Miracle-dz/UniFAR-FTUs huggingface dataset:
Social influence analysis in large-scale networks

In large social networks, nodes (users, entities) are influenced by others for various reasons. For example, the colleagues have strong influence on one's work, while the friends have strong influence on one's daily life. How to differentiate the social influences from different angles(topics)? How to quantify the strength of those social influences? How to estimate the model on real large networks? To address these fundamental questions, we propose Topical Affinity Propagation (TAP) to model the topic-level social influence on large networks. In particular, TAP can take results of any topic modeling and the existing network structure to perform topic-level influence propagation. With the help of the influence analysis, we present several important applications on real data sets such as 1) what are the representative nodes on a given topic? 2) how to identify the social influences of neighboring nodes on a particular node? To scale to real large networks, TAP is designed with efficient distributed learning algorithms that is implemented and tested under the Map-Reduce framework. We further present the common characteristics of distributed learning algorithms for Map-Reduce. Finally, we demonstrate the effectiveness and efficiency of TAP on real large data sets.
Numerical simulation of three-dimensional gas detonation

We investigate the characteristics of the three-dimensional detonation in an argon-diluted mixture of hydrogen and oxygen. The three-dimensional Euler equations with a simple chemical reaction model are used as the governing equations for the detonation problem. The spatial derivatives are evaluated using the WENO scheme, and the temporal derivative is calculated using the TVD Runge-Kutta method. It is verified that the detonation front is composed of incident shocks and Mach stems, joined at the lines of triple points by transverse waves. And the clear cellular structure is displayed by using a three-dimensional numerical visualization. The process of generating unburned gas pockets is shown by the spatial isosurface profiles of the reaction progress parameter in the exothermic period, and it is explained that the triple lines play a role of "shutter". Furthermore, the rectangles, enclosed by the triple lines, vary with the movement of the triple lines. Consequently, the evolution between the diagonal detonation and the rectangular detonation is realized.
On enhancing power conversion for heaving point absorbers with intelligent neuro-adaptive controller

This paper discusses a new method for enhanced power conversion with heaving point absorbers. The proposed scheme incorporates an intelligent neuro-adaptive controller for efficient heave velocity tracking. A novel algorithm is presented to generate the reference velocity signal by introducing a power loss control factor. It is observed through computer simulations that by increasing this factor improves the captured wave energy, which in turn enhances the converted electrical power. Overall, superior performance is achieved by the proposed methodology as opposed to the traditional passive control technique.
Acetylation of cyclophilin A is required for its secretion and vascular cell activation.

AIMS Cyclophilin A (CyPA) is a pro-inflammatory mediator involved in oxidative stress-related cardiovascular diseases. It is secreted from vascular smooth muscle cell (VSMC) in response to reactive oxygen species (ROS) in a highly regulated manner. Extracellular CyPA activates VSMCs and endothelial cells (ECs) promoting inflammation, cell growth, and cell death. Recently, it was shown that acetylated CyPA (AcK-CyPA) affects its function. We investigated the role of acetylation of CyPA for its secretion and signalling in vascular cells. METHODS AND RESULTS We used angiotensin II (Ang II) to create sustained ROS and found significantly increased AcK-CyPA in VSMC. Site-directed mutagenesis showed that lysines K82 and K125 were the predominant CyPA residues acetylated in response to Ang II. Importantly, acetylation of K82 and K125 were required for Ang II-mediated CyPA secretion. ROS inhibitors, Tiron, and N-acetylcysteine inhibited Ang II-induced intracellular CyPA acetylation and also AcK-CyPA secretion. Using secreted CyPA from wild type and K82/125R mutants expressed in transduced VSMC or in vitro acetylated recombinant CyPA, we showed that extracellular AcK-CyPA significantly increased pERK1/2, matrix metalloproteinase-2 activation, and ROS production in VSMC compared with non-acetylated CyPA. Moreover, extracellular AcK-CyPA increased adhesion molecule expression (VCAM-1 and ICAM-1) in EC, which promoted monocyte adhesion. CONCLUSIONS ROS-dependent acetylation of CyPA is required for the generation of extracellular CyPA. Acetylated extracellular CyPA regulates VSMC and EC activation, suggesting that inhibition of acetylation of CyPA may prevent the pathogenesis of oxidative stress-related cardiovascular diseases.
Resampling strategies to improve surrogate model‐based uncertainty quantification: Application to LES of LS89

