Miracle-dz/UniFAR-FTUs huggingface dataset:
Psychological and relational correlates of intimate partner violence profiles among pregnant adolescent couples.

We sought to identify relationship and individual psychological factors that related to four profiles of intimate partner violence (IPV) among pregnant adolescent couples: no IPV, male IPV victim only, female IPV victim only, mutual IPV, and how associations differ by sex. Using data from a longitudinal study of pregnant adolescents and partners (n = 291 couples), we used a multivariate profile analysis using multivariate analysis of covariance with between and within-subjects effects to compare IPV groups and sex on relationship and psychological factors. Analyses were conducted at the couple level, with IPV groups as a between-subjects couple level variable and sex as a within-subjects variable that allowed us to model and compare the outcomes of both partners while controlling for the correlated nature of the data. Analyses controlled for age, race, income, relationship duration, and gestational age. Among couples, 64% had no IPV; 23% male IPV victim only; 7% mutual IPV; 5% female IPV victim only. Relationship (F = 3.61, P < .001) and psychological (F = 3.17, P < .001) factors differed by IPV group, overall. Attachment anxiety, attachment avoidance, relationship equity, perceived partner infidelity, depression, stress, and hostility each differed by IPV profile (all P < .01). Attachment anxiety, equity, depression and stress had a significant IPV profile by sex interaction (all P < .05). Couples with mutual IPV had the least healthy relationship and psychological characteristics; couples with no IPV had the healthiest characteristics. Females in mutually violent relationships were at particularly high risk. Couple-level interventions focused on relational issues might protect young families from developing IPV behaviors. Aggr. Behav. 43:26-36, 2017. © 2016 Wiley Periodicals, Inc.
Classification of ADLs using muscle activation waveform versus thirteen EMG features

Movement classification has been a challenging problem in neuroprosthesis control. Many studies have taken into account the classification of movement using time and frequency domain features extracted from the electromyogram signals while calculating these features are usually time consuming. In this paper, we compared the capability of muscle activation waveform in the classification of five arm movements during activities of daily living, also known as ADLs, versus 13 different prevalent electromyogram features. We tested our technique on the electromyogram signal recorded from six healthy male right handed subjects. We, also, selected the muscles that are supposed to be the intact muscles in a tetraplegic spinal cord injury patient. Our results indicated that there exists significant higher accuracy with recruiting muscle activation waveform in classification, while the complexity of calculating features is eliminated.
Phenotypic Alteration and Target Gene Identification Using Combinatorial Libraries of Zinc Finger Proteins in Prokaryotic Cells

ABSTRACT We have developed a method with prokaryotic organisms that uses randomized libraries of zinc finger-containing artificial transcription factors to induce phenotypic variations and to identify genes involved in the generation of a specific phenotype of interest. Combining chromatin immunoprecipitation experiments and in silico prediction of target DNA binding sequences for the artificial transcription factors, we identified ubiX, whose down-regulation correlates with the thermotolerance phenotype in Escherichia coli. Our results show that randomized libraries of artificial transcription factors are powerful tools for functional genomic studies.
Ethyl 5-methyl-4-oxo-3-phenyl-2-propylamino-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylate

The title compound, C19H21N3O3S, was synthesized via the aza-Wittig reaction of functionalized iminophosphorane with phenyl isocyanate under mild conditions. In the molecule, the fused thienopyrimidine ring system is essentially planar, with a maximum deviation of 0.072 (2) Å, and makes a dihedral angle of 60.11 (9)° with the phenyl ring. An intramolecular C—H⋯O hydrogen bond is present. The crystal packing is stabilized by intermolecular N—H⋯O and C—H⋯O hydrogen bonds.
An interventional Soylent diet increases the Bacteroidetes to Firmicutes ratio in human gut microbiome communities: a randomized controlled trial

Our knowledge of the relationship between the gut microbiome and health has rapidly expanded in recent years. Diet has been shown to have causative effects on microbiome composition, which can have subsequent implications on health. Soylent 2.0 is a liquid meal replacement drink that satisfies nearly 20% of all recommended daily intakes per serving. This study aims to characterize the changes in gut microbiota composition resulting from a short-term Soylent diet. Fourteen participants were separated into two groups: 5 in the regular diet group and 9 in the Soylent diet group. The regular diet group maintained a diet closely resembling self-reported regular diets. The Soylent diet group underwent three dietary phases: A) a regular diet for 2 days, B) a Soylent-only diet (five servings of Soylent daily and water as needed) for 4 days, and C) a regular diet for 4 days. Daily logs self-reporting diet, Bristol stool ratings, and any abdominal discomfort were electronically submitted. Eight fecal samples per participant were collected using fecal sampling kits, which were subsequently sent to uBiome, Inc. for sample processing and V4 16S rDNA sequencing. Reads were clustered into operational taxonomic units (OTUs) and taxonomically identified against the GreenGenes 16S database. We find that an individual’s alpha-diversity is not significantly altered during a Soylent-only diet. In addition, principal coordinate analysis using the unweighted UniFrac distance metric shows samples cluster strongly by individual and not by dietary phase. Among Soylent dieters, we find a significant increase in the ratio of Bacteroidetes to Firmicutes abundance, which is associated with several positive health outcomes, including reduced risks of obesity and intestinal inflammation.
A Data-Driven Design for Deriving Usability Metrics

