Miracle-dz/UniFAR-FTUs huggingface dataset:
nventory of veterinary syndromic surveillance initiatives in urope ( TripleS project ) : Current situation and perspectives

Within the current context that favours the emergence of new diseases, syndromic surveillance (SyS) appears increasingly more relevant tool for the early detection of unexpected health events. The Triple-S project (Syndromic Surveillance Systems in Europe), co-financed by the European Commission, was launched in September 2010 for a three year period to promote both human and animal health SyS in European countries. Objectives of the project included performing an inventory of current and planned European animal health SyS systems and promoting knowledge transfer between SyS experts. This study presents and discusses the results of the Triple-S inventory of European veterinary SyS initiatives. European SyS systems were identified through an active process based on a questionnaire sent to animal health experts involved in SyS in Europe. Results were analyzed through a descriptive analysis and a multiple factor analysis (MFA) in order to establish a typology of the European SyS initiatives. Twenty seven European SyS systems were identified from twelve countries, at different levels of development, from project phase to active systems. Results of this inventory showed a real interest of European countries for SyS but also highlighted the novelty of this field. This survey highlighted the diversity of SyS systems in Europe in terms of objectives, population targeted, data providers, indicators monitored. For most SyS initiatives, statistical analysis of surveillance results was identified as a limitation in using the data. MFA results distinguished two types of systems. The first one belonged to the private sector, focused on companion animals and had reached a higher degree of achievement. The second one was based on mandatory collected data, targeted livestock species and is still in an early project phase. ∗ Corresponding author at: Unité Epidémiologie, Agence nationale de sécurité sanitaire de l’alimentation, de l’environnement et du travail (Anses), 31, venue Tony Garnier, F69364 Lyon Cedex 07, France. Tel. : +33 04 78 61 44 17; fax: +33 04 78 61 91 45. E-mail address: celine.dupuy@anses.fr (C. Dupuy). 167-5877/$ – see front matter © 2013 Elsevier B.V. All rights reserved. ttp://dx.doi. org/10.1016/j.prevetmed. 2013.06. 005 C. Dupuy et al. / Preventive Veterinary Medicine 111 (2013) 220– 229 221 The exchange of knowledge between human and animal health sectors was considered useful to enhance SyS. In the same way that SyS is complementary to traditional surveillance, synergies between human and animal health SyS could be an added value, most notably to s, sensi enhance timelines
A MULTI-WAVELENGTH STUDY OF LOW-REDSHIFT CLUSTERS OF GALAXIES. II. ENVIRONMENTAL IMPACT ON GALAXY GROWTH

Galaxy clusters provide powerful laboratories for the study of galaxy evolution, particularly the origin of correlations of morphology and star formation rate (SFR) with density. We construct visible to MIR spectral energy distributions of galaxies in eight low-redshift (z < 0.3) clusters and use them to measure stellar masses and SFRs as a function of environment. A partial correlation analysis indicates that the SFRs of star-forming galaxies (SFGs) depend strongly on M* (>99% confidence) with no dependence on R/R200 or projected local density at fixed mass. A merged sample of galaxies from the five best measured clusters shows 〈SFR〉∝(R/R200)1.1 ± 0.3 for galaxies with R/R200 ⩽ 0.4. A decline in the fraction of SFGs toward the cluster center contributes most of this effect, but it is accompanied by a reduction in 〈SFR〉 for SFGs with R ⩽ 0.1 R200. The increase in the fraction of SFGs toward larger R/R200 and the isolation of SFGs with reduced SFRs near the cluster center are consistent with the truncation of star formation by ram-pressure stripping, as is the tendency for more massive SFGs to have higher SFRs. We conclude that stripping is more likely than slower processes to drive the properties of SFGs with R < 0.4 R200 in clusters. We also find that galaxies near the cluster center are more massive than galaxies farther out in the cluster at ∼3. 5σ, which suggests that dynamical relaxation significantly impacts the distribution of cluster galaxies as the clusters evolve.
Gratitude versus Entitlement: A Dual Process Model of the Profitability Implications of Customer Prioritization

