Miracle-dz/UniFAR-FTUs huggingface dataset:
Issues Regarding the Clinical Use of the Classification of Violence Risk (COVR) Assessment Instrument

The MacArthur Study of Mental Disorder and Violence produced an instrument for classifying hospitalized psychiatric patients according to their risk of behaving violently following discharge. The instrument, Classification of Violence Risk (COVR) has been computerized and is now commercially available to clinicians. A validation study performed by the original researchers showed that when the instrument was applied to a new sample of patients, it demonstrated a considerable reduction in positive predictive power. Potential factors affecting the instrument's accuracy in applied settings are reviewed. It is concluded that, until additional research clarifies uncertainty about the instrument, clinicians would do well to be very cautious in utilizing COVR results to make judgments as to violence risk, particularly when the test results suggest a high risk of future violence.
The what, who and how of innovation generation

The majority of companies agree that innovation is one of their top priorities. However, there is much disagreement about what innovation exactly entails, who carries the responsibility for innovation, and how the process of creating innovation is structured. The “what” of innovation has shifted from a focus on process and product innovation to a focus on service and business model innovation. Companies such as Tesla, Nespresso and Netflix have revolutionized industries with their disruptive business models. The “who” issue for many companies has shifted from a pure top-down model to a more open and bottom-up approach. Incumbents such as P&G and IBM have embraced new sources of innovation and have welcomed customers to their ideation process. Others, such as Michelin and Merck, have leveraged the immense potential of their employee base through grassroots innovation. Finally, the “how” of innovation concerns the various processes of creating innovation, which range from structured stage-gates to leaner ones. Startups such as LinkedIn and Dropbox have fully embraced the lean mentality, decreasing the time to develop the product by involving customers in the early development stages. In this chapter, we provide researchers and managers with a comprehensive review of the innovation generation process. We shed light on the different facets of the process by discussing case examples from a wide variety of industries and by drawing insights from both startups and multinationals. This chapter helps managers better understand what it takes to innovate and provides an overview of the tools at their disposal. This chapter is organized as follows. In Section 3.2, we discuss four types of innovation (what) and how companies can combine them to achieve success. We complement this discussion with a classification of innovation based on the differences in risk and time horizon. We thus set the stage by reviewing avenues companies can pursue in their innovation agenda. This is followed by a discussion of who then takes responsibility for innovation. Hence, in Section 3.3, we review five methodologies for innovation (who) and the transition from a closed to a more open model of innovation generation. In Section 3.4, we explore five innovation processes (how) and disentangle their advantages and disadvantages. Figure 3.1 provides an overview of the components of the innovation generation process that this chapter explores.
The impact of a restructuring process on employee morale at a private security company

ii ABSTRACT This study was conducted because a private security company underwent a restructuring process due to a change in Managing Director in 2016. The company represented is one of the largest private security companies in the Vanderbijlpark area and enjoys a client base of just over 3000 clients in the area. After undergoing a change in Managing Director, it changed its strategic objectives and embarked on a restructuring process in order to leverage talent as well as acquire new talent in line with the new objectives. The objective of this study was to investigate the effect of a restructuring process on the effect on the employee morale of the employees of the organisation. Upon examination, it was found that there is a strong correlation between communication from top management and maintaining positive employee morale during a restructuring process. Furthermore, it was found that employees were more likely to display positive morale during a restructuring process if they were job secure. The implications of this study for improving employee morale are investigated and discussed.
A sub-ns time-gated CMOS single photon avalanche diode detector for Raman spectroscopy

A time-gated single photon avalanche diode (SPAD) has been designed and fabricated in a standard high voltage 0.35 μm CMOS technology for Raman spectroscopy. The sub-ns time gating window is used to suppress the fluorescence background typical of Raman studies, and also to minimize the dark count rate in order to maximize the signal-to-noise ratio of the Raman signal. The proposed time-gating technique is applied for measuring the Raman spectra of olive oil with a gate window of 300 ps, and shows significant fluorescence suppression.
MHC Class II Molecules Control Murine B Cell Responsiveness to Lipopolysaccharide Stimulation1

