Miracle-dz/UniFAR-FTUs huggingface dataset:
Improving the Care of Dual Eligible Patients in Rural Federally Qualified Health Centers

Background: Dual eligible persons are those covered by both Medicare and Medicaid. There were 9.6 million dual eligible persons in the United States and 82 000 in West Virginia in 2010. Dual eligibles are poorer, sicker, and more burdened with serious mental health conditions than Medicare or Medicaid patients as a whole. Their health care costs are significantly higher and they are more likely to receive fragmented ineffective care. Purpose: To improve the care experience and health care outcomes of dual eligible patients by the expanded use of care coordinators and clinical pharmacists. Methods: During 2012, 3 rural federally qualified community health centers in West Virginia identified 200 dual eligible patients each. Those with hospitalizations received more frequent care coordinator contacts. Those on more than 15 chronic medications had drug utilization reviews with recommendations to primary care providers. Baseline measures included demographics, chronic diseases, total medications and Beers list medications, hospitalization, and emergency room (ER) use in the previous year. Postintervention measures included hospitalization, ER use, total medications, and Beers list medications. Results: Out of 556 identified patients, 502 were contacted and enrolled. Sixty-five percent were female. The median age was 69 years, with a range of 29 to 93 years. Nineteen percent (19%) of patients were on 15 or more medications, 56% on psychotropic medication, and 33% on chronic opiates. One site showed reductions of 34% in hospitalizations and 25% in ER visits during the intervention year. For all sites combined, there was a 5.5% reduction in total medications and a 14.8% reduction in Beers list medications. Conclusions: A modest investment in care coordination and clinical pharmacy review can produce significant reductions in hospitalization and harmful polypharmacy for community dwelling dual eligible patients.
Characterization of astrocyte‐specific conditional knockouts

Conditional gene knockouts are a very powerful tool for elucidating gene function in animal physiology and behavior. To obtain cell‐specific knockouts, a promoter is utilized that drives expression of Cre recombinase specifically to the cell population of interest. We describe several transgenic lines of mice that were created in an attempt to obtain astrocyte‐specific gene recombination. A 2 kb fragment from the human glial fibrillary acidic protein promoter is utilized to drive expression of inducible Cre recombinase, with both the Tet‐Off and tamoxifen responsive systems. We show data obtained from crosses with two Cre reporter lines, ROSA26R and an astrocyte Cre reporter created in our laboratory, to assess the cell specificity of gene recombination. Additionally, our system is shown to successfully recombine a floxed Connexin43 locus, although recombination is not as extensive as seen in crosses with reporter lines. genesis 45:292–299, 2007. © 2007 Wiley‐Liss, Inc.
A randomized controlled trial of a home-visiting intervention on cognition and behavior in term low birth weight infants.

OBJECTIVES To determine whether early psychosocial intervention with low birth weight term (LBW-T) infants improved cognition and behavior and to compare LBW-T with normal birth weight (NBW) infants. STUDY DESIGN A randomized controlled trial was carried out in Kingston, Jamaica, with 140 LBW-T infants (weight<2500 g). The intervention comprised weekly home visits by paraprofessionals for the first 8 weeks of life aimed at improving maternal-child interaction. LBW-T and 94 matched NBW (weight 2500 to 4000 g) infants were recruited from the main maternity hospital. Main outcome measures were problem solving (2 means-end tests: cover and support) and 4 behavior ratings at 7 months. Analyses used were the t test for intervention effects and multiple regression to compare LBW and NBW infants. RESULTS LBW-T intervened infants had higher scores than LBW-T control infants on the cover test (P<.05) and were more cooperative (P<.01) and happy (P<.05). LBW-T control infants had poorer scores on both the cover (P<.001) and support tests (P<.01), vocalized less (P<.02), and were less cooperative (P<.001), happy (P<.02), and active (P<.02) than NBW infants. LBW-T intervened infants had lower scores than NBW infants only on the support test (P<.05). CONCLUSIONS Early low-cost intervention can improve cognition and behavior of LBW-T infants in developing countries.
Anaerobic ortho Dechlorination of Polychlorinated Biphenyls by Estuarine Sediments from Baltimore Harbor

