Miracle-dz/UniFAR-FTUs huggingface dataset:
DARK SIDE OF SOCIAL MEDIA; THE NEW DRUG FOR NEW GENERATION, ARE THEY ADDICTED?

Social media has become an increasingly important part of all cultures around the World. Twitter, Facebook, LinkedIn, Multiply and other social media sites have swept the nation and have come to dominate the millennial generation way of thinking and behaving. Social media allows interactive dialogue and social interaction with many people who in this day spend a lot of great deal online such as working, leisure, entertaining, and so on. Many cannot deny that using internet is helped to find the great deal of information and spend less time to do so. Until today there are still surprisingly few studies conducted on the subject matter of symptoms of Internet addiction and what can and cannot be classified as such, making this so called pathological sickness debatable. Many claimed that social media is merely a channel or medium that leads to other addictions. Therefore, many researchers have been working on the benefit of using internet. However, in this study the researcher searched for the negative part of using this tool as the dark side of technology. The study would be identified the issue of negative side of using it as well as factors that could be caused the addictive part. Using survey both online and in person had helped the researcher got more information in this part. Finding found amazing results even though it was insufficient to determine or prove the stated hypotheses. However the data collected can be useful when conducting further study on the online behaviors of undergraduates studying at one of the Private Universities. The fact that 70% of the samples are addicted which is an issue to be concerned, because being addicted to the internet means demonstrating a certain degree of psychological impacts, which can further leads to other issues.
IL-4 renders mast cells functionally responsive to endothelin-1.

It has previously been shown that mouse bone marrow-derived mast cells (BMMC) synthesize and secrete endothelin-1 (ET-1) and express ETA-type endothelin receptors (ETA-R). The study presented here was designed to elucidate the influence of different cytokine conditions for cellular differentiation and maturation on the ability of primary mouse BMMC to respond to exogenous ET-1. BMMC were grown for 2 wk in IL-3 alone and then cultured for 2 to 3 wk with kit ligand (KL) and/or IL-3 in the presence or absence of IL-4. ET-1 induced a very rapid (< or = 1 min) and dose-dependent release of histamine and serotonin from BMMC cultured in the presence of both IL-3 and IL-4. The effect of ET-1 was quantitatively comparable with IgE/Ag-induced mediator release and comprised up to 20% and 16% of total cellular histamine and serotonin, respectively. In BMMC grown with KL or KL plus IL-3, a substantial effect of ET-1 on amine release was only observed when IL-4 had been included in the culture medium. These IL-4 effects could not be observed if BMMC grown in IL-3 and/or KL were preincubated for 1 or 24 h with IL-4 before activation with ET-1, suggesting that a differentiation process rather than a functional priming effect had been initiated by IL-4. In BMMC, the histamine and serotonin release induced by ET-1 (10(-6) M) was inhibited by an ETA-R-specific antagonist (cyclic [D-Asp-Pro-D-Val-Leu-D-Trp]) in a dose-dependent manner, with complete inhibition at an antagonist concentration of 10(-8) M. ET-1 stimulated leukotriene C4 biosynthesis up to 4.5-fold in BMMC cultured in the presence of IL-4. No such ET-1 effect was observed in BMMC cultured in media containing IL-3, KL, or a combination of both cytokines. Peritoneal cells (containing 2 to 3% serosal mast cells) obtained from BALB/c mice released 87 +/- 2% of histamine within 1 min after challenge with ET-1. Our results demonstrate that ET-1 can directly act as a histamine and serotonin secretagogue and as a stimulator of leukotriene C4 production in mast cells. IL-4 appears to be critically involved in the differentiation of immature mast cell precursors to an ET-1-reactive phenotype. (ABSTRACT TRUNCATED AT 400 WORDS)
The Television Viewing, Dating, and Academics of Young Adults

