Miracle-dz/UniFAR-FTUs huggingface dataset:
Thinking of Perfecting the Financial Transfer Payment System of the Ethnic Autonomous Regions

The financial transfer payment system of the ethnic autonomous regions has its own features and has had much progress.However,there are still many issues of policies and laws with their concrete situations: fuzzy right boundaries of the business powers and financial powers between the central and local governments;the current financial transfer payment system lacks authority of law;there are many points not adapted to the Law on Regional National Autonomy with weak adjustment and control as well as weak equalization capabilities.Therefore,we should improve many aspects of autonomous local financial transfer payment system,such as strengthening the legal system of transfer payments,scientifically and legally clear the division between the central government and local governments,the financial authority areas,and continue with principle of unity of powers and financial authority;moderately increase the size of the transfer payment of funds and increase formulaic transfer payments;establish a profit incentive mechanism to promote government at the same level of horizontal transfer payments.Finally,form supervision framework with multi-combination supervised by government.
Coplanar waveguide monopole antenna on artificial magnetic conductor for body-worn wireless communication systems

We report in this paper the design and the realization of a monopole antenna directly placed over an artificial magnetic conductor (AMC) without the need of additional space between them. Simulation results and measurements are in good agreement and show that the antenna performances are as good as the best ones reported so far in literature while having a smaller volume. The antenna works at 1.916 GHz with a bandwidth of 8%. The adaptation of the antenna is -35 dB. Measurement of the antenna gain is 4.7 dBi with a front-to-back radiation ratio of 15.8 dB. Simulation results also show that the AMC isolates well the monopole from of the body: the localized SAR value calculated with 1 g of tissue is 0.34 W/kg with an injected power of 1W. The antenna with the AMC is well adapted for wearable applications.
Balance sheet valuation of shares based on fair value in active markets estimated on the basis of economic and financial models

Financial instruments pose a number of problems in economic sciences, especially in accountancy which deals with continuous measurements of these instruments in practice. One of the major problems is the use of fair value is valuating financial instruments. According to this category, two basic financial instruments ca be identified – instruments whose prices are determined by active markets and those for which such prices and markets do not exist. The first class is valuated on the basis of accounting categories while the second type of instruments is valuated on the basis of value estimation models and techniques. The paper presents the models for balance sheet valuation of shares based on fair value in active markets estimated on the basis of economic and financial models. The paper aims to present the results of empirical research and a comparison, on the basis of statistical methods, of valuations based on the actual fair value and estimated share values determined by economic and financial methods
Treatment of nonresectable hepatocellular carcinoma with intrahepatic 90Y-microspheres.

UNLABELLED Treatment for nonresectable hepatocellular carcinoma (HCC) is palliative. The relatively greater arteriolar density of hepatic tumors compared with normal liver suggests that intrahepatic arterial administration of 90Y-microspheres can be selectively deposited in tumor nodules and results in significantly greater radiation exposure to the tumor than external irradiation. The purpose of this study was to determine the proportion (frequency) and duration of response, survival, and toxicity after intrahepatic arterial injection of 90Y-microspheres in patients with HCC. METHODS Patients with documented HCC, Eastern Cooperative Oncology Group performance status 0-3, adequate bone marrow, and hepatic and pulmonary function were eligible for study. Patients who had significant shunting of blood to the lungs or gastrointestinal (GI) tract or who could not undergo cannulation of the hepatic artery were excluded. Patients received a planned dose of 100 Gy through a catheter placed into the hepatic artery. RESULTS Twenty-two patients were treated with 90Y-microspheres; 20 of the treated patients (median age, 62.5 y) were evaluated for treatment efficacy. Nine patients were Okuda stage I, and 11 were Okuda stage II. The median dose delivered was 104 Gy (range, 46-145 Gy). All 22 treated patients experienced at least 1 adverse event. Of the 31 (15%) serious adverse events, the most common were elevations in liver enzymes and bilirubin and upper GI ulceration. The response rate was 20%. The median duration of response was 127 wk; the median survival was 54 wk. Multivariable analysis suggested that a dose >104 Gy (P = 0.06), tumor-to-liver activity uptake ratio >2 (P = 0.06), and Okuda stage I (P = 0.07) were associated with longer survival. CONCLUSION Significantly higher doses of radiation can be delivered to a HCC tumor by intrahepatic arterial administration of 90Y-microspheres than by external beam radiation. This treatment appears to be beneficial in nonresectable HCC with acceptable toxicity.
Biochemical Characterization of Hpa2 and Hpa3, Two Small Closely Related Acetyltransferases from Saccharomyces cerevisiae*

