Miracle-dz/UniFAR-FTUs huggingface dataset:
SNDlib 1.0—Survivable Network Design Library

This article describes the Survivable Network Design Library (SNDlib), a data library for fixed telecommunication network design available at http://sndlib.zib. de. In the current version 1.0, the library contains data related to 22 networks which, combined with a set of selected planning parameters, leads to 830 network design problem instances. In this article, we discuss the data concepts of SNDlib and describe a mathematical model for each design problem considered in the library. We also provide information on characteristic features and the origin of the SNDlib problem instances. © 2009 Wiley Periodicals, Inc. NETWORKS, 2010
Diversify to Survive: Making Passwords Stronger with Adaptive Policies

Password-composition policies are intended to increase resistance to guessing attacks by requiring certain features (e.g., a minimum length and the inclusion of a digit). Sadly, they often result in users' passwords exhibiting new, yet still predictable, patterns. In this paper, we investigate the usability and security of adaptive password-composition policies, which dynamically change password requirements over time as users create new passwords. We conduct a 2,619- participant between-subjects online experiment to evaluate the strength and usability of passwords created with two adaptive password policies. We also design and test a feedback system that guides users to successfully create a password conforming to these policies. We find that a well-configured, structure-based adaptive password policy can significantly increase password strength with little to no decrease in usability. We discuss how system administrators can use these results to improve password diversity.
Optimal time-consistent monetary and fiscal policy under sticky prices

This paper studies optimal monetary and fiscal policy in a stochastic economy with sticky prices and monopolistic competition on its product markets. Our main objective is to characterize optimal time-consistent (Markov) policies and to compare their characteristics to the ones implemented by a Ramsey policy maker. We perform this comparison within the framework of a stochastic production economy where the real value of the government’s net wealth/indebtedness is an endogenous state variable. Our main findings are the following: (i) the dynamic properties of the Ramsey allocation depend on the relevant steady state; (ii) at the steady state endogenously selected by the Markovian policy maker, the dynamic properties of the Ramsey and the Markov allocation dier in
THE GENERALIZED UNCERTAINTY PRINCIPLE AND CORRECTIONS TO THE CARDY–VERLINDE FORMULA IN SAdS5 BLACK HOLES

In this paper, we investigate a possible modification to the temperature and entropy of five-dimensional Schwarzschild anti-de Sitter black holes due to the incorporation of stringy corrections to the modified uncertainty principle. Then, we subsequently argue for corrections to the Cardy–Verlinde formula in order to account for the corrected entropy. Then, we show that one can taking into account the generalized uncertainty principle corrections of the Cardy–Verlinde entropy formula by just redefining the Virasoro operator L0 and the central charge c.
Network Coding-based AOMDV routing in MANET

A Mobile Ad Hoc Network (MANET) is a dynamic wireless network that can be formed without the need for any pre-existing infrastructure in which each node can act as a router. Due to bandwidth constraint and dynamic topology of mobile ad hoc networks, multipath supported routing is a very important research issue. This paper proposes a Network Coding-based AOMDV routing algorithm in MANET (NC-AOMDV). It is typically proposed in order to increase the reliability of data transmission or to provide load balancing. In our simulation, we compare NC-AOMDV routing protocol with AODVM routing protocol, in terms of the packet delivery ratio, packet overhead, and average end-to-end delay when a packet is transmitted. The simulation results show that the NC-AOMDV routing protocol provide an accurate and efficient method of estimating and evaluating the route stability in dynamic MANETs.
"Sorry, I Forgot the Attachment": Email Attachment Prediction

The missing attachment problem: a missing attachment generates a wave of emails from the recipients notifying the sender of the error. We present an attachment prediction system to reduce the volume of missing attachment mail. Our classifier could prompt an alert when an outgoing email is missing an attachment. Additionally, the system could activate an attachment recommendation system, whereby suggested documents are oered once the system determines the user is likely to include an attachment, eectively reminding the user to include the attachment. We present promising initial results and discuss implications of our work.
A topology‐based scaling mechanism for Apache Storm

As more and more well‐known companies, such as Twitter, Yahoo, and Alibaba, start to focus on real‐time big data applications, how to build a platform for processing real‐time data becomes an important issue. Among all the real‐time processing systems, Apache Storm is the most well‐known and representative open‐source, distributed, real‐time computation system. In Storm, the computation is implemented by a topology such as a graph where nodes are operators and edges represent the data flows between operators. In big data processing and analysis systems, scalability is an important issue. Storm provides rebalance mechanism for its scalability property, which can adjust the parallelism of a running topology. However, there are some drawbacks in rebalance command, such as resource usage restriction and topology execution suspension. In this paper, we propose a topology‐based scaling mechanism for Apache Storm. When a topology is overloaded, it scales by adjusting the number of the cloned topologies or replaced by another new topology with more tasks. When scaling by topology‐based mechanism, it eliminates resource usage restriction and execution suspension in the topology, and the procedure is automatically launched. The experimental results show that our topology‐based scaling mechanism can improve the scaling performance of Storm. Copyright © 2016 John Wiley & Sons, Ltd.
Synaptic and intrinsic responses of medical entorhinal cortical cells in normal and magnesium-free medium in vitro.

