Miracle-dz/UniFAR-FTUs huggingface dataset:
RDF Resource Search and Exploration with LinkZoo

The Linked Data paradigm is the most common practice for publishing, sharing and managing information in the Data Web. Linkzoo is an IT infrastructure for collaborative publishing, annotating and sharing of Data Web resources, and their publication as Linked Data. In this paper, we overview LinkZoo and its main components, and we focus on the search facilities provided to retrieve and explore RDF resources. Two search services are presented: (1) an interactive, two-step keyword search service, where live natural language query suggestions are given to the user based on the input keywords and the resource types they match within LinkZoo, and (2) a keyword search service for exploring remote SPARQL endpoints that automatically generates a set of candidate SPARQL queries, i.e., SPARQL queries that try to capture userâ? s information needs as expressed by the keywords used. Finally, we demonstrate the search functionalities through a use case drawn from the life sciences domain.
Performance evaluation of HD camcorders: measuring texture distortions using Gabor filters and spatio-velocity CSF

This paper presents a new method of measuring physical texture distortions (PhTD) to evaluate the performance of high de_nition (HD) camcorders w.r. t. motion and lossy compression. It is extended to measure perceptual texture distortions (PeTD) by taking into account the spatio-velocity contrast sensitivity function of the human visual system. The PhTD gives an objective (physical) distortion of texture structures, while the PeTD measures the perceptual distortion of textures. The dead leaves chart, invariant to scaling, translation, rotation, and contrast, was selected as a target texture. The PhTD/PeTD metrics of the target distorted by camcorders were measured based on a bank of Gabor _lters with eight orientations and three scales. Experimental results for six HD camcorders from three vendors showed: 1) the PhTD value increases monotonically w.r. t. the motion speed, and decreases monotonically w.r. t. the lossy compression bitrate; 2) the PeTD value decreases monotonically w.r. t. the motion speed, but stays almost constant w.r. t. the lossy compression bitrate. The experiment gives a reasonable result even if the distortions are not radially symmetric. However, some subjective tests should be done in future work to validate the performance of the perceptual texture distortion metric.
[A neuropsychological and functional brain imaging study of visuo-imitative apraxia].

We describe the case of a 58-years-old right-handed women suffering from an occipital-parietal lesion. The administration of a cognitively based assessment tool for limb praxis (Batterie d'Evaluation des Praxies, B.E.P., Peigneux and Van der Linden, 1998) demonstrated bilateral visuo-imitative apraxia. Gesture production was mainly characterised by spatial, errors, and imitation of meaningful gestures was worse than their pantomime on verbal command. Moreover, the imitation of meaningless gestures and their reproduction on a manikin were worse than imitation of their matched meaningful gestures. In a cognitive perspective, adapted from the Rothi et al. (1997) and Goldenberg (1995) contributions to our understanding of limb praxis, this configuration of performance suggests deficits occurring at multiple levels. On one hand, it suggests either access difficulties or alteration of the output praxicon, i.e., the lexicon for visuo-kinesthetic engrams of meaningful gestures. On the other hand, the simultaneous deficit for meaningless gesture reproduction on the subject's own body and on a manikin favors an alteration of the structural descriptions of the human body (i.e., human body knowledge), underlying the mental transposition processes occurring between the visual analysis of a meaningless gestural configuration and its effective reproduction on oneself or on a manikin, thus contradicting the classic view of a direct pathway linking visual analysis and motor planning in meaningless gesture imitation. Finally, due to the output praxicon deficit, imitation of meaningful gestures is partly processed in the same way as meaningless gestures (also impaired in this case), leading to an interference effect between both degraded memory-based and visually-transposed traces, which account for imitation of meaningful gestures being worse than their pantomime on verbal command. We also assess regional cerebral metabolism using positron emission tomography (PET). Comparison with 41 healthy subjects (SPM96) demonstrated a statistically significant hypometabolism in the left intraparietal sulcus and superior parietal lobule, and in the right dorsal prestriate cortex. These results, together with a review of the other studies of visuo-imitative apraxia, suggest that the left intraparietal sulcus may be associated with access or integration of information from the output praxicon. The left superior parietal and the right dorsal prestriate deficits functionally impaired a bilateral dorsal network implied in the mental transformations of the body, thus suggesting that these mental transformations are underlined by knowledge of the human body, which may subsequently explain the deficit for the reproduction of meaningless and meaningful configurations.
Insulin resistance in severe acne vulgaris

