Miracle-dz/UniFAR-FTUs huggingface dataset:
Knowledge of and management attitude regarding dentin hypersensitivity among dentists from a West African country.

AIM The aim of the present study was to assess knowledge of, and management attitude of dentists regarding dentin hypersensitivity. MATERIALS AND METHODS The study involved all the dentists from private and public sectors, exerting in Senegal. The following data were requested from the surveyed dentists using an anonymous questionnaire; sociodemographics (i.e. age, gender, area of activity, etc.) and knowledge on triggering factor, type of pain, diagnosis, preventive and curative procedures. RESULTS Out of the 238 dentists who received the questionnaire, 68.9% returned properly filled forms. They were 116 males and 48 females with a mean age of 41.99 ± 8.50 years. Eighty three percent of the participants had a good understanding of the characteristics of pain related to DH and 92% recognized chemical and thermal stimuli as triggering factor while mechanical stimulus was not evoked. Many responders (90.9%) did not have any idea of the mechanism for pain transmission across the dentin. Regarding diagnosis technique, 68% use mechanical stimuli to elicit DH pain. Regarding management procedure, the use of desensitizing tooth paste is the mostly chosen option followed by professional topical application of fluoride. More than 1/3rd of the surveyed dentists confess resorting to root canal to manage DH. CONCLUSION We recommend incorporation of basic science knowledge on orofacial pain and competencies to manage painful conditions like dentin hypersensitivity. Also, health regulatory institutions should make continuing dental education a requirement to preserve the dental licensure.
Effect Analysis of Regional MF Industry in Three Economic Zones for Regional Economy Growth

This article adopts logistic model to confirm the function between regional MF industry and regional economy increase.And taking three economic zones as example,adopts margin and elasticity analysis to define the increasing number of regional economics resulted in regional MF industry.It indicates that the contribution for each regional MF industry to the regional economy growth is different from the growth stage of regional MF.Aiming at the different growth stage,decision-maker should make right industry policies to accelerate the development of regional MF.
Gender Classification of Chinese Weibo Users

User profiles describe users with many personalized features, which help us recognize and understand users. Gender classification is one of the fundamental research tasks on user profiles. Recently there are few studies on gender classification of Chinese micro-blog authors. In this paper we present an efficient gender classification model to predict the gender values of specified users crawled from Sina Weibo, a Chinese micro-blog service. We also discuss the difference between several classification models and algorithms, then try to optimize our solutions. Finally, we present the experimental results and examine the behavior and scalability of our model, and validate our approach by examining different classifiers over a large dataset.
A REVIEW: POTENSI RISIKO PADA SUPPLY CHAIN RISK MANAGEMENT

Supply Chain Risk Management merupakan risiko yang terjadi pada aliran produk, informasi, bahan baku sampai pengiriman produk akhir yang mengancam keseluruhan supply chain dari pemasok awal hingga sampai konsumen. Sedangkan Supply chain disruptions (gangguan rantai pasok) adalah peristiwa tak terencana yang terjadi dalam rantai pasok yang bisa mempengaruhi aliran bahan dan komponen. Kejadian risiko yang terjadi didalam supply chain telah banyak dilakukan oleh beberapa peneliti sehingga perlu dilakukan review untuk mengetahui potensi risiko yang terjadi pada supply chain. Risiko yang terjadi pada supply chain berdasarkan hasil penelitian sebelumya terdapat 120 jenis risiko. Kesamaan risiko yang terjadi pada supply chain menghasilkan 17 jenis risiko yang sama pada supply chain dan terdapat 3 risiko yang sering terjadi yaitu risiko demand, keterlambatan bahan baku, Bencana alam (discruption), sedangkan 14 risiko lainnya yaitu , kwalitas supplier, kwalitas produk, sistem informasi, harga, suplai, produk rusak digudang, finansial, ketergantungan supplier, penundaan, kapasitas produksi, persediaan, kekurangan bahan baku, selisih stok dan politik. Adapun mitigasi yang dapat dilakukan dalam mengatasi gangguan supply chain ada 9 strategi yaitu: postponement, strategy stock, flexible supply base. make and buy, economic supply incentives, flexible transportation. revenue management via dynamic pricing and promotion, assortment planning. silent product rollover. Kata Kunci: Potensi, Supply Chain, Risk Management
Strifes of the frontier: an assessment of Acacia mearnsii related park-community conflicts in the Golden Gate Highlands National Park, South Africa

