Miracle-dz/UniFAR-FTUs huggingface dataset:
Improving iUnit Retrieval with Query Classification and Multi-Aspect iUnit Scoring: The IISR System at NTCIR-11 MobileClick Task

This paper describes our approach to the NTCIR-11 MobileClick task. Based on the assumption that dierent user intentions should be handled by dierent extraction/retrieval strategies, we rst classify each query into one of our eight dened query types and set the weights of the extraction methods accordingly. Next, we extract the relevant parts of the search results and rank the extracted sentences. Finally, we apply a rule-based approach to iUnit extraction. Our system achieves an nDCG@10 score of 0.2134 and a Q@10 score of 0.1573, outperforming the baseline by 23.9% and 42.4%, respectively. This dierence demonstrates the eectiveness of our query classication and multi-aspect iUnit scoring.
Drug Misuse: Taking a Narrative Approach as a Means of Exploring ‘Self-Change’

In this paper I explore the personal narrative of Jennifer; a woman who for the past ten years had been using ‘hard’ drugs. When interviewed Jennifer had been ‘sentenced’ to take part in an enforced treatment programme which aimed to facilitate ‘self-change’. The concept of ‘self-change’ would appear to convey a particular understanding of transitions, and changes in behaviour, rooted in assumptions around motivation, cognition and internal forces. In the research reported here the way in which someone ‘storied’ into a narrative of ‘self-change’ metaphorically represents her progress will be explored.
Norovirus and Histo-Blood Group Antigens: Demonstration of a Wide Spectrum of Strain Specificities and Classification of Two Major Binding Groups among Multiple Binding Patterns

ABSTRACT Noroviruses, an important cause of acute gastroenteritis, have been found to recognize human histo-blood group antigens (HBGAs) as receptors. Four strain-specific binding patterns to HBGAs have been described in our previous report. In this study, we have extended the binding patterns to seven based on 14 noroviruses examined. The oligosaccharide-based assays revealed additional epitopes that were not detected by the saliva-based assays. The seven patterns have been classified into two groups according to their interactions with three major epitopes (A/B, H, and Lewis) of human HBGAs: the A/B-binding group and the Lewis-binding group. Strains in the A/B binding group recognize the A and/or B and H antigens, but not the Lewis antigens, while strains in the Lewis-binding group react only to the Lewis and/or H antigens. This classification also resulted in a model of the norovirus/HBGA interaction. Phylogenetic analyses showed that strains with identical or closely related binding patterns tend to be clustered, but strains in both binding group can be found in both genogroups I and II. Our results suggest that noroviruses have a wide spectrum of host range and that human HBGAs play an important role in norovirus evolution. The high polymorphism of the human HBGA system, the involvement of multiple epitopes, and the typical protein/carbohydrate interaction between norovirus VLPs and HBGAs provide an explanation for the virus-ligand binding diversities.
International Classification of Functioning , Disability and Health ( ICF ) Core Sets for persons with sleep disorders : Results of the consensus process integrating evidence from preparatory studies

a ICF Research Branch of the Collaborating Centre for the WHO Family of International Classifications in German at SPF, Nottwil, Switzerland b Swiss Paraplegic Research (SPF), Nottwil, Switzerland c Institute for Health and Rehabilitation Sciences, Research Unit for Biopsychosocial Health, Ludwig-Maximilians-University, Munich, Germany d Berne Rehab Centre Heiligenschwendi, Heiligenschwendi, Switzerland e Department of Pneumology, University Hospital Insel, Berne, Switzerland f Department of Ambulatory and Respiratory Medicine, Swiss Paraplegic Centre, Nottwil, Switzerland g Wits Dial.A. Bed Sleep Laboratory, Faculty of Health Sciences, University of the Witwatersrand, Johanesburg, South Africa h Sleep Disorders Unit, Loewenstein Hospital Rehabilitation Center, Raanana, Israel i University of Pennsylvania School of Nursing/University of Pennsylvania School of Medicine’s Center for Sleep and Respiratory Neurobiology, Philadelphia, Pennsylvania, USA j Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia, USA k Department of Health Sciences and Health Policy at SPF, University of Lucerne, Switzerland l Sleep Clinic and Research Laboratory, Vitalmed Research Center, Finland m Department of Neurology, University of Helsinki, Finland
Early efficacy of and toxicity from lutetium-177-DOTATATE treatment in patients with progressive metastatic NET

