Miracle-dz/UniFAR-FTUs huggingface dataset:
An empirical study to address the problem of Unbalanced Data Sets in sentiment classification

With the emergence of Web 2.0, Sentiment Analysis is receiving more and more attention. Several interesting works were performed to address different issues in Sentiment Analysis. Nevertheless, the problem of Unbalanced Data Sets was not enough tackled within this research area. This paper presents the study we have carried out to address the problem of unbalanced data sets in supervised sentiment classification in a multi-lingual context. We propose three different methods to under-sample the majority class documents. These methods are Remove Similar, Remove Farthest and Remove by Clustering. Our goal is to compare the effectiveness of the proposed methods with the common random under-sampling. We also aim to evaluate the behavior of the classifiers toward different under-sampling rates. We use three different common classifiers, namely Naïve Bayes, Support Vector Machines and k-Nearest Neighbors. The experiments are carried out on two Arabic data sets and an English data set. We show that the four under-sampling methods are typically competitive. Naïve Bayes is shown as insensitive to unbalanced data sets. But Support Vector Machines seems to be highly sensitive to unbalanced data sets; k-Nearest Neighbors shows a slight sensitivity to imbalance in comparison with Support Vector Machines.
FULLY CONVEX NORMED LINEAR SPACES.

Foi any integer k > 2 and for i = 1, 2, 3, 4, let us consider the following conditions concerning X: (F.k.C.i) Every (k.i)-sequence {xnj in X is a Cauchy sequence. (W.F.k.C.i) Every (k.i)-sequence {xnj in X is weakly convergent. ' Condition (F.2.C.2) has been previously considered by V. Smulian.2 THEOREM 1. For any fixed integer k > 2 and for any normed linear space X, the four conditions (F.k.C.i), 1 < i < 4, are mutually equivalent. Also, the four conditions (W.F.k.C.i), 1 < i < 4, are mutually equivalent. Proof: To see that (F.k.C.1) =+ (F.k.C.2) and (W.F.k.C.1) =+(W.F.k.C.2), it suffices to show that for any (k.2)-sequence {[xn in a normed linear space, we can find a sequence { an) of real numbers with lim an = 1 such that { a1xn} is a -0 CO
Framework for IPTV QoS

The paper describes a framework for IPTV, with a practical implementation of the required QoS mechanisms. A cross-layer based solution enables QoS support for H.264 video streams at network layer. Selective dropping of packets based on their importance within the video stream is ensured by a new DiffServ per-hop behavior (PHB), suitable for real-time traffic (IPTV). The third element is a tool for measuring QoS parameters like: bandwidth, one-way delay, inter-packet jitter, packet loss, number of duplicated packets, out-of-order packets and corrupted packets. The implementation of this program opens the possibility of measuring the transmission parameters that influence QoS, with the purpose of offering a way to evaluate and control the services delivered by open-standards IPTV providers.
Cell Surface Display and Intracellular Trafficking of Free Glycosylphosphatidylinositols in Mammalian Cells*

In addition to serving as membrane anchors for cell surface proteins, glycosylphosphatidylinositols (GPIs) can be found abundantly as free glycolipids in mammalian cells. In this study we analyze the subcellular distribution and intracellular transport of metabolically radiolabeled GPIs in three different cell lines. We use a variety of membrane isolation techniques (subcellular fractionation, plasma membrane vesiculation to isolate pure plasma membrane fractions, and enveloped viruses to sample cellular membranes) to provide direct evidence that free GPIs are not confined to their site of synthesis, the endoplasmic reticulum, but can redistribute to populate other subcellular organelles. Over short labeling periods (2.5 h), radiolabeled GPIs were found at similar concentration in all subcellular fractions with the exception of a mitochondria-enriched fraction where GPI concentration was low. Pulse-chase experiments over extended chase periods showed that although the total amount of cellular radiolabeled GPIs decreased, the plasma membrane complement of labeled GPIs increased. GPIs at the plasma membrane were found to populate primarily the exoplasmic leaflet as detected using periodate oxidation of the cell surface. Transport of GPIs to the cell surface was inhibited by Brefeldin A and blocked at 15 °C, suggesting that GPIs are transported to the plasma membrane via a vesicular mechanism. The rate of transport of radiolabeled GPIs to the cell surface was found to be comparable with the rate of secretion of newly synthesized soluble proteins destined for the extracellular space.
Evidence that hepatic lipase deficiency in humans is not associated with proatherogenic changes in HDL composition and metabolism Published, JLR Papers in Press, June 1, 2004. DOI 10.1194/jlr.M400090-JLR200

