Miracle-dz/UniFAR-FTUs huggingface dataset:
Alternative Hypotheses of Hybrid Vigor.

YBRID vigor has been observed for centuries but explanations in terms H of Mendelian heredity have, of course, been formulated only recently. The word heterosis was proposed by SHULL (1914) for this increase in vigor following the union of dissimilar gametes and has come into general use. SHULL (1908, 1911) and EAST (1908) believed that there exists a stimulus on crossing due to the genetic difference in the two germ plasms which would increase with the amount of difference. The alternative dominance hypothesis, first stated explicitly by BRUCE (1910) and KEEBLE and PELLEW (1910), has come to be widely accepted. This idea depends on the observation that there is a positive correlation between recessiveness and detrimental effect (or dominance and beneficial effect). According to this hypothesis some of the detrimental recessives brought into the hybrid zygote by one parent are rendered ineffective by their dominant alleles from the other. The result is an increase in vigor of the hybrid as compared with the parent stocks. Early objections to the theory were largely removed when JONES (1917) showed that with linkage and COLLINS (1921) showed that with a large number of factors, even in the absence of linkage, the consequences of the dominance hypothesis and the stimulation of heterozygosis hypothesis of EAST and SHULL were very similar and could not be distinguished in practice. The purpose of this inquiry is to determine the maximum vigor that might occur under the conditions implied by the dominance hypothesis and to see if this theory provides an adequate explanation for observed increases in vigor on hybridization.
3D human action recognition in multiple view scenarios

This paper presents a novel view-independent approach to the recognition of human gestures of several people in low resolution sequences from multiple calibrated cameras. In contraposition with other multi-ocular gesture recognition systems based on generating a classification on a fusion of features coming from different views, our system performs a data fusion (3D representation of the scene) and then a feature extraction and classification. Motion descriptors introduced by Bobick et al. for 2D data are extended to 3D and a set of features based on 3D invariant statistical moments are computed. Finally, a Bayesian classifier is employed to perform recognition over a small set of actions. Results are provided showing the effectiveness of the proposed algorithm in a SmartRoom scenario.
Short-Chain Aliphatic Polysulfonates Inhibit the Entry of Plasmodium into Red Blood Cells

ABSTRACT Several steps in the pathogenesis of a Plasmodium falciparum infection depend on interactions of parasite surface proteins with negatively charged sugars on the surface of host cells such as sialate residues or glycosaminoglycans. For these reasons, our previous studies examining agents that interfere with heparan sulfate-protein binding during amyloidogenesis suggested that short-chain aliphatic polysulfonates may prove useful as antimalarial agents. A series of related polysulfonates were synthesized and assessed both in tissue culture with the asexual stages of P. falciparum in human red blood cells and in vivo by use of Plasmodium berghei infections in mice. Poly(vinylsulfonate sodium salt) (molecular weight range, 1,500 to 3,000) proved effective in interfering with P. falciparum merozoite entry into human red blood cells and significantly delaying the increase in the level of P. berghei parasitemia in mice. The concept that anionic molecules that mimic large polysaccharide structures may have antimalarial properties has been suggested and examined previously. Our results suggest that related anionic agents [poly(vinylsulfonate sodium salt)-like molecules] orders of magnitude smaller than those previously considered may prove useful in abrogating merozoite entry into erythrocytes and may potentially block sporozoite entry into liver cells. Structure-activity studies conducted to enhance these properties may provide compounds with scope for significant further analysis and development.
Does less autonomy erode women's health? Yes. No. Maybe

Understanding the determinants of health is a central objective of human biology and related fields. Female autonomy is hypothesized to be an important determinant of women's health as well as demographic outcomes. The literature relating women's health to their everyday autonomy has produced conflicting results, and this may be due in part to the application of different measures of autonomy and different measures of health. Using secondary data from a large nationally representative study, this study examines the relationship between multiple measures of female autonomy and three measures of wellbeing among women living in Uzbekistan (n = 5,396). The multivariate results show that women's autonomy related to freedom of movement is associated with lower levels of depression symptomatology and lower systolic blood pressure. Respondents who assert that women should have control over their bodies also had lower odds of high depression symptoms and lower diastolic blood pressure. In contrast, women with greater decision‐making autonomy were more likely to be classified as having high depressive symptomatology and higher diastolic blood pressure. Building on recent work, we suggest that these associations might reflect varying levels of agreement between men and women, and we provide some limited evidence to support this. This study stands as a theoretical and methodological cautionary note by suggesting that the relationship between autonomy and health is complex. Further, if differences in gender agreement underlie differences in the predictive accuracy of autonomy scales, then human biology researchers will need to begin collecting identical data from men and women. Am. J. Hum. Biol. 2010. © 2009 Wiley‐Liss, Inc.
Marketing (as) rhetoric: an introduction

