Miracle-dz/UniFAR-FTUs huggingface dataset:
New developments in the post-Jungian field

In university settings, it is my habit to begin lectures on analytical psychology, especially to those not taking degrees in Jungian psychology, by asking those present to do a simple association exercise to the word “Jung. ” I ask them to record the first three things that come to mind. From the (by now) 900þ responses, I have found that the most frequently cited theme, words, concepts, or images have (in order) to do with (a) Freud, (b) psychoanalysis, and (c) the Freud–Jung split. The next most frequently cited association concerns (d) Jung’s anti-Semitism and alleged Nazi sympathies. Other matters raised include (e) archetypes, (f) mysticism/philosophy/religion, and (g) animus and anima. Obviously, this is not properly empirical research. But if we “associate to” the associations, we can see that there is a lingering doubt about the intellectual, scholarly, and ethical viability of taking an interest in Jung. Even so, in these pages, I shall argue that there is more to the question of Jung and Freud’s psychoanalysis than the oft-repeated story of two wrestling men. Over the past decade, there has been increasing clinical and academic interest in analytical psychology in non-Jungian circles, in spite of the fact that its core texts are not effectively represented on official reading lists and curriculum descriptions. Outside of this interest, though, Jung is mentioned primarily as an important schismatic in the history of psychoanalysis and not as a contributor worthy of sustained and systematic study in his own right. Although many psychoanalysts pass over his name in silence, many therapists – and not just Jungian – have “discovered” Jung to have been a major contributor to what appears now as cutting-edge new developments in clinical work. In this chapter, I shall suggest that Jung’s ideas merit a place in their own right in general clinical training in psychotherapy and in the contemporary academy. I shall also explain how I see the overall shape of the post-Jungian field via two classifications of the field into schools of
A Memetic Algorithm for 3D Protein Structure Prediction Problem

Memetic Algorithms are population-based metaheuristics intrinsically concerned with exploiting all available knowledge about the problem under study. The incorporation of problem domain knowledge is not an optional mechanism, but a fundamental feature of the Memetic Algorithms. In this paper, we present a Memetic Algorithm to tackle the three-dimensional protein structure prediction problem. The method uses a structured population and incorporates a Simulated Annealing algorithm as a local search strategy, as well as ad-hoc crossover and mutation operators to deal with the problem. It takes advantage of structural knowledge stored in the Protein Data Bank, by using an Angle Probability List that helps to reduce the search space and to guide the search strategy. The proposed algorithm was tested on 19 protein sequences of amino acid residues, and the results show the ability of the algorithm to find native-like protein structures. Experimental results have revealed that the proposed algorithm can find good solutions regarding root-mean-square deviation and global distance total score test in comparison with the experimental protein structures. We also show that our results are comparable in terms of folding organization with state-of-the-art prediction methods, corroborating the effectiveness of our proposal.
On the Road with an Autonomous Passenger Shuttle: Integration in Public Spaces

The integration of autonomous vehicles (AVs) onto public roads presents both technical and social challenges. Public understanding and acceptance of AVs requires engagement with people who live in, work at or visit cities where they are deployed on public road networks. We investigate the impact of one of the first placements of AV passenger transport on public roadways: the Sion "SmartShuttle". This late-breaking research presents preliminary results from interviews with local shopkeepers, residents, pedestrians and drivers to understand their attitudes and opinions of the shuttle. We also discuss video-based fieldwork that demonstrates how drivers negotiate next moves with one another through their windscreens using embodied signals such as gestures, lip-reading, and head nods to coordinate and manage a traffic situation. Finally, we consider the implications for how fully autonomous vehicles might be designed to take into account the subtle negotiations that road users engage in to coordinate with one another.
Evaluating Coincident Relationships Between Obesity Incidence and Normal Weight Incidence From Birth Through Kindergarten for US Children

