Miracle-dz/UniFAR-FTUs huggingface dataset:
Transforming the JSON Output of SPARQL Queries for Linked Data Clients

SPARQL endpoints are one possible access method to linked data. The results of SPARQL queries serialized in JSON are, however, not suitable to be directly used by web developers in end-user applications who often need to merge the values resulting from variable bindings. In this work, we propose a generic approach implemented in a JavaScript module that takes as input a JSON file describing both the SPARQL query and the shape of the expected output at the same time.
Diversity , Internal Environment , Shared Leadership , and Information Sharing in Short-Duration Virtual Teams : Findings from a Laboratory Experiment

The purpose of this research is to examine the relationships among diversity, internal environment, shared leadership, and information sharing of short-duration virtual teams engaged in a problem solving task. A laboratory experiment was conducted involving collaboration technology supported virtual teams that were engaged in a task on conceptual data model design. Two forms of team diversity were measured e.g. national cultural and education specialization diversities. We found that educational specialization diversity adversely affected internal environment which in its turn, had a positive relationship with shared leadership in the teams. We also found that shared leadership was positively related to information sharing in the virtual teams.
SURGICAL EXPERTS - BORN OR MADE?

Expertise in surgery needs to be cultivated in order to increase patient safety and improve practice. Expert practice consistently produces outcomes that are consistently superior to that of professional peers(Anon 2010;Ericsson et al. 2007). ‘Experienced non-experts’ (Mylopoulos and Regehr 2007) are individuals competent in performing familiar tasks, out-performing non specialists, yet being unable to surpass their level of practice or adapt to new scenarios. These are known as ‘routine experts’ and must differentiated from ‘adaptive experts’ who seek new challenges and “explore and expand their current level of expertise (Bransford JD et al. 2000;Mylopoulos & Regehr 2007). Medical expertise canmanifestedas improved patient outcomes, expressed in terms of mortality, morbidity, disease-free survival and quality of life. Cognitive capacity, long-term memory and problem-solvingability are intrinsic aspects of medical expertise, manifested through superior diagnostic capacity. Surgical expertise however requires superior performance in additional domains, such asresponsible risk-taking behaviour, visual-spatial orientation and psychomotor ability,expressed as difficult decision-making capacity, economy of movement and automaticity(Schaverien 2010). In order to determine whether expert surgeons are born or made, it is important to identify whether the characteristic features of surgical expertise arise through practice and training or whether they depend on intrinsic ability, specific personality types and circumstances in which individuals are born. ARE SURGICAL EXPERTS ARE BORN?
Chopper Stabilized, Low-Power, Low-Noise, Front End Interface Circuit for Capacitive CMOS MEMS Sensor Applications

In this paper, a chopper stabilized fully differential CMOS pre-amplifier circuit is presented. The proposed circuit is designed for sub-atto Farad capacitive CMOS MEMS sensing applications. Chopper stabilization technique is employed to minimize flicker (1/f) noise and offsets in the circuit. The proposed circuit is designed using MIMOS 0.35 μm AMS CMOS 3.3 V technology and simulation results from Cadence Virtuoso Spectre circuit simulator show that the proposed circuit is able to detect capacitance changes ranging from 0.0375 aF to 37.5 fF, attain an input inferred noise of 0.9 nV/√Hz, gain of 18.1 dB at 3-dB frequency of 5.5 MHz with total power consumption of 0.33 mW.
The impact of the food-based and nutrient-based standards on lunchtime food and drink provision and consumption in primary schools in England

Abstract Objective To assess lunchtime provision of food and drink in English primary schools and to assess both choices and consumption of food and drink by pupils having school lunches. These findings were compared with similar data collected in 2005. Design Cross-sectional data collected between February and April 2009. In each school, food and drink provision, including portion weights and number of portions of each item served at lunchtime, were recorded over five consecutive days. Caterers provided school lunchtime menus and recipes. Setting England. Subjects A random selection of 6696 pupils having school lunches in a nationally representative sample of 136 primary schools in England. Results Compared with 2005, schools in 2009 provided significantly more fruit, fruit-based desserts, vegetables and salad, water and fruit juice, and less ketchup, sauces and gravy, starchy foods cooked in fat, snacks and confectionery (P < 0·01). Pupils were also making healthier choices, choosing an average of 2·2 portions of fruit and vegetables from their ‘five a day’, but about one-third to two-fifths of these were wasted. Conclusions Lunchtime food provision and consumption in primary schools have improved substantially since 2005, following the introduction of new standards for school food in 2008. However, improvements still need to be made to increase the Fe and Zn content and to decrease the Na content of recipes, and in encouraging pupils to eat more of the fruits and vegetables taken at lunchtime.
Cooperation between search and surveillance agents in DCOP MST

