Miracle-dz/UniFAR-FTUs huggingface dataset:
Word-context effects in word naming and lexical decision

Stanovich and West (1983; West and Stanovich, 1982) demonstrated that lexical decisions to target words preceded by incongruous sentence contexts are inhibited more by these contexts than are naming responses to the same target words. They argued that this difference between the two tasks was due to post-lexical processing at the message level that is effective only in the lexical-decision task. The operations of the mechanism thought to underlie this post-lexical effect also predict that, under certain circumstances, the processing of target words congruous with the sentence context should be facilitated more in lexical decision than in naming. The present naming study together with an earlier lexical-decision study tested and confirmed this prediction for word targets following word contexts. The stimulus-onset asynchrony of context word and target word was also varied. This manipulation clearly affected the magnitude of facilitation, indicating that context-induced attentional processing can facilitate.
Demonstration of 10k Gate-Scale Adiabatic-Quantum-Flux-Parametron Circuits

Adiabatic quantum flux parametron (AQFP) is a very energy-efficient superconductor logic. In AQFP logic, dynamic energy dissipation can be drastically reduced due to adiabatic switching operations using ac excitation currents. In the present study, we evaluated circuit yields using a large-scale AQFP circuit composed of as many as 10,000 AQFP gates with approximately 20,000 Josephson junctions. We measured eleven chips from four wafers and obtained circuit yields of 48% for 1,000-gate circuits and 22% for 10,000-gate circuits, respectively. In all the circuits, which worked correctly, the margins of excitation currents were as wide as approximately ±20%.
The clinical pathological characteristics and prognosis of FGFR1 gene amplification in non-small-cell lung cancer: a meta-analysis

FGFR1 amplification is recognized as a novel therapy target for non-small-cell lung cancer (NSCLC), especially in squamous cell carcinoma (SCC). However, the association between FGFR1 amplification and the clinicopathological characteristics of NSCLC remains controversial. We performed a meta-analysis of 17 eligible studies to examine the correlation between FGFR1 gene amplification and clinicopathological characteristics. FGFR1 amplification was closely related to these clinicopathological features, including sex (odds ratio [OR] 2.05, 95% confidence interval [CI] 1.50–2.80), smoking (OR 3.31, 95% CI 2.02–5.44), and histology (OR 3.60, 95% CI 2.82–4.59). FGFR1 amplification was associated with shorter overall survival, and no significant heterogeneity existed between studies (I2=3.8%). We should note that publication bias may partly account for these results, but our findings remained significant after the trim-and-fill method (hazard ratio 1.22, 95% CI 1.06–1.40). However, no significant correlation was found with poor disease-free survival (hazard ratio 1.43, 95% CI 0.96–2.12). In conclusion, this study showed that FGFR1 amplification was significantly associated with sex, smoking, and histology. FGFR1 amplification could be a marker of poor prognosis in NSCLC patients, especially in SCC patients.
The ROOT DETERMINED NODULATION 1 Gene Regulates Nodule Number in Roots of Medicago truncatula and Defines a Highly Conserved , Uncharacterized Plant Gene Family 1 [ C ] [ W ] [ OA ]

The formation of nitrogen-fixing nodules in legumes is tightly controlled by a long-distance signaling system in which nodulating roots signal to shoot tissues to suppress further nodulation. A screen for supernodulating Medicago truncatula mutants defective in this regulatory behavior yielded loss-of-function alleles of a gene designated ROOT DETERMINED NODULATION1 (RDN1). Grafting experiments demonstrated that RDN1 regulatory function occurs in the roots, not the shoots, and is essential for normal nodule number regulation. The RDN1 gene, Medtr5g089520, was identified by genetic mapping, transcript profiling, and phenotypic rescue by expression of the wild-type gene in rdn1 mutants. A mutation in a putative RDN1 ortholog was also identified in the supernodulating nod3 mutant of pea (Pisum sativum). RDN1 is predicted to encode a 357-amino acid protein of unknown function. The RDN1 promoter drives expression in the vascular cylinder, suggesting RDN1 may be involved in initiating, responding to, or transporting vascular signals. RDN1 is a member of a small, uncharacterized, highly conserved gene family unique to green plants, including algae, that we have named the RDN family.
A distributed spoken user interface based on open agent architecture (OAA)

