Miracle-dz/UniFAR-FTUs huggingface dataset:
Modelling the association between weight status and social deprivation in English school children: Can physical activity and fitness affect the relationship?

Abstract Background: The association between being overweight/obese and deprivation is a serious concern in English schoolchildren. Aim: To model this association incorporating known confounders and to discover whether physical fitness and physical activity may reduce or eliminate this association. Subjects and methods: Cross-sectional data were collected between 2007–2009, from 8053 10–16 year old children from the East-of-England Healthy Heart Study. Weight status was assessed using waist circumference (cm) and body mass (kg). Deprivation was measured using the Index of Multiple Deprivation (IMD). Confounding variables used in the proportional, allometric models were hip circumference, stature, age and sex. Children’s fitness levels were assessed using predicted VO2 max (20-metre shuttle-run test) and physical activity was estimated using the Physical Activity Questionnaire for Adolescents or Children. Results: A strong association was found between both waist circumference and body mass and the IMD. These associations persisted after controlling for all confounding variables. When the children’s physical activity and fitness levels were added to the models, the association was either greatly reduced or, in the case of body mass, absent. Conclusions: To reduce deprivation inequalities in children’s weight-status, health practitioners should focus on increasing physical fitness via physical activity in areas of greater deprivation.
A Code in the Nose

The mammalian nose is arguably the best chemical detector on the planet, capable of detecting and discriminating among many thousands of compounds. This ability is mediated at the earliest steps by a large family of G protein (heterotrimeric guanine nucleotide-binding protein)–coupled receptors (GPCRs). The capacity to detect and discriminate odors depends on a combinatorial code, in which any given receptor recognizes many odors and any given odor compound might serve as a ligand at multiple receptors. Recent research adds a layer of complexity to the interpretation of this olfactory code, suggesting that the overall effect of a mixture of odorants is not simply equal to the sum of its parts. Rather, individual odorants can act as antagonists at the level of individual GPCRs, thereby suppressing some of the signaling pathways activated by structurally related compounds. Thus, the odor code not only is a function of the pattern of activated receptors, but also may be further sharpened by the action of antagonism. It seems that odor coding is now a division of pharmacology.
Efficient Java exception handling in just‐in‐time compilation

Java uses exceptions to provide elegant error handling capabilities during program execution. However, the presence of exception handlers complicates the job of the just‐in‐time (JIT) compiler, while exceptions are rarely used in most programs. This paper describes two techniques for reducing such complications. First, we delay the translation of an exception handler until the exception really occurs. This on‐demand translation of exception handlers allows more optimizations when translating the main flow, without being hindered by constraints caused by the exception flows. Secondly, for those exceptions that are actually thrown during program execution we insert exception‐type check code and a direct branch to the translated exception handlers. This exception handler prediction is motivated by an observation that frequently thrown exceptions are likely to be handled by the same exception handlers, so this will eliminate the exception processing overhead of the Java virtual machine. Our experiments indicate that the code quality of the main flow is no longer affected by the presence of exception handlers. Also, frequently thrown exceptions can be efficiently handled by the exception handler prediction. Copyright © 2004 John Wiley & Sons, Ltd.
Emergent Endovascular Recanalization for Cervical Internal Carotid Artery Occlusion in Patients Presenting With Acute Stroke

