Miracle-dz/UniFAR-FTUs huggingface dataset:
Clinical Investigation : Gynecologic Cancer Individualized Prediction of Overall Survival After Postoperative Radiation Therapy in Patients With Early-Stage Cervical Cancer : A Korean Radiation Oncology Group Study ( KROG 1303 )

Individualized Prediction of Overall Survival After Postoperative Radiation Therapy in Patients With Early-Stage Cervical Cancer: A Korean Radiation Oncology Group Study (KROG 13-03) Hyun Jin Lee, MD,* Seungbong Han, PhD,y Young Seok Kim, MD, PhD,* Joo-Hyun Nam, MD, PhD,z Hak Jae Kim, MD,x Jae Weon Kim, MD, PhD,jj Won Park, MD, PhD,{ Byoung-Gie Kim, MD, PhD, Jin Hee Kim, MD, PhD,** Soon Do Cha, MD, PhD,yy Juree Kim, MD, PhD,zz Ki-Heon Lee, MD, PhD,xx Mee Sun Yoon, MD, PhD,jjjj Seok Mo Kim, MD, PhD,{{ Ji-Yoon Kim, MD, Won Sup Yoon, MD, PhD,*** Nak Woo Lee, MD, PhD,yyy Jin Hwa Choi, MD,zzz Sang-Yoon Park, MD, PhD,xxx and Joo-Young Kim, MD, PhDxxx Departments of *Radiation Oncology, yClinical Epidemiology and Biostatistics, zObstetrics and Gynecology, Asan Medical Center, University of Ulsan, College of Medicine, Seoul; Departments of xRadiation Oncology and jjObstetrics and Gynecology, Seoul National University Hospital, Seoul; {Department of Radiation Oncology and Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul; **Department of Radiation Oncology and yyObstetrics and Gynecology, Dongsan Medical Center, Keimyung University School of Medicine, Daegu; Departments of zzRadiation Oncology and xxObstetrics and Gynecology, Cheil General Hospital and Women’s Healthcare Center, Kwandong University, College of Medicine, Seoul; jjjjDepartment of Radiation Oncology and {{Obstetrics and Gynecology, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Jeollanam-do; Department of Radiation Oncology, The Catholic University of Korea, College of Medicine, Seoul; Departments of ***Radiation Oncology and yyyObstetrics and Gynecology, Korea University Ansan Hospital, Ansan; zzzDepartment of Radiation Oncology, Chung-Ang University Hospital, Seoul; and xxxCenter for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Republic of Korea
Public Governance And Financial Development In Central And Eastern European Countries

Financial development has been accepted as an important component of economic growth together with the considerable improvements and expansions in financial sector during the recent years. Therefore, the determinants of financial development have gained importance. This study researches the interaction between public governance and the development of financial sector in 15 Central and Eastern European countries over the 2002-2015 period employing panel regression. The results of the paper revealed that most elements of the public governance are important factors for the development of financial sector.
A Power Law for Connectedness of Some Random Graphs at the Critical Point

We consider P(G is connected) when G is a graph with vertex set Z+ = {1,2, …}, and the edge between i and j is present with probability p(i, j) = min(λ h(i, j), 1) for certain functions h(i, j) homogeneous of degree -1. It is known that there is a critical value λc of λ such that . We show that the probability, at the critical point λc, that n1, and n2 are connected satisfies a power law, in the sense that for n2 ≧ nt ≧ 1 for any δ > 0 and certain constants c1 and c2.
Using Indirect protein-protein Interactions for protein Complex Prediction

