Miracle-dz/UniFAR-FTUs huggingface dataset:
Design and implementation of low cost microwave Full Duplex system based on WiFi cards for transmission over long distance

Rural areas in Africa have little access to information technologies because of the enormous cost of investments in telecommunications equipments. The aim of this paper is to design a microwave Full Duplex and full IP system based on WiFi technology in order to transmit data over long distance. This system could serve rural areas. Indeed, the cost of WiFi equipments is very affordable compared to other telecommunications equipments used for transmission over long distance such as optical fiber, WiMAX, VSAT and microwave systems.
Non-CD28 Costimulatory Molecules Present in T Cell Rafts Induce T Cell Costimulation by Enhancing the Association of TCR with Rafts1

While CD28 functions as the major T cell costimulatory receptor, a number of other T cell molecules have also been described to induce T cell costimulation. Here, we investigated the mechanisms by which costimulatory molecules other than CD28 contribute to T cell activation. Non-CD28 costimulatory molecules such as CD5, CD9, CD2, and CD44 were present in the detergent-insoluble glycolipid-enriched (DIG) fraction/raft of the T cell surface, which is rich in TCR signaling molecules and generates a TCR signal upon recruitment of the TCR complex. Compared with CD3 ligation, coligation of CD3 and CD5 as an example of DIG-resident costimulatory molecules led to an enhanced association of CD3 and DIG. Such a DIG redistribution markedly up-regulated TCR signaling as observed by ZAP-70/LAT activation and Ca2+ influx. Disruption of DIG structure using an agent capable of altering cholesterol organization potently diminished Ca2+ mobilization induced by the coligation of CD3 and CD5. This was associated with the inhibition of the redistribution of DIG although the association of CD3 and CD5 was not affected. Thus, the DIG-resident costimulatory molecules exert their costimulatory effects by contributing to an enhanced association of TCR/CD3 and DIG.
Constitutional FLCN mutations in patients with suspected Birt–Hogg–Dubé syndrome ascertained for non‐cutaneous manifestations

Maffé A, Toschi B, Circo G, Giachino D, Giglio S, Rizzo A, Carloni A, Poletti V, Tomassetti S, Ginardi C, Ungari S, Genuardi M. Constitutional FLCN mutations in patients with suspected Birt–Hogg–Dubé syndrome ascertained for non‐cutaneous manifestations.
G-s0 mode converter for nano plasmonic integrated circuits

A waveguide-typed plasmonic mode-size converter (WPMC) is presented at a wavelength of 1.55 μm. The WPMC is composed of an insulator-metal-insulator-metal-insulator waveguide (IMIMI-W), a laterally tapered IMIMI-W and a MIM-W with lateral gold mirrors in series. The input Ss<sub>0</sub> mode with the size of 5.9 μm × 4.8 μm is converted to the output gap-s<sub>0</sub> (G-s<sub>0</sub>) mode with the size of ~1.1 μm × 0.5 μm. The total loss for the G-s<sub>0</sub> mode converter is ~6.96 dB.
Indications, results, and clinical impact of endoscopic ultrasound (EUS)-guided sampling in gastroenterology: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline

This article is part of a combined publication that expresses the current view of the European Society of Gastrointestinal Endoscopy (ESGE) about endoscopic ultrasound (EUS)-guided sampling in gastroenterology, including EUS-guided fine needle aspiration (EUS-FNA) and EUS-guided trucut biopsy (EUS-TCB), of submucosal tumors, diffuse esophageal/gastric wall thickening, pancreatic solid masses and cystic-appearing lesions, mediastinal lesions unrelated to lung or esophageal cancer, cancer of the esophagus, stomach, and rectum, lymph nodes of unknown origin, adrenal gland masses, and focal liver lesions. False-positive cytopathological results and needle tract seeding are also discussed. The present Clinical Guideline describes the results of EUS-guided sampling in the different clinical settings, considers the role of this technique in patient management, and makes recommendations on circumstances that warrant its use. A two-page executive summary of evidence statements and recommendations is provided. A separate Technical Guideline describes the general technique of EUS-guided sampling, particular techniques to maximize the diagnostic yield depending on the nature of the target lesion, and sample processing. The target readership for the Clinical Guideline mostly includes gastroenterologists, oncologists, internists, and surgeons while the Technical Guideline should be most useful to endoscopists who perform EUS-guided sampling.
Technical note: how to use Winbugs to draw inferences in animal models.

