Miracle-dz/UniFAR-FTUs huggingface dataset:
Enhanced Noxim simulator for performance evaluation of network on chip topologies

Analysis of topologies requires a complete performance evaluation of topology based on the metrics like latency, throughput and energy. In network on chip (NoC) based system, network metrics decide the efficiency of the system rather than its physical parameters. In the present design, complete performance evaluation of different regular topologies is carried out. The network simulation is performed on Noxim, which is modified to perform simulation for different regular topologies such as torus and twisted torus. A comprehensible analysis based on metrics such as hop count, path diversity and degree as well as other network parameters is provided along with the graphical analysis of the network parameters.
Synchrotron and Synchrotron Self-Compton Emission and the Blast-Wave Model of Gamma-Ray Bursts

We investigate the dynamics and radiation from a relativistic blast wave that decelerates as it sweeps up ambient matter. The bulk kinetic energy of the blast-wave shell is converted into internal energy by the process of accreting external matter. If it takes the form of nonthermal electrons and magnetic fields, then this internal energy will be emitted as synchrotron and synchrotron self-Compton radiation. We perform analytic and numerical calculations for the deceleration and radiative processes and present time-resolved spectra throughout the evolution of the blast wave. We also examine the dependence of the burst spectra and light curves on various parameters describing the magnetic field and nonthermal electron distributions. We find that for bursts such as GRB 910503, GRB 910601, and GRB 910814, the spectral shapes of the prompt gamma-ray emission at the peaks in νFν strongly constrain the magnetic fields in these bursts to be well below (≲10-2) the equipartition values. These calculations are also considered in the context of the afterglow emission from the recently detected gamma-ray burst counterparts.
A Controlled Study of Tuberculosis Diagnosis in HIV-Infected and Uninfected Children in Peru

Background Diagnosing tuberculosis in children is challenging because specimens are difficult to obtain and contain low tuberculosis concentrations, especially with HIV-coinfection. Few studies included well-controls so test specificities are poorly defined. We studied tuberculosis diagnosis in 525 children with and without HIV-infection. Methods and Findings ‘Cases’ were children with suspected pulmonary tuberculosis (n = 209 HIV-negative; n = 81 HIV-positive) and asymptomatic ‘well-control’ children (n = 200 HIV-negative; n = 35 HIV-positive). Specimens (n = 2422) were gastric aspirates, nasopharyngeal aspirates and stools analyzed by a total of 9688 tests. All specimens were tested with an in-house hemi-nested IS6110 PCR that took <24 hours. False-positive PCR in well-controls were more frequent in HIV-infection (P≤0.01): 17% (6/35) HIV-positive well-controls versus 5.5% (11/200) HIV-negative well-controls; caused by 6.7% (7/104) versus 1.8% (11/599) of their specimens, respectively. 6.7% (116/1719) specimens from 25% (72/290) cases were PCR-positive, similar (P>0.2) for HIV-positive versus HIV-negative cases. All specimens were also tested with auramine acid-fast microscopy, microscopic-observation drug-susceptibility (MODS) liquid culture, and Lowenstein-Jensen solid culture that took ≤6 weeks and had 100% specificity (all 2112 tests on 704 specimens from 235 well-controls were negative). Microscopy-positivity was rare (0.21%, 5/2422 specimens) and all microscopy-positive specimens were culture-positive. Culture-positivity was less frequent (P≤0.01) in HIV-infection: 1.2% (1/81) HIV-positive cases versus 11% (22/209) HIV-negative cases; caused by 0.42% (2/481) versus 4.7% (58/1235) of their specimens, respectively. Conclusions In HIV-positive children with suspected tuberculosis, diagnostic yield was so low that 1458 microscopy and culture tests were done per case confirmed and even in children with culture-proven tuberculosis most tests and specimens were false-negative; whereas PCR was so prone to false-positives that PCR-positivity was as likely in specimens from well-controls as suspected-tuberculosis cases. This demonstrates the importance of control participants in diagnostic test evaluation and that even extensive laboratory testing only rarely contributed to the care of children with suspected TB. Trial Registration This study did not meet Peruvian and some other international criteria for a clinical trial but was registered with the ClinicalTrials.gov registry: ClinicalTrials.gov NCT00054769
Performance evaluation of VSQ: a fair MAC scheme for packet ring networks

