Miracle-dz/UniFAR-FTUs huggingface dataset:
La nouvelle révolution commerciale

Bouleversements sociaux, economiques, ecologiques, viennent impacter les comportements d’achat des consommateurs et amenent le secteur de la distribution a revolutionner son fonctionnement. C’est l’emergence d’un nouveau modele economique que Philippe Moati, Professeur d’economie a l’Universite Paris Diderot, nous propose.
Trained Immunity and Susceptibility to HIV

ABSTRACT In this issue of Clinical and Vaccine Immunology, K. Jensen et al. (Clin Vaccine Immunol 24:e00360-16, 2017, https://doi.org/10.1128/CVI.00360-16 ) describe a dual-purpose attenuated Mycobacterium tuberculosis-simian immunodeficiency virus vaccine (AMTB-SIV). Interestingly, immunized infant macaques required fewer oral exposures to SIV to become infected relative to nonimmunized animals. The authors hypothesized that augmented susceptibility to SIV was due to activation of CD4+ T cells through trained immunity. This commentary explores the possible relationship between trained immunity, enhanced CD4 T cell responses, and increased susceptibility to human immunodeficiency virus (HIV).
A Novel Spatial-Multiplexing OFDM System with Transmit Diversity Based on SFBC

A novel spatial-multiplexing orthogonal frequency- division multiplexing (OFDM) transmission system with transmit diversity provided by space-frequency block code (SFBC) is proposed in this paper. The proposed scheme combines Alamouti scheme and Bell Labs layered space-time (BLAST) together, thus can achieve transmit diversity and spatial multiplexing gains altogether. Two-step iterative detection algorithm is also proposed for this system, in which MMSE detection is performed firstly and then SFBC decoding coupled with successive interference cancellation (SIC) is performed separately and iteratively for each layer. Simulation results show that the proposed system with iterative detection algorithm can achieve better tradeoff between transmission rate and bit error rate (BER) performance than existing multiple-input multiple-output (MIMO) OFDM systems.
Trades of the Living Dead: Style Differences, Style Persistence and Performance of Currency Fund Managers

We make use of a new database on daily currency fund manager returns over a three-year period, 2005-08. This higher frequency data allows us to estimate both alpha measures of performance and beta style factors on a yearly basis, which in turn allows us to test for persistence. We find no evidence to support alpha persistence; a manager's alpha in one year is not significantly related to his alpha in the prior year. On the other hand, there is substantial evidence for style persistence; funds that rely on carry, trend or value trading or with a long/short bias toward currency volatility are likely to maintain that style in the following year. In addition, we are able to examine the performance of managers that survive through the entire sample period, versus those that drop out. We find significant differences in both the investment styles of living versus deceased funds, as well as their realized alpha performance measures. We conjecture that both style differences and ineffective market timing, rather than market conditions, have impacted performance outcomes and induced some managers to close their funds.
Identification of Staphylococcus spp. by PCR-Restriction Fragment Length Polymorphism of gapGene

ABSTRACT Oligonucleotide primers specific for the Staphylococcus aureus gap gene were previously designed to identify 12Staphylococcus spp. by PCR. In the present study,AluI digestion of PCR-generated products rendered distinctive restriction fragment length polymorphism patterns that allowed 24 Staphylococcus spp. to be identified with high specificity.
Using Conditional Random Fields with Constraints to Train Support Vector Machines - Locating and Parsing Bibliographic References

This paper shows how bibliographic references can be located in HTML and then be separated into fields. First it is demonstrated, how Conditional Random Fields (CRFs) with constraints and prior knowledge about the bibliographic domain can be used to split bibliographic references into fields e.g. authors and title, when only a few labeled training instances are available. For this purpose an algorithm for automatic keyword extraction and a unique set of features and constraints is introduced. Features and the output of this Conditional Random Field (CRF) for tagging bibliographic references, Part Of Speech (POS) analysis and Named Entity Recognition (NER) are then used to find the bibliographic reference section in an article. First, a separation of the HTML document into blocks of consecutive inline elements is done. Then we compare one machine learning approach using a Support Vector Machines (SVM) with another one using a CRF for the reference locating process. In contrast to other reference locating approches, our method can even cope with single reference entries in a document or with multiple reference sections. We show that our reference location process achieves very good results, while the reference tagging approach is able to compete with other stateof-the-art approaches and sometimes even outperforms them.
Targeting of herbal bioactives through folate receptors: a novel concept to enhance intracellular drug delivery in cancer therapy