A team of mobile sensors working together towards a common goal of covering targets in some area, can be modeled by DCOP MST. DCOP MST, is a model based on distributed constraints optimization that enables representation of the dynamic elements in a mobile sensing agents team problem, e.g., environment changes, changes in the agents’ tasks and technology failures. Agents in DCOP MST, perform local DCOP algorithms, adjusted to this model, in order to adjust their deployment to the current state of the dynamic environment. In our previous work on DCOP MST we assumed complete and accurate knowledge on the location and importance of targets in the area. This information might not be available in realistic scenarios. In this paper we consider two teams of agents, (a) sensors with advanced mobility and sensing tasked to detect targets, and (b) sensors with limited mobility tasked with target surveillance. We demonstrate how the DCOP MST model can be used by these two teams to fulfill their sub-tasks, and how it can be used for cooperation among the two teams. Our experimental study demonstrates how an increased level of cooperation among the two teams improves the performance of both teams and improves the overall result on fulfilling the mutual coverage goal.
Ethnic differences in common carotid intima-media thickness, and the relationship to cardiovascular risk factors and peripheral arterial disease: the Ethnic-Echocardiographic Heart of England Screening Study.

OBJECTIVE To compare the mean and maximum common carotid intima-media thickness (CCIMT) in Blacks (Black Caribbean and Black African) and South Asians (People originating from India, Pakistan and Bangladesh) in a population survey and make associations with established cardiovascular risk factors and peripheral arterial disease (PAD). PATIENTS AND METHODS A subset of 492 (293 South Asians and 199 Blacks) out of 572 participants aged ≥ 45 years recruited in a sub-study to the Ethnic-Echocardiographic Heart of England Screening (E-ECHOES) epidemiological study had mean and maximum CCIMT measured. A questionnaire, anthropometric measurements and Ankle Brachial Pressure Index (ABPI) and Intermittent Claudication assessments were made. RESULTS Black participants had greater mean but not maximum CCIMT when compared to South Asians overall (P = 0.022), in men (P = 0.04) and in women (P = 0.044). Black ethnicity was an independent predictor of CCIMT even after adjustment for traditional cardiovascular risk factors (P < 0.05). After adjustment for age, ethnicity and traditional cardiovascular risk factors, the presence of PAD remained independently predictive of mean (P = 0.019) and maximum (P = 0.012) CCIMT. CONCLUSION Black ethnicity is related to greater mean and maximum CCIMT when compared to South Asians, even after adjusting for traditional cardiovascular risk factors. The presence of PAD independently predicts mean and maximum CCIMT adjusting for ethnicity, age and cardiovascular risk factors.
Multiple drawing multi-colour urns by stochastic approximation

Abstract A classical Pólya urn scheme is a Markov process where the evolution is encoded by a replacement matrix (Ri, j)1 ≤ i, j ≤ d. At every discrete time-step, we draw a ball uniformly at random, denote its colour c, and replace it in the urn together with Rc, j balls of colour j (for all 1 ≤ j ≤ d). We study multiple drawing Pólya urns, where the replacement rule depends on the random drawing of a set of m balls from the urn (with or without replacement). Many particular examples of this situation have been studied in the literature, but the only general results are due to Kuba and Mahmoud (2017). These authors proved second-order asymptotic results in the two-colour case, under the so-called balance and affinity assumptions, the latter being somewhat artificial. The main idea of this work is to apply stochastic approximation methods to this problem, which enables us to prove analogous results to Kuba and Mahmoud, but without the artificial affinity hypothesis, and, for the first time in the literature, in the d-colour case (d ≥ 3). We also provide some partial results in the two-colour nonbalanced case, the novelty here being that the only results for this case currently in the literature are for particular examples.
Linking Social Networks on the Web with FOAF: A Semantic Web Case Study