Objective Lutetium-177 DOTA-D-Phe1-Tyr3-octreotide (177Lu-DOTATATE) is a treatment option for patients with well-differentiated metastatic neuroendocrine tumours. Our centre started administering this therapy in 2012. The aim of this study was therefore to analyse the first cohort of patients treated with 177Lu-DOTATATE to determine its early efficacy and toxicity. Patients and methods We retrospectively analysed patient, tumour and treatment characteristics, end-of-treatment outcome, time to progression and toxicity in 79 consecutive patients treated with 177Lu-DOTATATE who had progressive NET according to Response Evaluation Criteria in Solid Tumours criteria. Follow-up time was 12–40 months. Study of Kaplan–Meier plots, analysis of time to progression and multiple regression analysis of factors predictive of time to progression were performed. Results At end-of-treatment radiological restaging, 13% of patients were found to have partial response and 64% to have stable disease; 23% of patients progressed through treatment. Overall, 47% of patients demonstrated a reduction in chromogranin A levels. The overall estimated median time to progression from the start of treatment was 28 months for the entire cohort and 31, 30 and 5 months for those with partial response, stable disease and progressive disease, respectively. On multivariate regression analysis, higher grade of tumour was found to be significantly associated with shorter progression-free survival. Three patients experienced grade 1 haematotoxicity, five grade 1 nephrotoxicity and one grade 2 nephrotoxicity. Conclusion Early outcomes of patients treated with 177Lu-DOTATATE are similar to those in previously published series in terms of end-of-treatment efficacy and toxicity. This provides further evidence that this is a safe and efficacious form of treatment for patients with progressive metastatic neuroendocrine tumours.
The kinetics of chemotactic peptide-induced change in F-actin content, F-actin distribution, and the shape of neutrophils

Formyl-met-leu-phe (fMLP) induces actin assembly in neutrophils; the resultant increase in F-actin content correlates with an increase in the rate of cellular locomotion at fMLP concentrations less than or equal to 10(-8) M (Howard, T.H., and W.H. Meyer, 1984, J. Cell Biol., 98:1265-1271). We studied the time course of change in F-actin content, F-actin distribution, and cell shape after fMLP stimulation. F-actin content was quantified by fluorescence activated cell sorter analysis of nitrobenzoxadiazole-phallacidin-stained cells (Howard, T.H., 1982, J. Cell Biol., 95(2, Pt. 2:327a). F-actin distribution and cell shape were determined by analysis of fluorescence photomicrographs of nitrobenzoxadiazole-phallacidin-stained cells. After fMLP stimulation at 25 degrees C, there is a rapid actin polymerization that is maximal (up to 2.0 times the control level) at 45 s; subsequently, the F-actin depolymerizes to an intermediate F-actin content 5-10 min after stimulation. The depolymerization of F-actin reflects a true decrease in F-actin content since the quantity of probe extractable from cells also decreases between 45 s and 10 min. The rate of actin polymerization (3.8 +/- 0.3-4.4 +/- 0.6% increase in F-actin/s) is the same for 10(-10) - 10(-6) M fMLP and the polymerization is inhibited by cytochalasin D. The initial rate of F-actin depolymerization (6.0 +/- 1.0-30 +/- 5% decrease in F-actin/min) is inversely proportional to fMLP dose. The F-actin content of stimulated cells at 45 s and 10 min is greater than control levels and varies directly with fMLP dose. F- actin distribution and cell shape also vary as a function of time after stimulation. 45 s after stimulation the cells are rounded and F-actin is diffusely distributed; 10 min after stimulation the cell is polarized and F-actin is focally distributed. These results indicate that actin polymerization and depolymerization follow fMLP stimulation in sequence, the rate of depolymerization and the maximum and steady state F-actin content but not the rate of polymerization are fMLP dose dependent, and concurrent with F-actin depolymerization, F-actin is redistributed and the cell changes shape.
Reproducibility of metabolic measurements in malignant tumors using FDG PET.

