Miracle-dz/UniFAR-FTUs huggingface dataset:
Efficacy of Biodanza for treating women with fibromyalgia.

OBJECTIVE The objective of this study was to determine the effects of a 3-month Biodanza intervention in women with fibromyalgia (FM). DESIGN This was a controlled trial. SETTING/LOCATION The study was conducted at a university research laboratory and social center. SUBJECTS The study comprised 59 women with FM recruited from a local association of patients with FM. Participants were allocated to the Biodanza intervention group (n = 27) or usual-care group (n = 32). INTERVENTION The Biodanza intervention was carried out once a week for 3 months. OUTCOME MEASURES The outcome measures included the following: Pain threshold, body composition (body-mass index and estimated body fat percentage), physical fitness (30-second chair stand, handgrip strength, chair sit and reach, back scratch, blind flamingo, 8 feet up and go, and 6-minute walk test) and psychologic outcomes (Fibromyalgia Impact Questionnaire [FIQ], Short-Form Health Survey 36, Vanderbilt Pain Management Inventory, Hospital Anxiety and Depression Scale, General Self-Efficacy Scale, and Rosenberg Self-Esteem Scale). RESULTS We observed a significant interaction effect (group*time) for pain threshold of several tender points (left [L] and right [R] side of the anterior cervical and supraspinatus, trapezius L and lateral epicondyle R, algometer score, tender points count), body fat percentage, and FIQ total score. In the intervention group, post hoc analysis revealed a significant improvement in pain threshold of the anterior cervical R and L and supraspinatus R and L tender points (all p < 0.05), algometer score (p = 0.008), tender point count (p = 0.002), body fat percentage (p = 0.001), and FIQ total score (p = 0.003). CONCLUSIONS A 3-month (one session per week) Biodanza intervention shows improvements on pain, body composition, and FM impact in female patients.
First demonstration of a full 28nm high-k/metal gate circuit transfer from Bulk to UTBB FDSOI technology through hybrid integration

For the first time a full hybrid integration scheme is proposed, allowing a full circuit design transfer from 28nm Bulk CMOS high-k/metal gate onto UTBB FDSOI with minimum design effort. As the performance of FDSOI logic and SRAM devices have already been reported, this paper highlights the original way to integrate ESD devices, variable MOS capacitors and vertical bipolar transistor within the frame of our hybrid technology. Competitive ESD performance for the same footprint is achieved through hybrid MOSFETS snap-back voltage reduction, obtained by implant engineering. In addition, we demonstrate that the performance of Silicon Controlled Rectifier (SCR) and ESD diodes are matched vs Bulk technology while maintaining the performance of FDSOI devices and without any additional masks.
Energy Consumption Comparison of Interactive Cloud-Based and Local Applications

Interactive cloud computing and cloud-based applications are a rapidly growing sector of the expanding digital economy because they provide access to advanced computing and storage services via simple, compact personal devices. Recent studies have suggested that processing a task in the cloud is more energy-efficient than processing the same task locally. However, these studies have generally ignored the power consumption of the network and end-user devices when accessing the cloud. In this paper, we develop a power consumption model for interactive cloud applications that includes the power consumption of end-user devices and the influence of the applications on the power consumption of the various network elements along the path between the user and the cloud data centre. As examples, we apply our model to Google Drive and Microsoft Skydrive's word processing, presentation and spreadsheet interactive applications. We demonstrate via extensive packet-level traffic measurements that the volume of traffic generated by a session of the application vastly exceeds the amount of data keyed in by the user. This has important implications on the overall power consumption of the service. We show that using the cloud to perform certain tasks consumes more power (by a watt to 10 watts depending on the scenario) than performing the same tasks locally on a low-power consuming computer and a tablet.
Real-Time 3D Road Scene Based on Virtual-Real Fusion Method

