Miracle-dz/UniFAR-FTUs huggingface dataset:
[Questionnaire to evaluate the importance of the family in nursing care. Validation of the Spanish version (FINC-NA)].

BACKGROUND The nursing profession is focused on patient care, without forgetting that patients are part of a social group, the family. The aim of this study was the adaptation of the "Families' Importance in Nursing Care-Nurses' Attitudes" (FINC-NA) scale to the Spanish language and its validation. METHODS A descriptive cross-sectional study was carried out, using the bidirectional translation method for linguistic-cultural adaptation. It was applied to the nursing staff in the Paediatric Department of a University Hospital in Madrid. To evaluate the psychometric properties of the Spanish version, reliability, internal consistence and construct validity were calculated. RESULTS The sample consisted of 274 professionals. Cronbach´s Alpha coefficient for the total scale was 0.864, oscillating between 0.888 and 0.769 in the subscales. The principal components factor analysis identified 4 factors, which explained 54.22% of total variance. CONCLUSIONS The new instrument makes it possible to determine the importance nurses give to participation by family members and their attitude to involving the latter in patient care, and the possibility of involving them in planning. It has been adapted to the Spanish population with good psychometrics results and enough evidence for its use in this context.
Clinical simulation in maternity (CSiM): interprofessional learning through simulation team training

Background Focusing on interprofessional relations in team performance to improve patient safety is an emerging priority in obstetrics. A review of the literature found little information on roles and teamwork in obstetric emergency training. Qualitative research was undertaken through a Clinical Simulation in Maternity programme which gives interprofessional rural clinicians the opportunity to learn collaboratively through simulated obstetric emergencies. This research aimed to determine how interprofessional simulation team training improved maternity emergency care and team performance. Method This research used thematic inductive analysis using data from in-depth interviews. In total 17 participants and four facilitators who took part in the Clinical Simulation in Maternity workshops were invited to participate in an interview 1–2 weeks postworkshop and then again 3–6 months later. Data were deidentified then coded manually and with the assistance of computer program NVivo 7 (QSR International). Findings Of the major themes identified, Collaboration in Teambuilding was separated into four subthemes (Personal Role Awareness, Interpositional Knowledge, Mutuality and Leadership). Conclusion This research highlights the significance of interprofessional training, particularly through simulation learning in a team where rural clinicians are able to learn more about each other and gain role clarity, leadership skills and mutuality in a safe environment.
Application development for recognizing type of infant's cry sound

Crying infant is a sign of baby who has a problem. But, some people are not able to recognize the meaning of infant's cry. Several researches to recognize infant's cry sound had been done by some researchers, but there is still no research that develop an application which able to recognize type of infant's cry sound based on web. In this research, an application is developed to help users identify the sound of crying infant based on Dunstan Baby Language. The method applied in this application are Mel-Frequency Cepstral Coefficient (MFCC) feature extraction for infant's cry sound, normalization of feature extraction result, and K-nearest neighbor classification. From the various tests performed, it can be concluded that highest average accuracy of 75.95 percent can be obtained by using parameters consist of 0.08 seconds wintime in MFCC feature extraction, 85 percent of training data and 15 percent of test data from any type of infant's cry sound, feature extraction normalization by Standard Deviation Normalization, and K-nearest Neighbor with k equal to 1 classification. While testing application by using all data, average accuracy of 96.57 percent can be obtained by using parameters consist of 0.08 seconds wintime in MFCC feature extraction, 85 percent of training data from any type of infant's cry sound, feature extraction normalization by Standard Deviation Normalization, and K-nearest Neighbor k equal to 1 classification. From that test, it can be concluded that the application has been running well when classifying all types of infant's cry sound data.
Coronally advanced flap for the treatment of buccal gingival recessions with and without enamel matrix derivative. A split-mouth study.

