Miracle-dz/UniFAR-FTUs huggingface dataset:
Large Scale Data Mining for IT Service Management

OF THE DISSERTATION LARGE SCALE DATA MINING FOR IT SERVICE MANAGEMENT by Chunqiu Zeng Florida International University, 2016 Miami, Florida Professor Tao Li, Co-Major Professor Professor Shu-Ching Chen, Co-Major Professor More than ever, businesses heavily rely on IT service delivery to meet their current and frequently changing business requirements. Optimizing the quality of service delivery improves customer satisfaction and continues to be a critical driver for business growth. The routine maintenance procedure plays a key function in IT service management, which typically involves problem detection, determination and resolution for the service infrastructure. Many IT Service Providers adopt partial automation for incident diagnosis and resolution where the operation of the system administrators and automation operation are intertwined. Often the system administrators’ roles are limited to helping triage tickets to the processing teams for problem resolving. The processing teams are responsible to perform a complex root cause analysis, providing the system statistics, event and ticket data. A large scale of system statistics, event and ticket data aggravate the burden of problem diagnosis on both the system administrators and the processing teams during routine maintenance procedures. Alleviating human efforts involved in IT service management dictates intelligent and efficient solutions to maximize the automation of routine maintenance procedures. Three research directions are identified and considered to be helpful for IT service management optimization: (1) Automatically determine problem categories
Yeast Cells Lacking the Mitochondrial Gene Encoding the ATP Synthase Subunit 6 Exhibit a Selective Loss of Complex IV and Unusual Mitochondrial Morphology*

Atp6p is an essential subunit of the ATP synthase proton translocating domain, which is encoded by the mitochondrial DNA (mtDNA) in yeast. We have replaced the coding sequence of Atp6p gene with the non-respiratory genetic marker ARG8m. Due to the presence of ARG8m, accumulation of ρ–/ρ0 petites issued from large deletions in mtDNA could be restricted to 20–30% by growing the atp6 mutant in media lacking arginine. This moderate mtDNA instability created favorable conditions to investigate the consequences of a specific lack in Atp6p. Interestingly, in addition to the expected loss of ATP synthase activity, the cytochrome c oxidase respiratory enzyme steady-state level was found to be extremely low (<5%) in the atp6 mutant. We show that the cytochrome c oxidase-poor accumulation was caused by a failure in the synthesis of one of its mtDNA-encoded subunits, Cox1p, indicating that, in yeast mitochondria, Cox1p synthesis is a key target for cytochrome c oxidase abundance regulation in relation to the ATP synthase activity. We provide direct evidence showing that in the absence of Atp6p the remaining subunits of the ATP synthase can still assemble. Mitochondrial cristae were detected in the atp6 mutant, showing that neither Atp6p nor the ATP synthase activity is critical for their formation. However, the atp6 mutant exhibited unusual mitochondrial structure and distribution anomalies, presumably caused by a strong delay in inner membrane fusion.
A generalization of the maximum a posteriori training algorithm for mixture priors

Prior information about the operating environment of a speech recognizer is often general and abstract. Frequently information such as the number of speakers with foreign accents or the number of callers using cellular phones is readily available. Incorporating this information during model training is difficult. This paper generalizes the popular MAP training algorithm derived by Gauvain and Lee (1994) so that more prior information can be utilized during training. The priors are in the form of mixture distributions with each mixture component representing a unique property of the data and the mixing weights defined by the a priori constraints. Using the training algorithms derived here it is shown that significant performance improvements can be obtained.
Horizontal Maxillary Osteotomy With Interpositional Fibula Flap

Horizontal maxillary osteotomy with an interpositional fibula flap for maxillary deficiency offers several advantages over conventional techniques for maxillary reconstruction. Maxillary deficiencies in all 3 planes, vertical, anterior-posterior, and transverse, can be corrected with a long-term stable construct while simultaneously restoring bony and soft tissue deficiencies. We conducted a retrospective review of patients with maxillary hypoplasia who underwent Horizontal maxillary osteotomy with interpositional osteoseptocutaneous fibula flaps. Compared with nonvascularized bone grafts, vascularized bone flaps undergo less resorption and can be used in poorly vascularized, mechanically unstable, irradiated, or scarred wound beds.
Setdb1 is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cells

