Miracle-dz/UniFAR-FTUs huggingface dataset:
Tools to support systematic reviews in software engineering: a feature analysis

Background The labour intensive and error prone nature of the systematic review process has led to the development and use of a range of tools to provide automated support. Aim The aim of this research is to evaluate a set of candidate tools that provide support for the overall systematic review process. Method A feature analysis is performed to compare and evaluate four candidate tools. Results Each of the candidates has some strengths and some weaknesses. SLuRp has the highest overall score and SLRTOOL has the lowest overall score. SLuRp scores well on process management features such as support for multiple users and document management and less well on ease of installation. Conclusions Although the tools do not yet support the whole systematic review process they provide a good basis for further development. We suggest a community effort to establish a set of features that can inform future tool development.
The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif

The RecQL4 helicase is involved in the maintenance of genome integrity and DNA replication. Mutations in the human RecQL4 gene cause the Rothmund–Thomson, RAPADILINO and Baller–Gerold syndromes. Mouse models and experiments in human and Xenopus have proven the N-terminal part of RecQL4 to be vital for cell growth. We have identified the first 54 amino acids of RecQL4 (RecQL4_N54) as the minimum interaction region with human TopBP1. The solution structure of RecQL4_N54 was determined by heteronuclear liquid–state nuclear magnetic resonance (NMR) spectroscopy (PDB 2KMU; backbone root-mean-square deviation 0.73 Å). Despite low-sequence homology, the well-defined structure carries an overall helical fold similar to homeodomain DNA-binding proteins but lacks their archetypical, minor groove-binding N-terminal extension. Sequence comparison indicates that this N-terminal homeodomain-like fold is a common hallmark of metazoan RecQL4 and yeast Sld2 DNA replication initiation factors. RecQL4_N54 binds DNA without noticeable sequence specificity yet with apparent preference for branched over double-stranded (ds) or single-stranded (ss) DNA. NMR chemical shift perturbation observed upon titration with Y-shaped, ssDNA and dsDNA shows a major contribution of helix α3 to DNA binding, and additional arginine side chain interactions for the ss and Y-shaped DNA.
Structural and visual similarity learning for Web page archiving

We present in this paper a Web page archiving approach combining image and structural techniques. Our main goal is to learn a similarity between Web pages in order to detect whether successive versions of pages are similar or not. Our system is based on a visual similarity measure designed for Web pages. Combined with a structural analysis of Web page source codes, a supervised feature selection method adapted to Web archiving is proposed. Experiments on real Web archives are reported including scalability issues.
Multi-scale analysis of warm extremes over China

Multi-scale features of warm extremes over China from 1961 to 2002 are evaluated using daily minimum and maximum temperature data. Different time scales of regional features of warm extremes are performed using rotated empirical orthogonal function (REOF) analysis and time scale departure methods. Clearly, significant differences are found in multi-scale of warm extremes. Significant increasing linear trends are detected in Northeast China, Inner Mongolia, northwestern part of Xinjiang, and southwestern China. However, in middle and lower reaches of Yangtze River, southern China and lower reaches of Yellow River basin, the linear trend is not remarkable, but the interannual pattern is the leading part, with several extreme peaks. The links with global temperature anomalies are studied, focusing in northeastern China and in middle and lower reaches of Yangtze River. It is found that the extreme indices show largest correlations with temperature anomalies in the Pacific Ocean. We detect that in northeastern and inland areas, high-related regions of frequency of warm extremes and the global temperature anomalies are broader, while the high-related area is smaller in the middle and lower reaches of the Yangtze River and the coastal regions.
A Qualitative Study of Vietnamese Parental Involvement and their High Academic Achieving Children

Vietnamese parents in the current study do not belong to school parent organizations, rarely visit the school or contact the teachers. However, the ten students in this qualitative investigation of parent interviews performed well academically, completing their high school educations with a 4.0 G.P.A. This article presents an examination of how Vietnamese parents acculturate their children, leading to high academic achievement without using the traditionally defined parental involvement methods. Specifically, Vietnamese families provided a structured home learning environment, high academic expectations, attention, love and emotional support, traditional family values, stories of cultural heritage and parental sacrifice, and control of children's social lives. ______________________________________________________________________________
Preterm Birth in Caucasians Is Associated with Coagulation and Inflammation Pathway Gene Variants

