Miracle-dz/UniFAR-FTUs huggingface dataset:
Incorporating supportive care into routine cancer care: the benefits and challenges to clinicians' practice.

PURPOSE/OBJECTIVES To investigate clinicians' experiences with supportive care screening and referral, and identify perceived barriers and benefits associated with implementation into the clinical setting. DESIGN Qualitative, exploratory approach based on interviews. SETTING A large regional hospital in Victoria, Australia, that provides chemotherapy and radiotherapy services to patients with cancer. SAMPLE 5 chemotherapy nurses and 1 radiation therapist. METHODS Semistructured interviews were conducted, documented, and analyzed with qualitative techniques. MAIN RESEARCH VARIABLES Clinical benefits of supportive care screening and referral, and barriers to clinical implementation. FINDINGS Clinicians perceived that supportive care screening benefited their practice by improving communication and rapport with patients. Clinicians supported each other during screening implementation, and although they initially were hesitant about the process, they ultimately endorsed screening for wider implementation. Time constraints and scope of practice were identified as significant barriers. CONCLUSIONS Supportive care screening was endorsed as part of future clinical practice, but barriers to implementation need to be addressed. IMPLICATIONS FOR NURSING With current psychosocial guidelines recommending routine supportive care screening of patients with cancer and statewide mandatory screening targets set in Australia, healthcare organizations need to carefully consider implementation processes. Although nurses are ideally placed to complete screening, organizations need to ensure that appropriate training and support mechanisms have been developed, as well as adequate resources, to enable integration into routine practice.
LBP-SVD Based Copy Move Forgery Detection Algorithm

With the extensive use of sophisticated image editing software, it has become easy to manipulate digital images without any visually visible clue. Copy-move is a special type of image forgery performed by copying a part of the image and pasting anywhere else in the same image. We proposed a passive image authentication technique to determine the copy-move forgery. First, the method divides the image into overlapping blocks. It use LBP (Local Binary Pattern) to label each block. Then, the biggest N of SVD values are extracted on the labeled blocks. N SVD values plus average Y, Cb, Cr values constitutes the feature vector for the block. Finally, the feature vectors are lexicographically sorted and element-by-element similarity measurement is used to determine the forged blocks. Experiment results demonstrate commendable performance in image copy-move forgery detection.
Household Indebtedness: How global and Domestic Macro-economic Factors Influence Credit Card Debt Default in Malaysia

Malaysia has one of the highest household debts relative to gross domestic product in the Asia region. High indebted households have negative net worth and prone to default even during mild shocks. In most economies including Malaysia, household loan default is dominated by mortgages. In Malaysia, however, credit card debt default rate has been growing faster than mortgage default rate. Thus, this paper analyses how combined global and domestic macroeconomic factors impact on credit card nonperforming loan (NPLs) in Malaysia. Estimates from the Autoregressive Distributed Lags (ARDL) model highlights that in the long run, credit card NPLs are procyclical as strong domestic real output reduces credit card default. The study shows positive global crude oil price shocks reduces the credit card NPLs while a stressed global financial market condition has a reverse effect on credit card NPLs. Further, consumer price index negatively relates to credit card NPLs while monetary policy affects NPLs whereby a cut back of the overnight policy rate reduces credit card debt default.
Cytological Bone Marrow Cell Differential Counts and Morphologic Findings in Healthy Cynomolgus Monkeys (Macaca fascicularis) from Nonclinical Toxicology Studies

