Miracle-dz/UniFAR-FTUs huggingface dataset:
Face Recognition-Aided IPTV Group Recommender with Consideration of Serendipity

 Abstract—The internet protocol television (IPTV) provide thousands of video contents to the users. However, it is difficult to each user to make selection from the amount of videos especially for the group of users. For dealing with the problem, the recommendation systems are developed to aid the users to make selection. In this study, the group recommender named " EyeTV " is proposed which is a multi-facial recognition technique-aided IPTV system, and it is an improved version of the 1 st generation proposed in 2012. The EyeTV system applies Microsoft Xbox's IP camera-KINECT to be the eye of TV for capturing facial features of users, and the multi-facial recognition technique is employed to recognize the user's identity. The users who watch the videos together are taken as a group, and then the system would memorize the watching history for that group automatically. The interactions among the group members can be predicted by the recommendation algorithm of EyeTV, that is, the recommended results are taken the members' interactions into consideration, and the recommended results may be more and more relevant to the group after training. However, the members may be able to guess what kinds of videos would be recommended to them at the time, and the group recommender can be considered as an ineffective service. For preventing the problem mentioned before and providing the group members new watching experience, the social network-based serendipity recommender is employed to improve the EyeTV system. The improved EyeTV system takes the recorded information from the social network of each member, and the data from social network would be combined with the group's watching history for providing serendipitous recommendations to the group.
Controlled start-up stochastic decoding of LDPC codes

This paper concerns a new and powerful Low-Density Parity-Check (LDPC) stochastic decoding algorithm, called Controlled Start-up Stochastic (CSS) decoding, to implement fully parallel LDPC decoders. The proposed algorithm uses a clever starting point computing method to improve the convergence as well as to reduce the latency of the decoding process, without a significant hardware complexity cost. Using this stochastic method, in low signal-to-noise ratio (SNR) region, a short LDPC code can outperforms the fixed point state-of-the-art (2048, 1723) LDPC code. To validate the performance of the proposed algorithm, a (48, 24) LDPC code are implemented on Xilinx Virtex-6 VLX240T field programmable gate array device, with and without the CSS method. The new algorithm provides a decoding speed seven times faster and a Bit Error Rate (BER) hundred times better at E3/N0=4.5 dB. In addition, the results provide a BER better than the 6 bits offset min-sum algorithm (OMSA) and better than the 6 bits sum-product algorithm (SPA) for the (2048, 1723) LDPC code, below E3/N0=3.9 dB and Eb/N0=4.3 dB respectively. The obtained results show that, the proposed algorithm is the first stochastic algorithm which can outperform the OMSA and SPA algorithms, with less hardware complexity.
Baculoviral delivery of CRISPR/Cas9 facilitates efficient genome editing in human cells

The CRISPR/Cas9 system is a highly effective tool for genome editing. Key to robust genome editing is the efficient delivery of the CRISPR/Cas9 machinery. Viral delivery systems are efficient vehicles for the transduction of foreign genes but commonly used viral vectors suffer from a limited capacity in the genetic information they can carry. Baculovirus however is capable of carrying large exogenous DNA fragments. Here we investigate the use of baculoviral vectors as a delivery vehicle for CRISPR/Cas9 based genome-editing tools. We demonstrate transduction of a panel of cell lines with Cas9 and an sgRNA sequence, which results in efficient knockout of all four targeted subunits of the chromosomal passenger complex (CPC). We further show that introduction of a homology directed repair template into the same CRISPR/Cas9 baculovirus facilitates introduction of specific point mutations and endogenous gene tags. Tagging of the CPC recruitment factor Haspin with the fluorescent reporter YFP allowed us to study its native localization as well as recruitment to the cohesin subunit Pds5B.
The DCU Dependency-Based Metric in WMT-MetricsMATR 2010

