Miracle-dz/UniFAR-FTUs huggingface dataset:
Gerontological Social Work Student-Delivered Respite: A Community-University Partnership Pilot Program

ABSTRACT This study describes a community-university partnership to support a gerontological social work student-delivered respite program, the Houseguest Program (Houseguest). Houseguest was designed using a community-engaged scholarship model of integrating research, teaching, and service. Houseguest was piloted with a small group of community-dwelling, coresiding dementia caregivers and care recipients. We examined caregivers’ experiences with student-delivered respite using qualitative data analysis. Thematic analysis produced 8 themes: (a) respite from full time caregiving role, (b) information on caregiving strategies, (c) no-cost supportive services, (d) opportunity for care recipients to socialize, (e) tailored activities for care recipients, (f) rapport-building between students and family dyad, (g) reciprocity between students and family dyad, and (h) program continuation. We conclude with a proposed community-engaged scholarship model for dementia caregiving. Through a community-university partnership, Houseguest reduced the impact of caregiver burden and created an opportunity for students to serve families affected by dementia through respite and tailored activities.
Ebola Virus Disease in Mice with Transplanted Human Hematopoietic Stem Cells

ABSTRACT The development of treatments for Ebola virus disease (EVD) has been hampered by the lack of small-animal models that mimick human disease. Here we show that mice with transplanted human hematopoetic stem cells reproduce features typical of EVD. Infection with Ebola virus was associated with viremia, cell damage, liver steatosis, signs of hemorrhage, and high lethality. Our study provides a small-animal model with human components for the development of EVD therapies.
Cloud-based system for waste electrical and electronic equipment

The growing market of electronic appliances is nowadays introducing a new kind of problem: the disposal management of a great quantity of broken or simply outdated electric and electronic devices. Sometimes the equipment contain dangerous or precious materials, that must be handled carefully. Furthermore, several good and valuable components on broken equipment could be reused. In this work, we present a Web based system conceived and designed to maintain all those information that can improve the end-of-life management of an electronic appliance. The cloud database can be easily accessed using the RFId technology, allowing the traceability of the equipment and the single components in the manufacturing, use, reuse and end-of-life phases.
Unaffected twins discordant for affective disorders show changes in anterior callosal white matter microstructure

The neurobiological mechanisms mediating an increased risk to develop affective disorders remain poorly understood. In a group of individuals with a family history of major depressive (MDD) or bipolar disorder (BD), we investigated the microstructural properties of white matter fiber tracts, that is, cingulum bundle, uncinate fasciculus, anterior limb of the internal capsule, and corpus callosum, that facilitate the communication between brain regions implicated in affective disorders.
Replication of Orgyia pseudotsugata baculovirus DNA: lef-2 and ie-1 are essential and ie-2, p34, and Op-iap are stimulatory genes.

A transient DNA replication assay was used to identify genes located within m.u. 90.5-7.0 of the Orgyia pseudotsugata multinucleocapsid nuclear polyhedrosis virus (OpMNPV) genome that influenced replication of a reporter plasmid containing an OpMNPV origin of replication, when cotransfected into uninfected Lymantria dispar cells. The viral transactivator ie-1 and a 2.4-kb subclone were found to be essential for replication. The 2.4-kb region was sequenced and open reading frames were identified. Replication assays using subclones from this region identified a gene called late expression factor 2 (lef-2), as the essential replication gene. The OpMNPV lef-2 gene encodes a protein with a predicted molecular weight of 22.7 kDa (204 amino acids) and exhibits 54.7% amino acid sequence identity with its homolog in the genome of the Autographa californica MNPV. Transcriptional mapping using both Northern blot and S1 nuclease protection assays demonstrated that OpMNPV lef-2 was expressed at both early and late times postinfection as a transcript of about 1.6 kb. The early transcript initiated approximately 30 nt downstream of a TAATA box, whereas the late transcript initiated from within a late promoter consensus motif. In addition, we identified three genes stimulatory for DNA replication including two OpMNPV transcriptional activators (ie-2 and p34) and Op-iap, which is the functional analog of the AcMNPV p35 gene that inhibits apoptosis in AcMNPV-infected Spodoptera frugiperda cells.
Hypothesis Preservation Approach to Scene Text Recognition with Weighted Finite-State Transducer

