Miracle-dz/UniFAR-FTUs huggingface dataset:
Assaying History: Creating Temporal Junctions through Urban Exploration

This paper discusses the role of encounters with the past in the practice of urban exploration through ethnographic research undertaken with communities of urban explorers. Urban exploration is an activity intimately connected with places that have largely reached the end of their capitalist use-life. In this paper I argue that the practice enticingly complicates understandings of places by unveiling unexpected material traces and immaterial affordances that build resilient personal attachments where the ‘present’ tangibly intersects with the ‘past’. In the process urban exploration exposes possibilities for a cultural use-life of abandoned buildings beyond the event of abandonment, with or without formal historical interpretation.
Single and double ionization of helium by fast antiproton and proton impact.

The first ion-atom--collision data obtained with antiprotons are presented. We measured the single- and double-ionization cross section for 0.5-5-MeV antiprotons and protons colliding with helium. For ion energies above --2 MeV, the single-ionization cross section is the same for protons and antiprotons. However, surprisingly, the double-ionization cross section for antiprotons is approximately a factor of 2 larger than that for protons. The present data constitute a challenge for future theoretical models of charged-particle--atom collisions.
Impact of nurses clothing on anxiety of hospitalised children.

AIM To investigate anxiety levels in two groups of children exposed to nurses with white vs. coloured clothing in a university hospital in Iran. BACKGROUND Hospitalisation causes anxiety in children and it is documented that nurses have an important role in alleviating children's distress and anxiety. Nurses characteristics, including their clothing is a factor that affects quality of care through child-nurse relationship. DESIGN Clinical trial. METHODS Children (n = 92) aged 7-15 years old hospitalised for 3-5 days in paediatric surgery ward were exposed to nurses in white or coloured clothing. Children's anxiety was assessed on admission and at discharge using Revised Children's Manifest Anxiety Scale. RESULTS Children exposed to white nursing uniforms showed higher anxiety levels compared with children exposed to coloured nursing clothing (p < or = 0.05). Besides coloured nursing clothing, female sex, age >11 years old (guidance school) and living in families with more than four members were predictors of lower global anxiety scores. CONCLUSION Providing a child-friendly environment through colourful nursing clothing can promote nurses' relationship with hospitalised children. This can satisfy children's expectations of the nursing care and alleviates the need for meeting ideals of nursing care through wearing a white nursing uniform provided that standards of nursing care are favoured. RELEVANCE TO CLINICAL PRACTICE Using colourful nursing clothing in paediatric wards reduces anxiety as a psychological parameter which delays improvement and provides a child-friendly environment that helps promotion of quality of nursing care.
High Intestinal and Systemic Levels of Interleukin-23/T-Helper 17 Pathway in Chinese Patients with Inflammatory Bowel Disease

Interleukin-23/T-helper 17 (IL-23/Th17) pathway plays a key role in the pathogenesis of inflammatory bowel disease (IBD), but little is known about its expression in Chinese population. In this study, we investigated the mRNA and protein levels of IL-12p40, tumor necrosis factor-like cytokine 1A (TL1A), Janus kinase 2 (JAK2), and IL-23R both locally and systemically in Chinese IBD patients. Our results indicated that the mRNA levels of IL-12p40 and TL1A were increased in ulcerative colitis (UC) patients. Furthermore, serum IL-12p40 and TL1A levels were higher in active UC patients, especially in patients with disease course less than 1.25 years or initial onset. No correlation was found between the genotype and serum levels of IL-12p40 or TL1A in UC patients. Additionally, the mRNA and protein expression of JAK2 and IL-23R were increased in UC and Crohn's disease (CD) patients. Taken together, our results provided evidence that IL-23/Th17 pathway genes may represent important biomarkers of active stage of IBD and serve as novel therapeutic targets for IBD in Chinese population.
The Problem of Exercise Adherence: Fighting Sloth in Nations With Market Economies

