Miracle-dz/UniFAR-FTUs huggingface dataset:
Overlapping kernel-based Community Detection with node attributes

Community Detection is a fundamental task in the field of Social Network Analysis, extensively studied in literature. Recently, some approaches have been proposed to detect communities distinguishing their members between kernel that represents opinion leaders, and auxiliary who are not leaders but are linked to them. However, these approaches suffer from two important limitations: first, they cannot identify overlapping communities, which are often found in social networks (users are likely to belong to multiple groups simultaneously); second, they cannot deal with node attributes, which can provide important information related to community affiliation. In this paper we propose a method to improve a well-known kernel-based approach named Greedy-WeBA (Wang et al., 2011) and overcome these limitations. We perform a comparative analysis on three social network datasets, Wikipedia, Twitter and Facebook, showing that modeling overlapping communities and considering node attributes strongly improves the ability of detecting real social network communities.
Enumeration of MOLS of small order

We report the results of a computer investigation of sets of mutually orthogonal latin squares (MOLS) of small order. For $n\le9$ we 1. Determine the number of orthogonal mates for each species of latin square of order $n$. 2. Calculate the proportion of latin squares of order $n$ that have an orthogonal mate, and the expected number of mates when a square is chosen uniformly at random. 3. Classify all sets of MOLS of order $n$ up to various different notions of equivalence. We also provide a triple of latin squares of order 10 that is the closest to being a set of MOLS so far found.
Design of a nonblocking shared-memory copy network for ATM

A new nonblocking copy network is presented, for use in an ATM switch supporting BISDN, with a shared-memory input buffer. Blocked cells from any switch input are stored in a single shared input buffer. The copy network consists of three Omega networks and shared-memory queues. The design is scalable for large numbers of inputs due to a low hardware complexity, O(N log/sub 2/ N), and distributed operation and control. It is shown by simulation results that a switch incorporating the shared-memory copy network has increased throughput and lower buffer requirements to maintain low packet loss probability when compared to a switch with a discrete buffer copy network. <<ETX>>
CSSDev: Refactoring Duplication in Cascading Style Sheets

Cascading Style Sheets (CSS) is a widely-used language for defining the presentation of structured documents and user interfaces. Despite its popularity, CSS still lacks adequate tool support for everyday maintenance tasks, such as debugging and refactoring. In this paper, we present CSSDEV, a tool suite for analyzing CSS code to detect refactoring opportunities. (https://youtu.be/lu3oITi1XrQ).
Synthesis and Energy Transfer Efficiency of FRET Terminators Derived from Different Linkers

Abstract A number of different energy transfer dye labeled-cassettes were synthesized using aminoacid based trifunctional linkers and coupled to the propargylamino-substituted dideoxynucleoside-5′-triphosphates (ddNTPs). These terminators were evaluated for their energy transfer efficiency and DNA sequencing potential using thermostable DNA polymerase.
Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma

RASSF2 can bind directly to K‐Ras and function as a negative effector of Ras protein. RASSF2A is the only isoform of RASSF2 that contains CpG islands in its promoter and it has been reported to be inactivated by its promoter methylation in several human cancers. In the present study, we investigated the correlation of RASSF2A expression with its promoter methylation in nasopharyngeal carcinoma (NPC). Expression of RASSF2A was down‐regulated in 80% (4/5) of NPC cell lines. Decreased RASSF2A expression was also observed in NPC primary tumors compared with normal nasopharyngeal epithelia. Promoter methylation of RASSF2A could be detected in all the RASSF2A‐silenced cell lines (4/5) of the NPC cell lines and 50.9% (27/53) of primary tumors, but not in any of the normal epithelia. RASSF2A‐methylated cases showed a significantly lower level of RASSF2A expression than unmethylated cases. Loss of RASSF2A expression can be greatly restored by the methyltransferase inhibitor 5‐aza‐dC in NPC cell lines. In addition, patients with methylated RASSF2A presented a higher frequency of lymph node metastasis (p < 0.05). Ectopic expression of RASSF2A in RASSF2A‐silenced and ‐methylated NPC cell line CNE2 shows that RASSF2A could inhibit cell cycle progression, colony formation and cell migration, which provided further evidence that RASSF2A is a candidate tumor suppressor gene. In conclusion, RASSF2A, a candidate tumor suppressor gene (TSG), is frequently inactivated by its promoter methylation and this aberrant methylation correlates with lymph node metastasis in NPC. © 2006 Wiley‐Liss, Inc.
An Analysis of Factors Affecting the Intention of students to Using E-learning through virtual education Case Study: Virtual Faculty Students in University of Isfahan

