Miracle-dz/UniFAR-FTUs huggingface dataset:
Video archiving and sign language indexation within the AMIS platform

This paper proposes a MPEG-7 compliant multimedia indexing system. The so-called AMIS (Automated Multimedia Indexing System), developed using Java technology, includes a complete chain of data and metadata processing (annotation, description management and search engine), with an user-friendly interface and support for an extended set of multimedia content types (still images, audio, videos, 3D data) represented within various formats. The system adopts the MPEG-7 approach for structural descriptions of AV content, and implements generic and dedicated media segments and recursive decomposition tools, taking full advantage of the MPEG-7 interoperable multigranular and hierarchical descriptions.
MONITORING THE GLOBAL OCEAN MESOSCALE WITH A GLOBAL OCEAN FORECASTING SYSTEM AT 1 / 12 °

(1) CERFACS, 42 av. G. Coriolis, 31057 Toulouse (France ), Email:btranchant@mercator-ocean.fr, rbourdal@mercator-ocean.fr,cderval@mercator-ocean.f r (2) CLS, 8-10, rue Hermès, Parc Technologique du Canal, 31520 Ramonville Saint-Agne (France), Email:egreiner@mercator-ocean.fr, (3) Mercator-Océan, 8-10, rue Hermès, Parc Technologiqu e d Canal, 31520 Ramonville Saint-Agne (France), Email:ctestut@mercator-ocean.fr
Bridging the Gap between Glycosylation and Vesicle Traffic

Glycosylation is recognized as a vitally important posttranslational modification. The structure of glycans that decorate proteins and lipids is largely dictated by biosynthetic reactions occurring in the Golgi apparatus. This biosynthesis relies on the relative distribution of glycosyltransferases and glycosidases, which is maintained by retrograde vesicle traffic between Golgi cisternae. Tethering of vesicles at the Golgi apparatus prior to fusion is regulated by Rab GTPases, coiled-coil tethers termed golgins and the multisubunit tethering complex known as the conserved oligomeric Golgi (COG) complex. In this review we discuss the mechanisms involved in vesicle tethering at the Golgi apparatus and highlight the importance of tethering in the context of glycan biosynthesis and a set of diseases known as congenital disorders of glycosylation.
A Deep Neural Network for Chinese Zero Pronoun Resolution

Existing approaches for Chinese zero pronoun resolution overlook semantic information. This is because zero pronouns have no descriptive information, which results in difficulty in explicitly capturing their semantic similarities with antecedents. Moreover, when dealing with candidate antecedents, traditional systems simply take advantage of the local information of a single candidate antecedent while failing to consider the underlying information provided by the other candidates from a global perspective. To address these weaknesses, we propose a novel zero pronoun-specific neural network, which is capable of representing zero pronouns by utilizing the contextual information at the semantic level. In addition, when dealing with candidate antecedents, a two-level candidate encoder is employed to explicitly capture both the local and global information of candidate antecedents. We conduct experiments on the Chinese portion of the OntoNotes 5.0 corpus. Experimental results show that our approach substantially outperforms the state-of-the-art method in various experimental settings.
Simple Camera Calibration From a Single Image Using Five Points on Two Orthogonal 1-D Objects

We propose a simple and practical calibration technique that effectively estimates camera parameters from just five points on two orthogonal 1-D objects, each which has three collinear points, one of which is shared. We derive the basic equations needed to realize camera calibration from just five points observed on a single image that captures the objects. We describe a new camera calibration algorithm that estimates the camera parameters based on the basic equations and optimizes them by the bundle adjustment technique. Our method is validated by both computer simulated data and real images. The results show that the camera parameters yielded by our method are close to those yielded by existing methods. The tests demonstrate that our method is both effective and practical.
Role of Caffeine Intake on Erectile Dysfunction in US Men: Results from NHANES 2001-2004

