Miracle-dz/UniFAR-FTUs huggingface dataset:
th CIRP Conference on MANUFACTURING SYSTEMS-CIRP CMS 2015 On the use of Multi-Depth-Camera based Motion Tracking Systems in Production Planning Environments

In order to keep up with changing market demands like highly individualized products, automotive OEMs are facing these new requirements with mass-customization and more efficient digital methods. With the ongoing virtualization of production planning and verification, new technologies are necessary to facilitate interaction with virtual environments for planning experts. While marker-based motion capture systems have been used for tracking of worker movements and interaction with those digital models until now, with the advent of markerless tracking technologies like the Kinect depth cameras, those solutions attract more interest because of their reduced cost, ease of use and the absence of cumbersome suits and markers. However, when using depth cameras, which have been primarily designed as short-range gaming devices, different issues arise when dealing with large-scale setups common in shop floor and production planning environments. Similar to traditional motion capture systems, it is necessary to deal with occlusions, camera registration and calibration and fusion of multi-depth-camera data to obtain a sufficiently large and robust tracking space. For this purpose, we propose such a novel multi-depth-camera approach, which is able to register itself only by observing the worker’s trajectory. It is then able to reliably track the worker movements across a large space and also optimize the skeletal tracking. Through its distributed and scalable approach, the multi-depth camera system can be set up flexible for versatile tracking scenarios in practical production planning use. Based on sensor hardware specific quality criteria, it is able to fuse incoming tracking data and to provide a coherent view of the tracking space even in difficult tracking situations. © 2015 The Authors. Published by Elsevier B.V. Peer-review under responsibility of the Scientific Committee of 48th CIRP Conference on MANUFACTURING SYSTEMS CIRP CMS 2015.
Immediate Translation of Formin DIAPH1 mRNA after Its Exiting the Nucleus Is Required for Its Perinuclear Localization in Fibroblasts

DIAPH1 is a formin protein which promotes actin polymerization, stabilizes microtubules and consequently is involved in cytoskeleton dynamics, cell migration and differentiation. In contrast to the relatively well-understood signaling cascades that regulate DIAPH1 activity, its spatial regulation of biogenesis is not understood. A recent report showed that synthesis of DIAPH1 is confined in the perinuclear ER compartment through translation-dependent mRNA targeting. However, the underlying mechanism of DIAPH1 local synthesis is yet to be elucidated. Here, we provide evidence to demonstrate that the 5′-cap-mediated immediate translation of DIAPH1 mRNA upon exiting nucleus is required for localizing the mRNA in the perinuclear ER compartment. This is supported by data: 1) Delayed translation of DIAPH1 mRNA resulted in loss of perinuclear localization of the mRNA; 2) Once delocalized, DIAPH1 mRNA could not be retargeted to the perinuclear region; and 3) The translation of DIAPH1 mRNA is 5′-cap dependent. These results provide new insights into the novel mechanism of DIAPH1 local synthesis. In addition, these findings have led to the development of new approaches for manipulating DIAPH1 mRNA localization and local protein synthesis in cells for functional studies. Furthermore, a correlation of DIAPH1 mRNA and DIAPH1 protein localization has been demonstrated using a new method to quantify the intracellular distribution of protein.
Construction K-Dominating Set with Multiple Relaying Technique in Wireless Mobile Ad Hoc Networks

The (k, r)-dominating set problem, (k, r)-DS, is defined as the problem of selecting a minimum cardinality vertex set D (dominating nodes, also referred as cluster-heads) of a graph G=(V, E), such that every vertex u not in D is in r hops from at least k (multiple domination parameter) vertices in D. In mobile ad hoc networks (MANETs), computing dominating set should be distributed, because the topology may change frequently. In this paper, we present a distributed clustering algorithm based on MPR technique, named MPR-KD, to addressing redundancy of dominating nodes in 1-hop for MANETs. 1-CDS is still supported in MPR-KD and extensive simulations are conducted to compare this algorithm with another distributed algorithm DKR. Simulation results show that the new algorithm outperforms DKR in terms of number of dominating nodes, both in dense and sparse networks.
Complete Sequences of Four Plasmids of Lactococcus lactis subsp. cremoris SK11 Reveal Extensive Adaptation to the Dairy Environment

