Miracle-dz/UniFAR-FTUs huggingface dataset:
1 2 Cognitive and Contextual Variables in Sexual Partner 3 and Relationship Perception 4

7 Abstract This study examined the effects of contextual and 8 cognitive variables for sexual protection on perceived social 9 relationship factors. University students (108 women and 108 10 men) read script-based narratives on sexual encounters in 11 which six variables were manipulated in two independent anal12 yses. In thefirst analysis, fourvariableswereevaluated: relational 13 context (stable, casual), condom use (yes, no), script terminus 14 (beginning,middle or end), and the rater’s sex. The dependent 15 variables were interpersonal perception of one of the charac16 tersof thenarrative, andexpectations regarding characteristics 17 and future of the relationship. In the second analysis, twoother 18 factorsweremanipulatedonly in the‘‘yes’’condomconditions: 19 communication strategy (verbal, non-verbal) and condom 20 proponent gender. Our findings corroborated other studies 21 where condom use was viewed as unromantic with less posi22 tive characteristics for relationships. Condom proponents, 23 especially male, were perceived as less romantic, particularly 24 whenproposing a condomnon-verbally at the beginningof the 25 encounter. However, the controlled variables enabled us to 26 propose ways of associating condom use with positive expec27 tations towards the proponent and the relationship itself. Roman28 ticism, expectation of sexual intercourse, emotional proximity, 29 and expectations of condom use in encounters where a condom 30 was proposed increasedwhen suggested by awoman, postponed 31 to the end of the encounter, and verballymentioned.We encour32 age women to take the lead in suggesting condom use, thus 33 empowering them since they do not have to wait for the male to 34 make the first move. 35 36
Intrinsic and Extrinsic Motivation as Attitude Factors towards Adoption of Accounting Information System (AIS) In Libyan SMEs

Though the relationship between users’s IT characteristics and behavioral intention of users to adoption information system continues to be important, conclusive evidence on user’s attitude contributing to enhance behavioral intention to adopt is rare. This study tests the influence of intrinsic and extrinsic motivation towards behavioral intention to adopt accounting information system in Libyan SMEs. Questionnaire was designed using closed interval measurement scale with proper care of designing the survey instruments. Results found support for the effect of user's attitude as mediator between IT characteristics and behavioral intention. Intrinsic motivation and extrinsic motivation factors of motivation model were found to have high impact in the form of attitude on owner's behavior to adopt AIS. Selecting the AIS adoption SMEs will follow have an effect on AIS implementation, along with organizational context, affecting the level of AIS implementation directly and indirectly through AIS adoption.
Identifying the factors affecting information sharing in supply chain - A systematic review of the literature

Information sharing is considered as one of the most important factors for successful supply chain management (SCM) as it lowers the degree of uncertainty, improves supply chain integration and coordination, mitigates the bullwhip effect and reduces the total costs. Information sharing and the development of strong relationships among supply chain partners have been frequently identified in the literature as a way to overcome SCM implementation barriers and to improve supply chain efficiency and effectiveness. While the advancement in information technology has made information sharing more efficient, the extent of information sharing among supply chain partners varies significantly. Studies have been conducted to identify the factors affecting information sharing in supply chain. These studies tend to focus only on a small number of factors. Therefore, a systematic approach is needed to investigate the full range of factors related to information sharing. A systematic review of the literature was carried out to identify the factors that enhance or impede information sharing in supply chains. Re-categorisation and evaluation of the identified factors was carried out to provide implications for supply chain managers and participants. The findings of the systematic review can be used for future empirical research to verify the identified factors in different contexts.
The Tumor Suppressor p 53 Down-Regulates Glucose Transporters GLUT 1 and GLUT 4 Gene Expression

