Miracle-dz/UniFAR-FTUs huggingface dataset:
One-way shared memory

Standard multicore processors use the shared main memory via the on-chip caches for communication between cores. However, this form of communication has two limitations: (1) it is hardly time-predictable and therefore not a good solution for real-time systems and (2) this single shared memory is a bottleneck in the system. This paper presents a communication architecture for time-predictable multicore systems where core-local memories are distributed on the chip. A network-on-chip constantly copies data from a sender core-local memory to a receiver core-local memory. As this copying is performed in one direction we call this architecture a one-way shared memory. With the use of time-division multiplexing for the memory accesses and the network-on-chip routers we achieve a time-predictable solution where the communication latency and bandwidth can be bounded. An example architecture for a 3×3 core processor and 32-bit wide links and memory ports provides a cumulative bandwidth of 29 bytes per clock cycle. Furthermore, the evaluation shows that this architecture, due to its simplicity, is small compared to other network-on-chip solutions.
Converging Evidence From Electrocorticography and BOLD fMRI for a Sharp Functional Boundary in Superior Temporal Gyrus Related to Multisensory Speech Processing

Although humans can understand speech using the auditory modality alone, in noisy environments visual speech information from the talker’s mouth can rescue otherwise unintelligible auditory speech. To investigate the neural substrates of multisensory speech perception, we recorded neural activity from the human superior temporal gyrus using two very different techniques: either directly, using surface electrodes implanted in five participants with epilepsy (electrocorticography, ECOG), or indirectly, using blood oxygen level dependent functional magnetic resonance imaging (BOLD fMRI) in six healthy control fMRI participants. Both ECOG and fMRI participants viewed the same clear and noisy audiovisual speech stimuli and performed the same speech recognition task. Both techniques demonstrated a sharp functional boundary in the STG, which corresponded to an anatomical boundary defined by the posterior edge of Heschl’s gyrus. On the anterior side of the boundary, cortex responded more strongly to clear audiovisual speech than to noisy audiovisual speech, suggesting that anterior STG is primarily involved in processing unisensory auditory speech. On the posterior side of the boundary, cortex preferred noisy audiovisual speech or showed no preference and showed robust responses to auditory-only and visual-only speech, suggesting that posterior STG is specialized for processing multisensory audiovisual speech. For both ECOG and fMRI, the transition between the functionally distinct regions happened within 10 mm of anterior-to-posterior distance along the STG. We relate this boundary to the multisensory neural code underlying speech perception and propose that it represents an important functional division within the human speech perception network.
Evaluating User Satisfaction with Typography Designs via Mining Touch Interaction Data in Mobile Reading

Previous work has demonstrated that typography design has a great influence on users' reading experience. However, current typography design guidelines are mainly for general purpose, while the individual needs are nearly ignored. To achieve personalized typography designs, an important and necessary step is accurately evaluating user satisfaction with the typography designs. Current evaluation approaches, e.g., asking for users' opinions directly, however, interrupt the reading and affect users' judgments. In this paper, we propose a novel method to address this challenge by mining users' implicit feedbacks, e.g., touch interaction data. We conduct two mobile reading studies in Chinese to collect the touch interaction data from 91 participants. We propose various features based on our three hypotheses to capture meaningful patterns in the touch behaviors. The experiment results show the effectiveness of our evaluation models with higher accuracy on comparing with the baseline under three text difficulty levels, respectively.
Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition

Abstract Extracellular vesicles (EVs) have been shown to play an important role in intercellular communication as carriers of DNA, RNA and proteins. While the intercellular transfer of miRNA through EVs has been extensively studied, the stability of extracellular miRNA (ex-miRNA) once engulfed by a recipient cell remains to be determined. Here, we identify the ex-miRNA-directed phenotype to be transient due to the rapid decay of ex-miRNA. We demonstrate that the ex-miR-223-3p transferred from polymorphonuclear leukocytes to cancer cells were functional, as demonstrated by the decreased expression of its target FOXO1 and the occurrence of epithelial-mesenchymal transition reprogramming. We showed that the engulfed ex-miRNA, unlike endogenous miRNA, was unstable, enabling dynamic regulation and a return to a non-invasive phenotype within 8 h. This transient phenotype could be modulated by targeting XRN1/PACMAN exonuclease. Indeed, its silencing was associated with slower decay of ex-miR-223-3p and subsequently prolonged the invasive properties. In conclusion, we showed that the ‘steady step’ level of engulfed miRNA and its subsequent activity was dependent on the presence of a donor cell in the surroundings to constantly fuel the recipient cell with ex-miRNAs and of XRN1 exonuclease, which is involved in the decay of these imported miRNA.
An isolated high power small-size interleaved full-bridge PFC rectifier for 400 volt telecom energy distribution systems

