Miracle-dz/UniFAR-FTUs huggingface dataset:
True Enough: Learning to Live in a Post-Fact Society

Introduction: Why Facts No Longer Matter. 1. "Reality" Is Splitting. 2. The New Tribalism: Swift Boats and the Power of Choosing. 3. Trusting Your Senses: Selective Perception and 9/11. 4. Questionable Expertise: The Stolen Election and the Men Who Push It. 5. The Twilight of Objectivity, or What's the Matter with Lou Dobbs? 6. "Truthiness" Everywhere. Epilogue: Living In a World without Trust. Acknowledgments. Notes. Index.
Tobacco quitlines: looking back and looking ahead

Telephone based tobacco cessation services, or quitlines, have become central components of many comprehensive tobacco control programmes. This paper provides an overview of their history, noting milestones in the growth of quitlines. Key factors in their worldwide adoption were solid evidence from clinical trials with large community samples and strong backing from public health officials. Quitlines are now available throughout most of North America, Europe, Australia and in many other locations around the world. The paper also offers several recommendations for future directions in quitline practice and research. Benchmarks should be established for key areas of quitline implementation, such as accessibility, quality and cost efficiency. Advances in pharmacotherapy, telephony and web based applications should be investigated for opportunities to expand service offerings. Research and development are needed to determine how best to serve a diverse clientele in the most cost effective manner. Funding should be expanded and diversified to enable quitlines to serve much larger numbers of users. Healthcare providers should be targeted for quitline promotion, to engage them in a broad effort to increase the number of patients receiving cessation messages from clinicians. The goal of quitline promotion should expand to include an increase in unaided quit attempts in the population. Early research findings were quickly adopted in quitline practice, and future research to answer questions that have arisen through the implementation of quitlines will probably also find quick adoption.
Thiopurine Drugs Repositioned as Tyrosinase Inhibitors

Drug repositioning is the application of the existing drugs to new uses and has the potential to reduce the time and cost required for the typical drug discovery process. In this study, we repositioned thiopurine drugs used for the treatment of acute leukaemia as new tyrosinase inhibitors. Tyrosinase catalyses two successive oxidations in melanin biosynthesis: the conversions of tyrosine to dihydroxyphenylalanine (DOPA) and DOPA to dopaquinone. Continuous efforts are underway to discover small molecule inhibitors of tyrosinase for therapeutic and cosmetic purposes. Structure-based virtual screening predicted inhibitor candidates from the US Food and Drug Administration (FDA)-approved drugs. Enzyme assays confirmed the thiopurine leukaemia drug, thioguanine, as a tyrosinase inhibitor with the inhibitory constant of 52 μM. Two other thiopurine drugs, mercaptopurine and azathioprine, were also evaluated for their tyrosinase inhibition; mercaptopurine caused stronger inhibition than thioguanine did, whereas azathioprine was a poor inhibitor. The inhibitory constant of mercaptopurine (16 μM) was comparable to that of the well-known inhibitor kojic acid (13 μM). The cell-based assay using B16F10 melanoma cells confirmed that the compounds inhibit mammalian tyrosinase. Particularly, 50 μM thioguanine reduced the melanin content by 57%, without apparent cytotoxicity. Cheminformatics showed that the thiopurine drugs shared little chemical similarity with the known tyrosinase inhibitors.
Stress, Anxiety and Depression Among Parents of Children With Autism Spectrum Disorder

In a replication of a previous study of the incidence and contributing factors in anxiety, depression and stress in Victorian parents of a child with autism spectrum disorder (ASD), a sample of 107 Gold Coast parents completed a questionnaire that assessed their demographic backgrounds, anxiety and depression scores on standardised inventories, and also tapped several aspects of those factors that may have contributed to their wellbeing. Over 90% of parents reported that they were sometimes unable to deal effectively with their child's behaviour. Nearly half of the participants were severely anxious and nearly two thirds were clinically depressed. Factors that emerged as significant in differentiating between parents with high versus low levels of anxiety and depression included access to family support, parents' estimation of family caregivers' expertise in dealing with the behavioural difficulties of a child with ASD, and parental health. Parents' suggestions for personal support services are reported, and some comparisons across the data from the two states are made, with suggestions for further research into parent support mechanisms.
Towards native higher-order remote procedure calls