ABSTRACT Lactococcus lactis strains are known to carry plasmids encoding industrially important traits. L. lactis subsp. cremoris SK11 is widely used by the dairy industry in cheese making. Its complete plasmid complement was sequenced and found to contain the plasmids pSK11A (10,372 bp), pSK11B (13,332 bp), pSK11L (47,165 bp), and pSK11P (75,814 bp). Six highly homologous repB-containing replicons were found, all belonging to the family of lactococcal theta-type replicons. Twenty-three complete insertion sequence elements segment the plasmids into numerous modules, many of which can be identified as functional units or containing functionally related genes. Plasmid-encoded functions previously known to reside on L. lactis SK11 plasmids were now mapped in detail, e.g., lactose utilization (lacR-lacABCDFEGX), the proteolytic system (prtM-prtP, pepO, pepF), and the oligopeptide permease system (oppDFBCA). Newly identified plasmid-encoded functions could facilitate the uptake of various cations, while the pabA and pabB genes could be essential for folate biosynthesis. A competitive advantage could be obtained by using the putative flavin adenine dinucleotide-dependent d-lactate dehydrogenase and oxalate:formate antiporter for enhanced ATP synthesis, while the activity of the predicted α-acetolactate decarboxylase may contribute to the formation of an additional electron sink. Various stress response proteins are plasmid encoded, which could enhance strain robustness. A substantial number of these “adaptation” genes have not been described before on L. lactis plasmids. Moreover, several genes were identified for the first time in L. lactis, possibly reflecting horizontal gene transfer.
Flip chip joining on FR-4 substrate using ACFs

Anisotropic conductive adhesive films (ACF) were used to attach daisy-chained test chips on FR-4 substrates. The feasibility of ACF joining was studied since it is a potential method for fine-pitch bare-die attachment on low-cost organic substrates. Four types of test chips were used, each having a pitch of different size. One of the chips had an area array structure, one had a staggered structure, while the others had a peripheral structure. The reliability of the flip chip joints was evaluated by subjecting the test chips to a temperature cycling test and to a preceding reflow aging test. The joints were studied by electrical measurements and scanning electron microscope. The alignment of the chips was confirmed with an x-ray microscope. Low resistance values were obtained in the flip chip joining process. However, it is evident that coplanarity of the substrate and the chip is important for the bonding quality. During the reflow aging test and the reliability tests some of the tested samples seemed to fail due to stresses that had induced during the bonding process. The reason for the failures was a too high bonding pressure. By decreasing the bonding pressure, reliability of these test chip types was improved.
Working for a better future: Social mobility beliefs and expectations of Filipino migrant workers in Macau

Objective Household theory of labour migration assumes that the decision to work in another country is a family's strategy to improve prospects of socio‐economic mobility. We inquired into the social cognitive processes associated with this goal by applying model of pathways to socio‐economic mobility, but extending the types of causal conceptions related to social mobility that are considered important in the Philippine context. Method We surveyed 246 Filipino migrant workers in Macau, who answered questions about perceptions of the socio‐economic status of their family (before they worked abroad, presently, and 10 years after), socio‐economic mobility causal conceptions (merit, luck, faith in God, social networks), and goal‐attainment strategies (goal engagement, goal disengagement). Results Migrant workers expect improved socio‐economic status of their families compared to before, and they expect further improvement after 10 years. They endorsed faith in God and meritocracy as important causal factors to mobility. Path analysis indicated two pathways to socio‐economic mobility expectations: (1) engagement‐promoting pathway—involving faith in God and meritocracy as causal conceptions related to goal engagement, and higher socio‐economic mobility expectations and (2) disengagement‐promoting pathway—involving luck as causal conception related to goal disengagement, and lower socio‐economic mobility expectations. Conclusion Although working abroad is fraught with uncertainties, Filipino migrant workers aspire for upward socio‐economic mobility for their families, which they seek to attain by working hard and persistence, which in turn relate to causal conceptions of mobility that involve controllable factors.
LC–MS/MS Quantitation of Esophagus Disease Blood Serum Glycoproteins by Enrichment with Hydrazide Chemistry and Lectin Affinity Chromatography

