Miracle-dz/UniFAR-FTUs huggingface dataset:
Leveraging Information Sharing to Increase Supply Chain Configurability

As supply chains evolve beyond the confines of individual organizations, collaboration has become the Holy Grail in supply chain technology. It plays a key role in achieving flexibility and responsiveness. Information sharing between partners is a key determinant of collaboration. This paper investigates information sharing in four different supply chains—3PL, VMI, CPFR, and supply networks—and compares their information sharing structures, shared data objects, and information flow models. The results show how the various parameters of an information flow model constrain the level of collaboration. Further, the modeling exercise provides insights on how to configure a collaborative supply chain by leveraging information sharing.
Comparisons of typical algorithms in negative sequential pattern mining

Negative sequential pattern (NSP), which contains both non-occurring and occurring items, can play more important roles than positive sequential pattern (PSP) in many applications. NSP mining, however, has been just caught attention and very limited methods are available to mine NSP. Furthermore, there is not a unified definition about negative containment, i.e., how a data sequence contains a negative sequence. So in this paper, we select three typical existing methods, PNSP, Neg-GSP and e-NSP, and compare their definitions, runtime and the number of NSPs. Examples and experiments on same dataset clearly show their differences.
Algorithms to Resolve Conflict in Multiuser Context Aware Ubiquitous Environment

Conflict resolution in context-aware computing is getting more significant attention from researchers as pervasive/ubiquitous computing environments take into account multiple users and multiple applications. In multi-user ubiquitous computing environments, conflicts among user's contexts need to be detected and resolved. Conflicts arise when multiple users try to access or try to have a control on an application. In this paper, the authors propose a series of algorithms to resolve conflict which can be embedded in different context aware applications like context aware devices (say TV, Mobile, AC, and Fan) and Context Aware Ambient (like Meeting Room, Living Room, Restaurant, Coffee Shop, etc.). The algorithms discussed in this paper make use of different tools like Probability, Fuzzy Logic, Bayesian Network and Rough set theory. In addition the algorithms utilize various factors like social, personal and environmental. The motto of this paper is to enable context aware applications to offer socialized and personalized services to multiple users by resolving service conflicts among users.
Phospho-tyrosine dependent protein–protein interaction network

Post‐translational protein modifications, such as tyrosine phosphorylation, regulate protein–protein interactions (PPIs) critical for signal processing and cellular phenotypes. We extended an established yeast two‐hybrid system employing human protein kinases for the analyses of phospho‐tyrosine (pY)‐dependent PPIs in a direct experimental, large‐scale approach. We identified 292 mostly novel pY‐dependent PPIs which showed high specificity with respect to kinases and interacting proteins and validated a large fraction in co‐immunoprecipitation experiments from mammalian cells. About one‐sixth of the interactions are mediated by known linear sequence binding motifs while the majority of pY‐PPIs are mediated by other linear epitopes or governed by alternative recognition modes. Network analysis revealed that pY‐mediated recognition events are tied to a highly connected protein module dedicated to signaling and cell growth pathways related to cancer. Using binding assays, protein complementation and phenotypic readouts to characterize the pY‐dependent interactions of TSPAN2 (tetraspanin 2) and GRB2 or PIK3R3 (p55γ), we exemplarily provide evidence that the two pY‐dependent PPIs dictate cellular cancer phenotypes.
Clinical and psychometric distinction of frontotemporal and Alzheimer dementias.

