Miracle-dz/UniFAR-FTUs huggingface dataset:
The optimization of fitting a mobile robot’s position and pose to its measured coordinates’ data by single vision

This paper is about a kind of mobile robot used to polish free form surface of large metal model above and a method is presented for fitting the robotpsilas configuration to the measured data obtained by machine vision system. In the close loop of control system of the robot, a single camera machine vision system is employed to measure robotpsilas position and pose. Due to 2D state data can only be obtained by signal camera, the real 3D parameters of robot must be calculated out when it is moving on uneven surface. But errors usually exist in the calculated data. Thus to obtain more accurate data about robotpsilas state, it is needed to fit the measured data group with the robotpsilas configuration. Base on genetic algorithm (GA), an optimal fitting method is proposed and better result is got.
Anti-idiotype-induced, lipopolysaccharide-specific antibody response to Pseudomonas aeruginosa. II. Isotype and functional activity of the anti-idiotype-induced antibodies.

We recently developed a murine anti-idiotypic mAb that functioned as a molecular mimic of the O-specific polysaccharide side chain (Ps) of Pseudomonas aeruginosa LPS in vitro, and which induced Ps-specific antibodies in syngeneic BALB/c ByJ mice. In the current studies, we demonstrate that these anti-Id-induced, Ps-specific antibodies fix complement to the bacterial cell surface, and protect neutropenic mice from fatal P. aeruginosa sepsis. The isotypic distribution of the anti-Id-induced antibodies, however, resembles the restricted pattern (IgM and IgG3) seen after administration of purified Ps to mice. The immunogenicity and number of isotypes of Ps-specific antibody produced could be enhanced by conjugating the anti-Id to keyhole limpet hemocyanin. Finally, the anti-Id administered before immunization with purified Ps, primed BALB/c ByJ mice for production of other Ps-specific antibody isotypes (IgG1). These studies show that this anti-Id induces functional anti-Ps antibodies in syngeneic mice, and when used in conjugate form or as a priming agent before Ps immunization, yields an antibody response consistent with "T cell dependence. " These immunization strategies may be useful for the induction of polysaccharide-specific antibodies in man.
A Note on Central Place Theory and the Range of a Good

Od NE important element in central place theory is the notion of the range of a good.1 This range marks out the zone or tributary area around a central place (urban center) from which persons travel to the center to purchase the good, ". a product of the simultaneous spatial effects of all the factors of demand and supply involved in the purchase of central goods and services. "2 The upper limit of the range is the maximum possible radius of sales. Beyond the upper limit the price of the good is too high for it to be sold, either because of the increase of price with distance until consumers will no longer purchase the good (the ideal limit where demand becomes zero), or because of the greater proximity of consumers to an alternate competing center (the real limit). The range also has a lower limit, that radius
Olive oil intake and CHD in the European Prospective Investigation into Cancer and Nutrition Spanish cohort

Olive oil is well known for its cardioprotective properties; however, epidemiological data showing that olive oil consumption reduces incident CHD events are still limited. Therefore, we studied the association between olive oil and CHD in the European Prospective Investigation into Cancer and Nutrition (EPIC) Spanish cohort study. The analysis included 40 142 participants (38 % male), free of CHD events at baseline, recruited from five EPIC-Spain centres from 1992 to 1996 and followed up until 2004. Baseline dietary and lifestyle information was collected using interview-administered questionnaires. Cox proportional regression models were used to assess the relationship between validated incident CHD events and olive oil intake (energy-adjusted quartiles and each 10 g/d per 8368 kJ (2000 kcal) increment), while adjusting for potential confounders. During a 10·4-year follow-up, 587 (79 % male) CHD events were recorded. Olive oil intake was negatively associated with CHD risk after excluding dietary mis-reporters (hazard ratio (HR) 0·93; 95 % CI 0·87, 1·00 for each 10 g/d per 8368 kJ (2000 kcal) and HR 0·78; 95 % CI 0·59, 1·03 for upper v. lower quartile). The inverse association between olive oil intake (per 10 g/d per 8368 kJ (2000 kcal)) and CHD was more pronounced in never smokers (11 % reduced CHD risk (P = 0·048)), in never/low alcohol drinkers (25 % reduced CHD risk (P < 0·001)) and in virgin olive oil consumers (14 % reduced CHD risk (P = 0·072)). In conclusion, olive oil consumption was related to a reduced risk of incident CHD events. This emphasises the need to conserve the traditional culinary use of olive oil within the Mediterranean diet to reduce the CHD burden.
Bipartite vectors for co‐expression of a growth factor cDNA and short hairpin RNA against an apoptotic gene

