Miracle-dz/UniFAR-FTUs huggingface dataset:
Illness Severity and Work Productivity Loss Among Working Adults With Medically Attended Acute Respiratory Illnesses: US Influenza Vaccine Effectiveness Network 2012-2013.

BACKGROUND Influenza causes significant morbidity and mortality, with considerable economic costs, including lost work productivity. Influenza vaccines may reduce the economic burden through primary prevention of influenza and reduction in illness severity. METHODS We examined illness severity and work productivity loss among working adults with medically attended acute respiratory illnesses and compared outcomes for subjects with and without laboratory-confirmed influenza and by influenza vaccination status among subjects with influenza during the 2012-2013 influenza season. RESULTS Illnesses laboratory-confirmed as influenza (ie, cases) were subjectively assessed as more severe than illnesses not caused by influenza (ie, noncases) based on multiple measures, including current health status at study enrollment (≤7 days from illness onset) and current activity and sleep quality status relative to usual. Influenza cases reported missing 45% more work hours (20.5 vs 15.0; P < .001) than noncases and subjectively assessed their work productivity as impeded to a greater degree (6.0 vs 5.4; P < .001). Current health status and current activity relative to usual were subjectively assessed as modestly but significantly better for vaccinated cases compared with unvaccinated cases; however, no significant modifications of sleep quality, missed work hours, or work productivity loss were noted for vaccinated subjects. CONCLUSIONS Influenza illnesses were more severe and resulted in more missed work hours and productivity loss than illnesses not confirmed as influenza. Modest reductions in illness severity for vaccinated cases were observed. These findings highlight the burden of influenza illnesses and illustrate the importance of laboratory confirmation of influenza outcomes in evaluations of vaccine effectiveness.
Production and characterization of monoclonal antibodies to four Egtved virus structural proteins.

With the aim of studying molecular mechanisms of virulence and immunogenesis of Egtved virus, monoclonal antibodies (MAbs) were produced against 4 dominant virus proteins (G, N, M, and M2). The reactivity of each MAb was determined by ELISA, immunoblotting, immunofluorescence and plaque neutralization. Antibodies specific for each of the 4 proteins, as demonstrated by immunoblotting, gave characteristic reactions in ELISA as well as immunofluorescence. None of the MAbs were able to neutralize virus in vitro. When analysed in immunofluorescence using cell cultures fixed at different times after inoculation with live virus, the N-protein was first to be detected followed by M,, G and M2. G-specific MAbs reacted with either a 'reticular', or a 'Go1gi'-form of the G-protein. Results are consistent with published information on the protein compositon and cellular appearance pattern of other rhabdovimses studied in vitro.
Evidence-based Series 9-9 EDUCATION AND INFORMATION 2012 Malignant Extradural Spinal Cord Compression : Diagnosis and Management

Report Date: January 2004 An assessment conducted in December 2012 put Evidence-based Series (EBS) 9-9 in the Education and Information section. This means that the recommendations will no longer be maintained but may still be useful for academic or other information purposes. The PEBC has a formal and standardized process to ensure the currency of each document (PEBC Assessment & Review Protocol).
Megastigmus seed chalcids (Hymenoptera, Torymidae) radiated much more on Angiosperms than previously considered. I- Description of 8 new species from Kenya, with a key to the females of Eastern and Southern Africa

Abstract A survey of seed chalcids from woody plants in Kenya revealed 12 species belonging to the genus Megastigmus Dalman, 1820, and has increased to 16 the number of Megastigmus species presently recorded from the Afrotropical Region, of which at least 13 are seed feeders. A key to female Megastigmus of the Afrotropical Region is provided. Eight new species are described from morphological evidence: Megastigmus lanneae Roques & Copeland, Megastigmus laventhali Roques & Copeland, Megastigmus ozoroae Roques & Copeland, and Megastigmus smithi Roques & Copeland in seeds of species of the family Anacardiaceae, Megastigmus copelandi Roques & Copeland and Megastigmus grewianae Roques & Copeland in seeds of Malvaceae, Megastigmus helinae Roques & Copeland in seeds of Rhamnaceae, and Megastigmus icipeensis Roques & Copeland for which no host is known. These collections include the first records of Malvaceae and Rhamnaceae as hosts of Megastigmus seed chalcids, which appear to have radiated in Angiosperms much more than previously considered. Analyses of the mitochondrial ( cytochrome oxidase subunit one – COI) and nuclear DNA (28S ribosomal region) could be carried out on 8 of the 16 African species of which 5 were newly described ones. The species associated with Anacardiaceae always clustered together in phylogenies, confirming the existence of a strong and ancestral monophyletic clade, unlike the ones associated with Malvaceae and Rhamnaceae, whose position remains unclear. All holotypes are deposited in the National Museums of Kenya.
Analysis of airway epithelial regeneration and repair following endobronchial brush biopsy in sheep

