Miracle-dz/UniFAR-FTUs huggingface dataset:
A functional near-infrared spectroscopy based lie detector

Deception involves complex neural processes and correlates in the brain. Different techniques have been used to study and understand brain mechanisms during deception. Moreover, efforts have been made to develop schemes that can detect and differentiate the deception and truth telling. In this paper, a functional near-infrared spectroscopy (fNIRS) based online brain deception decoding framework is developed. Deploying a dual-wavelength functional near-infrared spectroscopy, we interrogated sixteen sites around the forehead locations while eight able-bodied adults performed in separately deception scenarios and truth-telling scenarios. With the combination of preprocessed oxy-hemoglobin and deoxy-hemoglobin signals, we developed subject-specific classifiers using the support vector machine.
Kinetic Analysis of Several Variations of Push-Ups

Ebben, WP, Wurm, B, VanderZanden, TL, Spadavecchia, ML, Durocher, JJ, Bickham, CT, and Petushek, EJ. Kinetic analysis of several variations of push-ups. J Strength Cond Res 25(10): 2891–2894, 2011—Push-ups are a common and practical exercise that is used to enhance fitness, including upper body strength or endurance. The kinetic characteristics of push-ups and its variations are yet to be quantified. Kinetic quantification is necessary to accurately evaluate the training load, and thus the nature of the training stimulus, for these exercise variations. This study assessed the peak vertical ground reaction forces (GRFs) of push-up variations including the regular push-up and those performed with flexed knee, feet elevated on a 30.48-cm box, and a 60.96-cm box, and hands elevated on a 30.48-cm box and a 60.96-cm box. Twenty-three recreationally fit individuals (14 men, 9 women) performed each of the 6 push-up variations in a randomized order. Peak GRF and peak GRF expressed as a coefficient of subject body mass were obtained with a force platform. Push-ups with the feet elevated produced a higher GRF than all other push-up variations (p ≤ 0.05). Push-ups with hands elevated and push-ups from the flexed knee position produced a lower GRF than all other push-up variations (p ≤ 0.05). No gender differences in response to these push-up variations were found (p > 0.05). Additionally, subject height was not related to the GRF for any of the push-up conditions (p > 0.05) other than the condition where hands were elevated on a 60.96-cm box (p ≤ 0.05; r = 0.63). These data can be used to progress the intensity of push-ups in a program and to quantify the training load as a percentage of body mass.
Ethylene-vinyl acetate copolymer microspheres for controlled release of macromolecules.

A simple technique has been devised for preparing ethylene-vinyl acetate copolymer microspheres containing macromolecular drugs. Beads with good sphericity were formed by a simple extrusion process that can easily be repeated by any laboratory without special equipment. The extruded droplets gelled on immediate contact with cold ethanol in a dry ice-ethanol bath. The ethanol also served to remove the solvent and harden the microspheres as they warmed to room temperature. Release of bovine serum albumin followed the expected trends, i.e., initial linearity with the square root of time and faster release rates with greater drug loading.
The inflammatory response to CPB: the role of leukocyte filtration

Leukocyte activation is a significant component of the systemic inflammatory response to cardiopulmonary bypass (CPB). Various strategies have been developed aiming to reduce leukocyte activation and its deleterious effects on organ function after cardiac surgery. Leukocyte filtration aims to physically remove activated leukocytes from the circulation during CPB. The technique has been used since the mid-1990s but its efficacy in attenuating the effects of inflammatory response remains controversial. This article presents a review of published trials investigating the effects of leukocyte filtration on humans undergoing cardiac surgery.
Diversidad del platano de coccion consumido en Colombia

