Miracle-dz/UniFAR-FTUs huggingface dataset:
Impacts of dried whole eggs on productive performance, quality of fresh and stored eggs, reproductive organs and lipid metabolism of laying hens

1. Rejected eggs were processed by freezing, freezing and boiling, or autoclaving, dried at 55°C, and the chemical and amino-acid analysis and microbiological properties of the dried whole eggs (DWE) determined. The processed DWE was included in a laying-hen mash diet at 50 or 100 g/kg, mainly to replace soybean meal and maize, in a factorial design of 3 × 2 and fed to hens between 25 and 41 weeks of age. In addition, a control diet without DWE was used to create a total of 7 treatments; each having 5 replicates of 5 hens. 2. Hens fed the diet containing 50-g/kg frozen and boiled DWE and 100-g/kg frozen DWE laid the largest egg size, while hens fed the 50-g/kg frozen and boiled or autoclaved DWE diets yielded the highest egg mass and best feed conversion efficiency. 3. Hens fed the 50-g/kg frozen DWE laid eggs with a higher yolk indices, Haugh unit scores, and eggshell thickness and maintained higher Haugh unit scores during egg storage. 4. Yolk cholesterol significantly decreased in eggs from groups fed either the 50-g/kg frozen or autoclaved DWE diet, with freezing having the stronger effect. 6. In conclusion, 50-g/kg autoclaved DWE diets fed to laying hens between 25 and 41 weeks of age had no adverse effects on production, egg quality or reproductive organs, but decreased yolk cholesterol, and thus could be beneficially included in laying-hen diets.
Nipah Virus Infects Specific Subsets of Porcine Peripheral Blood Mononuclear Cells

Nipah virus (NiV), a zoonotic paramyxovirus, is highly contagious in swine, and can cause fatal infections in humans following transmission from the swine host. The main viral targets in both species are the respiratory and central nervous systems, with viremia implicated as a mode of dissemination of NiV throughout the host. The presented work focused on the role of peripheral blood mononuclear cells (PBMC) in the viremic spread of the virus in the swine host. B lymphocytes, CD4−CD8−, as well as CD4+CD8− T lymphocytes were not permissive to NiV, and expansion of the CD4+CD8− cells early post infection was consistent with functional humoral response to NiV infection observed in swine. In contrast, significant drop in the CD4+CD8− T cell frequency was observed in piglets which succumbed to the experimental infection, supporting the hypothesis that antibody development is the critical component of the protective immune response. Productive viral replication was detected in monocytes, CD6+CD8+ T lymphocytes and NK cells by recovery of infectious virus in the cell supernatants. Virus replication was supported by detection of the structural N and the non-structural C proteins or by detection of genomic RNA increase in the infected cells. Infection of T cells carrying CD6 marker, a strong ligand for the activated leukocyte cell adhesion molecule ALCAM (CD166) highly expressed on the microvascular endothelial cell of the blood-air and the blood-brain barrier may explain NiV preferential tropism for small blood vessels of the lung and brain.
Two-Stage Reconstruction With Autografts for Knee Dislocations

Traumatic knee dislocations are severe injuries that involve damage to the anterior cruciate ligament, the posterior cruciate ligament, and the lateral or medial ligamentous structures. There are no established methods of treatment. The objective of the current study was to report the clinical outcome of a two-stage autologous reconstruction on nine knees (eight patients). The mean followup was 40.1 months. The first stage of the reconstruction was done at a mean of 2 weeks after the injury, and the posterior cruciate ligament was reconstructed by an arthroscopically assisted technique using contralateral autogenous hamstring tendon as the graft material. Three months later, the second stage of the reconstruction was done for the ligaments that had not healed with conservative treatment. Arthroscopically assisted anterior cruciate ligament reconstruction was done on all of the knees using the ipsilateral autogenous hamstring tendon or bone-patellar tendon-bone as the graft material. At the same time, a medial collateral ligament reconstruction using an autogenous semitendinosus tendon was done on one knee, and reconstruction of the posterolateral ligamentous structures using a biceps tendon was done on three knees. Each of the knees that was reconstructed was capable of full extension, and the mean degree of passive flexion was 139.5° ± 5.2°. The mean side-to-side difference in anteroposterior total laxity (KT-1000 arthrometer, manual maximum) was 2.3 ± 1.9 mm. None of the knees had lateral or medial instability. All of the injured ligaments were able to be reconstructed with autografts, and severe contracture was able to be prevented. A good clinical outcome can be achieved when two-stage reconstruction is used for traumatic knee dislocations.
Pilot-Aided Carrier Recovery in the Presence of Phase Noise

