maximum) of dynamic back half squat exercise; followed immediately by a short sprint program with 4, 5, and 6 maximal intensity repetitions of 30 m runs. Strength (1-RM of the half back-squat and bench press), first step (V1S), first 5 m (V5 m), squat jumps (SJ), counter movement jumps (CMJ) and the Modified Agility Test (MAT) were tested at the beginning and end of the study. Significant interaction effects (group × time) were observed for all parameters (η² range: 0.531 (MAT) to 0.829 (First 5 m)). All 10 parameters showed relevant intervention effects (d> 0.5) in the TG (highest intervention effect: CMJ: d = 4.05), the mean effect size being d = 1.85. In contrast, scores for the CG either remained unchanged or decreased (d = –0.24). We conclude that combined high-intensity strength and sprint interval training during the competitive season should be recommended to elite male handball players as a means of improving handball-related performance characteristics without compromising other critical aspects of the individual's performance.
The FCRL3 −169T>C polymorphism is associated with rheumatoid arthritis and shows suggestive evidence of involvement with juvenile idiopathic arthritis in a Scandinavian panel of autoimmune diseases

Background and objectives: The Fc receptor-like 3 (FCRL3) gene −169T>C single nucleotide polymorphism (SNP) has been reported to be associated with several autoimmune diseases (AIDs) in Japanese populations. However, association results in other populations have been conflicting. Therefore, we investigated this SNP in a Scandinavian panel of AIDs. Methods: We genotyped patients with rheumatoid arthritis (RA; n = 708), juvenile idiopathic arthritis (JIA; n = 524), systemic lupus erythaematosus (SLE; n = 166), ulcerative colitis (UC; n = 335), primary sclerosing cholangitis (PSC; n = 365), Crohn disease (CD; n = 149), a healthy control group (n = 1030) and 425 trio families with type 1 diabetes (T1D). Statistical analysis consisted of case–control and family-based association tests. Results: RA was associated with the C allele (odds ratio (OR) = 1.16, 95% CI 1.01 to 1.33) and the CC genotype (OR = 1.30, 95% CI 1.01 to 1.67) of the FCRL3 −169T>C SNP in our material. Suggestive evidence for association was also found for JIA (CC genotype: OR = 1.30, 95% CI 0.99 to 1.70), and clinical subgroup analysis indicated that this was connected to the polyarticular subgroup. No significant association was found with SLE, UC, CD, PSC or T1D. In patients with RA, we found no significant interaction between the FCRL3 −169T>C and PTPN22 1858C>T SNPs, nor between the FCRL3 −169CC genotype and IgM-rheumatoid factor or anti-cyclic citrullinated peptide titre levels. Conclusion: We found an association between the FCRL3 −169T>C SNP and RA, and suggestive evidence for involvement with JIA, in a Norwegian population. These findings lend support for a role for this SNP in RA across ethnically diverse populations, and warrant follow-up studies in JIA.
Commande optimale de l'alterno démarreur avec prise en compte de la saturation magnétique

Nous avons presente dans ce memoire une methodologie d'optimisation des lois de commande d'un alterno demarreur asynchrone. Cet outil permet de rechercher d'une part le meilleur reglage des grandeurs de commande (tension et glissement) en regime stationnaire dans les deux modes de fonctionnement combines de l'ADI, compte tenu des objectifs a atteindre et des contraintes de l'application. D'autre part, il permet de rechercher l'espace de fonctionnement maximal de la machine, c'est a dire le couple ou la puissance en fonction de la vitesse, respectivement en mode demarreur et alternateur. Le mode d'alimentation sinusoidal est privilegie, mais le fonctionnement en surmodulation est aussi envisage a forte vitesse, pour imposer le flux optimal lorsque la limitation en tension du reseau de bord est atteinte. Pour garantir la robustesse de la commande, une methode d'identification hors ligne tenant compte de la saturation magnetique y est presentee.
Structural aspects of skeletal keratan sulphates.