Tumorigenesis is associated with enhanced cellular glucose uptake and increased metabolism. Because the p53 tumor suppressor is mutated in a large number of cancers, we evaluated whether p53 regulates expression of the GLUT1 and GLUT4 glucose transporter genes. Transient cotransfection of osteosarcoma-derived SaOS-2 cells, rhabdomyosarcoma-derived RD cells, and C2C12 myotubes with GLUT1-P-Luc or GLUT4-PLuc promoter-reporter constructs and wild-type p53 expression vectors dose dependently decreased both GLUT1 and GLUT4 promoter activity to approximately 50% of their basal levels. PG13-Luc activity, which was used as a positive control for functional p53 expression, was increased up to 250-fold by coexpression of wild-type p53. The inhibitory effect of wild-type p53 was greatly reduced or abolished when cells were transfected with p53 with mutations in amino acids 143, 248, or 273. A region spanning 66/ 163 bp of the GLUT4 promoter was both necessary and sufficient to mediate the inhibitory effects of p53. Furthermore, in vitro translated p53 protein was found to bind directly to two sequences in that region. p53-DNA binding was completely abolished by excess unlabeled probe but not by nonspecific DNA and was super-shifted by the addition of an anti-p53 antibody. Taken together, our data strongly suggest that wild-type p53 represses GLUT1 and GLUT4 gene transcription in a tissuespecific manner. Mutations within the DNA-binding domain of p53, which are usually associated with malignancy, were found to impair the repressive effect of p53 on transcriptional activity of the GLUT1 and GLUT4 gene promoters, thereby resulting in increased glucose metabolism and cell energy supply. This, in turn, would be predicted to facilitate tumor growth.
The Ghosting Technique Applied to Augmented Reality Visualization

Functional realism focuses on delivering to the user the best visual information from the target scene. The virtual scenes/objects do not need to behave or look like the real ones, but they need to help users in tasks execution. In this sense, this paper focuses on functional realism applied to Augmented Reality scenes. The technique presented here applies a visualization technique called Ghosting to generate an importance map from the real scene in order to blend in the virtual objects in a more adequate way. A careless augmentation can prejudice the user Augmented Reality based experience. The importance map is built from a saliency map, edge detection, super pixel representation and texture analysis. We present results in outdoor and indoor environments in order to prove the technique effectiveness.
Thinned Blood, Monkey Lungs, and the Cold Heart

In reviewing the history of cardiac surgery, the reader cannot help but be overwhelmed with admiration for those pioneering surgeons and scientists whose courageous innovations, untiring work, and difficult early clinical experiences finally made the heart a surgically accessible organ. The collaboration among engineers, physiologists, chemists, and surgeons serves as a model for medical progress. In this article, we will review the contributions to the field of open heart surgery that came from the University of Toronto in the very early days of this elusive goal. Although much remained within the experimental stage, the accomplishments described, nonetheless, exemplify the unique and untiring imagination of those involved at that time. This paper will review the major advances that were made in the 1930s in purifying a commercially available and safe extract of heparin, anticoagulation being the “key to open heart surgery,”1 as well as the experimental and clinical work in the late 1940s and early 1950s by two pioneering Canadian cardiac surgeons Dr. William T. Mustard (extracorporeal circulation at the Hospital for Sick Children) and Dr. Wilfred G. Bigelow (hypothermia at the Toronto General Hospital).
Does Board Structure Affect the Performance of Croatian Banks

In this paper, the authors tried to examine whether and to what extent board structure influences bank performance. Although this issue has occupied scholars and researchers over the years, most of them relate to the US banking market or other developed countries and, to a much lesser extent, to the European markets. With the aim of fulfilling this gap, we decided to find out evidence on the aforementioned relationship in the banking sector in Croatia. Specifically, our analysis was conducted on a sample of Croatian banks and savings banks in the 2002-2013 period. Using four measures of board structure such as gender of the president of the management board, management board female members, supervisory board size and supervisory board female members and employing Arellano-Bover/Blundell-Bond estimator, the research results indicate that the supervisory board size and the participation of women as president of the management board do not make an influence on bank performance. However, the growth of the proportion of women in both management and supervisory boards negatively affects bank performance.
Leather inspection by oriented texture analysis with a morphological approach

