Miracle-dz/UniFAR-FTUs huggingface dataset:
VR-based construction tele-robot system displayed by HMD with active viewpoint movement mode

In this paper, a virtual reality-based construction tele-robot control system is investigated. The system consists of a servo-controlled construction robot, two joysticks for controlling the construction robot, and virtual workspace environment displayed by HMD. The position and shape of the task objects in virtual workspace environment are updated in real-time on basis of image information obtained by a stereo camera fixed in the remote field. The method of passive automatic viewpoint (PAV) has been proved to be superior in operability, safety, and reduction of stress than the conventional three-screen visual display method. However, PAV will not change when the construction robot doesn't move. In this case, it is difficult to finish the work task for the operator. To overcome the shortcomings, active viewpoint movement by a HMD named 3Dvisor device is introduced into this system, and two different viewpoint trajectories with straight-line and curved trajectories are used to move viewpoint. At last, the evaluation experiment results based on risk measurement using PAV and active viewpoint movement methods are both included. These experiments indicate that active changing of viewpoint by 3Dvisor device is effective to enhance safety in operation.
The Evolution of Non-Maternal Care in Anthropoid Primates: A Test of the Hypotheses

The amount of non-maternal care (allocare) found in primates varies greatly from species to species. Our paper examines this variation and focuses on possible reasons why mothers in some anthropoid primate species are prepared to relinquish their infants to other carers whereas others are not. We use data collected from the literature to test a number of hypotheses that attempt to explain the observed variation in non-maternal care. Analyses were carried out using comparative methods that control for the influence of both body size and phylogeny on life-history and ecological variation. The results support previous studies of both primates and other mammals in finding a clear link between the amount of allocare provided and female reproductive rates. Species with high allocare levels grow rapidly post-natally and wean their infants at a younger age (but at the same relative size) than species of the same body size with lower allocare levels. This early weaning allows high allocare species to support higher birth rates than low allocare species but does not result in earlier maturation. Our results, therefore, suggest that mothers allow non-maternal care of their infants in order to increase their own reproductive output. It is not clear whether such a strategy also benefits the infant, as we could find no link between the presence of allocare and early maturation (which would increase the infant’s reproductive output) or between allocare levels and infant survival (as measured by vulnerability to infanticide). This suggests that mothers and infants might come into conflict over transfer to other carers, as the benefits to the mother may not be accompanied by benefits to the infant. However, although mothers may benefit from allocare in some circumstances, they will not be expected to allow allocare if the costs are high (e.g. if there is a high risk to the infant).
Instrumentation optique pour la mesure des périkymaties de la couronne dentaire

L'etude du developpement physiologique humain et de sa variabilite a toujours ete au centre des preoccupations non seulement des anthropo-biologistes, mais egalement des medecins legistes, des dentistes, orthodontistes et des pediatres. Les attentes de la societe dans ce domaine de l'identification biometrique ont evolue. Desormais, la qualite des identifications ne se presume plus. Elle doit etre definie, evaluee, prouvee et, au-dela, constamment amelioree. L'objectif de cette these etait de concevoir et de realiser un systeme optique pour la mesure et l'analyse des perikymaties de la couronne de la dent. L'interet principal est de proposer un systeme non invasif pour la mise en evidence des perikymaties, utiliser, tester et evaluer la qualite d'une methode de comptage des perikymaties. Le but etant la determination de la periodicite des perikymaties, pour un classement des Hominides. En s'appuyant sur les theories optiques: la reflectance bidirectionnelle (BRDF) et la fonction bidirectionnelle de la texture (BTF), nous avons recu et realise un systeme optique qui repond a tous ces criteres. Au vu des resultats que nous avons obtenus sur des dents du registre des fossiles, largement etudies dans la litterature, nous pouvons souligner la pertinence de notre approche. En effet, les resultats de nos mesures ont demontre pour la premiere fois la variabilite chez l'Homme actuel. Le systeme optique que nous avons developpe permet aussi de mesurer la variabilite de la periodicite des perikymaties, rappelons que cette periodicite n'est que, tres partiellement connue chez l'Homme actuel et pourrait chevaucher celle observee chez les Hominides fossiles. Notre outil offre alors un outil objectif pour un classement des Hominides.
Wideband Signal DOA Estimation Based on Modified Quantum Genetic Algorithm