UNLABELLED PET using 18F-fluorodeoxyglucose (FDG) is increasingly applied to monitor the response of malignant tumors to radiotherapy and chemotherapy. The aim of this study was to assess the reproducibility of serial FDG PET measurements to define objective criteria for the evaluation of treatment-induced changes. METHODS Sixteen patients participating in phase I studies of novel antineoplastic compounds were examined twice by FDG PET within 10 d while they were receiving no therapy. Standardized uptake values (SUVs), FDG net influx constants (Ki), glucose normalized SUVs (SUV(gluc)) and influx constants (K(i,gluc)) were determined for 50 separate lesions. The precision of repeated measurements was determined on a lesion-by-lesion and a patient-by-patient basis. RESULTS None of the parameters showed a significant increase or decrease at the two examinations. The differences of repeated measurements were approximately normally distributed for all parameters with an SD of the mean percentage difference of about 10%. The 95% normal ranges for spontaneous fluctuations of SUV, SUV(gluc), Ki and K(i,gluc) were determined to be +/-0.91, +/-1.14, +/-0.52 mL/100 g/min and +/-0.64 mL/100 g/min, respectively. Analysis on a lesion-by-lesion basis yielded similar results. CONCLUSION FDG PET provides several highly reproducible quantitative parameters of tumor glucose metabolism. Changes of a parameter that are outside the 95% normal range determined in this study may be used to define a metabolic response to therapy.
Genome-wide analysis and functional prediction of long non-coding RNAs in mouse uterus during the implantation window

Establishment of the receptive uterus is a crucial step for embryo implantation. In this study, the expression profiles and characterization of long non-coding RNAs (lncRNAs) in pregnant mouse uteri on day 4, day 5 at implantation sites and inter-implantation sites were conducted using RNA-seq. A total of 7,764 putative lncRNA transcripts were identified, including 6,179 known lncRNA transcripts and 1,585 novel lncRNA transcripts. Bioinformatics analysis of the cis and trans lncRNA targets showed that the differentially expressed lncRNAs were mainly involved in tissue remodelling, immune response and metabolism-related processes, indicating that lncRNAs could be involved in the regulation of embryo implantation. We also discovered that differentially expressed lncRNAs might regulate multiple signalling pathways that play an important role in the regulation of embryo implantation. In addition, nine known lncRNAs and four novel lncRNAs were randomly selected and validated by qRT-PCR. The expression of Tug1, Neat1, Gas5, Malat1, H19 and Rmst were significantly regulated in the mouse uterus during the implantation window. Our results are the first to systematically identify lncRNAs in the mouse uterus and provide a catalogue of lncRNAs for further understanding their functions in pregnant mouse uteri during the implantation window.
Bis[6-methoxy-2-[(4-methylphenyl)iminiomethyl]phenolate-κO 1]tris(nitrato-κ2 O,O′)ytterbium(III) monohydrate

The crystal structure of title compound, [Yb(NO(3))(3)(C(15)H(15)NO(2))(2)]·H(2)O, contains two Schiff base 2-[(4-methyl-phen-yl)imino-meth-yl]-6-methoxy-phenol (HL) ligands, three independent nitrate ions that chelate to the ytterbium(III) ion in an O,O'-bidentate manner and an uncoordinated water mol-ecule. The coordination number of the Yb(III) ion is eight. The HL ligands chelate with a strong Yb-O(phenolate) bond and a weak Yb-O(meth-oxy) contact. The latter augments the coordination polyhedron to give a YbO(10) bicapped square antiprism. Classical inter-molecular O-H⋯O and N-H⋯O hydrogen bonds as well as weak C-H⋯O contacts contribute to the stability of the structure.
Running head : Long-Term Symbolic Learning Long-Term Symbolic Learning

What are the characteristics of long-term learning? We investigated the characteristics of long-term, symbolic learning using the Soar and ACT-R cognitive architectures running cognitive models of two simple tasks. Long sequences of problems were run collecting data to answer fundamental questions about long-term, symbolic learning. We examined whether symbolic learning continues indefinitely, how the learned knowledge is used, and whether performance degrades over the long term. We report that in both systems, symbolic learning eventually stopped, learned knowledge was used differently in different stages but the resulting production knowledge was used uniformly, and, finally, both Soar and ACT-R do eventually suffer from degraded performance with long-term continuous learning. We also discuss ACT-R implementation and theoretic causes of ACT-R’s performance problems and settings that appear to avoid the performance problems in ACT-R. Kennedy, W.G. , & Trafton, J.G. (in press 2007) Long-term Symbolic Learning. Cognitive Systems Research. Available from http://www.mllab. com
Cryoplasty offers no advantage over standard balloon angioplasty for the treatment of in-stent stenosis

