Miracle-dz/UniFAR-FTUs huggingface dataset:
Twin pregnancy consisting of 46, XY heterozygous complete mole coexisting with a live fetus.

Complete hydatidiform mole and coexistent fetus (CMCF) is a rare occurrence and is associated with an increased risk of persistent gestational trophoblastic diseases. The aim of this study was to reveal a potential risk factor and to determine optimum management of CMCF cases. Molar tissues are cytogenetically divided into two types, homozygous and heterozygous. The molar tissue of our case showed a 46, XY heterozygous complete mole. Genomic DNA was analyzed by the polymerase chain reaction using sets of unlabelled forward and Cy-5-labelled reverse primers for DNA marker loci. The patient developed persistent trophoblastic disease (PTD) with lung metastasis. Since 1980 there have been 13 reports (including our case) that cytogenetically revealed CMCF and clarified the clinical outcome. Nine of the 16 CMCF cases before 21 weeks of gestation and seven of the 12 CMCF cases after 22 weeks of gestation developed PTD. The incidence of PTD from CMCF was not related to the gestational age at termination or delivery. There were 10 case reports that analyzed the zygosity of a mole, heterozygous or homozygous. Two of six homozygous and three of four heterozygous moles in CMCF cases developed PTD. A heterozygous mole is thought to be a high risk factor for the incidence of PTD. Cytogenetic study is clinically useful for the optimum management of CMCF cases.
Temporal Patterns : An Information Theoretic Approach

Interesting patterns in temporal databases have equivalently been treated in literature as novelties or surprises. In this paper we propose a Information Theoretic framework for detecting interestingness that can handle most subjective notions of what might be interesting in temporal data . Based on this framework, a mutual information measure is derived using kernel based nonparametric probability density estimation techniques to assess interestingness of a temporal sub-sequence given another. This measure is then utilized in a sliding windows algorithm to detect all possible interesting sub-sequences with respect to a reference sequence. The algorithm’s effectiveness is shown to be independent of the parameter choice for the density estimates and its advantages over other prominent techniques are discussed.
Efficient In-band Service Announcement Through IPv6 Address Encoding

The announcement and discovery of network services represents one of the most important functionalities in today's networks. In order to find and use services provided by remote systems, service management and dedicated service discovery protocols are used. These mechanisms introduce, however, additional overhead, especially in resource-constrained environments such as sensor networks. In this paper, we propose an in-band service announcement mechanism through IPv6 address encoding. In this scheme, IPv6's large address space is used by a system to encode its service information into the host part of its IPv6 address. This information can then be extracted and efficiently used by other systems, allowing for service announcement without the need for additional protocols.
Active learning in annotating micro-blogs dealing with e-reputation

Elections unleash strong political views on Twitter, but what do people really think about politics? Opinion and trend mining on micro blogs dealing with politics has recently attracted researchers in several fields including Information Retrieval and Machine Learning (ML). Since the performance of ML and Natural Language Processing (NLP) approaches are limited by the amount and quality of data available, one promising alternative for some tasks is the automatic propagation of expert annotations. This paper intends to develop a so-called active learning process for automatically annotating French language tweets that deal with the image (i.e., representation, web reputation) of politicians. Our main focus is on the methodology followed to build an original annotated dataset expressing opinion from two French politicians over time. We therefore review state of the art NLP-based ML algorithms to automatically annotate tweets using a manual initiation step as bootstrap. This paper focuses on key issues about active learning while building a large annotated data set from noise. This will be introduced by human annotators, abundance of data and the label distribution across data and entities. In turn, we show that Twitter characteristics such as the author's name or hashtags can be considered as the bearing point to not only improve automatic systems for Opinion Mining (OM) and Topic Classification but also to reduce noise in human annotations. However, a later thorough analysis shows that reducing noise might induce the loss of crucial information.
Organizational Well-Being and Communication in a Medical Setting

This study examines the relationship between work engagement, organizational commitment and group-level communication in a hospital setting. Social network analysis was used to examine the structure and usefulness of communication in a small group representing diverse responsibilities in a hospital setting. Personnel included physicians, specialist physicians, nurses, unit clerks, and senior administrators (N = 30). A pre-test, intervention, post-test design was used. In the intervention, participants reviewed pre-test results and made recommendations to improve communication. In this sample, relationships were observed between engagement, perceptions of useful communication and individual positions in the network. Participants reported a significant increase in work engagement and number of communication connections. Medical well-being and communication! May 4, 2010 Ian MacRae (ianmacrae@gmail.com! 2/40
Trade and Innovation: Matched Worker-Firm-Level Evidence

This paper examines the relationship between globalization and innovation. To do so, it draws from data that match the full population of workers and private-sector firms in Finland tracking them from 1995 to 2009. To correct for endogeneity the paper considers variation in trade exposure from China during its entry to the world market using a fixed effects model. While the literature on trade and innovation has emphasized the role of firms in driving onshore innovation, the main conclusion of this research is that globalization increases the share of innovators within firms.
Type I atelocollagen grafting onto ozone-treated polyurethane films: cell attachment, proliferation, and collagen synthesis.