Changes in glycosylation have been shown to have a profound correlation with development/malignancy in many cancer types. Currently, two major enrichment techniques have been widely applied in glycoproteomics, namely, lectin affinity chromatography (LAC)-based and hydrazide chemistry (HC)-based enrichments. Here we report the LC–MS/MS quantitative analyses of human blood serum glycoproteins and glycopeptides associated with esophageal diseases by LAC- and HC-based enrichment. The separate and complementary qualitative and quantitative data analyses of protein glycosylation were performed using both enrichment techniques. Chemometric and statistical evaluations, PCA plots, or ANOVA test, respectively, were employed to determine and confirm candidate cancer-associated glycoprotein/glycopeptide biomarkers. Out of 139, 59 common glycoproteins (42% overlap) were observed in both enrichment techniques. This overlap is very similar to previously published studies. The quantitation and evaluation of significantly changed glycoproteins/glycopeptides are complementary between LAC and HC enrichments. LC–ESI–MS/MS analyses indicated that 7 glycoproteins enriched by LAC and 11 glycoproteins enriched by HC showed significantly different abundances between disease-free and disease cohorts. Multiple reaction monitoring quantitation resulted in 13 glycopeptides by LAC enrichment and 10 glycosylation sites by HC enrichment to be statistically different among disease cohorts.
Proadrenomedullin NH2-Terminal 20 Peptide Is a Potent Angiogenic Factor, and Its Inhibition Results in Reduction of Tumor Growth

We have found through ex vivo and in vivo angiogenesis models that the adrenomedullin gene-related peptide, proadrenomedullin NH2-terminal 20 peptide (PAMP), exhibits a potent angiogenic potential at femtomolar concentrations, whereas classic angiogenic factors such as vascular endothelial growth factor and adrenomedullin mediate a comparable effect at nanomolar concentrations. We found that human microvascular endothelial cells express PAMP receptors and respond to exogenous addition of PAMP by increasing migration and cord formation. Exposure of endothelial cells to PAMP increases gene expression of other angiogenic factors such as adrenomedullin, vascular endothelial growth factor, basic fibroblast growth factor, and platelet-derived growth factor C. In addition, the peptide fragment PAMP(12-20) inhibits tumor cell–induced angiogenesis in vivo and reduces tumor growth in xenograft models. Together, our data demonstrate PAMP to be an extremely potent angiogenic factor and implicate this peptide as an attractive molecular target for angiogenesis-based antitumor therapy.
Developing a Testlet Model for Mathematics at Elementary Level

The purpose of this study was to develop a Mathematics test instrument testlet model for a classroom assessment at elementary school. Testlet Model is a group of multiple choice question acquiring similar information with different grade of responses model. This research was conducted in East Lombok, Indonesia. The design used was research development model. The study involved 17 doctoral students as peer reviewers, 19 teachers as testlet preparation workshop participants and 711 students for testing the testlet mathematical test instrument. Data collection techniques used were documentation techniques, interviews and questionnaires. Expert validation results were analyzed using Content Validity Index (CVI). Analysis of the trial results was using items response theory with a graded response model of two logistic parameters. Independent sample t test was used for comparison of tests. The research developed a Mathematics test instrument testlet model successfully for a classroom assessment consisting of the testlet model test design, grading guide, test instrument preparation guide and mathematics test instrument testlet model or an accurate and reliable classroom assessment. The result of the analysis shows that there was different result between assessments using testlet compared to multiple choices scoring, with t value equal to 7.864.
Image restoration and disparity estimation from an uncalibrated multi-layered image