The paper deals with carrier recovery based on pilot symbols in single-carrier systems. The system model considered in the paper includes the channel additive white noise and the phase noise that affects the local oscillators used for up/down-conversion. Wiener's method is used to determine the optimal filter in estimation of phase noise assuming that a sequence of equally spaced pilot symbols is available. Our analysis allows to capture the cyclostationary performance of the estimate, a phenomenon that is not considered in the previous literature. In the paper, closed-form formulas for the transfer function of the optimal filter and for the mean-square phase error are derived for the case where the phase noise is modelled as random phase walk. For this case, a suboptimal filter is proposed. Numerical results are presented to substantiate the analysis.
Cdk5/p35 Regulates Neurotransmitter Release through Phosphorylation and Downregulation of P/Q-Type Voltage-Dependent Calcium Channel Activity

Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase with close structural homology to the mitotic Cdks. The complex of Cdk5 and p35, the neuron-specific regulatory subunit of Cdk5, plays important roles in brain development, such as neuronal migration and neurite outgrowth. Moreover, Cdk5 is thought to be involved in the promotion of neurodegeneration in Alzheimer's disease. Cdk5 is abundant in mature neurons; however, its physiological functions in the adult brain are unknown. Here we show that Cdk5/p35 regulates neurotransmitter release in the presynaptic terminal. Both Cdk5 and p35 were abundant in the synaptosomes. Roscovitine, a specific inhibitor of Cdk5 in neurons, induced neurotransmitter release from the synaptosomes in response to membrane depolarization and enhanced the EPSP slopes in rat hippocampal slices. The electrophysiological study using each specific inhibitor of the voltage-dependent calcium channels (VDCCs) and calcium imaging revealed that roscovitine enhanced Ca2+ influx from the P/Q-type VDCC. Moreover, Cdk5/p25 phosphorylated the intracellular loop connecting domains II and III (LII-III) between amino acid residues 724 and 981 of isoforms cloned from rat brain of the α1A subunit of P/Q-type Ca2+ channels. The phosphorylation inhibited the interaction of LII-IIIwith SNAP-25 and synaptotagmin I, which were plasma membrane solubleN-ethylmaleimide-sensitive factor attachment protein (SNAP) receptor (SNARE) proteins and were required for efficient neurotransmitter release. These results strongly suggest that Cdk5/p35 inhibits neurotransmitter release through the phosphorylation of P/Q-type VDCC and downregulation of the channel activity.
Microfocusing at the PG1 beamline at FLASH

The Kirkpatrick–Baez (KB) refocusing mirrors unit at the PG1 beamline at FLASH has been newly designed, developed and fully commissioned. The vertical focal size of the KB optics is measured to be 5.8 ± 1 µm FWHM and the horizontal 6 ± 2 µm FWHM; astigmatism has been minimized to below 1 mm between waist positions. Such a tight focus is essential for the VUV double Raman spectrometer as it serves as an entrance slit for the first monochromator and defines its resolution to a very large extent. The Raman spectrometer is a permanent end-station at the PG1 beamline, dedicated to inelastic soft X-ray scattering experiments.
Association of structural brain imaging markers with alcoholism incorporating structural connectivity information: a regularized statistical approach