BACKGROUND A proportion of patients who meet the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Associations criteria for Alzheimer disease (AD) have frontotemporal lobar degeneration (FTLD) confirmed at autopsy, with or without concomitant AD. Thus, the clinical phenotypes of the 2 disorders may overlap. OBJECTIVE To identify clinical and psychometric indicators that distinguish AD from FTLD at initial presentation. DESIGN Longitudinal study of memory and aging. SETTING Alzheimer's Disease Research Center, Washington University School of Medicine. PARTICIPANTS Forty-eight clinically well-characterized cases of autopsy-confirmed FTLD (27 with psychometric testing results) were compared with 27 autopsy-confirmed AD cases. RESULTS Behavioral abnormalities, particularly impulsivity (P<.001), disinhibition (P<.001), social withdrawal (P = .01), and progressive nonfluent aphasia, distinguished individuals with FTLD from those with AD. The individuals with FTLD performed better than those with AD on a visual test of episodic memory (P = .01), but worse on word fluency (P = .02) (performance correlated with aphasic features). Other cognitive and clinical features, including executive dysfunction and memory impairment, were comparable between the FTLD and AD groups. Concomitant histopathological AD was present in 11 of the 48 individuals with FTLD. CONCLUSIONS Clinical and cognitive features of FTLD may overlap with AD, although behavioral and language difficulties distinguish those with FTLD. Memory loss in those with FTLD may in part reflect word-finding difficulties stemming from language dysfunction. Compounding the overlap of FTLD and AD clinical phenotypes is the presence of histopathological AD in almost one fourth of individuals with FTLD.
Generalized and stationary scrolling

We present a generalized definition of scrolling that unifies a wide range of existing interaction techniques, from conventional scrolling through pan and zoom systems and fish-eye views. Furthermore it suggests a useful class of new scrolling techniques in which objects do not move across the display. These “stationary scrolling” techniques do not exhibit either of two problems that plague spatial scrolling system: discontinuity in salience and the undermining of the user's spatial memory.
An Overview of Multipath TCP

TCP has remained mostly unchanged for 20 years, even as its uses and the networks on which it runs have evolved. Multipath TCP is an evolution of TCP that allows it to run over multiple paths transparently to applications. In this article, we explain how Multipath TCP works, and why you should want to start using it.
The knowledge-testing-educational complex strikes back.

Boyatzis (1982) had said that "competency testing was distinct from, and superior to, assessment centers" (p. 1021). The actual quotation was, "Even assessment centers, as they are often designed, currently do not assess competencies as much as they assess performance of job functions. Some organizations have designed their assessment centers and selection techniques to assess competencies" (Boyatzis, 1982, p. 250). To be clear, assessment centers are a method for organizing, administering, and typically, returning data to participants. Assessment centers can be, and are, used to assess competencies, often incorporating the same operant exercises, such as the leaderless group discussion or CII. Even with the relatively high "efficiency" with which the CII can be used to assess competencies, the desirability of multimethod assessment, multievent sampling, and comprehensiveness of measures dictates the inclusion of the CII with other measures in research and applications.
Econometric Tools for Analyzing Market Outcomes

This paper outlines recently developed techniques for estimating the primitives needed to empirically analyze equilibrium interactions and their implications in oligopolistic markets. It is divided into an introduction and three sections; a section on estimating demand functions, a section on estimating production functions, and a section on estimating "dynamic" parameters (parameters estimated through their implications on the choice of controls which determine the distribution of future profits). The introduction provides an overview of how these primitives are used in typical I.O. applications, and explains how the individual sections are structured. The topics of the three sections have all been addressed in prior literature. Consequently each section begins with a review of the problems I.O. researchers encountered in using the prior approaches. The sections then continue with a fairly detailed explanation of the recent techniques and their relationship to the problems with the prior approaches. Hopefully the detail is rich enough to enable the reader to actually program up a version of the techniques and use them to analyze data. We conclude each section with a brief discussion of some of the problems with the more recent techniques. Here the emphasis is on when those problems are likely to be particularly important, and on recent research designed to overcome them when they are.
Explicit modeling subzero dehydration of living cells

As a cell suspension is being frozen, the contained cells will be dehydrated because the water activity in extracellular medium is being lowered. On the basis of ideal solution, the dehydration process has been modeled as the change of cell volumes with time or temperature, driven by the drop of water activity from intracellular to extracellular. At present, the volume change with temperature is the first derivative in widely used models, but the initial cell volume and the initial water activity are not in accordance with the model. Here, we show that this conflict comes from fact that the calculation of water activity is relative to the freezing point of pure water. From this point to the starting freezing point of solution, the cell volume remains constant for no dehydration. This conflict has been resolved as we choose the starting point of cell volume change as the reference temperature for the water activity calculation.
Congruence as Extensionality / Kongruenz als Extensionalität / La congruencia como extensionalidad / La congruence conçue comme extensionalité / A congruência como extensionalidade /