This special section of the Journal of Marketing Management is dedicated to the exploration of the relationship between the relatively modern discipline of marketing and the ancient subject of rhetoric. While there is a small but significant tradition of using rhetorical perspectives to analyse and investigate aspects of marketing theory and practice, our title suggests that rhetoric can be identified with marketing at a more fundamental level. Indeed, Tonks’ (2002, p. 803) insistence, in this very journal, that rhetoric ‘as a framing device and as an instrument for managerial action is central to a full appreciation of marketing reality’ has acted as our mission statement in putting together both this special section and the First International Symposium on Marketing (as) Rhetoric that preceded it in 2017 at Bournemouth University. Before introducing the invited contributions and the peer-reviewed articles that make up this special section, we wish to outline for the journal readership the basic arguments for treating marketing as a form, or an instantiation, of rhetoric. This must inevitably involve a certain degree of engagement with the history of rhetoric but this is important precisely because most marketing scholars are generally not familiar with this history, and therefore fall prey to the pejorative usage of the term to signify ‘empty’ discourse designed to manipulate or trick.
Regulation of Sam68 activity by small heat shock protein 22

Sam68 associates with c‐Src kinase during mitosis. We previously demonstrated that Sam68 functionally replaces and/or synergizes with HIV‐1 Rev in rev response element (RRE)‐mediated gene expression and virus production. Furthermore, we reported that knockdown of Sam68 inhibited Rev‐mediated RNA export and it is absolutely required for HIV‐1 production. In the present study, we identified small heat shock protein, hsp22, as a novel interacting partner of Sam68. Hsp22 binds to Sam68 in vitro and in vivo. Overexpression of hsp22 significantly inhibits Sam68‐mediated RRE‐ as well as CTE (constitutive transport element)‐dependent reporter gene expression. Furthermore, exposing 293T cells to heat shock inhibits Sam68/RRE function by virtue of elevating hsp22. The critical domain of hsp22 that interacts with Sam68 resides between amino acids 62 and 133. Our studies provide evidence for the first time that hsp22 specifically binds to Sam68 and modulates its activity, thus playing a role in the post‐transcriptional regulation of gene expression. J. Cell. Biochem. 99: 1353–1362, 2006. © 2006 Wiley‐Liss, Inc.
Cholesterol: a dark horse in signalling race.

DOI:10.1097/MOL.0000000000000435 The role of cellular lipids in the old biochemistry textbooks was stipulated as either structural, to create membranes and compartmentalize the cell, or as a source of energy, to be consumed. Most lipids grew out of these definitions and lipid-mediated signalling is a fast developing field of biochemistry. Cholesterol was left behind in this regard – but no more. Cholesterol was implicated in signalling events before, but mainly in a permissive role, through changing properties of the membranes holding receptors. Cholesterol is an essential component and regulator of lipid rafts, a key hub for signalling and endocytic events on the plasma membrane [1]. Cholesterol also controls properties of the endoplasmic reticulum membrane, triggering regulatory cascade leading to release of SREBPs. Recent discoveries, however, revealed that cholesterol also has a direct role as a signalling molecule. Two almost simultaneously published very elegant studies demonstrated that cholesterol in a dose-dependent manner specifically binds to, and induces conformational change of, Smoothened (SMO), a key protein in Hedgehog signalling pathway [2 && ,3 && ]. Binding of cholesterol to SMO induced downstream signalling events ending up in transcriptional activation of Hedgehog-responsive genes followed by cell differentiation responses almost identical to those observed with Sonic Hedgehog stimulation. These findings demonstrated for the first time that cholesterol may function as a bona fide specific ligand instead of just creating environment favouring signalling from various receptors. Interestingly, both studies established that cholesterol binds to the cysteine-rich domain of SMO, which is located at the extracellular part of the protein. This implies that regulatory pool of cholesterol is not intracellular and not even plasma membrane cholesterol pools, but must be extracellular cholesterol. Very little of unbound soluble cholesterol can be found extracellularly, necessitating an involvement of either a lipoprotein or a cellular cholesterol transporter, such as ATP binding cassette transporter A1 (ABCA1), that would transfer plasma membrane cholesterol to the extracellular domain of SMO. The Hedgehog signalling pathways have well established role in embryogenesis and in pathogenesis of cancer, with involvement of these pathways into development of atherosclerosis and cardiometabolic diseases only
A comprehensive study of classification techniques for sarcasm detection on textual data

