Miracle-dz/UniFAR-FTUs huggingface dataset:
Kupffer cell–derived cytokines induce the synthesis of a leukocyte chemotactic peptide, interleukin‐8, in human hepatoma and primary hepatocyte cultures

Communication circuits operating between activated monocytes/macrophages and adjacent hepatocytes in the liver effect important alterations in hepatocyte function. We demonstrate here that primary human hepatocytes and hepatoma cells are able to function as effector cells in the recruitment of inflammatory cells in hepatic disease and inflammatory states by synthesizing a neutrophil/lymphocyte chemotactic factor, interleukin‐8. We have further investigated the possibility that endogenous factors elaborated by activated peripheral blood monocytes and Kupffer cells in the liver are mediators of hepatocytederived interleukin‐8 expression. Twenty‐four‐hour conditioned medium from lipopolysaccharidestimulated peripheral blood monocytes and nonparenchymal human liver cells enriched for Kupffer cells induced a time‐dependent increase in interleukin‐8 messenger RNA levels in SK‐hepatoma cells over a 24‐hr period, similar to that seen for tumor necrosis factor‐α or interleukin‐1β induction of interleukin‐8 in primary hepatocytes. Exogenously added lipopolysaccharide or recombinant interleukin‐6 had no effect. Cell‐associated interleukin‐8 antigen was present in SK‐hepatoma and primary hepatocytes that had been incubated with macrophage‐conditioned medium, tumor necrosis factor or interleukin‐1β. Similarly, neutrophil chemotactic activity was secreted by SKhepatoma cells, a significant proportion of which could be blocked with interleukin‐8–specific antiserum. Preincubation of macrophage‐conditioned medium with neutralizing antibodies to tumor necrosis factor‐α or interleukin‐1β reduced its interleukin‐8 messenger RNA‐inducing capacity. Exposure of SK‐hepatoma to conditioned medium followed by removal of the stimulus resulted in a rapid down‐regulation of interleukin‐8 messenger RNA to 50% of the maximum level within the first hour. These data suggest that products derived from activated Kupffer cells can modulate hepatoma cells and primary hepatocyte interleukin‐8 gene expression. In addition, macrophage/monocyte‐derived tumor necrosis factor‐α and interleukin‐1β have major roles in the positive regulatory component of this modulation. (HEPATOLOGY 1992;15:1112–1122.)
Automated Functional Size Estimation Using Business Process Models with UPROM Method

Estimating functional size in early phases of software projects is essential for accurate effort and cost planning. When an organization requires its business processes to be automated by a business application software, business processes are analyzed in the initial phases and utilized in various ways through software development life cycle. In previous studies we presented a unified business process modelling methodology, UPROM for the practices of business process and user requirements analysis, COSMIC based functional size estimation (FSE) and process documentation. Applying UPROM notation, process and guidelines to implement these practices in an integrated way, a set of models are developed that can be used to generate related artifacts. As one of the artifacts, UPROM tool is used to automatically estimate the early COSMIC functional size conforming to UPROM FSE method. The procedures and rules of UPROM FSE method are described in this paper. The results of multiple case study and validation activities indicate that UPROM can be used to achieve reasonably accurate size estimation results in early phases and decreased subjectivity without significant extra work for estimation.
Reducing and Filtering Point Clouds With Enhanced Vector Quantization

Modern scanners are able to deliver huge quantities of three-dimensional (3-D) data points sampled on an object's surface, in a short time. These data have to be filtered and their cardinality reduced to come up with a mesh manageable at interactive rates. We introduce here a novel procedure to accomplish these two tasks, which is based on an optimized version of soft vector quantization (VQ). The resulting technique has been termed enhanced vector quantization (EVQ) since it introduces several improvements with respect to the classical soft VQ approaches. These are based on computationally expensive iterative optimization; local computation is introduced here, by means of an adequate partitioning of the data space called hyperbox (HB), to reduce the computational time so as to be linear in the number of data points N, saving more than 80% of time in real applications. Moreover, the algorithm can be fully parallelized, thus leading to an implementation that is sublinear in N. The voxel side and the other parameters are automatically determined from data distribution on the basis of the Zador's criterion. This makes the algorithm completely automatic. Because the only parameter to be specified is the compression rate, the procedure is suitable even for nontrained users. Results obtained in reconstructing faces of both humans and puppets as well as artifacts from point clouds publicly available on the web are reported and discussed, in comparison with other methods available in the literature. EVQ has been conceived as a general procedure, suited for VQ applications with large data sets whose data space has relatively low dimensionality
A Reinforced Approach for Enhancing Stochastic Search

