Miracle-dz/UniFAR-FTUs huggingface dataset:
Doing the plastic fantastic: ‘artificial’ adventure and older adult climbers

ABSTRACT The aim of this article is to determine the perceptions and experiences of climbing at artificial climbing walls (ACWs) as undertaken by a cohort of ‘young-old’ people (approximately 65–75 years). The engagement of older people in outdoor activities and adventure is an evolving topic; however, as part of this development, little has been written on the use of ACWs. Methodologically, the research employed in-depth semi-structured focus groups and interviews with a purposive convenience sample of six recreational climbers, subsequently expanded to ten through snowball technique. Both sexes were equally represented. Manual thematic analysis identified two key motifs: ACWs and the notion of adventure, and ACWs and the potential for learning. The findings point at what constitutes ‘real’ adventure for this group of older adults; the shifting nature of ‘old age’; the significance of self-awareness; and the role of reflexivity and physical activity in the construction of a ‘successful’ old age.
Regulation of biliary cholesterol output in the rat: dissociation from the rate of hepatic cholesterol synthesis, the size of the hepatic cholesteryl ester pool, and the hepatic uptake of chylomicron cholesterol.

These studies were designed to determine the importance of the rate of hepatic cholesterol synthesis, the size of the hepatic cholesteryl ester pool, the amount of chylomicron cholesterol reaching the liver, and the rate of bile acid transport into bile as determinants of the rate of biliary cholesterol output. Female rats that had been subjected to diurnal light cycling, fasting for 48 hr, intravenous administration of chylomicrons, and diets containing either cholestyramine, cholesterol, or bile acid underwent total biliary diversion for 2 hr. The animals were then killed and the rates of hepatic cholesterol synthesis and levels of hepatic esterified cholesterol were measured along with biliary lipid concentrations. Despite a 1000-fold variation in the rate of hepatic cholesterogenesis and a 100-fold variation in the levels of cholesteryl esters, the output and molar percentage of cholesterol in bile remained essentially constant with the exception of an approximate doubling in the output of cholesterol, as well as of bile acid and phospholipid in those animals fed bile acid. However, in this latter group the molar percentage of each component was unchanged. The administration of a bolus of chylomicrons did not alter output or molar percentage of cholesterol. Total biliary diversion for 36 hr and bile acid infusion were used to markedly vary the rate of biliary bile acid output. Cholesterol and phospholipid output remained tightly coupled to bile acid output over almost a 40-fold range. In other experiments it was shown that biliary cholesterol output could be driven by bile acid infusion to a similar extent in rats in which the rate of hepatic cholesterogenesis had been varied over a 26-fold range. It was concluded that the rate of hepatic cholesterol synthesis, the level of hepatic cholesteryl esters, and the amount of cholesterol absorbed from the diet play no role in determining the rate of biliary cholesterol secretion, at least in this species. -Turley, S. D. , and J. M. Dietschy. Regulation of biliary cholesterol output in the rat: dissociation from the rate of hepatic cholesterol synthesis, the size of the hepatic cholesteryl ester pool, and the hepatic uptake of chylomicron cholesterol.
L'évaluation des stratégies de coping chez des patients asthmatiques

Selon le modele transactionnel du stress de Lazarus, l'individu, lorsqu'il fait face a une situation stressante, elabore des strategies d'ajustement specifiques appelees coping, ensemble organise et coherent de reponses cognitives, comportementales, emotionnelles et somatiques. Les strategies de coping habituellement utilisees par les sujets asthmatiques sont relativement peu connues. L'objectif de cette etude est d'evaluer les strategies de coping que les sujets utilisent en general. Nous avons administre le WCC (version abregee du questionnaire de Lazarus et Folkman) a 116 patients asthmatiques et 880 sujets sains francais adultes, des deux sexes. Une analyse en composantes principales, suivie de rotations varimax, a permis d'isoler trois facteurs rendant compte d'environ 68,2 % de la variance totale. Ils ont ete interpretes comme : coping centre sur le probleme, coping centre sur l'emotion, et recherche de soutien social. Les deux premieres dimensions sont proches de celles generalement decrites dans la litterature. Les patients asthmatiques utilisent davantage de strategies centrees sur l'emotion que le groupe controle. Ces resultats et leurs implications theoriques et pratiques sont discutees.
An SR-ISODATA algorithm for IDS alerts aggregation

