Miracle-dz/UniFAR-FTUs huggingface dataset:
KNOWLEDGE MANAGEMENT FOR MAINTENANCE ACTIVITIES IN THE MANUFACTURING SECTOR

Maintenance is an indispensable part of the business process and plays an important role in an organisation’s success and survival. The main purpose of maintenance is to ensure equipment functions at its original optimal level. Thus, the knowledge and skills of operators are crucial and in demand. This paper presents a knowledge management of maintenance activities transfer method. Knowledge management is a process that a company cannot avoid, because it is a step in providing the necessary information for business performance measurements. Based on the example of a knowledge management system for a consultant company, we propose a knowledge repository or warehouse for maintenance activities that consists of four elements: best practice, databases, discussion forums and assessment tools. Each element has its own role and contribution towards better maintenance activities. Therefore, knowledge management has a deep relationship with performance evaluation or measurement.
Development of ethanol tolerance in Clostridium thermocellum: effect of growth temperature

The growth of Clostridium thermocellum ATCC 27405 and of C9, an ethanol-resistant mutant of this strain, at different ethanol concentrations and temperatures was characterized. After ethanol addition, cultures continued to grow for 1 to 2 h at rates similar to those observed before ethanol was added and then entered a period of growth arrest, the duration of which was a function of the age of inocula. After this period, cultures grew at an exponential rate that was a function of ethanol concentration. The wild-type strain showed a higher energy of activation for growth than the ethanol-tolerant derivative. The optimum growth temperature of the wild type decreased as the concentration of the ethanol challenge increased, whereas the optimum growth temperature for C9 remained constant. The results are discussed in terms of what is known about the effects of ethanol and temperature on membrane composition and fluidity.
Q-RRBS: a quantitative reduced representation bisulfite sequencing method for single-cell methylome analyses

Reduced representation bisulfite sequencing (RRBS) is a powerful method of DNA methylome profiling that can be applied to single cells. However, no previous report has described how PCR-based duplication-induced artifacts affect the accuracy of this method when measuring DNA methylation levels. For quantifying the effects of duplication-induced artifacts on methylome profiling when using ultra-trace amounts of starting material, we developed a novel method, namely quantitative RRBS (Q-RRBS), in which PCR-induced duplication is excluded through the use of unique molecular identifiers (UMIs). By performing Q-RRBS on varying amounts of starting material, we determined that duplication-induced artifacts were more severe when small quantities of the starting material were used. However, through using the UMIs, we successfully eliminated these artifacts. In addition, Q-RRBS could accurately detect allele-specific methylation in absence of allele-specific genetic variants. Our results demonstrate that Q-RRBS is an optimal strategy for DNA methylation profiling of single cells or samples containing ultra-trace amounts of cells.
Psychometric properties of Liverpool Stoicism Scale (LSS) in a cohort of patients with resected cancer in adjuvant treatment

espanolEl estoicismo se ha utilizado para describir una amplia gama de comportamientos frente a la enfermedad que van desde el silencio a la resistencia a la adversidad. Este estudio tiene dos objetivos: 1) analizar las propiedades psicometricas de la version espanola del LSS; 2) evaluar la relacion entre estoicismo, genero, edad y el modelo de los cinco grandes factores de personalidad. NEOcoping es un estudio prospectivo, multicentrico, observacional, no-intervencionista. Los pacientes fueron reclutados consecutivamente en 13 hospitales universitarios de Espana. Se aplico la Liverpool Stoicism Scale (LSS) y el Big Five Inventory (BFI-10). Participaron 443 pacientes (250 mujeres) con una edad media de 59,8 anos (SD =12,3). El cancer de colon y mama fueron los mas frecuentes. A nivel de escala total, la puntuacion media de la LSS fue inferior a la muestra Britanica. La estructura propuesta en cuatro factores proporciona un buen ajuste a los datos, y las puntuaciones en las escalas derivadas presentan fiabilidades aceptables. El rasgo de personalidad de introversion fue capaz de predecir el 4,1% de la variancia de estoicismo (p EnglishStoicism has been used to describe a wide range of behaviors in the face of disease that go from silence, resistance to the adversity, or ‘to make the best of a bad disease’. This study pursued two objectives: 1) analyze the psychometric properties of the Spanish version of the LSS; 2) assess the relation between stoicism and gender, age, and the five-factor personality model. NEOcoping is a prospective, multicenter, observational, non-interventionist study. Patients were recruited consecutively at thirteen Spanish teaching hospitals. The following scales were administered: Liverpool Stoicism Scale (LSS) and Big Five Inventory (BFI-10). A total of 443 patients (250 females) with a mean age of 59.8 years (SD =12.3) were enrolled. Colon cancer was the most common, followed by breast cancer. At the total-scale level, mean LSS was lower than the originally reported British sample. The four-factor structure fitted the data well, had a clear interpretation, and the derived scales showed acceptable reliabilities. The personality trait of introversion predicted 4.1% of the variance of stoicism (p
Influences of the tropical Indian and Atlantic Oceans on the predictability of ENSO