A new wideband signal DOA estimation algorithm based on modified quantum genetic algorithm (MQGA) is proposed in the presence of the errors and the mutual coupling between array elements. In the algorithm, the narrowband signal subspace fitting method is generalized to wideband signal DOA finding according to the character of space spectrum of wideband signal, and so the rule function is constructed. Then, the solutions is encoded onto chromosomes as a string of binary sequence, the variable quantum rotation angle is defined according to the distribution of optimization solutions. Finally, we use the MQGA algorithm to solve the nonlinear global azimuths optimization problem, and get optimization azimuths by fitness values. The computer simulation results illustrated that the new algorithm have good estimation performance.
El espacio geográfico de Guadix: aprovechamientos agrarios, propiedad y explotación

Este trabajo de investigacion tiene como objetivo fundamental analizar los cambios que se han producido en el paisaje agrario de guadix desde el s. Xviii al xx, asi como poner de manifiesto algunos problemas que afectan al lector agrario en el momento actual. En los diferentes capitulos de que consta la obra se han estudiado los siguientes aspectos: - modificaciones producidas en el termino municipal. - evolucion de la poblacion. Estructura por sexo y edad. Poblacion activa e inactiva y por situacion socioprofesional. - distribucion espacial de la poblacion y el habitat. - morfologia parcelaria. - cambios producidos en los cultivos y en los sistemas de cultivo. - los sistemas de explotacion y tenencia de la tierra. Analisis de los contratos de arrendamiento en base a los protocolos notariales. - caracteristicas de la propiedad agraria (1752-1860-1930 y 1988). Evolucion dinamica de la gran propiedad agraria, en base a los datos obtenidos del registro de la propiedad. - repercusiones de la p.A. C. En la agricultura accitana. - resultados y conclusiones
Benzylammonium heptanoate–heptanoic acid (1/1)

The title salt, C7H10N+·C7H13O2 −·C7H14O2, is an unusual 2:1 stoichiometric combination of two carboxylic acid molecules and one amine. Although there are crystal structures of a number of 1:1 complexes reported in the literature, 2:1 acid amine complexes are rather uncommon. In this case, a proton is transferred between one acid molecule and the amine to give an acid anion and an ammonium cation whilst the other carboxylic acid remains protonated. The species interact strongly via electrostatic forces and hydrogen bonds. In addition we note that the N atom of the ammonium group makes four close contacts to surrounding O atoms. Three of these are hydrogen bonds with neighbouring acid anions while the fourth does not involve a hydrogen atom but is directed towards the carbonyl O atom of the protonated acid. Each of the acid anion O atoms accepts two hydrogen bonds from adjacent N atoms. There is also evidence of short C—H⋯O contacts. There is disorder (occupancy ratio 0.51:0.49) in the alkyl chain of one of the carboxylic acid molecules.
Isolation of fla-lacZ fusions in Escherichia coli K-12: most fusions result in soluble beta-galactosidase

A series of fusions of flagellar genes to the lacZ gene was generated by insertion of Mu dII301 (Apr lac) bacteriophage into the genome of Escherichia coli. The beta-galactosidase activity in each resulting mutant was measured, and the location of the activity in the membrane, periplasmic, or cytoplasmic fraction of the cell was determined. There were three classes of mutants: those which had beta-galactosidase activity mainly in the membrane fraction, those which had it distributed in the soluble and membrane fractions, and those which had it in the cytoplasmic fraction only. The last, soluble-fraction-only, class was predominant in fla-lac gene fusions. In particular, the following mutants were shown to have beta-galactosidase activity in the membrane fractions: on the inner membrane, mutants with flaB fusions, and on the inner and outer membranes, mutants with flaA4850, flaM, and flaU4849 fusions. These results suggest that fla-lacZ gene fusions produce proteins which are able to detect the signals of the leader sequence and the membrane-anchoring region of the flagellar system.
Back EMF calculations for axial-gap permanent magnet synchronous motors (AGPMSM) with disc magnets