The paper describes a spoken user interface that can be distributed over a network and that allows the user to have voice access to various functions such as user authentication, command controls in web browser and personal or public information retrieval. Integration of the user interface system is accomplished by using the Open Agent Architecture. A detailed description of the distributed speech recognizer used in the interface is also provided.
Music Therapy for the Pediatric Patient Experiencing Agitation During Posttraumatic Amnesia: Constructing a Foundation From Theory

Posttraumatic amnesia can be a clinically difficult phase to manage in the pediatric patient emerging from coma following severe traumatic brain injury (TBI), as agitation is a common presentation during this stage of recovery. Familiar song is offered, as a music therapy intervention, to reduce agitation for the pediatric patient; however, there is a paucity of evidence to support this. The purpose of this article is to combine interrelated knowledge from the fields of pediatric TBI recovery, music therapy, music neuropsychology, and mother–infant musicality to construct a theoretical foundation for the use of familiar song with this population.
Rhythm and Vowel Quality in Accents of English

Rhythm and Vowel Quality in Accents of English In a sample of 27 speakers of Scottish Standard English two notoriously variable consonantal features are investigated: the contrast of /m/ and /w/ and non-prevocalic /r/, the latter both in terms of its presence or absence and the phonetic form it takes, if present. The pattern of realisation of non-prevocalic /r/ largely confirms previously reported findings. But there are a number of surprising results regarding the merger of /m/ and /w/ and the loss of non-prevocalic /r/: While the former is more likely to happen in younger speakers and females, the latter seems more likely in older speakers and males. This is suggestive of change in progress leading to a loss of the /m/ - /w/ contrast, while the variation found in non-prevocalic /r/ follows an almost inverse sociolinguistic pattern that does not suggest any such change and is additionally largely explicable in language-internal terms. One phenomenon requiring further investigation is the curious effect direct contact with Southern English accents seems to have on non-prevocalic /r/: innovation on the structural level (i.e. loss) and conservatism on the realisational level (i.e. increased incidence of [r] and [r]) appear to be conditioned by the same sociolinguistic factors.
Accuracy between optical and inertial motion capture systems for assessing trunk speed during preferred gait and transition periods

Abstract Motion capture through inertial sensors is becoming popular, but its accuracy to describe kinematics during changes in walking speed is unknown. The aim of this study was to determine the accuracy of trunk speed extracted using an inertial motion system compared to a gold standard optical motion system, during steady walking and stationary periods. Eleven participants walked on pre-established paths marked on the floor. Between each lap, a 1-second stationary transition period at the initial position was included prior to the next lap. Resultant trunk speed during the walking and transition periods were extracted from an inertial (240 Hz sampling rate) and an optical system (120 Hz sampling rate) to calculate the agreement (Pearson’s correlation coefficient) and relative root mean square errors between both systems. The agreement for the resultant trunk speed between the inertial system and the optical system was strong (0.67 < r ≤ 0.9) for both walking and transition periods. Moreover, relative root mean square error during the transition periods was greater in comparison to the walking periods (>40% across all paths). It was concluded that trunk speed extracted from inertial systems have fair accuracy during walking, but the accuracy was reduced in the transition periods.
The Closed Topological Vertex via the Cremona Transform

We compute the local Gromov-Witten invariants of the "closed vertex", that is, a configuration of three P 1 's meeting in a single triple point in a Calabi-Yau threefold. The method is to express the local invariants of the vertex in terms of ordinary Gromov-Witten invariants of a certain blowup of P 3 and then to compute those invariants via the geometry of the Cremona transformation.
Design of nonlinear flight control law for a tailless unmanned aerial vehicle

The active disturbance rejection control (ADRC) techniques based on nonlinear dynamic inversion (NDI) method were proposed for a tailless unmanned aerial vehicle nonlinear flight control law design problem. The dynamics to be controlled were separated into two groups. For each group the corresponding control loop could be designed and the integrated controller was constructed by cascading them. The controller was compared with classic NDI method and shown to yield better performance in terms of disturbance rejection and robustness capabilities. Simulation results also showed the controller designed from one equilibrium condition could perform excellently in large flight envelope.
Are we far from correctly inferring gene interaction networks with Lasso?

