Miracle-dz/UniFAR-FTUs huggingface dataset:
The complete mitochondrial genome of the spotted longbarbel catfish, Hemibagrus guttatus (Siluriformes, Bagridae)

Abstract Spotted longbarbel catfish, Hemibagrus guttatus (Siluriformes, Bagridae), is regarded as one of the “four famous fish” in the Pearl River system in China. So far, very few genomic resources from this species were available. In the present study, the complete mitochondrial genome of H. guttatus was determined to be 16,528 bp long circular molecule with a typical gene arrangement of vertebrate mitochondrial DNA. It includes 22 transfer RNA genes, 2 ribosomal RNA genes, 13 protein-coding genes, and a non-coding control region (D-loop). The complete mtDNA genome sequence obtained in this study would be useful for studying genetic diversity and phylogenetics in H. guttatus and related taxa in future.
A warrant for applied palaeozoology

It has been argued by some neozoologists (those who study living animals) that the palaeozoological record is biased and incomplete (relative to an existing biological community) and therefore should not be consulted for purposes of conservation biology. An article published in a biology journal in 2011 lists numerous reasons why natural history collections (NHCs) of skins and skulls of animals collected over the past century or two are exceptionally valuable to conservation biologists because those collections provide significant time depth to numerous variables that document global biological change. Many of those same variables can be, and have been, identified in the palaeozoological record. Those variables are of major value to conservation biology, whether their values are taken from 100‐year‐old NHCs or from palaeozoological remains. Empirical examples in which the identified variables are measured in palaeozoological contexts indicate that the palaeozoological record should indeed be consulted by conservation biologists and can no longer be considered unsatisfactory for modern resource management.
A perspective on the use of psychoeducation, cognitive-behavioral therapy and interpersonal therapy for bipolar patients.

OBJECTIVES Although pharmacological treatment is at present essential for treating bipolar patients, a number of psychological interventions have recently been shown to be efficacious as add-on therapies for the prophylactic treatment of bipolar illness. The study aimed critically to examine the efficacy of several tested patient-focused therapies. METHODS A systematic review of the literature on this topic was performed, using MEDLINE, PSYCLIT and CURRENT CONTENTS. 'Bipolar', 'Psychotherapy', 'Psychoeducation', 'Interpersonal' and 'Cognitive-behavioral' were entered as keywords. RESULTS To date, psychoeducation and cognitive-behavioral therapy are the psychological interventions that have been shown to be more efficacious in the prophylaxis of new recurrences. There remains a need for studies investigating the role and efficacy of psychological interventions during acute phases of the illness. CONCLUSIONS As their therapeutic goals are complementary, a combination of psychotherapy and pharmacotherapy may allow patients to achieve better symptomatic and functional recovery. Further research is needed to determine which patients may be better candidates for psychological interventions and to estimate the relative effects of the different components of psychological approaches on outcome.
DOA Estimation of Underwater Acoustic Signals Based on PCA-kNN Algorithm

Array signal processing is an important branch of signal processing, and direction of arrival (DOA) estimation is an important research direction in array signal processing, involving smart antenna, underwater acoustic array and other fields. This paper presents a narrow-band DOA estimation algorithm based on PCA (Principal Component Analysis) and kNN (k-Nearest Neighbor). Firstly, PCA algorithm is used to reduce the dimension of the covariance matrix of the signal to reduce the complexity of the model. Then kNN algorithm is used to build the classification model. Through the prior knowledge of the classification about covariance matrix and the corresponding direction, the unknown signal can be estimated quickly and accurately. In this paper, the software simulation is used to prove the validity and reliability of the algorithm by comparing with kNN algorithm and SVM algorithm.
Early Pharmacological Treatment of Delirium May Reduce Physical Restraint Use