In new 400 volt energy distribution systems for telecommunication sites and data centers power density is an influential factor which is commonly desired to be provided such that the systems occupy a small space. On top of that in 400 volt energy distribution systems galvanic isolation is investigated to be inevitable. In this paper a new method is presented that makes it possible to interleave the topology of an isolated low-cost low-size rectifier in which the DC link capacitor of power factor correction stage and DC_DC stage inductor are eliminated and as result it is shown that all the benefits of interleaving such as low current ripple and higher power density are combined with the advantages of the proposed isolated low-cost low-size topology and a brand new method for rectifier design is obtained which excels in power-density, current ripple, and size compared to conventional topologies.
Distance and Attraction: Gravity Models for Geographic Content Production

Volunteered Geographic Information (VGI), such as contributions to OpenStreetMap and geotagged Wikipedia articles, is often assumed to be produced locally. However, recent work has found that peer-produced VGI is frequently contributed by non-locals. We evaluate this approach across hundreds of content types from Wikipedia, OpenStreetMap, and eBird, and show that these models can describe more than 90% of "VGI flows" for some content types. Our findings advance geographic HCI theory, suggesting some spatial mechanisms underpinning VGI production. We also discuss design implications that can help (a) human and algorithmic consumers of VGI evaluate the perspectives it contains and (b) address geographic coverage variations in these platforms (e.g. via more effective volunteer recruitment strategies).
Towards a system for integrating heterogeneous health records

Exchanging and sharing medical information between Hospital Information Systems (HIS) is a prevailing problem. The difficulty of this exchange is due to patient mobility and the presence of a large number of HIS in the world. Therefore, medical data are represented in heterogeneous formats that need to be integrated to build interoperate applications. Interoperability, independently of platforms, aims to ensure cooperation, communication and sharing information and services among several applications. To achieve interoperability in the medical field, we create a system for integrating heterogeneous Health Information Systems using the schema matching technique. The matching techniques are solutions to find automatically semantic correspondence between XML schemas in order to allow their integration in the information systems. The objective of our work is to create a new matching tool especially designed for the medical field. For that, we utilize the Metathesaurus in the Unified Medical Language System (UMLS) to perform the results. The evaluation of our tests on real world schemas show that our system offers a high quality of matching results and they are very encouraging.
Numerical study of the cyclic behavior of steel plate shear wall systems (SPSWs) with differently shaped openings

This paper presents the development of finite element (FE) models to simulate the behavior of diagonally stiffened steel plate shear wall systems (SPSWs) with differently shaped openings subjected to a cyclic load. This walling system has the potential to be used for shear elements that resist lateral loads in steel-framed buildings. A number of ½-scale one-story buildings that were un-stiffened, stiffened and stiffened with opening SPSWs are modeled and simulated using the finite element method based on experimental data from previous research. After validating the finite element (FE) models, the effects of infill plate thickness on the cyclic behavior of steel shear walls are investigated. Furthermore, triple diagonal stiffeners are added to the steel infill plates of the SPSWs, and the effects are studied. Moreover, the effects of a number of differently shaped openings applied to the infill plate are studied. The results indicate that the bearing capacity and shear resistance are affected positively by increasing the infill plate thickness and by adding triple diagonal stiffeners. In addition, the cyclic behavior of SPSWs is improved, even with an opening in the SPSWs.
Variational Inference In Pachinko Allocation Machines

The Pachinko Allocation Machine (PAM) is a deep topic model that allows representing rich correlation structures among topics by a directed acyclic graph over topics. Because of the flexibility of the model, however, approximate inference is very difficult. Perhaps for this reason, only a small number of potential PAM architectures have been explored in the literature. In this paper we present an efficient and flexible amortized variational inference method for PAM, using a deep inference network to parameterize the approximate posterior distribution in a manner similar to the variational autoencoder. Our inference method produces more coherent topics than state-of-art inference methods for PAM while being an order of magnitude faster, which allows exploration of a wider range of PAM architectures than have previously been studied.
Food choices and distress in reservation-based American Indians and Alaska Natives with type 2 diabetes

