Miracle-dz/UniFAR-FTUs huggingface dataset:
Customer connection creates a winning product: building success with contextual techniques

51 i n t e r a c t i o n s. j a n u a r y + f e b r u a r y 1 9 9 9 a r t i c l e from the management level to the development teams. Einstein said, " Love is a better teacher than duty. " Likewise for developers' adoption of new techniques. In Hewlett Packard's (HP) Enterprise Systems Group (ESG), contextual techniques have been used by developers to understand product requirements for 5 years at the product and lab levels. In ESG's Unix Development Lab (UDL), HP has trained more than 50 engineers in contextual inquiry and data modeling and more than 20 engineers and managers have completed InContext's full Contextual Design Series [1]. This article describes the experience of HP's Ignition team and its successful delivery of a new product, Ignite-UX, using a combination of contextual, usability, and standard software development methods. The customer acclaim and success of the Ignite-UX product have contributed to ESG's decision to apply even more contextual design methods in a recent division-wide initiative [2]. Opportunity In 1996, the Ignition team faced the challenge of developing the next generation of tools for installation and deployment of the HP-UX operating system. This product would help System Administrators quickly and easily install and update HP workstation and server systems with custom configurations. With this effort, the team was to replace two existing , similar products with a single new product to reduce development and resource costs. These existing products served different customers with slightly different work goals and T High-speed connections such as cable modems will let content producers add video, sound and 3-D to Web sites to offer…what? Nobody knows, but it's sure to transform the medium. This curious quote appeared in USA Today during CHI'98 as we prepared for our SIG session on " Success with Contextual Techniques. " As product designers, we are in the business of changing how people work through the purposeful application of new technology, not just the transformation of technology itself. Creating products that fit how people work requires a shift from a technology-centered development practice to a customer-centered design culture. This article describes the successful application of contextual techniques in a real-world software development organization. The success of the resulting product success was clearly linked to the use of these techniques and has contributed …
Barreiras e determinantes para a prática de atividade física em adolescentes

The aim of this survey was to identify the physical activities barriers of high school students from private school system of Sao Paulo city. The sample was composited by 1,738 adolescents (16.6±1.0 years old), with social economic strata classified at A, B and C levels, that attended regular classes at morning in eight high schools in south region of Sao Paulo city. Data collecting was issued by a self-respond questionnaire addressed by "Agita Sao Paulo Pro - gram" which allows identifying barriers and determinants factors for physical activity practice. The barriers that presented higher prevalence were; the lack of interest in exercise (25.7%) and lack of knowledge how to exercise (25.2%), with higher prevalence in male group gender and among adolescents that reported do not know the purposes or other information about "Agita Sao Paulo Program". Data of third grade students, presented that barriers as lack of interest in exercise (54.1%) and lack of time (13.0%). Thus it is important to create a positive environ- ment to stimulate the physical activity practice reducing the barriers increase the of physical activity level at school time.
Disruption of STAT5b-Regulated Sexual Dimorphism of the Liver Transcriptome by Diverse Factors Is a Common Event

Signal transducer and activator of transcription 5b (STAT5b) is a growth hormone (GH)-activated transcription factor and a master regulator of sexually dimorphic gene expression in the liver. Disruption of the GH hypothalamo-pituitary-liver axis controlling STAT5b activation can lead to metabolic dysregulation, steatosis, and liver cancer. Computational approaches were developed to identify factors that disrupt STAT5b function in a mouse liver gene expression compendium. A biomarker comprised of 144 STAT5b-dependent genes was derived using comparisons between wild-type male and wild-type female mice and between STAT5b-null and wild-type mice. Correlations between the STAT5b biomarker gene set and a test set comprised of expression datasets (biosets) with known effects on STAT5b function were evaluated using a rank-based test (the Running Fisher algorithm). Using a similarity p-value ≤ 10−4, the test achieved a balanced accuracy of 99% and 97% for detection of STAT5b activation or STAT5b suppression, respectively. The STAT5b biomarker gene set was then used to identify factors that activate (masculinize) or suppress (feminize) STAT5b function in an annotated mouse liver and primary hepatocyte gene expression compendium of ~1,850 datasets. Disruption of GH-regulated STAT5b is a common phenomenon in liver in vivo, with 5% and 29% of the male datasets, and 11% and 13% of the female datasets, associated with masculinization or feminization, respectively. As expected, liver STAT5b activation/masculinization occurred at puberty and suppression/feminization occurred during aging and in mutant mice with defects in GH signaling. A total of 70 genes were identified that have effects on STAT5b activation in genetic models in which the gene was inactivated or overexpressed. Other factors that affected liver STAT5b function were shown to include fasting, caloric restriction and infections. Together, these findings identify diverse factors that perturb the hypothalamo-pituitary-liver GH axis and disrupt GH-dependent STAT5b activation in mouse liver.
An inference mechanism for question answering

