Miracle-dz/UniFAR-FTUs huggingface dataset:
Customizing the Computation Capabilities of Microprocessors

Designers of microprocessor-based systems must constantly improve performance and increase computational efficiency in their designs to create value. To this end, it is increasingly common to see computation accelerators in general-purpose processor designs. Computation accelerators collapse portions of an application's dataflow graph, reducing the critical path of computations, easing the burden on processor resources, and reducing energy consumption in systems. There are many problems associated with adding accelerators to microprocessors, though. Design of accelerators, architectural integration, and software support all present major challenges. This dissertation tackles these challenges in the context of accelerators targeting acyclic and cyclic patterns of computation. First, a technique to identify critical computation subgraphs within an application set is presented. This technique is hardware-cognizant and effectively generates a set of instruction set extensions given a domain of target applications. Next, several general-purpose accelerator structures are quantitatively designed using critical subgraph analysis for a broad application set. The next challenge is architectural integration of accelerators. Traditionally, software invokes accelerators by statically encoding new instructions into the application binary. This is incredibly costly, though, requiring many portions of hardware and software to be redesigned. This dissertation develops strategies to utilize accelerators, without changing the instruction set. In the proposed approach, the microarchitecture translates applications at run-time, replacing computation subgraphs with microcode to utilize accelerators. We explore the tradeoffs in performing difficult aspects of the translation at compile-time, while retaining run-time replacement. This culminates in a simple microarchitectural interface that supports a plug-and-play model for integrating accelerators into a pre-designed microprocessor. Software support is the last challenge in dealing with computation accelerators. The primary issue is difficulty in generating high-quality code utilizing accelerators. Handwritten assembly code is standard in industry, and if compiler support does exist, simple greedy algorithms are common. In this work, we investigate more thorough techniques for compiling for computation accelerators. Where greedy heuristics only explore one possible solution, the techniques in this dissertation explore the entire design space, when possible. Intelligent pruning methods ensure that compilation is both tractable and scalable.
A Flexible Transaction Framework for Dynamic Collaboration of Agents - with an Online Travel Application

The advancement of Internet-based commerce has created a turbulent market environment by allowing easier introduction of new products, services, and suppliers. For this dynamic environment, information systems need to be designed in a flexible way to meet the changing requirements. This paper proposes a flexible transaction framework for multi-agent systems so that agent systems can adapt to various types of changes in the dynamic electronic market environment. The flexible transaction framework consists of a flexible conversation model (FCM) for agents and an ontology meta-model called TOO (Task-Oriented Ontology) for the specific requirements of FCM. FCM permits agents to use newly acquired conversation policies that are induced by the frequent changes in transaction methods. Since FCM requires agents to be aware of a broader set of ontology entities, TOO is used to reduce the complexity of the ontology design and implementation for FCM. The flexible transaction framework is illustrated with an online traveling system developed for Korean domestic transportation services. The prospective synergy between the present work and Web services is discussed in the discussion section.
Quand devons-nous utiliser l'algorithme EM pour effectuer un apprentissage de structure de RB ?

De nombreuses methodes d'apprentissage de reseaux bayesiens sont apparues durant ces deux dernieres decenies. Neanmoins, peu de techniques proposent actuellement d'effectuer un tel travail lorsque la base d'exemples est incomplete. Nous avons adapte certains algorithmes gloutons a cette tâche en utilisant soit l'algorithme Expectation-Maximisation, soit la methode Pairwise Deletion. La methode EM s'avere etre la plus communement utilisee pour traiter les bases incompletes. Cependant, a travers une etude experimentale basee sur l'exemple bien connu d'ASIA, nous allons montrer que l'utilisation de cet algorithme ne doit pas etre favorisee dans toutes circonstances.
Approximating Discrete Probability Distribution of Image Emotions by Multi-Modal Features Fusion

