Miracle-dz/UniFAR-FTUs huggingface dataset:
Miniaturized W slot ultra wide band microstrip antenna for short distance communication

UWB is an emerging technology and has numerous applications in different fields in this digital era. As we know that the range of UWB exist are 3.1GHz–10.6 GHz but some narrow band applications also exist in this range and causes interference to Ultra Wideband applications. In this proposed work a novel UWB antenna is integrated with W shape notch to reduce interference which mainly occurs at 5 GHz due to WLAN (IEEE 802.11a) and it also cover U-NII band (5.15–5.85 GHz). The proposed antenna is designed using FR-4 substrate, size of proposed antenna is 25×20 mm2 which makes it very compact and thickness is 1.6mm and fed through micro strip line to achieve better impedance matching. The range of proposed antenna is 3.4 GHz to 11 GHz and return loss of 36 dB at resonant frequency is 4.4 GHz observed for the proposed antenna and achieve VSWR <2. The proposed antenna is well suited for the wireless USB.
Prevalence of menstrual migraine: A population-based study

Aim To present data from a population-based epidemiological study on menstrual migraine. Material and methods Altogether, 5000 women aged 30–34 years were screened for menstrual migraine. Women with self-reported menstrual migraine in at least half of their menstrual cycles were invited to an interview and examination. We expanded the International Classification of Headache Disorders III beta appendix criteria on menstrual migraine to include both migraine without aura and migraine with aura, as well as probable menstrual migraine with aura and migraine without aura. Results A total of 237 women were included in the study. The prevalence among all women was as follows: any type of menstrual migraine 7.6%; menstrual migraine without aura 6.1%; menstrual migraine with aura 0.6%; probable menstrual migraine without aura 0.6%; probable menstrual migraine with aura 0.3%. The corresponding figures among female migraineurs were: any type of menstrual migraine 22.0%, menstrual migraine without aura 17.6%, menstrual migraine with aura 1.7%, probable menstrual migraine without aura 1.6% and probable menstrual migraine with aura 1.0%. Conclusion More than one of every five female migraineurs aged 30–34 years have migraine in ≥50% of menstruations. The majority has menstrual migraine without aura and one of eight women had migraine with aura in relation to their menstruation. Our results indicate that the ICHD III beta appendix criteria of menstrual migraine are not exhaustive.
Timing-Driven Steiner Tree Construction with Wire Sizing, Buffer Insertion and Obstacle Avoidance

In this paper, given a set of connecting nodes in a signal net, based on the result of optimal wire width and buffer insertion in a wire segment (Yan, 2006) and the concept of sharing-buffer insertion and hidden Steiner-point assignment, an effective tree construction approach is proposed to construct a timing-driven rectilinear Steiner tree with wire sizing, buffer insertion and obstacle avoidance. The experimental results show that our proposed approach obtains better timing-driven Steiner trees than our previous approach (Dechu et al., 2004) for the tested signal nets.
Effects of alcohol on tests of executive functioning in men and women: a dose response examination.

Alcohol has been shown to affect performance on tasks associated with executive functioning. However, studies in this area have generally been limited to a single dose or gender or have used small sample sizes. The purpose of this study was to provide a more nuanced and systematic examination of alcohol's effects on commonly used tests of executive functioning at multiple dosages in both men and women. Research volunteers (91 women and 94 men) were randomly assigned to one of four drink conditions (alcohol doses associated with target blood alcohol concentrations of .000%, .050%, .075%, and .100%). Participants then completed three tasks comprising two domains of executive functioning: two set shifting tasks, the Trail Making Test and a computerized version of the Wisconsin Card Sorting Task, and a response inhibition task, the GoStop Impulsivity Paradigm. Impaired performance on set shifting tasks was found at the . 100% and . 075% dosages, but alcohol intoxication did not impair performance on the GoStop. No gender effects emerged. Thus, alcohol negatively affects set shifting at moderately high levels of intoxication in both men and women, likely attributable to alcohol's interference with prefrontal cortex function. Although it is well established that alcohol negatively affects response inhibition as measured by auditory stop-signal tasks, alcohol does not appear to exert a negative effect on response inhibition as measured by the GoStop, a visual stop-signal task.
Dissociation of airway responsiveness and bronchoalveolar lavage (BAL) cell composition in sensitized guinea–pigs after daily inhalation of ovalbumin

