Miracle-dz/UniFAR-FTUs huggingface dataset:
Uncovering why Inbound Marketing has Become so Popular for Communication agencies

In introduction, the topic of this dissertation is ‘why has Inbound Marketing increased in popularity with communication agencies in recent years? ’ The context of this dissertation is establishing why many communication agencies have defected from using traditional, outbound marketing methods in recent years in favour of Inbound Marketing techniques such as e-stores and social media platforms. The central issue of this dissertation concerns identifying the main reasons why an increasing number of communication agencies have started using Inbound Marketing techniques in recent years. Due to the revolutionization of the internet, Inbound Marketing techniques have become increasingly popular with modern organisations (Xiaoge, 2016). In the communication agency industry, Inbound Marketing excellence is a strategic capability which has become especially well sought after as firms try to gain a competitive advantage in a fiercely contested industry (Xiaoge, 2016). This research topic has principally been chosen as even though the topic of marketing has been highly researched in the last number of decades, this current iteration of marketing called Inbound Marketing has little academic research performed on it. A further reason why this topic was chosen is because the researcher has direct access to communication agency owners. To find out exactly why Inbound Marketing has become so popular, it is important to gain an understanding of how to approach the research itself. This was achieved by first carrying out an extensive literature review containing some key theories and concepts from the subject of marketing. The researcher’s primary field investigations principally involved carrying out rounds of in depth interviews with 5 different communication agency owners. A qualitative thematic analysis was then used to interpret the results of these to pick out the key themes and patterns which emerged from the interview transcripts.
An examination of the relationships between consumer benefits, satisfaction, and loyalty in the purchase of retail store branded products

The purpose of this study was to investigate the relationships between consumer benefits (i.e., utilitarian and hedonic) and consumer satisfaction, loyalty, and word of mouth communication in a retail store branded product context. The independent variables examined were the utilitarian and hedonic consumer benefits associated· with a retail store branded product purchase. The dependent variables in the study included retail store brand satisfaction, attitudinal loyalty, behavioral loyalty (share of purchases), and word of mouth communication. A non-experimental survey research design was used to collect data from a college student sample at a major university in the southeast. The final sample consisted of 276 students. The survey included 34 items that measured the independent and dependent variables, as well as demographic questions. Confirmatory factor analysis (CFA) and structural equation modeling (SEM) were used to evaluate five hypotheses. The overall fit of the final structural equation model was supported by a comparative fit index (CFI) of 0.941. Significant positive relationships were found between retail store brand utilitarian/hedonic consumer benefits and satisfaction, satisfaction and attitudinal loyalty, and attitudinal loyalty and word of mouth communication. Non-significant relationships were found between retail store brand satisfaction and word of mouth communication, and between retail store brand satisfaction and
Teaching through movies in a multicultural scenario: overcoming cultural barriers through emotions and reflection.

Editor’s Note: In this column, teachers who are currently using literary and artistic materials as part of their curricula will briefly summarize specific works, delineate their purposes and goals in using these media, describe their audience and teaching strategies, discuss their methods of evaluation, and speculate about the impact of these teaching tools on learners (and teachers). Submissions should be three to five double-spaced pages with a minimum of references. Send your submissions to me at University of California, Irvine, Department of Family Medicine, 101 City Drive South, Building 200, Room 512, Route 81, Orange, CA 92868-3298. 949-824-3748. Fax: 714-456-7984. jfshapir@uci.edu.
New Functions of the Major Histocompatibility Complex Class II-Specific Transcription Factor RFXANK Revealed by a High-Resolution Mutagenesis Study

ABSTRACT The transcription factors RFX and CIITA are major players in regulation of the expression of all classical and nonclassical major histocompatibility complex class II (MHC-II) genes. RFX nucleates the formation of a multiprotein complex, called the MHC-II enhanceosome, on MHC-II promoters. Assembly of this enhanceosome is an obligatory step for recruitment of the coactivator CIITA and thus for activation of MHC-II gene transcription. We have analyzed the function of the ankyrin repeat-containing protein RFXANK, which forms the heterotrimeric RFX complex together with RFX5 and RFXAP. We discovered that ANKRA2, the closest paralogue of RFXANK, can substitute for RFXANK in the activation of MHC-II genes and that this ability is mediated by its ankyrin repeat domain (ARD). This finding provided the basis for a high-resolution structure-function analysis of the ARD of RFXANK, which allowed us to map the RFX5 interaction domain and residues critical for assembly of the RFX complex. We also found that mutations in the fourth ankyrin repeat of RFXANK abolish assembly of the enhanceosome on MHC-II promoters in vivo but not in vitro, suggesting a new role of RFXANK in facilitating promoter occupation in the context of chromatin.
Combination of primers used to amplify open reading frame of the respective genes by real-time and semiquantitative PCR

