Miracle-dz/UniFAR-FTUs huggingface dataset:
Contributions to Differences Between On-Site and Factory-Measured Noise Levels of Power Transformers

Over the years, there have been a number of cases where users experienced higher noise levels of transformers on-site versus what was measured in the factory acceptance tests. In some of these cases, measurements have shown that a power transformer can have significantly different noise characteristics (both noise level and frequency spectrum) on-site compared to what was measured in the factory. This difference can range from a few decibels to more than 10 dB in some cases. Some of these differences are found to be caused by local environmental factors that influenced the on-site measurements. Others were caused by operating conditions on-site that are different from those of the factory tests. This paper presents results of investigations and measurements performed, over the past several years, on the main contributors to this difference. For each of these contributors, data are presented that demonstrate the impact of this contributor as well as quantify typical magnitudes of this impact. It is hoped that the material presented in this paper will assist users in: 1) understanding some of the pitfalls of on-site measurement of transformer noise; 2) how operating conditions contribute to the noise performance of transformers on-site; and 3) how significantly higher on-site noise levels can, in some cases, indicate an issue with the transformer or any of its components/accessories. It is also hoped that the material in this paper will contribute to industry standards/application guides on noise determination and abatement.
Methane production potentials, pathways, and communities of methanogens in vertical sediment profiles of river Sitka

Biological methanogenesis is linked to permanent water logged systems, e.g., rice field soils or lake sediments. In these systems the methanogenic community as well as the pathway of methane formation are well-described. By contrast, the methanogenic potential of river sediments is so far not well-investigated. Therefore, we analyzed (a) the methanogenic potential (incubation experiments), (b) the pathway of methane production (stable carbon isotopes and inhibitor studies), and (c) the methanogenic community composition (terminal restriction length polymorphism of mcrA) in depth profiles of sediment cores of River Sitka, Czech Republic. We found two depth-related distinct maxima for the methanogenic potentials (a) The pathway of methane production was dominated by hydrogenotrophic methanogenesis (b) The methanogenic community composition was similar in all depth layers (c) The main TRFs were representative for Methanosarcina, Methanosaeta, Methanobacterium, and Methanomicrobium species. The isotopic signals of acetate indicated a relative high contribution of chemolithotrophic acetogenesis to the acetate pool.
Experience, recursive awareness and understanding in autism spectrum disorders: insights of parents and teachers in Singapore

Provision of an individually responsive education requires a comprehensive understanding of the inner worlds of learners, such as their feelings and thoughts. However, this is difficult to achieve when learners, such as those with Autism Spectrum Disorders (ASD) and cognitive difficulties, have problems with communication. To address this issue, the current exploratory descriptive study sought the views of 133 Singaporean parents and teachers of school-age learners with ASD and cognitive difficulties regarding the inner experience of their children and students. The findings highlight the variety of abilities and difficulties found in how these learners experience their own mental states and understand those of others. These abilities and difficulties are characterized according to type of mental state and analysed in line with three qualia, those of experience, recursive awareness and understanding. The findings indicate that learners show a greater awareness of their own mental states compared to their ability to understand these same mental states in others. Educational implications are discussed.
Health care costs associated with Australian tertiary inflammatory bowel disease care

Abstract Introduction: We aimed to describe the total costs of illness for IBD patients and compare the costs of patients with active disease to those with inactive disease. Materials and methods: Resource use for IBD management was itemized for attributable costs (AUD) among all IBD patients over a 12-month period at an Australian hospital. Results: One hundred and eighty-three patients were included (87 ulcerative colitis (UC); 93 Crohn’s disease (CD); three IBD-unclassified). The median (IQR) annual overall cost was higher in the CD versus UC group ($15,648 versus $5017; p < .001). The difference in cost between CD and UC was influenced by the difference in outpatient costs for CD patients $9602 ($4311–$29,805) versus $4867 ($3220–$7249), p < . 001). The cost of treating patients with active disease was $3461 ($1607–$11,771) and was higher in the CD versus the UC group ($6098 ($2168–$16,471) versus $1638 ($1401–$3767); p = . 026) and was influenced by inpatient admissions. The cost of treating patients in remission was $2090 ($1552–$12,954) and was higher in the CD versus the UC group [$7977 ($1579–$14,304) versus $1848 ($1508–$6601); p = . 236]. Conclusions: There is a discrepancy in costs of inpatient versus outpatient IBD management and treating active disease compared with disease in remission. Proactive care may help prevent disease reaching a severity whereby reactive management of active disease is required.
Loose-Ordering Consistency for persistent memory

