Miracle-dz/UniFAR-FTUs huggingface dataset:
Publish/Subscribe in a Mobile Environment

A publish/subscribe system dynamically routes and delivers events from sources to interested users, and is an extremely useful communication service when it is not clear in advance who needs what information. In this paper we discuss how a publish/subscribe system can be extended to operate in a mobile environment, where events can be generated by moving sensors or users, and subscribers can request delivery at handheld and/or mobile devices. We describe how the publish/subscribe system itself can be distributed across multiple (possibly mobile) computers to distribute load, and how the system can be replicated to cope with failures, message loss, and disconnections.
Relative size and complexity: e-business use in small and medium sized tourism enterprises in Thailand

Purpose – The research documented in this paper aims to explore e‐business uses in small and medium‐sized tourism enterprises compared with their larger counterparts.Design/methodology/approach – Five case studies were conducted with Thai tourism SMEs to investigate their technology adoption and use experiences. For large‐sized enterprises, an extensive review of industry's practice was conducted. A comparison was then carried out based on the scope of the technology, namely inter‐organisation, intra‐organisation, and front‐end side linking to customers.Findings – In terms of e‐business use, it is not surprising that Thai SMEs remain less advanced in utilising e‐business technology. However, size is found to be a significant factor in determining SME behaviour not only in comparison to larger travel agencies or hotels, but also with the SME sector itself. Associated with this is application complexity that is again significant and linked to relative size. Finally, the choices made by small hotels and trav.
Evolution and the Biosynthesis of Ascorbic Acid

The ability to synthesize ascorbic acid is absent in the insects, invertebrates, and fishes. The biosynthetic capacity started in the kidney of amphibians, resided in the kidney of reptiles, became transferred to the liver of mammals, and finally disappeared from the guinea pig, the flying mammals, monkey, and man. A similar transition in the biosynthetic ability was observed in the branched evolution of the birds.
Spatio-temporal steerable pyramid for human action recognition

In this paper, we propose a novel holistic representation based on the spatio-temporal steerable pyramid (STSP) for human action recognition. The spatio-temporal Laplacian pyramid provides an effective technique for multi-scale analysis of video sequences. By decomposing spatio-temporal volumes into band-passed sub-volumes, spatio-temporal patterns residing in different scales will be nicely localized. Then three-dimensional separable steerable filters are conducted on each of the sub-volume to capture the spatio-temporal orientation information efficiently. The outputs of the quadrature pair of steerable filters are squared and summed to yield a more robust measure of motion energy. To make the representation invariant to shifting and applicable with coarsely-extracted bounding boxes for the performed actions, max pooling operations are employed between responses of the filtering at adjacent scales, and over spatio-temporal local neighborhoods. Taking advantage of multi-scale and multi-orientation analysis and feature pooling, STSP produces a compact but informative and invariant representation of human actions. We conduct extensive experiments on the KTH, IXMAS and HMDB51 datasets, and the proposed STSP achieves comparable results with the state-of-the-art methods.
A Neural Network Based Extraction of Salient Regions by Segmenting Color Images

Due to the advent of computer technology image-processing techniques have become increasingly important in a wide variety of applications. This is particularly true for medical imaging such as Computer Tomography (CT), magnetic resonance image (MRI), and nuclear medicine, which can be used to assist doctors in diagnosis, treatment, and research This paper presents a novel method to extract salient regions in images using low-level features of luminance and color. The method is fast, easy to implement and generates high quality saliency maps of the same size and resolution as that of the input image. The novelty of our approach lies in finding high quality saliency maps of the same size and resolution as the input image and their use in segmenting whole objects.
The role of disgust in patients with hypochondriasis