Summary. The association between inflammatory cell influx, cell activation status and change of airway responsiveness to acelylcholine (ACh) after daily inhalation of ovalbumin (OA) in sensitized guinea–pigs was investigated. Starting 3 weeks after sensitization (OA at 50mg/kg s.c. + i.p.) guinea–pigs were exposed daily to 2% OA (10min: undercover of 0.5Smg/kg mepyramine i.p. 15min before OA) for 2 weeks. Concentration–response curves (CRCs) for inhaled ACh were performed 24 h after the last OA–challenge and 24 h after another single OA–inhalation 1 week later. CRCs for inhaled ACh were neither affected 24 h after the last OA challenge (daily for two weeks) nor 24 h after another OA–inhalation one week later. In contrast, bronchoalveolar lavage (BAL) from repeatedly OA– sensitized/–challenged guinea–pigs immediately after the last CRC showed a significant increase of total cell count by about tenfold and increases in eosinophils by about 20–fold, neutrophils by 30–fold, macrophages by about fivefold and lymphocytes by about tenfold (P < 0.05. multiple Wilcoxon–test). In contrast, markers of cell activation (EPO, MPO) were significantly decreased (P < 0.05). Methylprednisolone almost completely prevented these changes in increased cell numbers and decreased cell activation (vs OA contr., P < 0.05). The lack of increased airway hyperresponsiveness despite a massive inflammatory cell influx suggests other factors controlling airway responsiveness than inflammation.
How Often Should a Port-A-Cath be Flushed?

While it is important during treatment to flush the port-A-cath (PAC) with heparin regularly, catheter maintenance needs to be evaluated in those patients who, after completion of therapy, retained their ports for extended periods of time. The manufacturer has recommended monthly accession to maintain catheter patency and function. Our objective is to demonstrate that a longer interval between maintenance accessions of PACs still may be medically safe, convenient, and more efficient. We performed a retrospective review of all patients who had undergone PAC insertion from 1988 to 1993 at the Albert Einstein College of Medicine, and from 1997 to 2002 at the New York Hospital Medical Center of Queens. An adequate maintenance time is defined as a period of at least 6 months without chemotherapy or total parenteral nutrition. Data collected included date and location of PAC insertion, date of PAC accessions, PAC complications, and results of attempts at flushing the catheters with no venous blood return. All data were entered into an Excel spreadsheet and analyzed. The difference in interval accessions in patients without any complication to patients with complication was calculated using the Mann-Whitney “U” test. A total of 73 patients were included in the study. Compliance with visits for PAC maintenance varied considerably with the individual median accession times varying between 28 and 262 days with an overall median of 42 days. The individual means ranged from 29.5 to 244 days with an overall mean of 53.6 days. Seven patients in the group had episodes where the provider was unable to draw blood from the port during routine accession. The average intervals between accessions for each of these patients ranged from 38 to 244 days. The average intervals of accession among those patients who had no blood return during PAC accession was 79 days, versus 63 days for those without any difficulty. The difference was not statistically significant (p > 0.05). Monthly maintenance of PAC is excessive, inconvenient for the patients, and expensive. Extending the interval of PAC maintenance proves to be medically safe and beneficial to the patients, the physicians and the health care system. Our clinical experience suggests that less frequent accessions of PACs is safe and feasible. We strongly advocate future prospective investigation of alternative PAC maintenance protocols in gynecologic cancer patients.
Review of arrangements for disagreement resolution (SEND)

