Miracle-dz/UniFAR-FTUs huggingface dataset:
Hubungan Umur, Jenis Kelamin, dan Hipertensi dengan Kejadian Stroke

Stroke adalah penyakit neurologi yang paling mengancam kehidupan. Di Indonesia, diperkirakan setiap tahun terdapat 500.000 penduduk yang terkena serangan stroke. risiko stroke meningkat seiring dengan berat dan banyaknya faktor risiko. Penelitian ini bertujuan untuk mengetahui hubungan antara umur, jenis kelamin dan hipertensi dengan kejadian stroke pada pasien yang dirawat inap di Rumah Sakit Umum Provinsi Sulawesi Tenggara tahun 2012. Penelitian ini bersifat deskriptif analitik dengan desain cross-sectional . besar sampel penelitian adalah 220 orang, yang diambil dengan menggunakan teknik systematic random sampling. Pengumpulan data diperoleh dari catatan rekam medik dan dianalisis dengan menggunakan uji statistic Chi-Square . dari hasil penelitian, ditemukan penderita stroke sebanyak 77 orang (35%) dan bukan stroke sebanyak 143 orang (65%). Kejadian stroke ditemukan paling banyak pada golongan umur > 55 tahun (67,5%), jenis kelamin laki-laki (52%) dan penderita hipertensi (88,3%). Dari hasil analisis bivariat, nampak bahwa variabel umur berhubungan dengan kejadian stroke (p=0,000) dan variabel jenis kelamin tidak berhubungan dengan kejadian stroke (p=0,308). Kesimpulan dari penelitian ini adalah terdapat hubungan antara umur dan hipertensi dengan kejadian stroke, sedangkan jenis kelamin tidak berhubungan dengan kejadian stroke. Kata Kunci: kejadian stroke, umur, jenis kelamin, hipertensi
The development of mobile internet technology acceptance model

Mobile internet refers to accessing wireless internet anytime and anywhere via mobile devices. Acceptance of mobile internet by individuals is critical to the successful implementation of mobile internet systems. Based on Unified Theory of Acceptance and Use of Technology (UTAUT) and many models in previous studies about mobile internet acceptance, the purpose of this study was to identify the determinants of mobile internet acceptance among university students in Bandung. Data collected from 271 undergraduate students in three private universities in Bandung (Indonesia) was tested against the research model using the Structural Equation Modeling (SEM) approach with LISREL 8.7 software. The results show that performance expectancy, social influence, facilitating condition, and perceived flexibility were significant determinants of behavioral intention to use mobile internet. The findings of this study provide several important implications for mobile internet services practitioners and researchers in Indonesia.
Time-Varying Harmonics: Part II-Harmonic Summation and Propagation

This paper represents the second part of a two-part article reviewing the state-of-the-art of probabilistic aspects of harmonics in electric power systems. It includes tools for calculating probabilities of rectangular and phasor components of individual as well as multiple harmonic sources. A procedure for determining the statistical distribution of voltages resulting from dispersed and random current sources is reviewed. Some applications of statistical representation of harmonics are also discussed.
MMM-classification of 3D range data

This paper presents a method for accurately segmenting and classifying 3D range data into particular object classes. Object classification of input images is necessary for applications including robot navigation and automation, in particular with respect to path planning. To achieve robust object classification, we propose the idea of an object feature which represents a distribution of neighboring points around a target point. In addition, rather than processing raw points, we reconstruct polygons from the point data, introducing connectivity to the points. With these ideas, we can refine the Markov Random Field (MRF) calculation with more relevant information with regards to determining “related points”. The algorithm was tested against five outdoor scenes and provided accurate classification even in the presence of many classes of interest.
Avoiding the pitfalls of case studies

C a s e studies have a wide variety of uses in ethics courses,from increasing ethical sensitivity to developing moral reasoning skills. This article focuses on ways to avoid 2 potential pitfalls of using typical case studies: lack of theoretical background and lackof suficient detail. Thefirst part explains how a personal ethics experience can be discussed as early as thefirst day of class in a way that sets the tone and expectations of an ethics course despite students' lack of exposure to ethical principles. Second, is an explanation of how a film can be used as an extended case that is rich enough in detail to sustain discussions about ethical theory over several weeks.
Replica Placement and Location using Distributed Hash Tables