Brain imaging studies collect multiple imaging data types, but most analyses are done for each modality separately. Statistical methods that simultaneously utilize and combine multiple data types can instead provide a more holistic view of brain function. Here we model associations between alcohol abuse phenotypes and imaging data while incorporating prior scientific knowledge. Specifically, we utilize cortical thickness and integrated rectified mean curvature measures obtained by FreeSurfer software [1] to predict the alcoholism-related phenotypes while incorporating prior information from the structural connectivity between cortical regions. The sample consisted of 148 young (21-35 years) social-to-heavy drinking male subjects from several alcoholism risk studies [2,3,4]. Structural connectivity model [5] was used to estimate the density of connections between 66 cortical regions based on Desikan-Killiany atlas [6]. We employed a functional linear model with a penalty operator to quantify the relative contributions of imaging markers obtained from high resolution structural MRI (cortical thickness and curvature) as predictors of drinking frequency and risk-relevant personality traits, while co-varying for age. Model parameters were estimated by a unified approach directly incorporating structural connectivity information into the estimation by exploiting the joint eigenproperties of the predictors and the penalty operator [7]. We found that the best predictive imaging markers of the Alcohol Use Disorders Identification Test (AUDIT) score were the average thickness of left frontal pole (-), right transverse temporal gyrus (+), left inferior parietal lobule (+), right supramarginal gyrus (-), right rostral middle frontal gyrus (+), right precentral gyrus (+), left superior parietal lobule (-), left lateral orbitofrontal cortex (+), left rostral middle frontal gyrus (+), left postcentral gyrus (+) and left supramarginal gyrus (-), where (+) denotes positive and (-) negative association. In summary, the use of structural connectivity information allowed the incorporation of different modalities in associating cortical measures and alcoholism risk.
Customer-Supplier Issues in Software Development

Many studies list the customer-supplier -relationship related issues among the most important reasons for software project failures. Today most of the software development is done outside the organization actually using the software, so the organizational interface of customer and supplier is something that we just need to live with. Since it is not possible, or desirable, to eliminate this interface, we need proper ways to manage the issues introduced by this organizational interface. In this paper we shall look at the customer-supplier interface and issues related to it. The purpose of the paper is to demonstrate common issues and how they can manifest themselves in the software development context. Our study identified six issues related to customer-supplier interface. The issues were related to knowledge transfer, changes during projects, and power relations between customers and suppliers. The paper has implications both for the practice and research. For practitioners the identification and exploration of the issues will provide a solid basis to manage these problems as they come up in practice. For researchers the paper provides an empirically founded description of issues identified in customer-supplier interface.
Application of Value Engineering in Wireless Nano- sensor Network to Monitor Global warming Affected by Uncontrolled Urbanization

In the present scenario weather uncertainty is established as the greatest collective challenge faced by human beings. It is also well established that in weather science the most crucial variables are the least well predicted. Assessments of weather change impacts, which are useful for stakeholders and policymakers, depend critically on regional and decadal scale projections of weather extremes. Thus, weather scientists often need to develop qualitative inferences about inadequately predicted weather extremes based on insights from observations or conceptual understanding. These urgent societal priorities offer grounds for knowledge discovery approaches. The factors responsible for weather change in terms of environmental degradation and subsequently global warming leading subsequent change in agriculture, food production and food security. It also causes the uncertain storm and heavy rainfall which turns into flood. So, in this research work it is preferred to find out the relationship between climate degradation and global warming due environmental pollution and biological wastes through wireless nano sensors network (WNSN) caused by highly congested and uncontrolled development of urbanization to manage the habitant problem of huge population which is the major requirement of growth in developing countries like India.
Towards the Determination of Mytilus edulis Food Preferences Using the Dynamic Energy Budget (DEB) Theory

