Miracle-dz/UniFAR-FTUs huggingface dataset:
Risk assessment of offshore platform due to ship collision

Offshore platforms work in complex and harsh environments, in addition to normal work load, environment loads, also threatened by accidental loads, such as the impact of ships. Major disaster caused by accidental loading will not only result in casualties and major economic losses, but also the surrounding coastal environment and marine ecosystem caused by pollution and destruction So it is essential to analyze and assess the behaviors of platform subjected to the accidental loading. The work presented in this paper focus on the risk of ship collision. On the basis of research on the risk analysis method and structural collision damage, offshore platform collision risk quantitative assessment system is built to achieve the risk assessment of offshore platforms from the traditional experience to scientific prediction type.
06431 Working Group Report on Managing and Integrating Data in P2P Databases

In this report, to our best recollection, we provide a summary of the working group A¢â‚¬EœManaging and Integrating Data in P2P DatabasesA¢â‚¬â„¢ of the Dagstuhl Seminar nr. 6431 on A¢â‚¬EœScalable Data Management in Evolving NeworksA¢â‚¬â„¢, held on October 23-27 in Dagstuhl (Germany).
Variable empirical coefficient algorithm for removal of topographic effects on remotely sensed data from rugged terrain

A new topographic correction approach, Variable Empirical Coefficient Algorithm (VECA), was developed on the theoretical and statistic analysis of the spectral response of remotely sensed data acquired from the rugged terrain and topographic variables. Practical performance of the proposed approach was systematically introduced and analyzed in comparison with that before topographic correction. The test site selected for the study is located on the relatively rugged terrain over the south hill of the Qinling Mountain in Shanxi province, China, the remotely sensed data utilized for examining the performance of the proposed approach VECA is Landsat-7 ETM+ image acquired over the test site. Visual comparison and statistical analysis were adopted for feasible evaluation of the proposed algorithm, and the results suggested that the proposed approach VECA is capable for removing the topographic effects contained in ETM+ image, VECA was not only good in performance on topographical affection removal but also simple in theory and easy for operation, which implied the VECA an effective topographic correction algorithm in remote sensing techniques.
Safety of Back‐Transfer to Local Hospitals During an Acute Care Hospitalization

PURPOSE This paper investigates patient outcomes including length of stay (LOS), cost of hospitalization, bounce-back rates, transition to hospice care, and mortality, following back-transfer. METHODS This study was an observational case-control study of adults hospitalized in Iowa between 2005 and 2013 to identify back-transferred patients. Back-transfer was defined as the transfer of rural patients near the end of their acute hospitalization in a comprehensive medical center back to a local community hospital for the completion of their medical care. Demographic, geographic, rurality, procedural, and disease information was compared between case and control groups, then propensity score (PS) matching was performed to create comparable groups to perform analyses. FINDINGS Over the 9-year period, 1,056,773 patients meeting inclusion criteria were admitted, of which 430 (0.04%) were back-transferred. After PS matching, LOS was 60% (95% CI: 0.50-0.71) higher and costs were 42% (95% CI: 0.33-0.50) higher in the back-transferred group. Back-transferred cases had 8.34 (95% CI: 3.66-19.0) times the odds of hospice transition and 2.17 (95% CI: 1.37-3.46) the odds of mortality compared to controls. Four percent of back-transfers "failed" with the patient being returned to the larger hospital before discharge. CONCLUSIONS Back-transfer is a rare occurrence, and it is associated with longer LOS, higher hospitalization cost, higher mortality, more hospice transfers, and occasional bounce-backs to comprehensive medical centers. Future work should focus more on prospective indications for transfer, the role of end-of-life care, financial impact, and identifying patient populations for whom back-transfer is safest.
Research on Adoption of Mobile Virtual Community in China and Korea

Due to the widespread development of mobile internet, more and more users will transfer to mobile virtual community from web community. This study attempts to understand factors affecting the adoption of mobile virtual community in addition to those affecting other mobile services. An adoption model that reflects the characteristics of mobile virtual community is developed. The model consists of the factors in virtual community and common mobile services and is tested both in China and Korea. Our findings show that perceived cost, perceived ease of use and social influence will affect intention to use significantly. Social capital and trust are crucial factors affecting perceived usefulness in mobile virtual community. We also find that the adoption patterns in China and Korea have great differences. In Korea adopters put more weight on perceived cost, perceived ease of use and perceived similarity, while in China adopters put more weight on perceived playfulness and familiarity.
Tyrosine hydroxylase‐expressing and/or aromatic L‐amino acid decarboxylase‐expressing neurons in the mediobasal hypothalamus of perinatal rats: Differentiation and sexual dimorphism