Spontaneous preterm birth (<37 weeks gestation—PTB) occurs in ∼12% of pregnancies in the United States, and is the largest contributor to neonatal morbidity and mortality. PTB is a complex disease, potentially induced by several etiologic factors from multiple pathophysiologic pathways. To dissect the genetic risk factors of PTB a large-scale high-throughput candidate gene association study was performed examining 1536 SNP in 130 candidate genes from hypothesized PTB pathways. Maternal and fetal DNA from 370 US Caucasian birth-events (172 cases and 198 controls) was examined. Single locus, haplotype, and multi-locus association analyses were performed separately on maternal and fetal data. For maternal data the strongest associations were found in genes in the complement-coagulation pathway related to decidual hemorrhage in PTB. In this pathway 3 of 6 genes examined had SNPs significantly associated with PTB. These include factor V (FV) that was previously associated with PTB, factor VII (FVII), and tissue plasminogen activator (tPA). The single strongest effect was observed in tPA marker rs879293 with a significant allelic (p = 2.30×10−3) and genotypic association (p = 2.0×10−6) with PTB. The odds ratio (OR) for this SNP was 2.80 [CI 1.77–4.44] for a recessive model. Given that 6 of 8 markers in tPA were statistically significant, sliding window haplotype analyses were performed and revealed an associating 4 marker haplotype in tPA (p = 6.00×10−3). The single strongest effect in fetal DNA was observed in the inflammatory pathway at rs17121510 in the interleukin-10 receptor antagonist (IL-10RA) gene for allele (p = 0.01) and genotype (p = 3.34×10−4). The OR for the IL-10RA genotypic additive model was 1.92 [CI 1.15–3.19] (p = 2.00×10−3). Finally, exploratory multi-locus analyses in the complement and coagulation pathway were performed and revealed a potentially significant interaction between a marker in FV (rs2187952) and FVII (rs3211719) (p<0.001). These results support a role for genes in both the coagulation and inflammation pathways, and potentially different maternal and fetal genetic risks for PTB.
AtsPLA2-α nuclear relocalization by the Arabidopsis transcription factor AtMYB30 leads to repression of the plant defense response

The hypersensitive response (HR), characterized by a rapid and localized cell death at the inoculation site, is one of the most efficient resistance reactions to pathogen attack in plants. The transcription factor AtMYB30 was identified as a positive regulator of the HR and resistance responses during interactions between Arabidopsis and bacteria. Here, we show that AtMYB30 and the secreted phospholipase AtsPLA2-α physically interact in vivo, following the AtMYB30-mediated specific relocalization of AtsPLA2-α from cytoplasmic vesicles to the plant cell nucleus. This protein interaction leads to repression of AtMYB30 transcriptional activity and negative regulation of plant HR. Moreover, Atspla2-α mutant plants are more resistant to bacterial inoculation, whereas AtsPLA2-α overexpression leads to decreased resistance, confirming that AtsPLA2-α is a negative regulator of AtMYB30-mediated defense. These data underline the importance of cellular dynamics and, particularly, protein translocation to the nucleus, for defense-associated gene regulation in plants.
An Evaluation of Some Programmes for Children with Autistic Spectrum Disorder in Auckland: Opportunities, Contingencies, and Illusions

VII EXECUTIVE SUMMARY . IX STUDY 1.X BACKGROUND . X THE PROGRAMMES.X AAPTC . X MAINSTREAM . XI HOME-PROGRAMME . XI THE CHILDREN WHO PARTICIPATED . XI METHODOLOGY. XII RESULTS OF STUDY 1 . XII STUDY 2. XIII METHODOLOGY. XIII RESULTS OF STUDY 2 . XIV STUDY 3.XIV METHODOLOGY. XIV RESULTS OF STUDY 3 . XIV STUDY 4. XV METHODOLOGY. XV RESULTS OF STUDY 4 . XV EVALUATING PROGRAMME EFFECTIVENESS.XVI ISSUES FOR THE EDUCATION OF CHILDREN WITH ASD IN NEW ZEALAND . XVII CONCLUSION . XVIII AN EVALUATION OF SOME PROGRAMMES FOR CHILDREN WITH AUTISTIC SPECTRUM DISORDER IN AUCKLAND: OPPORTUNITIES, CONTINGENCIES, AND ILLUSIONS.1
Signal Timing across the Macaque Visual System Tories (reviewed by Nowak and Bullier 1998) or Directly In

