Miracle-dz/UniFAR-FTUs huggingface dataset:
Serum total acid phosphatase for monitoring the clinical course of giant cell tumors of bone—26 patients with 5 local recurrences

Background Giant cell tumor of bone (GCT) is a bone-destroying tumor that sometimes recurs locally after treatment. A recent study showed increased levels of serum total acid phosphatase (TACP). Methods We assessed TACP in the serum of 26 patients with primary GCT, and in 5 of them who developed a local recurrence. Results We found a correlation between TACP level in serum and tumor size. TACP levels that were elevated preoperatively in patients with GCT became normalized after surgery, but increased in 3 of the 5 patients with local recurrence. Interpretation TACP could be used as a tumor marker for monitoring response to treatment of GCT.
Gelatin-based delivery systems for cancer gene therapy

Gelatin is a natural, biocompatible, nontoxic, edible, and inexpensive macromolecule. These properties result in its wide application in pharmaceutical, medical, and cosmetic products. Recently, it has been used for the delivery of such gene therapeutic entities as plasmid DNA. This review discusses the in vivo and in vitro studies using gelatin for delivery of therapeutic genes to cancerous cells. Recent studies show that present cancer gene therapy using gelatin is lacking in both efficiency and specificity in comparison with viral vectors, whereas complexes of therapeutic DNA with modified gelatin possibly offer a safe and efficient strategy for systemic administration of therapeutic genes to solid tumors compared to injection of naked plasmid DNA. The future of these promising approaches lies in the development of better techniques for preparing gelatin–gene complexes with the aim of a gelatin-based cancer gene therapy with comparable efficiency to viral vectors but with the added advantage of biosafety for patients.
Embedded mobile farm robot for identification of diseased plants

This paper presents the development of a mobile robot used in farms for identification of diseased plants. It puts forth two of the major aspects of robotics namely automated navigation and image processing. The robot navigates on the basis of the GPS (Global Positioning System) location and data obtained from IR (Infrared) sensors to avoid any obstacles in its path. It uses an image processing algorithm to differentiate between diseased and non-diseased plants. A robotic platform consisting of an ARM9 processor, motor drivers, robot mechanical assembly, camera and infrared sensors has been used. Mini2440 microcontroller has been used wherein Embedded linux OS (Operating System) is implemented.
Persistent primitive trigeminal artery demonstrated by vertebral arteriography.

A case of persistent primitive trigeminal artery is described, in which a stenosis of the internal carotid artery was present on the same side. The persistent abnormal fetal communication was filled on vertebral arteriography only. However, on the basis of the dilution effect seen on the carotid arteriogram, it could be conjectured that an abnormal communication existed between the carotid syphon and the vertebral artery and that the blood flow was directed from the vertebral artery to the carotid artery.
HEAT SHOCK PROTEIN 70 B ’ ( HSP 70 B ’ ) EXPRESSION AND RELEASE IN RESPONSE TO HUMAN OXIDIZED LDL IMMUNE COMPLEXES IN MACROPHAGES

HUMAN OXIDIZED LDL IMMUNE COMPLEXES IN MACROPHAGES Kent J. Smith, Waleed O Twal, Farzan Soodavar, Gabriel Virella, Maria F Lopes-Virella, and Samar M Hammad From Department of Regenerative Medicine and Cell Biology, Microbiology and Immunology, and the Division of Endocrinology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, and the Department of Veteran Affairs, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC 29401 Running head: HSP70B’ induction by oxidized LDL immune complexes Address correspondence to: Samar M. Hammad, Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, 114 Doughty Street, 630B, P.O. Box 250776, Charleston, SC, 29425. Tel. : (843) 876-5200; Fax: (843) 792-0664; E-Mail: hammadsm@musc.edu
Graduates of foreign medical schools: progression to certification by the Educational Commission for Foreign Medical Graduates

