Miracle-dz/UniFAR-FTUs huggingface dataset:
Year : 2010 CoopSC : A Cooperative Database Caching Architecture

Semantic caching is a technique used for optimizing the evaluation of database queries by caching results of old queries and using them when answering new queries. CoopSC is a cooperative database caching architecture, which extends the classic semantic caching approach by allowing clients to share their local caches in a cooperative matter. Cache entries of all clients are indexed in a distributed data structure constructed on top of a Peer-to-Peer (P2P) overlay network. This distributed index is used for determining those cache entries that can be used for answering a specific query. Thus, this approach decreases the response time of database queries and the amount of data sent by database server, because the server only answers those parts of queries that are not available in the cooperative cache. Abstract — Semantic caching is a technique used for optimizing the evaluation of database queries by caching results of old queries and using them when answering new queries. CoopSC is a cooperative database caching architecture, which extends the classic semantic caching approach by allowing clients to share their local caches in a cooperative matter. Cache entries of all clients are indexed in a distributed data structure constructed on top of a Peer-to-Peer (P2P) overlay network. This distributed index is used for determining those cache entries that can be used for answering a specific query. Thus, this approach decreases the response time of database queries and the amount of data sent by database server, because the server only answers those parts of queries that are not available in the cooperative cache.
The effect of dead-on-arrival and emergency department death classification on risk-adjusted performance in the American College of Surgeons Trauma Quality Improvement Program

BACKGROUND The American College of Surgeons’ Trauma Quality Improvement Program is focused on identifying variations in outcomes across trauma centers for the purposes of performance improvement. In previous analyses, patients who died in the emergency department were excluded. We investigated the effect of inclusion and exclusion of emergency department (ED) deaths (dead on arrival [DOA] and died in ED [DIE]) on analyses of overall risk-adjusted trauma center performance. METHODS Data for patients admitted to 65 Trauma Quality Improvement Program hospitals during the 2009 calendar year was used. A logistic regression model was developed to estimate risk-adjusted mortality. Trauma centers were then ranked based on their observed-to-expected (O/E) mortality ratio with 90% confidence intervals (CIs) and classified by outlier status: low outliers/high performers had a 90% CI for O/E mortality ratio of less than 1, and high outliers/low performers had a 90% CI for O/E mortality ratio of greater than 1. Changes in outlier status, rank, and quartile were examined with and without DOA and DIE patients included in the analyses to discern the impact of such exclusions on overall risk-adjusted center-specific performance. RESULTS Thirty-one trauma centers (48%) reported no DOA patients in 2009, while 6 centers (9%) reported more than 10. Of 224 patients, 14 (6.2%) had a documented time of death of more than 30 minutes after ED arrival despite being recorded as DOA. Forty-one trauma centers (63%) changed rank by three positions or less. Ten trauma centers changed their quartile ranking by a single quartile, but no centers were found to change quartile rank more than one quartile. Changes in outlier status occurred for 6 trauma centers (9%). CONCLUSION The relative frequency of patients classified as DOA varies greatly between trauma centers. Misclassification of patients as DOA occurs. Inclusion of ED deaths in risk-adjusted analysis of mortality results in a small but insignificant change in predicting the outcome results of a trauma center. This change is less than the rate of finding a center to be a high or low outlier by chance alone using the 90% CI. Inclusion of DOA and DIE patients in risk-adjusted analysis of mortality is appropriate and eliminates the bias introduced by exclusion of ED deaths owing to misuse of the DOA classification. LEVEL OF EVIDENCE Prognostic/epidemiologic study, level III.
Preliminary Results of Combining Thread-Level Speculation and Just-in-Time Compilation in Google’s V8