Road monitoring plays a vital role in emergency disposal, traffic accident liability determination, traffic trend analyzes, and other fields. This paper designs a real-time virtual-real fusion framework for multiview surveillance of large-scale scene, in which 2D panorama, satellite texture, and 3D model are merged. The system is implemented with the following contributions. First, a novel automatic mosaic algorithm for multiview overlapped images is proposed. Feature points between adjacent cameras are detected via comotion statistics map. In addition, transformation model is obtained using random sample consensus algorithm. Second, multiview images are morphed to a same overhead viewpoint. Finally, 2D panoramic road image and 3D scene model are combined based on high-precision ground control points. The proposed framework has been successfully applied to a large road intersection. With the virtual-real fusion approach, observers can freely monitor and ramble in the large-scale 3-D road scene.
Usage of data mining techniques for analyzing network intrusions

This paper presents the results of the analysis of the network intrusion detection systems using data mining techniques and anomaly detection. Anomaly detection technique is present for a while in the area of data mining. Previous papers that implement data mining techniques to detect anomaly attacks actually use well-known techniques such as classification or clustering. Anomaly detection technique combines all these techniques. They are also facing problem on the fact that many of the attacks do not have some kind of signature on network and transport layer, so it is not easy to train models for these type of attacks. Network dataset that was used in this paper is DARPA 1998 dataset created in MIT Lincoln Laboratory and is used worldwide for the network testing purposes.
Étude d'un système portable d'inspection par rayonnement X utilisant les effets combinés d'absorption multi-énergies, de diffusion et diffraction X sur la matière

Les travaux proposes portent sur la caracterisation par rayons X des materiaux, en vue d'une discrimination des explosifs par rapport aux materiaux communs. Trois methodes d'analyses utilisant les rayons X sont decrites : la methode de transmission multi-energies, la diffusion Compton et la diffraction. Ces trois methodes sont abordees sous un angle theorique puis experimental. Le memoire se compose de quatre parties. Apres une presentation du contexte general de l'etude, les phenomenes physiques mis en jeu et les proprietes des materiaux concernes sont donnes. Dans une seconde partie consacree a la transmission, le principe d'imagerie 2D multi-energie est presente. Puis, nous developpons une approche d'imagerie 3D bi-energie, qui permet une representation des materiaux dans une base de densite et numero atomique effectifs. Cette approche rend possible la discrimination d'un certain nombre de materiaux explosifs. Dans la troisieme partie, la diffraction des rayons X est abordee, en vue d'identifier les materiaux par leur signature spectrale. Les cristallins et semi-cristallins sont reconnus, mais pas les amorphes. La quatrieme partie s'interesse a la diffusion Compton. Nous avons teste differentes methodes d'acquisition : pinhole, masques codes et une methode par balayage avec un faisceau de rayons X filiforme. Ces techniques permettent d'obtenir des images d'objets. Le dispositif etant d'un meme cote de l'objet, il est particulierement interessant dans certaines situations de terrain. En synthese, nous discutons de la complementarite des informations issues de ces differentes techniques en vue de specifier les caracteristiques d'un systeme portable permettant des analyses de terrain
FURTHER EVIDENCE OF THE EXISTENCE OF MITOCHONDRIA IN BACTERIA

The granules of mycobacteria, originally described by Robert Koch as spores, have been shown in a preceding communication to be sites of oxidative-reductive enzymatic activity. In respect to several enzymatic reactions, as well as in tinctorial and morphological characteristics, these mycobacterial granules were shown to correspond to mitochondria (Mudd, Winterscheid, DeLamater, and Henderson, 1951). In the present communication granules in several other species of bacteria have been examined by similar criteria. These granules also have been found to correspond in essential characteristics to mitochondria.
Application of clustering techniques to mixture density modelling for continuous-speech recognition

