Miracle-dz/UniFAR-FTUs huggingface dataset:
European Conference on Information Systems ( ECIS ) 2008 Mapping Information Security Standards : A Counter-Terrorism Example

Although practitioners have mapped the alignment between IT-related standards, this work has rarely been reported in the academic literature. In particular the methods used have not been made explicit, which has limited the value of any reported results. The research described in this paper demonstrates a rigorous method for mapping the alignment between two example IT security standards. The two standards were Control Objectives for Information and Related Technology (COBIT), widely used as a comprehensive IT control framework, and the Australian Government Information and Communications Technology Security Manual (ACSI 33) which sets out policies and procedures for IT security for Australian government agencies. Conceptual analysis was used to analyse the alignment between the two standards to reveal some insightful patterns of use and emphasis. As one of the security standards defines the base level ICT security for Australian government agencies, related future work using conceptual analysis has the potential to contribute to improved evaluation of the preparedness of commercial Australian organisations to protect the security of their systems from terrorist activities. This paper illustrates the value of such work within a counter-terrorist setting, where leverage for systems security compliance can be gained from voluntary adoption of a commercial standard.
Generation of High‐Titer Defective HSV‐1 Vectors

Basic Protocol 1 describes the generation of helper virus stocks. Preparation of recombinant amplicon vector particles by transfection of amplicon and superinfection of helper virus into cells, and harvesting of packaged particles, is delineated in Basic Protocol 3. Thorough characterization of each amplicon viral vector stock involves measuring (1) the helper virus plaque‐forming units per ml (pfu/ml) on 2‐2 cells and (2) the amplicon stock infectious units per ml (iu/ml) on PC12 cells. The Support Protocols detail methods for determining titers of helper virus by plaque assay, and of amplicon stocks by vector assay. Curr. Protoc. Neurosci. 62:4.13. 1‐4.13. 15. © 2013 by John Wiley & Sons, Inc.
Left Ventricular Stress and Compliance in Man: With Special Reference to Normalized Ventricular Function Curves

Left ventricular circumferential end-diastolic stress (Sed), peak systolic stress (Sps), and compliance at end-diastole ([dV/VdP]ed) were estimated in 13 subjects with normal left ventricles (N group), nine subjects with inappropriate hypertrophy (IH group), five with aortic valvular stenosis (AS group), and six with congestive cardiomyopathy (CC group). The product of Sed and (dV/dP)ed was employed as an index of “muscle fiber stretch” and related to systolic indices of ventricular performance. Compliance was significantly less than normal in IH (P < 0.001), in AS (P < 0.01), and in CC (P < 0.001), while end-diastolic volumes were smaller than normal (P < 0.05), normal (P = NS), and larger than normal (P < 0.001) in the three groups, respectively. Sed was normal in IH and AS but elevated in CC (P < 0.001), while Sps was decreased in IH and normal in AS and CC. “Muscle fiber stretch,” however, was substantially less than normal in IH (P < 0.001), indicating that the low Sps is due at least in part to short sarcomeres. In CC, despite a markedly elevated preload, “muscle fiber stretch” was normal (P = NS), while work indices of the ventricle were diminished indicating depressed ventricular function. Thus, the product of Sed and (dV/VdP) ed provides a normalized index of “muscle fiber stretch,” which permits one to compare length-tension or length-work relationships in diseased ventricles of varying dimensions and compliance.
On the Accuracy of the Signal‐to‐Noise Estimates Obtained with the Exposure‐Time Calculator of the Wide Field Planetary Camera 2 on Board the Hubble Space Telescope

We have studied the accuracy and reliability of the exposure‐time calculator (ETC) of the Wide Field Planetary Camera 2 (WFPC2) on board the Hubble Space Telescope (HST) with the objective of determining how well it represents actual observations and therefore how much confidence can be invested in it and in similar software tools. We have found, for example, that the ETC gives, in certain circumstances, very optimistic values for the signal‐to‐noise ratio (S/N) of point sources. These values overestimate by up to a factor of 2 the HST performance when simulations are needed to plan deep‐imaging observations, thus bearing serious implications on observing‐time allocation. For this particular case, we calculate the corrective factors to compute the appropriate S/N and detection limits, and we show how these corrections vary with field crowding and sky background. We also compare the ETC of the WFPC2 with a more general ETC tool, which takes into account the real effects of pixel size and charge diffusion. Our analysis indicates that similar problems may afflict other ETCs in general, showing the limits to which they are bound and the caution with which their results must be taken.
Information fusion in a cloud computing era: A systems-level perspective

