Miracle-dz/UniFAR-FTUs huggingface dataset:
John Bolton and the nature of discrete radio sources

John Bolton is regarded by many to be the pre-eminent Australian astronomer of his generation. In the late 1940s he and his colleagues discovered the first discrete sources of radio emission. Born in Sheffield in 1922 and educated at Cambridge University, in 1946 Bolton joined the Radiophysics Laboratory in Sydney, part of Australia’s Council for Scientific and Industrial Research. Radio astronomy was then in its infancy. Radio waves from space had been discovered by the American physicist Karl Jansky in 1932, followed by Grote Reber who mapped the emission strength across the sky, but very little was known about the origin or properties of the emission. This thesis will examine how the next major step forward was made by Bolton and colleagues Gordon Stanley and Bruce Slee. In June 1947, observing at the Dover Heights field station, they were able to show that strong radio emission from the Cygnus constellation came from a compact point-like source. By the end of 1947 the group had discovered a further five of these discrete radio sources, or ‘radio stars’ as they were known, revealing a new class of previously-unknown astronomical objects. By early 1949 the Dover Heights group had measured celestial positions for the sources accurately enough to identify three of them with known optical objects. One coincided with an unusual object in the local Galaxy and two coincided with peculiar extragalactic objects. As I will show, the optical identifications built a bridge between traditional astronomy and the fledgling radio astronomy. The identifications also marked the birth of extragalactic radio astronomy, which was to have a major impact on the development of astronomy in the second half of the twentieth century. In the early 1950s, with improved instrumentation, the Dover Heights group carried out a sky survey that revealed over 100 radio sources, consolidating its position as the world’s leading group for ‘cosmic’ radio astronomy. To conclude, I will briefly survey Bolton’s career after the closure of Dover Heights in 1954. Bolton had the unusual distinction of being the inaugural director of two major observatories, first at the California Institute of Technology (1955–60) and then at the Parkes Observatory (1961–81) in central NSW. No astronomer did more over his career to establish radio astronomy as a mature and powerful branch of astronomy.
C2-continuous Path Planning by Combining Bernstein-Bézier Curves

This work proposes fifth order Bernstein-Bézier (BB) curve segments to be used in path planning approaches. The combined path consists of BB spline sections with continuous second derivative in connections which means that the path curvature is continuous and feasible for wheeled robot to drive on. To further minimize the travelling time on this path a velocity profile is optimized by considering acceleration and velocity constraints.
The Physical Activity Support Needs and Strategies Scale: Its Development and Use.

People with intellectual disability (ID) engage in insufficient physical activity which negatively affects their health. In accordance with the present conception of ID and the supports paradigm, the current study aimed to develop and psychometrically assess an instrument examining the support needs and strategies regarding physical activity by using individuals with ID (n = 529), service providers (n = 522), and family members (n = 462) as information sources. The analysis revealed adequate reliability for the proposed instrument, with α values between . 70 and . 80, and adequate construct validity for the versions of the scale for the 3 information sources, particularly for service providers. The assessment information can be included in Individualized Support Plans and could be used to design and implement the strategies for facilitating a person's physical activity in their community.
Multi triangle based automatic face recognition system by using 3D geometric face feature

Automatic human face recognition is required in numerous applications. In this paper, a new approach for automatic face recognition system is developed based on 3D geometric face features. The objectives of this system are generating the real time automatic personal identification system, improvement of fast and accurate face recognition. The system developed the algorithm for computing the accurate 3D measurement of face features. It is based on the perspective projection of a triangle constructed from three nodal points extracted from two eyes and lips corners. The set of non-linear equation is established the nodal points of a triangle built by any three points in a 2D scene and their corresponding projected image points. Some mathematical concepts are used to calculate the distances and angles between feature points. The proposed system is not only recognizing the person but also extracting the personal information of a person from database.
, Sebastian Resonance : Comparison With Myocardial Perfusion Scintigraphy Ischemic Burden by 3-Dimensional Myocardial Perfusion Cardiovascular Magnetic