El estudio presentado permite conocer mejor le diversidad fisica (tamano del racimo, peso de manos, peso y forma de los dedos) asi como las diferencias de la propiedades funcionales de la pulpa, entre variedades y entre manos de un mismo racimo. Los promedios de peso, longitud y diametro intermedio de los dedos con cascara presentan una gran variabilidad con valores extremos de 107 g (Rollizo) hasta 720 g (Africa); para longitud entre 14 cm (Guineo) y 34 cm (Harton) y para diametro intermedio de 3.6 cm (Rollizo) hasta 6.3 cm (Hua Moa). Sin cascara, se observo una gran variabilidad para la pulpa con valores extremos de 60g (Rollizo) hasta 512 g (Africa), de 12 cm (Pelipita) hasta 30 cm (Africa) en longitud y 2.8 cm (FHIA 17 y Rollizo) hasta 5.6 cm (Hua Moa) de diametro. Las evaluaciones de las caracteristicas fisicas, con y sin cascara, permiten destacar las variedades con un gran potencial de industrializacion, como: FHIA 21, Dominico harton, Hua Moa, Guayabo, Africa y Harton. El porcentaje de cascara tambien difiere entre variedad de 26% hasta 49% sin tomar en cuenta el peso del vastago en los desechos. FHIA 20 y FHIA 17 tienen la proporcion mayor de cascara con 48 y 48.6%, respectivamente. Todas las variedades de uso industrial para el procesamiento se encuentran en el intervalo de 35 a 40% de proporcion de cascara: Harton, Dominico harton, Guayabo. Las variedades de menor proporcion de cascara son Africa y Hua Moa, con valores de 25% y 34% respectivamente. Los geles obtenidos a partir de harinas permiten poner en evidencia una variabilidad del comportamiento a la coccion de la diferentes variedades. La temperatura de inicio de la gelatinizacion, varia entre 68 hasta 75°C. Los platanos de coccion presentan la temperaturas mas altas de gelatinizacion: Guayabo, FHIA 25, Pelipita, Dominico harton, Africa, Cubano blanco y Harton, con 71.4, 72.1, 72.9, 72.9, 74.2, 75.4 y 75.7°C, respectivamente. La variabilidad de la viscosidad maxima por variedad, fluctua entre 1780 y 2640 centipoises (cP). Las variedades FHIA 25, Gross Michel, Rollizo, Dominico harton y Guineo tienen mayor viscosidad en la coccion. (Resume d'auteur)
Adaptive Nonlinear Control of Multiphase Synchronous Buck Power Converters

Abstract The problem of controlling multiphase synchronous buck power converters is considered. The aim is to regulate the output voltage of the converter and to ensure an adequate current sharing between its different channels. The control law is designed from the large-signal bilinear model (of the whole multichannels converter) using the backstepping technique. The obtained regulator is shown to meet its objectives namely an asymptotic stability of the closed-loop system, a tight output voltage regulation, an adequate current sharing and a good estimation of load resistor.
Chitosan Nanoparticles Cause Pre- and Postimplantation Embryo Complications in Mice1

ABSTRACT Embryo development is a complex and tightly controlled process. Nanoparticle injury can affect normal development and lead to malformation or miscarriage of the embryo. However, the risk that these nanoparticles may pose to reproduction is not clear. In this study, chitosan nanoparticles (CSNP) of near uniform size, in the range of 100 nm, were synthesized and confirmed by a particle size analyzer and transmission electron microscopy. Morulae-stage embryo exposure to CSNP during in vitro culture caused blastocyst complications that had either no cavity or a small cavity. Furthermore, CSNP-treated embryos showed lower expression of not only trophectoderm-associated genes but also pluripotent marker genes. When blastocysts developed in both media with and without CSNP were transferred to recipients, the percentage of blastocysts resulting in viable pups was significantly reduced. These detrimental effects are linked to the reduction of total cell numbers, enhanced apoptosis, and abnormal blastocoels forming at the blastocyst stage, indicating that CSNP treatment might have long-term adverse biological effects in view of pregnancy outcome.
Development of biocompatible and VEGF-targeted paclitaxel nanodrugs on albumin and graphene oxide dual-carrier for photothermal-triggered drug delivery in vitro and in vivo