Theoretically, disgust sensitivity and disgust proneness could play an important role in hypochondriasis, since disgust is a defensive emotion widely believed to protect the organism from illness. However, empirical evidence to support this hypothesis has so far been based only on nonclinical samples, so that the importance and specificity of disgust for hypochondriasis remains unclear. In the current study, 36 patients with hypochondriasis, 27 with an anxiety disorder, and 29 healthy controls completed several measures which included the assessment of disgust sensitivity (Scale for the Assessment of Disgust Sensitivity) and disgust proneness (Questionnaire for the Assessment of Disgust Proneness). We found that patients with hypochondriasis and those with an anxiety disorder had higher scores than those of the healthy controls for several measures of disgust proneness. Moreover, measures of hypochondriacal characteristics were associated with those of disgust proneness and disgust sensitivity. However, no differences were found between patients with hypochondriasis and those with anxiety disorders, with respect to disgust proneness and disgust sensitivity. Therefore, it can be assumed that disgust proneness and disgust sensitivity seem to be less specific than previously suggested for the development and maintenance of hypochondriasis.
Sounds of Silence: The Translation of Women’s Voices from Marie de France to the Old Norse Strengleikar

Secundum quidem quod in principio Genesis loquitur, ubi de primordio mundi Sacratissima Scriptura pertractat, mulierem invenitur ante omnes fuisse locutam, scilicet presumptuosissimam Evam, cum dyabolo sciscitanti respondit. Sed quanquam mulier in scriptis prius inveniatur locuta, rationabilius tamen est ut hominem prius locutum fuisse credamus, et inconvenienter putatur tam egregium humani generis actum non prius a viro quam a femina profluxisse. Rationabiliter ergo credimus ipsi Ade prius datum fuisse loqui ab Eo qui statim ipsum plasmaverat.
Enhanced Pedigree Error Detection

Accurate information on the relationships among individuals in a study is critical for valid linkage analysis. We extend the MLLR, EIBD, AIBS and IBS tests for detection of misspecified relationships to a broader range of relative pairs, and we improve the two-stage screening procedure for analyzing large data sets. We have developed software, PREST, which calculates the test statistics and performs the corresponding hypothesis tests for relationship misclassification in general outbred pedigrees. When a potential pedigree error is detected, our companion program, ALTERTEST, can be used to determine which relationships are compatible with the genotype data. Both programs are now freely available on the web.
A 1V RF SoC with an 863-to-928MHz 400kb/s radio and a 32b Dual-MAC DSP core for Wireless Sensor and Body Networks

A 150¿A/MHz DSP with two MAC/cycle instructions is integrated with a configurable 863-to-928MHz RF transceiver that yields 3.5mW in continuous reception, 2¿C per channel sampling and 40mW for 10dBm output. The SoC includes voltage converters that allow 1.0-to-1.8V or 2.7-to-3.6V primary voltage supplies. In sleep mode, it consumes 1¿A with a 32kHz crystal-based RTC running.
Demography at the Edge: Remote Human Populations in Developed Nations

Addressing the methodological and topical challenges facing demographers working in remote regions, this book compares and contrasts the research, methods and models, and policy applications from peripheral regions in developed nations. With the emphasis on human populations as dynamic, adaptive, evolving systems, it explores how populations respond in different ways to changing environmental, cultural and economic conditions and how effectively they manage these change processes. Theoretical understandings and policy issues arising from demographic modelling are tackled including: competition for skilled workers; urbanisation and ruralisation; population ageing; the impacts of climate change; the life outcomes of Indigenous peoples; globalisation and international migration. Based on a strong theoretical framework around issues of heterogeneity, generational change, temporariness and the relative strength of internal and external ties, Demography at the Edge provides a common set of approaches and issues that benefit both researchers and practitioners.
Biodegradable ionic liquids: Part I. Concept, preliminary targets and evaluation

The design, preparation and evaluation of biodegradable ionic liquids containing ester or amide groups in the alkyl side chain are presented. Factors improving the biodegradation of surfactants were successfully applied to ionic liquids. These novel ionic liquids can be prepared from readily available starting materials in high yield. The introduction of a group susceptible to enzymatic hydrolysis greatly improves the biodegradation (OECD 301D ‘Closed Bottle Test’) compared with the commonly used dialkylimidazolium ionic liquids, bmimBF4 and bmimPF6. For the 3-methyl-1-(alkyloxycarbonylmethyl)imidazolium bromide series, the greatest biodegradation was observed when alkyl = butyl, pentyl, hexyl and octyl. The corresponding amide analogs proved to be poorly biodegradable.
Advantages of InGaN Light Emitting Diodes With Alternating Quantum Barriers