Clustering techniques have been integrated at different levels into the training procedure of a continuous-density hidden Markov model (HMM) speech recognizer. These clustering techniques can be used in two ways. First acoustically similar states are tied together. It will help to reduce the number of parameters but also allow to train otherwise rarely seen states together with more robust ones (state-tying). Secondly densities are clustered across states, this reduces the number of densities while at the same time keeping the best performances of our recognizer (density-clustering). We have applied these techniques both to word-based small-vocabulary and phoneme-based large-vocabulary recognition tasks. On the WSJ task, we could achieve a reduction of the word error rate by 7%. On the TI/NIST-connected digit task, the number of parameters was reduced by a factor 2-3 while keeping the same string error rate.
Does felt age reflect health‐related quality of life in cancer patients?

Subjective age is related to health and to life satisfaction. The present study on post‐surgical cancer patients addressed two questions: (1) Do people differ in their health‐related quality of life (HRQOL) depending on their felt age? (2) Is change in felt age associated with change in HRQOL? Data were collected at one month (T1) and six months (T2) after surgery (N=159; 58% men, aged 24–86 years). At both waves, less than 14% of the patients felt older than their chronological age. Patients who felt younger than their age and patients who felt as old as they were reported better HRQOL than those subjectively feeling older. Between T1 and T2, an increment of felt age was found in 29% and a decrement in 28% of cases. HRQOL improved also among those who subjectively aged and among those whose felt age did not change, but in fewer aspects and with substantially lower effect sizes than among those whose felt age decreased. HRQOL is a correlate of felt age. However, an increment in felt age does not imply a decrease of HRQOL. Copyright © 2005 John Wiley & Sons, Ltd.
The Acidic Domain and First Immunoglobulin-Like Loop of Fibroblast Growth Factor Receptor 2 Modulate Downstream Signaling through Glycosaminoglycan Modification

ABSTRACT Fibroblast growth factor receptors (FGFRs) are membrane-spanning tyrosine kinases that have been implicated in a variety of biological processes including mitogenesis, cell migration, development, and differentiation. We identified a unique isoform of FGFR2 expressed as a diffuse band with an unusually large molecular mass. This receptor is modified by glycosaminoglycan at a Ser residue located immediately N terminal to the acidic box, a stretch of acidic amino acids. The acidic box and the glycosaminoglycan modification site are encoded by an alternative exon of the FGFR2 gene. The acidic box appears to play an important role in glycosaminoglycan modification, and the presence of this domain is required for modification by heparan sulfate glycosaminoglycan. Moreover, the presence of the first immunoglobulin-like domain encoded by another alternative exon abrogated the modification. The high-affinity receptor with heparan sulfate modification enhanced receptor autophosphorylation, substrate phosphorylation, and ternary complex factor-independent gene expression. It also sustained mitogen-activated protein kinase activity and increased eventual DNA synthesis, a long-term response to fibroblast growth factor stimulation, at physiological ligand concentrations. We propose a novel regulation mechanism of FGFR2 signal transduction through glycosaminoglycan modification.
Cardiometabolic correlates and heritability of fetuin-A, retinol-binding protein 4, and fatty-acid binding protein 4 in the Framingham Heart Study.

