Miracle-dz/UniFAR-FTUs huggingface dataset:
Opening new pathways for innovation in healthcare

ABSTRACT Is open innovation an appropriate strategy to promote innovation through Public Health Research Institutes (PHRIs) in developing countries? The goal of this article is to evaluate the effectiveness of the strategy. PHRIs in developing countries confront a variety of problems, from the need to adapt to the speed of technological innovation to insufficient technical teams and inadequate capacity caused by budget cuts and bureaucratic constraints. The article presents a case study of an open innovation initiative in a Brazilian PHRI as a strategic approach to catalyze innovation processes. This action research showed that the open innovation approach benefits innovation processes in public health in a developing country. However, if practices are merely transposed from successes in the entrepreneurial sector, for which it was originally conceived, there is significant risk of rejection from the metaphorical ‘antibodies’ in PHRIs. The open innovation approach should be treated as a continuous, rather than discrete, solution when dealing with public sector attempts to engage in innovation. The article presents aspects that need special care in order to exploit the potential for open innovation and mitigate the risk of rejection.
Kobuviruses – a comprehensive review

Kobuviruses are members of the large and growing family Picornaviridae. Until now, two official, Aichi virus and Bovine kobuvirus, and one candidate kobuvirus species, ‘porcine kobuvirus’, have been identified in human, cattle and swine, respectively. In addition, kobu‐like viruses were detected very recently in the bat. Aichi virus could be one of the causative agents of gastroenteritis in humans, and kobuviruses probably also cause diarrhoea in cattle and swine. Although Aichi virus has been detected relatively infrequently (0–3%) in human diarrhoea, high seroprevalence, up to 80–95% at the age of 30–40, was found indicating the general nature of infection in different human populations. In the previous years, much new information has accumulated relating to kobuviruses and their host species. This review summarises the current knowledge on kobuviruses including taxonomy, biology and viral characteristics, and covers all aspects of infection including epidemiology, clinical picture, host species diversity, laboratory diagnosis and it gives a summary about possible future perspectives. Copyright © 2011 John Wiley & Sons, Ltd.
Financial Ecological Environment, Ownership Structure and the Financing Efficiency of New Energy Industry in China

Financing efficiency is reflected in the ability of enterprises to integrate funds with the lowest cost and risk, and to use the integration of funds for bring the highest profits to the company in a specific macro environment. Its effective promotion cannot be separated from the external financial ecological environment and internal governance foundation. Take the sample of 132 listed companies of China’s new energy industry from 2010 to 2016, then use a generalized DEA model which is based on panel data to measure its dynamic financing efficiency, and construct a systematic GMM model to empirically examine the impact of financial ecological environment and ownership structure on the financing efficiency of new energy industry, the research shows that the financing efficiency of new energy industry has obvious inertial effect and time cumulative effect, and it has entered a steady upward track, while there is still much room for improvement. The economic foundation and the level of financial resources are positively related to the financing efficiency of new energy industry. The influence of the legal honest environment and humanistic social environment on the financing efficiency of new energy industry is not yet obvious. The non-state-owned new energy listed companies with relatively dispersed equity in the eastern and central regions have higher financing efficiency, and the state-owned new energy listed companies with relatively concentrated equity in the western region have higher financing efficiency. It is necessary to further improve the benign development mechanism of capital financing and scientific allocation of new energy industry in allusion to the differences of the financial ecological environment and ownership structure of enterprises in different regions. Keywords—financial ecological environment; ownership structure; financing efficiency; new energy industry
Methodes d'analyse arboree. Algorithmes. Applications

La these porte sur l'usage des arbres non hierarchiques pour representer, analyser et interpreter les donnees. L'expose aborde les principaux themes suivants: les arbres en tant que famille des parties (ou hypergraphe), l'association d'une arbre et d'une relation quaternaire, l'aspect topologique des arbres, les algorithmes de representation arboree, et les applications a des donnees textuelles. Cette etude mathematique et algorithmique des arbres debouche en particulier sur une famille de methodes derivees de la notion de groupement: algorithmes de representation arboree des mesures de dissimilarites, de donnees manquantes, de hierarchisation, de consensus et de representation de donnees non metriques
RENAL DISEASE IN SYSTEMIC LUPUS ERYTHEMATOSUS.