Axial-gap permanent magnet synchronous motors (AGPMSM) with disc magnets have been presented as a viable candidate for high speed traction drive applications in electric or hybrid electric vehicles. In this paper, back emf equation for an AGPMSM is derived and it is overlapped with the measured back emf for verification purposes
Development, differentiation, and phenotypic heterogeneity of murine tissue macrophages

In murine ontogeny, macrophage precursor cells develop in the yolk sac and fetal liver. Primitive macrophages also appear in the yolk sac, migrate to various tissues, and differentiate into several fetal macrophage populations. Because the development of the monocytic cell lineage is incomplete in the early stage of fetal hematopoiesis, primitive/fetal macrophages are considered to originate from granulocyte‐macrophage colony‐forming cells or earlier macrophage precursors, bypassing the early monocytic cell series. In adult mice rendered severely monocytopenic by administration of strontium‐89, resident macrophages are maintained by self‐renewal. In contrast, administration of liposome‐encapsulated dichloromethylene diphosphonate (clodronate) results in the elimination of various tissue macrophage populations. The repopulation of affected macrophages is dependent on the increase of precursors in the liver and spleen during the period of macrophage depletion. Such precursors reconstitute heterogeneous macrophage subpopulations. In mice homozygous for the osteopetrosis (op) mutation, the absence of macrophage colony‐stimulating factor (M‐CSF) activity results in a deficiency of monocytes and monocyte‐derived macrophages. However, immature macrophages are present in various tissues. Administration of M‐CSF to op/op mice induces the increased proliferative capacity and the morphological maturation of macrophages. However, the responses of individual tissue macrophage subpopulations to M‐CSF are different. These results indicate that macrophage development, differentiation, and proliferation are regulated by the tissue microenvironment including the in situ production of macrophage growth factors in both fetal and adult life.
Language Independent End-to-End Architecture For Joint Language and Speech Recognition

End-to-end automatic speech recognition (ASR) can significantly reduce the burden of developing ASR systems for new languages, by eliminating the need for linguistic information such as pronunciation dictionaries. This also creates an opportunity, which we fully exploit in this paper, to build a monolithic multilingual ASR system with a language-independent neural network architecture. We present a model that can recognize speech in 10 different languages, by directly performing grapheme (character/chunked-character) based speech recognition. The model is based on our hybrid attention/connectionist temporal classification (CTC) architecture which has previously been shown to achieve the state-of-the-art performance in several ASR benchmarks. Here we augment its set of output symbols to include the union of character sets appearing in all the target languages. These include Roman and Cyrillic Alphabets, Arabic numbers, simplified Chinese, and Japanese Kanji/Hiragana/Katakana characters (5,500 characters in all). This allows training of a single multilingual model, whose parameters are shared across all the languages. The model can jointly identify the language and recognize the speech, automatically formatting the recognized text in the appropriate character set. The experiments, which used speech databases composed of Wall Street Journal (English), Corpus of Spontaneous Japanese, HKUST Mandarin CTS, and Voxforge (German, Spanish, French, Italian, Dutch, Portuguese, Russian), demonstrate comparable/superior performance relative to language-dependent end-to-end ASR systems. IEEE Workshop on Automatic Speech Recognition and Understanding (ASRU) This work may not be copied or reproduced in whole or in part for any commercial purpose. Permission to copy in whole or in part without payment of fee is granted for nonprofit educational and research purposes provided that all such whole or partial copies include the following: a notice that such copying is by permission of Mitsubishi Electric Research Laboratories, Inc.; an acknowledgment of the authors and individual contributions to the work; and all applicable portions of the copyright notice. Copying, reproduction, or republishing for any other purpose shall require a license with payment of fee to Mitsubishi Electric Research Laboratories, Inc. All rights reserved. Copyright c © Mitsubishi Electric Research Laboratories, Inc., 2017 201 Broadway, Cambridge, Massachusetts 02139 LANGUAGE INDEPENDENT END-TO-END ARCHITECTURE FOR JOINT LANGUAGE IDENTIFICATION AND SPEECH RECOGNITION Shinji Watanabe, Takaaki Hori, and John R. Hershey Mitsubishi Electric Research Laboratories (MERL), Cambridge MA, USA
Computational Insights Into Voltage Dependence of Polyamine Block in a Strong Inwardly Rectifying K+ Channel