Reductive dechlorination of the ortho moiety of polychlorinated biphenyls (PCBs) as well as of meta and para moieties is shown to occur in anaerobic enrichments of Baltimore Harbor sediments. These estuarine sediments ortho dechlorinated 2,3,5,6-chlorinated biphenyl (CB), 2,3,5-CB, and 2,3,6-CB in freshwater or estuarine media within a relatively short period of 25 to 44 days. ortho dechlorination developed within 77 days in marine medium. High levels of ortho dechlorination (>90%) occurred when harbor sediments were supplied with only 2,3,5-CB. Incubation with 2,3,4,5,6-CB or 2,3,4,5-CB resulted in the formation of the ortho dechlorination product 3,5-CB; however, para dechlorination of these congeners always preceded ortho chlorine removal. ortho dechlorination of PCBs is an exceedingly rare event that has not been reported previously for marine or estuarine conditions. The activity was reproducible and could be sustained through sequential transfers. In contrast, freshwater sediments incubated under the same conditions exhibited only meta and para dechlorinations. The results indicate that unique anaerobic dechlorinating activity is catalyzed by microorganisms in the estuarine sediments from Baltimore Harbor.
Item Recommendation in Collaborative Tagging Systems

Along with the new opportunities introduced by Web 2.0 and collaborative tagging systems, several challenges have to be addressed too, notably, the problem of information overload. Recommender systems are among the most successful approaches for increasing the level of relevant content over the “noise. ” Traditional recommender systems fail to address the requirements presented in collaborative tagging systems. This paper considers the problem of item recommendation in collaborative tagging systems. It is proposed to model data from collaborative tagging systems with three-mode tensors, in order to capture the three-way correlations between users, tags, and items. By applying multiway analysis, latent correlations are revealed, which help to improve the quality of recommendations. Moreover, a hybrid scheme is proposed that additionally considers content-based information that is extracted from items. Experimental comparison, using data from a real collaborative tagging system (Last.fm), against both recent tag-aware and traditional (non tag aware) item recommendation algorithms indicates significant improvements in recommendation quality. Moreover, the experimental results illustrate the advantage of the proposed hybrid scheme.
Cognitive and psychological functioning in focal dermal hypoplasia

Focal dermal hypoplasia (FDH) is a condition caused by heterozygous mutation of the PORCN gene on chromosome Xp22.3. It impacts the primitive ectoderm and mesoderm, affecting skin, teeth, nails, hair, musculoskeletal development, and vision and hearing. To date, there has been no systematic research examining the psychoeducational impact of the disorder. The current study examined emotional, behavioral, adaptive, and intellectual ability in 17 subjects with ages ranging from 3 to 55 with FDH attending the 2013 Annual Family Conference of the National Foundation for Ectodermal Dysplasias. Findings suggested overall average functioning in all areas. However, wide variability was noted in this sample, with 3 participants (18%) exhibiting overall cognitive ability in the borderline to impaired range. These findings are consistent with previous reports suggesting intellectual impairment in 15% of persons with FDH. Similarly, a subgroup of children was rated by parents as exhibiting difficulties with behavior (2 out of 11; 18%) and emotions (5 out of 11; 45%). Of particular concern was withdrawn behavior, reported by 65% of parents. These findings suggest that clinicians should routinely screen persons with FDH to rule out cognitive and emotional/behavioral difficulties and offer timely treatment. Future research should focus on identifying risk factors for psychoeducational problems in this population. © 2016 Wiley Periodicals, Inc.
Emotional Numbing in Posttraumatic Stress Disorder: Current and Future Research Directions