9. Wiedemann, H. , Paulsson, M. , Timpl, R. , Engel, J. & Heinegard, D. ( 1 984) Biochem. J . 224.3 1 1-333 10. Miirgelin, M. , Paulsson, M. , Hardingham, T. , Heinegard, D. & Engel. J. ( 1988) Biochern. J . 253, 175-1 85 I I. Fosang. A. & Hardingham, T, (1989) Biochern. J. 261, 801-809 12. Paulsson, M. , Morgelin, M. , Wiedemann, H. , Beardmore-Gray, M. , Dunham, D. , Hardingham, T. , Heinegard, D. , Timpl, R. & Engel, J. ( 1 987) Biochem. J . 245,763-772 13. Halberg, D. , Proulx, G. , Doege, K. , Yamada, Y. & Drickamer, K. (1 988) J . Hiol. C'hem. 263,9486-9490 14. Heinegard, D. , Bjiirne-Person. A,, Ciister, L. Franzen, A,, Gardell, S. , Malmstriim, A. , Paulsson, M. , Sandfalk. R. & Vogel, K. ( 1 985) Biochem. J . 230, 18 I I94 243,255-259
A novel switched-capacitor capacitance-to-digital converter for single element capacitive sensors

A capacitance-to-digital converter (CDC) that gives a digital value proportional to the change in the capacitance of a sensor, independent of its nominal capacitance, is presented in this paper. The CDC presented is suitable for single element capacitive sensors. For most of the CDCs, available in the market, the output depends on the nominal value of the sensor. Thus, a manual intervention for appropriate correction in the output is required whenever a new sensor is connected to such CDCs. The proposed CDC uses a simple automatic calibration, employing a digitally controlled reference voltage in a feedback topology, and provides an output independent of the nominal value of the sensor employed. This automatic calibration also removes the dependence on the accuracy of the absolute value of reference capacitor, in the final output. The proposed CDC is based on a switched-capacitor dual-slope technique and possesses the advantages of the dual-slope conversion method. A prototype CDC has been developed and the test results are presented. The results obtained show that the output of the proposed converter is not a function of the nominal capacitance of the sensor for a wide range (50 pF to 1.15 nF). For this range, the worst error noted from the prototype CDC was less than 0.65 %.
Educational achievements in Pierre Robin Sequence

Abstract The aim of this retrospective population-based study was to determine if there is any significant difference in academic achievement between students with a Pierre Robin Sequence (PRS) compared with the general population of Swedish students at the typical time of graduation from compulsory school (usually at 16 years of age). The data were obtained from the Swedish Medical Birth Register for the years 1973–1986 and linked to the Swedish School-Grade Register, which generated a data set of 68 individuals with PRS that were compared with a control group consisting of 1,249,404 individuals. The following outcomes were measured: not receiving a school leaving certificate; their odds of receiving lowest grade; and reduced odds of receiving high grade in the following subjects: mathematics; English; Swedish; and physical education, and their grade point average. For the control group 2.74% did not receive their leaving certificate, while for the individuals with PRS 9.68% (OR = 4.00; 95% CI = 1.81–8.86) did not receive their leaving certificate. There were no differences between the groups in mathematics, English, and Swedish, while, in physical education, individuals with PRS had significantly reduced odds of receiving a high grade in the relative grading system. Individuals with PRS had a significantly lower grade point average: 3.00 ± 0.09 in comparison to the control group: 3.23 ± 0.002, p = 0.002. This study indicates that individuals with PRS experience significant difficulties in their educational achievements in compulsory school in Sweden.
Conservation Priorities for Russian Mammals

It will be increasingly important, especially in Russia, to identify way to prioritize use of limited rresources for conservation efforts. Considering threatened species in the context of the whole fauna suggests the concept of "chance of listing" in the internationally established "Red List", and poses the question of how it is related to species' life history traits. L. Polishchuk in this Policy Forum shows that for Russian mammals chance of listing is most closely associated with annual fecundity. A focus on the subset of mammalian species whose fecundity is lower than 2.9 daughters per year should be the particular concern of the conservationist and would cause a shift in current policies.
Endocytosis and vacuolar degradation of the plasma membrane-localized Pdr5 ATP-binding cassette multidrug transporter in Saccharomyces cerevisiae

