Miracle-dz/UniFAR-FTUs huggingface dataset:
Expression of a Micro-protein*

The smallest known open reading frame encodes the ribosomal protein L41, which in yeast is composed of only 24 amino acids, 17 of which are arginine or lysine. Because of the unique problems that might attend the translation of such a short open reading frame, we have investigated the properties and the translation of the mRNAs encoding L41. In Saccharomyces cerevisiaeL41 is encoded by two linked genes, RPL41A andRPL41B. These genes give rise to mRNAs that have short 5′ leaders of 18 and 22 nucleotides and rather long 3′ leaders of 203 and 210 nucleotides not including their poly(A) tails. The mRNAs are translated exclusively on monosomes, suggesting that ribosomes do not remain attached to the mRNA after termination of translation. Calculations based on the abundance of ribosomes and of L41 mRNA indicate that the entire translation event, from initiation through termination, must occur in ∼2 s. Termination of translation after only 25 codons does not subject the mRNAs encoding L41 to nonsense-mediated decay. Surprisingly, despite the L41 ribosomal protein being conserved from the archaea through the mammalia, S. cerevisiae can grow relatively normally after deletion of bothRPL41A and RPL41B.
The Role of Mothers' and Fathers' Parental Control and Coparenting in Toddlers' Compliance

Research Findings: This study examined the unique and relative contributions of mothers' and fathers' parental control and coparenting to toddlers' committed compliance with parents in both dyadic parent–child and triadic family play contexts. Sixty-eight mostly middle-class, 2-parent families with toddlers (16–37 months) were observed in a university laboratory setting. There were positive associations among mothers' gentle guidance, balanced coparental engagement, and child committed compliance with mothers. However, there was no association between any parental control or coparenting variable and child compliance with fathers. Unique contributions of fathers' control and coparenting, beyond mothers' parenting, were found for children's compliance with mothers but not with fathers. Practice or Policy: The findings highlight the importance of taking the family relationship context into account when assessing parenting behaviors and toddlers'compliance.
Further Clarification Regarding Validity and Education

opportunity to present our ideas on validity, a topic that we consider to be of utmost importance ("A Suggested Change in Terminology and Emphasis Regarding Validity and Education," this issue, pp. 437-448). We would also like to thank the distinguished discussants-Susan E. Embretson, Joanna S. Gorin, Robert J. Mislevy, Pamela A. Moss, and Stephen G. Sireci-for their thoughtful and challenging comments (also in this issue of the journal) regarding our article. We wish we had more time and space to respond to all of the interesting remarks and excellent suggestions for improvement in our understanding of validity. Because the editors have restricted us to 2,500 words, our response will be limited to a brief summarization of our position emphasizing three elements that some of the discussants interpreted somewhat differently from our intention or about which we have a truly different opinion. Those elements are (a) the unitary theory, (b) validity terminology, and (c) the construct-versus-content debate. We will spend little time addressing specific points raised by the discussants, although the temptation is great.
Memory Bandwidth Management for Efficient Performance Isolation in Multi-Core Platforms

Memory bandwidth in modern multi-core platforms is highly variable for many reasons and it is a big challenge in designing real-time systems as applications are increasingly becoming more memory intensive. In this work, we proposed, designed, and implemented an efficient memory bandwidth reservation system, that we call MemGuard. MemGuard separates memory bandwidth in two parts: guaranteed and best effort. It provides bandwidth reservation for the guaranteed bandwidth for temporal isolation, with efficient reclaiming to maximally utilize the reserved bandwidth. It further improves performance by exploiting the best effort bandwidth after satisfying each core's reserved bandwidth. MemGuard is evaluated with SPEC2006 benchmarks on a real hardware platform, and the results demonstrate that it is able to provide memory performance isolation with minimal impact on overall throughput.
Ray-tracing Procedural Displacement Shaders

Displacement maps and procedural displacement shaders are a widely used approach of specifying geometric detail and increasing the visual complexity of a scene. While it is relatively straightforward to handle displacement shaders in pipeline based rendering systems such as the Reyes-architecture, it is much harder to efficiently integrate displacement-mapped surfaces in ray-tracers. Many commercial ray-tracers tessellate the surface into a multitude of small triangles. This introduces a series of problems such as excessive memory consumption and possibly undetected surface detail. In this paper we describe a novel way of ray-tracing procedural displacement shaders directly, that is, without introducing intermediate geometry. Affine arithmetic is used to compute bounding boxes for the shader over any range in the parameter domain. The method is comparable to the direct ray-tracing of Bézier surfaces and implicit surfaces using Bézier clipping and interval methods, respectively.
Personality and implicit social cognition research: past, present and future

