Miracle-dz/UniFAR-FTUs huggingface dataset:
Korean Journal for Food Science of Animal Resources Use of Atmospheric Pressure Cold Plasma for Meat Industry

Novel, effective methods to control and prevent spoilage and contamination by pathogenic microorganisms in meat and meat products are in constant demand. Non-thermal pasteurization is an ideal method for the preservation of meat and meat products because it does not use heat during the pasteurization process. Atmospheric pressure cold plasma (APCP) is a new technology for the non-thermal pasteurization of meat and meat products. Several recent studies have shown that APCP treatment reduces the number of pathogenic microorganisms in meat and meat products. Furthermore, APCP treatment can be used to generate nitrite, which is an essential component of the curing process. Here, we introduce the effectiveness of APCP treatment as a pasteurization method and/or curing process for use in the meat and meat product processing industry.
Magnetic Tagging of Therapeutic Cells for MRI

Transplantation of stem cells or immune cells has shown promise for the treatment of several diseases. Monitoring magnetically labeled cells with MRI has furthered our understanding of cellular migration and the pathophysiology of diseases in experimental models. These studies should pave the way for guiding clinical trials using cell-based therapies. This review briefly describes the various methods used to label and track cells with MRI and the potential for such methods to translate to human applications.
A distributed interference-aware rank adaptation algorithm for local area MIMO systems with MMSE receivers

Typically, rank adaptation (RA) algorithms are aimed at balancing the trade-off between increasing the spatial gain and improving the interference resilience property. In this paper, we consider a small-cell/local area cellular system and propose a simple and distributed interference-aware rank adaptation algorithm aimed at maximizing the system sum throughput. The performance of the proposed algorithm is numerically evaluated in terms of the system sum throughput. Simulation results show that the proposed algorithm results in close to optimum throughput performance, and can provide up to 40% throughput gain over interference-unaware RA schemes.
Clinical significance of plasma chlorpromazine levels I. Plasma levels of the drug, some of its metabolites and prolactin during acute treatment

Synopsis Seventeen acute psychotic patients were studied in the course of chlorpromazine (CPZ) treatment. Blood samples were taken weekly both before and two hours after the morning CPZ dose. Plasma levels of CPZ, CPZ sulphoxide (CPZSO) monodesmethylated CPZ (NOR1CPZ) and 7-hydroxy CPZ (7OH CPZ) were estimated by gas chromatography. Plasma prolactin, luteinizing hormone, testosterone and oestrogens were measured by radioimmunoassay. Six of the seven patients who showed no clinical improvement had plasma CPZ levels equal to or higher than those of patients who improved. ‘Non-responders’ had a greater proportion of CPZ SO in pre-dosage samples. The occurrence of parkinsonian side effects was associated with a mean plasma CPZ of > 50 ng/ml and a mean plasma prolactin of > 30 ng/ml two hours after dosage. The elevation of prolactin preceded the onset of parkinsonian symptoms by 1–2 weeks. There was a significant positive correlation between mean plasma prolactin and mean plasma CPZ levels. The prolactin response may prove a useful index of the central antidopaminergic effect of neuroleptic drugs.
Preservation of the eye in paranasal sinus cancer surgery.

To the Editor . —It is always interesting to read articles where the author's experience differs radically from one's own. "Preservation of the Eye in Paranasal Sinus Cancer Surgery," 1 at first reading, appears to be such an article, for, in my personal series of 234 maxillary and ethmoidal sinus malignancies, orbital clearance was needed in 26% of patients. However, the article by Perry et al should surely be entitled, "Preservation of the Eye in Surgery for Esthesioneuroblastoma," for this tumor, not common in the maxillary sinus, made up 21% of their total experience. In my series, 15 olfactory tumors represented only 6% of the total experience. Indeed, squamous carcinoma of the maxillary sinus is by far the most common site and malignancy affecting the paranasal sinuses. I have only had to remove orbital contents once when treating olfactory tumors by craniofacial resection 2 and local resection of small portions of
Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis

The role of the circadian clock in skin and the identity of genes participating in its chronobiology remain largely unknown, leading us to define the circadian transcriptome of mouse skin at two different stages of the hair cycle, telogen and anagen. The circadian transcriptomes of telogen and anagen skin are largely distinct, with the former dominated by genes involved in cell proliferation and metabolism. The expression of many metabolic genes is antiphasic to cell cycle-related genes, the former peaking during the day and the latter at night. Consistently, accumulation of reactive oxygen species, a byproduct of oxidative phosphorylation, and S-phase are antiphasic to each other in telogen skin. Furthermore, the circadian variation in S-phase is controlled by BMAL1 intrinsic to keratinocytes, because keratinocyte-specific deletion of Bmal1 obliterates time-of-day–dependent synchronicity of cell division in the epidermis leading to a constitutively elevated cell proliferation. In agreement with higher cellular susceptibility to UV-induced DNA damage during S-phase, we found that mice are most sensitive to UVB-induced DNA damage in the epidermis at night. Because in the human epidermis maximum numbers of keratinocytes go through S-phase in the late afternoon, we speculate that in humans the circadian clock imposes regulation of epidermal cell proliferation so that skin is at a particularly vulnerable stage during times of maximum UV exposure, thus contributing to the high incidence of human skin cancers.
The impact of work-life connectivity on professional women: A case study of telecom industry

The purpose of this research was to test work life border theory against job/life satisfaction. The impact of work-life connectivity on professional women working in telecom industry was checked. This quantitative research was conducted by collecting secondary data gathered through world recognized questionnaires. A sample size of 285 respondents was collected through Qualtrics and self-administered questionnaires. This sample was adequate as using Power and Precision software a minimum sample of 175 was computed. Cluster sampling technique in combination with stratified sampling was used to collect data from women in Telecom Industry from major cities of Pakistan. Data collected was analyzed in SPSS and SEM was run on AMOS. Pearson r correlation and regression tests were run to study the effect of the understudy variables. The study found that both types of connectivity, work- to- family and family- to-work directly influence job and family satisfaction of women. The results suggest that family-friendly policies and organizational support can bring substantial benefits to women workers and the organization as a whole. https://doi.org/10.34105/j.kmel. 2016.08. 019
Deliberations on the development of an intercultural competence curriculum

Committed to developing an institution-wide intercultural competence curriculum for master’s-level students preparing for international careers, a team of nine professors from across disciplines deliberated for a year on their fundamental understandings of intercultural competence and what it would mean to facilitate the development of that competence in students. This article recounts the team’s philosophical debates related to intercultural competence: definitions, effective methods of teaching, intersectionality of identities, Western bias in the literature, power and inequity, and the role of language learning. The deliberations became the foundation for an institution-wide curriculum, focused on helping graduates to be not only effective workers and managers in multicultural settings, but also to be leaders in social change. This article shares the conversations and considerations of the planning process and the breadth and emphasis of the curriculum that emerged. Reflections on students’ learning and recommendations for curriculum developers are offered.
Selective Extraction of Gardenia Yellow and Geniposide from Gardenia jasminoides by Mechanochemistry

A novel method for the selective extraction of gardenia yellow and geniposide from Gardenia Jasminoides, based on a mechanochemical method is described. Without the need of complex separation techniques, gardenia yellow compliant with the national standard could be extracted in a simple fashion. The optimal ball-milling conditions determined were as follows: 30% g/g. active carbon milling at 200 rpm in a planetary mill for 5 min. The extraction conditions of the milled mixtures were as follows: the milled mixtures were extracted with water (liquid-solid ratio 10:1) at 20 °C for 5 min with yields 85% of total geniposide, followed by extraction with 80% ethanol solution (liquid-solid ratio 5:1) and 1% g/g. Tween 20 at 75 °C for 5 min to yield 1.45% ± 0.108% g/g of gardenia yellow. The mechanism of this selective extraction was demonstrated to follow a microstructure change of activated carbon, which occurred during milling and lead to alteration of the corresponding desorption capacities. Compared with traditional extraction methods, this novel extraction technique greatly simplifies the separation process, and proves to be advantageous in terms of low organic solvent consumption, easy operation, rapid process and high efficiency.
Rituals of care for the elderly in northern Thailand: Merit, morality, and the everyday of long‐term care