Introduction Acne vulgaris is a pilosebaceous gland disease that usually affects people from puberty to young adulthood. It is seen especially on the face, neck, trunk and arms. Its severity differs from patient to patient and its pathogenesis is multifactorial. The main pathogenic factors of acne are high sebaceous gland secretion, follicular hyperproliferation, high androgen effects, propionibacterium acnes colonization and inflammation. Diet is always thought a probable reason for acne and many studies are done about acne and diet. Aim To determine the effect of insulin resistance in severe acne vulgaris. Material and methods Two hundred and forty-three acne vulgaris patients and 156 healthy controls were enrolled into the study. The blood levels of insulin and glucose were measured. Homeostasis Model Assessment (HOMA) Index was calculated. The values were compared with the control group. Results All of the patients were in the severe acne group according to their scores on the global acne scoring scale. While fasting blood glucose levels were not different between the groups (p > 0.05, 82.91 ±9.76 vs. 80.26 ±8.33), the fasting insulin levels were significantly higher in the patient group than in the control group (p < 0.001, 14.01 ±11.94 vs. 9.12 ±3.53). Additionally, there was a highly significant difference between the patient and control groups in terms of HOMA values (p < 0.001, 2.87 ±2.56 vs. 1.63 ±0.65). Conclusions These results suggest that insulin resistance may have a role in the pathogenesis of acne.
The synthesis of cyclic combinational circuits

Digital circuits are called combinational if they are memoryless: they have outputs that depend only on the current values of the inputs. Combinational circuits are generally thought of as acyclic (i.e., feed-forward) structures. And yet, cyclic circuits can be combinational. Cycles sometimes occur in design synthesized from high-level descriptions. Feedback in such cases is carefully contrived, typically occurring when functional units are connected in a cyclic topology. Although the premise of cycles in combinational circuits has been accepted, and analysis techniques have been proposed, no one has attempted the synthesis of circuits with feedback at the logic level. We propose a general methodology for the synthesis of multilevel combinational circuits with cyclic topologies. Our approach is to introduce feedback in the substitution/minimization phase, optimizing a multilevel network description for area. In trials with benchmark circuits, many were optimized significantly, with improvements of up to 30% in the area. We argue the case for radically rethinking the concept of "combinational" in circuit design: we should no longer think of combinational logic as acyclic in theory or in practice, since nearly all combinational circuits are best designed with cycles.
Novel Visual Representations for Software Metrics Using 3D and Animation

The visualization of software metrics is an important step towards a better understanding of the software product to be developed. Software metrics are quanti- tative measurements of a piece of software, e.g., a class, a package, or a component. A good understanding of software metrics supports the identification of possible prob- lems in the development process and helps to improve the software quality. In this paper, we present two possibilities how novel visual representations can support the user to discover interesting properties within the metric data set. The first one uses a new interactive 3D metaphor to overcome known problems in the visualization of the evolution of software metrics. Then, we focus on the usage of 2D animation to repre- sent metric values. Both approaches were implemented and address different aspects in human-centered visualization, i.e., the design of visual metaphors that are intuitive from the user perspective in the first case as well as the support of patterns in motion to facilitate the visual perception of metric outliers in the second case.
Repetitive Behavior and Restricted Interests in Young Children with Autism: Comparisons with Controls and Stability Over 2 Years