Detecting the interactions of genetic compounds like genes, SNPs, proteins, metabolites, etc. can potentially unravel the mechanisms behind complex traits and common genetic disorders. Several methods have been taken into consideration for the analysis of different types of genetic data, regression being one of the most widely adopted. Without any doubt, a common data type is represented by gene expression profiles, from which gene regulatory networks have been inferred with different approaches. In this work we review nine penalised regression methods applied to microarray data to infer the topology of the network of interactions. We evaluate each method with respect to the complexity of biological data. We analyse the limitations of each of them in order to suggest a number of precautions that should be considered to make their predictions more significant and reliable.
Estimation of Arterial Stiffness, Compliance, and Distensibility From M‐Mode Ultrasound Measurements of the Common Carotid Artery

Background and Purpose Arterial stiffness may indicate early vascular changes that predispose to the development of major vascular disease. The repeatability of a variety of indices of arterial stiffness calculated from a standard carotid arterial M-mode ultrasound image was investigated. Methods Twenty-six asymptomatic normal subjects were imaged and had blood pressure recordings on each of two separate occasions at least 1 day apart. Using a computer-assisted method, the maximum and minimum internal diameter and average wall thickness of the right common carotid artery were measured over several cardiac cycles, and the following indices of arterial stiffness and distensibility (compliance) were derived: the pressure-strain elastic modulus (Ep), Young's modulus (E), cross-sectional compliance (CC), and the distensibility coefficient (DC). Results The repeatability of these measures, expressed as coefficients of variation, was as follows: Ep, 18%; E, 24%; CC, 14%; and DC, 13%. In another group of 20 subjects, the coefficient of variation for repeat examination by different sonographers was Ep, 19%; E, 20%; CC, 14%; and DC, 17% and for the one sonographer using two ultrasound machines was Ep, 13%; E, 13%; CC, 11%; and DC, 13%. These values indicate a moderate level of repeatability. In a univariate analysis each of these indices was significantly related to increasing age (Ep=1.0+12.9×AGE, r=.80; E=314.5 +13.9×AGE, r=.48; CC=22.6−0.26×AGE, r=−.63; DC=64.0−0.65×AGE, r=−.78) but not to wall thickness (all P > .47). Using multiple regression techniques to adjust for age, wall thickness is a significant predictor of distensibility (P=.017), cross-sectional compliance (P < .001), and the pressure-strain elastic modulus (P=.019). Because Young's modulus is calculated from wall thickness, it could not be included in the multivariate analysis. Conclusions We conclude that estimates of carotid artery distensibility and cross-sectional compliance derived from M-mode ultrasound recordings are moderately repeatable and may provide useful additional end points for trials of atherosclerotic progression.
Multi-agent ant system for redundancy allocation problem of multi states power system

This paper considers a redundancy allocation problem for a multi-state power system. This type of problems involves selection of components with multiple choices and redundancy levels that produce maximum benefits, subject to the system availability and demand constraints. The presented multi agent ant system finds the optimal system topology by choosing system elements from a list of available equipments. Each element is characterized by its productivity, availability and cost. The objective is to minimize the total investment costs while satisfying both system availability and demand constraints. The procedure based on the generalized Ushakovpsilas technique is used for evaluation of the system availability. Illustrative examples demonstrate how to obtain the optimal structures of the power system for different system availability constraints.
High-Density Lipoprotein Cholesterol Is a Favorable Prognostic Factor and Negatively Correlated with C-Reactive Protein Level in Non-Small Cell Lung Carcinoma