Uncertainty quantification (UQ) is receiving more and more attention for engineering applications particularly from robust optimization. Indeed, running a computer experiment only provides a limited knowledge in terms of uncertainty and variability of the input parameters. These experiments are often computationally expensive, and surrogate models can be constructed to address this issue. The outcome of an uncertainty quantification study is, in this case, directly correlated to the surrogate's quality. Thus, attention must be devoted to the design of experiments to retrieve as much information as possible. This work presents 2 new strategies for parameter space resampling to improve a Gaussian process surrogate model. These techniques indeed show an improvement of the predictive quality of the model with high‐dimensional analytical input functions. Finally, the methods are successfully applied to a turbine blade large‐eddy simulation application: the aerothermal flow around the LS89 blade cascade.
δ-Generalized Labeled Multi-Bernoulli Filter Using Amplitude Information of Neighboring Cells

The amplitude information (AI) of echoed signals plays an important role in radar target detection and tracking. A lot of research shows that the introduction of AI enables the tracking algorithm to distinguish targets from clutter better and then improves the performance of data association. The current AI-aided tracking algorithms only consider the signal amplitude in the range-azimuth cell where measurement exists. However, since radar echoes always contain backscattered signals from multiple cells, the useful information of neighboring cells would be lost if directly applying those existing methods. In order to solve this issue, a new δ-generalized labeled multi-Bernoulli (δ-GLMB) filter is proposed. It exploits the AI of radar echoes from neighboring cells to construct a united amplitude likelihood ratio, and then plugs it into the update process and the measurement-track assignment cost matrix of the δ-GLMB filter. Simulation results show that the proposed approach has better performance in target’s state and number estimation than that of the δ-GLMB only using single-cell AI in low signal-to-clutter-ratio (SCR) environment.
Full recovery after prolonged resuscitation from cardiac arrest due to propafenone intoxication

Rationale: The prognosis of cardiac arrest (CA) induced by propafenone intoxication was thought to be very poor. The maximal duration of cardiopulmonary resuscitation (CPR) for propafenone induced CA is unknown. Patient concerns: We describe a case that was successfully resuscitated after prolonged CPR (totaling 340 minutes during one hospital visit) for propafenone intoxication without subsequent neurological sequela. Diagnoses: A previously healthy 36-year-old female who developed multiple and prolonged CAs after consuming 98 tablets of 50mg propafenone. The CPR duration of this case, to the best of our knowledge, is the longest of all existing propafenone-induced CPR events to still have full recovery. We also analyse the contributing factors to this successful CPR. Interventions: Sodium bicarbonate, inotropic drugs and pacemaker application did not prevent the occurrence of CA. A full recovery was eventually achieved after prolonged CPR with a mechanical CPR device, blood purification and other aggressive supportive treatments. Outcomes: Full recovery without neurological sequela. Lessons: Prolonged CPR including the application of mechanical CPR devices should be considered in propafenone-related CA, especially in young patients without significant comorbidities and delayed resuscitation.
Association Between Intimate Partner Violence and Breastfeeding Duration: Results From the 2004-2014 Pregnancy Risk Assessment Monitoring System

