Miracle-dz/UniFAR-FTUs huggingface dataset:
Green engineering principles promote low-impact development.

This article considers the use of low-impact development (LID) which integrates environmental concerns with land development, focusing on water and pollutant balances. Urbanisation makes drastic changes to the hydrological characteristics of land: materials used contribute higher pollutant loads and natural filtering is reduced. Pollutant sources in runoff water include fertilisers, animal wastes, cars, fuels, herbicides and pesticides. LID design attempts to replicate pre-development hydrologic conditions as closely as possible. Elements are present in site design and preparation, and in runoff management practices such as bioretention areas to collect and treat runoff water. Obstacles to using LID include access requirements for certain sizes of vehicle, safety concerns and public health issues, beside economic concerns. Using LID solves some environmental issues but raises others such as the ownership (for treatment purposes) of captured pollutants. Incorporating LID should not encourage urban sprawl.
The outcome and a new ISN/RPS 2003 classification of lupus nephritis in Japanese.

BACKGROUND A considerable diversity in prognosis is seen with lupus glomerulonephritis (LGN). Hence, the clinical usefulness of a recent International Society of Nephrology/Renal Pathology Society (ISN/RPS) 2003 classification to judge the long-term outcome of human LGN has been investigated. METHODS We studied retrospectively 60 subjects with LGN (7 males, 53 females, mean age of 33 years old) who underwent renal biopsies and were followed from 1 to 366 months, with a mean of 187 months. We diagnosed renal pathology as classes, active and sclerosing lesions, according to the new and WHO1995 classification of LGN, and analyzed the clinicopathologic factors affecting to the prognosis of LGN. RESULTS New classification got much higher consensus in the judgment of classes (98% vs. 83%, P = 0.0084). The group of Class IV-S (N = 6) or IV-G (N = 17) at initial biopsies showed higher rate of end-stage renal failure (ESRF) compared with that of Class I, II, III or V (40.9% vs. 2.6%, P < 0.001). The mean 50% renal survival time of Class IV was 189 +/- 29 months, and patients with Class IV-S tended to have a poorer prognosis (95 +/- 22 months for IV-S vs. 214 +/- 35 months for IV-G, P = 0.1495). Class IV was also selected as the most significant risk factor for ESRF by stepwise model (P = 0.002). In subanalysis for ESRF in Class IV (-S or -G), treatment including methylprednisolone pulse therapy was only selected as a significant improving factor for primary outcome (P = 0.034). In addition, activity index was the significant risk factor of death and/or ESRF after initial renal biopsies (P = 0.043). As for actuarial patient death during all follow-up periods, complications with anti-phospholipid syndrome or nephrotic syndrome were significant risk factors (P = 0.013, P = 0.041, respectively). CONCLUSION New ISN/RPS 2003 classification provided beneficial pathologic information relevant to the long-term renal outcome and the optimal therapy preventing ESRF and/or death in patients with LGN.
The impact of stock market and macroeconomic variables on real estate prices dynamics: evidence from Saudi Arabia

To enhance portfolio return and achieve diversification, Saudi investors have long been seeking opportunities in real estate markets since the crash of Saudi stock market on February 2006. The aim of this paper is to explain the determinants of real estate price dynamics in the case of Saudi Arabia. Using monthly data from January 2008 to December 2012, we examine the impact of key monetary policy and macroeconomic variables, including money supply growth, inflation rates and interest rate, on the real estate price growth dynamics in Saudi Arabia. We study also the effect of stock market conditions (return and conditional volatility) on explaining real estate price movement. This study has important implications for investment decision and real estate market analysis in the case of an important real estate market.
Clinical experience with two‐dimensional echocardiography to guide endomyocardial biopsy

Two‐dimensional echocardiography was used to aid right ventricular endomyocardial biopsy during 163 procedures in 83 patients being evaluated for myocarditis, cardiac transplant rejection, or drug toxicity. Thirty procedures were performed using combined echocardiography and fluoroscopy and 133 using echocardiography alone. For 80 of the 83 patients (96%) the forceps could be adequately visualized entering the right atrium, crossing the tricuspid valve, and advancing to the right ventricular apex and free wall. The catheter could be guided to biopsy the septum and sample multiple, separate sites along the right ventricular walls. By opening the forceps prior to contact with the myocardium, the right ventricular free wall could be biopsied without perforation. We found two‐dimensional echocardiography to be a useful and safe technique for forceps visualization and manipulation in the right ventricle.
Selenium binding and distribution in goat and cow milk..