Information fusion utilizes a collection of data sources for uncertainty reduction, coverage extension, and situation awareness. Future information fusion solutions require systems design [1], coordination with users [2], metrics of performance [3], and methods of multilevel security [4]. A current trend that can enable all of these services is cloud computing. Cloud computing as defined by NIST is: Cloud computing is a model for enabling ubiquitous, convenient, on-demand network access to a shared pool of configurable computing resources (e.g., networks, servers, storage, applications, and services) that can be rapidly provisioned and released with minimal management effort or service provider interaction. [5] Cloud computing provides capabilities (on-demand self service, broad network access, resource pooling, rapid elasticity, and measured service) over different types of clouds (private, community, public, and hybrid).
Compressed data aggregation for energy efficient wireless sensor networks

As a burgeoning technique for signal processing, compressed sensing (CS) is being increasingly applied to wireless communications. However, little work is done to apply CS to multihop networking scenarios. In this paper, we investigate the application of CS to data collection in wireless sensor networks, and we aim at minimizing the network energy consumption through joint routing and compressed aggregation. We first characterize the optimal solution to this optimization problem, then we prove its NP-completeness. We further propose a mixed-integer programming formulation along with a greedy heuristic, from which both the optimal (for small scale problems) and the near-optimal (for large scale problems) aggregation trees are obtained. Our results validate the efficacy of the greedy heuristics, as well as the great improvement in energy efficiency through our joint routing and aggregation scheme.
Interpreting dual career couples' family life-cycles: Identifying strategic windows of global career opportunity

Dual career families are more resistant to undertaking expatriate assignments primarily due to the difficulties associated with the trailing spouse not being able to find a job overseas and the potential net financial loss for the couple. As reported in other research, the failure of spouse or family to adjust is the number one reason for expatriate failure, therefore, a model for selecting expatriate candidates that accommodates the dual career family should help international human resource managers. This paper examines some of the particular gender and sociological issues surrounding the dual career expatriate couple, such as family and career Life-Cycles, to identify ‘strategic windows’ of opportunities for relocating expatriates overseas. Several selection methods based on self selection, such as accomplishment review, plus corresponding appraisals by management are proposed as an alternative to the present dual career couple dilemma. The significance of this research lies in the necessity for organisations to be primarily aware of rapidly changing recruiting environments and to be willing to undertake the changes allowing for greater effectiveness of HRM process in global environments.
Epithelial-Mesenchymal Transition Induces Endoplasmic-Reticulum-Stress Response in Human Colorectal Tumor Cells

Tumor cells are stressed by unfavorable environmental conditions like hypoxia or starvation. Driven by the resulting cellular stress tumor cells undergo epithelial-mesenchymal transition. Additionally, cellular stress is accompanied by endoplasmic reticulum-stress which induces an unfolded protein response. It is unknown if epithelial-mesenchymal transition and endoplasmic reticulum-stress are occurring as independent parallel events or if an interrelationship exists between both of them. Here, we show that in colorectal cancer cells endoplasmic reticulum-stress depends on the induction of ZEB-1, which is a main factor of epithelial-mesenchymal transition. In the absence of ZEB-1 colorectal cancer cells cannot mount endoplasmic reticulum-stress as a reaction on cellular stress situations like hypoxia or starvation. Thus, our data suggest that there is a hierarchy in the development of cellular stress which starts with the presence of environmental stress that induces epithelial-mesenchymal transition which allows finally endoplasmic reticulum-stress. This finding highlights the central role of epithelial-mesenchymal transition during the process of tumorigenesis as epithelial-mesenchymal transition is also associated with chemoresistance and cancer stemness. Consequently, endoplasmic reticulum-stress might be a well suited target for chemotherapy of colorectal cancers.
Career Priority Patterns: Managerial and Professional Women in Bulgaria

This research examined correlates of three career priority patterns – career‐primary, modified career‐family, and career‐family – among 218 managerial and professional women in Bulgaria. Data were collected using questionnaires completed anonymously. It attempted to replicate similar research conducted in Canada. Although career‐family women worked fewer hours per week, and were less involved with their jobs than were career‐primary women, many of the differences observed in the Canadian sample were absent in the Bulgarian sample. Offers possible explanations for the differences in the two studies.
Perceived constraints to art museum attendance.