Abstract This study coins the “reality-worldview” framework to examine park-community conflicts arising from the expediency to protect the environmental integrity of a South African national park from bio-invasion. The study used remote sensing data to investigate the state of vegetation cover along the northern fringes of the park and an adjacent communal grazing area to determine differences in plant based resource endowments between the two areas. The study also involved the discriminant analysis of survey responses from park officials and local communities regarding perceptions about the environmental impacts of Acacia mearnsii invasion, as well as how the species spreads and how the species can be controlled. The objective of the study was to assess park-community conflicts arising from initiatives to limit community access to park resources on the justification of the need to prevent the invasion of the park by A. mearnsii. The study concludes that even though uncontrolled movement of people and livestock creates the obvious danger of invasion of the park by the species, the extent to which the species is viewed as an environmental threat depends on the “worldviews” of the stakeholders, the bridging of which can only be achieved through negotiation, environmental awareness and education campaigns and provision of training in conflict resolution to the belligerents.
Comparative Secretome Analysis of Ralstonia solanacearum Type 3 Secretion-Associated Mutants Reveals a Fine Control of Effector Delivery, Essential for Bacterial Pathogenicity*

Ralstonia solanacearum, the causal agent of bacterial wilt, exerts its pathogenicity through more than a hundred secreted proteins, many of them depending directly on the functionality of a type 3 secretion system. To date, only few type 3 effectors have been identified as required for bacterial pathogenicity, notably because of redundancy among the large R. solanacearum effector repertoire. In order to identify groups of effectors collectively promoting disease on susceptible hosts, we investigated the role of putative post-translational regulators in the control of type 3 secretion. A shotgun secretome analysis with label-free quantification using tandem mass spectrometry was performed on the R. solanacearum GMI1000 strain. There were 228 proteins identified, among which a large proportion of type 3 effectors, called Rip (Ralstonia injected proteins). Thanks to this proteomic approach, RipBJ was identified as a new effector specifically secreted through type 3 secretion system and translocated into plant cells. A focused Rip secretome analysis using hpa (hypersensitive response and pathogenicity associated) mutants revealed a fine secretion regulation and specific subsets of Rips with different secretion patterns. We showed that a set of Rips (RipF1, RipW, RipX, RipAB, and RipAM) are secreted in an Hpa-independent manner. We hypothesize that these Rips could be preferentially involved in the first stages of type 3 secretion. In addition, the secretion of about thirty other Rips is controlled by HpaB and HpaG. HpaB, a candidate chaperone was shown to positively control secretion of numerous Rips, whereas HpaG was shown to act as a negative regulator of secretion. To evaluate the impact of altered type 3 effectors secretion on plant pathogenesis, the hpa mutants were assayed on several host plants. HpaB was required for bacterial pathogenicity on multiple hosts whereas HpaG was found to be specifically required for full R. solanacearum pathogenicity on the legume plant Medicago truncatula.
GrC-based real-time fault predictive diagnosis method

Traditional diagnostic systems generally are off-line and confirmatory. When abnormal variables occur, they cannot provide predictive diagnosis and maintenance suggestions in time. So the anomaly may be further accumulated and lead to more serious faults. This paper proposes a real-time fault predictive diagnosis method, which is based on granular reduction algorithm and granular similarity calculation. By using this method, the predictive fault diagnosis of a real-time system can be changed into a set of simple mathematical operations. Finally, the validity and feasibility of the method are illustrated with a real example.
Noninvasive determination of cardiac output by a modified acetylene rebreathing procedure utilizing mass spectrometer measurements.