The application process leading to certification by the Education Commission for Foreign Medical Graduates (ECFMG) was studied using the group of 9,491 graduates of foreign medical schools who initiated their applications in 1988. Using the ECFMG's database, these applicants' countries of citizenship, examination histories, certification status, and exchange visitor status were determined for a period of seven years and 9 months, ending in September 1995. Within that time, 45% of these applicants became ECFMG-certified, and 26% of that group entered residency programs accredited by the Accreditation Council for Graduate Medical Education. Of the total number of non-U.S. citizens (2,243) who entered such programs, 61% did so as exchange visitor physicians. The remainder had other kinds of visa status, such as permanent resident, or had become U.S. citizens. Although U.S. citizens and non-U.S. citizens achieved certification at the same rate (45%), the U.S. citizens had greater success in obtaining positions in graduate medical education (GME). Seventy-four percent of the ECFMG-certified certified U.S. citizens entered GME, versus 57% of the ECFMG-certified non-U.S. citizens. The status of the 55% of the 9,491 applicants who did not obtain certification is discussed; a portion of this group of this group continues to pursue certification. Details and requirements of the ECFMG certification process are also described.
Factor structure of health and oral health-related behaviors among adolescents in Arusha, northern Tanzania

Abstract Objective. This study aimed to evaluate the factor structure of health and oral health-related behaviors and it's invariance across gender and to identify factors associated with behavioral patterns. Materials and methods . A cross-sectional study included 2412 students attending 20 secondary schools in Arusha. Self-administered questionnaires were completed at school. Results . Principal component analysis of seven single health and oral health-related behaviors (tooth brushing, hand wash after latrine, hand wash before eating, using soap, intake of sugared mineral water, intake of fast foods and intake of sweets) suggested two factors labeled hygiene behavior and snacking. Confirmatory factor analyses, CFA, provided acceptable fit for the hypothesized two-factor model; CFI = 0.97. Multiple group CFA across gender showed no statistically significant difference in fit between unconstrained and constrained models (p = 0.203). Logistic regression revealed ORs for hygiene behaviors of 1.5, 0.5, 1.5, 1.5 and 0.6 if being a girl, current smoker, reporting good relationship with school, access to hygiene facilities and bad life satisfaction, respectively. ORs for snacking were 1.3, 1.4, 0.4 and 0.5 if female, in the least poor household quartile, low family socio-economic status and high perceived control, respectively. Conclusion . The two factors suggest that behaviors within each might be approached jointly in health promoting programs. A positive relationship with school and access to hygiene facilities might play a role in health promotion. Provision of healthy snacks and improved perceived behavioral control regarding sugar avoidance might restrict snacking during school hours.
Experimental Results on Item-Based Algorithms for Independent Domain Collaborative Filtering

A research analysis on item-based algorithms for collaborative filtering is presented. The aim of the presented activity was to find a configuration of an item-based algorithm capable of providing good results but also independent from the data set. Four data sets were used for the algorithm validation: Netflix, MovieLens, BookCrossing, and Jester. The experimentation involved the following aspects: similarity computation, size of the neighbourhood, prediction computation, minimum number of co-rated items. Results were evaluated in terms of root mean squared error (RMSE). The result of the activity is an independent domain configuration for an item-based algorithm which produced satisfactory results with most of the above mentioned data sets.
Domain‐specific impairment of source memory following a right posterior medial temporal lobe lesion

This single case analysis of memory performance in a patient with an ischemic lesion affecting posterior but not anterior right medial temporal lobe (MTL) indicates that source memory can be disrupted in a domain‐specific manner. The patient showed normal recognition memory for gray‐scale photos of objects (visual condition) and spoken words (auditory condition). While memory for visual source (texture/color of the background against which pictures appeared) was within the normal range, auditory source memory (male/female speaker voice) was at chance level, a performance pattern significantly different from the control group. This dissociation is consistent with recent fMRI evidence of anterior/posterior MTL dissociations depending upon the nature of source information (visual texture/color vs. auditory speaker voice). The findings are in good agreement with the view of dissociable memory processing by the perirhinal cortex (anterior MTL) and parahippocampal cortex (posterior MTL), depending upon the neocortical input that these regions receive. © 2007 Wiley‐Liss, Inc.
Visual Analysis and Exploration of Entity Relations in Document Collections

Interactive text visualization can help users explore and gain insights into complex and often large document sets. One popular visualization strategy to represent such collections is to depict each document as a glyph in 2D space. These spaces have proven effective, especially when combined with interactive exploration methods. However, current exploratory approaches are largely limited to single areas of a 2D spatialization, lacking support for important comparative exploration and analysis tasks. In this paper, we extend a flexible focus+context exploration technique to tackle this challenge. In particular, based on practical tasks from the digital humanities, we focus on exploring and investigating relationships between entities in large document collections. Our approach uses natural language processing to extract characters and places, including information about their relationships. We then use linked views to facilitate visual analysis of extracted information artifacts. Based on two usage scenarios, we demonstrate successful applications of the approach and discuss its benefits and limitations.
Temperature prediction for multi-core microprocessors with application to Dynamic Thermal Management

