Miracle-dz/UniFAR-FTUs huggingface dataset:
The relationship between transformational leadership, task performance and job characteristics

Purpose – The purpose of this paper is to study the relationship between transformational leadership, task performance and perceived measures of job characteristics in French firms. Design/methodology/approach – A questionnaire survey was sent to employees working in the industry and service sectors. A sample of 100 respondents was collected. Findings – The results of the study show that there is a partial relationship between transformational leadership and follower task performance on one hand and, between transformational leadership and follower perceptions of core job characteristics on another hand. Research limitations/implications – The majority of the firms are big ones. Hence, we recommend that our findings be replicated across a sample of firms where small, medium and big ones are presented proportionally. Also, transformational leadership, job characteristics and task performance measures exhibited restrictions in that they depend on the perception of employees and leaders. Practical implicatio.
MobiCloud: Building Secure Cloud Framework for Mobile Computing and Communication

Cloud services can greatly enhance the computing capability of mobile devices. Mobile users can rely on the cloud to perform computationally intensive operations such as searching, data mining, and multimedia processing. In this paper, we propose a new mobile cloud framework called MobiCloud. In addition to providing traditional computation services, MobiCloud also enhances the operation of the ad hoc network itself by treating mobile devices as service nodes. The MobiCloud framework will enhance communication by addressing trust management, secure routing, and risk management issues in the network. A new class of applications can be developed using the enhanced processing power and connectivity provided by MobiCloud. Open research issues for MobiCloud are also discussed to outline future research directions.
Non-dystrophic 129 REJ mice are susceptible to i.p. infection with Listeria monocytogenes despite an ability to recruit inflammatory neutrophils to the peritoneal cavity.

In this study we compared the host response to Listeria monocytogenes in 129 REJ mice with listeria-resistant (C57Bl/6j) and susceptible (Balb/c) mouse strains. In all experiments mice were inoculated by the i.p. route. 129 REJ mice and Balb/c mice were sensitive to listeriosis whilst C57Bl/6j mice were relatively resistant to i.p. infection. Relatively large numbers of viable bacteria could be detected in the spleens of 129 REJ mice as early as 6 h following i.p. inoculation suggesting that dissemination of listeria from the peritoneal cavity is rapid in this mouse strain. This contrasted with Balb/c mice which exhibited an early lag phase during which only low numbers of bacteria could be isolated from the spleens of infected animals. In response to both proteose peptone and live listeria, 129 REJ mice demonstrated a greater capacity to recruit neutrophils to the peritoneal cavity than Balb/c and C57Bl/6j mice. In addition, inflammatory phagocytes from 129 REJ mice were as bactericidal in vitro as phagocytes from the Balb/c and C57Bl/6j strains. However, in vivo, inflammatory neutrophils elicited by proteose peptone prior to i.p. infection with L. monocytogenes were not protective in the three mouse strains tested. Despite the apparent inadequacy of peritoneal neutrophils in controlling early bacterial proliferation, depletion of neutrophils in 129 REJ mice severely exacerbated i.p. infection with L. monocytogenes. The results indicate that neutrophils provide an inefficient but essential means of controlling early outgrowth of listeria in the peritoneal cavity of 129 REJ mice. The excessive inflammatory response seen in 129 REJ mice may facilitate the early dissemination of L. monocytogenes from the peritoneal cavity to peripheral sites.
Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C.