Restricted, repetitive and stereotyped patterns of behavior, interests and activities [RRBs] are among the core symptoms of autism spectrum disorders (ASD). Previous studies have indicated that RRBs differentiate ASD from other developmental disorders and from typical development. This study examined the presentation of RRBs as reported on the Repetitive Behavior Scale‐Revised, a caregiver report, in children with ASD [separated into autism and Pervasive Developmental Disorder‐Not Otherwise Specified groups] compared with children with nonspectrum developmental delays or typical development. We examined the role of age, cognitive functioning, sex and social communication impairment as they relate to RRBs. The stability of RRBs in children with autism was also examined over the course of 2 years. Results of the study confirmed that the amount and type of RRBs differs by diagnosis. Age, cognitive functioning, sex and social‐communication impairment were not significant correlates. Among children with autism, RRBs remained stable over time. Autism Res 2013, 6: 584–595. © 2013 International Society for Autism Research, Wiley Periodicals, Inc.
Survival, disease manifestations, and early predictors of disease progression among children with perinatal human immunodeficiency virus infection in Thailand.

OBJECTIVE To describe survival and signs of human immunodeficiency virus (HIV) infection in perinatally infected children in Thailand. METHODS At 2 large Bangkok hospitals, 295 infants born to HIV-infected mothers were enrolled at birth from November 1992 through September 1994 and followed up with clinical and laboratory evaluations every 1 to 3 months for 18 months. Infected children remained in follow-up thereafter. For the infected children, we used data collected through October 2000 to estimate survival times and compare characteristics among those whose disease progressed at rapid (died within 1 year), intermediate (died at 1-5 years), and slow (survived at least 5 years) rates. RESULTS None of the 213 uninfected children died during the follow-up period. Of the 68 infected children, 31 (46%) died; median survival was 60 months (95% confidence interval: 31-89 months). The most common cause of death was pneumonia (52% of deaths). Thirty-two children (47%) started antiretroviral therapy. Six children died in their first year before developing specific signs of HIV infection; all others developed signs of HIV infection between 1 and 42 months old (median: 4 months). Severe clinical (Centers for Disease Control and Prevention Class C) conditions were diagnosed in 23 children at a median age of 12 months, 15 (65%) of whom died a median of 3 months later. Compared with children whose disease progressed slowly, those whose disease progressed rapidly gained less weight by 4 months old (median 1.7 vs 2.6 kg), and their mothers had higher viral loads (median 5.1 vs 4.5 log(10) copies/mL) and lower CD4(+) counts (median 350 vs 470 cells/ micro L) at delivery. CONCLUSIONS Among HIV-infected Thai children, survival times are longer than among children in many African countries, but shorter than among children in the United States and Europe. Signs of HIV develop early in most children. Growth failure and advanced maternal disease can predict rapid HIV disease progression and may be useful markers for treatment decisions.
Exploiting Locality in Searching the Web

Published experiments on spidering the Web suggest that, given training data in the form of a (relatively small) subgraph of the Web containing a subset of a selected class of target pages, it is possible to conduct a directed search and find additional target pages significantly faster (with fewer page retrievals) than by performing a blind or uninformed random or systematic search, e.g., breadthfirst search. If true, this claim motivates a number of practical applications. Unfortunately, these experiments were carried out in specialized domains or under conditions that are difficult to replicate. We present and apply an experimental framework designed to reexamine and resolve the basic claims of the earlier work, so that the supporting experiments can be replicated and built upon. We provide high-performance tools for building experimental spiders, make use of the ground truth and static nature of the WT10g TREC Web corpus, and rely on simple well understand machine learning techniques to conduct our experiments. In this paper, we describe the basic framework, motivate the experimental design, and report on our findings supporting and qualifying the conclusions of the earlier research.
Admission Lipoprotein-Associated Phospholipase A2 Activity Is Not Associated with Long-Term Clinical Outcomes after ST-Segment Elevation Myocardial Infarction