Purpose: We examine the concurrent relationship between obesity incidence and normal weight status incidence and prevalence in children between 9 months and kindergarten. Design: Multistage, probability sample from the Early Childhood Longitudinal Study–Birth cohort. Setting: United States. Participants: Representative sample of US preschool children (n = 9950) followed from birth through kindergarten. Measures: From direct, anthropometric measures, we reported prevalence and incidence rates across 4 follow-up periods. Analysis: In addition to prevalence and incidence rates, we reported risk ratios based on multiple definitions and estimated predicted probabilities of obesity and normal weight status using clinically meaningful body mass index (BMI)-for-age percentiles. Results: Obesity prevalence (13%-20%) was much smaller than normal weight status prevalence (66%-70%). Lower socioeconomic status, Hispanic, and non-Hispanic black children had greater risk of obesity. During 9 months to kindergarten, obesity incidence decreased two-thirds (15.6%), while normal weight status incidence decreased almost one-half (44.6%). Coincidently, normal weight status incidence (ranged from 23% to 45%) was consistently and substantially higher than obesity incidence (ranged from 5% to 15%). During 4 years to kindergarten, the obesity risk for overweight children was 13 times higher than that for normal weight status children. Conclusion: Overall rates of obese and normal weight incidence were substantial at 9 months, trended lower, but remained high through kindergarten. At 4 years to kindergarten, children with relatively high initial BMI were very likely to become obese but far less likely to achieve normal weight status.
The Role of Arboreal Seed Dispersal Groups on the Seed Rain of a Lowland Tropical Forest 1

Most tropical plants produce fleshy fruits that are dispersed primarily by vertebrate frugivores. Behavioral disparities among vertebrate seed dispersers could influence patterns of seed distribution and thus forest structure. This study investigated the relative importance of arboreal seed dispersers and seed predators on the initial stage of forest organization–seed deposition. We asked the following questions: (1) To what degree do arboreal seed dispersers influence the species richness and abundance of the seed rain? and (2) Based on the plant species and strata of the forest for which they provide dispersal services, do arboreal seed dispersers represent similar or distinct functional groups? To answer these questions, seed rain was sampled for 12 months in the Dja Reserve, Cameroon. Seed traps representing five percent of the crown area were erected below the canopies of 90 trees belonging to nine focal tree species: 3 dispersed by monkeys, 3 dispersed by large frugivorous birds, and 3 wind‐dispersed species. Seeds disseminated by arboreal seed dispersers accounted for ca 12 percent of the seeds and 68 percent of the seed species identified in seed traps. Monkeys dispersed more than twice the number of seed species than large frugivorous birds, but birds dispersed more individual seeds. We identified two distinct functional dispersal groups, one composed of large frugivorous birds and one composed of monkeys, drop dispersers, and seed predators. These groups dispersed plants found in different canopy strata and exhibited low overlap in the seed species they disseminated. We conclude it is unlikely that seed dispersal services provided by monkeys could be compensated for by frugivorous birds in the event of their extirpation from Afrotropical forests.
Circularly Polarized Crossed Dipole on an HIS for 2.4/5.2/5.8-GHz WLAN Applications

A triband circularly polarized (CP) crossed-dipole antenna is introduced for 2.4/5.2/5.8-GHz wireless local area network (WLAN) applications. It employs a single feed and only two crossed trident-shaped dipoles as the primary radiating elements. To achieve a compact radiator size, two techniques are utilized, namely, insertion of a meander-line segment in the middle branch of the tridents and termination of all trident arms with arrowhead-shaped tips. The crossed trident-shaped dipoles are backed by a high impedance surface (HIS) to achieve a broadband characteristic and unidirectional radiation pattern at three bands. The measured impedance bandwidths, based on the -10-dB reflection coefficient values, are 2.21-2.62 GHz (410 MHz), 5.02-5.44 GHz (420 MHz), and 5.62-5.96 GHz (340 MHz), and the measured 3-dB axial-ratio bandwidths are 2.34-2.58 GHz (240 MHz), 5.14-5.38 GHz (240 MHz), and 5.72-5.88 GHz (160 MHz). The proposed antenna exhibits right-hand circular-polarized radiation with high gain.
Allosteric activation of pyruvate kinase via NAD+ in rat liver cells.