Stochastic search algorithms are often robust, scalable problem solvers. In this paper, we carefully study the Iterative Sampling(IS), Heuristic-Biased Stochastic Sampling(HBSS) and Value-Biased Stochastic Sampling(VBSS) algorithm, and present an approach for enhancing such multi-start algorithms. This paper shows that given some heuristic information about the search start point, these algorithms would achieve a higher level of performance. Historical information can be reused as heuristic information which provides a start node in the search tree. And further, we extend this approach in such a way that a solution is cut off into pieces and the stochastic algorithm produces one piece in every phase of the reinforced approach. Finally, we apply this approach to the HBSS and VBSS, and use them to solve the weighted tardiness scheduling with sequence-dependent setups problem to evaluate this approach. The results of these experiments are positive.
On the use of quality measures for text-independent speaker recognition

The use of quality information on automatic recognition systems is studied. From an apparent definition of what constitutes a quality measure, a framework for the successful exploitation of the quality information is derived. Potential applications are also introduced at different phases of the recognition process, namely: enrollment, scoring and multi-level fusion stages. Traditional likelihood scoring stage is further developed providing guidelines for the practical application of the proposed ideas. Preliminary experiments corroborate the benefits of the proposed quality-guided recognition approach. In particular, a frame-level quality measure meeting a goodness criterion based on deviation from the fundamental frequency is used, obtaining encouraging initial results.
A Novel Methodology for Stock Investment Using Episode Mining and Technical Indicators

This paper proposes a novel methodology for stock investing using the technique of episode mining and technical indicators. The time-series data of stock price is used for the construction of complex episode events and rules. Our experimental results show that the episode rule mining method not only improves a well-known technical indicator alone, but also assists it in outperforming the benchmark. Based upon the results obtained, we expect this episode mining methodology to advance the research in data mining for finance, and provide an alternative strategy to stock investment in practice.
A multi-resolution filter bank and fuzzy logic based channel edge detector for military wideband radio receivers

In a typical multi-standard military radio receiver, the radio channels (frequency bands) of interest have time varying bandwidth and locations in the wideband signal. Thus the receiver needs to detect the desired channels from the wideband input signal, which involves determining bandwidths of the channels and their locations (center frequencies) within the wideband signal. In this paper we propose a multi-resolution filter bank based spectrum sensor and a fuzzy logic based algorithm for channel edge detection in the wideband signal. For the same sensing resolution, the proposed edge detector has low complexity compared to other methods available in literature. The error in channel edge detection is reduced using fuzzy logic based algorithm. Simulation results show that our method offers an average channel edge detection accuracy of 99%.
Parameterization Using Manifolds

There are a variety of surface types (such as meshes and implicit surfaces) that lack a natural parameterization. We believe that manifolds are a natural method for representing parameterizations because of their ability to handle arbitrary topology and represent smooth surfaces. Manifolds provide a formal mechanism for creating local, overlapping parameterization and defining the functions that map between them. In this paper we present specific manifolds for several genus types (sphere, plane, n-holed tori, and cylinder) and an algorithm for establishing a bijective function between an input mesh and the manifold of the appropriate genus. This bijective function is used to define a smooth embedding of the manifold that approximates or interpolates the mesh. The smooth embedding is used to calculate analytical quantities, such as curvature and area, which can then be mapped back to the mesh. Possible applications include texture mapping, surface fitting, arbitrary topology surface modeling, feature detection, and surface comparison.
Literature review of brain computer interface (BCI) using Electroencephalogram signal

The system based on brain computer interface has been developed from past 30 years and now grown into the vast and diverse field. The first brain activity signal is recorded by Berger in year 1942. The electrical signal which are generated by brain activity is also known as Electroencephalogram (EEG). The system which depends on Electroencephalogramshould capable to provide more controlled variable commands to the user. The control capability of this signal have been depend on the electrodes and the noise reduction technique used for preparing the system. Now a days the electrodes are getting better and have very large range of selection criteria depends on application such as the gel based electrodes are used to obtain the high sensitivity for better resolution. Recently various sensors (electrodes) are introduced for producing high quality brain signal with less distortion compareto gel based electrodes. The signal acquisition system are also getting better by using the op-amp based filter circuits and composite instrumentation amplifier integrated circuit. The aim of BCI is to control the robotics machinery with better accuracy. The main use of BCI is to control the wheelchair or robotic limb movement for the disable person and can be used to accessing security system. The BCI can be used to discover the emotions which is also use to control the surrounding environment such as controlling the interior of the car or house.
Entity Hierarchy Construction for Repair Request Records

A repair request record is an unstructured short text written by customers to describe quality problems of building products. The extraction of entities and the construction of a hierarchical structure can provide an efficient source of knowledge for business decision and quality supervision. Firstly, based on the syntactic dependency and the lexical semantic information of repair request records, an approach combined the double propagation algorithm and the defect entity domain relevance is applied on repair request records to achieve entity extraction. Then, a graph-based hierarchy construction method is used to organize the extracted entities into a hierarchical structure. We further introduce the defect entity peer confidence to handle the task of graph pruning. Experiment results show that our methods can construct the hierarchy effectively and achieve better precision and recall compared to existing methods.
Touch the map!: designing interactive maps for visually impaired people