Abstract Within person-centered and experiential approaches, congruence is a central and evolving concept. It has been described both by Rogers and later theorists in a wide variety of ways. This paper aims to highlight and elaborate an under-examined aspect of congruence, namely congruence as extensionality. Extensionality conveys how the open, mature, adjusted person interacts with not just their self (internal) or others (relational), but the world (systemic). It involves the practice of personalizing perception and thinking critically and creatively to manage multiple realities. Extensionality has important implications for the development of person-centered and experiential approaches beyond the therapy room.
A Framework for Parallel Processing of Aggregate and Scalar Functions in Object-Relational DBMS1

Nowadays parallel object-relational DBMS are envisioned as the next great wave but there is still a lack of efficient implementation concepts for some parts of the proposed functionality. One of the current goals for parallel object-relational DBMS is to move towards higher performance. In our view the main potential for performance increases lies in providing additional optimization and execution information for ADTs, as queries can be executed much more efficiently if the developer teaches the DBMS part of the ADT semantics. Based on this insight we develop a framework that allows to process user-defined functions using data-parallelism, a topic not covered up to now. We describe the class of partitionable functions that can be processed in parallel with a good speedup. We also propose an extension which allows to speedup the processing of another large class of functions using parallel sorting. Functions that can be processed using our framework are for example often used in decision support queries on large data volumes like e.g. data warehouses. Hence a parallel execution is indispensable.
Effects of phorbol ester on contraction, intracellular pH and intracellular Ca2+ in isolated mammalian ventricular myocytes.

1. We have investigated the actions of certain phorbol esters on the intracellular pH, intracellular Ca2+ and contractility of isolated rat and guinea‐pig cardiac myocytes. Intracellular pH was measured using 2',7'‐bis(carboxyethyl)‐5(6)‐carboxyfluorescein (BCECF) and intracellular Ca2+ was measured using Fura‐2. 2. Application of the phorbol ester 12‐O‐tetradecanoylphorbol 13‐acetate (also called phorbol 12‐myristate 13‐acetate) (TPA) (which activates protein kinase C) to rat cardiac myocytes significantly increased cell shortening by 116 +/‐ 34% (n = 8) (p less than 0.02). The rate of change of cell length during contraction (i.e. +dL/dt) increased from 67.2 +/‐ 8.7 microns/s to 127.7 +/‐ 14.1 microns/s (n = 7). The rate of change of cell length during relaxation (‐dL/dt) increased from 55.8 +/‐ 7.4 microns/s to 118.9 +/‐ 12.1 microns/s (n = 7). Time to peak shortening was unchanged. 3. Application of 4 alpha‐phorbol 12,13‐didecanoate, which does not activate protein kinase C, did not affect rat myocyte contractility. An insignificant decrease in contractility (by 7.5 +/‐ 7.5%) was observed (n = 5). The positive inotropic effect of TPA may therefore be evoked through an activation of protein kinase C. 4. In rat myocytes we have measured the changes of pHi and contractility (cell shortening) during an alkalosis and acidosis induced by exposure to and subsequent removal of NH4Cl both in the presence and absence of TPA. Recovery times from an acid load were significantly (p less than 0.05) enhanced by 15.1 +/‐ 6.9% (n = 13) in the presence of TPA. Recovery times of cell shortening were also more rapid (p less than 0.05) by an average of 59.1 +/‐ 10.6% (n = 5) in the presence of TPA. Recovery times were unchanged in the presence of 4‐phorbol 12,13‐didecanoate (which does not activate protein kinase C). 5. Since pHi recovery of an isolated myocyte from an acid load is partially inhibited by the presence of 1 mM‐amiloride and inhibited by removing extracellular Na+ then it is suggested that, like pHi regulation in sheep heart Purkinje fibres, pHi recovery in rat cardiac ventricular myocytes is mainly through sarcolemmal Na(+)‐H+ exchange. We suggest that in the presence of TPA the Na(+)‐H+ exchange is stimulated. 6. The relationship between pHi and cell shortening is non‐linear as has been observed by others in whole tissue preparations. The presence of TPA shifts the relationship upwards such that at any one pHi, cell shortening is greater. (ABSTRACT TRUNCATED AT 400 WORDS)
A kinase-negative mutant of S49 mouse lymphoma cells is defective in posttranslational maturation of catalytic subunit of cyclic AMP-dependent protein kinase