Raw milk from goats and cows (bovine) was combined with sodium selenite (.5 muCi/10 ml milk) and incubated at 39 C to allow selenium binding to milk components. After incubation intervals between . 5 and 24 h, samples were separated into cream, whey, and casein fractions by centrifugation and acid precipitation. When samples were incubated up to 6 h, the aqueous whey fraction contained the highest amounts of radioactivity, the casein substantially less, and the cream contained little senenium-75. Twenty-four hours of incubation at 39 C caused the samples to curdle, resulting in a major shift of radioactivity from the aqueous phase to the acid precipitable (casein) fraction. This shift occurred in all curdled samples irrespective of time or temperature of incubation. Acidifying milk samples with lactic acid in the presence of a bacterial inhibitor also increased selenium binding by the casein fraction. Samples of whey fractions were applied to a Sephadex gel filtration column for further separation. Most of the selenium-75 was recovered in low molecular weight fractions. Radioaactive selenium appeared to remain largely in the unbound ionic form when added to noncurdled goats' or cows' milk. Most of the selenite added to milk does not combine with proteins at normal pH but increasingly does so as pH falls below 6.0.
Reg IV is an independent prognostic factor for relapse in patients with clinically localized prostate cancer

Regenerating islet‐derived family, member 4 (REG4, which encodes Reg IV) is a candidate marker for cancer and inflammatory bowel disease. We investigated the potential prognostic role of Reg IV immunostaining in clinically localized prostate cancer (PCa) after radical prostatectomy. Immunohistochemical staining of Reg IV was performed in 98 clinically localized PCa tumors obtained during curative radical prostatectomy. Intestinal and neuroendocrine differentiation was investigated by MUC2 and chromogranin A immunostaining, respectively. The prognostic significance of immunohistochemical staining for these factors on prostate‐specific antigen (PSA)‐associated recurrence was assessed by Kaplan–Meier analysis and a Cox regression model. Phosphorylation of the epidermal growth factor receptor (EGFR) by Reg IV was analyzed by Western blot. In total, 14 (14%) of the 98 PCa cases were positive for Reg IV staining. Reg IV positivity was observed frequently in association with MUC2 (P = 0.0182) and chromogranin A positivity (P = 0.0012). Univariate analysis revealed that Reg IV staining (P = 0.0004), chromogranin A staining (P = 0.0494), Gleason score (P < 0.0001) and preoperative PSA concentration (P = 0.0167) were significant prognostic factors for relapse‐free survival. Multivariate analysis indicated that Reg IV staining (P = 0.0312), Gleason score (P = 0.0014) and preoperative PSA concentration (P = 0.0357) were independent predictors of relapse‐free survival. In the LNCaP cell line, EGFR phosphorylation was induced by the addition of Reg IV‐conditioned medium. These results suggest that Reg IV expression is an independent prognostic indicator of relapse after radical prostatectomy. (Cancer Sci 2008; 99: 1570–1577)
The Motivation Factors and Farmer Group Clusters on Sustainable Horticulture Practices Adoption in Yogyakarta Province

The decision to apply sustainable horticulture practices can be categorized as pro-environment behavior where motivation or needs are one of the determinants of behavior. The objective of this study was to analyze the factor and discover the farmer group compositions and motivation of farmers to adopt sustainable horticultural practices. The surveys involved 350 members of horticulture farmer groups in Yogyakarta Special Region Province, Indonesia. The results of second-order confirmatory factor analysis show the highest score of the underlying subs-construct of motivation construct is social needs (healthy family and group reference). The highest score of the underlying subs-construct of the level of sustainable horticulture practices (SHP) adoption are inputs (organic fertilizer and superior seeds). There are two clusters of SHP adoption and three clusters of motivation. This study provides information to make an effective strategy for extension education that makes farmers adopt sustainable horticulture practices based on their needs (motivation).
Managing Data-Driven Change: A Model of Unintended Deviation

iii Acknowledgements . iv Dedication . v Chapter 1: Introduction . 1 Problem Statement . 1 Research Questions and Thesis Statement . 2 Research Design . 4 Research Objectives . 6 Chapter 2: Literature Review . 8 Introduction to Change Management . 8 Strategy and Change . 9 Resources and Change . 10 Hospitality Gaming and Change . 11 Relevant Topics in Change Management . 13 Conceptualizing Change . 14 Social Resources as Competitive Advantage . 17 Knowledge Management, Networks, and Structures . 18 Data-driven change . 21 Big Data Analytics . 22 Data and Decision Making . 24 Social and Technological complexity . 27 Difficulty of Change. 28 Resistance . 28 Culture . 29
Multi-objective Genetic Algorithm for Optimal Power Flow Including Voltage Stability

A MOGA for solving the multi-objective optimal power flow (OPF) problem is proposed in this paper. In this method, in the genetic population, the optimization variables are represented in their natural form. The algorithm ensures non-dominated solutions and simultaneously maintains diversity among the non-dominated solutions. The new algorithm applied to an IEEE 30 bus system. The Pareto-optimal front obtained from MOGA is compared with reference Pareto front which is obtained with multiple runs. This paper shows the effectiveness of the proposed algorithm.
Relationships among Visual Awareness, Reaction Time, and Lateralized Readiness Potential in a Simple Reaction Time Task under the Backward Masking Paradigm