The complexity of Enterprise Information Systems can be overwhelming to users, yet they are an often overlooked domain for usability research. To better understand the ways in which users interact with these systems, we have designed an infrastructure for input logging that is built upon a data model relating system components, user inputs, and tasks. This infrastructure is aware of user representations, task representations, and the history of user interactions. The interface components themselves log user inputs, so that timing data and action events are automatically aligned and are linked to specific tasks. The knowledge gained about user interactions at varying levels of granularity, ranging from keystroke analysis to higher-level task performance, is a valuable resource for both assessing and enhancing system usability.
What's gender got to do with it? Examining masculinities, health and safety and return to work in male dominated skilled trades.

BACKGROUND Electrical injuries are a common cause of work-related injury in male dominated skilled trades. OBJECTIVES In this study we explored how issues of gender, masculinities and institutional workplace practices shape expectations of men and their choices when returning to work following a workplace electrical injury. METHODS Twelve workers, who suffered an electrical injury, and twelve employer representatives, completed semi-structured interviews. Using thematic analysis we identified key themes related to how masculinities influenced men's health and safety during the return to work process. RESULTS Strong identification with worker roles can influence injured workers decisions to return to work 'too early'. A desire to be viewed as a strong, responsible, resilient worker may intersect with concerns about job loss, to influence participants' decisions to not report safety issues and workplace accidents, to not disclose post-injury work challenges, and to not request workplace supports. Institutionalized workplace beliefs regarding risk, de-legitimization of the severity of injuries, and the valorization of the "tough" worker can further re-enforce dominant masculine norms and influence return to work processes and health and safety practices. CONCLUSIONS Workplaces are key sites where gender identities are constructed, affirmed and institutionalized. Further research is warranted to examine how established masculine norms and gendered workplace expectations can influence workplace health and safety in male dominated high risk occupations. Future research should also evaluate strategies that encourage men to discuss post-injury work challenges and request supports when work performance or health and safety issues arise during the return to work process.
History of Phytophthora cinnamomi management in Western Australia

Phytophthora cinnamomi has recently been recognized as a key threatening process to biodiversity in Australia. The impact of this introduced microscopic water mould on destruction of forests and heath land communities has been observed since 1921 in southwestern Australia. It took over 40 years for the causal agent to be identified in 1964. Over the next 40 years, State Government Departments formulated policy and implemented management measures to deal with the problem. These measures have changed greatly over time as new knowledge about the host range and extent of the epidemic have become available. Unfortunately, the pathogen had spread over large areas of estate prior to the identification of the causal agent and the development of a management response. The spread of P.cinnamomi into significant areas of the conservation estate, including biodiversity hotspots, highlights the urgency of ensuring that Phytophthora dieback and its management is adequately resourced and is underpinned by appropriate research and communication programs. This review describes the main historical events leading up to the formulation of the 2004 State Phytophthora Dieback Response Framework. These include: quarantining half a million hectares of State Forest in 1976/7 in order to map the extent of the disease and implement hygiene measures; developing policy and management practices for the conservation estate; the acceptance by the Hon. Minister for the Environment in 1996 of the 33 recommendations in the WA Dieback Review Panel Report; the establishment of community based Dieback Working Groups; the preparation of the National Threat Abatement Plan in 2001, and in 2004 the development of National Best Practices Management Guidelines and a risk assessment methodology suitable for national adoption. In spite of these actions, much remains to be done. Flora and fauna remain threatened by the continued expansion and impact of Phytophthora dieback. We have few tools available to reduce the extension, spread and impact of the pathogen and the diseases it causes. The community needs to be better informed of the direct and indirect impacts this disease has had on individual species and ecosystem function and health, and encouraged to take greater ownership of an environmental problem that encompasses all types of land tenure. Recent developments in policy development are encouraging but need to be underpinned by much further research and collaboration.
Enabling Data-Driven Optimization of Quality of Experience for Internet Applications

