Miracle-dz/UniFAR-FTUs huggingface dataset:
Training and development in small professional services firms

Purpose This paper aims to examine whether participation in training and development (T&D) events is associated with employees’ affective commitment and propensity to enact innovative behaviours in small professional services firms. The study also investigates associations between both attitudes towards T&D and policy and practice supportive of T&D and levels of participation in T&D events. Design/methodology/approach Data from 203 employees in small professional services firms employing 50 or fewer staff were analysed using regression analysis and PROCESS macro. Findings Only policy and practice supportive of T&D was associated with participation levels. Participation in T&D events was positively related to affective commitment. Furthermore, employees who participated in more T&D events were more likely to enact innovative behaviours, while affective commitment mediated the positive relationship between number of T&D events attended and innovative behaviours. Contrary to expectations, neither participation in just training nor participation in just development was associated with either attitudes or behaviours. Practical implications The findings have important implications for small firms which tend to rely on wholly work-based experiences for the development of employees’ knowledge and skills. Such an approach to learning for work may inadvertently shape a workforce that lacks commitment to the organisation and that has a diminished capacity for innovative behaviours. Originality/value There is limited research on how T&D affects attitudes and behaviours in small firms. Large and small firms are fundamentally different, thus findings from studies in large firms may not extend to small firms.
Lattice Boltzmann simulations of liquid-gas and binary fluid systems.

We present the details of a lattice Boltzmann approach to phase separation in nonideal one- and two-component fluids. The collision rules are chosen such that the equilibrium state corresponds to an input free energy and the bulk flow is governed by the continuity, Navier-Stokes, and, for the binary fluid, a convection-diffusion equation. Numerical results are compared to simple analytic predictions to confirm that the equilibrium state is indeed thermodynamically consistent and that the kinetics of the approach to equilibrium lie within the expected universality classes. The approach is compared to other lattice Boltzmann simulations of nonideal systems. \textcopyright{} 1996 The American Physical Society.
Development of Oral Morphine Rapid Test by Using Yolk Immunoglobulin

Avian antibody technology has been used in diagnosis and therapy. A”lab-on-a-chip” system for detecting morphine in an oral fluid sample was described. An antibody against morphine was obtained in an avian system. The immunogen (M-C6-HS-BSA) was injected into Leghorn chicken. Furthermore, this antibody could be used in developing an enzyme immunoassay and immunochromatography to detect morphine in a specific and sensitive manner. The reported rapid test was an optical immunoassay test for detection of morphine. Out of 50 specimens
'Pink eye' or 'zere oogjes' or keratoconjunctivitis infectiosa ovis (KIO). Clinical efficacy of a number of antimicrobial therapies.

In a comparative study the clinical efficacy of five different treatments of keratoconjunctivitis infectiosa ovis (KIO) were tested, namely an intramuscular injection of chloramphenicol base (dosage 15 mg/kg), spiramycin base (Suanovil dosages 10 to 25 mg/kg), oxytetracycline (Engemycine Forte, Terramycin LA, dosages respectively 5 and 10 mg/kg), tiamulin (Dynamutulin, dosage 10 mg/kg) and subcutaneous injection of procaine penicillin G, benzathine penicillin G. and dihydrostreptomycin in the lower eyelid. It appeared from these field trials that spiramycin base, oxytetracycline and tiamulin had a clearly positive effect on the clinical course of 'pink eye', although with tiamulin there was only a temporary effect (high percentage of relapses). In view of the field data the following dosage schemes are, for the time being, advised: spiramycin base (Suanovil), and oxytetracycline (formulation with a good biological availability) both 20 to 30 mg/kg and, if necessary, to be repeated on days 5 and 10 after the first intramuscular injection. The dosage scheme advised for tiamulin is 20-30 mg/kg to be repeated on day 3 and if necessary on days 6 and 9 after the intramuscular injection. In mild cases it is sufficient to rub the eyes with for example oxytetracycline eye-ointment, a few times a day.
Transglutaminase 2 Kinase Activity Facilitates Protein Kinase A-induced Phosphorylation of Retinoblastoma Protein*