InGaN light-emitting diodes (LEDs) with the alternating quantum barriers (AQB) of AlGaN and InGaN is proposed for LED applications. With this design, simulation results show that the carrier concentration and transport in the multi-quantum well (MQW) active region are improved and accordingly, the radiative recombination rate is enhanced and the electron leakage is suppressed, due to the appropriate band engineering. Thus, the proposed structure shows an efficient improvement in the internal quantum efficiency (IQE) and efficiency droop, compared to the original structures with GaN barriers, or AlGaN barriers, or InGaN barriers. Our studies suggest that relatively simple engineering of the MQW region may still have notable positive effects on LED performance.
Phase I trial of fludarabine, bortezomib and rituximab for relapsed and refractory indolent and mantle cell non‐Hodgkin lymphoma

Based on the hypothesis that bortezomib may potentiate fludarabine activity by inhibiting DNA repair, we designed a phase I trial using this combination with rituximab in patients with relapsed and refractory indolent and mantle cell non‐Hodgkin lymphoma. Twenty‐four patients were enrolled. Non‐Hodgkin lymphoma subtypes included 12 patients with follicular lymphoma, four with marginal zone lymphoma, three with lymphoplasmacytic lymphoma, three with mantle cell lymphoma and two with small lymphocytic/chronic lymphocytic leukaemia. Fludarabine and bortezomib were escalated in cohorts of three patients. Rituximab was added to the maximum tolerated dose of fludarabine and bortezomib and added significant dose‐limiting myelosuppression. The maximum tolerated dose was fludarabine 25 mg/m2 on days 1–3, bortezomib 1·3 mg/m2 on days 1, 4, 8, 11, with rituximab 375 mg/m2 on day 1 administered every 21 d. Clinical responses were observed in 11 patients, five of whom were refractory to their most recent treatment regimen. Six additional patients had stable disease for a median of 10 months (range 4–30+). Cumulative myelosuppression and neuropathy was observed. The combination of fludarabine, bortezomib, and rituximab appears to be an active regimen with manageable toxicity for relapsed NHL.
Mammalian pharmacokinetics of carbon nanotubes using intrinsic near-infrared fluorescence

Individualized, chemically pristine single-walled carbon nanotubes have been intravenously administered to rabbits and monitored through their characteristic near-infrared fluorescence. Spectra indicated that blood proteins displaced the nanotube coating of synthetic surfactant molecules within seconds. The nanotube concentration in the blood serum decreased exponentially with a half-life of 1.0 ± 0.1 h. No adverse effects from low-level nanotube exposure could be detected from behavior or pathological examination. At 24 h after i.v. administration, significant concentrations of nanotubes were found only in the liver. These results demonstrate that debundled single-walled carbon nanotubes are high-contrast near-infrared fluorophores that can be sensitively and selectively tracked in mammalian tissues using optical methods. In addition, the absence of acute toxicity and promising circulation persistence suggest the potential of carbon nanotubes in future pharmaceutical applications.
2-Cyanoanilinium nitrate

In the title compound, C7H7N2 +·NO3 −, all atoms of the cation, with the exception of two H atoms of the NH3 group, lie on a mirror plane, while the anion lies across this plane with the N and one O atom on the mirror plane. In the crystal structure, the organic cations and NO3 − anions are linked by N—H⋯N and N—H⋯O hydrogen bonds, forming a two-dimensional network parallel to (100).
Association of BMI1 with Polycomb Bodies Is Dynamic and Requires PRC2/EZH2 and the Maintenance DNA Methyltransferase DNMT1