We present the first implementation of Thread-Level Speculation in combination with Just-in-time compilation. The implementation is done in Google’s V8, a well-known JavaScript engine, and evaluated on 15 popular web application executing on 2, 4, and 8 core computers. Our results show an average speedup of 2.9 on 4 cores, without any JavaScript code modifications. Further, we have found that the Just-in-time compilation time is significant, and that most functions are lazily compiled (approximately 80%) and that V8 contains features that are advantageous in Thread-Level Speculation.
An Empirical Comparison of Valuation Models for Interest Rate Derivatives

Interest rate derivatives are much more difficult to value than stock options. This paper discusses the basic approaches to price interest rate derivatives and presents the first comprehensive study of different models which can be used to manage the risk of interest rate derivatives. One and two factor models of the Heath / Jarrow / Morton type and inversion models of the Hull / White type are considered.
Assessing COTS software in a certifiable safety‐critical domain

Abstract. Commercial off‐the‐shelf (COTS) software solutions have become commonplace in many domains, including the military, because they can provide standardized functionality with more responsiveness, a shorter time‐to‐market and at lower costs than custom‐made solutions. In one domain, however, that of certifiable safety‐critical applications, COTS software has not been adopted. One particular type of certifiable safety‐critical domain, the civil air transport industry, is under pressure to reduce cost and time‐to‐market while simultaneously increasing safety. Therefore, the use of COTS software, rather than exclusive reliance on custom‐made software, would appear to be a solution worthy of investigation. This study examines the certifiability of COTS software, its technical feasibility in this environment, and the ability to achieve the expected responsiveness, time‐to‐market and cost benefits. A detailed evaluation of COTS software and domain‐specific certification requirements is used to demonstrate that the certification of COTS‐based systems is possible. A prototype COTS‐based system (built upon a number of COTS components) is created to illustrate the technical feasibility of such a system in the civil air transport domain. Expected benefits from COTS solutions are evaluated both by examining process artefacts from the development of the COTS‐based system and by comparing this development process with the domain's traditional custom‐development process.
Prejudice matters: understanding the reactions of Whites to affirmative action programs targeted to benefit Blacks.

The authors examined, in 2 studies, the effects of equal employment opportunity/affirmative action (EEO/AA) policies on Whites' job-related attitudes. First, in an experiment, White prospective job recruits, as expected, rated a potential employer whose EEO/AA policies were framed as targeted to benefit Blacks as less attractive than a potential employer whose EEO/AA policies were framed more generally. Second. the results of a field study showed that prejudice against Blacks moderated the relationship between Whites' perceptions that their organization's EEO/AA policies were targeted to benefit Blacks and their satisfaction with promotion opportunities. Specifically, among prejudiced Whites, this relationship was negative and considerable in size (r = -.39. p < .01); whereas, among nonprejudiced Whites, it was negligible (r = -.04, ns). The implications of our findings for the study of prejudice in organizations are discussed.
Wound metastasis after laparoscopy with different insufflation gases.

BACKGROUND There is growing evidence that laparoscopy for malignancy is associated with an increased incidence of metastasis to port sites. This study investigated the effect of different insufflation gases on port-site metastasis after laparoscopy in an established animal model. METHODS Forty-eight Dark Agouti rats with an established adenocarcinoma in the left flank underwent laparoscopic intraperitoneal tumor laceration. The gas used for insufflation was one of the following (12 rats in each group): (1) CO2, (2) N2O, (3) helium, or (4) air. Rats were killed 7 days after the procedure, and the port sites were examined for the presence of tumor metastasis. RESULTS Tumor involvement of port sites was significantly less likely after helium insufflation than in the other groups (p < 0.0001). There was no significant difference between the air, CO2, and N2O groups. CONCLUSIONS This study suggests that the development of metastases in port sites after laparoscopy may be influenced in part by the choice of insufflation gas used to create the pneumoperitoneum. In particular, helium was associated with a reduced rate of metastases.
Common origin of the human synovial sarcoma associated SS18 and SS18L1 gene loci