The aim of the present study was to characterize the composition and metabolism of HDL in subjects with complete hepatic lipase (HL) deficiency. Analyses were carried out in three complete and three partial HL-deficient subjects as well as in eight normotriglyceridemic (NTG) and two hypertriglyceridemic controls. Complete HL deficiency was associated with hypertriglyceridemia and with a 3.5-fold increase in HDL-triglyceride (TG) levels. The in vivo kinetics of apolipoprotein A-I (apoA-I) and apoA-II (d < 1.25 g/l) were studied in the fasted state using a primed-constant infusion of l-(5,5,5-D3)leucine for 12 h. Complete HL deficiency was associated with a reduced fractional catabolic rate of apoA-I in the HL-deficient female proband (−47%) and in her two brothers (−21%) compared with gender- and TG-matched controls. Total plasma and HDL from complete HL-deficient patients were able to mediate normal cholesterol efflux from human skin fibroblasts labeled with [3H]cholesterol. Complete HL deficiency was also associated with normal levels of preβ-migrating apoA-I-containing HDL separated by two-dimensional gel electrophoresis and with an accumulation of large HDL particles compared with NTG controls. These results suggest that HL activity is important for adequate HDL metabolism, although its presence may not be necessary for normal HDL-mediated reverse cholesterol transport.
Route of Infection That Induces a High Intensity of Gamma Interferon-Secreting T Cells in the Genital Tract Produces Optimal Protection against Chlamydia trachomatis Infection in Mice

ABSTRACT The induction of local T helper type 1 (Th1)-mediated cellular immunity is crucial for resistance of mice to genital infection by the obligate intracellular bacterium Chlamydia trachomatis. We tested the hypothesis that the route of immunization that elicits relatively high numbers of chlamydia-specific, gamma interferon (IFN-γ)-secreting T lymphocytes (ISTLs) in the genital tract would induce optimal protective immunity against reinfection. Female BALB/c mice were infected intravaginally (i.v.), intranasally (i.n.), orally (p.o.), or subcutaneously (s.c.) with C. trachomatis. At days 7, 14, 21, and 28 postinfection, T cells isolated from the genital tract tissues were restimulated with chlamydial antigen in vitro, and the amounts of IFN-γ induced were measured by a sandwiched enzyme-linked immunosorbent assay method. At day 7 postinfection, i.n. - and i.v. -immunized mice had high levels of chlamydia-specific ISTLs in their genital tracts (203.58 ± 68.1 and 225.5 ± 12.1 pg/ml, respectively). However, there were no detectable ISTLs in the genital tracts of p.o. - or s.c. -infected mice. When preinfected mice were challenged i.v. 70 days later, animals preexposed by the i.n. route were highly resistant to reinfection, with greatly reduced chlamydial burden, and suffered an attenuated infection that resolved by day 6 postchallenge. Animals preexposed by the i.v. route were modestly protected, whereas p.o. and s.c. groups were indistinguishable in this regard from control mice. The resistance of i.n. -immunized mice (and to some extent the i.v.-exposed mice) to reinfection was associated with early appearance (within 24 h) of high levels of genital ISTLs compared with mice preinfected by other routes. Furthermore, although i.n. and i.v. -immunized mice had comparable levels of chlamydia-specific immunoglobulin A (IgA) antibodies in their vaginal washes, the levels of IgG2a were four- sixfold higher in i.n. -immunized mice than in any of the other groups. The results suggested that immunization routes that foster rapid induction of vigorous genital mucosal cell-mediated immune (CMI) effectors (e.g., IFN-γ), the CMI-associated humoral effector, IgG2a, and to some extent secretory IgA produce protective immunity against chlamydial genital infection. Therefore, i.n. immunization is a potential delivery route of choice in the development of a vaccine against Chlamydia.
Unexpected factors affecting the excitability of human motoneurones in voluntary and stimulated contractions