Objectives Caffeine is consumed by more than 85% of adults and little is known about its role on erectile dysfunction (ED) in population-based studies. We investigated the association of caffeine intake and caffeinated beverages with ED, and whether these associations vary among comorbidities for ED. Material and Method Data were analyzed for 3724 men (≥20 years old) who participated in the National Health and Nutrition Examination Survey (NHANES). ED was assessed by a single question during a self-paced, computer-assisted self-interview. We analyzed 24-h dietary recall data to estimate caffeine intake (mg/day). Multivariable logistic regression analyses using appropriate sampling weights were conducted. Results We found that men in the 3rd (85-170 mg/day) and 4th (171-303 mg/day) quintiles of caffeine intake were less likely to report ED compared to men in the lowest 1st quintile (0-7 mg/day) [OR: 0.58; 95% CI, 0.37–0.89; and OR: 0.61; 95% CI, 0.38–0.97, respectively], but no evidence for a trend. Similarly, among overweight/obese and hypertensive men, there was an inverse association between higher quintiles of caffeine intake and ED compared to men in the lowest 1st quintile, P≤0.05 for each quintile. However, only among men without diabetes we found a similar inverse association (Ptrend = 0.01). Conclusion Caffeine intake reduced the odds of prevalent ED, especially an intake equivalent to approximately 2-3 daily cups of coffee (170-375 mg/day). This reduction was also observed among overweight/obese and hypertensive, but not among diabetic men. Yet, these associations are warranted to be investigated in prospective studies.
Reading recognition method of analog measuring instruments based on improved hough transform

To effectively resolve the automatic recognition problem of analog measuring instruments, a reading recognition method based on improved Hough transformation is proposed. Firstly, the paper presents the image preprocessing operation. In order to make the image filtering better, an improved adaptive median filter method is adopted. Secondly, we explains in detail the recognition principle for the pointer angle using the improved Hough transform. And the pointer's reading is got using the linear relationship between scale and angle of instrument dial revolutionary. In order to further improve the recognition accuracy, as to the situation that pointer completely coincides with the whole tick, late correction will be done. Finally, the automatic recognition software is written in VC++6.0 IDE, and complete the recognition experiment for the AC voltmeter. The experimental results show that the method is very valid for the pointer angle recognition. In addition, the advantages of this study are as following: simple algorithm, good real-time and high precision.
Prospective Associations Between Intervention Components and Website Engagement in a Publicly Available Physical Activity Website: The Case of 10,000 Steps Australia

Background Effectiveness of and engagement with website-delivered physical activity interventions is moderate at best. Increased exposure to Internet interventions is reported to increase their effectiveness; however, there is a lack of knowledge about which specific intervention elements are able to maintain website engagement. Objective To prospectively study the associations of website engagement and exposure to intervention components for a publicly available physical activity website (10,000 Steps Australia). Methods Between June and July 2006 a total of 348 members of 10,000 Steps completed a Web-based survey to collect demographic characteristics. Website engagement was subsequently assessed over a 2-year period and included engagement data on website components; individual challenges, team challenges, and virtual walking buddies; and indicators of website engagement (average steps logged, days logging steps, and active users). Results On average participants logged steps on 169 (SD 228.25) days. Over a 2-year period this equated to an average of 1.6 logons per week. Binary logistic regression showed that individuals who participated in individual challenges were more likely to achieve an average of 10,000 steps per day (odds ratio [OR] = 2.80, 95% confidence interval [CI] 1.45–5.40), log steps on a higher than average number of days (OR = 6.81, 95% CI 2.87–13.31), and remain an active user (OR = 4.36, 95% CI 2.17–8.71). Additionally, those using virtual walking buddies (OR = 5.83, 95% CI 1.27–26.80) and of older age logged steps on a higher than average number of days. No significant associations were found for team challenges. Conclusions Overall engagement with the 10,000 Steps website was high, and the results demonstrate the relative effectiveness of interactive components to enhance website engagement. However, only exposure to the interactive individual challenge feature was positively associated with all website engagement indicators. More research is needed to examine the influence of intervention components on website engagement, as well as the relationship between website engagement and physical activity change.
Proton MRS reveals frontal lobe metabolite abnormalities in idiopathic generalized epilepsy

