Miracle-dz/UniFAR-FTUs huggingface dataset:
On certain pure sextic fields related to a problem of Hasse

An algebraic number ring is monogenic, or one-generated, if it has the form Z[α] for a single algebraic integer α. It is a problem of Hasse to characterize, whether an algebraic number ring is monogenic or not. In this note, we prove that if m is a square-free rational integer, m ≡ 1(mod 4) and m≢ ± 1(mod 9), then the pure sextic field L = Q(m6) is not monogenic. Our results are illustrated by examples.
Nutch : an Open-Source Platform for Web Search

Nutch is an open-source project providing both complete Web search software and a platform for the development of novel Web search methods. Nutch is built on a distributed storage and computing foundation, such that every operation scales to very large collections. Core algorithms crawl, parse and index Web-based data. Plugins extend functionality at various points, including network protocols, document formats, indexing schemas and query operators.
Objective Versus Perceived Walking Distances to Destinations

Judgments concerning features of environments do not always correspond accurately with objective measures of those same features. Moreover, perceived and objectively assessed environmental attributes, including proximity of destinations, may influence walking behavior in different ways. This study compares perceived and objectively assessed distance to several different destinations and examines whether correspondence between objective and perceived distance is influenced by age, gender, neighborhood walkability, and walking behavior. Distances to most destinations close to home are overestimated, whereas distances to those farther away are underestimated. Perceived and objective distances to certain types of destinations are differentially associated with walking behavior. Perceived environmental attributes do not consistently reflect objectively assessed attributes, and both appear to have differential effects on physical activity behavior.
Send Orders of Reprints at Reprints@benthamscience.net Benzene-poly-carboxylic Acids Complex with Cis-diammineplatinum (ii) Dichloride in the Treatment of Stage Iv Breast Cancer Patients

An anti-cancer agent containing benzene-poly-carboxylic acids complex with cis-diammineplatinum (II) dichloride (BP-C1) was developed to establish a low toxic and cost effective treatment of breast cancer. The study was aimed to investigate if BP-C1 could be given continuously without rest periods and to estimate Maximum Tolerated (MTD) and Minimum Efficient Dose (MED) in metastatic breast cancer (MBC) treatment. A non-randomized, multi-centre trial with 3-level Response Surface Pathway design was performed. Five MBC patients were included at each of the three design levels. BP-C1 was daily administrated intramuscularly during 32 days. The first five patients were given a cumulative dose of 0.64 mg/kg bodyweight. Based on the obtained results, the dose was increased /decreased for the next five patients in the next design level. The main variable was the National Cancer Institute Common Toxicity Criteria (NCI-CTC). Cumulative doses of 0.96 mg/kg or higher were defined as high-dose. One moderate and one mild increase in maximum NCI-CTC were found on 0.64 mg/kg, one mild increase occurred on 0.96 mg/kg and no changes were detected on 1.12 mg/kg. The Sum NCI-CTC increased (p=0.07) in the low-dose group, but reduced (p=0.09) in the high-dose group. In the high-dose group, 62.5% of the patients were classified as responders including one complete responder compared to 28.6% in the low-dose group. In conclusion, BP-C1 can safely be administrated continuously during 32 days. The MTD is larger than 1.12 mg/kg and MED estimated to 0.96 mg/kg.
“Who was Pietro Badoglio?” Towards a QA system for Italian History

This paper presents QUANDHO (QUestion ANswering Data for italian HistOry), an Italian question answering dataset created to cover a specific domain, i.e. the history of Italy in the first half of the XX century. The dataset includes questions manually classified and annotated with Lexical Answer Types, and a set of question-answer pairs. This resource, freely available for research purposes, has been used to retrain a domain independent question answering system so to improve its performances in the domain of interest. Ongoing experiments on the development of a question classifier and an automatic tagger of Lexical Answer Types are also presented.
A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum

Pex19p, a soluble cytoplasmic transport protein, is required for the traffic of the peroxisomal membrane proteins Pex3p and Pex15p from the endoplasmic reticulum (ER) to the peroxisome. We documented Pex15p traffic from the ER using a chimeric protein containing a C-terminal glycosylation acceptor peptide. Pex15Gp expressed in wild-type yeast cells is N-glycosylated and functions properly in the peroxisome. In contrast, pex19Δ-mutant cells accumulate the glycoprotein Pex15Gp in the ER. We developed a cell-free preperoxisomal vesicle-budding reaction in which Pex15Gp and Pex3p are packaged into small vesicles in the presence of cytosol, Pex19p, and ATP. Secretory vesicle budding (COPII) detected by the packaging of a SNARE protein (soluble N-ethylmaleimide-sensitive attachment protein receptor) occurs in the same incubation but does not depend on Pex19p. Conversely a dominant GTPase mutant Sar1p which inhibits COPII has no effect on Pex3p packaging. Pex15Gp and Pex3p budded vesicles sediment as low-buoyant-density membranes on a Nycodenz gradient and copurify by affinity isolation using native but not Triton X-100–treated budded vesicles. ER–peroxisome transport vesicles appear to rely on a novel budding mechanism requiring Pex19p and additional unknown factors.
Internet Engineering Task Force (ietf) Definition of Managed Objects for Ipv6 over Low-power Wireless Personal Area Networks (6lowpans)

This document defines a portion of the Management Information Base (MIB) for use with network management protocols in the Internet community. In particular, it defines objects for managing IPv6 over Low-Power Wireless Personal Area Networks (6LoWPANs). Information about the current status of this document, any errata, and how to provide feedback on it may be obtained at in effect on the date of publication of this document. Please review these documents carefully, as they describe your rights and restrictions with respect to this document. Code Components extracted from this document must include Simplified BSD License text as described in Section 4.e of the Trust Legal Provisions and are provided without warranty as described in the Simplified BSD License.
Particle swarm optimization based on Gaussian mutation and its application to wind farm micro-siting

In this paper, a particle swarm optimization algorithm with Gaussian mutations, denoted by GPSO, is proposed to solve constrained optimization problems. Two Gaussian mutation operators are employed to search the promising regions for better solutions. One operator is for the region between the personal best position and the global best one. The other operator is for the region around the global best position. The Gaussian mutations help the population jump out of local optima and find better solutions with more probability. The feasibility-based method compares the performance of different particles. Evaluated by three typical optimization problems, GPSO is more accurate, robust and efficient for locating global optima. The GPSO method is applied to a wind-farm micro-siting problem. Simulation results demonstrate that the power generation of the wind farm is further improved while the execution time is substantially reduced.
Placental Restriction Increases the Expression of Prostaglandin Endoperoxide G/H Synthase-2 and EP2 mRNA in the Fetal Sheep Kidney during Late Gestation

There is evidence that fetal growth restriction is associated with impaired nephrogenesis and reduced numbers of mature nephrons at birth. It has been proposed that such impairment of renal growth may contribute to increased blood pressure in later life. Although prostaglandins (PG) play a key role in kidney development, it is unknown whether a poor fetal substrate supply alters the synthesis or actions of PG within the fetal kidney. Using real-time reverse transcriptase PCR, we have measured the effect of chronic placental restriction (PR) on the renal expression of PG endoperoxide G/H synthase-2 (PGHS-2), PGE2 receptors EP2 and EP4, and renin mRNA in the sheep fetus in late gestation. Restriction of placental growth reduced fetal body weight (PR: 3.2 ± 0.2 kg, control: 4.8 ± 0.2 kg) and total kidney weight (PR: 19.7 ± 1.8 g, control: 25.1 ± 1.3 g). Mean fetal arterial Po2 was reduced by PR (PR: 15.03 ± 0.67 mm Hg, control: 21.3 ± 0.87 mm Hg). Renal PGHS-2 mRNA was increased in the PR group (PR: 2.26 ± 0.38, control: 1.20 ± 0.31) and was inversely related to mean fetal arterial Po2 in the PR and control groups [PGHS-2: −0.17 (Po2) + 4.69, r2 = 0.26]. PR also increased renal EP2 (PR: 1.57 + 0.24, control: 0.82 + 0.13) but not EP4 mRNA. Renin mRNA was directly related to renal EP2 [renin = 0.37 (EP2) + 0.97, r2 = 0.29] and EP4, [renin = 0.75 (EP4) + 0.44, r2 = 0.38] mRNA expression. Thus, the restriction of placental growth and associated chronic hypoxemia appear to increase the renal capacity to synthesize and respond to PG, which may play an important role in maintaining renin mRNA expression in the growth-restricted fetus.
Interference alignment with combined receivers for heterogeneous networks