Temperature is among the most important factors limiting CPU performance. To ensure stable and reliable operation temperature has to be limited. In this paper we present a method for predicting temperature of a multi-core microprocessor based on it's high-level thermal model. Temperature prediction is then utilised in a Dynamic Thermal Management algorithm that can exploit performance optimisation opportunities while ensuring operation below temperature limit. The DTM algorithm uses frequency and voltage scaling of the CPU cores and task migration and was evaluated on a physical computer with a quad-core CPU.
THE AMBIGUITY TOLERANCE OF TURKISH LANGUAGE PREPARATION CLASS AND IMPACT OF METACOGNITIVE AWARENESS LEVEL ON READING COMPEHENSION SUCCESS

Belirsizlik hosgorusu kisilerarasi iletisimde bireyin psikolojik alt yapisina gondermede bulunan bir kavramdir (Budner,1962). Bu kavram ayrica yabanci dil ogretiminde, sinif ici uygulamalarda ogrenen odakli bir faktor olarak degerlendirilmektedir (Ely, 1995). Bireyin sinif ici grup calismalarinda iletisim icinde oldugu diger bireye karsi gosterdigi hosgoru, onun belirsizlik hosgoru duzeyiyle ilintilidir ve bu ozellik yabanci dil basarisini etkileyebilmektedir. Okuma, bireyin gelisimsel surecine isaret eden ve yasam kalitesini arttiran bir etkinliktir. Okuma etkinligi icinde olan bir birey ayni zamanda duyus, etkilesim, algilama, deneyim, dusunme, ogrenme, cagrisim, etkileme ve yapilandirma gibi karmasik ve cok yonlu zihinsel bir surecin de aktoru konumundadir. Okuma eyleminde varilmak istenen hedef okudugunu anlamadir. Diger yandan okudugunu anlama, bireyin bilincli ve bilissel bir caba gostermesini gerektirmektedir. Bu bakimdan birey onceki bilgileriyle okuduklari arasinda okuma amaclarina yonelik bir ilgi kurma yoluna gitmelidir (Kent,2002). Okudugunu anlama, bireyin yaraticiliginda ve uretkenliginde rol oynayan en temel bilissel etkinliklerdendir. Bu bilissel caba sonucunda zihinsel gelisimini yeniden yapilandirma imkâni bulan birey (Block,2004), ayni zamanda ogrenmeyi ogrenmis, bilgiyi uretime donusturecek konuma gelmis sayilmaktadir. Okumayla ilgili calismalarda da ust bilissel arastirmalarda Flavell ve Wellman’in ust bilis taksonomisinden yararlanilmaktadir. Ana kutlenin okuma stratejilerinin belirlenmesinde de soz konusu taksonomiyi temel alan Barr, Kamil, Monsenthal’in (1984) kuramsal acilimlarindan yararlanilmistir. Calismada, cok kulturlu bir ortamda egitim goren Kirgizistan-Turkiye Manas Universitesi, Turkce Hazirlik Sinifi ogrencilerinin belirsizlik hosgoru duzeylerinin ve ust bilissel farkindaliklarinin okudugunu anlama basarisina etkisi arastirilmistir. Bu amacla 550 hazirlik sinifi ogrencisine demografik sorulari da iceren ve Ely (1995) tarafindan gelistirilen Ikinci Yabanci Dil Belirsizlik Hosgorusu Olcegi (SLTAS) ve Mokhtari ve Reichard tarafindan gelistirilen (2002) Okuma Stratejileri Ust Bilissel Farkindalik Envanteri (MARSI) uygulanmis, elde edilen veriler cok degiskenli istatistiksel teknikler yardimiyla cozumlenmistir
Physical activity levels among children aged 9-13 years--United States, 2002.