Introduction: Evidence surrounding pharmacological treatment of delirium is limited. The negative impact of physical restraints on patient outcomes in the intensive care unit (ICU), however, is well published. The objective of this study was to evaluate whether initiating pharmacologic delirium treatment within 24 hours of a positive screen reduces the number of days in physical restraints and improves patient outcomes compared with delayed or no treatment. Methods: Patients from a mixed ICU with a documented positive delirium score using the Intensive Care Delirium Screening Checklist were retrospectively grouped based on having received pharmacologic treatment within 24 hours of the first positive screen or not. Primary end points were number of days spent in physical restraints and time to extubation after delirium onset. Secondary end points included hospital and ICU length of stay (LOS) and survival to discharge. Results: Two hundred intubated patients were either pharmacologically treated (n = 98) or not treated (n = 102) within 24 hours of the first positive delirium score. Patients receiving treatment spent a shorter median time in restraints compared with patients who were not treated (3 vs 6 days; P < .001), and had a shorter median time to extubation (3 vs 6.5 days; P < .001). The treatment group also experienced a shorter ICU LOS (9.5 vs 16 days; P < .001) and hospital LOS (14.5 vs 22 days; P < .001) compared with the no-treatment group. Conclusions: Delirious patients who received pharmacological treatment within 24 hours of the first positive screen spent fewer days in physical restraints and less time receiving mechanical ventilation compared with those who did not. Although delirium management is multifactorial, early pharmacological therapy may benefit patients diagnosed with delirium.
Impact of HLA-A,B,C Allele Mismatches on Outcome after Unrelated Blood Stem Cell Transplantation in Whites

At our institution the selection of unrelated donors for hematopoietic stem cell transplantation (HSCT) relies on low resolution human leukocyte antigen (HLA)-A,B and high resolution HLA-DRB1,DQB1 DNA-based typing. To answer the question of whether routine high resolution HLA-A,B,C typing might improve HSCT outcome, 171 white “HLA-identical” donor/recipient pairs, as stated by our pretransplant tissue typing routine, were retyped for HLA-A,B,C using sequence based typing (SBT). The numbers of HLA-A,B,C allele mismatches detected by SBT were correlated to established clinical endpoints of HSCT outcome. We found 33.9% of the study transplants to be fully HLA-A,B,C matched, whereas 66.1 % exhibited one through four donor/recipient HLA-A,B,C allele mismatches. However, statistical analysis could not demonstrate an impact of the number of HLA-A,B,C allele mismatches on overall survival and other analyzed endpoints. Thus, our series of white donor/recipient pairs does not suggest the routine use of HLA-A,B,C SBT to improve HSCT outcome substantially.
Research on Chirp Signal Denoising Algorithm Based on IoT

With the continuous development of IoT, smart grid receives widespread attention. Aiming at the problem of poor performance of the Rake receiver in a wideband micro-power wireless communication system under a low signal-to-noise ratio, the non-stationarity of the Chirp signal used in the system and the adaptability of the non-stationary signal of the denoising method are proposed. A complementary empirical mode decomposition (CEEMD) combined with wavelet threshold denoising algorithm to improve the receiver's signal-to-noise ratio. The CEEMD algorithm can not only handle non-stationary signals well, but also overcome the modal aliasing phenomenon. However, using only the CEEMD algorithm, some effective information will be lost when removing high-noise high-frequency IMF components. Therefore, this paper combines CEEMD decomposition with wavelet threshold denoising, and performs wavelet threshold denoising processing on high-frequency IMF components decomposed by CEEMD to extract useful information from high-frequency components. Through matlab software simulation, the signal-to-noise ratio has been improved by about 1dB.
Antithrombin III alger: A new case of Arg 47 ← cys mutation

Fig. 1. Nucleotide sequence of the region containing the arg 47cys mutation. The construction of a genomic library, screening, and isolation of the AT I11 gene were performed as previously described [6]. The DNA sequence was determined by the dideoxy method of Sanger et a1 [7]. The mutated nucleotides are indicated by arrows at a T on the noncoding strand (on the left) and an A on the coding strand (on the right). A partial sequence of exon 2 of the AT I11 Alger gene and of the normal AT 111 gene are compared below, as well as their deduced amino acid sequences. Numbers correspond to the position of the residues in the AT I11 protein sequence.
Functional CFTR in endosomal compartment of CFTR-expressing fibroblasts and T84 cells.

