Miracle-dz/UniFAR-FTUs huggingface dataset:
Use of the Binomial Distribution to Predict Impairment: Application in a Nonclinical Sample

A mathematical model based on the binomial theory was developed to illustrate when abnormal score variations occur by chance in a multitest battery (Ingraham & Aiken, 1996). It has been successfully used as a comparison for obtained test scores in clinical samples, but not in nonclinical samples. In the current study, this model has been applied to demographically corrected scores on the Halstead-Reitan Neuropsychological Test Battery, obtained from a sample of 94 nonclinical college students. Results found that 15% of the sample had impairments suggested by the Halstead Impairment Index, using criteria established by Reitan and Wolfson (1993). In addition, one-half of the sample obtained impaired scores on one or two tests. These results were compared to that predicted by the binomial model and found to be consistent. The model therefore serves as a useful resource for clinicians considering the probability of impaired test performance.
A resolution-controllable harmonical retrieval approach on the Chrestenson discrete space

The conventional harmonical retrieval problem is considered in the Chrestenson (1955) function space. The purpose is to elucidate the relations between the Chrestenson and Fourier transform and also their difference through the harmonical retrieval problem. It can be shown that the spectral resolution and precision can be controlled by the Chrestenson function order p. It is also concluded that if the autocorrelation data is p and a signal is assumed as p-adic stationary, the spectra obtained by the Chrestenson transform is its maximum entropy estimation. >
Parallel K-Means Clustering with Triangle Inequality

Clustering divides data objects into groups to minimize the variation within each group. This technique is widely used in data mining and other areas of computer science. K-means is a partitional clustering algorithm that produces a fixed number of clusters through an iterative process. The relative simplicity and obvious data parallelism of the K-means algorithm make it an excellent candidate for distributed-memory parallel optimization, particularly as datasets grow beyond the size of a single machine. The triangle inequality, when applied to the K-means algorithm, allows unnecessary distance calculations between data objects and cluster centroids to be avoided. Various parallel implementations of the K-means algorithm exist, but no example comparing a standard parallel implementation to one utilizing the triangle inequality could be located. This paper seeks to fill this gap by presenting experimental results demonstrating the performance of both standard and improved parallel K-means implementations compared to a sequential implementation. keywords: K-means, clustering, data mining, parallel, triangle inequality
The isolation of glycerol-fermenting and lipolytic bacteria from the rumen of the sheep.

SUMMARY: Facultatively anaerobic bacteria appear to play little part in glycerol fermentation in the sheep rumen. Amongst the most important members of the glycerol-fermenting flora are strict anaerobes of the group Selenomonas ruminantium var. lactilyticas. Three isolates of a different group of strictly anaerobic curved Gram-negative rods, which hydrolyse linseed oil and tributyrin as well as fermenting glycerol, were obtained in numbers which suggest they are amongst the more important lipolytic bacteria in the rumen. The main product of fermentation of glycerol by the selenomonads and the lipolytic bacteria is propionic acid, but other acids are also formed. The properties of these bacteria and some others isolated during the experiments are described. All the bacteria appear to be normal inhabitants of the rumen of sheep fed a number of different rations. The numbers of these organisms were not appreciably increased by feeding glycerol or triglycerides to the animals.
A New Method for Variance Estimation of White Noise Corrupting a Signal

Presented in this paper is a new method for estimating the variance of white noise corrupting a signal using Donoho and Johnstone (D-J) threshold. For piecewise smooth signals with limited number of incontinuities, the new method is insensitive to outliers, i.e., the large value coefficients associated to signal incontinuities, and is of higher efficiency than the median absolute deviation (MAD)-based variance estimator. Evaluation of the new method is implemented using a simulated piecewise smooth signal and a real differential pressure signal. Comparisons with the MAD-based variance estimator are also given
Fingerprint enhancement over the past few years

This paper furnishes a review of the research trends and the methodologies adopted and adapted for enhancing fingerprints in the recent past. Our area of focus is primarily latent fingerprints. Previously, the studies on fingerprint enhancement segregate the techniques mostly in spatial and frequency domains. But, in our paper we have broadly divided the enhancement technics into Gabor based and non-Gabor based (variations of conventional Gabor and others).
Internet Message Board Activity and Market Efficiency: A Case Study of the Internet Service Sector Using Ragingbull.Com