Todays Internet has become an eyeball economy dominated by applications such as video streaming and VoIP. With most applications relying on user engagement to generate revenues, maintaining high user-perceived QoE (Quality of Experience) has become crucial to ensure high user engagement. For instance, one short buffering interruption leads to 39% less time spent watching videos and causes significant revenue losses for ad-based video sites. Despite increasing expectations for high QoE, existing approaches have limitations to achieve the QoE needed by todays applications. They either require costly re-architecting of the network core, or use suboptimal endpointbased protocols to react to the dynamic Internet performance based on limited knowledge of the network. In this talk, I will present a new approach, which is inspired by the recent success of data-driven approaches in many fields of computing. I will demonstrate that data-driven techniques can improve Internet QoE by utilizing a centralized real-time view of performance across millions of endpoints (clients). I will focus on two fundamental challenges unique to applying datadriven approaches in networking: the need for expressive models to capture complex factors affecting QoE, and the need for scalable platforms to make real-time decisions with fresh data from geo-distributed clients. Our solutions address these challenges in practice by integrating several domain-specific insights in networked applications with machine learning algorithms and systems, and achieve better QoE than using many standard machine learning solutions. I will present end-to-end systems that yield substantial QoE improvement and higher user engagement for video streaming and VoIP. Two of my projects, CFA and VIA, have been used in industry by Conviva and Skype, companies that specialize in QoE optimization for video streaming and VoIP, respectively.
Risk of breast cancer in female survivors of childhood Hodgkin's disease in Britain: A population‐based study

There is now widespread evidence that female survivors of Hodgkin's disease who have been treated with supradiaphragmatic radiotherapy are at an increased risk of breast cancer. Mantle irradiation, which includes irradiation of the mediastinum, conveys a particularly high risk. Previously published studies have found a wide variation in risk. To provide British estimates of risk to inform surveillance programmes, we carried out the first British population‐based cohort study of breast cancer in female survivors of childhood Hodgkin's disease. From the underlying cohort of the British Childhood Cancer Survivor Study, a cohort of 18,123 British 5‐year survivors of childhood cancer diagnosed between 1940 and 1991, there were in total 383 female 5‐year survivors of childhood Hodgkin's disease. Sixteen of these 383 survivors went on to develop invasive breast cancer subsequent to 5‐year survival (standardised incidence ratio, 11.5; 95% confidence interval (95% CI), 6.6–18.6) and all of these 16 survivors had been treated with supradiaphragmatic irradiation as treatment for childhood Hodgkin's disease. The cumulative risk of breast cancer by 25 years of follow up was 9.9% (95% CI, 3.3–16.6) for all patients and 12.2% (95% CI, 4.3–20.1) for those treated with supradiaphragmatic radiotherapy. The cumulative risk of breast cancer in female survivors of childhood Hodgkin's disease in Britain is at the lower end of previous estimates. We hope that our data may provide a basis for future surveillance and for counselling survivors as to their likely risk of breast cancer. © 2006 Wiley‐Liss, Inc.
LPV system analysis via quadratic separator for uncertain implicit systems

This paper considers a class of linear systems containing time-varying parameters whose behavior is not known exactly. We assume that the parameters vary within known intervals and there are known bounds on their rates of variation. We give a computationally verifiable condition for stability of the system for all possible parameter variations. In particular, we first show that the information on the rate bounds can be exploited by considering an augmented system described by an implicit model. Through the analysis of the implicit system using the quadratic separator, we obtain a sufficient stability condition for the original system. Moreover, we show that the condition thus obtained is equivalent to the existence of a Lyapunov function that depends on the parameters in a linear fractional manner. Finally, the computational aspects of the proposed stability conditions are addressed in terms of linear matrix inequalities which can be solved efficiently via interior point methods.
A connection between chaotic and conventional cryptography

Many encryption methods involving chaotic dynamics have been proposed in the literature since the 1990's. Most of them consist of ldquomixingrdquo the confidential information being transmitted through an insecure channel, with a chaotic analog or digital sequence. The recovering of the original information usually calls for reproducing, at the receiver side, the same chaotic signal as at the transmitter side. The synchronization mechanism of the two chaotic signals is known as chaos synchronization. In this paper, a connection between chaotic and conventional encryption is established with special emphasis on two of the most attractive schemes, namely, message embedding and hybrid message embedding. The main point can be stated as follows: the (hybrid) message-embedded cryptosystem is equivalent to a conventional self-synchronizing stream cipher under flatness conditions.
Cardiovascular risk factors in middle-aged men in 24 towns.