In this study, we performed the characterization and synthesis of biocompatible and targeted albumin and graphene oxide (GO) dual-carrier paclitaxel (PTX) nanoparticles for photothermal-triggered tumor therapy. PTX absorbed on GO nanosheets as cores were coated with human serum albumin (HSA), following surface conjugation with monoclonal antibodies (mAb) against vascular endothelial growth factor (VEGF; denoted as mAbVEGF) via polyethylene glycol linker to form targeted nanoparticles (PTX-GHP-VEGF). The spherical nanoparticles were 191±5 nm in size with good stability and biocompatibility. GO functioned as the first carrier and a near infrared absorber that can generate photothermal effects under 5-minute 808-nm laser irradiation to thermal trigger the release of PTX from the second carrier HSA nanoparticles. The mechanism of thermal-triggered drug release was also investigated preliminarily, in which the heat generated by GO induced swelling of PTX-GHP-VEGF nanoparticles which released the drugs. In vitro studies found that PTX-GHP-VEGF can efficiently target human SW-13 adrenocortical carcinoma cells as evaluated by confocal fluorescence microscopy as well as transmission electron microscopy, and showed an obvious thermal-triggered antitumor effect, mediated by apoptosis. Moreover, PTX-GHP-VEGF combined with near infrared irradiation showed specific tumor suppression effects with high survival rate after 100 days of treatment. PTX-GHP-VEGF also demonstrated high biosafety with no adverse effects on normal tissues and organs. These results highlight the remarkable potential of PTX-GHP-VEGF in photothermal controllable tumor treatment.
Educational Pathways and Change in Crime Between Adolescence and Early Adulthood

Objectives: This article examines the relationship between intergenerational educational pathways and change in crime. Moreover, it examines the potential mediating roles of family and employment transitions, economic stressors, and social psychological factors. Method: Data from the National Longitudinal Study of Adolescent to Adult Health (N = 14,742) and negative binomial models are used to assess associations between educational pathways (i.e., upward, downward, and stable) and change in crime between adolescence and early adulthood. Selection effects are assessed with lagged dependent variables and controls for self-control, grades, and the Add Health Picture Vocabulary Test. Results: Intergenerational educational pathways are significantly associated with changes in crime. Downward educational pathways were predictive of increases in crime, whereas upward pathways were associated with decreases in crime. These associations were partly mediated by family transitions, and more strongly by economic stressors. These results were robust to controls for selection related variables. Conclusions: This study is among the first to examine the relationship between intergenerational educational pathways and crime in the United States. Both upward and downward changes in educational attainments were found to be significant for crime. These findings are notable given the continuing expansion of higher education as well as concerns regarding increasing stratification and downward mobility in the United States.
Hexammineruthenium(III) ion interactions with Z-DNA.

The hexamer duplex d(CGCGCA). d(TGCGCG) was crystallized with hexammineruthenium(III) ions in an orthorhombic space group; the crystals diffracted to 1.54 A resolution. Strong ion interactions with the adenine base induce a tautomeric shift from the amino to the imino form. Consequently, the A.T base pairing is disrupted. This structural study may be relevant to metal toxicity.
Understanding User Intention to Continue Sharing Knowledge in Virtual Communities

This paper introduces the research model of user intention to continue sharing knowledge in virtual communities. The model is built upon Batson’s framework of the act for the public good. Since the focus of this study is on the continued use of virtual communities, the model also takes user evaluation process into account and includes some important constructs (disconfirmation, satisfaction, and knowledge self-efficacy) to explain the continuance behavior. An online survey was conducted and a total of 315 completed questionnaires were collected. Among the 315 respondents, 60 respondents have participated and shared knowledge in a virtual community. The research model explains 62% of the variance. The results also provide strong support for the existing theoretical links, as well as for those newly hypothesized in this study. Implications for current investigation for both research and practice are provided.
The translocator protein as a drug target in Alzheimer’s disease

The translocator protein (TSPO) recently emerged as a potential drug target in Alzheimer’s disease (AD). This has been fuelled mainly by positron emission topography studies that show the upregulation of TSPO in AD, especially in relation to microgliosis and astrogliosis in amyloid-β and tau pathology. Although data as to the exact role of TSPO in AD is still inconclusive, TSPO appears to be involved in neuroinflammatory processes and AD has been shown to involve substantial inflammation. Therefore, further development and investigation of the pharmacological effect of TSPO ligands in AD pathology are warranted.
Plaque inhibition assay for drug susceptibility testing of influenza viruses