Watching a reflection in a glass window, one can often observe a multi-layered image consisting of a front-surface reflection from the glass and a rear-surface reflection through the glass. That multi-layered image is a composition of dual aspects of the same image, resembling a sound reverberation. As described herein, we propose a method to estimate the original reflection image before the layering. First, we model the multi-layered image generation process; then we derive a restoration filter by assuming that the displacement between the multiple reflection images in the single multi-layered image is known. Second, we propose a method to estimate the original image in conjunction with the displacement estimation. The displacement between the reflection images in a single multi-layered image includes scene depth information. Finally, we demonstrate the effectiveness of our proposed method using both synthetic and real multi-layered images.
World Library and Information Congress: 69th Ifla General Conference and Council Professional Values Revisited: the Case of Croatia

The revival of interest for the ethical issues in the library community is related both to the changes brought about by the application of new technologies in libraries and the societal changes taking place in the countries in transition. A survey of five ethical codes of national library associations of Bosnia and Herzegovina, Croatia, Macedonia, Slovenia, Serbia and Montenegro was made and professional values emphasised in the codes were compared. In order to find out whether the professional values proclaimed in the codes agree with the personal attitudes of librarians an investigation of the professional values of Croatian librarians was conducted. The preliminary results point to the conclusion that Croatian librarians share at least some of the values with their colleagues in other parts of the world, while some of the values have not yet been fully recognised. Introduction The revival of interest for the ethical issues can certainly be related to the changes in the library environment brought about by new technologies, whose introduction has deeply affected and transformed the library work. Although there is no agreement on whether or not new technologies have introduced new ethical issues, (1) ethics seems to have become an interesting topic for the information profession. Even if it is true that the debate on ethics started among computing and philosophy professionals in the early 1990s and that librarians followed later, (2) the library profession current interest in ethics is easily confirmed by only a superficial glance in a bibliographic database, such as Emerald, that reveals 25 articles on library ethics published between 1996 and 2002.
Precariousness Profile and Career Adaptability as Determinants of Job Insecurity: A Three-Wave Study

The present study compares the mean levels and growth in job insecurity across employees’ precariousness profiles as defined by a combination of perceived employability and financial difficulties. Drawing on the labor market precariousness and workplace stress literature, we hypothesized that employees with the most precarious profile would report elevated levels of job insecurity followed by a growth trend. Moreover, career adaptability was expected to act as a resource for counteracting job insecurity. The study was based on three waves of a longitudinal “Professional Paths” survey (National Centre of Competence in Research LIVES) conducted in Switzerland. The data of 799 professionally active adults were analyzed using latent growth modeling. In line with our hypothesis, the findings showed the highest levels of job insecurity and the most pronounced growth trend among employees with the precarious profile. Interestingly, different career adaptability facets played differing roles in predicting job insecurity, potentially revealing some of its under-researched aspects.
Comparison and anti-concentration bounds for maxima of Gaussian random vectors

Slepian and Sudakov–Fernique type inequalities, which compare expectations of maxima of Gaussian random vectors under certain restrictions on the covariance matrices, play an important role in probability theory, especially in empirical process and extreme value theories. Here we give explicit comparisons of expectations of smooth functions and distribution functions of maxima of Gaussian random vectors without any restriction on the covariance matrices. We also establish an anti-concentration inequality for the maximum of a Gaussian random vector, which derives a useful upper bound on the Lévy concentration function for the Gaussian maximum. The bound is dimension-free and applies to vectors with arbitrary covariance matrices. This anti-concentration inequality plays a crucial role in establishing bounds on the Kolmogorov distance between maxima of Gaussian random vectors. These results have immediate applications in mathematical statistics. As an example of application, we establish a conditional multiplier central limit theorem for maxima of sums of independent random vectors where the dimension of the vectors is possibly much larger than the sample size.
Effects of Temporary Functional Deafferentation on the Brain, Sensation, and Behavior of Stroke Patients

