Miracle-dz/UniFAR-FTUs huggingface dataset:
WR1.5 Silicon Micromachined Waveguide Components and Active Circuit Integration Methodology

This paper describes the development of silicon micromachined waveguide structures operating in the WR1.5 waveguide band (500-750 GHz). Average waveguide loss of 0.15 dB/mm was measured at 600 GHz. Capabilities of the proposed approach have been shown with the development of a 570-GHz three-pole waveguide bandpass filter that has a 0.9-dB passband loss and a Y-junction coupler operating at 670 GHz. These components have been tested using a novel on-wafer testing method for rapid characterization throughput. A batch process approach for integration of solid-state devices and micromachined waveguide components has also been developed. Further development of this technology will lead to the next generation of terahertz-frequency wafer-level packaging of active circuits.
Loupe - An Online Tool for Inspecting Datasets in the Linked Data Cloud

The Linked Data initiative continues to grow making more datasets available; however, discovering the type of data contained in a dataset, its structure, and the vocabularies used still remains a challenge hindering the querying and reuse. VoID descriptions provide a starting point but a more detailed analysis is required to unveil the implicit vocabulary usage such as common data patterns. Such analysis helps the selection of datasets, the formulation of effective queries, or the identification of quality issues. Loupe is an online tool for inspecting datasets by looking at both implicit data patterns as well as explicit vocabulary definitions in data. This demo paper presents the dataset inspection capabilities of Loupe.
A real-time fluorescence polarization activity assay to screen for inhibitors of bacterial ribonuclease P

Ribonuclease P (RNase P) is an essential endonuclease that catalyzes the 5′ end maturation of precursor tRNA (pre-tRNA). Bacterial RNase P is an attractive potential antibacterial target because it is essential for cell survival and has a distinct subunit composition compared to the eukaryal counterparts. To accelerate both structure-function studies and discovery of inhibitors of RNase P, we developed the first real-time RNase P activity assay using fluorescence polarization/anisotropy (FP/FA) with a 5′ end fluorescein-labeled pre-tRNAAsp substrate. This FP/FA assay also detects binding of small molecules to pre-tRNA. Neomycin B and kanamycin B bind to pre-tRNAAsp with a Kd value that is comparable to their IC50 value for inhibition of RNase P, suggesting that binding of these antibiotics to the pre-tRNA substrate contributes to the inhibitory activity. This assay was optimized for high-throughput screening (HTS) to identify specific inhibitors of RNase P from a 2880 compound library. A natural product derivative, iriginol hexaacetate, was identified as a new inhibitor of Bacillus subtilis RNase P. The FP/FA methodology and inhibitors reported here will further our understanding of RNase P molecular recognition and facilitate discovery of antibacterial compounds that target RNase P.
Melodic Cue Abstraction , Similarity , and Category Formation : A Formal Model

347 Address correspondence to Emilios Cambouropoulos, Austrian Research Institute for Artificial Intelligence, Schottengasse 3, A-1010, Vienna, Austria. (e-mail: emilios@ai.univie.ac.at) ISSN: 0730-7829. Send requests for permission to reprint to Rights and Permissions, University of California Press, 2000 Center St., Ste. 303, Berkeley, CA 94704-1223. Melodic Cue Abstraction, Similarity, and Category Formation: A Formal Model
Distilling command and control network intrusions from network flow metadata using temporal PageRank

Malicious network intrusions which exfiltrate data from computer networks are extremely damaging for organisations and governments worldwide. Combating these network intrusions and large-scale cyber-attacks requires mining and analysis of large volumes of computer network data. We present a statistical filtering and temporal PageRank technique that improves the probability of discovering network intrusions. The technique filters out benign network data such that the data remaining is more pertinent and likely to contain malicious command and control (C2) traffic. We then propose a novel application of Google's PageRank algorithm by incorporating temporal analysis and evaluating a time-series of page rankings for identifying C2 like traffic. Two case studies using data collected at the gateway of an enterprise network and at the Internet backbone are presented to support our technique.
Novel active locomotive capsule endoscope with micro-hydraulic pump for drug delivery function

This paper presents a novel mechanism and design of capsule endoscope in order to perform an active locomotive capsule endoscope (ALICE) robot integrated with micro-hydraulic pump for drug delivery function. The proposed locomotive capsule endoscope can actively move and investigate in gastrointestinal tract, powered externally by an electro-magnetic actuation (EMA) system. To perform a drug pumping function, the rotating frequency of the active hydraulic pump can be adjusted by the EMA system. The novel capsule endoscope with the micro-hydraulic pump is focused on target drug delivery function. The capsule endoscope is able to target suspicious region and release controllable amount of drug. Through preliminary tests of the locomotive capsule endoscope with the micro-pump, the feasibility of the locomotion and the drug releasing of the novel capsule endoscope will be presented. The micro-hydraulic pump for a drug delivery function will be a potential component for a future capsule endoscope with active maneuverability, diagnostic and therapeutic functions.
Genetic and molecular alterations in pancreatic cancer: Implications for personalized medicine