Emerging non-volatile memory (NVM) technologies enable data persistence at the main memory level at access speeds close to DRAM. In such persistent memories, memory writes need to be performed in strict order to satisfy storage consistency requirements and enable correct recovery from system crashes. Unfortunately, adhering to a strict order for writes to persistent memory significantly degrades system performance as it requires flushing dirty data blocks from CPU caches and waiting for their completion at the main memory in the order specified by the program. This paper introduces a new mechanism, called Loose-Ordering Consistency (LOC), that satisfies the ordering requirements of persistent memory writes at significantly lower performance degradation than state-of-the-art mechanisms. LOC consists of two key techniques. First, Eager Commit reduces the commit overhead for writes within a transaction by eliminating the need to perform a persistent commit record write at the end of a transaction. We do so by ensuring that we can determine the status of all committed transactions during recovery by storing necessary metadata information statically with blocks of data written to memory. Second, Speculative Persistence relaxes the ordering of writes between transactions by allowing writes to be speculatively written to persistent memory. A speculative write is made visible to software only after its associated transaction commits. To enable this, our mechanism requires the tracking of committed transaction ID and support for multi-versioning in the CPU cache. Our evaluations show that LOC reduces the average performance overhead of strict write ordering from 66.9% to 34.9% on a variety of workloads.
Modeling study of thermoelectric SiGe nanocomposites

Nanocomposite thermoelectric materials have attracted much attention recently due to experimental demonstrations of improved thermoelectric properties over those of the corresponding bulk material. In order to better understand the reported data and to gain insight into transport in nanocomposites, we use the Boltzmann transport equation under the relaxation-time approximation to calculate the thermoelectric properties of $n$-type and $p$-type SiGe nanocomposites. We account for the strong grain-boundary scattering mechanism in nanocomposites using phonon and electron grain-boundary scattering models. The results from this analysis are in excellent agreement with recently reported measurements for the $n$-type nanocomposite but the experimental Seebeck coefficient for the $p$-type nanocomposite is approximately 25% higher than the model's prediction. The reason for this discrepancy is not clear at the present time and warrants further investigation. Using new mobility measurements and the model, we find that dopant precipitation is an important process in both $n$-type and $p$-type nanocomposites, in contrast to bulk SiGe, where dopant precipitation is most significant only in $n$-type materials. The model also shows that the potential barrier at the grain boundary required to explain the data is several times larger than the value estimated using the Poisson equation, indicating the presence of crystal defects in the material. This suggests that an improvement in mobility is possible by reducing the number of defects or reducing the number of trapping states at the grain boundaries.
Family-Friendly Working: What a Performance! An Analysis of the Relationship Between the Availability of Family-Friendly Policies and Establishment Performance

This paper uses the Management and Employee Questionnaires from the 1998 Workplace Employee Relations Survey (WERS98) to consider whether the performance of workplaces which offer a range of family-friendly policies are superior to that of workplaces without such practices. It is found that in almost all cases where there is a significant relationship between the use of a family-friendly practice and workplace performance, this relationship is positive. In addition, it appears that workplaces which offer an extensive range of family-friendly policies are much more likely to have above-average performance than those with no such practices. The paper moves on to consider whether employers offering policies which enable employees with families to maintain a full-time presence in the workplace e.g. a workplace nursery, have better performance than those which offer policies which result in reduced-visibility e.g. working from home, part-time work. The evidence from WERS98 suggests that this is indeed the case.
The Asexual Pathogen Aspergillus fumigatus Expresses Functional Determinants of Aspergillus nidulans Sexual Development