The onset latencies commonly made indirect comparisons are often confounded of single-unit responses evoked by flashing visual stimuli were due to differences in experimental and analytic methodology. measured in the parvocellular (P) and magnocellular (M) layers In addition, the visual response latencies of several key areas of the dorsal lateral geniculate nucleus (LGNd) and in cortical in macaque, such as the M and P layers of LGNd, middle visual areas V1, V2, V3, V4, middle temporal area (MT), medial temporal area (MT), and V4 have gone largely unstudied superior temporal area (MST), and in the frontal eye field (FEF) (but see Maunsell 1987; Raiguel et al. 1989). To our knowl-in individual anesthetized monkeys. Identical procedures were carried out to assess latencies in each area, often in the same monkey, edge, no visual onset latency data have been reported for thereby permitting direct comparisons of timing across areas. This macaque area V3 or for medial superior temporal area study presents the visual flash-evoked latencies for cells in areas (MST) or frontal eye field (FEF) in the anesthetized prepa-where such data are common (V1 and V2), and are therefore a ration (for awake macaque data, see Kawano et al. 1994; good standard, and also in areas where such data are sparse (LGNd Schall 1991; Thompson et al. 1996). This study was con-M and P layers, MT, V4) or entirely lacking (V3, MST, and FEF ducted to obtain visual response latencies in areas that have in anesthetized preparation). Visual-evoked onset latencies were, received little or no attention to date and to provide a direct on average, 17 ms shorter in the LGNd M layers than in the LGNd comparison of single-unit visual response latencies recorded P layers. Visual responses occurred in V1 before any other cortical from multiple cortical areas of individual monkeys under area. The next wave of activation occurred concurrently in areas the same stimulus presentation and animal preparation con-V3, MT, MST, and FEF. Visual response latencies in areas V2 and V4 were progressively later and more broadly distributed. ditions. These differences in the time course of activation across the dorsal and ventral streams provide important temporal constraints on theo-V4, MT, MST, and FEF in four paralyzed, anesthetized macaque monkeys using standard surgical and single-unit recording tech-Accurate knowledge of the response latency of neurons niques consistent with Society for Neuroscience and National Insti-across the visual system is necessary for the development …
IT Infrastructure for Providing Energy-as-a-Service to Electric Vehicles

Plugin Hybrid Electric Vehicles (PHEVs) are set to be the defining trend in road transportation for the 21st century. Unfortunately, the process of charging a large number of PHEVs will put a prohibitive amount of stress on conventional power grids. As per current estimates, it will not be possible to satisfy the peak demand of charging millions of PHEVs with current infrastructure. Additionally, to ensure stability of the power grid, the demand needs to be closely matched with supply all the time. This is difficult to ensure in a dynamic scenario like PHEV charging, where it is not possible to predict the load in the future. This problem is further complicated by the introduction of intermittent sources of alternate energy like wind power. This paper proposes an IT infrastructure for managing energy usage of PHEVs. The paper introduces a generalized currency of energy called a token, which entitles its owner to produce or consume a certain amount of electrical energy. Furthermore, the paper propose an IT infrastructure to manage tokens produced by millions of PHEVs and power stations. Simulation results for the system that consider the behavior of millions of PHEVs using data in prior work and traces from the Australian power grid for the last five years are also presented.
Mechanism of electrical enhancement of efficacy of antibiotics in killing biofilm bacteria