LPS is a strong stimulator of the innate immune system and inducer of B lymphocyte activation. Two TLRs, TLR4 and RP105 (CD180), have been identified as mediators of LPS signaling in murine B cells, but little is known about genetic factors that are able to control LPS-induced cell activation. We performed a mouse genome-wide screen that aside from identifying a controlling locus mapping in the TLR4 region (logarithm of odds score, 2.77), also revealed that a locus closely linked to the MHC region (logarithm of odds score, 3.4) governed B cell responsiveness to LPS stimulation. Using purified B cells obtained from MHC congenic strains, we demonstrated that the MHCb haplotype is accountable for higher cell activation, cell proliferation, and IgM secretion, after LPS stimulation, when compared with the MHCd haplotype. Furthermore, B cells from MHC class II−/− mice displayed enhanced activation and proliferation in response to LPS. In addition, we showed that the MHC haplotype partially controls expression of RP105 (a LPS receptor molecule), following a pattern that resembles the LPS responsiveness phenotype. Together, our results strongly suggest that murine MHC class II molecules play a role in constraining the B cell response to LPS and that genetic variation at the MHC locus is an important component in controlling B cell responsiveness to LPS stimulation. This work raises the possibility that constraining of B cell responsiveness by MHC class II molecules may represent a functional interaction between adaptive and innate immune systems.
Quantitative gait analysis in unconstrained total knee arthroplasty patients

Clinical results as well as survivorship of knee joint endoprostheses have improved enormously during the last two decades. Key terms such as ‘minimal bone resection’, ‘reduced interface stress’ and ‘unconstrained bicondylar knees’ have been trendsetting for the change from hinged to bicondylar knee prostheses. Due to a tendency of reduced incidence of aseptic loosenings and infections, patellar complications represent the most frequent reason for revision operations (Ayers et al., 1997; SchroederBoersch, 1998). Quality of life has been markedly improved (Rissanen et al., 1995), although there are still some unsolved problems left. These complaints of unknown origin are often connected with the patella and are simply described as ‘anterior knee pain’ (Boyd et al. (1993). Evaluation of functional parameters that cannot be registered by clinical or radiological examinations has gained importance. These functional investigations comprise proprioceptive tests, isokinetic strength assessment as well as analysis of gait pattern. In this study, gait analysis as well as clinical and qualityof-life assessment were carried out on total knee arthroplasty patients, in order to identify possible causes of residual complaints after total knee arthroplasty. In contrast to previous studies, which were mainly aimed at improving gait velocity preand postoperatively, this study is the first to compare gait pattern at constant velocity with a healthy control group of the same age.
Grid-Connected Photovoltaic Generation Plants: Components and Operation

The main design objective of photovoltaic (PV) systems has been, for a long time, to extract the maximum power from the PV array and inject it into the ac grid. Therefore, the maximum power point tracking (MPPT) of a uniformly irradiated PV array and the maximization of the conversion efficiency have been the main design issues. However, when the PV plant is connected to the grid, special attention has to be paid to the reliability of the system, the power quality, and the implementation of protection and grid synchronization functions. Modern power plants are required to maximize their energy production, requiring suitable control strategies to solve the problems related to the partial shading phenomena and different orientation of the PV modules toward the sun. Moreover, the new policy concerning the injection of reactive power into the grid makes the development of suitable topologies and control algorithms mandatory. A general view of actual solutions for applications of the PV energy systems is presented. This article covers several important issues, including the most reliable models used for simulation, which are useful in the design of control systems, and the MPPT function, particularly in distributed applications. The main topologies used in the PV power processing system and, finally, grid connection aspects are discussed, with emphasis on synchronization, protections, and integration.
3D location of circular and spherical features by monocular model-based vision