Interest in distributed storage is fueled by demand for reliability and resilience combined with decreasing hardware costs. Peer-to-peer storage networks based on distributed hash tables are attractive for their efficient use of resources and resulting performance. The placement and subsequent efficient location of replicas in such systems remain open problems, especially (1) the requirement to update replicated content, (2) working in the absence of global information, and (3) determination of the locations in a dynamic system without introducing single points of failure. We present and evaluate a novel and versatile technique, replica enumeration, which allows for controlled replication and replica access. The possibility of enumerating and addressing individual replicas allows dynamic updates as well as superior performance without burdening the network with state information, yet taking advantage of locality information when available. We simulate, analyze, and prove properties of the system, and discuss some applications.
Asymmetric Mating Preferences Accommodated the Rapid Evolutionary Loss of a Sexual Signal

Rapid evolution has been well documented in naturally selected traits, but few examples exist for sexually selected traits, particularly sexual signals. This may in part be due to the complex set of behaviors associated with sexual signals. For a sexual signal to change, the change must be favorable for the signaler, but must also be accommodated by the receiver's perception and preferences. We investigated female accommodation of an extreme change in the sexual signal of Polynesian field crickets, Teleogryllus oceanicus. The cricket is native to Australia, widely distributed on Pacific Islands, and was recently introduced to Hawaii. Selective pressure by a deadly parasitoid fly favored a wing mutation in Hawaii (flatwing) that eliminates males' singing ability altogether Despite conventional wisdom that females require males to produce a courtship song before mating, we show that females from ancestral, unparasitized Australian and Pacific Island populations as well as parasitized Hawaiian populations, will mate with silent flatwing males, suggesting this behavioral option predates the change in sexual signal. Furthermore, ancestral Australian females discriminate against flatwing males more severely than island females. We suggest island colonization favored females with relaxed mating requirements (Kaneshiro's effect) facilitating the rapid evolutionary loss of song in Hawaii.
Impedance spectroscopy as a tool for non‐intrusive detection of extracellular mediators in microbial fuel cells

Endogenously produced, diffusible redox mediators can act as electron shuttles for bacterial respiration. Accordingly, the mediators also serve a critical role in microbial fuel cells (MFCs), as they assist extracellular electron transfer from the bacteria to the anode serving as the intermediate electron sink. Electrochemical impedance spectroscopy (EIS) may be a valuable tool for evaluating the role of mediators in an operating MFC. EIS offers distinct advantages over some conventional analytical methods for the investigation of MFC systems because EIS can elucidate the electrochemical properties of various charge transfer processes in the bio‐energetic pathway. Preliminary investigations of Shewanella oneidensis DSP10‐based MFCs revealved that even low quantities of extracellular mediators significantly influence the impedance behavior of MFCs. EIS results also suggested that for the model MFC studied, electron transfer from the mediator to the anode may be up to 15 times faster than the electron transfer from bacteria to the mediator. When a simple carbonate membrane separated the anode and cathode chambers, the extracellular mediators were also detected at the cathode, indicating diffusion from the anode under open circuit conditions. The findings demonstrated that EIS can be used as a tool to indicate presence of extracellular redox mediators produced by microorganisms and their participation in extracellular electron shuttling. Biotechnol. Bioeng. 2009; 104: 882–891. © 2009 Wiley Periodicals, Inc.
The Dialectics of Dystopia: Disorder and Zero Tolerance in The City