Objective: To assess γ-aminobutyric acid (GABA) plus homocarnosine (GABA+) and glutamate plus glutamine (GLX) concentrations in the frontal lobes of patients with idiopathic generalized epilepsy (IGE). Methods: Twenty-one patients and 17 healthy volunteers were studied. A single voxel was prescribed in each frontal lobe for each subject. Point-resolved spectroscopy (PRESS)-localized short echo time MR spectroscopy (MRS) was performed to measure GLX and the metabolites N-acetylaspartate plus N-acetylaspartylglutamate (NAAt), creatine and phosphocreatine (Cr), choline-containing compounds (Cho), and myo-inositol (Ins). A double quantum GABA filter was used to measure GABA+. Segmented T1-weighted images gave the tissue composition of the prescribed voxel. Results: Group comparisons showed elevation of GLX and reduction of NAAt in the patient group (p < 0.05). The metabolite ratios GLX/NAAt and GLX/Ins also showed elevation in IGE (p = 0.01). No group effect was observed for GABA+, Cr, or Cho. Ins concentrations were not significantly reduced in the patient group but were less in the subgroup of patients who were taking sodium valproate. Conclusions: IGE was associated with bilateral frontal lobe metabolite changes. Elevation in GLX was observed, which may imply increased neuronal excitability, whereas reduction in NAAt suggests reduced overall neuronal numbers or neuronal dysfunction.
A review of PTSD and shame in military veterans

ABSTRACT Traumatic military experiences can create ethical dilemmas that result in moral injury. Moral injury is strongly correlated with interpersonal problems, social anxiety, isolation, depression, and suicide. Shame, considered the primary component of moral injury, amplifies the impact of trauma across every category. Shame relates to the trauma experience and is fortified by poor homecomings and the years following veterans’ return from battle. Self-criticism acts as a barrier to care and existing assessment and treatment procedures may require modification in order to be fully effective for treating moral injury.
Covalent binding of moxalactam to cephalosporinase of Citrobacter freundii

The inhibition of Citrobacter freundii cephalosporinase activity by moxalactam is shown to be due to the formation of a transiently stable covalent complex, probably acyl enzyme. The covalent complex formed was identified by coelution of [14C] moxalactam with the enzyme by using Sephadex G-25 gel filtration in the presence of 5.7 M guanidine hydrochloride and by analytical isoelectric focusing. Both the side-chain carboxyl group and the 7 alpha-methoxy group of moxalactam were necessary to stabilize the complex. Moxalactam is racemic with respect to the alpha carbon of the 7 beta-acylamino side chain, and the complex with the R epimer (half-life, 4.6 min) decomposed much more rapidly than that formed with the S epimer (half-life, 130 min). For other beta-lactam antibiotics that were stable to beta-lactamase, the half-lives of enzyme-antibiotic complexes were less than 4 min.
Time-dependent bending rigidity and helical twist of DNA by rearrangement of bound HU protein

HU is a protein that plays a role in various bacterial processes including compaction, transcription and replication of the genome. Here, we use atomic force microscopy to study the effect of HU on the stiffness and supercoiling of double-stranded DNA. First, we measured the persistence length, height profile, contour length and bending angle distribution of the DNA–HU complex after different incubation times of HU with linear DNA. We found that the persistence and contour length depend on the incubation time. At high concentrations of HU, DNA molecules first become stiff with a larger value of the persistence length. The persistence length then decreases over time and the molecules regain the flexibility of bare DNA after ∼2 h. Concurrently, the contour length shows a slight increase. Second, we measured the change in topology of closed circular relaxed DNA following binding of HU. Here, we observed that HU induces supercoiling over a similar time span as the measured change in persistence length. Our observations can be rationalized in terms of the formation of a nucleoprotein filament followed by a structural rearrangement of the bound HU on DNA. The rearrangement results in a change in topology, an increase in bending flexibility and an increase in contour length through a decrease in helical pitch of the duplex.
Risk-Taking Behavior and Suicidality: The Unique Role of Adolescent Drug Use

