Miracle-dz/UniFAR-FTUs huggingface dataset:
A Modified Metaheuristic Algorithm for Opinion Mining

mining is a recent discipline combining Information Retrieval and Computational Linguistics which is concerned with the opinion a document expresses and not just with the topic in the document. Online forums, newsgroups, blogs, and specialized sites provide voluminous information feeds from where opinions can be retrieved. Opinion's polarity is established through application of machine learning techniques for classification of textual reviews as either a positive or negative class. In this paper, it is proposed to extract the feature set from reviews using Inverse document frequency and the reviews are classified as positive or negative using Bagging algorithms. The proposed method is evaluated using a subset of Internet Movie Database (IMBd).
Determining the possible building blocks of the Earth and Mars

Abstract— To determine the possible building blocks of the Earth and Mars, 225,792,840 possible combinations of the bulk oxygen isotopic and chemical compositions of 13 chondritic groups at 5% mass increments were examined. Only a very small percentage of the combinations match the oxygen isotopic composition, the assumed bulk FeO concentration, and the assumed Fe/Al weight ratio for the Earth. Since chondrites are enriched in silicon relative to estimates of the bulk Earth, none of the combinations fall near the terrestrial magmatic fractionation trend line in Mg/Si‐Al/Si space. More combinations match the oxygen isotopic composition and the assumed bulk FeO concentration for Mars. These combinations fall near the trend for shergottite meteorites in Mg/Si‐Al/Si space. One explanation for the difficulty in forming Earth out of known chondrites is that the Earth may be composed predominately of material that did not survive to the present day as meteorites. Another explanation could be that significant amounts of silicon are sequestered in the core and/or lower mantle of the Earth.
Cat-Scratch Disease: Bacteria in Skin at the Primary Inoculation Site

Cat-scratch disease is a zoonotic infection characterized by a skin papule at the site of the scratch followed by regional lymphadenitis. Recently, small gram-negative pleomorphic bacilli were demonstrated in sections of lymph node from patients with the disease. We now report identical bacteria in the primary inoculation site of three patients with cat-scratch disease. Lymph nodes from two of these patients also contained the same bacilli. Identical bacteria in both skin and lymph nodes from these patients are further evidence that the bacilli are the cause of cat-scratch disease. In early infections, biopsy of the primary site of inoculation and demonstration of bacilli may replace excision and histologic examination of lymph node in establishing the diagnosis of cat-scratch disease. (JAMA1984;252:928-931)
A novel subcutaneous infusion delivery system based on osmotic pump: in vitro and in vivo evaluation

Abstract An economical, convenient portable drug delivery system combining osmotic pump with subcutaneous infusion was developed, which was composed of three primary components: water chamber, osmotic pump chamber and support base. Ceftriaxone sodium (CRO) was selected as the model drug and osmotic pump tablets were prepared. The influence of osmotic agents on drug release profiles was evaluated. As the adjustment made by the osmotic agents was limited, the compositions of semipermeable membrane were investigated to determine significant associations of factors based on orthogonal design. The in vitro release profiles of the optimum formulation achieved to the predetermined value (15 ± 3 min for the initial release time Ti and 5.75 ± 0.25 h for the extent release time Te). The pharmacokinetic profiles of this drug delivery system were evaluated in Beagle dogs. In vivo results demonstrated that the osmotic pump subcutaneous infusion administration was equivalent to intravenous injection administration in terms of bioavailability. Moreover, constant drug plasma levels with minimized fluctuations could be achieved with this osmotic pump subcutaneous infusion system, compared with intravenous injection.
Powered mobility device use: participation and accessibility