In this quantitative and semiquantitative immunocytochemical study, the authors evaluated the differentiation of neurons expressing tyrosine hydroxylase (TH) and/or aromatic L‐amino acid decarboxylase (AADC) in the mediobasal hypothalamus (MBH) of male and female rats on embryonic day 18 ( E18 ), E20, and postnatal day 9 ( P9 ). Four neuronal populations were distinguished according to either enzyme expression or neuron location. The earliest and most prominent first population was represented by TH‐immunoreactive (IR)/AADC‐immunonegative (IN) neurons that were detected initially at E18 and always were located in the ventrolateral region of the MBH. The second population of TH‐IN/AADC‐IR neurons was observed first at E20 and, after that time, was distributed dorsomedially. The third minor population of TH‐IR/AADC‐IR neurons initially was detected at E20 and was located dorsomedially. The fourth population was represented by TH‐IR/AADC‐IN neurons that were distributed in the dorsomedial region at any studied age. The numbers of TH‐IR and AADC‐IR neurons increased from their initial detection at E18 and E20 until P9. The area of TH‐IR and AADC‐IR neurons also increased from E18 to E20 and from E20 to P9, respectively. Both TH‐IR and AADC‐IR neurons showed sex differences in the neuron number, size, and optic density (OD). The numbers of TH‐IR neurons in males exceeded those of females at E20 and at P9, although, at P9, sexual dimorphism was a characteristic only of the ventrolateral population. The area and OD of TH‐IR neurons from females exceeded those from males in the entire mediobasal hypothalamus (MBH) at E18 and E20 but only in its dorsomedial region at P9. Sexual dimorphism also was an attribute of AADC‐IR neurons at E20 and P9. Their number, size, and OD were significantly higher in females than in males. Thus, the MBH of perinatal rats contained two major populations of TH‐IR/AADC‐IN or TH‐IN‐AADC‐IR neurons and a minor population of TH‐IR/AADC‐IR neurons. The differentiating neurons expressing either enzyme showed sexual dimorphism. J. Comp. Neurol. 425:167–176, 2000. © 2000 Wiley‐Liss, Inc.
Behavior description algorithm based on home sensor data using nonlinear transformations

This paper presents a behavior description algorithm from time-series data on daily life activities extracted using home sensors. In a previous work, we proposed a method of time-series data clustering based on hidden Markov models (HMMs). This method separates the time-series data in segments of equally short length, and applies a behavior label for each segment. However, the change points of behaviors are not clear and it is difficult to detect short length behavior. In this paper, we propose a new behavior description algorithm by introducing singular spectrum transformation (SST), a nonlinear transformation used for change-point detection, and apply it to our previous method. This method enables more precise change-point detection and behavior labeling.
A novel three-dimensional hybrid spatial model for wideband MIMO channel in indoor environments

Studies of the effects of three-dimensional (3D) propagations on MEMO channel correlation and capacity have been presented in some literatures based on given 3D stochastic models of angle spectrum. However, it is only for narrowband MEVIO channels and can not properly include specular reflections due to walls and/or the ground. In this letter, a hybrid spatial channel model, which combines a 3D ray-tracing based model for deterministic rays with a new 3D model for single-bounce randomly scattering rays, is proposed to investigate wideband spatial/polarized MEVIO channel correlation. Based on the proposed model, the per-tap correlation among MEVIO subchannels is formulated and is validated by indoor measurements. From the comparison between measured and computed subchannel correlations, it is found that our 3D model is more accurate than the 2D model, which only considers the propagation path in the horizontal plane, for both the co-polarized and the cross-polarized antenna cases. It is noted that the concept of effective scattering region is introduced in our model, which can increase computation efficiency without sacrifice the prediction accuracy.
Evaluation of a Novel Therapeutic Repetitive Transcranial Magnetic Stimulation Technique Optimized for Increased Accessibility in Major Depression