Packet ring networks are increasingly being used to support data services in metropolitan areas. The IEEE 802.17 resilient packet ring (RPR) standard is a new technology for metro packet rings. However, there are some performance deficiencies associated with RPR, such as large access delay, throughput loss and slow convergence. In our previous work, we proposed a fair medium access control (MAC) scheme called virtual source queuing (VSQ) for packet ring networks. We also designed an effective congestion control scheme called one-hop-backpressure (OHB) to ensure lossless transit paths for VSQ. OHB exploits the source information and implicitly control the input rate of the sources that send excessive traffic. In this paper, we provide detailed performance evaluation of VSQ in comparison with various MAC schemes. Our simulation and analysis results demonstrate that VSQ requires less transit buffer occupancy and variance to ensure lossless transit paths than RPR does. We also conduct complexity comparisons among different MAC schemes. The comparisons show that VSQ is a simple and efficient MAC scheme for metro packet ring networks
Genomic Instability: A Stronger Prognostic Marker Than Proliferation for Early Stage Luminal Breast Carcinomas

Background The accurate prognosis definition to tailor treatment for early luminal invasive breast carcinoma patients remains challenging. Materials and Methods Two hundred fourteen early luminal breast carcinomas were genotyped with single nucleotide polymorphisms (SNPs) array to determine the number of chromosomal breakpoints as a marker of genomic instability. Proliferation was assessed by KI67 (immunohistochemistry) and genomic grade index (transcriptomic analysis). IHC3 (IHC4 score for HER2 negative tumors) was also determined. Results In the training set (109 cases), the optimal cut-off was 34 breakpoints with a specificity of 0.94 and a sensitivity of 0.57 (Area under the curve (AUC): 0.81[0.71; 0.91]). In the validation set (105 cases), the outcome of patients with > 34 breakpoints (11 events / 22 patients) was poorer (logrank test p < 0.001; Relative Risk (RR): 3.7 [1.73; 7.92]), than that of patients with < 34 breakpoints (19 events / 83 patients). Whereas genomic grade and KI67 had a significant prognostic value in univariate analysis in contrast to IHC3 that failed to have a statistical significant prognostic value in this series, the number of breakpoints remained the only significant parameter predictive of outcome (RR: 3.47, Confidence Interval (CI [1.29; 9.31], p = 0.014)) in multivariate analysis . Conclusion Genomic instability, defined herein as a high number of chromosomal breakpoints, in early stage luminal breast carcinoma is a stronger prognostic marker than proliferation.
The meaning-making affordances of composing print and digital graphic narratives

ABSTRACT A classroom-based study with eight- and nine-year-old students included the participants having many opportunities to engage with multimodal print and digital texts, and various technological tools. The data presented in this article focus on one of the specific purposes of the research: to investigate students’ opinions of the affordances of designing print and digital graphic narratives. The content analysis of the students’ reflections about working with a software programme to compose a multimodal ensemble in the medium of comics revealed evidence of critical thinking as they analysed and critiqued the possibilities and constraints for meaning-making. The conclusion features a consideration of the importance of students and teachers developing metalevel knowledge about and a critical stance toward the meaning-making affordances of all texts and compositional tools and devices.
Automatic Music Stretching Resistance Classification Using Audio Features and Genres

Music stretching resistance (MSR) is a fresh but important concept in audio signal processing, which characterizes the ability of a music piece to be stretched in time (compressed or elongated) without objectionable perceptual artifacts. It has the potential to be highly demanded in various multimedia applications like music resizing, audio editing and multimedia integration, but there is almost no prior knowledge about this property of music in literature. In this letter, the task of MSR is formulated for the first time, and an MSR classification method that employs metric learning on audio features and genres is also proposed. It attempts to automate what human acceptable time-stretching rate range of music should be. The proposed method outperforms the reference classification methods in accuracy in the comparative experiments.
A Matrix-Based Visualization for Exploring Dynamic Compound Digraphs