A modified acetylene rebreathing technique for measuring cardiac output has been developed utilizing a mass spectrometer for measuring gas concentrations. Helium serves as an indicator of mixing and system volume. The disappearance rate of acetylene is proportional to pulmonary capillary blood flow, which is taken as an index of cardiac output. The method also provides an estimate of pulmonary tissue volume. The technique was assessed by comparing 22 simultaneous acetylene and dye-dilution cardiac outputs measured at rest and during exercise in six healthy subjects. There was no significant difference between the mean acetylene and dye-dilution cardiac output values (11.5 l/min vs. 11.24 l/min, respectively). The correlation coefficient was 0.94 and the S.E. M. difference was 0.53 l. The effect of the procedure on cardiac output was evaluated in a separate study of six subjects. There was a significant positive correlation between respiratory rate and cardiac output; but the magnitude of this effect was small, indicating that accurate measurements may be made at spontaneous respiratory rates.
Botnet Detection Method Analysis on the Effect of Feature Extraction

Botnets have been one of the most threatening risks against cybersecurity since 2003. Their aggressiveness and destructiveness affect the proper functioning of network directly. It is quick-witted for them to make use of changing communication mode and recruiting new members to evade detection and even reduce losses once detected. However, there still exist some hints to find and locate zombies even though their stealthiness and variability. To this end, one of the main concerns in designing a botnet detection system is how and which discriminating features to get. Hence, the feature extration becomes a key issue for the purpose of developing a powerful botnet detection system. In this work, we utilize three machine learning algorithms to explore which feature extration method is better between Netmate and Tranalyzer only using packet header information in case of privacy problems. From this perspectives, We conduct a series of experiments on two public botnet data sets and then perform some analyses of the laboratory results.
Alteration of lysophosphatidylcholine content in low density lipoprotein after oxidative modification: relationship to endothelium dependent relaxation.

OBJECTIVE The aim was to examine the formation of lipid peroxidation products and the alteration in phospholipid content in low density lipoprotein (LDL) after oxidative modification by CuSO4, and subsequently, to determine the ability of the modified LDL to impair endothelium dependent relaxation in rat aortic rings. METHODS Blood samples were obtained from normal human volunteers. LDL was prepared by sequential ultracentrifugation and it was oxidatively modified in the presence of 5 microM CuSO4. Lipid peroxidation products (thiobarbituric acid reactive substances, TBARS), and alterations in electrophoretic mobility and phospholipid content were determined in normal (native) and oxidised LDL. Endothelium dependent relaxation was produced by acetylcholine (10(-8)-10(-5) M) in phenylephrine precontracted rat aortic rings. RESULTS LDL incubated for 24 h with 5 microM CuSO4 at 20 degrees C and 37 degrees C with constant agitation displayed higher amounts of TBARS than the respective native LDL. While the amounts of TBARS in LDL modified at 20 degrees C and 37 degrees C were similar, the former condition resulted in statistically smaller changes of phospholipid contents. LDL with higher lysophosphatidylcholine content showed greater impairment of endothelium dependent relaxation in rat aortic rings than LDL with lower lysophosphatidylcholine content. CONCLUSIONS The raised lysophosphatidylcholine level in oxidatively modified LDL was related to the ability of the LDL to impair endothelium dependent relaxation. However, lipid peroxidation products assessed by TBARS did not relate to the phospholipid changes in LDL and therefore cannot be used to predict the vascular effects of LDL after oxidative modification.
Switching Rate and Dwell Time in M-of-N Selection Diversity