Customer prioritization strategies, which focus a firm's efforts on its most important customers, are expected to improve account profitability. Anecdotal evidence suggests, however, that such strategies may also undermine account profitability by inducing customers to become overly demanding. Building on social exchange theory, this research evaluates these competing perspectives across two field studies and finds that prioritization is best understood as a double-edged sword. Specifically, the results reveal that prioritization efforts initiate both a gratitude-driven process, which enhances sales and profit, and an entitlement-driven process, which increases service costs and reduces profit. Importantly, the findings indicate that prioritization tactics differ in the extent to which they trigger these competing processes and thus in their ability to influence account profitability. Finally, the results also reveal that critical moderators (competitive intensity and prioritization transparency) determine the extent to which the entitlement-driven process undermines the gratitude-driven process. For managers, the findings suggest that both the tactics employed and moderating conditions determine whether prioritization has a positive, negative, or negligible effect on prioritized accounts’ profitability.
Hydrogen‐rich water regulates effects of ROS balance on morphology, growth and secondary metabolism via glutathione peroxidase in Ganoderma lucidum

Ganoderma lucidum is one of the most important medicinal fungi, but the lack of basic study on the fungus has hindered the further development of its value. To investigate the roles of the redox system in G. lucidum, acetic acid (HAc) was applied as a reactive oxygen species (ROS) stress inducer, and hydrogen-rich water (HRW) was used to relieve the ROS stress in this study. Our results demonstrate that the treatment of 5% HRW significantly decreased the ROS content, maintained biomass and polar growth morphology of mycelium, and decreased secondary metabolism under HAc-induced oxidative stress. Furthermore, the roles of HRW were largely dependent on restoring the glutathione system under HAc stress in G. lucidum. To provide further evidence, we used two glutathione peroxidase (GPX)-defective strains, the gpxi strain, the mercaptosuccinic acid (MS, a GPX inhibitor)-treated wide-type (WT) strain, and gpx overexpression strains for further research. The results show that HRW was unable to relieve the HAc-induced ROS overproduction, decreased biomass, mycelium morphology change and increased secondary metabolism biosynthesis in the absence of GPX function. The gpx overexpression strains exhibited resistance to HAc-induced oxidative stress. Thus, we propose that HRW regulates morphology, growth and secondary metabolism via glutathione peroxidase under HAc stress in the fungus G. lucidum. Furthermore, our research also provides a method to study the ROS system in other fungi.
Fault estimation for neutral systems with time-varying delay using observer

This paper concerns the problem of fault estimation for neutral systems with time-varying delay using observer. In fact, compared with the constant delay systems, time-varying delay systems are more common. Based on the fault estimation for neutral delay systems, the paper applies a fault estimation algorithm to neutral systems with time-varying delay based on observer, which can improve the performance of fault estimation. Secondly, the paper also provides a delay-dependent criterion, it is very important especially for small delay systems. Thirdly, the paper describes the calculation steps in detail that use of linear matrix inequality (LMI) technique. Finally, in order to verify the efficiency, the paper presents several simulation results which are obtained by using Simulink tool.
Unaltered negative selection and Treg development of self‐reactive thymocytes in TCR transgenic Fyn‐deficient mice

The tyrosine kinase Fyn has been implicated as playing an important role in the generation of both stimulatory and inhibitory signaling events induced by TCR engagement. To assess the role of Fyn for antigen‐driven negative selection and Treg development, which are both dependent on the strength and nature of TCR signaling, we generated mice that co‐express the transgenes for OVA and the OT‐II TCR, which recognizes a peptide from OVA. In mice expressing both transgenes, negative selection, Treg development in the thymus, and the number of Treg in the periphery were each unaffected by ablation of Fyn. Moreover, fyn−/− Treg were functional, as assessed in vitro. We further tested the role of Fyn for the adaptor function of c‐Cbl, using mice containing a point mutation in c‐Cbl that abolishes its E3 ubiquitin ligase function but maintains its adaptor function. The functional and signaling properties of this mutant c‐Cbl were unaltered in fyn−/− thymocytes. Combined, these data indicate that Fyn was not required for the induction of central tolerance by negative selection, the adaptor protein role of c‐Cbl, or the normal development and function of Treg.
Comparative Vertebrate Neuroanatomy: Evolution and Adaptation