The El Niño Southern Oscillation (ENSO) is the leading mode of climate variability and predictable on interannual time scales. Recent studies suggest that the tropical Indian and Atlantic Oceans influence the dynamics and predictability of ENSO. Here we investigate these effects in a hybrid coupled model consisting of a full complexity atmospheric general circulation model (GCM) coupled to a strongly simplified linear 2‐dimensional ENSO recharge oscillator ocean model. We find that the tropical Indian and Atlantic Oceans have distinct effects on the dynamics and predictability. The decoupling of the tropical Indian Ocean has a strong impact onto ENSO dynamics, but the initial conditions of it have only a small impact on the ENSO predictability. In contrast, initial conditions of the tropical Atlantic have a stronger impact on the predictability of ENSO, but the decoupling of the tropical Atlantic has almost no effect on the ENSO dynamics.
Bank Ownership and Capital Buffers: How Internal Control is Affected by External Governance

Abstract Using a sample of almost 300 European banks, we show that the concentration of ownership leads to larger capital buffers, consistent with theories of interest alignment and the charter value theory. Mixed empirical findings of previous literature suggest that external factors may affect the disciplinary role of controlling owners. In this paper, we demonstrate that the stabilizing impact of concentrated ownership is weaker when the level of regulatory discipline is higher. We also observe a weaker stabilizing impact when the level of market discipline is higher, while this effect seems to be less robust. Moreover, we find evidence for the too-big-to-fail phenomenon, since the stabilizing impact of ownership concentration on capital buffers is significantly weaker for systemically important institutions. Our findings indicate that bank owners are aware of the risk of losing charter value when external monitoring is lower and underline that internal governance of banks should not be discussed in isolation from external governance factors.
Participatory and collaborative modelling key to sustainable and inclusive development : strengthening stakeholder ownership for informed and participatory water resources management

Safe access to water is essential for sustainable development. Building resilience towards disaster risks and ensuring water availability by balancing the many competing uses and users of water, while maintaining healthy and diverse ecosystems, are critical elements to ultimately deliver water security. In this Ph.D. thesis, participatory and collaborative modelling is presented as a means towards sustainable development,as it supports informed decision-making and inclusive development. How to develop and use computer-based simulation models is analysed following a participatory or collaborative modelling approach for managing water resources, so their use can be enhanced, and the ownership of the development strengthened. Four methods are presented to engage stakeholders in the development and use of computer-based simulation models. These approaches are tested in nine study cases, from which this thesis focuses on five of them. The covered themes and countries include river basin planning in Indonesia, water quality management in Turkey and Indonesia, adaptive planning in Bangladesh, and flood risk management in Tanzania. Results of the research show that the use of participatory and collaborative modelling makes the modelling process more efficient. Together, modellers and stakeholders share learning, build consensus, have a sense of ownership of the models, tools and solutions developed and trust in the decision-making process.
An Empirical Examination of an Agile Contingent Project/Method Fit Model

: While research has demonstrated positive productivity and quality gains from using agile software development methods (SDMs), some experts argue that no single SDM suits every project context. We lack empirical evidence about the project contextual factors that influence when one should use these methods. Research suggests several factors to explain agile method appropriateness; however, generalizable empirical evidence supporting these suggestions is weak. To address this need, we used contingency theory and the information processing model to develop the agile contingent project/method fit model. Subsequently, we used the model to analyze the influence of project contextual factors and agile practices on software development professionals’ perceptions regarding agile SDM appropriateness. We tested the model using survey data collected from 122 systems development professionals who provided information regarding: 1) contextual factors surrounding a recent agile development project, 2) agile practices applied during the course of that project, and 3) perceptions regarding the relative fit (appropriateness) of the agile method used. Linear regression identified several significant relationships between project contextual factors, agile practices, and respondents’ relative fit perceptions.
Elimination of person names in spoken documents for privacy protection

There is an increasing use of sensor networks capable of sensing multimedia data including audio data. Unfortunately, public use of these is not allowed because they contain crucial privacy information such as person and location names. Person name extraction (PNE), which is a widely investigated research topic, is an effective technique to resolve this problem. However, there is an important difference between traditional PNE and PNE for privacy protection: traditional PNE often misses out-of-vocabulary (OOV) person names that do not occur in a training corpus, and PNE for privacy protection must cover OOV person names because of the demand for privacy protection. To resolve the issue of PNE for privacy protection, this study proposes a method consisting of two stages: the first stage is speech recognition using a language model modified to over-extract person names including OOV person names, and the second stage is filtering over-extracted person names using an SVM (Support Vector Machine). The experiments show that our method is effective in detecting / eliminating person names, and listening tests also show that the performance of our method in removing person names is promising.
An Explanation of Human Capital Disclosure from the Resource Based Perspective

