Miracle-dz/UniFAR-FTUs huggingface dataset:
The Privilege of Being a Therapist: A Fresh Perspective from Intrapsychic Humanism on Caregiving Intimacy and the Development of the Professional Self *

The internal world of the clinical social worker looks very different when seen from the perspective of intrapsychic humanism, a comprehensive psychodynamic psychology (Pieper & Pieper, 1990). Adopting this view of development and treatment can remedy one of the most perplexing and pressing dilemmas facing even the most conscientious and dedicated mental health professional – the vulnerability to what Hiratsuku termed “compassion fatigue” (1991) — to feeling stuck with an unrewarding daily clinical experience. The following discussion offers social workers three guidelines that will transform their clinical experience and make it exciting and fulfilling: how to recognize clients' aversive reactions to pleasure; how to hear both the process and content meanings of a client's communications; and how to distinguish between the social worker's personal and caregiving motives. These principles will help all social workers, including those doing brief treatment, long-term treatment, school counseling, and traditional casework.
A highly conserved tryptophan residue in the fourth transmembrane domain of the A1 adenosine receptor is essential for ligand binding but not receptor homodimerization

Dimerization between G protein‐coupled receptors (GPCRs) is a clearly established phenomenon. However, limited information is currently available on the interface essential for this process. Based on structural comparisons and sequence homology between rhodopsin and A1 adenosine receptor (A1R), we initially hypothesized that four residues in transmembrane (TM) 4 and TM5 are involved in A1R homodimerization. Accordingly, these residues were substituted with Ala by site‐directed mutagenesis. Interestingly, the mutant protein displayed no significant decrease in homodimer formation compared with wild‐type A1R, as evident from coimmunoprecipitation and BRET2 analyses (improved bioluminescence resonance energy transfer system offered by Perkin‐Elmer Life Sciences), but lost ligand binding activity almost completely. Further studies disclosed that this effect was derived from the mutation of one particular residue, Trp132, which is highly conserved among many GPCRs. Confocal immunofluorescence and cell‐surface biotinylation studies revealed that the mutant receptors localized normally at transfected cell membranes, signifying that loss of ligand binding was not because of defective cellular trafficking. Molecular modeling of the A1R‐ligand complex disclosed that Trp132 interacted with several residues located in TM3 and TM5 that stabilized agonist binding. Thus, loss of interactions of Trp with these residues may, in turn, disrupt binding to agonists. Our study provides strong evidence of the essential role of the highly conserved Trp132 in TM4 of adenosine receptors.
La surveillance maritime en imagerie radar bistatique: théorie, simulation, contribution à la détection automatique du sillage des navires. (Marine surveillance with bistatic radar: theory, simulation, contribution to computer-aided ship wakes detection)

Nous etudions la faisabilite de la detection du sillage de navires en imagerie radar, eventuellement bistatique, afin d’obtenir des parametres tels que le cap et la vitesse du navire. Dans un premier temps, on decrit la chaine d’acquisition radar bistatique ainsi que l’environnement maritime, en particulier les modeles de diffusion sur la surface rugueuse et la maniere d’obtenir une carte des hauteurs des vagues de sillage de Kelvin d’un navire. On decrit ensuite un simulateur de signaux radars bruts en configuration bistatique, en validant les resultats obtenus avec des donnees radar monostatiques disponibles dans la litterature. La seconde partie de la these est dediee a l’etude de la detectabilite du sillage de navires. On traite tout d’abord du cas de la detection du sillage d’eau morte, en realisant un test comparatif de quatre chaines de reference representatives. On traite ensuite la detectabilite du sillage de Kelvin dans des images radar de haute resolution, en commencant par discuter le choix d’une configuration radar optimisant la visibilite du sillage, puis en presentant un algorithme de detection et de traitement base sur la theorie du filtrage adapte stochastique. Cet algorithme fonctionne egalement sur des donnees d’imagerie spatiale optiques haute resolution.
Serologic evidence of Brucella infection in pinnipeds along the coast of Hokkaido, the northernmost main island of Japan