BACKGROUND The coronally advanced flap (CAF) is a predictable method for achieving root coverage in buccal gingival recessions. The use of enamel matrix derivative (EMD) has already been tested in treating intrabony defects. No clinical comparative study has been published evaluating the CAF in combination with EMD in treating buccal gingival recessions. METHODS This split-mouth study was performed to assess the efficacy of EMD to improve the results of a root coverage procedure. Fourteen pairs of Miller Class I and II bilateral comparable defects were selected in 12 patients. In each patient, one site was randomly assigned to the test group and the contralateral site to the control group. The treatment consisted of a CAF procedure with (test) or without (control) EMD. Gingival recession (REC), clinical attachment level (CAL), probing depth (PD), and extension of keratinized tissue (KT) were recorded at baseline and 6 months postsurgery. RESULTS The average initial REC was 3.71 mm (SD +/- 1.68) for the test group, and 3.50 mm (SD +/- 1.56) for the control group. The 2 groups were statistically homogeneous. The mean root coverage was 3.36 mm (SD +/- 1.55), corresponding to a value of 91.2% for the test group, and 2.71 mm (SD +/- 1.20), equal to 80.9% for the control group. The differences between the 2 groups were not statistically significant. The mean CAL gain was 3.57 mm (SD +/- 1.55) for the test group and 2.79 mm (SD +/- 1.19) for the control group. No changes of PD and KT were found. CONCLUSIONS This study suggests that EMD does not seem to significantly improve the clinical outcomes of gingival recession treated by means of CAF, even though the test group showed slightly better results in terms of root coverage and CAL. Further studies with a larger number of teeth and higher statistical power are needed to support this conclusion.
Dynamic Evolution of Hashtags on Twitter: A Case Study from Career Opportunities Groups

Online Social Networks (OSNs) are defined as a network of relationships where human entities represent the nodes and the edges between these nodes represent the relationships leading to online communities. Due to the rapid growth of social media networks and the consequent growth of communities on such networks, it was of great interest for researchers to study the evolution of such communities to know how they retain their members, attract new ones and grow over time. This paper focuses on the factors causing people to participate in certain communities on Twitter, which in turn affects the evolution of these communities. In order to study this evolution, a dataset of some Twitter hashtags related to career opportunities was collected for a period of two months between February and March 2016. The collected dataset allowed us to study the reciprocal effect of the users’ topological features and their activity levels. In this paper, three new measures are introduced (two influence measures and one topological measure). Those measures, in addition to the measures available in the literature, are used to spot the measures that can be used for influencing a user to attract other users to a certain hashtag. Focus is on the centrality and the activity level of participants and their effect on the activity level or the membership of other users on same communities.
Bacterial Contamination of Needle Points after Intravitreal Injection

Purpose Evaluation of the magnitude and pattern of bacterial contamination of needle points with conjunctival bacteria during the intravitreal injection. Analysis of the efficacy of preinjection prophylaxis. Methods A total of 550 intravitreal injections were done in 414 patients (n=425 eyes). A total of 289 patients were injected once, while 125 patients received several injections. Before the intravitreal injection in the operation room, the following standard preoperative preparation of the eye–10% povidone iodine scrub on the eyelids, eyelashes and forehead and irrigation of the conjunctival sac with 1% povidone iodine–was carried out. Immediately after the injection, the needle points were rinsed three times in thioglycolate broth, which was cultured at 35°C for 5 days afterwards. As a negative control, 200 sterile unused needle points were treated the same way. Results Only 2 out of 550 (0.36%) needle points were contaminated after intravitreal injection. In sensitivity testing, the isolated Staphylococcus epidermidis and Corynebacterium sp did not show multidrug resistance. All 200 unused needle points proved to be sterile after 5 days of cultivation. Conclusions Contamination of needle points is minimal after iodine irrigation prophylaxis before intravitreal injection. Therefore, we recommend this prophylaxis technique before intravitreal injections. The low incidence of contaminated needle points, however, shows that there still is a risk of bacteria entering into the eye during injection.
[Surgical strategy for severe cervical spine dislocations].