ABSTRACT Polycomb group (PcG) proteins are epigenetic chromatin modifiers involved in heritable gene repression. Two main PcG complexes have been characterized. Polycomb repressive complex 2 (PRC2) is thought to be involved in the initiation of gene silencing, whereas Polycomb repressive complex 1 (PRC1) is implicated in the stable maintenance of gene repression. Here, we investigate the kinetic properties of the binding of one of the PRC1 core components, BMI1, with PcG bodies. PcG bodies are unique nuclear structures located on regions of pericentric heterochromatin, found to be the site of accumulation of PcG complexes in different cell lines. We report the presence of at least two kinetically different pools of BMI1, a highly dynamic and a less dynamic fraction, which may reflect BMI1 pools with different binding capacities to these stable heterochromatin domains. Interestingly, PRC2 members EED and EZH2 appear to be essential for BMI1 recruitment to the PcG bodies. Furthermore, we demonstrate that the maintenance DNA methyltransferase DNMT1 is necessary for proper PcG body assembly independent of DNMT-associated histone deacetylase activity. Together, these results provide new insights in the mechanism for regulation of chromatin silencing by PcG proteins and suggest a highly regulated recruitment of PRC1 to chromatin.
Prevalence of Hepatitis B Surface Antigen (HBsAg) Positivity among General Population in Yavatmal (Maharashtra), India

Hepatitis-B virus infection is a life threatening disease and contributes to a large man power as well as economical loss worldwide. It is a serious and common infectious diseases of the liver affecting millions of people worldwide (Meshram et al., 2015). It is caused by hepatitis-B virus which can be transmitted through percutaneous i.e. puncture through the skin and mucosal route i.e. direct contact with mucosal membrane, exposure to infectious blood or blood products, through body fluids. Vertical transmission (from mother to child) of the virus, unsafe sexual intercourse are also important routes for the transmission of the disease (Mohd Akmal et al., 2015).
A three–dimensional model for ciliary motion based on the internal 9 + 2 structure

Here we present, to our knowledge, the first modelling platform that enables simulations of three–dimensional (3D) motion of multicilia arrays at a detailed level. It consists of three building blocks: (i) geometric equations for tracking the 3D motion of the cilia, (ii) a hydrodynamic description of the ciliary system, and (iii) model equations for the internal bend generating based on the 9 + 2 structure. The model generates seemingly realistic 3D beat patterns and demonstrates metachronal coordination that evolves autonomously as a result of the hydrodynamic coupling between the cilia. We study the effect of the twisting motion within the cilia and propose a conjecture on a possible role of the radial spokes system.
eledSQL: a new web-based learning environment for teaching databases and SQL at secondary school level

Data modeling using databases and SQL is a fundamental part of the curriculum of secondary computing education in Germany. Professional database tools like HeidiSQL, phpMyAdmin or Microsoft Access are often used in class as a "learning software", although these tools have been developed for managing complex databases, often for companies, and not for educational purposes. Such tools offer a wide range of functions of which only a small part is required by secondary computing education. At the beginning of such instruction, students can hardly work independently with these programs, as they do not know the database language SQL by then. This often leads to theory-loaded introductory phases of such classes or alternatively to a usage of such tools like spreadsheet programs. To address this problem, a new web-based learning environment for databases and SQL (named eledSQL), also suitable for mobile devices and only with the functionality needed for secondary computing education, was developed. The basic idea was to initially allow students to make database queries using natural language and then gradually introduce them to the use of SQL. Starting with a problem analysis and a discussion of related work in the field of teaching databases and SQL, in this paper the conception of eledSQL, its implementation and first experiences with its practical use are described.
About the possibilities of a new edge definition in black and white images

This research is devoted to the problems in the field of black and white image processing which are connected with the purpose to detect the maximum number of edges and to determine their exact coordinates as far as possible. It is made a critical analysis of the commonly accepted definition of the edge, modeled as a ramp. Consent to this definition there is only an edge which position is in the middle of the ramp connecting low and high level of intensity. Here the authors give a new edge definition, according to it there are two edges (contrary to the classical definition) - one on the low level and a second one - on the high level of intensity. As a result of this understanding the suggested here definition is mathematically formalized by the interrupted first derivative of the intensity function. Based on this definition authors work up an edge detector achieving sub-pixel accuracy when detects edge points' coordinates. There are synthesized appropriate test images and some of the well known edge detectors and the here suggested are applied to them. Results confirm authors' expectations for accuracy of localization and high informativity in the description of the objects in black and white images, which comes very close to their visual susceptibility
Development of nuclear and chloroplast microsatellite markers for the endangered conifer Callitris sulcata (Cupressaceae)