Abstract Targeted drug delivery through folate receptor (FR) has emerged as a most biocompatible, target oriented, and non-immunogenic cargoes for the delivery of anticancer drugs. FRs are highly overexpressed in many tumor cells (like ovarian, lung, breast, kidney, brain, endometrial, and colon cancer), and targeting them through conjugates bearing specific ligand with encapsulated nanodrug moiety is undoubtedly, a promising approach toward tumor targeting. Folate, being an endogenous ligand, can be exploited well to affect various cellular events occurring during the progress of tumor, in a more natural and definite way. Thus, the aim of the review lies in summarizing the advancements taken place in the drug delivery system of different therapeutics through FRs and to refine its role as an endogenous ligand, in targeting of synthetic as well as natural bioactives. The review also provides an update on the patents received on the folate-based drug delivery system.
Qaā būs ibn Wushmagīr: A study of rhythm patterns in Arabic epistolary prose from the 4th century ah (10th century ad )

This study focuses on the Arabic prose style of Qābūs ibn Wushmagīr, a Persian ruler of the 4th century AH (10th century AD ). Through a textual analysis of a selection of his letters it identifies some fascinating rhythmical patterns using the statistical technique of log-linear modelling. The quantitative analyses are based specifically on syllable patterns in the texts which are evaluated according to the theme of each letter. The study concludes that in some letter types in particular there is a certain predictability in the rhythmical patterns of the text which indicate that the style of a given piece was determined to some degree by the theme of the letter.
Immune regulation by 4‐1BB and 4‐1BBL: complexities and challenges

Summary: The tumor necrosis factor receptor family member 4‐1BB plays a key role in the survival of activated and memory CD8+ T cells. Depending on the disease model, 4‐1BB can participate at different stages and influence different aspects of the immune response, likely due to the differential expression of receptor and ligand relative to other costimulatory molecules. Studies comparing mild versus severe influenza infection of mice suggest that the immune system uses inducible receptors such as 4‐1BB to prolong the immune response when pathogens take longer to clear. The expression of 4‐1BB on diverse cell types, evidence for bidirectional as well as receptor‐independent signaling by 4‐1BBL, the unexpected hyperproliferation of 4‐1BB‐deficient T cells, and complex effects of agonistic anti‐4‐1BB therapy have revealed additional roles for the 4‐1BB/4‐1BBL receptor/ligand pair in the immune system. In this review, we discuss these diverse roles of 4‐1BB and its ligand in the immune response, exploring possible mechanisms for the observed complexities and implications for therapeutic applications of 4‐1BB/4‐1BBL.
Profissão perigo: percepção de risco à saúde entre os catadores do Lixão do Jangurussu

Este estudo descreve as dificuldades de trabalho vivenciadas por um grupo de catadores de lixo aproveitavel num lixao situado na malha urbana de Fortaleza, segundo a optica desses sujeitos. Correlaciona o ambiente de catacao com os fatores de risco e danos a saude relacionados a esse tipo de ocupacao.Fundamentados na observacao livre da atividade e em entrevistas nao-estruturadas, os resultados evidenciaram uma atividade perigosa e insalubre, embora, muitas vezes, se constitua a unica forma de sobrevivencia para um grande numero de pessoas. Os dados revelaram ainda que os catadores utilizam estrategias defensivas para minimizar e acobertar os riscos presentes no ambiente da catacao de lixo, para poderem dar continuidade a sua rotina de trabalho. Palavras-chave: catadores de lixo, percepcao de risco, ambiente ocupacional, condicoes de trabalho, saude coletiva.
Appendix for ” Does Home Production Drive Structural Transformation ? ”

∗Contact: Deparment of Economics and Business, University of Cagliari, Via Sant’Ignazio 17, 09123, Cagliari, Italy. Tel: +39 070 675 3341. E-mail: amoro@unica.it †Contact: Department of Economics, Monash University, Building H, 900 Dandenong Road, Caulfield East, VIC 3145, Australia. Tel: +61 3 990 34518. E-mail: solmaz.moslehi@monash.edu. au ‡Contact: School of Economics, University of Queensland, Level 6 Colin Clark Building, Blair Dr, QLD 4072, Australia. Tel: +61 7 334 67051. E-mail: s.tanaka@uq.edu. au
Optimizing the bandwidth utilization in distributed storage systems. (Optimiser l'utilisation de la bande passante dans les systèmes de stockage distribué)