We describe DCU's LFG dependency-based metric submitted to the shared evaluation task of WMT-MetricsMATR 2010. The metric is built on the LFG F-structure-based approach presented in (Owczarzak et al., 2007). We explore the following improvements on the original metric: 1) we replace the in-house LFG parser with an open source dependency parser that directly parses strings into LFG dependencies; 2) we add a stemming module and unigram paraphrases to strengthen the aligner; 3) we introduce a chunk penalty following the practice of METEOR to reward continuous matches; and 4) we introduce and tune parameters to maximize the correlation with human judgement. Experiments show that these enhancements improve the dependency-based metric's correlation with human judgement.
DegranulationTheir Ability to Trigger NK Cell Expression on Multiple Myeloma Cells and MHC Class I-Related Chain A and B Ligand Heat Shock Protein-90 Inhibitors Increase

Modulation of the host immune system represents a promising therapeutic approach against cancer, including multiple myeloma. Recent ﬁndings indicate that the NK group 2D (NKG2D)- and DNAX accessory molecule-1 (DNAM-1)-activating receptors play a prominent role in tumor recognition and elimination by cytotoxic lymphocytes, suggesting that the levels of NKG2D and DNAM-1 ligand expression on tumor cells may be a critical factor to improve the immune response against cancer. In this study, we tested the effect of 17-allylaminogeldanamycin and radicicol, drugs targeting the heat shock protein-90 (HSP-90) chaperone protein and displaying antimyeloma activity, on the expression of NKG2D and DNAM-1 ligands in human myeloma cell lines. We demonstrate that HSP-90 inhibitors are able to up-regulate both MHC class I chain-related (MIC) A and MICB protein surface and mRNA expression in human myeloma cell lines, without any signiﬁcant effect on the basal expression of the DNAM-1 ligand poliovirus receptor CD155, or induction of nectin-2 and UL16-binding proteins. Activation of the transcription factor heat shock factor-1 by HSP-90 inhibitors is essential for the up-regulation of MICA/MICB expression and knockdown of heat shock factor-1 using small hairpin RNA interference blocks this effect. Moreover, in vitro and in vivo binding of heat shock factor-1 to MICA and MICB promoters indicates that it may enhance NKG2D ligand expression at the transcriptional level. Finally, exposure to HSP-90 inhibitors renders myeloma cells more efﬁcient to activate NK cell degranulation and a blocking Ab speciﬁc for NKG2D signiﬁcantly reduces this effect. Thus, these results
Ack1: Activation and Regulation by Allostery

The non-receptor tyrosine kinase Ack1 belongs to a unique multi-domain protein kinase family, Ack. Ack is the only family of SH3 domain containing kinases to have an SH3 domain following the kinase domain; others have their SH3 domains preceding the kinase domain. Previous reports have suggested that Ack1 does not require phosphorylation for activation and the enzyme activity of the isolated kinase domain is low relative to other kinases. It has been shown to dimerize in the cellular environment, which augments its enzyme activity. The molecular mechanism of activation, however, remains unknown. Here we present structural and biochemical data on Ack1 kinase domain, and kinase domain+SH3 domain that suggest that Ack1 in its monomeric state is autoinhibited, like EGFR and CDK. The activation of the kinase domain may require N-lobe mediated symmetric dimerization, which may be facilitated by the N-terminal SAM domain. Results presented here show that SH3 domain, unlike in Src family tyrosine kinases, does not directly control the activation state of the enzyme. Instead we speculate that the SH3 domain may play a regulatory role by facilitating binding of the MIG6 homologous region to the kinase domain. We postulate that features of Ack1 activation and regulation parallel those of receptor tyrosine kinase EGFR with some interesting differences.
Contact lenses in the emergency room

Eight hospitals in the Portland, Oregon Metropolitan area were surveyed with respect to techniques utilized by emergency room personnel in identifying patients wearing contact lenses and the subsequent removal and storage of these lenses. Hospital sizes ranged from 48 beds to 554 beds. In general, the results indicated that the single weak area in lens detection, removal, and storage for hard and soft lenses, is the lack of information with respect to soft lens storage solutions. Appropriate soft lens storage procedures were not known by all hospitals. Emergency room directors of smaller hospitals stated however that few, if any, individuals wearing contact lenses (hard or soft) were seen in an emergency room setting. Results of the survey also found that having cants.ct lens wearers be identified as such on their driver's license would not necessarily facilitate operations of the emergency room personnel since law officials at the accident site often temporarily kept these driver's licenses.
Observations of planetary waves in the mesosphere-lower thermosphere during stratospheric warming events