The blue mussel, Mytilus edulis, is a commercially important species, with production based on both fisheries and aquaculture. Dynamic Energy Budget (DEB) models have been extensively applied to study its energetics but such applications require a deep understanding of its nutrition, from filtration to assimilation. Being filter feeders, mussels show multiple responses to temporal fluctuations in their food and environment, raising questions that can be investigated by modeling. To provide a better insight into mussel–environment interactions, an experiment was conducted in one of the main French growing zones (Utah Beach, Normandy). Mussel growth was monitored monthly for 18 months, with a large number of environmental descriptors measured in parallel. Food proxies such as chlorophyll a, particulate organic carbon and phytoplankton were also sampled, in addition to non-nutritious particles. High-frequency physical data recording (e.g., water temperature, immersion duration) completed the habitat description. Measures revealed an increase in dry flesh mass during the first year, followed by a high mass loss, which could not be completely explained by the DEB model using raw external signals. We propose two methods that reconstruct food from shell length and dry flesh mass variations. The former depends on the inversion of the growth equation while the latter is based on iterative simulations. Assemblages of food proxies are then related to reconstructed food input, with a special focus on plankton species. A characteristic contribution is attributed to these sources to estimate nutritional values for mussels. M. edulis shows no preference between most plankton life history traits. Selection is based on the size of the ingested particles, which is modified by the volume and social behavior of plankton species. This finding reveals the importance of diet diversity and both passive and active selections, and confirms the need to adjust DEB models to different populations and sites.
Stability analysis of improved networked predictive control systems with random network delays

Considering the calculation difficulty of network controller which is resulted from the network delay, on the basis of G.P.L[1, 5], this paper gives a new method to calculate controller, there is a modification in the new method. Also this paper discusses stability of networked control systems (NCS) with random network delay in the forward and feedback channels using switched system theory. First, it is pointed out that the NCS with random delays can be represented by discrete-time switched system. Then, the necessary and sufficient conditions for the stability of closed-loop NCS with bounded random delays are derived based on LMIs.
On the Incorporation of Psychologically-Driven 'Music' Preference Models for Music Recommendation

Title of Thesis: ON THE INCORPORATION OF PSYCHOLOGICALLY-DRIVEN ‘MUSIC’ PREFERENCE MODELS FOR MUSIC RECOMMENDATION Monique Kathryn Dalton, Ethan J. Ferraro, Meg Galuardi, Michael L. Robinson, Abigail M. Stauffer, Mackenzie Thomas Walls Thesis Directed By: Professor Ramani Duraiswami, Department of Computer Science There are hundreds of millions of songs available to the public, necessitating the use of music recommendation systems to discover new music. Currently, such systems account for only the quantitative musical elements of songs, failing to consider aspects of human perception of music and alienating the listener’s individual preferences from recommendations. Our research investigated the relationships between perceptual elements of music, represented by the MUSIC model, with computational musical features generated through The Echo Nest, to determine how a psychological representation of music preference can be incorporated into recommendation systems to embody an individual’s music preferences. Our resultant model facilitates computation of MUSIC factors using The Echo Nest features, and can potentially be integrated into recommendation systems for improved performance. ON THE INCORPORATION OF PSYCHOLOGICALLY-DRIVEN ‘MUSIC’ PREFERENCE MODELS FOR MUSIC RECOMMENDATION
MULTI-OBJECTIVE MODELING FOR FAULT INDICATORS PLACEMENT USING OF NSGA II TO REDUCE OFF TIME AND COSTS IN DISTRIBUTION NETWORK

According to the reports of power companies, about 80-90% of the outages occurred in the network are due to the error in the distribution system. The occurrence of these outages leads to the customer dissatisfaction and the lack of energy sales and significant economic losses in the distribution companies. Thus increasing network reliability to reduce these losses has attracted the attention of many experts. In this paper, fault indicator placement is performed using multi-objective function. Creating high reliability and reducing costs are the main goals of this paper and for this purpose multi-goal objective function is used. Fault indicator placement caused a plan with respect to all conditions governing the issue. Optimization of this problem, especially for large networks is a complex and difficult task. In this paper, NSGA II algorithm is used for optimization.
In Vitro Assessment of Marine Bacillus for Use as Livestock Probiotics