Naphthalenesulfonamides such as N-(6-amino-hexyl)-5-chloro-1-naphthalenesulfonamide (W-7) are potent calmodulin (CaM) antagonists and act upon several protein kinases at higher concentration. When the naphthalene ring was replaced by isoquinoline, the derivatives were no longer CaM antagonists but retained the ability to inhibit protein kinases, and some of the derivatives exhibited selective inhibition toward a certain protein kinase. cAMP-dependent, cGMP-dependent, and Ca2+-phospholipid-dependent (protein kinase C) protein kinases were inhibited significantly by addition of 10(-6) M N-[2-(methylamino)ethyl]-5-isoquinoline-sulfonamide (H-8) and 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine (H-7). H-8 was the most active of the inhibitors in this series and inhibited more markedly cyclic nucleotide dependent protein kinases, than other kinases, while the derivative with the sulfonylpiperazine residue (H-7) was the most potent in inhibiting protein kinase C. Apparent Ki values of H-8 were 0.48 and 1.2 microM for cGMP-dependent and cAMP-dependent protein kinases, respectively, and the Ki value of H-7 for protein kinase C was 6 microM. Both the holoenzyme and the catalytic subunit (or fragment), which is active without an enzyme activator, are susceptible to these compounds with a similar concentration dependency, thereby indicating that the inhibitory effect is attributed to the direct interaction of the compound with the active center of the enzyme but not with the enzyme activator. The inhibitions were freely reversible and of the competitive type with respect to ATP and of the noncompetitive type with respect to the phosphate acceptor. (ABSTRACT TRUNCATED AT 250 WORDS)
Diferencias en el afrontamiento del estrés en estudiantes universitarios hombres y mujeres

En la actualidad son todavia escasos los trabajos que analizan el estres academico universitario desde la perspectiva del genero. En esta investigacion se aborda el estudio de posibles diferencias significativas entre sexos en el afrontamiento de situaciones academicas estresantes. Se plantea un diseno ex post facto prospectivo simple de corte transversal. La muestra estaba compuesta por 2102 estudiantes universitarios de diversos ambitos de conocimiento (Educacion, Ciencias de la Salud, Ciencias Juridico-Sociales y Ciencias Tecnicas), 647 hombres y 1455 mujeres, con edades comprendidas entre los 18 y los 51 anos (M = 21,11; DT = 3,31). Las estrategias de afrontamiento fueron evaluadas a traves de la Escala de Afrontamiento del Estres (A-CEA). Los resultados de este trabajo ponen de manifiesto que los hombres recurren en mayor medida a las estrategias de reevaluacion positiva y planificacion como medidas de afrontamiento de situaciones academicas problematicas, mientras que las mujeres optan fundamentalmente por la busqueda de apoyo. Se analizan posibles causas explicativas de estas diferencias asi como algunas medidas de intervencion tendentes a la reduccion del estres en estudiantes universitarios.
Vicarious and Direct Achievement Patterns in Adulthood

This paper presents a typology of direct and vicarious achievement orientations relevant to adult problems. Direct and vicarious achievement patterns are related to sex role socialization and sex-linked occupational choice. An achievement-sexuality scoring system is described for channeling adults into traditional sex-linked occupations. Recommendations are developed for reevaluating and redesigning adult occupational and interpersonal roles which would take into account vicarious and direct achievement orientations.
Diverse CRISPR-Cas responses and dramatic cellular DNA changes and cell death in pKEF9-conjugated Sulfolobus species

The Sulfolobales host a unique family of crenarchaeal conjugative plasmids some of which undergo complex rearrangements intracellularly. Here we examined the conjugation cycle of pKEF9 in the recipient strain Sulfolobus islandicus REY15A. The plasmid conjugated and replicated rapidly generating high average copy numbers which led to strong growth retardation that was coincident with activation of CRISPR-Cas adaptation. Simultaneously, intracellular DNA was extensively degraded and this also occurred in a conjugated Δcas6 mutant lacking a CRISPR-Cas immune response. Furthermore, the integrated forms of pKEF9 in the donor Sulfolobus solfataricus P1 and recipient host were specifically corrupted by transposable orfB elements, indicative of a dual mechanism for inactivating free and integrated forms of the plasmid. In addition, the CRISPR locus of pKEF9 was progressively deleted when conjugated into the recipient strain. Factors influencing activation of CRISPR-Cas adaptation in the recipient strain are considered, including the first evidence for a possible priming effect in Sulfolobus. The 3-Mbp genome sequence of the donor P1 strain is presented.
Metastatic head and neck malignancy treated using MRI guided interstitial laser phototherapy: An initial case report