This thesis elucidates the use of powered mobility devices in a Swedish context. The overall aim was to increase and deepen the knowledge on powered mobility device use in relation to participation and accessibility in different environments and among different user groups, with a specific focus on independence and autonomy. An additional aim was to contribute to the knowledge base regarding the optimization of use of such devices. The thesis is based on four studies in which different research approaches were applied through the combination of different types of data in order to interpret the complexity of powered mobility device use. Quantitative, qualitative and mixed methods were utilized. The first study was a prospective cohort study in which data was collected using structured interviews at baseline and two follow-ups. The second study was an exploratory multiple longitudinal case study. A focus-group methodology with a descriptive design was used in the third study. The fourth study was a cross-sectional study based on survey data collected from people with spinal cord injury. The main contribution of the studies that constitute the empirical basis of this thesis is that the purpose of providing people with powered mobility devices is mostly fulfilled in that such devices provide their users’ with greater opportunities for participation. Nevertheless, there are also problems in terms of accessibility in various environmental arenas that have an impact on mobility. An additional important contribution is that the results show that the experiences of users of powered mobility devices should be taken seriously as they convey different aspects of how the use of such devices could be optimized. In conclusion, this thesis contributes to our understanding of the use of powered mobility devices and has the potential to optimize independence in terms of mobility and participation among users of such devices. Finally, the results have practical implications for occupational therapy in the provision of powered mobility devices. Likewise, this new knowledge about the needs of powered mobility device users in terms of accessibility are of importance to politicians, professionals and other stakeholders engaged in housing provision and physical planning.
DNA Polymerases from RNA Tumor Viruses and Human Cells: Inhibition by Polyuridylic Acid

Polyuridylic acid inhibited DNA polymerases purified from three species of oncornaviruses as well as three out of seven DNA polymerases purified from cells. Viral and cellular DNA polymerases could not be distinguished by polyuridylic acid inhibition, but were easily distinguished by their template preferences in the presence of magnesium.
Situation-aware mobile health monitoring

Recent advances in mobile computing coupled with the widespread availability of inexpensive mobile devices are the key motivating factors for the development of mobile health monitoring systems. However, to leverage the full potential of such systems for continuous and real time monitoring, there are a number of challenges that need to be addressed. This paper proposes a situation-aware mobile health monitoring framework that aims to increase not only the accuracy in identifying the occurring health conditions but also the cost-efficiency of running algorithms (e.g. the activity recognition classifier) using a situation-aware adaptation technique. The proposed framework integrates high level knowledge (i.e. user activity) with low level sensory data (e.g. heart rate) in situation reasoning and data fusion. Such holistic situational information can significantly improve accuracy of clinical decision making and self-management of chronic diseases. The implementation and evaluation of the framework for a health monitoring application is described.
(1R*,2S*,4S*,5R*)-Cyclohexane-1,2:4,5-tetracarboxylic dianhydride

The title compound, C10H8O6, a promising raw material to obtain colorless polyimides which are applied to microelectronic and optoelectronic devices, adopts a folded conformation in which the dihedral angle between the two anhydro rings is 55.15 (8)°. The central six-membered ring assumes a conformation intermediate between boat and twist-boat. In the crystal, molecules are linked by weak C—H⋯O interactions, forming a layer parallel to the bc plane.
The in uence of autonomous and controlling motives on physical activity intentions within the Theory of Planned Behaviour

Objectives. This study aimed to examine how general motives from self-determination theory (SDT; Deci & Ryan, 1985) in uence intentions to engage in physical activity within the Theory of Planned Behaviour (TPB; Ajzen, 1985). It was hypothesized that the general motives will in uence intentions only when mediated by the speci c cognitions of attitude, subjective norms and perceived behavioural control (PBC) from the TPB.
Rh-Ni/SBA-15 prepared by two solvents method as stable catalysts for the dry reforming of methane at high pressure