This paper deals with Bayesian inferences of animal models using Gibbs sampling. First, we suggest a general and efficient method for updating additive genetic effects, in which the computational cost is independent of the pedigree depth and increases linearly only with the size of the pedigree. Second, we show how this approach can be used to draw inferences from a wide range of animal models using the computer package Winbugs. Finally, we illustrate the approach in a simulation study, in which the data are generated and analyzed using Winbugs according to a linear model with i.i. d errors having Student's t distributions. In conclusion, Winbugs can be used to make inferences in small-sized, quantitative, genetic data sets applying a wide range of animal models that are not yet standard in the animal breeding literature.
Barriers To Fostering Student Success In High-Poverty, High-Minority, High-Achieving Rural Schools

In this article we present the challenges facing high achieving, high poverty, and high minority rural schools in Alabama. This is part one of a three part exploratory, qualitative, multi-case study, and it differs from most studies on the topic of overcoming the achievement gap in that the focus was on the perceptions of key stakeholders and not the programs, policies, curriculum, or leadership styles. We identified three major recurring perceptions of the challenges facing the participant schools centered on three themes: student-centered issues, school-level challenges, and limited community support. One of the interesting aspects of this research is that a number of the issues identified as barriers to school success, particularly in rural school districts, were not identified in previous research. This article provides a window into the challenges these high-poverty, high-minority, and high-achieving rural schools in Alabama face in their quest to close the existing achievement gap to ensure their students have the tools necessary to be successful both in school and as productive adults after they graduate.
A 2D and 3D Indoor Mapping Approach for Virtual Navigation Services

Specific navigation systems are necessary to navigate in complex buildings and these should provide a realistic virtual indoor environment. A key issue is creation and management of building documentation. Map information is typically proprietary, sometimes recorded on heterogeneous media, and it is even volatile, such as layouts in a shopping mall, where change is continuous. In order to create a navigation system with a realistic indoor virtual environment, we propose a 2D and 3D indoor mapping approach, which is a key module of indoor services life cycle. Our approach is based on a 3D game engine, which 1) can build an effective 2D SVG map that updates selectively, 2) converts it into a 3D virtual scene automatically at back-end, 3) includes an information management system at back-end, 4) renders and interacts efficiently and effectively on a smart phone, and 5) provides a vivid virtual indoor visualization for users' navigation at front-end. Our solution of back-end includes 2D SVG indoor map management and 3D indoor model creation. Front-end includes indoor 3D modeling and navigation scene implementation in Unity3D. Such indoor mapping approach provides a solid foundation for further indoor management and navigation services.
Professional practice competencies in a Work-Integrated Learning course

Work Integrated Learning (WIL) programs provide students with the opportunity to develop `work-ready' skills as part of their undergraduate engineering education. The critical reflection of professional competencies is an important part of many WIL curricula. This paper describes an anonymous survey questionnaire of engineering teaching staff who marked a structured professional practice report within an engineering WIL course, to investigate their perceptions of the assessment of professional practice competencies. The study has identified the importance of these competencies and the style and structure of the report plus appropriate on-line resources have helped markers in their identification.
Investigation of the Source of Snoring Sound by Drug-Induced Sleep Nasendoscopy

Objective: To investigate the source of snoring sound in patients with simple snoring (SS) and different degrees of obstructive sleep apnea syndrome (OSAS) in order to provide a basis for the surgical treatment of snoring. Methods: Fifty-two patients with either SS or OSAS (with an apnea-hypopnea index ≤40) underwent drug-induced sleep nasendoscopy (DISN). Vibration sites in the pharyngeal cavity were observed. Results: Vibration of the soft palate, pharyngeal lateral wall, epiglottis, and tongue base appeared in 100, 53.8, 42.3, and 26.9% of the patients, respectively. The source of snoring sound was divided into two types: palatal fluttering only (type I) and multisite vibration (type II). The latter was divided into 3 subtypes: palatal fluttering with epiglottis vibration (type IIa), palatal fluttering with lateral wall vibration (type IIb), and palatal fluttering with vibration of the lateral wall, epiglottis, and tongue base together (type IIc). The distribution of type I snoring was the highest in SS patients. Type IIb was more common in patients with medium and severe OSAS. Type IIc was most common in patients with severe OSAS. Conclusion: The source of snoring sound is diverse, with SS and OSAS patients showing different features. DISN is a very effective method of identifying the snoring source.
CONATIVE ASPECT OF CIVIL IDENTITY: AN INFLUENCE OF RELIGIOUS AND CONFESSIONAL FACTORS

