Miracle-dz/UniFAR-FTUs huggingface dataset:
Electrical conductivity and soybean seedling emergence

A avaliacao do vigor e sua relacao com a emergencia de plântulas em campo e fundamental para a estimativa correta do potencial fisiologico de sementes de soja [Glycine max (L.) Merrill]. O presente trabalho objetivou verificar a relacao entre os resultados do teste de condutividade eletrica (CE) e os da emergencia de plântulas de soja em campo e em laboratorio. Foram estudados niveis de disponibilidade de agua no substrato -0,03; -0,2; -0,4; e -0,6 MPa. Foram avaliados 14 lotes de sementes das cultivares Embrapa 48 e BRS 133. O experimento em campo foi conduzido em tres epocas de semeadura (26/11 e 3 e 10/12/2000); em laboratorio, foram determinados o teor de agua, antes e apos o envelhecimento acelerado (EA) das sementes, a germinacao e o vigor (testes de EA e de CE). A reducao progressiva da quantidade de agua no substrato provocou diminuicao das porcentagens de germinacao e de emergencia de plântulas em laboratorio, de modo que o desempenho germinativo das sementes dependeu dos niveis de estresse hidrico e do vigor da semente. Para lotes de maior vigor da cultivar Embrapa 48, o melhor desempenho ocorreu sob o potencial hidrico de -0,6 MPa. CE pode ser um eficiente procedimento para a avaliacao do potencial fisiologico e desempenho de lotes de sementes de soja, necessitando, porem, que estudos adicionais sejam conduzidos para o estabelecimento de valores ou limites de valores para caracterizar o nivel de vigor das sementes (alto, medio ou baixo) permitindo direcionar de maneira consistente o uso dos lotes de sementes.
Using Machine Learning for Data Center Cooling Infrastructure Efficiency Prediction

Power consumption continues to remain a critical aspect for High Performance Computing (HPC) data centers. It becomes even more crucial for Exascale computing since scaling today's fastest system to an Exaflop level would consume more than 168 MW power which is 8 times higher than the 20 MW power consumption goal set, at the time of this publication, by the US Department of Energy. This naturally leads to a necessity for energy efficiency improvement that will encompass the full chain of the power consumers, starting from the data center infrastructure, including cooling overheads and electrical losses, up to compute resource scheduling and application scaling. In this paper a machine learning approach is proposed to model the Coefficient of Performance (COP) of HPC data center's hot water cooling loop. The suggested model is validated on operational data obtained at Leibniz Supercomputing Centre (LRZ). The paper shows how this COP model can help to improve the energy efficiency of modern HPC data centers.
Real Time Vertex Based Deformation in Training Simulator

Soft tissue simulation is very important in medical simulation and learning procedures. But such simulations require intensive computation. With the force feedback devices, the computation required should be much faster as touch sensation is approximately 20 times faster than that of visual. In this paper an efficient Vertex based algorithm for visual deformation is presented. Visual deformation of linear, isotropic and homogenous triangular mesh soft model is achieved by modifying a slope intercept equation of a line which is used to get a new position for the point contacted through a tip of a force feedback device. Haptic sensation is achieved using Hooke's law which is coupled with visual deformation based on our proposed algorithm. In our simulation we use up to 20K of triangles for object representation.
Ligand release mechanisms and channels in histone deacetylases