Although human islet transplantation is a promising approach for treating type I diabetes, its success is limited as a result of the poor survival rate of transplanted islets. Expression of a growth factor gene to promote revascularization and silencing of pro‐apoptotic genes before transplantation may improve the outcome of islet transplantation.
Qualifikation, Kompetenz und Personalentwicklung –Zum Einfluss von Informations- und Kommunikationstechnik auf Bankmitarbeiter

Anlässe für die nachhaltige Veränderung von Organisationen sind zahlreich. Als besonders einflussreich hat sich in der vergangenen Dekade jedoch die Wirkung der Informationsund Kommunikationstechnik erwiesen. Speziell für Banken stellt dieser Entwicklungspfad Ursache und Zwang zu nachhaltiger Veränderung dar, aber darüber hinaus auch die Option für deren erfolgreiche Bewältigung. Vor diesem Hintergrund wird in der Dissertation das Spannungsfeld des technikinduzierten Wandels deutscher Banken untersucht. Konkret wird erforscht, welcher Art die personalwirtschaftlichen Konsequenzen beim Einsatz von Technik an der Schnittstelle zwischen Kunde und Bank sind. Das Spektrum personalwirtschaftlicher Betätigungsfelder wird dabei auf die Untersuchungsvariablen Qualifikation und Kompetenz eingeschränkt. Maßgeblich für diese Entscheidung ist die Interpretation von Banken als sozio-technische Systeme: Im Mittelpunkt des bankbetrieblichen Leistungsprozesses stehen eben nicht nur technische ‚Apparaturen’, sondern auch Personen in ihrer Rolle als Mitarbeiter. Ausgangspunkt der Überlegungen ist, dass vor Einführung neuer Techniken im Bankbereich ein Zustand existiert, der sich als „Qualifikationsund Kompetenzgleichgewicht“ interpretieren lässt, in dem die angebotenen Qualifikationen und die nachgefragten Kompetenzen übereinstimmen. Dieser Zustand erfährt einen exogenen „Schock“: Informationsund Kommunikationstechnik wird von Banken als hilfreich erkannt und in großem Umfang eingesetzt. Dies führt zu einer Störung des ursprünglichen Gleichgewichtszustandes: Die traditionellen Tätigkeitsinhalte der Mitarbeiter im Retail Banking ändern sich innerhalb verhältnismäßig kurzer Zeit erheblich, so dass die angebotenen Qualifikationen den nachgefragten Kompetenzen nicht mehr entsprechen. Um das Gleichgewicht zwischen Qualifikationen und Kompetenzen wieder herzustellen, sind Anpassungsmaßnahmen der Banken erforderlich. Ein sich einstellendes Gleichgewicht wird sich dabei bezüglich seiner Merkmale vom ursprünglichen Gleichgewicht unterscheiden. Das Ziel der Arbeit besteht darin, den neuen Gleichgewichtszustand theoretisch herzuleiten und hinsichtlich seiner normativen Eigenschaften zu untersuchen, um darauf aufbauend Gestaltungsempfehlungen für den Anpassungsprozess ableiten zu können. Dieses Vorgehen ist aufgrund der vergleichenden
Identification of potential diagnostic and therapeutic target genes for lung squamous cell carcinoma