Interstitial laser phototherapy (ILP) guided by magnetic resonance imaging (MRI) may become an attractive adjunctive modality for the treatment of deep and surgically inaccessible tumors of the head and neck when accurate methods of laser dosimetry and “real‐time” monitoring techniques with the MRI are introduced. We recently demonstrated in ex vivo and in vivo models, a linear relationship between levels of laser energies, thermal profiles, MR signal intensity changes, and histopathological tissue damage. Results of treatment in a patient with an unresectable large right jugulodigastric metastatic squamous carcinoma using new approach of MRI guided ILP are now reported. The patient complained of significant right‐sided neck pain and headaches secondary to a rapidly growing metastatic lymphadenopathy which recurred after previous surgery, radiation, and chemotherapy. Two treatment sessions were used at an interval of 2 weeks. Each treatment was performed in the MRI suite under heavy sedation. Using a 600‐μm bare fiber of the Nd:YAG laser implanted interstitially under MR guidance, the metastatic node was treated at three sites. T1‐ and T2‐weighted images were performed prior to, immediately after, 24 and 48 hours, and 4, 5, 7, 9, 16, and 25 days post‐treatment. Successful relief of pain and growth arrest of this node was observed after the second treatment and at the 3‐month follow‐up. These results demonstrate that this technique of ILP guided by MRI may be feasible in humans, and will become clinically practical when appropriate methods of dosimetry and instrumentation are developed.
Facilitating teachers in developing online PBL courses

Developing a sound online problem-based learning (PBL) course plan is difficult because teachers need comprehensive PBL and technical knowledge. This paper proposes a model-driven approach to develop a PBL authoring tool that helps teachers create and customize online PBL course plans in a cost-effective and flexible manner. A pilot study was conducted to assess teacher acceptance of the tool. The results reveal that after a short training session, teachers understood the authoring tool and thought the tool was easy to use to develop online PBL course plans.
MOBILIZATION AND PARTICIPATION: SOCIAL-PSYCHOLOGICAL EXPANSIONS OF RESOURCE MOBILIZATION THEORY*

Resource mobilization theorists have nearly abandoned social-psychological analysis of social movements. In this paper a fresh case is made for social psychology. New insights in psychology are combined with resource mobilization theory in an attempt to overcome the weaknesses of traditional social-psychological approaches to social movements. Expectancy-value theory is applied to movement participation and mobilization. It is assumed that the willingness to participate in a social movement is a function of the perceived costs and benefits of participation. Collective and selective incentives are discussed. Expectations about the behavior of others are introduced as an important expansion of expectancy-value theory to make this framework applicable to movement participation. The theory is applied to mobilization campaigns of the labor movement, and empirically tested in a longitudinal study of a campaign during the 1979 collective negotiations in the Netherlands. Outcomes support the theory. Theoretical and practical implications are discussed.
A novel TLR2-triggered signalling crosstalk synergistically intensifies TNF-mediated IL-6 induction

Toll‐like receptors (TLR) recognize pathogens and trigger the production of vigorous pro‐inflammatory cytokines [such as tumour necrosis factor (TNF)] that induce systemic damages associated with sepsis and chronic inflammation. Cooperation between signals of TLR and TNF receptor has been demonstrated through the participation of TNF receptor 1 (TNFR) adaptors in endotoxin tolerance. Here, we identify a TLR2‐mediated synergy, through a MyD88‐independent crosstalk, which enhances subsequent TNF‐mediated nuclear factor‐kappa B activation and interleukin‐6 induction. Membrane‐associated adaptor MAL conduces the link between TNF receptor‐associated factor 6 (TRAF6) and TNFR‐associated death domain, leading to a distinctive K63‐ubiquitinylated TRAF6 recruitment into TNFR complex. In summary, our results reveal a novel route of TLR signal that synergistically amplifies TNF‐mediated responses, indicating an innovative target for inflammation manipulation.
H II galaxies as deep cosmological probes

