Miracle-dz/UniFAR-FTUs huggingface dataset:
PLACE BUILDING AND MISSION STATEMENTS: A MATCH OR MISFIT? *

The purpose of this study was to investigate possible relationships between organizational Mission Statements (MS) and Pace Building (PB). The basic question addressed in the study was do corporate MS statements contain a linkage to their possible place building strategies. Do the linkages suggest a match, a misfit, or is the linkage missing? Place building focuses on how an organization values the dimensions of place: nature, social relationships, material environment, ethics, and economic relationships in relation to the places in which they are located. We examined the MS from 41 businesses selected among a group of fortune 500 firms to determine if place building attributes were evident. Qualitative document analysis was employed to investigate the possible linkage between mission statements and the concepts of the place building model. The findings of the study suggest that corporate mission statements most often fail to address the strategies associated with organizational place building. These findings raise important questions for discussion regarding the future of organizations and their relationship to place building in the community: how is corporate space used in the community, what is the condition of the space, and what is the impact of organizational place on the community resources. The study concludes that the strategy of addressing place/community relations within corporate mission statements can provide a useful way forward in addressing the foregoing questions.
The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer

Abstract The HSF and FOXO families of transcription factors play evolutionarily conserved roles in stress resistance and lifespan. In humans, the rs2802292 G-allele at FOXO3 locus has been associated with longevity in all human populations tested; moreover, its copy number correlated with reduced frequency of age-related diseases in centenarians. At the molecular level, the intronic rs2802292 G-allele correlated with increased expression of FOXO3, suggesting that FOXO3 intron 2 may represent a regulatory region. Here we show that the 90-bp sequence around the intronic single nucleotide polymorphism rs2802292 has enhancer functions, and that the rs2802292 G-allele creates a novel HSE binding site for HSF1, which induces FOXO3 expression in response to diverse stress stimuli. At the molecular level, HSF1 mediates the occurrence of a promoter–enhancer interaction at FOXO3 locus involving the 5′UTR and the rs2802292 region. These data were confirmed in various cellular models including human HAP1 isogenic cell lines (G/T). Our functional studies highlighted the importance of the HSF1-FOXO3-SOD2/CAT/GADD45A cascade in cellular stress response and survival by promoting ROS detoxification, redox balance and DNA repair. Our findings suggest the existence of an HSF1-FOXO3 axis in human cells that could be involved in stress response pathways functionally regulating lifespan and disease susceptibility.
How did the publication of the book The Machine That Changed The World change management thinking? Exploring 25 years of lean literature

Purpose – The purpose of this paper is to take a critical, analytical approach to explore the growth and spread of Lean through the academic and practitioner community over the last 25 years to understand the impact of the book The Machine that Changed the World on management thinking. Design/methodology/approach – A comprehensive and systematic review of the extant literature of lean was undertaken and analysed critically to observe patterns and trends that could explain the acceptance of Lean as an operations management philosophy. The review spans from 1987 to 2013. To enable us to effectively manage and understand the diffusion of this literature a database, the Lean Publications Database, was constructed. The number of publications has been adjusted to compensate for growth in the total number of articles published in the same period. Findings – Lean has evolved to be one of the best-known, yet fiercely debated, process improvement methodologies. It emerged during a proliferation of such methodologie.
Countering Prejudice against American Indians and Alaska Natives through Antibias Curriculum and Instruction. ERIC Digest.

Countering Prejudice against American Indians and Alaska Natives through Antibias Curriculum and Instruction. ERIC Digest. 1 CURRENT TEACHING ABOUT NATIVE AMERICANS. 2 DEVELOPING ANTIBIAS NATIVE AMERICAN CURRICULUM. 3 DETECTING ANTI-INDIAN BIAS IN INSTRUCTIONAL MATERIALS.5 CONCLUSION. 6 REFERENCES. 7
A switched second-order sliding mode control algorithm for non-affine systems with saturations

In control systems design, the problem of managing dynamical systems affected by uncertainties that are different in different region of the state space, or with closed-loop specification that should be adjusted to the current operating condition must be often faced. To adapt the controller performance to these spatially-varying phenomena, switched solutions proved to be effective and more easily manageable than conventional adaptive ones. Within this context, this paper addresses the problem of designing a switched sliding mode controller for a class of nonlinear non-affine systems with saturating actuators. The original system is first reduced to an affine form, thus defining a new system which is assumed to be affected by unknown, yet bounded, uncertainties that are different in different regions of the state space. For such system, a switched second order sliding mode control algorithm is designed which can cope with saturating actuators present in the original non-affine system. The control law is proved to ensure finite-time convergence to the origin of the closed-loop trajectory, and a simulation example is given to assess the performance of the proposed approach.
Predictive Maintenance Optimization for Aircraft Redundant Systems Subjected to Multiple Wear Profiles