Three national health objectives for 2010 (objectives no. 22-6, 22-7, and 22-11) aim to increase levels of physical activity and reduce sedentary behavior among children and adolescents. To promote a healthy, more active lifestyle among U.S. youth, CDC developed the Youth Media Campaign (YMC), a national initiative to encourage children aged 9-13 years to engage in and maintain high levels of regular physical activity. To provide a baseline assessment of physical activity levels among children aged 9-13 years, CDC conducted the YMC Longitudinal Survey (YMCLS), a nationally representative survey of children aged 9-13 years and their parents. This report presents data from the survey, which indicate that 61.5% of children aged 9-13 years do not participate in any organized physical activity during their nonschool hours and that 22.6% do not engage in any free-time physical activity. Improving levels of physical activity among this population will require innovative solutions that motivate children and that address parents' perceived barriers to their children engaging in physical activity.
Minimum Mean Square Error estimation of speech spectral amplitude using super-Gaussian priors

This paper deals with the spectral estimation methods for speech enhancement. We firstly show the proper matching of the super-Gaussian distribution with the histogram of the speech spectral amplitude. For the selected speech material, the best matching is achieved when the super-Gaussian parameters are set to ν = 0, μ = 2.5. We then derive Minimum Mean Square Error (MMSE) estimator for speech DFT amplitude when clean speech spectral amplitudes are modeled by super-Gaussian probability distribution and noise DFT coefficients are presented as Gaussian random variables. Evaluation results, in terms of different objective quality measures, show that the MMSE estimator based on super-Gaussian distribution (with parameters ν = 0, μ = 2.5) leads to superior results in speech enhancement.
Temporal effects of ethanol consumption on energy homeostasis, hepatic steatosis, and insulin sensitivity in mice.

BACKGROUND Alcoholic liver disease (ALD) progresses from steatosis to inflammation, fibrosis, and cirrhosis. Although ALD has been associated with insulin resistance, it is unclear whether insulin resistance coincides with the development of steatosis. METHODS We studied the temporal relationship of steatosis and glucose homeostasis in mice fed a Lieber-DeCarli liquid control or ethanol (EtOH) diet for 2, 4, or 8 weeks. We studied the effects of alcohol consumption on energy balance, body composition, and hepatic lipids. Glucose tolerance test was performed, and insulin sensitivity was evaluated with hyperinsulinemic-euglycemic clamp. RESULTS EtOH-fed mice developed hepatic steatosis over time as compared with control-fed mice despite similar energy intake and expenditure, and gain in body weight and fat. EtOH-fed mice developed glucose intolerance as early as 2 weeks, while insulin resistance developed at 4 weeks. A hyperinsulinemic clamp study at 8 weeks revealed both hepatic and peripheral insulin resistance in EtOH-fed mice. Insulin resistance was associated with hepatic steatosis, increased ceramide levels, and Perilipin 2 expression. CONCLUSIONS Chronic EtOH consumption leads to the development of hepatic steatosis, impaired glucose tolerance, and insulin resistance. These changes are independent of energy intake or expenditure, weight, whole body fat content, and inflammation. A better understanding of the processes linking EtOH-induced steatosis and abnormal glucose homeostasis may lead to novel therapies targeting the progression of ALD.
Rapid dengue diagnosis and interpretation.

Outbreaks of dengue fever (DF) and dengue haemorrhagic fever (DHF) pose a serious threat to more than 85 tropical and sub-tropical countries throughout the world. The World Health Organization has identified dengue to be one of the most under-reported diseases, with actual cases in the millions. It is also recognised as one of the most important and rapidly rising mosquito-transmitted infections in the world. The alar-ming increase in cases may be due to many factors, including rapid population growth, expanding urbanization, rising economies, inadequate municipal water supplies, and difficulties in handling refuse disposal. These lead to an abundance of new breeding sites for the mosquito vectors of the disease, while human migration patterns disperse vectors and viruses into new areas. National public health authorities are often unable to deal successfully with dengue outbreaks and epidemics. Although a vaccine developed in Thailand against dengue viruses is on the horizon, it will take a few years before i t becomes available.
Title Iterative algorithms based on decoupling of deblurring anddenoising for image restoration

In this paper, we propose iterative algorithms for solving image restoration problems. The iterative algorithms are based on decoupling of deblurring and denoising steps in the restoration process. In the deblurring step, an efficient deblurring method using fast transforms can be employed. In the denoising step, effective methods such as the wavelet shrinkage denoising method or the total variation denoising method can be used. The main advantage of this proposal is that the resulting algorithms can be very efficient and can produce better restored images in visual quality and signalto-noise ratio than those by the restoration methods using the combination of a data-fitting term and a regularization term. The convergence of the proposed algorithms is shown in the paper. Numerical examples are also given to demonstrate the effectiveness of these algorithms.
Microdosimetric analysis of alpha-particle-emitting targeted radiotherapeutics using histological images.

