Miracle-dz/UniFAR-FTUs huggingface dataset:
Spatiotemporal Discovery: Appearance + Behaviour = Agent

Experiments in infant category formation indicate a strong role for temporal continuity and change in perceptual categorization. Computational approaches to model discovery in vision have traditionally focused on static images, with appearance features such as shape playing an important role. In this work, we consider integrating agent behaviours with shape for the purpose of agent discovery. Improved algorithms for video segmentation and tracking under occlusion enable us to construct models that characterize agents in terms of motion and interaction with other objects. We present a preliminary approach for discovering agents based on a combination of appearance and motion histories. Using uncalibrated camera images, we characterize objects discovered in the scene by their shape and motion attributes, and cluster these using agglomerative hierarchical clustering. Even with very simple feature sets, initial results suggest that the approach forms reasonable clusters for diverse categories such as people, and for very distinct clusters (animals), and performs above average on other classes.
High energy emission and polarisation limits for the INTEGRAL burst GRB 061122

Context. GRB061122 is one of the brightest GRBs detected within INTEGRAL's field of view to date, with a peak flux (20-200 keV) of 32 photons cm(-2) s(-1) and fluence of 2 x 10(-5) erg cm(-2). The Spectrometer aboard INTEGRAL, SPI, can measure linear polarisation in bright GRBs through the process of Compton scattering in the Germanium detectors. Polarisation measurements of the prompt emission are relatively rare. The spectral and polarisation results can be combined to provide vital information about the circumburst region. Aims. The two gamma-ray detectors on INTEGRAL were used to investigate the spectral characteristics of GRB061122. A search for linear polarisation in the prompt emission was carried out on GRB061122 using the SPI multiple event data in the energy range 100 keV-1 MeV. The X-ray properties were examined using data from the X-Ray Telescope (XRT) on Swift. Methods. The gamma-ray spectral and temporal properties of GRB061122 were determined using IBIS and SPI. The afterglow properties were obtained using XRT. The multiple event data of GRB061122 from SPI were analysed and compared with the predicted instrument response obtained from Monte-Carlo simulations using the GEANT 4 INTEGRAL mass model. The chi(2) distributions between the real and simulated data as a function of the percentage polarisation and polarisation angle were calculated and limits on the level and angle of polarisation were obtained from the best-fit value of chi(2). Results. The prompt spectrum was best fit by a combination of a blackbody and a power-law model (the quasithermal model), with evidence for high energy emission continuing above 8 MeV. A pseudo-redshift value of pz = 0.95 +/- 0.18 was determined using the spectral fit parameters. The isotropic energy at this pseudo-redshift is 8.5 x 10(52) erg. The jet opening angle was estimated to be smaller than 2.8 degrees or larger than 11.9 degrees from the X-ray lightcurve. An upper limit of 60% polarisation was determined for the prompt emission of GRB061122, using the multiple event data from the spectrometer on INTEGRAL. Conclusions. The high energy emission observed in the spectrum may be due to the reverse shock interacting with the GRB ejecta when it is decelerated by the circumburst medium. This behaviour has been observed in a small fraction of GRBs to date, but is expected to be more commonly observed by the Fermi Gamma-ray Space Telescope. The conditions for polarisation are met if the jet opening angle is less than 2.8 degrees, but further constraints on the level of polarisation are not possible.
Positive Psychology Group Intervention for Breast Cancer Patients: A Randomised Trial

This study assessed the effects of a psychological group intervention based on positive psychology in women with breast cancer. 175 women were randomly assigned either to an experimental group, receiving the 14-session intervention (n = 87), or to a waitlist group (n = 88) that did not receive any type of intervention. For treatment, a group intervention was applied, based on improving psychological strengths and enhancing positive psychology-based styles of coping. Strength-related outcomes, self-esteem, well-being, and happiness were assessed before and after the intervention. The experimental group showed higher scores on all of the study variables after the intervention. Participants reported improved self-esteem, emotional intelligence-related abilities, resilience, and optimism, as well as positive affectivity, well-being, and happiness. The results show a beneficial effect of this psychological intervention based on positive psychology on female breast cancer patients' psychological health.
Phylogenies and the Comparative Method