Background: Based on their sequences, the closely related yeast Hpa2 and Hpa3 proteins appear to be acetyltransferases. Results: Hpa2 and Hpa3 acetylate histones, polyamines, and some small basic proteins. Conclusion: Although Hpa2 and Hpa3 are very similar in sequence, they have somewhat different substrate preferences. Significance: This is the first biochemical characterization of these two acetyltransferases. Based on their sequences, the Saccharomyces cerevisiae Hpa2 and Hpa3 proteins are annotated as two closely related members of the Gcn5 acetyltransferase family. Here, we describe the biochemical characterization of Hpa2 and Hpa3 as bona fide acetyltransferases with different substrate specificities. Mutational and MALDI-TOF analyses showed that Hpa3 translation initiates primarily from Met-19 rather than the annotated start site, Met-1, with a minor product starting at Met-27. When expressed in Escherichia coli and assayed in vitro, Hpa2 and Hpa3 (from Met-19) acetylated histones and polyamines. Whereas Hpa2 acetylated histones H3 and H4 (at H3 Lys-14, H4 Lys-5, and H4 Lys-12), Hpa3 acetylated only histone H4 (at Lys-8). Additionally, Hpa2, but not Hpa3, acetylated certain small basic proteins. Hpa3, but not Hpa2, has been reported to acetylate d-amino acids, and we present results consistent with that. Overexpression of Hpa2 or Hpa3 is toxic to yeast cells. However, their deletions do not show any standard phenotypic defects. These results suggest that Hpa2 and Hpa3 are similar but distinct acetyltransferases that might have overlapping roles with other known acetyltransferases in vivo in acetylating histones and other small proteins.
A Maximum Power Point tracker for a photovoltaic system under changing luminosity conditions

In order to increase the output efficiency of a PV energy system, it has to be forced to operate near the maximum power point (MPP). A photovoltaic (PV) system, including Maximum Power Point Tracking (MPPT) controller that extracts the maximum possible output power from the solar panel is built. Simulation and experimental results show that the proposed system, making use of several MPPT control algorithms (Perturb and Observe (P&O), Incremental conductance (INC), Fuzzy Logic), provides good tracking performance.
Investigating virtual reality navigation in amnestic mild cognitive impairment using fMRI

ABSTRACT Spatial navigation requires a well-established network of brain regions, including the hippocampus, caudate nucleus, and retrosplenial cortex. Amnestic Mild Cognitive Impairment (aMCI) is a condition with predominantly memory impairment, conferring a high predictive risk factor for dementia. aMCI is associated with hippocampal atrophy and subtle deficits in spatial navigation. We present the first use of a functional Magnetic Resonance Imaging (fMRI) navigation task in aMCI, using a virtual reality analog of the Radial Arm Maze. Compared with controls, aMCI patients showed reduced activity in the hippocampus bilaterally, retrosplenial cortex, and left dorsolateral prefrontal cortex. Reduced activation in key areas for successful navigation, as well as additional regions, was found alongside relatively normal task performance. Results also revealed increased activity in the right dorsolateral prefrontal cortex in aMCI patients, which may reflect compensation for reduced activations elsewhere. These data support suggestions that fMRI spatial navigation tasks may be useful for staging of progression in MCI.
Secretome analysis of ionizing radiation‐induced senescent cancer cells reveals that secreted RKIP plays a critical role in neighboring cell migration