ABSTRACT Understanding the fundamental processes involved in repairing the airway wall following injury is fundamental to understanding the way in which these processes are perturbed during disease pathology. Indeed complex diseases such as asthma and chronic obstructive pulmonary disease (COPD) have at their core evidence of airway wall remodeling processes that play a crucial functional role in these diseases. The authors sought to understand the dynamic cellular events that occur during bronchial airway epithelial repair in sheep. The injury was induced by endobronchial brush biopsy (BBr), a process that causes epithelial débridement and induces a consequential repair process. In addition, the current experimental protocol allowed for the time-dependent changes in airway wall morphology to be studied both within and between animals. The initial débridement was followed by evidence of dedifferentiation in the intact epithelium at the wound margins, followed by proliferation of cells both within the epithelium and in the deeper wall structures, notably in association with the submucosal glands and smooth muscle bundles. Seven days after injury, although the airway wall was thickened at the site of damage, the epithelial layer was intact, with evidence of redifferentiation. These studies, in demonstrating broad agreement with previous studies in small animals, indicate the wider relevance of this system as a comparative model and should provide a solid basis upon which to further characterize the critical cellular and molecular interactions that underlie both effective restitution and pathological repair.
Contribution of Traffic to PM2.5 Exposure: 30%—or Even Considerably More?

From a public health, epidemiology, exposure, and risk assessment perspective, there is high interest for personal exposure as the ultimate health relevant measure. Furthermore, policy makers need source specific personal exposure data. However, personal exposure assessment is usually not feasible on a large scale; thus, we will continue to rely on proxy measures and modeling. Boudet et al. developed an interesting and new approach to address the question regarding traffic related personal exposure to PM2.5 (Boudet et al., 2000). They made use of EXPOLIS, the first study in Europe to assess population-based data on personal, home indoor, home outdoor, and workplace exposure to fine particulate, PM2.5, CO, and VOC (Jantunen et al., 1998). The study included time-microenvironment-activity diaries, which are much easier to apply. Instead of using personal PM2.5 measurements, Boudet et al. developed a statistical model, based on fixed-site monitor data and EXPOLIS-Grenoble time-activity diary information (Boudet et al., 2000). The key exposure-relevant measure of their model is proximity to traffic, defined as the time spent close to (or in) traffic. The main model assigned 30% of personal PM2.5 exposure to traffic. The advantage of their approach is obvious: It can rely on available monitoring data and a rather small sample of time-activity data, which can be easily collected. The disadvantage of modeling is the reliance on a variety of assumptions, which may influence the final results. Thus, we may ask: Does the Boudet model overestimate the impact of traffic, or is it more likely to be a prudent estimate of the contribution of traffic? Three inherent assumptions of the model favor a prudent result:
Envejecimiento activo y reserva cognitiva: guía para la evaluación y la estimulación

En la linea de las declaraciones de diferentes organismos internacionales (OMS) e instituciones y es­tamentos profesionales, se hace necesario avanzar en la concrecion de estrategias para promocionar el envejecimiento activo o saludable. Uno de los parametros que aparece como mas relevante en la litera­tura es el de reserva cognitiva, objeto central de este trabajo. Se propone una guia fundamentada para la evaluacion asi como unas lineas generales de programas que estimulen esta variable amortiguadora del declive o del deterioro en poblacion mayor.
Coordination of Pricing, Ordering, and Lead time Decisions in a Manufacturing Supply Chain