We re-investigated the use of the Hubble diagram to measure the cosmological constant (Λ) and the mass density of the Universe (ΩM). We find an important focusing effect in Λ for redshifts of about 3. This effect implies that the apparent magnitude of a standard candle at redshifts z=2–3 has almost no dependence on Λ for ΩM>0.2. This means that ΩM can be measured independently of ΩΛ by targeting the redshift range according to an estimate of the value of ΩM. We explore the evidence in support of the suggestion that extreme starburst galaxies, also known as H ii galaxies, can be used as distance estimators over a wide range of redshifts and reaching very high values. We have compiled literature data of H ii galaxies up to z∼3 and found a good correlation between their luminosity and velocity dispersion measured from their strong emission lines, thus confirming the correlation already known to exist for H ii galaxies in the nearby Universe. Several systematic effects, such as age, extinction, kinematics and metallicity, are discussed, as well as the effects of different cosmologies.
Garment modeling with a depth camera

Previous garment modeling techniques mainly focus on designing novel garments to dress up virtual characters. We study the modeling of real garments and develop a system that is intuitive to use even for novice users. Our system includes garment component detectors and design attribute classifiers learned from a manually labeled garment image database. In the modeling time, we scan the garment with a Kinect and build a rough shape by KinectFusion from the raw RGBD sequence. The detectors and classifiers will identify garment components (e.g. collar, sleeve, pockets, belt, and buttons) and their design attributes (e.g. falbala collar or lapel collar, hubble-bubble sleeve or straight sleeve) from the RGB images. Our system also contains a 3D deformable template database for garment components. Once the components and their designs are determined, we choose appropriate templates, stitch them together, and fit them to the initial garment mesh generated by KinectFusion. Experiments on various different garment styles consistently generate high quality results.
One of the Fertility preservation in a family with a novel NR 5 A 1 mutation

The common phenotype of nuclear receptor superfamily 5, group A, member 1 (NR5A1) gene mutations in 46,XY is gonadal dysgenesis without adrenal deficiency. Though the phenotype of gonadal dysgenesis is variable, ranging from complete female to normal male genitalia, an asymptomatic 46,XY male is rare. Preserved fertility has so far been described in only three affected 46,XY males with different mutations, but no functional analysis of these mutations has been performed. Here, we report on male siblings with hypospadias and their asymptomatic father in whom we identified a heterozygous NR5A1 mutation of c.910G>A, p.E304K. Western blotting and subcellular localization revealed no significant difference between the wild type (WT) and E304K. Electrophoretic mobility shift assay experiments showed that E304K abrogated DNA-binding ability. E304K reduced transactivation and had no dominant negative effect. In conclusion, we report on a novel hypomorphic NR5A1 mutation, which may be associated with the phenotype of the family.
What is Practitioner Based Enquiry

Abstract Practitioner Based Enquiry, in which academic credits are awarded for systematic reflection on the process of teaching and learning, is said to have four primary characteristics. Firstly, the educational focus or research problem of Practitioner Based Enquiry derives from and informs the professional concerns of educators. Secondly, such enquiries are conducted as part of a networked and developmental discourse between tutors, practitioners and significant others. Thirdly, practitioners are confirmed in a range of approaches to educational enquiry and research methodology. Fourthly, through the process of enquiry, educators are directed towards the acquisition of intellectual autonomy, improved judgement making, and enhanced technical competence in the classroom. The paper attempts to provide a theoretical schemata for the concept of Practitioner Based Enquiry by answering five important questions: What is Practitioner Based Enquiry? What are the assumptions underlying Practitioner Based Enquiry?
MMSE Design of Time and Color Multiplexing Codes