This paper examines the relationships between internet message-board activity and abnormal stock returns and between internet message-board activity and abnormal trading volume.This study focuses on RagingBull.com and internet service sector stocks. I choose RagingBull.com because its format enables me to measure investor opinion objectively. I find that on days with abnormally high message activity changes in investor opinion correlate with with abnormal industry-adjusted returns. Additionally, days with abnormally high message activity coincide with abnormally high trading volume both that day and the following day. However, I find that, in general, message-board activity does not predict industry-adjusted returns or abnormal trading volume.
Two Wrongs Do Not Make a Right

This paper analyzes proposals to remedy tax-induced distortions in health care by using new tax incentives and retaining all of the existing distortionary tax incentives. In the process of remedying some distortions, this approach magnifies others—most notably increasing the total tax preference for health care. The paper considers two examples—the Bush administration's FY 2007 budget proposal and a plan by Cogan, Hubbard and Kessler (2005)—and shows that both could result in higher health spending and reduced welfare. Finally, the paper discusses the circumstances in which tax incentives could be warranted to remedy market failures in health insurance.
THE PATHOGENESIS AND PATHWAY INTO THE CENTRAL NERVOUS SYSTEM AFTER INTRAOCULAR INFECTION OF HERPES SIMPLEX VIRUS TYPE I IN RABBITS

Herpes simplex virus (HSV) type I was injected into the right eye of 18‐day‐old New Zealand albino rabbits and the animals were killed on the fourth and eighth days after inoculation. Longitudinal section of the optic nerves and chiasma showed that both myelinated axons and neuroglial cells crossed at the chiasma. Semi‐serial (1 μm) and ultrathin sections showed the presence of HSV in both astrocytes and oligodendrocytes, although no particles were seen in the myelinated axons; the infected cells were confined to the medial side of the right optic nerve. HSV travels centropetally along the optic pathway and slowly spreads laterally by cell‐to‐cell infection. The virus does not appear to kill the astrocytes and oligodendrocytes, and also does not directly damage the myelin sheath.
OPTIMIZACIÓN DE RUTA CORTA USANDO ALGORITMO GENÉTICO GENERACIONAL

El presente artículo de investigación tiene como objetivo utilizar algoritmo genético generacional, propio de la inteligencia artificial, donde se aprovecha el proceso evolutivo para optimizar el recorrido de los n puntos o nodos, a un coste de computador menor. Una de las ventajas de este método evolutivo es que no compiten todos contra todos, sinoque se crea y procesa una porción de la población total, con el objetivo de encontrar la posible mejor ruta, o también llamada búsqueda local. Se ha considerado para el método de la ruleta, cruce por intercambio de 2 puntos, mutación por intercambio y método de parada de acuerdo a la cantidad de generaciones. En un computador de regular característica selogró implementar el algoritmo genético generacional en lenguaje Matlab 8.3, tomando como ejemplo las distancias de cada ciudad. Se obtuvieron como resultados para n puntos o nodos, en cada evaluación, las posibles mejores rutas basándose en el modelo evolutivo. Las pruebas realizadas desde 100 hasta 1000 ciudades resultaron en tiempos de 3,2006 s y 27,924 s, respectivamente. De acuerdo al conjunto de pruebas, demuestra un incremento de manera polinómica de nivel 2; por lo que esta investigación se centra en el incremento de los dos métodos de parada a una secuencia lineal.
Influence of Variation in the Follicle-Stimulating Hormone Receptor Gene (FSHR) and Age at Menopause on the Development of Alzheimer’s Disease in Women

Background: The higher prevalence of sporadic Alzheimer’s disease (AD) in women may be explained by their longer life expectancy, but also by biological gender-specific factors such as a woman’s past fertility. Methods: We investigated the relationship between fertility and susceptibility to AD in women by studying two polymorphisms at codons 307 and 680 of the follicle-stimulating hormone receptor gene (FSHR) involved in determining human fertility. The role of age at menopause (AM) as a gender-specific AD susceptibility determinant was also examined. The study population comprised 291 AD patients (70.1% women) and 134 controls (63.4% women). Results: Logistic regression analysis showed that only among the women the FSHR AS/AS genotype was associated with a significantly lower risk of AD (OR = 0.36, 95% CI: 0.15–0.85), suggesting a gender-specific protective role of the FSHR genotype against AD susceptibility. A lower age at natural menopause was observed in the AD patients (49.7 ± 2.53) than in the controls (50.7 ± 2.53, p = 0.02) and on linear regression analysis an association emerged between an earlier AM and an earlier AD onset (p = 0.004). Conclusions: Genetic and non-genetic gender-specific factors may contribute to the AD pathogenesis in women, although further investigations are required to clarify their actual role.
Denitrifying Bacteria from the Genus Rhodanobacter Dominate Bacterial Communities in the Highly Contaminated Subsurface of a Nuclear Legacy Waste Site