Intrusion detection Systems(IDS) can produce large amount of alert data which usually possesses the characteristics of high redundancy and high repetition. Such kind of data makes the event processing for network security significantly difficult. Current cluster algorithms use cluster center to calculate the distance which leads to fairly big calculation errors. In order to aggregate the massive alert data effectively and identify important security events accurately, we propose an improved Iterative Self-Organizing Data Analysis Techniques Algorithm based on Similarity Radius (SR-ISODATA). In the presented algorithm, optimal sequence comparison method is used to calculate the attribute weight of alert data, and different similarity calculation methods are chosen due to different properties of alert data; the merging and splitting criteria are revised, the clustering center in the original ISODATA algorithm is replaced by the average similarity radius and the distance calculation in the original algorithm is replaced by the similarity. Extensive experiments using the alert experimental data on KDDCUP99 show that the SR-ISODATA algorithm gets a high alert compression rate and a higher purity of each cluster.
An Analytical Model for Random Changing Pseudonyms Scheme in VANETs

Changing pseudonyms are commonly accepted as one approach to protect location privacy in VANETs, but the effectiveness of most changing pseudonyms schemes have never been investigated rigorously. In this paper, we present a detailed analytical model based on a kind of simplest scheme, called Random Changing Pseudonyms (RCP), to quantify the level of location privacy provided by this scheme. Furthermore, according to the proposed model, we analyze and compare two special distributions, i.e., uniform discrete and age-based distributions. The results show that RCP scheme with uniform discrete distribution is better than with age-based distribution on protecting location privacy in VANETs. The accuracy of this model is verified by a set of simulations.
Evaluation of serum HER2 extracellular domain in early breast cancer patients: correlation with clinicopathological parameters and survival.

BACKGROUND We explored the correlation between serum human epidermal growth factor receptor-2 (HER2) extracellular domain (ECD) and tissue HER2 status, their relationship with clinicopathological parameters and their impact on disease-free survival (DFS) and overall survival in early breast cancer patients. PATIENTS AND METHODS This prospective trial included patients with stage I-III breast cancer. Serum HER2 ECD levels were measured by two enzyme-linked immunosorbent assays before surgical treatment. Tissue HER2 status was analyzed by immunohistochemistry (IHC) in all tumors; FISH assay was utilized in HER2 2+ tumors by IHC. RESULTS From May 2000 to July 2005, 256 consecutive stage I-III breast cancer patients were included in this study. High serum HER2 ECD levels (>or=15 ng/ml) were reported in 23 patients (9.0%) and HER2-positive status in tumor tissue was observed in 42 patients (16.4%) with a concordance of 87.1%. High HER2 ECD levels were significantly associated with high histological grade (P = 0.003), stage III (P = 0.008), lymph node involvement (P = 0.035) and negativity of both estrogen (P = 0.016) and progesterone (P = 0.007) receptors. At multivariate analysis, high serum HER2 ECD levels were a significant independent prognostic factor of worse DFS (P = 0.009). CONCLUSIONS A statistically significant association was observed between high serum HER2 ECD levels and worse DFS in early breast cancer patients.
A new complete heuristic approach for ant rendezvous problem

Ant meeting problem is a distributed problem that its purpose is to find an efficient path for ants to meet each other. Actually, ant robots suffer from the low memory and their restricted computational power. They communicate with their environment by leaving some symptoms like pheromones in their surroundings. In the problem of ants meeting, the ants should reach together in order to cooperate in an intelligent algorithm. In the common type of this problem, they start to search the environment without any knowledge about their locations, directions, obstacles and any other information. They can just leave some signs on the environment which shows their tracks. These marks are the only way of communication between ants. Also, these marks show the information about the ant which has passed the track, and every ant knows whose mark is that. In this paper, a new heuristic approach is proposed for the distributed ants meeting problem based on A* algorithm which guaranties the ants meeting in a finite time. Experimental results show that the presented algorithm is more efficient than previous ones.
Pengembangan Modul Bimbingan dan Konseling untuk Meningkatkan Kemampuan Komunikasi Interpersonal Siswa

This research aims to formulate guidance and counseling module to improve interpersonal communication ability of student s and to describe the level of applicability used by counselor. The method used was ADDIE model development. The properness test was done by three experts and the practicality test was done by three guidance and counseling teachers or counselors. The instruments used were skala likert, questionnaire and Focus Group Discussion (FGD). The data gathered in this research was analyzed by using descriptive statistic analysis and non-parametric statistic analysis . Based on these results, in general, it was concluded that the module developed was appropriate and could be used to help the students to improve their interpersonal
Multi-sequence memory with dynamic synapses and controllable steady-state period

Sequential information processing, for instance the sequence memory, plays an important role on many functions of brain. In the workings of the brain, the steady-state period is alterable. But in the existing sequence memory models using hetero-associations, the steady-state period is changeless in the sequence recall. In this paper, multi-sequence memory with controllable steady-state period is proposed. By introducing a novel exponential kernel sampling function and the sampling interval parameter, the steady-state period can be controlled, and the steady-state time steps is equal to the sampling interval parameter. Owing to introducing dynamic synapses into the sequence memory, we find that the sequence storage capacity can be enlarged.
Kurds HLA Genes: Its Implications in Transplantation and Pharmacogenomics