The effect of Rh addition on the catalytic performance of Ni/SBA-15 catalysts was studied in the dry reforming of methane. The SBA-15 silica support was synthesized in large quantities and the metals were deposited using the two solvents impregnation method. The properties of the calcined, reduced and spent catalysts were studied using the N2 sorption isotherms, XRD, H2-TPR, SEM, TEM and Raman spectroscopy. It was shown that the SBA-15 porous structure was maintained throughout the study with high dispersion of the metals inside the pores. The Ni/SBA-15 catalyst was stable for more than 90h of testing owing to the porous structure of the support that stabilizes the particles and prevents their sintering; thus the promotion with 0.5 wt% Rh showed a minor improvement of the catalytic stability. The 0.5Rh-Ni/SBA-15 catalyst was also stable at 650°C and 9 bars for more than 200 min.
A Maternal Smad Protein Regulates Early Embryonic Apoptosis in Xenopus laevis

ABSTRACT We identified cDNAs encoding the Xenopus Smad proteins most closely related to mammalian Smad8, and we present a functional analysis of this activity (also referred to recently as xSmad11). Misexpression experiments indicate that xSmad8(11) regulates pathways distinct from those regulated by the closely related xSmad1. Embryos that develop from eggs depleted of xSmad8(11) mRNA fail to gastrulate; instead, at the time of gastrulation, they initiate a widespread program of apoptosis, via a CPP32/caspase 3 pathway. Embryos that avoid this fate display gastrulation defects. Activation of apoptosis is rescued by expression of xSmad8(11) but not xSmad1. Our results demonstrate an embryonic requirement for Smad8(11) activity and show that a maternally derived Smad signaling pathway is required for gastrulation and for mediating a cell survival program during early embryogenesis. We suggest that xSmad8(11) functions as part of a maternally derived mechanism shown previously by others to monitor Xenopus early embryonic cell cycles.
Dynamic Privacy in a Smart House Environment

A smart house can be regarded as a surveillance environment in which the person being observed carries out activities that range from intimate to more public. What can be observed depends on the activity, the person observing (e.g. a carer) and policy. In assisted living smart house environments, a single privacy policy, applied throughout, would be either too invasive for an occupant, or too restrictive for an observer, due to the conflicting goals of surveillance and private environments. Hence, we propose a dynamic method for altering the level of privacy in the environment based on the context, the situation within the environment, encompassing factors relevant to ensuring the occupant's safety and privacy. The context is mapped to an appropriate level of privacy, which is implemented by controlling access to data sources (e.g. video) using data hiding techniques. The aim of this work is to decrease the invasiveness of the technology, while retaining the purpose of the system.
Optimizing dependency parsing throughput

Dependency parsing is considered a key technology for improving information extraction tasks. Research indicates that dependency parsers spend more than 95% of their total runtime on feature computations. Based on this insight, this paper investigates the potential of improving parsing throughput by designing feature representations which are optimized for combining single features to more complex feature templates and by optimizing parser constraints. Applying these techniques to MDParser increased its throughput four fold, yielding Syntactic Parser, a dependency parser that outperforms comparable approaches by factor 25 to 400.
Improvement in the performance of deep neural network model using learning rate

This The core aim of this paper is to find out the accuracy of SDN network, in this we applied different approaches to increase the efficiency of the network, so that the performance as well as the accuracy will improve Different classifier are applied to form a model, in which pre processing and transformation are the essential phases before developing a model. After analyzing the classifier like NaiveBayes, Support Vector Machine, J48 and Deep Neural Network we found our Deep Neural Network with learning rate variation prove to be the best classifier among the all. In our work we are using the basic ten features out of the several features of NSL-KDD Dataset that are useful to build the network to predict the attacks in the intrusion detection system
Safety-aware network deployment for 3G cellular systems

