Miracle-dz/UniFAR-FTUs huggingface dataset:
Influences of experience dimensions on consumer loyalty: the case of travel agencies in East Java

In today's competitive environment in the travel industry, businesses must focus on how to create customer loyalty by adopting the overarching theory of experiential marketing. This study investigates the influence of experience dimensions (sense, feel, think, act and relate) on customer loyalty through experiential value in travel agencies in East Java. The customers who purchased travel tickets and hotel vouchers in East Java were studied for data collection. We use random probability sampling as a sample collection technique. Structural equation modelling is used to analyse the collected data. The research shows that sense, feel, think, act and relate factors have positive and significant impact on customer loyalty. This study provides policy directions to marketers who are engaged in tourism agency services and suggests that they pay attention to experience dimensions to garner customer loyalty.
Trends in cardiogenic shock: report from the SHOCK Study. The SHould we emergently revascularize Occluded Coronaries for cardiogenic shocK?

AIMS We analysed time trends in patient characteristics, management, and outcomes of cardiogenic shock complicating acute myocardial infarction in the international, prospective SHOCK Trial Registry and pre-study Registry. BACKGROUND Despite therapeutic advances in its management, the incidence and high mortality of this complication has remained unchanged for decades. However, in recent years mortality was reported to decrease in one community concomitant with increasing use of revascularization. METHODS Thirty-six centres registered 1380 patients with suspected cardiogenic shock complicating acute myocardial infarction from January 1992 to August 1997. Patient and myocardial infarction characteristics, haemodynamics, medications, procedure use, and vital status at discharge were recorded. RESULTS In all, 79% of patients had shock due to predominant pump failure (non-mechanical aetiology). The aetiology, patient profile, and clinical characteristics of cardiogenic shock did not differ over time, except for increases in the incidence of prior bypass surgery (P=0.054) and transfers to tertiary centres (P=0.008). In all, 44% underwent revascularization (n=485), with angioplasty performed more often than bypass surgery (69% vs 31%). The revascularization rate increased over time (P=0.006) with a significant decrease in the time to revascularization (P=0.033). The use of Swan-Ganz catheterization decreased over time (P=0.018), as did the mean length of hospitalization (P=0.034). Overall in-hospital mortality was high (63%) but decreased over time in all patients (P=0.004) and those with pump failure (P=0.018). Mortality was lower for patients who underwent revascularization compared to those who were not revascularized (41% vs 79%, P<0.001). CONCLUSIONS Cardiogenic shock complicating acute myocardial infarction is associated with a high mortality rate, but mortality decreased significantly from 1992 to 1997. This partly reflects the greater use of revascularization, which was associated with better outcomes. The reported international trend towards shorter admissions for myocardial infarction was also observed in this cohort.
Emotions as core building blocks of an experience

PurposeThis paper aims to stimulate the discussion in the fields of hospitality, tourism and leisure on what exactly constitutes “an experience” and how to measure it; the authors unpack the experience construct into its core constituent elements, namely, emotions.Design/methodology/approachThe paper reviews insights from psychology and cognitive neuroscience that define experiences as a fine-grained temporal succession of emotions that occur during an experiential episode. Limitations of current methods for measuring experiences are discussed, after which biometric and neuroscientific methods are reviewed that are optimally geared toward measuring emotions, as they occur during an experience with fine temporal detail.FindingsAn overview is presented of the available studies within the fields of hospitality, tourism and leisure that use these methodologies. These studies show that using these methodologies provides a fruitful methodological approach to measuring experiences in real time.Practical implicationsCompanies are constantly seeking to create memorable experiences for their customers. The proposed research methodologies allow companies to get a more fine-grained image of what impacts customers over the course of their experience and to actively integrate the use of emotions into creating experiences, as emotions are key to making them memorable.Originality/valueThe paper sketches the contours of a rapidly emerging framework that unpacks memorable experiences into their constituent element – emotions. It is proposed that this will contribute to a deeper understanding of how consumers experience offerings in the hospitality, tourism and leisure industry.
A Pilot Intervention Designed to Address Behavioral Factors That Place Overweight/Obese Young Children at Risk for Later-Life Obesity