CONTEXT Fetuin-A, retinol-binding protein 4 (RBP4), and fatty-acid binding protein 4 (FABP4) are novel biomarkers that may link adiposity to insulin resistance and the metabolic syndrome (MetSyn). OBJECTIVE The aim of this study was to investigate the correlates of these three adiposity biomarkers in a large community-based sample. DESIGN, SETTING, PARTICIPANTS, AND OUTCOMES: Serum concentrations of fetuin-A, RBP4, and FABP4 were assayed in 3658 participants of the Third Generation Framingham Heart Study cohort (mean age 40 yr, 54% women). We used multivariable regression to cross-sectionally relate biomarkers to insulin resistance, cardiovascular risk factors, and the MetSyn. The genetic contribution to inter-individual variation in biomarker levels was assessed using variance-components analysis. RESULTS All three biomarkers exhibited sexual dimorphisms (levels higher in women for fetuin-A and FABP4 but greater in men for RBP4) and were associated positively with insulin resistance assessed using the homeostasis model, with high-sensitivity C-reactive protein, and with prevalent MetSyn (P<0.01 for all). The biomarkers showed distinct patterns of association with metabolic risk factors. RBP4 levels were correlated with body mass index only in unadjusted but not in adjusted models. None of the biomarkers were associated with prevalent diabetes in multivariable models. Circulating fetuin-A, RBP4, and FABP4 levels showed modest heritability, ranging from 15-44% (all P<0.0001). CONCLUSIONS In our large young- to middle-aged community-based sample, we observed that circulating levels of fetuin-A, RBP4, and FABP4 are associated with insulin resistance and with distinct components of MetSyn consistent with the multifactorial pathogenesis of metabolic dysregulation.
Movement similarity assessment using symbolic representation of trajectories

This article describes a novel approach for finding similar trajectories, using trajectory segmentation based on movement parameters (MPs) such as speed, acceleration, or direction. First, a segmentation technique is applied to decompose trajectories into a set of segments with homogeneous characteristics with respect to a particular MP. Each segment is assigned to a movement parameter class (MPC), representing the behavior of the MP. Accordingly, the segmentation procedure transforms a trajectory to a sequence of class labels, that is, a symbolic representation. A modified version of edit distance called normalized weighted edit distance (NWED) is introduced as a similarity measure between different sequences. As an application, we demonstrate how the method can be employed to cluster trajectories. The performance of the approach is assessed in two case studies using real movement datasets from two different application domains, namely, North Atlantic Hurricane trajectories and GPS tracks of couriers in London. Three different experiments have been conducted that respond to different facets of the proposed techniques and that compare our NWED measure to a related method.
Translation and validation of the Revised-Algase Wandering Scale (community version) among Korean elders with dementia

The purpose of this study was to examine the psychometric properties of a Korean translated version of the Revised Algase Wandering Scale, community version (K-RAWS-CV) among persons with dementia in Korea. A cross-sectional survey design was used. After established equivalence of the instrument using back-translation and a field test, 69 community dwelling family caregivers described the wandering behavior of their family members with dementia. The overall mean of the K-RAWS-CV was 1.73 (SD = 0.61, range = 1–3.87). Means of each subscale ranged from 1.44 (meal-time impulsivity, MI) to 2.04 (escape behavior, EB). The reliability alpha for the overall scale was 0.96 with reliabilities for subscales ranging from 0.82 (negative outcome, NO) to 0.93 (persistent walking, PW). The correlation between the overall K-RAWS-CV and each subscale ranged from 0.52 (overall and NO) to 0.82 (overall and PW) with a mean value of 0.66. Pearson's correlations between the level of cognitive impairment and each subscale of the K-RAWS-CV demonstrated significant, moderate relationships ranging from −0.24 (MI, RW, and MMSE) to −0.39 (PW, EB and MMSE). Mean differences between wanderers and non-wanderers were statistically significant for the K-RAWS-CV overall and all subscale except for MI. Results support the validity and reliability of the K-RAWS-CV overall and the six subscales.
A scalable instruction buffer and align unit for xDSPcore

Increasing mask costs and decreasing feature sizes together with productivity demand have led to the trend of platform design. Software programmable embedded cores are used to provide the necessary flexibility in integrated systems. Facing increasing system complexity, single-issue digital signal processors (DSPs) have been replaced by cores providing the execution of several instructions in parallel. The most common programming model for multi-issue DSP core architectures is Very Long Instruction Word (VLIW) which is based on static scheduling, and enables minimization of the worst case execution time and reduces core complexity. The drawback of traditional VLIW is poor code density, which leads to high program memory requirements and, therefore, requires a large silicon area of the DSP subsystem. To overcome this problem without limiting the core performance, a scalable long instruction word (xLIW) is introduced. A special align unit is used for implementing the xLIW program memory interface. In this paper, the align unit and its main architectural feature, a scalable instruction buffer, is introduced in detail. xLIW is part of a project for a parameterized DSP core.
Variation in NF-κB Signaling Pathways and Survival in Invasive Epithelial Ovarian Cancer