Objective: Despite being understudied and poorly understood relative to the chronic fear, anxiety and other aversive emotional states that occur in the immediate aftermath of trauma, emotional numbing has become a core defining feature of posttraumatic stress disorder (PTSD). Method: This paper seeks to briefly review the literature bearing on these seemingly disparate emotional responses to trauma as well as theoretical accounts of emotional numbing that have been proffered to date. We then offer an alternative theory of posttraumatic emotional functioning and review empirical support for this model. Result: The experience of trauma produces very intense emotions such as overwhelming fear, horror, and anxiety, and these reactions can linger for a lifetime. Many trauma survivors also report restrictions in their emotional experience – a phenomenon most commonly referred to as emotional numbing. In contrast to previous accounts of posttraumatic emotional functioning our model posits that individuals with PTSD have difficulty expressing positive emotions as a result of re-experiencing states. We further argue that patients with PTSD are capable of experiencing and expressing the full range of emotions that were available pretraumatically. Conclusion: Our model holds that individuals with PTSD are not, in fact, ‘emotionally numb’ as a result of traumatic experience. Rather, PTSD is associated with hyperresponsivity to negatively valenced emotional stimuli. Consequently, patients with PTSD require more intense positive stimulation to access the full complement of appetitive or pleasant emotional behaviour.
Real-Time Vision-Based Driver Drowsiness/Fatigue Detection System

In this paper, a vision system for monitoring driver's vigilance is presented. The level of vigilance is determined by integrating a number of facial parameters. In order to estimate these parameters, the facial features of eyes, mouth and head are first located in the input video sequence. The located facial features are then tracked over the subsequent images. Facial parameters are estimated during facial feature tracking. The estimated parametric values are collected and analyzed every fixed time interval to provide a real-time vigilance level of the driver. A series of experiments on real sequences were demonstrated to reveal the feasibility of the proposed system.
Requirement for cell replication in the fixation and expression of the transformed state in mouse cells treated with 4‐nitroquinoline‐1‐oxide

A31‐714 cells, a subclone derived from BALB/3T3, did not produce transformed foci when kept under culture conditions of density‐dependent inhibition after treatment with 4NQO in either the growing or the non‐growing state. The transformation frequency increased to nearly maximum level only when the cells had undergone more than four cell generations after 4NQO‐treatment. Cells which were first kept in a non‐growing state after 4NQO‐treatment, rapidly lost the ability to exhibit transformation even when they were subsequently returned to a growing state. On the other hand, the cells which were allowed one cell replication soon after 4NQO‐treatment retained their ability to produce transformed foci even after being kept in the non‐growing state for as long as 6 days thereafter. These results suggest that one cell generation is required for the fixation of transformation, and more than four cell generations are required for the expression of the transformed state.
Impact of Rape on Female Sexuality: Review of Selected Literature

This article reviews the medical and psychologic literature on the impact of rape on female sexuality. Studies documented moderately high rates of genital injuries and moderate rates of sexually transmitted infections postrape and significantly greater difficulties with aspects of reproductive/sexual functioning, including dyspareunia, endometriosis, menstrual irregularities, and chronic pelvic pain for raped compared with nonraped women. Raped women also engaged in significantly more high-risk sexual behaviors. Posttraumatic stress disorder emerged as an important mediator of sexual victimization and sexual health. An integrative model outlining interrelated physical, psychologic, biologic, and behavioral factors postrape was presented to assimilate review findings.
Cardiovascular risk and insulin resistance in patients with obstructive sleep apnea.