This paper overviews the problem of physical inactivity from the perspective of exercise adherence. Five conundrums are described that have retarded advances in knowledge about the causal determinants of physical activity and successful internenlions that increase long-term physical activity and exercise adherence: (a) The Revolving Door (i.e., adoption vs. maintenance); (b) Marketing Change: What is the Message ? (e.g., social marketing vs. product marketing; (c) Blind Intervention (i.e., what are the mediators of physical activity? ); (d) Premature Theory (e.g., the fallacy of linear modeling and the promise of structural covariance modeling); and (e)The Missing Dependent Vdriahle (i.e., defining and measuring physical activity).
A COMPARATIVE STUDY OF THE PERFORMANCE OF SAUDI MUTUAL FUNDS

This study examines the performance of 21 Saudi mutual funds using the CAPM and downside CAPM D-CAPM models over the period 2005-2011. Initially equity fund performance is examined against two benchmarks TASI and the GCCI Islamic index utilizing the traditional beta and CAPM performance evaluation measures. The evaluation is then replicated utilizing the downside beta and other tests of funds’ performance derived from the CAPM in the down side framework. The results indicate that the downside beta could be more relevant in terms of its higher explanatory power than the traditional beta and thus CAPM in the downside framework could be more relevant to report on funds’ performance in this emerging market. After exploring the aggregate performance by forming two fund portfolios; one representing the average Islamic mutual fund and the other is the average conventional fund, to examine the performance of the Islamic mutual funds portfolio compared to its conventional peers and to the overall market, the study finds, on average, Islamic mutual funds in outperform conventional mutual funds and the market portfolio. The study concludes that it is equally important for practitioners in emerging markets, to report performance using both CAPM measures and D-CAPM measures and if differences exist, then the D-CAPM could be the superior measure because of its suitability to the asymmetrical distribution of returns existing in emerging markets in general.
Building your self: a sensemaking approach to expatriates’ adjustment to ethical challenges

Purpose - – The purpose of this paper is to understand the behaviours described by expatriates (“what expatriates say they do”) when they are pressed for adjustment and, at the same time, they feel ethically challenged. Design/methodology/approach - – The authors interviewed 52 expatriates from the European Union working in Sub-Saharan Africa who were immersed in what was considered by them to be an ethically challenging context or situation while they were in the process of adjusting to their international assignment. The authors conducted a reflexive qualitative analysis between the data and existing literature. Findings - – The authors found that the feeling of moral discomfort that causes the perception of an ethical challenge is triggered by an event that contrasts with the expatriates’ notion of morals. After feeling ethically challenged, expatriates engage in a sensemaking process that is hinged in an “intended future identity”. Research limitations/implications - – The authors contribute to the literature by stressing the ethical dimension of adjustment. The authors complement the normative approaches to ethical decision making in international contexts. The research identifies a set of events that are considered as ethical challenges by business expatriates. Practical implications - – The research opens the possibility to anticipate and manage potential conflicts, thus minimizing the probability of expatriation failure. Early knowledge about an expatriate's intended future identity can provide relevant information concerning the probable type of adjustment problems s/he will face. Originality/value - – The research combines two hitherto separate streams of literature – expatriate adjustment and ethical decision making in international contexts – to open the possibility of ethical adjustment. This is supported by a sensemaking process that is also grounded in future intentions, and not only in past experiences and present signals.
TrpA1 Regulates Thermal Nociception in Drosophila

Pain is a significant medical concern and represents a major unmet clinical need. The ability to perceive and react to tissue-damaging stimuli is essential in order to maintain bodily integrity in the face of environmental danger. To prevent damage the systems that detect noxious stimuli are therefore under strict evolutionary pressure. We developed a high-throughput behavioral method to identify genes contributing to thermal nociception in the fruit fly and have reported a large-scale screen that identified the Ca2+ channel straightjacket (stj) as a conserved regulator of thermal nociception. Here we present the minimal anatomical and neuronal requirements for Drosophila to avoid noxious heat in our novel behavioral paradigm. Bioinformatics analysis of our whole genome data set revealed 23 genes implicated in Ca2+ signaling that are required for noxious heat avoidance. One of these genes, the conserved thermoreceptor TrpA1, was confirmed as a bona fide “pain” gene in both adult and larval fly nociception paradigms. The nociceptive function of TrpA1 required expression within the Drosophila nervous system, specifically within nociceptive multi-dendritic (MD) sensory neurons. Therefore, our analysis identifies the channel TRPA1 as a conserved regulator of nociception.
Hunting and Gathering