Recent advances in human genomics and biotechnologies have profound impacts on medical research and clinical practice. Individual genomic information, including DNA sequences and gene expression profiles, can be used for prediction, prevention, diagnosis, and treatment for many complex diseases. Personalized medicine attempts to tailor medical care to individual patients by incorporating their genomic information. In a case of pancreatic cancer, the fourth leading cause of cancer death in the United States, alteration in many genes as well as molecular profiles in blood, pancreas tissue, and pancreas juice has recently been discovered to be closely associated with tumorigenesis or prognosis of the cancer. This review aims to summarize recent advances of important genes, proteins, and microRNAs that play a critical role in the pathogenesis of pancreatic cancer, and to provide implications for personalized medicine in pancreatic cancer.
Security Challenges and Approaches in Online Social Networks: A Survey

Summary Social Networks (SN) Sites are becoming very popular and the number of users is increasing rapidly. However, with that increase there is also an increase in the security threats which affect the users’ privacy, identity and confidentiality. Different research groups highlighted the security threats in SN and attempted to offer some solutions to these issues. In this paper we survey several examples of this research and highlight the approaches. All the models we surveyed were focusing on protecting users’ information yet they failed to cover other important issues. For example, none of the mechanisms provided the users with control over what others can reveal about them; and encryption of images is still not achieved properly. Generally having higher security measures will affect the system’s performance in terms of speed and response time. However, this trade-off was not discussed or addressed in any of the models we surveyed.
Comparing Willingness-to-Pay Estimates from Experimental Auctions with Mailed Surveys Incorporating Cheap Talk

Willingness-to-pay (WTP) results from experimental auctions are compared to those from cheap-talk and conventional surveys for branded beef products in Canada. It is found that while the cheap-talk survey appears to mitigate hypothetical bias compared to the conventional survey, cheap-talk survey WTP remains higher than that in experimental auctions.
2 ANDRÁS STIPSICZ AND VERA VÉRTESI between sutured

Suppose that L is a null–homologous Legendrian knot in the contact 3– manifold (Y, ξ). We determine the connection between the sutured invariant EH(L) = EH(Y − ν(L), ξ|Y −ν(L)) of L and the Legendrian invariant L̂(L) defined in [15]. In particular, we derive a vanishing theorem for L̂(L) in the presence of Giroux torsion in the complement of the knot, and reprove several known properties of the Legendrian invariant from this perspective.
Modelling Derivatives Pricing Mechanisms with Their Generating Functions

In this paper we study dynamic pricing mechanisms of financial derivatives. A typical model of such pricing mechanism is the so-called g--expectation defined by solutions of a backward stochastic differential equation with g as its generating function. Black-Scholes pricing model is a special linear case of this pricing mechanism. We are mainly concerned with two types of pricing mechanisms in an option market: the market pricing mechanism through which the market prices of options are produced, and the ask-bid pricing mechanism operated through the system of market makers. The later one is a typical nonlinear pricing mechanism. Data of prices produced by these two pricing mechanisms are usually quoted in an option market. We introduce a criteria, i.e., the domination condition (A5) in (2.5) to test if a dynamic pricing mechanism under investigation is a g--pricing mechanism. This domination condition was statistically tested using CME data documents. The result of test is significantly positive. We also provide some useful characterizations of a pricing mechanism by its generating function.
ALD aluminum oxide passivated Surface Acoustic Wave sensor for early iofilm detection oung

We present a successful demonstration of a reusable Surface Acoustic Wave (SAW) sensor for bacterial biofilm growth monitoring in an animal serum and bacterial growth media. Bacterial biofilms produce harmful metabolic by-products and are a characteristic of severe infections. Thus, continuous monitoring of bacterial biofilm growth is critical. Here, we report a highly sensitive SAW sensor for biofilm growth monitoring fabricated by depositing zinc oxide (ZnO) piezoelectric thin film by pulsed laser deposition (PLD). To prevent ZnO damage from long term exposure to bacterial growth media or to an animal serum, the ZnO layer of the sensor was effectively protected by aluminum oxide (Al2O3) using atomic layer urface Acoustic Wave
Diversity of Prdm9 Zinc Finger Array in Wild Mice Unravels New Facets of the Evolutionary Turnover of this Coding Minisatellite

