Miracle-dz/UniFAR-FTUs huggingface dataset:
Using D2RQ and Ontop to publish relational database as Linked Data

Having dataset in relational database published and accessed on the Web of Data is a hot issue. In this paper, we present implementation of publishing relational database as Linked Data with two open-source platforms, particularly D2RQ and Ontop. Both platforms provide their own way to translate databases into RDF Graphs. However, in case of querying data, Ontop shows much better performance than D2RQ.
Data Monitoring " A Hypothesis-Testing Approach for Treatment-Outcome Research

Traditional inferential statistics require that hypotheses be evaluated at only 1 sample size. That is, researchers must choose how many participants will be included in a study before conducting analyses; they are not allowed to add data if initial results are not significant. This requirement forces researchers to choose among including more participants than necessary, risking inconclusive results, or violating the requirement by adding participants. This study presents a more flexible approach, called data monitoring, that allows repeating an analysis as the sample increases. First, the cost of the uncorrected data monitoring that researchers sometimes do is estimated. Second, the correction that is needed to allow data monitoring while holding an overall alpha at a desired level is estimated. Third, the power of data monitoring is compared with traditional approaches. This study also provides an example of the use of data monitoring. At least in some circumstances, data monitoring can reduce Type II error or the number of participants needed without sacrificing Type I error.
Salient video stills: content and context preserved

A new class of images called salient stills is demonstrated and a software development platform for their creation is discussed. These images do not represent one discrete moment of time, as do a photograph or single video frame. Rather, one image reflects the aggregate of the temporal changes that occur in a moving image sequence with the salient features preserved. By the application of an affine transformation and non-linear temporal processing, multiple frames of an image sequence, which may include variations in focal-length or field-of-view, are combined to create a single still image. The still image may have multi-resolution patches, a larger field-of-view, or higher overall resolution than any individual frame in the original image sequence. It may also contain selected salient objects from any one of the sequence of video frames. The still can be created automatically or with user intervention. A by-product of the salient still process is a structured representation of moving image data.
Vaccination with autologous tumor-derived heat-shock protein gp96 after liver resection for metastatic colorectal cancer.

PURPOSE Heat shock proteins (HSP) from tumor cells contain the gp96 polypeptide associated with cancer-specific antigenic peptides. Mice that are immunized with HSP/peptide-complex (HSPPC) derived from cancer tissue reject tumor from which HSPs are purified. We tested in humans whether vaccination with HSPPC-gp96 (Oncophage) from autologous liver metastases of colorectal carcinoma induces cancer-specific T-cell responses in patients rendered disease free by surgery. EXPERIMENTAL DESIGN Twenty-nine consecutive patients underwent radical resection of liver metastases [Memorial Sloan-Kettering Cancer Center (MSKCC) score 1-3 (good prognosis), 18 patients; score 4-5 (bad prognosis), 11 patients] and received autologous tumor-derived HSPPC-96. Two vaccine cycles were administered (four weekly injections followed by four biweekly injections after 8 weeks). Class-I HLA-restricted, anti-colon cancer lines T-cell response was measured by ELISPOT assay on peripheral blood mononuclear cells (PBMCs) obtained before and after vaccination. Feasibility, safety, and possible clinical benefits were also evaluated. RESULTS Either a de novo induced or a significant increase of preexisting class I HLA-restricted T-cell-mediated anti-colon cancer response was observed in 15 (52%) of 29 patients. Frequency of CD3+, CD45RA+, and CCR7- T lymphocytes increased in immune responders. No relevant toxicity was observed. As expected, patients with good prognosis had a significantly better clinical outcome than those with poor prognosis [2-year overall survival (OS), 89 versus 64%, P = 0.001; disease-free survival (DFS), 46 versus 18%, P = 0.001]. Patients with immune response had a statistically significant clinical advantage over nonresponding subjects (2-year OS, 100% versus 50%, P = 0.001; DFS, 51% versus 8%, P = 0.0001). Occurrence of immune response led to better tumor-free survival, whatever the predicted prognosis was (hazard ratio, 0.11-0.12 with/without stratification; P = 0.0012-0.0003). CONCLUSIONS HSPPC-96 vaccination after resection of colorectal liver metastases is safe and elicits a significant increase in CD8+ T-cell response against colon cancer. In this limited number of patients, two-year OS and DFS were significantly improved in subjects with postvaccination antitumor immune response, independently from other clinical prognostic factors.
The Walden’s Paths Quiz Engine