Purpose of the Study More than ever before, young adults have access to television content. Television programs are no longer relegated to the television set, but can be accessed on desktops, laptops, tablets, and even smartphones. The accessibility of television has increasingly allowed young adults to spend a significant portion of their day viewing these programs. Gathering information on how this viewing is related to their dating and academic habits is important to better understand the decision-making and outcomes for young adults in these two central areas of their lives. The purpose of this study was to measure the relationship between television viewing, dating behavior, dating expectations, dating well-being, academic achievement, and academic behavior of young adults. Method The current research was designed as a quantitative non-experimental descriptive study utilizing survey methodology. The instrument, called the Milmine Social Interaction, Academic, and Media Instrument (MSIAAMI), was used to gather information on participants television viewing habits, dating behaviors, dating expectations, dating relationship well-being, academic achievement, and academic behaviors. The data was gathered from 202 graduate and undergraduate students attending Andrews University in the Spring 2015 semester. Canonical correlational analyses were used to determine the existence of relationships between television viewing, dating, and academics. ANOVAs, zero-order correlations, and t-tests were used to provide additional descriptive information on the sample. Results There was no significant relationship found between television viewing and dating, as well as between dating and academics. A significant relationship was found between television viewing and academics. In particular, it was found that total viewing and entertainment viewing were positively related to skipping class and procrastinating. Participants watched television for an average of about 79 minutes, spent 201 minutes doing homework, 192 minutes studying, and 154 minutes with their dating partner each day. Physical attractiveness was more important for men while women reported that receiving kind acts and compliments was more important. Conclusions Although most of the results turned out to be non-significant, there were still many interesting findings. Further research is needed in order to clarify and provide support for these results. This study helped grow the understanding of how one of the most influential media impacts the young adult’s dating and academics as well as how dating influences academics.
Crowdsourcing in Telework as a New Scalable Business Model

Business processes in our modern world flow with greater speed. This actual trend influences on the business from both sides: positive and negative. Some approaches, such as web 3.0, crowdsourcing have intention to create a comfortable ecosystem for business. In this article, we consider how appropriate data management helps building successful business.
Communication Optimizations for Irregular Scientific Computations on Distributed Memory Architectures

Abstract This paper describes a number of optimizations that can be used to support the efficient execution of irregular problems on distributed memory parallel machines. These primitives (1) coordinate interprocessor data movement, (2) manage the storage of, and access to, copies of off-processor data, (3) minimize interprocessor communication requirements, and (4) support a shared name space. We present a detailed performance and scalability analysis of the communication primitives. This performance and scalability analysis is carried out using a workload generator, kernels from real applications, and a large unstructured adaptive application (the molecular dynamics code CHARMM).
A Kalman Filter Based Link Quality Estimation Scheme for Wireless Sensor Networks

Communication among wireless sensor nodes that employ cheap low-power transceivers is often very sensitive to the variations of the wireless channel. Sensor network routing protocols thus strive to continually adapt to temporal variations in wireless links in order to avoid wasteful transmissions over low-quality links. Such adaptive routing protocols must rely on a scheme that can not only accurately estimate the quality of wireless links in terms of a quantitative measure, such as the packet success rate (PSR), but also quickly adapt to temporal dynamics of the links. Traditionally, the PSR is estimated from the fraction of successful transmissions over a window of test- packets. However, we demonstrate that counting based methods do not react to changes in the wireless channel fast enough and that the only way to address this problem is to estimate the PSR based on the receiver's characteristics and on the signal to noise ratio (SNR) at the receiver. We thus propose a scheme that uses a pre-calibrated SNR-PSR relationship and instantaneous SNR estimates to calculate the PSR of the link. In our scheme, each receiver continuously tracks the SNR using a Kalman Filter to minimize the estimation error and uses a locally available SNR- PSR curve to estimate the PSR. Through extensive experiments we demonstrate that our scheme adapts to variations in the channel faster than counting-based PSR estimators and that it also provides better PSR estimates than these counting-based approaches.
In Vitro Studies of Antiphospholipid Antibodies and Its Cofactor, β2-Glycoprotein I, Show Negligible Effects on Endothelial Cell Mediated Protein C Activation