HLA genes (class I and II) have been studied in a Kurd population from Iran (North West towns of Saqqez and Baneh, close to Irak border). Kurds speak an Iranian language. HLA Kurd profile has been compared with those of Central Asians, Siberians, Mediterraneans and other worldwide populations; a total of 7746 chromosomes were used for computer comparisons. Both Neighbor-joining and correspondence genetic analyses place Kurds in the Mediterranean population cluster, close to Iranians, Europeans and Caucasus populations (Svan and Georgian). New extended HLA haplotypes are described, being A*02:01-B*35:01-DRB1*01:01-DQB1*05:01 and A*24:02-B*18:09-DRB1*11:01- DQB1*03:01 the most frequent ones; other Kurd extended haplotypes are also found in Azeris and Palestinians. This research work may be useful for: 1) future Iranian Kurds transplantation regional programs, 2) HLA pharmacogenomics in order to practise a preventive Medicine and drug side effects, and 3) Epidemiology of HLA-associated diseases in Kurds.
Using Convolutional Neural Networks for Content Extraction from Online Flyers

The rise of online shopping has hurt physical retailers, which struggle to persuade customers to buy products in physical stores rather than online. Marketing flyers are a great mean to increase the visibility of physical retailers, but the unstructured offers appearing in those documents cannot be easily compared with similar online deals, making it hard for a customer to understand whether it is more convenient to order a product online or to buy it from the physical shop. In this work we tackle this problem, introducing a content extraction algorithm that automatically extracts structured data from flyers. Unlike competing approaches that mainly focus on textual content or simply analyze font type, color and text positioning, we propose a new approach that uses Convolutional Neural Networks to classify words extracted from flyers typically used in marketing materials to attract the attention of readers towards specific deals. We obtained good results and a high language and genre independence.
Global Journal of Computer Science and Technology P a g e | 44 A Framework for Systematic Database

It is currently the norm that relational database designs should be based on a normalized logical data model. The primary objective of this design technique is data integrity and database extendibility. The Third Normal Form is regarded by academicians and practitioners alike to be point at which the database design is most efficient. Unfortunately, even this lower level normalization form has a major drawback with regards to query evaluation. Information retrievals from the database can result in large number of joins which degrades query performance. So you need to sometimes break theoretical rules for real world performance gains. Most existing Conceptual Level RDBMS data models provide a set of constructs that only describes ―what data is used‖ and does not capture ―how the data is being used‖. The question of ―how data is used‖ gets embedded in the implementation level details. As a result, every application built on the existing database extracts the same or similar data in different ways. If the functional use of the data is also captured, common query evaluation techniques can be formulated and optimized at the design phase, without affecting the normalized database structure constructed at the Conceptual Design phase. This paper looks at denormalization as an effort to improve the performance in data retrievals made from the database without compromising data integrity. A study on a hierarchical database table shows the performance gain with respect to response time – using a denormalization technique.
AIS Electronic

Since 2000, enterprise resource planning (ERP) systems have been widely adopted by large, state-owned companies in China. While there is a rich body of literature on ERP implementation in western companies, studies of Chinese companies are scarce. A recent exception is a study of seventy seven mostly manufacturing companies in China by Liang et al. (2007). They found that high coercive institutional pressures positively affect top management participation, which, in turn, positively affect ERP diffusion and the degree of its usage across the organisation. However, how the institutional pressures are exercised and what are the roles of top management in ERP implementation in complex Chinese companies remained open questions, worthy of further examination. The lack of understanding of specific conditions and especially dynamics of power relations in ERP implementation motivated our in-depth case study of a multi-site ERP system implementation in a large Chinese manufacturing company. The data collected from three divisions/subsidiaries shows that their implementation of ERP system turned out to have different outcomes. The key issues that emerged from the data indicate that the dynamics of power relations between the parent company and divisions/subsidiaries, and IT context have had a significant influence on the ERP implementation and different outcomes in divisions/subsidiaries.
A Novel Method for Automatic Treadmill Speed Adaptation

Robot-aided treadmill training is an innovative rehabilitation method for patients with locomotor dysfunctions. However, in current rehabilitation systems treadmill speed is restricted to constant values or adjusted by the therapist, whereas self-determined phases of accelerations and decelerations cannot be performed by the patient in an interactive and intuitive way. We present a new approach that allows treadmill walking with intuitive gait speed adaptation. In this approach, the user's trunk position is fixed in walking direction. The horizontal interaction forces applied by the user intending to accelerate or decelerate the gait are measured at the trunk connection and fed to the treadmill controller. The desired gait acceleration is calculated by means of a virtual admittance. Integration yields the desired speed which is fed into the underlying velocity controller of the treadmill. The method was verified by two experimental setups and tested on ten healthy subjects. In one setup, the subject's trunk was rigidly connected by a tether, whereas in the second setup the subject was placed in a robotic gait orthosis. All subjects were able to use both systems immediately and intuitively. The treadmill speed profile during the gait cycle corresponds to that of normal walking. The controller can be extended to simulate different walking conditions, such as slope walking. The method can be used for patient-cooperative control strategies performed with a robotic gait orthosis as well as for any other user-interactive applications in fitness and sports.
Cross-Whisker Adaptation of Neurons in the Rat Barrel Cortex