The highly conserved synovial sarcoma associated protein SS18 is thought to act as a transcriptional co-activator through interactions with various proteins involved in (epigenetic) gene regulation. The SS18 SNH domain appears to act as a major interface for these protein-protein interactions. Previously, we used this SNH domain to identify SS18 paralogs (SS18L1 and SS18L2) and orthologs in various species. The functional significance of these SS18-like proteins is embodied by the observations that SS18L1 and SS18L2 can replace SS18 in its various protein-protein interactions, and that SS18L1 may act as a fusion partner of SSX in synovial sarcoma. In the current study, we performed a comprehensive comparison of SNH-containing loci in several distinct species. By doing so, we found that the vertebrate SS18 and SS18L1 genes map within co-linear DNA segments that may have evolved through a relatively recent genomic duplication event. An additional phylogenetic study indicated that the more divergent SS18L2 gene is most likely derived from an earlier gene duplication event, again in the vertebrate lineage.
Evolving Order? Inter-Organizational Relations in the Organizational Field of Food Security Governance in Côte d’Ivoire

Abstract Global food security governance is fraught with fragmentation, overlap and complexity. While calls for coordination and coherence abound, establishing an inter-organizational order at this level seems to remain difficult. While the emphasis in the literature has so far been on the global level, we know less about dynamics of inter-organizational relations in food security governance at the country level, and empirical studies are lacking. It is this research gap the article seeks to address by posing the following research question: In how far does inter-organizational order develop in the organizational field of food security governance at the country level? Theoretically and conceptually, the article draws on sociological institutionalism, and on work on inter-organizational relations. Empirically, the article conducts an exploratory case study of the organizational field of food security governance in Côte d’Ivoire, building on a qualitative content analysis of organizational documents covering a period from 2003 to 2016 and semi-structured interviews with staff of international organizations from 2016. The article demonstrates that not all of the developments attributed to food security governance at the global level play out in the same way at the country level. Rather, in the case of Côte d’Ivoire there are signs for a certain degree of coherence between IOs in the field of food security governance and even for an – albeit limited – division of labour. However, this only holds for specific dimensions of the inter-organizational order and appears to be subject to continuous contestation and reinterpretation under the surface.
Adaptive Tracking Control of nonholonomic Systems Based on Feedback Error Learning

In this paper, we present an adaptive feedback error learning (AFEL) control scheme that are suitable for a class of nonholonomic wheeled mobile robots with uncertainties. The proposed algorithm employs nonlinear function approximation with automatic growth of the neural network (NN) learning according to the nonlinearities and the working domain of the tracking control system. The unknown function in dynamical system is approximated by training nonlinear NN models, and, imperfect approximation errors of NNs are relaxed by designing parallel robust term. Lyapunov synthesis is proposed for AFEL control design with guaranteed stability. Inspired by composite adaptive control scheme, the proposed adaptive control algorithm employs both closed-loop tracking errors and estimation errors to optimize the parameters by NN online weight tuning algorithms, which guarantee small tracking errors and no loss of stability in robot motion with bounded input signals. We demonstrate superior tracking results using the proposed AFEL control method in various Matlab simulations.
Decoding willingness of Indian consumers to pay a premium on green products

Purpose The purpose of this paper is to identify the relevant antecedents of willingness of Indian consumers to pay a premium for green products and empirically validate the relationship between these antecedents and willingness to pay (WTP). Design/methodology/approach Data were generated from 515 students enroled in various educational institutions approved by the All India Council for Technical Education and located in New Delhi and National Capital Region region of India. A combination of researcher-controlled and systematic sampling techniques was employed for the purpose of identifying the sample. Structural equation modelling was used to analyse the data using AMOS 20.0. Findings The study revealed that attitude towards green products (ATGP) has a significant and positive influence on WTP. Additionally, collectivism and environmental concern emerged as predictors of ATGP. Practical implications Marketing practitioners are expected to get deeper insights into reasons that contribute to the formation of positive attitude among Indian consumers towards green products. This understanding may greatly assist proactive marketers in developing appropriate strategies to increase the propensity of WTP a premium for such products. Originality/value The study is pioneering in the sense that the construct WTP for green products had relatively been less explored in the Indian context. The construct WTP is important for Indian consuming class which is dominated by middle and lower middle income groups for whom spending extra from their regular expenditure is a critical and sensitive issue.
The Anaphase Promoting Complex Regulates Yeast Lifespan and rDNA Stability by Targeting Fob1 for Degradation

