Miracle-dz/UniFAR-FTUs huggingface dataset:
Neighborhood crime, the housing crisis, and geographic space: Disentangling the consequences of foreclosure and vacancy

ABSTRACT In the wake of the U.S. housing crisis, a flurry of research has examined the consequences of foreclosure for crime, and much of the literature suggests that foreclosure impacts crime through vacancy. We suggest that foreclosure and vacancy have distinct crime processes and their effects should be examined in tandem. Furthermore, the spatial distribution of foreclosure and vacancy, particularly in surrounding neighborhoods, may have different consequences for crime. We examine these questions using quarterly neighborhood data from Cleveland, Ohio, from 2006 to 2011 for both property and violent crimes. We find that foreclosures only impact crime through the broader nearby area, whereas vacancies appear to only be of consequence within the focal neighborhood. Our findings suggest distinct and spatialized differences between foreclosures and vacancies in their consequences for crime.
CDC14B Acts Through FZR1 (CDH1) to Prevent Meiotic Maturation of Mouse Oocytes1

Abstract Meiotic maturation in oocytes is a prolonged process that is unique because of cell cycle arrests at prophase of meiosis I (MI) and at metaphase of meiosis II (MII). Fluctuations in cyclin-dependent kinase 1 (CDK1/CDC2A) activity govern meiotic progression, yet little is known about how these fluctuations are achieved. CDC14 is a highly conserved dual-specificity phosphatase that counteracts the function of proteins phosphorylated by CDK. Mammals contain two CDC14 homologs, CDC14A and CDC14B. We report that CDC14B localizes with the meiotic spindle in mouse oocytes, and (unlike somatic cells) it does not localize in the nucleolus. Oocytes that overexpress CDC14B are significantly delayed in resuming meiosis and fail to progress to MII, whereas oocytes depleted of CDC14B spontaneously resume meiosis under conditions that normally inhibit meiotic resumption. Depletion of FZR1 (CDH1), a regulatory subunit of the anaphase-promoting complex/cyclosome that targets cyclin B1 (CCNB1) for ubiquitin-mediated proteolysis, partially restores normal timing of meiotic resumption in oocytes with excess CDC14B. These studies also reveal that experimentally altering CDC14B levels generates eggs with abnormal spindles and with chromosome alignment perturbations. Our data indicate that CDC14B is a negative regulator of meiotic resumption and may regulate MI in mouse oocytes.
Alveolar echinococcosis: how knowledgeable are primary care physicians and pharmacists in the Franche-Comté region of France?

Background: Alveolar echinococcosis (AE) is a parasitic disease resulting from the intrahepatic growth of Echinococcus multilocularis larva. This zoonotic helminthic disease is rare but, if left untreated or treated too late, can be severe or even fatal. In France, endemic areas containing infected foxes have become larger, spreading towards western regions of the country and leading to an increased risk of environmental contamination. An observational survey was undertaken in 2014 to assess the level of knowledge of AE among primary care physicians (PCPs) and pharmacists in the Franche-Comté region. Methods: Standardized questionnaires were sent to a random sample of 183 PCPs and 236 pharmacists practicing in the Franche-Comté region (eastern France), requesting their voluntary and anonymous participation. The questionnaires collected socio-demographic details, self-evaluation and asked multiple choice questions (MCQs) about epidemiology, prevention, diagnosis and management of AE. Results: The crude response rate was 37.5% of the PCPs and pharmacists questioned. Responses to MCQs showed that most of the participating PCPs and pharmacists had acceptable basic knowledge of AE, especially concerning epidemiology and prevention of the disease. However, a serious lack of knowledge was observed concerning the management of AE. Conclusion: PCPs are often the first health professionals to suspect latent AE, which is still a rural disease in France. Both PCPs and pharmacists play an important role in informing and referring patients potentially exposed to AE. This study shows that although AE is rare, PCPs and pharmacists of the Franche-Comté region have a satisfactory level of knowledge of AE.
Is one question enough to screen for depression?