Many investigations of hybrid selection (HS) diversity assume maximal ratio combining (MRC) of the selected branches. However, a coherent detector needs to dwell on the received signal for some time before it can produce accurate channel estimates for fading compensation, a requirement that appears inconsistent with the branch switching that occurs in a selection diversity receiver. Motivated by this observation, we derive in this letter analytical results on the switching rate and average dwell time of a selection diversity receiver where M out of a total of N independent branches are selected for combining. We show that the switching rate can be many times the Doppler frequency, while the average dwell time can be a small fraction of the reciprocal Doppler frequency. The brevity of the dwell times suggests difficulty in obtaining channel state information, which in turn calls into question performance analyses of idealized HS/MRC structures. Our results also suggest that HS/MRC should be frame-based, rather than continuously acting in time
Nurses' opportunistic interventions with patients in relation to smoking.

AIM This paper reports a study exploring nurses' provision of opportunistic health education on smoking for hospital patients. BACKGROUND Smoking cessation guidelines recommend assessment of patients' smoking habits and provision of smoking cessation advice when possible, and highlight the importance of the role of nurses in health promotion and health education. In the past, nurses have been criticized for lack of knowledge, skills and confidence in relation to health education and the perception that it is additional to, rather than integrated with, nursing care. METHODS A qualitative case study design was selected to explore the health education practice of 12 nurses working in acute wards in three general hospitals in Scotland. Data were collected in 2000 through non-participant observation, semi-structured interviews and the use of a radio-microphone to record nurse-patient interactions. The data analysis was guided by four key elements of health education practice: 'the teachable moment', 'readiness to learn', 'the provision of health information' and 'oral communication'. FINDINGS Smoking was part of the nurses' agenda, as most recognized opportunities to introduce health education on smoking during nursing care, suggesting a tentative move towards the integration of health education with nursing care. Evidence from patients' interactions indicated ample opportunity for nurses to provide smoking-related health information. However, the content of nurses' interactions on smoking was variable, with some limited by poor communication skills and inadequate knowledge of smoking and smoking cessation. The context of the interactions was also important in understanding some of the restrictions on conversational progress. CONCLUSIONS Nurses require the knowledge and skills to perform a health education role, and the inclusion of smoking cessation guidelines in nursing curricula would contribute to this. Where patients are in hospitals for short periods of time, opportunistic health education on smoking needs to be introduced as the basis for more specialist intervention.
Immunity against Helicobacter pylori: Significance of Interleukin-4 Receptor α Chain Status and Gender of Infected Mice

ABSTRACT Vaccination of interleukin-4 (IL-4) receptor α (IL-4Rα) chain-deficient BALB/c mice with Helicobacter pylori urease and cholera toxin or with urease-expressing, live attenuatedSalmonella enterica serovar Typhimurium cells revealed that protection against H. pylori infection is independent of IL-4- or IL-13-mediated signals. A comparison of male and female mice suggests a sexual dimorphism in the extent of bacterial colonization that is particularly evident in the absence of the IL-4Rα chain.
The effects of childhood maltreatment on brain structure in adults with eating disorders

Abstract Objectives: Childhood maltreatment is a non-specific risk factor for eating disorders (EDs). However, so far, no study has assessed the impact of childhood maltreatment on brain structure of adults with EDs. Therefore, we investigated brain area volumes and fibre tract integrity of childhood maltreated (Mal) and non-maltreated (noMal) patients with EDs. Methods: Thirty-six ED women and 16 healthy women underwent an MRI scan, including acquisition of a diffusion tensor imaging (DTI) sequence and a high-resolution T1-weighted scan. ED participants were classified as Mal (18 patients) or noMal (18 patients) according to their childhood exposure to traumatic events assessed by the Childhood Trauma Questionnaire (CTQ). Results: Significantly reduced grey matter volume was detected in the right paracentral lobule and in the left inferior temporal gyrus of Mal patients. DTI analyses revealed reduced white matter integrity in the corpus callosum, internal capsule, posterior thalamic radiation, longitudinal fasciculus and corona radiata of Mal patients. Negative correlations emerged between white/grey matter changes and CTQ emotional and physical neglect scores. Conclusions: These results show that childhood trauma affects the integrity of brain structures modulating brain processes, such as reward, taste and body image perception, which play a fundamental role in the psychopathology of EDs.
Health years equivalents as a measurement of preferences for dental interventions.