The bioelectric effect, in which electric fields are used to enhance the efficacy of biocides and antibiotics in killing biofilm bacteria, has been shown to reduce the very high concentrations of these antibacterial agents needed to kill biofilm bacteria to levels very close to those needed to kill planktonic (floating) bacteria of the same species. In this report, we show that biofilm bacteria are readily killed by an antibiotic on all areas of the active electrodes and on the surfaces of conductive elements that lie within the electric field but do not themselves function as electrodes. Considerations of electrode geometry indicate that very low (< 100 microA/cm2) current densities may be effective in this electrical enhancement of antibiotic efficacy against biofilm bacteria, and flow experiments indicate that this bioelectric effect does not appear to depend entirely on the possible local electrochemical generation of antibacterial molecules or ions. These data are expected to facilitate the use of the bioelectric effect in the prevention and treatment of device-related bacterial infections that are caused by bacteria that grow in biofilms and thereby frustrate antibiotic chemotherapy.
Dual-power-path RF-DC multi-output power management unit for RFID tags

A dual-power-path (DPP) RF-DC topology is employed to design the power management unit for an EPC C1 G2 RFID tag using a 0. 18µm CMOS process with 7 output voltages for signal processing blocks and OTP memory. The DPP technique splits the rectifier and reconfigures the RF-DC circuits depending on the state of input power, which saves storage capacitor size without sacrificing efficiency, or alternatively, improves efficiency without additional capacitance.
Book Review: The Development of the Ego: Implications for Personality Theory, Psychopathology, and the Psychotherapeutic Process.

BECKER, E. (1973). The Denialof Death. New York: Free Press. COLARUSSO. C. A. & NEMIROFF. R. A. (1981). Adult Development: A New Dimension in Psychodynamic Theory and Practice. New York: Plenum. LASCH. C. (1979). The Culture of Narcissism. New York: Norton. LEVIN, F. M. (1991). Mapping the Mind: The Intersection of Psychoanalysis and Neuroscience. Hillsdale, NJ: Analytic Press. NEMIROFF. R. A. & COLARUSSO. C. A. (1985). TheRaceAgainstTime: Psychotherapyand Psychoanalysis in theSecond Half of Life. New York: Plenum. ROOSE, S. P. & PARnES. H. (1989). The middle years: biological considerations. In NewPsychoanalytic Perspectives, ed.J,Oldham & R. Liebert. New Haven, CT: Yale Univ. Press, pp. 179-190.
Effects of Three Caregiver Interventions: Support, Educational Literature, and Creative Movement

The primary focus of this study is to compare the effectiveness of three distinct intervention techniques in relieving some of the stress experienced by midlife daughters' caregiving for their frail mothers. The three techniques are: (a) a home-based literature “tip of the week” group, (b) a caregiver's support group, and (c) a creative-movement group. Based on a review of caregiving literature, no other studies have utilized a home-based literature intervention or a creative-movement intervention with midlife daughters providing informal care to frail mothers. As part of the weekly assessment evaluation, participants were asked to rate how helpful the previous week's session was with respect to five mental health variables: irritability, depression, anxiety, stress, and concentration. Overall, the support-based group had higher average scores for each of the five mental health variables and the highest overall mental health score. Future research and promising applications of future intervention programs are discussed.
Examining Asian Women's Motivations to Undergo Breast Cancer Screening

Purpose: This study utilizes Protection Motivation Theory as a theoretical framework to predict women’s intentions to go for mammogram screening in Singapore, a country with the highest incidence of breast cancer in Asia. Materials and Methods: A questionnaire centered on the theoretical predictive model of early detection behavior was developed to examine the hypothesized relationships. Data was collected from Singaporean women between 40 to 69 years of age. The data was analyzed using hierarchical regression. Results: Amongst all predictors tested, we found that Perceived Severity influences protection motivation (Beta=.346, p=.033), whereas Perceived Vulnerability has little effect on protection motivation (Beta= .075, p=. 355). There is also a significant relationship between Self-Efficacy and protection intention (Beta= .373, p<.001). However, contrary to expectations, neither Response Cost (Beta=.136, p=.101) nor Physical Cost (Beta=-.051, p=-.036) was related to protection intention. Conclusions: Our findings indicate that coping appraisal variables are more significantly associated with protection motivation than threat appraisal variables. In particular, self-efficacy was found to be the strongest predictor of breast cancer screening intentions, whereas response cost and physical cost were found to have little effect. This implies that breast cancer screening motivators should communicate the ease of undergoing the procedure and other confidence building messages. Implications for health education and policy are discussed.
Involvement of phospholipid end groups of group C Neisseria meningitidis and Haemophilus influenzae type b polysaccharides in association with isolated outer membranes and in immunoassays