Aims: The aim of this study was to determine if chronic pain patients with symptoms of depression could be identified by one single question. Methods: Data from 595 patients, 55% women, and 45% men, from three different patient populations; low back pain patients (n = 387), whiplash patients (n = 119), and disability pensioners (n = 89), were analysed. We evaluated the test characteristics of one question on depression from the Subjective Health Complaints (SHC) Inventory. The respondents report if, and to what extent, they have been affected by sadness/depression in the last 30 days. The Hopkins Symptom Checklist-25 (HSCL-25) was used as the criterion standard. HSCL-25 is a self-report symptom rating scale with two dimensions: depression and anxiety. ‘‘Depressed’’ was defined as having a score above 1.75 on the depression subscale. Results: Thirty-three per cent of the patients were depressed according to HSCL-25. The sensitivity of the single SHC depression-question was 79%, and the specificity was 81%. Positive predictive value was 67% while negative predictive value was 89%. Kappa value for all groups combined was 0.58 (p < 0.001). The receiver operating characteristic (ROC) curve showed an area under the curve of 0.83. Conclusions: The depression-question from SHC identified most of the depressed patients measured by HSCL-25 in low back pain patients, whiplash patients, and disability pensioners, and can therefore be considered an indicator of depression. Satisfactory sensitivity and specificity were detected, as well as similar responsiveness as determined by the ROC analyses. The results indicate that one simple question could replace a whole questionnaire (HSCL-25) in identifying depressive patients.
Molecular Identification of Novel Alpha- and Gammaherpesviruses from Cetaceans Stranded on Japanese Coasts

Herpesviral infections have been documented in some cetaceans; however, they have not yet been identified in species in the western North Pacific. In the present study, 178 tissue samples from 76 stranded cetacean individuals were tested for the presence of herpesviruses. Herpesvirus genomic DNA fragments surrounding the DNA polymerase gene were amplified in samples from four individuals. TA cloning and direct sequencing of these DNA fragments revealed the presence of two novel alphaherpesviruses, and two novel gammaherpesviruses in the four cetacean individuals. The alphaherpesviruses were associated with the lung tissue of a false killer whale (Pseudorca crassidens), and with the mucus of a melon-headed whale (Peponocephala electra). The gammaherpesviruses were found in the lymph tissues of a Stejneger's beaked whale (Mesoplodon stejnegeri) and a sperm whale (Physeter macrocephalus). The phylogenetic tree using amino acid sequences of the DNA polymerase gene supported the inclusion of the novel viruses identified here in a single monophyletic group containing alphaherpesviruses from other Atlantic cetacean species. Conversely, the novel gammaherpesviruses formed an independent clade distant from other known cetacean gammaherpesviruses.
Adsorption of Chlorinated Phenols from Aqueous Solution By Surfactant-Modified Pillared Clays

New pillared clay-based adsorbents have been prepared by incorporating a nonionic surfactant of general formula C12–14H25–29O(CH2CH2O)5H (commercial name, Tergitol 15S-5), during the synthesis of the aluminum hydroxide pillaring reagent. Different loadings of surfactant have been examined. The presence of the surfactant enhanced the adsorption capacity of the clay toward 3-monochlorophenol from aqueous solution. On the basis of adsorption results for a series of clays with increasing surfactant loadings, the best adsorbent was obtained at a surfactant loading of 255 mg/g of clay. At this loading, the surfactant occupies the micropores, as well as the mesopores and the external surfaces of the pillared clay. Analysis of the adsorption isotherms for 3-monochlorophenol, 3,5-dichlorophenol, 3,4,5-trichlorophenol and pentachlorophenol at different pH shows that the most energetic adsorption sites are the surfactant-occupied micropores between pillars. Additional binding of chlorinated phenols occurs at surfactant sites on external surfaces and mesopores. Upon calcination at 500°C, the clay is converted to a conventional alumina-pillared clay with a basal spacing near 16 Å. This calcined product can be reused as an adsorbent for chlorinated phenols by readsorbing fresh surfactant. The recycled adsorbent exhibits performance properties comparable to the original adsorbent. These results demonstrate the feasibility of utilizing a surfactant-modified pillared clay as a recyclable adsorbent and combustion catalyst for environmental pollutants.
Institutions and Economic Growth: Sharpening the Research Agenda

