Miracle-dz/UniFAR-FTUs huggingface dataset:
Evaluating First Year Agriculture Teachers’ Use of Reflection

Reflection is a useful tool which improves teaching approaches; however, many first-year teachers do not appear to reflect upon their instructional plans (McAlpine & Weston, 2000). Prior research has indicated preservice teachers are not utilizing the acquired reflective approaches learned throughout the teacher preparation program (Hatton & Smith, 1995; Kagan & Tippins, 1992; Reynolds, 1993). It is believed teachers fail to implement reflective practice in their professional practice because they have not acquired the pedagogical knowledge to effectively reflect (McAlpine & Weston, 2000). The primary purpose of this study was to determine if beginning agricultural education teachers employed a systematic approach of reflection, determine what components of the teacher preparation program aided in learning, how to reflect, and to examine first-year teachers’ gratification with the reflective approaches learned from Iowa State University agricultural education teacher preparation program. The study drew on the theoretical framework of John Dewey and Donald Schon in support of reflection throughout an educator’s professional teaching career. This qualitative study consisted of phone interviews with six first-year secondary teachers who graduated from the teacher preparation program. All first-year teachers employed a systematic reflection approach and preferred the following approaches to reflection: written reflection, verbal reflection, or through internal dialogue. First-year teachers indicated they learned how to reflect from student teaching, the tuning protocol process, and in core classes. However, they indicated preservice teachers need more exposure to reflection during their student teaching experience and throughout coursework.
Serum measurement of thymus and activation‐regulated chemokine/CCL17 in children with atopic dermatitis: elevated normal levels in infancy and age‐specific analysis in atopic dermatitis

Elevated blood levels of thymus and activation‐regulated chemokine (TARC)/CCL17 have been observed in atopic dermatitis (AD) and may serve as a new biomarker for AD. However, the normal levels, especially in children, have not been well determined. We sought to establish an efficient enzyme‐linked immunosorbent assay (ELISA) with a wide range of detection that would be suitable for measurement of serum TARC/CCL17 and to determine the normal ranges of this chemokine in different age groups and its diagnostic usefulness for AD. A sensitive specific ELISA for TARC/CCL17, which we previously reported, was modified to accommodate the wide range of TARC/CCL17 values often found in sera. Twenty‐seven children with AD under 6 yr of age and 25 age‐matched normal non‐atopic controls, and 18 patients with AD and 27 controls who were 6 yr and older were enrolled. The severity of AD was evaluated using the SCORAD index. The serum levels of TARC/CCL17 were measured with the ELISA, and the serum levels of IP‐10/CXCL10 were also measured. With the novel ELISA system, the assayable range of TARC/CCL17 was 14–8000 pg/ml, and the coefficient of variation at various concentrations ranged from 2.3% to 5.0%. The serum levels of TARC/CCL17 in normal individuals were significantly higher in young children, especially in the age group of 0–1 yr. The cut‐off values of TARC/CCL17 for the diagnosis of AD were 1431 pg/ml for 0–1 yr group, 803 pg/ml for 2–5 yr group and 510 pg/ml for the 6 yr and older group, with high sensitivity and specificity of 0.83 and 0.93, 0.83 and 0.92, 0.85 and 0.96, respectively. The magnitude of the decrease in the SCORAD index after treatment with topical steroids correlated significantly with the decrease in serum TARC/CCL17. There was no difference in the serum levels of IP‐10/CXCL10 between AD and the controls. The TARC/CCL17:IP‐10/CXCL10 ratio tended to be higher in the control children aged 0–1 yr than in those aged 2–5 yr. The serum level of TARC/CCL17 reflects the severity and therapeutic response in AD. The high normal levels in infants should be taken into account when assaying TARC/CCL17.
Spillover Effect of Global Financial Cycle To Asset Markets in Asean-5 Countries: A Structural VAR Approach