Among human foragers, males and females target different foods and share them. Some view this division of labor as a cooperative enterprise to maximize household benefits; others question men's foraging goals. Women tend to target reliable foods. Men tend to target energy-dense foods that are difficult to acquire and are shared widely outside the household, perhaps to advertise their phenotypic quality to potential mates and allies via a costly, and thus hard to fake, signal. An analysis of variation in sex-specific foraging was conducted to investigate its causes and origins. There is less division of labor in less seasonal, more productive habitats where males do more gathering. This suggests males respond more as optimal foragers than maximal signalers. The division of labor likely evolved after pair bonds, and after gathering technology became efficient enough to provision others, allowing males to specialize in foods with the greatest trade value with females.
The Effects on Growth of Commodity Price Uncertainty and Shocks

The author estimates the effects on growth of commodity price shocks, and uncertainty within an established empirical growth model. Ex-post shocks, and ex-ante uncertainty have been treated in the empirical literature as if they were synonymous. But they are distinct concepts, and it is both theoretically, and empirically inappropriate to treat them as synonymous. He shows that the interaction between policy, and aid is robust to the inclusion of variables capturing commodity price movements. More important, his approach departs in three ways from earlier empirical studies of the subject: 1) It deals with issues of endogeneity, without incurring an excessive loss of efficiency. 2) It defines the dependent variable to allow an assessment of the longer-term implications of temporary trade shocks. 3) It imposes no priors on how commodity price movements affect growth, but compares and contrasts a range of competing shock, and uncertainty specifications. The author resolves the disagreement about the long-run effect of positive shocks on growth, finding that positive shocks have no long-run impact on growth (that windfalls from trade shocks do not translate into sustainable increases in income). He shows that negative shocks have large, highly significant, and negative effects on growth, but that commodity price uncertainty does not affect growth.
Iron oxide induced enhancement of mucoadhesive potential of Eudragit RLPO: formulation, evaluation and optimization of mucoadhesive drug delivery system

Objectives: The objective of the study was to investigate the effect of iron oxide in the development of mucoadhesive tablets of cinnarizine using Eudragit RLPO polymer. A simplex lattice design was employed for optimizing the drug delivery system. Methods: Different concentrations of Eudragit RLPO (X1), iron oxide (X2) and PVP K 30 (X3) were taken as independent variables and mucoadhesive strength, t50%, t90%, MDT and tablet tensile strength were the selected response variables. Contour and 3D plots were drawn to portray the relationship between independent and response variables. Ex vivo studies were performed for the determination of mucoadhesive strength of formulated tablets employing texture analyzer. ATR-FTR, DSC and zeta potential determination were conducted for drug-excipient and ionic interaction studies. Results: Friability, hardness and tensile strength of mucoadhesive tablet formulation were found to be 0.42 ± 0.21%, 3.93 ± 1.57 kg/cm2 and 0.65 ± 0.26 mN/m2, respectively. Mucoadhesive strength was found to be ranging between 5.75 ± 4.41 and 42.85 ± 3.94 g. Value of release exponent (n) was found to be 0.65 ± 0.22, indicating anomalous drug release behavior from the formulations. Numerical optimization using the desirability approach was employed for developing optimized formulation by setting constraints of the dependent and independent variables. The mucoadhesive tablet formulation composition consisting of 8.58% w/w Eudragit RLPO, 7.02% w/w iron oxide and 7.26% w/w PVP K 30 fulfilled maximum requirements of an optimum formulation with better regulation of the selected constraints. Conclusions: Eudragit RLPO and iron oxide combination showed high level potential for fabricating gastroretentive as well as mucoadhesive drug delivery systems.
Control of Nonlinear Bifurcating Systems