OBJECTIVE To evaluate the rate of open reduction and surgical strategy of severe cervical dislocation. METHODS From March 2001 to March 2006, the data of 92 cases of cervical dislocation over 1/2 were retrospectively studied. Garden Well traction with 1 - 3 kg weight were performed before operation. The patients were performed with diskectomy and reduction with anterior approach initially, for those that can not be reduced, corpectomy were performed and reduction procedures were repeated. The posterior reduction and fixation were followed when reduction can not be reached with anterior approach only. The succeed rate of reduction, rate of tracheotomy were recorded and fusion rate, Frankel score and visual analog scale (VAS) were evaluated. RESULTS Reduction succeed in 38 cases after diskectomy, 44 after corpectomy and 7 after combined anterior-posterior-anterior procedure. Three cases got incompleteness reduction. Tracheotomy was done in 29 cases. The Frankel score increased 0.5 degree and VAS was 2 averagely at the last follow-up. CONCLUSIONS The succeed rate of anterior open reduction was 89.2%, and only 10.8% patients needs an additional combined posterior and anterior approach. For patients with completed spinal cord injury with dislocation above C(4), or with dislocation below C(5) but the edema on MRI T2 image are above C(4) level need tracheotomy. The operation be done until respiratory function stable. For patients with completed spinal cord injury with dislocation below C(4) and uncompleted spinal cord injury with dislocation above C(4), the rate of tracheotomy is relatively lower and early operation is recommended.
Use of cyclodextrins as modifiers of fluorescence in the detection of mycotoxins

Cyclodextrins, cyclic oligosaccharides composed of amylose subunits, are known to interact with mycotoxins. The interactions may be useful to analytical chemists by altering the properties of the mycotoxin of interest, namely the chromatographic properties, electrophoretic properties, fluorescence, or absorption of these fungal metabolites. Practical applications of these effects have been the incorporation of cyclodextrins into high-performance liquid chromatography and capillary electrophoresis methods for mycotoxin detection. Specific mycotoxins include those with a native fluorescence such as the aflatoxins, ochratoxin A (OTA) and zearalenone (ZEN) as well as those that can be rendered fluorescent through derivatization, such as T-2 toxin. The literature describing the applications of cyclodextrins in mycotoxin analysis is reviewed and an attempt to extend the use of cyclodextrins to the detection of labelled T-2 toxin is presented. Twenty cyclodextrins were evaluated for their ability to enhance the fluorescence emission of T-2 toxin derivatized with pyrene-1-carbonyl cyanide (T2-Pyr). This evaluation revealed that heptakis (2,6-di-O-methyl)-β-cyclodextrin (DIMEB), in particular, enhanced T2-Pyr fluorescence. DIMEB was used as a buffer modifier in a capillary electrophoresis-laser-induced fluorescence (CE-LIF) method for detecting T-2 in maize. Because of the effects that certain cyclodextrins have, especially under aqueous conditions, they may make useful additives for a variety of mycotoxin analytical methods.
Prostaglandin D2, its metabolite 15‐d‐PGJ2, and peroxisome proliferator activated receptor‐γ agonists induce apoptosis in transformed, but not normal, human T lineage cells

Prostaglandin D2 (PGD2) is abundantly produced by mast cells, platelets, and alveolar macrophages and has been proposed as a key immunoregulatory lipid mediator. 15‐Deoxy‐Δ12,14‐PGJ2 (15‐d‐PGJ2), a key PGD2 metabolite, is under intense study as a potential anti‐inflammatory mediator. Little is known about PGD2 or the role of 15‐d‐PGJ2, if any, in regulating the activities of human T lineage cells. In this report we demonstrate that both PGD2 and 15‐d‐PGJ2 have potent antiproliferative effects, and in fact kill human T lymphocyte lines derived from malignant cells by an apoptotic mechanism. Interestingly, normal human T cells were not similarly affected. Although the T lymphocyte lines express mRNA for the PGD2 receptor (DP‐R), a potent DP receptor agonist, BW245C, did not inhibit the proliferation or viability of the cells, suggesting an alternative mechanism of action. PGD2 and 15‐d‐PGJ2 can bind to the peroxisome proliferator activated receptor‐γ (PPAR‐γ) which is implicated in lipid metabolism and apoptosis. Exposure to synthetic PPAR‐γ ligands (e.g. ciglitazone, troglitazone) mimicked the inhibitory responses of PGD2 and 15‐d‐PGJ2, and induced apoptosis in the transformed T cells consistent with a PPAR‐γ‐dependent mechanism. These observations suggest that PPAR‐γ ligands (which may include PGD2) provide strong apoptotic signals to transformed, but not normal T lymphocytes. Thus, the efficacy of utilizing PPAR‐γ and its ligands as therapeutics for human T cell cancers needs to be further evaluated.
Olmesartan/amlodipine: blood pressure lowering and beyond in special populations

