Miracle-dz/UniFAR-FTUs huggingface dataset:
Industrial field service network planning: Existing methods in supply chain planning and modeling and their applicability for field services

Supply chain planning and modeling has been a major topic in operations management in the last years. This contribution provides a review of approaches for the design and management of supply chains in manufacturing. Although industrial field services have become a major business pillar for most western machine and equipment manufacturers, there is no guided approach for planning the infrastructure of the networks for industrial field service delivery yet. Based on case study research this paper identifies the unique characteristics and challenges of the service business of OEMs and external service providers for industrial goods. Furthermore, a conceptual framework for developing a structured and holistic approach for planning these networks is introduced.
Service Restoration Methodology for Multiple Fault Case in Distribution Systems

Current KEPCO's distribution automation system (DAS) provides a very effective restoration solution for the single fault case but cannot handle multiple faults. This paper proposes a two-step restoration scheme-sequential and simultaneous restoration-for multiple fault cases. Efficiency has been achieved by introduction of restoration performance index (RPI) and load-balancing algorithm. Test results to show effectiveness of the proposed scheme are presented, and field experience of DAS in Korea is described as well
Parallel interference cancellation with commutation signaling

This paper considers the SIC-subtractive interference cancellation and PIC-parallel interference cancellation with and without the ISI cancellation system-commutation signaling (CS), in a deep Rayleigh fading environment, time and frequency selective, assuming the spreading sequences and the features of the channels of the several interfering users is known. It is shown that SIC and PIC lead to better performance when the CS technique is used together, once these systems subtract the MAI estimated for each user. These estimates improve when the ISI is cancelled, since the MAI estimated depends upon the estimate of the transmitted symbols by each interfering user. A blind detection (without knowledge of spreading sequences nor the features of the channels of the interfering users) with a noise whitening matched filter (NWMF) that combats the MAI through the whitening of the interfering power spectrum (following the single-user philosophy) is also developed.
Plo1 phosphorylates Dam1 to promote chromosome bi-orientation in fission yeast

The fungal-specific heterodecameric outer kinetochore DASH complex facilitates the interaction of kinetochores with spindle microtubules. In budding yeast, where kinetochores bind a single microtubule, the DASH complex is essential, and phosphorylation of Dam1 by the Aurora kinase homologue, Ipl1, causes detachment of kinetochores from spindle microtubules. We demonstrate that in the distantly related fission yeast, where the DASH complex is not essential for viability and kinetochores bind multiple microtubules, Dam1 is instead phosphorylated on serine 143 by the Polo kinase homologue, Plo1, during prometaphase and metaphase. This phosphorylation site is conserved in most fungal Dam1 proteins, including budding yeast Dam1. We show that Dam1 phosphorylation by Plo1 is dispensable for DASH assembly and chromosome retrieval but instead aids tension-dependent chromosome bi-orientation.
A BLUE POINT SOURCE AT THE LOCATION OF SUPERNOVA 2011DH

We present Hubble Space Telescope (HST) observations of the field of the Type IIb supernova (SN) 2011dh in M51 performed at ≈1161 rest-frame days after explosion using the Wide Field Camera 3 and near-UV filters F225W and F336W. A star-like object is detected in both bands and the photometry indicates it has negative (F225W − F336W) color. The observed object is compatible with the companion of the now-vanished yellow supergiant progenitor predicted in interacting binary models. We consider it unlikely that the SN is undergoing strong interaction and thus estimate that it makes a small contribution to the observed flux. The possibilities of having detected an unresolved light echo or an unrelated object are briefly discussed and judged unlikely. Adopting a possible range of extinction by dust, we constrain parameters of the proposed binary system. In particular, the efficiency of mass accretion onto the binary companion must be below 50%, if no significant extinction is produced by newly formed dust. Further multiband observations are required in order to confirm the identification of the object as the companion star. If confirmed, the companion star would already be dominant in the UV–optical regime, so it would readily provide a unique opportunity to perform a detailed study of its properties.
Mobile computing and the quality of home care nursing practice

We investigated the effects of the introduction of mobile computing on the quality of home care nursing practice in Québec. The software, which structured and organized the nursing activities in patients' homes, was installed sequentially in nine community health centres. The completeness of the nursing notes was compared in 77 paper records (pre-implementation) and 73 electronic records (post-implementation). Overall, the introduction of the software was associated with an improvement in the completeness of the nursing notes. All 137 nurse users were asked to complete a structured questionnaire. A total of 101 completed questionnaires were returned (74% response rate). Overall, the nurses reported a very high level of satisfaction with the quality of clinical information collected. A total of 57 semi-structured interviews were conducted and most nurses believed that the new software represented a user-friendly tool with a clear and understandable structure. A postal questionnaire was sent to approximately 1240 patients. A total of 223 patients returned the questionnaire (approximately 18% response rate). Overall, patients felt that the use of mobile computing during home visits allowed nurses to manage their health condition better and, hence, provide superior care services. The use of mobile computing had positive and significant effects on the quality of care provided by home nurses.
CCR4-Associated Factor CAF1 Is an Essential Factor for Spermatogenesis