We present a new abstract machine, called DCESH, which models the execution of higher-order programs running in distributed architectures. DCESH implements a native general remote higher-order function call across node boundaries. It is a modernised version of SECD enriched with specialised communication features required for implementing the remote procedure call mechanism. The key correctness result is that the termination behaviour of the remote procedure call is indistinguishable (bisimilar) to that of a local call. The correctness proofs and the requisite definitions for DCESH and other related abstract machines are formalised using Agda. We also formalise a generic transactional mechanism for transparently handling failure in DCESHs. We use the DCESH as a target architecture for compiling a conventional call-by-value functional language ("Floskel") which can be annotated with node information. Conventional benchmarks show that the single-node performance of Floskel is comparable to that of OCaml, a semantically similar language, and that distribution overheads are not excessive.
ModifRoundtrip: A Model-Based tool to reuse legacy transformations

The legacy transformations dealing with domain specific data gathers important expertise. Nevertheless, in many cases, have to be rewritten in order to make them apply to semantically equivalent but structurally incompatible data. According to the complexity of the transformation, rewriting them can quickly become a difficult and error-prone task. We propose a coevolution approach to enable the reuse of legacy transformations instead of their rewriting. In this approach, the data conforming to the reuse context coevolve into data conforming to the legacy transformation context. Legacy transformation is applied and the result is migrated back to the reuse context. In this paper, we introduce ModifRoundtrip, a plug-in for the Eclipse development environment. It promotes the reuse of legacy transformations, providing guidance for the user during reuse process. Reuse process is done automatically, but ModifRoundtrip provides interaction points to the user to indicate custom reuse scenarios. A tool demonstration video is available at: https://youtu.be/iAPul2httyE.
Baseline results for the challenge problem of HumanID using gait analysis

Identification of people from gait captured on video has become a challenge problem in computer vision. However there is not a baseline algorithm or standard dataset for measuring, or determining what factors affect performance. In fact, the conditions under which the problem is "solvable" are not understood or characterized. This paper describes a large set of video sequences (about 300 GB of data related to 452 sequences from 74 subjects) acquired to investigate important dimensions of this problem, such as variations due to viewpoint, footwear, and walking surface. We introduce the HumanID challenge problem. The challenge problem contains a set of experiments of increasing difficulty, a baseline algorithm, and its performance on the challenge problem. Our results suggest that differences in footwear or walking surface type between the gallery and probe video sequence are factors that affect performance. The data set, the source code for the baseline algorithm, and UNIX scripts to reproduce the basic results reported are available to the research community at http://marathon.csee. usf.edu/GaitBaseline/.
Metric 1-Median Selection

Consider the problem of finding a point in a metric space ({ 1,2,…, n}, d) with the minimum average distance to other points. We show that this problem has no deterministic o(n1+1/(h-1)/h)-query 2h· (1-ϵ))-approximation algorithms for any constant ϵ >0 and any h=h(n)∈ Z+ \ {1} satisfying h=o(n1/(h-1)). Combining our result with existing ones, we determine the best approximation ratio achievable by deterministic O(n1+ϵ)-query (respectively, O(n1+ϵ)-time) algorithms to be 2⌈ 1/ϵ ⌉, for all constants ϵ ∈ (0,1).
Updates Through Views: A New Hope

Database views are extensively used to represent unmaterialized tables. Applications rarely distinguish between a materialized base table and a virtual view, thus, they may issue update requests on the views. Since views are virtual, update requests on them need to be translated to updates on the base tables. Existing literature has shown the difficulty of translating view updates in a side-effect free manner. To address this problem, we propose a novel approach for separating the data instance into a logical and a physical level. This separation allows us to achieve side-effect free translations of any kind of update on the view. Furthermore, deletes on a view can be translated without affecting the base tables. We describe the implementation of the framework and present our experimental results
The Algebra of Observables of the Closed Bosonic Nambu-Goto-String: The Presentation of the Algebra of Classical Observables for Light-Like Energy-Momentum in 3+1 Dimensions