Mathematics is presented for using monocular model-based vision to find 3D positions of circular and spherical model features, and, for the circular case, orientations as well. Monocular model-based vision here refers to the use of a single projective image of modeled objects to solve for the 3D positions and orientations of the objects in the scene. A novel closed-formed solution for the 3D position and orientation of a circular features and the 3D position of a spherical feature is described. There are two general solutions for the circular feature bu there is only one solution when the surface normal of the circular feature passes through the center of projection. There is only one solution for the circular case. Advantages of this method are: (1) it handles spherical as well as circular features; (2) it has a closed-form solution; (3) it gives only the necessary number of solutions (no redundant solutions); (4) it uses simple mathematics involving 3D analytic geometry; and (5) it is geometrically intuitive. <<ETX>>
A perception-based color recommendation algorithm for hierarchical regions

The visualization of hierarchical and nested spatial regions remains a challenge to cartographers. Despite progress in computer algorithms for visualizing general hierarchical data, mapping spatial hierarchical regions, especially with static, noninteractive means, still requires considerable manual efforts. This paper proposes a two-step algorithm that can automatically recommend perception-based colors and help reveal the hierarchical structure embedded in nested regions. It first systematically sorts regions according to their contiguity and containment relations at multiple hierarchical levels. Then, perception-based colors are generated using the order of regions with the goal of maximizing differentiability between top-level regions while retaining the perceived uniformity of the bottom-level regions. With the coloring scheme recommended by this algorithm, the metric color differences among regions mathematically reflect their hierarchical positions and spatial relations. The resultant colors, therefore, can potentially help map-readers perceive the spatially constrained hierarchy structure built in nested regions.
Cadophora malorum Cs‐8‐1 as a new fungal strain producing gibberellins isolated from Calystegia soldanella

Fourteen endophytic fungi with different colony morphologies were isolated from the roots of Calystegia soldanella. Endophytic fungi isolated from C. soldanella were identified by internal transcribed spacer (ITS) region. To verify plant growth promotion (PGP), culture filtrates of isolated endophytic fungi were treated in Waito‐c rice (WR) and C. soldanella seedlings. Culture filtrates of Cs‐8‐1 fungal strain had advanced PGP activity. The presence of physiologically bioactive gibberellins (GA) GA1 (1.213 ng ml−1), GA3 (1.292 ng ml−1), GA4 (3.6 ng ml−1), GA7 (1.328 ng ml−1), other inactive GA9 (0.796 ng ml−1) and GA12 (0.417 ng ml−1), GA20 (0.302 ng ml−1), GA24 (1.351 ng ml−1), GA34 (0.076 ng ml−1), and GA53 (0.051 ng ml−1) in culture filtrates of Cs‐8‐1 fungal strain was detected. The Cs‐8‐1 fungal strain was confirmed as a producer of GAs. Molecular analysis of sequences showed high similarity of 99% to Cadophora malorum. Consequentially, the Cs‐8‐1 fungal strain was identified as a new C. malorum producing GAs.
Knowledge-Based Bioeconomy: The Use of Intellectual Capital in Food Industry of Serbia

The main objective of this exploratory study was to identify and analyse the indicators of intellectual capital in food industry of Serbia. The study investigated managers’ perceptions of their usefulness, practical application, and factors that influence them. The respondents were surveyed by means of a questionnaire. They were mainly top managers from 18 food organizations, committed to the bioeconomy paradigm. The survey items were divided into three subcategories, namely human, structural, and relational capital. The data were analysed by the SPSS 21 statistical software. The results show that all indicators were perceived as very important, relational capital indicators being the most useful of all. Of all individual items, employee motivation, market share, and employee satisfaction were perceived as the most important. This study provides a perspective on managing intellectual capital in bioeconomy.
A Note on Market Structure with Transaction Costs

