Miracle-dz/UniFAR-FTUs huggingface dataset:
CLEF 2018 Technologically Assisted Reviews in Empirical Medicine Overview

Conducting a systematic review is a widely used method to obtain an overview over the current scientiﬁc consensus on a topic of interest, by bringing together multiple studies in a reliable, transparent way. The large and growing number of published studies, and their increasing rate of publication, makes the task of identifying all relevant studies in an unbiased way both complex and time consuming to the extent that jeopardizes the validity of their ﬁndings and the ability to inform policy and practice in a timely manner. The CLEF 2018 e-Health Technology Assisted Reviews in Empirical Medicine task aims at evaluating search algorithms that seek to identify all studies relevant for conducting a systematic review in empirical medicine. The task had a focus on Diagnostic Test Accuracy (DTA) reviews, and consisted of two subtasks: 1) given a number of relevance criteria as described in a systematic review protocol, search a large medical database of article abstracts (PubMed) to ﬁnd the studies to be included in the review, and 2) given the article abstracts retrieved by a carefully designed Boolean Query, prioritize them to reduce the eﬀort required by experts to screen the abstracts for inclusion in the review. Seven teams participated in the task, with a total of 12 runs submitted for subtask 1 and 19 runs for subtask 2. This paper reports both the methodology used to construct the benchmark collection, and the results of the evaluation.
A prospective longitudinal study of social, psychological and obstetric factors in pregnancy: response rates and demographic characteristics of the 8556 respondents

This paper introduces the Mater Misericordiae Mothers' Hospital‐University of Queensland Study of Pregnancy, a prospective study of 8556 pregnant women interviewed at their first clinic visit, and subsequently interviewed some days after the birth of the baby and again 6 months later. Additional data were derived from the medical record of the pregnancy and delivery. The study was designed to assess the impact of social, psychological and obstetric factors on pregnancy outcome. We present here details of the study design, sampling, response rates and demographic characteristics of the sample.
Investigations of oocyte in vitro maturation within a mouse model

This study attempted to develop a ‘less meiotically competent’ murine model for oocyte in vitro maturation (IVM), which could more readily be extrapolated to human clinical assisted reproduction. Oocyte meiotic competence was drastically reduced upon shortening the standard duration of in vivo gonadotrophin stimulation from 48 h to 24 h, and by selecting only naked or partially naked germinal vesicle oocytes, instead of fully cumulus enclosed oocyte complexes. With such a less meiotically competent model, only porcine granulosa coculture significantly enhanced the oocyte maturation rate in vitro, whereas no significant enhancement was observed with macaque and murine granulosa coculture. Increased serum concentrations and the supplementation of gonadotrophins, follicular fluid and extracellular matrix gel within the culture medium did not enhance IVM under either cell-free or coculture conditions. Culture medium conditioned by porcine granulosa also enhanced the maturation rate, and this beneficial effect was not diminished upon freeze–thawing. Enhanced IVM in the presence of porcine granulosa coculture did not, however, translate into improved developmental competence, as assessed by in vitro fertilization and embryo culture to the blastocyst stage.
Self-Inhibition of Synthesis and Antigen Presentation by Epstein-Barr Virus-Encoded EBNA1

The glycine-alanine repeat domain (GAr) of Epstein-Barr virus–encoded nuclear antigen 1 (EBNA1) prevents major histocompatibility complex (MHC) class I–restricted presentation of EBNA1 epitopes to cytotoxic T cells. This effect has previously been attributed to the ability of GAr to inhibit its own proteasomal degradation. Here we show, both in vitro and in vivo, that GAr also inhibits messenger RNA translation of EBNA1 in cis and that this effect can be distinguished from its effect on proteasomal degradation. Hence, inhibition of messenger RNA translation, but not protein degradation, is essential to prevent antigen presentation on MHC class I molecules. Thus, by minimizing translation of the EBNA1 transcript, cells expressing EBNA1 avoid cytotoxic T cell recognition. At the same time, blocking degradation maintains the EBNA1 expression level.
The real time system