Background: The extent and severity of ischemia on myocardial perfusion scintigraphy (MPS) is commonly used to risk-stratify patients with coronary artery disease. Estimation of ischemic burden by cardiovascular magnetic resonance (CMR) with conventional 2-dimensional myocardial perfusion methods is limited by incomplete cardiac coverage. More recently developed 3-dimensional (3D) myocardial perfusion CMR, however, provides whole-heart coverage. The aim of this study was to compare ischemic burden on 3D myocardial perfusion CMR with 99mTc-tetrofosmin MPS. Methods and Results—Forty-five patients who had undergone clinically indicated MPS underwent rest and adenosine stress 3D myocardial perfusion and late gadolinium enhancement CMR. Summed stress and rest scores were calculated for MPS and CMR using a 17-segment model and expressed as a percentage of the maximal possible score. Ischemic burden was defined as the difference between stress and rest scores. 3D myocardial perfusion CMR and MPS agreed in 38 of the 45 patients for the detection of any inducible ischemia. The mean ischemic burden for MPS and CMR was similar (7.5±8.9% versus 6.8±9.5%, respectively, P=0.82) with a strong correlation between techniques (rs=0.70, P<0.001). In a subset of 33 patients who underwent clinically indicated invasive coronary angiography, sensitivities and specificities of the 2 techniques to detect angiographic coronary artery disease were similar (McNemar P=0.45). Conclusions—3D myocardial perfusion CMR is an alternative to MPS for detecting the presence and rating the severity of ischemia. DOI: 10.1161/CIRCIMAGING.113. 001620 Posted at the Zurich Open Repository and Archive, University of Zurich ZORA URL: http://doi.org/10.5167/uzh-98659 Published Version Originally published at: Jogiya, R; Morton, G; De Silva, K; Reyes, E; Hachamovitch, R; Kozerke, S; Nagel, E; Underwood, S R; Plein, S (2014). Ischemic Burden by 3-Dimensional Myocardial Perfusion Cardiovascular Magnetic Resonance: Comparison With Myocardial Perfusion Scintigraphy. Circulation. Cardiovascular Imaging, 7(4):647-654. DOI: 10.1161/CIRCIMAGING.113. 001620 Kozerke, Eike Nagel, S. Richard Underwood and Sven Plein Roy Jogiya, Geraint Morton, Kalpa De Silva, Eliana Reyes, Rory Hachamovitch, Sebastian Resonance: Comparison With Myocardial Perfusion Scintigraphy Ischemic Burden by 3-Dimensional Myocardial Perfusion Cardiovascular Magnetic Print ISSN: 1941-9651. Online ISSN: 1942-0080 Copyright © 2014 American Heart Association, Inc. All rights reserved. Dallas, TX 75231 is published by the American Heart Association, 7272 Greenville Avenue, Circulation: Cardiovascular Imaging doi: 10.1161/CIRCIMAGING.113. 00162
Experiments Toward a Mutual Adaptive Speech Interface That Adopts the Cognitive Features Humans Use for Communication and Induces and Exploits Users' Adaptations

Interactive agents such as pet robots or adaptive speech interface systems that require forming a mutual adaptation process with users should have two competences. One of these is recognizing reward information from users' expressed paralanguage information, and the other is informing the learning system about the users by means of that reward information. The purpose of this study was to clarify the specific contents of reward information and the actual mechanism of a learning system by observing how 2 persons could create a smooth speech communication, such as that between owners and their pets. A communication experiment was conducted to observe how human participants create smooth communication through acquiring meaning from utterances in languages they did not understand. Then, based on experimental results, a meaning-acquisition model that considers the following 2 assumptions was constructed: (a) To achieve a mutual adaptive relationship with users, the model needs to induce users' adaptation and to exploit this induced adaptation to recognize the meanings of a user's speech sounds; and (b) to recognize users' utterances through trial-and-error interaction regardless of the language used, the model should focus on prosodic information in speech sounds, rather than on the phoneme information on which most past interface studies have focused. The results confirmed that the proposed model could recognize the meanings of users' verbal commands by using participants' adaptations to the model for its meaning-acquisition process. However, this phenomenon was observed only when an experimenter gave the participants appropriate instructions equivalent to catchphrases that helped users learn how to use and interact intuitively with the model. Thus, this suggested the need for a subsequent study to discover how to induce the participants' adaptations or natural behaviors without giving these kinds of instructions.
Down‐Regulation of c‐neu Receptors by Nerve Growth Factor in PC12 Cells