An upsurge and volatility of capital flows to Emerging Asian Economies indicated that there is the potential effect of global financial cycle to emerging market. It provides an overview of investor risk aversion in short term investment after financial crisis 2008. Global financial cycle could have a significant impact to asset prices, including equity prices and property prices. Rey (2015) has triggered an interesting discussion about global financial cycle. She found that there was a global financial cycle in capital flows, asset prices and credit growth. This cycle was co ‐ moves with the VIX, a measure of uncertainty and risk aversion of the markets. Therefore, this study attempts to analyze empirically global financial cycle shocks, measured by the VIX, on equity prices and property prices in ASEAN-5, namely Indonesia, Malaysia, Singapore, Thailand and Philippines. We estimate quarterly frequency data from Q1 1990 to Q2 2016 with Structural Vector Autoregressive (SVAR) approach. The result of this study showed that global financial cycle has a negative significant impact on the ASEAN-5 asset markets, in spite of the response of shock differs by country and size. This result is consistent with ASEAN-5 as small open economies that remain vulnerable to the global factor. This study contributes to the literature in several ways. First, we identify not only cyclical expansions or contraction in asset markets but also the impact of global financial cycle to asset markets in ASEAN-5 countries. Second, we investigate whether there are heterogeneous responses of ASEAN-5 countries to global financial cycle shocks. Third, we also identify the pattern of cycle in ASEAN-5 countries . J EL Classification: F30, F37, F42 Keywords: ASEAN, Asset Markets, Global Financial Cycle, SVAR
Genomic organization and refined mapping of the human nuclear corepressor 2 (NCOR2)/ silencing mediator of retinoid and thyroid hormone receptor (SMRT) gene on chromosome 12q24.3

The human nuclear co-repressor 2 (N-CoR2) gene (NCOR2, previously called silencing mediator for retinoid and thyroid hormone receptor SMRT) is recruited to nuclear and non-nuclear receptors in a large repressing complex containing also N-CoR1, mSin3 and HDACs. This large complex represses transcription in absence of ligand. Herein we report the high- resolution and refined mapping of NCOR2 at the boundary of sub-bands 12q24.23 and 12q24.31, and its intron/exon structure. The gene contains 45 exons. This information should allow further study of potential NCOR2 genomic alteration in some subsets of malignancies.
Does recall of preinjury disability change over time?

Background Pre-injury disability must be determined when assessing whether treatment programs return people to pre-injury status, however there is little empirical evidence to support recommendations that this be done as soon as possible after injury to prevent recall bias. Objectives To determine disagreement between recall of pre-injury disability at different time points post-injury and bias towards under- or overestimating pre-injury disability. Methods Self-reported pre-injury global disability was assessed within days, 6 months and 12 months post-injury in patients admitted to two level 1 adult trauma centres. Kappa statistics and multiple logistic regression models identified predictors of disagreement between time-points. Results Pre-injury disability was measured at all time-points in 801 patients. Pre-injury disability at baseline was rated as none, mild, moderate, marked and severe in 80%, 12%, 5.1%, 1.9% and 1.0% respectively. Absolute agreement between baseline and 6 and 12 months respectively, was 79% and 80%. Corresponding kappa values (95% confidence intervals) were 0.33 (0.26−0.40) and 0.32 (0−25−0.38). Patients over 65 years or not completing high school were more likely to report less pre-injury disability at 6 and 12 months than at baseline with adjusted odds ratios (95% confidence intervals) for these groups being 8.24 (4.32−15.72) and 1.93 (1.03−3.64) respectively. Conclusions There was little evidence of recall bias in an adult trauma population if self-reported global pre-injury disability was assessed 6 months post-injury. The recall of pre-injury disability up to 6 months post-injury can be used to determine return to pre-injury status, if assessment is not feasible shortly after injury.
Noninvasive imaging of the foveal avascular zone with high-speed, phase-variance optical coherence tomography.