ABSTRACT The effect of long-term mixed-waste contamination, particularly uranium and nitrate, on the microbial community in the terrestrial subsurface was investigated at the field scale at the Oak Ridge Integrated Field Research Challenge (ORIFRC) site in Oak Ridge, TN. The abundance, community composition, and distribution of groundwater microorganisms were examined across the site during two seasonal sampling events. At representative locations, subsurface sediment was also examined from two boreholes, one sampled from the most heavily contaminated area of the site and another from an area with low contamination. A suite of DNA- and RNA-based molecular tools were employed for community characterization, including quantitative PCR of rRNA and nitrite reductase genes, community composition fingerprinting analysis, and high-throughput pyrotag sequencing of rRNA genes. The results demonstrate that pH is a major driver of the subsurface microbial community structure and that denitrifying bacteria from the genus Rhodanobacter (class Gammaproteobacteria) dominate at low pH. The relative abundance of bacteria from this genus was positively correlated with lower-pH conditions, and these bacteria were abundant and active in the most highly contaminated areas. Other factors, such as the concentration of nitrogen species, oxygen level, and sampling season, did not appear to strongly influence the distribution of Rhodanobacter bacteria. The results indicate that these organisms are acid-tolerant denitrifiers, well suited to the acidic, nitrate-rich subsurface conditions, and pH is confirmed as a dominant driver of bacterial community structure in this contaminated subsurface environment.
Phase I and Pharmacokinetic Study of the Dolastatin-15 Analogue Tasidotin (ILX651) Administered Intravenously on Days 1, 3, and 5 Every 3 Weeks in Patients with Advanced Solid Tumors

Purpose: To determine the maximum tolerated dose (MTD), dose-limiting toxicity (DLT), and pharmacokinetics of tasidotin (ILX651), a dolastatin-15 analogue, when administered on days 1, 3, and 5 every 3 weeks in patients with advanced solid tumors. Patients and Methods: Thirty-two patients were treated with 92 courses of tasidotin through seven dose levels determined by a modified Fibonacci scheme ranging from 3.9 to 45.7 mg/m2. Pharmacokinetic samples were collected during the first course. Results: Neutropenia was the principal DLT at the 45.7 mg/m2/d dose level. In addition, one patient also experienced grade 3 neutropenia complicated with grade 3 esophageal candidiasis and grade 3 dehydration. Only 1 of 11 patients treated at the MTD, 34.4 mg/m2, experienced dose-limiting neutropenia. Other common, drug-related toxicities included mild to moderate fatigue, anemia, nausea, anorexia, emesis, alopecia, and diarrhea. The best observed antitumor response consisted of stable disease and was noted in 10 patients (31%); the median duration on study for those patients with stable disease was 99.5 days compared with 37.5 days for those patients with progressive disease. Tasidotin plasma concentrations declined biphasically with an effective half-life of ≤55 minutes, and ∼11% was excreted unchanged in the urine. Conclusion: The recommended dose for phase II studies and the MTD when tasidotin is administered on days 1, 3, and 5 every 3 weeks is 34.4 mg/m2. The favorable toxicity profile of tasidotin compared with other antitubulin agents, including other dolastatin analogues, and its novel mechanism of action support further disease-directed evaluation of this agent.
A common sleep disorder in pregnancy: Restless legs syndrome and its predictors

Restless legs syndrome (RLS) is common in the third trimester of pregnancy. In this case–control study, 22.5% of 211 women had RLS. The RLS cases had a history of growing pains (GP) more frequently than controls (P = 0.042). A family history of GP (P = 0.025) and RLS (P = 0.018) was more frequent among cases than controls. RLS in pregnancy is predicted by family history of RLS and GP, and by childhood history of GP.
A cell‐specific enhancer far upstream of the mouse tyrosinase gene confers high level and copy number‐related expression in transgenic mice.