This paper shows that the use of Weighted Finite-State Transducer (WFST) significantly eliminates large-scale ambiguity in scene text recognition, especially for Japanese Kanji characters. The proposed method consists of two WFSTs called WFST-OCR and WFST-Lexicon. WFST-OCR handles the multiple hypotheses caused by erroneous text location, character segmentation and character recognition processes. The following WFST-Lexicon and its convolution of WFST-OCR resolve the hypotheses. The WFSTs integrate the conventional OCR and post-processing processes into one process. The benefit from the proposed method is that all the ambiguities are held as WFST data, and solved in one integrated step, the system outputs texts that are statistically consistent with regard to segmentation possibilities and the given language model. An experimental system demonstrates practical performance in spite of the hypothesis complexity inherent in the ICDAR test set and Kanji character texts.
Artificial Surface Tension to Stabilize Captured Shockwaves

This paper proposes (yet another) method for ameliorating the tendency of many Euler and Navier-Stokes codes to produces anomalous captured shockwaves at very high Mach numbers. The proposal is at the PDE level, and therefore in principle applicable to any type of grid. It is based on an analogy with surface tension.
Modeling Non-Equilibrium Dynamics and Saturable Absorption Induced by Free Electron Laser Radiation

Currently available X-ray and extreme ultraviolet free electron laser (FEL) sources provide intense ultrashort photon pulses. Those sources open new exciting perspectives for experimental studies of ultrafast non-equilibrium processes at the nanoscale in condensed matter. Theoretical approaches and computer simulations are being developed to understand the complicated dynamical processes associated with the interaction of FEL pulses with matter. In this work, we present the results of the application of a simplified three-channel model to the non-equilibrium dynamics of ultrathin aluminum films excited by FEL radiation at 33.3, 37 and 92 eV photon energy. The model includes semi-classical rate equations coupled with the equation of propagation of the photon wave packets. X-ray transmission measurements are found to be in agreement with present simulations, which are also able to shed light on temporal dynamics (in the fs range) in nano-sized Al films strongly interacting with the photon pulse. We also expanded our non-linear model, explicitly including the two-photon absorption cross-section and the effect of including electron heating for reproducing transmission measurements.
Shaping loyalty

Creating custom tools is crucial for accelerating, linking, and deepening various design-research and innovation activities. It is an exciting time for design researcli. Many companies in the service sector (e.g.*, healthcare, insurances companies) are striving to gain a competitive advantage by finding ways to improve the customer experience or by adjusting products or services to dynamically changing contexts of use. There is a need to step beyond the traditional way of developing products and services. Consequently, there is a perfect space for design researchers to step into: supporting the business community in understanding people in the context of their everyday lives to create products and services that respond to their needs. To explore how companies can learn from the design research approach, we—a team of five design researchers
Large Scale Clinical Text Processing and Process Optimization

and Objective This tutorial outlines the benefits and challenges of processing large volumes of clinical text with natural language processing (NLP). As NLP becomes more available and is able to tackle more complex problems, the ability to scale to millions of clinical notes must be considered. The Department of Veterans Affairs (VA) has more than 2 billion clinical notes has developed NLP libraries to be able to apporach projects of that scale. Participants will be introduced to existing tools and resources for large-scale NLP tasks, including Unstructured Information Management Architecture Asynchronous Scaleout (UIMA AS), the VA Leo NLP libraries, and the JMX Analysis Module (JAM) monitoring tool. The methods of computational performance analysis will be described and process optimization solutions will be demonstrated. Participants will be walked through a scenario of creating and launching an asynchronous NLP pipeline, monitoring it for performance metrics and identifying bottlenecks, and redeploying the pipeline with an optimal configuration. The tutorial will be presented by two instructors involved in the development and use of Leo and JAM in the VA.
Laser-Based Measurements in Cell Biology Elliot

VOL. 82 0091 hts reserved. 81 DOI: 10.1016/S0091 -679X -679X A. T he Laser B. C oherency and Illumination Volume II. L aser-Based Imaging Methods A. L aser Scanning Confocal Microscopy B. M ultipoint Confocal Laser Microscopy C. T otal Internal Reflection Microscopy D. N onlinear Imaging E. S uper Resolution Microscopy III. M easurement of Cellular State: Molecular Parameters A. P hotobleaching Methods B. F luorescence Lifetime Imaging C. F luorescence Correlation Spectroscopy IV. S ummary R eferences
LCC-DCU C-C Question Answering Task at NTCIR-5

This paper describes the work for our participation in the NTCIR-5 Chinese to Chinese Question Answering task. Our strategy is based on the “Retrieval plus Extraction” approach. We first retrieve relevant documents, then retrieve short passages from the above documents, and finally extract named entity answers from the most relevant passages. For question type identification, we use simple heuristic rules which can cover most questions. The Lemur toolkit with the OKAPI model is used for document retrieval. Results of our task submission are given and some preliminary conclusions drawn.
Target payments in primary care: effects on professional practice and health care outcomes.