Religious processes play an important role in the life of human civil society. Although there are a lot of works dedicated to the study of the relationship between religion and politics, between religion and the state, far less attention has been paid to the study of the infl uence of religion on the formation of a civil society. The main purpose of this article is to study the infl uence of religion on the development of the conative (pragmatic) aspect of the civil identity of countries in Western and Eastern Europe. The author of the article has used the Index of Civil and Political Activity (ICPA) and the fi gures of declared religious identity according to the 6th round of ESS. As a result, the author has reached the following conclusions: 1) the pragmatic part of civil identity – civil practice – has been growing in most countries in Western and Eastern Europe, while the proportion of citizens identifying themselves with any religion or confession has been declining. 2) There exists a relationship between the religious affi liation and the level of civil and political activity (ICPA is higher in protestant countries)
Reconciling the Original Schumpeterian Model with the Observed Inverted-U Relationship between Competition and Innovation

Empirical studies have uncovered an inverted-U relationship between product-market competition and innovation. This is inconsistent with the original Schumpeterian Model, where greater competition reduces the profitability of innovation. We show that the model can predict the inverted-U if the innovators’ talent is heterogenous, and privately observable. With competition low and profitability high, talented innovators are credit constrained, since others are eager to mimic them. As competition increases, the mimickers become less eager, and talented innovators can invest more. This generates the increasing part of the relationship. With competition high, talented innovators are unconstrained, and the relationship is decreasing.
JAZ mediates G1 cell cycle arrest by interacting with and inhibiting E2F1

We discovered and reported JAZ as a unique dsRNA binding zinc finger protein that functions as a direct, positive regulator of p53 transcriptional activity to mediate G1 cell cycle arrest in a mechanism involving upregulation of the p53 target gene, p21. We now find that JAZ can also negatively regulate the cell cycle in a novel, p53-independent mechanism resulting from the direct interaction with E2F1, a key intermediate in regulating cell proliferation and tumor suppression. JAZ associates with E2F1’s central DNA binding/dimerization region and its C-terminal transactivation domain. Functionally, JAZ represses E2F1 transcriptional activity in association with repression of cyclin A expression and inhibition of G1/S transition. This mechanism involves JAZ-mediated inhibition of E2F1’s specific DNA binding activity. JAZ directly binds E2F1 in vitro in a dsRNA-independent manner, and JAZ’s dsRNA binding ZF domains, which are necessary for localizing JAZ to the nucleus, are required for repression of transcriptional activity in vivo. Importantly for specificity, siRNA-mediated “knockdown” of endogenous JAZ increases E2F transcriptional activity and releases cells from G1 arrest, indicating a necessary role for JAZ in this transition. Although JAZ can directly inhibit E2F1 activity independently of p53, if functional p53 is expressed, JAZ may exert a more potent inhibition of cell cycle following growth factor withdrawal. Therefore, JAZ plays a dual role in cell cycle regulation by both repressing E2F1 transcriptional activity and activating p53 to facilitate efficient growth arrest in response to cellular stress, which may potentially be exploited therapeutically for tumor growth inhibition.
Humans in the loop on subjective domains

In this project, we develop a neural network model which is capable of performing multiclass classification. This model is integrated with the active learning framework to autonomously label the incoming data; making it a loop. The efficiency of binary neural network and binary support vector machine model will be compared with this new multiclass model.
Community Empowerment As a Process: A Case Study On Beff Cattle Breeder Empowerment Trough Corporate Social Responsibility (CSR) IN PT. Perkebunan Nusantara XII, Eats Java, Indonesia

