Miracle-dz/UniFAR-FTUs huggingface dataset:
Liminality and Low-Income Aging Families by Choice: Meanings of Family and Support*

RÉSUMÉ Le vieillissement, à travers la lentille de l'individualisation, démontre des changements, tant dans la composition de la famille et le sens de la famille et du soutien. Les familles à faible revenu qui – pour survivre – aussi choisissent parfois de nouvelles relations flexibles de soutien social, y compris les parents et non-parents : celles sont les familles vieillissantes par choix. En appliquant le concept de liminalité (états transitoires de l’être), créé par l’individualisation, nous avons exploré les expériences de liens étroits dans les familles à faible revenu constitutées de parents et membres non-parents vieillissants. Des entretiens qualitatifs avec des répondants représentant deux ou trois générations de familles vieillissantes par choix ont montré comment ces familles perçoivent les sens de la famille et du soutien social. Nous trouvons que la reciprocité est moins essentielle aux rapports entre les plus vieux et les plus jeunes dans les réseaux familiaux que l’on pourrait s’attendre. La liminalité façonne les sens et les échanges dans les familles vieillissantes à faible revenu par choix, de sorte que n’importe la façon dont les relations soient-elles ténues, elles procurent un sentiment d’appartenance et de la signification. ABSTRACT Through the lens of individualization, aging families demonstrate changes both in family composition and in meanings of family and support. So, also, do low-income families that – in order to survive – choose flexible, sometimes novel, social-support relations, including kin and non-kin: these are aging families by choice. Applying the concept of liminality (transitional states of being) created through individualization, we explored the experiences of close relations in low-income families consisting of aging kin and non-kin members. Qualitative interviews with respondents representing two or three generations of aging families of choice illustrated how these families perceive the meanings of family and social support. We find that reciprocity is less vital to relationships of older with younger members in familial networks than may be expected. Liminality contours meanings and exchanges in low-income aging families of choice such that no matter how tenuous relations may be, they provide a sense of belonging and meaning.
Formation of Polyomavirus-Like Particles with Different VP1 Molecules That Bind the Urokinase Plasminogen Activator Receptor

ABSTRACT Icosahedral virus-like particles formed by the self-assembly of polyomavirus capsid proteins (Py-VLPs) can serve as useful nanostructures for delivering nucleic acids, proteins, and pharmaceuticals into animal cells and tissues. Four predominant surface-exposed loops in the VP1 structure offer potential sites to display sequences that might contribute new targeting specificities. Introduction into each of these loops of sequences derived from the amino-terminal fragment of urokinase plasminogen activator (uPA) or a related phage display peptide reduced the solubility of VP1 molecules when expressed in insect cells, and insertions into the EF loop reduced VP1 solubility least. Coexpression in insect cells of the uPA-VP1 molecules and VP1 containing a FLAG epitope in the HI loop permitted the formation of heterotypic Py-VLPs containing uPA-VP1 and FLAG-VP1. These heterotypic VLPs bound to uPAR on the surfaces of animal cells. Heterotypic Py-VLPs containing ligands for multiple cell surface receptors should be useful for targeting specific cells and tissues.
A Typology of Knowledge Management System Use by Teams

This essay sketches out a typology of knowledge management system use by teams. It is proposed that how a knowledge management system is framed and enacted by a team depends on (a) psychological safety (the shared beliefs held by members of a team that the team is safe for interpersonal risk taking — Edmondson, 1999) and (b) the rate of episodic change experienced by the team. Four distinct patterns of use are identified: candid, ambivalent, conservative, and reluctant. Each of these usage patterns has implications for the learning opportunities teams may face and the perceived usefulness of a knowledge management system.
A Strategy for Interaction Site Prediction between Phospho-binding Modules and their Partners Identified from Proteomic Data*

Small and large scale proteomic technologies are providing a wealth of potential interactions between proteins bearing phospho-recognition modules and their substrates. Resulting interaction maps reveal such a dense network of interactions that the functional dissection and understanding of these networks often require to break specific interactions while keeping the rest intact. Here, we developed a computational strategy, called STRIP, to predict the precise interaction site involved in an interaction with a phospho-recognition module. The method was validated by a two-hybrid screen carried out using the ForkHead Associated (FHA)1 domain of Rad53, a key protein of Saccharomyces cerevisiae DNA checkpoint, as a bait. In this screen we detected 11 partners, including Cdc7 and Cdc45, essential components of the DNA replication machinery. FHA domains are phospho-threonine binding modules and the threonines involved in both interactions could be predicted using the STRIP strategy. The threonines T484 and T189 in Cdc7 and Cdc45, respectively, were mutated and loss of binding could be monitored experimentally with the full-length proteins. The method was further tested for the analysis of 63 known Rad53 binding partners and provided several key insights regarding the threonines likely involved in these interactions. The STRIP method relies on a combination of conservation, phosphorylation likelihood, and binding specificity criteria and can be accessed via a web interface at http://biodev.extra. cea.fr/strip/.
The effect of short exposure to coloured light on thermal perception: a study using Virtual Reality