BACKGROUND The method by which physicians are paid may affect their professional practice. Although payment systems may be used to achieve policy objectives (e.g. improving quality of care, cost containment and recruitment to under-served areas), little is known about the effects of different payment systems in achieving these objectives. Target payments are a payment system which remunerate professionals only if they provide a minimum level of care. OBJECTIVES To evaluate the impact of target payments on the professional practice of primary care physicians (PCPs) and health care outcomes. SEARCH STRATEGY We searched the Cochrane Effective Practice and Organisation of Care Group specialised register; the Cochrane Controlled Trials Register; MEDLINE (1966 to October 1997); BIDS EMBASE (1980 to October 1997); BIDS ISI (1981 to October 1997); EconLit (1969 to October 1997); HealthStar (1975 to October 1997) Helmis (1984 to October 1997); health economics discussion paper series of the Universities of York, Aberdeen, Sheffield, Bristol, Brunel, and McMaster; Swedish Institute of Health Economics; RAND corporation; and reference lists of articles. SELECTION CRITERIA Randomised trials, controlled before and after studies and interrupted time series analyses of interventions comparing the impact of target payments to primary care professionals with alternative methods of payment, on patient outcomes, health services utilisation, health care costs, equity of care, and PCP satisfaction with working environment. DATA COLLECTION AND ANALYSIS Two reviewers independently extracted data and assessed study quality. MAIN RESULTS Two studies were included involving 149 practices. The use of target payments in the remuneration of PCPs was associated with improvements in immunisation rates, but the increase was statistically significant in only one of the two studies. REVIEWER'S CONCLUSIONS The evidence from the studies identified in this review is not of sufficient quality or power to obtain a clear answer to the question as to whether target payment remuneration provides a method of improving primary health care. Additional efforts should be directed in evaluating changes in physicians' remuneration systems. Although it would not be difficult to design a randomised controlled trial to evaluate the impact of such payment systems, it would be difficult politically to conduct such trials.
Evaluating Alternative Risk Adjusters for Medicare

In this study the authors use 3 years of the Medicare Current Beneficiary Survey (MCBS) to evaluate alternative demographic, survey, and claims-based risk adjusters for Medicare capitation payment. The survey health-status models have three to four times the predictive power of the demographic models. The risk-adjustment model derived from claims diagnoses has 75-percent greater predictive power than a comprehensive survey model. No single model predicts average expenditures well for all beneficiary subgroups of interest, suggesting a combined model may be appropriate. More data are needed to obtain stable estimates of model parameters. Advantages and disadvantages of alternative risk adjusters are discussed.
Three-way junction conformation dictates self-association of phage packaging RNAs

ABSTRACT The packaging RNA (pRNA) found in the phi29 family of bacteriophage is an essential component of a powerful molecular motor used to package the phage's DNA genome into the capsid. The pRNA forms homomultimers mediated by intermolecular "kissing-loop" interactions, thus it is an example of the unusual phenomenon of a self-associating RNA that can form symmetric higher-order multimers. Previous research showed the pRNAs from phi29 family phages have diverse self-association properties and the kissing-loop interaction is not the sole structural element dictating multimerization. We found that a 3-way junction (3wj) within each pRNA, despite not making direct intermolecular contacts, plays important roles in stabilizing the intermolecular interactions and dictating the size of the multimer formed (dimer, trimer, etc.). Specifically, the 3wj in the pRNA from phage M2 appears to favor a different conformation compared to the 3wj in the phi29 pRNA, and the M2 junction facilitates formation of a higher-order multimer that is more thermostable. This behavior provides insights into the fundamental principles of RNA self-association, and additionally may be useful to engineer fine-tuned properties into pRNAs for nanotechnology.
The tunnel source MOSFET: A novel asymmetric device solution for ultra-low power applications

With aggressive MOSFET scaling, short channel effects (DIBL and VTH roll-off), off-state and gate leakage, parasitic capacitance and resistance severely limit the device performance. These, in addition to VDD scaling limitation and high sub-threshold swing (≫60mv/dec) give rise to high IOFF and make power dissipation, both dynamic and static, an enormous challenge, especially for low power/low current applications. New device innovations are essential to achieve low IOFF by having steep sub-threshold behavior for low power applications. Towards this end, a novel asymmetric Tunneling Source MOSFET is proposed in this paper. The main feature of this device is the concept of gate controlled carrier injection through band-to-band tunneling at the source junction. This novel device has the potential for steep sub-threshold behavior (≪60mv/dec), improved ION/IOFF and high ROUT and gain (gm × ROUT) at low bias currents. It also possesses excellent immunity against short channel effects which improves scalability into sub-50nm regime and makes it an attractive candidate for low power digital and analog operations.
Ground-state properties of rare-earth metals: an evaluation of density-functional theory