ABSTRACT The major fungal pathogen of humans, Aspergillus fumigatus, lacks a defined sexual cycle, although the presence of genes encoding putative mating type idiomorphs and regulators of Aspergillus sexual development heightens the potential for cryptic sexuality in this deuteromycete. To test the functionality of these genetic determinants, we transferred the alpha box-encoding mat1-1 idiomorph from an A. fumigatus isolate to the homothallic fertile species Aspergillus nidulans. Abundant formation of fruiting bodies (cleistothecia) containing viable ascospores establishes functionality of this mating type gene product in the transgenic strain. Using a similar approach, we also established that the conserved transcriptional regulator from A. fumigatus, the nsdD gene product, can act as a functional, positively acting factor for A. nidulans cleistothecium development; moreover, high-level expression of NsdD in the endogenous host A. fumigatus profoundly alters hyphal development by triggering the formation of coiled hyphae. Our findings demonstrate that the presumably asexual pathogen A. fumigatus encodes functional regulators of mating and sexual development, thereby potentiating the case for cryptic sexuality in this fungal pathogen.
Voltage-Boosted Synchronizers

With a specified Mean Timing Between Failure (MTBF), the metastability resolution time of synchronizers possibly constrains the system performance. To enhance metastability resolution time under single low-voltage supply environments, Voltage-Boosted Synchronizers (VBSs) consisting of a basic minimum-sized Jamb latch and a switched-capacitor-based charge pump are proposed. The capacitor of the charge pump is sized 13 times the area of the Jamb latch. Two powering strategies of the charge pump, namely Metastability-driven VBS (MVBS) and Clock-driven VBS (CVBS), are proposed. For a 1-year MTBF specification, MVBS and CVBS show 2.0-2.7 and 5.1-9.8 times the performance improvement over the basic Jamb latch, respectively, without incurring large power consumption.
Finding Common Ground: A Survey of Capacitive Sensing in Human-Computer Interaction

For more than two decades, capacitive sensing has played a prominent role in human-computer interaction research. Capacitive sensing has become ubiquitous on mobile, wearable, and stationary devices - enabling fundamentally new interaction techniques on, above, and around them. The research community has also enabled human position estimation and whole-body gestural interaction in instrumented environments. However, the broad field of capacitive sensing research has become fragmented by different approaches and terminology used across the various domains. This paper strives to unify the field by advocating consistent terminology and proposing a new taxonomy to classify capacitive sensing approaches. Our extensive survey provides an analysis and review of past research and identifies challenges for future work. We aim to create a common understanding within the field of human-computer interaction, for researchers and practitioners alike, and to stimulate and facilitate future research in capacitive sensing.
Modelling Cross-Gender and Sexual Relations: Exploring the Soul Buddyz Edutainment Initiative in South Africa

HIV/AIDS among youth is a serious problem in South Africa. Cross-gender relations and associated constructs surrounding masculinity/femininity and sexuality are increasingly recognized as at the heart of the issue. Growing attention has thus been given to developing initiatives geared towards children and very young adolescents (VYAs), aimed at addressing attitudes and behaviours surrounding gender and sexuality. This paper explored the representations of “positive” cross-gender relations, as well as associated constructs, in the Soul Buddyz edutainment initiative primarily geared towards 8-12 year-olds, and intended to provide “positive” role models for girls and boys. Pertinent Soul Buddyz material was explored through methods of narrative and frame analysis, from a position informed by social constructionism and theoretical tenets of Michel Foucault. Findings were then situated within a broader framework, with reference made to the formative research undertaken for the development of Soul Buddyz, as well as other relevant studies concerning children and youth. The overarching aim of this paper was to raise questions in reference to HIV/AIDS prevention initiatives dealing with cross-gender relations and associated constructs, critical reflection upon these issues being considered as crucial within the context of the HIV/AIDS epidemic, and for potentially strengthening prevention initiatives.
A position and stiffness control strategy for variable stiffness actuators