Summary The effect of sera and purified IgG isolated from plasma of 46 patients with systemic lupus erythematosus (SLE) and 9 healthy donors on the endothelial cell (EC) mediated protein C activation was investigated. Out of the 46 SLE sera used, 19 were antiphospholipid antibodies (aPL) positive. From 12 patients IgG was isolated, of which 6 contained aPL. EC were first incubated with IgG (7 mg/ml) or serum (1: 1 diluted) for 1 h and then tested for their ability to promote protein C activation by thrombin, with the cells either in a monolayer or in a suspension. The normal range (mean of control values ± 2 SD) of protein C activation was 80-120%. In contrast to others, we could not detect an inhibition of protein C activation by any of the patient IgG's or sera. The recently described cofactor for binding of antiphospholipid antibodies to phospholipids, β2-glycoprotein I, was purified and added to the purified IgG's. A combination of these two components did not inhibit the EC mediated protein C activation by thrombin. This study suggests that the inhibition of the protein C activation, mediated by EC, is not a general mechanism by which aPL related thrombosis can be explained.
Semistable bundles on curves and irreducible representations of the fundamental group

This note is an attempt to generalize Bolibruch's theorem from the projective line to curves of higher genus. We show that an irreducible representation of the fundamental group of an open in a curve of higher genus has always a representation as a regular system of differential equations on a semistable bundle of degree 0. Vice-versa, we show that given such a bundle and 3 points on the curve, one can construct an irreducible representation of the curve minus the 3 points such that an associated regular system of differential equations lives on this bundle.
Investigation of bio-oil produced by hydrothermal liquefaction of food waste using ultrahigh resolution Fourier transform ion cyclotron resonance mass spectrometry

Recent research has revealed that more than 1.3 billion tons of food is wasted globally every year. The disposal of such huge biomass has become a challenge. In the present paper, we report the production of the bio-oil by hydrothermal liquefaction of three classes of food waste: meat, cheese and fruits. The highest yield of the bio-oil was observed for meat (∼60%) and cheese (∼75%), while for fruits, it was considerably low (∼10%). The molecular composition of the obtained bio-oil was investigated using ultrahigh resolution Fourier Transform Ion Cyclotron Resonance mass spectrometry and was found to be similar to that obtained from algae. Several thousand heteroatom compounds (N, N2, ON2, etc. classes) were reliably identified from each sample. It was found that bio-oils produced from meat and cheese have many compounds (∼90%) with common molecular formulas, while bio-oil produced from fruits differs considerably (∼30% of compounds are unique).
Unbiased Robust Template Estimation for Longitudinal Analysis in FreeSurfer

Compared with cross-sectional studies, a longitudinal design can significantly reduce the confounding effect of inter-individual morphological variability by using each subject as his or her own control. As a result, longitudinal imaging studies are increasing in popularity in various aspects of neuroscience. Changes in gray matter that makes up the cortical sheet are for example manifested in aging, Alzheimer's disease, Huntington's disease, multiple sclerosis and schizophrenia. In vivo cortical thickness measures could be useful as marker of disease progression or onset; this is an active and important area of research. Longitudinal imaging-based biomarkers are thus of great potential utility in evaluating the efficiency of disease-modifying therapies. For these reasons, developing more robust and reliable measures of cortical, subcortical and white matter atrophy may have a profound clinical impact. The current methods that utilize cross-sectional approaches, in which images are processed individually introduce the natural variability of the brain as a confound. We sought to develop and validate a longitudinal approach that takes advantage of intra-subject longitudinal acquired
Defining the at risk patients for contrast induced nephropathy after coronary angiography; 24-h urine creatinine versus Cockcroft-Gault equation or serum creatinine level