After a long hiatus, "institutions" again is a fashionable term in the vocabulary of professional economists. Indeed, there is widespread agreement that the right institutions are the key to economic productivity and progressiveness, but beneath this apparent consensus lies something of a muddle. There are several different definitions of what institutions are and what they do. Most analyses that purport to identify the "right" institutions are superficial and unpersuasive. And, there are serious questions regarding why societies have the institutions they do at any time and their ability to deliberately improve them. My argument is that the conglomerate of things different economists have called institutions largely reflects the fact that many different kinds of structures and forces mold the way individuals and organizations interact to get things done. Many different institutions are needed, and the institutions that are effective are very context dependent. I argue that economic growth involves the co-evolution of technologies and the institutions needed for their effective operation and advancement. Some institutions provide the broad background conditions under which technological change can proceed, and others come into existence and develop to support the important new technologies that are driving growth. Institutional change, and its influence on economic activity, is much more difficult to direct and control than technological change, and hence prevailing institutions are often drags on economic productivity and progressiveness.
Fisher information and entanglement of non-Gaussian spin states

Subtle entanglement in an atomic cloud In the quantum world, atoms can be correlated with each other—“entangled”—which reduces the uncertainty in the knowledge of some of their properties. Physicists then use this reduced uncertainty to perform precision measurements. Strobel et al. made an unusual type of entangled state consisting of hundreds of ultracold Rb atoms. These methods may in the future be able to generate states that will be more useful in precision measurement. Science, this issue p. 424 An unconventional entangled state is created out of a mesoscopic number of ultracold rubidium atoms. Entanglement is the key quantum resource for improving measurement sensitivity beyond classical limits. However, the production of entanglement in mesoscopic atomic systems has been limited to squeezed states, described by Gaussian statistics. Here, we report on the creation and characterization of non-Gaussian many-body entangled states. We develop a general method to extract the Fisher information, which reveals that the quantum dynamics of a classically unstable system creates quantum states that are not spin squeezed but nevertheless entangled. The extracted Fisher information quantifies metrologically useful entanglement, which we confirm by Bayesian phase estimation with sub–shot-noise sensitivity. These methods are scalable to large particle numbers and applicable directly to other quantum systems.
The Histopathological and Clinical Relevance of Apoptotic Cell Death in Medulloblastomas

We studied apoptosis in 40 medulloblastomas by in situ end labeling (ISEL) of DNA strand breaks. In situ end labeling was performed on paraffin-embedded material from classical and desmoplastic medulloblastomas and medulloblastomas with glial and combined differentiation. The number of labeled apoptotic cells varied considerably from tumor to tumor as well as between different areas in the same tumor. However, there was no significant difference in the averaged numbers or in the pattern of apoptotic tumor cells between the different differentiations of medulloblastoma. Unlabeled tumor cells displaying features of apoptosis were found in small numbers, indicating that tumor cells may also be able to undergo cell death different from classical apoptosis. A significantly higher number of apoptotic tumor cells in male patients could be demonstrated corresponding to the reported difference in survival rates between male and female patients suffering from medulloblastoma. A clear cut trend of a negative relation between apoptosis and age by operation was found.
Analytical and Microbiological Characterization of Paper Samples Exhibiting Foxing Stains

Abstract This work comprises the use of a multi-analytical approach combined with microbiological studies to characterize six paper samples, containing foxing stains, from the 20th century, regarding their cellulose matrix, fillers, and sizing materials, and to evaluate possible paper degradation that might have occurred during the foxing stains. Photography under different illuminations and optical microscopy were used for morphological characterization of the paper samples and foxing stains. Scanning electron microscopy coupled energy dispersive spectroscopy (SEM-EDS) was of particular importance for defining the presence of fiber disorder and disruption on the surface of some of the stains, and localized accumulations of mineral-like particles on the surface of others. SEM-EDS, attenuated total reflection Fourier transform infrared spectroscopy (ATR-FT-IR), and energy dispersive X-ray fluorescence (EDXRF) were used for the identification of mineral fillers, whereas sizing agents were analyzed using ATR-FT-IR. EDXRF results showed that no differences, within the standard deviation, were found in iron and copper contents between the foxed and unfoxed areas. Fungi belonging to the genus Penicillium spp. were found in all the paper samples. Unfoxed areas presented lower contamination than the foxed areas.
Oral Treatment with Probiotics Reduces Allergic Symptoms in Ovalbumin-Sensitized Mice: A Bacterial Strain Comparative Study