Cytological bone marrow evaluation is utilized in nonclinical toxicology studies to characterize hematopoietic effects when the combined interpretation of histologic and complete blood count data does not yield sufficient information. Results from cytological bone marrow examination should be interpreted in the context of variability observed in concurrent control animals with consideration of cytologist experience and historical/published data. Cytological bone marrow differential counts and cellular morphologic findings from 130 (66 male, 64 female) healthy control cynomolgus monkeys from nonclinical toxicology studies were retrospectively analyzed. Myeloid to erythroid (M:E) ratios and the percentage of total cells for each cell type were determined from differential cell count data. M:E ratios ranged from 0.6:1 to 2.3:1. Percentages of total granulocytic cells, total erythroid cells, and lymphocytes ranged from 26.6% to 60.6%, 25.7% to 52.2%, and 5.5% to 40.4%, respectively. Monocytes, plasma cells, mast cells, and mitotic figures were typically <1% of total cells. Notable morphologic findings included occasional giant neutrophilic metamyelocytes and band neutrophils, ring-shaped band neutrophil nuclei, metarubricyte nuclear blebbing and binucleation, multiple or nonfused megakaryocyte nuclei, and emperipolesis. These results represent cytological bone marrow findings from healthy control cynomolgus monkeys utilized in nonclinical toxicology studies and provide insight into expected background variability.
Is optic neuritis more benign than other first attacks in multiple sclerosis?

Optic neuritis presentations are thought to have a better prognosis. The aim of our study was to compare conversion to multiple sclerosis on the different topographies of CISs. We prospectively evaluated 320 patients with CISs (123 with optic neuritis, 78 with brainstem syndromes, 89 with spinal cord syndromes, and 30 with other topographies) who were observed for a median of 39 months. Patients underwent brain MRI within 3 months of their first attack and again 12 months later. Conversion to multiple sclerosis determined either clinically or by MRI was evaluated according to topography. Baseline MRI was normal in 49.2% of patients with optic neuritis compared with 24% in brainstem syndromes, 24% in spinal cord syndromes, and 18.5% in other syndromes. Optic neuritis behaved differently from the other CISs for lower conversion to clinically definite multiple sclerosis and smaller proportion of patients fulfilling MRI dissemination in space, time, or both. Nevertheless, when only patients with abnormal cranial MRI results at baseline were selected, no differences for clinical or MRI conversion were found. Optic neuritis has a smaller risk for conversion to multiple sclerosis. Nevertheless, MRI at baseline, not CIS topography, appears to be the crucial issue at multiple sclerosis presentation. Ann Neurol 2005;57:210–215
Land use conversion from tourist to residential

This work analyses the forces that drive the conversion of non-hotel tourist accommodation into residential use. For this purpose, a land use change model that considers spatial autocorrelation is proposed and applied to the tourist area of Maspalomas, in Gran Canaria, Spain, which has suffered an extraordinary process of residentialization in the last decade. The empirical model estimates the probability that a non-hotel accommodation resort (apartments/bungalows) located in this area closes its activity within a prefixed time period. Results show that the state of the neighbouring resorts influences on the probability of closure of the apartments/bungalows, as well as their specific typology and low quality. From these results, some recommendations are proposed about the strategies undertaken by the implied agents.
Aerobic and anaerobic starvation metabolism in methanotrophic bacteria

The capacity for anaerobic metabolism of endogenous and selected exogenous substrates in carbon- and energy-starved methanotrophic bacteria was examined. The methanotrophic isolate strain WP 12 survived extended starvation under anoxic conditions while metabolizing 10-fold less endogenous substrate than did parallel cultures starved under oxic conditions. During aerobic starvation, the cell biomass decreased by 25% and protein and lipids were the preferred endogenous substrates. Aerobic protein degradation (24% of total protein) took place almost exclusively during the initial 24 h of starvation. Metabolized carbon was recovered mainly as CO(inf2) during aerobic starvation. In contrast, cell biomass decreased by only 2.4% during anaerobic starvation, and metabolized carbon was recovered mainly as organic solutes in the starvation medium. During anaerobic starvation, only the concentration of intracellular low-molecular-weight compounds decreased, whereas no significant changes were measured for cellular protein, lipids, polysaccharides, and nucleic acids. Strain WP 12 was also capable of a limited anaerobic glucose metabolism in the absence of added electron acceptors. Small amounts of CO(inf2) and organic acids, including acetate, were produced from exogenous glucose under anoxic conditions. Addition of potential anaerobic electron acceptors (fumarate, nitrate, nitrite, or sulfate) to starved cultures of the methanotrophs Methylobacter albus BG8, Methylosinus trichosporium OB3b, and strain WP 12 did not stimulate anaerobic survival. However, anaerobic starvation of these bacteria generally resulted in better survival than did aerobic starvation. The results suggest that methanotrophic bacteria can enter a state of anaerobic dormancy accompanied by a severe attenuation of endogenous metabolism. In this state, maintenance requirements are presumably provided for by fermentation of certain endogenous substrates. In addition, low-level catabolism of exogenous substrates may support long-term anaerobic survival of some methanotrophic bacteria.
Relationship Between the Parenting Styles and Students' Educational Performance Among Iranian Girl High School Students, A Cross- Sectional Study.