In this paper, an incentive policy is proposed to coordinate ordering, lead time, and pricing strategies in a two-echelon manufacturing supply chain (SC) consisting of one manufacturer and one retailer. The system is faced with a stochastic demand which depends on both price and lead time. The manufacturer decides on production size and manufacturing acceleration rate while the retailer determines the retail price and order size. A game-theory approach is proposed to analyze both members’ decision making process. An integrated decision making process where both members cooperate as a single entity aiming to maximize system-wide profit is formulated. Finally a coordination mechanism based on adjusting wholesale price is proposed to convince both members to decide jointly. Numerical experiments demonstrate that whole SC profitability as well as both members profitability is increased by applying the proposed scheme. Results indicate that coordinated decision making decreases both retail price and lead time length while it causes an increase in order size.
THE SIGNIFICANCE OF SERUM S 100 , MIA AND LDH IN CUTANEOUS MALIGNANT MELANOMA

Malignant melanoma is a disease with a continuously increasing incidence and an unfavorable outcome in stage IV. It is a tumor with intense metabolic activity that produces and releases in the blood stream enzymes, cytokines and growth factors. Although several proteins were suggested as serum markers in malignant melanoma, until now none has proven itself sensitive enough to be currently used in treatment monitoring and patient follow-up. The target of this paper is to synthesize the information from the literature referring to three of the most commonly used serum markers in malignant melanoma. With the exception of LDH, whose role is well established, MIA and S100B are still the subject of various studies.
Investigation of different acoustic modeling techniques for low resource Indian language data

In this paper, we investigate the performance of deep neural network (DNN) and Subspace Gaussian mixture model (SGMM) in low-resource condition. Even though DNN outperforms SGMM and continuous density hidden Markov models (CDHMM) for high-resource data, it degrades in performance while modeling low-resource data. Our experimental results show that SGMM outperforms DNN for limited transcribed data. To resolve this problem in DNN, we propose to train DNN containing bottleneck layer in two stages: First stage involves extraction of bottleneck features. In second stage, the extracted bottleneck features from first stage are used to train DNN having bottleneck layer. All our experiments are performed using two Indian languages (Tamil & Hindi) in Mandi database. Our proposed method shows improved performance when compared to baseline SGMM and DNN models for limited training data.
Multilingual opinion mining

Cada dia se genera gran cantidad de texto en diferentes medios online. Gran parte de ese texto contiene opiniones acerca de multitud de entidades, productos, servicios, etc. Dada la creciente necesidad de disponer de medios automatizados para analizar, procesar y explotar esa informacion, las tecnicas de analisis de sentimiento han recibido gran cantidad de atencion por parte de la industria y la comunidad cientifica durante la ultima decada y media. No obstante, muchas de las tecnicas empleadas suelen requerir de entrenamiento supervisado utilizando para ello ejemplos anotados manualmente, u otros recursos linguisticos relacionados con un idioma o dominio de aplicacion especificos. Esto limita la aplicacion de este tipo de tecnicas, ya que dicho recursos y ejemplos anotados no son sencillos de obtener. En esta tesis se explora una serie de metodos para realizar diversos analisis automaticos de texto en el marco del analisis de sentimiento, incluyendo la obtencion automatica de terminos de un dominio, palabras que expresan opinion, polaridad del sentimiento de dichas palabras (positivas o negativas), etc. Finalmente se propone y se evalua un metodo que combina representacion continua de palabras (continuous word embeddings) y topic-modelling inspirado en la tecnica de Latent Dirichlet Allocation (LDA), para obtener un sistema de analisis de sentimiento basado en aspectos (ABSA), que solo necesita unas pocas palabras semilla para procesar textos de un idioma o dominio determinados. De este modo, la adaptacion a otro idioma o dominio se reduce a la traduccion de las palabras semilla correspondientes.
Ant Colony Optimization (ACO) For The Traveling Salesman Problem (TSP) Using Partitioning

: An ant colony optimization is a technique which was introduced in 1990’s and which can be applied to a variety of discrete (combinatorial) optimization problem and to continuous optimization. The ACO algorithm is simulated with the foraging behavior of the real ants to find the incremental solution constructions and to realize a pheromone laying-and-following mechanism. This pheromone is the indirect communication among the ants. In this paper we introduces the partitioning technique based on the divide and conquer strategy for the traveling salesman problem ( which is one of the most important combinatorial problem) in which the original problem is partitioned into the group of sub problems. And then we apply the ant colony algorithm using candidate list strategy for each smaller sub problems. After that by applying the local optimization and combining the sub problems to find the good solution for the original problem by improving the exploration efficiency of the ants. At the end of this paper we have also be presented the comparison of result with the normal ant colony system for finding the optimal solution to the traveling salesman problem.
Directly modelling matched case-control data.