Brucella infection in Hokkaido was serologically surveyed in four species of pinnipeds inhabiting Cape Erimo during 2008–2013 and the Shiretoko Peninsula in 1999 by ELISA using Brucella abortus and B. canis as antigens. Anti‐Brucella positive sera showed higher absorbance to B. abortus than B. canis in almost all samples. Anti‐B. abortus antibodies were detected in serum samples from 24% (n = 55) of Western Pacific harbor seals (Phoca vitulina stejnegeri) in Cape Erimo and from 66% (n = 41) of spotted seals (P. largha), 15% (n = 20) of ribbon seals (Histriophoca fasciata) and 18% (n = 17) of Western Steller's sea lions (Eumetopias jubatus jubatus) in the Shiretoko Peninsula. Anti‐Brucella antibodies were detected at higher absorbance in 1‐ to 4‐year‐old harbor seals than in the pups and mature animals, suggesting either that Brucella infection mainly occurs after weaning or that it is maternally transmitted to pups with premature or suppressed immunity. Anti‐Brucella antibodies were detected in both immature and mature spotted seals and ribbon seals, with higher absorbance in the former. The antibodies were detected only in mature Western Steller's sea lions. Western blot analysis of the serum samples showed some differences in band appearances, namely discrete versus smeary, and in the number of bands, indicating that multiple different Brucella may be prevalent in pinnipeds in Hokkaido. Alternatively, the Brucella of pinnipeds may have some intra‐species diversity.
Learning event detection rules with noise hidden Markov models

Complex Event Processing (CEP) is a popular method to monitor processes in several contexts, especially when dealing with incidents at distinct points in time. Specific temporal combinations of various events are often of special interest for automatic detection. For the description of such patterns, one can either implement rules in some higher programming language or use some Event Description Language (EDL). Both is complicated and error-prone for non-engineers, because it varies greatly from natural language. Therefore, we present a method, by which a domain expert can simply signal the occurrence of a significant incident at a specific point in time. The system then infers rules for automatically detecting such occurrences later on. At the core of our approach is an extension of hidden Markov models (HMM) called noise hidden Markov models (nHMM) that can be trained with existing, low-level event data. The nHMM can be applied online without any intervention of programming experts. An evaluation on both synthetic and real event data shows the efficiency of our approach even under the presence of highly frequent, insignificant events and uncertainty in the data.
Robust architecture for locally-clocked extended burst-mode circuits without timing assumption

Asynchronous controllers based on Asynchronous Finite State Machines (AFSM) are widely used in the control unit design of asynchronous systems. These systems can be implemented in Field Programmable Gate Arrays (FPGAs), which are a low cost design alternative. Different styles have been proposed to implement AFSMs, but all of them have limitations when implemented in FPGAs. Therefore, this paper proposes a novel architecture for AFSMs in the local clock style. AFSMs are described in the extended burst-mode (XBM) specification. The existence of a local clock reduces the requirements of asynchronous logic, but the timing requirements may require the insertion of delays, which makes FPGA implementation difficult and leads to degradation of performance and reliability. The novel proposed local clock architecture is robust to setup and hold time violations, so they are free of timing analysis and do not need to introduce any kind of delays. The proposed architecture was applied to thirteen benchmarks and when compared to the local clock architecture of SICARELO tool, focused on FPGAs, it did not need to introduce any delays, whereas SICARELO had to introduce delays in all thirteen benchmarks of up to 4.9ns and there was an average reduction of 30% at the time of latency.
Misallocation or Mismeasurement?