One of the core goals of the Semantic Web is to store data in distributed locations, and use ontologies and reasoning to aggregate it. Social networking is a large movement on the web, and social networking data using the Friend of a Friend (FOAF) vocabulary makes up a significant portion of all data on the Semantic Web. Many traditional web-based social networks share their members' information in FOAF format. While this is by far the largest source of FOAF online, there is no information about whether the social network models from each network overlap to create a larger unified social network, or whether they are simply isolated components. If there are intersections, it is evidence that Semantic Web representations and technologies are being used to create interesting, useful data models. In this paper, we present a study of the intersection of FOAF data found in many online social networks. Using the semantics of the FOAF ontology and applying Semantic Web reasoning techniques, we show that a significant percentage of profiles can be merged from multiple networks. We present results on how this affects network structure and what it says about the success of the Semantic Web.
Automatic Transfer Functions Based on Informational Divergence

In this paper we present a framework to define transfer functions from a target distribution provided by the user. A target distribution can reflect the data importance, or highly relevant data value interval, or spatial segmentation. Our approach is based on a communication channel between a set of viewpoints and a set of bins of a volume data set, and it supports 1D as well as 2D transfer functions including the gradient information. The transfer functions are obtained by minimizing the informational divergence or Kullback-Leibler distance between the visibility distribution captured by the viewpoints and a target distribution selected by the user. The use of the derivative of the informational divergence allows for a fast optimization process. Different target distributions for 1D and 2D transfer functions are analyzed together with importance-driven and view-based techniques.
Comparison of 2 mapping strategies for pulmonary vein isolation.

BACKGROUND Pulmonary vein (PV) isolation using a circular catheter (CC) creates an entrance block from the left atrium (LA) to PV to eliminate paroxysmal atrial fibrillation (PAF). We describe a new approach for PV isolation during distal PV pacing using a basket catheter (BC). The purpose of the present study was to compare 2 mapping strategies for PV isolation. METHODS AND RESULTS Of 100 consecutive patients with PAF, 50 underwent CC-guided PV isolation and 50 underwent BC-guided PV isolation. During CC-guided ablation, the endpoint was the elimination of PV potentials based on the entrance block from the LA to PV. During BC-guided ablation during distal PV pacing, the endpoint was the elimination of bidirectional PV-LA conduction. At 12 months, 62% of patients who underwent CC ablation and 80% of patients who underwent BC ablation were free of symptomatic PAF without the use of antiarrhythmic drugs (p<0.05). The incidence of mild (<50%) PV stenosis in BC ablation was significantly lower than that in CC ablation (12 vs 24%, p<0.01). CONCLUSIONS This new approach for PV isolation during distal PV pacing using BC is useful for confirming a bidirectional PV-LA conduction block and is more effective than CC ablation.
On the assessment of tree-based and chance-constrained predictive control approaches applied to drinking water networks

Abstract Water systems are a challenging problem because of their size and exposure to uncertain influences such as the unknown demands or the meteorological phenomena. In this paper, two different stochastic programming approaches are assessed when controlling a drinking water network: chance-constrained model predictive control (CC-MPC) and tree-based model predictive control (TB-MPC). Under the former approach, the disturbances are modelled as stochastic variables with non-stationary uncertainty description, unbounded support and quasi-concave probabilistic distribution. A deterministic equivalent of the related stochastic problem is formulated using Boole's inequality and a uniform allocation of risk. In the latter approach, water demand is modelled as a disturbance rooted tree where branches are formed by the most probable evolutions of the demand. In both approaches, a model predictive controller is used to optimise the expectation of the operational cost of the disturbed system.
Restricted Cell Surface Expression of Receptor Tyrosine Kinase ROR1 in Pediatric B-Lineage Acute Lymphoblastic Leukemia Suggests Targetability with Therapeutic Monoclonal Antibodies