Six antimicrobial-producing seaweed-derived Bacillus strains were evaluated in vitro as animal probiotics, in comparison to two Bacillus from an EU-authorized animal probiotic product. Antimicrobial activity was demonstrated on solid media against porcine Salmonella and E. coli. The marine isolates were most active against the latter, had better activity than the commercial probiotics and Bacillus pumilus WIT 588 also reduced E. coli counts in broth. All of the marine Bacillus tolerated physiological concentrations of bile, with some as tolerant as one of the probiotics. Spore counts for all isolates remained almost constant during incubation in simulated gastric and ileum juices. All of the marine Bacillus grew anaerobically and the spores of all except one isolate germinated under anaerobic conditions. All were sensitive to a panel of antibiotics and none harbored Bacillus enterotoxin genes but all, except B. pumilus WIT 588, showed some degree of β-hemolysis. However, trypan blue dye exclusion and xCELLigence assays demonstrated a lack of toxicity in comparison to two pathogens; in fact, the commercial probiotics appeared more cytotoxic than the majority of the marine Bacillus. Overall, some of the marine-derived Bacillus, in particular B. pumilus WIT 588, demonstrate potential for use as livestock probiotics.
On classification and realization of Poisson-Lie anomalies

We introduce the concept of (nonlinear) Poisson-Lie cohomology of Lie algebras and show that it classifies possible anomalies of PoissonLie symmetries. Given a Poisson-Lie 2-cocycle, we also explicitely construct a symplectic manifold which realizes the corresponding anomaly. We call this symplectic manifold an anomalous Heisenberg double since it can be viewed as a generalisation of the Heisenberg double of Semenov-Tian-Shansky. We show that particular classes of Poisson-Lie anomalies naturally arise by taking a limit q → ∞ of known Poisson-Lie symmetric dynamical systems. In particular, we establish that the q → ∞ limit of the quasitriangular q-WZW model is underlied by a particular anomalous Heisenberg double of the loop group and we evaluate the corresponding anomalous q → ∞ current algebra brackets. We also show that the q →∞WZW model admits a chiral decomposition compatible with the Poisson-Lie symmetry and the chiral theory can be dualized in a remarkable way. Finally, we evaluate the exchange (braiding) relations for the q →∞ chiral WZW fields in both the original and the dual pictures.
Cytokine and chemokine responses in the acute phase of hepatitis B virus replication in naive and previously vaccinated blood and plasma donors.

BACKGROUND Blood and plasma donor screening for hepatitis B virus (HBV) DNA, HBV surface antigen (HBsAg), and antibodies to surface (anti-HBs) and core (anti-HBc) antigens allows identification of individuals who acquired HBV despite previous HBV vaccination. METHODS Of 14 HBV acute infection donor panels (HBV-DNA-positive/anti-HBc-negative), 6 donors were previously vaccinated (anti-HBs+). We investigated the differences in viral kinetics and immune responses in vaccinated and nonvaccinated individuals. Serial specimens were characterized for HBV DNA and serological markers and 39 cytokines. RESULTS The rate of viral load increase was blunted, and virus was cleared more rapidly in vaccinated individuals (P = .004). In unvaccinated individuals, induced protein 10 (IP-10), interleukin 10 (IL-10), macrophage inflammatory protein 1β (MIP-1β), and soluble interleukin 2Rα (sIL-2Rα) levels were commonly elevated at the time of peak viremia. In contrast, vaccinated individuals had earlier peaks in IL-10 and IP-10 responses that occurred at much lower viral loads and coincided with anamnestic anti-hepatitis B surface (HBs) responses and clearance of viremia. CONCLUSION There is earlier engagement of innate and adaptive immunity in infected subjects with previous vaccination, possibly explaining suppressed viremia in vaccine breakthrough infections. Although breakthrough infections occur in partially protected vaccine recipients, vaccination likely contributes to early control of replication, limiting immune activation and preventing development of clinically significant acute and chronic HBV infection.