Comparative studies of the relationship between two phenotypes, or between a phenotype and an environment, are frequently carried out by invalid statistical methods. Most regression, correlation, and contingency table methods, including nonparametric methods, assume that the points are drawn independently from a common distribution. When species are taken from a branching phylogeny, they are manifestly nonindependent. Use of a statistical method that assumes independence will cause overstatement of the significance in hypothesis tests. Some illustrative examples of these phenomena have been given, and limitations of previous proposals of ways to correct for the nonindependence have been discussed. A method of correcting for the phylogeny has been proposed. It requires that we know both the tree topology and the branch lengths, and that we be willing to allow the characters to be modeled by Brownian motion on a linear scale. Given these conditions, the phylogeny specifies a set of contrasts among species, contrasts that are statistically independent and can be used in regression or correlation studies. The considerable barriers to making practical use of this technique have been discussed.
The Search for Enlightenment - The Working Class and Adult Education in the Twentieth Century

Contents Foreword Jack Jones Introduction Brian Simon Part 1. 1909 - 1945 The struggle for hegemony, 1920-1926 Brian Simon The spark of independent working class education Edmund and Ruth Frow The Labour College movement between the wars: national and north-west developments Margaret Cohen Revolutionary education revived: the communist challenge to the Labour Colleges, 1925-1944 Margaret Cohen Bouts of suspicion: political controversies in adult education, 1925-1944 Roger Fieldhouse Part 2. 1945-1988 The demise of the national council of Labour Colleges John McIlroy The triumph of technical training? John McIlroy Trade union education for a change John McIlroy The challenge to working class education Bob Fryer Notes on contributors Index
The Stanford Dash multiprocessor

The overall goals and major features of the directory architecture for shared memory (Dash) are presented. The fundamental premise behind the architecture is that it is possible to build a scalable high-performance machine with a single address space and coherent caches. The Dash architecture is scalable in that it achieves linear or near-linear performance growth as the number of processors increases from a few to a few thousand. This performance results from distributing the memory among processing nodes and using a network with scalable bandwidth to connect the nodes. The architecture allows shared data to be cached, significantly reducing the latency of memory accesses and yielding higher processor utilization and higher overall performance. A distributed directory-based protocol that provides cache coherence without compromising scalability is discussed in detail. The Dash prototype machine and the corresponding software support are described. <<ETX>>
Strategic Modelling of Web Information Systems and its Impact on Visual Design Patterns ∗

The development of web information systems (WISs) requires modelling on various layers of abstraction. Based on an abstract abstraction layer model (ALM) the work in this paper approaches the modelling on the highest layer dealing with strategic modelling. Strategic modelling addresses a very general characterisation of WISs in terms of its content, functionality, context, usage and presentation. The paper discusses branding, utilisation space modelling, utilisation portfolio modelling and atmosphere modelling as the major parts of a strategic model. In a second step it is then shown how the strategic model impacts on the formation of a WIS in terms of its layout and playout.
A stepped wedge cluster randomized control trial of dried blood spot testing to improve the uptake of hepatitis C antibody testing within UK prisons