Premise of the study: Microsatellite markers were developed for Callitris sulcata (Cupressaceae), an endangered conifer species in New Caledonia. Methods and Results: Using sequencing by synthesis (SBS) of an RNA-Seq library, 15 polymorphic nuclear and chloroplast microsatellite markers were developed. When evaluated with 48 individuals, these markers showed genetic variations ranging from two to 15 alleles and expected heterozygosity ranging from 0 to 0.881. Conclusions: These markers will be useful for examining the genetic diversity and structure of remaining wild populations and improving the genetic status of ex situ populations.
HIGH PERFORMANCE LUBRICANTS FOR DEMANDING PM APPLICATIONS

The achievement of high density at reasonable cost is without a doubt one of the major quests of the P/M industry. High density can be achieved through various processing routes involving the shaping of the part and/or the sintering. In particular, single pressing methods such as warm compaction and die wall lubrication are known to give green density in the range of 7.2 to 7.5 g/cm3 depending on the powder formulation. Nevertheless, these pressing techniques normally require tighter control, are costly and may reduce productivity compared to conventional pressing method. More recently, new high performance lubricants were developed to achieve higher green density than conventional lubricant by cold compaction or temperature-controlled die compaction. This paper presents the green and sintered characteristics of these newly developed high performance lubricants in a laboratory and production scale. In particular, the compaction and ejection characteristics of these new lubricants are compared to that obtained with other conventional lubricants.
Using Inductive Learning to Predict Bankruptcy

An emerging trend in organizational computing is using information technology to learn decision knowledge from enterprise data. The primary contribution of this study is the presentation of a sound theory and a comprehensive technique for learning the decision model for predicting bankruptcy. The theory is based on the information contained in cash flow components, which is the foundation of valuation theory, and an analytical system that measures the amount of uncertainty in the cash flow information. The approach links a tree-based inductive learning system that relies on the concept of entropy, with an information system based on the cash flow of a firm. A test of the cash flow approach involves the cash flow components for a sample of 99 failed and 99 non-failed companies. The structural instability of cash flow components generated by an inductive learning system is a serious issue for financial analysts. However, this shortcoming is overcome by using a jackknife procedure to develop a global tree that identifies the most important cash flow components. The final global tree found only 3 cash flow components were needed to classify correctly 89% of the companies as either failed or non-failed. Only a few early studies achieved a higher level of predictive accuracy. The 3 significant cash flow components were dividends, net investment, and net operating cash flow. Using the same data, a probit statistical technique generated a 67.5% predictive accuracy. In summary, the inductive learning results indicate that cash flow components are not only a natural tool for explaining the bankruptcy process, but they provide a high level of predictive accuracy.
Effects of Right and Left Unilateral Ect on Naming and Visual Discrimination Analysed in Relation to Handedness

The use of unilateral ECT as a method of exploring differences between the functions of the cerebral hemispheres has been suggested by Pratt et al. (1971). These authors found a greater impairment on a test of naming and a tendency to slower return to consciousness after left-sided than after right-sided treatments. Assuming that these effects depend on left hemisphere language specialization, they went on to use them as possible indicators of cerebral dominance for speech in left handers. The present enquiry was designed to explore these differences further by comparing patients immediately after right-sided and left-sided ECT for their ability to name objects and to make visual discriminations and for their time of recovery. Handedness was assessed through a measure of relative manual speed as well as by the usual questions of preference and family handedness. The speed differences give a continuous measure of degrees of right and left handedness which can be correlated with measures of differences between the effects of right-sided and left-sided ECT.