Miracle-dz/UniFAR-FTUs huggingface dataset:
Design of controlling home appliance remotely using raspberry pi

Controlling home appliances by controlling electrical or electronic appliances remotely, things can be done automatically in the desired environment. Very first few implementations of Automation included simple security systems like alarms, but today automation can be applied in every system of gadgets. Using Home automation can make you do some very important things very easily and with higher controllability. Other than combining sensors and code to make things work automatically, Home automation can also be applied as an implementation of remote computing by giving remote access of the system to the user so that the user can monitor and control the system according to the need. In this project we have automated a 220v supply which can have the load of a bulb or any electrical device, we have used a temperature sensor to monitor the room temperature and the temperature can be seen on the web interface on any mobile device and we have also automated a small 5v D.C supply which can be used to attach a motor or can have various applications like controlling the latch of a door or it can be made to work sporadically by integrating it with sensors and readings. In this papera web interface has been developed using raspberry pi as a web server for operating the home electronic/electrical appliances through any Wi-Fi capable mobile device.
Vezf1/DB1 Is an Endothelial Cell-specific Transcription Factor That Regulates Expression of the Endothelin-1 Promoter*

Coordinated gene regulation within the vascular endothelium is required for normal cardiovascular patterning during development and for vascular homeostasis during adulthood, yet little is known about the mechanisms that regulate endothelial transcriptional events. Vascular endothelial zinc finger 1 (Vezf1)/DB1 is a recently identified zinc finger-containing protein that is expressed specifically within endothelial cells during development. In this report, we demonstrate that Vezf1/DB1 is a nuclear localizing protein that potently and specifically activates transcription mediated by the human endothelin-1 promoter, in a Tax-independent manner, in transient transfection assays. Using a combination of deletion mutagenesis and electrophoretic mobility shift assays, a novel Vezf1/DB1-responsive element was localized to a 6-base pair (bp) motif, ACCCCC, located 47 bp upstream of the endothelin-1 transcription start site. Recombinant Vezf1/DB1 also bound to this sequence, and a 2-bp mutation in this element abolished Vezf1/DB1 responsiveness by the endothelin-1 promoter. Vezf1/DB1 could be identified with a specific antibody in nuclear complexes from endothelial cells that bound to this element. Regulation of endothelin-1 promoter activity by Vezf1/DB1 provides a mechanism for endothelin-1 expression in the vascular endothelium during development and to maintain vascular tone; Vezf1/DB1 itself is a candidate transcription factor for modifying endothelial cell phenotypes in order to appropriately assemble and maintain the cardiovascular system.
Habitual intake of dietary flavonoids and risk of Parkinson disease

Objective: To prospectively examine whether higher intakes of total flavonoids and their subclasses (flavanones, anthocyanins, flavan-3-ols, flavonols, flavones, and polymers) were associated with a lower risk of developing Parkinson disease (PD). Methods: In the current analysis, we included 49,281 men in the Health Professional Follow-up Study and 80,336 women from the Nurses' Health Study. Five major sources of flavonoid-rich foods (tea, berry fruits, apples, red wine, and orange/orange juice) were also examined. Flavonoid intake was assessed using an updated food composition database and a validated food frequency questionnaire. Results: We identified 805 participants (438 men and 367 women) who developed PD during 20–22 years of follow-up. In men, after adjusting for multiple confounders, participants in the highest quintile of total flavonoids had a 40%lower PD risk than those in the lowest quintile (hazard ratio [HR] = 0.60; 95% confidence interval 0.43, 0.83; p trend = 0.001). No significant relationship was observed in women (p trend = 0.62) or in pooled analyses (p trend = 0.23). In the pooled analyses for the subclasses, intakes of anthocyanins and a rich dietary source, berries, were significantly associated with a lower PD risk (HR comparing 2 extreme intake quintiles were 0.76 for anthocyanins and 0.77 for berries, respectively; p trend < 0.02 for both). Conclusions: Our findings suggest that intake of some flavonoids may reduce PD risk, particularly in men, but a protective effect of other constituents of plant foods cannot be excluded.
Protective Role of the Virus-Specific Immune Response for Development of Severe Neurologic Signs in Simian Immunodeficiency Virus-Infected Macaques