There are several bacterial polysaccharides (PSs) which contain a terminal lipid moiety. It has been postulated that these terminal lipid moieties anchor the PSs to the outer membrane of the bacteria. Our studies have shown that incubation of native PS from group C Neisseria meningitidis or Haemophilus influenzae type b with isolated outer membrane vesicles results in association of a portion of the PS with the vesicles. Removal of the terminal lipid from the PS by treatment with phospholipase A2 or phospholipase D eliminates this association. In other studies, it was shown that delipidated PSs are not suitable as solid-phase antigens in a currently used enzyme-linked immunosorbent assay (ELISA). Measurement of antibody units in the reference sera by using delipidated PSs as antigens in an ELISA yielded negligible absorbance compared with native PSs when methylated human serum albumin was used to coat the PSs to the plate. Nevertheless, phospholipase A2 and phospholipase D treatment did not noticeably affect antigenic epitopes, since soluble group C PS without the terminal lipid bound antibody as effectively as the native PS did, as measured by a competitive inhibition assay. Both hydrophobic and electrostatic interactions are important for the binding of group C N. meningitidis PS to the ELISA plate, while charge interactions seem to be sufficient for binding the more negatively charged H. influenzae type b PS.
Cell fusion during yeast mating requires high levels of a-factor mating pheromone

During conjugation, two yeast cells fuse to form a single zygote. Cell fusion requires extensive remodeling of the cell wall, both to form a seal between the two cells and to remove the intervening material. The two plasma membranes then fuse to produce a continuous cytoplasm. We report the characterization of two cell fusion defective (Fus-) mutants, fus5 and fus8, isolated previously in our laboratory. Fluorescence and electron microscopy demonstrated that the fus5 and fus8 mutant zygotes were defective for cell wall remodeling/removal but not plasma membrane fusion. Strikingly, fus5 and fus8 were a specific; both mutations caused the mutant phenotype when present in the MATa parent but not in the MAT alpha parent. Consistent with an a-specific defect, the fus5 and fus8 mutants produced less a-factor than the isogenic wild-type strain. FUS5 and FUS8 were determined to be allelic to AXL1 and RAM1, respectively, two genes known to be required for biogenesis of a-factor. Several experiments demonstrated that the partial defect in a-factor production resulted in the Fus- phenotype. First, overexpression of a-factor in the fus mutants suppressed the Fus- defect. Second, matings to an MAT alpha partner supersensitive to mating pheromone (sst2 delta) suppressed the Fus- defect in trans. Finally, the gene encoding a-factor, MFA1, was placed under the control of a repressible promoter; reduced levels of wild-type a-factor caused an identical cell fusion defect during mating. We conclude that high levels of pheromone are required as one component of the signal for prezygotes to initiate cell fusion.
Emotion recognition from physiological signals using fusion of wavelet based features

In this paper we propose a new system for human emotion recognition based on multi resolution analysis of physiological signals. In our study we have used four kinds of bio signals EMG, RESP, ECG and SC recorded at the University of Augsburg. Daubechies Symlet, Haar and Morlet wavelet transform were applied to analyze the non-stationary signals. Physiological features was extracted from the most relevant wavelet coefficients and the feature vectors obtained from each signal were combined using multimodal fusion technique to construct one feature vector for each emotion. A support vector machine (SVM) was adopted as a pattern classifier, an improved recognition accuracy of 95% was obtained and it clearly proves the performance of our new wavelet based approach in emotion recognition.
MIMO radar target location accuracy using multiple widely separated antenna arrays

This work investigates the target localization capabilities of a multiple input multiple output (MIMO) radar with multiple widely separated transmit and receive sensor arrays. The corresponding Cramer-Rao lower bound (CRLB) is derived for noncoherent estimation of a target's location. The derived CRLB can be seen as a generalization of the CRLB for a monostatic radar with a single sensor array. It can also be interpreted as a generalization of the CRLB for a MIMO radar with widely separated single-element antennas. Performance of the MIMO radar with widely separated sensor arrays is compared to the MIMO radar with widely separated single-element antennas. The influence of the sensor array length on the target localization performance is analyzed.