The ratio of revenue to inputs differs greatly across plants within countries such as the U.S. and India. Such gaps may reflect misallocation which hinders aggregate productivity. But differences in measured average products need not reflect differences in true marginal products. We propose a way to estimate the gaps in true marginal products in the presence of measurement error. Our method exploits how revenue growth is less sensitive to input growth when a plant’s average products are overstated by measurement error. For Indian manufacturing from 1985–2013, our correction lowers potential gains from reallocation by 20%. For the U.S. the effect is even more dramatic, reducing potential gains by 60% and eliminating 2/3 of a severe downward trend in allocative efficiency over 1978–2013.
Hypoxic remodeling of the rat pulmonary arterial microcirculation assessed by microdissection.

Artery segments were microdissected from distal acini of the rat lung and studied by light and electron microscopy. Morphometric methods were used to quantify the structure of the wall at defined levels within the normal axial pathway and to determine the changes after 5 and 7 days of whole-animal exposure to hypobaric hypoxia at an inspiratory O2 fraction of 0.1. In the normal lung, at the level of the terminal bronchiolus, the artery wall comprised up to six layers of smooth muscle cells (SMCs). At the respiratory bronchiolar level, however, the wall contained fewer than two layers of SMCs with a consistently circumferential orientation. By the second-generation alveolar ducts (AD2), the medial layer was lost, replaced by subendothelial precursor smooth muscle cells (PCs) resembling intermediate cells. At this and the next level (AD3), the PC layer was often circumferentially discontinuous. Regression analysis of the morphometric data suggested, however, that the smallest AD3 artery is likely to have a layer of PCs but with virtually no measurable separation between them and the endothelium. The mean maximum radial diameter of SMCs decreased along the axial pathway with a significant difference between diameters at terminal bronchiolus and AD2 levels; yet the diameter of endothelial cells remained the same. After 7 days of hypoxia, no change was noted in the number of smooth muscle layers, but at the AD2 level the relative area of media in the total wall increased. This was due in part to hypertrophy of PCs, as evidenced by an increase in their mean maximum radial diameter. (ABSTRACT TRUNCATED AT 250 WORDS)
Political Marketing Power To Change The Choices Of The Electors: A Study On 1 November 2015 General Parliamentary Elections

The aim of this study is to evaluate the effects of political marketing done by political parties on the preferences and choices of the electors. In accordance with this aim, the concepts of political marketing, political marketing procedure and political marketing system are explained. Population of the research is consists of the electors from different cities and urban areas who voted in 1 November general parliamentary elections. The survey form is applied to 400 people which is above the limit value of n=384. The data collected through survey and questionnaire were evaluated using frequency-percentage analysis; “t-test” and “Variance (ANOVA) analysis” were used for unrelated measurements on the comparison of the opinions of the participants and demographic features of them. According to the results, the electors were affected more little by the near political marketing works to the date of the elections, while they were affected more by beforehand activities and marketing studies of the parties.
Architecture for Dynamic Information Dissemination and Fusion in Distributed Sensor Networks

In many embedded and distributed applications, very large number of sensors are deployed to gather important information for remote surveillance, continual monitoring and distributed target tracking. These sensors may be highly mobile and scattered over a wide area. Dissemination and fusion of real-time sensor information through these large self-organizing sensor networks must adapt rapidly to dynamic changes in sensor nodes configuration. In our system architecture, three main distributed services – lookup service, composition service, and dynamic adaptation service – provide support for dynamic information dissemination and fusion that adapt to incremental addition and removal of sensor nodes, device failure and degradation, migration of sensor nodes, and changing requirements in tasks and networks. These distributed services executing over a diffusion network layer to alleviate the problems of mobility, disconnection, dynamic reconfiguration, and limited power. When placed together impromptu, sensor nodes dynamically determine the capabilities of other sensor nodes and coordinate together to disseminate and fuse sensor information.
Diaphragm dysfunction in heart failure is accompanied by increases in neutral sphingomyelinase activity and ceramide content