In humans and mice, meiotic recombination events cluster into narrow hotspots whose genomic positions are defined by the PRDM9 protein via its DNA binding domain constituted of an array of zinc fingers (ZnFs). High polymorphism and rapid divergence of the Prdm9 gene ZnF domain appear to involve positive selection at DNA-recognition amino-acid positions, but the nature of the underlying evolutionary pressures remains a puzzle. Here we explore the variability of the Prdm9 ZnF array in wild mice, and uncovered a high allelic diversity of both ZnF copy number and identity with the caracterization of 113 alleles. We analyze features of the diversity of ZnF identity which is mostly due to non-synonymous changes at codons −1, 3 and 6 of each ZnF, corresponding to amino-acids involved in DNA binding. Using methods adapted to the minisatellite structure of the ZnF array, we infer a phylogenetic tree of these alleles. We find the sister species Mus spicilegus and M. macedonicus as well as the three house mouse (Mus musculus) subspecies to be polyphyletic. However some sublineages have expanded independently in Mus musculus musculus and M. m. domesticus, the latter further showing phylogeographic substructure. Compared to random genomic regions and non-coding minisatellites, none of these patterns appears exceptional. In silico prediction of DNA binding sites for each allele, overlap of their alignments to the genome and relative coverage of the different families of interspersed repeated elements suggest a large diversity between PRDM9 variants with a potential for highly divergent distributions of recombination events in the genome with little correlation to evolutionary distance. By compiling PRDM9 ZnF protein sequences in Primates, Muridae and Equids, we find different diversity patterns among the three amino-acids most critical for the DNA-recognition function, suggesting different diversification timescales.
Evolutionary Based Optimisation of Multivariable Fuzzy Control System of a Binary Distillation Column

Genetic Algorithms (GA), Simulated Annealing (SA) and Particle Swarm Optimisation (PSO) are population based stochastic search algorithms that categorised into the taxonomy of evolutionary optimisation. These methods have been employed independently to tune a fuzzy controller for maintaining the product compositions of a binary distillation column. An analytical investigation has been conducted to distinguish the optimal tuning approach of the controller among these techniques. Based on simulation results, particle swarm optimisation approach combined with the fuzzy controller is identified as a comparatively better configuration regarding its performance index and computational efficiency.
Baryons from supergravity

We study the construction of baryons via supergravity along the line suggested recently by Witten and by Gross and Ooguri. We calculate the energy of the baryon as a function of its size. As expected the energy is linear with N. For the non-supersymmetric theories (in three and four dimensions) we find a linear relation which is an indication of confinement. For the = 4 theory we obtain the result (EL = - const.) which is compatible with conformal invariance. Surprisingly, our calculation suggests that there is a bound state of k quarks if N ≥ k ≥ 5N/8. We study the = 4 theory also at finite temperature and find the zero temperature behavior for small size of the baryon, and screening behavior for baryon, whose size is large compared to the thermal wavelength.
Application of Image Processing Techniques for TV Broadcasting of Sporting Events

In this paper, we describe a system solution thanks to which virtual graphics, the projection of advertising images, logos, match scores and the distance measurements of players on the field may be overlaid on the plan of the different types of sports fields of real tested images. This solution relies on a study of the artificial vision and the Augmented Reality applied to TV broadcasting of sporting events where we have as input the original image to be processed, the image to be projected and the coordinates of the overlay position of the objects on the plan of the field. As an output, we have the overlaid objects in the processed image at the selected position in a more realistic way and in the background.
Please Scroll down for Article Journal of Homosexuality Cultural Value Orientations, Internalized Homophobia, and Accommodation in Romantic Relationships

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Expression Tree Evaluation by Dynamic Code Generation - Are Accelerators Up for the Task?

Dynamic code generation techniques are useful if the benefit of code specialized to values only known at runtime outweighs generation time. Such techniques are increasingly employed for HPC applications to tune their runtime behavior. The simulation software investigated in this paper is a typical example: It spends a significant portion of computing time evaluating symbolic formulas which are set up dynamically from model data. However, any software tuning has to match the hardware. Due to the so-called power wall, HPC systems are increasingly equipped with throughput-oriented accelerator components, to allow for rising performance as known from Top500 history. To best exploit such systems, it is important to understand how well applications map to heterogeneous components. While dynamic code generation can work well for standard multi-core systems, in this paper, we research the benefit of accelerators for this scenario. For our application we show that - while the generated code runs well on the accelerator - the generation itself has serious issues, and much better maps to standard multi-cores. Therefore, we see the need that coming HPC systems still have to be equipped with a significant portion of latency-oriented, thus complex general-purpose hardware.
Using multivariate resultants to find the intersection of three quadric surfaces