Immunology: A Short Course, Third Edition is an extensively revised and updated version of their previous edition. According to the authors, every chapter has been either extensively revised or rewritten since the 1991 publication of their second edition. Much of the updated information is in the realm of molecular mechanisms of lymphocyte action which have been elucidated in the past five years. The book is organized as in the previous edition, following the standard plan of conventional immunology texts. However, each chapter is condensed to what would be the equivalent length of preparatory reading for a lecture, treating essential topics fairly well without losing the reader in esoteric details. The authors have followed the theory of the architect, Mies van der Rohe, that "less is more. " In the words of the authors, "Immunology deals with understanding how the body distinguishes between what is self and what is 'nonself; all the rest is technical detail. " The book maintains this relative focus throughout, although details judged pertinent are appropriately covered. The end of each chapter includes a summary of important topics or concepts, references for further reading, and very useful review questions and answers which quiz the reader on pertinent information, serving as a check to make sure the reader has understood the essentials of the chapter. In this sense, the book serves not only as a very readable introduction to immunology, but would also be valuable for any student wanting a "review-of-essentials" text. There are sections covering immunodeficiency, immunotherapy, hypersensitivity, and tumor immunology, in addition to transfusion and transplantation immunology. Furthermore, some clinical situations are presented which help to synthesize the material. The diagrams, histology, and occasional electron micrograph wellillustrate the important concepts. This book would make a great introductory text for the student interested in the essentials of immunology. The format of the book, complete with review questions, lends itself well to self-study for the student or professional who would like to obtain a working knowledge of the field. It also provides a valuable resource for those readers wanting to refresh themselves on the essentials of immunology.
Wideband and high-order multi-user spatial multiplexing transmission with massive MIMO for future radio access

Massive MIMO is one of the promising technologies to be employed in the next generation mobile communication systems. Multi-user transmission is the nature of massive MIMO due to the high order of degree of freedoms and large beamforming gain provided by the large scale antenna arrays mounted at the base station side. Considering this nature and the characteristics of massive MIMO channels, we propose wideband and high-order multi-user MIMO transmission mode for future radio access. Under such transmission mode, the simple but efficient scheduling strategies, e.g., all-user on all-subband scheduling, can be considered for downlink scheduling to obtain the potential gain of massive MIMO. System-level performance and detailed analysis on the characteristics of channel state are provided through simulations, which show the advantages of proposed wideband and high-order MU-MIMO transmission mode for massive MIMO systems.
The Design and Implementation of a Non-Volatile Memory Database Management System

This dissertation explores the implications of non-volatile memory (NVM) for database management systems (DBMSs). The advent of NVM will fundamentally change the dichotomy between volatile memory and durable storage in DBMSs. These new NVM devices are almost as fast as DRAM, but all writes to it are potentially persistent even after power loss. Existing DBMSs are unable to take full advantage of this technology because their internal architectures are predicated on the assumption that memory is volatile. With NVM, many of the components of legacy DBMSs are unnecessary andwill degrade the performance of the data intensive applications. We present the design and implementation of a new DBMS tailored specifically for NVM. The dissertation focuses on three aspects of a DBMS: (1) logging and recovery, (2) storage management, and (3) indexing. Our primary contribution in this dissertation is the design of a new logging and recovery protocol, called write-behind logging, that improves the availability of the system bymore than two orders of magnitude compared to the ubiquitous write-ahead logging protocol. Besides improving availability, we demonstrate that write-behind logging extends the lifetime and increases the the space utilization of the NVM device. Second, we propose a new storage engine architecture that leverages the durability and byte-addressability properties of NVM to avoid unnecessary data duplication. Third, the dissertation presents the design of a range index tailored for NVM that supports near-instantaneous recovery without requiring specialpurpose recovery code.
THE CLOUD UNIVERSITY PLATFORM: NEW CHALLENGES OF THE CO-OPERATION IN THE EUROPEAN UNIVERSITY SYSTEM

Abstract Many experts have recently noted that cloud computing is a key driver of digital technology and ubiquitous revolution. Cloud computing is Internet-based computing, whereby shared resources, software, and information are provided to computers and other devices on demand, like the electricity grid. In the paper we concentrate on “clouds” in the context of universities. The aim of paper is to create the conceptual framework of the cloud university platform. The concept of European Cloud University is a new idea to make universities to be more competitive in a global setting and provide a broad set of educational services to customers. It provides a large-scale platform for exchange of information, views, mutual learning and practical cooperation between innovation policy and innovation support actors with an interest in, and willingness to contribute to the improvement of the design, implementation and delivery of innovation policies and support measures. Keywords: Universities, co-operation, Europe, innovation systems, open innovation paradigm, ecosystems of innovation, cloud computing, innovation dynamics, life long learning.
The intention of Australian older workers to continue paid work: the impact of marital differences

