Miracle-dz/UniFAR-FTUs huggingface dataset:
A Socio-pragmatic Analysis of Women Expressive Utterances in Bad Moms Movie

This research focuses on expressive utterances showed by women in Bad Moms movie. This research has two major bjectives (1) to describe the intentions of women expressive utterance, and (2) to describe the politeness strategies of women expressive utterances in Bad Moms movie. This research is qualitative research. The data in this research are utterances showed by women that support the occurrence of expressive utterances. The data source is Bad Moms anuscript by John Lucas and Scott Moore. The data are collected by using documentation and observation. The result of the research shows that (1) fifteen types of expressiveutterance intention used by women in Bad Moms movie. 13 utterances belong to praising (12%), 14 utterances belong to apology (13%), 3 utterances belong to expressing sympathy (3%), 7 utterances belong to expressing frightened (6%), 2 tterances belong to expressing hope (2%), 2 utterances belong to expressing hopeless (2%), 4 utterances belong to expressing tired (4%), 5 utterances belong to expressing gratitude (5%), 3 utterances belong to expressing proud (3%), 11 utterances belong to expressing pleasure (10%), 17 tterances belong to expressing displeasure (15%), 4 utterances belong to expressing love (4%), 5 utterances belong to expressing like (5%), 9 utterances belong to expressing dislike (8%), 9 utterances belong to expressing surprised (8%). The dominant type of the intention of expressive utterance used by women is expressing displeasure (15%). It can be concluded that angry characteristic that is dominant used by men,it is dominant too at women in this movie. Women characters in this movie based on different context and situation usually use the feeling of being upset and annoyed. (2) the researcher found four types of politeness strategies in Bad Moms movie based on Brown and Levinson’s theory: 48 terances belong to bald on record strategy (45%), 22 utterancesbelong to positive politeness strategy (20%), 29 utterances belong to negative politeness strategy (27%), and 9 utterances belong to off record strategy (8%). The dominant of liteness strategy of expressive utterance used by women is bald on record strategy (45%). It can be concluded that women are not always more polite in using language than men. Women do not attempt to minimize the threat to the hearer’s face because the speaker wishes to maximize the efficiency of the utterance.
Genetic control of the immune response to myoglobins. Both low and high responder T cells tolerant to the other major histocompatibility complex help high but not low responder B cells

We sought to examine the role of immune response (Ir) genes in helper T cells. To eliminate allogeneic effects, we used neonatally tolerized mice. The results bear not only on the mechanism of Ir genes, but also on the development of the T cell repertoire. B 10.BR (H-2(k)) or C57BL/10 (H-2(b)) mice, which were low responders to myoglobin (Mb), were neonatally tolerized to high responder H-2(d) alloantigens, and B10.D2 mice, which were high responders to Mb, were neonatally tolerized to low responder H-2(k) or H-2(b) alloantigens. Spleen cells from these tolerized mice did not show any reactivity in mixed-lymphocyte reaction or cell-mediated lympholysis against alloantigens used in tolerization. Mb-immune F(1) B cells were helped comparably by Mb-immune tolerized low or high responder T cells. Thus, low responder T cells functioned equivalently to high responder T cells. The failure of nonimmune T cells from tolerized low responder mice to help F(1) B cells and antigen-presenting cells (APC) indicated that collaboration between B10.BR or C57BL/10 T cells and F(1) B cells was not caused by a positive allogeneic effect. Spleen cells from tolerized mice were contaminated with 2-4 percent chimeric F(1) cells, as judged by fluorescence-activated cell sorter analysis, and no F(1) alloantigens were detectable in the thymus. However, removal of chimeric F(1) T cells from the tolerized cell population by treatment with anti-H-2 and complement did not change the helper activity of tolerized low responder T cells. These data indicated that helper activity in the T cell population from low responder mice was not due to F(1) cells. Also, the level of contamination was not sufficient to quantitatively account for the help. In examining the genetic restriction of these tolerized T cells, we found that T cells from tolerized low responder B10.BR or C57BL/10 mice helped F(1) or high responder B10.D2 B cells and APC but not syngeneic B10.BR or C57BL/10 B cells and APC, which were immunized with Mb-coupled fowl gamma globulin instead of Mb to prime low responder B cells with Mb. On the other hand, high responder B 10.D2 tolerized T cells helped syngeneic B 10.D2 B cells but not allogeneic low responder B10.BR B cells. These data indicated that clones of helper T cells specific for Mb exist in low responder mice, and these are not phenotypically different from those in high responder mice, in that both help high responder and F(1) but not low responder B cells and APC. These data are discussed in terms of the mechanism for Ir gene control, and the mechanism of T cell repertoire development- whether intra- or extrathymically-in neonatally tolerized mice.
Effect of disparity on the perception of motion-defined contours