Background: Definitions of chronic kidney disease (CKD) in many catheterization laboratories have relied on the serum creatinine (Scr) rather than glomerular filtration rate (GFR). Regarding that CKD is the primary predisposing factor for contrast induced nephropathy (CIN), we compared the sensitivity of calculated GFR by 24-h Urine creatinine with Cockcroft-Gault (CG) equation and Scr level to define at risk patients for CIN who were undergone coronary angiography (CAG). Materials and Methods: Two hundred fifty four subjects who were candidate for CAG and had normal creatinine level were enrolled. Before CAG, GFR was calculated from a 24-h urine collection, CG equation and a single Scr sample regarding to previously described protocol. Contrast volume used for each case <100 ml. CIN was defined as a 0.5 mg/dL or 25% elevation in the Scr. Results: CIN occurred in 10.6%. Baseline GFR, the volume of contrast agent, and diabetes were the independent risk factors for CIN. GFR was less than 60 ml/min/1.73 m2 in 28% and 23.2% of patients regarding to 24-h urine creatinine and CG equation, respectively. In CIN prediction, 24-h urine creatinine estimated GFR had 85.2%, 59.3% and CG equation GFR had 78.9%, 81.1% sensitivity and specificity, respectively. Conclusion: Although, GFR estimated by CG equation has less sensitivity than GFR calculated from 24-h creatinine in CIN probability, but it is better than Scr alone and because of cost-effectiveness and convenience using of this method, we suggest at least using CG equation for GFR calculation before CIN, especially in diabetic and/or older than 60 years cases.
Effects of Drought and Rehydration on the Physiological Responses of Artemisia halodendron

Artemisia halodendron is a widely distributed native plant in China’s Horqin sandy land, but few studies have examined its physiological responses to drought and rehydration. To provide more information, we investigated the effects of drought and rehydration on the chlorophyll fluorescence parameters and physiological responses of A. halodendron to reveal the mechanisms responsible for A. halodendron’s tolerance of drought stress and the resulting ability to tolerate drought. We found that A. halodendron had strong drought resistance. Its chlorophyll content first increased and then decreased with prolonged drought. Variable chlorophyll fluorescence (Fv) and quantum efficiency of photosystem II (Fv/Fm) decreased, and the membrane permeability and malondialdehyde increased. When plants were subjected to drought stress, superoxide dismutase (SOD) activity degraded under severe drought, but the activities of peroxidase (POD) and catalase (CAT) and the contents of soluble proteins, soluble sugars, and free proline increased. Severe drought caused wilting of A. halodendron leaves and the leaves failed to recover even after rehydration. After rehydration, the chlorophyll content, membrane permeability, SOD and CAT activities, and the contents of the three osmoregulatory substances under moderate drought began to recover. However, Fv, Fv/Fm, malondialdehyde, and POD activity did not recover under severe drought. These results illustrated that drought tolerance of A. halodendron resulted from increased enzyme (POD and CAT) activities and accumulation of osmoregulatory substances.
Development and Validation of the Medication Regimen Complexity Index

BACKGROUND: Medication regimen attributes, such as the number of drugs, dosage frequency, administration instructions, and the prescribed dosage forms, have been shown to influence patient outcomes. No single tool for quantifying the complexity of general medication regimens has been published in the medical literature. OBJECTIVE: To develop and validate a tool to quantify the complexity of prescribed medication regimens. METHODS: Literature findings and the expertise of the authors were used for developing the tool. Eight pharmacy researchers helped in establishing the tool's face and content validity. The new tool was tested on 134 medication regimens from patients with moderate to severe chronic obstructive pulmonary disease. Six regimens with a spread of scores on the tool were presented to a 5–member expert panel that subjectively ranked these regimens to confirm the tool's criterion-related validity. The relationships between scores on the tool and various independent variables were tested to judge the tool's construct validity. Two raters scored 25 regimens using the tool to test its inter-rater and test—retest reliabilities. RESULTS: A 65–item Medication Regimen Complexity Index (MRCI) was developed. The expert panel had strong agreement (Kendall's W = 0.8; p = 0.001) on their individual rankings of the 6 regimens. The panel's consensus ranking had perfect correlation with the MRCI ranking. The total MRCI score had significant correlation with the number of drugs in the regimen (Spearman's Rho = 0.9; p < 0.0001), but not with the age and gender of the patients. Inter-rater and test—retest reliabilities for the total score and scores for individual sections on the MRCI were ≥0.9. CONCLUSIONS: The MRCI is a reliable and valid tool for quantifying drug regimen complexity with potential applications in both practice and research.
National tourism policy for climate change