INTRODUCTION Parenting styles are effective in the educational performance of their child. The present study aimed to investigate the relationship between the parenting styles and students' educational performance among Iranian girl high school students. MATERIALS AND METHODS In a cross-sectional survey, female students in high schools of Ilam (Iran) evaluated during the academic year 2014-15. Multistage cluster random sampling was used to select the participants. Data were collected by two demographic and Baumrind's parenting styles questionnaire. The Cronbach's alpha coefficient was measured as an index of internal identicalness of the questionnaire to verify its reliability. RESULTS A total 400 students were studied. The Mean±SD of the students' age were 14±1.08. The students' school grades were the first year of high school to pre-university course. The Mean±SD of parenting styles were 35.37±5.8, 34.69±6.34 and 19.17±6.64 for permissive parenting style, authoritarian parenting style and authoritative parenting styles, respectively. There was a significant relationship between the score of permissive parenting style (p= 0.001, r= 0.151), authoritarian parenting style (p= 0.001, r= 0.343) and authoritative parenting style (p=0. 001, r= 0.261) with the students' average score for studying. CONCLUSION The results of this study demonstrate that parental influence plays an important role in students' educational performance.
Prevalence and risk factors of the rural adult people prehypertension status in Liaoning Province of China.

BACKGROUND Prehypertension is a new category of blood pressure (BP) classification according to the Seventh Report of The Joint National Committee. Little is known about the epidemiology of prehypertension in rural China. The purpose of the present study is to determine the prevalence of prehypertension and associated risk factors in rural adult people of China. METHODS AND RESULTS Through cluster multistage and random sampling method, a resident group of 29,970 people aged > or =35 years old in Liaoning Province was selected from 2004 to 2005. The survey on BP and associated risk factors was carried out. Prehypertension was defined as systolic BP between 120 and 139 mmHg or diastolic BP 80 and 89 mmHg. Overall, the prevalence of prehypertension was 47.0%, males 51.2% and females 42.6%, respectively. The prevalence of hypertension was 36.2%. Multivariable logistic regression showed overweightness, obesity and drinking were risk factors of prehypertension. Female and greater than high school education status were shown as protective factors. CONCLUSIONS The prevalence of prehypertension of rural adult people in China is dramatically high and it was associated with many risk factors. Comprehensive lifestyle modifications are needed to be taken to decrease the incidence of prehypertension and to prevent prehypertension people from hypertension and cardiovascular disease.
Faith Profaned: The Religious Freedom Restoration Act and Religion in the Prisons

When Congress passed the Religious Freedom Restoration Act (RFRA)2 in 1993, it aimed to increase dramatically the level of protection for inmates' religious liberties, which had only received minimal judicial scrutiny in the past. RFRA was primarily a response to the 1990 case of Employment Division v. Smith,3 in which the Supreme Court refused to apply strict scrutiny review when generally applicable laws burdened religious practices. " In addition to resurrecting strict scrutiny for these cases, RFRA extended this heightened level of protection to the free exercise claims of prisoners. "We want religion in the prisons," declared Senator Orrin Hatch, one of the original sponsors of RFRA. "It is one of the best rehabilitative influences we can have. Just because they are prisoners does not mean all of their rights should go down the drain . Despite RFRA's apparent drastic change in the degree of protection for prisoners' religious rights cases, RFRA's stated level of scrutiny is not the controlling factor in the way many courts are deciding prisoners' free exercise cases. The reason stems from two tendencies that have plagued the history of the judiciary's involvement in this area of law and continue to exist under RFRA. First, many courts have failed to understand and evaluate prisoners'
BEYOND ACTIVATION REFORMING EUROPEAN UNEMPLOYMENT PROTECTION SYSTEMS IN POST-INDUSTRIAL LABOUR MARKETS