Visually impaired people face important challenges related to orientation and mobility. Accessible geographic maps are helpful for travel preparation. Historically, raised-line paper maps have been used, but these maps possess significant limitations. However, recent technological advances have enabled the design of accessible interactive maps that overcome these limitations. This paper presents the development of an accessible interactive map prototype based on the cycle of participatory design. Development steps are presented for each phase in the cycle: the analysis of context and users' needs, generation of design ideas, prototyping and the evaluation of the prototype with visually impaired users. Our studies confirm a high usability and, thus, importance of these map types to the visually impaired.
Prospects for top-prime quark discovery at the Tevatron

We show that a top-prime quark as heavy as 600 GeV can be discovered at the Tevatron, provided it is resonantly pair-produced via a vector color octet. If the top-prime originates from a vectorlike quark, then the production of a single top-prime in association with a top may also be observable, even through its decay into a Higgs boson and a top. A color octet with mass of about 1 TeV, which decays into a top-prime pair, may account for the CDF excess of semileptonic (Wj)(Wj) events.
The Transversality of Michel de Certeau: Foucault's Panoptic Discourse and the Cartographic Impulse

Above all (and this is a corollary, but an important one), the phenomenological and praxiological analysis of cultural trajectories must allow to be grasped at once a composition of places and the innovation that modifies it by dint of moving and cutting across them. -Michel de Certeau, Culture in the Plural Through his rigorous examinations of the common, the quotidian, the personal, the plural practices that establish and continually transform societies, Michel de Certeau develops a conception of culture born of the perpetual transgression, however subtle or pronounced, of the boundaries imposed by all totalizing systems, whether theoretical or social. This view of culture as a "cutting across" of boundaries, which can be found in many forms throughout his work, achieves a special significance for the study of subjectification in his discussion of "Spatial Practices" that comprises the third section of The Practice of Everyday Life. In an important essay on Certeau's theory of space, Ian Buchanan argues that "our understanding of culture must commence with an understanding of the formation of the subject," and that the latter is addressed by Certeau through his essays on space [129-30]. Following this assertion, we want to argue that Certeau's analyses of spatial practices in Heterologies, "The Gaze: Nicholas of Cusa," and The Practice of Everyday Life [particularly the chapter "Walking in the City" 91110], outline a theory that describes subjectivity as what amounts to, as Certeau puts it in Culture in the Plural, "a composition of places and the innovation that modifies it by dint of moving and cutting across them" [146]. Furthermore, by articulating the close relationship between Certeau's spatial theory and our own work on "transversal movement," we will attempt to show that the method of analysis Certeau uses in "Walking in the City" (and describes in several other works) is itself marked by the "transversal" tactics that his theory describes. ' By focusing in particular on Certeau's methodological critique of Foucault in both The Practice of Everyday Life and Heterologies, we will demonstrate the various ways in which he moves beyond what Bryan Reynolds and James Intriligator have labeled the "dissective-cohesive mode" of analysis, an analyti1. The terms "transversal" and "transversality" are used throughout this essay in the sense that Bryan Reynolds gives them in his article "The Devil's House, 'or worse': Transversal Power and Antitheatrical Discourse in Early Modern England. " Reynolds's source for the terms, as noted in that article [148n16], is Felix Guattari's discussion of group desire in the essays collected in Molecular Revolution: Psychiatry and Politics. Reynolds explains that in appropriating Guattari's term he also "extend[s] [Guattari's] definition of transversality to conceptuality and its territories and allow[s] it to apply to the existential processes of individuals as well as of groups. "
Sufficient Sample Size and Power in Multilevel Ordinal Logistic Regression Models

For most of the time, biomedical researchers have been dealing with ordinal outcome variable in multilevel models where patients are nested in doctors. We can justifiably apply multilevel cumulative logit model, where the outcome variable represents the mild, severe, and extremely severe intensity of diseases like malaria and typhoid in the form of ordered categories. Based on our simulation conditions, Maximum Likelihood (ML) method is better than Penalized Quasilikelihood (PQL) method in three-category ordinal outcome variable. PQL method, however, performs equally well as ML method where five-category ordinal outcome variable is used. Further, to achieve power more than 0.80, at least 50 groups are required for both ML and PQL methods of estimation. It may be pointed out that, for five-category ordinal response variable model, the power of PQL method is slightly higher than the power of ML method.
CUBOD: a customized body gesture design tool for end users