The commentary to this special issue discusses how current research on implicit and automatic processes in personality is related to previous attempts to conceptualise and measure automatic or implicit aspects of personality that are difficult to assess using standard self‐report measures. The six original contributions of this issue are discussed in the light of earlier works and with respect to interesting research questions emerging from them. We point to a range of new implicit measures of personality, discuss current trends in implicit personality research and conclude with suggestions how future research could use implicit personality measures to improve our understanding of self‐regulatory and problem behaviour. Copyright © 2007 John Wiley & Sons, Ltd.
A Sketch-based Approach for Multimedia Retrieval

A hand-drawn sketch is a convenient way to search for an image or a video from a database where examples are unavailable or textual queries are too difficult to articulate. In this thesis, we have tried to propose solutions for some problems in sketch-based multimedia retrieval. In case of image search, the queries could be approximate binary outlines of the actual objects. In case of videos, we consider the case where the user can specify the motion trajectory using a sketch, which is provided as a query. However there are multiple problems associated with this paradigm. Firstly, different users sketch the same query differently according to their own perception of reality. Secondly, sketches are sparse and abstract representations of images and the two modalities can not be compared directly. Thirdly, compared to images, datasets of sketches are rare. It is very difficult, if not impossible to train a system with sketches of every possible category. The features should be robust enough to retrieve classes that were not a part of training. In this thesis, the work can be broadly divided into three parts. First, we develop a motion-trajectory based video retrieval strategy and propose a representation for sketches that aims to reduce the perceptual variability among different users. We also propose a novel retrieval strategy, which combines multiple feature representations for a final result using a cumulative scoring mechanism. In order to tackle the problem of multiple modalities, we propose a sketch-based image retrieval strategy by mapping the two modalities into a lower dimensional sub-space where they are maximally correlated. We use Cluster Canonical Correlation Analysis (c-CCA), a modified version of standard CCA, for the mapping. Finally, we investigate the use of semantic features derived from a Convolutional Neural Network, and extend the idea of sketch-based image retrieval to the task of zero-shot learning or unknown class retrieval. We define an objective function for the network such that, while training, a close miss is penalized less than a distant miss. Our training encodes semantic similarity among the different classes. We perform experiments to evaluate our algorithms on well known datasets and our results show that our features perform reasonably well in challenging scenarios.
Ridge preservation with acellular dermal matrix and anorganic bone matrix cell-binding peptide P-15 after tooth extraction in humans.

BACKGROUND Preventing ridge collapse with the extraction of maxillary anterior teeth is vital to an esthetic restorative result. Several regenerative techniques are available and are used for socket preservation. The aim of this study is to analyze by clinical parameters the use of acellular dermal matrix (ADM) and anorganic bovine bone matrix (ABM) with synthetic cell-binding peptide P-15 to preserve alveolar bone after tooth extraction. METHODS Eighteen patients in need of extraction of maxillary anterior teeth were selected and randomly assigned to the test group (ADM plus ABM/P-15) or the control group (ADM only). Clinical measurements were recorded initially and at 6 months after ridge-preservation procedures. RESULTS In the clinical measurements (external vertical palatal measurement [EVPM], external vertical buccal measurement [EVBM], and alveolar horizontal measurement [AHM]) the statistical analysis showed no difference between test and control groups initially and at 6 months. The intragroup analysis, after 6 months, showed a statistically significant reduction in the measurements for both groups. In the comparison between the two groups, the differences in the test group were as follows: EVPM = 0.83 ± 1.53 mm; EVBM = 1.20 ± 2.02 mm; and AHM = 2.53 ± 1.81 mm. The differences in the control group were as follows: EVPM = 0.87 ± 1.13 mm; EVBM = 1.50 ± 1.15 mm; and AHM = 3.40 ± 1.39 mm. The differences in EVPM and EVBM were not statistically significant; however, in horizontal measurement (AHM), there was a statistically significant difference (P<0.05). CONCLUSION The results of this study show that ADM used as membrane associated with ABM/P-15 can be used to reduce buccal-palatal dimensions compared to ADM alone for preservation of the alveolar ridge after extraction of anterior maxillary teeth.
Efficient Strategy to Identify Gene-Gene Interactions and Its Application to Type 2 Diabetes

Over the past decade, the detection of gene-gene interactions has become more and more popular in the field of genome-wide association studies (GWASs). The goal of the GWAS is to identify genetic susceptibility to complex diseases by assaying and analyzing hundreds of thousands of single-nucleotide polymorphisms. However, such tests are computationally demanding and methodologically challenging. Recently, a simple but powerful method, named “BOolean Operation-based Screening and Testing” (BOOST), was proposed for genome-wide gene-gene interaction analyses. BOOST was designed with a Boolean representation of genotype data and is approximately equivalent to the log-linear model. It is extremely fast, and genome-wide gene-gene interaction analyses can be completed within a few hours. However, BOOST can not adjust for covariate effects, and its type-1 error control is not correct. Thus, we considered two-step approaches for gene-gene interaction analyses. First, we selected gene-gene interactions with BOOST and applied logistic regression with covariate adjustments to select gene-gene interactions. We applied the two-step approach to type 2 diabetes (T2D) in the Korea Association Resource (KARE) cohort and identified some promising pairs of single-nucleotide polymorphisms associated with T2D.
Tradeoffs in Networked Feedback Systems: From Information-Theoretic Measures to Bode-Type Integrals