Chronic heart failure (CHF) causes inspiratory (diaphragm) muscle weakness and fatigue that contributes to dyspnoea and limited physical capacity in patients. However, the mechanisms that lead to diaphragm dysfunction in CHF remain poorly understood. Cytokines and angiotensin II are elevated in CHF and stimulate the activity of the enzyme sphingomyelinase (SMase) and accumulation of its reaction product ceramide. In the diaphragm, SMase or ceramide exposure in vitro causes weakness and fatigue. Thus, elevated SMase activity and ceramide content have been proposed as mediators of diaphragm dysfunction in CHF. In the present study, we tested the hypotheses that diaphragm dysfunction was accompanied by increases in diaphragm SMase activity and ceramide content.
Altered distribution and synthesis of laminin‐5 (kalinin) in oral lichen planus, epithelial dysplasias and squamous cell carcinomas

Laminin‐5 is a glycoprotein which mediates epithelial cell adhesion to the basement membrane. This study describes the distribution and synthesis of laminin‐5 in oral lichen planus, epithelial dysplasias, squamous cell carcinomas and a lymph node metastasis using immunohistochemistry and in situ hybridization. In normal oral mucosa and lichen planus, immunoreaction to the laminin‐5 was seen as a thin continuous, delicate line in the basement membrane region, although slight irregularities in the thickness and intensity of the immunoreaction could be detected in some cases with lichen planus. In epithelial dysplasias, the laminin‐5 staining was discontinuous and more diffuse compared to lichen planus and normal mucosa. The immunoreaction was generally extracellular, although in some cases with lichen planus and epithelial dysplasia there were a few basal epithelial cells showing cytoplasmic staining. The invasive carcinomas and the lymph node metastasis showed a striking, intense cytoplasmic, staining of the carcinoma cells along the invasive border of the neoplastic islands and in individual infiltrating carcinoma cells. Using in situ hybridization, the laminin‐5 γ2 chain mRNA expression could not be detected in normal oral mucosa whereas, in non‐dysplastic lichen planus and, more strongly, in dysplasias, there was a clear increase in the expression of laminin‐5 mRNA in the basal epithelial cells. The most intensive signal was detected in the invasive front of the oral squamous cell carcinomas and the lymph node metastasis. We conclude that, in oral squamous cell carcinoma, there is altered synthesis and secretion of laminin‐5 mRNA and protein. It is also evident that in dysplastic lesions of oral epithelium the synthesis and distribution of laminin‐5 is abnormal.
The Economic Significance of Insurance Markets in Developing Countries

The importance of the relationship between financial development and economic growth is recognized in the economic literature. Recent evidence suggests that the developing countries have a supply-leading causality pattern of development. Property-Liability insurance like other financial services has grown in quantitative importance as part of the general development of financial institutions. This article investigates empirically the relationship between property-liability insurance premiums and economic and financial development. A model is specified for property-liability insurance demand and it is tested with a cross-section of 55 developing countries.
Yeast Mn2+ Transporter, Smf1p, Is Regulated by Ubiquitin-Dependent Vacuolar Protein Sorting

Conditional cdc1(Ts) mutants of S. cerevisiae arrest with a phenotype similar to that exhibited by Mn2+-depleted cells. Sequence similarity between Cdc1p and a class of Mn2+-dependent phosphoesterases, as well as the observation that conditional cdc1(Ts) growth can be ameliorated by Mn2+ supplement, suggests that Cdc1p activity is sensitive to intracellular Mn2+ levels. This article identifies several previously uncharacterized cdc1(Ts) suppressors as class E vps (vacuolar protein sorting) mutants and shows that these, as well as other vps mutants, accumulate high levels of intracellular Mn2+. Yeast VPS genes play a role in delivery of membrane transporters to the vacuole for degradation, and we show that the vps mutants accumulate elevated levels of the high-affinity Mn2+ transporter Smf1p. cdc1(Ts) conditional growth is also alleviated by mutations, including doa4 and ubc4, that compromise protein ubiquitination, and these ubiquitination defects are associated with Smf1p accumulation. Epistasis studies show that these suppressors require functional Smf1p to alleviate the cdc1(Ts) growth defect, whereas Smf1p is dispensable for cdc1(Ts) suppression by a mutation (cos16/per1) that does not influence intracellular Mn2+ levels. Because Smf1p is ubiquitinated in vivo, we propose that Smf1p is targeted to the vacuole for degradation by ubiquitination-dependent protein sorting.
Estimation of genetic parameters for milk and fat yields of dairy cattle in Spain and the United States.