BACKGROUND Obstructive sleep apnea (OSA) has been linked to cardiovascular and cerebrovascular diseases in previous studies. However, it remains unclear whether OSA relates to cardiovascular outcomes independently of obesity and/or insulin resistance. MATERIAL/METHODS At a tertiary referral teaching hospital, this cross-sectional analysis of 98 subjects (28 without, 39 with mild-moderate, and 31 with severe OSA) aimed to determine whether OSA relates to National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) cardiovascular risk independently of obesity and insulin resistance. OSA was diagnosed by attended polysomnography. The insulin resistance index (HOMA-IR) was based on a homeostasis model assessment method. RESULTS Of the patients without to those with mild-moderate to those with severe OSA, significant increases were observed in NCEP ATP III risk [median (25%, 75% quartiles) from 2.0 (1.0, 8.0) to 3.0 (1.0, 12.0) to 16.0 (5.3, 20.0)%, p <0.001 for the trend] in association with increases in HOMA-IR (p<0.001), diastolic (p=0.039) and mean blood pressure (p=0.016), serum triglycerides (p=0.047), apolipoprotein B (p=0.039), plasma fibrinogen (p=0.013), and fasting glucose levels (p=0.002). Compared with subjects without sleep apnea, patients with severe OSA had significantly higher odds for NCEP ATP III risk higher than 10% (moderately high and high cardiovascular risk) (odds ratio: 4.06, 95% confidence interval: 1.02-16.25, p=0.048) after adjustment for body mass index and HOMA-IR. CONCLUSIONS These findings suggest that severe OSA is related to higher cardiovascular risk independently of obesity and insulin resistance.
Financially Qualified Members in an Upper Echelon and Their Relationship with Corporate Sustainability: Evidence from an Emerging Economy

Non-observable board diversity is an important organizational strategy for improving the long-term growth and survivability of firms. The involvement of corporate sustainability (CS) in top management teams has led to effective boards. By using agency theory, we stress how financially qualified directors (FQD) in audit committees (ACs) may positively or negatively affect the practice of earnings management (EM). We also use various theories to explain how a powerful chief executive officer (CEO) complicates the effectiveness of AC and reduces their ability to detect EM practices. Using a sample of 1020 firm-year observations representing 204 non-financial listed Pakistani firms during 2013–2017, we find that the presence of FQD on the AC is associated with lower levels of EM. Our analysis shows that this effect is driven by the level of FQDs’ accounting knowledge.
In vitro Activity of Daptomycin versus Linezolid and Vancomycin against Gram-Positive Uropathogens and Ampicillin against Enterococci, Causing Complicated Urinary Tract Infections

Objectives: The existing therapeutic options for complicated urinary tract infections (UTI) caused by gram-positive uropathogens are not always optimal. Therefore, newer antimicrobials have to be assessed. Methods: The antimicrobial activity of daptomycin was tested versus linezolid, vancomycin, and ampicillin (enterococci on ly), against pathogens from three different collections: (1) Uropathogens from hospitalized urological patients with complicated and/or hospital-acquired UTIs of the Urologic Clinic, Hospital St. Elisabeth, Straubing. (2) Uropathogens from a multicenter study comprising 37 urological centers throughout Germany. (3) Methicillin-resistant Staphylococcus aureus (MRSA) isolates of patients and staff within the Hospital St. Elisabeth, Straubing. Genotyping of the latter isolates was performed by pulsed-field gel electrophoresis. The minimal inhibitory concentrations (MIC) of daptomycin, linezolid, vancomycin, and ampicillin (only tested against enterococci) were determined by an agar dilution method using a multipointer with an inoculum of 104 CFU per point. Results: For all methicillin-susceptible Staphylococcus aureus (n = 25), MRSA (n = 49), methicillin-susceptible coagulase-negative staphylococci (n = 129), methicillin-resistant coagulase-negative staphylococci (n = 33), for Enterococcus faecalis (n = 289), and for Enterococcus faecium (n = 4) the MICs ranged up to 2 mg/l (daptomycin, linezolid), up to 4 mg/l (vancomycin), and up to 8 mg/l (ampicillin, enterococci only) indicating that all strains were susceptible to the antibiotics tested. Conclusions: According to the in vitro activity daptomycin may be considered a promising antibacterial agent for the treatment of complicated UTI caused by gram-positive uropathogens. Thus, daptomycin should be evaluated in a clinical study
Multigroup validation of the service quality, customer satisfaction and performance links in higher education