The Walden’s Paths project is developing tools to facilitate the inclusion of Web-based materials in classroom education. It currently includes components to create, present and manage paths that recontextualize information on the Web. In this paper we present the Quiz Engine, a fullfeatured online testing system that extends the repertoire of our tools to include Web-based assessment of the knowledge gained by the students. It allows teachers to author the different types of questions commonly used in paper-based testing and generates interactive as well as passive tests with various characteristics. It is designed to support teachers with little experience in Web technologies to create and administer online tests in a variety of settings for aiding students’ selfassessment while learning or for administering graded examinations.
A study on the compatibility between one-bottle dentin adhesives and composite resins using micro-shear bond strength

Objectives This study was performed to determine whether the combined use of one-bottle self-etch adhesives and composite resins from same manufacturers have better bond strengths than combinations of adhesive and resins from different manufacturers. Materials and Methods 25 experimental micro-shear bond test groups were made from combinations of five dentin adhesives and five composite resins with extracted human molars stored in saline for 24 hr. Testing was performed using the wire-loop method and a universal testing machine. Bond strength data was statistically analyzed using two way analysis of variance (ANOVA) and Tukey's post hoc test. Results Two way ANOVA revealed significant differences for the factors of dentin adhesives and composite resins, and significant interaction effect (p < 0.001). All combinations with Xeno V (Dentsply De Trey) and Clearfil S3 Bond (Kuraray Dental) adhesives showed no significant differences in micro-shear bond strength, but other adhesives showed significant differences depending on the composite resin (p < 0.05). Contrary to the other adhesives, Xeno V and BondForce (Tokuyama Dental) had higher bond strengths with the same manufacturer's composite resin than other manufacturer's composite resin. Conclusions Not all combinations of adhesive and composite resin by same manufacturers failed to show significantly higher bond strengths than mixed manufacturer combinations.
Nonparametric modelling of VO2 response to exercise

This paper investigates the modelling of oxygen consumption (VO2) response to jogging exercise on treadmill. Unlike most of the previous methods, which often use simple parametric models, e.g., first order linear time invariant model, this study applied a nonparametric kernel based regularised method to estimate VO2 to address the ill-conditioned modelling problem and achieve accurate estimation. In particular, it is worthy to be noted that the selection of kernels will affect the results for different modelling scenarios. Therefore, in this research, both radial basis kernel and stable spline kernel were selected for testing. In order to select the favourable kernel for this system, a simulation related to VO2-jogging speed was carried out. The results of simulation indicated that spline kernel can achieve higher accuracy comparing to radial basis function kernel. Experimentally, the kernel based estimation method and spline kernel were tested using six participants. From the results, an average impulse response is obtained. It showed the VO2 estimation, based on the average finite impulse response, is fitted well to the six observations collected from the participants.
Cross-Cultural Variability in Self-Continuity Warranting Strategies

Previous research has shown that (a) when individuals are pressed to justify their persistence through time (i.e., their self-continuity), they do so by constructing autobiographical life stories or by recognizing temporally stable personal attributes and (b) the prevalence in the endorsement of these strategies varies across cultural groups. Here we prompted for both life stories and temporally stable personal attributes among immigrant Asian Canadians and nonimmigrant Euro-Canadians. Life stories were coded for autobiographical reasoning processes and the frequency of stable personal attributes was noted. Immigrant Asian Canadians exhibited a heightened complexity of autobiographical reasoning, whereas nonimmigrant Euro-Canadians proffered more temporally stable attributes. These results inform understanding regarding self-continuity warranting strategies; the ways in which individuals use language to justify their sense of self through time vary culturally.
A numerical study of a heart phantom model