Researchers and industry practitioners have recently demonstrated great interest in maintenance planning since it directly impacts the lifecycle cost and availability of systems. Considering the aviation industry, this impact is even more relevant due to high-availability expectations from aircraft operators and high costs incurred when an aircraft becomes out of service. For this reason, some minor maintenance activities are carried out near the gate, between two consecutive flight legs. These activities are referred to as aircraft line maintenance. The usage of prognostics and health management techniques may help the prevention of unexpected events when caused by degrading components. The application of prognostics techniques together with a line maintenance planning optimization approach is not a trivial task and requires sophisticated mathematical approaches especially when dealing with complex and integrated systems. This paper proposes a methodology for predictive line maintenance optimization of redundant aeronautical systems subjected to multiple wear conditions. Degradation trends and future wear values are estimated considering an implementation of a multiple model approach of the extended Kalman filter technique. Planning optimization is based on the minimization of operational costs comprising several aspects of the aviation industry such as dispatch requirements, delays, cancellations, and equipment costs. A case study is conducted using field prognostics data of hydraulic systems to evidence the efficiency and benefit of the proposed methodology.
On Restricted Disjunctive Temporal Problems: Faster Algorithms and Tractability Frontier

In 2005 Kumar studied the Restricted Disjunctive Temporal Problem (RDTP), a restricted but very expressive class of disjunctive temporal problems (DTPs). It was shown that that RDTPs are solvable in deterministic strongly-polynomial time by reducing them to the Connected Row-Convex (CRC) constraints problem; plus, Kumar devised a randomized algorithm whose expected running time is less than that of the deterministic one. Instead, the most general form of DTPs allows for multi-variable disjunctions of many interval constraints and it is NP-complete. This work offers a deeper comprehension on the tractability of RDTPs, leading to an elementary deterministic strongly-polynomial time algorithm for them, significantly improving the asymptotic running times of both the deterministic and randomized algorithms of Kumar. The result is obtained by reducing RDTPs to the Single-Source Shortest-Paths (SSSP) and the 2-SAT problem (jointly), instead of reducing to CRCs. In passing, we obtain a faster (quadratic-time) algorithm for RDTPs having only Type-1 and Type-2 constraints (and no Type-3 constraint). As a second main contribution, we study the tractability frontier of solving RDTPs by considering Hyper Temporal Networks (\HTNs), a strict generalization of \STNs grounded on hypergraphs: on one side, we prove that solving temporal problems having only Type-2 constraints and either only multi-tail or only multi-head hyperarc constraints lies in both NP and co-NP and it admits deterministic pseudo-polynomial time algorithms; on the other side, solving problems with Type-3 constraints and either only multi-tail or only multi-head hyperarc constraints turns strongly NP-complete.
Towards systemic management of diversity in organizational change

This article: Reflects critically upon the approaches to managing organizational change. It is argued that current approaches are normally single-method-led, dominated by reductionism and isolationism. Reviews how contemporary systems thinking manages methodological diversity, to inform managing organizational change. Develops a systemic framework, which includes a classification of four ideal types of diversity and four approaches in organizational change. Copyright © 1999 John Wiley & Sons, Ltd.
Revised competencies for private club managers

Purpose – This study was conducted with the aim of examining important and frequently used managerial competencies for private club managers. Sandwith's five‐competency domain model was applied to private club managers who were members of the Club Managers Association of America (CMAA). Design/methodology/approach – A total of 800 private club managers from throughout the USA were invited to participate in this study. Managers were randomly selected from the Club Managers Association of America (CMAA) membership list.Findings – This study investigated managerial competencies for private club managers. A total of 28 competencies were classified as essential competencies, 120 were classified as considerably important competencies, and three were classified as moderately important competencies for private club managers. These were classified into five domains: the conceptual/creative domain, the leadership domain, the administrative domain, the interpersonal domain, and the technical domain. Leadership and in.
Cloning and Characterization of a Novel Integrin b 3 Subunit *