Variable stiffness actuators (VSAs) have been introduced to improve, at the design level, the safety and the energy efficiency of the new generation of robots that have to interact closely with humans. A wide variety of design solutions have recently been proposed, and a common factor in most of the VSAs is the introduction of a flexible transmission with varying stiffness. This, from the control perspective, usually implies a nonlinear actuation plant with varying dynamics following time-varying parameters, which requires more complex control strategies with respect to those developed for flexible joints with a constant stiffness. For this reason, this paper proposes an approach for controlling the link position and stiffness of a VSA. The link positioning relies on a LQR-based gain scheduling approach useful for continuously adjusting the control effort based on the current stiffness of the flexible transmission. The stiffness perceived at the output link is adjusted to match the varying task requirements through the combination of the positioning gains and the mechanical stiffness. The stability of the overall strategy is briefly discussed. The effectiveness of the controller in terms of tracking performance and stiffness adjustment is verified through experiments on the Actuator with Adjustable Stiffness (AwAS).
Role of phosphodiesterase and adenylate cyclase isozymes in murine colonic glucagon-like peptide 1 secreting cells

Glucagon‐like peptide‐1 (GLP‐1) is secreted from enteroendocrine L‐cells after food intake. Increasing GLP‐1 signalling either through inhibition of the GLP‐1 degrading enzyme dipeptidyl‐peptidase IV or injection of GLP‐1‐mimetics has recently been successfully introduced for the treatment of type 2 diabetes. Boosting secretion from the L‐cell has so far not been exploited, due to our incomplete understanding of L‐cell physiology. Elevation of cyclic adenosine monophosphate (cAMP) has been shown to be a strong stimulus for GLP‐1 secretion and here we investigate the activities of adenylate cyclase (AC) and phosphodiesterase (PDE) isozymes likely to shape cAMP responses in L‐cells.
Cognitive Reserve Index questionnaire (CRIq): a new instrument for measuring cognitive reserve

Background and aims: The concept of “reserve” has been used to explain the difference between individuals in their capacity to cope with or compensate for pathology. Brain reserve refers to structural aspects of the brain, such as brain size and synapse count. Cognitive reserve is the ability to optimize and maximize performance through two mechanisms: recruitment of brain networks, and/or compensation by alternative cognitive strategies. The aim of the present research was to devise an instrument for comprehensive assessment and measurement of the quantity of cognitive reserve accumulated by individuals throughout their lifespan. Methods: A new approach using the Cognitive Reserve Index questionnaire (CRIq) was developed and tested in a sample of 588 healthy individuals, from 18 to 102 years old, stratified by age (Young, Adults, Elderly) and gender. The CRIq includes demographic data and items grouped into three sections: education, working activity and leisure time, each of which returns a subscore. The WAIS Vocabulary test and TIB were also administered. Results: The main descriptive features and some inferential results are described. Intelligence was only moderately correlated with cognitive reserve, stressing the distinction between these two concepts. Age and gender significantly affected CRIq scores, whereas no effect emerged from their interaction. Adults showed a higher score than Young and Elderly. Conclusions: This study provides a new instrument for a standardized measure of the cognitive reserve accumulated by individuals through their lifespan. The potential use of the CRIq in both experimental research and clinical practice is discussed.
Characterization of the Pichia pastoris Protein-O-mannosyltransferase Gene Family