We present three experiments that explored the effect of binocular disparity on the perception of contours defined by motion in a Spatiotemporal Boundary Formation. Depending on the disparity, the stimulus is perceived as an object that moves behind a holed surface (occluded configuration) or as a luminous transparency that moves over a surface that contains dots (occluding configuration). In all of the experiments, we used a Vernier task to assess the strength of contour perception. In the first experiment, we measured acuity as a function of disparity for a range of speeds and dot densities. The results showed that, despite the difference in the percepts, acuity was similar in both situations, replicating the dependence on speed and dot density demonstrated in previous studies. In the second experiment, the results showed that the dynamics of contour integration were identical for both occluded and occluding configurations. In the third experiment, we tested whether the mechanism of contour integration works independently from the interpretation of the scene. In this experiment, we inverted the disparity during stimulus presentation so that the stimulus switched between occluded and occluding configurations. The results showed that the switch of the depth order increased the threshold to the value obtained with a shorter presentation time. This might be produced by a resetting of the integration process driven by the change of depth order. The results are discussed within a conceptual model that places the process of contour integration in the context of the perception of objects in a Spatiotemporal Boundary Formation.
Tumor Necrosis Factor Alpha Gene Regulation: Enhancement of C/EBPβ-Induced Activation by c-Jun

ABSTRACT Tumor necrosis factor alpha (TNFα) is a key regulatory cytokine whose expression is controlled by a complex set of stimuli in a variety of cell types. Previously, we found that the monocyte/macrophage-enriched nuclear transcription factor C/EBPβ played an important role in the regulation of the TNFα gene in myelomonocytic cells. Abundant evidence suggests that other transcription factors participate as well. Here we have analyzed interactions between C/EBPβ and c-Jun, a component of the ubiquitously expressed AP-1 complex. In phorbol myristate acetate (PMA)-treated Jurkat T cells, which did not possess endogenous C/EBPβ, expression of c-Jun by itself had relatively little effect on TNFα promoter activity. However, the combination of C/EBPβ and c-Jun was synergistic, resulting in greater than 130-fold activation. This effect required both the leucine zipper and DNA binding domains, but not the transactivation domain, of c-Jun, plus the AP-1 binding site centered 102/103 bp upstream of the transcription start site in the TNFα promoter. To determine if C/EBPβ and c-Jun might cooperate to regulate the cellular TNFα gene in myelomonocytic cells, U937 cells that possess endogenous C/EBPβ and were stably transfected with either wild-type c-Jun or the transactivation domain deletion mutant (TAM-67) were examined. U937 cells expressing ectopic wild-type c-Jun or TAM-67 secreted over threefold more TNFα than the control line in response to PMA plus lipopolysaccharide. Transient transfection of the U937 cells expressing TAM-67 suggested that TAM-67 binding to the −106/−99-bp AP-1 binding site cooperated with endogenous C/EBPβ in the activation of the −120 TNFα promoter-reporter. DNA binding assays using oligonucleotides derived from the TNFα promoter suggested that C/EBPβ and c-Jun interact in vitro and that the interaction may be DNA dependent. Our data demonstrate that the TNFα gene is regulated by the interaction of the ubiquitous AP-1 complex protein c-Jun and the monocyte/macrophage-enriched transcription factor C/EBPβ and that this interaction contributes to the expression of the cellular TNFα gene in myelomonocytic cells. This interaction was unique in that it did not require the c-Jun transactivation domain, providing new insight into the cell-type-specific regulation of the TNFα gene.
A robust point detection algorithm based on wavelet transform for visual tracking

Visual tracking is one of the hot research topics in computer vision in recent years. It has been widely used in many vision applications, such as traffic surveillance, anti-terrorism. However, there are still challenges for visual tracking, like illumination change, object occlusion, appearance deformation, etc. This paper proposes a robust point detection algorithm based on wavelet transform for visual tracking. First, the input image patch that includes the tracking object is decomposed by wavelet transform with several levels and the wavelet coefficients are obtained. The wavelet coefficients are then analyzed and the points that hold the local maximal wavelet coefficients are determined as the robust points for tracking. Finally, the proposed method is integrated to the Tracking Learning Detection (TLD) framework, which not only improves the tracking precision, but also reduces the false detection. Experimental results showed that the new algorithm outperformed the TLD method with respect to the precision, recall, and f-measure.
The Role of the Thymus and Recent Thymic Migrants in the Maintenance of the Adult Peripheral Lymphocyte Pool