Caregivers’ quotidian actions challenge prevailing views of care that rely on the emotional or attentive orientation of the caregiver. The routinized care tasks provided by two middle-aged women for their bedridden mother in northern Thailand reveal the realities of long-term caregiving. For these sisters, care transforms “merit” and “karma” without reliance on internal conviction. This context in turn reflects how people enact values and maintain social worlds through habituated physical practices of providing for others. Ordinary care in practice—termed “rituals of care”—dislodges fixation on particular personal sentiments and affirms the study of care as a powerful tool for assessing enduring modes of moral experience as well as subtle forms of social change. [care, ritual, phenomenology, Buddhism, Thailand, embodiment, morality]
A New Expectation-Maximization Statistical Test for Case-Control Association Studies Considering Rare Variants Obtained by High-Throughput Sequencing

Genome-wide association studies (GWAS) have been successful in identifying common genetic variation reproducibly associated with disease. However, most associated variants confer very small risk and after meta-analysis of large cohorts a large fraction of expected heritability still remains unexplained. A possible explanation is that rare variants currently undetected by GWAS with SNP arrays could contribute a large fraction of risk when present in cases. This concept has spurred great interest in exploring the role of rare variants in disease. As the cost of sequencing continue to plummet, it is becoming feasible to directly sequence case-control samples for testing disease association including rare variants. We have developed a test statistic that allows for association testing among cases and controls using data directly from sequencing reads. In addition, our method allows for random errors in reads. We determine the probability of a true genotype call based on the observed base pair reads using the expectation-maximization algorithm. We apply the SumStat procedure to obtain a single statistic for a group of multiple rare variant loci. We document the validity of our method through simulations. Our results suggest that our statistic maintains the correct type I error rate, even in the presence of differential misclassification for sequence reads, and that it has good power under a number of scenarios. Finally, our SumStat results show power at least as good as the maximum single locus results.
Abnormal metabolic network activity in REM sleep behavior disorder

Objective: To determine whether the Parkinson disease–related covariance pattern (PDRP) expression is abnormally increased in idiopathic REM sleep behavior disorder (RBD) and whether increased baseline activity is associated with greater individual risk of subsequent phenoconversion. Methods: For this cohort study, we recruited 2 groups of RBD and control subjects. Cohort 1 comprised 10 subjects with RBD (63.5 ± 9.4 years old) and 10 healthy volunteers (62.7 ± 8.6 years old) who underwent resting-state metabolic brain imaging with 18F-fluorodeoxyglucose PET. Cohort 2 comprised 17 subjects with RBD (68.9 ± 4.8 years old) and 17 healthy volunteers (66.6 ± 6.0 years old) who underwent resting brain perfusion imaging with ethylcysteinate dimer SPECT. The latter group was followed clinically for 4.6 ± 2.5 years by investigators blinded to the imaging results. PDRP expression was measured in both RBD groups and compared with corresponding control values. Results: PDRP expression was elevated in both groups of subjects with RBD (cohort 1: p < 0.04; cohort 2: p < 0.005). Of the 17 subjects with long-term follow-up, 8 were diagnosed with Parkinson disease or dementia with Lewy bodies; the others did not phenoconvert. For individual subjects with RBD, final phenoconversion status was predicted using a logistical regression model based on PDRP expression and subject age at the time of imaging (r2 = 0.64, p < 0.0001). Conclusions: Latent network abnormalities in subjects with idiopathic RBD are associated with a greater likelihood of subsequent phenoconversion to a progressive neurodegenerative syndrome.
A Clinical Report of Bone Regeneration in Maxillofacial Surgery using Bonelike ® Synthetic Bone Graft