Cellular communications has entered a booming era. As an evolution of the second generation cellular network that is mainly used for voice communications, the third generation (3G) network provides an infrastructure for higher data rates and better multimedia services. However, the RF-radiation exposure from 3G base stations has become a public concern. Studies have shown that the 3G base station signals have a more significant radioactive effect on nearby residents than the GSM base stations. When 3G networks are deployed, the carriers should try their best to keep some important sites such as schools, hospitals, or residence buildings to be at a safe distance away from the base stations. In some cases, it may be possible that, no matter how a network is deployed, not all of the sites could have a safe distance away from the base stations. The problem to be solved in this paper is referred to as the maximum safe sites problem: given a planned network with certain capacity, a safe distance, and a set of sites, find a deployment of the planned network such that the number of safe sites is maximized. This paper presents an efficient solution to the maximum safe sites problem. Specifically, the maximum safe sites problem can be solved in O(n/sup 2/logn) time if n sites are to be considered.
FTY720-Enhanced T Cell Homing Is Dependent on CCR2, CCR5, CCR7, and CXCR4: Evidence for Distinct Chemokine Compartments1

FTY720 stimulates CCR7-driven T cell homing to peripheral lymph nodes (LN) by direct activation of sphingosine 1-phosphate receptors, along with the participation of multidrug transporters, 5-lipoxygenase, and G protein-coupled receptors for chemokines. In this study, we demonstrate that FTY720 also directly stimulates in vitro T cell chemotaxis to CCR2-CCL2, but not to a variety of other chemokines, including CCR5-CCL3/4/5 and CXCR4-CXCL12. FTY720 influences CCR2-CCL2-driven migration through activation of the multidrug transporters, Abcb1 and Abcc1, and through 5-lipoxygenase activity. In vivo administration of FTY720 induces chemokine-dependent migration of T cells in the thymus, peripheral blood, LN, and spleen. The CCR7 and CCR2 chemokine ligands are required for both T cell sequestration in LN and thymic T cell egress following FTY720 administration. Furthermore, FTY720 administration uncovers a requirement for CXCR4 ligands for LN homing, but not for thymic egress, and CCR5 for thymic egress, but not LN homing. FTY720-driven splenic and peripheral blood T cell egress are both independent of CCR2, CCR5, CCR7, or CXCR4. These results indicate that FTY720- and sphingosine 1-phosphate receptor-stimulated T cell migration are dependent on the restricted usage of chemokine receptor-ligand pairs within discrete anatomic compartments.
Single-channel speech-music separation using NMF for automatic speech recognition

In this study, single-channel speech source separation is carried out to separate the speech from the background music, which degrades the speech recognition performance especially in broadcast news transcription systems. Since the separation is done using single observation of the source signals, the sources have to be previously modeled using training data. Non-negative Matrix Factorization (NMF) methods are used to model the sources. In order to model the source signals, different training data sets, which contain different music and speech data, are created and the effect of the training data sets are analyzed in this study. The performances of the methods are measured not only using separation performance measure but also with speech recognition performance measures.
Identiﬁcation and Characterization of Novel Helicobacter pylori apo -Fur-Regulated Target Genes

In Helicobacter pylori , the ferric uptake regulator (Fur) has evolved additional regulatory functions not seen in other bacteria; it can repress and activate different groups of genes in both its iron-bound and apo forms. Because little is understood about the process of apo -Fur repression and because only two apo -Fur-repressed genes ( pfr and sodB ) have previously been identiﬁed, we sought to expand our understanding of this type of regulation. Utilizing published genomic studies, we selected three potential new apo -Fur-regulated gene targets: serB , hydA , and the cytochrome c 553 gene. Transcriptional analyses conﬁrmed Fur-depen-dent repression of these genes in the absence of iron, as well as derepression in the absence of Fur. Binding studies showed that apo -Fur directly interacted with the suspected hydA and cytochrome c 553 promoters but not that of serB , which was subsequently shown to be cotranscribed with pfr ; apo -Fur-dependent regulation occurred at the pfr promoter. Alignments of apo -regulated promoter regions revealed a conserved, 6-bp consensus sequence (AAATGA). DNase I footprinting showed that this sequence lies within the protected regions of the pfr and hydA promoters. Moreover, mutation of the sequence in the pfr promoter abrogated Fur binding and DNase protection. Likewise, ﬂuorescence anisotropy studies and binding studies with mutated consensus sequences showed that the sequence was important for apo -Fur binding to the pfr promoter. Together these studies expand the known apo
Intelligent tutoring systems for programming education: a systematic review