The Internet has dramatically affected the deployment of virtual education. Virtual education is a term that encompasses online education through internet or electronic learning (E- learning). E-learning includes all learning methods which use new technologies. In most cases, e- learning refers to using computer networks or the internet to educate people. This study analyzes the factors that influence students' intention to use e-learning through the internet, and its population is virtual faculty students in University of Isfahan who have completed questionnaires either by their presence or through the internet (electronic questionnaires). This study's model includes five factors: social influence, facilitating conditions and e-learning motivation which have been used in previous studies to evaluate the students' intention to using e-learning; system quality and perceived benefits also are two factors that have been added to them. Spss 19 and Amos 18 software was used for data analysis. Results indicate the influence of perceived benefits and motivation and the ineffectiveness of facilitating conditions on the intention to use virtual education. Likewise, it was indicated that system quality influences the perceived benefits while, social influence are not effective. Finally, some recommendations are presented for the development of electronic government and citizen and also improvement of e-learning by mobile phones.
Modelo de un sistema multiagente para proveer ayudas adaptativas en ambientes virtuales de aprendizaje

Este articulo presenta la descripcion de un modelo multiagente para ofrecer ayudas adaptativas en ambientes virtuales de aprendizaje. Las ayudas para este tipo de ambientes, en su mayoria, estan pensadas de modo general, es decir, son iguales para todos los usuarios y no se consideran sus particularidades. Por tal razon, ofrecer ayudas personalizadas puede ser una estrategia para mejorar la flexibilidad de las aplicaciones de estas plataformas, donde se tenga en cuenta los tipos usuarios y sus modelos mentales individuales. El modelo propuesto esta basado en la metodologia Ingenias y permite la asignacion de ayudas y monitoreo de los usuarios a partir de su perfil y su interaccion con el aplicacion. Palabras clave : agentes software, ayudas adaptativas, ambientes virtuales de aprendizaje, metodologia ingenias, modelo multiagente.
Konzept zur Absicherung von CFD-Simulationen im Brandschutz und in der Gefahrenabwehr

Computergestutzte Simulationsrechnungen konnen ein wirksames Hilfsmittel sein, um schon in der Planung durch die geschickte Kombinationen von problemangepassten Masnahmen Brandauswirkungen zu begrenzen. Diese schutzzielorientierte Vorgehensweise ermoglicht prinzipiell die Entwicklung von individuellen Problemlosungen in der Planungsphase. Sowohl unser Wissen uber die bei den Branden ablaufenden Prozesse, als auch die zu ihrer Darstellung verfugbaren Rechenleistungen sind jedoch begrenzt. Die Simulations-methoden kommen daher nicht ohne vereinfachende Annahmen aus. Vertrauenswurdige Simulationsergebnisse erfordern deshalb von den Verantwortlichen ein akribisches Vorgehen und sehr spezielle Fachkenntnisse. Insbesondere dann, wenn auf Basis von Simulationsergebnissen fur den betrachteten Einzelfall Erfahrungswerte, wie z.B. maximale Fluchtweglangen oder Gebaudeeindringtiefen von Feuerwehreinsatzkraften, vernachlassigt werden. Wie aber kann eine grundliche Uberprufung und Absicherung durchgefuhrt werden? Das vorliegende Fachbuch beschreibt hierfur erstmalig nicht nur ein umfassendes Konzept, sondern zeigt die Notwendigkeit der Konzeptbestandteile auch anhand von einfachen Beispielen. Namhafte Experten aus dem Brandingenieurwesen und der numerischen Stromungsmechanik loben die fachubergreifenden Ausfuhrungen und Darstellungen als sehr gelungen und hilfreich.
A signal sequence is not required for protein export in prlA mutants of Escherichia coli.