In-stent restenosis is the primary failure mode of endovascular treatment of occlusive disease in the femeropopliteal segment. Cryoplasty has been proposed to reduce intimal hyperplasia through induction of apoptosis. We sought to evaluate the efficacy of cryoplasty for treatment of in-stent restenosis compared to conventional balloon angioplasty (CBA). After IRB approval, a retrospective record review was performed of reinterventions for in-stent restenosis by a single vascular surgery group at a university hospital. Reinterventions involving cryoplasty and CBA were evaluated at 1, 3, 6 and 12 months after intervention with duplex imaging to identify significant recurrent stenosis utilizing established velocity criteria. Data collected included basic demographic information and comorbidities as well as time to restenosis. Statistical analysis was performed using Kaplan–Meier survival curves with the log rank test, Wilcoxon rank test, and Cox proportional hazards models. From December 2004 to November 2007, 76 reinterventions were performed using CBA (n = 39) or cryoplasty (n = 37) for in-stent restenosis without placement of additional stents. Periprocedural technical success (>30% residual stenosis) was 100% for both groups, with no complications. The two cohorts were statistically similar in mean age, gender, comorbidities, tobacco use and use of statins, aspirin and Plavix. However, the mean lesion length was significantly longer in the cryoplasty cohort (CBA: 140.9 mm, Cyro: 191.7 mm; P = 0.032). The mean time to recurrent stenosis or need for additional secondary intervention was significantly shorter for the cyroplasty cohort than for the CBA, 4.09 and 10.79 months, respectively (P = .0001). Recurrent stenosis-free survival was significantly lower in the cyroplasty cohort at 3 months (CBA: 96.9%, Cyro: 88.9%) and 6 months (CBA: 84.0%, Cyro: 43.8%; P = .0089). Cyroplasty as a modality for treatment of in-stent stenosis in the femoropopliteal segment offers no benefit over CBA.
Automatic PCB Inspection Algorithms: A Survey

The importance of the inspection process has been magnified by the requirements of the modern manufacturing environment. In electronics mass-production manufacturing facilities, an attempt is often made to achieve 100% quality assurance of all parts, subassemblies, and finished goods. A variety of approaches for automated visual inspection of printed circuits have been reported over the past two decades. In this survey, algorithms and techniques for the automated inspection of printed circuit boards are examined. A classification tree for these algorithms is presented and the algorithms are grouped according to this classification. This survey concentrates mainly on image analysis and fault detection strategies; these also include state-of-the-art techniques. A summary of the commercial PCB inspection systems is also presented.
Materialization Calculus for Contexts in the Semantic Web

Representation of context dependent knowledge in the Semantic Web is becoming a recognized issue and a number of DL-based formalisms have been proposed in this regard: among them, in our previous works we introduced the Contextualized Knowledge Repository (CKR) framework. In CKR, contexts are organized hierarchically according to a broader-narrower relation and knowledge propagation across contexts is limited among contexts hierarchically related. In several applications, however, this structure is too restrictive, as they demand for a more flexible and scalable framework for representing and reasoning about contextual knowledge. In this work we present an evolution of the original CKR (based on OWL RL), where contexts can be organized in any graph based structure (declared as a metaknowledge base) and knowledge propagation is allowed among any pair of contexts via a new ”evaluate-in-context” operator. In particular, we detail a materialization calculus for reasoning over the revised CKR framework and prove its soundness and completeness. Moreover, we outline the current implementation of the calculus on top of SPRINGLES, an extension of standard RDF triple stores for representing and rule-based inferencing over multiple RDF named graphs.
Detection and differentiation of Cryptosporidium spp . in human clinical samples 1 using real-time PCR . 2 3

Detection and differentiation of Cryptosporidium spp. in human clinical samples 1 using real-time PCR. 2 3 Stephen J. Hadfield, Guy Robinson, Kristin Elwin, Rachel M. Chalmers* 4 5 UK Cryptosporidium Reference Unit, Public Health Wales Microbiology, Swansea, 6 UK 7 8 *Corresponding author: 9 UK Cryptosporidium Reference Unit 10 Public Health Wales Microbiology 11 Singleton Hospital 12 Sketty Lane 13 Swansea 14 SA2 8QA 15 United Kingdom 16 Tel: + 44 1792 285341 17 Fax: + 44 1792 202320 18 E-mail address: Rachel.Chalmers@wales.nhs. uk 19 20 21 Running title: Detection of Cryptosporidium spp. by real-time PCR 22 23 24 Copyright © 2010, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. J. Clin. Microbiol. doi:10.1128/JCM.01733-10 JCM Accepts, published online ahead of print on 22 December 2010
Existence and uniqueness of fair rate allocations in lossy wireless networks