We propose a novel combined receiver which applies zero forcing (ZF) to null the dominant interferers, followed by minimum-mean-square-error (MMSE) processing to reduce the effect of the remaining interference and noise. The receiver is used in conjunction with an interference alignment (IA) scheme in a multicell environment. Simulation results considering a range of interferer profiles show that the combined receiver outperforms an MMSE receiver, due to its ability to eliminate the dominant interferers. The complete nulling of many dominant interferers in a multi-user, multicell case requires a large number of receive antennas. If the antennas are closely located in a compact array, then spatial correlation is important and its impact on the IA scheme is also considered.
An Interactive Approach to Pose-Assisted and Appearance-based Segmentation of Humans

An interactive human segmentation approach is described. Given regions of interest provided by users, the approach iteratively estimates segmentation via a generalized EM algorithm. Specifically, it encodes both spatial and color information in a nonparametric kernel density estimator, and incorporates local MRF constraints and global pose inferences to propagate beliefs over image space iteratively to determine a coherent segmentation. This ensures the segmented humans resemble the shapes of human poses. Additionally, a layered occlusion model and a probabilistic occlusion reasoning method are proposed to handle segmentation of multiple humans in occlusion. The approach is tested on a wide variety of images containing single or multiple occluded humans, and the segmentation performance is evaluated quantitatively.
Statin inhibits hypoxia-induced endothelin-1 via accelerated degradation of HIF-1α in vascular smooth muscle cells.

AIMS Endothelin-1 (ET-1) contributes to the pathogenesis of cardiovascular diseases with multiple properties such as vasoconstriction. Human ET-1 gene expression is up-regulated by the transcription factor hypoxia-inducible factor-1 (HIF-1) through hypoxia response element (HRE). Although previous studies suggested that 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) alter HIF-1-related gene expression, it remained unclear whether statins modulate HIF-1-mediated ET-1 expression. Therefore, we investigated the effect of fluvastatin on hypoxia-induced human ET-1 expression in vascular smooth muscle cells (VSMC). METHODS AND RESULTS Hypoxia (1% O(2)), compared with the normoxic condition (21% O(2)), significantly induced the expression of preproET-1 mRNA, ET-1 protein, and ET-1 secretion in VSMC. Hypoxia induced a 2.3-fold increase in HRE-dependent ET-1 reporter gene activation. Under concentrations of 1 µmol/L or greater, fluvastatin attenuated the hypoxia-induced ET-1 gene expression through the accelerated ubiquitin/proteasome-dependent degradation of HIF-1α, thus consequently attenuating HIF-1α binding to the HRE of the ET-1 gene. These inhibitory effects of fluvastatin were cancelled by concomitant treatment with mevalonate, farnesyl pyrophosphate, or geranylgeranyl pyrophosphate, but not squalene. CONCLUSION The present study suggests that fluvastatin attenuates HIF-1-dependent ET-1 gene expression in conjunction with the stimulation of HIF-1α ubiquitin/proteasome-dependent degradation via isoprenoid-dependent mechanisms.
Development and Factor Analysis of the Teacher Job Satisfaction Questionnaire (TJSQ)

An instrument designed to measure teacher job satisfaction was developed using randomly selected elementary, junior high school, and senior high school teachers in New York City, Nassau, Suffolk, and Westchester Counties. Factor analysis was undertaken as an exploratory technique to help discover underlying factors and as a psychometric procedure for the development and refinement of the instrument (TJSQ). A terminal nine-factor orthogonal varimax solution was accepted using the criterion of Eigenvalues greater than or equal to unity. The internal consistency of the instrument was calculated (coefficient alpha) for each scale and for the total score (.93).
Sleep stage classification by non-contact vital signs indices using Doppler radar sensors