ABSTRACT The process of community empowerment can not be seen only as a means to achieve the goal, but becomes an important goal. Community empowerment is a process in itself. The empowerment process should involve the community. Stages of empowering are training, visits and assistance are quite participative, not accompanied by enabling stages (identification of potential and problems and socialization) are participatory. Full participation at the enabling stage is constrained by cost efficiency and predetermined time limits. The scope of empowerment is still based on the strengthening of economic capital by granting loans for the purchase of livestock germs and human capital with counseling and training. While the strengthening of physical capital, nature and social has not received serious attention. Institutions that are formed have not been able to unite the breeders in order to improve the livestock business more productive and efficient together. Internal CSR with facilitators from the internal company is more efficient and the company's interests can be accommodated, but lack of technical mastering of farms.
Effect of a Negative Ion Holographic Bracelet on Maximal Aerobic Performance

Abstract Sells, PD, Cavicchio, H, Everhart, B, Grass, B, Lambert, J, and Robinson, K. Effect of a negative ion holographic bracelet on maximal aerobic performance. J Strength Cond Res 28(10): 2895–2899, 2014—The purpose of this study was to investigate the effect of performance jewelry embedded with both a hologram and negative ions on maximal oxygen uptake (V[Combining Dot Above]O2max), V[Combining Dot Above]O2 at ventilatory threshold (V[Combining Dot Above]O2VT), or heart rate at ventilatory threshold (HRVT) measured through metabolic gas exchange. Eight males and 10 females (age = 26.5 ± 7.18 years) volunteered to participate in this study. Silicone bracelets with both hologram technology and negative ions were used as the “programmed” device. An identical silicone bracelet that did not contain the negative ion or hologram technology was used as the “nonprogrammed” device. A third condition in which the participants did not wear a band served as a control trial. The type of band worn during testing sessions was blinded from the participants and researchers. The order of testing was randomized. Subjects underwent 3 maximal graded exercise tests separated by 1 week. A repeated measure analysis of variance was used to test for mean differences across the 3 trials. The mean V[Combining Dot Above]O2max when wearing the programmed band (52.32 ± 4.79 ml·kg−1·min−1), when wearing the nonprogrammed band (51.47 ± 5.89), and without a band (53.32 ± 7.63 ml·kg−1·min−1) were found to be of no significant difference (p = 0.494). Assessment of the subjects HRVT under the 3 conditions (programmed, nonprogrammed, and no band) yielded no significant difference (p = 0.633). The HRVT of the above-mentioned 3 conditions were 136.06 ± 16.33, 135.00 ± 19.48, and 130.41 ± 24.39, respectively. The V[Combining Dot Above]O2VT for the programmed band (30.04 ± 6.91 ml·kg−1·min−1), nonprogrammed (30.77 ± 8.125 ml·kg−1·min−1), and no band (27.27 ± 8.66 ml·kg−1·min−1) were not significantly different (p = 0.221). The results of this study provide data that holographic and negative ion technology wristbands may have no effect on V[Combining Dot Above]O2max, V[Combining Dot Above]O2 at ventilatory threshold, or HRVT, and thus may have no positive effect on exercise endurance.
Simultaneous Cardiac and Respiratory Synchronization in Oxygen-Enhanced Magnetic Resonance Imaging of the Lung Using a Pneumotachograph for Respiratory Monitoring

Objectives:We sought to evaluate an optimized method for oxygen-enhanced magnetic resonance imaging of the lung, using electrocardiogram-trigger and a pneumotachograph for simultaneous cardiac and respiratory synchronization. Materials and Methods:Five series of IR-SSFSE images (echo time = 28.2 milliseconds; inversion time = 1200 milliseconds) were obtained in 6 volunteers during the ventilation-paradigm room-air/oxygen/room-air: series 1, respiratory-triggered; series 2, cardiac-triggered; series 3, cardiac-triggered and respiratory-synchronized using the signal of the pneumatic belt; series 4, cardiac-triggered and respiratory-synchronized using the external signal of the pneumotachograph; and series 5, not cardiac-triggered and respiratory-synchronized using the signal of the pneumotachograph. Standard deviations of the lung (SIvar) and diaphragm mismatch (DM) were measured. The relative SI change (&Dgr;SI) was computed from room-air and oxygen-enhanced images. Parametric maps were obtained from cross-correlation analysis of the ventilation paradigm. Mean correlation coefficients (cc) and the percentage of activated pixels over the lung (Act%) were calculated from these maps. All 5 parameters were compared among the 5 series (Friedman-analysis of variance, Dunn's posthoc test). Results:In series 4, DM and SIvar were significantly lower than in respiratory and cardiac-triggered series (DM = 4.7 vs. 14.3 and 18.4; SIvar = 4.9 vs. 10 and 11). In the same series cc and Act% also were significantly higher than in series 1 and 2 (cc = 0.86 vs. 0.7 and 0.6; Act% = 71.3 vs. 44.7 and 41.2). &Dgr;SI was not significantly different among all series. Conclusions:Effective respiratory and cardiac synchronization can be achieved in oxygen-enhanced magnetic resonance imaging of the lung, using a pneumotachograph for real-time targeting of end-expiration.
Harmonic stability analysis of offshore wind farm with component connection method

