Miracle-dz/UniFAR-FTUs huggingface dataset:
Optimal design of PIDA controller using harmony search algorithm for AVR power system

In this article, a new proportional, integral, derivative and acceleration (PIDA) controller is presented and designed for an automatic voltage regulator power system. The controller parameters are designed by considering as an optimization with minimization of square error using harmony search algorithm. The response of the harmony search optimized PIDA (PIDA-HSA) controller are observed and compared to the controllers in literature. The superiority is validated in terms of performance indices (ITAE, IAE and ISE).
Computer‐aided mechanogenesis of skeletal muscle organs from single cells in vitro

Complex mechanical forces generated in the growing embryo play an important role in organogenesis. Computerized mechanical application of similar forces to differentiating skeletal muscle myoblasts in vitro generate three‐dimensional artificial muscle organs. These organs contain parallel networks of long un‐branched myofibers organized into fascicle‐like structures. Tendon development is initiated and the muscles are capable of performing directed, functional work. Kinetically engineered organs provide a new method for studying the growth and development of normal and diseased tissue. —Vandenburgh, H. H. , Swasdison, S. , Karlisch, P. Computer‐aided mechanogenesis of skeletal muscle organs from single cells in vitro. FASEB J. 5: 2860‐2867; 1991.
Design of 325 MHz Single and Triple Spoke Resonators at FNAL

The proposed 8-GeV driver at FNAL is based on approximately 400 independently phased superconducting resonators. In this paper the design of 325 MHz spoke resonators, two single spoke resonators (beta = 0.21 and beta = 0.4) and a triple spoke resonator (beta = 0.62), for the high intensity neutrino source (HINS) front end is presented. We describe the optimization of the spoke resonator geometry, the goal being to minimize the EPEAK/EACC and BPEAK/EACC ratios. We report on the coupled ANSYS-MWS analysis on the resonator mechanical properties and power coupler RF design. The current status of mechanical design and slow tuning mechanism are also presented.
Audio Feedback with Reduced Self-focus as an Intervention for Social Anxiety: An Experimental Study

Abstract Background and Objectives: Socially anxious individuals tend to underestimate their performance largely due to attentional bias. Video and audio feedback (AF) with cognitive preparation (CP) have shown to improve socially anxious individuals′ evaluation of their performance in previous studies. In the present study, it was hypothesized that one of the three steps in CP, reduced self-focus (RS), is sufficient to cause an improved voice evaluation after AF. This was tested in a single-session randomized controlled experiment. Method: Forty-one socially anxious participants were asked to give a speech, then to listen to and evaluate a taped recording of their performance. Half of the sample were instructed to reduce their self-focus prior to AF, the rest received AF only. RS involved asking participants to listen to the audio recording as though they were listening to a stranger. Generalization effects were assessed by a second speech. Results: AF with RS led to more improved voice evaluations than AF-only after the first speech, and the effects remained in the evaluation of the second speech. More positive speech evaluations were associated with corresponding reductions of performance anxiety.Limitations: small sample, analogue study. Conclusion: One component of cognitive preparation—(RS)—appears to be sufficient to cause significant effects on voice evaluation in socially anxious individuals. If the results are replicated in clinical samples, AF with RS may be a promising intervention in the treatment of social anxiety.
Evaluation of the integrated cognitive model of depression and its specificity in a migrant population

This study empirically tested the specificity of the integrated cognitive model (ICM) of depression, which postulates that negative life events interact with dysfunctional attitudes to increase the frequency and severity of automatic thoughts, subsequently affecting depressive symptoms. We also examined the three competing models: the linear mediation model, the alternative etiologies model, and the symptom model. We anticipated that we might examine these models more appropriately using data from a population at an increased risk of developing depressive symptoms. As such, two‐wave panel data were obtained from a group of 107 Korean migrants who had been in Australia less than 1 year. Structural equation modeling revealed that the ICM provided an adequate and much better fit than the three competing models. The ICM was also found to support the cognitive specificity theory of depression and anxiety. These findings suggest that dysfunctional attitudes can be a common cognitive moderator of depression and anxiety, whereas automatic thoughts and anxious self‐statements can be specific cognitive mediators of anxiety and depression, respectively. Depression and Anxiety 24:112–123, 2007. © 2006 Wiley‐Liss, Inc.
MALDI-TOF MS in Prenatal Genomics