The relative antiviral activities of four drugs against contemporary strains of influenza A and B viruses were determined in Madin-Darby canine kidney cell monolayers with a plaque inhibition assay. This assay proved to be a reliable, rapid method of determining 50% inhibitory concentrations that correlated well with clinically achievable drug levels and the results of clinical trials. Contemporary strains of influenza A viruses (subtypes H1N1, H3N2, HSW1N1) required amantadine hydrochloride and rimantadine hydrochloride 50% inhibitory concentrations in the range of 0.2 to 0.4 microgram/ml, whereas 50% inhibitory concentrations ranged from approximately 50 to 100 micrograms/ml against influenza B viruses. Ribavirin was approximately 10-fold less active than amantadine hydrochloride against influenza A viruses, and the ribavirin 50% inhibitory concentrations against both influenza A and B viruses ranged from 2.6 to 6.8 micrograms/ml. Inosiplex had no antiviral activity in this test system.
Walk2Build: a GPS game for mobile exergaming with city visualization

In recent years public health has become of great concern, in particular the personal and national economic burden resulting from increasingly sedentary lifestyles. Sedentary lifestyles are particularly serious for young people who are badly affected by obesity problems that impact on their current and future lives. In an effort to tackle this problem games designers are designing games aimed at motivating people to take part in physical activities and have coined the term exergaming. This poster presents a mobile exergaming application developed in Android Java and HTML 5 targeting under-active teenagers and young adults. The objective is to encourage users to increase walking by an incremental number of steps each week. This is visualized as an isometric virtual town on a web browser (with rewards for achieving targets) and published on Facebook to exploit social networking in supporting users. This poster will examine the motivation behind our game, design decisions, our prototype and concludes with future plans.
Der Einfluß von Arbitrageuren auf die Preisführerschaft von Finanzmärkten

Die vorliegende Studie untersucht den Zusammenhang zwischen Arbitragetatigkeit und Preisfuhrerschaft eines Marktes anhand Kursanderungen des DAX und des DAX-Futures. Dem Gleichgewichtsmodell von Garbade/Silber (1983) folgend wird der Einflus (imperfekter) Arbitragetatigkeit auf die Lead-Lag-Struktur modelliert. Die empirischen Analysen zeigen einen signifikanten Einflus der Fehlbewertung zwischen Kassa- und Futuresmarkt auf die Preisfuhrerschaft, sofern die Fehlbewertung die Transaktionskosten ubersteigt. Weiterhin wird gefunden, das bei Uber- und Unterbewertungen des Futures unterschiedlich starke Anpassungsreaktionen der Preise auftreten. Schlieslich belegen die Resultate, das der Einflus der Arbitrageure auf die Preisfuhrerschaft mit abnemender Restlaufzeit des Futures starker wird. Insgesamt zeigen die Ergebnisse der Studie einen bedeutenden Einflus der Arbitrageure auf die Lead-Lag-Struktur zwischen Kassa- und Futuresmarkt. Das Verhalten der Arbitrageure scheint jedoch deutlich komplexer zu sein als in Garbade/Silber (1983) unterstellt.
MAM-RNN: Multi-level Attention Model Based RNN for Video Captioning

Visual information is quite important for the task of video captioning. However, in the video, there are a lot of uncorrelated content, which may cause interference to generate a correct caption. Based on this point, we attempt to exploit the visual features which are most correlated to the caption. In this paper, a Multi-level Attention Model based Recurrent Neural Network (MAM-RNN) is proposed, where MAM is utilized to encode the visual feature and RNN works as the decoder to generate the video caption. During generation, the proposed approach is able to adaptively attend to the salient regions in the frame and the frames correlated to the caption. Practically, the experimental results on two benchmark datasets, i.e., MSVD and Charades, have shown the excellent performance of the proposed approach.
Regional heterogeneity of human myocardial infarcts demonstrated by contrast-enhanced MRI. Potential mechanisms.