Inwardly rectifying potassium (KIR) channels play important roles in controlling cellular excitability and K+ ion homeostasis. Under physiological conditions, KIR channels allow large K+ influx at potentials negative to the equilibrium potential of K+ but permit little outward current at potentials positive to the equilibrium potential of K+, due to voltage dependent block of outward K+ flux by cytoplasmic polyamines. These polycationic molecules enter the KIR channel pore from the intracellular side. They block K+ ion movement through the channel at depolarized potentials, thereby ensuring, for instance, the long plateau phase of the cardiac action potential. Key questions concerning how deeply these charged molecules migrate into the pore and how the steep voltage dependence arises remain unclear. Recent MD simulations on GIRK2 (=Kir3.2) crystal structures have provided unprecedented details concerning the conduction mechanism of a KIR channel. Here, we use MD simulations with applied field to provide detailed insights into voltage dependent block of putrescine, using the conductive state of the strong inwardly rectifying K+ channel GIRK2 as starting point. Our µs long simulations elucidate details about binding sites of putrescine in the pore and suggest that voltage-dependent rectification arises from a dual mechanism.
Targeted Transgene Expression in Cholinergic Interneurons in the Monkey Striatum Using Canine Adenovirus Serotype 2 Vectors

The striatum, the main input structure of the basal ganglia, is critical for action selection and adaptive motor control. To understand the neuronal mechanisms underlying these functions, an analysis of microcircuits that compose the striatum is necessary. Among these, cholinergic interneurons (ChIs) provide intrinsic striatal innervation whose dysfunction is implicated in neuropsychiatric diseases, such as Parkinson’s disease and Tourette syndrome. The ability to experimentally manipulate the activity of ChIs is critical to gain insights into their contribution to the normal function of the striatum and the emergence of behavioral abnormalities in pathological states. In this study, we generated and tested CAV-pChAT-GFP, a replication-defective canine adenovirus type 2 (CAV-2) vector carrying the green fluorescent protein (GFP) sequence under the control of the human choline acetyltransferase (ChAT) promoter. We first tested the potential specificity of CAV-pChAT-GFP to label striatal ChIs in a rat before performing experiments on two macaque monkeys. In the vector-injected rat and monkey striatum, we found that GFP expression preferentially colocalized with ChAT-immunoreactivity throughout the striatum, including those from local circuit interneurons. CAV-2 vectors containing transgene driven by the ChAT promoter provide a powerful tool for investigating ChI contributions to circuit function and behavior in nonhuman primates.
Generación de un modelo mediante el uso de redes neuronales artificiales para la detección de mastitis en vacas lecheras del INTA Estación Experimental Agropecuaria Rafaela

Resumen. El presente informe corresponde al Trabajo Final de Grado de la carrera Ingenieria en Informatica de la Universidad Catolica de Santiago del Estero, Departamento Academico Rafaela. El objetivo del trabajo era facilitar la deteccion de mastitis en vacas lecheras del Instituto Nacional de Tecnologia Agropecuaria Estacion Experimental Agropecuaria Rafaela, utilizando herramientas de software, mas especificamente, redes neuronales artificiales.
Crystallographic and biochemical investigation of the lead(II)-catalyzed hydrolysis of yeast phenylalanine tRNA.