A variety of intelligent tutoring systems have been created for the purpose of teaching computer programming. Most published literature focuses on systems that have been developed to teach programming within tertiary courses. A majority of systems have been developed to teach introductory programming concepts; other systems tutor more specific aspects of programming like scope or recursion. Literature reports that these systems address many of the difficulties associated with teaching programming to novices; however, individual systems vary greatly, and there is a large range of supplementary features developed in these systems. Most intelligent programming tutors involve some form of interactive programming exercises, but the use of supplementary features like plans, quizzes and worked solutions vary greatly between different systems. This systematic review reports key information about existing systems and the prevalence of different features within them. An overview of how supplementary features are integrated into these systems is given, along with implications for how intelligent programming tutors could be improved by supporting a wider range of supplementary features.
Familiarity modulates mirror neuron and mentalizing regions during intention understanding

Recent research suggests that the inference of others' intentions from their observed actions is supported by two neural systems that perform complementary roles. The human putative mirror neuron system (pMNS) is thought to support automatic motor simulations of observed actions, with increased activity for previously experienced actions, whereas the mentalizing system provides reflective, non‐intuitive reasoning of others' perspectives, particularly in the absence of prior experience. In the current fMRI study, we show how motor familiarity with an action and perceptual familiarity with the race of an actor uniquely modulate these two systems. Chinese participants were asked to infer the intentions of actors performing symbolic gestures, an important form of non‐verbal communication that has been shown to activate both mentalizing and mirror neuron regions. Stimuli were manipulated along two dimensions: (1) actor's race (Caucasian vs. Chinese actors) and (2) participants' level of experience with the gestures (familiar or unfamiliar). We found that observing all gestures compared to observing still images was associated with increased activity in key regions of both the pMNS and mentalizing systems. In addition, observations of one's same race generated greater activity in the posterior pMNS‐related regions and the insula than observations of a different race. Surprisingly, however, familiar gestures more strongly activated regions associated with mentalizing, while unfamiliar gestures more strongly activated the posterior region of the pMNS, a finding that is contrary to prior literature and demonstrates the powerful modulatory effects of both motor and perceptual familiarity on pMNS and mentalizing regions when asked to infer the intentions of intransitive gestures. Hum Brain Mapp, 2011. © 2010 Wiley‐Liss, Inc.
Advances in Brief Complex Regulation of Membrane-Type Matrix Metalloproteinase Expression and Matrix Metalloproteinase-2 Activation by Concanavalin A in MDA-MB-231 Human Breast Cancer Cells 1

Matrix Metalloproteinase-2 (MMP-2) is secreted as a zymogen, the activation of which has been associated with metastatic progression in human breast cancer (HBC). Concanavalin A (Con A) has been found to induce activation of MMP-2 in invasive HBC cell lines. Con A effects on the expression of mRNA for membrane-type matrix metalloproteinase (MT-MMP), a newly described cell surface-associated MMP, showed a close temporal correlation with induction of MMP-2 activation. It is surprising that MT-MMP mRNA is constitutively present in the iininduced MDA-MB-231 cell, despite a lack of MMP-2 activation. We have used actinomycin D to demonstrate a partial requirement for de novo gene expression in the induction of MMP-2 activation by Con A in MDA-MB231 HBC cells. Furthermore, this transcriptional response to Con A appeared to require the continued presence of Con A for its manifestation. The nontranscriptional component of the Con A induction manifests rapidly, is quite substantial, and persists strongly despite actinomycin D abrogation of both constitutive and Con A-induced MT-MMP. Cycloheximide analyses suggest that protein synthesis may be involved in this rapid transcription-independent response. These studies suggest that Con A induces MMP-2-activation in part by up-regulation of MT-MMP expres sion but has a more complicated mode of action, involving additional nontranscriptional effects, which apparently require protein synthesis.