Background: The prevalence of hepatitis C (HCV) is elevated within prison populations, yet diagnosis in prisons remains low. Dried blood spot testing (DBST) is a simple procedure for the detection of HCV antibodies; its impact on testing in the prison context is unknown. Methods: We carried out a stepped-wedge cluster-randomized control trial of DBST for HCV among prisoners within five male prisons and one female prison. Each prison was a separate cluster. The order in which the intervention (training in use of DBST for HCV testing and logistic support) was introduced was randomized across clusters. The outcome measure was the HCV testing rate by prison. Imputation analysis was carried out to account for missing data. Planned and actual intervention times differed in some prisons; data were thus analysed by intention to treat (ITT) and by observed step times. Results: There was insufficient evidence of an effect of the intervention on testing rate using either the ITT intervention time (OR: 0.84; 95% CI: 0.68–1.03; P = 0.088) or using the actual intervention time (OR: 0.86; 95% CI: 0.71–1.06; P = 0.153). This was confirmed by the pooled results of five imputed data sets. Conclusions: DBST as a stand-alone intervention was insufficient to increase HCV diagnosis within the UK prison setting. Factors such as staff training and allocation of staff time for regular clinics are key to improving service delivery. We demonstrate that prisons can conduct rigorous studies of new interventions, but data collection can be problematic. Trial registration: International Standard Randomized Controlled Trial Number Register (ISRCTN number ISRCTN05628482).
Real-time 3D reconstruction and pose estimation for human motion analysis

In this paper, we present a markerless 3D motion capture system based on a volume reconstruction technique of non rigid bodies. It depicts a new approach for pose estimation in order to fit an articulated body model into the captured real-time information. We aim at analyzing athlete's movements in real-time within a 3D interactive graphics system. The paper addresses recent trends in vision based analysis and its fusion with 3D interactive computer graphics. Hence, the proposed system presents new methods for the 3D reconstruction of human body parts from calibrated multiple cameras based on voxel carving techniques and a 3D pose estimation methodology using Pseudo-Zernike Moments applied to an articulated human body model. Several algorithms have been designed for the deployment within a GPGPU environment allowing us to calculate several principle process steps from segmentation and reconstruction to volume optimization in real-time.
Advantages and Pitfalls of Mass Spectrometry Based Metabolome Profiling in Systems Biology

Mass spectrometry-based metabolome profiling became the method of choice in systems biology approaches and aims to enhance biological understanding of complex biological systems. Genomics, transcriptomics, and proteomics are well established technologies and are commonly used by many scientists. In comparison, metabolomics is an emerging field and has not reached such high-throughput, routine and coverage than other omics technologies. Nevertheless, substantial improvements were achieved during the last years. Integrated data derived from multi-omics approaches will provide a deeper understanding of entire biological systems. Metabolome profiling is mainly hampered by its diversity, variation of metabolite concentration by several orders of magnitude and biological data interpretation. Thus, multiple approaches are required to cover most of the metabolites. No software tool is capable of comprehensively translating all the data into a biologically meaningful context yet. In this review, we discuss the advantages of metabolome profiling and main obstacles limiting progress in systems biology.
How lateral interaction develops in a self-organizing feature map

A biologically motivated mechanism for self-organizing a neural network with modifiable lateral connections is presented. The weight modification rules are purely activity-dependent, unsupervised, and local. The lateral interaction weights are initially random, but develop into a 'Mexican hat' shape around each neuron. At the same time, the external input weights self-organize to form a topological map of the input space. The algorithm demonstrates how self-organization can bootstrap itself using input information. Predictions of the algorithm agree very well with experimental observations on the development of lateral connections in cortical feature maps. <<ETX>>
Stemming the Tide of Academic Dishonesty in Higher Education: It Takes a Village

Universities stand for truth and knowledge. Academic integrity is the ideal we hold up to our students and ourselves. It's based on respect for the work we do and respect for the work of others. The current state of academic dishonesty on campus is a threat to the morality of the students, the integrity of their grades, and the reputation of our institutions of higher education. This article explores issues surrounding academic integrity with an eye toward considering what can be done. It discusses the breadth and types of cheating (including plagiarism), the impact of technology, ways to prevent or limit its occurrence, and ways faculty might respond when it occurs. The discussion is enriched by the results of two surveys about academic integrity conducted in late 2012 and early 2013—one of faculty and one of students. Results reveal and compare the concerns and suggestions of both groups.
MICROPROPAGATION OF STRAWBERRY ( Fragaria ananassa ) THROUGH RUNNER CULTURE