Transaction costs play a significant role in financial markets, and many studies have been conducted on this topic to date. Research on this topic may be divided into two categories. The first category of studies examines the optimal trading strategy of the investor who has to pay transaction costs. The second group investigates the optimal transaction costs that ensure the market operates as smoothly as possible, while retaining the profits of the market maker. We consider simultaneous optimization by the investors and the market maker, and analyse the impact of market parameters on the optimized transaction costs.
On and Offline Tangible Interaction: Studying the Secret Lives of Augmented Objects

The smart, augmented objects that appear in systems that support tangible interaction have a dual life. While they can exhibit complex digital behaviors in the technological context they are designed for, they are also static, standard physical objects in other situations: while stacked on the side of a table, placed in a pocket or held in a user's hand. This paper argues that to design truly effective tangible systems, we need consider both these situations - both the online and the offline. To illustrate this point, it briefly describes two studies into the offline use of tangible objects, highlighting lessons learnt for the design of future systems.
Liquidity constraints, risk preferences and farmers’ willingness to participate in crop insurance programs in Ghana

This paper analyzes smallholder farmers’ decisions to participate in crop insurance programs, using cross-sectional data from cocoa farmers in the Ashanti, Brong-Ahafo and Western Regions of Ghana. Given the significance of output uncertainty and imperfect capital and insurance markets, we develop a theoretical framework to show how risk preferences and liquidity constraints influence farmers’ crop insurance participation decisions. We use a stated preference approach to obtain information on farmers’ willingness to participate in crop insurance programs, and a discrete choice model to examine the factors that influence their participation decisions. We find that risk preferences and liquidity constraints influence farmers’ willingness to participate in crop insurance programs. The results also show that the probability of participating in crop insurance programs is higher for males, the more educated, and those who trust others. The levels of fertilizer and pesticide expenditure and the access to credit are also found to significantly influence the decision to adopt the programs.
Co-evolution of Capabilities’ and Alliance Portfolios: Multinational Firms in Global ICT Industry. Hargmaiste ettevõtete võimekuste ja liitude arendamine globaalses infotehnoloogiatööstuses

50 KOKKUVÕTE . 52 Article I . 55 Article II . 79 Article III . 87 Article IV . 115 CURRICILUM VITAE . 123 ELULOOKIRJELDUS . 125
Implementation and Evaluation of a Team Simulation Training Program

Background:Care of the trauma patient requires a well-coordinated intensive effort during the golden hour to optimize survival. Purpose:We hypothesized that this program would improve knowledge, satisfaction, self-confidence, and simulated team performance. Methods:A pre-, post-test design with N = 7 BSN nurses, 21 years of age, less than 2 years of intensive care unit and nursing experience. Setting:Trauma intensive care unit, single-center academic Level 1 trauma center. Results:Improvement was shown in perception of team structure (paired t test 13.71–12.57; p = .0001) and communication (paired t test 14.85–12.14; p = .009). Improvement was shown in observed situation monitoring (paired t test 17.42–25.28; p = .000), mutual support (paired t test 12.57–18.57; p = .000), and communication (paired t test 15.42–25.00; p = .001). A decrease was shown in attitudes of mutual support (paired t test 25.85–19.71; p = .04) and communication (paired t test 26.14–23.00; p = .001). Mean satisfaction scores were 21.5 of a possible 25 points. Mean self-confidence scores were 38.83 out of a possible 40 points. Discussion:Simulation-based team training improved teamwork attitudes, perceptions, and performance. Team communication demonstrated significant improvement in 2 of the 3 instruments. Most participants agreed or strongly agreed that they were satisfied with simulation and had gained self-confidence.
Type I IFN Induction in Response to Listeria monocytogenes in Human Macrophages: Evidence for a Differential Activation of IFN Regulatory Factor 3 (IRF3)1