As motion sensors have become more advanced, gesture-control systems have become more popular in gaming and everyday appliances. However, in existing systems, gestures are predefined by designers or pattern-recognition experts. Such predefined gestures can be inconvenient for specific users in specific environments. Hence, it would be useful to provide end users the flexibility to design and customize gestures to satisfy their own needs. In this paper, we present a system that allows end users to design and customize gestures interactively. A key challenge is that arbitrary user-defined gestures can be difficult for the computer to recognize reliably. A gesture may be too similar to frequent unintentional moves, too difficult to distinguish from other gestures, and/or too difficult to perform consistently. Hence, our system first evaluates the user-defined gesture and then gives feedback on its appropriateness to guide the user in the design of appropriate gestures. A user study demonstrated that users were able to design more appropriate gestures with such guidance than without it.
A dynamic simulation and virtual evolution platform for modular self-reconfigurable robots

Simulation platform can be used to significantly reduce research price, develop and validate algorithms. In case of locomotion evolution, we must refer to simulation platform to quickly find solutions. Modular self-reconfigurable robots comprise of modules with identical functions and have various configurations. It is hard to plan an arbitrary configuration for its redundant freedom setup. Thus execute locomotion evolution in a dynamic simulator is preferred. Some researchers have developed their own dynamic simulator with certain purpose. To realize UBot self-reconfigurable robot's dynamic simulation and virtual evolution, we developed an efficient dynamic simulator with the ability of creating arbitrary configuration and fully exerting computer's computing power. This paper presents the simulator and lists some methods to enhance dynamic simulation efficiency which can be used in other simulator research.
Connecting Temporary and Permanent Organizing: Tensions and Boundary Work in Sequential Film Projects

This paper investigates the relationship between a permanent organization and a series of temporary organizations. It draws on an in-depth study of the process through which a Danish film production company, seeking to balance innovation and persistence in a troubled industry, struggles to realize a novel children’s film and its sequels. The study reveals tensions at different levels as well as boundary work and boundary roles that address them, bringing in shadows of past and future projects. The study extends the understanding of the dialectic between temporary and permanent organizing by emphasizing how ongoing work at different boundaries affects the permanent and temporary organizing’s connectedness and outcomes. It also challenges the overly bracketed view of temporary organizations, suggesting a temporality perspective on temporariness.
Coronal joint spaces of the Temporomandibular joint: Systematic review and meta-analysis

Introduction The joint space measurements of the temporomandibular joint have been used to determine the condyle position variation. Therefore, the aim of this study is to perform a systematic review and meta-analysis on the coronal joint spaces measurements of the temporomandibular joint. Material and Methods An electronic database search was performed with the terms “condylar position”; “joint space”AND”TMJ”. Inclusionary criteria included: tomographic 3D imaging of the TMJ, presentation of at least two joint space measurements on the coronal plane. Exclusionary criteria were: mandibular fractures, animal studies, surgery, presence of genetic or chronic diseases, case reports, opinion or debate articles or unpublished material. The risk of bias of each study was judged as high, moderate or low according to the “Cochrane risk of bias tool”. The values used in the meta-analysis were the medial, superior and lateral joint space measurements and their differences between the right and left joint. Results From the initial search 2706 articles were retrieved. After excluding the duplicates and all the studies that did not match the eligibility criteria 4 articles classified for final review. All the retrieved articles were judged as low level of evidence. All of the reviewed studies were included in the meta-analysis concluding that the mean coronal joint space values were: medial joint space 2.94 mm, superior 2.55 mm and lateral 2.16 mm. Conclusions the analysis also showed high levels of heterogeneity. Right and left comparison did not show statistically significant differences. Key words:Temporomandibular joint, systematic review, meta-analysis.
THE EFFECTS OF ORGANIC CHEMISTRY ANXIETY ON UNDERGRADUATE STUDENTS IN RELATION TO CHEMISTRY ATTITUDE AND ORGANIC CHEMISTRY ACHIEVEMENT

The aim of this study was to investigate the effects of organic chemistry anxiety on sophomore undergraduate students in relation to chemistry attitude and organic chemistry achievement. The participants were 228 sophomore undergraduate students, enrolled in organic chemistry courses. Anxiety and attitude were measured using O-CAS and CAS, respectively. O-CA was measured by determining a point total for each student, using the results of exams and quizzes from organic chemistry courses. The results of an ANOVA showed a significant difference in the means for O-CA and chemistry attitudes scores between the low, moderate, and high anxiety groups. The findings also revealed a moderate, significant negative correlation between organic chemistry anxiety and achievement, and a small, significant negative correlation between organic chemistry anxiety and chemistry attitudes. In addition, there was a small, significant positive correlation between chemistry attitudes and organic chemistry achievement. Key words: achievement, chemistry attitude, organic chemistry anxiety, undergraduate students.