1. Extracellular recordings were made from slices of hippocampus plus parahippocampal regions maintained in vitro. Field potentials, recorded in the entorhinal cortex after stimulation in the subiculum, resembled those observed in vivo. 2. Washout of magnesium from the slices resulted in paroxysmal events which resembled those occurring during sustained seizures in vivo. These events were greatest in amplitude and duration in layers IV/V of the medial entorhinal cortex and could occur both spontaneously and in response to subicular stimulation. Spontaneous seizure-like events were not prevented by severing the connections between the hippocampus and entorhinal cortex, but much smaller and shorter events occurring in the dentate gyrus were stopped by this manipulation. Both spontaneous and evoked paroxysmal events were blocked by perfusion with the N-methyl-D-aspartate (NMDA) receptor antagonist, DL-2-amino-5-phosphonovalerate (2-AP5). 3. Neurons in layers IV/V were characterized by intracellular recording. Injection of depolarizing current in most cells evoked a train of nondecrementing action potentials with only weak spike frequency accommodation and little or no posttrain after hyperpolarization. 4. A small number of cells displayed burst response when depolarized by positive current. The burst consisted of a slow depolarization with superimposed action potentials which decreased in amplitude and increased in duration during the discharge. The burst was terminated by a strong after hyperpolarization and thereafter, during prolonged current pulses a train of nondecrementing spikes occurred. The burst response remained if the cell was held at hyperpolarized levels but was inactivated by holding the cell at a depolarized level. 5. Depolarizing synaptic potentials could be evoked by stimulation in the subiculum. A delayed and prolonged depolarization clearly decremented with membrane hyperpolarization and, occasionally, increased with depolarization. 6. Washout of magnesium from the slices resulted in an enhancement of the late depolarization and a reversal of its voltage dependence. Eventually a single shock to the subiculum evoked a large all-or-none paroxysmal depolarization associated with a massive increase in membrane conductance. Similar events occurred spontaneously in all cells tested. The paroxysmal depolarizations, both spontaneous and evoked, were rapidly blocked by 2-AP5. 7. It is concluded that medial entorhinal cortical cells possess several intrinsic and synaptic properties which confer an extreme susceptibility to generation of sustained seizure activity. (ABSTRACT TRUNCATED AT 400 WORDS)
> Replace This Line with Your Paper Identification Number (double-click Here to Edit) < 1 a Biomimetic, 4.5µw, 120+db, Log-domain Cochlea Channel with Agc

—This paper deals with the design and performance evaluation of a new analogue CMOS cochlea channel of increased biorealism. The design implements a recently proposed transfer function, namely the One-Zero Gammatone Filter (or OZGF), which provides a robust foundation for modeling a variety of auditory data such as realistic passband asymmetry, linear low-frequency tail and level-dependent gain. Moreover, the OZGF is attractive because it can be implemented efficiently in any technological medium – analogue or digital – using standard building blocks. The channel was synthesized using novel, low-power, Class-AB, log-domain, biquad-ratic filters employing MOS transistors operating in their weak inversion regime. Furthermore, the paper details the design of a new low-power automatic gain control circuit that adapts the gain of the channel according to the input signal strength, thereby extending significantly its input dynamic range. We evaluate the performance of a 4 th-order OZGF channel (equivalent to an 8 th-order cascaded filter structure) through both detailed simulations and measurements from a fabricated chip using the commercially available 0. 35µm AMS CMOS process. The whole system is tuned at 3kHz, dissipates a mere 4. 46µW of static power, accommodates 124dB (at <5% THD) of input dynamic range at the center frequency and is set to provide up to 70dB of amplification for small signals.
Glyphs for software visualization

Producing large software systems is an extremely challenging engineering task. The main reason is the difficulty of managing the enormous amounts of code and the great numbers of people involved in the effort. We have developed three novel interactive glyphs specifically tuned for visualizing software data. Our glyphs enable users to track software errors, isolate problems and monitor development progress. To demonstrate our glyphs' functionality, we apply them to visualizing statistics from a multi-million line software project.
Mechanisms of isometric exercise-induced hypoalgesia in young and older adults