ABSTRACT BACKGROUND Repetitive transcranial magnetic stimulation (rTMS) is effective in major depressive disorder (MDD). However, technical complexity and operational costs might have been barriers for its wide use and implementation in some jurisdictions, thereby decreasing accessibility. OBJECTIVE Our main goal was to test the feasibility of a novel rTMS protocol optimized for practicality, scalability and cost-effectiveness. We hypothesized that our novel rTMS protocol would be simple to implement and well-tolerated, but less costly and allow for more treatment capacity. METHODS Treatment was administered in an open-room setting, allowing a single technician to attend to multiple patients. Large non-focal parabolic coils held by custom-built arms allowed simple yet efficient and accurate placement. We employed a low-frequency (LF) 1 Hz stimulation protocol (360 pulses per session), delivered on the most affordable FDA-approved devices. MDD participants received an initial accelerated rTMS course (arTMS) of 6 sessions/day over 5 days (30 total), followed by a tapering course of daily sessions (up to 25) to decrease the odds of relapse. The self-reported Beck Depression Inventory II (BDI-II) was used to measure severity of depression. RESULTS Forty-eight (48) patients completed the arTMS course. No serious adverse events occurred, and all patients reported manageable pain levels. Response and remission rates were 35.4% and 27.1% on the BDI-II, respectively, at the end of the tapering course. CONCLUSION If rTMS could be delivered for lower cost at higher volume, while preserving efficacy, safety and tolerability, it could warrant further investigation of this treatment as a first-line intervention in MDD. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT04376697
The Safety Property of β-D-Mannuronic Acid (M2000) as a Novel Immunosuppressive Agent on Differentiation, Maturation and Function of Human Dendritic Cells.

The study's background and aim: In this investigation, the safety property of M2000 (β-D-mannuronic acid) on differentiation, maturation and function of dendritic cells, was determined. β-D-mannuronic acid, as a novel immunosuppressive and anti-inflammatory agent, has been tested in various experimental models. In addition, DC-based immunosuppressive drugs can suppress the progression of autoimmune diseases, although, their notable side effects in increasing the risk of infectious diseases and cancers should be considered. MATERIALS AND METHODS The effect of M2000 on differentiation, maturation and function of dendritic cells was examined. To investigate how M2000 affects human dendritic cells (DC) in a defined inflammatory environment, human peripheral blood mononuclear cells (PBMC) were isolated from healthy blood and monocytes were purified using anti-CD14 microbeads. Monocytes were incubated with M2000 in two different doses (6 and 12 J.g/well) along with adding the granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-4 for inducing monocytes to immature DC and lipopolysaccharide for running DC maturation. The differentiation, maturation and function of dendritic cells were examined with flow cytometry and ELISA method. RESULT The results demonstrate that M2000 has no significant side on differentiation, maturation and function of dendritic cells in immature DC and mature DC process in vitro. CONCLUSION Our findings show that β-D-mannuronic acid (m2000) as a safe agent had no adverse effect on differentiation, maturation and function of dendritic cells which might be recommended as a novel immunosuppressive agent with no or fewer side effects in increasing the risk of infectious diseases and cancers.
Vacuum clefts of the vertebral bodies.

BACKGROUND AND PURPOSE The appearance of vacuum clefts (VCs) of the vertebral bodies has frequently been considered pathognomonic for avascular necrosis. Until recently, this was considered to be a rare finding that might indicate excessive motion at the fracture site. Our aim in this retrospective study was to determine the occurrence and location of these clefts in patients with osteoporotic vertebral fractures and evaluate the risk factors involved for developing these clefts in such patients. METHODS The records of 66 patients with 101 painful osteoporotic vertebral fractures who were treated by vertebroplasty in our department were reviewed. All the fractures with VCs were collected. Age, sex, degree of deformity, and extent of degenerative changes in the adjacent disk space were compared with those found in the patients without clefts. RESULTS VCs were found in 26 fractured vertebrae of 26 patients. They were significantly more common in elderly men who had deformed fractures located at the thoracolumbar junction, when compared with fractures without clefts, especially when degenerative changes were observed in the adjacent disk space. CONCLUSION This study suggests that VCs, which have long been considered pathognomonic for avascular necrosis (Kümmell disease), are not rare and most probably represent fracture nonunion. Elderly patients who have deformed fractures at the thoracolumbar area have a higher risk for developing clefts, mainly when there is degeneration of the adjacent disk space.
RP-HPLC-DAD-ESI-QTOF-MS based metabolic profiling of the potential Olea europaea by-product "wood" and its comparison with leaf counterpart.

