Miracle-dz/UniFAR-FTUs huggingface dataset:
Thermoset Polymer Reinforced with Silica Micro and Nanoparticles

Fiber-reinforced composites (FRCs) have been used to replace conventional materials in a wide range of applications in transportation and civil engineering. The dispersion of nanoparticles and microparticles into epoxy matrix phase has been widely investigated to enhance the mechanical properties of hybrid FRCs. The nanoparticles generate large attractive forces among themselves, providing a significant tendency to agglomerate. A chemical treatment based on diallyldimethylammonium chloride (PDDA) was evaluated to disperse the silica nanoparticles within the epoxy polymer. A microstructural analysis was conducted to better assess the results. Experimental analysis was carried out based on the analysis of variance (ANOVA) and Tuckey test in order to verify the effect of PDDA treatment, silica particle size (micro and nano), and silica particle inclusion (1, 2, and 3.5 wt.%) on the mechanical properties of epoxy polymer commonly used as matrix phase in FRCs. The PDDA treatment was able to disperse the silica nanoparticles. The incorporation of 1 wt. % of silica micro or 1 and 2 wt. % of nanoparticles slightly improved the tensile strength and modulus of the epoxy polymer.
Functional Characterization of Waterlogging and Heat Stresses Tolerance Gene Pyruvate decarboxylase 2 from Actinidia deliciosa

A previous report showed that both Pyruvate decarboxylase (PDC) genes were significantly upregulated in kiwifruit after waterlogging treatment using Illumina sequencing technology, and that the kiwifruit AdPDC1 gene was required during waterlogging, but might not be required during other environmental stresses. Here, the function of another PDC gene, named AdPDC2, was analyzed. The expression of the AdPDC2 gene was determined using qRT-PCR, and the results showed that the expression levels of AdPDC2 in the reproductive organs were much higher than those in the nutritive organs. Waterlogging, NaCl, and heat could induce the expression of AdPDC2. Overexpression of kiwifruit AdPDC2 in transgenic Arabidopsis enhanced resistance to waterlogging and heat stresses in five-week-old seedlings, but could not enhance resistance to NaCl and mannitol stresses at the seed germination stage and in early seedlings. These results suggested that the kiwifruit AdPDC2 gene may play an important role in waterlogging resistance and heat stresses in kiwifruit.
Cardiovascular responses induced by Catalase Inhibitior into the Fourth Cerebral Ventricle is changed in Wistar rats exposed to sidestream cigarette smoke.

OBJECTIVES This experimental study aimed to evaluate the effects of central catalase inhibition on cardiovascular responses in rats exposed to sidestream cigarette smoke (SSCS) for 3 weeks. METHODOLOGY A total of 20 males Wistar rats (320-370g) were implanted with a stainless steel guide cannula into the fourth cerebral ventricle (4(th)V). Femoral artery and vein were cannulated for mean arterial pressure (MAP) and heart rate (HR) measurement and drug infusion, respectively. Rats were exposed to SSCS for three weeks, 180 minutes per day, 5 days/week [carbon monoxide (CO): 100-300 ppm)]. Baroreflex was tested with one pressor dose of phenylephrine (PHE, 8 μg/kg, bolus) and one depressor dose of sodium nitroprusside (SNP, 50 μg/kg, bolus). Cardiovascular responses were evaluated before and 15 minutes after 3-amino-1, 2, 4-triazole (ATZ, catalase inhibitor, 0.001g/100μL) injection into the 4(th) V. RESULTS Vehicle treatment into the 4(th) V did not change cardiovascular responses. Central catalase inhibition increased tachycardic peak, attenuated bradycardic peak and reduced HR range at 15 minutes, increased MAP at 5, 15 and 30 min and increased HR at 5 and 15 min. In rats exposed to SSCS, central ATZ increased basal MAP after 5 min and increased HR at 5, 15 and 30 minutes, respectively, and attenuated bradycardic peak at 15 minutes. CONCLUSION This study suggests that brain oxidative stress caused by SSCS influences autonomic regulation of the cardiovascular system.
Polymorphisms in Th1/Th2 Cytokine Genes, Hormone Replacement Therapy, and Risk of Non-Hodgkin Lymphoma