Genomic stability, stress response, and nutrient signaling all play critical, evolutionarily conserved roles in lifespan determination. However, the molecular mechanisms coordinating these processes with longevity remain unresolved. Here we investigate the involvement of the yeast anaphase promoting complex (APC) in longevity. The APC governs passage through M and G1 via ubiquitin-dependent targeting of substrate proteins and is associated with cancer and premature aging when defective. Our two-hybrid screen utilizing Apc5 as bait recovered the lifespan determinant Fob1 as prey. Fob1 is unstable specifically in G1, cycles throughout the cell cycle in a manner similar to Clb2 (an APC target), and is stabilized in APC (apc5CA) and proteasome (rpn10∆) mutants. Deletion of FOB1 increased replicative lifespan (RLS) in wild type (WT), apc5CA, and apc10∆ cells, and suppressed apc5CA cell cycle progression and rDNA recombination defects. Alternatively, increased FOB1 expression decreased RLS in WT cells, but did not reduce the already short apc5CA RLS, suggesting an epistatic interaction between apc5CA and fob1∆. Mutation to a putative L-Box (Fob1E420V), a Destruction Box-like motif, abolished Fob1 modifications, stabilized the protein, and increased rDNA recombination. Our work provides a mechanistic role played by the APC to promote replicative longevity and genomic stability in yeast.
Non-aqueous titrimetric assay of doxycycline hyclate in pharmaceutical preparations.

Doxycycline is a member of the tetracycline derivation and has a wide range of antibacterial activity. Two simple, cost-effective, accurate, and precise direct titrimetric methods to the detn. of doxycycline hyclate (DOX) in pharmaceutical prepns. were developed and validated. The methods are based on the titrn. of DOX with 0.01 N acetous perchloric acid in the presence of mercuric acetate in glacial acetic acid using either crystal violet as indicator in visual end point detection (method A) or by combined glass electrode in potentiometric end point detection (method B). The methods were applicable over the range of 4.0 - 40 mg DOX. The validation of the methods yielded good results that included precision (RSD < 3% for intra- and inter-day precision), and accuracy (RE â‰¤ 2.68%). It was also found that the excipients in the com. tablet prepn. did not interfere with the assay and the results were compared with the official HPLC method. [on SciFinder(R)]
Does size matter? The effects of enterprise size on the perception of benefits and risks of open innovation projects

This article presents an exploratory study investigating the influence of an enterprise’s size on its perception and assessment of the benefits and risks expected from participating in open innovation projects. For this purpose an online survey was conducted in Germany, Austria and Switzerland. The result of this paper is empirical evidence showing how the size of an enterprise affects its perception of potential benefits and risks expected within the context of open innovation project participation. Furthermore, the identified effects are discussed against the theory. Existing theory regarding the benefits and risks of open innovation is expanded by 1) finding that they are perceived mostly independently of enterprise size, 2) confirming their practical relevance, and 3) enabling a finer distinction between their degrees of relevance for small, medium, and large enterprises.
Designing Pervasive Information Systems: A Fashion Retail Case Study

We expand the design theory for cyber physical systems by introducing the notion of mutability of legacy components. Mutability refers to the extent components of the legacy system can be modified to facilitate better integration with the information system components. In particular, immutable components must remain untouched during the introduction of a cyber physical system. We explore our propositions considering a design showcase for an automated checkout system for retail fashion environments. The artifact consists of an RFID sensor infrastructure and data-driven software components that process the low-level sensor data to provide seamless checkout functionality. The system is evaluated by means of a comprehensive trial in a presentative retail laboratory.
Hybrid Feature Factored System for Scoring Extracted Passage Relevance in Regulatory Filings