In this paper, an eigenvalue-based harmonic stability analysis method for offshore wind farm is proposed. Considering the internal cable connection layout, a component connection method (CCM) is adopted to divide the system into individual blocks as current controller of converters, LCL filters, collection system cable impedance, transmission cable impedance and grid impedance. By using this method, each block can be modelled independently and then be integrated into a whole state space matrix which contains sparse and diagonal matrix. Compared with the traditional state space formulation process, this method is superior in reducing the computational cost. A 4 by 4 wind turbines wind farm is selected as the study case and the proposed method is validated by comparing the results obtained from time domain simulation software — Power System Computer Aided Design (PSCAD).
The effects of natural S-equol supplementation on skin aging in postmenopausal women: a pilot randomized placebo-controlled trial

ObjectiveThe aim of this study was to investigate the effects of the natural S-equol supplement on skin aging in equol-nonproducing Japanese postmenopausal women. MethodsA randomized, double-blind, placebo-controlled trial examined the use of the natural S-equol supplement for 12 weeks in 101 postmenopausal Japanese women who were equol nonproducers. They were randomly assigned to one of three groups: placebo (n = 34), 10 mg S-equol/day (EQL10; n = 34), or 30 mg S-equol/day (EQL30; n = 33). Skin parameters of crow’s-feet wrinkles (area and depth), hydration, transepidermal water loss, and elasticity were measured at baseline and at monthly intervals during treatment. Vaginal cytology, endometrial thickness, and mammography were performed before and after treatment. Serum hormone concentrations were measured at the same time as skin parameters. ResultsThe EQL10 and EQL30 groups showed significant reductions in wrinkle area compared with the placebo group (P < 0.05). There was a significant difference in wrinkle depth between the placebo group and the EQL30 group (P < 0.05). Other skin parameters did not show significant differences after the treatment in any group. There were no abnormal results in hormone status or gynecological examinations. ConclusionsOur data suggest that natural S-equol supplementation (EQL10 and EQL30) may have a beneficial effect on crow’s-feet wrinkles in postmenopausal women without serious adverse events.
The effectiveness of a national communication campaign using religious leaders to reduce HIV-related stigma in Ghana

This article describes the effects of a national mass media and community-level stigma-reduction programme in Ghana, in which national and local religious leaders urged their congregations and the general public to have greater compassion for people living with HIV or AIDS (PLHA). Data were collected from men and women living in three regions, first in 2001 (n = 2 746) and again in 2003 (n = 2 926). Attitudes related to a punitive response to PLHA both improved over time and were positively associated with exposure to the programme's campaign, controlling for potential confounding variables. Respondents in the 2003 survey were 20% more likely than respondents in the 2001 survey to be willing to care for an HIV-infected relative in their own household and 40% more likely to believe that an HIV-infected female teacher should be allowed to continue teaching. Overall, respondents exposed to the campaign were 45% more likely than those not exposed to it to be willing to care for a HIV-infected relative, and 43% more likely to believe that an HIV-infected female teacher should be allowed to continue teaching. Respondents exposed to the campaign also had significantly more favourable scores on an attitude scale measuring the belief that HIV-infected individuals should be isolated from others. The results of this evaluation suggest that mass media channels and religious leaders can effectively address HIV-related stigma on a national scale.