The objective of this study is to evaluate the osteoconductivity and bioactivity of the Bonelike® graft in repairing surgical cystic bone defects. Bonelike® is implanted in 11 patients, aged between 24 and 53 years with a mean age of 36 years, consisting of 5 men and 6 women. According to the standard follow up protocols, radiological examinations are performed and Bonelike®/bone retrieved samples have been analyzed histologically using non-decalcified sections obtained perpendicular to bone length axis. Radiographic examination and histological results clearly demonstrate an extensive new bone formation apposed on Bonelike® granules with a significant degree of maturation. These clinical applications in maxillary bone defects indicate perfect bone bonding between new bone formed and Bonelike ® granules, along with partial surface biodegradation. This quick and effective osteoconductive response from Bonelike® may reduce the time needed to reconstruct the bone defected area of patients.
Pattern of Neurogenesis and Identification of Neuronal Progenitor Subtypes during Pallial Development in Xenopus laevis

The complexity of the pallium during evolution has increased dramatically in many different respects. The highest level of complexity is found in mammals, where most of the pallium (cortex) shows a layered organization and neurons are generated during development following an inside-out order, a sequence not observed in other amniotes (birds and reptiles). Species-differences may be related to major neurogenetic events, from the neural progenitors that divide and produce all pallial cells. In mammals, two main types of precursors have been described, primary precursor cells in the ventricular zone (vz; also called radial glial cells or apical progenitors) and secondary precursor cells (called basal or intermediate progenitors) separated from the ventricle surface. Previous studies suggested that pallial neurogenetic cells, and especially the intermediate progenitors, evolved independently in mammalian and sauropsid lineages. In the present study, we examined pallial neurogenesis in the amphibian Xenopus laevis, a representative species of the only group of tetrapods that are anamniotes. The pattern of pallial proliferation during embryonic and larval development was studied, together with a multiple immunohistochemical analysis of putative progenitor cells. We found that there are two phases of progenitor divisions in the developing pallium that, following the radial unit concept from the ventricle to the mantle, finally result in an outside-in order of mature neurons, what seems to be the primitive condition of vertebrates. Gene expressions of key transcription factors that characterize radial glial cells in the vz were demonstrated in Xenopus. In addition, although mitotic cells were corroborated outside the vz, the expression pattern of markers for intermediate progenitors differed from mammals.
Neural correlates of eye tracking deficits in first-degree relatives of schizophrenic patients: a positron emission tomography study.

BACKGROUND Schizophrenia is thought to arise from the interaction of genetically mediated and environmentally triggered abnormalities in brain function. Reduced frontal activation, reported in schizophrenic patients, may be one expression of genetic risk. The present study investigated whether frontal activation in relatives of schizophrenic patients would be related to eye tracking deficits (ETD), which are considered a behavioral marker of risk for schizophrenia. METHODS Subjects were first-degree relatives of schizophrenic patients (n = 17) and controls (n = 11). Relatives were divided into those with normal and abnormal pursuit based on qualitative ratings. Subjects were scanned using positron emission tomography and the H(2)15O bolus subtraction technique while performing smooth pursuit and fixation. Brain areas more active in pursuit than fixation were identified in the 3 groups. Correlations were used to investigate the relationship between activation of pursuit regions and pursuit gain in the relatives. RESULTS Controls significantly activated frontal eye fields (FEFs) and posterior areas, including the motion processing area, V5, and cuneus. The 2 groups of relatives activated the same posterior regions as controls, but differed from each other in activation of FEFs. Relatives with normal tracking activated right dorsal FEFs while relatives with ETD did not. Individual subtractions revealed that 90% of controls and 100% of the relatives with normal tracking activated FEFs during pursuit compared with 42% of relatives with ETD (P = .009). Pursuit gain was significantly and selectively associated with percent activation of right dorsal FEFs (r = 0.74). CONCLUSIONS Subtle frontal dysfunction seems to be a pathophysiological substrate of ETD in relatives of schizophrenic patients, and may be one aspect of genetically mediated differences in brain function relevant to schizophrenia.
Big-data-generated traffic flow prediction using deep learning and dempster-shafer theory