Modern storage systems have to face the surge of the amount of data to handle. At the current scale, it would be an illusion to believe that a single centralized storage device is able to store and retrieve all its users' data. While from the user's viewpoint the storage system remains a single interlocutor, its underlying architecture has become necessarily distributed. In others words, storage is no longer assigned to a centralized storage equipment, but is now distributed between multiple independent storage devices, connected via a network. Therefore, when designing networked storage systems, bandwidth should now be taken into account as a critical resource. In fact, the bandwidth of a system is intrinsically a limited resource which should be handled with care to avoid congestion. The focus of this thesis is to optimize the available bandwidth of distributed storage systems, lowering the impact of churn and failures. The objective is twofold, on the one hand the purpose is to increase the available bandwidth for data exchanges and on the other hand, to decrease the amount of bandwidth consumed by maintenance. We present three distinct contributions in this manuscript. The first contribution of this thesis presents an hybrid peer-to-peer architecture taking into account the low level topology of the network i.e., the presence of gateways between the system and the users. The second contribution proposes an adaptive and user-level timeout mechanism, based on a Bayesian approach. The third contribution describes a repair protocol especially designed for erasure-coded stored data. Finally, this thesis concludes on the possibility of employing interference alignment techniques in order to increase the efficiency of repair protocols especially designed for encoded data.
Throughput and Power Efficiency Evaluation of Block Ciphers on Kepler and GCN GPUs Using Micro-Benchmark Analysis

Computer systems with GPUs are expected to become a strong methodology for high-speed encryption processing. Moreover, power consumption has remained a primary deterrent for such processing on devices of all sizes. However, GPU vendors are currently announcing their future roadmaps of GPU architecture development: Nvidia Corp. promotes the Kepler architecture and AMD Corp. emphasizes the GCN architecture. Therefore, we evaluated throughput and power efficiency of three 128-bit block ciphers on GPUs with recent Nvidia Kepler and AMD GCN architectures. From our experiments, whereas the throughput and per-watt throughput of AES-128 on Radeon HD 7970 (2048 cores) with GCN architecture are 205.0 Gbps and 1.3 Gbps/Watt respectively, those on Geforce GTX 680 (1536 cores) with Kepler architecture are, respectively, 63.9 Gbps and 0.43 Gbps/W; an approximately 3.2 times throughput difference occurs between AES-128 on the two GPUs. Next, we investigate the reasons for the throughput difference using our micro-benchmark suites. According to the results, we speculate that to ameliorate Kepler GPUs as co-processor of block ciphers, the arithmetic and logical instructions must be improved in terms of software and hardware. key words: throughput, power efficiency, GPU, OpenCL, AES, Camellia, SC2000, Kepler, Graphics Core Next
Single-trial P300 Classification using PCA with LDA, QDA and Neural Networks

The P300 event-related potential (ERP), evoked in scalp-recorded electroencephalography (EEG) by external stimuli, has proven to be a reliable response for controlling a BCI. The P300 component of an event related potential is thus widely used in brain-computer interfaces to translate the subjects' intent by mere thoughts into commands to control artificial devices. The main challenge in the classification of P300 trials in electroencephalographic (EEG) data is the low signal-to-noise ratio (SNR) of the P300 response. To overcome the low SNR of individual trials, it is common practice to average together many consecutive trials, which effectively diminishes the random noise. Unfortunately, when more repeated trials are required for applications such as the P300 speller, the communication rate is greatly reduced. This has resulted in a need for better methods to improve single-trial classification accuracy of P300 response. In this work, we use Principal Component Analysis (PCA) as a preprocessing method and use Linear Discriminant Analysis (LDA)and neural networks for classification. The results show that a combination of PCA with these methods provided as high as 13\% accuracy gain for single-trial classification while using only 3 to 4 principal components.
Flujos estomáticos de ozono y sus efectos sobre la vegetación relaciones dosis-respuesta