The purpose of this study was to identify potential molecular markers of lung squamous cell carcinoma (LUSC). Three datasets containing LUSC mRNA sequencing data were downloaded from the Gene Expression Omnibus, The Cancer Genome Atlas and the Gene Expression Profiling Interactive Analysis databases. These datasets were used to identify significantly differentially expressed genes (DEGs) in LUSC. A protein-protein interaction network of the DEGs was constructed followed by Gene Ontology, Kyoto Encyclopedia of Genes and Genomes and overall survival analyses of the DEGs. A total of 37 DEGs between LUSC and normal tissues were identified, including 26 downregulated genes and 11 upregulated genes. Biological Process enrichment analysis revealed that the DEGs were mainly enriched in ‘cell adhesion’, ‘cell-matrix adhesion’, ‘anatomical structure morphogenesis’, ‘ECM-receptor interaction’ and ‘focal adhesion’. Overall survival analysis demonstrated that transcription factor 21, α-2-macroglobulin, acyl-CoA synthetase long chain family member 5, integrin subunit β8, meiotic nuclear divisions 1 and secretoglobin family 1A member 1 were significantly associated with the occurrence and development of lung cancer, and these genes were selected as hub genes. The results obtained in the present study may aid the elucidation of the molecular mechanisms involved in the development of LUSC and may provide potential targets for LUSC treatment.
GALACTIC COSMIC RAY ORIGINS AND OB ASSOCIATIONS: EVIDENCE FROM SuperTIGER OBSERVATIONS OF ELEMENTS 26Fe THROUGH 40Zr

We report abundances of elements from 26Fe to 40Zr in the cosmic radiation measured by the SuperTIGER (Trans-Iron Galactic Element Recorder) instrument during 55 days of exposure on a long-duration balloon flight over Antarctica. These observations resolve elemental abundances in this charge range with single-element resolution and good statistics. These results support a model of cosmic ray origin in which the source material consists of a mixture of % material from massive stars and ∼81% normal interstellar medium material with solar system abundances. The results also show a preferential acceleration of refractory elements (found in interstellar dust grains) by a factor of ∼4 over volatile elements (found in interstellar gas) ordered by atomic mass (A). Both the refractory and volatile elements show a mass-dependent enhancement with similar slopes.
Prospective study of three major dietary patterns and risk of gastric cancer in Japan

Dietary pattern analysis is an alternative and complementary approach to identify the relationship between diet and the risk of chronic disease. This study was aimed at investigating the associations between dietary patterns and the risk of gastric cancer in Japan. Using baseline data from a prospective study of 20,300 men and 21,812 women, we conducted factor analysis and identified 3 major dietary patterns, healthy, traditional and Western, and calculated the factor scores of each pattern for individuals. During 10 years of follow‐up, 400 cases of gastric cancer were identified. We found an inverse association between the healthy pattern and gastric cancer risk in women [rate ratio for highest quartile (RR) = 0.56; 95% CI = 0.32–0.96; p for trend = 0.03], but not in men. In contrast, the traditional pattern was significantly associated with the increased risk of gastric cancer in both genders (for men, RR = 2.88, 95% CI = 1.76–4.72; for women, RR = 2.40, 95% CI = 1.32–4.35). The Western pattern was not associated with risk. These associations persisted in histologic subtypes. Our findings support the idea that the healthy pattern decreased the risk of gastric cancer among females, while the traditional pattern increased the risk in both genders. © 2004 Wiley‐Liss, Inc.
Rate maximization in space-division multiple access (SDMA) /multi-input-single-output (MISO) /OFDM systems under QoS and power constraints

This paper considers the resource allocation problem in space-division multiple access (SDMA)/multi-input-single-output (MISO)/OFDM systems. Our objective function is to maximize the total system data rate subject to total power constraint and each user's quality-of-service (QoS) requirement. In this SDMA/MISO/OFDM multiuser system, each user possesses a spatial filter in each subcarrier to remove interference from other users in that subcarrier. We observe that the number of users in a subcarrier has two conflicting effects on the system throughput. Adding more users in a subcarrier increases the number of spatial channels; however, at the same time, it introduces more interference among the users which reduces the throughput in each spatial channel. This paper takes into consideration these effects to solve the rate maximization problem.
Identification of the Interactions among the Power System Dynamic Voltage Stability Controllers using Relative Gain Array

This paper concerns the use of relative gain array (RGA) for analyzing the interactions among the power system dynamic voltage stability controls. RGA analyses for both static and dynamic voltage stability controls are carried out based on the multi-input multi-output (MIMO) transfer function matrix Jv(s). By means of the singular value and RGA, the dynamic voltage stability and the controller interactions are analyzed. Then, the dynamic voltage stability control loop can be selected. A multi-machine power system with different working conditions is simulated for the demonstration of the proposed approach. Also, limitations and advantages of the use of singular value and RGA in the dynamic voltage stability analysis and control are discussed. The proposed approach is simple and can be easily implemented into large power system dynamic voltage stability control
Targeting prostate cancer with HTI‐286, a synthetic analog of the marine sponge product hemiasterlin