INTRODUCTION Olea europaea L. organs such as leaves, stems and roots have been associated with numerous in vivo and in vitro biological activities and used for traditional medicinal purposes. However, tree wood is an untapped resource with little information about their chemical composition. OBJECTIVE That is why, the objective of this study is to increase the knowledge about phytochemicals from 'Chemlali' olive wood by means of mass spectrometry-based analyses. Its comparison with by-products derived from leaves was also studied. METHODOLOGY Hydromethanol extracts from wood and leaves with stems of 'Chemlali' olive cultivar were analysed using reversed-phase (RP) high-performance liquid chromatography (HPLC) coupled to two detection systems: diode-array detection (DAD) and quadrupole time-of-flight (QTOF) mass spectrometry (MS) in negative ion mode. Tandem MS experiments were performed to establish the chemical structure of olive phytochemicals. RESULTS A total of 85 compounds were characterised in the studied olive parts and classified as: sugars (3), organic acids (5), one phenolic aldehyde, simple phenolic acids (6), simple phenylethanoids (5), flavonoids (14), coumarins (3), caffeoyl phenylethanoid derivatives (6), iridoids (5), secoiridoids (32), and lignans (5). To our knowledge, the major part of these metabolites was not previously reported in olive tree wood, and 10 olive chemical constituents were identified for the first time in the Oleaceae family. CONCLUSION The results presented here demonstrated the usefulness of the methodology proposed, based on RP-HPLC-DAD-ESI-QTOF-MS and MS/MS, to develop an exhaustive metabolic profiling and to recover new biologically active compounds in olive wood with pharmacologic and cosmetic potential. Copyright © 2017 John Wiley & Sons, Ltd.
Laparoscopic Liver Resections: A Feasibility Study in 30 Patients

ObjectiveTo assess the feasibility and safety of laparoscopic liver resections. Summary Background DataThe use of the laparoscopic approach for liver resections has remained limited for technical reasons. Progress in laparoscopic procedures and the development of dedicated technology have made it possible to consider laparoscopic resection in selected patients. MethodsA prospective study of laparoscopic liver resections was undertaken in patients with preoperative diagnoses including benign lesion, hepatocellular carcinoma with compensated cirrhosis, and metastasis of noncolorectal origin. Hepatic involvement had to be limited and located in the left or peripheral right segments (segments 2–6), and the tumor had to be 5 cm or smaller. Surgical technique included CO2 pneumoperitoneum and liver transection with a harmonic scalpel, with or without portal triad clamping or hepatic vein control. Portal pedicles and large hepatic veins were stapled. Resected specimens were placed in a bag and removed through a separate incision, without fragmentation. ResultsFrom May 1996 to December 1999, 30 of 159 (19%) liver resections were included. There were 18 benign lesions and 12 malignant tumors, including 8 hepatocellular carcinomas in cirrhotic patients. Mean tumor size was 4.25 cm. There were two conversions to laparotomy (6.6%). The resections included 1 left hepatectomy, 8 bisegmentectomies (2 and 3), 9 segmentectomies, and 11 atypical resections. Mean blood loss was 300 mL. Mean surgical time was 214 minutes. There were no deaths. Complications occurred in six patients (20%). Only one cirrhotic patient developed postoperative ascites. No port-site metastases were observed in patients with malignant disease. ConclusionLaparoscopic resections are feasible and safe in selected patients with left-sided and right-peripheral lesions requiring limited resection. Young patients with benign disease clearly benefit from avoiding a major abdominal incision, and cirrhotic patients may have a reduced complication rate.
Sailing and Sailing Rigs in the Ancient Mediterranean: implications of continuity, variation and change in propulsion technology