Protein complexes are fundamental for understanding principles of cellular organizations. As the sizes of protein-protein interaction (PPI) networks are increasing, accurate and fast protein complex prediction from these PPI networks can serve as a guide for biological experiments to discover novel protein complexes. However, it is not easy to predict protein complexes from PPI networks, especially in situations where the PPI network is noisy and still incomplete. Here, we study the use of indirect interactions between level-2 neighbors (level-2 interactions) for protein complex prediction. We know from previous work that proteins which do not interact but share interaction partners (level-2 neighbors) often share biological functions. We have proposed a method in which all direct and indirect interactions are first weighted using topological weight (FS-Weight), which estimates the strength of functional association. Interactions with low weight are removed from the network, while level-2 interactions with high weight are introduced into the interaction network. Existing clustering algorithms can then be applied to this modified network. We have also proposed a novel algorithm that searches for cliques in the modified network, and merge cliques to form clusters using a "partial clique merging" method. Experiments show that (1) the use of indirect interactions and topological weight to augment protein-protein interactions can be used to improve the precision of clusters predicted by various existing clustering algorithms; and (2) our complex-finding algorithm performs very well on interaction networks modified in this way. Since no other information except the original PPI network is used, our approach would be very useful for protein complex prediction, especially for prediction of novel protein complexes.
Performance analysis of cyclic-priority input access method for a multicast switch

A study of the performance of a cyclic-priority input access mechanism for a multicast switch is carried out. The method is a derivative of the ring token reservation method which eliminates the unfairness of the ordinary ring token reservation. It has the further advantage of being simple and easy to implement. The primary performance measurements are the switch throughput and the packet delay. A key assumption is that all copies of the same packet must be switched in the same slot. <<ETX>>
Risk prediction model for respiratory complications after lung resection: An observational multicentre study

BACKGROUND Patients undergoing lung surgery are at risk of postoperative pulmonary complications (PPCs). Identifying those patients is important to optimise individual perioperative management. The Clinical Prediction Rule for Pulmonary Complications (CPRPCs) after thoracic surgery, developed by the Memorial Sloan-Kettering Cancer Center, might be an ideal predictor. The hypothesis was that CPRPC performs well for the prediction of PPCs. OBJECTIVE The aim of our study was to provide the external validation of the CPRPC after lung resection for primary tumours, before universal acceptance. In case of poor discrimination, we planned, as a second objective, to derive a new predictive index for PPCs. DESIGN Retrospective, observational multicentre study. PATIENTS A total of 559 adult consecutive patients who underwent pulmonary resection. Inclusion criteria were adult patients (aged over 17 years). SETTING Thirteen Spanish hospitals during the first half of 2011. INTERVENTIONS A record of the PPCs defined, as in the original publication, as the presence of any of the following events: atelectasis; pneumonia; pulmonary embolism; respiratory failure; and need for supplemental oxygen at hospital discharge. MAIN OUTCOME MEASURES The performance of the CPRPC was determined in order to examine its ability to discriminate and calibrate the presence of PPCs. RESULTS The study included 559 patients, of whom 75 (11.6%) suffered PPCs. The CPRPC did not show enough discriminatory power for our cohort area under the receiver operating characteristic (ROC) curve 0.47 (95% confidence interval 0.37 to 0.57)]. After a fitting step by stepwise multivariate logistic regression, we identified three main predictors of PPCs: age; smoking status; and predicted postoperative forced expiratory volume in 1 s. Combining them into a simple risk score, we were able to obtain an area under the ROC curve of 0.74 (95% confidence interval 0.68 to 0.79). CONCLUSION In this external validation, the CPRPC performed poorly despite its simplicity. The CPRPC was not a useful scale in our cohort. In contrast, we used a more accurate score to predict the occurrence of PPCs in our cohort. It is based on age, smoking status and predicted postoperative forced expiratory volume in 1 s. We propose that our formula should be externally validated.
An international comparison of long‐term average speech spectra