The thymus is essential for the initial seeding of T cells to the periphery, but its role in maintaining the adult T cell pool remains poorly defined. We investigated whether changes to the rate of T cell export could form part of the mechanism(s) controlling the homeostatic regulation of the size and composition of the peripheral T cell pool. Using neonatal thymi grafted under the kidney capsule, we found that irrespective of whether the pool was oversupplied (by thymic grafts) or undersupplied (due to neonatal thymectomy), the thymic export rate was constant from both the host and graft thymus, and the periphery remained constant in size. Recent thymic emigrants (RTE) were also tracked to determine the extent of their acceptance into the T cell pool of a normal mouse. As a population, RTE are phenotypically mature, but were distinct from resident T cells in the periphery, being released in a CD4/CD8 ratio approximately twice that of established peripheral T cells. This export ratio is similar to that of T cells in the mature thymic compartment, but soon after entry into the periphery, the ratio falls, indicating separate thymic and peripheral regulation of the CD4/CD8 ratio. RTE may also be preferentially incorporated into the periphery, causing displacement of resident T cells, thus maintaining the size of the peripheral pool. Although not vital for the maintenance of a functional T cell pool, the acceptance of RTE in a “full” peripheral pool would ensure that the T cell receptor repertoire is kept diverse and that the T cell population encompasses a broad range of naive as well as memory T cells.
Adaptive Reprogramming for Databases on Heterogeneous Processors

It is clear by now that modern processing hardware gets increasingly heterogeneous, which forces data processing algorithms to care about the underlying hardware. However, current approaches for implementing data intensive operators (e.g., in database systems) either cause enormous programming effort for tuning one algorithm to several processors (the hardware-sensitive way), or do not fully exploit possible performance possibilities because of an abstract operator description (the hardware-oblivious way). In this thesis, we propose an algorithm optimizer, which automatically tunes a hardware-oblivious operator description to the underlying hardware. This way, the DBMS can rewrite its operator code until it runs optimally on the given hardware.
Health-Related Quality of Life in Children and Adolescents with Hereditary Bleeding Disorders and in Children and Adolescents with Stroke: Cross-Sectional Comparison to Siblings and Peers

Objectives. To investigate self-reported health-related quality of life (HrQoL) in children and adolescents with chronic medical conditions compared with siblings/peers. Methods. Group 1 (6 treatment centers) consisted of 74 children/adolescents aged 8–16 years with hereditary bleeding disorders (HBD), 12 siblings, and 34 peers. Group 2 (one treatment center) consisted of 70 children/adolescents with stroke/transient ischemic attack, 14 siblings, and 72 peers. HrQoL was assessed with the “revised KINDer Lebensqualitätsfragebogen” (KINDL-R) questionnaire. Multivariate analyses within groups were done by one-way ANOVA and post hoc pairwise single comparisons by Student's t-tests. Adjusted pairwise comparisons were done by hierarchical linear regressions with individuals nested within treatment centers (group 1) and by linear regressions (group 2), respectively. Results. No differences were found in multivariate analyses of self-reported HrQoL in group 1, while in group 2 differences occurred in overall wellbeing and all subdimensions. These differences were due to differences between patients and peers. After adjusting for age, gender, number of siblings, and treatment center these differences persisted regarding self-worth (p = .0040) and friend-related wellbeing (p < .001). Conclusions. In children with HBD, HrQoL was comparable to siblings and peers. In children with stroke/TIA HrQoL was comparable to siblings while peers, independently of relevant confounder, showed better self-worth and friend-related wellbeing.
Bayesian-based Decision Support System for Water Distribution Systems

The efficient long term management of large-scale public funded assets is an area of growing importance. Ageing infrastructure, growth, and limited capital all result in the need for more robust and rigorous methodology to prioritise rehabilitation and renewal decisions and as importantly, to forecast future expenditure requirements. The overall objective of this research is to develop a Bayesian-based decision support system that will facilitate the identification of efficient asset management policies. The Bayesian approach enables us to formally incorporate, express, and update our uncertainty when determining such policies. This is particularly relevant for water utilities that have incomplete or unreliable historical failure data sets and as a consequence rely heavily on past engineering experience. An object oriented discrete event simulation has been developed to analyse existing maintenance policies, test the Bayesian methodology, and to develop and identify improved maintenance policies. This paper focuses on the areas of research relating to the long term management of water distribution systems and in particular, will present: 1) an overview of the Bayesian approach, 2) development and initial results for an object oriented discrete event simulation, and 3) proposed future research and development.
Edge Detection in Digital Images Corrupted by Salt and Pepper Noise using Adaptive Neuro- Fuzzy Inference System (ANFIS)

This paper presents an Edge Detection technique for images corrupted by salt and pepper noise, which is based on an Adaptive Neuro-Fuzzy Inference System (ANFIS). This proposed technique first of all filters out the noise by Noise Adaptive Fuzzy Switching Median Filter (NAFSMF) and then find the edges using proposed ANFIS based edge detector. The training pattern for edge detection is proposed to optimize the internal parameters of the ANFIS based edge detector. The edges are directly determined by the proposed ANFIS based edge detector. This proposed edge detector is then compared with popular edge detectors Sobel, Roberts, Prewitt on the basis of performance metrics PSNR (Peak Signal to Noise Ratio), MSE (Mean Square Error) and No. of Edges detected.
Simplified optimal line selection for acoustic localization in the presence of reverberation