Background/Aim: Evidence demonstrating an important role of the intestinal microbiota in the incidence of allergic disorders has led to the concept of using probiotics as possible antiallergic therapy. This study aimed to select a bacterial strain with the best antiallergic treatment effects from a panel of 6 bacterial strains in a mouse model of ovalbumin(OVA)-allergic asthma. Methods: OVA-sensitized BALB/c mice were orally administered the bacterial strains Bifidobacterium breve M-16V, B. infantis NumRes251, B. animalis NumRes252 and NumRes253, Lactobacillus plantarum NumRes8 and L. rhamnosus NumRes6. After challenge by OVA inhalation in the lungs, the response to methacholine was measured. Pulmonary inflammation was assessed by analyzing bronchoalveolar lavage fluid for the presence of eosinophils, neutrophils, macrophages and lymphocytes and for interleukin 4, interleukin 5, interleukin 10 and interferon-γ. OVA-specific IgE, IgG1 and IgG2a were measured in serum. Next, the effect on acute allergic skin reaction was measured after treatment with B. breve M-16V and L. plantarum NumRes8. Results: Of the panel of 6 strains, B. breve M-16V and L. plantarum NumRes8 inhibited (1) the response to methacholine, (2) reduced the number of eosinophils in the bronchoalveolar lavage fluid, (3) reduced both OVA-specific IgE and (4) OVA-specific IgG1, whereas the other strains did not affect all these parameters simultaneously. B. breve M-16V but not L. plantarum NumRes8 reduced interleukin 4, interleukin 5 and interleukin 10. Furthermore, B. breve M-16V but not L. plantarum NumRes8 reduced acute allergic skin reactions to OVA. Conclusion: B. breve M-16V was identified as the most potent antiallergic strain.
Executive directors' compensation and monitoring: the influence of gender diversity on Spanish boards

AbstractThis study presents evidence of the influence of gender diversity on the pay system and the monitoring of executives in Spain. In this country/context, characterized by a few male dominant shareholders acting simultaneously as executives, there is an ongoing discussion regarding the enactment of laws to promote gender equality on the boards of directors of large listed companies. This paper presents several contributions. On the one hand, the scarce previous evidence on this topic is focused on US firms. On the other hand, this study includes the role of ownership structure as a factor that indirectly moderates the relationships between gender diversity on board and monitoring effectiveness in terms of executive directors’ compensation. Furthermore, this paper makes an important effort to control endogeneity. The sample examined includes 120 companies listed on the Spanish stock market during the period 2004–2011. The results show a positive and highly significant effect of the presence of women i.
Exchange Rates and the Yield Curve

In this paper, we confront the data with the financial markets folk wisdom that an increase in a yield or forward rate of country i relative to j is associated with a contemporaneous appreciation of currency i. We find that while the folk wisdom prior to 2009:Q1 holds fairly well for all maturities and three major currency bases, the “coefficient curve” twisted during the zero-lower-bound period so that the relationship became stronger at the short end but weaker and even of the opposite sign at the long end of the curve. We attribute the structural breaks at the short end of the curve to a change in the relationship between expected excess currency returns and changes in relative yields/forwards. The breaks at the long end of the curve can be explained by changing relationships between yields/forwards and the part of exchange rate fluctuations due to changes in expectations over future short-term rates and long-run relative price levels. Alternatively, the twist of the coefficient curve can be attributed to the changing relationship between the exchange rate and the expectation hypothesis component of yields/forwards at the short end and the term premium component at the long end.
A new circuit of Modular Multilevel Inverter for grid-connected photovoltaic conversion plants

This study presents a new circuit topology of the Modular Multilevel Converter (MMC) which is deployed for photovoltaic grid applications. In the conventional MMC, two arm inductors are placed in each phase to limit the circulating current. In the proposed topology, the inductors are replaced by a transformer. The proposed circuit gives a 50% reduction of the voltage rating of the power devices and the capacitors in comparison with the conventional MMC. The required dc-link voltage which is fed directly by PV panels is also reduced by half. The paper presents a PWM method to control the solar inverter output voltage. The proposed concept is confirmed through simulation and experimental results.
Are Serum to Dialysate Sodium Gradient and Segmental Bioimpedance Volumes associated with the Fall in Blood Pressure with Hemodialysis?