Clinical studies and population-based analyses show that in patients with hypertension, the majority cannot control their blood pressure (BP) by treatment with a single antihypertensive agent. Combining agents from different antihypertensive classes with complementary modes of action significantly increases efficacy and is a treatment strategy recommended by European treatment guidelines, particularly in patients at high cardiovascular risk. The combinations of antihypertensive agents recommended by the European guidelines include an angiotensin receptor blocker (ARB) with a calcium channel blocker (CCB). The single-pill combination formulation of the ARB olmesartan medoxomil plus the CCB amlodipine is an effective and well-tolerated treatment that provides greater blood pressure lowering and control than the component monotherapies and favours compliance by not increasing pill burden. Importantly, the efficacy and tolerability of olmesartan plus amlodipine is not affected by age, gender, hypertension severity, diabetes status, race or body mass index. Additional blood pressure lowering effects are observed with stepwise uptitration of olmesartan plus amlodipine with or without hydrochlorothiazide, with more patients achieving blood pressure goals. In addition, olmesartan plus amlodipine has demonstrated effects beyond BP lowering by showing beneficial effects on markers of inflammation, endothelial dysfunction and oxidative stress, as well as metabolic improvements and a reduction in new-onset diabetes incidence in hypertensive patients with metabolic syndrome.
Text/Non-text Ink Stroke Classification in Japanese Handwriting Based on Markov Random Fields

In this paper, we present an approach for separating text and non-text ink strokes in online handwritten Japanese documents based on Markov random fields (MRFs), which effectively utilize the spatial relationship between strokes. Support vector machine (SVM) classifiers are trained for individual stroke and stroke pair classification, and on converting the SVM outputs to probabilities, the likelihood clique potentials of MRF are derived. In experiments on the TUAT Kon-date database, the proposed MRF approach yield superior performance compared to individual stroke classification and sequence classification based on hidden Markov models (HMMs).
Caractérisation et valorisation de sédiments fluviaux pollués et traités dans les matériaux routiers

Chaque annee, pres de 50 millions de m3 de sediments sont extraits des ports et des cours d'eau francais. Dans le Nord-Pas de Calais, region ayant connu un important essor industriel au XXe siecle, une proportion importante des boues draguees presente des teneurs en metaux lourds et/ou en matiere organique elevees. Les filieres d'elimination classiques telles que l'epandage ou le stockage n'etant pas ou peu adaptees aux materiaux fortement pollues, des procedes de traitement ont ete mis au point. Une fois traites, il est possible d'envisager la valorisation des sediments dans les materiaux du Genie Civil. L'objet de ce travail de these concerne la valorisation de sediments fluviaux, pollues et traites par le procede Novosol®, developpe par la societe Solvay, dans le domaine de la construction routiere. Une premiere etape de caracterisation physico-chimique et geotechnique des sediments traites Novosol® (STN) a etabli la faisabilite de leur valorisation en couche de forme. Il a egalement ete mis en evidence qu'ils presentaient une reactivite hydrique et pouzzolanique. L'influence de la nature du liant sur le traitement des STN a ensuite ete abordee. D'apres les resultats des essais mis en œuvre (aptitude au traitement, gonflement, portance, resistance en compression et en traction Bresilienne), 2 des 5 liants testes se distinguent particulierement et presentent un niveau de performance de classe 3 selon le Guide du Traitement des Sols. Il s'agit du Roc Sol et la chaux vive. Enfin, une etude complementaire a montre qu'il etait egalement possible de valoriser les STN en remblais autocompactant. Cependant, cette voie necessiterait d'etre approfondie.
MRCP vs ERCP in the evaluation of biliary pathologies: Review of current literature