We conducted a population-based case–control study in Connecticut women to test the hypothesis that genetic variations in Th1 and Th2 cytokine genes modify the relationship between hormone replacement therapy (HRT) and risk of non-Hodgkin lymphoma (NHL). Compared to women without a history of HRT use, women with a history of HRT use had a significantly decreased risk of NHL if they carried IFNGR2 (rs1059293) CT/TT genotypes (OR = 0.5, 95%CI: 0.3–0.9), IL13 (rs20541) GG genotype (OR = 0.6, 95%CI: 0.4–0.9), and IL13 (rs1295686) CC genotype (OR = 0.6, 95%CI: 0.4–0.8), but not among women who carried IFNGR2 CC, IL13 AG/AA, and IL13CT/TT genotypes. A similar pattern was also observed for B-cell lymphoma but not for T-cell lymphoma. A statistically significant interaction was observed for IFNGR2 (rs1059293 Pfor interaction = 0.024), IL13(rs20541 Pfor interaction = 0.005), IL13 (rs1295686 Pfor interaction = 0.008), and IL15RA (rs2296135 Pfor interaction = 0.049) for NHL overall; IL13 (rs20541 Pfor interaction = 0.0009), IL13(rs1295686 Pfor interaction = 0.0002), and IL15RA (rs2296135 Pfor interaction = 0.041) for B-cell lymphoma. The results suggest that common genetic variation in Th1/Th2 pathway genes may modify the association between HRT and NHL risk.
Experimental study on impact tensile property of glass fiber

The tensile properties of E-glass, which is the most popular reinforcement fiber in composite materials, were determined from the experimental results of fiber bundle testing under a high strain rate. The tests were performed by using two types of experimental methods. One is the tension-type split Hopkinson bar system and the other is the universal high-speed tensile-testing machine. In the results, it was demonstrated that the tensile strength and fracture strain of E-glass fiber increased with the strain rate. The absorbed strain energy, therefore, significantly increased. It was also shown that the strain rate dependency of E-glass fiber tensile strength was strongly affected by fiber diameter. The smaller diameter of E-glass fiber has the stronger strain rate dependency. Finally, the impact tensile strengths of high-strength glass and carbon fibers were investigated. It was confirmed that the tensile strength of the high-strength glass fiber also increased with the strain rate, but the tensile properties of carbon fiber were almost independent of the strain rate.
The Textual Idea and its Relationship to discourse structure

The textual idea could be characterized through a series of either detailing the current form of idea or continuing a previous form of it. Every element of the series has associated a span of the given text that carries it. If we are to relate different spans of text according to relationship between corresponding elements of the series, we will obtain a possible representation of discourse structure. In this paper we take a set of texts and represent their structure in the above manner. The purpose is to give researchers the possibility to asset our manner to represent discourse structure.
RUTH AYLETT AND THEY BOTH LIVED HAPPILY EVER AFTER ? Digital stories and learning

In this paper we consider the role of story in digital technology enhanced learning and the issues involved in constructing digital narrative learning environments. We will see that story has played an important role in education for a very long time, well pre-dating the use of digital technologies, and can be closely related to a number of theoretical approaches to learning. However story has recently become a much more significant topic for research, not only in education and digital technology, but also in other fields, such as knowledge management, and we examine why it has become such a central concern. The paper then looks at the existing use of story in fielded educational applications, and questions how far it has actually been used as an essential mechanism – producing a narrative learning environment rather than merely as motivational support. The relationship between story and computer games is an important issue here. We argue that the interactivity of digital media raises fundamental problems for the use of story that are still challenging researchers, and look at the various approaches to dealing with these problems, citing a number of example systems. Finally, we discuss the direction in which the technology is moving – what it offers now and what it may offer in the near future, and what technology support is currently available for creating digital narrative learning environments.
How much cost reduction justifies the adoption of monolithic 3D ICs at 7nm node?