The Children and Families Act 2014 and the related Special educational needs and disability code of practice: 0-25 years (SEND code of practice) (DfE, 2015) place a greater emphasis than before on the avoidance of disagreements through a person centred approach to decision-making and open communication between professionals and parents and young people (SEND code of practice, paragraph 11.1). Where disagreements and complaints arise, the legislation and the code make clear that parents and young people should be given information and, where they choose, support to enable participation in disagreement resolution and complaints processes. Local authorities (LAs) must therefore provide an information, advice and support service, an independent local disagreement resolution service and mediation service(s). The mediation service includes mediation advice (i.e. providing information about what mediation is and can offer) and full mediation. Local authorities must inform parents and young people about these services, as well as of complaints procedures, and procedures for appealing to the English First-tier Tribunal SEND. The reforms aim to reduce the incidence of disagreements and to achieve earlier resolution of those that do arise.
Local perspectives of Plecoglossusaltivelis determine searching strategy

We argue for the notion of adaptability in collective behavior, treating real fish schools as an example. For evaluation, we use the inconsistent relation between local and global perspectives. We show that this inconsistency would affect whole group behaviors and lead them to use different strategies.We argue for the notion of adaptability in collective behavior, treating real fish schools as an example. For evaluation, we use the inconsistent relation between local and global perspectives. We show that this inconsistency would affect whole group behaviors and lead them to use different strategies.
Antiviral and Regulatory T Cell Immunity in a Patient with Stromal Interaction Molecule 1 Deficiency

Stromal interaction molecule 1 (STIM1) deficiency is a rare genetic disorder of store-operated calcium entry, associated with a complex syndrome including immunodeficiency and immune dysregulation. The link from the molecular defect to these clinical manifestations is incompletely understood. We report two patients with a homozygous R429C point mutation in STIM1 completely abolishing store-operated calcium entry in T cells. Immunological analysis of one patient revealed that despite the expected defect of T cell proliferation and cytokine production in vitro, significant antiviral T cell populations were generated in vivo. These T cells proliferated in response to viral Ags and showed normal antiviral cytotoxicity. However, antiviral immunity was insufficient to prevent chronic CMV and EBV infections with a possible contribution of impaired NK cell function and a lack of NKT cells. Furthermore, autoimmune cytopenia, eczema, and intermittent diarrhea suggested impaired immune regulation. FOXP3-positive regulatory T (Treg) cells were present but showed an abnormal phenotype. The suppressive function of STIM1-deficient Treg cells in vitro, however, was normal. Given these partial defects in cytotoxic and Treg cell function, impairment of other immune cell populations probably contributes more to the pathogenesis of immunodeficiency and autoimmunity in STIM1 deficiency than previously appreciated.
LTCC Layer-to-Layer Misalignment-Tolerant Coupled Inductors and Their Application to Bandpass Filter and Helical Inductors

Mutual inductance between coupled inductors can provide large equivalent series inductance required by filter design. As mutual inductance is dependent on the distance between coupled metal lines within coupled inductors, mutual inductance in traditional straight line coupled inductors (SLCI) is susceptible to layer-to-layer misalignment during fabrication if two coupled lines are located at different substrate layers. Misalignment-tolerant coupled inductors (MaTCI) are proposed to alleviate the effect of misalignment on mutual inductance. Circuit model is also proposed to describe their mechanism. Their performance is verified and compared with traditional SLCI using coupled inductors based transmission zero circuits and bandpass filters. Measurement results of three samples of a transmission zero circuit based on proposed MaTCI show only 0.56% frequency variation at 1.9 GHz, while traditional SLCI give about 3.2% variation from samples at the same low temperature cofired ceramic substrate. Measured results of three samples of a bandpass filter using MaTCI also show more stable performance at transmission zero frequency, insertion loss and passband bandwidth as compared with the filter using traditional SLCI. Electromagnetic simulation also shows similar performance improvement for MaTCI under misalignment. The same concept is also applied to helical inductor and two misalignment tolerant helical inductors are proposed. Simulation results show that they are more stable than the traditional stacked helical inductor.
Asymptotic Analysis of Semi-Parametric Weighted Null-Space Fitting Identification