ABSTRACT The pathogenesis of human immunodeficiency virus-associated motor and cognitive disorders is poorly understood. In this context both a protective and a harmful role of the immune system has been discussed. This question was addressed in the present study by correlating the occurrence of neurologic disease in simian immunodeficiency virus (SIV)-infected macaques with disease progression and the humoral and cellular intrathecal antiviral immune response. Overt neurologic signs consisting of ataxia and apathy were observed at a much higher frequency in rapid progressor animals (6 of 12) than in slow progressors (1 of 7). Whereas slow progressors mounted a strong antiviral antibody (Ab) response as evidenced by enzyme-linked immunosorbent and immunospot assays, neither virus-specific Ab titers nor Ab-secreting cells could be found in the cerebrospinal fluid (CSF) or brain parenchyma of rapid progressors. Similarly, increased infiltration of CD8+ T cells and cytotoxic T lymphocytes specific for viral antigens were detected only in the CSF of slow progressors. The finding that neurologic signs develop frequently in SIV-infected macaques in the absence of an antiviral immune response demonstrates that the immune system does not contribute to the development of motor disorders in these animals. Moreover, the lower incidence of neurologic symptoms in slow progressors with a strong intrathecal immune response suggests a protective role of the virus-specific immunity in immunodeficiency virus-induced central nervous system disease.
An intelligent agent for fault reconnaissance in sensor networks

An embedded sensor network is a system of nodes, each of which is equipped with a certain amount of sensing, actuating, computation, communication and storage components. Two major components of sensor nodes are sensing unit and wireless transceiver. They directly interact with nodes in wireless sensor networks (WSNs) that are easily prone to failure due to hardware failure, communication link errors, energy depletion, malicious attacks, etc. Even if the sensor node hardware is in excellent condition, still the communication between sensor nodes depends on many factors such as signal strength, obstacles and interference. Degradation in these factors results in low reliability of sensor nodes. One of the key prerequisite for an effective, efficient embedded sensor network is utilization of low-cost, low-overhead and high-resilient fault-inference techniques. Our attempt is to address fault-inference issues in sensor networks using an agent-based approach. Our proposed approach involves an intelligent agent that outfitted with a fault-inference engine. This engine profits from Expectation Maximization (EM) algorithm to evaluate fault probabilities of sensor nodes. Our experiment in a wireless sensor testbed is conducted to demonstrate the correctness and effectiveness of our approach.
Comparison Of Immunomodulator mRNA and Protein Expression in the Lungs of Stachybotrys chartarum Spore-Exposed Mice

Stachybotrys chartarum is an important toxigenic fungus that has been associated with respiratory disease onset in animals and humans. It can be separated into macrocyclic trichothecene-producing and nonproducing chemotypes based on secondary metabolite production. However, effects of spores of the two chemotypes on lung inflammatory responses are poorly understood. In this study, real-time reverse-transcription polymerase chain reaction (RT-PCR) and enzyme linked immunosorbent assay (ELISA) were used to investigate time-course (1, 3, 6, 24, and 48 h postinstillation [PI]) relationships in mice intratracheally exposed to 300 spores/g body weight of a macrocyclic trichothecene-producing (JS 58-17) and a nonproducing (JS 58-06) S. chartarum isolate and of Cladosporium cladosporioides. There were marked differences in the magnitude and temporal patterns of mouse lung immune responses to intratracheal exposure to spores of these species at this spore dose. Both macrophage inflammatory protein 2 (MIP-2) and surfactant protein-D (SP-D) mRNA expression were significantly upregulated in lungs of JS 58-17-treated animals compared to that of all other treatment animals at 6 and 24 h PI. Heightened mRNA expression of these immunomodulators combined with comparatively depressed MIP-2 and tumor necrosis factor (TNF)-α protein expression suggests that the action of macrocyclic trichothecenes sequestered in 58-17 spores is involved. Interestingly, TNF-α protein expression in all spore treatment animal groups was also significantly increased over that in saline controls. Similarities in expression among all spore treatment animals suggest that chemicals other than toxic secondary metabolites, and possibly spore-sequestered 1,3-β-D-glucan, may contribute to lung pathogenesis.
Global Transcriptional Analysis of Dehydrated Salmonella enterica Serovar Typhimurium