We have identified a novel integrin b3 subunit, termed b3C, from a human osteoclast cDNA library. The COOHterminal sequence and 3*-untranslated region of the b3C subunit differs from the previously reported b3A (platelet) and b3B (placenta) sequences, while the regions coding for the transmembrane and extracellular domains are identical. The b3C cytoplasmic domain contains 37 amino acids, the last 17 of which are encoded by a novel exon located about 6 kilobase pairs downstream of exon 14 of the b3A gene. HEK 293 cells were stably co-transfected with aV and either b3C (HEKb3C) or b3A (HEKb3A). The viability of HEKb3C cells was lower than that of HEKb3A cells, and HEKb3C cells in culture grew as clusters rather than as a monolayer. The novel cytoplasmic domain did not affect receptor binding affinity; both aVb3A and aVb3C isoforms exhibited high affinity binding to I-echistatin and cyclic and linear RGD peptides. However, in contrast to HEKb3A, HEKb3C cells failed to adhere to osteopontin, an aVb3 matrix protein. The data provide further support for the key role of the cytoplasmic domain of the b3 integrin in cell adhesion and suggest a potential role for the b3C integrin subunit in modulating cell-matrix interactions.
Treatment of a Patient with Cleft Lip and Palate Using an Internal Distraction Device

A 24-year-old man with a bilateral cleft lip and palate was treated by a multidisciplinary team composed of an orthodontist, plastic surgeon, and prosthodontist with assistance from an engineer. Before treatment, clinical photographs, dental casts, lateral and posteroanterior cephalograms, periapical and panoramic radiographs, and three-dimensional computed tomography (3D CT) images were obtained. He presented with a narrow and retrognathic maxilla with a 23-mm anterior open bite. Following maxillary expansion with rapid palatal expansion, a Le Fort I maxillary osteotomy was performed, and an internal distractor was placed. After a 5-day latency period, internal maxillary distraction was performed at a rate of 1 mm/day achieved by two activations per day. Cephalometric analysis showed a 7-mm maxillary advancement. Mandibular bilateral sagittal split osteotomy was also performed to close the open bite following maxillary distraction and a 3-month stabilization period. Finally, the treatment was completed with prosthetic rehabilitation. The changes in speech production were evaluated using an automatic speech recognition system.
Nomogram for predicting survival in patients with pancreatic cancer

Background The purpose of this study was to develop a nomogram to predict cancer-specific survival (CSS) in pancreatic cancer (PC). Patients and methods We used the Surveillance, Epidemiology, and End Results (SEER) database to analyze 53,028 patients diagnosed with PC from 2004 to 2014 and randomly divided them into the training (n=26,583) cohort and validation (n=26,445) cohort. Univariate and multivariate analyses were used to select independent prognostic factors. We used significant prognostic factors for constructing a nomogram based on Cox regression analyses. Validation of the nomogram was assessed by discrimination and calibration. Results According to the multivariate models of training cohort, a nomogram that combined age, race, tumor location, marital status, tumor size, TNM stage, tumor grade, and surgery was constructed for predicting CSS. The internally validated and externally validated C-indexes were 0.741 and 0.734, respectively. The calibration curves showed that the nomogram was able to predict 1-, 3-, and 5-year CSS accurately. Conclusion A nomogram effectively predicts survival in patients with PC. This prognostic model may be considered for use in clinical practice.
Convergence Clubs: Some Further Evidence

This paper investigates convergence patterns among 113 market economies. Incorporating different grouping methods, both ADF (augmented Dicke-Fuller) tests and KPSS (Kwiatkowski, Phillips, Schmidt, Shin) tests are used to examine whether countries converge to the group average. The test results support the finding of a "convergence club," and specifically, that the highest income countries converge and the lowest income countries diverge. Copyright 1999 by Blackwell Publishing Ltd.
Distinct evening fatigue profiles in oncology outpatients receiving chemotherapy

ABSTRACT Background: Fatigue is the most common and debilitating symptom experienced by oncology patients during chemotherapy (CTX). Fatigue severity demonstrates a large amount of inter-individual and diurnal variability. Purpose: Study purposes were to evaluate for subgroups of patients with distinct evening fatigue profiles and evaluate how these subgroups differed on demographic, clinical, and symptom characteristics. Methods: Outpatients with breast, gastrointestinal, gynecological, or lung cancer (n = 1332) completed questionnaires six times over two cycles of CTX. Lee Fatigue Scale evaluated evening fatigue severity. Latent profile analysis was used to identify distinct evening fatigue profiles. Results: Four distinct evening fatigue classes (i.e. Low (14.0%), Moderate (17.2%), High (36.0%), and Very High (32.8%)) were identified. Compared to the Low class, patients in the Very High evening fatigue class were: younger, female, had childcare responsibilities, had more years of education, had a lower functional status, had a higher comorbidity burden, and were diagnosed with breast cancer. Patients in the Very High class reported higher levels of depressive symptoms, sleep disturbance, and evening fatigue at enrollment. Conclusions: Findings provide new insights into modifiable risk factors for higher levels of evening fatigue. Clinicians can use this information to identify higher risk patients and plan appropriate interventions.
To Study Body Mass Index, Waist Circumference, Waist Hip Ratio,Body Adiposity Index And Lipid Profile Level In Patients With Type-2 Diabetes Mellitus