PURPOSE To demonstrate the application of phase-variance optical coherence tomography (pvOCT) for contrast agent-free in vivo imaging of volumetric retinal microcirculation in the human foveal region and for extraction of foveal avascular zone dimensions. METHODS A custom-built, high-speed Fourier-domain OCT retinal imaging system was used to image retinas of two healthy subjects and eight diabetic patients. Through the acquisition of multiple B-scans for each scan location, phase differences between consecutive scans were extracted and used for phase-variance contrast, identifying motion signals from within blood vessels and capillaries. The en face projection view of the inner retinal layers segmented out from volumetric pvOCT data sets allowed visualization of a perfusion network with the foveal avascular zone (FAZ). In addition, the authors presented 2D retinal perfusion maps with pseudo color-coded depth positions of capillaries. RESULTS Retinal vascular imaging with pvOCT provides accurate measurements of the FAZ area and its morphology and a volumetric perfusion map of microcapillaries. In this study using two images from each fundus fluorescein angiography (FA) and pvOCT, the measured average areas of the FAZ from two healthy subjects were below 0.22 mm(2), and each of eight diabetic patients had an enlarged FAZ area, larger than 0.22 mm(2). Moreover, the FAZ areas demonstrated a significant correlation (r = 0.91) between measurements from FA and pvOCT. CONCLUSIONS The high-speed pvOCT allows contrast agent-free visualization of capillary networks in the human foveal region that is analogous to fundus FA imaging. This could allow for noninvasive diagnosis and progression monitoring of diabetic retinopathy in clinical settings.
New ICA criteria for the diagnosis of acute kidney injury in cirrhotic patients: can we use an imputed value of serum creatinine?

The new International Club of Ascites diagnostic criteria to diagnose acute kidney injury at hospital admission suggests the possibility of using a presumed baseline serum creatinine, defined as the last of at least two stable creatinine values during the last 3 months. Nevertheless, the possibility of the lack of such a value still remains. In these patients, the KDIGO criteria suggest to use an inverse application of MDRD equation assuming that baseline glomerular filtration rate is 75 ml/min per 1.73 m2 (imputed baseline creatinine). We tested the accuracy of this approach to detect acute kidney injury at admission in patients with decompensated cirrhosis and creatinine <1.5 mg/dl.
Golgi Phosphoprotein 3 Triggers Signal-mediated Incorporation of Glycosyltransferases into Coatomer-coated (COPI) Vesicles

Background: How Golgi phosphoprotein 3 (GOLPH3) regulates Golgi localization of glycosyltransferases in mammalian cells is poorly understood. Results: GOLPH3 mediates incorporation of glycosyltransferases into coatomer-coated vesicles. Conclusion: GOLPH3 regulates localization of glycolsyltransferases by working as a coatomer adaptor. Significance: This study provides further insight into the molecular mechanism underlying regulation of glycosyltransferases localization by GOLPH3. Newly synthesized membrane and secreted proteins undergo a series of posttranslational modifications in the Golgi apparatus, including attachment of carbohydrate moieties. The final structure of so-formed glycans is determined by the order of execution of the different glycosylation steps, which seems intimately related to the spatial distribution of glycosyltransferases and glycosyl hydrolases within the Golgi apparatus. How cells achieve an accurate localization of these enzymes is not completely understood but might involve dynamic processes such as coatomer-coated (COPI) vesicle-mediated trafficking. In yeast, this transport is likely to be regulated by vacuolar protein sorting 74 (Vps74p), a peripheral Golgi protein able to interact with COPI coat as well as with a binding motif present in the cytosolic tails of some mannosyltransferases. Recently, Golgi phosphoprotein 3 (GOLPH3), the mammalian homolog of Vps74, has been shown to control the Golgi localization of core 2 N-acetylglucosamine-transferase 1. Here, we highlight a role of GOLPH3 in the spatial localization of α-2,6-sialyltransferase 1. We show, for the first time, that GOLPH3 supports incorporation of both core 2 N-acetylglucosamine-transferase 1 and α-2,6-sialyltransferase 1 into COPI vesicles. Depletion of GOLPH3 altered the subcellular localization of these enzymes. In contrast, galactosyltransferase, an enzyme that does not interact with GOLPH3, was neither incorporated into COPI vesicles nor was dependent on GOLPH3 for proper localization.
Research progress on millimeter wave transmitarray in SKLMMW