This study investigates the effect of short exposure to coloured light on thermal perception. To give the impression of natural daylight passing through coloured filters, but avoiding the drawbacks of conducting an experiment with daylight, continuously changing due to daily and seasonal variations, and to weather conditions, we investigate the use of Virtual Reality as a means to control the visual conditions, creating a hybrid environment with thermal and visual stimuli from the real and virtual world, respectively. Two temperature levels (24 °C and 29 °C) are controlled in a climate chamber, while three visual conditions (orange, blue and neutral colour filters) are displayed in the Virtual Reality headset. Results of a between-subjects experiment show that the coloured light led to different thermal evaluations. In particular, under orange light conditions at 24 °C, subjects felt warmer, less comfortable and judged the thermal environment as less acceptable than under the other colours at the same temperature. The effect of short exposure to coloured light on thermal perception: a study using Virtual Reality. Available from: https://www.researchgate. net/publication/319963214_The_effect_of_short_exposure_to_coloured_light_on_thermal_perception_a_study_using_Virtual_Reality [accessed Sep 22, 2017].
A new workflow for x-ray fluorescence tomography: MAPStoTomoPy

X-ray fluorescence tomography involves the acquisition of a series of 2D x-ray fluorescence datasets between which a specimen is rotated. At the Advanced Photon Source at Argonne National Laboratory, the workflow at beamlines 2-ID-E and 21-ID-D (the Bionanoprobe, a cryogenic microscope system) has included the use of the program MAPS for obtaining elemental concentrations from 2D images, and the program TomoPy which was developed to include several tomographic reconstruction methods for x-ray transmission data. In the past, fluorescence projection images from an individual chemical element were hand-assembled into a 3D dataset for reconstruction using interactive tools such as ImageJ. We describe here the program MAPSToTomoPy, which provides a graphical user interface (GUI) to control a workflow between MAPS and TomoPy, with tools for visualizing the sinograms of projection image sequences from particular elements and to use these to help correct misalignments of the rotation axis. The program also provides an integrated output of the 3D distribution of the detected elements for subsequent 3D visualization packages.
An empirical study among science education majors in postgraduate students of an Australian university

This study aims to investigate the science education majors' experiences of employment, vocational self‐awareness, and self‐expectation, as well as the relationships among these variables in the university context based on the developmental‐contextual model of career development. Data were collected from a questionnaire survey of 815 science education majors in the selected universities. Through the use of regression analysis and statistical computation, we investigate the relationship between students' experience of finding employment upon graduation and a series of related variables and identify those factors that serve as boosters to self‐expectation. The results of this study found that the science education majors' experiences of employment directly and indirectly influenced their self‐expectation vis‐à‐vis the effect on their vocational self‐awareness. Findings point out to the increasingly important role university can play in developing and enhancing sufficient and appropriate employment and vocational information for science education majors. The science education departments of universities in Postgraduate students of Swinburne university may offer more sufficient vocational information about the occupations which the science education majors will enter after graduating to promote their vocational self‐awareness, such as occupational characteristics, occupational fringe benefits, occupational qualifications, and occupational ethics.
Pre-anaesthetic oral lansoprazole for the prophylaxis of Mendelson′s syndrome and impact of duodenogastric reflux on pH and volume of gastric contents