Background Although the alterations of lipid profile in lung cancer have been documented, the prognostic value of serum HDL-C level and its correlation with inflammation in NSCLC remain unknown. Subjects and Methods Levels of preoperative serum lipid concentrations (including HDL-C, LDL-C, TC, and TG) and the inflammatory biomarker C-reactive protein level (CRP) were retrospectively analyzed in 228 patients with NSCLC and in 300 healthy controls. The serum lipid levels in these two populations were compared. Univariate and multivariate cox hazards analyses were performed to investigate the prognostic value of serum lipid levels in NSCLC. The correlation between CRP and lipid profile were also analyzed. Results Compared with those in normal controls, the serum HDL-C, LDL-C, and TC levels were statistically decreased and the TG levels were significantly increased in 228 NSCLC patients. The patients with decreased levels of HDL-C had significantly lower 5-year survival rates than those with normal HDL-C, not only in the whole NSCLC cohort but also in the subgroups stratified according to the disease T, N classifications, and metastasis, whereas the other lipid components were not independent prognostic factors for NSCLC. Of the lipid components, a lower HDL-C level was observed more often in patients with a high CRP level than in those with a normal CRP level. Spearman’s rank correlation analysis revealed that the HDL-C level presented a negative correlation with the CRP level (r = −0.360, p<0.001). Conclusions A decreased level of preoperative HDL-C was found to be associated with poor survival in patients with NSCLC. Serum HDL-C level may be a clinical prognosis factor for NSCLC patients. In addition, a negative correlation was present between the levels of HDL-C and CRP, the well-known inflammation biomarker.
Coverage Analysis for Millimeter Wave Networks: The Impact of Directional Antenna Arrays

Millimeter wave (mm-wave) communications is considered a promising technology for 5G networks. Exploiting beamforming gains with large-scale antenna arrays to combat the increased path loss at mm-wave bands is one of the defining features. However, previous works on mm-wave network analysis usually adopted oversimplified antenna patterns for tractability, which can lead to significant deviation from the performance with actual antenna patterns. In this paper, using tools from stochastic geometry, we carry out a comprehensive investigation on the impact of directional antenna arrays in mm-wave networks. We first present a general and tractable framework for coverage analysis with arbitrary distributions for interference power and arbitrary antenna patterns. It is then applied to mm-wave ad hoc and cellular networks, where two sophisticated antenna patterns with desirable accuracy and analytical tractability are proposed to approximate the actual antenna pattern. Compared with previous works, the proposed approximate antenna patterns help to obtain more insights on the role of directional antenna arrays in mm-wave networks. In particular, it is shown that the coverage probabilities of both types of networks increase as a non-decreasing concave function with the antenna array size. The analytical results are verified to be effective and reliable through simulations, and numerical results also show that large-scale antenna arrays are required for satisfactory coverage in mm-wave networks.
Human Cyclin K, a Novel RNA Polymerase II-Associated Cyclin Possessing Both Carboxy-Terminal Domain Kinase and Cdk-Activating Kinase Activity

ABSTRACT The gene coding for human cyclin K was isolated as aCPR (cell-cycle progression restoration) gene by virtue of its ability to impart a Far− phenotype to the budding yeast Saccharomyces cerevisiae and to rescue the lethality of a deletion of the G1 cyclin genes CLN1,CLN2, and CLN3. The cyclin K gene encodes a 357-amino-acid protein most closely related to human cyclins C and H, which have been proposed to play a role in regulating basal transcription through their association with and activation of cyclin-dependent kinases (Cdks) that phosphorylate the carboxyl-terminal domain (CTD) of the large subunit of RNA polymerase II (RNAP II). Murine and Drosophila melanogaster homologs of cyclin K have also been identified. Cyclin K mRNA is ubiquitously expressed in adult mouse and human tissues, but is most abundant in the developing germ cells of the adult testis and ovaries. Cyclin K is associated with potent CTD kinase and Cdk kinase (CAK) activity in vitro and coimmunoprecipitates with the large subunit of RNAP II. Thus, cyclin K represents a new member of the “transcription” cyclin family which may play a dual role in regulating Cdk and RNAP II activity.
Oligodendrocyte Development and the Onset of Myelination in the Human Fetal Brain