Therapeutic resistance is the underlying cause for most cancer deaths and a major problem associated with treatment of metastatic prostate cancer. HTI‐286, a fully synthetic analog of the natural tripeptide hemiasterlin, inhibits tubulin polymerization and circumvents transport‐based resistance to taxanes. In our study, we evaluated its inhibitory effects on human prostate cancer growth in vitro and in different in vivo models. Androgen‐dependent and androgen‐independent prostate cancer cell lines including a docetaxel‐refractory PC‐3 subline (PC‐3dR) were treated with HTI‐286. Transcriptional profiling was carried out to screen for changes in gene expression induced by HTI‐286 and compared to docetaxel. In vivo, nude mice with established PC‐3 or PC‐3dR xenografts were given HTI‐286 intravenously. Additionally, mice bearing hormone‐sensitive LNCaP tumors were treated with castration in combination with early or delayed HTI‐286 therapy. In all cell lines tested, HTI‐286 was a potent inhibitor of proliferation and induced marked increases in apoptosis. Despite similar transcriptomic changes regarding cell death and cell cycle regulating genes after exposure to HTI‐286 or docetaxel, array analysis revealed distinct molecular signatures for both compounds. Invivo, HTI‐286 significantly inhibited growth of PC‐3 and LNCaP xenografts and retained potency in PC‐3dR tumors. Simultaneous castration plus HTI‐286 therapy was superior to sequential treatment in the LNCaP model. In conclusion, HTI‐286 showed strong antitumor activity both in androgen‐dependent and androgen‐ independent tumors and may be a promising agent in second‐ line treatment strategies for patients suffering from docetaxel‐ refractory prostate cancer. © 2008 Wiley‐Liss, Inc.
Practical Considerations on Channel Estimation for Up-Link MC-CDMA Systems

Channel parameters, which are usually estimated at the receiver, are required in signal detection in multi-carrier (MC) code division multiplex access (CDMA). The accuracy of channel estimation directly affects the performance of the overall system. In this paper, we present some practical techniques to improve channel estimation in up-link MC-CDMA systems. For most of multipath channels, there are only a few significant taps in time domain that determine the frequency response. Based on this characteristic, we detect and keep these significant taps and discard the trivial ones, which are usually very noisy or contain only noise components. After channel parameters are estimated at the pilot blocks, channels at the data blocks can be obtained by interpolation. To improve the performance of simple linear interpolation, we apply optimal interpolation, which takes channel estimation error and channel correlation into consideration. We then investigate the impact of channel estimation error on minimum mean-square-error (MMSE) successive interference cancellation (SIC) detector and find that more accurate channel is required to further improve the performance of the MMSE SIC detector. Therefore, we develop soft-decision-directed (SDD) channel estimation, which exploits the information at the data blocks to improve channel estimation.
Effect of chondroitin sulfate on intraocular pressure in rats.

PURPOSE To study the effect of intracameral injections of chondroitin sulfate (CS) on intraocular pressure (IOP), retinal function, and histology in rats. METHODS Acute or chronic injections of CS were performed unilaterally in the rat anterior chamber, whereas the contralateral eye was injected with vehicle. IOP was daily or weekly assessed by a tonometer. Retinal function was assessed by scotopic electroretinography (ERG) and the visual pathway by flash visual evoked potentials (VEPs), whereas the retinal and optic nerve head structure were examined by histologic analysis. RESULTS A single injection of 8 mg (but not 2 or 4 mg) CS induced a significant increase of IOP. The increase of IOP induced by a single injection of 8 mg CS lasted for 7 days, whereas chronic (weekly) administration during 10 weeks induced a significant and sustained increase in IOP compared with eyes injected with vehicle. A significant decrease of scotopic ERG a- and b- wave amplitude was observed after 6 and 10 weeks of CS administration. Moreover, a significant decrease in scotopic flash VEP N2-P2 component amplitude was observed in eyes treated with CS for 6 and 10 weeks. A significant loss of ganglion cell layer cells and optic nerve axons was observed in eyes receiving CS for 10 weeks. CONCLUSIONS These results suggest that exogenous CS simulates the accumulation of CS in primary open-angle glaucoma and that increased amounts of CS could play a key role in the IOP dysregulation characteristic of glaucoma.
Symmetrical Serotonin Release during Asymmetrical Slow-Wave Sleep: Implications for the Neurochemistry of Sleep–Waking States