Veedamali S. Subramanian, Sandeep B. Subramanya, Hidekazu Tsukamoto, and Hamid M. Said Departments of Medicine, Physiology, and Biophysics, University of California, Irvine; Department of Veterans Affairs Medical Center, Long Beach; Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles; and Department of Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California
Cloning and characterization of the Yarrowia lipolytica squalene synthase (SQS1) gene and functional complementation of the Saccharomyces cerevisiae erg9 mutation

The squalene synthase (SQS) gene encodes a key regulatory enzyme, farnesyl‐diphosphate farnesyltransferase (EC 2.5.1.21), in sterol biosynthesis. The SQS1 gene was isolated from a subgenomic library of the industrially important yeast Yarrowia lipolytica, using PCR‐generated probes. Probes were based on conserved regions of homologues from different organisms. The complete nucleotide sequence of the coding region and the corresponding amino acid sequence were determined. The sequences showed extensive homologies with squalene synthase genes and enzymes from a number of other organisms and extreme amino acid conservation within the binding and catalytic domains. Direct cloning of a 4.3 kb genomic Y. lipolytica fragment, also comprising its own promoter and terminator sequences, into autonomously replicating plasmid YEp352 and subsequent transformation of a Saccharomyces cerevisiae mutant strain with relevant erg9: ura3–1 markers, resulted in functional complementation of these deficiencies, although Northern blot analyses did not reveal a unique full‐length messenger. The availability of the Y. lipolytica SQS1 gene (GenBank Accession No. AF092497) offers prospects for metabolic engineering of the isoprenoid and sterol biosynthetic pathways. Copyright © 2000 John Wiley & Sons, Ltd.
Look at that body! How anthropomorphic package shapes systematically appeal to consumers

ABSTRACT The manuscript identifies how anthropomorphized packages elicit aesthetic appeal. Specifically, we shed light on the effectiveness of applying evolutionary relevant shapes, which are figures of attractive female (i.e. hourglass-shaped) and male (i.e. V-shaped) bodies, to consumer goods’ package design. Results of two lexical decision tasks (Study 1a and 1b) show that when consumers observe a package shaped after an ideal body figure, the mental schema of the human body spontaneously becomes activated. In turn, accessible knowledge of the activated schema influences consumer responses. Two studies (Studies 2a and 2b) demonstrate that packages of gender-neutral consumer goods shaped after an ideal body figure generate aesthetic appeal and favourable product evaluations. A final study (Study 3) reveals that when the package of a gender-specific consumer good is being anthropomorphized, a gender-schema congruity effect occurs: aesthetic appeal is elicited when the package shape is congruent with the target user's ideal body figure.
An approach for system identification in unmanned surface vehicles

In this study, a system identification methodology is introduced to determine the model parameters of unmanned surface vehicles. The proposed identification scheme is based on sequencing the experiments according to their capabilities to identify the model parameters. In each experiment, the parameters to be found are updated and the results are validated before ascertaining the final value. A procedure to complete the identification work in an experiment, namely the required post-processing, the optimization routines, the cost function evaluations are defined and discussed. The final parameter set is validated in random motion tests with rich motion content. It has been observed that the proposed method elicits a parameter identification with remarkable success.
When Sexuality is in a Research Topic! The Methodological Challenges in Sexuality and Street Healing Research in Bangladesh

This paper is a bridge between two studies by the author: (i) completed MA research; and (ii) on-going PhD research, on male sexual health and the street healing system in Bangladesh. Street healing, a traditional healing system in Bangladesh, is at the centre of the studies. This is a popular form of folk healing in Bangladesh, where male impotency is a central issue. The author has been researching street healing to understand male sexual health-seeking behaviour in Bangladesh. In this paper, the author brings in experiences from his MA research to explore the challenges of studying sexuality and street healing in Bangladesh and concludes by describing his plan to address those issues in his on-going PhD research.
The Destruction and Recreation of the X-Ray Corona in a Changing-look Active Galactic Nucleus

We present the drastic transformation of the X-ray properties of the active galactic nucleus (AGN) 1ES 1927+654, following a changing-look event. After the optical/ultraviolet outburst the power-law component, produced in the X-ray corona, disappeared, and the spectrum of 1ES 1927+65 instead became dominated by a blackbody component (kT ∼ 80–120 eV). This implies that the X-ray corona, ubiquitously found in AGNs, was destroyed in the event. Our dense ∼450 days long X-ray monitoring shows that the source is extremely variable in the X-ray band. On long timescales the source varies up to ∼4 dex in ∼100 days, while on short timescales up to ∼2 dex in ∼8 hr. The luminosity of the source is found to first show a strong dip down to , and then a constant increase in luminosity to levels exceeding the pre-outburst level ≳300 days after the optical event detection, rising up asymptotically to . As the X-ray luminosity of the source increases, the X-ray corona is recreated, and a very steep power-law component (Γ ≃ 3) reappears, and dominates the emission for 0.3–2 keV luminosities , ∼300 days after the beginning of the event. We discuss possible origins of this event, and speculate that our observations could be explained by the interaction between the accretion flow and debris from a tidally disrupted star. Our results show that changing-look events can be associated with dramatic and rapid transformations of the innermost regions of accreting supermassive black holes.
The Relative Effectiveness Of Endorsers