The Real Time System described herein was designed and implemented for the purpose of serving Univa c Management at all levels with an inquiry/response, updat e and data collection tool fitting the precise requirements o f the Company . The system was not intended to be offere d as a generalized software package . The system runs on the 1108 Computer installed a t Univac Headquarters in Blue Bell, Pennsylvania . Exec VII I Level 27 is currently employed . Further details relative t o the hardware configuration are provided by the attache d chart . There were several elements considered in the initia l design of the system . These elements may be divided int o three categories : User considerations, programming considerations, and operational considerations .
Considerations in Speech Recognition Testing of Bilingual and Spanish-Speaking Patients Part I : Older Children and Adults

The rapid growth of the Spanish-speaking population of the United States presents challenges for all healthcare providers to develop linguisticallyand culturallyappropriate best practices. A significant need for all audiologists is language-appropriate stimuli for speech recognition testing. Unfortunately, few well-validated tests exist for this purpose. We review the timeline of development of Spanish-language speech recognition test materials and address issues facing the audiologist in evaluating accurately the hearing abilities of both older children and adults who use Spanish as their primary or only language of communication.
Specific detection of methicillin-resistant Staphylococcus species by multiplex PCR

Vannuffel and coworkers (1) offer an interesting approach to the problem of rapid and specific detection of methicillinresistant Staphylococcus aureus in clinical specimens. This approach is based on the premise that methicillin-resistant S. aureus strains harbor both mecA and femA genes, while methicillin-resistant coagulase-negative staphylococci (CNS) carry the mecA gene only. The authors detect both genes directly in clinical samples (e.g., blood samples) by multiplex PCR and claim that this simultaneous detection identifies both the species and its phenotypic resistance. We see a major problem with this approach: the species determination fails as soon as the clinical sample does not contain a pure culture of either S. aureus or CNS. Indeed, the femA gene is present in all S. aureus strains, irrespective of the presence of the mecA gene. This means that a mixed population of methicillin-susceptible S. aureus (e.g., in blood) and methicillin-resistant CNS (e.g., from skin contamination) will also generate two DNA fragments in the multiplex PCR and result in the erroneous identification of methicillin-resistant S. aureus. We agree with Vannuffel et al. that a rapid and reliable test for identification of methicillin-resistant S. aureus might help the clinicians in reducing the use of glycopeptide antibiotics in the hospital. Unfortunately, simultaneous detection of femA and mecA genes directly in clinical samples is not the answer.
A Survey of Distance and Similarity Measures Used Within Network Intrusion Anomaly Detection

Anomaly detection (AD) use within the network intrusion detection field of research, or network intrusion AD (NIAD), is dependent on the proper use of similarity and distance measures, but the measures used are often not documented in published research. As a result, while the body of NIAD research has grown extensively, knowledge of the utility of similarity and distance measures within the field has not grown correspondingly. NIAD research covers a myriad of domains and employs a diverse array of techniques from simple k-means clustering through advanced multiagent distributed AD systems. This review presents an overview of the use of similarity and distance measures within NIAD research. The analysis provides a theoretical background in distance measures and a discussion of various types of distance measures and their uses. Exemplary uses of distance measures in published research are presented, as is the overall state of the distance measure rigor in the field. Finally, areas that require further focus on improving the distance measure rigor in the NIAD field are presented.
Soft sensor modeling of mill level based on Deep Belief Network

Accurate measurement of the mill level is a key factor to improve the ball mill's productive efficiency, safety and economy. Aiming at solving the critical problem of the mill level soft sensor, feature extraction of the processing parameters, a novel method based on Deep Belief Network (DBN) is proposed. DBN is one of the deep learning methods, which focuses on learning deep hierarchical models of data. In this paper, basic features, namely power spectrum density are obtained from the vibration signal of ball mill by Welch's method firstly. Then DBN is built on the basic features to learn high level deep features. Finally a supervised learning algorithm named back propagation neural network is used to model the relationships between extracted features and mill level. Experimental results indicate that the DBN based method outperforms traditional feature extraction methods.
Driven‐equilibrium radiofrequency pulses in NMR imaging