Background Despite high cure rates for pediatric B-lineage acute lymphoblastic leukemia (B-ALL), short-term and long-term toxicities and chemoresistance are shortcomings of standard chemotherapy. Immunotherapy and chemoimmunotherapy based on monoclonal antibodies (mAbs) that target cell surface antigens with restricted expression in pediatric B-ALL may offer the potential to reduce toxicities and prevent or overcome chemoresistance. The receptor tyrosine kinase ROR1 has emerged as a candidate for mAb targeting in select B-cell malignancies. Methodology and Principal Findings Using flow cytometry, Western blotting, immunohistochemistry, and confocal immunofluorescence microscopy, we analyzed the cell surface expression of ROR1 across major pediatric ALL subtypes represented by 14 cell lines and 56 primary blasts at diagnosis or relapse as well as in normal adult and pediatric tissues. Cell surface ROR1 expression was found in 45% of pediatric ALL patients, all of which were B-ALL, and was not limited to any particular genotype. All cell lines and primary blasts with E2A-PBX1 translocation and a portion of patients with other high risk genotypes, such as MLL rearrangement, expressed cell surface ROR1. Importantly, cell surface ROR1 expression was found in many of the pediatric B-ALL patients with multiply relapsed and refractory disease and normal karyotype or low risk cytogenetics, such as hyperdiploidy. Notably, cell surface ROR1 was virtually absent in normal adult and pediatric tissues. Conclusions and Significance Collectively, this study suggests that ROR1 merits preclinical and clinical investigations as a novel target for mAb-based therapies in pediatric B-ALL. We propose cell surface expression of ROR1 detected by flow cytometry as primary inclusion criterion for pediatric B-ALL patients in future clinical trials of ROR1-targeted therapies.
Base excision repair ( BER ) of 7 , 8-dihydro-8-oxoguanine ( 8-oxoG ) in DNA mismatch repair proficient and mismatch repair deficient human cells

Oxidative damage is one of the most common types of DNA damage and is considered a key factor in carcinogenesis. A major form of oxidative DNA lesion is 7, 8-dihydro-8oxoguanine (8-oxoG). The plasmid p220-12-8-oxoG:A containing the 8-oxoG located on the H-Ras codon 12 was either used to directly transform DH5α and NR12397 competent cells or after the plasmid had been incubated with HeLa, DLD1, and HCT 116 nuclear extracts. The repair efficiency of different cell lines was assessed. We also demonstrated that 40 mer Ras 8-oxoG located on H-Ras codon 12 opposite to A or C incubated with HeLa, DLD1, HCT116+3, HCT116 and LoVo nuclear extracts in BER nicking assay showed cell incision ability that uncorrelated with the levels of hMYH expression in different cell lines. We propose that the 8-oxoG:A DNA lesion located on the H-Ras codon 12 is difficult to be repaired, and that the MMR protein hMutSα may interfere with the 8-oxoG:A BER repair at codon 12. And hMutLα may contribute to the MYH in BER.
Bacterial transmembrane signalling systems and their engineering for biosensing

Every living cell possesses numerous transmembrane signalling systems that receive chemical and physical stimuli from the environment and transduce this information into an intracellular signal that triggers some form of cellular response. As unicellular organisms, bacteria require these systems for survival in rapidly changing environments. The receptors themselves act as ‘sensory organs’, while subsequent signalling circuits can be regarded as forming a ‘neural network’ that is involved in decision making, adaptation and ultimately in ensuring survival. Bacteria serve as useful biosensors in industry and clinical diagnostics, in addition to producing drugs for therapeutic purposes. Therefore, there is a great demand for engineered bacterial strains that contain transmembrane signalling systems with high molecular specificity, sensitivity and dose dependency. In this review, we address the complexity of transmembrane signalling systems and discuss principles to rewire receptors and their signalling outputs.
Combined Cancer Photothermal-Chemotherapy Based on Doxorubicin/Gold Nanorod-Loaded Polymersomes