This paper investigates performance limitation issues of multivariable networked feedback systems with multiport communication channels. We develop a general information-theoretic paradigm for analyzing the limitations and tradeoffs imposed by communication channels, which is enabled by the development of new information measures and Bode-type integral inequalities. The integral inequalities quantify the tradeoffs in disturbance attenuation for broad classes of systems consisting of linear time-invariant plants and causal, possibly nonlinear, time-varying stabilizing controllers communicating over general noisy channels with causal encoders and decoders. The channel blurredness, a newly developed information measure for the quality of multiport communication channels, is used to characterize the effect of communication channel constraints on the integrals and henceforth the tradeoff in disturbance attenuation. For several canonical channels with power constraints, such as additive white Gaussian noise channels, additive colored Gaussian noise channels, and fading channels, we derive explicit forms for the channel blurredness, which, together with the Bode-type integral inequalities, show that to mitigate the noise effect on performance tradeoff, the power of the communication channels must be distributed in ways fundamentally different from the Shannon’s classical “water-filling” power allocation policy.
Accurate statistical spoken language understanding from limited development resources

Robust spoken language understanding (SLU) is a key component of spoken dialogue systems. Recent statistical approaches to this problem require additional resources (e.g. gazetteers, grammars, syntactic treebanks) which are expensive and time-consuming to produce and maintain. However, simple datasets annotated only with slot-values are commonly used in dialogue systems development, and are easy to collect, automatically annotate, and update. We show that it is possible to reach state-of-the-art performance using minimal additional resources, by using Markov logic networks (MLNs). We also show that performance can be further improved by exploiting long distance dependencies between slot-values. For example, by representing such features in MLNs, but without using a gazetteer, we outperform the hidden vector state (HVS) model of He and Young 2006 (1.26% improvement, a 13% error reduction).
Hypercollecting semantics and its application to static analysis of information flow

We show how static analysis for secure information flow can be expressed and proved correct entirely within the framework of abstract interpretation. The key idea is to define a Galois connection that directly approximates the hyperproperty of interest. To enable use of such Galois connections, we introduce a fixpoint characterisation of hypercollecting semantics, i.e. a "set of sets" transformer. This makes it possible to systematically derive static analyses for hyperproperties entirely within the calculational framework of abstract interpretation. We evaluate this technique by deriving example static analyses. For qualitative information flow, we derive a dependence analysis similar to the logic of Amtoft and Banerjee (SAS '04) and the type system of Hunt and Sands (POPL '06). For quantitative information flow, we derive a novel cardinality analysis that bounds the leakage conveyed by a program instead of simply deciding whether it exists. This encompasses problems that are hypersafety but not k-safety. We put the framework to use and introduce variations that achieve precision rivalling the most recent and precise static analyses for information flow.
Satisfaction of Users of the Family Health Strategy in a Capital City of Northeast Brazil

Objective: To analyze the satisfaction of users of the Family Health Strategy in relation to the Reliability and Safety aspects. Method: This is a quantitative research carried out with 353 participants enrolled in an Integrated Health Center of the eastern region of a capital in the Northeast Brazil, through the SERVQUAL instrument. The data collection took place from January to May 2015, the research was approved by the Ethics and Research Committee of the UNINOVAFAPI University Center. Results: The results indicated that in the Reliability dimension, participants agreed that the healthcare professionals record the attendance, perform on the promised date and have an interest in solving the problems. In the Security dimension, the majority of the participants were indifferent as to the behavior of the professionals generating confidence. They demonstrated security in requesting the services because they were politely attended by the professionals. Moreover, in the two dimensions analyzed, it was noticed that there is a tendency to increase satisfaction as the participants' income decreases with significant statistical relations, with satisfaction on Reliability and Security inversely proportional to income. Conclusion: It is considered that users of the Family Health Strategy have demonstrated satisfaction with the services received, however, there is a need for more studies with different methodological approaches to better elucidate the intersubjective issues that shape the process of interaction between users, healthcare professionals and services. Keywords: Family health; patient satisfaction; security.
Image Quality Estimation Using Integral Indicator