Oligodendrocytes are cells that myelinate axons, providing saltatory conduction of action potentials and proper function of the central nervous system. Myelination begins prenatally in the human, and the sequence of oligodendrocyte development and the onset of myelination are not thoroughly investigated. This knowledge is important to better understand human diseases, such as periventricular leukomalacia, one of the leading causes of motor deficit in premature babies, and demyelinating disorders such as multiple sclerosis (MS). In this review we discuss the spatial and temporal progression of oligodendrocyte lineage characterized by the expression of specific markers and transcription factors in the human fetal brain from the early embryonic period (5 gestational weeks, gw) until midgestation (24 gw). Our in vitro evidence indicated that a subpopulation of human oligodendrocytes may have dorsal origin, from cortical radial glia cells, in addition to their ventral telencephalic origin. Furthermore, we demonstrated that the regulation of myelination in the human fetal brain includes positive and negative regulators. Chemokines, such as CXCL1, abundant in proliferative zones during brain development and in regions of remyelination in adult, are discussed in the view of their potential roles in stimulating oligodendrocyte development. Other signals are inhibitory and may include, but are not limited to, polysialic acid modification of the neural cell adhesion molecule on axons. Overall, important differences in temporal and spatial distribution and regulatory signals for oligodendrocyte differentiation exist between human and rodent brains. Those differences may underlie the unique susceptibility of humans to demyelinating diseases, such as MS.
Intelligent, Attractive, Well-Behaving, Unhappy: The Structure of Adolescents' Self-Concept and Its Relations to Their Social Behavior.

The self-concept (SC) structures of adolescent girls and boys were examined and related to their social behavior in situations of bullying. The participants were 281 eighth-grade adolescents, aged 14 to 15 years, from 15 school classes. The measures used were the Participant Role Questionnaire and an applied version of the Piers-Harris Children's Self-Concept Scale. A cluster analysis was performed to form groups with similar SC profiles. The ultimate solution consisted of six clusters, which differed significantly from each other in how much their members tended to bully others, assist the bully, reinforce the bully, and withdraw from bullying situations. Adolescents who tended to bully others typically had high social and physical SC, although their view of themselves was rather negative on the other SC domains. Youngsters who tended to assist or reinforce the bully either had an SC structure similar to that of the bullies, or they scored low on all SC domains. Withdrawing from bullying situations was m.
Affect, Moral Intuition, and Risk

The natural way to deal with moral issues involving risk is to rely on our intuitive feelings. “How bad is it? Well, how bad does it feel? ” We can also rely on reason to determine right and wrong but, as Jonathan Haidt has demonstrated, intuition comes first and dominates our responses unless we make an effort to critique and, if necessary, override it. We argue that our intuitive feelings are insensitive to large losses of life and thus mislead us in the face of natural disasters or human disasters associated with poverty, disease, and violence. Our intuitions seduce us into calmly turning away from these catastrophes, when we should be driven by outrage or sorrow to act. We propose ways to overcome this insensitivity through new forms of education and communication coupled with reliance on moral deliberation aimed at designing laws and institutions that compel attention to such problems.
Trust in the team leader: operationalization of the construct in an R&D context

Purpose – The aim of this paper is to suggest an instrument to measure trust in a team leader, within an R&D context.Design/methodology/approach – The material was collated from available literature and semi‐structured interviews. A total of 192 valid answers were collected from scientists and professionals working in R&D teams in Portugal.Findings – The factor analysis allowed for the extraction of four components: “integrity”, “benevolence”, “concern”, and “ability”. Research limitations/implications – The paper suggests the need to test the validity of the measuring tool in other contexts.Originality/value – A new measurement instrument for trust in the team leader is developed in the context of R&D teams.