Miracle-dz/UniFAR-FTUs huggingface dataset:
Resource Footprint of a Manycast Protocol Implementation on Multiple Mobile Platforms

Wireless communication is becoming the dominant form of communication and ad hoc wireless connections are posed to play a role in disaster area networks. However, research efforts on wireless ad hoc communication protocols do not pay enough attention to measurable and reproducible indications of the mobile footprint including power consumption. Protocols and applications are initially designed and studied in a simulation environment and are hard to test in in-field experiments. In this work we report a multi-platform implementation of Random-Walk Gossip, a many cast protocol designed for message dissemination in disaster areas. Our work is focused in studying the resource footprint and its impact on performance on commercially available devices. We show both how different aspects of the protocol contributes to the footprint and how this in turn affects the performance. The methodologies used here can be applied to other protocols and applications, aiding in future optimisations.
The Perceived Value and Utilization of Occupational Therapy Models in the United States

This study investigated United States (U.S.) occupational therapy (OT) practitioners’ perceived value and utilization of OT models in practice. In addition, this research explored correlations that might impact practitioner value and choice of models as related to entry-level OT educational program, practice setting, and frequency of model utilization. The study utilized a cross-sectional research design. A convenience sample of 219 OT practitioners completed an 18-question online survey capturing participant demographics, perceived value, and utilization of models. Practitioners indicated they used models (79.45%, n = 174) in practice with 77.63% (n = 170) reporting they somewhat or strongly agreed that models were valuable to their practice. The greater the practitioner’s perceived value of models, the more often the person used models in practice (rs = . 575, p
Bacterial Induction of Beta Interferon in Mice Is a Function of the Lipopolysaccharide Component

ABSTRACT We investigated the reason for the inability of lipopolysaccharide (LPS)-resistant (Lps-defective [Lpsd]) C57BL/10ScCr mice to produce beta interferon (IFN-β) when stimulated with bacteria. For this purpose, the IFN-β and other macrophage cytokine responses induced by LPS and several killed gram-negative and gram-positive bacteria in LPS-sensitive (Lps-normal [Lpsn]; C57BL/10ScSn and BALB/c) and Lpsd (C57BL/10ScCr and BALB/c/l) mice in vitro and in vivo were investigated on the mRNA and protein levels. In addition, double-stranded RNA (dsRNA) was used as a nonbacterial stimulus. LPS and all gram-negative bacteria employed induced IFN-β in the Lpsn mice but not in theLpsd mice. All gram-positive bacteria tested failed to induce significant amounts of IFN-β in all four of the mouse strains used. As expected, all other cytokines tested (tumor necrosis factor alpha, interleukin 1α [IL-1α], IL-6, and IL-10) were differentially induced by gram-negative and gram-positive bacteria. Stimulation with dsRNA induced IFN-β and all other cytokines mentioned above in all mouse strains, regardless of their LPS sensitivities. The results suggest strongly that LPS is the only bacterial component capable of inducing IFN-β in significant amounts that are readily detectable under the conditions used in this study. Consequently, in mice, IFN-β is inducible only by gram-negative bacteria, but not in C57BL/10ScCr or other LPS-resistant mice.
Parent-of-origin effects in SOX2 anophthalmia syndrome

Purpose Sex determining region Y (SRY)-box 2 (SOX2) anophthalmia syndrome is an autosomal dominant disorder manifesting as severe developmental eye malformations associated with brain, esophageal, genital, and kidney abnormalities. The syndrome is usually caused by de novo mutations or deletions in the transcription factor SOX2. To investigate any potential parental susceptibility factors, we set out to determine the parent of origin of the mutations or deletions, and following this, to determine if birth order or parental age were significant factors, as well as whether mutation susceptibility was related to any sequence variants in cis with the mutant allele. Methods We analyzed 23 cases of de novo disease to determine the parental origin of SOX2 mutations and deletions using informative single nucleotide polymorphisms and a molecular haplotyping approach. We examined parental ages for SOX2 mutation and deletion cases, compared these with the general population, and adjusted for birth order. Results Although the majority of subjects had mutations or deletions that arose in the paternal germline (5/7 mutation and 5/8 deletion cases), there was no significant paternal bias for new mutations (binomial test, p=0.16) or deletions (binomial test, p=0.22). For both mutation and deletion cases, there was no significant association between any single nucleotide polymorphism allele and the mutant chromosome (p>0.05). Parents of the subjects with mutations were on average older at the birth of the affected child than the general population by 3.8 years (p=0.05) for mothers and 3.3 years (p=0.66) for fathers. Parents of the subjects with deletions were on average younger than the general population by 3.0 years (p=0.17) for mothers and 2.1 years (p=0.19) for fathers. Combining these data, the difference in pattern of parental age between the subjects with deletions and mutations was evident, with a difference of 6.5 years for mothers (p=0.05) and 5.0 years for fathers (p=0.22), with the mothers and fathers of subjects with mutations being older than the mothers and fathers of subjects with deletions. We observed that 14 of the 23 (61%) affected children were the first-born child to their mother, with 10/15 of the mutation cases (66%) and 4/8 deletion cases (50%) being first born. This is in comparison to 35% of births with isolated congenital anomalies overall who are first born (p=0.008). Conclusions Sporadic SOX2 mutations and deletions arose in both the male and female germlines. In keeping with several genetic disorders, we found that SOX2 mutations were associated with older parental age and the difference was statistically significant for mothers (p=0.05), whereas, although not statistically significant, SOX2 deletion cases had younger parents. With the current sample size, there was no evidence that sequence variants in cis surrounding SOX2 confer susceptibility to either mutations or deletions.
Modified quantitative insulin sensitivity check index is better correlated to hyperinsulinemic glucose clamp than other fasting-based index of insulin sensitivity in different insulin-resistant states.