During the last decade majority of research has been carried out in the area of sentiment Analysis of textual data available on the web. Sentiment Analysis has its challenges, and one of them is Sarcasm. Classification of sarcastic sentences is a difficult task due to representation variations in the textual form sentences. This can affect many Natural Language Processing based applications. Sarcasm is the kind of representation to convey the different sentiment than presented. In our study we have tried to identify different supervised classification techniques mainly used for sarcasm detection and their features. Also we have analyzed results of the classification techniques, on textual data available in various languages on review related sites, social media sites and micro-blogging sites. Furthermore, for each method studied, our paper presents the analysis of data set generation and feature selection process used thereof. We also carried out preliminary experiment to detect sarcastic sentences in “Hindi” language. We trained SVM classifier with 10X validation with simple Bag-Of-Words as features and TF-IDF as frequency measure of the feature. We found that this simple model based on “bag-of-words” feature accurately classified 50% of sarcastic sentences. Thus, primary experiment has revealed the fact that simple Bag-of-Words are not sufficient for sarcasm detection.
Posttraumatic growth in aging individuals who have lost their only child in China

ABSTRACT This article examined the extent of posttraumatic growth (PTG) and factors related to PTG in aging individuals who have lost their only child in China. The sample included 201 bereaved parents from different families residing in Chongqing, China. They were between 49–80 years old (M = 61) and had lost their only child. Personal interviews were conducted in their homes. PTG was assessed with a revised Posttraumatic Growth Inventory (PTGI–R). Descriptive and multiple linear regression analyses were conducted. Overall, the sample showed a positive tendency toward PTG. The older the child was at death, the less PTG the parent experienced. Time since the child’s death was negatively correlated with PTG, and parents whose children died by accident/suicide had lower PTG than those whose children died of illness. Lower education and poor parental health were significantly associated with lower levels of PTG. Community support was significantly and positively associated with PTG. A majority of aging parents who have lost their only child in China experience PTG. Characteristics related to the loss (child’s age at death, time since the death, and cause of death), personal resources (parent’s education and health), and community support are associated with the degree of growth.
Serum leptin levels negatively correlate with trabecular bone mineral density in high-fat diet-induced obesity mice.

OBJECTIVES This study evaluated the influence of diet-induced obesity on bone tissue quantity and quality in the proximal tibiae of growing mice and also examined the relationships between the serum total cholesterol, leptin, and adiponectin levels and trabecular and cortical bone mineral parameters. METHODS Six-week-old male C57BL/6J mice were divided into two groups; one received a control diet, and the other received a high-fat-diet. After treatment for 4, 8, or 12 weeks, the bone quantity and quality were analyzed using peripheral quantitative computed tomography (pQCT), micro-computed tomography and histomorphometry. RESULTS In the early stages, trabecular bone density decreased with an increase in the number of adipocytes and the deterioration of trabeculae. In contrast, although cortical bone formation was slower in obese mice compared with control mice, bone formation on the periosteal surface increased with age. Serum leptin levels were correlated with trabecular, but not cortical bone density, whereas neither the adiponectin nor total cholesterol level was correlated with bone mass in mice with diet-induced obesity. CONCLUSIONS We conclude that bone loss at these two sites is differentially regulated in mice. Furthermore, we demonstrate that serum leptin may be a useful indicator of risk for osteoporosis associated with diet-induced obesity.
Economics of Beekeeping in Ganye Local Government Area of Adamawa State, Nigeria

DOI: 10.15580/GJAS.2018. 7.071318096 The study was carried out in Ganye local government area of Adamawa State on the “Economics of Beekeeping”. A total of 46 beekeepers was randomly selected and interviewed in the study area. Well-structured questionnaire (46) was employed to collect useful and relevant data from the respondents. The data collected were analysis using descriptive statistics, gross margin, profitability ratio analysis and multiple regression analysis. The result of socio-economic characteristics of the respondents shows that 67.39% of the beekeepers were within the highly productive age range of 30 – 49 years with most (91.3%) of the beekeepers being male. The results of gross margin and profitability analysis indicates net farm income of N45,210.00, return on investment per naira is N1.34. This indicates that beekeeping is a lucrative enterprise. The result of multiple regression analysis showed that age , sex , educational level , beekeeping experience , number of hives , labour cost , cost of hives , were all positively related to productivity. The coefficient of transportation cost was negatively related and is not significant. The coefficient of educational level and beekeeping experience were positive and significant at 1% level of probability. The coefficient of number of hives and cost of hives were positive and were significant at 5% and 10% respectively. The identified problems include inadequate capital, lack of good storage facilities, high cost of packaging materials, transportation problem, low yield, technology too expensive, inadequate skilled manpower and theft. Based on the findings it was recommended that government should subsidize inputs for the farmers, assist them with loan and give them proper orientation on the benefit of beekeeping. Submitted: 13/07/2018 Accepted: 25/07/2018 Published: 27/07/2018
Competitive intelligence failures from the perspective of information behaviour