The tyrosinase gene encodes the key enzyme of melanin production and is tightly regulated during development. A yeast artificial chromosome covering the mouse tyrosinase gene has been shown to rescue completely the albino phenotype of recipient mouse strains, conferring copy number‐dependent, position‐independent expression. To investigate the presence of cis‐acting regulatory elements responsible for the appropriate expression of the tyrosinase gene, DNase I hypersensitive site mapping was performed. A melanoma cell‐specific DNase I hypersensitive site was identified at ‐12 kb upstream of the tyrosinase gene. Functional analysis of the corresponding cis‐acting element in transgenic mice and transient transfection assays revealed properties of a strong cell‐specific enhancer. RNA expression levels of the transgene correlate with copy number, which is reflected in coat colour and eye pigmentation of transgenic mice. Full enhancer activity in transient transfections is obtained with a minimal sequence of 200 bp. Protein binding analysis reveals the presence of a melanoma cell‐specific complex which might contribute to the faithful expression of the tyrosinase gene.
Resolution improvement for UWB wallscanning radar applications

An important quality criterion of radar systems is the maximum obtainable resolution. This limit is reached when echoes coming from adjacent objects overlap and it is no longer possible to distinguish between them. This paper presents an algorithm formulating the echo separation as an optimization algorithm. The basic idea is to model each received signal as a linear superposition of reference signals. The parameters of the model are obtained by using evolutionary optimization strategies. An example of imaging two pipes placed in a concrete wall verifies the proposed principle experimentally.
Shape correspondence between a spatial curve and a manipulator with hyper degrees of freedom

In this paper, we give a definition of a shape correspondence between a manipulator with hyper degrees of freedom and a spatial curve. The shape correspondence is defined by using the solution of a nonlinear optimization problem, termed the shape inverse problem. We also provide results on the existence and a well-posed region of the solution.
Critical Theory and Interaction Design

Classic texts by thinkers from Althusser to Žižek alongside essays by leaders in interaction design and HCI show the relevance of critical theory to interaction design. Why should interaction designers read critical theory? Critical theory is proving unexpectedly relevant to media and technology studies. The editors of this volume argue that reading critical theory—understood in the broadest sense, including but not limited to the Frankfurt School—can help designers do what they want to do; can teach wisdom itself; can provoke; and can introduce new ways of seeing. They illustrate their argument by presenting classic texts by thinkers in critical theory from Althusser to Žižek alongside essays in which leaders in interaction design and HCI describe the influence of the text on their work. For example, one contributor considers the relevance Umberto Eco's “Openness, Information, Communication” to digital content; another reads Walter Benjamin's “The Author as Producer” in terms of interface designers; and another reflects on the implications of Judith Butler's Gender Trouble for interaction design. The editors offer a substantive introduction that traces the various strands of critical theory. Taken together, the essays show how critical theory and interaction design can inform each other, and how interaction design, drawing on critical theory, might contribute to our deepest needs for connection, competency, self-esteem, and wellbeing. Contributors Jeffrey Bardzell, Shaowen Bardzell, Olav W. Bertelsen, Alan F. Blackwell, Mark Blythe, Kirsten Boehner, John Bowers, Gilbert Cockton, Carl DiSalvo, Paul Dourish, Melanie Feinberg, Beki Grinter, Hronn Brynjarsdottir Holmer, Jofish Kaye, Ann Light, John McCarthy, Soren Bro Pold, Phoebe Sengers, Erik Stolterman, Kaiton Williams. , Peter Wright Classic texts Louis Althusser, Aristotle, Roland Barthes, Seyla Benhabib, Walter Benjamin, Judith Butler, Arthur Danto, Terry Eagleton, Umberto Eco, Michel Foucault, Wolfgang Iser, Alan Kaprow, Soren Kierkegaard, Bruno Latour, Herbert Marcuse, Edward Said, James C. Scott, Slavoj Žižek
Disiplinler Arası Yaklaşımla Değer Öğretiminde Yaratıcı Drama Yönteminin Kullanılması