The goal of the present study was to examine whether a backward masking paradigm, in which a prime and a mask stimuli were consecutively presented with a short stimulus onset asynchrony affected the time needed for either the perceptual or motor stages of processing and the simple reaction times. The times needed for the perceptual and motor stages were evaluated by measuring the stimulus-locked and response-locked lateralized readiness potentials. The results showed that the onset of the stimulus-locked lateralized readiness potentials under the backward masking paradigm took place earlier than it did under the condition of a mask stimulus presented alone, whereas the onset of the response-locked lateralized readiness potentials did not significantly differ under different stimulus conditions. These results suggested that the participants responded to the masked prime stimulus despite being unaware of the prime stimulus. This may have been mediated by facilitation of the perceptual rather than motor stages.
Traumatic experiences and psychological reactions among women in Bosnia during the war

Internally displaced women (N = 77) in Bosnia were interviewed before and after participating in group psychotherapy during the war in 1994 and 1995 to gain background information and assess stress exposure and stress reactions. Nearly all the women had experienced loss of family members, many acts of violence and mental health impairment. The participants had high scores on a symptom scale, in terms of intrusive, avoidance and arousal symptoms and somewhat lower on depression/powerlessness items. After participating in short‐term group therapy they reported significant reduction in symptoms. The women who had experienced most traumatic events and had most symptoms, reported greatest reduction in symptomatology. Some of the implications of the findings are discussed and it is concluded that group therapy may be helpful in war conditions, even though traditional preconditions for psychotherapy are not present.
Research on taxi drivers' passenger hotspot selecting patterns based on GPS data: A case study in Wuhan

Taxis are the most important components for public transit systems. The model of taxis is more flexible and convenient for passengers compared to other transit model like buses or railway. However, the dynamic of taxi locations will have influence on transit efficiency. Therefore, the hotspot selecting patterns when unoccupied with regards to different income level drivers were investigated in this study. Two month GPS data of 7200 taxis in Wuhan was used as the data samples. The Wuhan City was firstly Mapped Meshing and divided into 4623 grids. After preprocessing the taxi GPS data and taxi drivers' income level classification (top, ordinary and bottom), the pickup points were filtered and matched with all these grids. Heat and grid probability for passenger demand hotspot were proposed and analyzed in this study. The results showed that the correlation value between top drivers and heat are not always higher than ordinary taxi drivers but the correlation value between grid probability and top taxi drivers are always high at all time slots. The finding of this study reveals that the high income taxis drivers have the high ability for cruising to the closed hotspot having high grid probability compared with middle or low income drivers. It therefore recommended that, if such experience could be represented and learned by other taxi drivers, the efficiency of taxi transit systems will be improved. Furthermore, if the information of real time heat and grid probability of hotspot could be broadcasted to taxi drivers, it will be beneficial for taxi transit systems as well.
Epidemiology of drug‐resistant malaria in Republic of Congo: using molecular evidence for monitoring antimalarial drug resistance combined with assessment of antimalarial drug use

In Congo, urgent efforts are needed to help with the revision of the national antimalarial drug policy. Despite its high resistance level, chloroquine (CQ) is still extensively used as the first‐line treatment for uncomplicated Plasmodium falciparum malaria. The study was conducted in children under 5 years with uncomplicated malaria in Pointe‐Noire and Brazzaville, the two largest cities that contain approximately 60% of the population of Congo. We investigated by polymerized chain reaction and sequencing methods the frequency distribution of molecular markers for antimalarial drug resistance, including mutations in P. falciparum chloroquine resistance transporter (pfcrt) gene associated with CQ resistance and mutations in dihydrofolate reductase (dhfr) and dihydropteroate synthetase (dhps) genes conferring resistance to sulphadoxine/pyrimethamine (SP) among pre‐treatment P. falciparum isolates, as well as assessing antimalarial drug use in the community. pfcrt (K76T) mutation was present in most isolates (96.4%, n = 138) and high frequency (69.2%, n = 133) of triple‐mutant dhfr‐S108N, N51I, C59R was observed. The quintuple mutant (dhfr‐S108N, N51I, C59R and dhps‐A437G or S436A, K540E) considered as molecular marker for SP treatment failure was not found because dhps‐K540E mutation was absent in isolates tested; this is a clear evidence for the excellent efficacy of SP that we previously described in the same population. The complete absence of the dhps‐K540E mutation is a deterrent component for using this molecular marker as an early warning tool for SP resistance testing in that population. Poor compliance issues related to the antimalarial drug use including inappropriate manufacturing practices reported in this study require intensive attention and should be taken into account when implementing drug policy change. If Congo changes its treatment policy from CQ to SP monotherapy, this will not last long. The strategy of combining SP with other affordable and effective antimalarial drugs such as the artemisinin derivatives to improve efficacy and to delay the development of parasite resistance is essential.
In-vivo Validation of a Stent Implantation Numerical Model