The output of human motoneurone pools decreases with fatiguing exercise, but the mechanisms involved are uncertain. We explored depression of recurrent motoneurone discharges (F‐waves) after sustained maximal voluntary contractions (MVCs). MVC depressed the size and frequency of F‐waves in a hand muscle but a submaximal contraction (at 50% MVC) did not. Surprisingly, activation of the motoneurones antidromically by stimulation of the ulnar nerve (at 20 or 40 Hz) did not depress F‐wave area or persistence. Furthermore, a sustained (3 min) MVC of a hand muscle depressed F‐waves in its antagonist but not in a remote hand muscle. Our findings suggest that depression of F‐waves after voluntary contractions is not simply due to repetitive activation of the motoneurones but requires descending voluntary drive. Furthermore, this effect may depress nearby, but not distant, spinal motoneurone pools.
The Phenylpropanoid Pathway and Lignin in Defense against Ganoderma boninense Colonized Root Tissues in Oil Palm (Elaeis guineensis Jacq.)

Basal stem rot, caused by the basidiomycete fungus, Ganoderma boninense, is an economically devastating disease in Malaysia. Our study investigated the changes in lignin content and composition along with activity and expression of the phenylpropanoid pathway enzymes and genes in oil palm root tissues during G. boninense infection. We sampled control (non-inoculated) and infected (inoculated) seedlings at seven time points [1, 2, 3, 4, 8, and 12 weeks post-inoculation (wpi)] in a randomized design. The expression profiles of phenylalanine ammonia lyase (PAL), cinnamyl alcohol dehydrogenase (CAD), and peroxidase (POD) genes were monitored at 1, 2, and 3 wpi using real-time quantitative polymerase chain reaction. Seedlings at 4, 8, and 12 wpi were screened for lignin content, lignin composition, enzyme activities (PAL, CAD, and POD), growth (weight and height), and disease severity (DS). Gene expression analysis demonstrated up-regulation of PAL, CAD, and POD genes in the infected seedlings, relative to the control seedlings at 1, 2, and 3 wpi. At 2 and 3 wpi, CAD showed highest transcript levels compared to PAL and POD. DS increased progressively throughout sampling, with 5, 34, and 69% at 4, 8, and 12 wpi, respectively. Fresh weight and height of the infected seedlings were significantly lower compared to the control seedlings at 8 and 12 wpi. Lignin content of the infected seedlings at 4 wpi was significantly higher than the control seedlings, remained elicited with no change at 8 wpi, and then collapsed with a significant reduction at 12 wpi. The nitrobenzene oxidation products of oil palm root lignin yielded both syringyl and guaiacyl monomers. Accumulation of lignin in the infected seedlings was in parallel to increased syringyl monomers, at 4 and 8 wpi. The activities of PAL and CAD enzymes in the infected seedlings at DS = 5–34% were significantly higher than the control seedlings and thereafter collapsed at DS = 69%.
Economic Insecurity and Political Stability: A Case for Growth-Targeting Systemic Vote

In this paper, we focus on the years before the Great Recession (1960–2007) and, after addressing possible issues of endogeneity, we study the effects of economic fluctuations on political stability. We find that when the economy is not in turmoil, there is a strong positive relationship between unemployment (i.e the major macroeconomic determinant of economic insecurity) and electoral support for systemic parties (i.e. parties with a serious aspiration to governing). That is, democratic politics respond to increasing economic insecurity by enhancing the prospects of political stability and, consequently, economic prosperity and growth.
Differential Item Functioning Analysis With Ordinal Logistic Regression Techniques: DIFdetect and difwithpar