In this paper we study power, performance, and cost (PPC) tradeoffs for 2-tier, gate-level, full-chip GDS monolithic 3D ICs (M3D) built using a foundry-grade 7nm bulk FinFET technology. We first develop highly-accurate wafer and die cost models for 2D and M3D to study PPC tradeoffs. In our study, both 2D and M3D designs are optimized in terms of the number of BEOL metal layers used for routing to obtain the best possible PPC values. We develop a new CAD methodology for 2-tier gate-level M3D, named Projected 2D Flow, that allows us to accurately compare RC parasitics of equivalent nets in both 2D and M3D designs. Our experiments based on two different circuit types (BEOL-dominant vs. FEOL-dominant) confirm that M3D designs indeed offer a significant footprint saving. However, to our surprise, the PPC quality of M3D turns out to be worse than that of 2D by 34% due to the high wafer cost of M3D. Our study also reveals that M3D wafer yield should be as high as 90% of 2D wafer yield, and the M3D device manufacturing cost should be less than 33% of that of 2D to justify the adoption of M3D technology at the 7nm era. Lastly, and counter-intuitively, our study shows that FEOL-dominant circuit shows more PPC benefits from M3D technology than BEOL-dominant circuit.
Early assessment of acute coronary syndromes in the emergency department: the potential diagnostic value of circulating microRNAs

Previous studies investigating the role of circulating microRNAs in acute coronary syndrome (ACS) were based on small patient numbers, performed no comparison with established markers of cardiac injury and did not have appropriate controls. We determined the potential diagnostic value of circulating microRNAs as novel early biomarkers in 332 suspected ACS patients on presentation to the emergency department (ED) in a prospective single‐centre study including cardiac miRNAs (miR‐1, ‐208a and ‐499), miR‐21 and miR‐146a. Levels of all miRs studied were significantly increased in 106 patients diagnosed with ACS, even in patients with initially negative high‐sensitive (hs) troponin or symptom onset <3 h. MiR‐1, miR‐499 and miR‐21 significantly increased the diagnostic value in all suspected ACS patients when added to hs‐troponin T (AUC 0.90). These three miRs were strong predictors of ACS independent of clinical co‐variates including patient history and cardiovascular risk factors. Interestingly, the combination of these three miRs resulted in a significantly higher AUC of 0.94 than hs‐troponin T (0.89). Circulating microRNAs hold great potential as novel early biomarkers for the management of suspected ACS patients.
Preparation of Phi29 DNA Polymerase Free of Amplifiable DNA Using Ethidium Monoazide, an Ultraviolet-Free Light-Emitting Diode Lamp and Trehalose

We previously reported that multiply-primed rolling circle amplification (MRPCA) using modified random RNA primers can amplify tiny amounts of circular DNA without producing any byproducts. However, contaminating DNA in recombinant Phi29 DNA polymerase adversely affects the outcome of MPRCA, especially for negative controls such as non-template controls. The amplified DNA in negative control casts doubt on the result of DNA amplification. Since Phi29 DNA polymerase has high affinity for both single-strand and double-stranded DNA, some amount of host DNA will always remain in the recombinant polymerase. Here we describe a procedure for preparing Phi29 DNA polymerase which is essentially free of amplifiable DNA. This procedure is realized by a combination of host DNA removal using appropriate salt concentrations, inactivation of amplifiable DNA using ethidium monoazide, and irradiation with visible light from a light-emitting diode lamp. Any remaining DNA, which likely exists as oligonucleotides captured by the Phi29 DNA polymerase, is degraded by the 3′-5′ exonuclease activity of the polymerase itself in the presence of trehalose, used as an anti-aggregation reagent. Phi29 DNA polymerase purified by this procedure has little amplifiable DNA, resulting in reproducible amplification of at least ten copies of plasmid DNA without any byproducts and reducing reaction volume. This procedure could aid the amplification of tiny amounts DNA, thereby providing clear evidence of contamination from laboratory environments, tools and reagents.
Optimizing airflow reversals for kiln drying of softwood timber by applying mathematical models