The purpose of this pilot randomized controlled trial (RCT) was to intervene with parents of overweight/obese 4- to 8-year-old children to improve child internalizing and externalizing behaviors. Parent–child dyads (N = 60) were randomly assigned to treatment or comparison conditions. Parents attended four intervention sessions at their child’s primary health care office over 3 months. Child behaviors were assessed at 0, 3, 6, and 12 months post intervention. Parental beliefs in their skills/abilities increased in the experimental group parents, but there was no statistical difference between groups at any time. Child externalizing behaviors significantly decreased from baseline to postintervention for both groups (F = 3.26, p = .020). Post hoc model testing suggests that this change was more pronounced in the intervention group (F = 0.56, p = .692). Child somatic symptoms significantly decreased over time (F = 4.55, p = .004), and there were group differences in child depressive behaviors (F = 6.19, p = .020). These findings suggest that a parent-focused intervention program demonstrated positive preliminary effects on children’s behaviors.
Prognostic roles of absolute monocyte and absolute lymphocyte counts in patients with advanced‐stage follicular lymphoma in the rituximab era: an analysis from the FOLL05 trial of the Fondazione Italiana Linfomi

Recently, in an attempt to improve the discrimination power of the international prognostic index (IPI), patients with diffuse large B‐cell lymphoma were evaluated to determine the prognostic roles of peripheral blood absolute monocyte count (AMC) and absolute lymphocyte count (ALC). Here, we analysed data of 428 patients with follicular lymphoma (FL) enrolled in a prospective, randomized trial (FOLL05 study) conducted by Fondazione Italiana Linfomi, to assess the impact of AMC and ALC on progression‐free survival (PFS). All patients had been treated with one of three treatment combinations: (i) rituximab (R) plus cyclophosphamide, vincristine and prednisone; (ii) R plus cyclophosphamide, doxorubicin, vincristine and prednisone or (iii) R plus mitoxantrone and fludarabine. We showed that only AMC was a powerful predictor of PFS, and possibly overall survival, in patients with FL treated with combination chemotherapy regimens that contained R. The AMC can be used alone as a novel, simple factor that can predict survival outcome in patients with FL, independent of the immunochemotherapy regimen. It may therefore be widely used by clinicians, due to its simplicity and broad applicability. Additionally, it can be combined with other factors that determine the IPI or FLIPI, to increase the discriminating ability of these indices.
Improved automated optic cup segmentation based on detection of blood vessel bends in retinal fundus images

Glaucoma is a leading cause of permanent blindness. Retinal imaging is useful for early detection of glaucoma. In order to evaluate the presence of glaucoma, ophthalmologists may determine the cup and disc areas and diagnose glaucoma using a vertical optic cup-to-disc (C/D) ratio and a rim-to-disc (R/D) ratio. Previously we proposed a method to determine cup edge by analyzing a vertical profile of pixel values, but this method provided a cup edge smaller than that of an ophthalmologist. This paper describes an improved method using the locations of the blood vessel bends. The blood vessels were detected by a concentration feature determined from the density gradient. The blood vessel bends were detected by tracking the blood vessels from the disc edge to the primary cup edge, which was determined by our previous method. Lastly, the vertical C/D ratio and the R/D ratio were calculated. Using forty-four images, including 32 glaucoma images, the AUCs of both the vertical C/D ratio and R/D ratio by this proposed method were 0.966 and 0.936, respectively.
Consumer spending on spectator sports, physical activity, and gambling: evidence from Canada

The question of the extent of complementarity between sports betting and spending on spectator sports viewing is addressed in this chapter using Canadian household spending data. They find that spending on betting and spending on spectator sports are indeed complementary. Intriguingly, they also find that betting and spending on sports participation are substitutes. This suggests that further deregulation of sports gambling in Canada could well lead to less physical activity and more sedentary life styles for Canadians.
Grey Relational Analysis of Economic Policy Uncertainty in Selected European Union Countries