ABSTRACT Though activation has been a key theme in recent comparative scholarship on social policy, existing research has arguably failed to capture some important cross-national differences in the extent of welfare state adaptation it entails. Conceptualising activation as but one unemployment policy reform indicator alongside ‘unemployment support homogenisation’ and ‘unemployment policy co-ordination’, and empirically sketching reform trends in four European states, this article argues it is possible to identify a cleavage between countries where activation policies are part of an unambiguous adaptation of labour market policies to the emergent post-industrial economy, and countries in which similar trends of policy adaptation have been more constrained, hesitant and uneven. To account for this fracture it is necessary to understand the differing ways that conventional unemployment policies were institutionally articulated within national political economies, as this bears on the feasibility of a new paradigm of labour market regulation emerging.
A New Zealand study of association between crime and the state of the economy

The aim of this thesis is to investigate whether there are associations between economically motivated crimes and macroeconomic variables. Economically motivated crimes include burglary, fraud and theft. Non-traffic offences are used as the measurement of overall crime levels, and an association between non-traffic offences and macroeconomic variables is analysed as well. Forecasting the number of people charged with burglary, fraud, theft and non-traffic offences is another objective of this thesis. Association between economically motivated crimes and the unemployment rate is also analysed at a regional level. Methods used in this thesis include Vector Autoregressive (VAR) models, Vector Error Correction Models (VECM) and Autoregressive Integrated Moving Average (ARIMA) models. VECM and VAR models are used to produce Granger-Causality tests and impulse responses in order to summarise the associations between crimes and macroeconomic variables. All modelling methods are used to generate forecasts. The conclusion from this thesis is that there are associations between crime and some macroeconomic variables at a national level. The biggest impact on crime is its own value in the past. The impact of macroeconomic variables is minor, and this makes the sign of the impact less important. In fact, the sign of the impact is hard to conclude because it moves between positive and negative in different periods. At a national level, the growth rate of unemployment causes the growth rate of burglary, theft and non-traffic charges. The association between unemployment and crime becomes insignificant once all macroeconomic variables are included. Overall, the growth rate of personal weekly average income or household debt and disposable income ratio (both measuring personal or household financial condition) causes an increase in the growth rate of burglary, theft and non-traffic charges. Movement of inflation causes an increase in the growth rate of fraud charges. At a regional level, growth in the unemployment rate causes an increase in theft charges in Auckland and Northland. In Nelson/Marlborough/West Coast, growth in the unemployment rate causes growth in burglary charges and vice versa. Growth in the unemployment rate causes growth in the rate of fraud charges, but this is found in Northland only. Forecasts produced by this study suggest that the number of people charged with burglary, theft, fraud and non-traffic offences will continue to decrease up until 2019, but at a lower rate of reduction.
Adenosine A2A Receptor and Dopamine D3 Receptor Interactions: Evidence of Functional A2A/D3 Heteromeric Complexes

Adenosine A2A and dopamine D2 receptors have been shown previously to form heteromeric complexes and interact at the level of agonist binding, G protein coupling, and trafficking. Because dopamine D2 and D3 receptors show a high degree of sequence homology, A2A and D3 receptors may also interact in a similar manner. The present studies with confocal microscopy showed that A2A-yellow fluorescent protein (YFP) and D3-green fluorescent protein 2 (GFP2) receptors colocalize in the plasma membrane. Furthermore, fluorescence resonance energy transfer (FRET) analysis demonstrated that A2A-YFP and D3-GFP2 receptors give a positive FRET efficiency and are thereby likely to exist as heteromeric A2A/D3 receptor complexes. Saturation experiments with [3H]dopamine demonstrated that the A2A receptor agonist 4-[2-[[6-amino-9(N-ethyl-β-d-ribofuranuronaminoamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid (CGS-21680) reduced the affinity of the high-affinity agonist binding state of the D3 receptor for [3H]dopamine. The A2A and D2A receptors seem to interact also at the level of G protein coupling, because the adenosine A2A receptor agonist CGS-21680 fully counteracted the D3 receptor-mediated inhibition of a forskolin-mediated increase in cAMP levels. Taken together, when coexpressed in the same neuron, A2A and D3 receptors seem to form A2A/D3 heteromeric receptor complexes in which A2A receptors antagonistically modulate both the affinity and the signaling of the D3 receptors. D3 receptor is one of the therapeutic targets for treatment of schizophrenia, and therefore, the A2A/D3 receptor interactions could provide an alternative antischizophrenic treatment.
What Determines Lean Manufacturing Implementation? A CB-SEM Model