In isolated rat hepatocytes, it has previously been reported that a rise in the ATP content induces a proportional increase in cytosolic NAD+ concentration [Devin, A. , Guérin, B. & Rigoulet, M. (1997) FEBS Lett. 410, 329-332]. This occurs under physiological conditions such as various substrates or different energetic states. To investigate the effect of a physiological rise in cytosolic [NAD+] per se on glycolysis and gluconeogenesis, an increase in [NAD+] induced by exogenous nicotinamide addition was obtained without a change in redox potential, ATP/ADP ratio and ATP concentration. Using dihydroxyacetone as substrate, we found that an increase in cytosolic [NAD+] decreases gluconeogenesis and enhances glycolysis without significant alteration of dihydroxyacetone consumption rate. These modifications are the consequence of an allosteric activation of pyruvate kinase via cytosolic NAD+ content. Thus, in addition to the well-known thermodynamic control of glycolysis by pyridine-nucleotide redox status, our study points to a new mechanism of glycolytic flux regulation by NAD+ concentration at the level of pyruvate kinase activity.
Modified sequential k‐means clustering by utilizing response: A case study for fashion products

Modified sequential k‐means clustering concerns a k‐means clustering problem in which the clustering machine utilizes output similarity in addition. While conventional clustering methods commonly recognize similar instances at features‐level modified sequential clustering takes advantage of response, too. To this end, the approach we pursue is to enhance the quality of clustering by using some proper information. The information enables the clustering machine to detect more patterns and dependencies that may be relevant. This allows one to determine, for instance, which fashion products exhibit similar behaviour in terms of sales. Unfortunately, conventional clustering methods cannot tackle such cases, because they handle attributes solely at the feature level without considering any response. In this study, we introduce a novel approach underlying minimum conditional entropy clustering and show its advantages in terms of data analytics. In particular, we achieve this by modifying the conventional sequential k‐means algorithm. This modified clustering approach has the ability to reflect the response effect in a consistent manner. To verify the feasibility and the performance of this approach, we conducted several experiments based on real data from the apparel industry.
Testing Untyped Alleles (TUNA)—applications to genome‐wide association studies

The large number of tests performed in analyzing data from genome‐wide association studies has a large impact on the power of detecting risk variants, and analytic strategies specifying the optimal set of hypotheses to be tested are necessary. We propose a genome‐wide strategy that is based on one degree of freedom tests for all the genotyped variants, and for all the untyped variants for which there is sufficient information in the observed data. The set of untyped variants to be tested is found using multi‐locus measures of linkage disequilibrium and haplotype frequencies from a reference database such as HapMap (The International HapMap Consortium [2003] Nature 426:789–796). We introduce a novel statistic for testing differences in allele frequencies for untyped variation that is based on linear combinations of estimable haplotype frequencies. Algorithms for finding the sets of genotyped markers to be used in testing an untyped allele, and ways of incorporating haplotypes observed in the study data but not in the reference database are also described. The proposed testing strategy can be used as the first step in the analysis of genome‐wide association data, and, because every performed test is directed to a marker, it can be used to specify the set of polymorphisms to genotype in follow‐up studies. The described methodology provides also a tool for joint analysis of data from studies done on different platforms. Genet. Epidemiol. 2006. © 2006 Wiley‐Liss, Inc.
A SPECIFIC REVERSIBLE INHIBITION OF BACTERIOPHAGE T2

With most phages, the titer of a lysate measured by plaque count remains stable from the time of lysis or shows a progressive decrease as phage becomes inactivated by a variety of environmental agents. Freshly prepared lysates of bacteriophage T2 of Escherichia coli rise in titer spontaneously with time, the maxmum titer being reached in several weeks under refrigeration. Bertani (unpublished data, 1950) noted that this rise could be accelerated greatly by diluting a lysate in distilled water or by adding ZnSO4 to a final concentration of one per cent. Watson (personal communication, 1951) observed that lysates of T2 to which antibacterial serum was added before lysis did not show any rise in titer after dilution in distilled water. This suggested that normal lysates contained a certain proportion of particles that are prevented from forming plaques because of combination with specific host materials. The present paper provides evidence of the occurrence of such combination and of the properties of the combined phage.
Inhibitors of nitric oxide synthase attenuate nerve growth factor‐mediated increases in choline acetyltransferase expression in PC12 cells