The prlA/secY gene, which codes for an integral membrane protein component of the Escherichia coli protein export machinery, is the locus of the strongest suppressors of signal sequence mutations. We demonstrate that two exported proteins of E.coli, maltose‐binding protein and alkaline phosphatase, each lacking its entire signal sequence, are exported to the periplasm in several prlA mutants. The export efficiency can be substantial; in a strain carrying the prlA4 allele, 30% of signal‐sequenceless alkaline phosphatase is exported to the periplasm. Other components of the E.coli export machinery, including SecA, are required for this export. SecB is required for the export of signal‐sequenceless alkaline phosphatase even though the normal export of alkaline phosphatase does not require this chaperonin. Our findings indicate that signal sequences confer speed and efficiency upon the export process, but that they are not always essential for export. Entry into the export pathway may involve components that so overlap in function that the absence of a signal sequence can be compensated for, or there may exist one or more means of entry that do not require signal sequences at all.
What were they thinking? The Federal Reserve in the run-up to the 2008 financial crisis

ABSTRACT The Federal Reserve (the Fed) is responsible for monitoring, analyzing and ultimately stabilizing US financial markets. It also has unrivalled access to economic data, high-level connections to financial institutions, and a large staff of professionally trained economists. Why then was it apparently unconcerned by the financial developments that are now widely recognized to have caused the 2008 financial crisis? Using a wide range of Fed documents from the pre-crisis period, particularly the transcripts of meetings of the Federal Open Market Committee (FOMC), this paper shows that Fed policymakers and staff were aware of relevant developments in financial markets, but paid infrequent attention to them and disregarded significant systemic threats. Drawing on literatures in economics, political science and sociology, the paper then demonstrates that the Fed's intellectual paradigm in the years before the crisis focused on ‘post hoc interventionism’ – the institution's ability to limit the fallout should a systemic disturbance arise. Further, the paper argues that institutional routines played a crucial role in maintaining this paradigm and in contributing to the Fed's inadequate attention to the warning signals in the pre-crisis period.
The case for chaos in childhood epidemics. II. Predicting historical epidemics from mathematical models

The case for chaos in childhood epidemics rests on two observations. The first is that historical epidemics show various ‘fieldmarks’ of chaos, such as positive Lyapunov exponents. Second, phase portraits reconstructed from real-world epidemiological time series bear a striking resemblance to chaotic solutions obtained from certain epidemiological models. Both lines of evidence are subject to dispute: the algorithms used to look for the fieldmarks can be fooled by short, noisy time series, and the same fieldmarks can be generated by stochastic models in which there is demonstrably no chaos at all. In the present paper, we compare the predictive abilities of stochastic models with those of mechanistic scenarios that admit to chaotic solutions. The main results are as follows: (i) the mechanistic models outperform their stochastic counterparts; (ii) forecasting efficacy of the deterministic models is maximized by positing parameter values that induce chaotic behaviour; (iii) simple mechanistic models are equal if not superior to more detailed schemes that include age structure; and (iv) prediction accuracy for monthly notifications declines rapidly with time, so that, from a practical standpoint, the results are of little value. By way of contrast, next amplitude maps can successfully forecast successive changes in maximum incidence one or more years into the future.
A Message-Based Annotation System for Collaborative Design Review

The paper illustrates a shared annotation mechanism developed within a collaborative virtual environment for design review. This represents one of the first prototypes being developed within the European Project IMPROVE and it has been designed to be used within two distinct industrial scenarios: automotive and architectural design. The key feature of the system is that its functionalities (modelling, rendering, tracking) are distributed across a network of computers performing specific tasks and that the communication among these takes place through a standardised data message exchange. This paper shows the effectiveness of this approach by focusing on the implementation of the distributed annotation feature. Categories and Subject Descriptors ( according to ACM CCS ): I.3. 2 [Computer Graphics]: Distributed/network graphics
Is acupuncture effective in the treatment of fibromyalgia?