Prenatal diagnosis aims either to provide the reassurance to the couples at risk of having an affected child by timely appropriate therapy or to give the parents a chance to decide the fate of the unborn babies with health problems. Invasive prenatal diagnosis (IPD) is accurate, however, carrying a risk of miscarriage. Noninvasive prenatal diagnosis (NIPD) has been developed based on the existing of fetal genetic materials in maternal circulation; however, a minority fetal DNA in majority maternal background DNA hinders the detections of fetal traits. Different protocols and assays, such as homogenous MassEXTEND (hME), single allele base extension reaction (SABER), precise measuring copy number variation of each allele, and quantitative methylation and expression analysis using the high-throughput sensitive matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS), allow NIPD for single gene disorders, fetal blood group genotyping and fetal aneuploidies as well as the development of fetal gender-independent biomarkers in maternal circulation for management of pathological pregnancies. In this review, we summarise the use of MALDI-TOF MS in prenatal genomics.
A new tightly-regulated dual-output LLC resonant converter

A New Tightly-Regulated Dual output LLC resonant converter is proposed in this paper. The proposed converter can get tightly regulated dual-output voltages by both pulse frequency modulation (PFM) and pulse width modulation (PWM) using only one control IC compared with the conventional LLC resonant converter. Therefore, it features a simpler structure, less mass, and lower cost of production. Furthermore, since all power switches are turned on under zero-voltage switching (ZVS) condition, it has several favorable advantages such as a high-efficiency, low switching loss, improved electromagnetic interference (EMI), and reduced burden on the cooling system. This paper presents a dual-output LLC resonant converter applicable to the 40” LCD TV power supply.
Approximate K-Means + + in Sublinear Time Olivier Bachem

The quality of K-Means clustering is extremely sensitive to proper initialization. The classic remedy is to apply k-means++ to obtain an initial set of centers that is provably competitive with the optimal solution. Unfortunately, k-means++ requires k full passes over the data which limits its applicability to massive datasets. We address this problem by proposing a simple and efficient seeding algorithm for K-Means clustering. The main idea is to replace the exact D-sampling step in k-means++ with a substantially faster approximation based on Markov Chain Monte Carlo sampling. We prove that, under natural assumptions on the data, the proposed algorithm retains the full theoretical guarantees of k-means++ while its computational complexity is only sublinear in the number of data points. For such datasets, one can thus obtain a provably good clustering in sublinear time. Extensive experiments confirm that the proposed method is competitive with k-means++ on a variety of real-world, largescale datasets while offering a reduction in runtime of several orders of magnitude.
Threshold of detection of diffuse lung disease.

UNLABELLED A scintigraphic model of the lungs was used to study the threshold of detection of diffuse disease of the lungs. METHODS Randomly distributed cold lesions of 4, 8, 12 and 16 mm3 block sizes were created, occupying 0%-50% of lung tissue in steps of 1%. These were submitted for reporting to five observers each with a normal study for comparison. RESULTS No observer detected lesions of 4-mm3 block size even when up to 50% of the lung was involved. All observers detected lesions of 8-mm3 block size when a mean of 27% of lung tissue was involved with lesions. As lesion size increased to 12 and 16 mm3, observers detected lesions when a mean of 10% and 6% of lung tissue was involved, respectively. Comparison between views for each observer showed that the lateral and anterior oblique views were used more often than the anterior, posterior oblique and posterior views. CONCLUSION This model suggests that pulmonary scintigraphy has the potential to detect a diffuse disease such as emphysema at an early stage of lung involvement. In general, small anatomic lesions appear to have more profound scintigraphic consequences. However, even scintigraphic lesions of the order of size of the pulmonary acinus are easily detected.
Next-generation re-sequencing of genes involved in increased platelet reactivity in diabetic patients on acetylsalicylic acid