An approach is presented for the graft copolymerization of type I atelocollagen onto the surface of polyurethane (PU) films treated with ozone. Through inducing oxidization to modify PU surface by ozone, peroxide groups are easily generated on the surface. Those peroxides are broken by redox-polymerization, and provide active species which initiate graft polymerization by reacting with amines in the collagen molecules. The ozone oxidation time and voltage could readily control the amount of peroxide production. The surface density of generated peroxides on PU surface was determined by iodide method. The maximum concentration of peroxide was about 10.20 x 10(-8)mol/cm(2) when ozone oxidation was performed at 60 V for 30 min. After the reaction of PU by ozone oxidation, type I atelocollagen was graft-copolymerized onto the PU film. All the physical measurements on the collagen-grafted surface indicated that the PU surface was effectively covered with type I atelocollagen. The interaction of the collagen-grafted PU surface with fibroblasts could be greatly enhanced by the surface graft polymerization with type I atelocollagen. Attachment and proliferation of fibroblasts on the grafted type I atelocollagen were significantly enhanced, and it is assumed that the atelocollagen matrix supported the initial attachment and growth of cells. In the early stage of proliferation, collagen synthesis in fibroblasts was not activated and remained at a relatively low level due to the grafted type I atelocollagen, increasing only with fibroblast differentiation.
Acute demyelination disrupts the molecular organization of peripheral nervous system nodes

Intraneurally injected lysolecithin causes both segmental and paranodal demyelination. In demyelinated internodes, axonal components of nodes fragment and disappear, glial and axonal paranodal and juxtaparanodal proteins no longer cluster, and axonal Kv1.1/Kv1.2 K+ channels move from the juxtaparanodal region to appose the remaining heminodes. In paranodal demyelination, a gap separates two distinct heminodes, each of which contains the molecular components of normal nodes; paranodal and juxtaparanodal proteins are properly localized. As in normal nodes, widened nodal regions contain little or no band 4.1B. Lysolecithin also causes “unwinding” of paranodes: The spiral of Schwann cell membrane moves away from the paranodes, but the glial and axonal components of septate‐like junctions remain colocalized. Thus, acute demyelination has distinct effects on the molecular organization of the nodal, paranodal, and juxtaparanodal region, reflecting altered axon–Schwann cell interactions. J. Comp. Neurol. 479:424–434, 2004. © 2004 Wiley‐Liss, Inc.
First experience with the St Jude Medical, Inc, Symmetry Bypass System (Aortic Connector System).

Using the saphenous vein graft in coronary artery bypass grafting, the proximal anastomosis is usually performed by running sutures with a partial occlusion clamp. This technique is bearing the risk of immediate or delayed aortic dissection induced by the heel of a partial occlusion clamp,1 especially in the case of a diseased aortic wall or poor suturing technique. If atheroma or calcification of the aortic wall are present, clamping is often impossible, and it remains unclear whether the use of the partial occlusion clamps on the pulsating aorta during off-pump surgery will increase the risk of iatrogenic injuries. However, the St Jude Medical, Inc, Symmetry Bypass System (Aortic Connector System [ACS]) presents an alternative way of creating the proximal anastomosis of saphenous vein grafts.2 It avoids aortic bite clamping and reduces the need for aortic manipulation.
Fast configurable polynomial division for error control coding applications

The motivation for this paper is the need for high levels of reliability in modern telecommunication systems requiring very high data transmission rates. The search for technologically independent solutions, easy to implement on low cost and popular devices such as FPGA is an important issue. In this paper, we present a method to improve effectively the speed performance of the polynomial division performed in most error detecting and error correcting circuits. It is based on a pipeline structure for the polynomial division. Furthermore, the proposed solution is fully configurable, both from the static and the dynamic points of view. At synthesis stage, the parallelism level (size of the pipeline structure) and the maximal size of the polynomial divisor must both be chosen. Afterwards, the actual divisor can be chosen and changed while the circuit is running. The architecture proved to be very effective, as data rates up to 2.5 Gbits/s have been reached.
The relationship between risk management and financial performance of the top 100 small and medium enterprises in Kenya

v TABLE OF CONTENTS . vi LIST OF TABLES . ix LIST OF FIGURES . x LIST OF ABBREVIATIONS . xi CHAPTER ONE: INTRODUCTION . 1 1.1 Background to the Study . 1 1.1.2 Financial Performance . 3 1.1.3 Effects of Risk Management on Financial Perfo rmance . 5 1.1.4 Small and Medium Enterprises in Kenya . 6 1.2 Research Problem . 8 1.3 Research Objective . 11 1.4 Value of the Study . 11 CHAPTER TWO: LITERATURE REVIEW . 12 2.
Synthesis of Piperoyl Coenzyme A Thioester