Research has supported an association between suicidal thoughts/behaviors and risk taking, which may be particularly strong during adolescence when risk taking is known to increase. However, extant research has focused on individual risk-taking behaviors (e.g., alcohol use), limiting our ability to evaluate the unique association between different risk-taking behaviors and suicidal thoughts/behaviors. The current study aimed to fill this gap by examining the simultaneous influence of multiple risk-taking behaviors (i.e., risky sexual behavior, tobacco/alcohol use, illicit drug use, delinquent behavior, violent behavior) on adolescent suicidal thoughts/behaviors. Data from the National Longitudinal Study of Adolescent Health was utilized. The sample consisted of 4,834 adolescents who completed home interviews at two time points. At the first time point, participants’ mean age was 15.15, with 48% (n = 2,315) identifying as male. Participants provided information about suicidal thoughts/behaviors and multiple risk-taking behaviors at an initial interview and at a second interview, approximately 11 months later. When independently examined, nearly all assessed risk-taking behaviors were independently associated with suicidal ideation concurrently and prospectively, and with suicide attempts concurrently. When all risk-taking behaviors were examined simultaneously, illicit drug use was the only significant concurrent and significant prospective, albeit negative, predictor of suicidal thoughts and only concurrent predictor of suicidal behavior. The current findings suggest that illicit drug use may have a stronger association with suicidal thoughts and behaviors than other risk-taking behavior. These findings have implications for prevention and intervention programs for adolescents.
Early recognition of Internet service flow

Early service flow recognition is required in both network management and intrusion detection systems. However, there exists some deficiency in existing machine learning methods when used in time or accuracy critical conditions. We put forward an early recognition method of Internet service flow and verify it by multiple experiment sets. As simulation results show, based on the packet lengths and the packet intervals of the first N packets, the method, utilizing improved k nearest neighbors (KNN) algorithm, can effectively identify the unknown service flow in the network.
Predicting the performance of globus monitoring and discovery service (MDS-2) queries

Resource discovery and monitoring in a distributed grid environment gives rise to several issues, one of which is the provision of reliable performance and hence, the quality-of-service delivered to grid users. This performance requirement brings about the necessity to know how the monitoring and discovery service (MDS) would respond to various queries. We focus on the performance of the MDS as part of the knowledge needed by a grid entity, to choose a grid index information service (GIIS) for discovering resources. Several performance metrics are defined and the performance achieved by a GIIS is evaluated against that obtained by a GRIS [H.N. Lim Choi Keung et al. (2003)]. Based on the GIIS performance data collected, the values for the performance metrics are predicted using different algorithms. Thus, past performance observations can be used to qualitatively characterise the future performance of the GIIS, allowing grid middleware built on these services to be more predictable.
Voltage-dependent Ca2+ channels, not ryanodine receptors, activate Ca2+-dependent BK potassium channels in human retinal pigment epithelial cells