ABSTRACT The CCR4-associated protein CAF1 has been demonstrated to play several roles in the control of transcription and of mRNA decay. To gain further insight into its physiological function, we generated CAF1-deficient mice. They are viable, healthy, and normal in appearance; however, mCAF1 −/− male mice are sterile. The crossing of mCAF1 +/− mice gave a Mendelian ratio of mCAF1 +/+, mCAF1 +/−, and mCAF1 −/− pups, indicating that haploid mCAF1-deficient germ cells differentiate normally. The onset of the defect occurs during the first wave of spermatogenesis at 19 to 20 days after birth, during progression of pachytene spermatocytes to haploid spermatids and spermatozoa. Early disruption of spermatogenesis was evidenced by Sertoli cell vacuolization and tubular disorganization. The most mature germ cells were the most severely depleted, but progressively all germ cells were affected, giving Sertoli cell-only tubes, large interstitial spaces, and small testes. This phenotype could be linked to a defect(s) in germ cells and/or to inadequate Sertoli cell function, leading to seminiferous tubule disorganization and finally to a total disappearance of germ cells. The mCAF1-deficient mouse provides a new model of failed spermatogenesis in the adult that may be relevant to some cases of human male sterility.
Dcp2 Decapping Protein Modulates mRNA Stability of the Critical Interferon Regulatory Factor (IRF) IRF-7

ABSTRACT The mammalian Dcp2 mRNA-decapping protein functions primarily on a subset of mRNAs in a transcript-specific manner. Here we show that Dcp2 is an important modulator of genes involved in the type I interferon (IFN) response, which is the initial line of antiviral innate immune response elicited by a viral challenge. Mouse embryonic fibroblast cells with reduced Dcp2 levels (Dcp2β/β) contained significantly elevated levels of mRNAs encoding proteins involved in the type I IFN response. In particular, analysis of a key type I IFN transcription factor, IFN regulatory factor 7 (IRF-7), revealed an increase in both IRF-7 mRNA and protein in Dcp2β/β cells. Importantly, the increase in IRF-7 mRNA within the background of reduced Dcp2 levels was attributed to a stabilization of the IRF-7 mRNA, suggesting that Dcp2 normally modulates IRF-7 mRNA stability. Moreover, Dcp2 expression was also induced upon viral infection, consistent with a role in attenuating the antiviral response by promoting IRF-7 mRNA degradation. The induction of Dcp2 levels following a viral challenge and the specificity of Dcp2 in targeting the decay of IRF-7 mRNA suggest that Dcp2 may negatively contribute to the innate immune response in a negative feedback mechanism to restore normal homeostasis following viral infection.
On the evaluation of soft-errors detection techniques for GPGPUs

Recently, General Purpose Graphic Processing Units (GPGPUs) have begun to be preferred to CPUs for several computationally intensive applications, not necessarily related to computer graphics. However, due to their complexity GPGPUs also show a relatively high sensitivity to soft errors. Hence, there is some interest in devising and applying software techniques able to exploit their computational power by just acting on the executed code. In this paper we report some preliminary results obtained by applying two different software redundancy techniques aimed at soft-error detection; these techniques are completely algorithm independent, and have been applied on a sample application running on a Commercial-Off-The-Shelf GPGPU. The results have been gathered resorting to a neutron testing campaign. Some experimental results, explaining the capabilities of the methods, are presented and commented.
Multi-scale structure-preserving image filtering

Edge-preserving filtering is vital in many image processing and computer vision tasks. However, existing techniques, such as the bilateral filter and the guided filter, have limitations when dealing with stronger filtering strengths, resulting in the suppression of image structures. In this work, we discuss an alternative structure-preserving image filter (SPIF) that operates on multiple detail densities (i.e. scales) so as to overcome the trade-off between filtering strength and edge-preservation. We show, using several experiments, that the proposed filter is capable of performing various tasks, specifically detail enhancement and image abstraction, while maintaining low computational times. The parameterization of the proposed filter provides a high degree of flexibility, allowing it to perform well for the aforementioned tasks, and potentially, in many other tasks.
A Service Model for 6LoWPAN Wireless Sensor Networks