Background: Intimate partner violence is a major public health problem that disproportionately affects women. Current literature investigating the relationship between intimate partner violence and breastfeeding is inconsistent. Research aim: This study aims to investigate the relationship between physical intimate partner violence that occurs in the preconception or prenatal period and any breastfeeding duration. Methods: Data from the retrospective, cross-sectional 2004-2014 Pregnancy Risk Assessment Monitoring System were analyzed (N = 195,264). The outcome, breastfeeding duration, was categorized as never breastfed, breastfed 8 weeks or less, and breastfeed more than 8 weeks. Multinomial logistic regression was used to obtain crude and adjusted odds ratios and 95% confidence intervals. Results: Approximately 6% (n = 11,766) of survey respondents reported preconception and/or prenatal intimate partner violence, and 36.3% (n = 67,667) of women reported never breastfeeding. The odds of discontinuing breastfeeding before 8 weeks were 18% higher among women who reported experiencing abuse 12 months before pregnancy compared with women who did not report intimate partner violence (adjusted odds ratio = 1.18; 95% confidence interval [1.01, 1.37]). All other estimates showed an overlapping 95% confidence interval. Conclusion: Breastfeeding is essential in improving maternal and child health; however, women in abusive relationships may face additional barriers to breastfeeding. Further research is needed to better understand the impact of violence on breastfeeding behaviors to inform healthcare practices and interventions.
INVITED: A Modular Digital VLSI Flow for High-Productivity SoC Design

A high-productivity digital VLSI flow for designing complex SoCs is presented. The flow includes high-level synthesis tools, an object-oriented library of synthesizable SystemC and C++ components, and a modular VLSI physical design approach based on fine-grained globally asynchronous locally synchronous (GALS) clocking. The flow was demonstrated on a 16nm FinFET testchip targeting machine learning and computer vision.
ОПТИЧЕСКИЕ И ОПТИКО - ЭЛЕКТРОННЫЕ ПРИБОРЫ И СИСТЕМЫ

Machine vision systems are a dynamically developing field of robotics. They give the ability to detect, visualize, track and recognize objects to the manufacturing and controlling cyberphysical systems. The use of such systems along with modern image processing algorithms allows shifting part of the operator's routine duties to a robotic system, in accordance with the industry 4.0 paradigm. An important property of the machine vision system is the resolving power, which can be estimated using various parameters and characteristics. The goal of this paper is to compare existing resolution measurement methods for the machine vision systems and to discuss their advantages and drawbacks.
Impact of paternal deployment to the conflicts in Iraq and Afghanistan and paternal post-traumatic stress disorder on the children of military fathers

Background Little is known about the social and emotional well-being of children whose fathers have been deployed to the conflicts in Iraq/Afghanistan or who have post-traumatic stress disorder (PTSD). Aims To examine the emotional and behavioural well-being of children whose fathers are or have been in the UK armed forces, in particular the effects of paternal deployment to the conflicts in Iraq or Afghanistan and paternal PTSD. Method Fathers who had taken part in a large tri-service cohort and had children aged 3–16 years were asked about the emotional and behavioural well-being of their child(ren) and assessed for symptoms of PTSD via online questionnaires and telephone interview. Results In total, 621 (67%) fathers participated, providing data on 1044 children. Paternal deployment to Iraq or Afghanistan was not associated with childhood emotional and behavioural difficulties. Paternal probable PTSD were associated with child hyperactivity. This finding was limited to boys and those under 11 years of age. Conclusions This study showed that adverse childhood emotional and behavioural well-being was not associated with paternal deployment but was associated with paternal probable PTSD. Declaration of interest N.T. F. is a trustee of the Warrior Programme, a charity supporting ex-service personnel and their families. She is also a member of the Independent Group Advising on the Release of Data (IGARD). S.W. is a trustee of Combat Stress, a charity supporting ex-service personnel and their families, and President of the Royal Society of Medicine. S.W. is partially funded by the National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Emergency Preparedness and Response at King's College London in partnership with Public Health England (PHE), in collaboration with the University of East Anglia and Newcastle University.
Effects of DHA- Rich n-3 Fatty Acid Supplementation on Gene Expression in Blood Mononuclear Leukocytes: The OmegAD Study