The long‐term average speech spectrum (LTASS) and some dynamic characteristics of speech were determined for 12 languages: English (several dialects), Swedish, Danish, German, French (Canadian), Japanese, Cantonese, Mandarin, Russian, Welsh, Singhalese, and Vietnamese. The LTASS only was also measured for Arabic. Speech samples (18) were recorded, using standardized equipment and procedures, in 15 localities for (usually) ten male and ten female talkers. All analyses were conducted at the National Acoustic Laboratories, Sydney. The LTASS was similar for all languages although there were many statistically significant differences. Such differences were small and not always consistent for male and female samples of the same language. For one‐third octave bands of speech, the maximum short‐term rms level was 10 dB above the maximum long‐term rms level, consistent across languages and frequency. A ‘‘universal’’ LTASS is suggested as being applicable, across languages, for many purposes including use in hearing aid prescription procedures and in the Articulation Index.
Cryo-Electron Tomography Elucidates the Molecular Architecture of Treponema pallidum, the Syphilis Spirochete

ABSTRACT Cryo-electron tomography (CET) was used to examine the native cellular organization of Treponema pallidum, the syphilis spirochete. T. pallidum cells appeared to form flat waves, did not contain an outer coat and, except for bulges over the basal bodies and widening in the vicinity of flagellar filaments, displayed a uniform periplasmic space. Although the outer membrane (OM) generally was smooth in contour, OM extrusions and blebs frequently were observed, highlighting the structure's fluidity and lack of attachment to underlying periplasmic constituents. Cytoplasmic filaments converged from their attachment points opposite the basal bodies to form arrays that ran roughly parallel to the flagellar filaments along the inner surface of the cytoplasmic membrane (CM). Motile treponemes stably attached to rabbit epithelial cells predominantly via their tips. CET revealed that T. pallidum cell ends have a complex morphology and assume at least four distinct morphotypes. Images of dividing treponemes and organisms shedding cell envelope-derived blebs provided evidence for the spirochete's complex membrane biology. In the regions without flagellar filaments, peptidoglycan (PG) was visualized as a thin layer that divided the periplasmic space into zones of higher and lower electron densities adjacent to the CM and OM, respectively. Flagellar filaments were observed overlying the PG layer, while image modeling placed the PG-basal body contact site in the vicinity of the stator-P-collar junction. Bioinformatics and homology modeling indicated that the MotB proteins of T. pallidum, Treponema denticola, and Borrelia burgdorferi have membrane topologies and PG binding sites highly similar to those of their well-characterized Escherichia coli and Helicobacter pylori orthologs. Collectively, our results help to clarify fundamental differences in cell envelope ultrastructure between spirochetes and gram-negative bacteria. They also confirm that PG stabilizes the flagellar motor and enable us to propose that in most spirochetes motility results from rotation of the flagellar filaments against the PG.
A Study on Neural Network Language Modeling

An exhaustive study on neural network language modeling (NNLM) is performed in this paper. Different architectures of basic neural network language models are described and examined. A number of different improvements over basic neural network language models, including importance sampling, word classes, caching and bidirectional recurrent neural network (BiRNN), are studied separately, and the advantages and disadvantages of every technique are evaluated. Then, the limits of neural network language modeling are explored from the aspects of model architecture and knowledge representation. Part of the statistical information from a word sequence will loss when it is processed word by word in a certain order, and the mechanism of training neural network by updating weight matrixes and vectors imposes severe restrictions on any significant enhancement of NNLM. For knowledge representation, the knowledge represented by neural network language models is the approximate probabilistic distribution of word sequences from a certain training data set rather than the knowledge of a language itself or the information conveyed by word sequences in a natural language. Finally, some directions for improving neural network language modeling further is discussed.
How to reduce turnover intention in team sports? Effect of organizational support on turnover intention of professional team sports athletes

