Miracle-dz/UniFAR-FTUs huggingface dataset:
Experimental study of a novel thermotherapy for hepatocellular carcinoma using a magnesium ferrite complex powder that produces heat under a magnetic field.

BACKGROUND/AIMS The anti-cancerous effect on hepatocellular carcinoma of a newly established form of thermotherapy, which uses an implant heating system, was evaluated. As a new material for application in hyperthermia, the authors developed a powder type Mg-ferrite complex that produces heat under a relatively low-power magnetic field. METHODOLOGY This material suspended in Lipiodol was injected into tumors on the backs of mice that consisted of human hepatocellular carcinoma cells. Hyperthermia was performed by directing a magnetic charge on tumor-bearing mice that contained the Mg-ferrite complex. The temperature of the tumor was kept at 42-43 degrees C, while the magnetic field power ranged from 50 to 80G. RESULTS A 10-min hyperthermia treatment was insufficiently effective against tumor growth. Systemic injection of doxorubicin (ADM) before hyperthermia appeared to enhance the anti-cancerous effect, but the difference was little and did not reach a statistically significant level (repeated measure analysis of variance). The anticancerous effect of hyperthermia for 15 minutes, in contrast, was marked. The nodules had almost completely disappeared by the end of the experiment. CONCLUSIONS In conclusion, it is suggested that hyperthermotherapy using this newly developed Mg-ferrite complex might become an option for low-invasive therapy for advanced hepatocellular carcinoma in humans.
A New RP Selection Algorithm Based on Delay in DiffServ Networks

Rendezvous point (RP) selection is a critical problem in PIM-SM multicast routing protocol, which influences the performance of the multicast tree. Currently most protocols use manual operation to do RP selection. But the selected RP may not be the best one, thus leading to congestions and delays unavoidably. What we want to achieve is that the best node can be selected as RP automatically and reselected dynamically when the group members change. In this paper, we use PIM-SM multicast routing protocol on the Diffserv network and evaluate the total cost of the shared tree with delay. We propose a new RP selection and a reselection algorithm when the multicast group members join and leave dynamically. Simulation shows that our new algorithms have better performance than the conventional one because the total cost of the shared tree is reduced evidently.
Exploring Trust as an Influencing Mechanism of Intrapreneurship

Managers and employees in four diverse organization settings were interviewed with semi-structured methods to provide grounded insight about the potential role of trust as a contributor to intrapreneurial behavior. The data suggest that several different dimensions of trust influence intrapreneurial behavior. Transcription analysis identified dimensions of trust as “downward trust-in,” “upward trust-of,” and “upward trust-in. ” In addition, lateral trust, reciprocity and the cascading effects of managerial trust, are explored. Study results are examined within the theory of intrapreneurship in organizations and directions for future research are outlined.
Quantitative diffusion-tensor tractography of long association tracts in patients with traumatic brain injury without associated findings at routine MR imaging.

PURPOSE To evaluate whether quantitative diffusion-tensor tractography can show abnormalities in long association tracts of subjects with symptoms after traumatic brain injury without any visible signs of intracranial or intraparenchymal abnormalities of obvious traumatic origin at routine magnetic resonance (MR) imaging and to determine the number and type of these abnormalities. MATERIALS AND METHODS The study was approved by the local ethics committee, and informed consent was obtained from all subjects. Diffusion-tensor tractography was performed at 3.0 T in 106 consecutive clinical patients with traumatic brain injury without abnormalities at conventional MR imaging (age, 16-56 years) and 62 age- and sex-matched control subjects. Volume, mean apparent diffusion coefficient (ADC), and mean fractional anisotropy (FA) were measured in the following tracts: uncinate fasciculus, superior cingulum, temporal cingulum, superior longitudinal fasciculus, arcuate fasciculus, inferior fronto-occipital fasciculus, and inferior longitudinal fasciculus. Statistical analyses were based on repeated-measures analysis of covariance. RESULTS In control subjects, tract volumes showed large variability whereas FA and ADC showed small variability. In several tracts, mean FA values correlated negatively with the respective volumes. In patients with brain injury, FA values were reduced in both uncinate fasciculi, both inferior fronto-occipital fasciculi, and in the right inferior longitudinal fasciculus compared with control subjects (P < .05). Diffusivity was increased in half of the tracts (P < .05). The tract volumes were not significantly reduced. CONCLUSION Quantitative diffusion-tensor tractography is able to show posttraumatic FA and ADC abnormalities in patients with normal findings at conventional MR imaging in several association tracts, most commonly the uncinate fasciculus. SUPPLEMENTAL MATERIAL http://radiology.rsna. org/lookup/suppl/doi:10.1148/radiol.12112570/-/DC1.
Psychopathology and Parenting Practices of Parents of Preschool Children With Behavior Problems