Disturbed sleep has become more common in recent years. To improve the quality of sleep, undergoing sleep observation has gained interest as a means to resolve possible problems. In this paper, we evaluate a non-restrictive and non-contact method for classifying real-time sleep stages and report on its potential applications. The proposed system measures heart rate (HR), heart rate variability (HRV), body movements, and respiratory signals of a sleeping person using two 24-GHz microwave radars placed beneath the mattress. We introduce a method that dynamically selects the window width of the moving average filter to extract the pulse waves from the radar output signals. The Pearson correlation coefficient between two HR measurements derived from the radars overnight, and the reference polysomnography was the average of 88.3% and the correlation coefficient for HRV parameters was the average of 71.2%. For identifying wake and sleep periods, the body-movement index reached sensitivity of 76.0%, and a specificity of 77.0% with 10 participants. Low-frequency (LF) components of HRV and the LF/HF ratio had a high degree of contribution and differed significantly across the three sleep stages (REM, LIGHT, and DEEP; p <; 0.01). In contrast, high-frequency (HF) components of HRV were not significantly different across the three sleep stages (p > 0.05). We applied a canonical discriminant analysis to identify wake or sleep periods and to classify the three sleep stages with leave-one-out cross validation. Classification accuracy was 66.4% for simply identifying wake and sleep, 57.1% for three stages (wake, REM, and NREM) and 34% for four stages (wake, REM, LIGHT, and DEEP). This is a novel system for measuring HRs, HRV, body movements, and respiratory intervals and for measuring high sensitivity pulse waves using two radar signals. It simplifies measurement of sleep stages and may be employed at nursing care facilities or by the general public to improve sleep quality.
A cross-cultural investigation of situational information security awareness programs

Purpose – The aim of this research is to make users aware of the importance surrounding the issue of security and security awareness while at the same time making educators as well as other individuals aware of the differing effects of cultural dimensions into the learning process.Design/methodology/approach – An inter-cultural study was conducted to investigate if users from the USA and Taiwan exposed to the same situational awareness learning would have different performance in those security awareness outcomes.Findings – The findings confirm that American users who received the situational learning outperformed those users who received the traditional face-to-face instruction. Taiwanese users did not perform significantly differently between these two treatments.Research limitations/implications – The study was only focused on two countries and therefore may limit its implications worldwide. But the study does show that global citizens also react differently to security awareness as would be expected due to differing cultures. Certainly, awareness of the risks and safeguards is the first line of defense that can be employed by any individual, but how individuals address these risks can be very dissimilar in different cultures. Therefore, the implications are apparent that the issue of security awareness should be studied from different cultural perspectives.Originality/value – This paper offers original findings and value into the investigation of whether or not situational security awareness training is culturally-bounded
A Subpixel Target Detection Approach to Hyperspectral Image Classification

Hyperspectral image classification faces various levels of difficulty due to the use of different types of hyperspectral image data. Recently, spectral–spatial approaches have been developed by jointly taking care of spectral and spatial information. This paper presents a completely different approach from a subpixel target detection view point. It implements four stage processes, a preprocessing stage, which uses band selection (BS) and nonlinear band expansion, referred to as BS-then-nonlinear expansion (BSNE), a detection stage, which implements constrained energy minimization (CEM) to produce subpixel target maps, and an iterative stage, which develops an iterative CEM (ICEM) by applying Gaussian filters to capture spatial information, and then feeding the Gaussian-filtered CEM-detection maps back to BSNE band images to reprocess CEM in an iterative manner. Finally, in the last stage Otsu’s method is applied to converting ICEM-detected real-valued maps to discrete values for classification. The entire process is called BSNE-ICEM. Experimental results demonstrate BSNE-ICEM, which has advantages over support vector machine-based approaches in many aspects, such as easy implementation, fewer parameters to be used, and better false classification and precision rates.
Personal uses and perceived social and economic effects of advertising in Bulgaria and Romania