This paper proposes a 6LoWPAN service model based on the IPv6-based k-Anycast communication model. This model is extended into 6LoWPAN service model so that the data-centric services of WSN can be achieved efficiently in the address-centric 6LoWPAN. In the proposed service model, an IPv6 node can obtain multiple network services through one request-response interaction where multiple sensor nodes cooperate to complete all requested network services and they provide their respective network services at the same time. As a result, the delay time is shortened. In addition, the proposed service model avoids the service failure caused by dormant sensor nodes. Since users can only request the network services they are interested in, the redundant data transmission is avoided. The performance parameters of the proposed service model are analyzed, and the data results show that the performance of the proposed service model is better.
A trust prediction approach by using collaborative filtering and computing similarity in social networks

Along with the increasing popularity of social web sites, users rely more on the trustworthiness information for many online activities among users. However, such social network data often suffers from severe data sparsity and aren't able to provide users with enough information. Therefore, trust prediction has emerged as an important topic in social network research. Nowadays, trust prediction is not calculated with high accuracy. Collaborative filtering approach has become more applicable and is almost used in recommendation systems. In this approach, it is tried tha-tusers' rating of certain areas to be gathered and the similarity of users or items are measured, the most suitable and nearest item of user's preference will be realized and recommended. By using this concept and the most innovative and available approach to measure similarity is recommended to the target user. Then the trusted user is found. The results demonstrate that the recommended approach significantly improves the accuracy of trust prediction in social networks.
Root and shoot development of Rumex species under waterlogged conditions

The responses of Rumex acetosa, Rumex crispus, and Rumex palustris to different levels of waterlogging were studied in sand culture experiments. Rumex crispus and R. palustris developed new flooding-resistant roots as a response to waterlogging. The growth of these new roots caused a changed vertical distribution of the root length in these species; most root length was concentrated in the upper 10 cm of the soil. Rumex acetosa did not show significant development of flooding-resistant roots and did not change its vertical root distribution during flooding of the soil. The results of the experiments indicate that growth expressed as relative growth rate is positively correlated to the development of new flooding-resistant roots under waterlogged conditions. We concluded that R. crispus and R. palustris are more resistant to waterlogging than R. acetosa; this agrees with the distribution of these Rumex species in the field. However, waterlogging resistance is probably only one of the factors influencing di.
Sedentary Behavior and Arterial Stiffness in Adults with and without Metabolic Syndrome

Abstract This study aimed to investigate whether sedentary time (Sed) and physical activity (PA) are associated with arterial stiffness in individuals with and without metabolic syndrome (MetS). This cross-sectional study comprised 197 individuals (47±13 years; 58% female) from a primary health care centre. Arterial stiffness was assessed using carotid-femoral pulse wave velocity (cfPWV). Metabolic syndrome was determined as clustering of at least 3 out of 5 risk factors (central obesity, hypertension, impaired glucose, triglycerides and high-density lipoprotein cholesterol). Daily PA was objectively assessed and classified in Sed, light and moderate-to-vigorous PA. Physical activity was used as a continuous variable for multiple regression analysis. For mean comparisons of cfPWV between subjects with and without MetS, a binary split at the median of Sed and PA was used. Sedentary time was associated with cfPWV (β=0.11; p=0.01) explaining 1.3% of its variance; independently of age (β=0.49; p<0.001), systolic blood pressure (β=0.27; p<0.001) and fasting glucose (β=0.19; p<0.001). Participants with MetS and more Sed had higher cfPWV than those with MetS and less Sed (9.9±1.0 vs. 8.9±1.0 m/s; p<0.05). Sedentary time is associated with cfPWV independently of age and metabolic risk factors. A higher Sed in MetS individuals lead to a worse arterial stiffness profile.
Fault-tolerant quantum computation with cluster states

The one-way quantum computing model introduced by Raussendorf and Briegel [Phys. Rev. Lett. 86, 5188 (2001)] shows that it is possible to quantum compute using only a fixed entangled resource known as a cluster state, and adaptive single-qubit measurements. This model is the basis for several practical proposals for quantum computation, including a promising proposal for optical quantum computation based on cluster states [M. A. Nielsen, Phys. Rev. Lett. (to be published), quant-ph/0402005]. A significant open question is whether such proposals are scalable in the presence of physically realistic noise. In this paper we prove two threshold theorems which show that scalable fault-tolerant quantum computation may be achieved in implementations based on cluster states, provided the noise in the implementations is below some constant threshold value. Our first threshold theorem applies to a class of implementations in which entangling gates are applied deterministically, but with a small amount of noise. We expect this threshold to be applicable in a wide variety of physical systems. Our second threshold theorem is specifically adapted to proposals such as the optical cluster-state proposal, in which nondeterministic entangling gates are used. A critical technical component of our proofs is two powerful theorems which relate the properties of noisy unitary operations restricted to act on a subspace of state space to extensions of those operations acting on the entire state space. We expect these theorems to have a variety of applications in other areas of quantum-information science.
Stigma as a barrier to recovery: Adverse effects of perceived stigma on social adaptation of persons diagnosed with bipolar affective disorder.