Exploring the molecular channels of class I histone deacetylases (HDACs) with buried active sites are important to understand their structures and functionalities. In this work, we perform hybrid classical molecular dynamics and random acceleration molecular dynamics simulations to explore the B3N [i.e., (4‐(dimethylamino)N‐[7(hydroxyamino)‐7‐oxoheptyle] benzamide)] exit channels in the x‐ray crystal structures of HDAC3 and HDAC8 enzymes. Our simulations identify B3N release through four different channels in HDAC3 (denoted as A1, A2, B1, and B2) and HDAC8 (referred as A1, B1, B2, and B3) enzymes, among which egression through channel A1 is more predominant in both the enzymes. This mechanism is similar to ligand release in HDAC1 and HDAC2 described in our previous study and can be the fingerprint ligand release mechanisms in class I HDACs. Ligand release events through B channels, on the other hand, are different among HDAC3 and HDAC8, highlighting the significances of substituted residues in controlling the access to these channels This study reveals a novel aromatic gating mechanism elicited by TYR154‐TRP141‐TYR111 that controls the B3N access to all the B channels in HDAC8. The TRP141 in HDAC8 is substituted by LEU133 in HDAC3, which do not hinder the access to B channels in HDAC3. However, two hydrogen bonded barricades formed as ARG28‐GLY297‐GLY295‐GLY131 and TRP129‐ARG28‐ALA130‐LEU29‐TRP129 obstruct the B3N from exploring the B channels in HDAC3. The structural and dynamical characterizations of molecular channels and ligand unbinding mechanisms reported in this study provide novel structural insights and atomic level perspectives on HDAC3 and HDAC8 enzymes, thereby potentially aiding in the design of more specific HDAC inhibitors.Copyright © 2013 Wiley Periodicals, Inc.
Inward rectifier current noise in frog skeletal muscle.

Inwardly rectifying K+ currents were studied in cut muscle fibres from frogs using the Vaseline‐gap voltage‐clamp method. Both faces of the membrane were exposed to 120 mM‐K+ methylsulphate solution. At small negative potentials, ‐10 and ‐21 mV, the current noise spectrum, after subtraction of a control spectrum at the zero current potential, could be fitted by a Lorentzian spectral component, usually with an additional 1/f component, where f is the frequency. At more negative potentials the 1/f component predominated. The zero frequency amplitude of the Lorentzian averaged 2.6 X 10(‐24) A2 Hz‐1 at ‐10 mV and 4.6 X 10(‐24) A2 Hz‐1 at ‐21 mV, with a mean half‐power frequency, fc, of 34 Hz and 45 Hz, respectively. The time constant of the K+ current activation upon hyperpolarization agrees with that calculated from fc, and the Lorentzian disappears upon replacement of external K+ by tetraethylammonium (TEA+) or Rb+. Thus, the Lorentzian component appears to be ascribable to fluctuations originating in the inwardly rectifying mechanism. The noise spectra and macroscopic currents were interpreted by assuming that the inwardly rectifying K+ conductance is proportional to the product of two parameters: ps representing the state of the mechanism that gives rise to the observable macroscopic current relaxations and to the current fluctuations resulting in the observed Lorentzian spectra, and pf describing the instantaneous rectification of the single‐channel conductance. Alternatively, pf may represent another mechanism in series with ps, but which fluctuates too rapidly to measure. Using this model the limiting single‐channel conductance, gamma, was found to be approximately 9 pS. The corresponding specific density of channels is about 1 micron‐2, assuming uniform distribution over all regions of the membrane. A preliminary value for gamma ( DeCoursey & Hutter , 1982) was derived without consideration of instantaneous rectification. Systematic errors in these results due to voltage decrement in the T‐tubules are evaluated in an Appendix, and are found to be tolerably small in the voltage range studied.
Semantic Textual Similarity for Machine Translation Evaluation

Machine translation translates a speech of text from the source language to target language. This paper introduces machine translation evaluation by calculating the semantic textual similarity between the machine translated sentences. The similarity score varies by using different values of alpha, beta and ranges semantic similarity [0,5]. The experiment is carried out on SemEval 2017 datasets. The experiment resulted in the highest accuracy for the Spanish-Spanish dataset with Pearson coefficient correlation 0.7969.
An echographic evaluation during the early puerperium of the uterine wound after caesarean section

Serial echographic evaluation of the uterine wound after lower uterine segment caesarean section was performed on 48 puerperal patients. Similar examinations after vaginal delivery were carried out on 14 puerperal patients. The aim of this study was to determine whether evidence of abnormal healing could be detected by this method. Although three distinctive patterns were noted, no correlation with clinical findings could be made and no conclusions could be drawn.
Relationship Satisfaction, PTSD Symptom Severity, and Mental Healthcare Utilization Among OEF/OIF Veterans