Transcription of endogenous retroviruses is inhibited by de novo DNA methylation during gametogenesis, and DNA methylation reaches a low point in E13.5 primordial germ cells (PGCs) of both sexes. Liu et al. find that germline-specific conditional knockout of the H3K9 methyltransferase SETDB1 yields a decrease of H3K9me3 and H3K27me3 marks and DNA methylation at H3K9me3-enriched retrotransposon families. Setdb1 deficiency is associated with a reduced number of male E13.5 PGCs and postnatal hypogonadism in both sexes. Therefore, SETDB1 is an essential guardian against proviral expression prior to the onset of de novo DNA methylation in the germline.
Crystal structure of human grancalcin, a member of the penta-EF-hand protein family.

Grancalcin is a Ca(2+)-binding protein expressed at high level in neutrophils. It belongs to the PEF family, proteins containing five EF-hand motifs and which are known to associate with membranes in Ca(2+)-dependent manner. Prototypic members of this family are Ca(2+)-binding domains of calpain. Our recent finding that grancalcin interacts with L-plastin, a protein known to have actin bundling activity, suggests that grancalcin may play a role in regulation of adherence and migration of neutrophils. The structure of human grancalcin has been determined at 1.9 A resolution in the absence of calcium (R-factor of 0.212 and R-free of 0.249) and at 2. 5 A resolution in the presence of calcium (R-factor of 0.226 and R-free of 0.281). The molecule is predominantly alpha-helical: it contains eight alpha-helices and only two short stretches of two-stranded beta-sheets between the loops of paired EF-hands. Grancalcin forms dimers through the association of the unpaired EF5 hands in a manner similar to that observed in calpain, confirming this mode of association as a paradigm for the PEF family. Only one Ca(2+) was found per dimer under crystallization conditions that included CaCl(2). This cation binds to EF3 in one molecule, while this site in the second molecule of the dimer is unoccupied. This unoccupied site shows higher mobility. The structure determined in the presence of calcium, although does not represent a fully Ca(2+)-loaded form, suggests that calcium induces rather small conformational rearrangements. Comparison with calpain suggests further that the relatively small magnitude of conformational changes invoked by calcium alone may be a characteristic feature of the PEF family. Moreover, the largest differences are localized to the EF1, thus supporting the notion that calcium signaling occurs through this portion of the molecule and that it may involve the N-terminal Gly/Pro rich segment. Electrostatic potential distribution shows significant differences between grancalcin and calpain domain VI demonstrating their distinct character.
Structural and contractile properties of lobster leg-muscle fibers.

Three leg muscles of the American lobster, namely, the extensor muscle of the carpopodite in the walking legs, the closer muscle of the “cutter” claw, and the closer muscle of the “crusher” claw, were examined to see what types of muscle fiber they contain. In all three muscles, slow and fast fibers, as well as intermediate types, were present. Contraction rates of both types increased with the amplitude of the applied depolarization; slow fibers showed more lability in this respect, but they did not contract as rapidly as the fast fibers even when strongly stimulated. Membrane potential threshold for contraction was positively correlated with resting membrane potential in both types of fiber. Slow fibers differed from fast fibers structurally in having longer sarcomeres and A-bands, smaller numbers of diads per unit length of muscle fiber, larger thin:thick filament ratios, and more connective tissue and sarcolemmal elements. The two claw closer muscles differed markedly in their proportions of slow and fast fibers, the “cutter” claw having a preponderance of short-sarcomere, fast fibers. This finding helps to explain the difference in contraction speed of these two claw muscles.
Interfaces with Other Disciplines Mismanagement or mismeasurement? Pitfalls and protocols for DEA studies in the financial services sector

Dyson et al. [Dyson, R.G. , Allen, R. , Camanho, A.S. , Podinovski, V.V. , Sarrico, C.S. , Shale, E.A. , 2001. Pitfalls and protocols in DEA. European Journal of Operational Research 132, 245–259] suggest that the application of DEA presents a range of problems and they suggest that the systematic collection and reporting of these problems would significantly enhance DEA practice. It is widely accepted that DEA studies may be compromised by the problem of data heterogeneity. While this problem is expected in studies that cross national boundaries, it may also arise in studies for a single country. There can, for example, be significant market and regulatory differences between regions within a single country. Using a sample of Australian credit unions, this paper demonstrates the pitfalls and protocols of using DEA. It is intended that the guidelines provided in this study will enhance DEA practice in the financial services sector. � 2005 Elsevier B.V. All rights reserved.
Enhancing market access of demand response through generation forecast updates