We report in this paper our contribution to the FEIII 2017 challenge addressing relevance ranking of passages extracted from 10-K and 10-Q regulatory filings. We leveraged our previous work on document structure and content analysis for regulatory filings to train hybrid text analytics and decision making models. We designed and trained several layers of classifiers fed with linguistic and semantic features to improve relevance prediction. We discuss in this paper our experiments and results on the competition data set.
Image smoothing based on local image models

On the basis of an algorithm which identifies the neighborhood of a pixel as constant, oriented, or irregular based on the spatial relationship among the pixels inside this neighborhood, the use of different smoothing schemes according to the neighborhood surrounding each pixel is proposed. This approach is applied to images corrupted with additive Gaussian noise and impulse speckle noise. The flat regions of an image are smoothed sufficiently, while linear structures are enhanced. <<ETX>>
A real time emotional interaction between EEG brain signals and robot

In this paper, emotion recognition using frontal electroencephalogram (EEG) asymmetry signals is presented. A total of four channels are used in representing EEG frontal asymmetry, consisting of the left and right hemisphere of the brain. Arousal and valence for two-dimensional emotion models are used in classifying four basic emotions; happy, sad, angry, and relaxed. The mirror neuron system (MNS) for emotion elicitation is utilized in finding correlation between participant's emotion rating and EEG data. This is achieved by showing images and music to each participant. These images are used to elicit emotions in applying the imitation concept. In addition, an emotion recognition method based on a combination of two algorithms, fractal dimension for feature extraction and multidimensional direct information on finding correlation between left and right EEG frontal asymmetry is proposed. Good performances are achieved from the combination and rating process, where it can be utilized to indicate correlation between participants rating and EEG recorded data. The final results of the EEG recorded data are represented as robot emotions. Therefore, the main contribution is to create a real-time emotional interaction based on the analyzed EEG recorded data.
Chronic Exposure to Ammonia Alters Pathways Modulating Phosphorylation of Microtubule‐Associated Protein 2 in Cerebellar Neurons in Culture

Abstract : Hyperammonemia is considered the main cause for the neurological alterations found in hepatic failure. However, the mechanisms by which high ammonia levels impair cerebral function are not well understood. It has been shown that chronic hyperammonemia impairs signal transduction pathways associated with NMDA receptors and also alters phosphorylation of some neuronal proteins. The aim of the present work was to analyze the effects of chronic exposure to ammonia on phosphorylation of microtubule‐associated protein 2 (MAP‐2) in intact neurons in culture and to assess whether modulation of MAP‐2 phosphorylation by glutamate receptor‐associated transduction pathways is altered in neurons chronically exposed to ammonia. It is shown that chronic exposure to ammonia increases basal phosphorylation of MAP‐2 by ~70%. This effect seems to be due to a decreased tonic activation of NMDA receptors and of calcineurin. Chronic exposure to ammonia also alters the modulation of MAP‐2 phosphorylation by NMDA receptors and metabotropic glutamate receptors. In neurons exposed to ammonia, treatment with NMDA for 30 min induced a significant decrease in phosphorylation of MAP‐2. Activation of metabotropic glutamate receptors with (1S,3R)‐1‐aminocyclopentane‐1,3‐dicarboxylic acid significantly increased phosphorylation of MAP‐2 in control neurons, whereas in neurons exposed to ammonia the response was the opposite, with 1‐aminocyclopentane‐1,3‐dicarboxylic acid inducing a dephosphorylation of MAP‐2. These results indicate that ammonia alters significantly signal transduction pathways associated with different types of glutamate receptors. This would lead therefore to significant alterations in glutamatergic neurotransmission, which would contribute to the neurological alterations found in hyperammonemia and in hepatic encephalopathy.