{ Bifurcation analysis provides a methodology for the study of the changes of stability behavior of nonlinear and parameter dependent systems. The inception of bifurcations is associated with systems exhibiting critical modes. Consequently, stabilization of critical systems can be considered as control of the underlying bifurcations. Based on bifurcation equations and the center manifold theorem, and depending on controllability characteristics of critical modes, diierent control laws to achieve steady and/or periodic state stabilization are derived.
Putative Membrane-Bound Transporters MFSD14A and MFSD14B Are Neuronal and Affected by Nutrient Availability

Characterization of orphan transporters is of importance due to their involvement in cellular homeostasis but also in pharmacokinetics and pharmacodynamics. The tissue and cellular localization, as well as function, is still unknown for many of the solute carriers belonging to the major facilitator superfamily (MFS) Pfam clan. Here, we have characterized two putative novel transporters MFSD14A (HIAT1) and MFSD14B (HIATL1) in the mouse central nervous system and found protein staining throughout the adult mouse brain. Both transporters localized to neurons and MFSD14A co-localized with the Golgi marker Giantin in primary embryonic cortex cultures, while MFSD14B staining co-localized with an endoplasmic retention marker, KDEL. Based on phylogenetic clustering analyses, we predict both to have organic substrate profiles, and possible involvement in energy homeostasis. Therefore, we monitored gene regulation changes in mouse embryonic primary cultures after amino acid starvations and found both transporters to be upregulated after 3 h of starvation. Interestingly, in mice subjected to 24 h of food starvation, both transporters were downregulated in the hypothalamus, while Mfsd14a was also downregulated in the brainstem. In addition, in mice fed a high fat diet (HFD), upregulation of both transporters was seen in the striatum. Both MFSD14A and MFSD14B were intracellular neuronal membrane-bound proteins, expressed in the Golgi and Endoplasmic reticulum, affected by both starvation and HFD to varying degree in the mouse brain.
Complete Genome Sequence of Fish Pathogen Aeromonas hydrophila AL06-06

ABSTRACT Aeromonas hydrophila occurs in freshwater environments and infects fish and mammals. Here, we report the complete genome sequence of Aeromonas hydrophila AL06-06, which was isolated from diseased goldfish and is being used for comparative genomic studies with A. hydrophila strains that cause bacterial septicemia in channel catfish aquaculture.
The relationship between needs and job attitudes in South Korea and Germany

Purpose – The present study aims to analyze the predictive value of three motivational dispositions (need for achievement, need for affiliation, and need for power) for job involvement and organizational commitment and to investigate cross‐cultural differences between Germany and South Korea between these predictions.Design/methodology/approach – A sample of South‐Korean (N=209) and German (n=198) executive MBA students was surveyed. Using multi‐group structural equation modeling, the associations between the three needs and JI and OC and cross‐cultural differences in these associations are investigated. In addition, a test is conductedd for cross‐cultural equivalence of the measures as an important prerequisite of quantitative analyses.Findings – The results reveal that need for achievement and need for power are related to JI but that only need for achievement is related to OC. In addition, significant differences were not found across either country in these relationships. Tests of cross‐cultural equiv.
Numerical modelling of erbium (III) doped Q-switched fibre lasers

We consider the modelling and design of high power ZBLAN glass based erbium (III) doped fibre lasers operating in the Q-switched regime. The detailed description of all models used is given. The results are calculated for a standard set of modelling parameters used in the literature, which correspond to a commercially available erbium doped ZBLAN fibre. We apply a time domain method which uses a steady state model to obtain the approximation of the initial conditions and study the dependence of the pulse shape on laser operating parameters.
Pedigree-free animal models: the relatedness matrix reloaded