A large deformation finite element model for the patient-specific prediction of stent implantation is presented as a potential tool to assist clinicians. The intervention simulation includes the complete stent deployment under balloon inflation and deflation in the artery. This paper describes the proposed model and presents an in-vivo validation of the model using pre- and post-intervention data from a patient who underwent stent implantation. Predicted cross-section areas at different artery positions are compared to post-intervention measurements. This work demonstrated the model's potential to become a relevant tool for predicting the arterial response to the intervention.
Deficits on a probabilistic response-reversal task in patients with pediatric bipolar disorder.

OBJECTIVE Patients with bipolar disorder become hyperhedonic when manic and anhedonic when depressed; therefore, it is important to test whether patients with bipolar disorder show deficits on behavioral paradigms exploring reward/punishment mechanisms. METHOD A probabilistic response-reversal task was administered to 24 bipolar children and 25 comparison subjects. RESULTS Patients made more errors during probabilistic reversal, took longer to learn the new reward object, and were less likely to meet the learning criterion. CONCLUSIONS Children with bipolar disorder may have a reversal learning deficit.
Supply chain inventory model for perishable items under delayed payment

Abstract This paper attempts to create a supply chain inventory model for perishable goods that simultaneously considers delayed payment and shortage. For this purpose, a two-layer supply chain system was described, and a perishable goods inventory model was created for two types of grace periods. Then, the optimal distribution cycle and quantity were computed in the mode of single ordering and multiple distributions. Finally, the author investigated the effect of unit shortage cost, deterioration rate and grace period on the total cost of the supply chain. The model was validated through a case study. The research findings provide valuable references for inventory management of supply chain enterprises.
Temperature-sensitive multicellular mutants of Wangiella dermatitidis

Three temperature-sensitive morphological mutants of Wangiella dermatitidis were isolated and characterized. The mutants grew in the yeastlike morphology at the permissive temperature (25 degrees C) but expressed a multicellular (Mc) phenotype at the restrictive temperature (37 degrees C). Cultures of Mc 2 and 3 incubated at the restrictive temperature showed rapid reductions in the percentage of budded cells in the population. In contrast, budding continued for several generations in cultures of Mc 1. Incubation of cultures of Mc 2 and 3 at the restrictive temperature for 48 h resulted in nearly total conversion of yeastlike cells to the multicellular form; about 50% of the cells of Mc 1 had converted to multicellular forms after 48 h at the restrictive temperature. Studies using radiolabeled compounds documented that DNA, RNA, and protein synthesis continued at the restrictive temperature. The results suggest that multicellularity is the result of inhibition of bud emergence and cell separation without inhibition of growth nuclear division, and cytokinesis.
Forecasting of Changes of Companies Financial Standings on the Basis of Self-Organizing Maps

The multivariate discriminate models have been used in area of bankruptcy analysis for many years. In this paper we suggest to conjunct the principles of traditional discriminate bankruptcy models with modern methods of machine learning. We propose the forecasting model based on Self-organizing maps, where inputs are indicators of multivariate discriminate model. Accuracy of forecasting is improved via changing weights with supervised learning type ANN. We’ve presented results of testing of this model in various
Clinical characteristics of psychiatrically referred adolescent outpatients with substance use disorder.

OBJECTIVE There is increasing interest in the developmental relationship of psychopathology and substance use disorders (SUD) in youths. Because the bulk of literature is focused in inpatient or incarcerated youths, inferences and generalizations are limited in outpatient settings. The clinical characteristics of psychiatrically referred outpatients were studied to determine whether differences existed in the nature and severity of comorbid psychiatric disorders when substance abuse was involved. METHOD All diagnoses were derived from structured psychiatric interviews completed on all youths on intake assessment. Adolescents with an identified SUD (n = 38) were compared with those without SUD (n = 321) on a number of variables including past and current psychopathology, cognitive and school functioning, and overall impairment. RESULTS Eleven percent of referred outpatients (mean age = 15.9 +/- 1.3 years) met full criteria for a SUD by parental report. Controlling for age, adolescents with SUD had higher risk for mood and disruptive behavioral disorders compared with psychiatric controls. In the majority of cases, the onset of psychopathology preceded the onset of SUD by at least 1 year. The group with SUD also had lower overall functioning and more school dysfunction and psychiatric hospitalizations than their non-SUD peers. CONCLUSIONS Despite the small number of adolescents with SUD in this sample, these data indicate that SUD is common in outpatient psychiatry referrals. Youths with SUD appear to be at increased risk for more psychopathology and dysfunction in a number of domains.