It was proposed that the cystic fibrosis transmembrane conductance regulator (CFTR) functions in the endosomal compartment as a adenosine 3',5'-cyclic monophosphate (cAMP)-regulated Cl channel that regulates endosomal acidification (J. Barasch, B. Kiss, A. Prince, L. Saiman, D. Gruenert, and A. Al-Awqati, Nature Lond. 352: 70-73, 1991). This hypothesis was tested in stably transfected Swiss 3T3 fibroblasts expressing CFTR or delta F508 CFTR and in T84 epithelial cells that normally express CFTR. In fibroblasts, the time course of pH in individual endosomes was measured by quantitative image analysis after 1 min pulse labeling with 2 microM carboxyfluorescein (Cf)-tetramethylrhodamine-transferrin (K. Zen, J. Biwersi, N. Periasamy, and A. S. Verkman. J. Cell Biol. 119: 99-110, 1992). Average endosomal pH reached 6.20 +/- 0.07 (SE) after 15 min in the mock-transfected cells with a half time of approximately 3 min; pH was slightly lower (5.97 +/- 0.06) in the CFTR-expressing fibroblasts. The difference did not result from a subpopulation of highly acidic endosomes. Forskolin (10 microM) increased average pH to 6.62 +/- 0.03 and abolished the difference. For determination of Cl conductance, endosomes in fibroblasts and T84 cells were labeled with Cf-dextran (5 mg/ml); dissipation of the endosomal pH gradient was measured in response to rapid addition of the protonophore carbonyl cyanide m-chlorophenylhydrazone (CCCP; 20 microM). Because the proton flux across the endosomal membrane is limited by the movement of K and Cl, the rate of alkalinization (dpH/dt) after CCCP addition provided a measure of endosomal Cl conductance. In CFTR-expressing fibroblasts, forskolin (10 microM) increased dpH/dt 1.6 +/- 0.2-fold (n = 14). (ABSTRACT TRUNCATED AT 250 WORDS)
A 15-MHz Bandwidth 1-0 MASH  $\Sigma \Delta $ ADC With Nonlinear Memory Error Calibration Achieving 85-dBc SFDR

A 1-0 MASH ΣΔ analog-to-digital converter (ADC) demonstrates a digital linearization technique for the first time treating integrator distortion with memory and capacitor mismatch errors. A two-tap sequential polynomial derived from an output-referred error analysis accurately models the non-ideality of a first-order modulator. The model parameters are extracted by correlating various moments of the ADC digital output with a one-bit pseudorandom noise (PN) superimposed on the input, largely reducing the circuit overhead associated with the nonlinear calibration. The prototype ADC employing amplifiers with a gain of roughly 30 dB measures an 85-dBc spurious-free dynamic range (SFDR) and a 67-dB signal-to-noise and distortion ratio (SNDR) for a 1.1- VPP ( -1-dBFS), 4.99-MHz sinusoidal input at 240 MHz sampling clock (8× OSR) with a 7.5-msec calibration time. For a 1.1- VPP two-tone input at 14.9 MHz and 15.1 MHz, the third-order intermodulation product (IM3) after calibration is 87.1 dBc, which is over 30 dB better than that without calibration. The core ADC consumes 37 mW from a 1.25-V supply and occupies 0.28 mm 2 in a 65-nm CMOS low-leakage digital process in which the transistor threshold voltages are around 0.5 V.
A deep learning framework for financial time series using stacked autoencoders and long-short term memory

The application of deep learning approaches to finance has received a great deal of attention from both investors and researchers. This study presents a novel deep learning framework where wavelet transforms (WT), stacked autoencoders (SAEs) and long-short term memory (LSTM) are combined for stock price forecasting. The SAEs for hierarchically extracted deep features is introduced into stock price forecasting for the first time. The deep learning framework comprises three stages. First, the stock price time series is decomposed by WT to eliminate noise. Second, SAEs is applied to generate deep high-level features for predicting the stock price. Third, high-level denoising features are fed into LSTM to forecast the next day’s closing price. Six market indices and their corresponding index futures are chosen to examine the performance of the proposed model. Results show that the proposed model outperforms other similar models in both predictive accuracy and profitability performance.
PRODUKSI, DISTRIBUSI, DAN KONSUMSI DALAM ISLAM