Dante, writing in the early years of the fourteenth century, was here referring to a real city, Cesena. His words demonstrate that the great Italian maestro had a keen eye for the peculiar ambivalence the city holds forth. That city, Cesena, Dante says, lives somewhere between tyranny and freedom. Being Dante, that somewhere always seemed to be on the edge of a deep and dark abyss. Even Florence, his beloved Florence — especially his beloved Florence — Dante’s home town, and from where he was banished forever, was portrayed in much the same light: ‘Be joyous, Florence’, he proclaims (1980: 239), ‘you are great indeed,/for over sea and land you beat your wings;/through every part of Hell your name extends! ’ With lines like these, Dante — whom Frederick Engels (1967: 75), in his preface to the 1893 Italian edition of The Communist Manifesto , saw as ‘the last poet of the Middle Ages and the first poet of modern time’ — sets the tone for some of the liveliest urban realism and criticism in our own day. His portrait of hell, of course, we now recognize as none other than the secular modern city. These days, many commentaries have intoned how modern cities such as New York, London and Los Angeles, express the best and worst that human civilization has to offer. In these cities, the literature says, we find joy and hope fighting it out with nihilism and despair. In these places, the ‘sighs and lamentations and loud cries’ that Dante (1980: 21) spoke about now transpire as dire poverty, homelessness and violent crime; and this coexists with enormous personal freedom and mobility (for both men and women), with dazzling stores stocked with every delight under the sun, with movie houses and theaters and restaurants and night clubs that suit practically every taste and fantasy. But there is another sense in which Dante’s urban visions are way ahead of their time: He was, for example, a precursor of an emergent species of writers, a species I shall call dystopian urbanists. Dystopian urbanists subvert received meanings of pain and pleasure in the city. Many emerge from differing disciplinary backgrounds, some hold differing political stances — though mostly they are on the Left; still more don’t recognize the paradoxes of their own analyses and wouldn’t admit to their dystopian credentials. And yet all, one way or another, graphically illustrate that there is a perverse allure to urban horror and pain and squalor. The ugly, the dangerous, the garish in city life can in fact be astonishingly titillating, a pleasure itself, a source of attraction, that simultaneously thrills and appalls, even while you sometimes hate yourself for being thrilled. Try as Mike Davis (1990) might to indict twentieth-century Los Angeles, the more he recounts its litany of horrors, the more we want to go there, and the more we, like Davis himself, are mesmerized and fascinated by its dynamics, by its perversity and absurdity.
Attentional selection of levels within hierarchically organized figures is mediated by object-files

Objects frequently have a hierarchical organization (tree-branch-leaf). How do we select the level to be attended? This has been explored with compound letters: a global letter built from local letters. One explanation, backed by much empirical support, is that attentional competition is biased toward certain spatial frequency (SF) bands across all locations and objects (a SF filter). This view assumes that the global and local letters are carried respectively by low and high SF bands, and that the bias can persist over time. Here we advocate a complementary view in which perception of hierarchical level is determined by how we represent letters in object-files. Although many properties bound to an object-file (i.e., position, color, even shape) can mutate without affecting its persistence over time, we posit that same object-file cannot be used to store information from different hierarchical levels. Thus, selection of level would be independent from locations but not from the way objects are represented at each moment. These views were contrasted via an attentional blink paradigm that presented letters within compound figures, but only one level at a time. Attending to two letters in rapid succession was easier if they were at the same-compared to different-levels, as predicted by both accounts. However, only the object-file account was able to explain why it was easier to report two targets on the same moving object compared to the same targets on distinct objects. The interference of different masks on target recognition was also easier to predict by the object-file account than by an SF filter. The methods introduced here allowed us to investigate attention to hierarchical levels and to object-files within the same empirical framework. The data suggests that SF information is used to structure the internal organization of object representations, a process understood best by integrating object-file theory with previous models of hierarchical perception.
The nasal delivery of nanoencapsulated statins – an approach for brain delivery