Piperoyl-CoA, a potential intermediate in the biosynthesis of piperine. the pungent principle of pepper, was synthesized via N-succinimidyl piperate and subsequent transesterification with CoA- SH. UV-spectrophotometry of the HPLC-purified compound revealed, besides a maximum at 260 nm, a pronounced second absorption maximum at 368 nm due to the thioester linkage for which, as determined via the Fe3+-complex of piperoyl hydroxamate and with [14C]piperoyl-CoA, a molar extinction coefficient of 30.8 × 106 [cn2mol-1] was calculated.
Blood pressure levels and hypertension in persons ages 6-74 years: United States, 1976-80.

Hypertension or substantially elevated blood pres­ sure is one of the more prevalent chronic conditions lmownto increase the risk ofdevelopingcirculatory dis­ eases, particularly heart disease and stroke. 1-4 Circula­ ory diseases are the leading cause of death and of hos­ e pitalization in the United States. This report presents national estimates for blood pressure levels, the preva­ lence of known and previously undiagnosed hyperten­ sion, and the extent of use of antihypertensive medica­ tion in the general U.S. population during the period 1976–80. The data are from the second National Health and Nutrition Examination Survey, which used a probability cross-sectional sample of the civilian noninstitutionalized population ages 6–74 years in the United States, including Alaska and Hawaii.s Trends since 1960 in the extent of treatment awareness, and control among those with hypertension are also shown.
Voice Recognition and Identification System ( Text Dependent Speaker Identification ) Final Report 18-551 Digital Communications and Signal Processing Systems Design Spring 2000

In order to solve the problem of unwanted access to systems, we proposed a Text Dependent Speaker Identification System that uses two features to keep out intruders. If a user wanted to gain access, both the userÕs voice and his/her personal password will need to be recognized and authenticated by the security system. Even if an unauthorized user could obtain a sample of an authorized userÕs voice, access to the system will not be granted without the proper password. Ê These two features build redundancy into the security system, making it difficult for intruders to get it.
Toward a Culturally Inclusive Understanding of Wisdom: Historical Roots in the East and West

To establish a clearer definition of wisdom as a psychological concept, Western and Eastern historical literatures were reviewed and assessed within a general analytical/synthetic framework. In the West, either in an ancient Egyptian, biblical, or philosophical sense, wisdom had been often identified as a form of analytical ability such as an increase in the knowledge database or an increase in information processing efficiency. By contrast, the Eastern understanding of wisdom, primarily derived from the ancient Vedic text, had been more inclusive, with both analytical and synthetic domains regarded as necessary moments to the whole of wisdom. The inclusive account was also discussed with respect to two important Eastern themes of wisdom: “void” and “codependence. ”
Association of the functional catechol-O-methyltransferase VAL158MET polymorphism with the personality trait of extraversion

Across different personality theories, there is agreement that dopamine is the neurochemical basis of extraversion. However, evidence from molecular genetics for the validity of this hypothesis is far from convincing. The functional polymorphism of the catechol-O-methyltransferase gene (COMT VAL158MET) has not been related to extraversion before, although it is a promising candidate gene locus for extraversion because of its great influence on the catabolism of dopamine. In a sample of n=363 healthy study participants, the catechol-O-methyltransferase VAL158MET polymorphism was related to extraversion and novelty seeking.Results showed a significant association between catechol-O-methyltransferase, extraversion and the subscale exploratory excitement (NS1) of novelty seeking but not with the total novelty-seeking scale supporting the psychometric analyses of the personality scales. The findings support the hypothesis that the dopamine system is involved in positive emotionality and incentive motivation, which has implications for the understanding of the neurochemical correlates of normal and psychopathological behaviors.
Influence of the environment on activity performance in older women with heart failure

Purpose. To examine the influence of the environment on activity performance in older women with heart failure living in the community. Method. The cross-sectional study included 55 older women with heart failure. Differences in activity performance collected through performance observation in the clinic and home were analysed with repeated measures ANOVAs and paired samples t-tests. Results. Overall, the influence of the environment in the clinic was neutral for activity independence, and disabling for activity safety and activity adequacy at the global level. At the domain level, functional mobility and personal care were more independent but equally safe and adequate in the clinic compared to the home, cognitively-oriented instrumental activities were less independent, safe and adequate in the clinic compared to the home, and physically-oriented instrumental activities were equally independent, but less safe and adequate in the clinic compared to the home. At the activity level, 6 activities were positively influenced by the environment in the clinic and 13 activities were negatively influenced. Conclusions. Findings suggest that the influence of the environment can be neutral, enabling, or disabling depending on the global scores or level of analysis being considered.
Glucose Concentration can be Predicted Ahead in Time From Continuous Glucose Monitoring Sensor Time-Series