To estimate the mutual effect of economic policy among European countries, the correlation among economic policy uncertainty (EPU)indices of eight countries in European Union (EU) from March 2003 to January 2017 is studied by using grey relational analysis (GRA). The result shows that under the framework of European economic integration, grey relational degree of EPU of European countries are all above 0.8, which reflects a strong economic policy co-movement of EU countries. The EPU indices of the UK and France with large economic mass are hardly influenced by other countries, which indicate that the economic policy influences of the two countries are larger than those of other countries. Additionally, due to the influence of exiting from the EU, the UK exhibits the lowest and dramatically fluctuating economic policy correlation with the other countries in recent years.
Gait Characteristics Over the Course of a Race in Recreational Marathon Competitors

We analyzed gait and function of the supporting limb in participants of a marathon race at three stages: prerace, midrace (18 km), and near the end of the race (36 km). We confirmed that the most successful runners were able to maintain running speed for the duration of the race with little change in speed or gait. Speed slowed progressively during the race for those with slower race times, but stride frequency–stride length relationships remained normal for the speed they ran. These findings differ from most lab-based studies of fatigue, in which runners are forced to match a constant preset treadmill speed. Small changes in maximum ground force were seen in both slow- and fast-running participants as race end approached.
Mental health in Lithuania

Lithuania is a country with an approximate area of 65 000 km2. Its population is 3.422 million, and the gender ratio (expressed as men per 100 women) is 87. The proportion of the population under the age of 15 years is 18%, and the proportion above the age of 60 years is 20%. The literacy rate is 99.6% for both men and women. The country is in the higher middle-income group (by World Bank 2004 criteria).
Evaluation of a multidisciplinary rehabilitation program with emphasis on musculoskeletal disorders: a 5-year follow-up.

OBJECTIVE The aim of this study was to perform a 5-year follow-up of a 7-week multidisciplinary rehabilitation program focusing on pain, physical disability, anxiety and depression as well as stress and sick leave and to compare the results from the baseline, a 2-year follow-up and this 5-year follow-up. PARTICIPANTS Out of 60 participants of the original rehabilitation program 54 were followed-up after 5 years. METHODS The rehabilitation program was individually adapted and consisted of physical activity in several forms as well as theoretical and practical education. At baseline (start of study) and 2 and 5 years after completion of the rehabilitation program all participants were evaluated in terms of sick leave, pain rating (Visual Analogue Scale), the Disability Rating Index, Hospital Anxiety and Depression Scale, and Stress Test. RESULTS Between the start of the program and the 5-year follow-up pain rating (P< 0.017) and the rate of full-time sick leave (P< 0.0005) decreased. Physical disability, anxiety, depression and stress were maintained from the 2-year follow-up until the 5-year follow-up. CONCLUSIONS The rehabilitation program seemed to have had an effect on the participant's ability to manage with symptoms long after the end of the rehabilitation program. Most participants had returned to work, and reported less pain. The improvements made in physical disability and mental health prior to the 2-year follow-up were maintained at the 5-year follow-up occasion.
Cross‐country Evidence of the Relationship Between Resilience and the Subjective Perception of Well‐being and Social Inclusion: Evidence from the Regions of Matam (Senegal) and the Triangle of Hope (Mauritania)

Resilience, commonly perceived as an unobservable household characteristic, has been defined differently according to each measurement approach utilized. This paper contributes to the literature, both conceptually, by reviewing the link between resilience, subjective well‐being and social inclusion; and analytically, by providing statistical evidence of whether subjective measures of well‐being are associated with higher household resilience. The paper shows that those who perceive themselves and their community to be involved in the decision‐making process related to policies and service provision are associated with greater resilience capacity. The empirical evidence is based on two household surveys in Senegal and Mauritania. Copyright © 2017 John Wiley & Sons, Ltd.
Dual energy CT material decomposition from inconsistent rays (MDIR)