Driven‐equilibrium pulse techniques are applied to NMR imaging to extend the possibilities of manipulating image contrasts in pulse sequences with a high repetition rate. In many cases the data acquisition time can be much shorter than in more conventional pulse techniques. Both calculations and experiments reveal that the intensity of tissue with slowly relaxing nuclear magnetizations can significantly be enhanced, thus facilitating the detection of a number of pathologies.
Low-Income Fathers’ Influence on Children

This article examines what we know about how low-income fathers matter for children. The authors first provide a theoretical background about how parents generally (and fathers more specifically) are expected to influence children’s development and well-being. The authors note the importance of considering differences across children’s age, gender, and race/ethnicity; and they identify key methodological challenges in this area. Then, they summarize the literature on residential fathers and child well-being, finding that greater involvement has been linked to better outcomes for children; however, much of this research has been conducted on more socioeconomically advantaged samples. For fathers who live away from their children, child support payments appear to improve children’s outcomes, but the benefits of father-child interaction are much less clear and likely depend on the quality of the interaction and the characteristics of fathers. Overall, the authors conclude that low-income fathers can have a positive influence on children’s well-being, but the evidence about the population overall is rather weak.
Beneficial Immunomodulation by Streptococcus mutans Anti-P1 Monoclonal Antibodies Is Fc Independent and Correlates with Increased Exposure of a Relevant Target Epitope1

We showed previously that deliberate immunization of BALB/c mice with immune complexes (IC) of the cariogenic bacterium Streptococcus mutans and mAbs against its surface adhesin P1 results in changes in the specificity and isotype of elicited anti-P1 Abs. Depending on the mAb, changes were beneficial, neutral, or detrimental, as measured by the ability of the serum from immunized mice to inhibit bacterial adherence to human salivary agglutinin by a BIAcore surface plasmon resonance assay. The current study further defined changes in the host response that result from immunization with IC containing beneficial mAbs, and evaluated mechanisms by which beneficial immunomodulation could occur in this system. Immunomodulatory effects varied depending upon genetic background, with differing results in C57BL/6 and BALB/c mice. Desirable effects following IC immunization were observed in the absence of activating FcRs in BALB/c Fcer1g transgenic mice. mAb F(ab′)2 mediated desirable changes similar to those observed using intact IgG. Sera from IC-immunized BALB/c mice that were better able to inhibit bacterial adherence demonstrated an increase in Abs able to compete with an adherence-inhibiting anti-P1 mAb, and binding of a beneficial immumomodulatory mAb to S. mutans increased exposure of that epitope. Consistent with a mechanism involving a mAb-mediated structural alteration of P1 on the cell surface, immunization with truncated P1 derivatives lacking segments that contribute to recognition by beneficial immunomodulatory mAbs resulted in an improvement in the ability of elicited serum Abs to inhibit bacterial adherence compared with immunization with the full-length protein.
Personality Traits, Religiosity and Sensation Seeking Behavior among Homosexual Males

The present study aimed to investigate the personality traits (extroversion, agreeableness, conscientiousness, openness & neuroticism), religiosity and sensation seeking behavior among homosexual males of Lahore. Through snowball sampling 100 male homosexuals, with an age range between 19-59 years (M.A=27.01; S.D= 7.23) were included in the study. Majority of participants were middle born (39%), last born (34%), first born (12%) and only child (15%). Moreover, 3% had done Matric, 20% had done intermediate, 43% had completed their bachelors, 21% had done masters whereas, 13% had other education. Participants were administered The Sensation Seeking (SSS), Big Five Inventory (BFI), Salience in Religious Commitment Scale (SRCS) and Demographic Questionnaire. Ex-post Facto research design was used. Data was analyzed using Pearson’s Product Moment Coefficient of Correlation. Results showed a significant negative relationship between sensation seeking behavior and agreeableness and neuroticism personality traits of homosexual males. Results showed that homosexual men are warm, friendly, helpful and they find it important to get along with people, further they are also willing to put aside their interests for other people. Moreover, non-significant relationship was FAROOQ, KHAN & JIBEEN 18 found between sensation seeking behavior and extroversion, conscientiousness, openness personality traits and religiosity among homosexual males.
CS 512 Project GitHub: Predicting co-committers