This work describes an inference mechanism applied to AliQAn Question Answering System for Spanish in open domain. AliQAn is based fundamentally on the use of syntactic patterns to identify the possible answers. An inference mechanism is applied to the questions set of economic type. In this way, our system improves the accuracy of this question type from 33% to 57%.
Physiological, behavioral and biochemical adaptations of intertidal fishes to hypoxia

Summary Hypoxia survival in fish requires a well-coordinated response to either secure more O2 from the hypoxic environment or to limit the metabolic consequences of an O2 restriction at the mitochondria. Although there is a considerable amount of information available on the physiological, behavioral, biochemical and molecular responses of fish to hypoxia, very little research has attempted to determine the adaptive value of these responses. This article will review current attempts to use the phylogenetically corrected comparative method to define physiological and behavioral adaptations to hypoxia in intertidal fish and further identify putatively adaptive biochemical traits that should be investigated in the future. In a group of marine fishes known as sculpins, from the family Cottidae, variation in hypoxia tolerance, measured as a critical O2 tension (Pcrit), is primarily explained by variation in mass-specific gill surface area, red blood cell hemoglobin–O2 binding affinity, and to a lesser extent variation in routine O2 consumption rate (). The most hypoxia-tolerant sculpins consistently show aquatic surface respiration (ASR) and aerial emergence behavior during hypoxia exposure, but no phylogenetically independent relationship has been found between the thresholds for initiating these behaviors and Pcrit. At O2 levels below Pcrit, hypoxia survival requires a rapid reorganization of cellular metabolism to suppress ATP consumption to match the limited capacity for O2-independent ATP production. Thus, it is reasonable to speculate that the degree of metabolic rate suppression and the quantity of stored fermentable fuel is strongly selected for in hypoxia-tolerant fishes; however, these assertions have not been tested in a phylogenetic comparative model.
Towards Multidocument Summarization by Reformulation: Progress and Prospects

By synthesizing information common to retrieved documents, multi-document summarization can help users of information retrieval systems to find relevant documents with a minimal amount of reading. We are developing a multidocument summarization system to automatically generate a concise summary by identifying and synthesizing similarities across a set of related documents. Our approach is unique in its integration of machine learning and statistical techniques to identify similar paragraphs, intersection of similar phrases within paragraphs, and language generation to reformulate the wording of the summary. Our evaluation of system components shows that learning over multiple extracted linguistic features is more effective than information retrieval approaches at identifying similar text units for summarization and that it is possible to generate a fluent summary that conveys similarities among documents even when full semantic interpretations of the input text are not available.
Distinct neural correlates of the preference‐related valuation of supraliminally and subliminally presented faces

Recent neuroimaging studies have investigated the neural substrates involved in the valuation of supraliminally presented targets and the subsequent preference decisions. However, the neural mechanisms of the valuation of subliminally presented targets, which can guide subsequent preference decisions, remain to be explored. In the present study, we determined whether the neural systems associated with the valuation of supraliminally presented faces are involved in the valuation of subliminally presented faces. The subjects were supraliminally and subliminally presented with faces during functional magnetic resonance imaging (fMRI). Following fMRI, the subjects were presented with pairs of faces and were asked to choose which face they preferred. We analyzed brain activation by back‐sorting the fMRI data according to the subjects' choices. The present study yielded two main findings. First, the ventral striatum and the ventromedial prefrontal cortex predict preferences only for supraliminally presented faces. Second, the dorsomedial prefrontal cortex may predict preferences for subliminally presented faces. These findings indicate that neural correlates of the preference‐related valuation of faces are dissociable, contingent upon whether the subjects consciously perceive the faces. Hum Brain Mapp 36:2865–2877, 2015. © 2015 Wiley Periodicals, Inc.
Mitochondrial protein import: involvement of the mature part of a cleavable precursor protein in the binding to receptor sites.