Existing works on image emotion recognition mainly assigned the dominant emotion category or average dimension values to an image based on the assumption that viewers can reach a consensus on the emotion of images. However, the image emotions perceived by viewers are subjective by nature and highly related to the personal and situational factors. On the other hand, image emotions can be conveyed by different features, such as semantics and aesthetics. In this paper, we propose a novel machine learning approach that formulates the categorical image emotions as a discrete probability distribution (DPD). To associate emotions with the extracted visual features, we present a weighted multi-modal shared sparse leaning to learn the combination coefficients, with which the DPD of an unseen image can be predicted by linearly integrating the DPDs of the training images. The representation abilities of different modalities are jointly explored and the optimal weight of each modality is automatically learned. Extensive experiments on three datasets verify the superiority of the proposed method, as compared to the state-of-the-art.
Origins of projections from the inferior colliculus to the cochlear nucleus in guinea pigs

We used retrograde tracing techniques to examine the projections from the inferior colliculus to the cochlear nucleus in guinea pigs. Following injection of a retrograde tracer into one cochlear nucleus, labeled cells were found bilaterally in all subdivisions of the inferior colliculus. The majority of cells were located in the central nucleus and external cortex; relatively few cells were located in the dorsal cortex. Multipolar (stellate) cells were labeled in all subdivisions of the inferior colliculus. In the central nucleus, disk‐shaped cells were also labeled. To determine whether individual collicular neurons send collateral projections to the cochlear nuclei on both sides, we injected different fluorescent tracers into left and right cochlear nuclei in the same animal. The inferior colliculi contained very few double‐labeled cells, indicating that the projections to ipsilateral and contralateral cochlear nuclei originate from separate populations of cells. J. Comp. Neurol. 429:206–220, 2001. © 2000 Wiley‐Liss, Inc.
The Industrialized Building System (IBS) Survey Report 2008--Educating the Malaysian Construction Industry

The IBS Survey report 2008 continues a practice that began in 2003. The first report was published in 2003 followed by in 2005 and recently in 2008. It records recent trends in selected areas that reflect the Malaysia's achievement of IBS usage in the building construction industry. Due to dynamic economic and technological changes, IBS usage reports have been increasingly important. The design of quantitative survey in IBS acceptance questionnaire design is based on the Technology Acceptance Model (TAM) and verified the reliability of questionnaire design by alpha-Cronbach. The result of alpha-Cronbach on IBS acceptance questionnaire is 0.787 which is round out to 0.8. The re-arrangements of items in the questionnaire design and the validity of the questionnaire has been checked and found to be valid. The awareness of using IBS in the construction industry in Malaysia has been successfully measured based on the IBS actual use, perceived ease of IBS use and perceived IBS usefulness with a scoring of alpha-Cronbach 0.861, 0.744 and 0.853 respectively.
IL-5 Promotes Eosinophil Trafficking to the Esophagus1

Eosinophil infiltration into the esophagus occurs in a wide range of diseases; however, the underlying pathophysiological mechanisms involved are largely unknown. We now report that the Th2 cytokine, IL-5, is necessary and sufficient for the induction of eosinophil trafficking to the esophagus. We show that transgenic mice overexpressing IL-5 under the control of a T cell (CD2) or a small intestinal enterocyte (fatty acid-binding protein) promoter have markedly increased eosinophil numbers in the esophagus. For example, esophageal eosinophil levels are 1.9 ± 0.9 and 121 ± 14 eosinophils/mm2 in wild-type and CD2-IL-5-transgenic mice, respectively. Consistent with this effect being mediated by a systemic mechanism, pharmacological administration of IL-5 via a miniosmotic pump in the peritoneal cavity resulted in blood and esophageal eosinophilia. To examine the role of IL-5 in oral Ag-induced esophageal eosinophilia, eosinophilic esophagitis was induced by allergen exposure in IL-5-deficient and wild-type mice. Importantly, IL-5-deficient mice were resistant to eosinophilic esophagitis. Finally, we examined the role of eotaxin when IL-5 was overproduced in vivo. Esophageal eosinophil levels in CD2-IL-5-transgenic mice were found to decrease 15-fold in the absence of the eotaxin gene; however, esophageal eosinophil numbers in eotaxin-deficient IL-5-transgenic mice still remained higher than wild-type mice. In conclusion, these studies demonstrate a central role for IL-5 in inducing eosinophil trafficking to the esophagus.
Renal extracapsular hypoechoic rim and kidney cortical thickness.