Objective . This study investigated associations among different types of parental psychopathology and several specific parenting practices. Design . Mothers (n = 182) and fathers (n = 126) of preschool-aged children with behavior problems completed questionnaires assessing parental psychopathology and parenting practices and participated in observed parent–child interactions. Results . Maternal depression, anxiety, substance abuse, and several different personality disorder traits were related to maternal negativity, laxness, and lack of warmth. Paranoid, schizoid, schizotypal, and borderline personality disorder symptoms predicted mothers' parenting practices, even when statistically controlling for other types of psychopathology. For fathers, those same symptoms, dependent and avoidant symptoms, and substance abuse symptoms were associated with self-reported lax parenting. Some evidence emerged that psychopathology in one parent was associated with less overreactivity in the other. Conclusions . Many aspects of parents' psychological functioning play a role in determining specific parenting practices, including personality disorder symptoms.
MENTAL MORBIDITY AMONG GRADUATE AND RESEARCH STUDENTS : AN EPIDEMIOLOGICAL STUDY

SUMMARY A cross sectional epidemiological study of mental morbidity among 1160 postgraduate and research students was done by census method. Goldberg's 60 item GHQ was used as screening tool and a person scoring 12 and above was taken as a case. The response rate was 92.5%. A prevalence rate of 16.63 was found. The relationship between mental morbidity and selected socio-demographic, motivational psychological variables; certain life experiences in the campus was studied. The results are discussed. This study is first of its kind in our country.
Internationalization of emerging market firms: the case of Turkish retailers

Purpose – The purpose of this paper is to understand the internationalization process (IP) of retailing firms from emerging markets and to determine a new focus and/or modifications if necessary in the established Western‐based theories.Design/methodology/approach – The paper follows an exploratory approach utilizing qualitative multiple case studies. Data are collected through eight in‐depth interviews with senior managers of four Turkish retail firms in textile and ready‐to‐wear industry. An inductive approach is followed.Findings – It is found that internal drivers, home and host country characteristics and matching have an impact on the IP of retail firms from emerging markets. A table is formed to compare and contrast IP in the context of developed country, emerging market, and Turkish retail firms. Also a model is proposed to understand the IP of Turkish retail firms.Research limitations/implications – The proposed model of IP for Turkish retail firms provides an initial point for building theory in.
Pricing Contingent Convertible Bond with Idiosyncratic Risk

Under an incomplete market, we develop a utility-based pricing model for equity and contingent convertible bond (CCB) while the straight bond is priced by an equilibrium pricing method. We derive the semi-closed-form solutions of the utility-based prices of equity and CCB and the explicit equilibrium prices of all securities. We find that the increased firm value due to CCB increases dramatically with idiosyncratic risk volatility and risk aversion index. The firm value is a concave function of conversion ratio of CCB and there is a unique global maximum point. The optimal conversion ratio increases with the risk aversion index. If investors are risk-averse enough, as idiosyncratic risk rises, the optimal capital structure includes less CCB and equity but more straight bond. However, if investors are risk-neutral, the opposite holds true. In general, there are risk-taking incentives for risk-neutral investor but on the contrary, there are not even if investor is somewhat risk-averse. The higher the conversion ratio of CCB or the larger the risk aversion index, the weaker the risk-taking incentives but there is no obvious evidence on whether CCB will further decrease the risk-taking incentives.
Multi-View Ontology Explorer (MOE): Interactive Visual Exploration of Ontologies

An ontology is an explicit specification of a conceptualization. This specification consists of a common vocabulary and information structure of a domain. Ontologies have applications in many fields to semantically link information in a standardized manner. In these fields, it is often crucial for both expert and non-expert users to quickly grasp the contents of an ontology; and to achieve this, many ontology tools implement visualization components. There are many past works on ontology visualization, and most of these tools are adapted from tree and graph based visualization techniques (e.g. treemaps, node-link graphs, and 3D interfaces). However, due to the enormous size of ontologies, these existing tools have their own shortcomings when dealing information overload, usually resulting in clutter and occlusion on the screen. In this thesis, we propose a set of novel visualizations and interactions to visualize very large ontologies. We design 5 dynamically linked visualizations that focus on a different level of abstraction individually. These different levels of abstraction start from a high-level overview down to a low-level entity. In addition, these visualizations collectively visualize landmarks, routes, and survey knowledge to support the formation of mental models. Search and save features are implemented to support ondemand and guided exploration. Finally, we implement our design as a web application.
Numerical approximation and analysis of mathematical models arising in cells movement