Purpose - The objective of this paper is to uncover the underlying dimensions of, and examine the similarities and differences in, personal uses of advertising, perceived socio-economic effects of advertising, and consumer beliefs and attitudes toward advertising in Bulgaria and Romania. Moreover, it aims to identify the relative importance of the predictors of attitudes toward advertising in the two countries. Design/methodology/approach - The paper draws upon findings of previous research and theoretical developments by Bauer and Greyser, Sandage and Leckenby, and Pollay and Mittal. The study uses a stratified random sample of 947 face-to-face interviews with adult respondents from major urban areas in Bulgaria (507) and Romania (440). Variables are measured on multi-item scales as a typical application of the reflective indicator model. Findings - Results show that there are significant differences between Romanian and Bulgarian respondents in terms of their attitudes toward advertising. Romanians are more positive about advertising as an institution than the instruments of advertising. Romanians seem to accept the role of advertising in a free market economy, but have less confidence in advertising claims and techniques. Bulgarian respondents seem more sceptical toward advertising in general and are less enthusiastic about embracing the role of advertising as an institution. Moreover, Bulgarians are highly negative towards the instruments advertising uses to convey its messages to consumers. Research limitations/implications - The research findings reflect the views of urban dwellers and may not be generalisable to the wider population of the two countries. Interviewer bias was reduced by eliminating verbal or non-verbal cues to the respondents, and by the use of stratified random sampling. Practical implications - The paper suggests that the regulatory role of codes of advertising practice and industry regulating bodies should be enhanced, and their ability to protect consumers enforced. Marketing campaigns should be more inclusive to involve diverse social groups and reflect generally-accepted social norms. Originality/value - This study reveals that, while general attitudes toward advertising may be similar, attitudes toward the institution and instruments of advertising may differ even in countries with geographic proximity and low cultural distance. © Emerald Group Publishing Limited.
Active Online Multitask Learning

In this paper, we propose an online multitask learning framework where the weight vectors are updated in an adaptive fashion based on inter-task relatedness. Our work is in contrast with the earlier work on online multitask learning (Cavallanti et al., 2008) where the authors use a fixed interaction matrix of tasks to derive (fixed) update rules for all the tasks. In this work, we propose to update this interaction matrix itself in an adaptive fashion so that the weight vector updates are no longer fixed but are instead adaptive. Our framework can be extended to an active learning setting where the informativeness of an incoming instance across all the tasks can be evaluated using this adaptive interaction matrix. Empirical results on standardized datasets show improved performance in terms of accuracy, label complexity and number of mistakes made.
Importance of specialized cognitive function in the selection of military pilots.

Abstract : Visuospatial skills significantly distinguished student Naval aviators who dropped out of aviation training from those who received their wings. While both groups were better than average on these tests, the winged aviators were better than the dropout group by 0.25 standard deviation which is highly significant (P0.0001) for the total sample of 600 subjects. Performance on verbal-sequential skills did not distinguish between the groups. Logistic regression not only confirmed the group difference but demonstrated an interaction with verbal-sequential skills. High performance on these skills helped the odds of being winged for aviators with low visuospatial ability but hindered those with high visuospatial ability. Distribution of visusopatial scores for the 2 groups demonstrated reasonable cut-off points at which considerably more drop-outs than winged aviators could have been eliminated. However, these data are relevant only for the selected sample of aviators accepted for the training programs. An additional study on the entire group of applicants including those rejected would allow comparison between the special cognitive tests used in this study and those already used as selection criteria. Keywords: Cognitive Asymmetry; Cognitive Performance; Cognitive Processes, Cognitive Style; Hemispheric Specialization; Laterality; Pilot Selection.
Design and Analysis of a High-Efficiency High-Voltage Class-D Power Output Stage

The analysis and design of a highly-efficient 80 V class-D power stage design in a 0.14 μm SOI-based BCD process is described. It features immunity to the on-chip supply bounce, realized by internally regulated floating supplies, variable driving strength for the gate driver, and an efficient 2-step level shifter design. Fast switching transition and low switching loss are achieved with 94% peak efficiency for the complete class-D power stage in the realized chip.