—Link Prediction is an example class of tasks under link mining where techniques are developed to ”explicitly consider these links when building predictive or descriptive models of the linked data”. Other tasks include object ranking, group detection, collective classiﬁcation and subgraph discovery. In this project, we present three algorithms for predicting links for GitHub network.
Rôle de la structure du paysage dans la distribution spatiale et la régulation des colonies de reproduction du Héron cendré (Ardea cinerea) et modélisation de son expansion future

La comprehension du choix de l'habitat est d'une importance cruciale parce qu'il affecte la fitness. Chaque espece choisit son habitat selon les variables ecogeographique qui definissent sa niche ecologique. Pour les oiseaux coloniaux comme le heron cendre, ce choix s'effectue a multiple echelle. Il change d'un niveau paysager a un niveau local : le paysage est associe aux caracteristiques des zones d'alimentation ; l'echelle intermediaire correspond a l'emplacement de la colonie et l'echelle locale a celui du nid. La plupart des etudes sur les herons coloniaux se sont interessees uniquement aux echelles intermediaires et locales, et ont demontre que l'emplacement de la colonie doit etre proche des secteurs d'alimentation. Le site des colonies est a ces emplacements d'exploitation du milieu. Le but de cette etude est d'examiner le role de la structure de paysage dans la distribution des colonies du heron cendre de l'echelle locale a la paysagere.
Preclinical evaluation of riluzole: assessments of ethanol self-administration and ethanol withdrawal symptoms.

BACKGROUND Many of the neurobehavioral effects of ethanol are mediated by inhibition of excitatory N-methyl-D-aspartate (NMDA) and enhancement of inhibitory gamma-amino-butyric-acid (GABA) receptor systems. There is growing interest in drugs that alter these systems as potential medications for problems associated with alcoholism. The drug riluzole, approved for treatment of amyotrophic lateral sclerosis (ALS), inhibits NMDA and enhances GABA(A) receptor system activity. This study was designed to determine the preclinical efficacy of riluzole to modulate ethanol self-administration and withdrawal. METHODS Male C57BL/6J mice were trained to lever press on a concurrent fixed-ratio 1 schedule of ethanol (10% v/v) versus water reinforcement during daily 16-hour sessions. Riluzole (1 to 40 mg/kg, IP) was evaluated on ethanol self-administration after acute and chronic (2 week) treatment. To determine if riluzole influences ethanol withdrawal-associated seizures, mice were fed an ethanol-containing or control liquid diet for 18 days. The effects of a single injection of riluzole (30 mg/kg) were examined on handling-induced convulsions after ethanol withdrawal. RESULTS Acute riluzole (30 and 40 mg/kg) reduced ethanol self-administration during the first 4 hours of the session, which corresponds to the known pharmacokinetics of this drug. Ethanol self-administration was also reduced by riluzole after chronic treatment. Riluzole (30 mg/kg) significantly decreased the severity of ethanol-induced convulsions 2 hours after ethanol withdrawal. CONCLUSIONS These results demonstrate that riluzole decreases ethanol self-administration and may reduce ethanol withdrawal severity in mice. Thus, riluzole may have utility in the treatment of problems associated with alcoholism.
Mutations in the draT and draG genes of Rhodospirillum rubrum result in loss of regulation of nitrogenase by reversible ADP-ribosylation