Gold nanorods (GNRs) are well known in photothermal therapy based on near-infrared (NIR) laser absorption of the longitudinal plasmon band. Herein, we developed an effective stimulus system -- GNRs and doxorubicin co-loaded polymersomes (P-GNRs-DOX) -- to facilitate co-therapy of photothermal and chemotherapy. DOX can be triggered to release once the polymersomes are corrupted under local hyperthermic condition of GNRs induced by NIR laser irradiation. Also, the cytotoxicity of GNRs caused by the residual cetyltrimethylacmmonium bromide (CTAB) was reduced by shielding the polymersomes. The GNRs-loaded polymersomes (P-GNRs) can be efficiently taken up by the tumor cells. The distribution of the nanomaterial was imaged by IR-820 and quantitatively analyzed by ICP-AES. We studied the ablation of tumor cells in vitro and in vivo, and found that co-therapy offers significantly improved therapeutic efficacy (tumors were eliminated without regrowth.) compared with chemotherapy or photothermal therapy alone. By TUNEL immunofluorescent staining of tumors after NIR laser irradiation, we found that the co-therapy showed more apoptotic tumor cells than the other groups. Furthermore, the toxicity study by pathologic examination of the heart tissues demonstrated a lower systematic toxicity of P-GNRs-DOX than free DOX. Thus, the chemo-photothermal treatment based on polymersomes loaded with DOX and GNRs is a useful strategy for maximizing the therapeutic efficacy and minimizing the dosage-related side effects in the treatment of solid tumors.
EXPERIMENTAL DEGRADATION CHARACTERIZATION OF PLA-PCL , PGA-PCL , PDO AND PGA FIBRES

Aliphatic polyesters, such as polylactic acid (PLA), polyglycolic acid (PGA), polycaprolactone (PCL) and polydioxone (PDO), have been commonly used, alone or combined in blends or composites, in a variety of application on different markets. In the case of commodity products, biodegradable plastics claim clear environmental advantages in several brief use applications, mainly in the final stage of life (waste disposal), which can clearly be evident through life cycle assessment. In the biomedical field, an important application is on regenerative medicine, where they temporarily replace the biomechanical functions while the natural tissue regenerates. They have been also used in many controlled drugs release devices.
Comparison of SARIMA, NARX and BPNN models in forecasting time series data of network traffic

The investigation and forecasting network traffic usage is an essential concern in the academic activities of university. This paper reports how to apply and compare SARIMA, NARX, and BPNN by using short-term time series datasets. The network traffic datasets are obtained from the ICT Universitas Mulawarman. As a result, the determination of several prediction models will continue to be an alternative for researchers to obtain more accurate prediction results. The first analysis used the SARIMA ((2,1,1)(2,1,2)12) with MSE of 0.064 indicated that it was a good model. The second analysis used the NARX models by using architecture 189∶31∶94 with performance value of MSE was 0.006717 respectively. The third one used the BPNN with two-hidden-layers (5-10-10-1) architecture with MSE value of 0.00942479. Finally, we compared the performance of methods using MSE. Based on the experiment, the artificial neural networks (ANN) i.e., NARX and BPNN models have been successfully to support the time series datasets in order to predict the future.
Automatic Detection of Webpages that Share the Same Web Template

This work has been partially supported by the Spanish Ministerio de Econom´ia y Competitividad (Secretar´ia de Estado de Investigacion, Desarrollo e Innovaci ´ on) ´ under grant TIN2013-44742-C4-1-R and by the Generalitat Valenciana under grant PROMETEO/2011/052. David Insa was partially supported by the Spanish Ministerio de Eduacion under FPU grant AP2010-4415. Salvador Tamarit was partially supported by research project POLCA, Programming Large Scale Heterogeneous Infrastructures (610686), funded by the European Union, STREP FP7.
WEB-BASED ACT FOR STUDENTS 1 Web-based acceptance and commitment therapy for mental health problems in college students : A randomized controlled trial

There are significant challenges in addressing the mental health needs of college students. The current study tested an acceptance and commitment therapy (ACT) web-based self-help program to treat a broad range of psychological problems students struggle with. A sample of 79 college students were randomized to web-based ACT or a waitlist condition, with assessments at baseline and posttreatment. Results indicated adequate acceptability and program engagement for the ACT website. Relative to waitlist, participants receiving ACT improved on overall distress, general anxiety, social anxiety, depression, academic concerns, and positive mental health. There were no between group effects on eating concerns, alcohol use, or hostility or on some key ACT process of change measures. ACT participants improved more on mindful acceptance and obstruction to valued living, both of which mediated treatment outcomes. Results are discussed in the context of lessons learned with the website prototype, and areas for further research are presented.