Miracle-dz/UniFAR-FTUs huggingface dataset:
Online Anomaly Detection by Improved Grammar Compression of Log Sequences

Nowadays, log sequences mining techniques are widely used in detecting anomalies for Internet services. The state-ofthe-art anomaly detection methods either need significant computational costs, or require specific assumptions that the test logs are holding certain data distribution patterns in order to be effective. Therefore, it is very difficult to achieve real time responses and it greatly reduces the effectiveness of these mechanisms in reality. To address these issues, we propose an innovative anomaly detection strategy called CADM. In CADM, the relative entropy between test logs and normal logs is exploited to discover the anomalous levels. Instead of calculating the relative entropy based on certain predefined data distribution models, our solution inspects the relationship between relative entropy and compression size with an improved grammar-based compression method. No assumptions are needed. In addition, our mechanism has excellent scalability with only O(n) computational complexity. It can generate the detection results on the fly. Experimental analysis with both synthetic and real world logs proves that CADM is superior to the other methods. It can achieve very high anomaly detection accuracy with the minimal computational overhead. It is suitable for log mining tasks and can be applied on a broad variety of application fields.
The FORS Deep Field Spectroscopic Survey

We present a catalogue and atlas of low-resolution spectra of a well defined sample of 341 objects in the FORS Deep Field. All spectra were obtained with the FORS instruments at the ESO VLT with essentially the same spectroscopic set-up. The observed extragalactic objects cover the redshift range 0. 1t o 5.0. 98 objects are starburst galaxies and QSOs at z > 2. Using this data set we investigated the evolution of the characteristic spectral properties of bright starburst galaxies and their mutual relations as a function of redshift. Significant evolutionary effects were found for redshifts 2 < z < 4. Most conspicuous are the increase of the average C IV absorption strength, of the dust reddening, and of the intrinsic UV luminosity, and the decrease of the average Lyα emission strength with decreasing redshift. In part the observed evolutionary effects can be attributed to an increase of the metallicity of the galaxies with cosmic age. Moreover, the increase of the total star-formation rates and the stronger obscuration of the starburst cores by dusty gas clouds suggest the occurrence of more massive starbursts at later cosmic epochs.
Systemic Immune Activation Leads to Neuroinflammation and Sickness Behavior in Mice

Substantial evidence indicates an association between clinical depression and altered immune function. Systemic administration of bacterial lipopolysaccharide (LPS) is commonly used to study inflammation-associated behavioral changes in rodents. In these experiments, we tested the hypothesis that peripheral immune activation leads to neuroinflammation and depressive-like behavior in mice. We report that systemic administration of LPS induced astrocyte activation in transgenic GFAP-luc mice and increased immunoreactivity against the microglial marker ionized calcium-binding adapter molecule 1 in the dentate gyrus of wild-type mice. Furthermore, LPS treatment caused a strong but transient increase in cytokine levels in the serum and brain. In addition to studying LPS-induced neuroinflammation, we tested whether sickness could be separated from depressive-like behavior by evaluating LPS-treated mice in a panel of behavioral paradigms. Our behavioral data indicate that systemic LPS administration caused sickness and mild depressive-like behavior. However, due to the overlapping time course and mild effects on depression-related behavior per se, it was not possible to separate sickness from depressive-like behavior in the present rodent model.
Nurturing Natures

This book provides an indispensable account of current understandings of children’s emotional development. Integrating the latest research findings from areas such as attachment theory, neuroscience and developmental psychology, it weaves these into a readable and easy to digest text. It provides a tour of the most significant influences on the developing child, always bearing in mind the family and social context. It looks at key developmental stages, from life in the womb to the pre-school years and right up until adolescence, whilst also examining how we develop key capacities such as language, play and memory. Issues of nature and nurture are addressed and the effects of different kinds of early experiences are unpicked, looking at both individual children and larger-scale longitudinal studies. Psychological ideas and research are carefully integrated with those from neurobiology and understandings from other cultures to create a coherent and balanced view of the developing child in context. Nurturing Natures integrates a wide array of complex academic research from different disciplines to create a book that is not only highly readable but also scientifically trustworthy. Full of fascinating findings, it provides answers to many of the questions people really want to ask about the human journey from conception into adulthood.
A hybrid approach for vision-based outdoor robot localization using global and local image features