Transglutaminase 2 (TG2, tissue transglutaminase) is a multifunctional protein involved in cross-linking a variety of proteins, including retinoblastoma protein (Rb). Here we show that Rb is also a substrate for the recently identified serine/threonine kinase activity of TG2 and that TG2 phosphorylates Rb at the critically important Ser780 residue. Furthermore, phosphorylation of Rb by TG2 destabilizes the Rb·E2F1 complex. TG2 phosphorylation of Rb was abrogated by high Ca2+ concentrations, whereas TG2 transamidating activity was inhibited by ATP. TG2 was itself phosphorylated by protein kinase A (PKA). Phosphorylation of TG2 by PKA attenuated its transamidating activity and enhanced its kinase activity. Activation of PKA in mouse embryonic fibroblasts (MEF) with dibutyryl-cAMP enhanced phosphorylation of both TG2 and Rb by a process that was inhibited by the PKA inhibitor H89. Treatment with dibutyryl-cAMP enhanced Rb phosphorylation in MEFtg2+/+ cells but not in MEFtg2–/– cells. These data indicate that Rb is a substrate for TG2 kinase activity and suggest that phosphorylation of Rb, which results from activation of PKA in fibroblasts, is indirect and requires TG2 kinase activity.
Exploring the Effective of Unexpectedness: An Extension of Expectation-Disconfirmation Theory

In highly competitive market of Apps, it's important to understand what drives customers to purchase Apps. We adopted EDT and introduced a new concept, which is named unexpectedness, to explore the phenomenon of App purchasing or continue using behavior. In our study, we separated Apps into two styles: utilitarian and hedonic, and argued that disconfirmation and unexpectedness have different effects on satisfaction of these two different style Apps.
A Multiobjective Particle Swarm Optimization-Based Partial Classification for Accident Severity Analysis

Reducing accident severity is an effective way to improve road safety. In this article, a novel multiobjective particle swarm optimization (MOPSO)-based partial classification method is employed to identify the contributing factors that impact accident severity. The accident dataset contains only a few fatal accidents but the patterns of fatal accidents are of great interest to traffic agencies. Partial classification can deal with the unbalanced dataset by producing rules for each class. The rules can be evaluated by several conflicting criteria such as accuracy and comprehensibility. A MOPSO is applied to discover a set of Pareto optimal rules. The accident data of Beijing between 2008 and 2010 are used to build the model. The proposed approach is compared with several rule-learning algorithms. The results show that the proposed approach can generate a set of accurate and comprehensible rules, which can indicate the relationship between risk factors and accident severity.
Benchmarks for effective primary care-based nursing services for adults with depression: a Delphi study.

AIM This paper is a report of a study conducted to identify and gain consensus on appropriate benchmarks for effective primary care-based nursing services for adults with depression. BACKGROUND Worldwide evidence suggests that between 5% and 16% of the population have a diagnosis of depression. Most of their care and treatment takes place in primary care. In recent years, primary care nurses, including community mental health nurses, have become more involved in the identification and management of patients with depression; however, there are no appropriate benchmarks to guide, develop and support their practice. METHOD In 2006, a three-round electronic Delphi survey was completed by a United Kingdom multi-professional expert panel (n = 67). FINDINGS Round 1 generated 1216 statements relating to structures (such as training and protocols), processes (such as access and screening) and outcomes (such as patient satisfaction and treatments). Content analysis was used to collapse statements into 140 benchmarks. Seventy-three benchmarks achieved consensus during subsequent rounds. Of these, 45 (61%) were related to structures, 18 (25%) to processes and 10 (14%) to outcomes. CONCLUSION Multi-professional primary care staff have similar views about the appropriate benchmarks for care of adults with depression. These benchmarks could serve as a foundation for depression improvement initiatives in primary care and ongoing research into depression management by nurses.
Haar wavelet decomposition of EEG signal for ocular artifact de-noising: a mathematical analysis