On land, fur seals predominately display bilaterally synchronized electroencephalogram (EEG) activity during slow-wave sleep (SWS), similar to that observed in all terrestrial mammals. In water, however, fur seals exhibit asymmetric slow-wave sleep (ASWS), resembling the unihemispheric slow-wave sleep of odontocetes (toothed whales). The unique sleeping pattern of fur seals allows us to distinguish neuronal mechanisms mediating EEG changes from those mediating behavioral quiescence. In a prior study we found that cortical acetylcholine release is lateralized during ASWS in the northern fur seal, with greater release in the hemisphere displaying low-voltage (waking) EEG activity, linking acetylcholine release to hemispheric EEG activation (Lapierre et al. 2007). In contrast to acetylcholine, we now report that cortical serotonin release is not lateralized during ASWS. Our data demonstrate that bilaterally symmetric levels of serotonin are compatible with interhemispheric EEG asymmetry in the fur seal. We also find greatly elevated levels during eating and hosing the animals with water, suggesting that serotonin is more closely linked to bilateral variables, such as axial motor and autonomic control, than to the lateralized cortical activation manifested in asymmetrical sleep.
The negative alpha filter: a new Processing technique for polarimetric SAR interferometry

In this letter we develop a new concept, the negative alpha filter, which we suggest has application for quantitative estimation of surface parameters beneath vegetation using polarimetric synthetic aperture radar (SAR) interferometry (POLInSAR). We first derive the filter and then validate it using simulations of L-band coherent forest scattering. We then show initial results of applying the filter to airborne data from the German Aerospace Center's E-SAR L-band sensor.
Activity scheduling as a core component of effective care management for late‐life depression

Activity scheduling is an established component of evidenced‐based treatment for late‐life depression in primary care. We examined participant records from the Improving Mood‐Promoting Access to Collaborative Treatment (IMPACT) trial to identify activity scheduling strategies used in the context of successful depression care management (CM), associations of activity scheduling with self‐reported activity engagement, and depression outcomes.
Shape Reconstruction from an Endoscope Image by Shape from Shading Technique for a Point Light Source at the Projection Center

This paper presents a method for reconstructing the 3D shape of an object from its endoscope image based on image shading. The primary problem is that the endoscope has a light source near the object surface. Most of the conventional shape from shading methods assumed that the light source was distant from the object surface and simplified the analysis. To deal with the near light source, we use the configuration of the endoscope that the light source of the endoscope is well approximated by an imaginary point source at the projection center. In addition, we introduce a notion of equal distance contours of the object surface; by propagating the contours using the image shading, we reconstruct the object shape. This is an extension of the Kimmel? Bruckstein algorithm of shape from shading to the endoscope images. Experimental results for real medical endoscope images of the stomach wall show the feasibility of this method and also show its promising availability for morphological analyses of tumors on human inner organs.
Bankruptcy Costs and the Firm's Optimal Debt Capacity: A Positive Theory of Capital Structure

independent of its capital structure is a conceptual subject which continues to receive considerable attention and discussion in recent financial theory literature.1 The basic underlying premise of the M-M proposition is simply that in perfect securities markets, the capital structure decisions by firms belonging to the same risk class do not alter the opportunity set available to investors. Hence any discrepancies in total market values of identical firms in the same risk class arising from differences in financing mix will be removed through arbitrage operations by investors. But as recent financial writers point out, individual investors do not enjoy the limited liability priviledge accorded to firms, and more significantly, there are explicit costs to bankruptcy which may offset the advantage to the firm arising from the tax deductibility of interest payments. Hence the purpose of this paper is to examine in a formal manner, within the context of a mean-variance framework, if recognition of these securities market imperfections are sufficient to establish the traditional finance position that capital structure decisions have a significant impact on total firm value, and thereby provide the theoretical basis for a financial synergy rationale for conglomerate