UNLABELLED The purpose of this study was to evaluate the therapeutic efficacy and limitations of alpha-particle-emitting radiolabeled compounds by means of 2-dimensional histological images and distribution of activity on a microscopic level. METHODS A microdosimetric approach based on histological images is used to analyze the therapeutic effectiveness of alpha-particle-emitting (211)At and (213)Bi conjugated to 201B monoclonal antibody (mAb), which is reactive with murine lung blood vessels for the treatment of EMT-6 lung tumor colonies in nude mice. Autoradiography images were used to define the tissue morphology and activity distribution within lung tissues. Two animal groups were studied: Group A consisted of animals bearing small tumors (<130 micro m) and group B consisted of larger tumors (<600 micro m). Probability density functions (pdf) described the variability in average absorbed dose and survival probability among normal and tumor target cells and, in turn, were used to assess the survival fraction of tumor and normal tissue. RESULTS The average absorbed dose to tumor cells per unit cumulated activity concentration for animals in group A was 1.10 x 10(-3) and 1.37 x 10(-3) Gy g MBq(-1) s(-1) for (211)At and (213)Bi, respectively, and for animals in group B was 3.8 x 10(-4) and 5.6 x 10(-4) Gy g MBq(-1) s(-1) for (211)At and (213)Bi, respectively. The fraction of tumor cells that received a zero absorbed dose for animals in group A was 0.04% for (213)Bi and 0.2% for (211)At and for animals in group B was 25% for (213)Bi and 31% for (211)At. Both (213)Bi- and (211)At-labeled 201B mAb were effective therapies for animals with small tumors, where predicted therapeutic effectiveness was consistent with experimental findings; however, they were ineffective for animals with larger tumors. CONCLUSION Microdosimetric methods based on knowledge of tissue morphology and activity distribution on a small-scale level can be a useful tool for evaluating a priori the therapeutic efficacy and limitations of targeted alpha-particle endoradiotherapeutic strategies.
L Spirometric Data Classification on the Basis of Statistical Data Mining

Respiratory disease is a medical term that encompasses pathological conditions affecting the organs and tissues. A lungs disease affects health condition of many people. Lungs diseases can be curable in early detection. Spirometry is valuable for diagnosing specific lung disorders as well as detecting lung disease at an early stage. Spirometry (the measuring of breath) is the most common of the pulmonary function tests and uses an instrument called a spirometer to measure the amount of air entering and leaving the lungs. This test is often used to help doctors diagnose and determine the severity of various respiratory diseases. The output of spirometry is in the form of graphs i.e. flow-volume loop and volume-time curve. This graph gives various parameters that are used for spirometry modelling. In this paper, various pulmonary diseases such as obstructive, restrictive and mixed lung disorders are classified using statistical data mining approach. This classification helps a physician in diagnosis process of various diseases. This approach is used to increase the efficiency of classification.
Comparative accuracy of fitness tracking modalities in quantifying energy expenditure

Abstract The purpose of this study is to compare the accuracy of wrist-worn, consumer-grade pedometers and earbud sensor technology in quantifying energy expenditure. Nineteen participants (24.6 ± 3.1 years) performed 5 min exercise stages on a treadmill (80.5 m/min, 107.3 m/min, 134.1 m/min and 160.9 m/min) while measuring energy expenditure via the Fitbit Charge pedometer and Jabra Sport Pulse Wireless Earbuds, comparing with indirect calorimetry. Paired samples t-tests were used to calculate differences and Pearson correlations to examine associations between kcals measured from the Fitbit and Jabra earbuds from indirect calorimetry. Results indicate significant underestimations of kcals for both devices at all speeds except one (Jabra earbuds at 107.3 m/min). Moderate correlations were observed for the Fitbit at 107.3 m/min and 107.3 m/min, and 134.1 m/min for the Jabra earbuds. Both devices considerably underestimated kcals, suggesting that caution be used when incorporating such data into fitness/health goals.