En este trabajo se establecen relaciones de dosis-respuesta para cultivos de lechuga. Con este objetivo se ha desarrollado un modelo multiplicativo de conductancia estomatica (gs), segun el cual se puede describir la influencia que determinados parametros ambientales ejercen sobre gs. El modelo fue calibrado utilizando una base de datos de medidas de gs tomadas en campo durante un experimento desarrollado en Creta (Grecia). De forma paralela se realizo un experimento de fumigacion con ozono en camaras descubiertas para determinar el efecto del ozono sobre la produccion de la lechuga. Ambos experimentos se realizaron respetando las practicas agronomicas normales para este cultivo. El analisis de valores de gs modelizados frente a medidos mostro que el modelo multiplicativo explico un 51% (P < 0,001) de la variabilidad observada en las medidas. Tambien se realizo una comparacion entre indices basados en la concentracion de ozono e indices basados en el flujo absorbido. Se encontraron regresiones significativas entre la dosis de ozono absorbida y la produccion cuando se emplearon umbrales inferiores a los 4 nmol m-2 s-1. Estos analisis mostraron que las relaciones dosis-respuesta mas importantes se dieron cuando la dosis se acumulaba por encima de valores umbrales muy bajos o nulos. En estos casos, las relaciones dosis-respuesta explicaron hasta un 80% (P < 0,05) de la variabilidad encontrada en la respuesta de la lechuga frente al ozono en terminos de produccion.
Clinical outcomes for maintenance hemodialysis patients using a high-flux (FX60) dialyzer

Abstract Aims: To investigate the clinical outcomes of maintenance hemodialysis (HD) patients using a high-flux (FX60) dialyzer. Method: Thirty patients undergoing dialysis for at least 2 years with a low-flux dialyzer were switched to the FX60 dialyzer for 3 years. Clinical and biochemical analysis was performed monthly for each patient. The parameters monitored included blood pressure, hemoglobin, albumin, intact parathyroid hormone (iPTH), calcium and phosphorus levels, the adequacy of dialysis (Kt/V), beta2-microglobulin (β2-MG) clearance rate, as well as antihypertensive and erythropoietin (EPO) medications. Results: After 3 years of dialysis with an FX60 dialyzer, the mean arterial blood pressure fell, hemoglobin increased, serum phosphate level decreased, iPTH declined and medication doses decreased. Conclusions: Dialysis with the FX60 dialyzer has a better clinical outcome for rectifying renal anemia, controlling hypertension and lowering serum phosphate levels making it a better choice for long-term HD patients.
Choice of magnetic induction and current density values for planar magnetic design

This paper presents a methodology for determining the values of magnetic induction and current density for the design of transformers and inductors using planar magnetic elements. From experimental values as well as datasheet parameters and by using an optimization tool based on genetic algorithms, we obtained curves of magnetic induction and current density corresponding to operation with minimal magnetic losses. From the obtained results, it is possible to design a planar magnetic device operating with minimal losses.
Xenopus borealis and Xenopus laevis 28S ribosomal DNA and the complete 40S ribosomal precursor RNA coding units of both species

We have determ ined the nucleotide sequence of Xenopus borealis 28 ribosomal DNA (rDNA) and have revised the sequence of Xenopus laevis 285 rDNA (Ware et al., Nucl. Acids Res. 11, 7795—7817 (1983)). In the regions encoding the conserved structural core of 285 rRNA (2490 nucleotides) there are only four differences between the two species, each difference being a base substitution. In the variable regions, also called eukaryotic expansion segments (ca. 1630 nucleotides) there are some 61 differences, due to substitutions, mini-insertions and mini-deletions. Thus, evolutionary divergence in the variable regions has been at least 20-fold more rapid than in the conserved core. A search for intraspecies sequence variation has revealed minimal heterogeneity in X. laevis and none in X. borealis. At three out of four sites where heterogeneity was found in X. laevis (all in variable regions) the minority variant corresponded to the standard form in X. borealis. Intraspecies heterogeneity and interspecies divergence in the 28S variable regions are much less extensive than in the transcribed spacers. The 28S sequences are Irom the same clones that were used previously for sequencing the 18S genes and transcribed spacers. The complete sequences of the 405 precursor regions of the two reference clones are given.
A Variable Neighbourhood Search Algorithm with Compound Neighbourhoods for VRPTW