In vitro propagation of strawberry was conducted at the Biotechnology Lab. of BARI, Joydebpur, Gazipur. For shoot induction, five BAP concentrations viz., 0.0 (Control), 0.5, 1.0, 1.5, and 2.0 mg/l and for root induction four IBA concentrations viz., 0.0 (Control), 0.5, 1.0, and 1.5 mg/l were used. The highest average number of shoots (7) and the highest average length (3.34 cm) of shoot was observed at the concentration of 0.5 mg/l BAP. The highest average number of leaves (5) was also observed at the same concentration. Among the five rooting concentrations, IBA @ 0.5 mg/l showed the best performance in all the parameters studied. The highest number (6) of roots/culture and the longest (3.05 cm) roots were also obtained from this concentration. Half strength MS media without IBA concentration did not show any response regarding root induction.
Potential effects of sudden oak death on small mammals and herpetofauna in coast live oak ( Quercus agrifolia woodlands

Within San Luis Obispo County, California, coast live oak (Quercus agrifolia) woodlands provide important habitat for many wildlife species (see Tietje and others, this volume). Unfortunately, many of these woodlands are at high risk of sudden oak death (SOD) infection should the pathogen (Phytophthora ramorum) become established in the County (Meentemeyer and others 2004). To assess the potential impacts of SOD on the small mammal and herpetofaunal communities in this high-risk habitat, we surveyed for these taxa at three separate high-risk study sites within the County. We considered the co-occurrence of California bay laurel (Umbellularia californica) to be an indicator of high-risk woodlands. We then developed a priori regression models relating the abundance of the most common species to habitat structure and compared competing models using adjusted Akaike’s Information Criterion (AICc) values (Burnham and Anderson 2002). Finally, we projected the potential effects of SOD on these species in San Luis Obispo County by comparing vegetation data that we collected at infected and uninfected sites in the San Francisco Bay Area.
Structural Features and Antiviral Activity of Sulphated Fucans from the Brown Seaweed Cystoseira Indica

Natural compounds offer interesting pharmacological perspectives for antiviral drug development. In this study, we have analysed sulphated-fucan-containing fractions isolated from the brown seaweed Cystoseira indica. The crude water extract (CiWE) and the main fraction (CiF3) obtained by anion exchange chromatography had potent antiviral activity against herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) without cytotoxicity for Vero cell cultures. Furthermore, they had no direct inactivating effect on virions in a virucidal assay, and lacked anticoagulant activity. The mode of action of these compounds could be mainly ascribed to an inhibitory effect on virus adsorption. Chemical, chromatographic and spectroscopic methods showed that the major polysaccharide had an apparent molecular mass of 35 kDa and contained a backbone of α-(1→3)-linked fucopyranosyl residues substituted at C-2 with fucopyranosyl and xylopyranosyl residues. This sulphated fucan, considered the active principle of the C. indica water extract, also contained variously linked xylose and galactose units and glucuronic acid residues. Sulphate groups, if present, are located mostly at C-4 of (1→3)-linked fucopyranosyl units, and appeared to be very important for the anti-herpetic activity of this polymer.
Leader-Member Exchange Quality and Effectiveness Ratings

Survey data were collected from 127 subordinate-supervisor dyads employed in diverse organizational settings. Hierarchical regression analyses revealed that subordinate-supervisor conscientiousness similarity predicted subordinate in-role behavior. Also, subordinate in-role behavior closely approached significance as a predictor of higher quality leader-member exchanges (LMX), whereas LMX was correlated with subordinate organizational citizenship behavior and supervisor effectiveness. As a function of conscientiousness similarity, the observed relationships are explained in terns of improved subordinate-supervisor compatibility and reciprocity. Examples are provided.
Color Music

A PSYCHOLOGICAL MONOGRAPH reporting experiments on color music has just been published, and it is likely to lead to much discussion in psychology and music,' especially in connection with the present excitement about color with music in moving pictures and color organs. This author found that "a preliminary survey of 274 college students revealed 165, or 60 per cent, who showed some tendency to associate color with short musical selections. "
Mutation heterogeneity of cystic fibrosis in France: Screening by denaturing gradient gel electrophoresis using psoralen‐modified oligonucleotide