Advances in communication infrastructure and electric appliances have enabled demand side participation in power system operation. However, the full potential of demand flexibility is yet to be exploited. Existing demand response programs require flexibility in a set time frame from the electricity consumers in reaction to economic incentives. For a more detailed qualitative analysis of consumer flexibility, not only price but also notice time are imperative parameters. The former has been studied in numerous references whereas the impact of the latter has not yet been examined in depth. This paper presents a market model of demand response that enhances an efficient use of flexible consumers by hourly updates. The consequences of flexible electricity consumers are studied in a Real Time Pricing model with continuous forecast updates, where elasticity is subject to notice time. A case study is presented using data from Sweden. We conclude that current demand response programs are not optimally designed to integrate consumer flexibility that changes with the notice time.
Age-dependent prognostic value of exercise capacity and derivation of fitness-associated biologic age

Objective Given the aging population and prevalence of sedentary behaviour in the USA, we investigated the impact of differences in exercise capacity associated with age on long-term outcomes. We derived fitness-associated ‘biologic age’ as a tool to encourage positive lifestyle changes. Methods This retrospective cohort study included 57 085 patients without established coronary artery disease or heart failure (median age 53 years, 49% women, 29% black) who underwent clinically-referred treadmill stress testing at the Henry Ford Health System from 1991 to 2009. Patients were followed for 10.4±5 and 5.4±4 years for all-cause mortality and myocardial infarction (MI), respectively. We calculated hazard ratios associated with exercise capacity by age deciles using Cox regression models, adjusting for demographic and haemodynamic data, medical history, and medication use. Fitness-associated ‘biologic age’ was derived as the chronologic age with equivalent mortality or MI risk. Results There were 6356 deaths and 1646 MIs during follow-up. Exercise capacity declined with increasing age. Higher exercise capacity was strongly associated with greater survival, with per-MET HR ranging from 0.82 (95% CI 0.78 to 0.86) in patients under 40 years of age, to 0.88 (95% CI 0.87 to 0.90) in those over 70 years of age. Biologic age varied markedly—up to three decades—within each age decile, and was a stronger predictor of mortality (C-statistic 0.81 vs 0.77) and MI (C-statistic 0.72 vs 0.68) than chronologic age. Conclusions Higher exercise capacity remained a powerful predictor of survival despite lower average exercise capacity at older ages, reinforcing its importance in patients of all ages. Fitness-associated biologic age was a stronger predictor of survival than chronologic age, and may be a useful clinical tool for facilitating patient discussions regarding the impact of exercise capacity on long-term risk.
Methyl 2-benzyl-4-hydroxy-1,1-dioxo-1,2,3,4-tetrahydro-1λ6,2-benzothiazine-3-carboxylate

In the title compound, C17H15NO5S, the benzene ring of the fused-ring system is twisted by 11.67 (6)° with respect to the thiazine ring. The atoms of the four-atom methyl ester group and the phenyl ring of the benzyl unit are inclined at 16.50 (7) and 44.52 (3)° with respect to the thiazine ring. An intramolecular O—H⋯O hydrogen bond gives rise to a six-membered S(6) ring motif. In the crystal, molecules are extended through a C—H⋯O interaction along the a axis. C—H⋯π interactions are also observed.
Fingerprint Verification Using the Texture of Fingerprint Image

In this paper, a fingerprint verification method is presented that improves matching accuracy by overcoming the shortcomings of previous methods due to missing some minutiae, non-linear distortions, and rotation and distortion variations. It reduces multi-spectral noise by enhancing a fingerprint image to accurately and reliably determine a reference point and then extract a 129 X 129 block, making the reference point its center. From the 4 co-occurrence matrices four statistical descriptors are computed. Experimental results show that the proposed method is more accurate than other methods the average false acceptance rate (FAR) is 0.62%, the average false rejection rate (FRR) is 0.08%, and the equal error rate (EER) is 0.35%.
Picosecond grating spectroscopy for characterizing the acoustic properties of biological material.