In this paper, we develop a computational heart phantom model based on magnetic resonance imaging (MRI) of a dynamic multi-modality heart phantom. The phantom is made of a hydrogel material which mimics the elasticity of human soft tissue, and is composed of anatomically correct left and right ventricle structures. The numerical analysis is carried out using the neo-Hookean constitutive model, and the C++ based object-oriented finite element library libMesh is used to solve the fully nonlinear governing equations. We derive the partial differential equations into a set of Lagrangian mesh, and use the weighted residual Galerkin method and Newton iteration solver in the numerical scheme. To validate the numerical model, the displacements and strains of some representative points are compared with experimental measurements and MRI-based strain estimations. Good agreement is obtained, and limitations of the model are discussed.
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iagn&sis )sing a *irst-. r/er 1t&c3astic 4ang5age 63at 4earns 73a8an 73a9ra:arti; <&s3an <a==&3an; an/ >e&rge *. 45ger Department of Computer Science University of New Mexico Albuquerque, NM 87131 {cc, roshan, luger} @cs.unm. edu
Development of Fabrication Methods of Filler/Polymer Nanocomposites: With Focus on Simple Melt-Compounding-Based Approach without Surface Modification of Nanofillers

Many attempts have been made to fabricate various types of inorganic nanoparticle-filled polymers (filler/polymer nanocomposites) by a mechanical or chemical approach. However, these approaches require modification of the nanofiller surfaces and/or complicated polymerization reactions, making them unsuitable for industrial-scale production of the nanocomposites. The author and coworkers have proposed a simple melt-compounding method for the fabrication of silica/polymer nanocomposites, wherein silica nanoparticles without surface modification were dispersed through the breakdown of loose agglomerates of colloidal nano-silica spheres in a kneaded polymer melt. This review aims to discuss experimental techniques of the proposed method and its advantages over other developed methods.
Serotype Distribution and Antimicrobial Resistance of Streptococcus pneumoniae Isolates Causing Invasive and Noninvasive Pneumococcal Diseases in Korea from 2008 to 2014

Introduction. Streptococcus pneumoniae is an important pathogen with high morbidity and mortality rates. The aim of this study was to evaluate the distribution of common serotypes and antimicrobial susceptibility of S. pneumoniae in Korea. Methods. A total of 378 pneumococcal isolates were collected from 2008 through 2014. We analyzed the serotype and antimicrobial susceptibility for both invasive and noninvasive isolates. Results. Over the 7 years, 3 (13.5%), 35 (10.8%), 19A (9.0%), 19F (6.6%), 6A (6.1%), and 34 (5.6%) were common serotypes/serogroups. The vaccine coverage rates of PCV7, PCV10, PCV13, and PPSV23 were 21.4%, 23.3%, 51.9%, and 62.4% in all periods. The proportions of serotypes 19A and 19F decreased and nonvaccine serotypes increased between 2008 and 2010 and 2011 and 2014. Of 378 S. pneumoniae isolates, 131 (34.7%) were multidrug resistant (MDR) and serotypes 19A and 19F were predominant. The resistance rate to levofloxacin was significantly increased (7.2%). Conclusion. We found changes of pneumococcal serotype and antimicrobial susceptibility during the 7 years after introduction of the first pneumococcal vaccine. It is important to continuously monitor pneumococcal serotypes and their susceptibilities.
Scrambling and Descrambling SMT-LIB Benchmarks

Each year, the benchmarks for the SMT Competition are drawn from a known pool of benchmarks, the SMT Library. Competing solvers, rather than determine benchmark satisfiability from scratch, could thus cheat by simply looking up the correct answer for each benchmark in the library. To make this form of cheating more difficult, benchmarks in the SMT Competition are scrambled. We demonstrate that the current scrambling algorithm, which has been in use since 2011, is ineffective at obscuring the original benchmark. We propose an improved scrambling algorithm, and show that the problem of identifying the original benchmark under this improved algorithm is GI-complete.
Interactive Visual Synthesis of Analytic Knowledge