Vision-based robot localization in outdoor environments is difficult because of changing illumination conditions. Another problem is the rough and cluttered environment which makes it hard to use visual features that are not rotation invariant. A popular method that is rotation invariant and relatively robust to changing illumination is the Scale Invariant Feature Transform (SIFT). However, due to the computationally intensive feature extraction and image matching, localization using SIFT is slow. On the other hand, techniques which use global image features are in general less robust and exact than SIFT, but are often much faster due to fast image matching. In this paper, we present a hybrid localization approach that switches between local and global image features. For most images, the hybrid approach uses fast global features. Only in difficult situations, e.g. containing strong illumination changes, the hybrid approach switches to local features. To decide which features to use for an image, we analyze the particle cloud of the particle filter that we use for position estimation. Experiments on outdoor images taken under varying illumination conditions show that the position estimates of the hybrid approach are about as exact as the estimates of SIFT alone. However, the average localization time using the hybrid approach is more than 3.5 times faster than using SIFT.
PDA design based on embedded Linux

With the further development of the computer network, the revolution of the OS and the popularization of network transmission technology, PDA has been an important upsurge in IT business for its small size, low energy consumption, powerful functions and easy exploiting. Meanwhile, the embedded system technology has infiltrated into all fields of the society. Linux has more development space in embedded systems thanks to its great performance in high end servers and the characteristic of open source and service-oriented. Therefore, PDA development based on embedded Linux has been the hotspot for many researchers. In order to further exploit the development process of PDA and improve the design in the practical level, we studied the development process of the PDA tools on the ARM-Linux platform in the case of address book design. This paper first introduced the development overview and main application of PDA in various fields, then presented the embedded Linux development platform and the experiment setup, furthermore, we chose Qt as the graphics development toolkit for this paper and made detailed description for the design and implementation of the address book.
DNA-guided establishment of nucleosome patterns within coding regions of a eukaryotic genome

A conserved hallmark of eukaryotic chromatin architecture is the distinctive array of well-positioned nucleosomes downstream from transcription start sites (TSS). Recent studies indicate that trans-acting factors establish this stereotypical array. Here, we present the first genome-wide in vitro and in vivo nucleosome maps for the ciliate Tetrahymena thermophila. In contrast with previous studies in yeast, we find that the stereotypical nucleosome array is preserved in the in vitro reconstituted map, which is governed only by the DNA sequence preferences of nucleosomes. Remarkably, this average in vitro pattern arises from the presence of subsets of nucleosomes, rather than the whole array, in individual Tetrahymena genes. Variation in GC content contributes to the positioning of these sequence-directed nucleosomes and affects codon usage and amino acid composition in genes. Given that the AT-rich Tetrahymena genome is intrinsically unfavorable for nucleosome formation, we propose that these “seed” nucleosomes—together with trans-acting factors—may facilitate the establishment of nucleosome arrays within genes in vivo, while minimizing changes to the underlying coding sequences.
Familiarity with Sexual Assault and Its Relationship to the Effectiveness of Acquaintance Rape Prevention Programs