this gives a clue about why some serotypes are more pathogenic than others. The sporadic outbreaks of disease are described in the article as something of a mystery. However, there are three possible sources. Firstly, air travel allows the rapid transport of the natives of an endemic area, who may bring with them a mild eye or pharyngeal infection, and of Westerners who become infected in an endemic area and return before the onset of symptoms (incubation lasts up to 14 days). Secondly, infection may persist as chronic conjunctivitis.6 Thirdly, an extraocular site could be the source of virus causing eye disease. Group II adenoviruses have been isolated from the genital tract of asymptomatic women.1 7These adenoviruses could join the TRIC (trachoma inclusion conjunctivitis) agent as a cause of an oculogenital syndrome. In the case of the TRIC agent very occasional eye infection appears to be the result of a common genitourinary infection,8 whereas occasional infection of the genitourinary tract by adenovirus could be the source of outbreaks of eye disease. A B TULLO
Extending a local matching face recognition approach to low-resolution video

Identifying persons in surveillance videos by automatic face recognition is a difficult task, caused by poor image resolution among other things. For high-resolution face data, local matching approaches have proven to achieve better results than holistic ones. However, for low-resolution videos, the holistic approaches are the most widely used solution because the scale can be changed easily. Whereas, the local matching approaches are not commonly used as the decreasing size of the local regions raises difficulties. With local binary patterns (LBP) as feature for local matching, we address this problem by suggesting several modifications. By using different scales and temporal fusion, we can avoid sparse LBP-histograms in the small local regions even for low resolutions. Following this concept, the application range of the local matching approach is extended down to faces with a size of 8 × 8 pixels. Reaching this scale enables face recognition in low-resolution surveillance videos.
Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance

Skin dendritic cells (DCs) control the immunogenicity of cutaneously administered vaccines. Antigens targeted to DCs via the C‐type lectin Langerin/CD207 are cross‐presented to CD8+ T cells in vivo. We investigated the relative roles of Langerhans cells (LCs) and Langerin+ dermal DCs (dDCs) in different vaccination settings. Poly(I:C) and anti‐CD40 agonist antibody promoted cytotoxic responses upon intradermal immunization with ovalbumin (OVA)‐coupled anti‐Langerin antibodies (Langerin/OVA). This correlated with CD70 upregulation in Langerin+ dDCs, but not LCs. In chimeric mice where Langerin targeting was restricted to dDCs, CD8+ T‐cell memory was enhanced. Conversely, providing Langerin/OVA exclusively to LCs failed to prime cytotoxicity, despite initial antigen cross‐presentation to CD8+ T cells. Langerin/OVA combined with imiquimod could not prime CD8+ T cells and resulted in poor cytotoxicity in subsequent responses. This tolerance induction required targeting and maturation of LCs. Altogether, Langerin+ dDCs prime long‐lasting cytotoxic responses, while cross‐presentation by LCs negatively influences CD8+ T‐cell priming. Moreover, this highlights that DCs exposed to TLR agonists can still induce tolerance and supports the existence of qualitatively different DC maturation programs.
Separate and combined effects of gabapentin and [INCREMENT]9-tetrahydrocannabinol in humans discriminating [INCREMENT]9-tetrahydrocannabinol

The aim of the present study was to examine a potential mechanism of action of gabapentin to manage cannabis-use disorders by determining the interoceptive effects of gabapentin in cannabis users discriminating [INCREMENT]9-tetrahydrocannabinol ([INCREMENT]9-THC) using a pharmacologically selective drug-discrimination procedure. Eight cannabis users learned to discriminate 30 mg oral [INCREMENT]9-THC from placebo and then received gabapentin (600 and 1200 mg), [INCREMENT]9-THC (5, 15, and 30 mg), and placebo alone and in combination. Self-report, task performance, and physiological measures were also collected. [INCREMENT]9-THC served as a discriminative stimulus, produced positive subjective effects, elevated heart rate, and impaired psychomotor performance. Both doses of gabapentin substituted for the [INCREMENT]9-THC discriminative stimulus and engendered subjective and performance-impairing effects that overlapped with those of [INCREMENT]9-THC when administered alone. When administered concurrently, gabapentin shifted the discriminative-stimulus effects of [INCREMENT]9-THC leftward/upward, and combinations of [INCREMENT]9-THC and gabapentin generally produced larger effects on cannabinoid-sensitive outcomes relative to [INCREMENT]9-THC alone. These results suggest that one mechanism by which gabapentin might facilitate cannabis abstinence is by producing effects that overlap with those of cannabinoids.
mCell: platform independent communication for small groups

In this paper, we describe the development and experiences with a mobile group communication application, mCell, that runs on a mobile phone. We present the underlying design implications, the application implementation, and a user study, where three groups used the application for one month. The findings of the user study reveal general user experiences with the application and show different patterns of usage depending on the social setting of the group, and how the preferred features vary accordingly.