A visual investigation involves both the examination of existing information and the synthesis of new analytic knowledge. This is a progressive process in which newly synthesized knowledge becomes the foundation for future discovery. In this paper, we present a novel system supporting interactive, progressive synthesis of analytic knowledge. Here we use the term "analytic knowledge" to refer to concepts that a user derives from existing data along with the evidence supporting such concepts. Unlike existing visual analytic-tools, which typically support only exploration of existing information, our system offers two unique features. First, we support user-system cooperative visual synthesis of analytic knowledge from existing data. Specifically, users can visually define new concepts by annotating existing information, and refine partially formed concepts by linking additional evidence or manipulating related concepts. In response to user actions, our system can automatically manage the evolving corpus of synthesized knowledge and its corresponding evidence. Second, we support progressive visual analysis of synthesized knowledge. This feature allows analysts to visually explore both existing knowledge and synthesized knowledge, dynamically incorporating earlier analytic conclusions into the ensuing discovery process. We have applied our system to two complex but very different analytic applications. Our preliminary evaluation shows the promise of our work
Distinguishing Sarcasm From Literal Language: Evidence From Books and Blogging

Sarcasm production and comprehension have been traditionally described in terms of pragmatic factors. Lexical cues have received less attention, but they may be important potential indicators. A major obstacle to examining such features is determining sarcastic intent. One solution is to analyze statements explicitly marked as being sarcastic. This study examined Twitter postings marked with #sarcasm as well as dialog from Google Books containing the phrase “said sarcastically. ” We used word counting and part-of-speech tagging to compare specific lexical features of the explicitly-marked sarcastic statements to statements by the same author not marked as sarcastic. Our results broadly support the Lexical Cues Hypothesis—certain word-level cues, such as interjections and positive affect terms, are stereotypic of sarcasm. A model incorporating these features performed comparably to human raters in making sarcastic versus nonsarcastic judgments. This finding shows promise for future work toward automatically identifying sarcasm in text.
Shared Visual Attention and Memory Systems in the Drosophila Brain

Background Selective attention and memory seem to be related in human experience. This appears to be the case as well in simple model organisms such as the fly Drosophila melanogaster. Mutations affecting olfactory and visual memory formation in Drosophila, such as in dunce and rutabaga, also affect short-term visual processes relevant to selective attention. In particular, increased optomotor responsiveness appears to be predictive of visual attention defects in these mutants. Methodology/Principal Findings To further explore the possible overlap between memory and visual attention systems in the fly brain, we screened a panel of 36 olfactory long term memory (LTM) mutants for visual attention-like defects using an optomotor maze paradigm. Three of these mutants yielded high dunce-like optomotor responsiveness. We characterized these three strains by examining their visual distraction in the maze, their visual learning capabilities, and their brain activity responses to visual novelty. We found that one of these mutants, D0067, was almost completely identical to dunce1 for all measures, while another, D0264, was more like wild type. Exploiting the fact that the LTM mutants are also Gal4 enhancer traps, we explored the sufficiency for the cells subserved by these elements to rescue dunce attention defects and found overlap at the level of the mushroom bodies. Finally, we demonstrate that control of synaptic function in these Gal4 expressing cells specifically modulates a 20–30 Hz local field potential associated with attention-like effects in the fly brain. Conclusions/Significance Our study uncovers genetic and neuroanatomical systems in the fly brain affecting both visual attention and odor memory phenotypes. A common component to these systems appears to be the mushroom bodies, brain structures which have been traditionally associated with odor learning but which we propose might be also involved in generating oscillatory brain activity required for attention-like processes in the fly brain.
Denture Adhesives – A Review

: Denture adhesives are used to improve the retention and stability of dentures in a large number of patients without any advice from dentists. In the United States, denture adhesives are used by more than 5 million denture wearers. Denture wearers mainly use denture adhesive to compensate for ill fitting dentures as well as to alleviate discomfort. It seems reasonable for denture wearers to use denture adhesives to enhance denture retention and stability. However, dental professionals are still undecided as to whether dentists should advise denture wearers to use them. Hence the aim of this review is to throw light on the literature evidence of effectiveness of denture adhesive by complete denture wearers
Relations among different privacy notions