Multidrug resistance (MDR) to different cytotoxic compounds in the yeast Saccharomyces cerevisiae can arise from overexpression of the Pdr5 (Sts1, Ydr1, or Lem1) ATP-binding cassette (ABC) multidrug transporter. We have raised polyclonal antibodies recognizing the yeast Pdr5 ABC transporter to study its biogenesis and to analyze the molecular mechanisms underlying MDR development. Subcellular fractionation and indirect immunofluorescence experiments showed that Pdr5 is localized in the plasma membrane. In addition, pulse-chase radiolabeling of cells and immunoprecipitation indicated that Pdr5 is a short-lived membrane protein with a half-life of about 60 to 90 min. A dramatic metabolic stabilization of Pdr5 was observed in delta pep4 mutant cells defective in vacuolar proteinases, and indirect immunofluorescence showed that Pdr5 accumulates in vacuoles of stationary-phase delta pep4 mutant cells, demonstrating that Pdr5 turnover requires vacuolar proteolysis. However, Pdr5 turnover does not require a functional proteasome, since the half-life of Pdr5 was unaffected in either pre1-1 or pre1-1 pre2-1 mutants defective in the multicatalytic cytoplasmic proteasome that is essential for cytoplasmic protein degradation. Immunofluorescence analysis revealed that vacuolar delivery of Pdr5 is blocked in conditional end4 endocytosis mutants at the restrictive temperature, showing that endocytosis delivers Pdr5 from the plasma membrane to the vacuole.
A new approach for attitude estimation of unicycle robot

Attitude Estimation is critical for balance control of Unicycle Robot, Accelerometers and gyroscopes are always used for posture detecting, and unscented Kalman filter(UKF) is adopted as sensors information fusion algorithm. Because the accelerometer is sensitive to external vibration and non-gravitational acceleration, the results of attitude estimation are extremely inaccurate. In order to overcome this problem, through the deeply analysis to Kalman filter algorithm and coupled with a strong validation of experimental results, this paper proposes a new approach based on the UKF algorithm. The new algorithm compensates the external acceleration errors by adjusting the measurement noise covariance adaptively. The experimental results show that the extended unscented Kalman filter algorithm has a good effect for solving unicycle robot posture detecting problems and eventually gets the more accurate attitude angles.
A Chatbot as a Natural Web Interface to Arabic Web QA

In this paper, we describe a way to access Arabic Web Question Answering (QA) corpus using a chatbot, without the need for sophisticated natural language processing or logical inference. Any Natural Language (NL) interface to Question Answer (QA) system is constrained to reply with the given answers, so there is no need for NL generation to recreate well-formed answers, or for deep analysis or logical inference to map user input questions onto this logical ontology; simple (but large) set of pattern-template matching rules will suffice. In previous research, this approach works properly with English and other European languages. In this paper, we try to see how the same chatbot will react in terms of Arabic Web QA corpus. Initial results shows that 93% of answers were correct, but because of a lot of characteristics related to Arabic language, changing Arabic questions into other forms may lead to no answers.
A Proposal of Location Estimation with Maximum likelihood Function using Joint PDF of Received Signals and prior Measured Signals

A novel location estimation with maximum log-likelihood function using joint probability function (PDF) of received signals and prior measured signals is proposed in order to improve the accuracy of the location estimation of mobile station (MS). We assume a spatial correlation between the received signals and the prior measured signals in the vicinity of the measured points. Using Bayesian theorem, a log-likelihood function is derived based on a new conditional PDF associated with a correlation. Computer simulation is carried out to clarify the improvement of the accuracy of the location estimation. It is shown that the estimation accuracy is improved by 25.4% with 16 prior measured points in 200 square meters as compared with that in case of conventional method
Photoconductive imaging in a photon scanning tunnelling microscope capable of point‐contact current sensing using a conductive fibre probe