Abstract The objective of this study was to investigate whether rare missense genetic variants in several genes related to platelet functions and acetylsalicylic acid (ASA) response are associated with the platelet reactivity in patients with diabetes type 2 (T2D) on ASA therapy. Fifty eight exons and corresponding introns of eight selected genes, including PTGS1, PTGS2, TXBAS1, PTGIS, ADRA2A, ADRA2B, TXBA2R, and P2RY1 were re-sequenced in 230 DNA samples from T2D patients by using a pooled PCR amplification and next-generation sequencing by Illumina HiSeq2000. The observed non-synonymous variants were confirmed by individual genotyping of 384 DNA samples comprising of the individuals from the original discovery pools and additional verification cohort of 154 ASA-treated T2DM patients. The association between investigated phenotypes (ASA induced changes in platelets reactivity by PFA-100, VerifyNow and serum thromboxane B2 level [sTxB2]), and accumulation of rare missense variants (genetic burden) in investigated genes was tested using statistical collapsing tests. We identified a total of 35 exonic variants, including 3 common missense variants, 15 rare missense variants, and 17 synonymous variants in 8 investigated genes. The rare missense variants exhibited statistically significant difference in the accumulation pattern between a group of patients with increased and normal platelet reactivity based on PFA-100 assay. Our study suggests that genetic burden of the rare functional variants in eight genes may contribute to differences in the platelet reactivity measured with the PFA-100 assay in the T2DM patients treated with ASA.
Reliable information service for Internet computer conferencing

The Conferencing Information Service (CIS) described is developed to provide reliable information to users about ongoing computer conferences throughout the Internet. CIS is composed of three major components: the information daemon (ID), to store and retrieve information about the ongoing conferences in the Internet; the conference announcer (CA), to broadcast conference information to the IDs; the user interface (UI), to retrieve the current conference information from the IDs, to display the retrieved information to the user in an X-window based interface, and to allow the users to start a new conference or join a selected ongoing conference. <<ETX>>
The “Cutaneous Rabbit” Hopping out of the Body

Rapid sequential taps delivered first to one location and then to another on the skin create the somatosensory illusion that the tapping is occurring at intermediate locations between the actual stimulus sites, as if a small rabbit were hopping along the skin from the first site to the second (called the “cutaneous rabbit”). Previous behavioral studies have attributed this illusion to the early unimodal somatosensory body map. A functional magnetic resonance imaging study recently confirmed the association of the illusion with somatotopic activity in the primary somatosensory cortex. Thus, the cutaneous rabbit illusion has been confined to one's own body. In the present paper, however, we show that the cutaneous rabbit can “hop out of the body” onto an external object held by the subject. We delivered rapid sequential taps to the left and right index fingers. When the subjects held a stick such that it was laid across the tips of their index fingers and received the taps via the stick, they reported sensing the illusory taps in the space between the actual stimulus locations (i.e., along the stick). This suggests that the cutaneous rabbit effect involves not only the intrinsic somatotopic representation but also the representation of the extended body schema that results from body–object interactions.
Distance running in hot environments: a thermal challenge to the elite runner

Endurance performance is impaired in the heat, and a combination of high temperature and high humidity presents a major challenge to the elite marathon runner, who must sustain a high metabolic rate throughout the race. The optimum temperature for marathon performance is generally about 10–12 °C. The optimum temperature may be lower for faster runners than for slower runners. Sweat evaporation limits the rise in core temperature, but dehydration will impair cardiovascular function, leading to a fall in blood flow to muscle, skin and other tissues. There is growing evidence that the effects of high ambient temperature and dehydration on performance of exercise may be mediated by effects on the central nervous system. This seems to involve serotonergic and dopaminergic functions.
Hospitalist handoffs: a systematic review and task force recommendations.