Failures in competitive intelligence are widely reported but are seldom studied through an information behaviour lens or specifically attributed to information activities and factors influencing information behaviour. This dissertation addresses this gap. The research question was: How are competitive intelligence failures attributed to information behaviour? Sub-questions included:  How is lack of understanding of competitive intelligence contributing to competitive intelligence failure?  How are the identification and expression of intelligence needs contributing to competitive intelligence failures?  How are difficulties experienced in data collection contributing to competitive intelligence failures?  How are information sharing and specifically feedback mechanisms contributing to competitive intelligence failures?  How are other information activities (apart from the recognition and expression of information needs, data collection and information sharing) o contributing to competitive intelligence failures? o preventing competitive intelligence failures? Eclectic versions of the competitive intelligence life cycle (mostly based on the Bose (2008) and Botha and Boon (2008) interpretations) and information-seeking/information behaviour model (mostly based on the Wilson (1981) and Leckie, Pettigrew and Sylvain (1996) models) served as conceptual frameworks for data collection and analysis. The study followed a survey method using semi-structured individual interviews with 15 competitive intelligence professionals, educators and trainers. They were recruited through purposive and snowball sampling. A profile questionnaire of limited scope collected descriptive quantitative data on educational level, professional position, formal training in competitive intelligence and description of job titles. Semi-structured individual interviews were conducted through face-to-face, SKYPE, telephonic call and face-time call interviews. Data was collected from 31/08/2016 to 30/01/2017. Thematic analysis was applied to the qualitative data, identifying core themes and sub-themes for each sub-problem. Findings are used to populate the two frameworks: competitive intelligence cycle and information behaviour, before suggesting a framework with elements from both to guide future studies on competitive intelligence failures from an information behaviour perspective. Suggestions for theories to consider in future research, competitive intelligence practices, and further research are included.
Automatic structural scene digitalization

In this paper, we present an automatic system for the analysis and labeling of structural scenes, floor plan drawings in Computer-aided Design (CAD) format. The proposed system applies a fusion strategy to detect and recognize various components of CAD floor plans, such as walls, doors, windows and other ambiguous assets. Technically, a general rule-based filter parsing method is fist adopted to extract effective information from the original floor plan. Then, an image-processing based recovery method is employed to correct information extracted in the first step. Our proposed method is fully automatic and real-time. Such analysis system provides high accuracy and is also evaluated on a public website that, on average, archives more than ten thousands effective uses per day and reaches a relatively high satisfaction rate.
Does IFRS Convergence Really Increase Accounting Qualities? Emerging Market Evidence

Purpose This study aims to examine whether International Financial Reporting Standards (IFRS) convergence process adds value to the accounting quality dimensions, including accruals quality, earnings smoothing, timely loss recognition and earnings persistence. Design/methodology/approach It analyzes the hypothesis of accounting quality changes in post-IFRS convergence by using the univariate and multivariate statistics. Particularly, the authors rely on panel data analyses using industrial companies’ data from 2008 until 2014, comprising 3,861 firm-years observations, in Indonesia. Findings The results indicate that there is no conclusive evidence that all accounting quality dimensions including accruals quality, earnings smoothing, timely loss recognition and earnings persistence increased in post-IFRS convergence. Practical implications The findings of this study may help regulators and standard setters to consider future adoption of IFRS, mostly to figure out the best “formula” to increase the usefulness of accounting information in post-IFRS convergence. Originality/value Rather than doing piecemeal work, the current study focuses on IFRS convergence on a broader aspect of accounting quality dimensions. It also focuses on the convergence process of IFRS as an alternative of full adoption, which has been the focus of many research studies.
Rotational motion of a nanosatellite using onboard electromagnetic coils after collision with a solid high-speed particle

In this study, we model a collision of a nanosatellite with space debris or micrometeoroids, leading to rotational motion of a nanosatellite. We consider the problem of controlled reduction of acquired angular velocity of a nanosatellite. The control process is based on the use of three electromagnets.
The effect of environmental performance and accounting characteristics to earnings informativeness

The objective of this empirical study is to analyze the influence of environmental performance and company’s accounting characteristics to earnings informativeness proxied by earnings response coefficient (ERC) on manufacturing companies listed on Indonesia Stock Exchange and consistently follow the PROPER assessment in 2010–2014. One of the company’s considerations is to create the green environment reflecting its environmental measures, drawing investors to respond to the company’s environmental performance. The data were obtained from Indonesian Capital Market Directory (ICMD), the Indonesia Stock Exchange homepage, the company’s annual reports, the decree of the Minister of Environment. The samples used in this research are 27 go public manufacturing companies listed on Indonesia Stock Exchange that consistently follow the PROPER in 2010–2014. The sampling technique used was the purposive method. This research uses multiple regression analysis. The results show that the environmental performance and profitability have a positive influence to earnings informativeness, while leverage has a negative influence to earnings informativeness. Growth opportunities as a control variable has a positive effect on earnings informativeness. This research has proved that the environmental performance is crucial through observing the investors’ reaction in the capital market.