OBJECTIVE To test the feasibility and importance of measuring preferences among treatment choices using Healthy Years Equivalents (HYE). DESIGN Development of scenarios for alternative approaches to caries treatment. Completion of category rating and standard gamble questions elicited in personal interviews. SETTING The provision of dental care to children in a public-funded dental health clinic. PARTICIPANTS Random sample of the adult population of Hamilton, Ontario. MAIN OUTCOME MEASURES The percentage of the sample unable to complete the interviews, time taken to perform interviews, ease of understanding of interviews, correlation between rank ordering and HYE scores. RESULTS Ninety-six per cent of the sample were able to complete the HYE exercise. Inconsistencies between HYE scores and rank orders implying preference reversal occurred in 6% of those completing HYE scores for the two scenarios. The additional time taken by the HYE was of the order of 17 minutes but increased with the age of the subject. Where problems occurred, they were related to the method of measurement or the sensitivity of the chosen scale as opposed to additional requirements of the HYE. There was some evidence that HYEs and QALYs produced different scores even in the context of chronic constant health states. CONCLUSIONS HYEs are a feasible and important practical method of measuring preferences among interventions. Alternative utility-based approaches, such as willingness to pay, may be required to detect differences in modest improvements in temporary health states.
Organ preservation solutions increase endothelial permeability and promote loss of junctional proteins.

OBJECTIVE To investigate the effects of the organ preservation solutions UW and Plegisol on endothelial permeability; occludin and vascular endothelial (VE)-cadherin content in human umbilical vein endothelial cells (HUVEC); and junctional localization of these proteins after exposure to these solutions. SUMMARY BACKGROUND DATA Organ preservation for transplantation is limited by several challenges, including loss of tissue function, tissue injury, and tissue edema. Occludin and VE-cadherin are responsible for maintaining and regulating the endothelial solute barrier. Several studies have noted organ edema and dysfunction with preservation, as well as gaps between endothelial cells suggesting that disorganization of junctional proteins (e.g., occludin and VE-cadherin) is responsible for interstitial edema. METHODS HUVEC monolayers were treated with 4 degrees C UW and Plegisol for 3 and 6 hours and then reperfused with normal buffer. Permeability was examined using FITC-dextran tracer during the reperfusion phase. Occludin and VE-cadherin content at different time points was measured by Western blotting. Treated groups were also examined by immunofluorescence for occludin, VE-cadherin, and F-actin. RESULTS Compared with untreated controls, cold preservation for 3 and 6 hours increased endothelial permeability after rewarming, which appears to depend on the duration of cold exposure. Monolayers exposed to 3 hours of cold preservation did not have increased permeability in the first hour after rewarming but had significantly increased permeability after the first hour and all subsequent time points. Monolayers exposed to 6 hours of cold preservation had increased permeability after the first hour and at all later time points. Western blotting demonstrated that occludin content was decreased to a similar extent with all solutions after 3 hours of cold preservation. Six hours of cold preservation in Plegisol reduced the occludin content significantly compared with UW and control. VE-cadherin content was unchanged after 3 hours of cold preservation but was dramatically reduced in all groups at 6 hours. Immunofluorescent staining demonstrated junctional gap formation and discontinuous staining of occludin and VE-cadherin with all cold preservation protocols; changes in F-actin organization were observed at 3 and 6 hours after cold preservation. CONCLUSION The changes in occludin, VE-cadherin, and F-actin content and organization and increased permeability associated with cold storage demonstrate that alterations of the tight and adherens junctions may underlie organ edema associated with cold organ preservation. These data also suggest that novel strategies to maintain the content and integrity of endothelial junctional proteins may provide an important therapeutic avenue for organ preservation.