NGF can regulate nitric oxide synthase (NOS) expression and nitric oxide (NO) can modulate NGF‐mediated neurotrophic responses. To investigate the role of NO in NGF‐activated expression of cholinergic phenotype, PC12 cells were treated with either the nonselective NOS inhibitor l‐NAME (N ω‐nitro‐l‐arginine methylester) or the inducible NOS selective inhibitor MIU (s‐methylisothiourea), and the effect on NGF‐stimulated ChAT mRNA levels and ChAT specific activity was determined. NGF increased steady‐state levels of mRNA and protein for both inducible and constitutive isozymes of NOS in PC12 cells, and led to enhanced NOS activity and NO production. MIU and, to a lesser extent, l‐NAME blocked neurite outgrowth in nerve growth factor (NGF)‐treated PC12 cells. Both l‐NAME and MIU attenuated NGF‐mediated increases in choline transferase (ChAT)‐specific activity and prevented the increase in expression of ChAT mRNA normally produced by NGF treatment of PC12 cells. The present study indicates that NO may be involved in the modulation of signal transduction pathways by which NGF leads to increased ChAT gene expression in PC12 cells.
ANTIMICROBIAL ACTIVITY OF FERMENTED GREEN TEA LIQUID

Green tea kombucha made of sugar and single yeast was investigated for its antimicrobial activity and composition changes during fermentation. Individual and total tea polyphenols, caffeine, sucrose, reducing sugar, total sugar, pH, acetic acid and total acids, ethanol concentration, superoxide dismutase and hexokinase activities, yeast yield and antimicrobial activity were measured systematically at the intervals of 12 to 24 hours of fermentation. Results shown that a 36-hour sample had total growth inhibition on Escherichia coli and Staphylococcus aureus, but almost no effects on Bifidobacterium and Lactobacillus delbrueckii subspecies bulgaricus. In order to see the effects of the main components on the microbial growth, a mixture of tea polyphenols, a mixture of acids and ethanol were tested respectively and showed various degrees of antimicrobial activities which were much less than the activity of the 36-hour kombucha, suggesting that there was a synergy effect among the components.
Neutrophils: key mediators of tumour angiogenesis

It is now well known that most malignant tumours contain a significant amount of leucocytic infiltrates the presence of which has, on many occasions, been linked to poor patient prognosis. These leucocyte populations are recruited to tumours by chemotactic factors released by either viable or necrotic tumour cells, or by cells within the tumour stroma. In recent times, most studies have analysed the role that tumour‐associated macrophages (TAM) have on tumour progression. However, there is now increasing evidence to show that neutrophils also actively participate in this process. Whilst there are some data to suggest that neutrophil‐derived factors can promote genetic mutations leading to tumourigenesis, or secrete factors that promote tumour cell proliferation; there is now substantial evidence to show that neutrophils, like TAM, significantly affect tumour angiogenesis. In this review, we discuss the likely mechanisms by which neutrophils are recruited into the tumour and then elaborate on how these cells may induce tumour vascularization by the secretion of powerful pro‐angiogenic factors. We also discuss possible future chemotherapeutic strategies that are aimed at limiting tumour angiogenesis by inhibiting neutrophil recruitment.
Lipoprotein(a), measured with an assay independent of apolipoprotein(a) isoform size, and risk of future cardiovascular events among initially healthy women.