MECHANISMS OF ISOMETRIC EXERCISE-INDUCED HYPOALGESIA IN YOUNG AND OLDER ADULTS Kathy J. Lemley Marquette University, 2014 Pain reduction following exercise (exercise-induced hypoalgesia; EIH) is wellestablished in young adults. Specific to isometric exercise, the greatest EIH follows low intensity contractions held for long duration. The EIH response of older adults is not known; and the mechanisms for EIH are unclear at any age. This dissertation aimed to address these unknowns through a series of three studies. In study one, repeatability of pressure pain reports (pain threshold and pain ratings) was assessed in healthy older adults, including the impact of psychological factors. Pain reports, measured before and after quiet rest, did not change following quiet rest. Higher state anxiety was associated with greater pain. Study two examined the impact of isometric contractions that varied in intensity and duration on pain relief in healthy older adults. Pressure pain was assessed before and after isometric contractions of the left elbow flexor muscles. Unlike young adults, older adults experienced EIH similarly across different isometric exercise tasks and women experienced greater pain reduction than men. Anxiety did not influence EIH. Conditioned pain modulation (CPM; a reduction in pain to a test stimulus in the presence of a noxious conditioning stimulus) has been hypothesized to augment EIH when exercise is painful. In study three, CPM and EIH were assessed in healthy young and older adults. CPM was measured as the difference in pressure pain with the foot immersed in neutral-temperature water versus noxious ice water. While young adults experienced CPM, older adults experienced a range of responses from hypoalgesia to hyperalgesia with foot immersion in the ice water bath. CPM predicted EIH and was associated with state anxiety; however state anxiety was unrelated to EIH. Results for age and sex-related differences in pain perception varied across studies or sessions. The results of this dissertation suggest anxiety influences pain sensitivity, but not magnitude of EIH. Older adults, particularly women, experience reductions in pain following isometric exercise and are less dependent upon task than young adults. CPM may predict EIH response following isometric exercise in both young and older adults and may be a useful tool in clinical decision making for adults experiencing pain.
Article De-duplication Using Distributed Representations

In news recommendation systems, eliminating redundant information is important as well as providing interesting articles for users. We propose a method that quantifies the similarity of articles based on their distributed representation, learned with the category information as weak supervision. This method is useful for evaluation under tight time constraints, since it only requires low-dimensional inner product calculation for estimating similarities. The experimental results from human evaluation and online performance in A/B testing suggest the effectiveness of our proposed method, especially for quantifying middle-level similarities. Currently, this method is used on Yahoo! \ JAPAN's front page, which has millions of users per day and billions of page views per month.
A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture

Clustered regularly interspaced short palindromic repeat (CRISPR) RNA-guided nucleases have gathered considerable excitement as a tool for genome engineering. However, questions remain about the specificity of their target site recognition. Most previous studies have examined predicted off-target binding sites that differ from the perfect target site by one to four mismatches, which represent only a subset of genomic regions. Here, we use ChIP-seq to examine genome-wide CRISPR binding specificity at gRNA-specific and gRNA-independent sites. For two guide RNAs targeting the murine Snurf gene promoter, we observed very high binding specificity at the intended target site while off-target binding was observed at 2- to 6-fold lower intensities. We also identified significant gRNA-independent off-target binding. Interestingly, we found that these regions are highly enriched in the PAM site, a sequence required for target site recognition by CRISPR. To determine the relationship between Cas9 binding and endonuclease activity, we used targeted sequence capture as a high-throughput approach to survey a large number of the potential off-target sites identified by ChIP-seq or computational prediction. A high frequency of indels was observed at both target sites and one off-target site, while no cleavage activity could be detected at other ChIP-bound regions. Our data is consistent with recent finding that most interactions between the CRISPR nuclease complex and genomic PAM sites are transient and do not lead to DNA cleavage. The interactions are stabilized by gRNAs with good matches to the target sequence adjacent to the PAM site, resulting in target cleavage activity.
Integration approach of mechatronics system in PLM systems

The design of mechatronic systems requires the integration of data concerning numerous disciplines (mechanical, electric CAD, automatism, embarked software.). In this context, the PLM (Product Lifecycle Management) systems define a naturally relevant solution to manage those data. However, being built around the CAD, the structure of these systems does not allow a real integration in terms of re-use, reconfiguration or calculation of impact. This article proposes a frame of definition for the global integration of components into an application library (CAD, Automatic, HMI.) within a PLM including the mechatronic systems. This integration approach is based on the construction of a meta-model structured with multi-faceted components. The propositions were experimented in the context of a simple mechatronic system and implemented with the PLM Windchill system.
General video game playing escapes the no free lunch theorem