Matching in case-control studies is a situation in which one wishes to make inferences about a parameter of interest in the presence of nuisance parameters. The usual approach is to apply a conditional likelihood. A bivariate latent class log-linear model for binomial responses is shown to yield a standard likelihood identical to the usual conditional one. This extension of the Rasch model for binary responses gives consistent estimates and a suitable likelihood function for cases matched with any fixed number of controls.
La dervillite, Ag2AsS2, nouvelle définition de l'espèce

La dervillite a ete decrite en 1941 sur la base d'une etude goniometrique de minuscules cristaux (≤0,3 mm) et d'une analyse qualitative indiquant la presence de Pb, S et Sb, peut-etre aussi Bi. Un nouvel examen de l'echantillon type a montre que les donnees chimiques etaient fausses, et basees sur des essais qui n'ont manifestement pas ete menes sur des cristaux de dervillite, mais sur l'une ou l'autre poudre preparee pour des travaux aux rayons X. La confusion etait due aux circonstances particulieres causees par l'evacuation de l'Universite de Strasbourg en 1939, au cours de ces recherches sur la dervillite. Le specimen holotype de Sainte-Marie-aux-Mines (Haut-Rhin, France) (Mus. Nat. Hist. Nat. Paris, n° 1531) est le seul connu et contient quelques cristaux. Une etude de quatre d'entre eux a permis une redefinition complete de l'espece. L'etude goniometrique confirme les mesures effectuees sur un cristal en 1935 et son identite avec ceux qui ont servi a cette presente etude. La dervillite est monoclinique, P2/a, avec : a = 6,833 ; b = 12,932 ; c = 9,638A ; β = 99°33', en parfait accord avec les mesures goniometriques. Les principales raies du diagramme de poudre sont : 3,075 (10) 013 ; 3,019 (8) 201, -132 ; 2,843 (5) -141, 023 ; 3,251 (3) -211 ; 2,659 (3) 230. Le pouvoir reflecteur de la dervillite est un peu plus faible que celui du groupe de la tetraedrite. VHN 19,5 kg/mm2 pour un poids de 50-100 g. L'analyse a la microsonde donne : Ag = 61,39 %, As = 19,35 %, S = 18,06 %, ∑ = 98,48 % ; le deficit observe est probablement du a une perte en arsenic en raison de rechauffement sous le faisceau electronique. Pb, Sb et Bi n'ont pas ete detectes. Ces resultats conduisent a la formule Ag2AsS2. La densite n'a pu etre mesuree du fait du manque de produit. Sur la base de la formule Ag8As4S8 et Z = 2, d calc. is 5,62. Une etude de la structure est en cours. Le specimen holotype et une section contenant quelques cristaux sont conserves au Museum National d'Histoire Naturelle de Paris. Une autre section polie contenant un cristal de dervillite est conservee a l'Ecole Nationale Superieure des Mines de Paris.
Lipid Keratopathy in the Watanabe (WHHL) Rabbit

pofuscinosis in humans, ranging from an amorphous granular matrix to lamellated structures with curvilinear or fingerprint patterns.1° The caprine cytoplasmic granules most closely resemble those of the Spielmeyer-Sjogren type, in which laminated fingerprint profiles predominate.I0 There are also clinical similarities between the caprine disease and this form of the human disorder, in that both are of adolescent onset with slowly progressive deterioration of cerebral function. In contrast, the other forms of human neuronal lipofuscinosis are usually of earlier or later onset and may progress more rapidly.
The early development of immunity to Eimeria maxima in comparison with that to Eimeria tenella