Neurons in the barrel cortex and the thalamus respond preferentially to stimulation of one whisker (the principal whisker) and weakly to several adjacent whiskers. Cortical neurons, unlike thalamic cells, gradually adapt to repeated whisker stimulations. Whether cortical adaptation is specific to the stimulated whisker is not known. The aim of this intracellular study was to determine whether the response of a cortical cell to stimulation of an adjacent whisker would be affected by previous adaptation induced by stimulation of the principal whisker and vice versa. Using a high-frequency stimulation that causes substantial adaptation in the cortex and much less adaptation in the thalamus, we show that cortical adaptation evoked by a train of stimuli applied to one whisker does not affect the synaptic response to subsequent stimulation of a neighboring whisker. Our data indicate that intrinsic mechanisms are not involved in cortical adaptation. Thalamic recordings obtained under the same conditions demonstrated that an adjacent whisker response was not generated in the thalamus, indicating that the observed whisker-specific adaptation results from diverging thalamic inputs or from cortical integration.
Emergent Majorana mass and axion couplings in superfluids

Axions (in the general sense) may acquire qualitatively new couplings inside superfluids. Their conventional couplings to fermions, in empty space, involve purely imaginary masses; the new couplings involve emergent Majorana masses. A generalized concept of Majorana mass is proposed, which allows continuous interpolation between Majorana and Dirac fermions, and also extension to bosons. The possibility of weak links for axions, recently put forward, is analyzed and replaced with a non-local analogue.
Efficient Detection, Quantification and Enrichment of Subtle Allelic Alterations

Gene targeting (GT) can introduce subtle alterations into a particular locus and represents a powerful tool for genome editing. Engineered zinc finger nucleases (ZFNs) are effective for generating minor allelic alterations. Efficient detection of such minor alterations remains one of the challenges in ZFN-mediated GT experiments. Here, we report the establishment of procedures allowing for efficient detection, quantification and enrichment of such subtle alterations. In a biallelic model, polyacrylamide gel electrophoresis (PAGE) is capable of detecting rare allelic variations in the form of DNA heteroduplexes at a high efficiency of ∼0.4% compared with ∼6.3% by the traditional T7 endonuclease I-digestion and agarose gel electrophoresis. In a multiple allelic model, PAGE could discriminate different alleles bearing addition or deletion of 1–18 bp as distinct bands that were easily quantifiable by densitometry. Furthermore, PAGE enables enrichment for rare alleles. We show for the first time that direct endogenous GT is possible in medaka by ZFN RNA injection, whereas PAGE allows for detection and cloning of ZFN-targeted alleles in adults arising from ZFN-injected medaka embryos. Therefore, PAGE is effective for detection, quantification and enrichment of multiple fine allelic differences and thus offers a versatile tool for screening targeted subtle gene alterations.
Who should review this change?: Putting text and file location analyses together for more accurate recommendations

Software code review is a process of developers inspecting new code changes made by others, to evaluate their quality and identify and fix defects, before integrating them to the main branch of a version control system. Modern Code Review (MCR), a lightweight and tool-based variant of conventional code review, is widely adopted in both open source and proprietary software projects. One challenge that impacts MCR is the assignment of appropriate developers to review a code change. Considering that there could be hundreds of potential code reviewers in a software project, picking suitable reviewers is not a straightforward task. A prior study by Thongtanunam et al. showed that the difficulty in selecting suitable reviewers may delay the review process by an average of 12 days. In this paper, to address the challenge of assigning suitable reviewers to changes, we propose a hybrid and incremental approach Tie which utilizes the advantages of both Text mIning and a filE location-based approach. To do this, Tie integrates an incremental text mining model which analyzes the textual contents in a review request, and a similarity model which measures the similarity of changed file paths and reviewed file paths. We perform a large-scale experiment on four open source projects, namely Android, OpenStack, QT, and LibreOffice, containing a total of 42,045 reviews. The experimental results show that on average Tie can achieve top-1, top-5, and top-10 accuracies, and Mean Reciprocal Rank (MRR) of 0.52, 0.79, 0.85, and 0.64 for the four projects, which improves the state-of-the-art approach RevFinder, proposed by Thongtanunam et al., by 61%, 23%, 8%, and 37%, respectively.