We introduce a matrix-based visualization technique for exploring time-varying directed and weighted graphs. Two overview representations are shown: one for the time-aggregated relations with attached quantitative weighted attributes and one for the results of an automatic dynamic pattern identification algorithm, i.e., relations accompanied by categorical attributes. Apart from a dynamic edge pattern categorization, our tool can also compute graph-specific properties---such as shortest paths or the existence of cliques---and highlight their evolution over time. The visualization method is complemented by interaction techniques that allow the user to navigate, explore, and browse the data, based on the Visual Information Seeking Mantra---overview first, zoom and filter, then details-on-demand. If an additional hierarchical organization of the vertices is available, this is attached to the matrix by vertical and horizontal layered icicle plots allowing one to explore the data on different levels of hierarchical granularity. The usefulness of the tool is demonstrated by applying it to time-varying migration data in the hierarchically structured world.
A multi agent recommender system that utilises consumer reviews in its recommendations

Consumer reviews, opinions and shared experiences in the use of a product form a powerful source of information about consumer preferences that can be used for making recommendations. A novel approach, which utilises this valuable information sources first time to create recommendations in recommender agents was recently developed by Aciar et al. (2007). This paper presents a general framework of this approach. The proposed approach is demonstrated using digital camera reviews as an example.
The two dimensions of an architecture

A two-dimensional view on software architectures is introduced. One of the dimensions is the implementation-oriented view based on component structure, and the other is de ned by abstractions and logic of collaboration. We argue that unless the view based on collaboration is rigorously taken into account in early phases of the development, architectures will be based on informal expectations and implementation bias. This bias may then blur the logic of the speci cation, whereas an adequate use of abstractions of collaboration as basis for architecture will eliminate super uous di culties in design and veri cation.
“Olá, my name is Ana”: A study on Brazilians interacting with a receptionist robot

In the near future, robots are expected to perform assistive tasks and do different kind of jobs. In particular, humanoid robots are possible candidates for being used as helpers in activities of daily living. One possible employment is working as a receptionist, providing useful indications to visitors in a public office. The design of how robots could look like is a matter of growing importance, as it is important to create a look that poses no uncanny valley effects on the human user and that is appropriate to potentially serve in different job areas in human society. In this paper we want to describe the study on anthropomorphism of a receptionist robot. We invited Brazilian people with different education levels to interact with two variations of a receptionist robot, different in physical appearance as well as in the sound of the voice. In one case, the appearance was a conversational agent made with computer graphics, in the other, a real humanoid robot. Results gathered from surveys and comments of the participants provide useful directions to design a receptionist robot and insights on the effect of digital divide on anthropomorphism.
A study of computer-supported user interface evaluation using maximal repeating pattern analysis

Maximal repeating pattern (MRP) analysis is a recently developed user interface evaluation technique that uses an algorithm to analyze transcripts of user sessions by detecting repeated user actions. Encouraged by results of an initial study of the MRP technique, we conducted a study in which we evaluated a simple prototype interface using both the MRP technique and observation. Interface problems found by observation were also found by MRP analysis. Although the MRP algorithm produced large amounts of data that an interface evaluator had to analyze, we found that by mapping raw user inputs in the transcripts into more abstract classes via prefiltering, we could perform more useful MRP analyses.
Engineering of a Genetically Encodable Fluorescent Voltage Sensor Exploiting Fast Ci-VSP Voltage-Sensing Movements

Ci-VSP contains a voltage-sensing domain (VSD) homologous to that of voltage-gated potassium channels. Using charge displacement (‘gating’ current) measurements we show that voltage-sensing movements of this VSD can occur within 1 ms in mammalian membranes. Our analysis lead to development of a genetically encodable fluorescent protein voltage sensor (VSFP) in which the fast, voltage-dependent conformational changes of the Ci-VSP voltage sensor are transduced to similarly fast fluorescence read-outs.
Metal Abundances of Red Clump Stars in Open Clusters. I. NGC 6819