BACKGROUND We conducted this study to assess the effectiveness of acupuncture in the treatment of fibromyalgia syndrome (FMS), report any adverse effects, and generate hypotheses for future investigation. METHODS We searched MEDLINE, EMBASE, Manual Therapy Information System, the Cochrane registry, the University of Maryland Complementary and Alternative Medicine in Pain, the Centralized Information Service for Complementary Medicine, and the National Institutes of Health Office of Alternative Medicine databases for the key words "acupuncture" and "fibromyalgia. " Conference abstracts, citation lists, and letters supplemented the search. We selected all randomized or quasi-randomized controlled trials, or cohort studies of patients with FMS who were treated with acupuncture. Methodologic quality, sample characteristics, type of acupuncture treatment, and outcomes were extracted. Statistical pooling was not performed because of the differences in control groups. RESULTS Seven studies (3 randomized controlled trials and 4 cohort studies) were included; only one was of high methodologic quality. The high-quality study suggests that real acupuncture is more effective than sham acupuncture for relieving pain, increasing pain thresholds, improving global ratings, and reducing morning stiffness of FMS, but the duration of benefit following the acupuncture treatment series is not known. Some patients report no benefit, and a few report an exacerbation of FMS-related pain. Lower-quality studies were consistent with these findings. Booster doses of acupuncture to maintain benefit once regular treatments have stopped have been described anecdotally but not investigated in controlled trials. CONCLUSIONS The limited amount of high-quality evidence suggests that real acupuncture is more effective than sham acupuncture for improving symptoms of patients with FMS. However, because this conclusion is based on a single high-quality study, further high-quality randomized trials are needed to provide more robust data on effectiveness.
ASIC implementation of multimode frequency domain equalizer for heterogeneous wireless system

Heterogeneous wireless systems such as a combination of mobile broadband wireless access (MBWA) and wireless local area network (WLAN) are candidates to attain higher throughput and wide coverage in the next generation mobile communication systems. A multimode receiver to demodulate signals with multiple air interfaces is required in the heterogeneous systems. In this paper, we discuss an implementation of frequency domain equalizer (FDE) in the multimode receiver on an application specific integrated circuit (ASIC). The proposed multimode FDE could realize adaptively demodulate two systems (single carrier and multi carrier) depending on propagation environment. A multimode FDE ASIC is designed and implemented on 180-nm complementary metal-oxide semiconductor (CMOS). Core size of multimode FDE chip is 17.6 mm2. The experimental results show that the ASIC yields a throughput of 48.1 Mbit/s at a sampling rate of 100 MHz. The results also show that the power penalty of the measured bit error rate (BER) performance is only 1 dB at a BER of 10-3 in a 4-paths Rayleigh fading channel. We consider that the implemented ASIC is useful to demodulate signals with different air interfaces while optimally selecting an appropriate air interface in the heterogeneous wireless system.
Les structures énumératives à deux temps

Resume This paper deals with two-step enumerative structures. These textual objects are composed of a classic enumerative structure and a thematic enumeration elaborating on two or more noun phrases of the previous enumerative structure. – The components of a classic enumerative structure, an introductory sentence, co-items, and a closure are well-documented in the literature, whereas this is not true of two-step enumerative structures. We deal here with those composed of a classic enumeration (first step), a thematic enumeration, whose co-items are markers of thematization, and a closure (second step). – Analysis shows that the enumerable in the first step is either textually realized or is not, which modifies the role and nature of the co-items in the enumerative structure : when the enumerable is textually realized, the latter are exemplar co-items ; when the enumerable is not textually realized, they are landmark co-items.
AwareMe: Addressing Fear of Public Speech through Awareness

Fear of public speaking is an anxiety that most people encounter at some point in their lives. Some people with extreme fear of public speaking will avoid it at all costs, even if it means their personal, professional, and social growth may be hindered. AwareMe incorporates aspects of Cognitive Behavioral Therapy (CBT) and good public speaking practices to make an empowering assistive technology for people who suffer from different levels of public speaking anxiety. AwareMe is a device that provides feedback on voice pitch, filler words, and words per minute during presentation practice. It has a detachable wristband, worn during presentations, that provides visual and haptic feedback. Our approach differs from existing solutions because it focuses on bringing the users' attention to how their anxiety influences their speech patterns; this awareness helps them to directly improve their public speaking skills.
A Note on Processing Time of Biometric Identification