ABSTRACT Despite the scientific and industrial importance of desiccation tolerance in Salmonella, knowledge regarding its genetic basis is still scarce. In the present study, we performed a transcriptomic analysis of dehydrated and water-suspended Salmonella enterica serovar Typhimurium using microarrays. Dehydration induced expression of 90 genes and downregulated that of 7 genes. Ribosomal structural genes represented the most abundant functional group with a relatively higher transcription during dehydration. Other main induced functional groups included genes involved in amino acid metabolism, energy production, ion transport, transcription, and stress response. The highest induction was observed in the kdpFABC operon, encoding a potassium transport channel. Knockout mutations were generated in nine upregulated genes. Five mutants displayed lower tolerance to desiccation, implying the involvement of the corresponding genes in the adaptation of Salmonella to desiccation. These included genes encoding the isocitrate-lyase AceA, the lipid A biosynthesis palmitoleoyl-acyltransferase Ddg, the modular iron-sulfur cluster scaffolding protein NifU, the global regulator Fnr, and the alternative sigma factor RpoE. Notably, these proteins were previously implicated in the response of Salmonella to oxidative stress, heat shock, and cold shock. A strain with a mutation in the structural gene kdpA had a tolerance to dehydration comparable to that of the parent strain, implying that potassium transport through this system is dispensable for early adaptation to the dry environment. Nevertheless, this mutant was significantly impaired in long-term persistence during cold storage. Our findings indicate the involvement of a relatively small fraction of the Salmonella genome in transcriptional adjustment from water to dehydration, with a high prevalence of genes belonging to the protein biosynthesis machinery.
A Comparison between Image Metadata and Visual Features to Classify Social Media Images

Image classification is needed to build image search and recommender systems. This paper applies classification techniques on two properties of the social media images: metadata of the images and their pixel intensities. Naive Bayes is applied on the tags and captions extracted from the images while a Convolutional Neural Network is trained for classifying images based on pixel values. Our dataset consists of more than 33,000 Flickr images segregated into 18 classes. Naive Bayes is applied by converting the metadata into a feature vectors. The Convolutional Neural Network is made up of three convolutional layers and three fully connected layers. On comparison, it was observed that analyzing the metadata associated with an image rather than the intensities provided better classification.
Toward an Entrepreneurial Public Sector

An entrepreneurial public agency pursues the implementation of innovative programs that may broaden public service choices, increase service quality, and more effectively serve citizens. Such public entrepreneurship depends on risk taking and risk tolerance; however, public servants tend to be generally risk averse in their behaviors and personal preferences, and are therefore less likely to pursue entrepreneurial approaches to public problems. Using social exchange theory as a framework to understand the reciprocal relationship between agency and employee, this study examines whether agency behaviors might alter the risk aversion of those employees and make the agency environment more conducive to entrepreneurship. Findings suggest that managers’ demonstration of risk tolerance, reward for creativity and innovation, and agency solicitation of employee input are positively related to employee perceptions of higher risk tolerance among their peers.
Design of a 4KW interior permanent magnet machine suitable for low speed application

This paper presents a systematic design process for an interior permanent magnet machines (IPMM) containing distributed and concentrated windings in the stator and flat shaped and a v-shaped magnets in the rotor. The machine was designed with large pole numbers suitable for low speed application such as direct drive wind turbine. The paper also presents a comprehensive comparison of performances between distributed and concentrated windings stator in a low speed IPMM. The various steps taken to minimize the cogging torque and torque ripple in the studied IPMMs are discussed in details.
Use of elephant grass (Pennisetum purpureum) acid hydrolysate for microbial oil production by Trichosporon cutaneum