Background. Lansoprazole, a proton pump inhibitor, is used in peptic ulcers and other acid dy speptic disorders. The aim of this study is to determine whether a single oral dose of lansoprazole 30 mg, administered a night before surgery , is effective on pH and volume of gastric contents after excluding those samples contaminated with duodenogastric refluxate (DGR). Patients and Methods. This clinical trial was conducted in 112 adult patients of both sex, ASA phy sical status I-II, and aged 15-70 y r. The patients in group C (control) received placebo while group L (lansoprazole 30 mg) orally at 9.00 p.m. , a night before elective surgery . On the next day , gastric contents were aspirated with a large bore, multi-orifices gastric tube passed through an endotracheal tube placed blindly in esophagus after tracheal intubation and analy zed for the presence of bile salts, pH and volume. Results. Thirty three samples (30 %) out of 110 were contaminated with duodenal contents. DGR significantly affected the pH and volume in both the groups. Lansoprazole, after excluding those samples contaminated either with duodenal fluid or blood, significantly increased pH (P<0.0001), decreased volume (P=0.0326) and the proportion of the patients (10.52 % versus 30.76%) considered” at risk” compared with Placebo (P=0.0475) according to the criteria defined (pH ≤ 2.5 and volume ≥ 25 ml). Conclusions. Lansoprazole 30 mg given orally at 9.00 p.m. , a night before surgery , significantly decreased the number of patients at risk of aspiration pneumonitis at the time of induction of anesthesia if the aspiration of gastric contents occurs.
A High-Performance Optical Time-Domain Brillouin Distributed Fiber Sensor

A novel configuration for a Brillouin distributed fiber sensor based on Brillouin optical time-domain analysis is proposed. This configuration eliminates many intensity noise issues found in previous schemes. Resolution of 7 m all over a 47 km single-mode fiber was achieved and resolution down to 30 cm in a few kilometer fiber. Noise reduction makes possible measurements with a 16 times averaging.
Analyzing the Social Networks in Stanford ’ s CS 106 A

Our project is focused on understanding the social networks that exist in Stanford Computer Science courses; in particular, we aim to understand how these social networks affect student outcomes in these courses. For this paper, we are analyzing Stanford’s introductory Computer Science course, CS106A, using data from the course’s iteration in the Winter of 2017 when it was taught by Lecturer Chris Piech. We would like to explore what types of connections students form, and more broadly what types of communities exist, in CS106A. The idea of homophily, that “contact between similar people occurs at a higher rate than among dissimilar people” [1], is a driving concept motivating our investigation of CS106A. The Washington Post does an effective job explaining this phenomenon in their article “Three quarters of whites dont have any non-white friends” [2]. Figure 1 illustrates some of the findings of the article.
HighSpeed TCP for Large Congestion Windows

The proposals in this document are experimental. While they may be deployed in the current Internet, they do not represent a consensus that this is the best method for high-speed congestion control. In particular, we note that alternative experimental proposals are likely to be forthcoming, and it is not well understood how the proposals in this document will interact with such alternative proposals.
Hepatitis B virus X protein induced expression of the Nur77 gene.

Hepatitis B virus (HBV) X protein (HBx) plays an essential role in development of HBV-associated hepatocellular carcinoma (HCC). Recently, we reported that HBx induces Fas Ligand (FasL) expression, which may help HCC cells to evade host-immune surveillance. The aim of this study was to investigate the role of HBx in expression of Nur77, an orphan nuclear receptor implicated in the upregulation of FasL. When Chang X-34 expressing HBx under the control of a doxycycline-inducible promoter was examined, induction of Nur77 was observed following HBx expression. Blocking of Nur77 function by introduction of an antisense or a dominant negative mutant Nur77 significantly inhibited the induction of FasL, indicating that Nur77 plays critical roles in FasL expression. Further, a high-level expression of transcripts and DNA binding of Nur77 were observed in the HBV-integrated cell lines established from HCC patients that express HBx. These results suggested that Nur77 may contribute to leading the HBx-induced Fas/FasL signaling pathway which eliminates invading Fas-expressing lymphocytes.
Fostering Critical Thinking Skills in Students with Learning Disabilities: An Instructional Program

An instructional unit was developed to enhance the critical thinking skills of middle school and high school students with learning disabilities by teaching them the principles of scientific reasoning. Student-teacher dialogues were used to engage the students in an active process of critical inquiry. Students analyzed everyday information presented in brief magazine articles and advertisements by applying the principles of the scientific method. The students made statistically significant improvements in their ability to (a) identify the principal claim made in an article or advertisement, (b) graph the relevant data, and (c) evaluate the claims made in the article and explain their support or rejection of the claims based on data. After the instructional unit, the overall performance of the special education students exceeded that of a control group composed of regular education students who had not received instruction in critical thinking.
Antipsychotic prescribing and rehospitalisation in schizophrenia: A New Zealand study

ii ACKNOWLEDGMENTS . iv LIST OF TABLES . viii LIST OF FIGURES . x LIST OF ABBREVIATIONS . xi CO-AUTHORSHIP FORMS . xii SECTION 1: INTRODUCTION AND BACKGROUND . 1 1.
Compliance, adherence, and concordance: implications for asthma treatment.