This study examined the effectiveness of two rape prevention programs on rape-supportive beliefs among college students. The effectiveness was examined in terms of whether or not the students knew someone who had been sexually assaulted, knew someone who had committed a sexual assault, or were themselves a victim of sexual assault. The participants were divided into three groups. One group participated in a didactic rape prevention program involving primarily lecture and video instruction. The second group participated in an experiential rape prevention program utilizing improvisational theater. The third group was the control group. The 55 participants completed two attitude scales developed by Burt (1980): Adversarial Sexual Beliefs (ASB) and Rape Myth Acceptance (RMA). They then participated in their workshop and took the attitude scales again as a post-treatment test Two weeks later, the participants took a follow-up post-treatment test using the same attitude scales. Participants who had been victims of sexual assault scored significantly lower than non-victims in the ASB and RMA across all groups. It was also found that participants who had any previous experience with sexual assault, such as familiarity with a victim or an offender, scored significantly lower in rape-supportive beliefs after participating in the didactic program than participants who had no previous experience with sexual assault.
Response patterns and force relations of monkey spinal interneurons during active wrist movement.

The activity of C6-T1 spinal cord neurons was recorded in three macaques while they generated isometric wrist flexion and extension torques in visually guided step-tracking tasks. Electromyographic activity (EMG) was recorded in </=12 independent forearm muscles. Spike-triggered averages (STAs) of rectified and unrectified EMG were used to classify neurons into four groups. Motoneurons (MNs) had a clear postspike motor unit signature in the unrectified STA of one muscle. Premotor interneurons (PreM-INs) had postspike effects in at least one muscle, with onset latencies of >/=3.5 ms from the trigger. Synchrony interneurons (Sy-INs) were non-PreM-Ins that had spike-related features with latencies <3.5 ms in at least one muscle. Unidentified interneurons (U-INs) showed no features in any of the STAs. A total of 572 task-related spinal neurons were studied; 29 cells were MNs, 97 PreM-INs, 32 Sy-INs, and 414 U-INs. MNs were activated predominantly in a tonic fashion during the ramp-and-hold torques and were active in one direction only. The most common response pattern for interneurons, irrespective of their class, was phasic-tonic activity, followed by purely tonic and purely phasic activity. Most interneurons (77%) were bidirectionally active in both flexion and extension. For all classes of interneurons, units with phasic response components tended to be activated first, before torque onset, followed by tonic units. The onset times of PreM-INs relative to onsets of their target muscles were distributed broadly, with a mean of -25 +/- 128 (SD) ms. For most neurons with tonic response components (all MNs, 71% of PreM-INs, 67% of Sy-INs, and 84% of U-INs), activity during the hold period was correlated significantly with the magnitude of static torque exerted by the monkey. The rate-torque regressions generally had positive slopes with higher mean slopes for extension than for flexion. The phasic response components were correlated significantly with rate of change of torque for a smaller percentage of tested PreM-Ins (50%), Sy-INs (83%), and U-INs (77%). In contrast to other premotor neurons [corticomotoneuronal (CM), rubromotoneuronal (RM), and dorsal root ganglion (DRG) afferents] previously characterized under similar conditions, a larger proportion of the spinal PreM-INs were activated after onset of their target muscles, probably reflecting a larger proportion of PreM-INs driven by peripheral input. The rate-torque slopes of PreM-INs tended to be less steep than those of CM and RM cells. Unlike the CM and DRG PreM afferents, which were activated unidirectionally, most spinal PreM-INs showed bidirectional activity, like RM cells.
Cytochrome P450 Gene Variants, Race, and Mortality Among Clopidogrel-Treated Patients After Acute Myocardial Infarction