We present measurements of the ultrasound attenuation and sound velocity of a number of liquids, transparent biological materials (the vitreous and lens of the bovine eye), and biological fluids (whole blood) at frequencies between 925 and 1020 MHz by using a picosecond thermal grating. Sound velocity and attenuation measurements of liquids (e.g., methanol and ethanol) agree very well with those reported in the literature. The sound velocity in the biological materials studied also agrees with the reported values in the literature. In contrast, the attenuation coefficients measured for biological materials, 2000-5000 dB/cm, are much higher than would be extrapolated from published low-frequency data.
The Occurrence and Mass Distribution of Close-in Super-Earths, Neptunes, and Jupiters

Closing in on Extraterrestrial Earths With close to 500 extrasolar planets discovered to date, researchers are starting to estimate the occurrence of low-mass planets to help our understanding of how planets form and evolve. Based on observations of 166 nearby stars with the Keck Telescope, Howard et al. (p. 653) report the occurrence of short-period planets around Sun-like stars as a function of planet mass. Planet formation models predicted that planet occurrence would increase with decreasing mass, such that satellites with masses similar to that of Neptune, and less, would be more common than gas-giant planets like Jupiter. Contrary to predictions, there is no dearth of planets with masses 5 to 30 times that of Earth, implying that the models may need revision. Nevertheless, observations suggest that 23% of Sun-like stars may be orbited by a close-in, terrestrial mass planet. About one-quarter of observed Sun-like stars harbors a close-in terrestrial-mass planet. The questions of how planets form and how common Earth-like planets are can be addressed by measuring the distribution of exoplanet masses and orbital periods. We report the occurrence rate of close-in planets (with orbital periods less than 50 days), based on precise Doppler measurements of 166 Sun-like stars. We measured increasing planet occurrence with decreasing planet mass (M). Extrapolation of a power-law mass distribution fitted to our measurements, df/dlogM = 0.39 M−0.48, predicts that 23% of stars harbor a close-in Earth-mass planet (ranging from 0.5 to 2.0 Earth masses). Theoretical models of planet formation predict a deficit of planets in the domain from 5 to 30 Earth masses and with orbital periods less than 50 days. This region of parameter space is in fact well populated, implying that such models need substantial revision.
Multi-scale entanglement Renormalization Ansatz and chiral topological phases

The goal of this paper is to demonstrate a method for tensorizing neural networks based upon an efficient way of approximating scale invariant quantum states, the Multi-scale Entanglement Renormalization Ansatz (MERA). We employ MERA as a replacement for linear layers in a neural network and test this implementation on the CIFAR-10 dataset. The proposed method outperforms factorization using tensor trains, providing greater compression for the same level of accuracy and greater accuracy for the same level of compression. We demonstrate MERAlayers with 3900 times fewer parameters and a reduction in accuracy of less than 1% compared to the equivalent fully connected layers.
The Economics of Institutions, Equity, Efficiency and Effectiveness: The Case of Water Distribution in Lower Sundays River Valley, South Africa

Water supply disruptions are prevalent in various parts of South Africa. The Lower Sundays River Valley is not an exception. However, there is currently no physical shortage of water in the catchment. This study defines institutional arrangements and dynamics in the water sector in South Africa, using the Lower Sunday River Water Users Association as the case study. Key informant interviews reveal that relevant stakeholders are not adequately represented in management committees. Such institutional arrangement vacuums can lead to a failure of the water institutions in the catchment to provide water resources effectively.
NEURAL NETWORKS AS A SUPPORTING TOOL IN CREDIT GRANTING PROCEDURE

In this paper we discuss the application of artificial neural networks to the classification of the regional bank and leasing company clients. The clients of both institutions are classified taking into consideration creditworthiness, economic and financial situation of investigated firms along with decisions about allowing the credit. In the research, multilayer perceptron and radial basis function networks are used. The networks are trained applying back propagation and genetic algorithms along with Widrow – Hoff and linear vector quantization methods. The accuracy of the networks is evaluated in terms of classification errors.
Molecular dynamics simulations of ethanol binding to the transmembrane domain of the glycine receptor: Implications for the channel potentiation mechanism