Purpose In different tissues the activation of large conductance Ca2+-activated (BK) potassium channels has been shown to be coupled to voltage-gated Ca2+ channels as well as ryanodine receptors. As activation of BK channels leads to hyperpolarization of the cell, these channels provide a negative feedback mechanism for Ca2+-induced functions. Many cellular functions of the retinal pigment epithelium (RPE) are coupled to changes in [Ca2+]i. The aim of this study was to identify which Ca2+-entry pathway leads to the activation of BK channels in the RPE. Methods We used freshly isolated human RPE cells and the ARPE-19 cell line for the detection of transcripts of BK channel α subunits. Patch-Clamp measurements were used to characterize BK channels in ARPE-19 cells electrophysiologically. To monitor changes in [Ca2+]i ARPE-19 cells were loaded with Fura-2. Results Freshly isolated human RPE cells and ARPE-19 cells were shown to express BK channels. In ARPE-19 cells these channels were shown to be functionally active. Application of iberiotoxin led to a block of outward currents by 28.15%. At +50 mV ARPE-19 cells had a BK channel-mediated current density of 2.42 pA/pF. Activation of ryanodine receptors by caffeine led to a significant increase in [Ca2+]i by 34.16%. Nevertheless, caffeine-induced Ca2+ signals were not sufficient to activate BK channels. Instead, the activation of L-type Ca2+ channels by BayK 8644 caused a dramatic increase in BK channel activity and a shift of the reversal potential of the ARPE-19 cells by −22.6 mV. Conclusions We have shown here for the first time that human RPE cells express BK channels. These channels are activated in RPE cells by increases in [Ca2+]i that are mediated by the opening of voltage gated L-type Ca2+ channels. As Ca2+ entering the RPE cells through these Ca2+ channels are known to be important for growth factor secretion and light-induced transepithelial transport, we speculate that BK channels coupled directly to these Ca2+ channels may provide a good tool for negative feedback control of the L-type Ca2+ channels.
The I-search paper

This revised and retitled edition of "Searching Writing" includes two additional I-Search papers, one by a teacher, and a new chapter entitled "The Larger Context," which shows how the I Search concept can work throughout the whole curriculum in school and college. As with the first edition, The "I-Search Paper" is more than just a textbook; it's a new form of instructional help -- a "context "book -- that shows students what authority is in matters of learning and invites them to join the author and teacher in the educational movement called "Writing to Learn. " To put this book in the hands of all the students in the course is not only to help them carry out an I-Search but to introduce them in a delightful way to the resources and tools of intellectual inquiry -- but one that never forgets the emotional or physical side of human activity. This is a rare textbook that treats students as partners in learning. It shows what it is to take charge of one's own learning and suggests that this move is one that productive people keep making throughout their lives.
Energy, saturated fat and fibre intakes among Dutch children and adolescents at breakfast and implications for educational messages

The aim of this study was to assess energy, saturated fat and fibre intakes at breakfast among Dutch youngsters aged 10–19 years and the extent to which they meet nutritional value recommendations and the educational messages on food group intake by the Netherlands Nutrition Centre (NNC). A cross-sectional design was used and data were collected through an online questionnaire among 2380 students attending 71 Dutch schools for primary and secondary education. Energy intake at breakfast was, on average, 15.8% of daily recommended energy intake; mean saturated fat intake was 7.5 en% and mean fibre intake 1.0 g per 100 kcal. Of the participants, 67.2% met the saturated fat intake recommendation and 35.3% the fibre intake recommendation. In addition, 25.5% were assessed to have an adequate energy intake based on daily recommended, but not individually measured, age- and gender-specific energy intake. Most participants consumed products from the grains food group, in combination with products from one or two other food groups. Consumption from two or more food groups resulted in less favourable intake. Our study found generally inadequate fibre intake at breakfast as well as an indication of inadequate energy intake at breakfast among Dutch youngsters. The educational message of the NNC to consume at least (wholemeal) bread or another fibre-rich product (cereals) at breakfast seems realistic in terms of compliance and favourable in terms of the resulting nutritional value. The educational message to preferably eat from each of the five main food groups should be reconsidered.
A GIS Web with integration of sheet and soil databases of the Brazilian Cerrado

New challenges for the management of environmental data require interoperability, integration and the sharing of data. This article presents a SIG Web based on service oriented architecture for the integration of data bases related to data on soil and sheet collected in the Brazilian biomass. In the architecture proposed for the development of the SIG, the concept of ontology was used to support the problem of semantic heterogeneity in distinct databases.