ABSTRACT Elephant grass (Pennisetum purpureum) dilute acid hydrolysate contains 34.6 g/L total sugars. The potential of lipid production by oleaginous yeast Trichosporon cutaneum grown on elephant grass acid hydrolysate was investigated for the first time. During the fermentation process on the elephant grass acid hydrolysate, glucose, xylose, and arabinose could be well utilized as carbon sources by T. cutaneum. Interestingly, xylose was almost no use before glucose was consumed completely. This illustrated that simultaneous saccharification of xylose and glucose by T. cutaneum did not occur on elephant grass acid hydrolysate. The highest biomass, lipid content, lipid yield, and lipid coefficient of T. cutaneum were measured after the sixth day of fermentation and were 22.76 g/L, 24.0%, 5.46 g/L, and 16.1%, respectively. Therefore, elephant grass is a promising raw material for microbial oil production by T. cutaneum.
Clinically relevant QTc prolongation due to overridden drug-drug interaction alerts: a retrospective cohort study.

AIMS To investigate whether, in patients in whom drug-drug interaction (DDI) alerts on QTc prolongation were overridden, the physician had requested an electrocardiogram (ECG), and if these ECGs showed clinically relevant QTc prolongation. METHODS For all patients with overridden DDI alerts on QTc prolongation during 6 months, data on risk factors for QT prolongation, drug class and ECGs were collected from the medical record. Patients with ventricular pacemakers, patients treated on an outpatient basis, and patients using the low-risk combination of cotrimoxazole and tacrolimus were excluded. The magnitude of the effect on the QTc interval was calculated if ECGs before and after overriding were available. Changes of the QTc interval in these cases were compared with those of a control group using one QTc-prolonging drug. RESULTS In 33% of all patients with overridden QTc alerts an ECG was recorded within 1 month. ECGs were more often recorded in patients with more risk factors for QTc prolongation and with more QTc overrides. ECGs before and after the QTc override were available in 29% of patients. Thirty-one percent of patients in this group showed clinically relevant QTc prolongation with increased risk of torsades de pointes or ventricular arrhythmias. The average change in QTc interval was +31 ms for cases and -4 ms for controls. CONCLUSIONS Overriding the high-level DDI alerts on QTc prolongation rarely resulted in the preferred approach to subsequently record an ECG. If ECGs were recorded before and after QTc overrides, clinically relevant QTc prolongation was found in one-third of cases. ECG recording after overriding QTc alerts should be encouraged to prevent adverse events.
Ranking Tag Pairs for Music Recommendation Using Acoustic Similarity

The need for the recognition of music emotion has become apparent in many music information retrieval applications. In addition to the large pool of techniques that have already been developed in machine learning and data mining, various emerging applications have led to a wealth of newly proposed techniques. In the music information retrieval community, many studies and applications have concentrated on tag-based music recommendation. The limitation of music emotion tags is the ambiguity caused by a single music tag covering too many subcategories. To overcome this, multiple tags can be used simultaneously to specify music clips more precisely. In this paper, we propose a novel technique to rank the proper tag combinations based on the acoustic similarity of music clips.
Microneedling Prior to Levulan PDT for the Treatment of Actinic Keratoses: A Split-Face, Blinded Trial.