Purpose Along with their cholesterol-lowering effect, statins have shown a wide range of pleiotropic effects potentially beneficial to neurodegenerative diseases. However, such effects are extremely elusive via the conventional oral administration. The purpose of the present study was to prepare and characterize the physicochemical properties and the in vivo biodistribution of simvastatin-loaded lecithin/chitosan nanoparticles (SVT-LCNs) suitable for nasal administration in view of an improved delivery of the statins to the brain. Materials and methods Chitosan, lecithin, and different oil excipients were used to prepare nanocapsules loaded with simvastatin. Particle size distribution, surface charge, structure, simvastatin loading and release, and interaction with mucus of nanoparticles were determined. The nanoparticle nasal toxicity was evaluated in vitro using RPMI 2651 nasal cell lines. Finally, in vivo biodistribution was assessed by gamma scintigraphy via Tc99m labeling of the particles. Results Among the different types of nanoparticles produced, the SVT-LCN_MaiLab showed the most ideal physicochemical characteristics, with small diameter (200 nm), positive surface charge (+48 mV) and high encapsulation efficiency (EE; 98%). Size distribution was further confirmed by nanoparticle tracking analysis and electron microscopy. The particles showed a relatively fast release of simvastatin in vitro (35.6%±4.2% in 6 hours) in simulated nasal fluid. Blank nanoparticles did not show cytotoxicity, evidencing that the formulation is safe for nasal administration, while cytotoxicity of simvastatin-loaded nanoparticles (IC50) was found to be three times lower than the drug solution (9.92 vs 3.50 μM). In rats, a significantly higher radioactivity was evidenced in the brain after nasal delivery of simvastatin-loaded nanoparticles in comparison to the administration of a similar dose of simvastatin suspension. Conclusion The SVT-LCNs developed presented some of the most desirable characteristics for mucosal delivery, that is, small particle size, positive surface charge, long-term stability, high EE, and mucoadhesion. In addition, they displayed two exciting features: First was their biodegradability by enzymes present in the mucus layer, such as lysozyme. This indicates a new Trojan-horse strategy which may enhance drug release in the proximity of the nasal mucosa. Second was their ability to enhance the nose-to-brain transport as evidenced by preliminary gamma scintigraphy studies.
The dual role of fission yeast Tbc1/cofactor C orchestrates microtubule homeostasis in tubulin folding and acts as a GAP for GTPase Alp41/Arl2

Tbc1 is identified as the fission yeast orthologue of tubulin-folding cofactor C. In addition to its roles in tubulin folding, Tbc1 acts as a GAP in regulating the small GTPase Alp41/Arl2, which interacts with cofactor D Alp1. A model is given of the final stages of the tubulin cofactor pathway.
Modelos socioeconómicos para las pymes

En el presente articulo se revisan (5) modelos socioeconomicos para las Pequenas y Medianas Empresas (PYMES): formacion continua, asociatividad, desarrollo sostenible de empresas innovadoras, PYMES inteligentes y web fractal. Las ventajas y desventajas de dichos modelos se utilizaran para elaborar un nuevo modelo cuyo objetivo sera incrementar la productividad de las PYMES del sector manufacturero en el estado Lara. Entre los aportes mas importantes que los (5) modelos estudiados pueden hacer al modelo a proponer se encuentran: programas de capacitacion de personal, utilizacion del pensamiento complejo y borroso y espacios para la investigacion y desarrollo
Vibration Attenuation Timoshenko Beam Based on Optimal Placement Sensors/Actuators PZT Patches with LQR-MOPSO

The main objective of this study is to reduce optimal vibration suppression of Timoshenko beam under non-periodic step and impulse inputs. Cantilever beam was modeled by Timoshenko theory and finite element numerical method. Stiffness (K), mass (M), and damping (C) matrices are extracted. Then, in order to control structure vibration, piezoelectric patches were used due to simultaneous dual behavior, i.e. switching mechanical behavior to electrical behavior (sensor) and electrical behavior to mechanical behavior (actuator). Piezoelectric patches are used in two different arrays with equal dimensions and different elements for establishing feedback control. In the following, by using quadratic optimal controller (LQR), structure vibrations became attenuated. Weighting coefficients of R and Q matrices and piezoelectric patch location have been searched by multi-objective particle swarm optimization algorithm (MOPSO). Finally, the structure underwent standard inputs of impulse and step and the results are analyzed and compared.
Forensic Uses of Clinical Assessment Instruments

By Robert R. Archer, Elizabeth M. A. Wheeler. Second edition. New York: Routledge Taylor and Francis Group, 2013. 416 pages. $150.00 (hard cover), 84.95 (paperback). Familiar clinical measures evoke a sense of certainty. Forensic psychiatrists applying the results of such measures in forensic
Structural and biochemical characterization of the Clostridium perfringens autolysin catalytic domain