Animal models typically require a known genetic pedigree to estimate quantitative genetic parameters. Here we test whether animal models can alternatively be based on estimates of relatedness derived entirely from molecular marker data. Our case study is the morphology of a wild bird population, for which we report estimates of the genetic variance–covariance matrices (G) of six morphological traits using three methods: the traditional animal model; a molecular marker-based approach to estimate heritability based on Ritland's pairwise regression method; and a new approach using a molecular genealogy arranged in a relatedness matrix (R) to replace the pedigree in an animal model. Using the traditional animal model, we found significant genetic variance for all six traits and positive genetic covariance among traits. The pairwise regression method did not return reliable estimates of quantitative genetic parameters in this population, with estimates of genetic variance and covariance typically being very small or negative. In contrast, we found mixed evidence for the use of the pedigree-free animal model. Similar to the pairwise regression method, the pedigree-free approach performed poorly when the full-rank R matrix based on the molecular genealogy was employed. However, performance improved substantially when we reduced the dimensionality of the R matrix in order to maximize the signal to noise ratio. Using reduced-rank R matrices generated estimates of genetic variance that were much closer to those from the traditional model. Nevertheless, this method was less reliable at estimating covariances, which were often estimated to be negative. Taken together, these results suggest that pedigree-free animal models can recover quantitative genetic information, although the signal remains relatively weak. It remains to be determined whether this problem can be overcome by the use of a more powerful battery of molecular markers and improved methods for reconstructing genealogies.
Developing Metadiscourse: Building Mathematical Discussions in an Urban Elementary Classroom

This study aims to understand an effective model of mathematical meaning-making in classrooms with a majority of Latina/o English learners. This analysis is grounded in the cultural-historical ideas that learning is mediated through organized activity and learners show greater awareness of problem-solving strategies through metadiscourse practices. In particular, we focus on the use of discussion builder stems and OK/Pitfall stories to mediate discussions and develop metacognitive awareness for English learners. RésuméCette étude vise à décrire un modèle efficace pour l’élaboration des signifiés mathématiques dans des classes à majorité d’élèves d’origine sud-américaine en situation d’apprentissage de l’anglais. Cette analyse se fonde sur certaines notions culturelles et historiques selon lesquelles l’apprentissage peut faire l’objet d’une médiation par le biais d’activités organisées, et que les apprenants ont une meilleure connaissance des stratégies de résolution de problèmes grâce à certaines pratiques de métalangage. En particulier, nous centrons notre attention sur l’utilisation d’éléments de discussion et de récits acceptables/inacceptables, permettant une médiation des discussions et une meilleure sensibilisation métacognitive chez les élèves en situation d’apprentissage de l’anglais.
SYSTEM PARAMETERS FOR THE ECLIPSING B-STAR BINARY HD 42401

I present results from an optical spectroscopic investigation of the binary system HD 42401 (V1388 Ori; B2.5 IV–V + B3 V). A combined analysis of V-band photometry and radial velocities indicates that the system has an orbital period of 2.18706 ± 0.00005 days and an inclination of 75. °5 ± 0. °2. This solution yields masses and radii of M1 = 7.42 ± 0.08 M☉ and R1 = 5.60 ± 0.04 R☉ for the primary and M2 = 5.16 ± 0.03 M☉ and R2 = 3.76 ± 0.03 R☉ for the secondary. Based on the position of the two stars plotted on a theoretical Hertzsprung–Russell diagram, I find that the age of the system is ≳ 25 Myr and that both stars appear overluminous for their masses compared to single-star evolutionary tracks. A fit of the spectral energy distribution based on photometry from the literature yields a distance of 832 ± 89 pc to HD 42401.
Electrocatalytic Determination of Glucose in a Ringer's Solution by Pulse-Voltammetry

Improvement of the electrocatalytic method of glucose determination was achieved by applying the pulse voltammetry technique. This technique, compared. to previously applied cyclic voltammetry, enhances selectivity of a platinum-black working electrode for glucose measurement. A low catalytic load working electrode has been used which is less susceptible to poisoning and has longer term stability. With cyclic voltammetry previously applied, those electrodes were limited by their narrow concentration range for glucose detection. By applying a pulsing technique, these electrodes exhibit linearity up to a glucose concentration 200 mg/dl with correlation coefficients greater than 0.9. The pulse voltammetry diminishes interference by low molecular weight serum components such as serum urea. Concentrations from 20. to 40 mg/di had an interference of 4 percent compared to 40 percent with cyclic voltammetry. Further investigations are carried on to adopt pulse voltammetry for direct measurements of glucose in body fluids.