Kinase-negative mutants of S49 mouse lymphoma cells, which lack detectable catalytic (C) subunit of cyclic AMP-dependent protein kinase, nevertheless contain cytoplasmic mRNAs for the two major forms of C subunit, C alpha and C beta. Investigation of the metabolism of C subunits in wild-type and mutant cells was undertaken to identify the step(s) at which C subunit expression was defective in kinase-negative cells. [35S]methionine-labeled C subunits from cytosolic fractions of wild-type S49 cells or C subunit-overexpressing cell lines were visualized by sodium dodecyl sulfate-polyacrylamide gel electrophoresis after purification by either affinity chromatography using a peptide inhibitor of C subunit as the ligand or immunoadsorption with an anti-C subunit antiserum. Immunoadsorption revealed electrophoretic forms of C alpha and C beta subunits that migrated faster than those detected in affinity-purified samples; this unexpected heterogeneity suggested that functional activation of C subunit may require posttranslational modification. Immunoadsorption of cytosolic fractions from wild-type cells labeled for various times with [35S]methionine revealed an additional posttranslational maturation step. The bulk of immunoadsorbable C subunit label in cells pulse-labeled for 5 min or less was in an insoluble fraction from which it could be solubilized with a detergent-containing buffer; solubilization of the newly synthesized material proceeded over an incubation period of about 10 min. The primary defect in kinase-negative cells appeared to be in this solubilization step, since about equal C subunit radioactivity was found in detergent extracts of wild-type and kinase-negative cells but very little was found in mutant cytosols. I speculate that an accessory factor required for proper folding of newly synthesized C subunit in defective in the kinase-negative cells.
Socioeconomic background, education, and labor force outcomes: evidence from a regional US sample

This paper examines the long-term association of family socioeconomic status (SES), educational, and labor force outcomes in a regional US longitudinal sample (N = 2264). The results offer insights into the mechanisms underlying the role of family SES in transitions from secondary schooling to early work experiences. It was found that the academic achievement gap associated with SES widens during secondary schooling due in part to course-level tracking. Family SES relates to college enrollment mainly via its association with academic gains in school, but also through family income and father’s occupational status. Family SES is weakly but significantly related to adult offspring’s earnings but more strongly related to occupational status. Educational qualifications and cognitive skills make independent contributions to the explanation of labor force outcomes.
Providing a low latency user experience in a high latency application

Through the use of particular visual effects, we provide a low latency user experience, even when extremely large latencies occur in an application. We demonstrate these effects in a wide-areadistributed virtual reality application. These effects include the use of motion blur, transparency, and defocusing. While the effects incur a performance penatty, the penalty is predictable, unlie the lag induced by network delays. Thus, we provide immediate feedback to each participant even when the network prevents information more useful than the fact that delays are occurring. When updates are finally receiv~ we use the same effects to provide coherent updates to the user’s information, without the jarring discontinuities that otherwise would confuse a participant’s understanding of the environment.
Associations Between the Residential Environment and Physical Activity in German College Students and the Role of Self-Efficacy as a Mediator

Social-ecological models suggest that influences on physical activity should be examined on multiple levels, but most of the empirical studies in this area have investigated the different levels separately. To integrate the different levels, we examined self-efficacy with respect to physical exercise as a mediator of the relation between environmental characteristics and physical activity. In a cross-sectional German study, 1,292 college students completed a questionnaire that included measures of their perceived residential environment, self-efficacy, and physical activity. Structural equation modeling was used to assess direct and indirect effects on physical activity. The cycling and walking network was directly positively associated with moderately intense physical activity. The network and trust in neighbors were indirectly positively associated with both moderately and vigorously intense physical activity mediated by self-efficacy. Our results support the importance of environmental influences on ph.
Correlates of men's sexual interest: a cross-cultural study.