A photoconductive photon scanning tunnelling microscope was developed to investigate the point‐contact photoconductive properties of condensed matter. In order to detect the current and the optical signal at a local point on a surface, we coated the edge of a bent type fibre probe with indium tin oxide. Thus it was possible to measure both photocurrent and optical property with subwavelength resolution. The performance of the novel microscope was evaluated by analysing an organic thin film of copper phthalocyanine (CuPc), which is known to be an efficient photoconductive material. Photocurrent and current–voltage characteristics were observed at the local point on the CuPc thin films. Furthermore, photoconductive images were obtained with topography and near‐field optical imaging using this system. The photoconductive PSTM shows potential in various areas of future optics and electronics.
Customer expectations and moderating role of demographics in fresh food retail

PurposeThe purpose of this paper is to identify the dimensions of customer expectations and study the moderating role of demographics in the context of fresh food retail.Design/methodology/approachA structured questionnaire was designed using extant literature review followed by expert opinions. The survey was conducted among the customers in the twin cities of Maharashtra in India. The factors of customer expectations were identified using exploratory factor analysis (EFA) and further confirmed using confirmatory factor analysis in SPSS and AMOS, respectively. The significance of the customer expectations on customer satisfaction was studied using structural equation modeling. Subsequently, the role of demographics was studied using two-step cluster analysis and multigroup moderation.FindingsDuring EFA three factors emerged, namely, product-related features, in-store quality and store support services. Structural model evaluation found product-related features and in-store quality significantly influencing the customer satisfaction, while store support services were found as a non-significant factor in the region studied. Further, using cluster analysis customers were segregated into three groups, namely, traditional, autonomous and premium customers, where the premium customers were found to prefer the store support services on a higher scale, and similar results were obtained using multigroup moderation. Demographics, namely, gender, age, respondents’ income and marital status moderated for product-related features and in-store quality. Interestingly, respondents’ income also moderated for the store support services.Practical implicationsThe findings provide directions for store managers of the fresh food category to align supply chain decisions with the unique requirements of customers considering their socio-economic characteristics.Originality/valueOn the basis of social exchange theory, the authors found that in a mutually beneficial relationship, concerning the value proposition, retailers need to address the requirement of the different income group customers for store support services.
[Obsessive-compulsive disorder with psychotic features: psychopathological and personological aspects].

AIM The aims of this study are to analyze psychopathological relations between obsessive-compulsive and psychotic symptoms in a group of patients with obsessive-compulsive disorder (OCD), and to verify if the obsessive subgroup with psychotic features can be considered as a distinct OCD subtype. METHODS The study sample included 68 patients with OCD who were divided into two different groups (OCD with and without psychotic features). All subjects completed the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), the Scale for the Assessment of Positive Symptoms (SAPS), the Hamilton Depression Rating Scale (HDRS), and the Structured Interview for DSM-IV Personality Disorders (SIDP-IV). RESULT Twenty subjects (29.4%) were affected by OCD with psychotic features. They were characterized by an earlier onset of obsessive illness (p<0.05), a more frequently chronic course (p<0.01), an "atypical" obsessive-compulsive symptomatology (with poor insight and anxiety) (p<0.001), higher levels of depression (p<0.05), and a higher prevalence of schizotypal personality disorder (p<0.01). DISCUSSION Patients affected by OCD with psychotic symptoms appear to be a distinct subtype of obsessive-compulsive disorder, characterized by a set of specific psychopathological and personological features. However, the finding that these subjects have a higher prevalence of schizotypal personality disorder seems to suggest that they can be considered as a peculiar clinical subset belonging to the schizophrenia-spectrum disorders rather than a group of obsessive individuals placed on the most serious clinical extreme of the OCD spectrum.
Dissociation of Inositol-requiring Enzyme (IRE1α)-mediated c-Jun N-terminal Kinase Activation from Hepatic Insulin Resistance in Conditional X-box-binding Protein-1 (XBP1) Knock-out Mice*