Introduction:We present an ordinal logistic regression model for identification of items with differential item functioning (DIF) and apply this model to a Mini-Mental State Examination (MMSE) dataset. We employ item response theory ability estimation in our models. Three nested ordinal logistic regression models are applied to each item. Model testing begins with examination of the statistical significance of the interaction term between ability and the group indicator, consistent with nonuniform DIF. Then we turn our attention to the coefficient of the ability term in models with and without the group term. If including the group term has a marked effect on that coefficient, we declare that it has uniform DIF. We examined DIF related to language of test administration in addition to self-reported race, Hispanic ethnicity, age, years of education, and sex. Methods:We used PARSCALE for IRT analyses and STATA for ordinal logistic regression approaches. We used an iterative technique for adjusting IRT ability estimates on the basis of DIF findings. Results:Five items were found to have DIF related to language. These same items also had DIF related to other covariates. Discussion:The ordinal logistic regression approach to DIF detection, when combined with IRT ability estimates, provides a reasonable alternative for DIF detection. There appear to be several items with significant DIF related to language of test administration in the MMSE. More attention needs to be paid to the specific criteria used to determine whether an item has DIF, not just the technique used to identify DIF.
Development of 275 kV gas cooled type gas-insulated power transformer

The development of a 275 kV gas-cooled, gas-insulated power transformer with a sound level ideal for an urban area, which depends on SF/sub 6/ gas alone for both insulation and cooling, is described. The design philosophy, technical aspects, rating, and features of a 275 kV 30 MVA transformer are described, and the performance and long-term energization test results are discussed. >
Conformational heterogeneity of the M2 proton channel and a structural model for channel activation

The M2 protein of influenza virus A is a proton-selective ion channel activated by pH. Structure determination by solid-state and solution NMR and X-ray crystallography has contributed significantly to our understanding, but channel activation may involve conformations not captured by these studies. Indeed, solid-state NMR data demonstrate that the M2 protein possesses significant conformational heterogeneity. Here, we report molecular dynamics (MD) simulations of the M2 transmembrane domain (TMD) in the absence and presence of the antiviral drug amantadine. The ensembles of MD conformations for both apo and bound forms reproduced the NMR data well. The TMD helix was found to kink around Gly-34, where water molecules penetrated deeply into the backbone. The amantadine-bound form exhibited a single peak ≈10° in the distribution of helix-kink angle, but the apo form exhibited 2 peaks, ≈0° and 40°. Conformations of the apo form with small and large kink angles had narrow and wide pores, respectively, around the primary gate formed by His-37 and Trp-41. We propose a structural model for channel activation, in which the small-kink conformations dominate before proton uptake by His-37 from the exterior, and proton uptake makes the large-kink conformations more favorable, thereby priming His-37 for proton release to the interior.
Promote access speed of DRAM memory in net processor (NP) filed

Packet buffer allocate typically implemented using DRAM, which provides plentiful buffering at a reasonable cost. The problem we address is that a typical NP workload may be unable to utilize the peak DRAM bandwidth. Since the bandwidth of the packet buffer is often the bottleneck in the performance of a shared-memory packet switch. In this paper, we propose some ways to enhance average-case DRAM bandwidth. In modern DRAM, successive accesses falling within the same DRAM row are significantly faster than those falling across rows. If accesses to DRAM can be generated differently or reordered to take advantage of fast same-row accesses, peak DRAM bandwidth can be approached. This is the main point of this paper - row locality.
Offspring DNA methylation of the aryl-hydrocarbon receptor repressor gene is associated with maternal BMI, gestational age, and birth weight

Prenatal smoke exposure, maternal obesity, aberrant fetal growth, and preterm birth are all risk factors for offspring metabolic syndrome. Cord blood aryl-hydrocarbon receptor repressor (AHRR) DNA methylation is responsive to maternal smoking during pregnancy. AHRR serves not only to inhibit aryl-hydrocarbon receptor (AHR) transcription, which is involved in mediating xenobiotic metabolism, but it is also involved in cell growth and differentiation. Other than maternal smoking, other predictors of offspring AHRR DNA methylation status remain unknown; we sought to identify them among newborns. We enrolled pregnant women in the PROGRESS birth cohort in Mexico City. Using pyrosequencing, we analyzed DNA methylation of 3 CpG sites within the AHRR gene promoter from the umbilical cord blood of 531 infants. We used generalized estimating equations to account for the correlation of DNA methylation between CpG sites. Multivariable models were used to adjust for maternal age, BMI, education, parity, smoke-exposure, infant sex, gestational age, and birth weight-for-gestational age. AHRR DNA methylation was positively associated with maternal BMI (P = 0.0009) and negatively associated with the length of gestation (P < 0.0001) and birth weight-for-gestational age (P < 0.0001). AHRR DNA methylation was 2.1% higher in offspring of obese vs. normal weight mothers and 3.1% higher in preterm vs. term infants, representing a third and a half standard deviation differences in methylation, respectively. In conclusion, offspring AHRR DNA methylation was associated with maternal obesity during pregnancy as well as infant gestational age and birth weight-for-gestational age. Further work to discover the health impacts of altered AHRR DNA methylation is warranted.
Mobile Communication as a Social Stage