INTRODUCTION Low sexual desire has been studied more extensively in women than in men. AIM The study aims to analyze the correlates of distressing lack of sexual interest and the self-assessed reasons for the lack of sexual interest among heterosexual men from three countries. METHODS A web-based survey was completed by 5,255 men aged 18-75 years from Portugal, Croatia, and Norway. MAIN OUTCOME MEASURES We used an item that assesses lack of sexual interest from the British NATSAL 2000. Anxiety and depression were measured with the SCL-ANX4 and SCL-DEP6. Relationship intimacy was measured using a five-item version of the Emotional Intimacy Scale. A shortened version of the Sexual Boredom Scale was used to assess proneness to sexual boredom in relation to the duration of relationship, and personal distress was evaluated using an item created for this study. RESULTS Distressing lack of sexual interest lasting at least 2 months in the previous year was reported by 14.4% of the participants. The most prevalent comorbidity among these men was erectile difficulty (48.7%). Men with low confidence levels in erectile function, not feeling attracted to the partner, and those in long-term relationships were more likely to have experienced lack of sexual interest than were men with high confidence levels and those who felt attracted to their partner and those in shorter-term relationships. Professional stress was the most frequently reported reason for lack of sexual interest. Sexual boredom as a result of a long-term relationship was significantly and negatively correlated with the level of intimacy (r = -0.351, P < 0.001) and sexual satisfaction (r = -0.497, P < 0.001). CONCLUSIONS Distressing lack of sexual interest in heterosexual men was associated with a number of intrapersonal (self-confidence in erectile function, stress), interpersonal (relationship duration, partner attractiveness), and sociocultural variables.
Vers des organisations réflexives : pour un autre management

Le mal-etre dans les organisations contemporaines n’est pas qu’un phenomene structurel, historique ou systemique. Ainsi, on ne peut faire disparaitre l’origine du pâtir ressenti par nombre de salaries en invoquant le travail invisible des « etres sans corps » que sont les institutions. La violence qui est perpetree dans le monde du travail a toujours un visage. Si chacun peut etre le relais de celle-ci, le collegue de bureau, le chef, vous et moi. , les managers et autres cadres (tous niveaux confondus) ont une responsabilite toute particuliere. Ils constituent les rouages essentiels par lesquels se diffuse, sur un mode ordinaire, une violence qui, parce que les pratiques professionnelles ne sont pas interrogees, se perpetue en toute tranquillite. Ainsi c’est avec la meilleure des bonnes consciences que des cadres peuvent « lyncher » un de leurs subordonnes. Pour en finir avec des pratiques violentes « innocentes » et cheminer vers des organisations reflexives, la posture clinico-critique, le travail de la negativite et le souci de la mise en intranquillite sont presentes comme des competences qui devraient etre mobilisees par les cadres et managers.
War, terror, girls and God: the construction of the religious Zionist female citizen in a state religious junior high school in Israel, 1999–2002

State religious schooling in Israel constitutes a fascinating setting for examining forces of conformity and resistance. This study, which examines the identity formation of adolescent girls and their teachers in this complex cultural‐educational setting during the Al‐Aksa Intifada (1999–2002), highlights the complexities of agency within a religious setting fraught with ethnic, religious, political and socio‐economic meanings. The study explores a complicated religious culture under attack in a state religious girls’ junior high school with a very mixed population. It examines the ways in which the school culture as an arm of religious Zionism seeks to take ownership of its female constituents, and the divergent forms of resistance that emerge in different subsections of the school society.