Introduction A fall in blood pressure is the most common complication of outpatient hemodialysis. Several factors have been implicated, including serum sodium to dialysate gradient, ultrafiltration rate, and the amount of fluid to be removed during dialysis. Methods We prospectively audited 400 adult patients attending for their routine midweek hemodialysis session, and recorded changes in mean arterial blood pressure (MAP). Results Mean age 58.4 ± 16.6 years, 60.9% male, 30.7% diabetic, 36.8% Caucasoid, single pool Kt/V 1.57 ± 0.4, and median percentage change in MAP −6.7% (-14.1 to + 2.8). The percentage fall in MAP was greatest for those starting with higher MAPs (β 0.448, F 67.5, p<0.001), greater serum sodium to dialysate sodium gradient (β 0.676, F 5.59, p = 0.019), and age (β 0.163, F 5.15, p = 0.024). In addition, the percentage fall in MAP was greater in those with the lowest segmental extracellular water/total body water (ECW/TBW) ratios in the right arm prior to dialysis (β −477.5, F 7.11, p = 0.008). Conclusions Falls in blood pressure are common during dialysis, and greater for those starting dialysis with the highest systolic pressures, greater dialysate to serum sodium concentration gradient, and also those with the least ECW in the arm. As such, segmental bioimpedance may be useful in highlighting patients at greatest risk for a fall in blood pressure with dialysis.
Using population genetic methods to identify the origin of an invasive population and to diagnose cryptic subspecies of Telchin licus (Lepidoptera: Castniidae)

Abstract Telchin licus, the giant sugarcane borer, is an important pest species of sugarcane in northeast Brazil. Four subspecies of Telchin licus are recognized in Brazil based on their geographic distribution and subtle differences in wing colour pattern. Some taxa are morphologically indistinguishable, and their accurate identification is key to their efficient control. Mitochondrial genes sequences (cytochrome oxidase I and subunit 6 of the nicotinamide adenine dinucleotide dehydrogenase) were applied to delimit taxonomic entities of T. licus, and to infer the origin of a newly established population in the state of São Paulo. The molecular data indicated that specimens sampled at different regions in Brazil are morphologically cryptic but genetically isolated entities, and at least three subspecies were assigned to the sampled localities. These data also suggested that the population collected from the state of São Paulo must have a common origin with populations from northeast Brazil, which corroborate the hypothesis that ornamental plants infested with larvae of T. licus might have been transported from the northeast to the southeast regions.
Faecal shedding and intestinal colonization of Salmonella enterica in in-bred chickens: the effect of host-genetic background

Considerable and reproducible differences were observed in the amount and duration of faecal excretion when in-bred lines of chickens were infected orally with S. enterica serovar Typhimurium at 6 weeks of age after being given a gut flora preparation when newly hatched. Similar but less pronounced results were observed with S. Enteritidis or S. Infantis. Differences in the viable numbers of the inoculated bacteria in caecal contents were detectable within 24 h of inoculation. No major differences were seen in Salmonella-specific serum IgA or IgG titres. Small differences were seen in the numbers of circulating heterophilic cells. Caecal contents taken from the more resistant lines immediately prior to challenge appeared to be no more inhibitory for Salmonella in vivo than contents taken from susceptible lines. The more resistant lines showed a slightly higher rate of intestinal flow, as indicated by the rate of production of faecal droppings, although there was no difference in the rate of emptying of the caeca. In an F1 generation resistance was dominant and not sex-linked. There was no MHC linkage or any association with SAL1, the gene implicated in resistance to systemic salmonellosis in chickens, or NRAMP1.