Abstract: A small number of p185c‐neu receptors have been found on PC12 cells. These receptors show some basal phosphorylation in quiescent cells. When the cells are treated with nerve growth factor (NGF) for a short time, some increase in phosphorylation is seen, mainly on serine and threonine residues, and this is accompanied by a slight shift in the apparent molecular weight. Epidermal growth factor (EGF) also increases the phosphorylation of p185c‐neu, in this case on tyrosine residues. Neither heregulin‐β1 nor gp30 stimulates the tyrosine phosphorylation of p185c‐neu, and neither has a proliferative effect on the cells. Treatment of the cells with NGF for 5 days produces a 70–80% reduction in the number of p185c‐neu receptors. This down‐regulation does not occur when PC12nnr5 cells, which lack the high‐affinity NGF receptor, p140trk, are treated with NGF.The level of p185c‐neu mRNA is not altered by NGF treatment, suggesting that the down‐regulation is due to either a translational or a posttranslational alteration.
Psychiatric risk factors for traumatic brain injury

Objective: To examine the risk of sustaining a traumatic brain injury (TBI) associated with prior psychiatric conditions beyond that of fixed demographic variables. Design: Retrospective cohort study of non-referred community-dwelling male US veterans. Methods: Two-hundred and seventy-one individuals who sustained a TBI with altered consciousness were compared with 630 controls without a history of head injury, selected from a larger sample of 3766. Results: Hierarchical logistic regression analyses were used to model odds ratios and 95% confidence intervals for the unique association between pre-existing psychiatric disorders and the likelihood of incurring a TBI while adjusting for demographic characteristics and other known predictor variables. Mood (odds ratio 2.48, 95% confidence interval 1.23–5.01), anxiety (OR 1.64, 95% CI 1.01–2.68) and conduct disorders (OR 1.66, 95% CI 1.16–2.38) increased the risk of head injury. Conclusions: The pre-existence of psychiatric illness, particularly depression, anxiety and conduct disorder, increased the future risk of incurring a TBI. The implementation of early identification and treatment of psychiatric conditions may potentially lower risk and reduce yearly incidence rates of TBI.
Performance comparison of different multiple input multiple output system

MIMO systems are widely used in several wireless communication systems because it has the ability to provide high reliability and increased capacity without the use of increased transmit power. MIMO systems use space time codes to achieve diversity at both sections of transmitter and receiver. Here the design of MIMO and MISO systems are performed with multicarrier delay diversity modulation techniques which use both cyclic delay diversity and orthogonal frequency division multiplexing (OFDM). Due to the bandwidth efficiency and the ability to reduce multipath effect OFDM is used in several wireless standards. Design and simulation is done in MATLAB using an AWGN channel for BPSK and QPSK modulation schemes to obtain a performance comparison of MISO and MIMO systems in terms of bit error rate.
ANAK SEBAGAI QURRATU A’YUN DALAM PERSPEKTIF AL-QUR’AN

Keluarga merupakan pilar dalam bermasyarakat. Kebaikan bangsa terukur dari keluarga yang ada pada negara tersebut, keluarga kuat maka sebuah negara akan kuat, sebaliknya jika dalam sebuah negara keluarga-keluarga di dalamnya lemah maka akan lemah pula negara tersebut. Penguatan unsur keluarga harus dilakukan seluruh anggota keluar, baik bapak, ibu dan anak. Dalam tema tulisan ini penguatan keluar yang akan ditekankan adalah anak. Anak merupakan salah satu sumber kebahagian dalam keluarga, sehingga sekuat tenaga setiap keluarga mengharapakan anaknya dapat menjadi Qurratu ‘Ayun bagi mereka. Maka dalam penelitian ini akan dibahas tentang hakikat dari Qurratu ‘Ayun berdasarkan ayat-ayat Al-Quran, serta penjelasan para ulama mengenai hakikat dari Qurratu ‘Ayun.
Prevention of post-operative intra-nasal adhesions