OBJECTIVES A renal extracapsular hypoechoic rim was previously recognized and interpreted as a typical sonographic finding of renal failure. Subsequently it was hypothesized that the hypoechoic rim could be produced by a state of sodium retention and oedema caused by nephropathy but not necessarily associated with renal failure. In order to get this cleared we performed a retrospective analysis of 80 renal ultrasound examinations, carried out at our center, in 41 of which it was found a renal extracapsular hypoechoic rim. MATERIALS AND METHODS For each patient we recorded the glomerular filtration rate, the diameters in the longitudinal axis, the resistive indexes and the cortical thickness of each kidney, the possible presence and thickness of the hypoechoic rim and yet the possible coexistence of diabetes mellitus, proteinuria and clinical signs of fluid overload as peripheral oedema, distended jugular veins, ascites, increased caliber and reduced respiratory excursion of the vena cava. RESULTS The F value calculated to assess the weight/influence on the hypoechoic rim of each of the variables showed as all variables, except the sex, significantly weighed on the hypoechoic rim although the greatest weight was reached by a glomerular filtration rate < 60 ml/min/1.73 m2 and a renal cortical thickness between 7 and 12 mm. The hypoechoic rim was found only when cortical thickness was between 7 and 12 mm while it was absent if the cortical thickness was less than 7 or greater than 12 mm. We also found numerous cases of sidedness of the hypoechoic rim. CONCLUSIONS It is our opinion that in case of unilateral finding of an hypoechoic rim, the association between the hypoechoic rim and the cortical thinning is consistent and therefore more accurate than the correlation between the presence of the hypoechoic rim and the reduction of the glomerular filtration rate.
Chlamydomonas reinhardtii Phosphoribulokinase : Sequence, Purification, and Kinetics.

The sequence and kinetic properties of phosphoribulokinase purified from Chlamydomonas reinhardtii were determined and compared with the spinach (Spinacea oleracea) enzyme. Chlamydomonas phosphoribulokinase was purified to apparent homogeneity, with a specific activity of 410 micromoles per minute per milligram. Polyclonal antibodies to the purified protein were used to isolate a Chlamydomonas cDNA clone, which, upon sequencing, was found to contain the entire coding region. The transit peptide cleavage site was determined by Edman analysis of the mature protein. The precursor protein consists of a 31 amino acid transit peptide and a 344 amino acid mature polypeptide. The mature polypeptide has a calculated molecular weight of 38.5 kilodaltons and a pl of 5.75. The V(max) of the purified enzyme was 465 micromoles per minute per milligram, with apparent K(m) values of 62 micromolar ATP and 56 micromolar ribulose 5-phosphate. Immunoblot analysis indicated antigenic similarity and a similar subunit size for the enzyme from five higher plant species and Chlamydomonas. Southern blot analysis of Chlamydomonas genomic DNA indicated the presence of a single phosphoribulokinase gene. Comparison of the mature proteins from Chlamydomonas and spinach revealed 86 amino acid differences in primary structure (25% of the total) without a major difference in kinetic properties. The transit peptides of the spinach and Chlamydomonas proteins possessed little sequence homology.
The Impact of Tourism on Small Business Performance: Empirical Evidence from Malaysian Islands

The tourism industry has become an important sector to both developed and developing countries, including Malaysia. Acknowledging positive advantages of tourism, much research has been carried out on small business in the tourism industry. However, direct impact of tourism on business performance is totally ignored. This paper presents an empirical result of a study on the impact of tourism on small businesses performance operating on four main tourist destination islands in Malaysia. Employing primary data collected from small tourism businesses on the four islands and a multiple regression analysis, this study found that tourism as measured by tourist arrivals and tourist customers has significant positive impact on the financial and non-financial performance of the small businesses. This finding consolidates tourism development theory that tourism is an important catalyst for entrepreneurial development and small business performance. It also justifies the government efforts in promoting and developing the tourism industry in general and island tourism in particular. Field of Research: Tourism, small business, performance, Malaysia
High-pressure studies with x-rays using diamond anvil cells