The rare-earth metals have important technological applications due to their magnetic properties, but are scarce and expensive. Development of high-performance magnetic materials with less rare-earth content is desired, but theoretical modeling is hampered by complexities of the rare earths electronic structure. The existence of correlated (atomic-like) 4f electrons in the vicinity of the valence band makes any first-principles theory challenging. Here, we apply and evaluate the efficacy of density-functional theory for the series of lanthanides (rare earths), investigating the influence of the electron exchange and correlation functional, spin-orbit interaction, and orbital polarization. As a reference, the results are compared with those of the so-called ‘standard model’ of the lanthanides in which electrons are constrained to occupy 4f core states with no hybridization with the valence electrons. Some comparisons are also made with models designed for strong electron correlations. Our results suggest that spin–orbit coupling and orbital polarization are important, particularly for the magnitude of the magnetic moments, and that calculated equilibrium volumes, bulk moduli, and magnetic moments show correct trends overall. However, the precision of the calculated properties is not at the level of that found for simpler metals in the Periodic Table of Elements, and the electronic structures do not accurately reproduce x-ray photoemission spectra.
Surcoût de l'authentification et du consensus dans la sécurité des réseaux sans fil véhiculaires. (Authentication and Consensus Overhead in Vehicular Ad Hoc Networks)

Les reseaux ad hoc sans fil vehiculaires (VANET) permettent les communications entre vehicules afin d'augmenter la securite routiere et d'agrementer l'experience de conduite. Une categorie d'applications ayant suscite un fort interet est celle liee a la securite du trafic routier. Un exemple prometteur est l'alerte de danger local qui permet d'accroitre la " ligne de vue " du conducteur en lui proposant un ensemble d'alertes afin d'anticiper des situations potentiellement dangereuses. En raison de leurs contraintes temporelles fortes et les consequences critiques d'une mauvaise utilisation, il est primordial d'assurer des communications securisees. Mais l'ajout de services de securite entraine un surcout de calcul et reseau. C'est pourquoi l'objectif de notre travail est d'etablir un cadre general (de maniere analytique) du surcout de la securite sur le delai de transfert d'une alerte. Parmi les mecanismes de securite conventionnels, le service d'authentification apparait comme la pierre angulaire de la securite des VANETs. De plus, l'authentification est utilisee pour chaque message emis ou recu. Il est donc potentiellement le service le plus consommateur. C'est pourquoi, nous nous focalisons sur ce service. Nous nous posons ainsi les questions suivantes : quel est le cout de l'authentification ? Quel est son impact sur l'application d'alerte de danger local ? La premiere contribution de cette these est l'elaboration d'une formule permettant le calcul du surcout de la signature numerique. Mais l'authentification ne sera pas le seul mecanisme de securite deploye. Le consensus est notamment un des mecanismes frequemment employes afin d'instaurer une confiance entre les vehicules. En effet, grâce a une methode de decision et a partir d'un ensemble de messages, le consensus vise a obtenir un commun accord sur une valeur ou une action entre les vehicules. Ainsi, nous devons comprendre comment definir les parametres de consensus afin de reduire l'impact de ce mecanisme sur le delai et la distance de freinage ? Comment s'integre le consensus dans la formule globale de surcout de l'authentification ? C'est notamment a ces questions que cette these repond. Notre deuxieme contribution est une methode de decision dynamique qui analyse l'environnement reseau courant (nombre de voisins a portee de communication), et explore le contenu des alertes. Il en resulte une reduction du nombre de paquets a examiner et donc une reaction plus rapide et plus adaptee a l'alerte.
Elaborative encoding through self-generation enhances outcomes with errorless learning: Findings from the Skypekids memory study

Errorless learning has demonstrated efficacy in the treatment of memory impairment in adults and older adults with acquired brain injury. In the same population, use of elaborative encoding through supported self-generation in errorless paradigms has been shown to further enhance memory performance. However, the evidence base relevant to application of both standard and self-generation forms of errorless learning in children is far weaker. We address this limitation in the present study to examine recall performance in children with brain injury (n = 16) who were taught novel age-appropriate science and social science facts through the medium of Skype. All participants were taught these facts under conditions of standard errorless learning, errorless learning with self-generation, and trial-and-error learning after which memory was tested at 5-minute, 30-minute, 1-hour and 24-hour delays. Analysis revealed no main effect of time, with participants retaining most information acquired over the 24-hour testing period, but a significant effect of condition. Notably, self-generation proved more effective than both standard errorless and trial-and-error learning. Further analysis of the data revealed that severity of attentional impairment was less detrimental to recall performance under errorless conditions. This study extends the literature to provide further evidence of the value of errorless learning methods in children with ABI and the first demonstration of the effectiveness of self-generation when delivered via the Internet.