ABSTRACT Using source-credibility and source-attractiveness models, this study examines the endorsement effectiveness of chief executive officers (ceos) and founders as compared with celebrities, especially when ceos and founders are not well-known or popular. Advertisements with ceos and founders are a fast-growing brand-endorsement tactic. Recent studies also indicate that ceos as business leaders influence consumers' purchase intention. This study's findings, based on a café brand and replicated for a hotel-and-pub company in the United Kingdom, indicate that when the identity of ceos and founders is signaled through their identity badge (i.e., their title and designation), consumers find an advertisement more effective than an advertisement with celebrities. Advertisements with founders as endorsers were found to be more effective for new products, whereas ceos as endorsers were more effective for existing products.
The Impact of the 4th Industrial Revolution on the High-Tech Industry

The challenges of the 4th Industrial Revolution (I40) entail new business models to improve customer value creation. So far, academic investigation into I40 has been extensively focused on large enterprises, and only marginally on SMEs. The present paper aims to answer to the following four research questions: How do manufacturing SMEs perceive the I40 phenomenon? How do manufacturing SMEs innovate their business models because of I40? How do manufacturing SMEs behave with their suppliers because of I40? How do manufacturing SMEs behave with their customers because of I40?
Quantification and real-time tracking of RNA in live cells using Sticky-flares

Significance Proper function of RNA is critical to the health and maintenance of a cell, and its misregulation plays a critical role in the development of many disorders. To date, the ability to study RNA has been severely limited; many analytical techniques focus only on quantifying expression levels of transcripts and are not capable of reporting on intracellular localization, which has emerged as a critical component of RNA function. Similarly, techniques capable of probing RNA localization only offer snapshots in fixed cells. Herein we introduce a novel nanoconjugate, termed the Sticky-flare, capable of reporting on both of these critical components in live cells, thereby gaining a more complete picture or RNA function than any analytical technique to date. We report a novel spherical nucleic acid (SNA) gold nanoparticle conjugate, termed the Sticky-flare, which enables facile quantification of RNA expression in live cells and spatiotemporal analysis of RNA transport and localization. The Sticky-flare is capable of entering live cells without the need for transfection agents and recognizing target RNA transcripts in a sequence-specific manner. On recognition, the Sticky-flare transfers a fluorophore-conjugated reporter to the transcript, resulting in a turning on of fluorescence in a quantifiable manner and the fluorescent labeling of targeted transcripts. The latter allows the RNA to be tracked via fluorescence microscopy as it is transported throughout the cell. We use this novel nanoconjugate to analyze the expression level and spatial distribution of β-actin mRNA in HeLa cells and to observe the real-time transport of β-actin mRNA in mouse embryonic fibroblasts. Furthermore, we investigate the application of Sticky-flares for tracking transcripts that undergo more extensive compartmentalization by fluorophore-labeling U1 small nuclear RNA and observing its distribution in the nucleus of live cells.
Lion: Listen online. Using GraphQL as a mediator for data integration and ingestion

Data integration is the task of providing a unified view of multiple data sources. These sources can be, and are typically, heterogeneous in their data model, data query language (DQL), and data manipulation language (DML). In this thesis is described a system called “Listen Online”, or Lion for short. Lion utilizes the GraphQL specification to provide integration for querying of web services. Lion provides a general structure by which arbitrary mediators can be used within a query. Lastly, by building on top of open source libraries, Lion provides the open source community with components that enable it to function in the form of GraphQL servers, visual layout libraries, and query builders.
From sets of equilibria to structures of interaction underlying binary games of strategic complements

Consider a setting in which agents can each take one of two ordered actions and in which the incentive of any given agent to take the high action is positively reinforced by the number of other agents that take it. Furthermore, assume that we don't know any other details about the game being played. What can we say about the details of the structure of the interaction between actions and incentives when we observe a set or a subset of all possible equilibria? In this paper we study 3 nested classes of games: (a) binary games of strategic complements; (b) games in (a) that admit a network representation: and (c) games in (b) in which the network is complete. Our main results are the following: It has long been established in the literature that the set of pure strategy Nash equilibria of any binary game of strategic complements among a set N of agents can be seen as a lattice on the set of all subsets of N under the partial order defined by the set inclusion relation. If the game happens to be strict in the sense that agents are never indifferent among outcomes (games in (a)), then the resulting lattice of equilibria satisfies a straightforward sparseness condition. (1) We show that, in fact, the games in (a) express all such lattices. (2) We characterize the collection of subsets of N that can be weakly expressed as the set of equilibria of some game of thresholds (games in (b)). (3) We characterize the collection of subsets of N that can be weakly expressed as the set of equilibria of some game of thresholds on the complete graph (games in (c)).
Kaposi's sarcoma in patients with and without human immunodeficiency virus infection, in a tertiary referral centre in Kenya