Good-quality outcomes in asthma hinge not just on the availability of medications but also on their appropriate use by patients: optimal "self-management. " In asthma, low rates of adherence to prophylactic (preventer) medication are associated with higher rates of hospitalization and death. Many patients choose not to take their medication because they perceive it to be unnecessary or because they are concerned about potential adverse effects. Approximately one third of asthma patients have strong concerns about adverse effects from inhaled corticosteroids (ICS). These concerns are not just related to the experience of local symptoms attributed to ICS side effects, but also include more abstract concerns about the future, arising from the belief that regular use of ICS will result in adverse long-term effects or dependence. We need more effective ways of eliciting and addressing patients' concerns about ICS. The development of ICS options with an improved safety profile remains a key objective. However, the ideal solution is not just pharmacologic. We also need more effective ways of communicating the relative benefits and risks to patients in order to facilitate informed adherence. Clinicians must be prepared to work in an ongoing partnership with patients to ensure that they are offered a clear rationale as to why ICS are necessary and to address their concerns about potential adverse effects. This approach, based on a detailed examination of patients' perspectives on asthma and its treatment, and an open, nonjudgmental manner on the part of the clinician, is consistent with the idea of concordance.
Throughput analysis of CSMA protocol with Exponential Backoff

This paper studies the performance of Non-persistent CSMA protocols using K-Exponential Backoff collision resolution algorithms. We model it as a multi-queue single-server system with infinite buffer size and consider the service time distribution of Head-of-line packets as a Markov Chain to get the network throughput as well as the stability. The stable region of retransmission factor q is illustrated in examples of Exponential Backoff (K=∞). For throughput stability, we show the stabilized throughput can be obtained in networks even for infinite nodes.
Méthodes traditionnelles de gestion de l'eau et des sols en Afrique Occidentale soudano-sahélienne : définitions, fonctionnements, limites et améliorations possibles

Chacune de ces techniques présentent des limites et des fonctionnements quelque peu différents. Comme aujourd’hui de nombreux ONG se préoccupent de généraliser ces méthodes et de les améliorer, il nous paraît important de bien préciser leur typologie, leur fonctionnement, leurs limites et les améliorations possibles en vue d’accélérer la prise en charge par les paysans de la gestion de leur environnement. On peut les classer en deux catégories :
Parallel Coordinate Descent Newton for Large-scale L1-Regularized Minimization

The recent years have witnessed advances in parallel algorithms for large scale optimization problems. Notwithstanding demonstrated success, existing algorithms that parallelize over features are usually limited by divergence issues under high parallelism or require data preprocessing to alleviate these problems. In this work, we propose a Parallel Coordinate Descent Newton algorithm using multidimensional approximate Newton steps (PCDN), where the off-diagonal elements of the Hessian are set to zero to enable parallelization. It randomly partitions the feature set into $b$ bundles/subsets with size of $P$, and sequentially processes each bundle by first computing the descent directions for each feature in parallel and then conducting $P$-dimensional line search to obtain the step size. We show that: (1) PCDN is guaranteed to converge globally despite increasing parallelism; (2) PCDN converges to the specified accuracy $\epsilon$ within the limited iteration number of $T_\epsilon$, and $T_\epsilon$ decreases with increasing parallelism (bundle size $P$). Using the implementation technique of maintaining intermediate quantities, we minimize the data transfer and synchronization cost of the $P$-dimensional line search. For concreteness, the proposed PCDN algorithm is applied to $\ell_1$-regularized logistic regression and $\ell_2$-loss SVM. Experimental evaluations on six benchmark datasets show that the proposed PCDN algorithm exploits parallelism well and outperforms the state-of-the-art methods in speed without losing accuracy.
The Revised Illness Perception Questionnaire (IPQ-R)

This paper presents a revised version of the Illness Perception Questionnaire (IPQ-R), a recently developed and widely used quantitative measure of the five components of illness representations in Leventhal's self-regulatory model. The revised version stemmed from a need to deal with minor psychometric problems with two subscales, and to include additional subscales, assessing cyclical timeline perceptions, illness coherence, and emotional representations. Item selection was determined by principal components analyses which verified the factorial structure of the questionnaire in a sample of 711 patients from 8 different illness groups. Further analysis provided good evidence for both the internal reliability of the subscales and the short (3 week) and longer term (6 month) retest reliability. The IPQ-R also demonstrated sound discriminant, known group and predictive validity. While it is possible that the new subscales will vary in their applicability in different patient groups, the IPQ-R provides a more comprehensive and psychometrically acceptable assessment of the key components of patients' perceptions of illness.