The presentation of the algebra of classical observables of the closed bosonic Nambu-Goto-String in 3+1 dimensions is given for the massless case $P^2=0,P\neq0$ in the relevant standard frame up to and including the second stratum. The elements and the relations of this algebra established so far are presented in the form of irreducible multiplets of the stabilizer group $E_2$ of the light-like vector $P$ in its standard form.
ROSENBLUTH INTERNATIONAL : COMPETING IN THE DIGITAL ECONOMY ➥

LEARNING OBJECTIVES After studying this chapter, you will be able to: ᕡ Describe strategic information systems (SISs) and explain their advantages. ᕢ Describe Porter's competitive forces model and how information technology helps companies improve their competitive positions. ᕣ Describe 12 strategies companies can use to achieve competitive advantage in their industry. ᕤ Describe Porter's value chain model and its relationship to information technology. ᕥ Describe how linking information systems across organizations helps companies achieve competitive advantage. ᕦ Describe global competition and global business drivers. ᕧ Describe representative SISs and the advantage they provide to organizations. ᕨ Discuss the challenges associated with sustaining competitive advantage.
Catastrophic Job Destruction

In this article we study the resilience of the Portuguese labor market, in terms of job flows, employment and wage developments, in the context of the current recession. We single out the huge contribution of job destruction, especially due to the closing of existing firms, to the dramatic decline of total employment and increase of the unemployment rate. We also document the very large increase in the incidence of minimum wage earners and nominal wage freezes. We explored three different channels that may have amplified the employment response to the great recession: the credit channel, the wage rigidity channel, and the labor market segmentation channel. We uncovered what we believe is convincing evidence that the severity of credit constraints played a significant role in the current job destruction process. Wage rigidity is seen to be associated with lower net job creation and higher failure rates of firms. Finally, labor market segmentation seemed to have favored a stronger job destruction that was facilitated by an increasing number of temporary workers Dans cet article, nous analysons la resilience du marche du travail portugais, en termes de mouvements de main d’oeuvre, d'emplois et d'evolution des salaires, dans le contexte de la recession actuelle. Nous mettons en evidence la contribution significative des destructions d'emplois, notamment en raison des fermetures d’entreprises, a la baisse importante de l'emploi total et a l'augmentation du taux de chomage. Nous examinons egalement le tres fort accroissement du nombre de travailleurs remuneres au salaire minimum et le gel des salaires nominaux. Nous explorons trois differentes causes pouvant avoir amplifie la reaction de l'emploi a la grande recession : l’acces au credit, la rigidite des salaires, et la segmentation du marche du travail. Nous mettons en lumiere une preuve, que nous jugeons convaincante, que la rigueur des contraintes de credit pesant sur les entreprises a joue un role important dans le processus actuel de destruction d’emplois. La rigidite des salaires est consideree comme allant de pair avec une creation nette d'emplois plus faible et des taux plus eleves de faillite d'entreprises. Enfin, la segmentation du marche du travail semble avoir favorise des destructions d'emplois plus fortes rendues possibles par un nombre croissant de travailleurs temporaires.
Cognitive economy and satisficing in information seeking: A longitudinal study of undergraduate information behavior

This paper reports on a longitudinal study of information seeking by undergraduate Information Management students. It describes how they found and used information, and explores their motivation and decision making. We employed a use–in-context approach where students were observed conducting, and interviewed about, information seeking tasks carried out during their academic work. We found that participants were reluctant to engage with a complex range of information sources, preferring to use the internet. The main driver for progress in information seeking was the immediate demands of their work (e.g. assignments). Students used their growing expertise to justify a conservative information strategy, retaining established strategies as far as possible and completing tasks with minimum information seeking effort. The time cost of using library material limited the uptake of such resources. New methods for discovering and selecting information were only adopted when immediately relevant to the task at hand, and tasks are generally chosen or interpreted in ways that minimised the need to develop new strategies. Students were driven by the demands of the task to use different types of information resources, but remained reluctant to move beyond keyword searches, even when they proved ineffective. They also lacked confidence in evaluating the relative usefulness of resources. Whereas existing literature on satisficing has focused on stopping conditions, this work has highlighted a richer
Long‐Term Risk of Stroke in Patients With Type 1 and Type 2 Diabetes Following Coronary Artery Bypass Grafting