This work addresses short-term traffic flow prediction by proposing a big-data-based framework. The proposed framework uses data fusion to deal with heterogeneous data generated from various sources. The data are categorized into two types: streams of data and event-based data. In this work, Deep Belief Networks (DBNs) are used to independently predict traffic flow using streams of data, i.e., historical traffic flow and weather data, and event-based data, i.e., tweets. Furthermore, Dempster's conditional rule for updating belief is used to fuse evidence coming from streams of data and event-based data modules to achieve enhanced prediction. The experimental results using real-world data show the merit of the proposed framework compared to the state-of-the-art ones.
Stability analysis of T-S fuzzy PD, PI, and PID control systems

We present a simple and systematic way of designing stabilization fuzzy PID (Proportional-Integral-Differential), PI (Proportional-Integral), and PD (Proportional-Differential) controllers for the T-S fuzzy model. The state space representations of the fuzzy PD, PI, and PID controllers are firstly presented. Then we equivalently transform the fuzzy PID (PI, or PD) control system into the fuzzy static output feedback control system. The fuzzy static output feedback controller design for the latter system can be efficiently solved via the existing numerical optimization methods with some conservatism. Consequently, the fuzzy PID (PI, or PD) controller can be derived due to the one-on-one correspondence between the fuzzy PID controller and the fuzzy static output feedback controller. We use a numerical simulation example to show the effectiveness of our proposed methods.
Time-Offset Injection Method for Neutral-Point AC Ripple Voltage Reduction in a Three-Level Inverter

The purpose of neutral-point voltage balancing algorithms in the three-level neutral-point clamped (3L-NPC) topology is to eliminate the voltage unbalance of top- and bottom-side dc-link voltages (neutral-point voltage). These algorithms are divided into dc unbalance and ac unbalance compensation methods. The dc unbalance causes distortion of output currents; therefore, this problem has to be solved. The ac unbalance implies that there is an ac ripple in the top- and bottom-side dc-link voltages. In applications using 3L-NPC topology, a large dc-link capacitor value is required to mitigate this ac unbalance problem. As a result, the size and the cost of applications become large and expensive. In this paper, a compensation method for mitigating the ac unbalance of the neutral-point voltage is proposed, which causes the dc-link capacitor value to be small, when a carrier-based pulse width modulation method is applied. The proposed method compensates the ac unbalance of the neutral-point voltage by adding an optimal compensation value to the reference duty signals. This compensation value is calculated simply by currents and reference duty signals. The calculation process of the optimal compensation value is discussed, and the effectiveness of the proposed method is verified with simulations and experiments.
Unconventionality and Originality: Does Self-Assessed Unconventionality Increase Original Achievement?

Creativity is negatively associated with certain personality traits (e.g., conformity) and social influences (e.g., group pressure). In this study, creativity was examined in relation to unconventionality, which was expected to correlate positively with creativity, especially originality. This hypothesis was based on the theory that unconventional people hold uncommon views and attitudes and develop more diverging concepts and associations, which build the foundation for creative thinking. To examine the hypothesis, an online study with N = 90 participants was conducted. Unconventionality was measured with a new self-rating questionnaire, and creativity was measured with unusual uses, consequences, and explanations measures, which assessed both originality (rarity and uniqueness) and flexibility (diversity). The association of unconventionality with originality, after controlling for flexibility, was compared to other constructs (openness, conservatism, education). Path analysis revealed strong effects of unconventionality on originality (latent β = .58, r = .64). Unconventionality continued to predict originality after controlling for openness, which was weakly related to originality (β = .08, r = .49). Unconventionality weakly predicted flexibility (β = .09, r = .26). Supplemental analyses indicated that the effects of unconventionality on originality were not attributable to confounds (e.g., conservatism or education). The results indicate that the effects of unconventionality are positive, specific, substantial, and independent of related constructs (e.g., openness).