Background Lipoprotein-associated phospholipase A2 (Lp-PLA2) activity is a biomarker predicting cardiovascular diseases in a real-world. However, the prognostic value in patients undergoing primary percutaneous coronary intervention (pPCI) for ST-segment elevation myocardial infarction (STEMI) on long-term clinical outcomes is unknown. Methods Lp-PLA2 activity was measured in samples obtained prior to pPCI from consecutive STEMI patients in a high-volume intervention center from 2005 until 2007. Five years all-cause mortality was estimated with the Kaplan-Meier method and compared among tertiles of Lp-PLA2 activity during complete follow-up and with a landmark at 30 days. In a subpopulation clinical endpoints were assessed at three years. The prognostic value of Lp-PLA2, in addition to the Thrombolysis In Myocardial Infarction or multimarker risk score, was assessed in multivariable Cox regression. Results The cohort (n = 987) was divided into tertiles (low <144, intermediate 144–179, and high >179 nmol/min/mL). Among the tertiles differences in baseline characteristics associated with long-term mortality were observed. However, no significant differences in five years mortality in association with Lp-PLA2 activity levels were found; intermediate versus low Lp-PLA2 (HR 0.97; CI 95% 0.68–1.40; p = 0.88) or high versus low Lp-PLA2 (HR 0.75; CI 95% 0.51–1.11; p = 0.15). Both in a landmark analysis and after adjustments for the established risk scores and selection of cases with biomarkers obtained, non-significant differences among the tertiles were observed. In the subpopulation no significant differences in clinical endpoints were observed among the tertiles. Conclusion Lp-PLA2 activity levels at admission prior to pPCI in STEMI patients are not associated with the incidence of short and/or long-term clinical endpoints. Lp-PLA2 as an independent and clinically useful biomarker in the risk stratification of STEMI patients still remains to be proven.
Educational Leadership: Ambiguity, Professionals and Managerialism

PART ONE: THE NATURE OF IRONY Introducing the Ironic Perspective Endemic Ambiguities The Preconditions Of Irony The Ambiguities of Policy Implementation PART TWO: IRONY AND MANAGERIALISM From Management to Managerialism A Solution in Search of a Problem PART THREE: THE RHETORIC OF MANAGERIALISM AND LEADERSHIP The Myth of Transformation Transmissional Leadership for Political Transformation PART FOUR: THE IRONIC RESPONSE AND THE FUTURE OF MANAGERIALISM Patterns of Ironic Response The Ironic Orientation and Professional Practice Temperate Leadership and Management Living With Irony
Audio Information for Hyperlinking of TV Content

In this paper, we explore the use of audio information in the retrieval of multimedia content. Specifically, we focus on linking similar segments in a collection consisting of 4,000 hours of BBC TV programmes. We provide a description of our system submitted to the Hyperlinking Sub-task of the Search and Hyperlinking Task in the MediaEval 2014 Benchmark, in which it scored best. We explore three automatic transcripts and compare them to available subtitles. We confirm the relationship between retrieval performance and transcript quality. The performance of the retrieval is further improved by extending transcripts by metadata and context, by combining different transcripts, using the highest confident words of the transcripts, and by utilizing acoustic similarity.
Consumer acceptance of ingenic foods

Recent advances in plant molecular biology offer a means of reaping the benefits of biotechnology, while potentially assuaging consumer concerns by re‐inserting native DNA back into plants. Results are presented from nationwide surveys in the U.S. and France, indicating that more consumers would accept ingenic plants than transgenic plants, with twice as many U.S. than French consumers considering food produced through biotechnology eatable.
Discovering Hypernymy Relations using Text Layout

Hypernymy relation acquisition has been widely investigated, especially because taxonomies, which often constitute the backbone structure of semantic resources are structured using this type of relations. Although lots of approaches have been dedicated to this task, most of them analyze only the written text. However relations between not necessarily contiguous textual units can be expressed, thanks to typographical or dispositional markers. Such relations, which are out of reach of standard NLP tools, have been investigated in well specified layout contexts. Our aim is to improve the relation extraction task considering both the plain text and the layout. We are proposing here a method which combines layout, discourse and terminological analyses, and performs a structured prediction. We focused on textual structures which correspond to a well defined discourse structure and which often bear hypernymy relations. This type of structure encompasses titles and sub-titles, or enumerative structures. The results achieve a precision of about 60%.
Proximity of Two Oppositely Oriented Reentrant Loops in the Glutamate Transporter GLT-1 Identified by Paired Cysteine Mutagenesis*