Cellular senescence is a physiological program of irreversible growth arrest that is considered to play an important role in tumor suppression. Recent studies demonstrated that senescent cells secrete multiple growth regulatory proteins that could alter the behavior of neighboring cells. In this study, we investigated the effect of secretory proteins from ionizing radiation (IR) induced senescent tumor cells on normal and tumor cells. Conditioned medium (CM) from IR‐induced senescent MCF7 cells significantly increased cell proliferation, invasion, migration, and wound healing activity in MCF7 cells and HUVECs. Comparative proteomics analysis revealed 24 differentially secreted protein spots including Raf kinase inhibitor protein (RKIP), α‐Enolase, AKAP9, and MARK4, and the findings were confirmed by Western blot analysis of IR‐induced senescent cancer cells. We found that RKIP was secreted via the classical pathway, and the transfection of small interfering RNA against RKIP suppressed CM‐induced migration in MCF7 cells. Treatment with recombinant human RKIP increased the migratory activity of MCF7 cells. Taken together, our results demonstrate that the senescence‐associated secretory protein RKIP could be the principal target to prevent the potential effects of the secretome from IR‐induced senescent tumor cells on neighboring cell migration.
Optimal Filtering for Incompletely Measured Polynomial States over Linear Observations

In this paper, the optimal filtering problem for incompletely measured polynomial system states over linear observations is treated proceeding from the general expression for the stochastic Ito differential of the optimal estimate and the error variance. In contrast to the previous works, the nonlinear polynomial states are allowed to be unmeasured in this problem. The procedure for obtaining a closed system of the filtering equations for any polynomial state over linear observations is then established, which yields the explicit closed form of the filtering equations in the particular case of a bilinear state equation. In the example, performance of the designed optimal filter is verified against a conventional extended Kalman-Bucy filter.
Pengaruh Kebijakan Dividen, Earning Volatility, dan Leverage terhadap Volatilitas Harga Saham pada Perusahaan Non-financing yang Terdaftar di Bursa Efek Indonesia Tahun 2010-2014

The research examines the effect of dividend policy, earnings volatility, and leverage on share price volatility of non financing companies listed in Indonesia Stock Exchange in 2010-2014. Dividend policy variabel using dividend payout ratio and leverage variabel using debt to equity ratio. Secondary data were sourced from the financial statements, published by the capital market reference center at the Indonesia Stock Exchange. The research type used in this research is hypothesis testing, by using simple random sampling method. There are 195 samples of the data that become the object to be researched. This research uses multiple linear regression analysis to test the hypothesis. The results of this research show that simultaneous of dividend payout ratio, earnings volatility, and leverage have effect on share price volatility. Partially the research shows that (1) dividend payout ratio have negative effect on share price volatilty, (2) earnings volatility have positive effect on share price volatility, and (3) leverage have positive effect on share price volatility. Keywords : Dividend Policy, Earnings Volatility, Leverage, and Share Price Volatility
Distinguishing Hepatic Metastases From Hemangiomas: Qualitative and Quantitative Diagnostic Performance Through Dual Echo Respiratory-Triggered Fast Spin Echo Magnetic Resonance Imaging

Objective: To determine the relative value of qualitative (reader opinion) and quantitative (values derived from dual echo T2 fast spin echo [FSE]) measures in distinguishing hepatic metastases from hemangiomas. Methods: Forty-nine patients with hemangiomas and 23 with metastases were studied with dual echo respiratory-triggered FSE and dynamic 2-dimensional spoiled gradient echo (GRE) imaging. Lesion T2 was estimated from signal intensity ratios on the first and second echoes. Two experienced radiologists independently evaluated groups of images based on 5 separate qualitative measures: first echo FSE, second echo FSE, first and second echo FSE, dynamic GRE, and all images together. Results: The mean calculated T2s were 226 ± 74 milliseconds for hemangiomas and 105 ± 22 milliseconds for metastases (P < 0.001). A T2 cutoff of 130 milliseconds distinguished metastases from hemangiomas with a sensitivity of 94%, specificity of 91%, and accuracy of nearly 94%. There was no significant difference between the best quantitative measure and the best qualitative measure for either reader. Conclusion: Liver lesion T2 relaxation times calculated from dual echo FSE images provide information useful in discriminating metastases from hemangiomas, as does reader opinion.
Segment routing in hybrid software-defined networking