This paper deals with oriented texture analysis applied to a problem of defect detection and classification in leather inspection, for industrial application. In this paper we present results obtained using a defects detector based on oriented texture analysis, which reveals itself useful for a few classes of leather defects, such as scars or folds. These defects can be detected by using a black and white camera running over the leather patch and by classifying textures, on the basis of their gradient orientations and local coherence. Leather defects are detected by segmenting the oriented texture map of the leather surface. The orientation in every point is expressed using a normalized B-spline basis whose knots are distributed on the leather surface. The resulting erector of coefficients can be used to perform the final segmentation and localize defective areas. A morphological segmentation procedure is applied to the regularized oriented texture field in order to extract probable defective areas.
Sublingual immunotherapy in children – ready for prime time?

After a decade of controversies, high-dose sublingual immunotherapy (SLIT) has been demonstrated to be a safe and effective therapy option for adults and children with pollen. Studies have clearly shown that there is a dose-response relationship with regard to reduction of symptoms and symptomatic medication intake. Moreover, comparison of different trials indicate the fact that clinical efficacy of SLIT may depend on the duration of therapy. Therefore for both, children and adults, SLIT should only be performed with high-dose preparations providing documented efficacy for a sufficient period of time to ensure that the best benefit is achieved.
Immigrant Qualifications: Recognition and Relative Wage Outcomes

Australian society is most unusual in that it is characterized by relatively large numbers of immigrants, many of whom are ostensibly skilled workers. This empirical exercise used a data set compiled under the auspices of the Commonwealth Government. The data revealed that around 39 percent of skilled immigrants chose to subject their overseas qualifications to local assessment and, of these, 42 percent were recognized as being equivalent to their Australian counterpart. The econometric wage estimations reveal that immigrants from non-English-speaking countries, as a whole, received low increments as a consequence of overseas qualifications compared to those having Australian qualifications.
The Nursing Care of the Infant Receiving Bubble CPAP Therapy

There are increasing numbers of low birth-weight and premature infants surviving with conditions such as chronic lung disease or bronchopulmonary dysplasia due to complications of assisted mechanical ventilation and other factors. Continuous positive airway pressure (CPAP) has been used as an alternative respiratory treatment to prevent and manage lung disease in preterm infants since the 1970s. Evidence has demonstrated the usefulness of CPAP in the delivery room, as a rescue therapy, as an extubation tool, and a method for managing apnea of prematurity. Bubble CPAP is a unique, simple, inexpensive way of providing continuous positive pressure to infants. Some background and training in the setup, care, and evaluation of the infant on bubble CPAP is essential for positive outcomes.
Prevention of a First Myocardial Infarction

Coronary heart disease is the leading cause of morbidity and mortality in men and women in the Western world. We now have significant evidence that prevention of the first coronary event using lifestyle and pharmacologic therapies is paramount. Events are caused by inflamed arteries leading to rupture of atherosclerotic plaques that induce potentially occlusive thrombi. Analysis of event reduction trials has revealed that LDL‐C lowering is only one part of the therapy needed to stabilize plaque. HMG‐Co‐A‐reductase inhibitors, fibrates, and statins all have differing mechanisms of action that provide not only lipid but also inflammatory, rheologic, and co‐agulation benefits. Concentration and sizes of lipoprotein subfractions have emerged as important new tools with small dense LDL particles having more atherogenicity, which has led to an increasing use of aggressive combination therapy for prevention of first myocardial infarction. Proper use of lipid‐lowering therapies requires knowledge of drug metabolism drug‐drug interactions.
Peroxiredoxin I and II inhibit H2O2‐induced cell death in MCF‐7 cell lines