BACKGROUND Handoffs are ubiquitous to Hospital Medicine and are considered a vulnerable time for patient safety. PURPOSE To develop recommendations for hospitalist handoffs during shift change and service change. DATA SOURCES PubMed (through January 2007), Agency for Healthcare Research and Quality (AHRQ) Patient Safety Network, white papers, and hand search of article bibliographies. STUDY SELECTION Controlled studies evaluating interventions to improve in-hospital handoffs (n = 10). DATA EXTRACTION Studies were abstracted for design, setting, target, outcomes (including patient-level, staff-level, or system-level outcomes), and relevance to hospitalists. DATA SYNTHESIS Although there were no studies of hospitalist handoffs, the existing literature from related disciplines and expert opinion support the use of a verbal handoff supplemented with written documentation in a structured format or technology solution. Technology solutions were associated with a reduction in preventable adverse events, improved satisfaction with handoff quality, and improved provider identification. Nursing studies demonstrate that supplementing verbal exchange with a written medium leads to improved retention of information. White papers characterized effective verbal exchange, as focusing on ill patients and actions required, with time for questions and minimal interruptions. In addition, content should be updated daily to ensure communication of the latest clinical information. Using this literature, recommendations for hospitalist handoffs are presented with corresponding levels of evidence. Recommendations were reviewed by hospitalists at the Society of Hospital Medicine (SHM) Annual Meeting and by an interdisciplinary team of expert consultants and were endorsed by the SHM governing board. CONCLUSIONS The systematic review and resulting recommendations provide hospitalists a starting point from which to improve in-hospital handoffs.
School Bullying and Suicidal Risk in Korean Middle School Students

Objective. Being a victim or a perpetrator of school bullying, the most common type of school violence, has been frequently associated with a broad spectrum of behavioral, emotional, and social problems. In a Korean middle school community sample, this study specifically investigated the prevalence of suicidal ideations and behaviors in victims, perpetrators, and victim-perpetrators of school bullying and compared them with a group of students who were in the same schools and were not involved with bullying. Methods. In a cross-sectional study, 1718 seventh- and eighth-grade students in 2 middle schools participated in the study in October 2000. Students completed demographic information, Korean Peer Nomination Inventory, and Korean Youth Self-Report. Results. Compared with the students who were not involved with school bullying, victim-perpetrators reported more suicidal/self-injurious behaviors and suicidal ideation in the previous 6 months (odds ratio [OR]: 1.9 and 1.9, respectively). In female students, all 3 school bullying groups had increased suicidal ideation for the previous 2 weeks (OR: 2.8, 2.0, and 2.8, respectively) but not in male students (OR: 0.9, 1.1, and 1.3, respectively). Conclusions. Students who were involved in school bullying, especially victim-perpetrators and female students, had significantly higher risks for suicide ideation and suicidal behavior when compared with individuals who were not involved in school bullying. In addition to attempting to decrease bullying in a community, students who are involved in school bullying should be the targets for suicide monitoring and prevention programs.
Long-acting medications for the hyperkinetic disorders

citation for published version (APA) Banaschewski, T. , Coghill, D. , Santosh, P., Zuddas, A. , Asherson, P., Buitelaar, J., Danckaerts, M. , Döpfner, M. , Faraone, S. V. , Rothenberger, A. , Sergeant, J. A. , Steinhausen, H. C. , Sonuga-Barke, E. J. S. , & Taylor, E. (2006). Long-acting medications for the hyperkinetic disorders: a systematic review and European treatment guideline. European Child and Adolescent Psychiatry, 15(8), 476-495. https://doi.org/10.1007/s00787-006-05490
An LMMSE receiver scheme for amplify-and-forward relay systems with imperfect channel state information