The glycine receptor (GlyR) is potentiated by ethanol and other anesthetics. The potentiation mechanism at the molecular level is unknown and remains elusive, but mutagenic studies have shown that ethanol and other volatile anesthetics bind to a pocket between TM1, TM2, and TM3. The present study extends previous studies (Cheng et al., Proteins 2007;68:581–593) wherein we conducted homology modeling and molecular dynamics (MD) simulations to construct models of the homopentameric α1 subunits of the GlyR transmembrane domain in open and closed states. To understand the potentiation of GlyR by ethanol we compare the binding of ethanol molecules to the channel in these different states. We observe that ethanol stably resides inside solvent‐accessible cavities found in the open state of GlyR that are formed by I229 (of TM1) in one subunit and S267 and A288 (of TM2 and TM3, respectively) in the adjacent subunit. The volume of these putative binding pockets is state‐dependent. Selective binding to the open states of receptors has been proposed to explain the potentiating actions of this class of anesthetics. In accordance with this model, our MD simulations suggest that the potentiation of ethanol on GlyR may be effected through preferential binding of ethanol molecules to an inter‐subunit binding pocket in the open state. Proteins 2008. © 2007 Wiley‐Liss, Inc.
Company-University Collaboration Types As A Determinant For Knowledge Transfer

This paper develops a framework for a novel measurement of outcomes of diﬀerent types of company-university collaboration. We test whether the level of formalization and the type of interaction inﬂuences the outcomes, in particular knowledge transfer. We ex-tend the existing research by applying novel statistical computational methods form the ﬁeld of natural language processing to identify the knowledge transfer. We investigate how the level of formalization of collaboration aﬀects the knowledge transfer between universities and companies. Preliminary results indicate that we are able to identify additional forms of knowledge transfer and give companies insights into their potential beneﬁts from diﬀerent types of relationships. We propose a new perspective that enables companies to shape and adapt their external knowledge search as eﬀective as possible.
Ownership Structures and Stock Price Synchronicity in Brazil and Russia

ii List of Acronyms . viii List of Figures . ix List of Tables . x Author’s Declaration . xii Acknowledgements . xiii CHAPTER 1: INTRODUCTION . 1 1.1 Purpose . 1 1.2 Motivation of the Thesis . 3 1.3 Essay One: Ownership Structures and Stock Price Synchronicity in Brazil . 5 1.4 Essay Two: Ownership Structures and Stock Price Synchronicity in Russia . 8 1.5 Main Contributions of the Thesis. 9 1.6 Structure of the Thesis . 13 CHAPTER 2: CONCEPTUAL FRAMEWORK . 14 2.1 Concentrated Ownership Structures, Agency Relationships and Private Benefits of Control . 17 2.1.1 The Entrenchment Effect . 18 2.1.2 The Incentive-alignment Effect . 19 2.1.3 Entrenchment Effect under Control-Ownership Divergence . 20 2.2 Institutional-level Governance Mechanisms, Entrenchment Effects and Firms’ Information Environments . 22 2.3 Substitution Effect of Ownership Concentration for Weak Investor Protection at Higher Cash-Flow Rights. 26 2.4. Ownership Transparency and Firm’s Information Environment . 27 2.5 Overall Framework . 29 CHAPTER 3: OWNERSHIP STRUCTURES AND STOCK PRICE SYNCHRONICITY IN BRAZIL . 32 3.
Simultaneous cooling of axial vibrational modes in a linear ion trap (16 pages)

In order to use a collection of trapped ions for experiments where a well-defined preparation of vibrational states is necessary, all vibrational modes have to be cooled to ensure precise and repeatable manipulation of the ions quantum states. A method for simultaneous sideband cooling of all axial vibrational modes is proposed. By application of a magnetic field gradient the absorption spectrum of each ion is modified such that sideband resonances of different vibrational modes coincide. The ion string is then irradiated with monochromatic electromagnetic radiation, in the optical or microwave regime, for sideband excitation. This cooling scheme is investigated in detailed numerical studies. Its application for initializing ion strings for quantum information processing is extensively discussed.