Survival in epithelial ovarian cancer (EOC) is influenced by the host immune response, yet the key genetic determinants of inflammation and immunity that affect prognosis are not known. The nuclear factor-κB (NF-κB) transcription factor family plays an important role in many immune and inflammatory responses, including the response to cancer. We studied common inherited variation in 210 genes in the NF-κB family in 10,084 patients with invasive EOC (5,248 high-grade serous, 1,452 endometrioid, 795 clear cell, and 661 mucinous) from the Ovarian Cancer Association Consortium. Associations between genotype and overall survival were assessed using Cox regression for all patients and by major histology, adjusting for known prognostic factors and correcting for multiple testing (threshold for statistical significance, P < 2.5 × 10−5). Results were statistically significant when assessed for patients of a single histology. Key associations were with caspase recruitment domain family, member 11 (CARD11) rs41324349 in patients with mucinous EOC [HR, 1.82; 95% confidence interval (CI), 1.41–2.35; P = 4.13 × 10−6] and tumor necrosis factor receptor superfamily, member 13B (TNFRSF13B) rs7501462 in patients with endometrioid EOC (HR, 0.68; 95% CI, 0.56–0.82; P = 2.33 × 10−5). Other associations of note included TNF receptor–associated factor 2 (TRAF2) rs17250239 in patients with high-grade serous EOC (HR, 0.84; 95% CI, 0.77–0.92; P = 6.49 × 10−5) and phospholipase C, gamma 1 (PLCG1) rs11696662 in patients with clear cell EOC (HR, 0.43; 95% CI, 0.26–0.73; P = 4.56 × 10−4). These associations highlight the potential importance of genes associated with host inflammation and immunity in modulating clinical outcomes in distinct EOC histologies. Cancer Epidemiol Biomarkers Prev; 23(7); 1421–7. ©2014 AACR.
Error probability of physical-layer network coding in multiple-antenna two-way relay channel

In this paper, we investigate the error probability and the diversity order of physical-layer network coding (PNC) in the two-way relay channel (TWRC), where two users communicate with the help of a relay. Each user has one antenna and the relay has two antennas. The system operates in a half-duplex mode with binary phase shift keying (BPSK) modulation. All the channels are Rayleigh faded. In particular, we consider a general asymmetric case, where two users have different average signal-to-noise ratio (SNR) to the relay. The upper and lower bounds on the instantaneous and average error probability of the uplink channel are derived based on the maximum-likelihood (ML) criterion. We also investigate the diversity order of the uplink channel. Numerical result demonstrates that the bounds are much tighter than other existing work, especially at low SNR, and the analytical result shows that the diversity is two for the asymmetric uplink channel.
A new workforce in the making? A case study of strategic human resource management in a whole-system change effort in healthcare.

PURPOSE This paper seeks to describe the exploration of human resource issues in one large-scale program of innovation in healthcare. It is informed by established theories of management in the workplace and a multi-level model of diffusion of innovations. DESIGN/METHODOLOGY/APPROACH A realist approach was used based on interviews, ethnographic observation and documentary analysis. FINDINGS Five main approaches ("theories of change") were adopted to develop and support the workforce: recruiting staff with skills in service transformation; redesigning roles and creating new roles; enhancing workforce planning; linking staff development to service needs; creating opportunities for shared learning and knowledge exchange. Each had differing levels of success. PRACTICAL IMPLICATIONS The paper includes HR implications for the modernisation of a complex service organisation. ORIGINALITY/VALUE This is the first time a realist evaluation of a complex health modernisation initiative has been undertaken.