Software-defined networking (SDN) decouples the network into different layers, bringing many new attributes over traditional network. But SDN also comes with its own set of challenges and limitations. Combining the mature traditional network with new benefits of SDN, hybrid SDN has attracted significant attention. On the other hand, segment routing keeps partial routing information within packet header so that switch can directly dispatch without calculate routing path or looking flow entry table. In this paper, we first propose a mechanism which integrates segment routing into hybrid SDN that can reduce the needs of flow entries of SDN switch. Then we formulate a routing algorithm for this mechanism. Our algorithm considers the balance of traffic load and reduces the needs of flow entries in each switch. Simulation results show that the performance of our mechanism significantly reduces the number of flow entries than compared solution, and achieves better load balance compared with previous routing protocols.
Emerging commercial molecular tests for the diagnosis of bloodstream infection

Bloodstream infection (BSI) by microorganisms can lead to sepsis. This condition has a high mortality rate, which rises significantly with delays in initiation of appropriate antimicrobial treatment. Current culture methods for diagnosing BSI have long turnaround times and poor clinical sensitivity. While clinicians wait for culture diagnosis, patients are treated empirically, which can result in inappropriate treatment, undesirable side effects and contribute to drug resistance development. Molecular diagnostics assays that target pathogen DNA can identify pathogens and resistance markers within hours. Early diagnosis improves antibiotic stewardship and is associated with favorable clinical outcomes. Nonetheless, limitations of current molecular diagnostic methods are substantial. This article reviews recent commercially available molecular methods that use pathogen DNA to diagnose BSI, either by testing positive blood cultures or directly testing patient blood. We critically assess these tests and their application in clinical microbiology. A view of future directions in BSI diagnosis is also provided.
Practitioner-Initiated Workplace-Based Conjoint Collaboration within an Adult Education Institution toward Democratic Schooling: A Distributed Leadership Perspective

This paper examines an account of a practitioner-initiated transformation of workplace-based social relationship within a grassroots adult education institution. This tripartite relationship among adult students, staff and teachers, abbreviated as AST, is a major driving force for activities and missionary functioning of the XinZhuang Community University (XZ-CU) and thus constitutes an indication of conjoint collaboration. Grafted from historical context and the development stage of AST, the initiative and the intervention focused on redefining AST relationship from a distributed leadership perspective and represents a democratic core and alternative to school leadership that would render new opportunity to create ‘democratic structures and processes' that a Democratic School advocated. This work has led to the conception and practice of joint educational experiment with elementary schools. The objectives of this research (as a professional engagement) are two-fold: first, to outline the major observables of this engagement, including reviews of facilitating the evolution of AST relationship in past three years. Second, with the Cultural Historical Activity Theory (CHAT) and its variant as the theoretical lens for framing and understanding the phenomena, we then identify the critical contradictions and concerted efforts of transformation, along with outcomes that emerged and artefacts employed, as well as further impacts of school reform on structures and processes.
Loss of cyclin‐dependent kinase inhibitors produces adipocyte hyperplasia and obesity