ABSTRACT The notion of ‘students as customers’ continues to be prominent, yet is insufficiently explored, especially from the standpoint of various stakeholders. To address this inadequacy, the present study employs a multigroup analysis of the service profit chain (SPC) model in higher education (HE). Its purpose is to examine the complete SPC model regarding stakeholder perceptions in order to inform its validation and implementation. A cross-sectional survey was employed in order to enable multigroup comparison of a comprehensive research model on subsamples of employees and students by means of structural equation modeling (SEM). Results provide support for the proposed SPC model within the sample of vocational colleges. Besides strongly linked constructs (quality–satisfaction–loyalty), some notable weaknesses (cracked ‘satisfaction mirror’) are found. Multigroup analysis also indicates some important differences between employees and students. Implications are provided for strategic service management in HE, which should acknowledge the differences among stakeholder perceptions.
Factors affecting the adoption of mobile banking: Sample of Turkey

Rapid developments in communication technologies make fundamental changes in the behaviour of people while performing basic tasks. Mobile banking (m-banking) as an innovative product of mobile industry is becoming more common to reduce and manage time-intensive banking affairs. Understanding the primary determinants of m-banking adoption is significant for banks and users. This study investigates seven factors that affect implementation and adoption of m-banking by Turkish customers. Perceived usefulness, perceived ease of use, security and privacy, compatibility, social influence, facilitating conditions and perceived cost were measured to identify their predictor roles for the use of m-banking. 128 valid data were collected in order to test our conceptual model. Seven hypotheses were tested. It was found that perceived usefulness, compatibility, and social influence have positive impact on m-banking adoption in Turkey.
A novel UWB wearable icon-type textile antenna for WBAN applications

A novel Ultra Wideband (UWB) wearable textile icon-type antenna is presented for WBAN applications. It comprises of radiating patch which is hexagonal in shape and partial ground plane. The design geometry is optimized to attain wider bandwidth in the UWB frequency ranges. Square shaped notch is introduced on the ground and unique slots on radiator are also introduced. Entire slots represent the “Power” icon. The proposed antenna dimension is 40 × 34 × 2.7 mm3 which cover bandwidth of 16.86 GHz. The proposed antenna performances are analyzed by Computer Simulation Technology (CST).
Fusion of background estimation approaches for motion detection in non-static backgrounds

Detection of moving objects is a fundamental task in video based surveillance and security applications. Many detection systems use background estimation methods to model the observed environment. In outdoor surveillance, moving backgrounds (waving trees, clutter) and illumination changes (weather changes, reflections, etc.) are the major challenges for background modelling and the development of a single model that fulfils all these requirements is usually not possible. In this paper we present a background estimation technique for motion detection in non-static backgrounds that overcomes this problem. We introduce an enhanced background estimation architecture with a long-term model and a short-term model. Our system showed that fusion of the detections of these two complementary approaches, improves the quality and reliability of the detection results.
Methods for translating ICTs’ survey questionnaire into French and Bambara

Researchers have used many instruments to gather data on the use of Information and Communication Technology to disseminate information on agricultural inputs towards farmers. These instruments are in English and based on some theories. The Technology Acceptance Model (TAM), the Diffusion of Innovation Theory (DOI) and the Unified Theory of Acceptance and Use of Technology (UTAUT) are the three most popular contemporary technology acceptance models. For other speaking languages especially French and Bambara, there is a need to translate. The increasing need for non-English data collection instruments and other survey materials has clearly given recent figures. Despite the availability of tools for translation, the DOI’s instrument has been barely translated into French and Bambara. In this paper, we used an adaptation method to translate the DOI’s instrument into French and Bambara. We produced a method for translating English survey questionnaire into French and Bambara. The method specifies and describes five steps, which are prepare, translate, pretest, revise and document.