Abstract A new material, the wax paper enveloping the Fucidin® gauze which is routinely used to pack the nose post-operatively, was utilized in 120 cases considered as ‘high-risk’ for the formation of post-operative nasal adhesions. This proved to be an inexpensive, simple and effective method when the prevention of the formation of nasal adhesions was the primary goal.
Association of MRI metrics and cognitive impairment in radiologically isolated syndromes

Objective: To evaluate cognitive changes in a cohort of radiologically isolated syndromes (RIS) suggestive of multiple sclerosis (MS) and to assess their relationship with quantitative magnetic resonance (MR) measures such as white matter (WM), lesion loads, and cerebral atrophy. Methods: We assessed the cognitive performance in a group of 29 subjects with RIS recruited from 5 Italian MS centers and in a group of 26 patients with relapsing-remitting MS (RRMS). A subgroup of 19 subjects with RIS, 26 patients with RRMS, and 21 healthy control (HC) subjects also underwent quantitative MR assessments, which included WM T1 and T2 lesion volumes and global and cortical brain volumes. Results: Cognitive impairment of the same profile as that of RRMS was found in 27.6% of our subjects with RIS. On MR scans, we found comparable levels of lesion loads and brain atrophy in subjects with RIS and well-established RRMS. In subjects with RIS, high T1 lesion volume (ρ = 0.526, p = 0.025) and low cortical volume (ρ = −0.481, p = 0.043) were associated with worse cognitive performance. Conclusions: These findings emphasize the importance of including accurate neuropsychological testing and quantitative MR metrics in subjects with RIS suggestive of MS. They can provide a better characterization of these asymptomatic subjects, potentially useful for diagnostic and therapeutic decisions.
MicroRNA-21 inhibits platelet-derived growth factor-induced human aortic vascular smooth muscle cell proliferation and migration through targeting activator protein-1.

OBJECTIVES This study is to investigate whether microRNA (miR)-21 inhibits platelet-derived growth factor-induced human aortic vascular smooth muscle cell (VSMC) proliferation and migration through targeting activator protein-1 (AP-1). METHODS VSMCs were transfected with the miR-21 or miR-21 inhibitor. Cell proliferation was determined using methyl thiazolyl tetrazolium assay. Cell migration was detected by transwell assay. Luciferase reporter assay was used to study the interaction between miR-21 and AP-1. The levels of mRNA were determined using quantitative real-time polymerase chain reaction, while protein expression was measured using Western blotting assay. RESULTS Low expression of miR-21 significantly inhibited VSMC proliferation, invasion and migration. The mRNA levels and protein expression of α-SMA and AP-1 were down-regulated by low expression of miR-21. In addition, luciferase reporter assay demonstrated that AP-1 might be a direct target gene of miR-21 in VSMC initiation and development. Moreover, up-regulation of AP-1 was critical for miR-21-mediated inhibitory effects on platelet-derived growth factor-induced cell proliferation and migration in human VSMCs. CONCLUSIONS In summary, miR-21 is a key molecule in regulating human VSMC proliferation and migration by targeting AP-1, suggesting that specific modulation of miR-21 in human VSMCs may become an attractive approach for the treatment of proliferative vascular diseases.
Immunofluorescent studies of RD-114 virus replication in cell culture.

Summary Newly formed gs-1 antigen of RD-114 virus was detected by the indirect fluorescent antibody (IFA) procedure in the cytoplasm of the D-17 dog cell line at 24 h post-infection in approx. 30% of the cells. Virus-induced membrane antigen was present in approx. 50% of the cells by 48 h, at which time new infectious virus was being produced. Polykaryons were observed in infected cells. Their formation paralleled production of virus, as determined by the IFA membrane staining technique.
Pure Hemozoin Is Inflammatory In Vivo and Activates the NALP3 Inflammasome via Release of Uric Acid1