Standard system identification methods often provide biased estimates with closed-loop data. With the prediction error method (PEM), the bias issue is solved by using a noise model that is flexible enough to capture the noise spectrum. However, a too flexible noise model (i.e., too many parameters) can cause additional numerical problems for PEM. In this paper, we perform a theoretical analysis of the weighted null-space fitting (WNSF) method when a parametric noise model is not estimated. With this method, the system is first captured using a non-parametric ARX model, which is then reduced to a parametric model of interest. In the reduction step, a noise model does not need to be estimated if it is not of interest. In open loop, this still provides asymptotically efficient estimates of the dynamic model. In closed loop, the estimates are consistent, and their covariance is optimal for a non-parametric noise model. In this paper, we prove these results, which require additional technical details compared with the case with a full parametric model structure. In particular, we use a geometric approach for variance analysis, deriving a new result that will be instrumental to our end. Finally, we use a simulation study to illustrate the benefits of the method when the noise model cannot be parametrized by a low-order model.
Towards a communication perspective on entrepreneurship

Our research topics deal with communication and persuasion issues related to entrepreneurship. We thus decided to organize our research presentation in two main chapters, the first dedicated to potential and confirmed entrepreneurs as targets of persuasive attempts generated by media (press discourse) and interpersonal (entrepreneurial support and education) sources, the second dedicated to potential and confirmed entrepreneurs as sources of persuasive interpersonal communications directed towards various stakeholders such as business angels, clients, or employees in the context of pitch presentations, business model elaboration and team leadership. A third chapter is dedicated to current and future research projects.
Vascular adventitia generates neuronal progenitors in the monkey hippocampus after ischemia

In the adult hippocampus, neurogenesis proceeds in the subgranular zone (SGZ) of the dentate gyrus (DG), but not in the cornu Ammonis (CA). Recently, we demonstrated in monkeys that transient brain ischemia induces an increase of the neuronal progenitor cells in the SGZ, but not in CA1, in the second week after the insult. To identify the origin of primary neuronal progenitors in vivo, we compared the postischemic monkey DG and CA1, using light and electron microscopy, focusing on specific phenotype markers, as well as the expression of neurotrophic factors. Laser confocal microscopy showed that 1–3% of 5‐bromo‐2′‐deoxyuridine (BrdU)‐positive cells in the SGZ after 2–96 h labeling were also positive for neuronal markers such as TUC4, βIII tubulin, and NeuN on days 9 and 15. In contrast, despite the presence of numerous BrdU‐positive cells, CA1 showed no neurogenesis at any time points, and all the progenitors were positive for glial markers: Iba1 or S‐100β on days 4, 9, and 15. Highly polysialylated neural cell adhesion molecule (PSA‐NCAM)‐positive cells were abundant in the SGZ, but were absent in CA1. On day 9, most of the immature neurons positive for βIII‐tubulin in SGZ showed an increase in PSA‐NCAM immunoreactivity. The immunoreactivity of brain‐derived neurotrophic factor (BDNF) was abundant at the vascular adventitia of the SGZ, but was absent at the adventitia of CA1. BrdU‐positive progenitor cells were frequently seen in the vicinity of proliferating blood vessels. Ultrastructural analysis indicated that most of the neuronal progenitor cells and microglia originated from the pericytes of capillaries and/or adventitial cells of arterioles (called vascular adventitia). The detaching adventitial cells showed mitotic figures in the perivascular space, and the resultant neuronal progenitor cells made contact with dendritic spines associated with synaptic vesicles or boutons. These data implicate the vascular adventitia as a novel potential source of neuronal progenitor cells in the postischemic primate SGZ. © 2004 Wiley‐Liss, Inc.
A minimal factor overlap method for resolving ambiguity in factor analysis of dynamic cardiac PET

Factor analysis has been pursued as a means to decompose dynamic cardiac PET images into different tissue types based on their unique physiology. Each tissue is represented by a time-activity profile (factor) and an associated spatial distribution (structure). Decomposition is based on non-negative constraints of both the factors and structures; however, additional constraints are required to achieve a unique solution. In this work we present a novel method (minimal factor overlap - MFO) and compare its performance to a previously published constraint (minimal spatial overlap - MSO). We compared both methods using simulated data and on a canine model with variable 82Rb infusion profiles. Biasing of factors due to spillover is reduced with MFO compared to MSO, while the robustness and reproducibility of MSO is maintained.
The COP9 Signalosome Interacts with and Regulates Interferon Regulatory Factor 5 Protein Stability