BACKGROUND Myocardial reperfusion is pivotal to the prognosis of patients with acute myocardial infarction. In these patients, coronary flow is generally assessed by angiography and tissue perfusion by tracer scintigraphy. This study was designed to examine whether magnetic resonance imaging (MRI) provides information on myocardial perfusion and damage beyond that supplied by angiography and thallium scintigraphy after acute myocardial infarction. METHODS AND RESULTS Twenty-two patients with recent myocardial infarction had ECG, echocardiography, coronary angiography, and fast contrast-enhanced MRI. Twelve patients also had exercise thallium scintigraphy. Time-intensity curves obtained from infarcted and noninfarcted regions were correlated with coronary anatomy and left ventricular function. Two perfusion patterns were observed in infarcted regions by comparison with the normal myocardial pattern. All patients but 1 had persistent myocardial hyperenhancement within the infarcted region up to 10 minutes after contrast. In 10 patients, this hyperenhanced region surrounded a subendocardial area of decreased signal at the center of the infarcted region associated with coronary occlusion at angiography, Q waves on ECG, and greater regional dysfunction by echocardiography. Moreover, the extent and location of the MRI abnormalities correlated well with the extent and location of the fixed single-photon emission computed tomography thallium defects. CONCLUSIONS Large human infarcts, associated with prolonged obstruction of the infarct-related artery, are characterized by central dark zones surrounded by hyperenhanced regions on MRI. Conversely, reperfused infarcts with less regional dysfunction have uniform signal hyperenhancement. The MRI hyperenhanced segment correlates well with the fixed scintigraphic defect in patients with acute myocardial infarction.
Genetics of the phage growth limitation (Pgl) system of Streptomyces coelicolor A3(2)

The phage growth limitation (Pgl) system, encoded by Streptomyces coelicolor A3(2), confers protection against the temperate bacteriophage φC31 and its homoimmune relatives. The Pgl phenotype is characterized by the ability of Pgl+ hosts to support a phage burst on initial infection but subsequent cycles are severely attenuated. Previously, two adjacent genes pglY and pglZ were shown to be required for Pgl. It had been shown by Southern blotting that Streptomyces lividans, a close relative of S. coelicolor and naturally Pgl−, does not contain homologues of pglYZ and that introduction of pglYZ into S. lividans is not sufficient to confer a Pgl+ phenotype. Moreover, the mechanism of the Pgl+↔ Pgl− phase variation associated with this phenotype is also not understood. Here we describe two novel genes, pglW and pglX, that were shown to be part of this system by complementation of Pgl− mutants and by insertional mutagenesis. pglW encodes a 169 kDa protein that includes putative motifs for both serine/threonine protein kinase activity and DNA binding. pglX encodes a 136 kDa protein with putative adenine‐specific DNA methyltransferase activity. pglW and pglX have overlapping stop‐start codons suggesting transcriptional and translational coupling. S1 mapping of transcripts initiating up‐stream of pglW indicated that, like pglYZ, pglWX is expressed in uninfected cultures. A homologue of pglX with 76% amino acid identity was identified in S. coelicolor, and insertional mutagenesis indicated that this gene was not required for the Pgl+ phenotype. Southern blots indicated that S. lividans does not contain homologues of pglW or pglX. A plasmid encoding pglWXYZ was able to confer the Pgl+ phenotype to S. lividans implying that these four genes constitute the whole system.
The raw, the cooked and the burnt: Interpretations of food and animals in the Hebridean Iron Age

The Iron Age settlement at Sollas, North Uist, Scotland, provides an unusually varied set of data relating to food and the role of animals in society. By comparing the evidence of food residues on pottery with animal remains from middens, foundation burials and cremations, structural patterns emerge which throw light on the relative status of domestic species. Sheep and cows are treated differently, with sheep being mainly huried, and cattle cremated. This patterning enables a speculative world view of the inhabitants to be constructed, and further analysis shows that mature cattle were classified differently from younger animals. It is suggested that these normally hidden structuring principles cause difficulties for the convenzantine to Ottoman times (ca. 10th-19th centuries A.D.) will be discussed, as well as the cultural changes in dining manners in that period. It is the intention of this paper to approach this evolution of wining and dining habits in an interdisciplinary perspective, in which archaeological data, textual sources and iconographical information will be combined.