Macaulay’s concise but explicit expression for nmltivariate resultants has many potential applications in computer-aided geometric design. Here we describe its use in solid modeling for finding the intersections of three implicit quadric surfaces. By B6zout’s theorem, three quadric surfaces have either at most eight or intlnitely many intersections. Our method finds the intersections, when there are finitely many, by generating a polynomial of degree at most eight whose roots are the intersection coordinates along an appropriate axis. Only addition, subtraction, and multiplication are required to find the polynomial. But when there are pmsibilities of extraneous roots, division and greatest common divisor computations are necessary to identify and remove them.
The Role of Genetic Drift in Shaping Modern Human Cranial Evolution: A Test Using Microevolutionary Modeling

The means by which various microevolutionary processes have acted in the past to produce patterns of cranial variation that characterize modern humans is not thoroughly understood. Applying a microevolutionary framework, within- and among-population variance/covariance (V/CV) structure was compared for several functional and developmental modules of the skull across a worldwide sample of modern humans. V/CV patterns in the basicranium, temporal bone, and face are proportional within and among groups, which is consistent with a hypothesis of neutral evolution; however, mandibular morphology deviated from this pattern. Degree of intergroup similarity in facial, temporal bone, and mandibular morphology is significantly correlated with geographic distance; however, much of the variance remains unexplained. These findings provide insight into the evolutionary history of modern human cranial variation by identifying signatures of genetic drift, gene flow, and migration and set the stage for inferences regarding selective pressures that early humans encountered since their initial migrations around the world.
Electrolytic Gated Organic Field-Effect Transistors for Application in Biosensors—A Review

Electrolyte-gated organic field-effect transistors have emerged in the field of biosensors over the last five years, due to their attractive simplicity and high sensitivity to interfacial changes, both on the gate/electrolyte and semiconductor/electrolyte interfaces, where a target-specific bioreceptor can be immobilized. This article reviews the recent literature concerning biosensing with such transistors, gives clues to understanding the basic principles under which electrolyte-gated organic field-effect transistors work, and details the transduction mechanisms that were investigated to convert a receptor/target association into a change in drain current.
Multi-purpose passive debugging for embedded wireless

Debugging embedded wireless systems can be cumbersome and hard due to low visibility. To ease the task of debugging we propose a multi-purpose passive debugging framework, called TinyDebug, for developing embedded wireless systems. TinyDebug is designed to be used throughout the entire system development process, ranging from simulation to actual deployment. TinyDebug provides out-of-the-box message oriented debugging and event logging mechanism while enabling more advanced debugging techniques to process the same debug events.
Finding Opinion Manipulation Trolls in News Community Forums

The emergence of user forums in electronic news media has given rise to the proliferation of opinion manipulation trolls. Finding such trolls automatically is a hard task, as there is no easy way to recognize or even to define what they are; this also makes it hard to get training and testing data. We solve this issue pragmatically: we assume that a user who is called a troll by several people is likely to be one. We experiment with different variations of this definition, and in each case we show that we can train a classifier to distinguish a likely troll from a non-troll with very high accuracy, 82‐95%, thanks to our rich feature set.
Molecular Interaction between Projection Neuron Precursors and Invading Interneurons via Stromal-Derived Factor 1 (CXCL12)/CXCR4 Signaling in the Cortical Subventricular Zone/Intermediate Zone

Most cortical interneurons are generated in the subpallial ganglionic eminences and migrate tangentially to their final destinations in the neocortex. Within the cortex, interneurons follow mainly stereotype routes in the subventricular zone/intermediate zone (SVZ/IZ) and in the marginal zone. It has been suggested that interactions between invading interneurons and locally generated projection neurons are implicated in the temporal and spatial regulation of the invasion process. However, so far experimental evidence for such interactions is lacking. We show here that the chemokine stromal-derived factor 1 (SDF-1; CXCL12) is expressed in the main invasion route for cortical interneurons in the SVZ/IZ. Most SDF-1-positive cells are proliferating and express the homeodomain transcription factors Cux1 and Cux2. Using MASH-1 mutant mice in concert with the interneuron marker DLX, we exclude that interneurons themselves produce the chemokine in an autocrine manner. We conclude that the SDF-1-expressing cell population represents the precursors of projection neurons during their transition and amplification in the SVZ/IZ. Using mice lacking the SDF-1 receptor CXCR4 or Pax6, we demonstrate that SDF-1 expression in the cortical SVZ/IZ is essential for recognition of this pathway by interneurons. These results represent the first evidence for a molecular interaction between precursors of projection neurons and invading interneurons during corticogenesis.