After experimental validation of a kiln-wide drying model, a single board drying model and a stress model for kiln drying of softwood timber, these models are integrated and used to investigate benefits of airflow reversals in smoothing moisture content distribution and in reducing drying stresses for commercial kiln drying. In the current study, a high temperature drying schedule (DB/WB of 120/70°C and air velocity of 5 m/s) was simulated and 5 strategies for airflow reversal were evaluated. These strategies are: airflow reversal every hour; airflow reversal every 2 hours; airflow reversal every 3 hours and airflow reversal after 2 and 10 hours of drying. The results are compared to ‘Control’ in which airflow is unidirectional (no reversal). It has been found that, for the moisture content distribution, the first reversal is critical and frequencies of subsequent flow reversals can be varied depending on the drying temperature used. However, more frequent airflow reversal has benefits in reducing drying stresses. These findings are consistent with observations in commercial kiln drying of softwood lumber.
Ground-Based Gamma-Ray Detection of High Energy Galactic Sources: An Update

I review the present status of ground-based gamma-ray astronomy, concentrating on the population of galactic TeV sources. A number of new telescope systems are now being completed, and promise to yield exciting new discoveries, expanding rapidly the number of sources. The TeV galactic sources today include a number of plerions, shell-type SNR, an X-ray binary, and also one unidentified candidate. Their present status, and our understanding of their TeV gamma-ray emission processes are summarised and some motivation driving development of the field is outlined.
Prosody-Driven Head-Gesture Animation

We present a new framework for joint analysis of head gesture and speech prosody patterns of a speaker towards automatic realistic synthesis of head gestures from speech prosody. The proposed two-stage analysis aims to "learn" both elementary prosody and head gesture patterns for a particular speaker, as well as the correlations between these head gesture and prosody patterns from a training video sequence. The resulting audio-visual mapping model is then employed to synthesize natural head gestures from arbitrary input test speech given a head model for the speaker. Objective and subjective evaluations indicate that the proposed synthesis by analysis scheme provides natural looking head gestures for the speaker with any input test speech.
Changes in Neurocognitive Function in Patients With Schizophrenia After Starting or Switching to Amisulpride in Comparison With the Normal Controls

Abstract We examined short- and long-term changes in neurocognitive functions in patients with schizophrenia who were either started or switched to amisulpride in comparison with the normal controls. Fifty-seven patients treated with amisulpride and 60 normal controls completed a comprehensive neurocognitive function test battery at the baseline, the 8-week, and the 1-year follow-up. We conducted and compared the results of both intention-to-treat (ITT) and per-protocol (PP) analyses to account for the follow-up loss. Three general results obtained were as follows: (1) the degree of the improvements in neurocognitive function was comparable to those of other second-generation antipsychotics in both ITT and PP analysis; (2) in light of the relative effect size, the composite effect size and the effect size in most measures in both ITT and PP analyses were smaller for the patient group than those of the control group, signifying that improvement in performance may be largely attributable to practice effects; and (3) nonetheless, there were evidences of both short- and long-term improvements in some cognitive tasks, such as in the Korean-Wechsler Adult Intelligence Scale vocabulary subtest and the Trail Making Test, that may not be accounted by practice effect. These results suggest the need to include a healthy control group to validate the medication effect of cognitive improvements in patients with schizophrenia and to consider practice effect in interpreting the results of repeated administration of neurocognitive function tests.
Ash from Oil-Palm Waste as a Concrete Material

The palm‐oil industry produces large amounts of solid wastes. Shell and fiber wastes are used extensively as fuel for steam production in palm‐oil mills. After combustion, a large quantity of ash is produced and creates problems of disposal. The feasibility of using the shell and fiber ash as a construction material is studied. The material differs from PFA from coal‐fired power plants in that it has a higher content of residual organic, a higher alkali content, is coarser. The experimental results indicate that no significant effects of ash addition on the segregation, shrinkage, water absorption, density, and soundness of cement. The workability of concrete blended with the shell and fiber ash is good, and setting times are well within the requirements of both American and British standards. The shell and fiber ash is only weakly pozzolanic, the decrease in compressive strength of concrete is almost proportional to the amount of ash in the blended cement, except when only 10% ash is used. The results sh.
Coated Si microwire array solar cells for better light trapping