The methylotrophic yeast, Pichia pastoris , is an important organism used for the production of therapeutic proteins. However, the presence of fungal-like glycans, either N-linked or O-linked, can elicit an immune response or enable the expressed protein to bind to mannose receptors, thus reducing their efficacy. Previously we have reported the elimination of β-linked glycans in this organism. In the current report we have focused on reducing the O-linked mannose content of proteins produced in P . pastoris , thereby reducing the potential to bind to mannose receptors. The initial step in the synthesis of O-linked glycans in P . pastoris is the transfer of mannose from dolichol-phosphomannose to a target protein in the yeast secretory pathway by members of the protein-O-mannosyltransferase (PMT) family. In this report we identify and characterize the members of the P . pastoris PMT family. Like Candida albicans, P . pastoris has five PMT genes. Based on sequence homology, these PMTs can be grouped into three sub-families, with both PMT1 and PMT2 sub-families possessing two members each (PMT1 and PMT5, and PMT2 and PMT6, respectively). The remaining sub-family, PMT4, has only one member (PMT4). Through gene knockouts we show that PMT1 and PMT2 each play a significant role in O-glycosylation. Both, by gene knockouts and the use of Pmt inhibitors we were able to significantly reduce not only the degree of O-mannosylation, but also the chain-length of these glycans. Taken together, this reduction of O-glycosylation represents an important step forward in developing the P . pastoris platform as a suitable system for the production of therapeutic glycoproteins.
Characterization of an NGF–P-TrkA Retrograde-Signaling Complex and Age-Dependent Regulation of TrkA Phosphorylation in Sympathetic Neurons

Nerve growth factor (NGF) is a target-derived trophic factor for developing sympathetic and cutaneous sensory neurons. NGF promotes growth and survival of neurons via activation of the receptor tyrosine kinase TrkA. We used compartmentalized cultures of sympathetic neurons to address the mechanism of NGF signaling from distal axons and terminals to proximal axons and cell bodies. Our results demonstrate that an NGF–phospho-TrkA (NGF–P-TrkA)–signaling complex forms in distal axons and is retrogradely transported as a complex to cell bodies of sympathetic neurons. Although a minor fraction of both NGF and TrkA is retrogradely transported, a large fraction of the NGF that is retrogradely transported is found complexed with retrogradely transported TrkA. Interestingly, the metabolism of the P-TrkA complex is dramatically different in young, NGF-dependent sympathetic neurons as compared to older, NGF-independent sympathetic neurons. After withdrawal of NGF from distal axons of young neurons, P-TrkA within distal axons, as well as within proximal axons and cell bodies, dephosphorylates rapidly. In contrast, after withdrawal of NGF from distal axons of older neurons, P-TrkA within distal axons dephosphorylates completely, although more slowly than that in young neurons, whereas dephosphorylation of P-TrkA within proximal axons and cell bodies occurs markedly more slowly, with at least one-half of the level of P-TrkA remaining 2 d after NGF withdrawal. Thus, P-TrkA within the cell bodies of young, NGF-dependent sympathetic neurons is derived from distal axons. A more stable P-TrkA complex within cell bodies of mature sympathetic neurons may contribute to the acquisition of NGF independence for survival of mature sympathetic neurons.
Non-BPS solutions of the noncommutative CP 1 model in 2 + 1 dimensions

We find non-BPS solutions of the noncommutative CP1 model in 2+1 dimensions. These solutions correspond to soliton anti-soliton configurations. We show that the one-soliton one-anti-soliton solution is unstable when the distance between the soliton and the anti-soliton is small. We also construct time-dependent solutions and other types of solutions.
Improving the effectiveness of information retrieval with local context analysis

Techniques for automatic query expansion have been extensively studied in information research as a means of addressing the word mismatch between queries and documents. These techniques can be categorized as either global or local. While global techniques rely on analysis of a whole collection to discover word relationships, local techniques emphasize analysis of the top-ranked documents retrieved for a query. While local techniques have shown to be more effective that global techniques in general, existing local techniques are not robust and can seriously hurt retrieved when few of the retrieval documents are relevant. We propose a new technique, called local context analysis, which selects expansion terms based on cooccurrence with the query terms within the top-ranked documents. Experiments on a number of collections, both English and non-English, show that local context analysis offers more effective and consistent retrieval results.