Background—Clopidogrel is recommended after acute myocardial infarction but has variable efficacy and safety, in part related to the effect of cytochrome P450 (CYP) polymorphisms on its metabolism. The effect of CYP polymorphisms on cardiovascular events among clopidogrel-treated patients after acute myocardial infarction remains controversial, and no studies to date have investigated the association of CYP variants with outcomes in black patients. Methods and Results—Subjects (2732: 2062 whites; 670 blacks) hospitalized with acute myocardial infarction enrolled in the prospective, multicenter TRIUMPH study were genotyped for CYP polymorphisms. The majority of whites (79%) and blacks (64.4%) were discharged on clopidogrel. Among whites, carriers of the loss-of-function CYP2C19*2 allele had significantly increased 1-year mortality (adjusted hazards ratio [HR]: 1.70; confidence interval [CI]: 1.01–2.86; P=0.046) and a trend toward increased rate of recurrent MI (adjusted HR: 2.10; CI: 0.95–4.63; P=0.066). Among blacks, increased 1-year mortality was associated with the gain-of-function CYP2C19*17 allele (adjusted HR for *1/*17 versus *1/*1: 2.02; CI: 0.92–4.44; *17/*17 versus *1/*1: 8.97; CI: 3.34–24.10; P<0.0001) and the CYP1A2*1C allele (adjusted HR for *1/*1C versus *1/*1: 1.89; CI: 0.85–4.22; *1C/*1C versus *1/*1: 4.96; CI: 1.69–14.56; P=0.014). Bleeding events were significantly more common among black carriers of CYP2C19*17 or CYP1A2*1C. Conclusions—Both loss-of-function and gain-of-function CYP polymorphisms affecting clopidogrel metabolism are associated with increased mortality among clopidogrel-treated patients after acute myocardial infarction; the specific polymorphism and the putative mechanism vary according to race.
Pose-robust representation for face verification in unconstrained videos

Face recognition in unconstrained videos has been actively studied with the increasing popularity of surveillance and personal cameras. Compared with the traditional task of face recognition in images, recognizing faces in unconstrained videos is much more challenging due to the large variations in poses, expressions and lighting conditions. To handle varying poses in the videos, in this paper, we propose a two-level representation approach for face verification in unconstrained videos. Specifically, we first recover the full-pose face representation for each video which contains all the pose categories ranging from the most left to the most right profile faces. The missing poses are synthesized using keyframes of known ones. Then, we further propose a cross-pose video pair representation for face verification task, which consists of the similarity scores of all frame-level pairs across two videos. Extensive experiments on the benchmark YouTube Faces (YTF) dataset clearly demonstrate the effectiveness of our proposed method.
Quantal analysis of inhibitory synaptic transmission in the dentate gyrus of rat hippocampal slices: a patch‐clamp study.

1. Synaptically connected neurones were identified in the granule cell layer of slices of 17‐ to 21‐day‐old rat hippocampus. Whole‐cell current recording using the patch‐clamp technique revealed synaptic currents ranging from less than 10 to 200 pA in symmetrical Cl‐ conditions, at a holding potential of ‐50 mV. These currents were blocked by 2 microM‐bicuculline, indicating that they result from the activation of postsynaptic gamma‐aminobutyric acid receptor (GABAA‐receptor) channels. 2. Addition of tetrodotoxin (TTX, 1 microM) resulted in the loss of most currents of more than 40 pA in amplitude. Currents which disappeared after TTX treatment were assumed to be the result of spontaneous presynaptic action potentials. The currents seen in the absence of TTX are referred to as spontaneously occurring inhibitory postsynaptic currents (IPSCs); those remaining in the presence of TTX were defined as miniature IPSCs. 3. Similar currents were observed when recording in the whole‐cell configuration while extracellular stimulation was applied to a nearby neurone. These currents were also completely blocked by 2 microM‐bicuculline and by 0.5 microM‐TTX. They were thus defined as stimulus‐evoked IPSCs. 4. The half rise time of both miniature and stimulus‐evoked IPSCs was fast (less than 1 ms). The time course of decay of both miniature IPSCs and stimulus‐evoked IPSCs could be well fitted with the sum of two exponentials. At a membrane potential of ‐50 mV, the mean decay time constants of the two components were 2.0 +/‐ 0.38 and 54.4 +/‐ 18 ms (mean +/‐ S.D.) for miniature IPSCs (six cells) and 2.2 +/‐ 1.3 and 66 +/‐ 20 ms (three cells) for stimulus‐evoked IPSCs. 5. Stimulus‐evoked IPSCs varied in amplitude from less than ten to hundreds of picoamperes. In eight of eleven cells histograms of IPSC amplitudes showed several clear peaks which, when fitted with the sum of Gaussian curves, were found to be equidistant. This is consistent with the view that stimulus‐evoked IPSC amplitudes vary in a quantal fashion. The quantal size varied between 7 and 20 pA, at a membrane potential of ‐50 mV. 6. Decreasing the Ca2+ and increasing the Mg2+ concentration in the extracellular solution decreased the number of peaks in the IPSC amplitude histogram but did not affect the size of the quantal event. (ABSTRACT TRUNCATED AT 400 WORDS)
Psycho-visual quality assessment of state-of-the-art denoising schemes