Background Dietary fish oil, rich in n-3 fatty acids (n-3 FAs), e.g. docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), regulate inflammatory reactions by various mechanisms, e.g. gene activation. However, the effects of long-term treatment with DHA and EPA in humans, using genome wide techniques, are poorly described. Hence, our aim was to determine the effects of 6 mo of dietary supplementation with an n-3 FA preparation rich in DHA on global gene expression in peripheral blood mononuclear cells. Methods and Findings In the present study, blood samples were obtained from a subgroup of 16 patients originating from the randomized double-blind, placebo-controlled OmegAD study, where 174 Alzheimer disease (AD) patients received daily either 1.7 g of DHA and 0.6 g EPA or placebo for 6 months. In blood samples obtained from 11 patients receiving n-3 FA and five placebo, expressions of approximately 8000 genes were assessed by gene array. Significant changes were confirmed by real-time PCR. At 6 months, the n-3 FAs group displayed significant rises of DHA and EPA plasma concentrations, as well as up- and down-regulation of nine and ten genes, respectively, was noticed. Many of these genes are involved in inflammation regulation and neurodegeneration, e.g. CD63, MAN2A1, CASP4, LOC399491, NAIP, and SORL1 and in ubiqutination processes, e.g. ANAPC5 and UBE2V1. Down-regulations of ANAPC5 and RHOB correlated to increases of plasma DHA and EPA levels. Conclusions We suggest that 6 months of dietary n-3 FA supplementation affected expression of genes that might influence inflammatory processes and could be of significance for AD. Trial Registration ClinicalTrials.gov NCT00211159
Development of a brief version of the Autism Detection in Early Childhood

While autism spectrum disorder screening tools provide a useful resource for practitioners, the reality is they are underused. The justifications often provided include the time required for administration and the training involved. A brief tool with good psychometric properties that require minimal training is required. This study examined the development and the psychometric properties of a brief version of the Autism Detection in Early Childhood. The data showed the potential of the brief version of Autism Detection in Early Childhood for screening children age 12–36 months. Our dataset comprised 106 Diagnostic and Statistical Manual of Mental Disorders, 5th edition autism spectrum disorder, 86 non-typical development and 78 typical development participants age 12–36 months. Analyses comparing autism spectrum disorder and non-typical development groups supported the use of five critical items (i.e. response to name, social smiling, gaze switch, response to verbal command and use of gestures) to form the brief version Autism Detection in Early Childhood. The brief version of Autism Detection in Early Childhood’s optimal cutoff score of 4 had sensitivity of 0.81, specificity of 0.78, positive predictive value of 0.81 and negative predictive value of 0.78. However, the results would need to be viewed as preliminary given the nature of the study sample and the findings might not be generalisable to samples with higher levels of cognitive functioning.
Efficient Embedding of Scale-Free Graphs in the Hyperbolic Plane

Hyperbolic geometry appears to be intrinsic in many large real networks. We construct and implement a new maximum likelihood estimation algorithm that embeds scale-free graphs in the hyperbolic space. All previous approaches of similar embedding algorithms require at least a quadratic runtime. Our algorithm achieves quasi-linear runtime, which makes it the first algorithm that can embed networks with hundreds of thousands of nodes in less than one hour. We demonstrate the performance of our algorithm on artificial and real networks. In all typical metrics, such as log-likelihood and greedy routing, our algorithm discovers embeddings that are very close to the ground truth.
Trends in thyroid cancer incidence and mortality in Central Serbia, 1999-2014.