The problem of acoustic source position estimation in reverberant environments has been tackled in different ways. The authors have recently proposed a valid solution which shows good results even in very hard conditions in terms of reverberation. Although the estimator is indicated for a real-time implementation as long as it can be solved in a closed form, in this paper the authors present a simplified version of the estimator in order to significantly reduce the complexity of the previous realization. A direct comparison among the two estimators will be shown, additionally the estimator can be considered also a robust time difference of arrival estimator in the presence of reverberation.
Clonal Human Fetal Ventral Mesencephalic Dopaminergic Neuron Precursors for Cell Therapy Research

A major challenge for further development of drug screening procedures, cell replacement therapies and developmental studies is the identification of expandable human stem cells able to generate the cell types needed. We have previously reported the generation of an immortalized polyclonal neural stem cell (NSC) line derived from the human fetal ventral mesencephalon (hVM1). This line has been biochemically, genetically, immunocytochemically and electrophysiologically characterized to document its usefulness as a model system for the generation of A9 dopaminergic neurons (DAn). Long-term in vivo transplantation studies in parkinsonian rats showed that the grafts do not mature evenly. We reasoned that diverse clones in the hVM1 line might have different abilities to differentiate. In the present study, we have analyzed 9 hVM1 clones selected on the basis of their TH generation potential and, based on the number of v-myc copies, v-myc down-regulation after in vitro differentiation, in vivo cell cycle exit, TH+ neuron generation and expression of a neuronal mature marker (hNSE), we selected two clones for further in vivo PD cell replacement studies. The conclusion is that homogeneity and clonality of characterized NSCs allow transplantation of cells with controlled properties, which should help in the design of long-term in vivo experiments.
How do you feel about "dancing queen"?: deriving mood & theme annotations from user tags

Web 2.0 enables information sharing, collaboration among users and most notably supports active participation and creativity of the users. As a result, a huge amount of manually created metadata describing all kinds of resources is now available. Such semantically rich user generated annotations are especially valuable for digital libraries covering multimedia resources such as music, where these metadata enable retrieval relying not only on content-based (low level) features, but also on the textual descriptions represented by tags. However, if we analyze the annotations users generate for music tracks, we find them heavily biased towards genre. Previous work investigating the types of user provided annotations for music tracks showed that the types of tags which would be really beneficial for supporting retrieval - usage (theme) and opinion (mood) tags - are often neglected by users in the annotation rocess. In this paper we address exactly this problem: in order to support users in tagging and to fill these gaps in the tag space, we develop algorithms for recommending mood and theme annotations. Our methods exploit the available user annotations, the lyrics of music tracks, as well as combinations of both. We also compare the results for our recommended mood / theme annotations against genre and style recommendations - a much easier and already studied task. Besides evaluating against an expert (AllMusic.com) ground truth, we evaluate the quality of our recommended tags through a Facebook-based user study. Our results are very promising both in comparison to experts as well as users and provide interesting insights into possible extensions for music tagging systems to support music search.
Long-latency, inhibitory spinal pathway to ankle flexors activated by homonymous group 1 afferents.

Inhibitory feedback from sensory pathways is important for controlling movement. Here, we characterize, for the first time, a long-latency, inhibitory spinal pathway to ankle flexors that is activated by low-threshold homonymous afferents. To examine this inhibitory pathway in uninjured, healthy participants, we suppressed motor-evoked potentials (MEPs), produced in the tibialis anterior (TA), by a prior stimulation to the homonymous common peroneal nerve (CPN). The TA MEP was suppressed by a triple-pulse stimulation to the CPN, applied 40, 50, and 60 ms earlier and at intensities of 0.5-0.7 times motor threshold (average suppression of test MEP was 33%). Whereas the triple-pulse stimulation was below M-wave and H-reflex threshold, it produced a long-latency inhibition of background muscle activity, approximately 65-115 ms after the CPN stimulation, a time period that overlapped with the test MEP. However, not all of the MEP suppression could be accounted for by this decrease in background muscle activity. Evoked responses from direct activation of the corticospinal tract, at the level of the brain stem or thoracic spinal cord, were also suppressed by low-threshold CPN stimulation. Our findings suggest that low-threshold muscle and cutaneous afferents from the CPN activate a long-latency, homonymous spinal inhibitory pathway to TA motoneurons. We propose that inhibitory feedback from spinal networks, activated by low-threshold homonymous afferents, helps regulate the activation of flexor motoneurons by the corticospinal tract.