Abstract The clinical features of Kaposi's sarcoma (KS), in patients with and without HIV infection, were investigated in a tertiary referral centre in Kenya between 1997 and 1999. Although 186 cases were identified prospectively, the data analysis was restricted to the 91 (49%) cases who had pathological confirmation of Kaposi's sarcoma and documented HIV serostatus. Among these 91 subjects (58% of whom were male), the age-group holding the largest number of KS cases was that of individuals aged 31–40 years; most of the paediatric cases were aged 6–10 years. The ratio of HIV-seropositives to HIV-seronegatives was 8.5:1 for the adult cases and 0.9:1 for the paediatric. Of the signs and symptoms of Kaposi's sarcoma seen at presentation, only peripheral lympadenopathy was found to be significantly associated with underlying HIV infection (P = 0.05). The median survival was 104 days. It is apparent that, as the HIV epidemic advances in regions of the world with endemic KS, the clinical presentation and natural history of the endemic KS are blending with those of the epidemic or AIDS-associated disease, leading to a reduction in the mean age of the cases and a nearly identical incidence in men and women. In regions of the world where patients have ready access to such chemotherapy, the impact of treatment with highly active antiretroviral drugs on the incidence and natural history of KS has been dramatic. It will be important to monitor the clinico–pathological features of KS in the developing world, as more active antiretroviral regimens become available in clinical practice there.
Influence of patients’ age and sex and the mode of administration on results from the NHS Friends and Family Test of patient experience

Objective To investigate the impact of demographic factors (patients’ age and sex) and of the mode of administration of a national patient experience questionnaire in England: the NHS Friends and Family Test. Methods Secondary analysis of April–August 2013 data collected using a mixed mode approach from 38,998 inpatients and 29,610 emergency department attendees at 429 wards or units in 32 hospitals. Multilevel models were applied with responses from wards nested within hospitals and trusts. Age, sex and mode of administration were entered as main effects. Results There were consistent differences in response for patients and emergency department attendees related to their age and sex. Women gave less positive ratings than men, whilst the likelihood of positive responses increased with age except among the oldest age group (75 years and above). As regards mode of administration, online responses were significantly less positive than postcard responses: the mean differences in score were 22.0 points for inpatients (95% confidence interval 27.3 to 16.7) and 18.0 points for emergency department attendees (29.0 to 7.0). Telephone responses were significantly more positive than postcard responses, with a mean difference of 9.2 (1.6–16.8) in the emergency department setting. Conclusions Data from the Friends and Family Test are vulnerable to bias from demographic factors and from the mode of administration. Comparisons between organisations should be avoided. Scores may be useful at a local level where the test is implemented consistently and patients’ demographic characteristics remain stable. Improving the utility of the Friends and Family Test nationally requires a standardised method for administration and adjustment of results for demographic characteristics.
Etude au séisme des structures élastoplastiques : Cas de l'oscillateur simple

Ce travail de these a pour ambition d’apporter quelques eclairages sur le comportement des structures inelastiques soumises a des sollicitations periodiques de type sismique. L’etude sera retreinte a un systeme a un degre de liberte. L’objectif de l’etude est de degager des zones comportementales de l’oscillateur reliees a la theorie moderne des systemes dynamiques non lineaires. Cette etude s’interesse donc a une loi de comportement simple elastoplastique dans un cadre dynamique : on peut ainsi parler de "Rheologie dynamique" pour caracteriser un tel oscillateur inelastique. Notre premiere motivation est d’analyser le comportement dynamique d’un oscillateur avec une technique utilisee dans le domaine des systemes dynamiques non reguliers. On procede a l'etude de la stabilite et de la dynamique d'un oscillateur elastoplastique symetrique non amorti. Cette etude a permis de lier les proprietes dynamiques (cycle limite…) aux caracteristiques mecaniques (adaptation, accomodation), et un diagramme de bifurcation est mis en evidence numeriquement. L'etude est enrichie par la suite par l'introduction d'un amortissement visqueux. Enfin, la dynamique d'un oscillateur elastoplastique parfait amorti et asymetrique, soumis a une excitation exterieure harmonique, est traitee. L'effet de rochet est ainsi mis en evidence. Ces analyses ont permis de proposer des recommandations qui peuvent certainement etre prises en compte, comme parametres supplementaires, dans la philosophie de conception sismique.