Immunity to Eimeria maxima, judged by oocyst production resulting from a low challenge inoculum, was evident when the challenge was given as early as 3 days after the immunizing dose of 250 or 500 oocysts. Immunity was complete, i.e. no oocysts were produced, to challenge at 7 days after an initial inoculum of 500 oocysts, or at 14 days after 250 oocysts. Judged by the above criteria 250 oocysts of E. tenella did not induce immunity to challenge given at 3, 5, 7 or 14 days. The findings are discussed.
Correlation of Approximate Entropy, Bispectral Index, and Spectral Edge Frequency 95 (SEF95) with Clinical Signs of “Anesthetic Depth” during Coadministration of Propofol and Remifentanil

Background Several studies relating electroencephalogram parameter values to clinical endpoints using a single (mostly hypnotic) drug at relatively low levels of central nervous system depression (sedation) have been published. However, the usefulness of a parameter derived from the electroencephalogram for clinical anesthesia largely depends on its ability to predict the response to stimuli of different intensity or painfulness under a combination of a hypnotic and an (opioid) analgesic. This study was designed to evaluate the predictive performance of spectral edge frequency 95 (SEF95), BIS, and approximate entropy for the response to increasingly intense stimuli under different concentrations of both propofol and remifentanil in the therapeutic range. Methods Ten healthy male and ten healthy female volunteers were studied during coadministration of propofol and remifentanil. After having maintained a specific target concentration for 10 min, the depth of sedation–anesthesia was assessed using the responsiveness component of the Observer's Assessment of Alertness/Sedation (OAA/S) rating scale, which was modified by adding insertion of a laryngeal mask and laryngoscopy. The electroencephalogram derived parameters approximate entropy, bispectral index, and SEF95 were recorded just before sedation level was assessed. Results The prediction probability values for approximate entropy were slightly, but not significantly, better than those for bispectral index, SEF95, and the combination of drug concentrations. A much lower prediction ability was observed for tolerance of airway manipulation than for hypnotic endpoints. Conclusion Approximate entropy revealed informations on hypnotic and analgesic endpoints using coadministration of propofol and remifentanil comparable to bispectral index, SEF95, and the combination of drug concentrations.
Analysis of quasielastic light scattering in LiNbO3 near TC.

We have reexamined the Raman spectra of lithium tantalate from 294 to 1059 K with special emphasis upon the quasielastic scattering from 0\char21{}200 ${\mathrm{cm}}^{\mathrm{\ensuremath{-}}1}$. We show that the complete ${A}_{1}$-symmetry spectrum at each temperature, including both the lowest-energy optical phonon and the quasielastic scattering, can be fitted to the response function for a system with a relaxing self-energy ${\ensuremath{\chi}}^{\mathrm{\ensuremath{-}}1}$(\ensuremath{\omega},T)=${\ensuremath{\omega}}_{0}^{2}$(T)-\ensuremath{\omega} $^{2}$-i\ensuremath{\omega}\ensuremath{\gamma}(T)-${\ensuremath{\delta}}^{2}$(T)/[1-i\ensuremath{\omega}\ensuremath{\tau}(T)] and that the fitting parameters vary monotonically with temperature. In agreement with recent analysis of ${\mathrm{LiNbO}}_{3}$ [Okamoto, Wang, and Scott, Phys. Rev. B 32, 6787 (1985)] we find that the linewidth \ensuremath{\gamma} for the lowest energy ${A}_{1}$ phonon increases rapidly with temperature, from 27 ${\mathrm{cm}}^{\mathrm{\ensuremath{-}}1}$ at 294 K to 382 ${\mathrm{cm}}^{\mathrm{\ensuremath{-}}1}$ very near ${T}_{C}$; \ensuremath{\tau} exhibits a critical slowing down from 0.50 ps far from ${T}_{C}$ to 2.6 ps at ${T}_{C}$ and continues to increase above ${T}_{C}$ (5.3 ps at 1059 K); the lowest-energy optical phonon ``softens'' only slightly, from ${\ensuremath{\omega}}_{0}$ of 202 ${\mathrm{cm}}^{\mathrm{\ensuremath{-}}1}$ at 294 K to 178 ${\mathrm{cm}}^{\mathrm{\ensuremath{-}}1}$ at ${T}_{C}$=881 K (determined from the dielectric constant), and that the coupling constant ${\ensuremath{\delta}}^{2}$(T) increases supralinearly with temperature, as in ${\mathrm{LiNbO}}_{3}$.