THE ability of adrenal corticosteroid therapy to prolong life in patients with systemic lupus erythematosus has been recognized by most observers.1 2 3 It is generally stated, however, that the renal lesion usually progresses despite suppression of activity of the disease in other systems.1 2 3 Recently, Pollak et al.4 have suggested that "lupus glomerulonephritis" can be treated successfully by prolonged administration of corticosteroids if they are given in excess of the dosage required to control other manifestations of the disease. We have observed a relatively low incidence of progressive renal disease in patients with systemic lupus erythematosus although steroids have been administered at .
The Biochemistry of Green Tea Polyphenols and Their Potential Application in Human Skin Cancer

Green tea contains many polyphenol substances with exceptional antioxidant activity, and is consumed widely throughout the world. Green tea aqueous extract and its polyphenols, of which epigallocatechin gallate (EGCG) predominates, have been studied extensively in animal models for their anti-neoplastic properties. EGCG and green tea polyphenols (GTP) have been shown to inhibit skin tumor initiation, promotion, and progression by a number of mechanisms, including, but not limited to: inhibition of DNA binding by carcinogens, radical scavenging, inhibition of cytochrome P-450, maintenance of cellular communication, and inhibition of arachidonic acid metabolism. It is evident that the consumption of green tea is beneficial in the prevention of cancer in these models; however, the question remains whether use of oral or topical green tea preparations will have a preventative effect on human skin cancers, and should be answered by well-designed human clinical and epidemiological studies. (Alt Med Rev 1996;1:31-42.)
Ultra-wideband microstrip patch antenna design using a modified partial ground plane

In this article, the design of an ultra-wideband (UWB) microstrip patch antenna is presented, analyzed and manufactured. The antenna consists of modified circular-shaped patch antenna and semicircular finite ground plane. The UWB is achieved by introducing a staircase shaped slot to the radiating element and a rectangular slot to the ground plane. The proposed antenna has a small size of 23×28 mm2 and operates over the frequency band between 3.0–14.6 GHz.
TEMPOS : une plate-forme pour le développement d'applications temporelles au dessus de SGBD à objets

Les donnees temporelles sont presentes dans de nombreuses applications utilisant des Systemes de Gestion de Bases de Donnees (SGBD). Aussi, la plupart de ces systemes offrent des types correspondant aux concepts de date et de duree, grâce auxquels il est possible de modeliser des associations temporelles simples, comme par exemple la date de naissance ou l'âge d'une personne. Toutefois, a quelques nuances pres, aucun de ces systemes n'offre des abstractions dediees a la modelisation d'associations temporelles plus complexes, telles que l'historique du salaire d'un employe, ou la sequence d'annotations attachees a une video. Des lors, ces associations doivent etre codees au travers de constructeurs de type tels que ''liste'' et ''n-uplet'', et la semantique de ce codage doit etre integree dans la logique des programmes applicatifs, accroissant par la leur complexite. Pour combler ces lacunes, des extensions dites ''temporelles'' de modeles et de langages pour Bases de Donnees ont ete proposees. Cette these analyse et unifie les contributions de ces travaux, dans le but de les integrer dans une extension temporelle du standard pour SGBD a objets de l'ODMG. Le resultat est une plate-forme logicielle baptisee TEMPOS, fondee sur trois modeles de sophistication croissante : un modele du temps, un modele d'historiques et un modele d'objets et de proprietes temporels. Ce dernier fournit des fonctionnalites facilitant la transformation de bases de donnees conformes a l'ODMG en des bases de donnees temporelles. a partir de ces trois modeles, des extensions des langages de specification de schema et d'interrogation de l'ODMG sont definies. Enfin, un outil de visualisation base sur un nouveau paradigme de navigation interactive au travers d'objets temporels est developpe. L'ensemble des propositions sont formalisees, implantees au dessus d'un SGBD commercial, et validees par des etudes de cas.
Factoral Analysis of the Financial Leverage of the Enterprise

The activities of the enterprises always involve some uncertainty, therefore there is always a risk that objectives may not be achieved. So, theoretical and practical aspects of business risks are always relevant. The goal of the research is to select the general indicator of the financial risk between the leverage coefficients of the enterprises and to create its’ factorial model. The subject of research is the system of financial leverage ratios of the enterprise. Financial information on Georgian wine companies is used for the practical provision for research. As a result of the research has been created a new factor model of the general indicator of financial leverage. It is possible to measure five-factor indicators making an impact on the level of financial leverage. Its regular analysis will help enterprise management to fully control and manage the financial risks of the enterprise, to implement adequate measures on the basis of which the financial stability of the enterprise would not be jeopardized, which is also in the public interest.
Refined Multidisciplinary Protocol-Based Approach to Short Bowel Syndrome Improves Outcomes