OBJECTIVE: Recently developed magnetic resonance (MR) techniques permit fast and correct imaging of the entire biliary tree with a high spatial resolution. The aim of this study was to compare the diagnostic potential of one of these new MR sequences in magnetic resonance cholangiopancreatography (MRCP) procedure and endoscopic retrograde cholangiopancreatography (ERCP) with review of current literatures.
Free flow‐isoelectric focusing of human cellular lysates as sample preparation for protein analysis

A whole cell lysate of human cells was separated into 80 fractions according to the pI of proteins using free flow isoelectric focusing with carrier ampholytes. The resolution of the process was highly reproducible, with an overlap of fractions of less than 30%. A protein of a faint silver stained spot in two‐dimensional gel electrophoresis (2‐DE) could be enriched, yielding a Coomassie blue stained spot which could be further characterized by proteinchemical methods. The enrichment of less abundant proteins from a complex crude cell extract was found to be a suitable tool for sample preparation and enrichment before applying proteins to 2‐DE and reversed‐phase high performance liquid chromatography.
Sports and the solitary kidney: how to counsel parents.

OBJECTIVE To determine how to counsel parents of young children with a solitary kidney in a manner compliant with the recommendations of the American Academy of Pediatrics (AAP). METHODS As per the AAP recommendations, the relevant information required to provide a Qualified Yes to involvement in contact/collision sports was obtained through a PubMed search and local inquiries. Questions specifically addressed were: . Available published information on risks of participation . Availability of effective protective equipment that is acceptable to the athlete . Whether the sport can be modified to allow safer participation. RESULTS Pediatric renal trauma can result from sporting injuries, however more renal injuries are caused by motor vehicle accidents. Those sports associated with a higher risk of significant renal injury carry a five-fold higher risk of head injury. Tolerable protective equipment is available, but whether it decreases risk of renal trauma is unknown. Participation in high-risk sports can be modified to allow safer participation. CONCLUSIONS Parents need to be counseled on the consequences of an injury to the solitary kidney, and potential ways to decrease such risks without being unnecessarily restrictive with respect to sports participation. Specific information to convey to parents in a concise manner is provided.
A Comparison Between Phorbol 12 Myristate 13 Acetate and Phorbol 12, 13 Dibutyrate in Human Melanocyte Culture.

INTRODUCTION Melanocyte culture is an integral part of the studies of skin biology and cosmetic applications. After the introduction of selective medium for the culture of human melanocyte using Phorbol 12-myristate13-acetate (PMA) in 1982, a lot of methods of culturing were tried but till date PMA is a preferred mitogen because of its cost effectiveness compared to growth factors. We have tried to preliminarily evaluate the efficacy of another phorbol ester, Phorbol 12, 13-dibutyrate (PDBu) in melanocyte culture because of its less hydrophobic nature compared to PMA. This property minimizes the trace amount of mitogen in cell culture after washing off and hence does not interfere in other biological assays. AIM To evaluate the differences in the melanocyte survival rate, morphology and mitotic index when grown in media supplemented with PMA and PDBu. MATERIALS AND METHODS Foreskins were collected from children undergoing circumcision. Epidermal cells were isolated from foreskin and cultured using PMA and PDBu. Melanocytes in culture were monitored for the better establishment and documented. In proliferative assay, melanocytes were treated with PMA and PDBu for 24, 48 and 72 hours and proliferation was measured using 3-(4,5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay method. RESULTS When cultured, melanocytes acquired proliferative status and bipolar morphology quicker in PDBu medium than in PMA medium. Keratinocytes survived as contamination in PMA medium whereas PDBu medium had minimal keratinocytes. MTT assay showed that PDBu has higher proliferative induction capacity than PMA. In even lower concentration of PDBu in medium, melanocytes survived till 72 hours without significant cell loss in compared to PMA medium. CONCLUSION PDBu can be a valuable replacement for PMA in human melanocyte culture. Higher proliferation induction, unfavourable to keratinocyte survival and less hydrophobicity make PDBu a promising alternative for quicker establishment of pure human melanocyte cultures especially in cosmetic in vitro experimental dermatology.