Abstract Objective To examine the association between food choice and distress in a large national sample of American Indians/Alaska Natives (AI/AN) with type 2 diabetes. Design Participants completed a sociodemographic survey, an FFQ and the Kessler-6 Distress Scale. Foods were identified as ‘healthy’ or ‘unhealthy’ using a classification grounded in the health education provided by the programme case managers; healthy and unhealthy food scores were calculated using reported intake frequencies. Pearson’s correlation coefficients for distress and food scores were calculated for all participants and by gender. Multiple linear regression models stratified by gender assessed the association between distress and food scores, controlling for sociodemographics and duration of type 2 diabetes. Setting Rural AI reservations and AN villages. Subjects AI/AN (n 2484) with type 2 diabetes. Results Both males (34·9 %) and females (65·1 %) had higher healthy food scores than unhealthy scores. In bivariate analysis, distress level had a significant negative correlation with healthy food scores among female participants, but the association was not significant among males. Significant positive correlations between distress and unhealthy food scores were found in both genders. In the final multivariate models, healthy food scores were not significantly related to distress; however, unhealthy food scores showed significant positive relationships with distress for both genders (females: β=0·078, P=0·0007; males: β=0·139, P<0·0001). Conclusions Health professionals working with AI/AN diagnosed with type 2 diabetes should offer food choice strategies during difficult times and recognize that males may be more likely than females to select unhealthy foods when distressed.
Reciprocal Phosphorylation and Glycosylation Recognition Motifs Control NCAPP1 Interaction with Pumpkin Phloem Proteins and Their Cell-to-Cell Movement[W]

In plants, cell-to-cell trafficking of non-cell-autonomous proteins (NCAPs) involves protein–protein interactions, and a role for posttranslational modification has been implicated. In this study, proteins contained in pumpkin (Cucurbita maxima cv Big Max) phloem sap were used as a source of NCAPs to further explore the molecular basis for selective NCAP trafficking. Protein overlay assays and coimmunoprecipitation experiments established that phosphorylation and glycosylation, on both Nicotiana tabacum NON-CELL-AUTONOMOUS PATHWAY PROTEIN1 (Nt-NCAPP1) and the phloem NCAPs, are essential for their interaction. Detailed molecular analysis of a representative phloem NCAP, Cm-PP16-1, identified the specific residues on which glycosylation and phosphorylation must occur for effective binding to NCAPP1. Microinjection studies confirmed that posttranslational modification on these residues is essential for cell-to-cell movement of Cm-PP16-1. Lastly, a glutathione S-transferase (GST)–Cm-PP16-1 fusion protein system was employed to test whether the peptide region spanning these residues was required for cell-to-cell movement. These studies established that a 36–amino acid peptide was sufficient to impart cell-to-cell movement capacity to GST, a normally cell-autonomous protein. These findings are consistent with the hypothesis that a phosphorylation-glycosylation recognition motif functions to control the binding of a specific subset of phloem NCAPs to NCAPP1 and their subsequent transport through plasmodesmata.
VR-OOM: Virtual Reality On-rOad driving siMulation

Researchers and designers of in-vehicle interactions and interfaces currently have to choose between performing evaluation and human factors experiments in laboratory driving simulators or on-road experiments. To enjoy the benefit of customizable course design in controlled experiments with the immediacy and rich sensations of on-road driving, we have developed a new method and tools to enable VR driving simulation in a vehicle as it travels on a road. In this paper, we describe how the cost-effective and flexible implementation of this platform allows for rapid prototyping. A preliminary pilot test (N = 6), centered on an autonomous driving scenario, yields promising results, illustrating proof of concept and indicating that a basic implementation of the system can invoke genuine responses from test participants.
Incidence of and Risk Factors for Venous Thromboembolism After Foot and Ankle Surgery

Background: Venous thromboembolism (VTE) is a rare but potentially lethal complication after orthopaedic foot and ankle surgery. The true incidence of VTE after orthopaedic foot and ankle surgery stratified by specific procedure has yet to be examined. The purpose of this study is to report the incidence of and identify risk factors for VTE in a large sample of patients receiving orthopaedic foot and ankle surgery. Methods: In this study, we retrospectively analyzed data from the National Surgical Quality Improvement Program 2006 to 2015 data files. The incidence of VTE was calculated for 30 specific orthopaedic foot and ankle surgeries and for 4 broad types of foot and ankle surgery. Demographic, comorbidity, and complication variables were analyzed to determine associations with development of VTE. Results: The overall incidence of VTE in our sample was 0.6%. The types of procedures with the highest frequency of VTE were ankle fractures (105/15 302 cases, 0.7%), foot pathologies (28/5466, 0.6%), and arthroscopy (2/398, 0.5%). Female gender, increasing age, obesity, inpatient status, and nonelective surgery were all significantly associated with VTE. Conclusion: Although VTE after orthopaedic foot and ankle surgery is a rare occurrence, several high-risk groups and procedures may be especially indicated for chemical thromboprophylaxis. Levels of Evidence: Level III: Retrospective, comparative study
Point-and-Shake: Selecting from Levitating Object Displays

Acoustic levitation enables a radical new type of human-computer interface composed of small levitating objects. For the first time, we investigate the selection of such objects, an important part of interaction with a levitating object display. We present Point-and-Shake, a mid-air pointing interaction for selecting levitating objects, with feedback given through object movement. We describe the implementation of this technique and present two user studies that evaluate it. The first study found that users could accurately (96%) and quickly (4.1s) select objects by pointing at them. The second study found that users were able to accurately (95%) and quickly (3s) select occluded objects. These results show that Point-and-Shake is an effective way of initiating interaction with levitating object displays.
The Selective Antagonism of Adenosine A2B Receptors Reduces the Synaptic Failure and Neuronal Death Induced by Oxygen and Glucose Deprivation in Rat CA1 Hippocampus in Vitro