OBJECTIVE The purpose of this study was to evaluate the effect of concerns about stigma on social adaptation among persons with a diagnosis of bipolar affective disorder. METHODS The sample comprised 264 persons who were consecutively admitted to a psychiatric inpatient or outpatient service at a university-affiliated hospital and who met research diagnostic criteria for bipolar I disorder, bipolar II disorder, or schizoaffective disorder, manic type. Patients were evaluated with use of the Schedule for Affective Disorders and Schizophrenia, Lifetime Version (SADS-L), the Brief Psychiatric Rating Scale (BPRS), and a measure of perceived stigma. Social adjustment was measured at baseline and seven months later with the Social Adjustment Scale (SAS). RESULTS As predicted, patients who had concerns about stigma showed significantly more impairment at seven months on the social leisure subscale but not on the SAS extended family subscale, after baseline SAS score and symptom level had been controlled for. More refined models using SAS-derived factors as dependent variables indicated that concerns about stigma predicted higher avoidance of social interactions with persons outside the family and psychological isolation at seven-month follow-up, after baseline SAS and BPRS scores had been controlled for. CONCLUSIONS Concerns about the stigma associated with mental illness reported by patients during an acute phase of bipolar illness predicted poorer social adjustment seven months later with individuals outside the patient's family. Greater attention to patients' concerns about stigma is needed from both researchers and clinicians.
Reliability of next generation high performance pMEMS™ resonator oscillators

Long term reliability of piezoelectric micro-electro mechanical systems (pMEMS™) resonators and oscillators has been characterized for high performance frequency reference applications. In particular, high-Q piezoelectric bulk acoustic wave (BAW) resonators exhibit aging (frequency drift) within measurement system accuracy (±2ppm) under two long-term measurement conditions: over 9 months at 25°C, and over 1400 hours at 125°C.
Development and Evaluation of Lyophilized Thiolated-Chitosan Wafers for Buccal Delivery of Protein

Annealed and non-annealed freeze-dried wafers from synthesised thiolated-chitosan have been developed and evaluated. Wafers were obtained by freeze-drying aqueous gels of the thiolated polymer incorporating per polymer weight, 10 % each of glycerol as plasticizer, D-mannitol as cryoprotectant and 50% BSA as model protein drug. The formulation was freeze-dried with or without the process of annealing. Texture analyzer was employed to investigate the in vitro mucoadhesive properties in tensile mode, residual moisture content by thermo-gravimetric analysis (TGA) while hydration capacity and drug release studies were performed in 0.1M PBS. Microscopic architecture was examined using scanning electron microscopy (SEM). Differential scanning calorimetry (DSC) was employed for protein phase separation studies and conformational stability by attenuated total reflectance-Fourier transform infra-red spectroscopy (ATR-FTIR) and confirmed with Circular dichroism (CD). The annealing process led to wafers with increased ease of hydration, improved in vitro mucoadhesive characteristics and enhanced BSA release, without affecting the conformational stability of the protein due to the presence of a cryoprotectant. These results show the potential application of annealed freeze-dried thiolatedchitosan wafers for buccal mucosa delivery of protein based drugs.
X–ray and neutron diffraction studies and MD simulation of atomic configurations in polyamorphic Y2O3-Al2O3 systems

Supercooled liquids in the Y2O3-Al2O3 system undergo a liquid–liquid phase transition between a high–temperature, high–density amorphous (HDA) polymorph form and one with lower density (LDA form) that is stable at lower temperature. The two amorphous polymorphs have the same chemical composition, but they differ in their density (ca. 4% difference) and in their heat content (enthalpy) and entropy determined by calorimetry. Here we present new results of structural studies using neutron and high–energy X–ray diffraction to study the structural differences between HDA and LDA polyamorphs. The combined datasets show no large differences in the average nearest–neighbour Al−O or Y−O bond lengths or coordination numbers between the low– and high–density liquids. However, the data indicate that substantial changes occur among the packing geometries and clustering of the Al−O and Y−O coordination polyhedra, i.e. within the second–nearest–neighbour shell defined by the metal–metal (i.e. Y−Y, Y−Al, Al−Al) interactions. Polarizable ion model molecular dynamics simulations of Y2O3−Al2O3 liquids are used to help interpret the pair–correlation functions obtained from X–ray and neutron scattering data. Unexpectedly large density fluctuations are observed to occur during the simulation of nominally equilibrated systems. These are interpreted as being due to dynamic sampling of high– and low–density configurations within the single–phase liquid at temperatures above the critical point or phase transition line. Calculated partial radial distribution functions indicate that the primary differences between HDA and LDA configurations occur among the Y−Y correlations.