Pressure profoundly alters all states of matter. The symbiotic development of ultrahigh-pressure diamond anvil cells, to compress samples to sustainable multi-megabar pressures; and synchrotron x-ray techniques, to probe materials’ properties in situ, has enabled the exploration of rich high-pressure (HP) science. In this article, we first introduce the essential concept of diamond anvil cell technology, together with recent developments and its integration with other extreme environments. We then provide an overview of the latest developments in HP synchrotron techniques, their applications, and current problems, followed by a discussion of HP scientific studies using x-rays in the key multidisciplinary fields. These HP studies include: HP x-ray emission spectroscopy, which provides information on the filled electronic states of HP samples; HP x-ray Raman spectroscopy, which probes the HP chemical bonding changes of light elements; HP electronic inelastic x-ray scattering spectroscopy, which accesses high energy electronic phenomena, including electronic band structure, Fermi surface, excitons, plasmons, and their dispersions; HP resonant inelastic x-ray scattering spectroscopy, which probes shallow core excitations, multiplet structures, and spin-resolved electronic structure; HP nuclear resonant x-ray spectroscopy, which provides phonon densities of state and time-resolved Mössbauer information; HP x-ray imaging, which provides information on hierarchical structures, dynamic processes, and internal strains; HP x-ray diffraction, which determines the fundamental structures and densities of single-crystal, polycrystalline, nanocrystalline, and non-crystalline materials; and HP radial x-ray diffraction, which yields deviatoric, elastic and rheological information. Integrating these tools with hydrostatic or uniaxial pressure media, laser and resistive heating, and cryogenic cooling, has enabled investigations of the structural, vibrational, electronic, and magnetic properties of materials over a wide range of pressure-temperature conditions.
Why does PairDiff work? - A Mathematical Analysis of Bilinear Relational Compositional Operators for Analogy Detection

Representing the semantic relations that exist between two given words (or entities) is an important first step in a wide-range of NLP applications such as analogical reasoning, knowledge base completion and relational information retrieval. A simple, yet surprisingly accurate method for representing a relation between two words is to compute the vector offset (PairDiff) between their corresponding word embeddings. Despite the empirical success, it remains unclear as to whether PairDiff is the best operator for obtaining a relational representation from word embeddings. We conduct a theoretical analysis of generalised bilinear operators that can be used to measure the l2 relational distance between two word-pairs. We show that, if the word embed- dings are standardised and uncorrelated, such an operator will be independent of bilinear terms, and can be simplified to a linear form, where PairDiff is a special case. For numerous word embedding types, we empirically verify the uncorrelation assumption, demonstrating the general applicability of our theoretical result. Moreover, we experimentally discover PairDiff from the bilinear relational compositional operator on several benchmark analogy datasets.
Accommodation of the human lens capsule using a finite element model based on nonlinear regionally anisotropic biomembranes

Accommodation of the eyes, the mechanism that allows humans to focus their vision on near objects, naturally diminishes with age via presbyopia. People who have undergone cataract surgery, using current surgical methods and artificial lens implants, are also left without the ability to accommodate. The process of accommodation is generally well known; however the specific mechanical details have not been adequately explained due to difficulties and consequences of performing in vivo studies. Most studies have modeled the mechanics of accommodation under assumptions of a linearly elastic, isotropic, homogenous lens and lens capsule. Recent experimental and numerical studies showed that the lens capsule exhibits nonlinear elasticity and regional anisotropy. In this paper we present a numerical model of human accommodation using a membrane theory based finite element approach, incorporating recent findings on capsular properties. This study seeks to provide a novel perspective of the mechanics of accommodation. Such findings may prove significant in seeking biomedical solutions to restoring loss of visual power.
Nonflammable perfluoropolyether-based electrolytes for lithium batteries