Ischemia is a multifactorial pathology characterized by different events evolving in time. Immediately after the ischemic insult, primary brain damage is due to the massive increase of extracellular glutamate. Adenosine in the brain increases dramatically during ischemia in concentrations able to stimulate all its receptors, A1, A2A, A2B, and A3. Although adenosine exerts clear neuroprotective effects through A1 receptors during ischemia, the use of selective A1 receptor agonists is hampered by their undesirable peripheral side effects. So far, no evidence is available on the involvement of adenosine A2B receptors in cerebral ischemia. This study explored the role of adenosine A2B receptors on synaptic and cellular responses during oxygen and glucose deprivation (OGD) in the CA1 region of rat hippocampus in vitro. We conducted extracellular recordings of CA1 field excitatory post-synaptic potentials (fEPSPs); the extent of damage on neurons and glia was assessed by immunohistochemistry. Seven min OGD induced anoxic depolarization (AD) in all hippocampal slices tested and completely abolished fEPSPs that did not recover after return to normoxic condition. Seven minutes OGD was applied in the presence of the selective adenosine A2B receptor antagonists MRS1754 (500 nM) or PSB603 (50 nM), separately administered 15 min before, during and 5 min after OGD. Both antagonists were able to prevent or delay the appearance of AD and to modify synaptic responses after OGD, allowing significant recovery of neurotransmission. Adenosine A2B receptor antagonism also counteracted the reduction of neuronal density in CA1 stratum pyramidale, decreased apoptosis at least up to 3 h after the end of OGD, and maintained activated mTOR levels similar to those of controls, thus sparing neurons from the degenerative effects caused by the simil-ischemic conditions. Astrocytes significantly proliferated in CA1 stratum radiatum already 3 h after the end of OGD, possibly due to increased glutamate release. A2Breceptor antagonism significantly prevented astrocyte modifications. Both A2B receptor antagonists did not protect CA1 neurons from the neurodegeneration induced by glutamate application, indicating that the antagonistic effect is upstream of glutamate release. The selective antagonists of the adenosine A2B receptor subtype may thus represent a new class of neuroprotective drugs in ischemia.
Adolescents’ Help-Seeking Behavior and Intentions Following Adolescent Dating Violence: A Systematic Review

The review aimed to systematically identify and summarize empirical work examining adolescent victims’ help-seeking behaviors and intentions in relation to their own experience of adolescent dating violence (ADV) and to critically evaluate the literature. Three main objectives were addressed: identify factors associated with help seeking, identify help-seeking source (who adolescents disclose to), and explore the barriers and facilitators for help seeking. Results were separated into actual help seeking and help-seeking intentions. A systematic search was conducted via an electronic search on February 10, 2017. Studies were identified by systematically searching the following electronic databases: Amed, BNI, CINAHL, EMBASE, Health Business Elite, HMIC, Medline, PsychINFO, and PubMed. Nineteen studies were included in the review. Adolescents were more likely to go to informal sources of support, with friends being the most commonly reported source. The majority of studies found females were more likely than males to seek help; however, inconsistencies in gender differences emerged. The variation in measurement and definition of ADV and help seeking included in this review impacts on its conclusions. Adolescents identify a number of barriers to help seeking for ADV. Emotional factors were identified as important barriers to seeking help; however, very little research in this review explored this area. Further research is required on age and cultural differences, use of the Internet, and preference for different sources for different types of abuse. There is a need for a greater focus on help seeking to ensure government campaigns are appropriately meeting the needs of young people experiencing ADV.
Multi-standard radio for 2G to 5G

Todays generation is highly dependent on mobile communication. To satisfy the quest of high speed, better connectivity, better performance etc; mobile communication has evolved from 1G to 4G. As with 4G, the concept of Internet of things has come into the picture. For Internet of Things, millions of devices needed to be connected simultaneously and hence 4G bandwidth standalone will not be able to do so. Hence up gradation to 5G is highly desirable. Not only that, 5G will also be able to provide fastest speed, lower energy consumption, low latency etc. With an objective of launching 5G in Tokyo Olympics 2020, research on 5G has already started. 5G will be demoed in winter Olympics 2018. As mobile communication is upgrading to 5G, transmitters of base transceiver stations are compelled to transition into a new combined technology known as Multi-Standard Radio. In this paper, Multi-Standard Radio signal generation is shown which will combine FBMC, LTE, WCDMA, GSM and EDGE at different input sample rates and carrier frequencies. System Vue 2016.08 is used as system design platform and simulation platform.