The precursor of F0‐ATPase subunit 9 was bound to mitochondria in the absence of a mitochondrial membrane potential (delta psi). Binding was mediated by a protease‐sensitive component on the mitochondrial surface. When delta psi was reestablished, bound precursor was directly imported without prior release from the mitochondrial membranes. A chimaeric protein consisting of the complete subunit 9 precursor fused to cytosolic dihydrofolate reductase (DHFR) was also specifically bound to mitochondria in the absence of delta psi. Two other fusion proteins, consisting either of the entire presequence of subunit 9 and DHFR or of part of the presequence and DHFR, were imported in the presence of delta psi. In the absence of delta psi, however, specific binding to mitochondria did not take place. We suggest that the hydrophobic mature part of subunit 9 is involved in the delta psi‐independent binding of the subunit 9 precursor to receptor sites on the mitochondrial surface.
Linkage between Fitness of Yeast Cells and Adenylate Kinase Catalysis

Enzymes have evolved with highly specific values of their catalytic parameters kcat and KM. This poses fundamental biological questions about the selection pressures responsible for evolutionary tuning of these parameters. Here we are address these questions for the enzyme adenylate kinase (Adk) in eukaryotic yeast cells. A plasmid shuffling system was developed to allow quantification of relative fitness (calculated from growth rates) of yeast in response to perturbations of Adk activity introduced through mutations. Biophysical characterization verified that all variants studied were properly folded and that the mutations did not cause any substantial differences to thermal stability. We found that cytosolic Adk is essential for yeast viability in our strain background and that viability could not be restored with a catalytically dead, although properly folded Adk variant. There exist a massive overcapacity of Adk catalytic activity and only 12% of the wild type kcat is required for optimal growth at the stress condition 20°C. In summary, the approach developed here has provided new insights into the evolutionary tuning of kcat for Adk in a eukaryotic organism. The developed methodology may also become useful for uncovering new aspects of active site dynamics and also in enzyme design since a large library of enzyme variants can be screened rapidly by identifying viable colonies.
An Elegant Solution: An Alternative Ultra-Wideband Transceiver Based on Stepped-Frequency Continuous-Wave Operation and Compressive Sensing

For more than 50 years, since early work beginning in 1960, ultra-wideband (UWB) technology has been developed to analytically verify the transient behavior of a class of transverse electromagnetic mode microwave networks. The U.S. Federal Communications Commission has defined UWB as operating with a minimum fractional bandwidth of 20% or with a minimum -10-dB bandwidth of 500 MHz.
An ontology development approach for enhancing search-ability of record management systems

Technologies for record management systems have not been sufficient in meeting industry's demands, especially for providing appropriate search options that are context-sensitive. Ontology has been a tool for providing useful vocabulary and meaning that enable decision-makers to find the relevant information quickly. This paper discusses an ontology development approach that is used to improve search-ability of an existing electronic record management system (EDRMS). The discussion in the paper focuses on various options of an appropriate ontology specification for the structural composition of the EDRMS. The adapted approach helps define technical components that are interrelated within the system. The approach can be reused in other projects in that an ontology development would be a vital part of solution design process. Application-based evaluation strategy was used to evaluate the developed proof of concept prototype. Result has indicated positive outcome in relation to improved search-ability.
Words and the World

Can what we know change what we see? Does language affect cognition and perception? The last few years have seen increased attention to these seemingly disparate questions, but with little theoretical advance. We argue that substantial clarity can be gained by considering these questions through the lens of predictive processing, a framework in which mental representations—from the perceptual to the cognitive—reflect an interplay between downward-flowing predictions and upward-flowing sensory signals. This framework provides a parsimonious account of how (and when) what we know ought to change what we see and helps us understand how a putatively high-level trait such as language can impact putatively low-level processes such as perception. Within this framework, language begins to take on a surprisingly central role in cognition by providing a uniquely focused and flexible means of constructing predictions against which sensory signals can be evaluated. Predictive processing thus provides a plausible mechanism for many of the reported effects of language on perception, thought, and action, and new insights on how and when speakers of different languages construct the same “reality” in alternate ways.
Secure Business Process Engineering: a socio-technical approach

Dealing with security is a central activity for todays organizations. Security breaches impact on the activities executed in organizations, preventing them to execute their business processes and, therefore, causing millions of dollars of losses. Security by design principles underline the importance of considering security as early as during the design of organizations to avoid expensive fixes during later phases of their lifecycle. However, the design of secure business processes cannot take into account only security aspects on the sequences of activities. Security reports in the last years demonstrate that security breaches are more and more caused by attacks that take advantage of social vulnerabilities. Therefore, those aspects should be analyzed in order to design a business process robust to technical and social attacks. Still, the mere design of business processes does not guarantee that their correct execution, such business processes have to be correctly implemented and performed. We propose SEcure Business process Engineering (SEBE), a method that considers social and organizational aspects for designing and implementing secure business processes. SEBE provides an iterative and incremental process and a set of verification of transformation rules, supported by a software tool, that integrate different modeling languages used to specify social security aspects, business processes and the implementation code. In particular, SEBE provides a new modeling language which permits to specify business processes with security concepts and complex security constraints. We evaluated the effectiveness of SEBE for engineering secure business processes with two empirical evaluations and applications of the method to three real scenarios.
An Empirical Study of Consumers Adopting Mobile Commerce in Taiwan: Analyzed by Structural Equation Modeling