The Phd thesis is devoted to the numerical and mathematical analysis of systems of partial differential equations arising in the modeling of cells movement. The model of nutrient-dependent tumour growth is built and the asymptotic stability of constant steady states for small perturbations is proved. Then the parabolic and hyperbolic models of chemotaxis are approximated using finite differences and finite volume methods. In particular, a consistent scheme, which is well-balanced on steady states with constant velocity, preserves the non negativity of the density and treats the vacuum, is constructed. Having efficient and accurate numerical methods the behaviour of the solutions is analyzed. At first the pure diffusion problem, for which the waiting time phenomenon and regularity under the physical boundary condition are of main concern. Then the attention is focused on the study of existence and stability of non constant stationary solutions and long time behaviour of the hyperbolic model of chemotaxis on a bounded domain.
Do relationships with multinational buyers improve the marketing capabilities of suppliers in transition economies

Transition economies are characterized by a move away from central-planning towards open markets and increased competition. During the transformation process, managers face pressure to adapt to competition and to acquire the skills of marketing – the ability to meet customer needs more effectively than rivals. Consequently, an important question to be asked is: what factors affect the ability of a transition economy manager to learn the skills or capabilities of marketing? Past research on this subject tends to be limited to those relatively rare transition economy firms that are directly linked with foreign firms, either through joint ventures or export exchanges. However, the focus of analysis in this study is defined in terms of supply-relationships linking indigenous suppliers with multinational buyers domiciled within transition economies. In contrast with studies examining the marketing capabilities of transition economy-exporters, this study examines transition economy firms whose main business is limited to the domestic market. The premise of this study is that exchange relationships with multinational buyers can serve as conduits for the transfer of marketing capabilities. If so, the absence of joint venture participation or export exchanges need not be a barrier to learning the skills of marketing. Building on research investigating buyer-seller relationships, organizational learning, and marketing capabilities, several hypotheses are developed in this study.
Study on evaluation of emergency plans

To effectively evaluate the emergency plans is the key link to improve the effectiveness of emergency plans and ensure to play the desired effect of emergency plans. At present,the evaluation on emergency plans in China is mostly template evaluation,and the basis and the content of evaluation remain to be improved. The application of contrast method in evaluation of emergency plans was discussed. Taking improving the emergency preparedness ability as purpose,the emphasis of evaluation was put on five aspects of emergency plans,including the adequacy,feasibility,completeness,acceptability and compliance,and the revision suggestions of emergency plan were put forward. The evaluation process was described in detail by taking a real emergency plan as example.
Impact of Ride-Sourcing Services on Travel Habits and Transportation Planning

The use of app-based, on-demand ride-sourcing services has spread rapidly and become more and more important in urban transport. Companies such as Uber and Lyft may provide better service with less waiting time and higher vehicle occupancy when compared to traditional transportation services such as private auto, public transit and taxis. This new type of transportation service is defined as ride-sourcing. This increase in the ride-sourcing availability, due to the introduction of Uber and Lyft, may impact travel habits and change the local, regional and national travel demand. The research compared the users’ differences in travel characteristics between traditional transportation services and new ride-sourcing services. This comparison was be done by conducting a survey in the Pittsburgh region to determine users’ attitude and travel habits when using ride-sourcing services. The results of the survey were used to compare to the travel characteristics of ride-source users to established travel behavior data and then determine how the impact of ride-sourcing on travel habits may be incorporated into the transportation planning process. The findings indicate that ride-sourcing users are generally younger than the typical traveler, the service is used by a higher percentage of males and females. Social and recreational trips are the predominant type of trips used for ride-sourcing followed by work trips, trip lengths are shorter for all types of trips when compared to typical trip makers and vehicle occupancy rates are generally higher for ride-sourcing trips. Ride sourcing users generate more trips than typical traveler’s in the Pittsburgh region and the use of taxis and private autos are most impacted by ride sourcing where users’ shift away from these modes. Currently, ride-sourcing is still a relatively small number of daily trips in an urban area. However as populations increase in urban areas and the demand for transportation facilities increases the new type of travel could increase to significant levels. It could be considered as a new transportation mode or categorized in as an auto mode in travel demand models.
Can we ever stop imaging in surgically treated and radiotherapy-naive patients with non-functioning pituitary adenoma?