Inspired by conventional lens antennas, the flat transmitarray has been proposed in the last decades, combining with the concept of phased arrays, to carry forward the large aperture antennas for high-gain applications with advantages of low profile, easy fabrication, low cost, and wide scanning angles, etc. The air feed scheme of the transmitarray contributes to the result that a lower loss can be achieved than that of antenna arrays with complicated feeding networks, which is very suitable for millimeter-wave (mmW) and sub-millimeter-wave (smmW) applications. This paper briefly reviews the research progress on mmW transmitarrays in State Key Lab. of Millimeter Waves (SKLMMW), Southeast University, and several prototypes operating in 30-330 GHz are presented.
Design of high-performance pedestrian and vehicle detection circuit using Haar-like features

This paper describes the design of high-performance pedestrian and vehicle detection circuit using Haar-like features for intelligent vehicle application. The proposed circuit uses a sliding window for every image frame in order to extract Haar-like features and to detect pedestrians and vehicles. A total of 200 Haar-like features per sliding window are extracted from Haar-like feature extraction circuit and the extracted features are provided to AdaBoost classifier circuit. In order to increase the processing speed, the proposed circuit adopts the parallel architecture and it can process two sliding windows at the same time. We described the proposed high-performance pedestrian and vehicle detection circuit using Verilog HDL and synthesized the gate-level circuit using 130nm standard cell library. The synthesized circuit consists of 1,388,260 gates and its maximum operating frequency is 203MHz. Since the proposed circuit processes about 47.8 640×480 image frames per second, it can be used to provide the real-time pedestrian and vehicles detection for intelligent vehicle application.
Road Estimation and Fuel Optimal Control of an Off-Road Vehicle

This paper explores the possibility to use optimal control to establish a Pareto front of fuel consumption vs cycle time for a transport mission with an articulated hauler. The Pareto front can be utilised to optimise the hauler transport mission on its own or as a part in a larger optimal control problem involving several construction machines working together on a site transporting material at a set production rate. While rolling resistance is a major energy consumer in an articulated hauler’s transport, the effect of varying rolling resistance is included in the developed optimisation algorithm. A method utilising Extended Kalman Filter, Rauch-Tung-Striebel smoothing and sensor fusion is formulated in order to calculate the road related data needed in the optimisation algorithm. A potential fuel efficiency improvement, verified by computer simulations, of up to 9% was found in the example transport mission where the optimal gear and speed trajectory were followed instead of driving towards a mean speed target to achieve an equal cycle time for the transport mission.
Speech and language development in 2-year-old children with cerebral palsy

Objective: We examined early speech and language development in children who had cerebral palsy. Questions addressed whether children could be classified into early profile groups on the basis of speech and language skills and whether there were differences on selected speech and language measures among groups. Methods: Speech and language assessments were completed on 27 children with CP who were between the ages of 24 and 30 months (mean age 27.1 months; SD 1.8). We examined several measures of expressive and receptive language, along with speech intelligibility. Results: Two-step cluster analysis was used to identify homogeneous groups of children based on their performance on the seven dependent variables characterizing speech and language performance. Three groups of children identified were those not yet talking (44% of the sample); those whose talking abilities appeared to be emerging (41% of the sample); and those who were established talkers (15% of the sample). Group differences were evident on all variables except receptive language skills. Conclusion: 85% of 2-year-old children with CP in this study had clinical speech and/or language delays relative to age expectations. Findings suggest that children with CP should receive speech and language assessment and treatment at or before 2 years of age.
Aerodynamic consequences of wing morphing during emulated take-off and gliding in birds