Sodium- and potassium-coupled transporters clear the excitatory neurotransmitter glutamate from the synaptic cleft. Their function is essential for effective glutamatergic neurotransmission. Glutamate transporters have an unusual topology, containing eight membrane-spanning domains and two reentrant loops of opposite orientation. We have introduced pairwise cysteine substitutions in several structural elements of the GLT-1 transporter. A complete inhibition of transport by Cu(II)(1,10-phenanthroline)3 is observed in the double mutants A412C/V427C and A364C/S440C, but not in the corresponding single mutants. No inhibition is observed in more then 20 other double cysteine mutants. The Cu(II)(1,10-phenanthroline)3 inhibition can be partly prevented by the nontransportable glutamate analogue dihydrokainate. Treatment with dithiothreitol restores much of the transport activity. Moreover, micromolar concentrations of cadmium ions reversibly inhibit transport catalyzed by A412C/V427C and A364C/S440C double mutants, but not by the corresponding single mutants. Inhibition by Cu(II)(1,10-phenanthroline)3 and by cadmium is only observed when the cysteine pairs are introduced in the same polypeptide. Therefore, in both cases the proximity appears to be intra- rather than intermolecular. Positions 364 and 440 are located on reentrant loop I and II, respectively. Our results suggest that these two loops, previously shown to be essential for glutamate transport, come in close proximity.
Fault Injection using Crowbars on Embedded Systems

Causing a device to incorrectly execute an instruction or store faulty data is well-known strategy for attacking cryptographic implementations on embedded systems. One technique to generate such faults is to manipulate the supply voltage of the device. This paper introduces a novel technique to introduce those supply voltage manipulations onto existing digital systems, requiring minimal modifications to the device being attacked. This uses a crowbar to short the power supply for controlled periods of time. High-accuracy faults are demonstrated on the 8-bit AVR microcontroller, which can generate both single and multi-bit faults with high repeatability. Additionally this technique is demonstrated on a FPGA where it is capable of generating faults in both internal registers and the configuration fabric.
The Eighth and Ninth Transmembrane Domains in Organic Anion Transporting Polypeptide 1B1 Affect the Transport Kinetics of Estrone-3-Sulfate and Estradiol-17β-D-glucuronide

Organic anion transporting polypeptide (OATP) 1B1 and OATP1B3 are responsible for the hepatic uptake of organic anions. They share similar sequences and structures with 12 putative transmembrane domains (TMs). Their substrate specificities are very broad and overlap each other, whereas each transporter specifically recognizes certain substrates. Because the homology of the amino acid sequence in the latter part of OATP1B1 and OATP1B3 is relatively low, to determine which TMs in the latter part of OATP1B1 are important for its substrate recognition, we constructed several cell lines expressing chimeric transporters in which some TMs of OATP1B1 were substituted with those of OATP1B3, and we investigated the transport kinetics of estrone-3-sulfate (E-sul; a substrate preferentially accepted by OATP1B1) and estradiol-17β-d-glucuronide (EG; a substrate accepted by both transporters). As the number of substituted TMs at the N terminus with those of OATP1B3 increased, the Km value of E-sul greatly increased and its uptake clearance decreased. The substitution of TM7 or TM9 of OATP1B1 with that of OATP1B3 (named 1B1-TM7 or 1B1-TM9) did not change the transport kinetics of EG, whereas the Km value of E-sul in 1B1-TM9 increased 7.4-fold. Conversely, the substitution of TM8 resulted in an 18-fold increase in the Km value of E-sul and abolished the transporter-mediated uptake of EG. These results suggest that TM8 in OATP1B1 is critical for the substrate recognition of both E-sul and EG and that TM9 is important for the recognition of E-sul, whereas it is interchangeable with that of OATP1B3 for EG transport.