BACKGROUND:Acute proximal (cervical) internal carotid artery (ICA) occlusion may cause ischemia of an entire hemisphere or no ischemia at all, depending on the presence of intracranial collaterals. OBJECTIVE:To retrospectively analyze the clinical results for emergent endovascular carotid recanalization in patients with acute proximal (cervical) ICA occlusion and to assess predictors of recanalization and clinical, neurological, and functional outcome. METHODS:Emergent endovascular revascularization was attempted in 22 patients presenting with acute stroke secondary to complete cervical ICA occlusion. Patients with pseudo-occlusion were excluded. Recanalization was assessed with the Thrombolysis in Myocardial Ischemia (TIMI) system: grade 0 (no flow) to grade 3 (normal flow). RESULTS:The median age of the patients was 65 years; mean admission National Institutes of Health Stroke Scale (NIHSS) score was 14. Recanalization (TIMI grade 2/3) occurred in 17 patients (77.3%). Ten patients (45.5%) demonstrated significant clinical improvement during hospitalization (NIHSS improved ≥4 points). Fifty percent of patients had good outcomes (modified Rankin Scale ≤2) after a median follow-up of 3 months. Patient age <70 years and successful recanalization (TIMI grade 2/3) predicted a good outcome (P ≤ .01). Presence of atrial fibrillation, admission NIHSS score ≥20, and complete ICA occlusion at all levels (cervical, petrocavernous, and intracranial) were associated with poor outcomes (P ≤ .05). Patients with complete cervical ICA occlusion but partial distal preservation of the vessel were most likely to benefit from the intervention (recanalization in 88.2%; good outcome in 64.7%). CONCLUSION:Attempts at emergent endovascular carotid recanalization for acute stroke are encouraged, particularly in younger patients with partial distal preservation of the ICA.
Expression of a 31‐kDa lactoside‐binding lectin in normal human gastric Mucosa and in primary and metastatic gastric carcinomas

The expression of lactoside‐binding lectin L‐31 was analyzed in normal mucosa and in primary and metastatic gastric carcinomas. Immunoblotting revealed L‐31 lectin in extracts of normal and malignant gastric tissues from 26 patients. The L‐31 level was higher in tumor than in normal tissue in 9/26 cases, similar in 14/26 cases, and lower in 3/26 cases. Anti‐L‐31 monoclonal antibodies (MAbs) were used in immunohistochemical analyses to compare lectin expression in specimens of primary gastric carcinomas and adjacent normal mucosa from 39 patients and in specimens of metastases and the corresponding primary gastric carcinomas from 74 patients. The lectin was detected in normal gastric epithelial cells and in all gastric carcinoma specimens, albeit in varying amounts. The L‐31 level was significantly higher in the primary tumor than in adjacent normal tissue in 55% of the well‐differentiated tubular carcinoma cases and in 50% of stage‐III and ‐IV tumors. L‐31 expression in liver metastases from well‐differentiated tubular primary gastric carcinomas was higher in 31% of the cases relative to the corresponding primary cancers. Likewise, L‐31 expression in metastases from poorly differentiated gastric carcinomas in lymph nodes was higher in 38% of the cases compared to the primary cancers. The higher expression of L‐31 in primary cancers and metastases of certain types implicates this lectin in the metastatic phenotype, but the presence of L‐31 in a primary cancer is not sufficient to allow the metastatic propensity of the tumor to be predicted.
Aménagements des activités des formés au sein d'un dispositif hybride de formation et retombées sur leur activité professionnelle : une étude de cas dans le cadre de la formation de tuteurs de terrain de professeurs stagiaires

Encore majoritaires, les modeles de formation professionnelle menes en presentiel sont de plus en plus « bouscules » par d’autres modeles exploitant des outils d’enseignement en ligne (Karsenti, Garry & Benziane, 2012). L’association de ces modeles a permis l’emergence de dispositifs dits « hybrides » de formation (DHF) fondes sur l’alternance entre des activites de formation menees soit en presentiel, soit en autonomie a distance sur une plateforme concue a cet effet (Jezegou, 2014). L’etude de la litterature du domaine laisse toutefois apparaitre que peu de travaux interrogent la nature de la conception des DHF et des retombees sur l’activite des formes et des formateurs y etant impliques.Cette these s’inscrit dans un programme de recherche mene en anthropologie culturaliste dont l’objet central est l’etude de la construction du sujet professionnel en formation (Chalies & Bertone, 2017). La recherche a visee transformative dont elle rend compte, explore les effets de la scenarisation d’un DHF, concue a partir de postulats empruntes a une theorie de la formation d’adultes (Bertone & Chalies, 2015), sur l’activite conjointe de tuteurs de stage novices ayant la responsabilite d’enseignants stagiaires et de celle d’un formateur universitaire.Les resultats de l’etude montrent que la structuration des activites singulieres de formation deployees au sein du DHF a permis aux tuteurs novices de progressivement engager des capacites de signification, d’analyse et de realisation simulee de l’activite de conseil pedagogique. Alors meme que c’etait la le fondement de l’hypothese de recherche, les resultats soulignent toutefois qu’il n’a pas ete possible de constater d’apprentissage effectif en fin de formation. Cette these ouvre neanmoins de nouvelles perspectives technologiques en termes de conception de dispositifs hybrides de formation professionnelle.
On the Need for an Integrated Large-Scale Methodology of Coastal Management: A Methodological Proposal