INTRODUCTION Photodynamic Therapy (PDT) with topical Levulan is an approved and efficacious method for treating actinic keratoses. This therapy depends on the ability of the Levulan (delta amino levulinic acid) to penetrate the stratum corneum and enter the cells of the epidermis. Microneedling is an increasing popular cosmetic therapy in which an array of tiny needles is used to make holes in the epidermis and presumably induce a wound healing cascade that leads to cosmetic improvement of the skin. We were interested to know if prior microneedling would enhance the penetration of topical Levulan and thus enhance the PDT treatment, and if a cosmetic improvement beyond the PDT alone would be seen when it is used in conjunction with microneedling. METHODS 20 patients each with at least 4 non hyperkeratotic AKs on each side of their face were enrolled. All patients were randomized to receive multiple passes with a microneedling device to ½ of their face, left or right, followed by application of Levulan to the entire face. The Levulan was allowed to incubate 1 hour followed by exposure to blue light (Blu U) for 1000 seconds. RESULTS 19 patients completed the study with 4-month follow up. The mean percentage reduction in AKs was 89.3% on the microneedling side versus 69.5% on the PDT alone side, a significant difference. A physician's global cosmetic assessment was performed based on Canfield Visia photographs: 15 of the 19 patients had a noticeable improved cosmetic appearance on one side of the face versus the other, and in 13 of these patients the improved side was the microneedled side. DISCUSSION Prior microneedling significantly enhances the effect of Levulan PDT. It also seems to provide a cosmetic benefit above and beyond the PDT alone. It was safe and well tolerated in this study. J Drugs Dermatol. 2016;15(9):1072-1074.
Did the 1999 NYSE and NASDAQ Listing Standard Changes on Audit Committee Composition Benefit Investors

ABSTRACT: In December 1999, the SEC instituted a new listing standard for NYSE and NASDAQ firms. Listed firms were now required to maintain fully independent audit committees with at least three members. In July 2002, the U.S. Congress legislated these standards through the Sarbanes-Oxley Act. Our research question is whether all investors benefited from the 1999 new rule. Using both an event study and a difference-in-differences methodology, we find no evidence of higher market value or better financial reporting quality resulting from this rule.
Software test estimation tool: Comparable with COCOMOII model

This study illustrates an estimation tool for software test that provides the estimated time and the cost of any sort of software test project. There are different well-recognized estimation tools for software development process [9], however, there remains a lack of standard tools for estimation of Software Test phase. Therefore, the authors developed a web base tool (www.4beats.net/tpet/) in order to determine the time and cost of projects. This paper highlights the comparable result with COCOMOII (Constructive Cost Model) model. More than 22 projects are already estimated by this open tool and from them 5 case projects, namely, Climate Resilient Ecosystems and Livelihood (CREL), Management Accounts Consolidation System for Line Director (LDMACS), PBI (Police Bureau of Investigations) Works Management System Software, PBI Mobile Apps and Human Resources Management System (HRMS) have selected. This paper would play a vital role to estimate time and cost for software test project and be beneficial for the software industry.
Stability and Growth Pact and Fiscal Discipline in the Eurozone

The Economic and Monetary Union in the European Union relies on fiscal coordination among member states to prevent excessive levels of deficit and debt and to ensure the stability of its single currency. This paper examines the framework of fiscal rules put in place before and after the launch of the euro. I find that enforcement of the budgetary limits in the Stability and Growth Pact was insufficient at the institutional level by the European Commission and by the Economic and Financial Affairs Council (ECOFIN), as well as at the level of the financial markets. In order for fiscal rules across the Eurozone to be successful, proposals for reforming the Pact, including the Six-Pack and the Fiscal Compact Treaty, will need to address enforcement problems on both political and market levels.
Neoliberal Policies and Human Trafficking for Labor: Free Markets, Unfree Workers?

While the economic benefits of neoliberalism are widely noted, its impact upon human security is contentious, particularly in the area of equity and economic rights. In this article, we examine the impact of free-market policies upon a particularly egregious abuse of human and labor rights, trafficking in forced and child labor. Drawing from relevant scholarship on market liberalization and human trafficking, we posit that policies that promote market deregulation, reduced state size, and global economic openness are positively related to trafficking of child and forced labor. To test these claims, we combine data on three main facets of pro-market policies—a “business-friendly” regulatory environment, reduced state size, and policies favoring global economic openness—with data on human trafficking for forced and child labor. We find that economic liberalization in general significantly increases the likelihood of human trafficking for labor purposes. Our results further suggest that among the three facets of neoliberal policies, a market-friendly regulatory environment has the most significant impact upon labor trafficking. Overall, our results point to a conflict between the universally professed aversion to human trafficking and the dominant neoliberal approach to economic policy.