Popular topics in current research within the games community are general game playing and general video game playing. Both of these efforts seek to find relatively general purpose AI to play games. Within the optimization community we are approaching the 20th anniversary of the no free lunch theorem. In this paper we suggest reasons why a games version of a no free lunch result is probably not problematic. This is accomplished by noting that none of the "general" efforts are - or should be - actually general. Technology is proposed to exploit the lack of generality to permit more effective game playing AIs to be designed. A program for classifying games is outlined that consists of gathering performance data on many games for many algorithms and then using the resulting matrix of performance data to create a tree structured classification of the games. This classification is proposed as the basis for assigning games to appropriate algorithms within a more general framework. A novel algorithm that yields more stable tree-based classification is also proposed.
Metabolic Syndrome in Adolescents With Spinal Cord Dysfunction

Abstract Objective: The purpose of this study was to determine the prevalence of components of the metabolic syndrome in adolescents with spinal cord injury (SCI) and spina bifida (SB), and their associations with obesity in subjects with and without SCI and SB. Methods: Fifty-four subjects (20 SCI and 34 SB) age 11 to 20 years with mobility impairments from lower extremity paraparesis were recruited from a hospital-based clinic. Sixty able-bodied subjects who were oversampled for obesity served as controls (CTRL). Subjects were categorized as obese if their percent trunk fat measured by dual x-ray absorptiometry (DXA) was>30.0> for males and>35 . 0> for females. Ten SCI, 24 SB, and 19 CTRL subjects were classified as obese. Fasting serum samples were collected to determine serum glucose, insulin, and lipid concentrations. Metabolic syndrome was defined as having #x003D;3 of the following components: (a) obesity; (b) high-density lipoprotein (HDL) <45 mg/dl for males;<50 mg/dl for females; (c) triglycerides #x003D;100 mg/dl; (d) systolic or diastolic blood pressure95th percentile for age/ height/gender, and (e) insulin resistance determined by either fasting serum glucose 100-125 mg/dl; fasting insulin #x003D;20 μU /ml; or homeostasis model assessment of insulin resistance #x003D;4.0 . Results: Metabolic syndrome was identified in 32.4>of the SB group and 55> of the SCI group. Metabolic syndrome occurred at a significantly higher frequency in obese subjects (SB = 45 .8>, SCI = 100>, CTRL = 63.2>) than nonobese subjects (SB = 0>, SCI = 10>, CTRL = 2.4>). Conclusions: The prevalence of metabolic syndrome in adolescents with SB/ SCI is quite high, particularly in obese individuals. These findings have important implications due to the known risks of cardiovascular diseases and diabetes mellitus associated with metabolic syndrome in adults, particularly those with spinal cord dysfunction.
The contribution of the Patient Support Assistant to direct patient care: An exploration of nursing and PSA role perceptions

Health care systems have seen the introduction of the unregulated worker into patient care areas to assist Registered Nurses (RNs) in the provision of health care. A study was undertaken to identify the perceptions of both nurses and unregulated workers of the unregulated worker role in direct patient care in a regional hospital in New South Wales, Australia. The nomenclature used for a non regulated worker in the workplace in which this study occurred is Patient Support Assistant (PSA). Separate surveys were designed for PSA and nursing staff. Twenty seven per cent of PSAs (n=21) and 36% of nursing staff surveyed (n=120) responded. Results identified that both groups identified the main role of PSAs were attending to general cleaning and providing physical assistance to nurses, medical and physiotherapy staff, primarily for manual handling of heavy or difficult patients. Some activities of the role identified in the job description, such as pre-operative shaves on male patients and assisting with the application of traction, appeared no longer to be relevant for current practices. Both groups identified a positive team working relationship between nurses and PSAs. However, there was evidence to suggest that not all RNs had a clear understanding of the role of the PSA and the PSAs believed that they did not receive adequate feedback about their work. There was a mixed view as to whom the PSA should report. A high percentage of RNs felt they should be responsible for the supervision of the PSA. This was in contrast to a high percentage also believing that RNs should not be accountable either for PSA work or for delegating tasks to PSAs. Challenges voiced by PSAs included being expected to achieve both allocated cleaning tasks and provide patient support, being requested to assist with aggressive patients and working with other PSAs. A major recommendation of the study is that employment of Assistants in Nursing may provide enhanced scope and role clarity for unregulated workers to assist nurses in providing nursing care.
A Fresh Look at Multicanonical Monte Carlo from a Telecom Perspective

The Multicanonical Monte Carlo (MMC) technique is a new form of adaptive importance sampling (IS). Thanks to its blind adaptation algorithm, it does not require an in-depth system knowledge for exploitation as does traditional IS. Hence MMC is a practical, handy tool to estimate via simulation the probability of rare events in complex telecom systems, such as the symbol error rate or the outage probability. In this paper, we present the analytical connections between MMC and IS, and describe the recursive algorithm via which MMC seeks an optimal "flat-histogram" warping. We also provide practical guidelines on how MMC can be successfully applied in telecom to achieve accelerations of simulation time by many orders of magnitude with respect to standard Monte Carlo.