Fasting-based index estimates of insulin sensitivity were compared with euglycemic hyperinsulinemic clamp (IS clamp) measurements in 148 subjects: normal controls (n = 46), and obese (n = 12), polycystic ovary syndrome (n = 16), first-degree relatives of type 2 diabetic (n = 17), impaired glucose tolerance (n = 28), and type 2 diabetic (n = 29) patients. The fasting-based indexes tested included log homeostasis model assessment (HOMA), the quantitative insulin sensitivity check index (QUICKI), the revised QUICKI, and a new revised QUICKI using fasting plasma glycerol. In the population studied, at 40 mU/m(2). min (n = 30) revised QUICKI (r = 0.86; P < 0.0001) and QUICKI-glycerol (r = 0.87; P < 0.0001) gave higher correlations with the IS clamp than QUICKI and log HOMA (r = 0.78 and r = -0.78; P < 0.001). For subjects tested at 75 mU/m(2). min (n = 118), comparable correlations were found for all indexes (r > 0.80; P < 0.0001). When studied in subgroups, revised QUICKI and QUICKI-glycerol give significantly higher correlations with the IS clamp than other indexes for lean control subjects studied at 40mU/m(2). min and impaired glucose tolerance subjects. We confirmed, in a large patient population with a wide range of insulin sensitivities, that no single test is superior in all groups of patients. However, QUICKI and revised QUICKI are good indexes that offer correlations similar to or higher than values obtained with log HOMA. Such indexes are simple tools to estimate insulin sensitivity appropriate for epidemiological studies.
N-(4-Chlorophenyl)-N′-(4-methylphenyl)succinamide

The asymmetric unit of the title compound, C17H17ClN2O2, contains one half-molecule with a center of symmetry at the mid-point of the central C—C bond. The dihedral angle between the benzene ring and the adjacent NH—C(O)—CH2 group is 39.9 (1)°. The methyl and Cl groups are disordered with respect to the para-positions of the benzene ring, with site-occupation factors of 0.5 each. In the crystal, intermolecular N—H⋯O hydrogen bonds link the molecules into chains parallel to the baxis.
Improving Java performance using hardware translation

State of the art Java Virtual Machines with Just-In-Time (JIT) compilers make use of advanced compiler techniques, run-time profiling and adaptive compilation to improve performance. However, these techniques for alleviating performance bottlenecks are more effective in long running workloads, such as server applications. Short running Java programs, or client workloads, spend a large fraction of their execution time in compilation instead of useful execution when run using JIT compilers. In short running Java programs, the benefits of runtime translation do not compensate for the overhead. We propose using hardware support to perform efficient Java translation coupled with a light weight run time environment. The additional hardware performs the translation of Java bytecodes to native code, thus eliminating much of the overhead of software translation. A translate d code buffer is used to hold the translated code, enabling reuse at the byte code level. The proposed hardware can be used in any general purpose processor without degrading performance of native code. The proposed technique is extremely effective for short running client workloads. A performance improvement of 2.8 times to 7.7 times over a software interpreter is achieved. When compared to a JIT compiler all SPECjvm98 benchmarks except one show a performance improvement ranging from. 2.7 times to 5.0 times. A performance degradation (0.58 times) is observed for one benchmark which is long running. Allowing hardware translation to perform optimizations similar to JIT compilers and Java processors will execute long running programs more efficiently and provide speedups similar to that of client workloads.
Unbiased Concurrent Evaluation on a Budget