We present a comprehensive view of the relations among several privacy notions: differential privacy (DP) [1], Bayesian differential privacy (BDP) [2], semantic privacy (SP) [3], and membership privacy (MP) [4]. The results are organized into two parts. In part one, we extend the notion of semantic privacy (SP) to Bayesian semantic privacy (BSP) and show its essential equivalence with Bayesian differential privacy (BDP) in the quantitative sense. We prove the relations between BDP, BSP, and SP as follows: ∊-BDP ⇐ (1/2 − 1/e<sup>∊</sup> + 1)-BSP, and ∊-BDP ⇒ (e<sup>∊</sup> − 1)-BSP ⇒ (e<sup>∊</sup> − 1)-SP. In addition, we obtain a minor result ∊-DP ⇐ (1/2 − 1/e<sup>∊</sup> + 1)-SP, which improves the result of Kasiviswanathan and Smith [3] stating ∊-DP ⇐ ∊/6-SP for ∊ ≤ 1.35. In part two, we establish the relations between BDP and MP. First, ∊-BDP ⇒ ∊-MP. Second, for a family of distributions that are downward scalable in the sense of Li et al. [4], it is shown that ∊-BDP ⇐ ∊-MP.
N-(2-Hydroxybenzyl)adamantan-1-aminium 4-methylbenzenesulfonate

In the crystal structure of the title salt, C17H24NO+·C7H7O3S−, the N-(2-hydroxybenzyl)adamantan-1-aminium cations and 4-methylbenzenesulfonate anions are linked by O—H⋯O and N—H⋯O hydrogen bonds. C—H⋯π interactions are also observed between the cation and the anion.
Imaging Mass Spectrometry Visualizes Ceramides and the Pathogenesis of Dorfman-Chanarin Syndrome Due to Ceramide Metabolic Abnormality in the Skin

Imaging mass spectrometry (IMS) is a useful cutting edge technology used to investigate the distribution of biomolecules such as drugs and metabolites, as well as to identify molecular species in tissues and cells without labeling. To protect against excess water loss that is essential for survival in a terrestrial environment, mammalian skin possesses a competent permeability barrier in the stratum corneum (SC), the outermost layer of the epidermis. The key lipids constituting this barrier in the SC are the ceramides (Cers) comprising of a heterogeneous molecular species. Alterations in Cer composition have been reported in several skin diseases that display abnormalities in the epidermal permeability barrier function. Not only the amounts of different Cers, but also their localizations are critical for the barrier function. We have employed our new imaging system, capable of high-lateral-resolution IMS with an atmospheric-pressure ionization source, to directly visualize the distribution of Cers. Moreover, we show an ichthyotic disease pathogenesis due to abnormal Cer metabolism in Dorfman–Chanarin syndrome, a neutral lipid storage disorder with ichthyosis in human skin, demonstrating that IMS is a novel diagnostic approach for assessing lipid abnormalities in clinical setting, as well as for investigating physiological roles of lipids in cells/tissues.
AUTORADIOGRAPHIC AND CYTOCHEMICAL EVIDENCE FOR SYNTHESIS OF A LYSINE-CONTAINING RIBONUCLEOPROTEIN IN NUCLEOLI INHIBITED BY ACTINOMYCIN D

Biochemical evidence for protein synthesis on nuclear ribosomes has accumulated in several laboratories in recent years (1, 2, 5). The morphologic sites of this activity in the intact mammal ian cell, in particular the respective roles of the nucleolus and chromosomes in nucleoprotein and nucleic acid synthesis, remain unclear (6-12). A quantitative autoradiographic and cytochemical study of this question has been reattempted by comparing the relative uptake of H 3lysine and H3-uridine or HS-cytidine in untreated HeLa cells with that in cells in which nucleolar R N A synthesis was selectively inhibited by low concentrations of Actinomycin D according to the method of Perry (13). In parallel, some cellular sites of e-amino groups were stained with Biebrich scarlet (14, 15). It was found that lysine is rapidly incorporated into a nucleolar material solubilized either by agents which hydrolyze R N A or by the proteolytic enzyme trypsin. This incorporation is inhibited by concentrations of Actinomycin D which also selectively inhibit the synthesis of nucleolar R N A ; but lysine incorporation is not inhibited in extranucleolar chromatin and cytoplasm. When stained for basic protein with Biebrich scarlet under selective conditions of fixation, nucleoli Showing lysine incorporation present a characteristic granular substructure not exhibited, or severely altered, in actinomycin-treated cells (16) and in cells treated under conditions of R N A extraction. M A T E R I A L S A N D M E T H O D S