The Vehicle Routing Problem with Time Windows (VRPTW) consists of constructing least cost routes from a depot to a set of geographically scattered service points and back to the depot, satisfying service time interval and capacity constraints. A Variable Neighbourhood Search algorithm with Compound Neighbourhoods is proposed to solve VRPTW in this paper. A number of independent neighbourhood operators are composed into compound neighbourhood operators in a new way, to explore wider search area concerning two objectives (to minimize the number of vehicles and the total travel distance) simultaneously. Promising results are obtained on benchmark datasets
Endorectal fusion imaging: A description of a new technique

Background: Fusion imaging is an accepted method in abdominal imaging allowing a simultaneous display of reference imaging with a live ultrasound (US) investigation. For prostate cancer, promising results have been published for endorectal US (ERUS)-guided biopsy of suspicious lesions in magnetic resonance imaging (MRI). To our knowledge, no other indication for the fusion of ERUS with MRI has been reported so far. Methods: We report on three patients scheduled for ERUS due to anorectal fistulae after treatment (n = 2) or rectal carcinoma (n = 1), which were scheduled for real-time virtual onography (RVS), a method for the fusion of MRI imaging with US. Results: In all patients, RVS was successful. The course of the fistulae could be defined and the success of the treatment could be confirmed. In the patient with rectal carcinoma, the lymph nodes suspicious in MRI could be identified. Conclusions: MRI/ERUS fusion has the potential for follow-up of anorectal fistulae and abscesses, and staging of anal and rectal tumors.
Dental caries in 0- to 5-year-old Brazilian children: prevalence, severity, and associated factors.

OBJECTIVE This cross-sectional study investigated the prevalence and severity of dental caries and their association with demographic and socio-economic variables in Brazilian preschoolers. METHODS The study population comprised 1487 0- to 5-year-old children attending government nurseries in Canoas, southern Brazil. Questionnaires regarding information related to the independent variables (age, gender, maternal level of education, and family income) were completed by the parents. Clinical examinations were carried out by five trained examiners and results were expressed using the deft index (World Health Organization criteria), including white spots. The outcomes considered in this study were caries occurrence (deft > 0) and caries severity (deft). RESULTS Forty per cent of the children (589/1487) presented dental caries [mean deft (SD): 1.53 (2.75)]. Deft increased with age (P < 0.001) and was significantly higher in children from mothers with low educational level (P = 0.001) and low family income (P = 0.001). The greatest increase in caries prevalence and severity occurred between age groups of 1 and 2 years. Logistic regression demonstrated higher odds of dental caries with mother's completing < 4 years education, after adjusting for confounding. CONCLUSION These findings indicate the need for preventive programmes, which should begin in the first year of life, with special attention given to families with mothers presenting low education levels.
SOME CHARACTERIZATIONS OF REAL HYPERSURFACES OF TYPE (A) IN A NONFLAT COMPLEX SPACE FORM

In this paper, we prove that if the structure Jacobi operator Rξ is ξ-parallel and Rξ commutes with the Ricci tensor S, then a real hypersurface with non-negative scalar curvature of a nonflat complex space form Mn(c) is a Hopf hypersurface. Further, we characterize such Hopf hypersurface in Mn(c).
Solubility, Stability and Ionization Behaviour of Famotidine

Abstract— The pKa of famotidine was determined at 23±0·2°C to be 6·76, 6·98 and 6·89 by a spectrophotometric, solubility, and partitioning method, respectively. The pH‐solubility profile of famotidine indicated an intrinsic solubility of 2·7 Mm at 23°C. Degradation of famotidine followed pseudo‐first‐order kinetics over a pH range of 1–11 at 37±0·2°C and at an ionic strength (μ) of 0·5. The pH‐rate profile was accounted for by the specific acid and base catalysed reactions as well as water‐catalysed decomposition of both protonated and free famotidine. A pKa of 6·60, determined by potentiometry at 37±0·5°C (μ = 0·5), was used in the kinetic calculations. Maximum stability occurred at pH 6·3. Undissociated acetic acid, dihydrogen phosphate ion and glycine anion were found to contribute to the general acid and base catalyses. pH‐dependency of the apparent octanol‐water partition coefficient of famotidine indicated a partition coefficient of 0·23 for free famotidine at 23±0·2°C.