In order to establish counseling guidelines and aid carrier risk assessment, we sought to establish the frequencies of cystic fibrosis (CF) mutations that are present in CF families living in the Ile de France region, a region notable for its ethnic heterogeneity. We studied 470 CF chromosomes in which we identified more than 90% of the CF mutations. We systematically screened 21 exons and the adjacent sequences of the CF transmembrane conductance regulator (CFTR) gene by denaturing gradient gel electrophoresis using chemical clamps. We detected 41 different CF mutations located in 14 exons. One of these mutations had not been previously described. Given the heterogeneity of these mutations, population screening does not appear to be readily feasible in our population. © 1995 Wiley‐Liss, Inc.
Loss of Tropomodulin4 in the zebrafish mutant träge causes cytoplasmic rod formation and muscle weakness reminiscent of nemaline myopathy

Nemaline myopathy is an inherited muscle disease that is mainly diagnosed by the presence of nemaline rods in muscle biopsies. Of the nine genes associated with the disease, five encode components of striated muscle sarcomeres. In a genetic zebrafish screen, the mutant träge (trg) was isolated based on its reduction in muscle birefringence, indicating muscle damage. Myofibres in trg appeared disorganised and showed inhomogeneous cytoplasmic eosin staining alongside malformed nuclei. Linkage analysis of trg combined with sequencing identified a nonsense mutation in tropomodulin4 (tmod4), a regulator of thin filament length and stability. Accordingly, although actin monomers polymerize to form thin filaments in the skeletal muscle of tmod4trg mutants, thin filaments often appeared to be dispersed throughout myofibres. Organised myofibrils with the typical striation rarely assemble, leading to severe muscle weakness, impaired locomotion and early death. Myofibrils of tmod4trg mutants often featured thin filaments of various lengths, widened Z-disks, undefined H-zones and electron-dense aggregations of various shapes and sizes. Importantly, Gomori trichrome staining and the lattice pattern of the detected cytoplasmic rods, together with the reactivity of rods with phalloidin and an antibody against actinin, is reminiscent of nemaline rods found in nemaline myopathy, suggesting that misregulation of thin filament length causes cytoplasmic rod formation in tmod4trg mutants. Although Tropomodulin4 has not been associated with myopathy, the results presented here implicateTMOD4 as a novel candidate for unresolved nemaline myopathies and suggest that the tmod4trg mutant will be a valuable tool to study human muscle disorders.
Rosa26 Locus Supports Tissue-Specific Promoter Driving Transgene Expression Specifically in Pig

Genetically modified pigs have become a popular model system in fundamental research, agricultural and biomedical applications. However, random integration often result in unstable expression of transgene and unpredictable phenotypes. The Rosa26 locus has been widely used to produce genetic modified animals with high and consistent expressing of transgene in mouse, human and rat, as it can be targeted efficiently and is not subject to gene-silencing effects. Recently, the first case of reporter gene targeting pigs in porcine Rosa26 (pRosa26) locus was reported. In the study, full sequence of pRosa26 locus was further characterized, and the pRosa26 promoter (pR26) was cloned and we evidenced that the new porcine endogenous promoter is suitable for driving transgene expression in a high and stable manner by avoiding DNA methylation. Furthermore, elongation factor 1a promoter (EF1a) -driven GFP reporter and Myostatin promoter (MyoP)-driven Follistatin (Fst) were successfully targeted into the pRosa26 locusby traditional homologous recombination (HR) strategy. EF1a showed high activity and hypomethylation at the locus. And, muscle-specific promoter MyoP was activated strictly in muscle of the pRosa26 targeted pigs, indicating Rosa26 locus supports tissue-specific promoter driving transgene expression in its own manner. The study provided further demonstration on biomedical and agricultural applications of porcine Rosa26 promoter and locus.