Adipocyte hyperplasia is characteristic of some forms of human obesity, but the role of adipocyte number in obesity and how normal adipocyte number is established are unclear. Preadipocytes proliferate and then differentiate to become mitotically quiescent adipocytes. This involves exit from the cell cycle, a process regulated by cell cycle inhibitors such as the cyclin‐ dependent kinase inhibitors (CDKIs) p27 and p21. 3T3‐L1 preadipocytes show marked changes in p27 and p21 during differentiation, suggesting CDKIs may regulate establishment of adipocyte number in vivo. To study the role of these CDKIs in adipogenesis, we analyzed adult p27 knockout (p27KO), p21 knockout (p21KO), p27/p21 double knockout (DBKO), and wild‐ type (WT) mice. Adult DBKO mice weighed 100% more and had fourfold increases in body fat percentage compared with WT. Fat pad weights were increased 80, 90, and 500% in p27KO, p21KO, and DBKO mice, respectively, compared with WT. Adipocyte numbers of p27KO, p21KO, and DBKO mice were 1.9‐, 1.7‐, and 6.1‐fold, respectively, that of WT; adipocyte size was not increased. DBKO mice showed glucose intolerance, insulin insensitivity, hepatic steatosis and dyslipidemia; gradations of these effects occurred in p27KO and p21KO mice. In conclusion, p27KO and p21KO mice are obese because of adipocyte hyperplasia, and DBKO mice have further increases in obesity and adipocyte hyperplasia, indicating that their functions in establishing adipocyte number are not redundant. p27 and p21 are major regulators of adipocyte number in vivo, and knockouts lacking one or both of these proteins provide models for producing adipocyte hyperplasia and understanding its metabolic consequences.
Hand activity detection from electromyogram using instantaneous frequency

In this paper, we analyze the electromyogram signal for detection of activity in human hand. The ensemble empirical mode decomposition (EEMD) algorithm is used to represent the electromyogram signal in terms of intrinsic mode functions (IMFs). Then instantaneous frequency is estimated on the EEMD generated IMFs. Unlike Fourier frequency, instantaneous frequency is a function of time making it useful to analyze signals that have time-varying spectral properties, such as the electromyogram signals. We propose a novel mean instantaneous frequency parameter and compare its performance with conventional parameters namely mean absolute value and mean frequency for detection of muscle activity in human hand. Results for actual electromyogram signals obtained from an open source database and those recorded by us using the miBEAT setup are presented.
Coalitional Games for Resource Allocation in the Device-to-Device Uplink Underlaying Cellular Networks

With emergency of demands for local area services, device-to-device (D2D) communication is proposed as a vital technology component for the next generation cellular communication system to improve spectral reuse and enhance system capacity. These benefits depend on efficient interference management and resource allocation. Existing works usually consider these problems under a restricted cellular system consisting of a pair of D2D users and a cellular user. In this paper, we address the uplink resource allocation problem for multiple D2D and cellular users from a game theory point of view. Combing different transmission modes, mutual interferences, and resource sharing policy in a single utility function, we propose a coalition formation game based scheme. By theoretical analysis, we prove that it converges to Nash-stable equilibrium and further approaches to the system optimal solution with geometric rate. By extensive simulations, we demonstrate the effectiveness of our proposed scheme, which achieves the close optimum solution obtained by the centralized exhaustive algorithm and enhances the system sum rate by about 20%-65% without sacrifice of resource sharing fairness compared with several other practical strategies.
[Risk indicators for dental caries in preschool children from La Boquilla, Cartagena].

OBJECTIVE Describing the occurrence of dental caries in preschool children from the Boquilla neighbourhood in Cartagena and relating it to risk factors reported in the medical literature. METHODS The sample consisted of 238 preschool children aged 3 to 5. Average age was 4.1. Regarding gender, there were 116 boys and 122 girls. The children were individually selected in a probabilistic way, bearing in mind the size of the population from the chosen educational institution; a questionnaire and clinical instrument were used. The data was analysed according to outcome using Odd ratios for bivariate analysis and logistical regression for multivariable analysis. RESULTS Caries prevalence was 60 %, mainly occurring amongst 5 year old children. The major risk factors observed were parents having not progressed to more than secondary level studies and a background of caries. A 26.6 OR was obtained at the moment of adjusting the logistical regression estimators for having a background of caries, 3.37 OR for daily candy consumption and 2.17 OR for non-exposure to fluorides. CONCLUSIONS The presence of caries in this population could be explained by means of the three associated risk factors mentioned above. This evidence may become changed when other circumstances, moments and places are involved in children having the same characteristics.