Abstract. This study investigates the effect of stratospheric sudden warmings (SSWs) on planetary wave (PW) activity in the mesosphere–lower thermosphere (MLT). PW activity near 95 km is derived from meteor wind data using a chain of eight SuperDARN radars at high northern latitudes that span longitudes from 150° W to 25° E and latitudes from 51 to 66° N. Zonal wave number 1 and 2 components were extracted from the meridional wind for the years 2000–2008. The observed wintertime PW activity shows common features associated with the stratospheric wind reversals and the accompanying stratospheric warming events. Onset dates for seven SSW events accompanied by an elevated stratopause (ES) were identified during this time period using the Specified Dynamics Whole Atmosphere Community Climate Model (SD-WACCM). For the seven events, a significant enhancement in wave number 1 and 2 PW amplitudes near 95 km was found to occur after the wind reversed at 50 km, with amplitudes maximizing approximately 5 days after the onset of the wind reversal. This PW enhancement in the MLT after the event was confirmed using SD-WACCM. When all cases of polar cap wind reversals at 50 km were considered, a significant, albeit moderate, correlation of 0.4 was found between PW amplitudes near 95 km and westward polar-cap stratospheric winds at 50 km, with the maximum correlation occurring ∼ 3 days after the maximum westward wind. These results indicate that the enhancement of PW amplitudes near 95 km is a common feature of SSWs irrespective of the strength of the wind reversal.
SLA: A Stage-Level Latency Analysisfor Real-Time Communicationin a Pipelined Resource Model

We present a communication analysis for hard real-time systems interconnects. The objective is to provide tight estimates on the worst-case communication latency between communicating processing elements that use a priority-aware communication medium for data transmission. The communication model consists of communication tasks transmitting data across a series of pipelined resources. The analysis incorporates interferences caused by multiple communication tasks requesting the pipelined resources, and it captures parallel transmission of data between multiple pipeline stages. We call this analysis a stage-level analysis. We evaluate the proposed analysis through simulation of synthetic benchmarks, and we apply the analysis to an instantiation of a platform proposed by Shi and Burns. Our experiments confirm that stage-level analysis provides tight upper-bounds when compared to previous work and improves schedulability by 34 percent.
Recovery and Characterization of a Minute Virus of Canines

Four antigenically related transmissible agents were recovered from canine fecal specimens. The agents produced cytopathic effects in a continuous dog cell line developed in this laboratory. Increased antibody titers were demonstrated in three of the four dogs which provided the isolates. The virus did not produce cytopathic effects in primary canine kidney or thymus cell cultures, or in cell cultures of human, simian, porcine, bovine, feline, and murine origin. The agent is resistant to ether, chloroform, and heat treatment, and the growth of the virus is inhibited by 5-iodo-2-deoxyuridine. After acridine orange staining, green fluorescent intranuclear inclusions are seen in infected cell cultures. By electron microscopy, the virions measure approximately 20 to 21 nm in overall diameter and are present in the nuclei of infected cells. These properties are consistent with membership in the parvovirus or picodnavirus group. The agent hemagglutinates rhesus red blood cells at 5 C and by hemagglutination-inhibition tests could be readily distinguished from H-1, rat virus, and the minute virus of mice. Canine gamma globulin contains high titers of neutralizing antibody and neutralizing antibody was found in a high percentage of military dogs and in beagles of a breeding colony.
Identifiability of Path-Specific Effects

Counterfactual quantities representing path-specific effects arise in cases where we are interested in computing the effect of one variable on another only along certain causal paths in the graph (in other words by excluding a set of edges from consideration). A recent paper [Pearl, 2001] details a method by which such an exclusion can be specified formally by fixing the value of the parent node of each excluded edge. In this paper we derive simple, graphical conditions for experimental identifiability of path-specific effects, namely, conditions under which path-specific effects can be estimated consistently from data obtained from controlled experiments.
Predictors of success of medical management of ectopic pregnancy in a tertiary care hospital in United arab emirates.