Background We performed a nationwide population‐based cohort study to investigate the long‐term risk of stroke after coronary artery bypass grafting in patients with type 1 and type 2 diabetes. Methods and Results All patients who underwent primary coronary artery bypass grafting in Sweden from 2000 through 2011 were included from the SWEDEHEART register. We excluded patients with prior stroke, and patients who had a stroke or died within 30 days of surgery. The National Diabetes Register was used to identify patients with type 1 and type 2 diabetes. Incident stroke (ischemic and hemorrhagic), and all‐cause mortality was obtained by record linkage with the National Patient Register and the Cause of Death register. We used multivariable Cox regression to estimate the risk of stroke in relation to type of diabetes. A total of 53 820 patients (type 1 diabetes [n=714], type 2 diabetes [n=10 054], no diabetes [n=43 052]) were included. During a mean follow‐up of 7.4 years (398 337 person‐years), in total, 8.0% (n=4296) of the patients had a stroke: 7.3% (n=52) in patients with type 1 diabetes, 9.1% (n=915) in patients with type 2 diabetes, and 7.7% (n=3329) in patients with no diabetes. The multivariable adjusted hazard ratio (95% CI) for all stroke was 1.59 (1.20–2.11) in type 1 diabetes, and 1.32 (1.23–1.43) in type 2 diabetes. Conclusions The long‐term risk for stroke after coronary artery bypass grafting was increased in patients with type 1 and type 2 diabetes, compared to patients with no diabetes.
Factoring Modular Polynomials

This paper gives an algorithm to factor a polynomialf(in one variable) over rings like Z/rZ forr? Z or Fy/rFy forr? Fy. The Chinese Remainder Theorem reduces our problem to the case whereris a prime power. Then factorization is not unique, but ifrdoes not divide the discriminant off, our (probabilistic) algorithm produces a description of all (possibly exponentially many) factorizations into irreducible factors in polynomial time. Ifrdivides the discriminant, we only know how to factor by exhaustive search, in exponential time.
Assessment report on Curcuma longa L., rhizoma

of on in group aqueous of C. longa and Verapamil administrated in and 3 after drug were euthanized and Verapamil as well as C. longa the of in gall in comparison to Similar action on bile secretion (possibly via p-glycoprotein) by Verapamil and C. longa the same method. To determine the mechanism of action the extracts were tested for adipocyte differentiation. No differences in bodyweight were observed between treated and control animals. The ethanolic extract stimulated adipocyte differentiation dose-dependently. The hexanic extract and the ethanolic extract from the residue of the hexane extraction showed similar effects but at higher concentration as the ethanolic extract. The results indicate that turmeric ethanolic extract containing both curcuminoids and sesquiterpenoids is more strongly hypoglycemic than either curcuminoids or sesquiterpenoids (Nishiyama et al., 2005).
Extended NCS Based on Method of Series Reversion for Imaging of Highly Squinted SAR

In the case of high range resolution and squint angle, current chirp scaling algorithm (CSA) and nonlinear CSA (NCSA) have a finite ability to achieve high-quality images. The problem stems from a range-dependent (i.e., space-variant) cubic- and higher order terms of range frequency, which require sufficient compensation or space-variant filtering, in the phase of the synthetic aperture radar transfer function, and this letter aims at dealing with this problem. First, an inequation is introduced to evaluate the highest order of range frequency terms whose space-variant coefficient has to be taken into account. Then, based on the method of series reversion, this letter proposes the extended NCS which can weaken the range dependence of the considered range frequency terms and achieve accurate range cell migration correction and range compression. Simulation results are presented to validate the proposed method.
Identification and Characterization of a Duck Enteritis Virus US3-Like Gene