Pola konsumsi dan perilaku produksi menentukan roda perekonomian. Al-Qur’an sebagai sumber ajaran, memiliki ajaran tentang konsumsi, produksi dan distribusi disamping aktivitas-aktivitas perekonomian lainnya. Dalam konteks produksi, tentu saja produsen muslim sama sekali sebaiknya tidak tergoda oleh kebiasaan dan perilaku ekonom-ekonom i yang bersifat menjalankan dosa, memakan harta terlarang, menyebarkan permusuhan, berlawanan dengan sunnatullah, dan menimbulkan kerusakan di muka bumi. Walau bagaimanapun, secanggih alat untuk menghitung nikmat Allah pasti tidak akan menghitungnya. Dalam konseptual konsumsi ada beberapa prinsip yang harus dipatuhi oleh konsumen muslim, yang antara lain : prinsip halal dan baik, prinsip ketiadaan mengikuti hawa nafsu, prinsip sukur. Sistem ekonomi Islam menawarkan sistem penditribusian ekonomi yang mengedepankan nilai kebebasan dalam bertindak dan berbuat dengan dilandasi oleh ajaran agama serta nilai keadilan dalam kepemilikan yang disandarkan pada dua sendi, yaitu kebebasan dan keadilan
Assessment of Nutritional Status of Adolescent Girls by Mid-Upper Arm Circumferences of Paschim Medinipur, India

Copyright: © 2016 De K. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Introduction MUAC is the circumference of the left upper arm, measured at the mid-point between the tip of the shoulder and the tip of the elbow (olecranon process and the acromium). In children, MUAC is useful for the assessment of nutritional status. It is good at predicting mortality by iMUAC alone or MUAC for age; it also predicted death in children better than any other anthropometric indicator. Measurements of adult MUAC have long been known to reflect changes in adult body weight [1]. This advantage of MUAC was greatest when the period of follow-up was short. Ferro-Luzzi and James have proposed MUAC cut-off points for use in screening acute adult under nutrition. They are based on extrapolation from more normally nourished populations in developing countries, Under nutrition is outcome of in sufficient food intake and repeated infected disease, among total adolescent population 88% belong to developing country [2,3]. Adolescent of developing countries are at greater risk of undesirable consequences of under nutrition. In this study MUAc act as tool to study malnutrition. Roc curve in this study helps to determine malnutrition by MUAC.
Maps Multilabel Segmentation Update App . Models with New Frame Processing Block Feature Trajectories Motion Estimation App

The exponentially increasing use of moving platforms for video capture introduces the urgent need to develop the general background subtraction algorithms with the capability to deal with the moving background. In this paper, we propose a multilayer-based framework for online background subtraction for videos captured by moving cameras. Unlike the previous treatments of the problem, the proposed method is not restricted to binary segmentation of background and foreground, but formulates it as a multi-label segmentation problem by modeling multiple foreground objects in different layers when they appear simultaneously in the scene. We assign an independent processing layer to each foreground object, as well as the background, where both motion and appearance models are estimated, and a probability map is inferred using a Bayesian filtering framework. Finally, Multi-label Graph-cut on Markov Random Field is employed to perform pixel-wise labeling. Extensive evaluation results show that the proposed method outperforms state-of-the-art methods on challenging video sequences.
PS1/γ-Secretase-Mediated Cadherin Cleavage Induces β-Catenin Nuclear Translocation and Osteogenic Differentiation of Human Bone Marrow Stromal Cells

Bone marrow stromal cells (BMSCs) are considered a promising tool for bone bioengineering. However, the mechanisms controlling osteoblastic commitment are still unclear. Osteogenic differentiation of BMSCs requires the activation of β-catenin signaling, classically known to be regulated by the canonical Wnt pathway. However, BMSCs treatment with canonical Wnts in vitro does not always result in osteogenic differentiation and evidence indicates that a more complex signaling pathway, involving cadherins, would be required to induce β-catenin signaling in these cells. Here we showed that Wnt3a alone did not induce TCF activation in BMSCs, maintaining the cells at a proliferative state. On the other hand, we verified that, upon BMSCs osteoinduction with dexamethasone, cadherins were cleaved by the PS1/γ-secretase complex at the plasma membrane, and this event was associated with an enhanced β-catenin translocation to the nucleus and signaling. When PS1/γ-secretase activity was inhibited, the osteogenic process was impaired. Altogether, we provide evidence that PS1/γ-secretase-mediated cadherin cleavage has as an important role in controlling β-catenin signaling during the onset of BMSCs osteogenic differentiation, as part of a complex signaling pathway responsible for cell fate decision. A comprehensive map of these pathways might contribute to the development of strategies to improve bone repair.
Nipple Discharge: Surgical Significance