The de-noising of ocular artifacts from the electroencephalogram (EEG) signals based on existing filtering techniques results in a substantial loss of data. In our recent research, we have proposed the use of Haar wavelets for selective detection of the ocular artifacts and a control subsystem for their subsequent removal. Further, the application of this procedure to Alzheimer's EEG lead to the development of an efficient system for the early detection of the disease in clinical EEG recording itself. A detailed analysis of the Haar wavelet basis function and the EEG signal during the moments when the eye blinks occur produces interesting explanations for the success of this novel technique. This paper analyzes the process from a mathematical perspective and proposes a theory based on the properties of the Dirac-delta function and its relation to the ocular artifacts in normal and Alzheimer's EEG. The pre-seizure spike discharges occurring due to epilepsy also provide valuable information that is appropriate for testing the analysis and hence, are also examined.
State of the Art in Skinning Techniques for Articulated Deformable Characters

Skinning is an indispensable component of the content creation pipeline for character animation in the context of feature films, video games, and in the special effects industry. Skinning techniques define the deformation of the character skin for every animation frame according to the current state of skeletal joints. In this state of the art report, we focus on the existing research in the areas of skeleton-based deformation, volume preserving techniques and physically based skinning methods. We also summarize the recent research in deformable and soft bodies simulations for articulated characters, and discuss various geometric and examples-based approaches.
Inactivation of Piscine orthoreovirus.

Piscine orthoreovirus infects various salmonid fish species, and the infection is associated with diseases such as heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). There are no vaccines available or genetically selected resistant hosts that can efficiently control piscine orthoreovirus (PRV) infection. Currently, the only prophylactic measure against PRV is general biosecurity measures aiming to break the transmission cycle. Methods to eradicate infectious virus from contaminated facilities are desirable, but the knowledge on how to inactivate PRV is lacking. A major bottleneck for inactivation studies is the lack of ability to propagate PRV in cell culture. Therefore, in this study we developed an in vivo model for detection of infectious PRV particles after treatment of the virus with inactivation tools such as heat, pH, iodine, UV and commercially available disinfectants. The results show that standard iodine treatment is efficient in inactivation of the virus, and similarly are high and low pH extremes and treatment with Virocid, a commercially available disinfectant. A UV dose of at least 50 mJ/cm2 is required for inactivation, and the virus has high resistance against heat treatment.
Structure–function analysis of pneumococcal DprA protein reveals that dimerization is crucial for loading RecA recombinase onto DNA during transformation

Transformation promotes genome plasticity in bacteria via RecA-driven homologous recombination. In the Gram-positive human pathogen Streptococcus pneumoniae, the transformasome a multiprotein complex, internalizes, protects, and processes transforming DNA to generate chromosomal recombinants. Double-stranded DNA is internalized as single strands, onto which the transformation-dedicated DNA processing protein A (DprA) ensures the loading of RecA to form presynaptic filaments. We report that the structure of DprA consists of the association of a sterile alpha motif domain and a Rossmann fold and that DprA forms tail-to-tail dimers. The isolation of DprA self-interaction mutants revealed that dimerization is crucial for the formation of nucleocomplexes in vitro and for genetic transformation. Residues important for DprA–RecA interaction also were identified and mutated, establishing this interaction as equally important for transformation. Positioning of key interaction residues on the DprA structure revealed an overlap of DprA–DprA and DprA–RecA interaction surfaces. We propose a model in which RecA interaction promotes rearrangement or disruption of the DprA dimer, enabling the subsequent nucleation of RecA and its polymerization onto ssDNA.
Life Satisfaction of East European Migrants in Three Clustered European Destinations