The prevalence of diabetes is rapidly rising all over the globe at an alarming rate. Diabetes is second only to cardiovascular disease (CVD) as a health burden in India. Type 2 diabetes is commonly associated with obesity, hypertension, CVD and lipid abnormalities. Aims and objectives: The aim of the study is to assess the BMI, WC, WHR, BAI and lipid profile in controlled and uncontrolled type 2 diabetes mellitus patients and to compare the above values with the controlled diabetic patients. Method: N=30 diabetic patients of either sex of age group between 35-50 years were selected from the Diabetic Clinic of Govt Medical College, Aurangabad, Maharashtra. Fasting lipid profile and HbA1C blood samples were taken. N=15 controlled Type 2 diabetes mellitus patients were diagnosed based on HbA1C below 7 and N=15 uncontrolled Type 2 diabetes mellitus patients were diagnosed based on HbA1C equal and above 7. BMI, WC, WHR, BAI were measured according to a standard protocol. Conclusions: Our data suggests that BAI, BMI, WC, Waist: Hip ratio and lipid values were higher in uncontrolled DM patients as compared to controlled DM patients.
Q-BT: Queue-Based Burst Transmission Over an Asynchronous Duty-Cycle MAC Protocol

In this letter, we tackle the channel contention and hidden terminal problems of asynchronous duty-cycle MAC protocols under heavy traffic scenario. To resolve the problems, we design a queue-based burst transmission MAC protocol (Q-BT), which couples burst (and fast) transmission and asynchronous duty-cycle features together by using queue length information. We evaluate its performance in a multihop testbed, which shows that our proposal improves packet reception ratio and duty-cycle performance by 70.2% and 59.1%, respectively, at a maximum compared to BoX-MAC (i.e., the default MAC in TinyOS).
Congenital Carotid–Jugular Fistula in a Child

Congenital carotid–jugular (CJ) fistula of the neck is a very rare clinical entity that has various causes. The CJ fistulas are particularly prone to complications unlike other peripheral arteriovenous fistulas. The aim of this report is to present a case of a CJ fistula between the external carotid and the external jugular vein, which was successfully closed with detachable balloon by an endovascular approach. A 14-year-old child was admitted to our clinic with a pulsatile neck swelling. There was no previous history of trauma. A high-flow fistula between the external carotid and the external jugular vein was determined. The fistula was closed with detachable balloon by an endovascular approach. The postoperative angiogram demonstrated complete resolution of the fistula. Endovascular treatment of CJ fistulas with detachable balloons is a safe and less traumatic technique and may be an effective alternative to the open surgery in selected patients.
New Datasets on Political Institutions and Elections, 1972—2005

This article introduces two new datasets produced by the Institutions and Elections Project.Those datasets contain nuanced information describing the political institutions, the constitutional and practical arrangements in governments, and every national election for every country in the international system between 1972 and 2005.We believe the 127 variables in these data represent a significant contribution to research programs in comparative and world politics interested in the nuances of domestic politics.
The Economic Impact of Capital Expenditures: Environmental Regulatory Delay as a Source of Strategic Advantage?

This study investigates the impact of environmental regulatory delay on capital market reactions to capital expenditure announcements. Using the time to gain resource consent (regulatory) approval as an indicator of expected resource consent compliance costs, positive valuation effects are found from project announcements when the expected time to gain resource consent approval is long. The findings suggest that by undertaking voluntary capital expenditures with high environmental compliance costs, listed companies can create strategic advantages. For example, long consent times may improve firms’ opportunities to develop specialised capabilities such as early mover advantages, reputational benefits, or enhanced environmental management systems. Alternatively, high environmental compliance costs may inhibit actions by industry competitors and new entrants, resulting in greater expected project NPVs.
Improving the Learning Experience by Harnessing Digital Technology

The paper will explore how a social media based E-learning 2.0 solution for formal learning (social IS) can be implemented, focusing on the technology acceptance process. The paper aims to increase the knowledge on how the acceptance regarding social media based E-learning 2.0 information systems for formal learning can be increased and how the acceptance affects the social learning experience. To achieve this, the paper relies on both a qualitative and quantitative approach and is primarily inductive. The paper concludes that the acceptance cannot be seen as a linear process, as is common practice. Instead, one should see the process of acceptance as interlinked with the experience and external variables in a continuous process that can either ‘spiral’ upwards or downwards. Furthermore, the paper identifies the problem of innovation resistance. The paper then analyzes information gathered from industry experts, practitioners and a live case to find how one can improve acceptance and thereby the social learning experience. Once these variables have been identified the paper presents strategic advice. The paper ends by a discussion of the results, both regarding the impact and contrast to previous research as well as highlighting areas for further research.