This paper evaluates an existing algorithm for biometric identification. In identification based on biometric images, the number of image comparisons is an important factor to estimate the total processing time in addition to the processing time of a single image comparison. Maeda et al. proposed an identification algorithm which reduces the number of image comparisons. This paper evaluates the algorithm in terms of the processing time and the accuracy with the features extracted by SIFT from palmprint images. The evaluation in this paper proves that the algorithm is applicable to the SIFT- based palmprint features.
A comparative study between Fractional-N PLL and Flying-Adder PLL

Frequency synthesis is one of the most important and most actively researched subjects in the field of VLSI mixed-signal circuit design. Among the existing techniques in this area, Fractional-N architecture is a widely used one for generating frequencies which are not integer multiple of the input reference frequency. Flying-Adder architecture is an emerging technique which is based on a new concept, Time-Average-Frequency, to generate frequencies. This paper presents an in-depth analysis and comparison between the two methods.
Applying Experimental Design and Regression Splines to High-Dimensional Continuous-State Stochastic Dynamic Programming

In stochastic dynamic programming (SDP) with continuous state and decision variables, the future value function is computed at discrete points in the state spac e. Interpolation can be used to approximate the values of the future value function between these discrete points. However, for large dimensional problems the number of discrete points required to obtain a good approximation of the future value function can be prohibitively large. Statistical methods of experimental design and function estimation may be employed to overcome this "curse of dimensionality. " In this paper, we describe a method for estimating the future value function by multivariate adaptive regression splines (MARS) fit over a discretization scheme based on orthogonal array (OA) experimental designs. Because orthogonal arrays only grow polynomially in the state-space dimension, our OA/MARS method is accurately able to solve higher dimensional SDP problems than previously possible. To our knowledge, the most efficient method published prior to this work employs tensor-product cubic splines to approximate the future value function (Johnson et al. 1993). The computational advantages of OA/MA RS are demonstrated in comparisons with the method using tensor-product cubic splines for applications of an inventory forecasting SDP with up to nine state variables computed on a small workstation. In particular, the storage of an adequate tensor-product cubic spline for six dimensions exceeds the memory of our workstation, and the run time for an accurate OA/MARS SDP solution would be at least an order of magnitude faster than using tensor-product cubic splines for higher than six dimensions.
Effectiveness and safety of ombitasvir, paritaprevir, ritonavir ± dasabuvir ± ribavirin: An early access programme for Spanish patients with genotype 1/4 chronic hepatitis C virus infection

Over the last 5 years, therapies for hepatitis C virus (HCV) infection have improved significantly, achieving sustained virologic response (SVR) rates of up to 100% in clinical trials in patients with HCV genotype 1. We investigated the effectiveness and safety of ombitasvir/paritaprevir/ritonavir±dasabuvir in an early access programme. This was a retrospective, multicentre, national study that included 291 treatment‐naïve and treatment‐experienced patients with genotype 1 or 4 HCV infection. Most patients (65.3%) were male, and the mean age was 57.5 years. The mean baseline viral load was 6.1 log, 69.8% had HCV 1b genotype, 72.9% had cirrhosis and 34.7% were treatment‐naïve. SVR at 12 weeks posttreatment was 96.2%. Four patients had virological failure (1.4%), one leading to discontinuation. There were no statistical differences in virological response according to genotype or liver fibrosis. Thirty patients experienced serious adverse events (SAEs) (10.3%), leading to discontinuation in six cases. Hepatic decompensation was observed in five patients. Four patients died during treatment or follow‐up, three of them directly related to liver failure. Multivariate analyses showed a decreased probability of achieving SVR associated with baseline albumin, bilirubin and Child‐Pugh score B, and a greater probability of developing SAEs related to age and albumin. This combined therapy was highly effective in clinical practice with an acceptable safety profile and low rates of treatment discontinuation.