INTRODUCTION Thyroid cancer (TC) is the most common malignant disease of the endocrine system. The incidence of the TC has been increasing worldwide, especially in female population. However, mortality from TC is low in both males and females. The objective of the paper was to determine and to analyze incidence and mortality trends of TC in males and females in the central Serbia in the period 1999-2014. METHOD In this descriptive study data from the Serbian Cancer Registry were used. Crude and age-standardized rates (ASRs) of incidence and mortality were calculated. Trend and annual percentage change (APC) of the incidence and mortality rate with corresponding 95% confidence intervals (CI) were calculated by performing Joinpoint regression analyses. RESULTS A total number of new cases of TC was 3113. TC was diagnosed in 2343 females and 770 males (female-to-male ratio, 3:1). A total number of fatal cases was 770 (while 504 female and 266 male died from TC, female-to-male ratio, 1.9:1). TC was not common before 30 years of age. The highest incidence was recorded both in males and females aged 50-59. Joinpoint regression analysis showed the statistically significant increase of ASRs of TC incidence in males in 1999-2014 period with APC 6.2% (95% CI: 4.2-8.3, p < 0.001) and there was also significant increase of ASRs of TC incidence in females in the same study period with a APC 6.1% (95% CI: 4.2-8.0, p < 0.001). Joinpoint regression analysis showed an insignificant increase of ASRs of TC mortality in males with APC 2.4% (95% CI: -0.5-5.5, p = 0.1). There was an insignificant decrease of ASRs of TC mortality in females with APC -1.3% (95% CI: -4.4-1.9, p = 0.4). CONCLUSION The increasing trend of age-standardized incidence rates of TC both in males and females and decreasing trend of age-standardized mortality rates during the observed period were registered. Females had higher age-standardized incidence and mortality rates than males. Female to male ratio of incidence was 3:1 and for mortality 1.9:1. Measures of primary and secondary prevention are needed.
Compassionate Values as a Resource during the Transition to College: Quiet Ego, Compassionate Goals, and Self-Compassion.

This study examined the unique contributions of compassion-related values and skills on stress and life satisfaction in two samples of first-year college students. Quiet ego, a measure of a compassionate self-identity, was associated with using relatively more compassionate interpersonal goals relative to selfimage goals. Self-compassion and, to a lesser extent, self-control showed similar patterns of relative goal use. We tested a path model of hypothesized relationships in Sample 1 and confirmed the model in Sample 2. Quiet ego characteristics were associated with greater life satisfaction. Furthermore, these relationships were at least partially mediated by the relationships between self-compassion, self-control, and perceived stress. Discussion focuses on the potential importance of studentfocused interventions that cultivate compassionate goals and a compassionate self-identity as a resource during the transition to college. The transition to college can be a particularly stressful time in a young person’s life (Dyson & Renk, 2006; Pryor, Hurtado, DeAngelo, Paluki Blake, & Tran, 2010; Ross, Neibling, & Heckert, 1999). Between 30% and 55% of college students report greater than average levels of stress (ACHA, 2014; Regehr, Glancy, & Pitts, 2013), with depression and anxiety the most common reactions. Several individual-difference factors have been identified that positively influence appraisal and the coping processes needed to manage college-related stress (DeLongis, Folkman, & Lazarus, 1988; Lazarus, 2001), including optimism, self-esteem, self-efficacy, emotional intelligence, and hardiness as well as interpersonal resources such as social support and a sense of belonging (Aspinwall & Taylor, 1992; Costa, Ripoll, Sanchez, & Carvalho, 2013; Hagerty & Williams, 1999; Hagerty, Williams, Coyne, & Early, 1996; Jiang et al., 2014; Knowlden, Sharma, Kanekar, & Atri, 2012; Lian, Sun, Ji, Li, & Peng, 2014; Pritchard, Wilson, & Yamnitz, 2007; Walton & Cohen, 2011). Like most transitions, the transition to college is characterized by uncertainty, which is associated with increased self-evaluative activity (Wayment & Taylor, 1995). Such activity may include thoughts and feelings that could be characterized as selffocused (e.g., Am I smart enough? Am I popular enough? Do I fit in? ). Maladaptive forms of self-focus are associated with negative affect and psychological distress