Sustainable management of coastal areas involves dealing with problems such as coastal erosion, rapid growth in the rate of urbanization, tourism, environmental degradation associated with industrial and urban activities. Besides consideration is provided for the effects of climate change, whose scenarios also have significant consequences on coastal systems that are already extremely vulnerable and prone to many human pressures. Over the years, several international and national studies have been conducted to deepen the coastal processes. To date—despite considerable efforts—there are still problems. Two relevant priorities emerge: managing coastal risks and ensuring sustainable coastal management. In response to the above-mentioned challenges, it is worthwhile to elaborate an integrated methodology that, basing on the collection, analysis and evaluation of data, may provide an effective guideline for the successful implementation of each action, while providing timely and targeted information for the adoption of governance strategies concerning the prevention and management of marine-coastal risks. In the present study, considering what emerged in the major research projects on the coastal field during the last decades, a methodological proposal is outlined to pursue the principles of the integrated coastal zona management (ICZM) and join the managing coastal risks with sustainable uses focusing on the implementation scale.
Intertextuality as Power: Rosa Mayreder's Response to Goethe's Faust and the Cult of Male Genius

Abstract:This article positions Rosa Mayreder's Faustian tale Anda Renata, ein Mysterium in zwei Teilen und zwölf Bildern within a canon of female Faust narratives and explores what it means for a nineteenth- century female writer to "write back" to one of Germany's most revered and widely read authors, Johann Wolfgang von Goethe. I argue that Mayreder employs intertextuality as a strategic tool of resistance while writing and operating within a male- dominated literary landscape that relegates women's writings to the periphery. Using Stephanie Hilger and Audre Lorde to frame my theoretical arguments, I explore how Mayreder "writes back" to the male- dominated canon and how her work fits into feminist narratives from the early nineteenThcentury through today.
Long Term Solar Radiation Forecast Using Computational Intelligence Methods

The point prediction quality is closely related to the model that explains the dynamic of the observed process. Sometimes the model can be obtained by simple algebraic equations but, in the majority of the physical systems, the relevant reality is too hard to model with simple ordinary differential or difference equations. This is the case of systems with nonlinear or nonstationary behaviour which require more complex models. The discrete time-series problem, obtained by sampling the solar radiation, can be framed in this type of situation. By observing the collected data it is possible to distinguish multiple regimes. Additionally, due to atmospheric disturbances such as clouds, the temporal structure between samples is complex and is best described by nonlinear models. This paper reports the solar radiation prediction by using hybrid model that combines support vector regression paradigm and Markov chains. The hybrid model performance is compared with the one obtained by using other methods like autoregressive (AR) filters, Markov AR models, and artificial neural networks. The results obtained suggests an increasing prediction performance of the hybrid model regarding both the prediction error and dynamic behaviour.
High intestinal lactase concentration in adult Pakistanis.

Probably this patient's abdominal pain was related to his hyperlipidaemia, though its nature remains obscure. When given a high-fat intake he developed severe pain associated with gross chylomicronaemia; treatment directed at lowering his serum triglyceride rendered him symptom free. This patient is of interest because, atypically, his serum triglyceride concentration was raised only modestly, except during the attack apparently provoked by a high-fat intake. He was classified as having type IV hyperlipoproteinaemia, though he had intermittent fasting chylomicronaemia. Dietary restriction of fat did not prevent his attacks of pain, but carbohydrate restriction did, presumably by reducing his endogenous triglyceride production. The distinction between types IV and V hyperlipoproteinaemia may well not be absolute, chylomicronaemia in the latter sometimes reflecting the degree of hypertriglyceridaemia rather than a different metabolic fault.5 Indeed, possibly the quantity of triglyceride to be transported may partly determine the size and nature of the transporting particles.5 This case re-emphasises the need to determine the serum lipid concentration in patients with obscure abdominal pain.
Development of Mental Health Indicators in Korea