ABSTRACT Birds morph their wings during a single wingbeat, across flight speeds and among flight modes. Such morphing may allow them to maximize aerodynamic performance, but this assumption remains largely untested. We tested the aerodynamic performance of swept and extended wing postures of 13 raptor species in three families (Accipitridae, Falconidae and Strigidae) using a propeller model to emulate mid-downstroke of flapping during take-off and a wind tunnel to emulate gliding. Based on previous research, we hypothesized that (1) during flapping, wing posture would not affect maximum ratios of vertical and horizontal force coefficients (CV:CH), and that (2) extended wings would have higher maximum CV:CH when gliding. Contrary to each hypothesis, during flapping, extended wings had, on average, 31% higher maximum CV:CH ratios and 23% higher CV than swept wings across all biologically relevant attack angles (α), and, during gliding, maximum CV:CH ratios were similar for the two postures. Swept wings had 11% higher CV than extended wings in gliding flight, suggesting flow conditions around these flexed raptor wings may be different from those in previous studies of swifts (Apodidae). Phylogenetic affiliation was a poor predictor of wing performance, due in part to high intrafamilial variation. Mass was only significantly correlated with extended wing performance during gliding. We conclude that wing shape has a greater effect on force per unit wing area during flapping at low advance ratio, such as take-off, than during gliding. Summary: Wing posture has a greater effect on aerodynamic performance during emulated flapping than during emulated gliding. Extended wing morphology (i.e. emarginate primaries) may be more important during take-off and landing than during gliding.
Novel MITF targets identified using a two‐step DNA microarray strategy

Malignant melanoma is a chemotherapy‐resistant cancer with high mortality. Recent advances in our understanding of the disease at the molecular level have indicated that it shares many characteristics with developmental precursors to melanocytes, the mature pigment‐producing cells of the skin and hair follicles. The development of melanocytes absolutely depends on the action of the microphthalmia‐associated transcription factor (MITF). MITF has been shown to regulate a broad variety of genes, whose functions range from pigment production to cell‐cycle regulation, migration and survival. However, the existing list of targets is not sufficient to explain the role of MITF in melanocyte development and melanoma progression. DNA microarray analysis of gene expression offers a straightforward approach to identify new target genes, but standard analytical procedures are susceptible to the generation of false positives and require additional experimental steps for validation. Here, we introduce a new strategy where two DNA microarray‐based approaches for identifying transcription factor targets are combined in a cross‐validation protocol designed to help control false‐positive generation. We use this two‐step approach to successfully re‐identify thirteen previously recorded targets of MITF‐mediated upregulation, as well as 71 novel targets. Many of these new targets have known relevance to pigmentation and melanoma biology, and further emphasize the critical role of MITF in these processes.
Genomics: An In Vitro Toxicology Point of View

Genomics, and in particular its derived discipline, toxicogenomics, are rapidly developing technologies, which permit studies on the impact of chemicals and drugs on gene expression in particular biological systems. Enormous amounts of data will be provided in the context of mechanistic and predictive toxicology from the use of the DNA microarray approach for the simultaneous analysis of the expression pattern of multiple genes. The high-throughput requirement of these approaches necessitates in vitro cell culture systems. This article will give a short overview of the areas of ECVAM's research in which this technology will initially be applied.
3-D Recovery of a Non-rigid Object from a Single Camera View Employing Multiple Coordinates Representation

This paper proposes a novel technique for 3-D recovery of a non-rigid object, such as a human in motion, from a single camera view. To achieve the 3-D recovery, the proposed technique performs segmentation of an object under deformation into respective parts which are all regarded as rigid objects. For high accuracy segmentation, multi-stage learning and local subspace affinity are employed for the segmentation. Each part recovers its 3-D shape by applying the factorization method to it. Obviously the deformed portion containing twist or stretch motion cannot recover the 3-D shape by this procedure. The idea of the present paper is to recover such deformed portion by averaging the 3-D locations of a point on the portion described by the coordinates of respective parts. The experiments employing a synthetic non-rigid object and real human motion data show effectiveness of the proposed technique.