Eliciting expert judgments for evaluating the performance of structured prediction systems (e.g., search engines, recommender systems) is labor-intensive and costly. This raises the question of how to get high-quality performance estimates given a relatively small budget of judgments. In this paper, we provide theoretically justified – yet highly practical and efficient – methods for selecting a subset of items to judge, addressing four commonly encountered evaluation scenarios: estimating the performance of a single system, comparing a system to a benchmark system, and estimating the relative and absolute performances of k systems. Our approach is based on designing effective importance sampling estimators that give provably unbiased performance estimates and that can re-use previously collected judgments. To this effect, we exploit the fact that many performance metrics of interest can be expressed as an expectation and derive theoretically optimal importance sampling distributions for estimating this expected value. We empirically demonstrate the effectiveness of our framework, showing that it eliminates the bias inherent in deterministic selection strategies (e.g. the pooling method) and that it can drastically reduce the number of judgments necessary compared to naive sampling approaches.
High Performance Motor Drive Technologies for Hybrid Vehicles

In this paper, latest motor drive technologies used for hybrid vehicles (HV), which are high output motor control and variable voltage system, will be introduced. Authors have researched and developed motor drive technologies through development of hybrid vehicles, which has been put into practical use to production vehicle. The developed motor drive system has the features of high efficiency, high power/weight ratio, and low-cost.
Paxillin expression levels are correlated with clinical stage and metastasis in salivary adenoid cystic carcinoma.

AIMS To investigate the relationship between paxillin expression and clinicopathological features and metastasis in salivary adenoid cystic carcinoma (SACC). METHODS A total of 47 SACC were assessed histochemically for paxillin expression. Paxillin immunoreactivity was compared with histological type, clinical stage and distant metastasis. RESULTS Paxillin expression was identified in 57.45% of SACC as cytoplasmic staining and the expression was correlated with distant metastasis and clinical stage (P < 0.05), but not with histological type. CONCLUSIONS Our observations indicate that paxillin expression is upregulated in SACC. High expression of paxillin was correlated with a more advanced stage and metastasis in SACC, suggesting that paxillin is a disease marker in advanced SACC and SACC with distant metastasis, and, consequently, may have value as a therapeutic target for SACC.
Maximum Power Point Tracking of Wireless Power Transfer at Midrange Operation

In this paper, Wireless Power Transfer (WPT) is investigated into the midrange operation considering the 65 cm distance where the power transfer capability is still possible due to the optimum impedance matching. Load side and source side impedance matching network are established and an optimum coupling is found and varied in each of the distance to achieve maximum power transferability. A comparison is done to validate the mathematical explanation with proper physical experiment and measured data confirmed the improvement of +3dB at 60 cm distance between the load and resonator coil.
Soil respiration and nitrogen leaching decreased in grey alder (Alnus incana (L.) Moench) coppice after clear-cut

ABSTRACT Grey alder (Alnus incana) is a highly productive indigenous tree species, potential for short-rotation forestry in the Baltic and Nordic countries. The aim of the study was to investigate the development of a new forest generation, as well as the nitrogen (N) and carbon (C) storages and fluxes in a grey alder regenerating coppice (COP) after clear-cut and in an adjacent unharvested 21-year-old stand (MAT), which had reached its bulk maturity. The regeneration of COP was rapid and 5 years after clear-cut, stem mass was 6.4 t ha−1. The nitrogen demand of the aboveground part of the 5-year-old COP trees was estimated to be roughly half of the corresponding value for MAT, depending mostly on leaf production. The annual N leaching flux in MAT was in the range of 16–29 kg ha−1, the corresponding values for COP were roughly half of that. Net nitrogen mineralization did not differ significantly between MAT (117 kg ha−1) and COP (129 kg ha−1). For the soil respiration study, a 32-year-old grey alder stand growing at a similar site was included; soil respiration was significantly higher in MAT compared to COP in all study years in both studied stands.
Real-Time Big Data Processing Framework: Challenges and Solutions

Data type and amount in human society is growing in amazing speed which is caused by emerging new services as cloud computing, internet of things and location-based services, the era of big data has arrived. As data has been fundamental resource, how to manage and utilize big data better has attracted much attention. Especially, with the development of internet of things, how to processing large amount real-time data has become a great challenge in research and applications. Recently, cloud computing technology has attracted much attention with high-performance, but how to use cloud computing technology for large-scale real-time data processing has not been studied. This paper studied the challenges of big data firstly and concludes all these challenges into six iss ues. In order to improve the performance of real-time processing of large data, this paper builds a kind of real-time big data processi ng (RTDP) architecture based on the cloud computing technology and then proposed the four layers of the architecture, and hierarc hical computing model. This paper proposed a multi-level storage model and the LMA-based application deployment method to meet the real-time and heterogeneity requirements of RTDP system. We use DSMS, CEP, batch-based MapReduce and other processing mode and FPGA, GPU, CPU, ASIC technologies differently to processing the data at the terminal of data collection. We structured the dat a and then upload to the cloud server and MapReduce the data combined with the powerful computing capabilities cloud architecture. This paper points out the general framework for future RTDP system and calculation methods, is currently the general method RTDP system design.
Preliminary Observations on Abnormalities of Membrane Structure and Function in Essential Hypertension