INTRODUCTION Ectopic pregnancy is the most common cause of pregnancy related deaths in the first trimester of pregnancy. Advances in laboratory and imaging technologies in last few decades allow an early diagnosis of ectopic pregnancy, many times even before the patient develops any symptoms. Consequently in many such patients surgery is not always necessary. Expectant and medical management are feasible options in properly selected cases. In the present study, efficacy of medical management of selected cases of ectopic pregnancy with injection methotrexate and the factors influencing the success of medical management were evaluated. MATERIALS AND METHODS Retrospective study involving 40 women with ectopic pregnancy who met inclusion criteria and were managed medically with Methotrexate (MTX) in a tertiary hospital in United Arab Emirates (UAE). Various factors which could possibly influence the success of medical management were evaluated. RESULTS ROC analyses for day 1(pretreatment) Beta HCG levels revealed that the optimum cut off for Beta HCG level of 6000 mIU/ml on day 1 can be considered a good predictor of success of medical management with MTX. Falling serum Beta HCG between day 1-4 very well predicted success of MTX therapy (irrespective of number of doses of MTX) with a positive predictive value (PPV) of 100% and negative predictive value (NPV) of 31.25%. Similarly adnexal mass size ≤ 3 cms and duration of amenorrhoea < 6 weeks were found to be good predictors of success of medical management (PPV 96.66% and NPV 90% for both factors). In the present study, irrespective of number of doses received, medical management with MTX was successful in 75% cases (30 out of 40). CONCLUSION RESULTS of this study indicate that pretreatment Beta HCG level of < 6000 mIU/ml, adnexal mass size < 3 cms, amenorrhoea < 6 weeks and absence of free fluid in the pelvis are predictors of a successful treatment with MTX. In properly selected cases medical management of ectopic pregnancy with MTX is highly effective and can be considered a forward step taken towards conservation of fallopian tubes especially in countries like UAE where there is inclination towards large family size based on religious and cultural background.
A Supervised Algorithm for Verb Disambiguation into VerbNet Classes

VerbNet (VN) is a major large-scale English verb lexicon. Mapping verb instances to their VN classes has been proven useful for several NLP tasks. However, verbs are polysemous with respect to their VN classes. We introduce a novel supervised learning model for mapping verb instances to VN classes, using rich syntactic features and class membership constraints. We evaluate the algorithm in both in-domain and corpus adaptation scenarios. In both cases, we use the manually tagged Semlink WSJ corpus as training data. For indomain (testing on Semlink WSJ data), we achieve 95.9% accuracy, 35.1% error reduction (ER) over a strong baseline. For adaptation, we test on the GENIA corpus and achieve 72.4% accuracy with 10.7% ER. This is the first large-scale experimentation with automatic algorithms for this task.
The Effect of Incentive Schemes and Organizational Arrangements on the New Product Development Process

This paper proposes a new model for studying the new product development process in an artificial environment. We show how connectionist models can be used to simulate the adaptive nature of agents' learning exhibiting similar behavior as practically experienced learning curves. We study the impact of incentive schemes (local, hybrid, and global) on the new product development process for different types of organizations. Sequential organizational structures are compared to two different types of team-based organizations, incorporating methods of quality function deployment such as the house of quality. A key finding of this analysis is that the firms' organizational structure and agents' incentive system significantly interact. We show that the house of quality is less affected by the incentive scheme than firms using a trial and error approach. This becomes an important factor for new product success when the agents' performance measures are conflicting.
Optimal control of systems with resource constraints

In this paper optimal control of systems with constrained computation and communication resources is studied. The timing of real-time scheduling algorithms like rate monotonic scheduling and earliest deadline first scheduling is analyzed. It is shown that these scheduling algorithms lead to periodically varying sampling periods and time delays. Modeling of the resulting periodically time-varying systems is described and based on this, the design of a periodic linear quadratic regulator is presented. Applying the lifting technique, a time-invariant reformulation of the design problem is obtained. The regulator gains result from solving algebraic Riccati equations. To further improve control performance, a method which combines offline-scheduling and periodic control is proposed. The methods are illustrated by an example.
Deficits in Motor Response to Avoid Sudden Obstacles During Gait in Functional Walkers Poststroke