A clinically important task in diabetes management is the prevention of hypo/hyperglycemic events. In this proof-of-concept paper, we assess the feasibility of approaching the problem with continuous glucose monitoring (CGM) devices. In particular, we study the possibility to predict ahead in time glucose levels by exploiting their recent history monitored every 3 min by a minimally invasive CGM system, the Glucoday, in 28 type 1 diabetic volunteers for 48 h. Simple prediction strategies, based on the description of past glucose data by either a first-order polynomial or a first-order autoregressive (AR) model, both with time-varying parameters determined by weighted least squares, are considered. Results demonstrate that, even by using these simple methods, glucose can be predicted ahead in time, e.g., with a prediction horizon of 30 min crossing of the hypoglycemic threshold can be predicted 20-25 min ahead in time, a sufficient margin to mitigate the event by sugar ingestion
Information logistics and wearable computing

In this paper, we introduce the information logistics concept and demonstrate its relevance for the field of wearable computing. Information logistics is an innovative technology based on the idea that the right information gets to the recipient, e.g. journalist at the right time. The objective is a need- and user-oriented information supply according to just-in-time principles. The Smart-Wear project is a first step towards a personalized, wearable information broker based on the information logistics concept. In this paper, we want to illustrate the complexity of such a project aiming to deliver "information skin-deep". We therefore present the underlying idea as well as the system architecture. We furthermore summarize the experiences and results of the customer study as user acceptance proves to be one of the major tasks of wearable computing due the impact such technologies have on the users.
Bile acid‐binding activity of young persimmon (Diospyros kaki) fruit and its hypolipidemic effect in mice

The hypolipidemic effects and bile acid‐binding properties of young persimmon (Diospyros kaki) fruit were examined. In an animal experiment, male C57BL/6.Cr mice (n = 5) were fed an AIN‐76‐modified high fat diet supplemented with 2% or 5% (w/w) dried young persimmon fruit (YP) for 10 weeks. The intake of YP significantly enhanced fecal bile acid excretion and lowered the concentration of hepatic lipids and plasma cholesterol. Analysis of gene expression in liver tissue showed that 2% or 5% YP up‐regulated the expression of the sterol regulatory element‐binding protein‐2 gene. In the 5% group, there were increased expressions of the genes for cholesterol 7α‐hydroxylase and the low‐density lipoprotein receptor. Next, the bile acid‐binding ability of YP was analysed in vitro using cholic acid (CA). In 100–2000 µM CA solutions, 1% (w/v) YP adsorbed approximately 60% of CA, while dried mature persimmon fruit adsorbed approximately 20% of CA. The positive control, cholestyramine, adsorbed approximately 80% of CA in the 100–2000 µM CA solutions. A crude tannin extract from YP, which contained 54.7% condensed tannins, adsorbed approximately 78% of CA in the 2000 µM CA solutions. These results suggest that the ability of YP to bind bile acid contributes to its hypolipidemic effect in mice. Copyright © 2009 John Wiley & Sons, Ltd.
Neural precursor cells differentiating in the absence of Rb exhibit delayed terminal mitosis and deregulated E2F 1 and 3 activity.

The severe neurological deficit in embryos carrying null mutations for the retinoblastoma (Rb) gene suggests that Rb plays a crucial role in neurogenesis. While developing neurons undergo apoptosis in vivo neural precursor cells cultured from Rb-deficient embryos appear to differentiate and survive. To determine whether Rb is an essential regulator of the intrinsic pathway modulating terminal mitosis we examined the terminal differentiation of primary cortical progenitor cells and bFGF-dependent neural stem cells derived from Rb-deficient mice. Although Rb -/- neural precursor cells are able to differentiate in vitro we show that these cells exhibit a significant delay in terminal mitosis relative to wild-type cells. Furthermore, Rb -/- cells surviving in vitro exhibit an upregulation of p107 that is found in complexes with E2F3. This suggests that p107 may partially compensate for the loss of Rb in neural precursor cells. Functional ablation of Rb family proteins by adenovirus-mediated delivery of an E1A N-terminal mutant results in apoptosis in Rb-deficient cells, consistent with the interpretation that other Rb family proteins may facilitate differentiation and survival. While p107 is upregulated and interacts with the putative Rb target E2F3 in neural precursor cells, our results indicate that it clearly cannot restore normal E2F regulation. Rb-deficient cells exhibit a significant enhancement of E2F 1 and 3 activity throughout differentiation concomitant with the aberrant expression of E2F-inducible genes. In these studies we show that Rb is essential for the regulation of E2F 1 and 3 activity as well as the onset of terminal mitosis in neural precursor cells.