While online technologies and applications are rapidly and widely utilized and adopted in e-commerce, it is extremely important to better understand the perceptions of consumers’ use, and acceptance in mobile commerce (MC). This paper adopts the extended technology acceptance model (TAM2) and integrated it with the innovation diffusion theory and the perceived risk variable to model users’ acceptance of using MC. An Empirical study was conducted, the proposed research model was evaluated by structural equation modeling, and then confirmatory factor analysis was applied to test if the empirical data confirmed to the presumed model.
The Aesthetics of Imagination in Design

In The Aesthetics of Imagination in Design, Mads Folkmann investigates design in both material and immaterial terms. Design objects, Folkmann argues, will always be dual phenomena -- material and immaterial, sensual and conceptual, actual and possible. Drawing on formal theories of aesthetics and the phenomenology of imagination, he seeks to answer fundamental questions about what design is and how it works that are often ignored in academic research. Folkmann considers three conditions in design: the possible, the aesthetic, and the imagination. Imagination is a central formative power behind the creation and the life of design objects; aesthetics describes the sensual, conceptual, and contextual codes through which design objects communicate; the concept of the possible -- the enabling of new uses, conceptions, and perceptions -- lies behind imagination and aesthetics. The possible, Folkmann argues, is contained as a structure of meaning within the objects of design, which act as part of our interface with the world. Taking a largely phenomenological perspective that reflects both continental and American pragmatist approaches, Folkmann also makes use of discourses that range from practice-focused accounts of design methodology to cultural studies. Throughout, he offers concrete examples to illustrate theoretical points. Folkmann's philosophically informed account shows design -- in all its manifestations, from physical products to principles of organization -- to be an essential medium for the articulation and transformation of culture.
Microglandular Adenosis

Microglandular adenosis (MGA) of the breast is a very rare and benign proliferative lesion. Most patients complain of a palpable breast mass that may arouse a clinical suspicion of breast cancer. Histopathologically, it is hard to distinguish MGA from breast cancer because of the lack of a myoepithelial layer and infiltrative proliferation. Several studies have reported a strong relationship between MGA and carcinoma arising in MGA, so the mass should be excised completely in cases of MGA determined from a core needle biopsy rather than observation. A 72-years-old woman presented with a palpable breast mass. On physical examination, a mass was palpable in the right upper outer quadrant area and somewhat fixed to the surrounding tissues and pectoralis major muscle. We could not detect any mass or dense lesion on mammography because of a grade 4 dense breast. Ultrasonographic findings revealed a low echoic lesion with indistinct margins. The result of a core needle biopsy was MGA, which was confirmed by excision. We report one case of MGA, which was believed to breast cancer clinically.
The design and implementation of interactive game based on PTAM

PTAM (Parallel Tracking and Mapping) is the popular camera tracking technology. In this paper, we design and implement an interaction game of Egg Catcher based on PTAM. To deal with the problems occurred when camera is in fast-moving or scene lighting changes, we introduce a described method of feature point. The method will firstly do some pre-treatment of rotating to the images according to the main direction of the feature point, and adopt the adaptive threshold method to improve the test definition of the feature points. And the robustness of it can be greatly improved even under the circumstance when camera is in fast moving or scene lighting changes. At last, we implement a real-time interactive games based on the improved PTAM technology.
No major effect of twinning on autistic traits

Background: It has been questioned whether the process of twinning might be a risk factor for autism spectrum conditions (ASC) and autistic traits. Aim: We sought to determine whether autistic traits and probable disorder, as measured by the Childhood Autism Spectrum Test (CAST), were more pronounced in twins compared to singletons. Samples: Data were analyzed from two large population‐based samples of UK children, twins (n = 5,142 twin pairs, aged 8 years) and singletons (n = 2,805, aged 5–9 years). Results: Distributions of CAST scores in both groups were negatively skewed and scores for twins were more variable than singletons. Mean CAST total scores and standard errors (SE) were not significantly different for twins (5.1; SE 0.04) compared to singletons (4.9; SE 0.08). Moreover, contrary to expectations, the likelihood of scoring above the threshold for possible ASC was significantly lower in the twins than the singletons (OR = 0.69; P = 0.002). Subsidiary analyses of CAST scores according to sex, twin type, and subscale scores representing the subdomains of autism found a few significant differences (P<0.01), but the effect sizes for these differences were small and none exceeded η2 = 0.005. The explanation for these small differences remains obscure, but the very small effect sizes mean they are of little importance. Conclusions: Our results do not provide evidence to support twinning as a risk factor in the development of autistic traits. Autism Res 2011,4:377–382. © 2011 International Society for Autism Research, Wiley Periodicals, Inc.