Tourism will be highly impacted upon by climate change and adaptation and mitigation policies implemented by other agencies. This paper seeks to increase our understanding of the role tourism plays in relation to climate change policies and identifies gaps where specific tourism policy might be required to address climate change. Based on the case studies of Fiji and New Zealand, common areas of concern relating to climate change will be identified, existing policy settings discussed and challenges of the policy development process explored. Existing climate policies were found to cover tourism for many issues, either directly or indirectly, and tourism‐specific policy needs relate mainly to a better integration with these policies, education and capacity building, business performance and marketing. The participatory process and the creation of a tourism‐climate change policy network have proven successful in both case studies.
Ionospheric Threat Parameterization for Local Area Global-Positioning-System-Based Aircraft Landing Systems

Observations of extreme spatial rates of change of ionospheric electron content and the characterization strategy for mitigation applied by the U.S. local area augmentation system are shown. During extreme ionospheric activity, the gradient suffered by a global navigation satellite system user a few kilometers away from a ground reference station may reach as high as 425 mm of delay (at the GPS L1frequency) per km of user separation. The method of data analysis that produced these results is described, and a threat space that parameterizes these possible threats to user integrity is defined. Certain configurations of user, reference station, global navigation satellite system satellite, and ionospheric storm-enhanced density may inhibit detection of the anomalous ionosphere by the reference station.
Sensory quality of soymilk and tofu from soybeans lacking lipoxygenases

Abstract The oxidation of unsaturated lipids by lipoxygenases in soybeans causes undesirable flavors in soy foods. Using a traditional and a nontraditional soy food user group, we examined the cultural difference in perceiving the sensory characteristics of soymilk and tofu produced from soybeans with or without lipoxygenases (Lx123). The two groups described the samples using similar terms. The traditional users preferred the control soy milk and lipoxygenase‐free tofu while the nontraditional users preferred the lipoxygenase‐free soymilk with no preference for tofu. In a separate study, a trained descriptive taste panel compared the odor of soymilk and tofu from control soybeans or those lacking lipoxygenase‐1 and lipoxygenase‐2 (Lx12) or all three isomers (Lx123). The rancid/grassy odor was rated the lowest in Lx123 products, followed by Lx12 products with the control products given the highest rating. The Lx12 and Lx123 products were also sweeter and less bitter than the controls. Taken together, our results demonstrated that soybeans lacking lipoxygenases can produce soy foods with less undesirable aromas and are therefore likely more acceptable to the consumers.
Arbeitsrelevante Einstellungen bei Call Center-Agenten:

Zusammenfassung. Call Center stellen einen zunehmend wachsenden Zweig der Dienstleistungsbranche dar. Man kann zwischen verschiedenen Call Center-Typen unterscheiden, namlich zwischen Inhouse- und Outhouse-Call Centern. Ferner kann zwischen Inbound- und Outbound-Telefonmarketing unterschieden werden. Die objektive Arbeitssituation stellt sich fur Outbound-Agenten im Vergleich zu Inbound-Agenten und fur Inhouse-Call Center im Vergleich zu Outhouse-Call Centern positiver dar, daher wurden auch positivere Arbeitseinstellungen in diesen Bereichen erwartet. Vergleiche wurden bezuglich verschiedener Foci von Identifikation, dem Teamklima, selbstberichteten Extra-Rollen-Verhaltensweisen (OCB), Zufriedenheit, intrinsischer Motivation sowie verschiedenen Subskalen des Job Diagnostic Survey (JDS) angestellt. Insgesamt bearbeiteten 211 Call Center-Agenten einen standardisierten Fragebogen. Die Hypothesen wurden teilweise bestatigt: Im Vergleich zu Mitarbeitern des Outhouse-Call Centers zeigten Inhouse-Call Center-Ag.