Objective: Management of short bowel syndrome (SBS) has significantly evolved recently. We present our single-center, 25-year experience focusing on the implementation of a refined multidisciplinary SBS care protocol. Methods: This is a retrospective review of the patients with SBS treated at our tertiary center from 1988 to 2014, with either <25% short bowel remaining or duration of parenteral nutrition (PN) >3 months. Patients with primary intestinal motility disorders were excluded. Clinical characteristics, including intestinal anatomy, markers of cholestasis, and catheter-related infections (CRIs), were analyzed. The implementation of a refined modern uniform management protocol in 2009 divided the cohort into 2 subgroups, whose outcomes are compared. Results: Forty-eight patients with SBS were identified (median gestational age 33 weeks). Of them, 22 were born between 2009 and 2014. The main causes of SBS were necrotizing enterocolitis (46%) and midgut volvulus (23%). Median remaining small bowel length was 36 cm. The overall survival was 23 of 26 (88%) before 2009 and 21 of 22 (95%) thereafter, whereas none were transplanted. Duration of PN shortened from a median of 15 to 6 months (P = 0.0015) in the latter cohort, whereas frequency of autologous intestinal reconstruction surgery (31%) remained unchanged. Frequency of neonatal cholestasis was similar in both groups (75%), but cleared in all after 2009. Before 2009, 2 patients died of progressive cholestatic liver failure. The CRI rates decreased from 1.7 to 0.7 per 1000 catheter-days between 2000–2008 and 2009–2014, respectively (P = 0.0178). Conclusions: Uniform refined multidisciplinary approach decreased the duration of PN and CRI rates with high transplant-free survival and avoidance of liver failure, although the frequency of transient neonatal cholestasis remained unchanged.
Attribute Prioritization in Discrete Choice Experiment: Challenges and Suggested Approach in a study on Malaysian Islamic Finance Talent Job Choice

There has been an increase use of Discrete Choice Experiment (DCE) by researchers in the field of Human resources management. DCE is a quantitative technique that quantifies values placed on non-market goods, services or policies through the analysis of choices made among a combination of attribute and attribute levels presented in hypothetical experiment questionnaires. Attributes are cogent in DCE studies; hence, the first step in DCE studies is the selection and prioritisation of attributes. There are calls for caution in this stage to ensure valid research outcomes, however, scanty attention has been given to this important stage. Even though researchers have adopted qualitative techniques in the prioritisation of attributes for DCE, these are fraught with weaknesses. Issues such as subjective bias of the researcher and lack of statistically efficient outcomes because of small sample use, have been reported. More so, contextual issues such as nationality and other differences in survey population has necessitated a need to employ a more rigorous approach in prioritisation of attribute in DCE. It is against this background that this study introduced relative importance index (RII) in graduate talents’ preference for job and organisation attributes in the Malaysian Islamic finance industry. Stratified sample was employed with the administration of 5point Likert scale questionnaire to investigate respondents’ preferences among 12 selected job and organisation attributes. The result of this study showed that all selected attributes had RII>0.5 and could all be added in the experimental design. This study could help researchers in mitigating identified challenges in qualitative methods. Keywords : Attribute prioritisation, Discrete Choice Experiment, Relative Importance Index, Talent job choice.
Effect of the early social environment on behavioural and genomic responses to a social challenge in a cooperatively breeding vertebrate

The early social environment can have substantial, lifelong effects on vertebrate social behaviour, which can be mediated by developmental plasticity of brain gene expression. Early‐life effects can influence immediate behavioural responses towards later‐life social challenges and can activate different gene expression responses. However, while genomic responses to social challenges have been reported frequently, how developmental experience influences the shape of these genomic reaction norms remains largely unexplored. We tested how manipulating the early social environment of juvenile cooperatively breeding cichlids, Neolamprologus pulcher, affects their behavioural and brain genomic responses when competing over a resource. Juveniles were reared either with or without a breeder pair and a helper. Fish reared with family members behaved more appropriately in the competition than when reared without. We investigated whether the different social rearing environments also affected the genomic responses to the social challenge. A set of candidate genes, coding for hormones and receptors influencing social behaviour, were measured in the telencephalon and hypothalamus. Social environment and social challenge both influenced gene expression of egr‐1 (early growth response 1) and gr1 (glucocorticoid receptor 1) in the telencephalon and of bdnf (brain‐derived neurotrophic factor) in the hypothalamus. A global analysis of the 11 expression patterns in the two brain areas showed that neurogenomic states diverged more strongly between intruder fish and control fish when they had been reared in a natural social setting. Our results show that same molecular pathways may be used differently in response to a social challenge depending on early‐life experiences.
Analysis of cylindrical stereo imaging

Conventional stereo imaging uses area CCDs for which depth perception error has been analyzed in our past research (Sahabi and Basu, 1996). In this work we analyze the depth perception error for a stereo system that uses two rotating linear CCD cameras to create cylindrical stereo images. Theoretical analysis shows certain advantages to cylindrical stereo imaging over conventional methods. Initial experimental results are presented to validate the theoretical results. Unlike normal area CCD cameras, rotating linear CCD cameras can capture very high resolution images thereby substantially reducing depth estimation error; more importantly, the error has certain directionally uniform characteristics.
Drawing of layout documentation as the basis of logistics management system of a company literature review, new methodics, case study