This paper looks at the declared levels of happiness and life satisfaction of migrants from three East European countries: Bulgaria, Poland and Romania. The Inglehart–Welzel cultural map is used for grouping the main destination countries for East European (EE) migrants into three clusters: the Protestant cluster, the Englishspeaking cluster and the Catholic cluster. The well-being of East European migrants is compared between the three clusters and with that of natives using data from the first 7 waves of the European Social Survey. The article contains the following findings: both as a group and as distinct groups from the three countries of origin, EE migrants are most satisfied with life in the Protestant cluster and the least happy in the Catholic cluster; democratic structures are a key element for the life satisfaction of East European migrants.
Recruitment of a species-specific translational arrest module to monitor different cellular processes

Nascent chain-mediated translation arrest serves as a mechanism of gene regulation. A class of regulatory nascent polypeptides undergoes elongation arrest in manners controlled by the dynamic behavior of the growing chain; Escherichia coli SecM monitors the Sec protein export pathway and Bacillus subtilis MifM monitors the YidC membrane protein integration/folding pathway. We show that MifM and SecM interact with the ribosome in a species-specific manner to stall only the ribosome from the homologous species. Despite this specificity, MifM is not exclusively designed to monitor membrane protein integration because it can be converted into a secretion monitor by replacing the N-terminal transmembrane sequence with a secretion signal sequence. These results show that a regulatory nascent chain is composed of two modular elements, one devoted to elongation arrest and another devoted to subcellular targeting, and they imply that physical pulling force generated by the latter triggers release of the arrest executed by the former. The combinatorial nature may assure common occurrence of nascent chain-mediated regulation.
Competitive Analysis for the Flat-Rate Problem

SUMMARY We consider a problem of the choice of price plans o ﬀ ered by a telecommunications company: a “pay-as-you-go” plan and a “ﬂat-rate” plan. This problem is formulated as an online optimization problem extending the ski-rental problem, and analyzed using the competitive ratio. We give a lemma for easily calculating the competitive ratio. Based on the lemma, we derive a family of optimal strategies for a realistic class of instances. key words: online algorithm, competitive analysis, online optimization, ski-rental
Promoting Cancer Screening: Lessons Learned and Future Directions for Research and Practice

*This article is a US Government work and, as such, is in the public domain in the United States of America A large gap exists between the results of research concerning efficacious cancer screening programs and the programs delivered in practice. In this article, the authors discuss issues in, barriers to, and lessons learned regarding the dissemination of interventions. They summarize previous reviews, exemplary studies, and theories regarding the diffusion and dissemination of cancer screening interventions. Six lessons learned address the involvement of key stakeholders, factors influencing diffusion, the need for different types of efficacy and effectiveness studies with greater attention to external validity, replication, the use of theoretical and evaluation models, and the importance of policy infrastructure. In this article, the authors make recommendations for future research and practice, including improving the understanding of the intervention process and changing the types of grants funded and review criteria used. Also needed are an enhanced infrastructure, including policies to support dissemination, and the involvement of researchers, health care administrators, clinicians, and funding organizations in dissemination if the gap between research and practice in cancer screening is to be reduced. Cancer 2004;101(5 Suppl):1239 –50. Published 2004 by the American Cancer Society. *
The effect of tritiated thymidine on the developing oocytes of mice.

The effect of tritiated thymidine on the developing oocytes of mice was presented. Pregnant mice were injected a total of 7 times with 4 40 or 400 mcCi tritiated thymidine at 12-hour intervals between pregnancy Days 13 and 16. Animals were sacrificed on Day 17 or allowed to give birth. Radioactive label was detected by autoradiography. A high proportion of the oocyte nuclei on Day 17 of gestation and up to 1 month after birth contained tritium. The total number of oocytes in the ovaries was reduced in proportion to the isotope dose. The numbers of oocytes in the 40- and 4-mcCi groups were reduced to 1% and 50% of the control values respectively by 5 months of age. Mice born from mothers in the 400 mcCi group were lighter than those from controls (p less than .001). Fertility (no eggs or young) ovarian weight (p less than .001) and the capacity of the ovary to undergo compensatory hypertrophy after unilateral ovariectomy were affected in this group. It was concluded that mouse oocytes are highly sensitive to internal beta radiation from tritiated thymidine during embryonic development.
Synchrosqueezing transform: Application in the analysis of the K-complex pattern