Objective Promoting mental health and preventing mental health problems are important tasks for international organizations and nations. Such goals entail the establishment of active information networks and effective systems and indicators to assess the mental health of populations. This being said, there is a need in Korea develop ways to measure the state of mental health in Korea. Methods This paper reviews the mental health indicator development policies and practices of seven organizations, countries, and regions: WHO, OECD, EU, United States, Australia, UK, and Scotland. Using Delphi method, we conducted two surveys of mental health indicators for experts in the field of mental health. The survey questionnaire included 5 domains: mental health status, mental health factor, mental health system, mental health service, and quality of mental health services. We considered 124 potential mental health indicators out of more than 600 from indicators of international organizations and foreign countries. Results We obtained the top 30 mental health indicators from the surveys. Among them, 10 indicators belong to the mental health system. The most important five mental health indicators are suicide rate, rate of increase in mental disorder treatment, burden caused by mental disorders, adequacy of identifying problems of mental health projects and deriving solutions, and annual prevalence of mental disorders. Conclusion Our study provides information about the process for indicator development and the use of survey results to measure the mental health status of the Korean population. The aim of mental health indicator development is to improve the mental health system by better grasping the current situation. We suggest these mental health indicators can monitor progress in efforts to implement reform policies, provide community services, and involve users, families and other stakeholders in mental health promotion, prevention, care and rehabilitation.
Binding of complement regulators to invasive nontypeable Haemophilus 3 influenzae is not increased compared to nasopharyngeal isolates , but serum 4 resistance is linked to disease severity 5 6 7

26 27 The aim of the present study was to analyse the importance for non-typeable Haemophilus 28 influenzae (NTHi) isolated from patients with sepsis (invasive isolates) compared to 29 nasopharyngeal isolates from patients with upper respiratory tract infection to resist the 30 complement-mediated attack in human serum and to correlate this to disease severity. We in 31 detail studied and characterized cases of invasive NTHi disease. All patients with invasive 32 NTHi isolates were adults and 35 % had a clinical presentation of severe sepsis according to 33 the ACCP/SCCM classification of sepsis grading. Moreover, 41 % of the cases had evidence 34 of immune deficiency. The different isolates were analyzed for survival in human serum, for 35 binding of [I]-labeled purified human complement inhibitors C4b-binding protein (C4BP), 36 Factor H and vitronectin in addition to binding of regulators directly from serum. No 37 significant differences were found when blood and nasopharyngeal isolates were compared, 38 suggesting that interactions with the complement system are equally important for NTHi 39 strains irrespectively of isolation site. Interestingly, a correlation between serum resistance 40 and invasive disease severity was found. The ability to resist the attack of the complement 41 system seems to be important for NTHi strains infecting the respiratory tract as well as the 42 blood stream. 43 44 45 46
RELEASE FLUX UNDERLYING CA 2 + TRANSIENTS AND CA 2 + SPARKS IN SKELETAL MUSCLE

1. Abstract 2. Introduction 3. From global Ca signal to Ca 2+ release flux 4. Ca 2+ sparks 4.1. Morphology of sparks 4.1. 1. Amplitude 4.1. 2. Spatial Width 4.1. 3. Rise Time 4.1. 4. Signal Mass 5. Approaches to release flux 5.1. Simulations 5.2. Calculations of release flux 5.2. 1. The Removal Terms 5.2. 2. Graphic Example 5.2. 3. A Lower Bound 5.3. Other estimates of release current 5.4. Artificially induced events 5.5. Non-events 6. Consequences and Conclusions 6.1. Single channels and sparks 6.2. Single channels and global release flux 7. Acknowledgements 8. References
Diazepam and Desmethyldiazepam Plasma Concentrations in Chronic Anxious Outpatients