Turnover of employees is a key challenge for companies. The same is true for sports clubs that must set appropriate incentives to decrease their athletes’ turnover intention. As salary caps and team budgets restrict monetary incentives, the purpose of this paper is to investigate the effect of organizational support on turnover intention of professional team sports athletes. ,The paper applies a combined approach of qualitative and quantitative research and considers the specific requirements of European professional team sports. First, a qualitative study investigates organizational support in team sports and identifies relevant non-monetary incentives. Second, a quantitative study tests the effects of the identified organizational support incentives on turnover intention using a unique data set of professional team sports athletes. Third, a moderation analysis measures possible effects of age. ,Through the qualitative study, three relevant non-monetary incentives could be identified in the context of professional team sports: integration of family (IOF), second career support, and private problem support. The subsequent quantitative study of football, ice hockey and handball athletes assesses the effectiveness of the identified incentives. All three incentives negatively influence athletes’ turnover intention, while IOF has a substantially stronger negative effect on turnover intention for younger athletes. ,The findings indicate the importance of organizational support to decrease athletes’ turnover intention. Although money is relevant, sports clubs also need to address non-monetary incentives to decrease their athletes’ turnover intention.
Design of a Regional Venture-Creation Ecosystem by Reusing Components of Another Ecosystem

Building a regional ecosystem to support the launch and growth of ventures is complex, time consuming, and risky. Instead of building the venture-creation ecosystem from scratch, individuals and organizations in a region may try to reuse components of an existing venture-creation ecosystem they deem to be successful in another region. This research identifies the defining features of business ecosystems, develops a framework to specify business ecosystems, and produces a design and a plan to build a regional venture-creation ecosystem in Jordan. The design adapts the goals and components of Lead To Win, a venture-creation ecosystem in Ottawa, Canada. This research is relevant to individuals and organizations building venture-creation regional ecosystems and seeking guidance on how to reuse components from ecosystems in other regions, and to researchers seeking to better understand the configuration required to attain similar goals in different regions. It also guides building a venture-creation ecosystem in Jordan.
Lactobacillus brevis responds to flavonoids through KaeR, a LysR‐type of transcriptional regulator

The ability of transcription factors to respond to flavonoids as signal molecules was investigated in Lactobacillus brevis. Through in vitro screening of a small library of flavonoids, LVIS1989 (KaeR), a LysR‐type transcriptional regulator (LTTR), was identified as responsive to kaempferol. The modulation of KaeR activity by flavonoids was characterized in vivo and in vitro. DNase I footprint assays identified the binding of KaeR at two distinctive sites, one in the intergenic region between LVIS1988 and kaeR (−39 to +2) and another within LVIS1988 (−314 to −353, from kaeR translational start point). EMSA assays revealed that both binding sites are required for KaeR binding in vitro. Furthermore, KaeR–DNA interactions were stabilized by the addition of kaempferol (20 µM). In vivo qRT‐PCR experiments performed in L. brevis confirmed that the divergently transcribed genes LVIS1988, LVIS1987 and LVIS1986 and kaeR are upregulated in the presence of kaempferol, indicating the role of KaeR as a transcriptional activator. Transcriptional lacZ fusions using Bacillus subtilis as a surrogate host showed that expression of kaeR and LVIS1988 were induced by the presence of the flavonoid. These results indicate that KaeR belongs to a small and poorly understood group of LTTRs that are positively autoregulated in the presence of a ligand.
Does Medical Diagnosis Data Clarify the Relation Between Prenatal Care and Delivery Outcomes

Studies indicating that prenatal care has minimal impact sparked additional work to assess whether this is a correct conclusion or a statistical artifact. Recent work highlights the importance of including medical diagnoses as regression variables, developing inclusive measures for health outcomes, and using providergenerated measures of prenatal care utilization. We explore these issues using administrative data provided by a tertiary care hospital and a prenatal care clinic. This data includes provider-generated utilization data, coded medical diagnoses, and variable direct costs for delivery-episode hospital care. Because all patients in this dataset obtained care from one set of providers in one urban area, the data set also minimizes heterogeneity due to variations in provider practice patterns and community services. We find that prenatal care exerts a significant beneficial impact on infant outcomes, and variable direct cost provides an inclusive outcomes measure when appropriate exogenous control variables are available. Estimated per-visit cost savings range from zero for patients with no diagnoses, to $10 for patients with one diagnosis, and $22 for patients with multiple diagnoses. The differences among these per-visit savings are significant, suggesting suboptimal allocation of clinic resources. Prenatal care utilization does not, however, increase with the number of diagnoses.
Leader-member exchange, safety climate and employees’ safety organizational citizenship behaviors in container terminal operators