Abstract Duck enteritis virus (DEV) causes substantial losses on duck farms; however, its molecular biology is poorly understood. Here, an open reading frame of a US3-like gene of DEV was identified from a DEV genomic library. Its existence was confirmed by cloning from DEV-infected duck embryo fibroblasts (DEFs) and DNA sequencing. The US3-like gene was then subcloned into a prokaryotic protein expression vector and expressed as a six-histidine–tagged fusion protein in Escherichia coli. The protein was purified and inoculated into rabbits for antiserum production. A primary antibody specific to the gene was successfully generated and used to detect the US3-like protein in DEV-infected duck cells. In vivo expression of the US3-like protein in DEV-infected DEFs was demonstrated with indirect immunofluorescence assay and regular fluorescence microscopy, whereas uninfected DEFs did not show any specific fluorescent staining. Furthermore, indirect immunofluorescence assay and confocal microscopy were used to study the time course and subcellular localization of the protein expression. The protein was found to be expressed as early as 2 hr postinfection, and its expression was increased by time at 4, 8, 12, and 24 hr postinfection. The protein was found to be localized mostly around the perinuclear area and in the cytosol, and also in the nucleus at later time points. In addition, a US3 protein phylogenetic tree was constructed and showed that the evolutionary relationship of DEV is close to the genus Mardivirus. In short, the DEV US3-like gene and its in vivo protein expression were found for the first time, and DEV classification and the gene's functions were suggested.
The wine consumer's behaviour in selected stores of Italian major retailing chains

Purpose – The principal aim of this article is to examine attitudes of Italian consumers in relation to wine, identifying specific types of wine buyers.Design/methodology/approach – A sample of 442 Italian wine consumers has been surveyed and three measurement instruments have been developed for grouping the observations by means of multivariate statistical analysis. The study then investigates both the consumer and product characteristics that significantly differentiate between the derived clusters of buyers and finally provides an external validity check.Findings – Although the study is exploratory in nature, there is evidence that four wine‐related consumer segments exist in our sample. These segments are habitual wine buyers, rational buyers, interested consumers, and professionals of promotions.Originality/value – For wine marketers, the results of this research clearly support the need for a targeted approach to their consumer market. The study identifies the principal consequences of the results i.
Differential power analysis attack considering decoupling capacitance effect

We examine the differential power analysis attack (DPA) on a pipelined FPGA implementation of AES when decoupling capacitors are in the circuit. In a recent work, researchers pointed out the use of the decoupling capacitors is inevitable for the encryption hardware operating at high clock frequencies. Also, use of the decoupling capacitance is advisable to protect the cryptographic algorithms against DPA attack since current is going to be delivered from the closest capacitor, not from the power supply. In this work we show that decoupling capacitors are not a protection method against DPA attack. In contrast, they are the local source for the charge delivery at high frequencies. Being able to observe the current flow on the pin renders the circuit open for attacks. As a result, integrated circuits (IC) working at high frequency range are still vulnerable to attack. We define the frequencies at which attack is successful. Our work gives the results when we attack on AES implementation by observing decoupling capacitor current flow of an FPGA operating up to 66 MHz clock frequency.
On the Extreme Positive Feedback Star-forming Mode from Massive and Compact Super Star Clusters

The force of gravity acting within the volume occupied by young, compact, and massive super star clusters is here shown to drive in situ all the matter deposited by winds and supernovae into several generations of star formation. These events are promoted by radiative cooling, which drains the thermal energy of the ejected gas causing its accumulation to then rapidly exceed the gravitational instability criterion. A detailed account of the integrated ionizing radiation and mechanical luminosity as a function of time is here shown to lead to a new stationary solution. In this, the mass deposition rate , instead of causing a wind as in the adiabatic solution, turns into a positive feedback star-forming mode equal to the star formation rate. Some of the implications of this extreme positive feedback mode are discussed.