To test the hypothesis that structural abnormalities exist in the cell membrane in persons with essential hypertension and that these abnormalities affect membrane-related cellular functions, we examined several membrane-dependent phenomena and membrane lipid composition in the blood cells of subjects with essential hypertension. We analyzed platelet aggregability, membrane fluidity, membrane fatty acid composition, and erythrocyte deforinability in four normolipidemic subjects with untreated essential hypertension and in five age-matched normotensive controls. As compared with the controls, the subjects with essential hypertension had platelets that aggregated at lower concentrations of adenosine 5-diphosphate, platelet membranes that were less fluid, and erythrocytes that were more deformable. Lipid analysis of the membranes of platelets from the two study groups showed that although the cholesterol content was identical, the membranes from the essential hypertension group contained significantly less linoleic acid (18:2) than did those from the normotensive controls. Given the known effects of c/s-unsaturated fatty acyl composition on membrane fluidity and membrane-related cellular functions, these data suggest that one factor contributing to essential hypertension is an inherent structural membrane abnormality that alters the physical and functional properties of the cell membrane.
Complete Francis Turbine Flow SimulationAt Derbendikan Power Station

This paper presents the results of simulations of the complete three-dimensional fluid flow through the Spiral Casing, Stay Vane, Guide Vane, and then through the Francis turbine runner of the Derbendikan power station. To investigate the flow in the Francis turbine and also to identify the loads acting on the turbine blades, a three-dimensional model was prepared according to specifications provided. The results show that the maximum absolute pressure of 4.4x10 Pa is reached at the leading edge of the turbine runner and the maximum tangential velocity reaches 33 m/s in the turbine runner.
Real-time Characterization of Antibody Binding to Receptors on Living Immune Cells

Understanding molecular interactions on immune cells is crucial for drug development to treat cancer and autoimmune diseases. When characterizing molecular interactions, the use of a relevant living model system is important, as processes such as receptor oligomerization and clustering can influence binding patterns. We developed a protocol to enable time-resolved analysis of ligand binding to receptors on living suspension cells. Different suspension cell lines and weakly adhering cells were tethered to Petri dishes with the help of a biomolecular anchor molecule, and antibody binding was analyzed using LigandTracer. The protocol and assay described in this report were used to characterize interactions involving eight cell lines. Experiments were successfully conducted in three different laboratories, demonstrating the robustness of the protocol. For various antibodies, affinities and kinetic rate constants were obtained for binding to CD20 on both Daudi and Ramos B-cells, the T-cell co-receptor CD3 on Jurkat cells, and the Fcγ receptor CD32 on transfected HEK293 cells, respectively. Analyzing the binding of Rituximab to B-cells resulted in an affinity of 0.7–0.9 nM, which is similar to values reported previously for living B-cells. However, we observed a heterogeneous behavior for Rituximab interacting with B-cells, which to our knowledge has not been described previously. The understanding of complex interactions will be facilitated with the possibility to characterize binding processes in real-time on living immune cells. This provides the chance to broaden the understanding of how binding kinetics relate to biological function.
Individual differences in the influence of mental imagery on conscious perception

Mental imagery and visual perception rely on similar neural mechanisms, but the function of this overlap remains unclear. One idea is that imagery can influence perception. Previous research has shown that imagining a stimulus prior to binocular presentation of rivalling stimuli increases the chance of perceiving the imagined stimulus. In this study we investigated how this effect interacts with bottom-up sensory input by comparing psychometric response curves for congruent and incongruent imagery in humans. A Bayesian hierarchical model was used, allowing us to simultaneously study group-level effects as well as effects for individual participants. We found strong effects of both imagery as well as its interaction with sensory evidence within individual participants. However, the direction of these effects were highly variable between individuals, leading to weak effects at the group level. This highlights the heterogeneity of conscious perception and emphasizes the need for individualized investigation of such complex cognitive processes.
A spectral factorization approach to pseudo-QMF design

A novel approach to the design of M-channel pseudo-quadrature mirror filter (QMF) banks is presented. In this approach, the prototype filter is obtained as a spectral factor of a 2M/sup th/ band filter. This completely eliminates the need for optimization, whereas in conventional pseudo-QMF designs the main computational effort is in optimization of the prototype. The aliasing cancellation constraint is derived such that all the significant aliasing terms are canceled. The overall transfer function of the analysis/synthesis system has an approximately flat magnitude response in the frequency region epsilon <or= omega <or=( pi - epsilon ), where epsilon depends on the transition bandwidth of the prototype. A design example is included. <<ETX>>