Interaction of genotype with environment was studied with 10,780 Spanish production records (daughters of 210 Holstein-Friesian bulls) and two subsets of United States data (800,821 records with 1170 sires and 762,152 records with 1186 sires). Only 74 bulls had daughter records in both Spanish and United States data. Genetic and phenotypic (co)variances and correlations and heritability for milk and fat yields were estimated both within country and between countries with countries considered as separate traits (joint analysis). (Co)variance components were estimated with a REML procedure. Heritability estimates for milk and fat in the Spanish population (.16 and .14, within country; .12 and .09, joint) were smaller than for United States data (means of .33 and .31, within country; .26 and .24, joint). Genetic and phenotypic correlations between milk and fat within country were higher for Spain (.94 and .91) than for United States data (means of .66 and .81). Genetic correlation between countries averaged . 81 for milk and . 50 for fat. Rankings of bulls for milk yield are expected to be similar in Spain and the United States, although a scaling effect on predicted values is expected from different genetic variances in each country. Ranking of bulls for fat yield may be quite different.
Analysis of the Association between Chinese and International Commodity Futures Markets and Associated Co - integration Tests

In this article, author discusses the degree of association between China's commodity futures market and its international counterparts. Author establishes a co - integration relationship between the volume - series and open interest in food commodity futures market, using logarithm. The study suggests that there is a co - integration relation between the soybean futures price logarithm recorded in the Dalian market and the soybean spot price logarithm in the Heilongjiang market. This finding proves that China' s commodity futures markets have worked soundly. The study provides constructive ideas and poli cy proposals for the further development of China's commodity futures markets.
KURUM KÜLTÜRÜNÜN OLUŞUMUNDA KURUM İÇİ MOTİVASYONUN ROLÜ ÜZERİNE TEORİK BİR ÇALIŞMA

Corporate culture is the aggregate amount of common convictions and expectations which have been established in the employees’ minds by the rules that they have to comply with for their benefit. Those rules were aimed to put employees’ corporal actions in order for the future of the corporation. Corporate culture that is of a vital importance for embodying today and future of the corporate shows itself in the process of empleyees’ accepting and practising them. That the empleyees accept the rules and abide by them materializes through various factors. One of them is motivation that means helping employees focus on doing a certain work and reinforcing constantly. Corporate itself carries out a psychological impact on the employees thanks to various adequate motivation technics for the purpose of making up a corporate culture.
Correlation between Insulin Resistance and Thyroid Nodule in Type 2 Diabetes Mellitus

Objective The present study explored the association between insulin resistance (IR) and the clinical characteristics of thyroid nodules in patients with type 2 diabetes mellitus (T2DM). Methods All the patients were newly diagnosed with T2DM. 201 patients with thyroid nodule disease and 308 patients without the nodular thyroid disease. The participants were evaluated by relevant examination. Correlation analyses and regression analyses were performed to examine the relationships between the two groups. Results HOMA-IR values, serum FT4 (free thyroxine) levels, and age were higher in the thyroid nodule group than in the control group. The proportion of women in the thyroid nodule group is greater than the proportion of women in the control group. Logistic regression analysis showed that age, sex, FT4, and HOMA-IR were positive factors for thyroid nodule. The volume and size of the thyroid nodule were positively correlated with HOMA-IR, irrespective of gender. The thyroid nodule volume and size and the TSH (thyroid stimulating hormone) were greater in females than in males, whereas FT3 (free triiodothyronine) was lower in females. Conclusion IR might be a risk factor for thyroid nodule. Whether alleviating the IR might slow the growth, or diminish the volume and size of the thyroid nodules, is yet to be elucidated.