We explored selected socio-demographic factors that influence the perception of constraints to art museum attendance among a sample of interested individuals who were currently not enjoying art museum visitation. Data from the Survey of Public Participation in the Arts (SPPA), a nationwide survey were used for this study. Using multivariate analysis of variance, we examined five main effects (gender, age, income, number of children, and place of residence) and all two-way interactions on two dimensions of constraints, internal and external. Our findings illustrated that perceived constraints to art museum visitation were a function of not only separate but also interactive effects of the sociodemographic factors. Implications for both constraints theory and practice are discussed.
Haptic size aftereffects revisited

Although the existence of haptic size aftereffects has been known for quite some time, e.g. [1, 8, 10, 16], almost all of these studies investigated length and not volume as a measure of size. As the haptic aftereffect of three-dimensional volumes has so far only been observed qualitatively, we investigated the significance of this haptic size aftereffect in more detail by means of a size bisection task. The results are straightforward: after grasping a large sphere for a while, a subsequently grasped smaller test sphere feels even smaller. Likewise, adaptation to a small sphere results in perceiving larger spheres as even larger. The difference in perceived size in these two conditions is on average 24 %. An additional result is that in the haptic size bisection task with spheres as stimuli, participants use volume and not surface area or diameter as a measure of size, as might have been expected on the basis of a haptic volume discrimination task [5].
Systems engineering of RF system-on-wafer applications in SiGe [radar active electronic steered array example]

For moderate performance radar and communications systems operating at Ku-band and above, the use of entire wafers individually comprised of a lattice of low-power transmit-receive (T/R) modules is an economically attractive alternative to traditional approaches employing microwave tubes or MMICs that are individually packaged. Silicon germanium is presently the technology of choice because it offers the potential of reasonable power levels and performance in the f/sub T/, f/sub max/ regime above 200 GHz, together with yields unreachable using III-V compound semiconductors, the ability to integrate RF and logic, and prices approaching those of conventional CMOS. In this paper, we examine systems-level performance for such systems, focusing on an active electronic steered array (AESA) in a Ku-band coherent radar. The dependence of system performance on yield and circuit performance variation is explored.
Rounding pointers: type safe capabilities with C++ meta programming

Recent trends in secure operating systems indicate that an object-capability system is the security model with pre-eminent characteristics and practicality. Unlike traditional operating systems, which use a single global name space, object-capability systems name objects per protection domain. This allows a fine-grained isolation of the domains and follows the principle of least authority. Programming in such an environment differs considerably from traditional programming models. The fine-grained access to functionality requires a programming environment that supports the programmer when using a capability system. In this paper, we present an object-oriented framework that uses the C++ programming language to offer a frame-work for building and using operating-system components and applications.
Constraint driven Web service composition in METEOR-S

Creating Web processes using Web service technology gives us the opportunity for selecting new services, which best suit our need at the moment. Doing this automatically requires us to quantify our criteria for selection. In addition, there are challenging issues of correctness and optimality. We present a constraint driven Web service composition tool in METEOR-S, which allows the process designers to bind Web services to an abstract process, based on business and process constraints and generate an executable process. Our approach is to reduce much of the service composition problem to a constraint satisfaction problem. It uses a multiphase approach for constraint analysis. This work was done as part of the METEORS framework, which aims to support the complete lifecycle of semantic Web processes.
Substitution Mutations in the Myosin Essential Light Chain Lead to Reduced Actin-activated ATPase Activity Despite Stoichiometric Binding to the Heavy Chain*

Myosin essential light chain (ELC) wraps around an α-helix that extends from the myosin head, where it is believed to play a structural support role. To identify other role(s) of the ELC in myosin function, we have used an alanine scanning mutagenesis approach to convert charged residues in loops I, II, III, and helix G of the Dictyostelium ELC into uncharged alanines. Dictyostelium was used as a host system to study the phenotypic and biochemical consequences associated with the mutations. The ELC carrying loop mutations bound with normal stoichiometry to the myosin heavy chain when expressed in ELC-minus cells. When expressed in wild type cells these mutants competed efficiently with the endogenous ELC for binding, suggesting that the affinity of their interaction with the heavy chain is comparable to that of wild type. However, despite apparently normal association of ELC the cells still exhibited a reduced efficiency to undergo cytokinesis in suspension. Myosin purified from these cells exhibited 4-5-fold reduction in actin-activated ATPase activity and a decrease in motor function as assessed by an in vitro motility assay. These results suggest that the ELC contributes to myosin's enzymatic activity in addition to providing structural support for the α-helical neck region of myosin heavy chain.
An Agent-assisted Fuzzy cost based Multicast QoS routing in MANETs