Abstract Ships and boats form the foundations of the maritime connectivity that is a central part of our understanding of the ancient Mediterranean. While the general chronological sequence of sail and sailing‐rig development is well established, the implications are less‐well discussed. This article sets out how sails and sailing rigs developed in antiquity, with emphasis on the Greco‐Roman world. Subsequently, instances of innovation are defined. Why specific pieces of maritime technology were, or were not, widely adopted is considered. Long‐term technological continuity can be comprehended, and a shared maritime culture of sailing in the ancient Mediterranean is suggested. 抽象 古代地中海的帆与索具:推进技术连贯性、演变与变化的影响 船舶是构成海上连通的基础, 而海上连通则是我们了解古代地中海的核心组成部分。 虽然帆与索具发展的基本序列已很好地建立起来, 但其影响却很少被-论。 本文以希腊罗马世界为重点, 首先探讨帆与索具在古代的发展演进。 随后, 我们界定出具体的变革实例。 在文中我们还会-论特定的航海技术部件为何-被广泛使用或抛弃的问题。 我们-识到技术具有长期连续性, 并提出古代地中海存在一种风帆共享的航海文化这-观点。 关键词:地中海, 帆, 航海, 横帆, 斜杠帆, 三角帆 古代地中海的帆與索具:推進技術-貫性、演變-變化的影響 船舶是構成海上連通的基礎, 而海上連通則是我們了解古代地中海的核心組成部分。 雖然帆與索具發展的基本序列已很好地建立起來, 但其影響卻很少被-論。 本文以希臘羅馬世界爲重點, 首先探討帆與索具在古代的發展演進。 隨後, 我們界定出具體的變革實例。 在文中我們還會討論特定的航海技術-件爲何會被廣泛使用或抛棄的問題。 我們-識到技術具有長期連續性, 並提出古代地中海存在一種風帆共享的航海文化這一-點。 關-詞:地中海, 帆, 航海, 橫帆, 斜杠帆, 三角帆
Do Immediate Cytology and Specialist Radiologists Improve the Adequacy of Ultrasound-Guided Fine-Needle Aspiration Cytology?

Objective To assess whether a dedicated “1-stop” neck lump clinic has improved the percentage of adequate fine-needle aspiration cytology (FNAC) samples and reduced the need for repeat FNAC. Study Design Retrospective review. Setting District General Hospital in the United Kingdom. Subjects and Methods Patients attending for ultrasound-guided FNAC over a 6-month period from August 2012 to February 2013. Patients were placed in 4 groups: group 1, FNAC performed by any of the subspecialist radiologists with cytology support (n = 100); group 2, FNAC performed by general radiologists without cytology support (n = 112); group 3, FNAC performed by a particular subspecialist radiologist with cytology support (n = 61); and group 4, FNAC performed by the same subspecialist radiologist without cytology support (n = 125). Results There was a significantly higher rate of adequacy of FNAC in the presence of a subspecialist radiologist with immediate cytology (group 1) versus a general radiologist without cytology support (group 2; 87/100 vs 63/112, P = .0001), a significantly higher rate of adequacy of FNAC in the presence of cytology support with the same radiologist (group 3 vs group 4, 55/61 vs 97/125, P = .04), and a significantly higher rate of adequacy of FNAC in the presence of a subspecialist radiologist versus a general radiologist without cytology support (group 4 vs group 2, 97/125 vs 63/112, P = .0005). Conclusion Immediate cytology and the presence of a subspecialist radiologist increase the adequacy of FNAC. The adequacy rate of non–cytology-supported FNAC or nonsubspecialist FNAC is below the adequate rate expected from the literature or as recommended in national guidelines.
PrPC regulates epidermal growth factor receptor function and cell shape dynamics in Neuro2a cells

The prion protein (PrP) plays a key role in prion disease pathogenesis. Although the misfolded and pathologic variant of this protein (PrPSC) has been studied in depth, the physiological role of PrPC remains elusive and controversial. PrPC is a cell‐surface glycoprotein involved in multiple cellular functions at the plasma membrane, where it interacts with a myriad of partners and regulates several intracellular signal transduction cascades. However, little is known about the gene expression changes modulated by PrPC in animals and in cellular models. In this article, we present PrPC‐dependent gene expression signature in N2a cells and its implication in the most overrepresented functions: cell cycle, cell growth and proliferation, and maintenance of cell shape. PrPC over‐expression enhances cell proliferation and cell cycle re‐entrance after serum stimulation, while PrPC silencing slows down cell cycle progression. In addition, MAP kinase and protein kinase B (AKT) pathway activation are under the regulation of PrPC in asynchronous cells and following mitogenic stimulation. These effects are due in part to the modulation of epidermal growth factor receptor (EGFR) by PrPC in the plasma membrane, where the two proteins interact in a multimeric complex. We also describe how PrPC over‐expression modulates filopodia formation by Rho GTPase regulation mainly in an AKT‐Cdc42‐N‐WASP‐dependent pathway.