K-complex is a pattern which appears in the sleep EEG and characterizes the second stage of the NREM sleep. According to the underlying role of studying this pattern, we propose using synchrosqueezing transform (SST) for The purpose of analysis and automatic detection of K-complex. SST is an EMD-like time-frequency algorithm for signal analysis. Our idea is based on the robust properties of the SST and its previous satisfactory results on biomedical signals, especially those with specific patterns. We successfully applied SST on 10 segments of 30 minutes sleep EEG signals which contain K-complexes labeled by two experts. Results illustrate that SST representation is able to detect this pattern at the right time and frequency locations in the time frequency plane, which are in consistency with the standard definition. Comparison with the continuous wavelet demonstrates the superiority of SST especially in finding K-complexes at the right places, reducing the blurredness and mistakenly detecting other part of the signal as K-complex.
A novel QoS-guaranteed proportional fairness with joint space-time-frequency scheduling

For the downlink of MIMO-OFDM system, a novel proportional fairness with joint space-time-frequency scheduling is proposed in this paper. On one hand, by space-time-frequency scheduling one can gain multiuser spatial multiplexing on the same subcarrier in one timeslot. On the other hand, with modified traditional proportional fairness, the system can provide QoS guarantee for various service types. The combination of space-time-frequency scheduling and novel proportional fairness makes the system perform well in respect of QoS provision without sacrificing much throughput.
Uncertain temporal reasoning for the distributed transportation scheduling problem

Distributed artificial intelligence (DAI) is suitable to applications where there is no central control. One of these applications with which we are concerned is transportation scheduling. We have noticed that all the approaches dedicated to this application use a weak representation of time and simple reasoning. Furthermore, these approaches ignore the uncertain behavior of agents. We propose an approach based on fuzzy temporal characteristic functions (FTCF) which allow a powerful representation of agent company behaviors, continually informing us about the degree of agent availability. Using this representation, we develop a temporal reasoning which allows inter and intra company cooperation to allocate trucks and to delegate orders.
Assessing risk and security in the housing market: A mixed-methods exploration of involuntary mobility

In this thesis, a conceptual definition of involuntary mobility is developed and used to estimate the incidence of such mobility between the years 2010 and 2012. This definition is then employed to understand how risk is structured in the housing market and how this impacts on the subjective sense of security derived from the home. The work of authors such as Beck (1992a; 1992b; 1994; 1999; 2010a; 2010b; 2011) and Giddens (1991), which considers risk as an inherent part of social structures, is drawn upon. This informs the adoption of the concept of precarity, which is utilised in order to understand the tenure arrangements in the private rented sector. Three empirical strands are drawn on. These are; the compilation of figures on individual reasons for residential mobility in order to build an incidence estimate for the years 2010–2012; the combination of two datasets, the British Household Panel Survey and Understanding Society, to assess the frequency of multiple involuntary moves; and the assessment through semi-structured interviewing of the impact that the ending by landlords of tenancies has on the subjective security tenants derive from their homes. It is found that involuntary mobility is widespread, and risk is seen to be an inherent part of the life course and embedded in the structures of the housing market. The concept of precarity, as it applies to the housing market, is reflected on. It is argued that precarity emerges at the intersection between legal and structural factors, here the tenancy agreement, the nature of private landlordism, and the structure of the private rented sector as a collection of small-scale landlords. Finally, it is found that the experience of such precariousness has a notable impact on the experience of private renting and the extent to which individuals feel ‘at home’ in the tenure.