Purpose Container terminal operation is one of the most risky industries. Many of the accidents that occurred were found to be caused by human errors. However, it seems relatively little research has been conducted to examine the influence of leader-member exchange (LMX) relationship on employee safety behavior. Therefore, the purpose of this study is to examine the effects of leader-member exchange and safety climate on employees’ safety organizational citizenship behaviors (SOCB) in the container terminal context based on the social exchange theory. Design/methodology/approach A structural equation modeling was used with confirmatory factor analysis, and survey data are collected from 265 employees in major container terminals in Taiwan. Findings Results indicated that LMX is positively associated with safety climate, whereas safety climate positively influences employees’ safety citizenship behavior. Specifically, results indicated that safety climate mediates the effect of LMX on employees’ SOCB. Research limitations/implications This study was limited to LMX dimensions adapted from the studies of Li and Liao (2014) and Vidyarthiv et al. (2014). Future research could examine the linkages between LMX, ethical climate, safety performance and supervisor leadership influence. Furthermore, this research focused specifically on employees from the container terminal operators in Taiwan. It would be valuable to collect data from employees from other countries to obtain a balanced view of the relationship between LMX, team-member exchange (TMX), safety climate and employee SOCB in container terminal operations. Practical implications This research provides a useful implication for container terminal operators to enhance LMX qualities and employee safety behavior through organizational participation, employee-helping behaviors and informing workers to obey safety rule and regulation. Originality/value Given the prevalence of accidents and unsafe behavior in container terminal operations, this research sought to examine the relationships among LMX, safety climate and employee SOCB in the container terminal context. Theoretically, this study highlights the importance of LMX and safety climate in explaining the SOCB of employees.
The FELS method of assessing the skeletal maturity of the hand‐wrist

The FELS method of assessing the skeletal maturity of the hand‐wrist differs from the Greulich‐Pyle and Tanner‐Whitehouse methods in the observations made, the provision of a range of shapes to which maturity indicator grades can be assigned and in the statistical methods used to construct the scale of skeletal maturity. The FELS method for the hand‐wrist was developed using 13,823 serial radiographs of the left hand‐wrist of boys and girls in the Fels Longitudinal Study. One hundred‐thirty possible indicators were originally identified. Eighty‐five graded and 13 metric indicators were selected on the basis of an indicator's ability to discriminate between children at the same chronological age, its universal appearance, reliability, validity, and completeness. The subset of FEELS maturity indicators assessed at a chronological age are analyzed with a microcomputer program that provides the skeletal age and the standard error of the estimate for that skeletal age. Comparison among hand‐wrist skeletal age assessments for children in the Fels Longitudinal Study by the FELS, Greulich‐Pyle, and Tanner‐Whitehouse methods indicate that the FELS method is the more appropriate method for the present population of United States children.
Career Anchors of Information Systems Personnel

Abstract:Career research in the information systems (IS) field has primarily focused on external motivators associated with organizational factors and material incentives. IS empirical research investigating the internalized career orientations of practitioners is necessary to match individual expectations with corporate human resource planning.This study identifies several career anchors or orientations maintained by IS personnel. By administering the Career Orientations Inventory to 321 IS personnel, Managerial and Technical Competence, Identity, Service, Organizational Stability, and Variety career orientations are distinguished. These internal anchors significantly influence how IS and human resource management should (1) plan corporate IS career paths, (2) nurture IS employees during their careers, and (3) encourage appropriate communication about career advancement.