Background. Safe community ambulation requires the capacity to adapt gait to environmental changes on short notice. Reduced adaptability may contribute to an increased risk for falls. Objective. This study investigated gait adaptability in community-dwelling persons poststroke and sought to understand some of the mechanisms of reduced adaptability. Methods. Participants were 25 poststroke persons (Functional Ambulation Categories score 5) and 25 healthy controls of similar age. During treadmill walking, 30 obstacles were suddenly dropped in front of the affected leg or left leg of controls. The participants had to avoid the obstacle by either lengthening or shortening the ongoing stride. The obstacle avoidance success rates were determined. Electromyography activity of bilateral biceps femoris, rectus femoris, tibialis anterior, and gastrocnemius medialis muscles was recorded as well as concomitant knee and hip angle courses and spatial characteristics of the avoiding stride. Results. Poststroke persons demonstrated markedly decreased obstacle avoidance success rates, most prominently under time pressure. They showed normal avoidance strategies but had delayed and reduced electromyography responses, smaller joint angle deviations from unperturbed walking, and smaller horizontal margins from the foot to the obstacle. Conclusions. Even in persons who were only mildly affected by stroke, gait adaptability may be reduced, which may place them at risk of falling. Delayed and decreased muscle responses were identified as one possible mechanism with diminished ability to adapt the length of the avoiding stride. Rehabilitation interventions could focus on these impairments.
The syndemogenesis of depression

Syndemics, or the deleterious interaction of diseases and structural factors, is an essential and increasingly utilized theory with which to address health inequities and how they interact with disease. However, less research has been conducted on syndemogenesis, a process by which a specific disease or structural factor is more likely to exacerbate syndemic interactions. With the increasing incidence and prevalence of depressive symptomology in Westernized nations, and with depression coexisting syndemically with other illnesses, I use depression as a case study to highlight syndemogenic processes in action. Doing so will hopefully aid preventive efforts in these areas.
New insight into onset of lactation: mediating the negative effect of multiple perinatal biopsychosocial stress on breastfeeding duration.

BACKGROUND Many perinatal stressors, including high prepregnancy body mass index, preterm birth, and cesarean section, increase the risk for short breastfeeding duration. Few studies, however, have investigated the mechanism in the relationship between perinatal determinants and breastfeeding duration. This study aimed to test the hypothesis that delayed onset of lactation (OL) could mediate the negative effect of perinatal biopsychosocial stress on breastfeeding duration and to evaluate the impact of new perinatal factors with potentially hazardous effects. SUBJECTS AND METHODS Maternal demographic characteristics, health status, and psychological stress during pregnancy were assessed by structured questionnaires and medical records. The information of lactation was collected in the hospital within 1-3 days after delivery. Data on breastfeeding behaviors were obtained through the telephone interview at 2 months after delivery. RESULTS The risk of delayed OL increased in women who had experienced severe life event stress in the first trimester of pregnancy (adjusted risk ratio [RR] 2.59, 95% confidence interval [CI] 1.52, 4.40), had undergone cesarean section (adjusted RR 2.11, 95% CI 1.46, 3.05), whose gestational body mass index gain were not less than 7.62 (adjusted RR 1.90, 95% CI 1.27, 2.86), and whose breastfeeding frequency was less than three times in the first day after childbirth (adjusted RR 2.14, 95% CI 1.57, 2.91). The final model of structural equation modeling indicated that women with cesarean section, preterm birth, greater gestational body mass index gain, higher scores of stressful life events in the first trimester, and less breastfeeding frequency in the first day after delivery were more likely to experience delayed OL, which could result in an earlier breastfeeding termination. CONCLUSIONS Delayed OL, as a negative biological event resulted from the perinatal biopsychosocial stress, is a key mediator linking perinatal factors to breastfeeding duration. More attention should to be paid to underweight before pregnancy and severe life events during pregnancy, which are regarded as novel and remarkable risk factors of delayed OL and short breastfeeding duration.