Despite the availability of evidence-based PTSD treatments at most facilities within the VA Healthcare System, most Iraq and Afghanistan veterans returning from deployments with posttraumatic stress symptoms do not receive an adequate dose of mental health treatment, prompting the need to identify potential barriers to or facilitators of mental health care utilization. Previous research demonstrated self-reported mental health care utilization in the prior year varies as a function of PTSD symptom severity, and the interaction of PTSD symptom severity and romantic relationship satisfaction (Meis et al., 2010). We extended these findings by objectively measuring the degree of utilization over a 1-year period (i.e., number of sessions attended) in a sample of 130 Iraq and Afghanistan veterans who presented to primary care/deployment health and completed an initial mental health evaluation. Results indicated main and interactive effects of PTSD symptom severity and relationship satisfaction, such that greater PTSD symptom severity was associated with greater utilization at average to high relationship satisfaction (p < .05), but not low relationship satisfaction. Implications for future research and couple/family based interventions for veterans with PTSD are discussed.
Game of Organizing International Cricket: Co-Existence of Country-Line and Club-Line Games

Abstract The paper presents an economic model of interaction between cricket boards, players and international club-line games sponsors like ICL or IPL. It attempts to capture the inherent conflict between such games and country-line games traditionally organized by cricket boards. It identifies the nature of various trade offs facing these ‘players’ in the game and examines the effects of market-size changes on the composition of players, the scale of country-line and club-line games and the welfare of players and cricket boards.
Automated Histogram-Based Brain Segmentation in T1-Weighted Three-Dimensional Magnetic Resonance Head Images

Current semiautomated magnetic resonance (MR)-based brain segmentation and volume measurement methods are complex and not sufficiently accurate for certain applications. We have developed a simpler, more accurate automated algorithm for whole-brain segmentation and volume measurement in T(1)-weighted, three-dimensional MR images. This histogram-based brain segmentation (HBRS) algorithm is based on histograms and simple morphological operations. The algorithm's three steps are foreground/background thresholding, disconnection of brain from skull, and removal of residue fragments (sinus, cerebrospinal fluid, dura, and marrow). Brain volume was measured by counting the number of brain voxels. Accuracy was determined by applying HBRS to both simulated and real MR data. Comparing the brain volume rendered by HBRS with the volume on which the simulation is based, the average error was 1.38%. By applying HBRS to 20 normal MR data sets downloaded from the Internet Brain Segmentation Repository and comparing them with expert segmented data, the average Jaccard similarity was 0.963 and the kappa index was 0.981. The reproducibility of brain volume measurements was assessed by comparing data from two sessions (four total data sets) with human volunteers. Intrasession variability of brain volumes for sessions 1 and 2 was 0.55 +/- 0.56 and 0.74 +/- 0.56%, respectively; the mean difference between the two sessions was 0.60 +/- 0.46%. These results show that the HBRS algorithm is a simple, fast, and accurate method to determine brain volume with high reproducibility. This algorithm may be applied to various research and clinical investigations in which brain segmentation and volume measurement involving MRI data are needed.
Environment-quality management coalignment across industrial contexts: an empirical investigation of performance implications

In recent years, many firms have decided to implement Quality Management (QM), persuaded by its numerous benefits and its competitive potential. In fact, in Europe the number of firms that have obtained and registered quality systems has grown spectacularly. Nevertheless, to what point can the industry’s structural elements limit the implementation of quality management and the performance obtained? Our paper introduces the strategic and industrial visions to determine how environments with different structural characteristics require different degrees of QM implementation to achieve financial, operational and employee performance. To test our goals, we gathered a sample of 273 European managers. We presented 16 different factors of competitive structure to members of the sample and elicited their likelihood of implementing different QM practices. The results show that the degree of implementation of QM practices depends on the structural characteristics of the environments in which the firms develop their activity. It is thus possible to establish the most appropriate configurations for each kind of sector
Supertemporal resolution of functional MRI timecourse data