X-ray diffraction data from monoclinic crystals of yeast tRNAPhe soaked in dilute lead(II) acetate solutions at pH 5.0 and at pH 7.4 have been collected to a resolution of 3 A, and the Pb(II) binding sites have been obtained by difference Fourier analyses. The same three Pb(II) binding sites are observed at both of these pH values. At pH 7.4 an extra peak of negative electron density appears on the difference map close to one of the Pb(II) binding sites and at the position of phosphate-18, indicating cleavage of the sugar-phosphate-chain between residues D-17 and G-18 of the tRNAPhe molecule in this derivative. Chain scission does not occur to any observable extent in the structure at pH 5.0, and we have, therefore, a picture of the reactants (at pH 5.0) and products (at pH 7.4) of this cleavage reaction. Polyacrylamide gel electrophoresis as well as sequencing experiments confirms the cleavage of the tRNAPhe molecule into one-fourth and three-fourth fragments, with the shorter fragment consisting essentially of residues G-1 through D-17 while the larger fragment contains residues G-18 through A-76. End-group analyses suggest a ribose cyclic 2',3'-phosphate at D-17 of the one-fourth fragment with a 5'-OH at G-18 of the three-fourth fragment. Cleavage of the tRNAPhe molecule does not occur in the absence of Pb(II), and the proximity of one of these metal ions to the cleavage site strongly implicates this metal ion in the cleavage reaction. Consideration of several possible mechanisms for the reaction, taking into account the biochemical and crystallographic facts presented above, suggests that the cleavage involves removal of the proton from the 2'-OH of ribose-17 by a Pb(II)-bound hydroxyl group. Subsequent nucleophilic attack of the resulting 2'-O- on the phosphorus atom of phosphate-18, presumably through a pentacoordinate phosphorus cyclic intermediate (as in the action of pancreatic ribonuclease A), results in chain scission. It cannot be decided whether the displacement, within the pentacoordinate intermediate, proceeds via an in-line or adjacent pathway, but an exploration of the likelihood of either pathway is presented. Strand cleavage at the particular site occurs fortuitously because the aquo Pb(II) ion binds at the correct distance and presumably in such a manner as to present a hydroxyl group in the correct orientation to effect the proton abstraction. (ABSTRACT TRUNCATED AT 400 WORDS)
Sentencing risk: history of incarceration and HIV/STD transmission risk behaviours among Black men who have sex with men in Massachusetts

This study investigated the role of incarceration in HIV/STD risk among 197 Black men who have sex with men in Massachusetts, USA. More than half (51%) reported a history of incarceration (28% < 90 days in jail/prison; 23% ≥ 90 days in jail/prison). Multivariable logistic regression models adjusted for age and sexual orientation examined associations between demographic, behavioural, social-psychological and cultural factors and incarceration history. Factors associated with < 90 days of incarceration were: unprotected sex with a man, STD history, injection drug use and substance abuse treatment. Factors associated with ≥ 90 days of incarceration were: unprotected sex with a woman, crack use during sex, STD history, injection drug use, substance abuse treatment, depressive symptoms, post-traumatic stress symptoms, HIV fatalism and social capital. Black men who have sex with men with incarceration histories may be at increased risk for HIV/STDs compared to those without such histories. HIV prevention efforts that focus on individual risk and cultural-contextual issues among Black men who have sex with men are warranted.
Increased p53 signaling impairs neural differentiation causing HUWE1-promoted intellectual disabilities

Essential E3 ubiquitin ligase HUWE1 (HECT, UBA and WWE domain containing 1) regulates key factors, as p53. Mutations in HUWE1 have been associated with neurodevelopmental X-linked intellectual disabilities (XLIDs), however the pathomechanism at the onset of heterogenous XLIDs remains unknown. In this work, we identify p53 signaling as the process hyperactivated in lymphoblastoid cells from patients with HUWE1-promoted XLIDs. The hiPSCs-based modeling of the severe HUWE1-promoted XLID, the Juberg Marsidi syndrome (JMS), reviled majorly impaired neural differentiation, accompanied by increased p53 signaling. The impaired differentiation results in loss of cortical patterning and overall undergrowth of XLID JMS patient-specific cerebral organoids, thus closely recapitulating key symptoms, as microcephaly. Importantly, the neurodevelopmental potential of JMS hiPSCs is successfully rescued by restoring p53 signaling, upon reduction of p53 levels. In summary, our findings indicate that increased p53 signaling leads to impaired neural differentiation and is the common cause of neurodevelopmental HUWE1-promoted XLIDs.