Contemporary business market environment has got very dynamic and volatile character. The financial and economy crisis in 2008 influenced all industrial branches and their supply chains in a great deal. Competitiveness across global markets is evident in many ways such as cost, quality or time delivery. The industrial companies must manage all processes in their inner and outer supply chains thru their integrated logistics management systems. General logistics management system of a company is composed of subsystems which can be classified as purchasing, manufacturing, warehousing, packaging, distribution and reverse material flows management. One of the logistics objectives is to plan, to manage and to control all rising material flows inside particular mentioned subsystems. Thus, the foundation of effective logistics management system is layout drawing documentation in required detail. The paper deals with very up-to-date topic, how and in which sequence to create layout drawing documentation of company's areas. The documentation should be created in given order and in appropriate detail level. For this purpose has been developed methodics which has been applied in an industrial sphere. According to the created methodics, the documentation should be included the layout drawings of industrial zone, production halls, production lines, production workshops, production cells and production workplaces, etc. As soon as the documentation is created in a company, the integrated logistics management system can start to be built and then all material processes can be effectively realized or optimized. The development of new methodics or methodologies is crucial for innovations today.
Visiads: A vision-based advertising platform for camera phones

In this demonstration, we present VisiAds, a vision-based online advertising platform which allows advertisers to bid on image content as opposed to text keywords. The demonstration shows an implementation of the platform designed specifically for mobile application scenarios. It can be used by advertisers to trigger and deliver multiple advertisements based on a query image captured from a consumer-grade cellular phone with an embedded camera.
Method and Approach Mapping of Fair and Balanced Risk and Value-added Distribution in Supply Chains: A Review and Future Agenda

This paper proposes a fair and balanced risk and value-added distribution as a novel approach for collaborative supply chain. The objective of this article is to analyze the existing methods and approaches for risk management, value-adding, risk and revenue sharing to develop a new framework for balancing risk and value-adding in collaborative supply chains. The authors reviewed and synthesized 162 scientific articles which were published between 2001 and 2017 and. The reviewed articles were categorized into supply chain management and performance, risk management, value-added, fair risk and value-added distribution and supply chain negotiation. The potentials identified for future research were the importance of decision-making and sustainability for effectiveness of supply chain risk management. Most previous authors have applied an approach of revenue –and risk-- sharing with both decentralized and centralized supply chains to achieve the fair risk and value-added distribution. The dominant methods we found in literature were game theory and complex mathematical formulation. Most literature focused on operation research techniques. We identified a lack of discussion of the intelligent system approach and a potential for future exploration. This paper guide future research and application agenda of fair risk and value-added distribution in supply chain collaboration. We developed a new framework for a fair and balanced risk and value-added distribution model. For a future agenda, we point towards the development of a systematic intelligent system applying soft-computing techniques and knowledge transfer for maintaining sustainable supply chains. Keywords — Supply chain collaboration, Fair risk and value-added distribution, Revenue sharing, Risk management, Risk sharing
Class II Radical Hysterectomy in Low-Risk IB Squamous Cell Carcinoma of Cervix: A Safe and Effective Option

Aim: The aim of this study was to determine the outcome of class II radical hysterectomy for the treatment of a subset of patients with early cervical cancer. Method: From September 1995 to September 2003, a total of 480 patients whose conditions were diagnosed with squamous carcinoma of the cervix with a tumor size of no greater than 2 cm and a pathological grade 1 to 2 was enrolled in a cohort study to compare class II and class III radical hysterectomy, with 240 patients in each group. Disease-free survival, overall survival, pattern of recurrences, and morbidity were the end points of observation for this study. Results: The class II surgery group had 100.0% overall and 98.33% disease-free actuarial 5-year survival rate, whereas the class III surgery group had 100.0% overall and 97.92% disease-free actuarial 5-year survival rate (P = 0.736). Recurrence rate (2.92% in class II vs 2.50% in class III) was not significantly different in the 2 groups (P = 0.779). The operating time, postoperative length of hospital stay, and estimated blood loss at surgery were significantly lower in the group of patients who underwent class II hysterectomy (P = 0.0001, P = 0.0001, and P = 0.001, respectively). The postoperative complications were also significantly lower in patients who received class II hysterectomy. Conclusions: In treating a subset of patients with tumor size no greater than 2 cm and grade 1 to 2 squamous cell cancer, class II and class III radical hysterectomy are equally effective, but the former has far less complications than the latter.