High temporal resolution is critical in understanding the faster evolving processes in the blood oxygenation level dependent (BOLD) response used in functional magnetic resonance imaging. However, sampling rates faster than the T1 relaxation rate may introduce distortions of the measured BOLD signal due to spin saturation and blood inflow effects. We have developed a technique called the supertemporal resolution (STR) method that exploits the slice timing characteristics in two-dimensional echoplanar imaging in a novel way to obtain a higher sampling rate than the nominal TR allows. This method, by maintaining constant TR, increases temporal resolution without sacrificing signal-to-noise ratio and avoids distortions in the measured signal.
Localisation of body-worn sensors applying Ultra Wideband technology

This paper presents a study of 3D human body localisation using Ultra Wideband technology. Cube and Y shape base station configurations, time of arrival and first peak detection algorithms are used to estimate the position of the sensors that are placed near the surface of the body. Also spherical coordinate system is used to find the direction of the target. A comparative study is done between the TOA and TDOA method in terms of accuracy obtained in estimation of known coordinates. Results show that accuracy in estimation of location of the sensor depends on position it is placed on the human body as the presence of body would cause interference. The overall average accuracy in 3D localisation is around 2.5 to 4.5 cm for TOA method and 3.5 to 4.5 cm for TDOA method.
The connective tissue graft: a comparative clinical evaluation of wound healing at the palatal donor site. A preliminary study.

OBJECTIVES The aim of this study is to evaluate early healing results of the palatal wound by comparing three different surgical procedures for harvesting a connective tissue graft: the single-incision (SI), the free gingival graft (FGG) and the trap-door (TD) techniques. MATERIAL AND METHODS 36 patients requiring a root coverage procedure were selected for treatment using a bilaminar technique and randomly assigned (12 per group) to the FGG, TD or SI groups. The size of the graft was standardised to 12 x 8 mm and the thickness ranged from 1 to 1.5 mm. The following parameters were recorded at 1, 2, 3, 4, 6 and 8 weeks postsurgery: immediate and delayed bleeding (iB, dB), sensibility (S), complete epithelialisation (CE), discomfort (D), and variation of feeding habits (FH). RESULTS The difference in CE between the SI and FGG groups was statistically significant at the third postoperative week (100% and 50%, respectively). The discomfort rate at the first week postsurgery was the same in the SI and TD groups (50% without discomfort), but results were statistically significant different in the FGG group (0% without discomfort). No significant differences were found between the three groups for the other parameters. CONCLUSIONS Statistically significant differences were found between the SI and FGG techniques in terms of CE, which occurred faster in the SI group. The discomfort rate recorded for both SI and TD groups was significantly lower than for FGG group. No marked differences were noted between SI and TD procedures. The latter was confirmed by patient interviews. The results of this preliminary study have little statistical significance because of the limited number of patients but they represent an important basis for a comparative clinical study, with a larger sample of participants, which is currently in progress.
Commons-based peer production and artistic expression: Two cases from Greece

This essay narrates, from a creator-observation perspective, the production of two works of fiction, a book of short stories and a play, based on the principles and technologies of Commons-based peer production. This is potentially interesting from both the Commons-based peer production and the literary perspective. Even though both seem well-matched by their prima facie lack of profit orientation, Commons-based peer production case studies rarely deal with fiction, and regarding plays, artistic creativity is still mostly associated with one, maybe two authors. After tracing and analysing the Commons-based peer production phenomenon, the case studies show concretely the fate of the specific projects as well as how, nowadays, people can get involved in collaborative artistic projects inspired and catalysed by Commons-oriented principles and technologies.
CD43 Functions as an E-Selectin Ligand for Th17 Cells In Vitro and Is Required for Rolling on the Vascular Endothelium and Th17 Cell Recruitment during Inflammation In Vivo