Significance This research article describes a unique class of nonflammable electrolytes for lithium-ion batteries that are based on functionalized perfluoropolyethers (PFPEs). It demonstrates that PFPEs may be used as a major component in operating batteries. These electrolytes not only are completely nonflammable, but they also exhibit unprecedented high transference numbers and low electrochemical polarization, indicative of longer battery life. The results in this work may represent a significant step toward a lithium-ion battery with improved safety and pave the way for the development of new electrolytes that can address the persisting challenges of current battery technologies. The flammability of conventional alkyl carbonate electrolytes hinders the integration of large-scale lithium-ion batteries in transportation and grid storage applications. In this study, we have prepared a unique nonflammable electrolyte composed of low molecular weight perfluoropolyethers and bis(trifluoromethane)sulfonimide lithium salt. These electrolytes exhibit thermal stability beyond 200 °C and a remarkably high transference number of at least 0.91 (more than double that of conventional electrolytes). Li/LiNi1/3Co1/3Mn1/3O2 cells made with this electrolyte show good performance in galvanostatic cycling, confirming their potential as rechargeable lithium batteries with enhanced safety and longevity.
Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke.

BACKGROUND Recurrent stroke is a frequent, disabling event after ischemic stroke. This study compared the efficacy and safety of two antiplatelet regimens--aspirin plus extended-release dipyridamole (ASA-ERDP) versus clopidogrel. METHODS In this double-blind, 2-by-2 factorial trial, we randomly assigned patients to receive 25 mg of aspirin plus 200 mg of extended-release dipyridamole twice daily or to receive 75 mg of clopidogrel daily. The primary outcome was first recurrence of stroke. The secondary outcome was a composite of stroke, myocardial infarction, or death from vascular causes. Sequential statistical testing of noninferiority (margin of 1.075), followed by superiority testing, was planned. RESULTS A total of 20,332 patients were followed for a mean of 2.5 years. Recurrent stroke occurred in 916 patients (9.0%) receiving ASA-ERDP and in 898 patients (8.8%) receiving clopidogrel (hazard ratio, 1.01; 95% confidence interval [CI], 0.92 to 1.11). The secondary outcome occurred in 1333 patients (13.1%) in each group (hazard ratio for ASA-ERDP, 0.99; 95% CI, 0.92 to 1.07). There were more major hemorrhagic events among ASA-ERDP recipients (419 [4.1%]) than among clopidogrel recipients (365 [3.6%]) (hazard ratio, 1.15; 95% CI, 1.00 to 1.32), including intracranial hemorrhage (hazard ratio, 1.42; 95% CI, 1.11 to 1.83). The net risk of recurrent stroke or major hemorrhagic event was similar in the two groups (1194 ASA-ERDP recipients [11.7%], vs. 1156 clopidogrel recipients [11.4%]; hazard ratio, 1.03; 95% CI, 0.95 to 1.11). CONCLUSIONS The trial did not meet the predefined criteria for noninferiority but showed similar rates of recurrent stroke with ASA-ERDP and with clopidogrel. There is no evidence that either of the two treatments was superior to the other in the prevention of recurrent stroke. (ClinicalTrials.gov number, NCT00153062.)
Speed-Accuracy Trade-Off in a Trajectory-Constrained Self-Feeding Task

Motor speed and accuracy are both affected in childhood dystonia. Thus, deriving a speed-accuracy function is an important metric for assessing motor impairments in dystonia. Previous work in dystonia studied the speed-accuracy trade-off during point-to-point tasks. To achieve a more relevant measurement of functional abilities in dystonia, the present study investigates upper-limb kinematics and electromyographic activity of 8 children with dystonia and 8 healthy children during a trajectory-constrained child-relevant task that emulates self-feeding with a spoon and requires continuous monitoring of accuracy. The speed-accuracy trade-off is examined by changing the spoon size to create different accuracy demands. Results demonstrate that the trajectory-constrained speed-accuracy relation is present in both groups, but it is altered in dystonia in terms of increased slope and offset toward longer movement times. Findings are consistent with the hypothesis of increased signal-dependent noise in dystonia, which may partially explain the slow and variable movements observed in dystonia.