Reversible ADP-ribosylation of dinitrogenase reductase forms the basis of posttranslational regulation of nitrogenase activity in Rhodospirillum rubrum. This report describes the physiological effects of mutations in the genes encoding the enzymes that add and remove the ADP-ribosyl moiety. Mutants lacking a functional draT gene had no dinitrogenase reductase ADP-ribosyltransferase (DRAT, the draT gene product) activity in vitro and were incapable of modifying dinitrogenase reductase with ADP-ribose in vivo. Mutants lacking a functional draG gene had no dinitrogenase reductase-activating glycohydrolase (DRAG, the draG gene product) activity in vitro and were unable to remove ADP-ribose from the modified dinitrogenase reductase in vivo. Strains containing polar mutations in draT had no detectable DRAG activity in vitro, suggesting likely cotranscription of draT and draG. In strains containing draT and lacking a functional draG, dinitrogenase reductase accumulated in the active form under derepressing conditions but was rapidly ADP-ribosylated in response to conditions that cause inactivation. Detection of DRAT in these cells in vitro demonstrated that DRAT is itself subject to posttranslational regulation in vivo. Mutants affected in an open reading frame immediately downstream of draTG showed regulation of dinitrogenase reductase by ADP-ribosylation, although differences in the rates of ADP-ribosylation were apparent.
Development and evaluation of a geographic information retrieval system using fine grained toponyms

Geographic information retrieval (GIR) is concerned with returning information in response to an information need, typically expressed in terms of a thematic and spa- tial component linked by a spatial relationship. However, evaluation initiatives have of- ten failed to show significant differences between simple text baselines and more complex spatially enabled GIR approaches. We explore the effectiveness of three systems (a text baseline, spatial query expansion, and a full GIR system utilizing both text and spatial in- dexes) at retrieving documents from a corpus describing mountaineering expeditions, cen- tred around fine grained toponyms. To allow evaluation, we use user generated content (UGC) in the form of metadata associated with individual articles to build a test collec- tion of queries and judgments. The test collection allowed us to demonstrate that a GIR- based method significantly outperformed a text baseline for all but very specific queries associated with very small query radii. We argue that such approaches to test collection development have much to offer in the evaluation of GIR.
Utilising Modified UTAUT to Understand Students' Online Shopping Behaviour: A Case of E-Retail Co-Operative Website in Malaysia

This study determines the impact of UTAUT on online shopping behavior among polytechnic students. It also studies the significance of self-efficacy and anxiety on the students' behavioral intention of using e-retail website. It provides an empirical test of three forms of self-efficacy and anxiety towards behavioral intention to shop online. The research subjects were 91,830 polytechnic students from 33 polytechnics in Malaysia. The sampling procedure employed is a multi-stage cluster probability sampling. The questionnaires were distributed to 500 students at five polytechnics. Seven hypotheses were tested during data analysis. Performance expectancy, effort expectancy, social influence, self-efficacy, internet self-efficacy, computer self-efficacy and online shopping self-efficacy were found to have strong significant relationship with behavioral intention. While facilitating condition shows a significant relationship towards user acceptance, internet anxiety and online shopping anxiety have a weak significant relationship towards behavioral intention.
Personal Financial Planning

Generally speaking, we take good care of the first of these-providing for ourselves and our families now, and most of our income goes for present living expenses. There are so many things that we want now, that we sometimes overlook entirely the necessity for providing for the second and third, that is providing for the possibility of not living out our three score years and ten, or if we do, providing for the years after our retirement.
An empirical investigation of campus demographics and reported rapes

ABSTRACT Objective: Rape on college campuses continues to be a pervasive public health issue with approximately 11% of women experiencing rape while in college. As such, it is important to examine factors unique to college campuses that influence the occurrences of rape. Methods: Using data from 1,423 four-year universities (public and private with at least 1,000 students) from the Office of Education and the Clery Act (2014), we examined institutional risk factors, such as tuition, liquor violations, Greek-life, athletic programs, institution type (public vs. private), and geographical location. Results: Public institutions with higher tuition, more liquor violations, and greater numbers of fraternity men and athletes were more likely to report rape on their campuses. Conclusions: Findings suggest that there are university-level characteristics which may increase certain campuses propensity toward violence against women.