Bacterial autolysins can partially hydrolyze cell wall peptidoglycans into small sections to regulate cell separation/division and the growth phase. Clostridium perfringens autolysin (Acp) has an N‐terminal cell wall‐binding domain and a C‐terminal catalytic domain with glucosaminidase activity that belongs to the glycoside hydrolase 73 family. Here, we determined the X‐ray structure of the Acp catalytic domain (AcpCD) at 1.76 Å resolution. AcpCD has a unique crescent‐shaped structure, forming a deep groove for substrate‐binding at the center of the protein. The modeling study of the enzyme/substrate complex demonstrated that the length of the substrate‐binding groove is closely related to the glucosaminidase activity. Mutagenesis analysis showed that AcpCD likely adopts a neighboring‐group mechanism for the catalytic reaction.
Adverse events after infusions of cryopreserved hematopoietic stem cells depend on non-mononuclear cells in the infused suspension and patient age.

BACKGROUND Adverse events (AE) represent a significant clinical problem after infusion of cryopreserved HPC. However, the factors playing a role in the pathogenesis have not yet been fully established. METHODS We prospectively collected data on AE that occurred with 179 HPC infusions performed on patients affected with hematologic neoplasm after high-dose chemotherapy. The stem cell source was hemopoietic progenitor cells aphaeresis (HPC-A) in 157 cases and hemopoietic progenitor cell BM (HPC-BM) in 22 cases. In all cases, an endotoxin-free DMSO was used. RESULTS One or more AE were registered in 51/179 infusions (28.6%). The frequency of AE was higher after HPC-A than after HPC-BM (31.3% vs. 4.5%; chi(2) test, P =0.008). With univariate logistic regression, other factors found important for AE were age (P =0.028), number of total nucleated cells infused per kilogram (P =0.002), volume per kilogram infused (P =0.057), volume of packed RBC (P =0.019), a content of non-mononuclear cells >0.5 x 10(8)/kg (<P =0.0001) and actual time of infusion (P =0.058). When all aforementioned factors were evaluated with a multivariate logistic regression, only age of patient (P =0.024) and a content of non-mononuclear cells >0.5 x 10(8)/kg (P =0.0003) remained significant. A significant correlation existed between reduction of cardiac frequency both with volume per kilogram infused (r =0.221, P =0.02) and actual time of infusion (r =0.269, P =0.005). DISCUSSION Cardiovascular changes are influenced by volume per kilogram infused and by actual time of infusion, while non-cardiovascular AE are dependent on patient age and contamination by non-mononuclear cells in apheretic harvests.
Patient-provider Sex and Race/Ethnicity Concordance: A National Study of Healthcare and Outcomes

Background:Increasing patient-provider sex and race/ethnicity concordance has been proposed to improve healthcare and help mitigate health disparities, but the relationship between concordance and health outcomes remains unclear. Objective:To examine associations of patient-provider sex, race/ethnicity, and dual concordance with healthcare measures. Research Design and Participants:Analyses of data from adult respondents indicating a usual source of healthcare (N=22,440) in the 2002 to 2007 Medical Expenditure Panel Surveys (each a 2-year panel). Measures:Year 1 provider communication, sex-neutral (colorectal cancer screening, influenza vaccination) and sex-specific (mammography, Papanicolaou smear, prostate-specific antigen) prevention; and year 2 health status (SF-12). Analyses adjusted for patient sociodemographics and health variables, and healthcare provider (usual source of care) sex and race/ethnicity. Results:Of 24 concordance assessments, 3 were statistically significant. Women with female providers were more likely to report mammography adherence [average adjusted marginal effect=3.9%, 95% confidence interval (CI): 1.6%, 6.2%; P<0.01]. Respondents reporting dual concordance were less likely to rate provider communication in the highest quartile (average adjusted marginal effect =−4.2%, 95% CI: −8.1%, −0.2%; P=0.04), but dual concordance was associated with higher adjusted SF-12 Physical Component Summary scores (0.58 points, 95% CI: 0.00, 1.15; P=0.05). Conclusions:Little evidence of clinical benefit resulting from sex or race/ethnicity concordance was found. Greater matching of patients and providers by sex and race/ethnicity is unlikely to mitigate health disparities.