ABSTRACT The transcription factor interferon regulatory factor 5 (IRF5) exerts crucial functions in the regulation of host immunity against extracellular pathogens, DNA damage-induced apoptosis, death receptor signaling, and macrophage polarization. Tight regulation of IRF5 is thus warranted for an efficient response toward extracellular stressors and for limiting autoimmune and inflammatory responses. Here we report that the COP9 signalosome (CSN), a general modulator of diverse cellular and developmental processes, associates constitutively with IRF5 and promotes its protein stability. The constitutive CSN/IRF5 interaction was identified using proteomics and confirmed by endogenous immunoprecipitations. The CSN/IRF5 interaction occurred on the carboxyl and amino termini of IRF5; a single internal deletion from amino acids 455 to 466 (Δ455-466) was found to significantly reduce IRF5 protein stability. CSN subunit 3 (CSN3) was identified as a direct interacting partner of IRF5, and knockdown of this subunit with small interfering RNAs resulted in enhanced degradation. Degradation was further augmented by knockdown of CSN1 and CSN3 together. The ubiquitin E1 inhibitor UBEI-41 or the proteasome inhibitor MG132 prevented IRF5 degradation, supporting the idea that its stability is regulated by the ubiquitin-proteasome system. Importantly, activation of IRF5 by the death receptor ligand tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) resulted in enhanced degradation via loss of the CSN/IRF5 interaction. This study defines CSN to be a new interacting partner of IRF5 that controls its stability.
An indirect adaptive fuzzy speed controller for permanent magnet synchronous motor

This paper describes the application of indirect adaptive fuzzy control to the speed controller of permanent magnet synchronous motor (PMSM) under external load disturbances and parameter variations in the plant. The proposed indirect adaptive fuzzy speed controller is based on feedback linearization and its parameters are updated by both speed tracking error and filtered prediction error, designed by Lyapunov synthesis. Moreover, the singleton fuzzy system is designed to approximate the unknown plant of PMSM in the proposed controller. This paper is structured as follows. First, the model of the PMSM is introduced. Then, a speed control scheme is proposed. Furthermore, the design procedure of the indirect adaptive fuzzy control algorithm is described. Finally, the effectiveness of the proposed controller is verified by simulations compared with the integral-proportional (IP) speed controller. The proposed controller is found not only to be robust to changes in load and system parameters, but also to have high tracking performance. Suggestion is also provided for the practical implementation.
THE INVESTIGATION OF FUNDAMENTAL EFFECTS, INTEREST RATE, EXCHANGE RATE AND INFLATION ON STOCK RETURN OF BANKING SECTOR IN INDONESIA STOCK EXCHANGE

The objective of the study is to examine the effect of financial fundamentals proxied by the CAMEL ratio and to examine macroeconomic variables on stock returns. CAMEL ratio measurements use several aspects such as, capital, assets, management, earnings and liquidity. The five aspects are measured by using several indicators: CAR, NPL, ROE, NIM, BOPO and LDR. In the other hand, the macroeconomic variables consist of interest rate, exchange rate and inflation. Samples used in this study were obtained by applying the purposive sampling method. The research sample consists of sixteen companies that engage in the banking sector during period 2002 to 2011. The hypothesis testing conducted by using panel data regression, (10-year time series and 16 cross section). Furthermore, this analysis technique requires an appropriate model in order to obtain an efficient estimation results and also BLUE criteria (Best, Linear, Unbiased, and Estimator). Based on the results of testing with chow test, it was determined that the model estimate used in this study is common effect model or also called as PLS (Pooled Least Square). The estimation results by using common effect model reveals that some of financial ratios show a bit contrary to the theory, in which the ratio of CAR shows positive sign but does not have a significant effect on stock returns. Furthermore, the ratio of NPL does not affect the return. ROE and LDR show positive and significant effect on return, meanwhile NIM and BOPO show negative sign and significant impact on return. The further macroeconomic variables, interest rate, exchange rate and inflation consistent with the theory, which are negative and significantly effect on stock return companies belonging to the banking sector.