Though the importance of human capital (HC) in firm value creation is firmly established in the literature the level of emphasis placed on human capital disclosure (HCD) by preparers of financial statements and sell-side analysts is minimal. The purpose of this paper is to address this dilemma by critically analysing the conceptualisation of human capital in disclosure literature and introduce a more germane explanation.
Design of diversity antenna array for GALILEO/GPS receivers

This paper presents a preliminary study on a dual-element diversity antenna array for the GALILEO/GPS receivers to overcome the link difficulty in a multipath environment. The proposed design of the dual-element pattern diversity antenna consists of two helical antennas operating at L1 band. Though the helix exhibits a linear polarisation, it is noticed that the RHCP is not strictly required for GPS link in a highly scattered environment. It is calculated that the proposed dual-element antenna array can obtain a diversity gain of around 7 dB, which offers a substantial improvement to the signal link in the GALILEO/GPS system.
Resource orchestration to improve communication with customers: "case study: MSME footwear in East Java"

: This study aims to discuss the orchestration of resources in MSME in accordance with the implementation of ISO 9001 standards and the improvement of product competitiveness. By using case study research approach at MSME footwear in East Java, the results obtained are the information on how the company is orchestrating its resources from the early stages toward the growth stage by means of the certification program of ISO 9001. In the early stages, the company owner has lots of activity of routine work and is only reactive to the problems occurred, but after applying ISO 9001, the owner finds that the management of the company is more coordinated, and controlled. Besides, the company has more activities to develop including establishing communication and maintaining relationships with the customers.
New Methods of Assessing Damage from Environmental Pollution

The process of developing methods for the economic assessment of environmental damage is subject to the requirements of world society, the policies of leading countries. The authors disclosed the existing approaches to the economic assessment of damage and showed the need for their development. The need for ecological rehabilitation of territories contaminated in past periods led to the creation and practical use of methods for the economic evaluation of past damage. The authors proposed a new approach to the economic assessment of past damage, which takes into account economic and assimilation factors. In addition, the article proposes a method for the economic evaluation of damage from emergencies, taking into account the cascading effects of the damage caused to the environment, the economy, the society and natural resources. The proposed method allows considering the indirect damages transmitted in the selected directions of the assessment taking into account the time factor.
A New Measure of the Quality of Tourism Product

Tourism product competitiveness depends on innovation and quality levels and on its capacity to reflect the destinations’ identity. For these reasons and inspired by the EC and UNWTO recommendations we developed a tourism quality scale, adapted to the Portuguese reality, which is supported by 5 subscales. This paper focuses on the validation of the tourism product subscale, which was tested among local public stakeholders, specifically Portuguese municipalities. Exploratory and confirmatory factor analyses were performed and three factors supported quality measurement regarding the tourism product: (1) services; (2) resources and attractions; and (3) accessibilities and infrastructures. Results demonstrate there are theoretical and practical implications and the conclusions provide useful insights for future research.
Epithelial Membrane Protein-2 (EMP2) Activates Src Protein and Is a Novel Therapeutic Target for Glioblastoma*

Background: EMP2 is a tetraspan protein linked with aggressive disease. Results: EMP2 correlates with activated Src in patients with GBM. Using intracranial mouse models, EMP2 promotes tumor cell invasiveness. Antibodies to EMP2 reduce GBM tumor load. Conclusion: EMP2 is a novel therapeutic target in GBM. Significance: The clinical outcome for patients with GBM remains poor, and thus new targeted therapies are needed. Despite recent advances in molecular classification, surgery, radiotherapy, and targeted therapies, the clinical outcome of patients with malignant brain tumors remains extremely poor. In this study, we have identified the tetraspan protein epithelial membrane protein-2 (EMP2) as a potential target for glioblastoma (GBM) killing. EMP2 had low or undetectable expression in normal brain but was highly expressed in GBM as 95% of patients showed some expression of the protein. In GBM cells, EMP2 enhanced tumor growth in vivo in part by up-regulating αvβ3 integrin surface expression, activating focal adhesion kinase and Src kinases, and promoting cell migration and invasion. Consistent with these findings, EMP2 expression significantly correlated with activated Src kinase in patient samples and promoted tumor cell invasion using intracranial mouse models. As a proof of principle to determine whether EMP2 could serve as a target for therapy, cells were treated using specific anti-EMP2 antibody reagents. These reagents were effective in killing GBM cells in vitro and in reducing tumor load in subcutaneous mouse models. These results support the role of EMP2 in the pathogenesis of GBM and suggest that anti-EMP2 treatment may be a novel therapeutic treatment.
The Impact of a Mandated Trauma Center Alcohol Intervention on Readmission and Cost per Readmission in Arizona