In realistic cases, imperfect channel state information (CSI) occur either due to an imperfect channel estimation algorithm or due to fast changing channel. In this paper, we investigate the effect of channel estimation error on the linear minimum mean square error (LMMSE) receiver in amplify-and-forward (AF) relay systems. We derive the mathematical forms of the LMMSE receiver in the presence of channel estimation error and introduce a novel receiver structure for AF relay systems, which consider the channel estimation error as a part of the total equivalent noise power on the LMMSE receiver. In order to illustrate the performance gains brought by the proposed receive scheme, received data mean square error (MSE) in the situations of channel estimation error considered and non-considered are compared. At the end of this paper, simulation results of bit error rate (BER) performance are presented to validate our theoretical analysis.
Development of risk based dynamic path finding framework using Bayesian Belief Network

Due to the rapid changes in circumstances of cooperates such as globalization, technical innovation and competition, inter-dependence among cooperates which compose supply chain has been intensified. This make cooperates be exposed to various risk and even a small uncertainty can disrupt the balance of whole supply chain. Therefore, in this paper, the framework to develop alternative execution plan to minimize the total transportation cost and expected cost from risk has been devised. In order to model the relationship between risk factors and risk propagation effect, Bayesian Belief Network (BBN) has been applied. Moreover, with the simple and fast heuristic algorithm, Dijkstra, the alternative transportation plan can be found. The result of numerical experiment shows the cost effectiveness of the proposed framework
Area-level socio-economic status and health status among adults with asthma and rhinitis

Socio-economic status (SES) may affect health status in airway disease at the individual and area level. In a cohort of adults with asthma, rhinitis or both conditions, questionnaire-derived individual-level SES and principal components analysis (PCA) of census data for area-level SES factors were used. Regression analysis was utilised to study the associations among individual- and area-level SES for the following four health status measures: severity of asthma scores and the Short Form-12 Physical Component Scale (SF-12 PCS) (n = 404); asthma-specific quality of life (QoL) scores (n = 340); and forced expiratory volume in one second (FEV1) per cent predicted (n = 218). PCA yielded a two-factor solution for area-level SES. Factor 1 (lower area-level SES) was significantly associated with poorer SF-12 PCS and worse asthma QoL. These associations remained significant after adding individual-level SES. Factor 1 was also significantly associated with severity of asthma scores, but not after addition of the individual-level SES. Factor 2 (suburban area-level SES) was associated with lower FEV1 per cent predicted in combined area-level and individual SES models. In conclusion, area-level socio-economic status is linked to some, but not all, of the studied health status measures after taking into account individual-level socio-economic status.
Organized Self-Management Support Services for Chronic Depressive Symptoms: A Randomized Controlled Trial.

OBJECTIVE This study aimed to determine whether a self-management support service was more effective than treatment as usual in reducing depressive symptoms and major depressive episodes and increasing personal recovery among individuals with chronic or recurrent depressive symptoms. METHODS The study was a randomized controlled trial of a self-management support service consisting of depression self-management training, recovery coaching, and care coordination. The 18-month intervention included regular telephone or in-person contacts with a care manager and a structured group program co-led by a professional therapist and a trained peer specialist. Intervention (N=150) and control (N=152) participants ages ≥ 18 with chronic or recurrent depressive symptoms were recruited from five clinics in Seattle, Washington. Outcome measures included the Hopkins Symptom Checklist depression scale, the Recovery Assessment Scale, the Patient-Rated Global Improvement scale, and the percentage of participants with a major depressive episode. Interviewers were masked to treatment condition. RESULTS Repeated-measures estimates of the long-term effect of the intervention versus usual care (average of the six-, 12-, and 18-month outcomes adjusted for age, gender, and site) indicated that intervention participants had less severe symptoms (p=.002) and higher recovery scores (p=.03), were less likely to be depressed (odds ratio [OR]=.52, p=.001), and were more likely to be much improved (OR=1.96, p=.001). CONCLUSIONS These findings support providing regular outreach care management and a self-care group offering a combined behavioral and recovery-oriented approach for people with chronic or recurrent depressive symptoms.