The spread of mobile communication among Finnish teenagers has been markedly rapid during the latter half of the 1990s. Young people have created and developed a communication culture that incorporates many special features, such as a rise in the use of text-based communication channels. Teenagers’ intersecting and selective use of communication channels has generated multimedial communication. From the theoretical standpoint provided by symbolic interactionism, we can ask whether communication through new media technologies generates new forms of social interaction. If this is the case, how could we describe and analyse these new forms of interaction? The media landscapes created by teenagers serve to articulate their personal space, as well as enabling their presentation of self and defining their relationships to others. This article is based on thematic interview material, and its purpose is to analyse the meanings and use contexts of mobile communication and other multimedial communication culture among Finnish youth.
Random-effects models for multivariate repeated measures

Mixed models are widely used for the analysis of one repeatedly measured outcome. If more than one outcome is present, a mixed model can be used for each one. These separate models can be tied together into a multivariate mixed model by specifying a joint distribution for their random effects. This strategy has been used for joining multivariate longitudinal profiles or other types of multivariate repeated data. However, computational problems are likely to occur when the number of outcomes increases. A pairwise modeling approach, in which all possible bivariate mixed models are fitted and where inference follows from pseudo-likelihood arguments, has been proposed to circumvent the dimensional limitations in multivariate mixed models. An analysis on 22-variate longitudinal measurements of hearing thresholds illustrates the performance of the pairwise approach in the context of multivariate linear mixed models. For generalized linear mixed models, a data set containing repeated measurements of seven aspects of psycho-cognitive functioning will be analyzed.
Photosynthetic epibionts and endobionts of Pacific oyster shells from oyster reefs in rocky versus mudflat shores

The Pacific oyster, Crassostrea gigas (Thunberg), is the main bivalve species cultivated in the world. With global warming enabling its reproduction and larval survival at higher latitudes, this species is now recognized as invasive and creates wild oyster reefs globally. In this study, the spatial distribution of photosynthetic assemblages colonizing the shells of wild C. gigas was investigated on both a large scale (two contrasting types of reefs found in mudflats and rocky areas) and a small scale (within individual shells) using a hyperspectral imager. The microspatial distribution of all phototrophs was obtained by mapping the Normalized Difference Vegetation Index (NDVI). Second derivative (δδ) analyses of hyperspectral images at 462, 524, 571 and 647 nm were subsequently applied to map diatoms, cyanobacteria, rhodophytes and chlorophytes, respectively. A concomitant pigment analysis was carried out by high performance liquid chromatography and completed by taxonomic observations. This study showed that there was high microalgal diversity associated with wild oyster shells and that there were differences in the structure of the phototropic assemblages depending on the type of reef. Namely, vertically-growing oysters in mudflat areas had a higher biomass of epizoic diatoms (hyperspectral proxy at δδ462 nm) and were mainly colonized by species of the genera Navicula, Nitzschia and Hippodonta, which are epipelic or motile epipsammic. The assemblages on the horizontal oysters contained more tychoplanktonic diatoms (e.g. Thalassiosira pseudonana, T. proschkinae and Plagiogrammopsis vanheurckii). Three species of boring cyanobacteria were observed for both types of reef: Mastigocoleus testarum, Leptolyngbya terrebrans, and Hyella caespistosa, but the second derivative analysis at 524 nm showed a significantly higher biomass for the horizontally-growing oysters. There was no biomass difference for the boring chlorophyte assemblages (δδ647 nm), with two species: Eugomontia testarum and Ostreobium quekettii observed for both types of reef. This study shows that oyster shells are an idiosyncratic but ubiquitous habitat for phototrophic assemblages. The contribution of these assemblages in terms of biomass and production to the functioning of coastal areas, and particularly to shellfish ecosystems, remains to be evaluated.