Illumination multiplexing has proven itself to be a valuable tool in image quality improvement for many computer vision and graphics applications, provided that its limitations on photon noise and saturation are properly tackled. Currently, multiplexing codes are constructed according to the maximum signal-to-noise ratio (SNR), and they are primarily employed for time multiplexing, a technique that requires the number of measurements M to be equal to the number of illumination sources N. In this work, we propose an illumination multiplexing method based on minimum mean square errors (MMSEs) for the more general setting of both time and color multiplexing performed together, with KM ≥ N, where K is the number of color channels. Under the umbrella of the proposed MMSE formulation, the conventional maximum SNR approach can be thought of as a special case of the MMSE design. The formulated MMSE problem is a difficult non-convex problem, but it can be approximated by sequential semi-definite (convex) programming and a 1-D exhaustive search. The proposed formulation and algorithm can be readily specialized to max-SNR and/or time multiplexing designs, thereby giving the optimized codes a much broader scope of application. Computer simulations show that the conventional max-SNR design is suboptimal to the proposed MMSE design, though both see significant quality improvements as M increases. Experiments also demonstrate the effectiveness and superiority of the proposed method in illuminating various objects.
Sheltered Employment and Augmentative Communication: An Oxymoron?

Over the past few years, both augmentative and alternative communication (AAC) consumers and professionals have become increasingly concerned about the problems faced by persons with severe speech and writing impairments in the area of employment. This is no less true for persons with developmental disabilities than for the larger population of AAC consumers. Most of these individuals do not work at all; those that do work spend their days in sheltered workshops rather than in integrated, community employment. This Forum article takes an admittedly “radical” position with regard to the deficiencies of sheltered work settings as contexts for communication. Communication in general, and augmentative communication in particular, is described as being antithetical to the value system, opportunities, and types of relationships available in sheltered workshops. The implications of this oxymoron are discussed, and a brief description of a supported employment model for people with developmental disabilities is d.
Exploring and Promoting Prosocial Vaccination: A Cross-Cultural Experiment on Vaccination of Health Care Personnel

Influenza vaccination for health care personnel (HCP) is recommended particularly because it indirectly protects patients from contracting the disease. Vaccinating can therefore be interpreted as a prosocial act. However, HCP vaccination rates are often far too low to prevent nosocomial infections. Effective interventions are needed to increase HCP's influenza vaccine uptake. Here we devise a novel tool to experimentally test interventions that aim at increasing prosocially motivated vaccine uptake under controlled conditions. We conducted a large-scale and cross-cultural experiment with participants from countries with either a collectivistic (South Korea) or an individualistic (USA) cultural background. Results showed that prosocially motivated vaccination was more likely in South Korea compared to the US, mediated by a greater perception of vaccination as a social act. However, changing the default of vaccination, such that participants had to opt out rather than to opt in, increased vaccine uptake in the US and therefore compensated for the lower level of prosocial vaccination. In sum, the present study provides both a novel method to investigate HCP influenza vaccination behavior and interventions to increase their vaccine uptake.
Arts-Health intersections: a model of practice for consistency in the arts-health sector.

The field of Arts-Health practice and research has grown exponentially in the past 30 years. While researchers are using applied arts as the subject of investigation in research, the evaluation of practice and participant benefits has a limited general focus. In recent years, the field has witnessed a growing concentration on the evaluation of health outcomes, outputs and tangential benefits for participants engaging in Arts-Health practice. The wide range of methodological approaches applied arts practitioners implement make the field difficult to define. This article introduces the term Arts-Health intersections as a model of practice and framework to promote consistency in design, implementation and evaluative processes in applied arts programmes promoting health outcomes. The article challenges the current trend to solely evaluate health outcomes in the field, and promotes a concurrent and multidisciplinary methodological approach that can be adopted to promote evaluation, consistency and best practice in the field of Arts-Health intersections. The article provides a theoretical overview of Arts-Health intersections, and then takes this theoretical platform and details a best model of practice for developing Arts-Health intersections and presents this model as a guide.