Apoptosis is known to be induced by direct oxidative damage due to oxygen‐free radicals or hydrogen peroxide or by their generation in cells by the actions of injurious agents. Together with glutathione peroxidase and catalase, peroxiredoxin (Prx) enzymes play an important role in eliminating peroxides generated during metabolism. We investigated the role of Prx enzymes during cellular response to oxidative stress. Using Prx isoforms‐specific antibodies, we investigated the presence of Prx isoforms by immunoblot analysis in cell lysates of the MCF‐7 breast cancer cell line. Treatment of MCF‐7 with hydrogen peroxide (H2O2) resulted in the dose‐dependent expressions of Prx I and II at the protein and mRNA levels. To investigate the physiologic relevance of the Prx I and II expressions induced by H2O2, we compared the survivals of MCF10A normal breast cell line and MCF‐7 breast cancer cell line following exposure to H2O2. The treatment of MCF10A with H2O2 resulted in rapid cell death, whereas MCF‐7 was resistant to H2O2. In addition, we found that Prx I and II transfection enabled MCF10A cells to resist H2O2‐induced cell death. These findings suggest that Prx I and II have important functions as inhibitors of cell death during cellular response to oxidative stress. J. Cell. Biochem. 101: 1038–1045, 2007. © 2007 Wiley‐Liss, Inc.
Integration und Analyse von Artefakten in der modellbasierten Entwicklung eingebetteter Software

Nowadays, functional and safety requirements of vehicles can hardly be met without embedded software since a pure hardware-oriented realisation would be too complex and would result a huge number of electronic control units. Hence, the vehicle’s weight would increase leading to a higher fuel consumption. During the last years, MATLAB/Simulink has become state of the art for the development of embedded software in the automotive domain. Furthermore, in order to make advantage of commonalities a software product line approach is applied. This kind of development raises new challenges in the context of complexity and evolution management of embedded software. For instance, dependencies within Simulink models as well as links among design artefacts like Simulink model and requirements document are frequently not obvious. Hence, later change requests become more and more complicated to incorporate. This thesis first presents a general concept for artefact integration and analysis in the context of embedded software development in the automotive domain. Second, the concept is realised with two implementation approaches following different paradigms. The model-based approach first parses the original artefacts into models of the Eclipse Modeling Framework (EMF) which are subsequently structurally optimised by model transformations to facilitate later analyses. This results in one EMF model per artefact, the so-called representative. The artefact integration is realised by links among the representatives’ meta models. Analyses of artefacts, which are again realised by model transformations, now operate on these representatives leading to a further EMF model representing the analysis result. The second approach integrates artefacts via a central database. To this end, the original artefacts are first transferred into Java models applying tool-specific as well as Java functionality. In the next step, these models are persisted in the database where they can be linked to each other. Analyses operate on both Java models and the database and are, hence, implemented in Java. After a detailed explanation, the suitability of the approaches for artefact integration and analysis in an industrial context is evaluated based on case studies and developers’ opinions. To this end, the run time efficiency and the scalability to huge Simulink models are investigated. Furthermore, generalisability and extensibility are discussed. Since each approach has to be adaptable to company-specific needs, the complexity of analysis implementation and the necessary background knowledge are considered as well.
Distinct Requirements of MicroRNAs in NK Cell Activation, Survival, and Function

MicroRNAs (miRNAs) are small noncoding RNAs that have recently emerged as critical regulators of gene expression within the immune system. In this study, we used mice with conditional deletion of Dicer and DiGeorge syndrome critical region 8 (Dgcr8) to dissect the roles of miRNAs in NK cell activation, survival, and function during viral infection. We developed a system for deletion of either Dicer or Dgcr8 in peripheral NK cells via drug-induced Cre activity. We found that Dicer- and Dgcr8-deficient NK cells were significantly impaired in survival and turnover, and had impaired function of the ITAM-containing activating NK cell receptors. We further demonstrated that both Dicer- and Dgcr8-dependent pathways were indispensable for the expansion of Ly49H+ NK cells during mouse cytomegalovirus infection. Our data indicate similar phenotypes for Dicer- and Dgcr8-deficient NK cells, which strongly suggest that these processes are regulated by miRNAs. Thus, our findings indicate a critical role for miRNAs in controlling NK cell homeostasis and effector function, with implications for miRNAs regulating diverse aspects of NK cell biology.
A 120-GHz Electrical Interferometer for Contactless Permittivity Measurements With Direct Digital Read-Out