CONTEXT Controversy exists as to whether lipoprotein(a), a lipoprotein with homology to plasminogen, is a clinically meaningful cardiovascular risk marker in women. There is also poor agreement among lipoprotein(a) levels obtained by different assays. OBJECTIVE To determine the association of lipoprotein(a) levels, measured with an assay independent of apolipoprotein(a) isoform size, with the incidence of future cardiovascular events. DESIGN, SETTING, AND PARTICIPANTS Prospective study of 27,791 initially healthy women in the Women's Health Study, enrolled between November 1992 and July 1995 and followed up for 10 years. Lipoprotein(a) level was measured in blood samples obtained at baseline with an assay independent of apolipoprotein(a) isoform size. MAIN OUTCOME MEASURE Hazard ratios (HRs) for first-ever major cardiovascular events (nonfatal myocardial infarction, nonfatal cerebrovascular event, coronary revascularization, or cardiovascular deaths). RESULTS During follow-up, there were 899 incident cardiovascular events. After adjusting for age, smoking, blood pressure, body mass index, total cholesterol, high-density lipoprotein cholesterol, diabetes, hormone use, C-reactive protein, and randomization treatment groups, women in the highest quintile of lipoprotein(a) (> or =44.0 mg/dL) were 1.47 times more likely (95% CI, 1.21-1.79; P for trend <.001) to develop cardiovascular events than women in the lowest quintile (< or =3.4 mg/dL). This association, however, was due almost entirely to a threshold effect among those with the highest lipoprotein(a) levels. After adjusting for all of the variables listed above, the HR associated with lipoprotein(a) levels exceeding the 90th percentile (> or =65.5 mg/dL) was 1.66 (95% CI, 1.38-1.99); 95th percentile (> or =83 mg/dL), 1.87 (95% CI, 1.50-2.34); and 99th percentile (> or =130.7 mg/dL), 1.99 (95% CI, 1.32-3.00), with almost no risk gradient at lower levels. Associations were strongest among women with low-density lipoprotein cholesterol (LDL-C) above the median level. In this subgroup, the adjusted HR associated with lipoprotein(a) levels exceeding the 90th percentile was 1.81 (95% CI, 1.48-2.23); 95th percentile, 1.93 (95% CI, 1.51-2.48); and 99th percentile, 1.93 (95% CI, 1.21-3.05) (P value for interaction with LDL-C = .001). CONCLUSIONS In this cohort of initially healthy women, extremely high levels of lipoprotein(a) (> or =90th percentile), measured with an assay independent of apolipoprotein(a) isoform size, were associated with increased cardiovascular risk, particularly in women with high levels of LDL-C. However, the threshold and interaction effects observed do not support routine measurement of lipoprotein(a) for cardiovascular stratification in women.
Augmented reality for skill transfer in assembly task

In this research, an augmented reality is proposed to enhance the skill transfer in the assembly task. In this system, a user can see the additional graphics information superimposed on the real world scenes. Graphical instructions and virtual objects are used for advising the user with the assembly steps and the targeted positions in assembly task. Furthermore, the system's judgment component can guide the user for the sequences of assembly and check whether the user performs actions correctly. The experimental results show that the training system with augmented reality has high percentages of transferability and high transfer effectiveness ratio. The system can also reduce assembly completion times and the number of assembly steps. Moreover, the questionnaire results show that the users are very satisfied with this kind of system. Therefore, the training system embedded with an augmented reality would be a new trend to improve the user's skills.
Effects of the scaffold proteins liprin‐α1, β1 and β2 on invasion by breast cancer cells

The expression of the scaffold protein liprin‐α1 is upregulated in human breast cancer. This protein is part of a molecular network that is important for tumour cell invasion in vitro. Liprin‐α1 promotes invasion by supporting the protrusive activity at the leading edge of the migrating tumour cell and the degradation of the extracellular matrix by invadopodia. In this study, we have addressed the role of liprin‐α1 in the invasive process in vivo and of liprin‐proteins in tumor cell motility.
Cogging torque optimization of a four-pole PM machine

This paper presents a finite element based optimization study of a four-pole permanent magnets machine. The purpose of the analysis is to find a constructive solution characterized by a cogging torque less than 1% of the rated torque of the reference machine and reduced e.m. f. harmonics. The elements that are modified during the optimization process are the cross-section geometrical parameters of the permanent magnets and of the rotor core by keeping unchanged the magnets volume and stator geometry. Several constructive measures were studied, the best one being deeper analyzed. The numerical analysis is based on 2D magneto-static and transient magnetic type finite element models of the machine. Some of the numerical results are validated by experimental measurements.