In dual energy CT (DECT) the object is scanned with two different detected spectra in order to provide material-selective or energy-selective images of the object. Thereby, generally a higher order correction of beam hardening artifacts than it can be applied to usual single energy scans is possible. All known methods to do that need to combine the sinograms in rawdata space before image reconstruction. Therefore, a precondition of those methods is that geometrically identical rays are measured for each sinogram (consistent rays). However, most CT scanners actually acquire inconsistent rays in the sense that geometrically different rays are measured for each spectrum. Then the possibility of higher order beam hardening corrections remains unused and the resulting dual energy specific images show significantly reduced quality. We propose an iterative algorithm for material decomposition from inconsistent rays (MDIR) that allows even in the case of inconsistent rays to reconstruct material-selective or energy-selective images that are almost free of beam hardening artifacts. The algorithm is assessed using simulated data without noise (to enhance the visibility of beam hardening artifacts) and a micro CT scan of a mouse. The simulation studies find that the method is able to completely remove beam hardening caused image quality degradation after few (two to four) iterations. For the mouse scan an improvement in image quality can be noticed. In any case MDIR succeeds in reducing image artifacts that origin from beam hardening considerably while the image noise remains constant.
Bayesian point process modeling to quantify excess risk in spatial epidemiology: an analysis of stillbirths with a maternal contextual effect

Motivated by the paucity of high quality stillbirth surveillance data and the spatial analyses of such data, the current research sets out to quantitatively describe the pattern of stillbirth events that may lead to mechanistic hypotheses. We broaden the appeal of Bayesian Poisson point process modeling to quantify excess risk while considering a form of a log Gaussian Cox process. To evaluate the integral term in the likelihood function, the realized point pattern can be augmented with design points and a simple numerical quadrature scheme can be pursued; however, because in many epidemiologic settings the complete realized point pattern is observed, it is effectively impossible to measure spatially referenced covariates at these design points. We consider a practical geostatistical strategy to interpolate spatially referenced covariate values to the design points. We also study the utility of parameterizing the intensity function to include a maternal contextual effect to account for variation due to multiple stillbirth events experienced by the same mother in independent pregnancies. Simulation studies suggest that the proposed geostatistical strategy approximates the integral reasonably well and that there is a variance-bias trade-off associated with the use of a maternal contextual effect. The methodology is applied to the spatial distribution of stillbirth events in Iowa during the years 2005 through 2011 obtained using an active, statewide public health surveillance approach. Several localized areas of excess risk were identified and mapped based on model components that captured the nuanced and salient features of the data. A conditional formulation of the point process model is then considered, which has two main advantages: the ability to easily incorporate covariate information attached to both stillbirth and live birth, as well as obviate the need to estimate the background intensity. We assess the utility of the conditional approach in the presence of unobserved heterogeneity, compare the integrated nested Laplace algorithm with Markov chain Monte Carlo sampling for Bayesian estimation, and extend the conditional formulation to adequately capture spatio-temporal effects. The motivating study comes from v the Iowa Registry for Congenital and Inherited Disorders who has a committed interest in the surveillance and epidemiology of stillbirth in Iowa and whether the occurrence might be geographically linked.
Extracellular matrix from human umbilical cord-derived mesenchymal stem cells as a scaffold for peripheral nerve regeneration

The extracellular matrix, which includes collagens, laminin, or fibronectin, plays an important role in peripheral nerve regeneration. Recently, a Schwann cell-derived extracellular matrix with classical biomaterial was used to mimic the neural niche. However, extensive clinical use of Schwann cells remains limited because of the limited origin, loss of an autologous nerve, and extended in vitro culture times. In the present study, human umbilical cord-derived mesenchymal stem cells (hUCMSCs), which are easily accessible and more proliferative than Schwann cells, were used to prepare an extracellular matrix. We identified the morphology and function of hUCMSCs and investigated their effect on peripheral nerve regeneration. Compared with a non-coated dish tissue culture, the hUCMSC-derived extracellular matrix enhanced Schwann cell proliferation, upregulated gene and protein expression levels of brain-derived neurotrophic factor, glial cell-derived neurotrophic factor, and vascular endothelial growth factor in Schwann cells, and enhanced neurite outgrowth from dorsal root ganglion neurons. These findings suggest that the hUCMSC-derived extracellular matrix promotes peripheral nerve repair and can be used as a basis for the rational design of engineered neural niches.
Atomic resolution structures of oxidized [4Fe-4S] ferredoxin from Bacillus thermoproteolyticus in two crystal forms: systematic distortion of [4Fe-4S] cluster in the protein.