Following stroke, many patients suffer from chronic motor impairment and reduced somatosensation in the stroke-affected body parts. Recent experimental studies suggest that temporary functional deafferentation (TFD) of parts of the stroke-affected upper limb or of the less-affected contralateral limb might improve the sensorimotor capacity of the stroke-affected hand. The present study sought evidence of cortical reorganization and related sensory and motor improvements following pharmacologically induced TFD of the stroke-affected forearm. Examination was performed during 2 d of Constraint-Induced Movement Therapy. Thirty-six human patients were deafferented on the stroke-affected forearm by an anesthetic cream (containing lidocaine and prilocaine) on one of the 2 d, and a placebo cream was applied on the other. The order of TFD and placebo treatment was counterbalanced across patients. Somatosensory and motor performance were assessed using a Grating orienting task and a Shape-sorter-drum task, and with somatosensory-evoked magnetic fields. Evoked magnetic fields showed significant pre- to postevaluation magnitude increases in response to tactile stimulation of the thumb of the stroke-affected hand during TFD but not following placebo treatment. We also observed a rapid extension of the distance between cortical representations of the stroke-affected thumb and little finger following TFD but not following placebo treatment. Moreover, somatosensory and motor performance of the stroke-affected hand was significantly enhanced during TFD but not during placebo treatment. Thus, pharmacologically induced TFD of a stroke-affected forearm might improve the somatosensory and motor functions of the stroke-affected upper limb, accompanied by cortical plasticity.
Manifold learning with local geometry preserving and global affine transformation

This paper proposes a new approach to learn the low dimensional manifold from high dimensional data space. The proposed approach deals with two problems in the previous algorithms. The first problem is local manifold distortion caused by the cost averaging of the global cost optimization during the manifold learning. The second problem results from the unit variance constraint generally used in those spectral embedding methods where global metric information is lost. The formulation of the proposed method is described in details. Experiments on both low dimensional data and real image data are performed to illustrate the theory.
A Rich Probabilistic Model to Predict Yeast Gene Function

Prediction of gene function is an important problem in the post-genome era. Traditionally, functions of unknown genes are inferred from two types of methods: one using the “guilt-byassociation” principle (e.g. [1]), and the other using features of the gene of interest (e.g. [2]). Both types of methods have shown certain success in the task. Here we aim to combine the two principles using one rich probabilistic model.
Methods for Eliciting e-Research User Requirements

e-Research is a relatively new and expanding means of undertaking multi-disciplinary on-line research. As such, the needs and requirements of the e-Research community are not yet fully understood and it is evident that it needs further investigation and study. This paper aims to provide basic guidance on the research methods that will be useful in order to gather information from the users of multi-disciplinary e-Research-based projects. The paper discusses quantitative and qualitative research methods with examples that have been drawn from social and computer science. We show that there are many ways of gaining information from users, but when used appropriately qualitative methods give more depth of information, whereas quantitative methods are scalable to the whole community.
Comprendre le harcèlement pour mieux le prévenir

Le harcelement, ou bullying, est une forme insidieuse de violence qui s’inscrit dans l’intimite des relations sociales. Il est susceptible d’emerger dans tous les contextes sociaux a tout âge et quels que soient les niveaux culturels des acteurs. Dans cet article les grands themes de recherches associes a la question du harcelement sont presentes, dont la plupart font l’objet d’un article specifique dans ce numero thematique. Il s’agit de la question du developpement de l’agression et de la socialisation chez l’enfant, de la specificite des situations de harcelement scolaire, des formes que peuvent prendre le harcelement, en particulier le cyberharcelement, des caracteristiques de ses acteurs, en particulier les agresseurs et les temoins, et enfin d’un programme de prevention.