Endothelial E- and P-selectins mediate lymphocyte trafficking in inflammatory processes by interacting with lymphocyte selectin ligands. These are differentially expressed among different T cell subsets and function alone or in cooperation to mediate T cell adhesion. In this study, we characterize the expression and functionality of E-selectin ligands in Th type 17 lymphocytes (Th17 cells) and report that CD43 functions as a Th17 cell E-selectin ligand in vitro that mediates Th17 cell rolling on the vascular endothelium and recruitment in vivo. We demonstrate Th17 cells express CD44, P-selectin glycoprotein ligand (PSGL)-1, and CD43. Few PSGL-1−/−CD43−/− Th17 cells accumulated on E-selectin under shear flow conditions compared with wild-type cells. CD43−/− Th17 cell accumulation on E-selectin was impaired as compared with wild-type and PSGL-1−/−, and similar to that observed for PSGL-1−/−CD43−/− Th17 cells, indicating that CD43 alone is a dominant ligand for E-selectin. Notably, this finding is Th17 cell subset specific because CD43 requires cooperation with PSGL-1 in Th1 cells for binding to E-selectin. In vivo, Th17 cell recruitment into the air pouch was reduced in CD43−/− mice in response to CCL20 or TNF-α, and intravital microscopy studies demonstrated that CD43−/− Th17 cells had impaired rolling on TNF-α–treated microvessels. Furthermore, CD43−/− mice were protected from experimental autoimmune encephalomyelitis and had impaired recruitment of Th17 cells in the spinal cord. Our findings demonstrate that CD43 is a major E-selectin ligand in Th17 cells that functions independent of PSGL-1, and they suggest that CD43 may hold promise as a therapeutic target to modulate Th17 cell recruitment.
Bispecific Monoclonal Antibodies Produced by Somatic Cell Fusion Increase the Potency of Tissue Plasminogen Activator

Summary Bispecific monoclonal antibodies that bind simultaneously to human fibrin and tissue plasminogen activator (tPA) enhance the fibrinolytic potency of tPA. Two bispecific antibodies (F36.23 and F32.1) were generated by somatic cell fusion. Antibody F36.23 derives its tPA binding from monoclonal anti-tPA antibody TCL8 and its fibrin binding from monoclonal antifibrin antibody 59D8. After purification from cell supernatants and ascites by two steps of affinity chromatography, hybrid-hybridoma bispecific antibody F36.23 simultaneously bound tPA and fibrin in solution and in solid-phase assays. In an assay for the lysis of human fibrin monomer, F36.23 increased the fibrinolytic potency of tPA by 5 to 10 fold, regardless of whether the bispecific antibody had been combined with the tPA before or during the assay. Bispecific F36.23 F(ab′)2 also bound tPA and fibrin simultaneously, and the enhancement in fibrinolysis in the presence of F36.23 F(ab′)2 was identical to that in the presence of intact F36.23. The second bispecific antibody, F32.1, was produced by an alternative strategy that has a wider potential for applicaton in other systems. Hybridoma bispecific antibody F32.1 was derived from the fusion of immune splenocytes (in mice immunized with a synthetic oligopeptide representing the amino terminus of the α-chain of human fibrin) with the anti-tPA cell line TCL8. The properties of hybridoma bispecific antibody F32.1 and its F(ab′)2 were indistinguishable from those of hybrid-hybridoma bispecific antibody F36.23 in solid-phase binding assays and in assays of fibrinolysis. Bispecific antibodies produced by somatic cell fusion, particularly in the form of F(ab′)2, may have potential for use in clinical thrombolysis.
Thrombotic Thrombocytopenic Purpura

Recent studies indicate that CRTTP patients have excessive shear stress-induced platelet aggregation that is associated with the presence of ULvWF multimers in their plasma and increased vWF-binding to their platelets by flow cytometry. In these CRTTP patients, relapses, excessive shear-aggregation and the presence in their plasma of ULvWF forms are all reversed by the infusion of normal FFP or substances devoid of the largest vWF multimers found in plasma (cryoprecipitate-poor plasma or cryosupernatant; solvent/detergent-treated plasma) without the need for concurrent plasmapheresis. This constellation of observations, along with reports of increased vWF in TTP platelet thrombi, increases the probability that ULvWF multimers derived from injured or abnormal endothelial cells induce aggregation during TTP episodes in high-shear regions of the microcirculation.