Background:Persons appearing in trauma centers have a higher prevalence of unhealthy alcohol use than the general population. Screening and brief intervention (SBI) is designed to moderate drinking levels and avoid costly future readmissions, but few studies have examined the impact of SBI on hospital readmissions and health care costs in a trauma population. Research Design:This study uses comparative interrupted time-series and the Arizona State Inpatient Database to estimate the effect of the American College of Surgeons Committee on Trauma SBI mandate on the probability of readmission and cost per readmission in Arizona trauma centers. We compare individuals with and without an alcohol diagnosis code before and after the mandate was implemented. Results:The mandate resulted in a 2.2 percentage point reduction (44%) in the probability of readmission. Total health care and readmission costs were not affected by the mandate. Conclusions:The estimates are consistent with a differential effect of SBI: SBI reduces readmissions among those who present with a less serious alcohol-related problem. Persons with more serious alcohol problems are less likely to respond to SBI. These higher risk individuals likely have a higher cost, which may explain the lack of change in readmission costs. Our study is a macrolevel intent-to-treat analysis of SBI’s impact that corroborates the potential of SBI implied by efficacy studies in trauma centers and other settings. This study provides a framework for future research involving more states and health systems and evaluating other SBI policies.
RESEARCH AND DEVELOPMENT OF GENETIC ENGINEERING IN MEDICINE AND AGRICULTURE IN THE UNITED STATES OF AMERICA

The status of research, development and application of genetic technology in the US has been reflected through efforts and accomplishments in numerous fields including research, medicine, industrial biotechnology and agriculture in the past decades. In the area of medicine, the field of therapeutic purposes on human is the pioneer, in which gene therapy is attempted to carry out in various clinical trials. Diagnostic applications of human diseases which focus primarily on infectious diseases, cancer, pharmacogenomics and screening for inherited diseases by using molecular techniques related to PCR, next generation sequencing are followed. In addition, preparatory studies on human cells utilizing CRISPR/Cas9 genome editing technology have been undertaken in hopes of finding new treatments for cancer and rare form of eye disorder. In the field of agriculture, many large companies in the US have been developing varieties of genetically modified crops with traits of herbicide tolerance, insect resistance, drought resistance and nutrition enhancement. Among the biotech crops, proportion of planted acres of genetically engineered soybean, corn and cotton were increased rapidly and forecasted to expand in the coming years. Studies on generating genetically modified animals and fisheries have also been concentrated in order to not only resist diseases, enhance nutrition, but also provide pharmaceutical compounds. Application of new gene editing techniques such as CRISPR/Cas9 on plants and animals help biotech products have more opportunities to be approved for commercial sale in the US market. In general, although the research and application of genetic engineering in the US has outstripped worldwide, numerous obstacles are still encountered due to serious ethical regulations and controversy regarding to human health and environment. The US government continues to establish suitable policies and invest in science and technology to improve the quality of human life.
Indexation des documents multilingues d'actualité incluant l'arabe : équivalence interlangues et gestion des connaissances chez les indexeurs

Le thesaurus pourrait etre une solution pour l'indexation des documents multilingues, le role de cet outil etant de limiter les incoherences du vocabulaire en harmonisant les descripteurs choisis. Or une etude menee sur le terrain a demontre que les problemes engendres par la recherche d'equivalence de langue a langue ne sont pas veritablement resolus malgre l'usage de cet outil. La documentation propose, a travers les normes et ouvrages de construction des thesaurus multilingues, des solutions inspirees de la terminologie. Celle-ci presente des techniques differentes notamment par une approche comparee des termes et des notions pour resoudre ces problemes de variations. Cependant, la difficulte provient du fait que les langues et les cultures decoupent le reel de maniere differente. Le caractere semiotique du processus d'indexation nous amene a explorer la sphere cognitive. La question est alors de savoir si l'indexeur s'appuie plus sur ses propres connaissances pour resoudre le probleme de recherche d'equivalence ou sur des connaissances externes. Nous avons elabore un protocole d'experimentation pour le contexte multilingue en nous basant sur les quelques travaux realises pour l'etude du processus cognitif en indexation monolingue. L'experimentation a montre que l'indexeur s'appuie sur les outils disponibles mais egalement sur ses connaissances. Nous avons ainsi pu etablir un schema du processus cognitif qui permet de voir le cheminement de l'indexeur lors de son activite d'indexation en contexte multilingue. Ces strategies fournissent des informations utiles pour elaborer des outils multilingue pertinente pour la gestion des connaissances.