Within the framework of a large-scale clinical study on the effect of diazepam in chronic anxiety, diazepam (D) and desmethyldiazepam (DD) plasma concentrations were determined frequently. Significant relationships were found between the clinical effect and the plasma concentrations of D and DD, respectively; a curvilinear relationship resulted if the dosage was disregarded, but within the individual dosage groups the relationship was found to be linear. For these computations, the daily diazepam dose was treated as a covariable in a factorial analysis of variance approach. It was found, in addition, that the daily diazepam dose was one of the most significant predictors of the plasma concentration of D or DD, respectively. The steady state plasma concentrations were highest in patients experiencing an exacerbation of their conditions of anxiety if they were returned to placebo after 14 to 22 weeks of diazepam medication. The lowest steady state concentrations were found with those patients who showed withdrawal symptoms under these conditions.
Design frequency reconfigurable microstrip patch antenna for S-band applications

This paper presents a technique of frequency reconfigurable microstrip patch antenna for S-band applications. The proposed antenna is using the DGS technique which uses three PIN diodes with three rectangular slots. These slot are cut in the ground to produces eight reconfigurable different frequency bands. The proposed antenna designed on FR-4 substrate with dielectric constant 4.1 and thickness 1.5mm. The simulation of the proposed work is conducted with CST. In the proposed design, radiation pattern and directivity at different frequencies are obtained. The simulated return loss is greater than 10 dB for all the bands at different frequencies.
Quantitative analysis of substance P‐immunoreactive boutons on physiologically characterized dorsal horn neurons in the cat lumbar spinal cord

A quantitative analysis of substance P (SP)‐immunoreactive (IR) terminals contacting physiologically characterized dorsal horn neurons was performed. Three types of neuron were studied: nociceptive specific (NS) from lamina I (n = 3), wide dynamic range (WDR) from laminae II‐IV (n = 3), and nonnociceptive (NN) from lamina IV (n = 3). The nociceptive response of focus was a slow, prolonged depolarization to noxious stimuli, because this response was previously shown to be blocked by selective neurokinin‐1 (NK‐1) receptor antagonists.
A Review of Recognition Techniques in ALPR Systems

‘Automatic License Plate Recognition (ALPR)’ is the process of locating & extracting plate information from images or videos. The extracted information is essential for several everyday applications, ranging from automated payment services (parking, toll roads payment collection, etc.) to more critical applications, like border security and traffic surveillance. The format of license plate varies from region to region, so the ALPR systems also tend to be region-specific. The paper presents a state-of-the-art review of earlier work done in this field of technology, especially, the recognition technique.
Optimal Pixel-to-Shift Standard Deviation Ratio for Training 2-Layer Perceptron on Shifted 60 × 80 Images with Pixel Distortion in Classifying Shifting-Distorted Objects

Abstract An optimization problem of classifying shifting-distorted objects is studied. The classifier is 2-layer perceptron, and the object model is monochrome 60 × 80 image. Based on the fact that previously the perceptron has successfully been attempted to classify shifted objects with a pixel-to-shift standard deviation ratio for training, the ratio is optimized. The optimization criterion is minimization of classification error percentage. A classifier trained under the found optimal ratio is optimized additionally. Then it effectively classifies shifting-distorted images, erring only in one case from eight takings at the maximal shift distortion. On average, classification error percentage appears less than 2.5 %. Thus, the optimized 2-layer perceptron outruns much slower neocognitron. And the found optimal ratio shall be nearly the same for other object classification problems, when the number of object features varies about 4800, and the number of classes is between two and three tens.
A Comparison of Student Learning Outcomes in Traditional and Online Personal Finance Courses

Numerous studies have compared student outcomes in online classes and traditional classes, but with mixed results. This paper adds to the existing body of evidence through an examination of students in Personal Finance courses. Primary results indicate that the delivery method made little difference in student performance. Secondary results identify pre-course GPAs, and to a lesser extent ACT scores, as predictors of student success in Personal Finance.