We investigated optical properties of planar Si wafers and Si microwire (MW) arrays with and without ZnO thin films using the finite-difference time-domain (FDTD) method. Reflectance of the MW array (diameter: 4 μm and period: 12 μm) was smaller than that of the planar wafer in the wavelength range from 400 to 1100 nm, which could be originated from antireflection effects due to low optical density and guided-mode-assisted field enhancement. The reflectance of ZnO (thickness: 50 and 80 nm)-coated MW array was drastically reduced compared with the bare array but somewhat larger than that of the coated planar wafer. This could be attributed to less-confined guided modes in the wires, which was supported by the field distribution simulation results. Our results provide some insights into possible roles of transparent conducting layers on MW arrays for photovoltaic applications.
Deformation and Failure of Open‐Cell Foams Made of TRIP‐Steel‐ZrO2‐Composite Materials: Experimental Observations Versus Numerical Simulations

The aim of the study is to clarify how far it is possible to describe the mechanical behavior of novel TRIP‐Steel/Mg‐PSZ composite open‐cell foam structures using beam networks generated from random tessellations. Conventional compression tests were performed with various foam samples. Furthermore, the deformation of open‐cell composite foams was observed as well by X‐ray computed tomography (XCT). Up to a compressive strain of 20% different stages of deformation could be observed. Respective bulk samples were manufactured by powder metallurgy and tested in order to determine the mechanical properties of the bulk material. Numerical simulations were employed based on the suitable modeling of foams exposed to mechanical loading. The predictions of the simulation are compared with the results of the deformation experiments.
Bootstrap Learning of Heuristic Functions

search algorithms such as IDA* or heuristic-search planners. Our method aims to generate a strong heuristic from a given weak heuristic h0 through bootstrapping. The "easy" problem instances that can be solved using h0 provide training examples for a learning algorithm that produces a heuristic h1 that is expected to be stronger than h0. If h0 is too weak to solve any of the given instances we use a random walk technique to create a sequence of successively more difficult instances starting with ones that are solvable by h0. The bootstrap process is then repeated using hi in lieu of hi–1 until a sufficiently strong heuristic is produced. We test our method on the 15- and 24-sliding tile puzzles, the 17- and 24-pancake puzzles, and the 15- and 20-blocks world. In every case our method produces a heuristic that allows IDA* to solve randomly generated problem instances extremely quickly with solutions very close to optimal.
Continuous topology simplification of planar vector fields

Vector fields can present complex structural behavior, especially in turbulent computational fluid dynamics. The topological analysis of these data sets reduces the information, but one is usually still left with too many details for interpretation. In this paper, we present a simplification approach that removes pairs of critical points from the data set, based on relevance measures. In contrast to earlier methods, no grid changes are necessary, since the whole method uses small local changes of the vector values defining the vector field. An interpretation in terms of bifurcations underlines the continuous, natural flavor of the algorithm.
Keratinocytes as Depository of Ammonium-Inducible Glutamine Synthetase: Age- and Anatomy-Dependent Distribution in Human and Rat Skin

In inner organs, glutamine contributes to proliferation, detoxification and establishment of a mechanical barrier, i.e., functions essential for skin, as well. However, the age-dependent and regional peculiarities of distribution of glutamine synthetase (GS), an enzyme responsible for generation of glutamine, and factors regulating its enzymatic activity in mammalian skin remain undisclosed. To explore this, GS localization was investigated using immunohistochemistry and double-labeling of young and adult human and rat skin sections as well as skin cells in culture. In human and rat skin GS was almost completely co-localized with astrocyte-specific proteins (e.g. GFAP). While GS staining was pronounced in all layers of the epidermis of young human skin, staining was reduced and more differentiated among different layers with age. In stratum basale and in stratum spinosum GS was co-localized with the adherens junction component ß-catenin. Inhibition of, glycogen synthase kinase 3β in cultured keratinocytes and HaCaT cells, however, did not support a direct role of ß-catenin in regulation of GS. Enzymatic and reverse transcriptase polymerase chain reaction studies revealed an unusual mode of regulation of this enzyme in keratinocytes, i.e., GS activity, but not expression, was enhanced about 8–10 fold when the cells were exposed to ammonium ions. Prominent posttranscriptional up-regulation of GS activity in keratinocytes by ammonium ions in conjunction with widespread distribution of GS immunoreactivity throughout the epidermis allows considering the skin as a large reservoir of latent GS. Such a depository of glutamine-generating enzyme seems essential for continuous renewal of epidermal permeability barrier and during pathological processes accompanied by hyperammonemia.