In this paper we compare the quality of 7 state-of-the-art denoising schemes based on human visual perception. 3 of those are wavelet-based filter schemes, 1 is Discrete Cosine Transform-based, 1 is Discrete Fourier Transform-based, 2 are Steerable Pyramid-based and 1 is Fuzzy Logic based. A psycho-visual experiment was set up in which 37 subjects were asked to score and compare denoised images coming from 3 different scenes. A Multi-Dimensional Scaling framework was then used to process the data of this experiment. This lead to a ranking of the filters in perceived overall image quality. In a follow-up experiment other attributes such as the noisiness, bluriness and artefacts present in the denoised images allowed us also to determine why people choose one filter over the other.
Intradermal Vaccination with Influenza Virus-Like Particles by Using Microneedles Induces Protection Superior to That with Intramuscular Immunization

ABSTRACT Influenza virus-like particles (VLPs) are a promising cell culture-based vaccine, and the skin is considered an attractive immunization site. In this study, we examined the immunogenicity and protective efficacy of influenza VLPs (H1N1 A/PR/8/34) after skin vaccination using vaccine dried on solid microneedle arrays. Coating of microneedles with influenza VLPs using an unstabilized formulation was found to decrease hemagglutinin (HA) activity, whereas inclusion of trehalose disaccharide preserved the HA activity of influenza VLP vaccines after microneedles were coated. Microneedle vaccination of mice in the skin with a single dose of stabilized influenza VLPs induced 100% protection against challenge infection with a high lethal dose. In contrast, unstabilized influenza VLPs, as well as intramuscularly injected vaccines, provided inferior immunity and only partial protection (≤40%). The stabilized microneedle vaccination group showed IgG2a levels that were 1 order of magnitude higher than those of other groups and had the lowest lung viral titers after challenge. Also, levels of recall immune responses, including hemagglutination inhibition titers, neutralizing antibodies, and antibody-secreting plasma cells, were significantly higher after skin vaccination with stabilized formulations. Therefore, our results indicate that HA stabilization, combined with vaccination via the skin using a vaccine formulated as a solid microneedle patch, confers protection superior to that with intramuscular injection and enables potential dose-sparing effects which are reflected by pronounced increases in rapid recall immune responses against influenza virus.
A method for combining United States and Canadian bull evaluations.

Canadian and US genetic evaluations for July 1991 were combined for 3304 Holstein bulls evaluated in Canada that had US progeny or a cross-reference code. Canadian evaluations of the bulls and their sires and dams were converted to US PTA. Combined PTA were weighted averages of progeny information from both countries and parent average. Parent average was recomputed from the sire's combined evaluation and the dam's evaluation with the most daughter equivalents. Bulls were processed in birth year order so that combined evaluation of sire was available. Progeny contribution was adjusted to remove the influence of the bull's evaluation on progeny evaluations through their parent averages, which left only the portion that was due to progeny records and grandprogeny information. A weighted average of adjusted progeny contributions was combined with parent average to form a combined PTA more accurately than possible by averaging domestic and converted PTA. Combined reliability was computed by summing daughter equivalents from progeny and from updated evaluations of parents. Canadian daughter equivalents were multiplied by . 9 to approximate US values. Combined evaluations simplify bull selection by providing comparable and complete information for bulls evaluated in two countries.