We present an analysis of high-dispersion spectra (R ∼ 40,000) of three red clump stars in the old open cluster NGC 6819. The spectra were obtained with SARG, the high-dispersion spectrograph of the Telescopio Nazionale Galileo. The spectra were analyzed using both equivalent widths measured with an automatic procedure and comparisons with synthetic spectra. NGC 6819 is found to be slightly metal-rich ([Fe/H] = +0.09 ± 0.03, internal error); there are no previous high-resolution studies to compare. Most element-to-element abundance ratios are close to solar; we find a slight excess of Si and a significant Na overabundance. Our spectra can also be used to derive the interstellar reddening toward the cluster by comparing the observed colors with those expected from line excitation: we derive E(B-V) = 0.14 ± 0.04, in agreement with the most recent estimate for this cluster.
Investigation of Hybrid Silicon-Nitride/Polymer Waveguides for Second-Harmonic Generation

We propose a hybrid silicon-nitride (Si3N4 or SiN for short)/nonlinear polymer waveguide to achieve second-harmonic generation of an input 1550 nm signal by modal phase-matching between zero-order spatial mode at 1550 nm and second-order mode at 775 nm. We explore and optimize two cases, single channel waveguide and slot waveguide, by varying the waveguide dimensions. For TE polarized light, the optimum slot waveguide exhibits an effective interaction area Aeff of about 16 μm2, which is an order-of-magnitude improvement over the single channel waveguide and can translate to a high value of effective nonlinearity. We also show that the optimum slot waveguide geometry is robust with respect to fabrication uncertainties and bending effects.
The Neurostructural Phenotypes of CACNA1C rs1006737 in Adolescents with Bipolar Disorder and Healthy Controls of Caucasian Race

Background: CACNA1C rs1006737 has been implicated in structural brain differences in adults with bipolar disorder (BD) and/or healthy controls (HCs). No prior study has examined associations between rs1006737 and brain structure in adolescents. Methods: Seventy-one adolescents (14-20 years; 38BD, 33HC) underwent 3-Tesla Magnetic Resonance Imaging (MRI). ROI and whole-brain vertex-wise analyses examined cortical and subcortical volume, surface area (SA), and/or thickness. General linear models included main effects of diagnosis and rs1006737, and an interaction term, controlling for age, sex, and total intracranial volume. Results: Vertex-wise analysis found significant diagnosis-by-rs1006737 interactions for prefrontal and occipital brain structure Main effects of rs1006737 were found on anterior cingulate cortex SA from ROI analysis, and occipital SA from vertex-wise analysis. Conclusion: The current study identified neurostructural intermediate phenotypes relevant to the impact of CACNA1C rs1006737 on adolescent BD. Further investigation is warranted into the relevance of rs1006737 associations with BD-specific elevations in regional SA.
Testing high-energy factorization beyond the next-to-leading-logarithmic accuracy

By taking the high-energy limit of the two-loop and the three-loop four-point amplitudes in the maximally supersymmetric N = 4 Yang-Mills theory (MSYM), we test the validity of the loop expansion of the high-energy amplitude, beyond the next-to-leading-logarithmic (NLL) accuracy. We compute the three-loop Regge trajectory, and the two-loop and three-loop coefficient functions. These quantities are relevant for the BFKL evolution beyond NLL, as well as building MSYM two-loop and three-loop amplitudes with many legs in the high-energy limit, which in turn may be used as a powerful check of the evaluation of the corresponding exact amplitudes.
Longitudinal Patterns of Juvenile And Adult Offending in Youth in the Mental Health System