Nipple discharge is an important clinical entity ranking second only to a lump as the most common complaint among 7,588 patients having breast surgery (560/7,588, or 7.4%). In the office and clinic it is even more common, since many patients can be treated medically and do not require an operation. To be significant, a discharge should be true, spontaneous, persistent, and nonlactational. Nipple discharge can be milky, multicolored and sticky, purulent, clear (watery), yellow (serous), pink (serosanguineous), or bloody (sanguineous). Watery, serous, serosanguineous, and sanguineous discharges are surgically significant; while they are most often caused by intraductal papillomas or fibrocystic disease, they can be due to cancer or a precancerous mastopathy. Among 503 patients operated on for one of these types of discharge, 67 (13.3%) had cancer, and 36 (7.2%) had a precancerous mastopathy. Among the 67 patients with cancer, eight (11.9%) had no palpable mass, 11 (16.4%) had negative cytologic findings, and seven (10.4%) had a negative mammogram. The incidence of associated cancers increases when the discharge is, in order of increasing frequency, serous, serosanguineous, sanguineous, or watery, when it is accompanied by a lump, when it is unilateral and from a single duct, when there are positive cytologic or mammographic findings, and when the patient is more than 50 years of age. Milky discharge caused by galactorrhea is treated medically except when caused by a pituitary adenoma. Multicolored sticky discharge due to duct ectasia is also treated medically except in advanced cases. Purulent discharge caused by an abscess requires drainage and a biopsy of the abscess wall. Except in women less than 30 years of age or in those anxious to have children, we advise a complete central duct excision for patients with surgically significant types of discharge. If done carefully, this procedure can yield good cosmetic results.
Computing the set of concepts through the composition and decomposition of formal contexts

This paper studies the computation of concepts through the composition and decomposition of formal contexts. Under the cases of apposition and subposition, the paper proposes the composition theory to obtain the concepts of the original contexts from its subcontexts and proposes decomposition theory to obtain the concepts of subcontexts from the original context Finally, the composition and decomposition theories are generalized to situations of apposition and subposition involving n(≥ 3) contexts.
Problèmes inverses en diffusion thermique - Formulation et résolution du problème des moindres carrés

La mise en place du critere a minimiser, qui est a la base de la resolution de tout probleme inverse, est introduite. Le cas de l’inversion de mesures a l’aide d’un modele lineaire est traite. L’etude de son aspect eventuellement « mal-pose », l’estimateur des moindres carres ordinaires et sa matrice de variance-covariance sont presentes. Les differentes techniques d’inversion de mesures au moyen d’un modele non lineaire sont ensuite detaillees. Des exemples d’inversion en conduction stationnaire ou non, sont traites, en partant de simulations de mesure integrant un bruit. L’explosion des estimations, en cas de mauvais conditionnement de la matrice de sensibilite, est mise en evidence.
Degradation of 1,4-dichlorobenzene by Xanthobacter flavus 14p1

Xanthobacter flavus 14p1 was isolated from sludge of the river Mulde by selective enrichment with 1,4-dichlorobenzene as the sole source of carbon and energy. The bacterium did not use other aromatic or chloroaromatic compounds as growth substrates. During growth on 1,4-dichlorobenzene, stoichiometric amounts of chloride ions were released. Degradation products of 1,4-dichlorobenzene were identified by gas chromatography-mass spectrometry analysis. 3,6-Dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene and 3,6-dichlorocatechol were isolated from culture fluid. 2,5-Dichloromuconic acid and 2-chloromaleylacetic acid as well as the decarboxylation product 2-chloroacetoacrylic acid were identified after enzymatic conversion of 3,6-dichlorocatechol by cell extract. 1,4-Dichlorobenzene dioxygenase, dihydrodiol dehydrogenase, and catechol 1,2-dioxygenase activity were induced in cells grown on 1,4-dichlorobenzene. The results demonstrate that 1,4-dichlorobenzene degradation is initiated by dioxygenation and that ring opening proceeds via ortho cleavage.