BACKGROUND Non-functioning pituitary adenomas (NFAs) are slow-growing tumours with reported re-growth rates following surgical resection alone of up to 50% at 10 years. Currently, the desired length of follow-up surveillance imaging in un-irradiated patients is unclear. AIM To clarify the timing of re-growth in patients with NFAs, treated solely by surgery without post-operative pituitary radiotherapy, and also to clarify whether continued imaging is necessary in these patients. METHODS A case note analysis of all patients who underwent surgery alone for NFA between January 1984 and December 2007 was undertaken. Patients were followed for a minimum of 1 year. Re-growth was diagnosed on the basis of radiological appearances with or without associated manifestations. RESULTS One hundred and fifty-five patients (94 males, mean age at diagnosis 57.9 (range 18.3-88) years) were included. Twenty-nine were followed up for more than 10 years. The mean follow-up following surgery was 6.1 years (median 4.3 (range 1-25.8)). Re-growth was documented in 54 (34.8%) cases and 20.4% of these cases showed relapse/re-growth 10 or more years after the initial surgery. Kaplan-Meier analysis showed relapse rates of 23.1, 46.7 and 67.9% at 5, 10 and 15 years respectively. There was a significant increase in the re-growth rates if there was either pituitary tumour remnant observed on the first post-operative scan (P≤0.001) or a younger age at initial surgery (P=0.034). CONCLUSION These results suggest that patients with NFAs need to be closely monitored following surgery, particularly those with post-operative tumour remnants. With 20% of relapse occurring after 10 years, follow-up surveillance needs to be continued beyond this time.
Modeling of capacitive and electromagnetic field shielding effects in a CVT

In the discharge of a capacitor the current was measured with a current viewing transformer (CVT). In addition to measuring the current flowing through the CVT primary, a 51 MHz noise signal was added to the primary current. When the CVT was covered with a gold shield, the noise was eliminated. Analysis of the measured results indicate that the gold layer reflected the electromagnetic that was generated by current flowing in the primary and that the capacitance between the shield and the CVT secondary had no measurable effect on the CVT output
Traffic classification using probabilistic neural networks

Traffic classification, a branch of passive network measurement, becomes more and more important for network management. As traditional traffic classification techniques like port-based and payload-based techniques become ineffective for complicated internet applications which use dynamic port number and encryption techniques to avoid detection, machine learning based techniques gained more and more attentions in the past few years. But there are few studies that focus on applying neural computation techniques for traffic classification. In this paper, we use a distributed host based traffic collection platform (DHTCP) to gather traffic samples with accurate application information on user hosts. Then probabilistic neural network was used to traffic classification. Web and P2P traffics were studied since they are the most predominant internet traffic types. experimental results show that probabilistic neural network is an effective machine learning technique for traffic identification
Polyethylenimine-mediated cochlear gene transfer in guinea pigs.

OBJECTIVE To demonstrate and compare polycationic-mediated cochlear gene transfer with linear polyethylenimine (PEI) via cochleostomy and osmotic pump infusion method. DESIGN A dissociated cochlear culture was used to select the optimum nitrogen to phosphate ratio of PEI/DNA complexes to be used in vivo. The PEI-enhanced green fluorescent protein reporter gene DNA complex was introduced with single inoculation (cochleostomy) or with sustained delivery (osmotic pump method) into guinea pig cochleas and examined for transgene expression. SUBJECTS Male Albino Hartley guinea pigs (250-350 g). RESULTS The relatively low transfection efficiency of PEI limits its potential when compared with viral counterparts; however, sustained release of the vector solution was able to improve PEI's transfection efficiency. The PEI-infused cochleas maintained intact cellular and tissue architecture with absence of inflammation. Transfection confined to the perilymphatic space highlights the need to target the gene vector into the scala media if transfection is targeted at cells within the organ of Corti. CONCLUSION These findings indicate that PEI is able to transfect the cochlea in vivo with sustained delivery and present an alternative for nonviral cochlear gene therapy.
False-Positive Results in a Recombinant Severe Acute Respiratory Syndrome-Associated Coronavirus (SARS-CoV) Nucleocapsid Enzyme-Linked Immunosorbent Assay Due to HCoV-OC43 and HCoV-229E Rectified by Western Blotting with Recombinant SARS-CoV Spike Polypeptide

ABSTRACT Using paired serum samples obtained from patients with illness associated with increases in anti-human coronavirus OC43 (HCoV-OC43) or anti-HCoV-229E antibodies, we examined the possibility of false-positive results detected in a recombinant severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) nucleocapsid protein immunoglobulin G enzyme-linked immunosorbent assay (ELISA). Three of the 21 and 1 of the 7 convalescent-phase serum samples from persons with increases in antibodies against HCoV-OC43 and HCoV-229E, respectively, tested positive by the recombinant SARS-CoV nucleocapsid protein-based ELISA. None of these samples were found to contain a specific antibody in the recombinant SARS-CoV spike polypeptide-based Western blot assay.