Introduction Studies have shown that, compared to other youth within their same social class, a higher proportion of youth with serious emotional disturbance (SED) are arrested during adolescence and young adulthood (e. Most of these studies have examined youth from mental health or special education services. Knowledge about criminal justice (CJ) involvement among these particular youth is fairly superficial, focusing primarily on arrest rates, charge types, and a limited range of risk factors. Few have directly employed comparison groups (Vander Stoep, et al, 1997; 2000). CJ involvement has generally been classified as a dichotomy (arrested/not), limiting our understanding of patterns of criminal behavior. Cross-sectional designs have been employed, limiting our knowledge of temporal sequence. Several longitudinal studies of youth in the general population have identified diverse patterns of CJ involvement across age (e. Trajectory methodology is new in criminology and characterizes subgroups of individuals with different developmental criminal trajectories (e. This method has several advantages. Different periods of greatest risk can be identified. Characteristics of individuals within each cluster can be profiled. Individual and contextual maturational changes associated with arrest patterns can be explored. Trajectory typologies can be related to criminology theory. The present longitudinal study explores trajectory patterns of CJ involvement among youth who utilize the child mental health system in Massachusetts. Methods The present study examined the clinical charts and automated CJ records of 131 individuals who received intensive public mental health services from one agency in the greater Boston area and had reached the age of 25 by 12/31/00. Subjects. All individuals with birth years from 1968-1973, and who were sequentially discharged between 1988-1994 from the agency's adolescent day, residential, and hospital treatment programs, served as subjects. Thirty-eight individuals had clinical charts that were not informative. These individuals came from one hospital unit and were likely to have had such a brief stay that their charts were not prepared prior to discharge. Analyses of subject characteristics are based on clinical charts of the remaining 93 subjects. Over half of the subjects (56%) were male, a third were of minority race, and 47% were from single-parent households. The most common diagnoses were affective (50%), disruptive behavior (28%), anxiety (24%), personality (24%), substance abuse and dependence (20%), and psychotic (12%) disorders. Individuals averaged 3.1 (± 3.2) psychiatric hospitalizations. CJ Database. The CJ database records the type and disposition of all charges that have been arraigned in all non-federal courts …
Stochastic Simulation Research in Management Science

W the simulation department ofManagement Science was created in 1978 it ushered in an era of significant methodological advances in stochastic simulation. However, the foundation for the field—not just the work that has been published in Management Science—was provided by two papers published long before simulation had its own department in the journal. We will review the seminal papers of Conway, Johnson, and Maxwell (1959) and Conway (1963), and then trace their impact through eight award-winning papers that appeared much later in Management Science.
Persistent Storage of Ontology-Based Data with Integrity Constraints

Recently, a lot of approaches and systems were proposed to store the ontology-based data to the relational database. In this paper, we present a novel approach to store the ontology-based data with integrity constraints. Integrity constraint (IC) is a formula that checks whether all the necessary information has been explicitly provided. It can be added into ontology to guarantee the integrity of the ontology. A set of constraint axioms called IC-based axioms are proposed to represent the integrity constraints in the ontology and further store the ontology-based data in the relational database, which satisfy the integrity constraints. Through comparing with other existing approaches used in Semantic Web applications, the experiment shows that our approach is advanced to the traditional approaches.
Possible evidence of asymmetry in SN 2007rt, a type IIn supernova

An optical photometric and spectroscopic analysis of the slowly-evolving type IIn SN 2007rt is presented, covering a duration of 481 days after discovery. Its earliest spectrum, taken approximately 100 days after the explosion epoch, indicates the presence of a dense circumstellar medium, with which the supernova ejecta is interacting. This is supported by the slowly-evolving light curve. A notable feature in the spectrum of SN 2007rt is the presence of a broad He i 5875 line, not usually detected in type IIn supernovae. This may imply that the progenitor star has a high He/H ratio, having shed a significant portion of its hydrogen shell via mass-loss. An intermediate resolution spectrum reveals a narrow Hα P-Cygni profile, the absorption component of which has a width of 128 km s −1 . This slow velocity suggests that the progenitor of SN 2007rt recently underwent mass-loss with wind speeds comparable to the lower limits of those detected in luminous blue variables. Asymmetries in the line profiles of H and He at early phases bears some resemblance to double-peaked features observed in a number of Ib/c spectra. These asymmetries may be indicative of an asymmetric or bipolar outflow or alternatively dust formation in the fast expanding ejecta. In addition, the late time spectrum, at over 240 days post-explosion, shows clear evidence for the presence of newly formed dust.