Automatic image quality estimation allows to compare the results received with the help of different processing algorithms based on a big sample of original frames as well as to estimate the effect of their application in different shooting scenes. The work describes automatic generation of normalized integral estimation of image visual quality. Its relevance for single frames and for series of video frames is experimentally confirmed.
Leptospira Species in Floodwater during the 2011 Floods in the Bangkok Metropolitan Region, Thailand

Floodwater samples (N = 110) collected during the 2011 Bangkok floods were tested for Leptospira using culture and polymerase chain reaction (PCR); 65 samples were PCR-positive for putatively non-pathogenic Leptospira species, 1 sample contained a putatively pathogenic Leptospira, and 6 samples contained Leptospira clustering phylogenetically with the intermediate group. The low prevalence of pathogenic and intermediate Leptospira in floodwater was consistent with the low number of human leptospirosis cases reported to the Bureau of Epidemiology in Thailand. This study provides baseline information on environmental Leptospira in Bangkok together with a set of laboratory tests that could be readily deployed in the event of future flooding.
Identification and Control of Discrete-Time Nonlinear Systems Using Affine Support Vector Machines

Support vector machine (SVM) is a universal learning method. In this paper, an affine support vector machine (ASVM) for regression is presented for identification and control of input-affine nonlinear models. ASVM is a variant of SVM and so inherits its merits. The solution to ASVM is cast into a convex quadratic programming (QP). Hence ASVM has a unique global solution. In addition, the curse of dimensionality is avoided because ASVM is insensitive to the dimensionality of data. A commonly used model for a nonlinear system is a nonlinear autoregressive exogenous (NARX) model. ASVM could get good performance in both identification and control if a NARX model can be well represented by an input-affine nonlinear model. The experimental results validate the efficiency of ASVM in identification and control of discrete-time nonlinear systems.
Ocular surface and salivary gland involvement in patients with autoimmune thyroid disease

Purpose: Many reports have indicated an association between thyroid dieases and primary Sjogren’s syndrome (pSS). The aim of our study was to evaluate the outcomes of the tests used for dry eye diagnosis and salivary gland involvement in patients with autoimmune thyroiditis. Methods: Forty-two patients (group 1) with autoimmune thyroid disease and 30 controls (group 2) were selected. Tear film break up time, Schirmer I test, Schirmer II test, ocular staining with 1% rose Bengal and salivary gland cintilography were performed in both groups. Results: Regarding the ocular surface damage observed by Rose Bengal test there was no difference between groups (p=0.77). For tear film break up time the groups did not differ statistically (p=0.46). There was no statistical difference between groups 1 and control in scintigraphy of the salivary gland (p=0.99). A statistical difference between the patients with thyroid disease and the control group was seem only in the Schirmer II test (p=0.0009). Conclusions: No patients fulfilled all criteria for Sjogren’s syndrome. It is possible that it could be underestimated.
Tacit knowledge in professional firms: the teachings of firms in very puzzling situations

Professional firms (i.e. consulting, lawyers, etc.) accumulate and apply knowledge that they build collaboratively with their clients, partners and other knowledge intensive firms. Tacit knowledge, i.e. knowledge that can be acted, but cannot be expressed, circulates back‐and‐forth from clients to consultants. This paper explores patterns of capitalization of tacit knowledge in professional firms.
Randomized controlled trial of transdiagnostic group treatments for primary care patients with common mental disorders

Background. The purpose was to test the effectiveness of two transdiagnostic group interventions compared to care as usual (CAU) for patients with anxiety, depressive or stress-related disorders within a primary health care context. Objectives. To compare the effects of cognitive-based-behavioural therapy (CBT) and multimodal intervention (MMI) on the quality of life and relief of psychological symptoms of patients with common mental disorders or problems attending primary health care centre. Methods. Patients (n = 278), aged 18–65 years, were referred to the study by the GPs and 245 were randomized to CAU or one of two group interventions in addition to CAU: (i) group CBT administered by psychologists and (ii) group MMI administered by assistant nurses. The primary outcome measure was the Mental Component Summary score of short form 36. Secondary outcome measures were Perceived Stress Scale and Self-Rating Scale for Affective Syndromes. The data were analysed using intention-to-treat with a linear mixed model. Results. On the primary outcome measure, the mean improvement based on mixed model analyses across post- and follow-up assessment was significantly larger for the MMI group than for the CBT (4.0; P = 0.020) and CAU (7.5; P = .001) groups. Participants receiving CBT were significantly more improved than those in the CAU group. On four of the secondary outcome measures, the MMI group was significantly more improved than the CBT and CAU groups. The course of improvement did not differ between the CBT group and the CAU group on these measures. Conclusions. Transdiagnostic group treatment can be effective for patients with common mental disorders when delivered in a primary care setting. The group format and transdiagnostic approach fit well with the requirements of primary care.