Listeria monocytogenes is a prototypic bacterium for studying innate and adaptive cellular immunity as well as host defense. Using human monocyte-derived macrophages, we report that an infection with a wild-type strain, but not a listeriolysin O-deficient strain, of the Gram-positive bacterium L. monocytogenes induces expression of IFN-β and a bioactive type I IFN response. Investigating the activation of signaling pathways in human macrophages after infection revealed that a wild-type strain and a hemolysin-deficient strain of L. monocytogenes activated the NF-κB pathway and induced a comparable TNF response. p38 MAPK and activating transcription factor 2 were phosphorylated following infection with either strain, and IFN-β gene expression induced by wild-type L. monocytogenes was reduced when p38 was inhibited. However, neither IFN regulatory factor (IRF) 3 translocation to the nucleus nor posttranslational modifications and dimerizations were observed after L. monocytogenes infection. In contrast, vesicular stomatitis virus and LPS triggered IRF3 activation and signaling. When IRF3 was knocked down using small interfering RNA, a L. monocytogenes-induced IFN-β response remained unaffected whereas a vesicular stomatitis virus-triggered response was reduced. Evidence against the possibility that IRF7 acts in place of IRF3 is provided. Thus, we show that wild-type L. monocytogenes induced an IFN-β response in human macrophages and propose that this response involves p38 MAPK and activating transcription factor 2. Using various stimuli, we show that IRF3 is differentially activated during type I IFN responses in human macrophages.
A comparison of the effects of traditional production factors and sources of innovation on KIBS' performance: an empirical study of Taiwanese IC design firms

Knowledge-Intensive Business Services (KIBS) are important carriers, sources and facilitators of innovation. This study aims to analyse the factors that contribute to firms' performance in a KIBS subsector in Taiwanese Integrated Circuit (IC) design industry by proposing an integrative evolutionary production function, which includes traditional production factors such as physical capital and labour, as well as sources of innovation like internal Research and Development (R&D) and external technology acquisition. Based upon data from 68 Taiwanese IC design firms during 1993? 2005, this study was primarily concerned with modelling the factors that influence firm performance. Empirical results show that internal R&D is the most important factor that contributes to firm performance, followed by labour, external technology acquisition and physical capital. But the last two latter factors do not significantly influence firm performance. This study concludes that internal R&D and labour have the greatest explanatory power to enhance firm performance, especially in KIBS. If IC design firms want to raise their performance level, they have to invest more on internal R&D and labour than on physical capital and external technology acquisition.
Online parameter identification and generic modeling derivation of a dynamic load model in distribution grids

The advent of smart grids and the installation of phasor measurement units in the distribution network have renewed the interest on the measurement-based load modeling approach. In this paper, a real-time load modeling and identification procedure of the well-known exponential recovery dynamic load model using synchrophasor data is presented. The performance of the proposed method is evaluated using measurements recorded in a low-voltage laboratory scale test rig. Several parameters of the procedure are investigated to evaluate the applicability of the method under real world conditions, including the impact of filtering techniques, outlier rejection, model optimization algorithms, etc. The findings of this paper verify the validity of the proposed method for realtime applications.
Blurring image quality assessment method based on histogram of gradient

In this paper we propose a blurring image quality assessment (IQA) based on histogram of oriented gradients (HOG). The image quality can be determined by the slope value of the HOG of the target image. The representative line of HOG is approximated by a random sample consensus set (RANSAC). Simulation results performed on the LIVE image quality assessment database show that the proposed method aligns better with how the human visual system perceives image quality than several state-of-the-art IQAs.
Down‐regulation of S100A2 in lymph node metastases of head and neck cancer

Our cDNA microarray analysis of squamous cell carcinoma of the head and neck (SCCHN) previously identified that S100A2 was down‐regulated in highly metastatic 686LN‐M3s cell lines established through in vivo selection using a metastatic xenograft mouse model. S100A2, a putative tumor suppressor, has been found to be down‐regulated in several types of primary tumor as compared with the normal tissue. Only a few reports have explored its expression status and function in metastasis.