This research aims to ascertain the determinants of effective Lean Manufacturing (LM). In this research, Covariance-based Structural Equation Modeling (CB-SEM) analysis will be used in order to analyze the determinants. Through CB-SEM analysis, the significant key determinants can be determined and the direct relationships among determinants can be analyzed. Thus, the findings of this research can act as guidelines for achievement of LM effectiveness, not only providing necessary steps for successful implementation of lean, but also helping lean companies to achieve higher level of lean cost and time savings.
Exact mean-energy expansion of Ginibre's gas for coupling constants Γ=2×(oddinteger).

Using the approach of a Vandermonde determinant to the power Γ=Q^{2}/k_{B}T expansion on monomial functions, a way to find the excess energy U_{exc} of the two-dimensional one-component plasma (2DOCP) on hard and soft disks (or a Dyson gas) for odd values of Γ/2 is provided. At Γ=2, the present study not only corroborates the result for the particle-particle energy contribution of the Dyson gas found by Shakirov [Shakirov, Phys. Lett. A 375, 984 (2011)10.1016/j.physleta. 2011.01. 004] by using an alternative approach, but also provides the exact N-finite expansion of the excess energy of the 2DOCP on the hard disk. The excess energy is fitted to the ansatz of the form U_{exc}=K^{1}N+K^{2}sqrt[N]+K^{3}+K^{4}/N+O(1/N^{2}) to study the finite-size correction, with K^{i} coefficients and N the number of particles. In particular, the bulk term of the excess energy is in agreement with the well known result of Jancovici for the hard disk in the thermodynamic limit [Jancovici, Phys. Rev. Lett. 46, 386 (1981)10.1103/PhysRevLett.46. 386]. Finally, an expression is found for the pair correlation function which still keeps a link with the random matrix theory via the kernel in the Ginibre ensemble [Ginibre, J. Math. Phys. 6, 440 (1965)10.1063/1.1704292] for odd values of Γ/2. A comparison between the analytical two-body density function and histograms obtained with Monte Carlo simulations for small systems and Γ=2,6,10,. shows that the approach described in this paper may be used to study analytically the crossover behavior from systems in the fluid phase to small crystals.
Tolerance of Sir1p/Origin Recognition Complex-Dependent Silencing for Enhanced Origin Firing at HMRa

ABSTRACT The HMR-E silencer is a DNA element that directs the formation of silent chromatin at the HMR a locus in Saccharomyces cerevisiae. Sir1p is one of four Sir proteins required for silent chromatin formation at HMR a. Sir1p functions by binding the origin recognition complex (ORC), which binds to HMR-E, and recruiting the other Sir proteins (Sir2p to -4p). ORCs also bind to hundreds of nonsilencer positions distributed throughout the genome, marking them as replication origins, the sites for replication initiation. HMR-E also acts as a replication origin, but compared to many origins in the genome, it fires extremely inefficiently and late during S phase. One postulate to explain this observation is that ORC's role in origin firing is incompatible with its role in binding Sir1p and/or the formation of silent chromatin. Here we examined a mutant HMR-E silencer and fusions between robust replication origins and HMR-E for HMR a silencing, origin firing, and replication timing. Origin firing within HMR a and from the HMR-E silencer itself could be significantly enhanced, and the timing of HMR a replication during an otherwise normal S phase advanced, without a substantial reduction in SIR1-dependent silencing. However, although the robust origin/silencer fusions silenced HMR a quite well, they were measurably less effective than a comparable silencer containing HMR-E's native ORC binding site.