To extend established concepts of fair resource allocation in wired networks to wireless networks, wired model assumptions must be adapted to be relevant for wireless networks as for example, in wireless networks losses due to environmental conditions may occur even in the absence of queueing congestion. Thus fundamental questions of the existence and uniqueness of fair rate allocations must be reconsidered. We treat wireless networks characterized by lossy channels, spatial channel reuse, multiple routes and multiple frequencies. We establish the existence and uniqueness of utility fair and max-min fair solutions and that, as loss rates decrease, fair allocations converge to the loss-less ones.
A New Image Analysis Framework for Latin and Italian Language Discrimination

The paper presents a new framework for discrimination of Latin and Italian languages. The first phase maps the text in the given language into a uniformly coded text. It is based on the position of each letter of the script in the text line and its height, derived from its energy profile. The second phase extracts run-length texture measures from the coded text given as 1-D image, by producing a feature vector of 11 values. The obtained feature vectors are adopted for language discrimination by using a clustering algorithm. As a result, the distinction between the two languages is perfectly realized with an accuracy of 100% on a complex database of documents in Latin and Italian languages.
A New Method for Solving Hard Satis ability Problems

We introduce a greedy local search procedure called GSAT for solving propositional satis ability problems Our experiments show that this procedure can be used to solve hard randomly generated problems that are an order of magnitude larger than those that can be handled by more traditional approaches such as the Davis Putnam procedure or resolution We also show that GSAT can solve structured satis ability problems quickly In particular we solve encodings of graph coloring problems N queens and Boolean induction General application strategies and limitations of the ap proach are also discussed GSAT is best viewed as a model nding procedure Its good performance suggests that it may be advan tageous to reformulate reasoning tasks that have tra ditionally been viewed as theorem proving problems as model nding tasks
Impressions that Arouse an Auditor's Suspicion of Lying in an Interview

This study models the process by which auditors draw a suspicion of lying from an interviewee's behavior and tests the model with perceptions and beliefs collected from 147 auditors after they observed an interview. An understanding of the way auditors become suspicious of lying may lead to improvements in their deception‐detection training. The proposed structural model includes impressions of the interviewee as intervening variables between perceptions of behavior and suspicion of lying. It was evaluated using SEM. The results show the instrumentality of two impressions, uneasiness and non‐informativeness. An additional finding is that mental stress, which can be more intense for liars than for truth tellers, is not a suspicious behavior. Auditors may disregard signs of mental stress because interviewees typically have to answer thought‐provoking questions, thereby confounding the mental stress of lying with the mental stress of the interview.
Hyperkernel Construction for Support Vector Machines

Construction of kernel functions is crucial for research and application of support vector machines (SVM). In this paper, we propose a combinatorial construction of hyperkernel functions for SVM. We first analyze the under and over-learning phenomena of common kernel functions. Then, we construct hyperkernel function with a polynomial combination of common kernels, and prove the Mercer condition of the hyperkernel. Finally, we experiment both on simulation and benchmark data to demonstrate the performance of hyperkernel for SVM. The theoretical proofs and experimental results illuminate the validity and feasibility of hyperkernel.
Scalable and Systolic Montgomery Multipliers over GF(2m)

This work presents a novel scalable and systolic Montgomery's algorithm in GF(2m). The proposed algorithm is based on the Toeplitz matrix-vector representation, which obtains the scalable and systolic Montgomery multiplier in a flexible manner, and can adapt to the required precision. Analytical results indicate that the proposed multiplier over the generic field of GF(2m) has a latency of d + n(2n + 1), where n = ⌈m/d⌉, and d denotes the selected digital size. The latency is reduced to d + n(n + 1) clock cycles when the field is constructed from generalized equally-spaced polynomials. Since the selected digital size is d ≥ 5 bits, the proposed architectures have lower time-space complexity than traditional digit-serial multipliers. Moreover, the proposed architectures have regularity, modularity and local interconnect ability, making them very suitable for VLSI implementation.