This work describes an electrical interferometer for contactless permittivity measurements working at 120 GHz. It was fabricated in a 130 nm SiGe process featuring an ft and fmax of 240 and 330 GHz. The on-chip system contains a 120 GHz VCO with a tuning range of 7 GHz featuring a divide-by-64 circuit to enable external PLL operation. The subsequent buffer provides 7 dBm of output power at 120 GHz. Additionally, the IC contains high-precision and high-resolution phase shifters based on a slow-wave transmission line approach with digital control for direct readout ability. A 120 GHz LNA with 17 dB gain and a power detector to provide DC output signals were realized on chip. It enables sample emulation capability by phase shift inducement in the measurement as well as a reference transmission line. In terms of phase detection, the system shows a sensitivity of 907.36 MHz/°.
Bifurcation in PWM converter-based systems with wireless communication-based current controller

This paper discusses the stability of current control for pulse-width modulated (PWM) voltage source converters (VSCs) subject to communication delay. The converters can be used properly as interface of controllable distributed energy resources (DERs) or for the active integration of converter-interfaced loads (CILs). The stability analysis is based on the identification of oscillatory modes by the bifurcation analysis. The bifurcation map indicates the non-linear impact of the communication delay on the output current of a three phase PWM inverter. The aim of the paper is to find limit delay for which the stability criteria of the controller are still satisfied. This limit delay allows for maximal flexibility for the communication system designer and leads to better resource allocation in case of channel distortion, limited bandwidth, etc in the wireless communication system.
Relationship between DNA Barcoding and Chemical Classification of Salvia Medicinal Herbs

Objective To make the identification of medicinal herbs in Salvia L. quickly and accurately. Methods In this work, DNA barcoding and chemical fingerprint were compared for the identification of herbs in Salvia L. First, the nucleotide sequences of the internal transcribed spacer region two amplified from 48 medicinal plants in Salvia L. , and three other groups of medicinal plants in Lamiaceae were sequenced. A molecular phylogeny was constructed using the minimum evolution and maximum parsimony methods according to their sequence diversity. Second, the water-solution bioactive components and lipid soluble components were tested by HPLC. Then a chemical phylogeny was built using HPLC fingerprint data. Comparing the molecular and chemical phylogenetic trees revealed many similarities. Results DNA barcoding was sequencing based and could therefore provide more accurate results within a shorter time especially in large-scale studies. Conclusion The results show that ITS2 region is a novel DNA barcode for the authentication of the species in Salvia L. This is the first work to show the relationship between DNA barcoding and chemical components.
The analysis of chromatin organisation allows selection of mouse antral oocytes competent for development to blastocyst

Mouse antral oocytes can be classified in two different types termed SN or NSN oocytes, depending on the presence or absence, respectively, of a ring of Hoechst 33342-positive chromatin surrounding the nucleolus. The aim of the present study was to test the developmental competence to blastocyst of the two types of oocytes. Here we show that following isolation, classification and culture of cumulus-free antral oocytes, 14.7% and 74.5% of NSN and SN oocytes, respectively, reached the metaphase II stage. When fertilised and further cultured none of the metaphase II NSN oocytes developed beyond the 2-cell stage whilst 47.4% of the metaphase II SN oocytes reached the 4-cell stage and 18.4% developed to blastocyst. The findings reported in this paper may contribute to improved procedures of female gamete selection for in vitro fertilisation of humans and farm animals. Furthermore, the selection of oocytes with better developmental potential may be of interest for studies on nuclear/cytoplasm interaction, particularly in nuclear-transfer experiments.