Background: Endoplasmic reticulum (ER) stress has been implicated in causing hepatic insulin resistance. Results: Fructose-fed XBP1 knock-out mice were protected from hepatic insulin resistance despite increased hepatic ER stress and JNK activation. Conclusion: ER stress and hepatic JNK activation can be disassociated from hepatic insulin resistance. Significance: Hepatic ER stress is not a direct causal factor in hepatic insulin resistance. Hepatic insulin resistance has been attributed to both increased endoplasmic reticulum (ER) stress and accumulation of intracellular lipids, specifically diacylglycerol (DAG). The ER stress response protein, X-box-binding protein-1 (XBP1), was recently shown to regulate hepatic lipogenesis, suggesting that hepatic insulin resistance in models of ER stress may result from defective lipid storage, as opposed to ER-specific stress signals. Studies were designed to dissociate liver lipid accumulation and activation of ER stress signaling pathways, which would allow us to delineate the individual contributions of ER stress and hepatic lipid content to the pathogenesis of hepatic insulin resistance. Conditional XBP1 knock-out (XBP1Δ) and control mice were fed fructose chow for 1 week. Determinants of whole-body energy balance, weight, and composition were determined. Hepatic lipids including triglyceride, DAGs, and ceramide were measured, alongside markers of ER stress. Whole-body and tissue-specific insulin sensitivity were determined by hyperinsulinemic-euglycemic clamp studies. Hepatic ER stress signaling was increased in fructose chow-fed XBP1Δ mice as reflected by increased phosphorylated eIF2α, HSPA5 mRNA, and a 2-fold increase in hepatic JNK activity. Despite JNK activation, XBP1Δ displayed increased hepatic insulin sensitivity during hyperinsulinemic-euglycemic clamp studies, which was associated with increased insulin-stimulated IRS2 tyrosine phosphorylation, reduced hepatic DAG content, and reduced PKCϵ activity. These studies demonstrate that ER stress and IRE1α-mediated JNK activation can be disassociated from hepatic insulin resistance and support the hypothesis that hepatic insulin resistance in models of ER stress may be secondary to ER stress modulation of hepatic lipogenesis.
Probabilistic robust design with linear quadratic regulators

In this paper, we study robust design of uncertain systems in a probabilistic setting by means of linear quadratic regulators. We consider systems affected by random bounded nonlinear uncertainty so that classical optimization methods based on linear matrix inequalities cannot be used without conservatism. The approach followed here is a blend of randomization techniques for the uncertainty together with convex optimization for the controller parameters. In particular, we propose an iterative algorithm for designing a controller which is based upon subgradient iterations. At each step of the sequence, we first generate a random sample and then we make a subgradient step for a convex constraint defined by the LQR problem. The main result of the paper is to prove that this iterative algorithm provides a controller which quadratically stabilizes the uncertain system with probability one in a finite number of steps. In addition, at a fixed step, we compute a lower bound of the probability that a quadratically stabilizing controller is found.
Investigating the persuasive impact and underlying processes of interactive magazine ads in a real-life setting

ABSTRACT This study tests a theoretical framework to explain the persuasive impact of interactive magazine ads on consumers’ ad and brand attitudes. To obtain realistic (unforced) responses, a field experiment was conducted with a one-factor (interactive vs. non-interactive magazine ad) between-subjects design (N = 98). Results showed that, although they rarely used it, participants positively evaluated the presence of an interactive feature in a digital magazine ad. Furthermore, parallel-mediation analyses revealed that the interactive magazine ad was perceived as more interactive and more surprising than the non-interactive ad, which ultimately positively impacted consumers’ attitudes towards the magazine. A second real-life setting experiment (N = 121) confirmed and extended these findings by revealing that the mediation effects were even stronger when consumers had used the interactive feature (vs. only seen). In addition, the relationship between interactive magazine ads and consumers’ attitudinal responses was explained slightly better by ‘perceived surprise’ than by ‘perceived interactivity. ’