Diffraction data of two crystal forms (forms I and II) of [4Fe-4S] ferredoxin from Bacillus thermoproteolyticus have been collected to 0.92 A and 1.00 A resolutions, respectively, at 100 K using synchrotron radiation. Anisotropic temperature factors were introduced for all non-hydrogen atoms in the refinement with SHELX-97, in which stereochemical restraints were applied to the protein chain but not to the [4Fe-4S] cluster. The final crystallographic R-factors are 9.8 % for 7.0-0.92 A resolution data of the form I and 11.2 % for the 13.3-1.0 A resolution data of the form II. Many hydrogen atoms as well as multiple conformations for several side-chains have been identified. The present refinement has revised the conformations of several peptide bonds and side-chains assigned previously at 2.3 A resolution; the largest correction was that the main-chain of Pro1 and the side-chain of Lys2 were changed by rotating the C(alpha)-C bond of Lys2. Although the overall structures in the two crystal forms are very similar, conformational differences are observed in the two residues at the middle (Glu29 and Asp30) and the C-terminal residues, which have large temperature factors. The [4Fe-4S] cluster is a distorted cube with non-planar rhombic faces. Slight but significant compression of the four Fe-S bonds along one direction is observed in both crystal forms, and results in the D(2d) symmetry of the cluster. The compressed direction of the cluster relative to the protein is conserved in the two crystal forms and consistent with that in one of the clusters in Clostridium acidurici ferredoxin.
Sequential chemoradiotherapy with gemcitabine and cisplatin for locoregionally advanced nasopharyngeal carcinoma

We investigated a new chemoradiotherapy (CRT) regimen for locoregionally advanced nasopharyngeal carcinoma (NPC). A total of 240 patients were randomly assigned to three different CRT regimens: sequential CRT [1 cycle chemotherapy + Phase I radiotherapy (RT) + 1 cycle chemotherapy + Phase II RT + 2 cycles chemotherapy] with a cisplatin–gemcitabine (GC) regimen (800 mg/m2 gemcitabine on Days 1 and 8 and 20 mg/m2 cisplatin on Days 1–5, every 4 weeks) (sGC‐RT); sequential chemoradiotherapy with a cisplatin–fluorouracil (PF) regimen (20 mg/m2 DDP and 500 mg/m2 5‐FU on Days 1–5, every 4 weeks) (sPF‐RT) and cisplatin‐based concurrent chemoradiotherapy plus adjuvant PF chemotherapy (Con‐RT + PF). The complete response rate was higher in the sGC + RT group than in the other two groups (98.75% vs. 92.50%, p < 0.01). The 3‐year overall survival (OS), disease‐free survival (DFS) and distant metastasis‐free survival (DMFS) rates in the sGC‐RT group were significantly higher than those observed in the Con‐RT group (OS, 95.0% vs. 76.3%, p < 0.001; DFS, 89.9% vs. 67.5%, p < 0.001; DMFS, 92.5% vs. 76.0%, p = 0.004) and in the sPF + RT group (OS, 95.0% vs. 73.6%, p < 0.001; DFS, 89.9% vs. 63.3%, p < 0.001; DMFS, 92.5% vs. 74.7%, p = 0.002). There were no significant differences in 3‐year OS, DFS and MFS rates between the Con‐RT and the sPF‐RT groups. The GC‐RT group experienced more hematologic toxicity, constipation and rash; however, there were no differences in late RT toxicity between the groups. These results demonstrate that a sGC‐RT regimen is effective and well tolerated in patients with locoregionally advanced NPC.