Bu arastirmada disiplinler arasi yaklasimla deger ogretiminde yaratici drama yonteminin kullanilmasinin, ogrencilerin “Duygu ve dusuncelere saygi, hosgoru” ve “Bilimsellik” degerlerine iliskin tutumlarina etkisi tespit edilmistir. Arastirma, nitel ve nicel arastirma yontemlerinin birlikte uygulandigi karma yontem (Mixed Method) desenlerinden yakinsayan paralel desen kullanilarak modellenmistir. Arastirmanin calisma grubunu, 2013-2014 egitim ogretim yili guz doneminde Ankara iline bagli bir merkez ilce olan Akyurt ilcesinde bulunan bir devlet okulunda ogrenim gormekte olan ilkokul 4. sinif ogrencileri olusturmaktadir. Veri toplama surecinde ogrencilerin “Duygu ve dusuncelere saygi, hosgoru” degerlerine yonelik tutumlarini belirlemek amaciyla “Duygu ve Dusuncelere Saygi, Hosgoru Tutum Olcegi”, “Bilimsellik” degerine yonelik tutumlarini belirlemek amaciyla “Bilimsellik Tutum Olcegi”, ogrencilerin surece iliskin goruslerini belirlemek amaciyla “Gorus Belirleme Formu” arastirmacilar tarafindan gelistirilmis ve kullanilmistir. Arastirmanin nicel veri analizlerinde bagimli gruplar t-testi, bagimsiz gruplar t-testi, Mann Whitney U testi ve Wilcoxon Isaretli Siralar testi kullanilmistir. Nitel verilerin analizinde ise icerik analizi yaklasimindan yararlanilmistir. Arastirma sonucunda disiplinler arasi yaklasimla deger ogretiminde yaratici drama yonteminin kullanildigi deney grubu ogrencilerinin, ele alinan degerlere yonelik tutum puanlarinin yukseldigi tespit edilmistir. Disiplinler arasi yaklasimla deger ogretiminde yaratici drama yonteminin kullanilmasinin degerlerin kazandirilmasinda oldukca etkili oldugu, ogrenme surecini somutlastirdigi, ogrenciler icin eglenceli ve mutlu olduklari bir ogrenme ortami olusturdugu gozlemlenmistir.
How can the current strategies for Helicobacter pylori eradication therapy be improved?

BACKGROUND The use of Helicobacter pylori eradication therapy is advocated in an increasing variety of situations. It is therefore important to optimise current strategies to eradicate H pylori infection. OBJECTIVES To define the optimum dosage, drugs and duration of proton pump inhibitor (PPI) triple therapy. METHODS A review of the literature was performed to identify randomized controlled trials and systematic reviews addressing these issues. RESULTS In PPI, amoxicillin and clarithromycin (PAC) based regimens, twice daily PPI gave optimal eradication rates (relative risk reduction [RRR] compared with once daily = 7%; 95% CI 2% to 12%), but in PPI, clarithromycin and metronidazole (PCM) based regimens there was no difference (RRR = 2%; 95% CI -7% to 10%). Omeprazole and lansoprazole-containing triple therapies achieved similar eradication rates, but rabeprazole appeared superior to omeprazole (RRR = 8%; 95% CI 2% to 14%). The optimum clarithromycin dose in a PAC regimen was 500 mg twice daily (RRR = 11%; 95% CI = 3% to 18%), but 250mg twice daily in a PCM regimen (RRR = 2%; 95% CI -4% to 7%). Eradication rates were lower with a seven day regimen compared with fourteen (RRR = 12%; 95% CI 7% to 17%). Overall there was no difference between a PAC and a PCM regimen (RRR = 0%; 95% CI -3% to 3%). CONCLUSIONS PAC and PCM regimens are equally effective if used optimally, though PCM is cheaper. The eradication regimen and its duration should be tailored according to the clinical situation.
High-Sensitivity Ozone Sensing Using 280 nm Deep Ultraviolet Light-Emitting Diode for Detection of Natural Hazard Ozone

Recently ozone is one of natural hazards which comes from cars, industry using ozone for sterilization of organic and inorganic materials and for water purification. So, ozone sensing becomes very important, and convenient and accurate ozone sensor is required. A new high sensitivity ozone sensing system using an deep ultra-violet light emitting diode (DUV-LED) operated at the wavelength of 280 nm has been successfully constructed. The fabrication of diode operated at 280 nm is much easier than that of DUV-LED operated at Hg lamp wavelength of 254 nm. The system is compact and possible to sense the ozone concentration less than 0.1 ppm with an accuracy of 0.5% easily with low power DUV-LED of around 200 micro Watts operated at 280 nm without any data processing circuit.