Multicast routing and provision of QoS (Quality of Service) are challenging problems due to the dynamic topology and limited resources in Mobile Ad hoc Networks (MANETs). This paper proposes an agent based QoS routing algorithm that employs fuzzy logic to select an optimal path by considering multiple independent QoS metrics such as buffer occupancy rate, remaining battery capacity of a mobile node number of hops. In this method all the available resources of the path is converted into a single metric fuzzy cost. This is based on multi-criterion objective fuzzy measure. The path with the minimum fuzzy cost is used for the transmission. Here, the intelligent software agents move around the network and collect information of all mobile nodes. These agents can reduce the network delay and participate in network routing and route maintenance. The performance of the proposed Agent assisted Fuzzy cost based Multiobjective QoS Routing protocol (Agent_FCMQR) is compared with E-AOFR (Evolutionary Ad hoc On demand Fuzzy Routing) and MQRFT (Multi metric QoS routing based on Fuzzy Theory) and the simulation results show that the proposed protocol is superior over existing intelligence based routing protocols.
Highly Specific Role of Hypocretin (Orexin) Neurons: Differential Activation as a Function of Diurnal Phase, Operant Reinforcement versus Operant Avoidance and Light Level

Hypocretin (Hcrt) cell loss is responsible for narcolepsy, but Hcrt's role in normal behavior is unclear. We found that Hcrt knock-out mice were unable to work for food or water reward during the light phase. However, they were unimpaired relative to wild-type (WT) mice when working for reward during the dark phase or when working to avoid shock in the light or dark phase. In WT mice, expression of Fos in Hcrt neurons occurs only in the light phase when working for positive reinforcement. Expression was seen throughout the mediolateral extent of the Hcrt field. Fos was not expressed when expected or unexpected unearned rewards were presented, when working to avoid negative reinforcement, or when given or expecting shock, even though these conditions elicit maximal electroencephalogram (EEG) arousal. Fos was not expressed in the light phase when light was removed. This may explain the lack of light-induced arousal in narcoleptics and its presence in normal individuals. This is the first demonstration of such specificity of arousal system function and has implications for understanding the motivational and circadian consequences of arousal system dysfunction. The current results also indicate that comparable and complementary specificities must exist in other arousal systems.
Spaces of Capital: Towards a Critical Geography

David Harvey is unquestionably the most influential, as well as the most cited, geographer of his generation. His reputation extends well beyond geography to sociology, planning, architecture, anthropology, literary studies and political science. This book brings together for the first time seminal articles published over three decades on the tensions between geographical knowledges and political power and on the capitalist production of space. Classic essays reprinted here include 'On the history and present condition of geography', 'The geography of capitalist accumulation' and 'The spatial fix: Hegel, von Thunen, and Marx'. Two new chapters represent the author's most recent thinking on cartographic identities and social movements. David Harvey's persistent challenge to the claims of ethical neutrality on behalf of science and geography runs like a thread throughout the book. He seeks to explain the geopolitics of capitalism and to ground spatial theory in social justice. In the process he engages with overlooked or misrepresented figures in the history of geography, placing them in the context of intellectual history. The presence here of Kant, Von Thunen, Humboldt, Lattimore, Leopold alongside Marx, Hegel, Heidegger, Darwin, Malthus, Foucault and many others shows the deep roots and significance of geographical thought. At the same time David Harvey's telling observations of current social, environmental, and political trends show just how vital that thought is to the understanding of the world as it is and as it might be.
Site-directed mutagenesis of the proposed catalytic amino acids of the Sindbis virus capsid protein autoprotease

The structural proteins of Sindbis virus are translated as a polyprotein precursor that is cleaved upon translation. The capsid protein is postulated to be a serine protease that releases itself from the N terminus of the nascent polyprotein by autoproteolysis. We have tested the importance in autoproteolysis of His-141, Asp-147, and Ser-215, previously postulated to form the catalytic triad of the protease, and of Asp-163. Several site-specific mutations were constructed at each of these positions, and the release of the capsid protein during translation in a cell-free system was examined. Because proteolysis occurs in cis during translation, the kinetics of release cannot be determined in this system, but the extent of proteolysis can be ascertained. Ser-215 appears to be the catalytic serine of the proteinase. Cys or Thr could substitute inefficiently for Ser-215, but substitution with Ala or Ile led to complete loss of activity. His-141 was also important for proteolysis. Substitution with Ala or Pro led to total loss of activity. Surprisingly, substitution with Arg resulted in complete proteolysis in vitro. Changes at the two Asp residues resulted in complete proteolysis of the substrate in vitro. All mutations that resulted in at least partial cleavage in vitro were incorporated into a full-length clone of Sindbis virus and an attempt was made to recover mutant virus. All changes tested were lethal for the virus except Asp-163 to Asn. Thus, production of infectious virus is either a more sensitive measure of the catalytic rate than the extent of in vitro cleavage, or these residues have necessary functions in addition to their possible role in proteolysis.