This paper examines whether the impact of certain work-related factors on older workers' intention to continue paid work varies between couples and singles. Data were collected through a questionnaire survey of a sample of employees, aged 50 years and older, working in a large public sector organisation in Australia. Data analysis suggests that work-related factors that are significant for couples include 'interests outside of work', 'importance of work' and 'flexibility'. 'Interests outside of work' and 'flexibility' were also important factors for singles in their intentions to continue working. Analysis of the data demonstrated that a clearly identifiable work-related factor that provides a differentiation between couples and singles was 'importance of work' for couples. Given the ageing population and the issues related to future labour shortages (including the trend toward early retirement), there is a clear inference for management to develop new marital status specific policies and practices aimed expressly to increase the employment of older workers.
The elderly cancer patient: The interplay between age and clinical decision-making

Oncology affects millions of elderly patients. Despite this significant and growing population, there are few randomized trials in geriatric oncology. As a result, the treatment of this age group is often controversial. The physician often faces many unanswered questions regarding the best treatment strategy for his or her elderly patients. This article aims to demonstrate how the lack of research in the area of geriatric oncology represents a barrier to treatment decisions. Further, we will describe the interaction between age, comorbidity and cancer, and how these variables can affect treatment and outcomes in the elderly.
Positive-Feedback Level Shifter Logic for Large-Area Electronics

Positive-feedback Level Shifter (PLS) logic is proposed in this paper for the design of unipolar digital circuits manufactured at low temperature on foil using organic or metal-oxide semiconductors. Positive feedback and a suitable control voltage provide high gain and a symmetrical input-output characteristic even in presence of large TFT variations, enabling robust digital design. The measured gain improves from 13 dB in traditional Zero-Vgs inverters to 76 dB in PLS inverters; the average noise margin increases from 2.58 V (Zero-Vgs) to 6.82 V (PLS) at 20 V supply. Assuming that a positive noise margin for each gate is the only requirement to obtain a fully functional digital circuit, the maximum number of logic gates compatible with a 90% yield improves from 200 Zero-Vgs inverters to above 24 million PLS inverters. A 240-stage PLS shift-register exploiting 13,440 organic TFTs is indeed successfully measured. This is to the authors' knowledge the organic circuit with the highest transistor count ever demonstrated. The control voltage, always within the supply rails, enables automatic correction of the process variations using linear control circuits. The proposed approach will enable a strong increase in the complexity of large-area electronics on foil, with great benefit to applications like flexible displays and large-area sensing surfaces.
Characterization of dielectric properties of screen-printed MgTiO3-CaTiO3 composite thick films in the microwave frequency range

Dielectric characterization of MgTiO3, CaTiO3 and MgTiO3(x)-CaTiO3(1−x) composite thick films with different concentrations (x = 0.95, 0.50, and 0.20) in the microwave frequency range at room temperature is presented. The films were fabricated by screen-printed method with thickness between 105 and 165 µm. Dielectric constant values between 4.2 and 17.5 and loss tangents between 0.0064 and 0.0098 were measured for frequencies in the range from 3.22 to 3.89 GHz using the coplanar waveguide (CPW) resonators technique. A relationship between the concentration ratio of MTO-CTO in the films and the dielectric constant is also presented.
Customer Lifetime Value and the Austrian School Tradition

We examine the modern approach to customers as assets in its connection to the tradition of the Austrian Economic Theory. We revisit the concept of Customer Lifetime Value within a conceptual framework similar to a Misesian Evenly Rotating Economy. We argue that individual entrepreneurial action inside the market process plays a crucial role in determining the characteristics of customer assets. In our model of an Evenly Rotating Economy we show by means of a numerical example that a passive entrepreneurial attitude and a mechanistic application of the Customer Lifetime Value approach may result in destruction of Value of the Firm.
Shifting the genomic gold standard for the prokaryotic species definition

DNA-DNA hybridization (DDH) has been used for nearly 50 years as the gold standard for prokaryotic species circumscriptions at the genomic level. It has been the only taxonomic method that offered a numerical and relatively stable species boundary, and its use has had a paramount influence on how the current classification has been constructed. However, now, in the era of genomics, DDH appears to be an outdated method for classification that needs to be substituted. The average nucleotide identity (ANI) between two genomes seems the most promising method since it mirrors DDH closely. Here we examine the work package JSpecies as a user-friendly, biologist-oriented interface to calculate ANI and the correlation of the tetranucleotide signatures between pairwise genomic comparisons. The results agreed with the use of ANI to substitute DDH, with a narrowed boundary that could be set at ≈95–96%. In addition, the JSpecies package implemented the tetranucleotide signature correlation index, an alignment-free parameter that generally correlates with ANI and that can be of help in deciding when a given pair of organisms should be classified in the same species. Moreover, for taxonomic purposes, the analyses can be produced by simply randomly sequencing at least 20% of the genome of the query strains rather than obtaining their full sequence.