The role of proinflammatory cytokine production in the pathogenesis of malaria is well established, but the identification of the parasite products that initiate inflammation is not complete. Hemozoin is a crystalline metabolite of hemoglobin digestion that is released during malaria infection. In the present study, we characterized the immunostimulatory activity of pure synthetic hemozoin (sHz) in vitro and in vivo. Stimulation of naive murine macrophages with sHz results in the MyD88-independent activation of NF-κB and ERK, as well as the release of the chemokine MCP-1; these responses are augmented by IFN-γ. In macrophages prestimulated with IFN-γ, sHz also results in a MyD88-dependent release of TNF-α. Endothelial cells, which encounter hemozoin after schizont rupture, respond to sHz by releasing IL-6 and the chemokines MCP-1 and IL-8. In vivo, the introduction of sHz into the peritoneal cavity produces an inflammatory response characterized by neutrophil recruitment and the production of MCP-1, KC, IL-6, IL-1α, and IL-1β. MCP-1 and KC are produced independently of MyD88, TLR2/4 and TLR9, and components of the inflammasome; however, neutrophil recruitment, the localized production of IL-1β, and the increase in circulating IL-6 require MyD88 signaling, the IL-1R pathway, and the inflammasome components ICE (IL-1β-converting enzyme), ASC (apoptosis-associated, speck-like protein containing CARD), and NALP3. Of note, inflammasome activation by sHz is reduced by allopurinol, which is an inhibitor of uric acid synthesis. These data suggest that uric acid is released during malaria infection and may serve to augment the initial host response to hemozoin via activation of the NALP3 inflammasome.
Constraint Adaptation in Web Service Composition

Service constraints are usage restrictions on service features that are imposed by service providers. Such constraints need to be verified prior to the execution of a service in order to ensure correct service execution. In the case of composite services, the set of applicable constraints is derived from the service constraints defined over the individual service components that are part of the service plan. During the execution of a composite service, a constraint-aware composite service execution model can be used to manage and eventually operationally verify the service constraints prior to the corresponding service's execution. In addition to service constraints, other constraints might be imposed to put externally-defined restrictions on composite services. Such externally-defined restrictions are likely to be defined and become or cease to be applicable after the composite service has been assemble and deployed. Such a situation requires adaptation of the plan to a set of externally-defined constraints. Current web service composition adaptation approaches only focus on adaptation to failure in functional capabilities or Quality of Service (QoS) properties which can be dealt with re-construction of the composite service. However, we argue that adaptation to external constraints does not necessarily require changes in the plan of a composite service. In this paper, we define a constraint-based composite service model that not only considers service constraints, but also adapts composite plans according to new constraints that might add new restriction to the composite service at run time. A publicly available test set generator is used to compare the proposed solution with other existing service adaptation solutions.
Dynamic Spectrum Access Scheme of Variable Service Rate and Optimal Buffer-Based in Cognitive Radio

Dynamic spectrum access (DSA) scheme in Cognitive Radio (CR) can solve the current problem of scarce spectrum resource effectively, in which the unlicensed users (i.e. Second Users, SUs) can access the licensed spectrum in opportunistic ways without interference to the licensed users (i.e. Primary Users, PUs). However, SUs have to vacate the spectrum because of PUs coming, in this case the spectrum switch occurs, and it leads to the increasing of SUs’ delay. In this paper, we proposed a Variable Service Rate (VSR) scheme with the switch buffer as to real-time traffic (such as VoIP, Video), in order to decrease the average switch delay of SUs and improve the other performance. Different from previous studies, the main characteristics of our studying of VSR in this paper as follows: 1) Our study is on the condition of real-time traffic and we establish three-dimension Markov model; 2) Using the internal optimization strategy, including switching buffer, optimizing buffer and variable service rate; 3) As to the real-time traffic, on the condition of meeting the Quality of Service(QoS) on dropping probability, the average switch delay is decreased as well as improving the other performance. By extensive simulation and numerical analysis, the performance of real-time traffic is improved greatly on the condition of ensuring its dropping probability. The result fully demonstrates the feasibility and effectiveness of the variable service rate scheme.
Characterization of poly ( caprolactone ) / hydroxyapatite composite scaffolds produced by a melt extrusion additive manufacturing technique

P. Coimbra, J. P. Almeida, A. C. Santos*, S. Pereira, H. P. Cunha, B. Oliveiros, C. Capela, T. F. Viana, N. M. Alves and M. M. Figueiredo CIEPQPF, Chemical Engineering Department, University of Coimbra, Coimbra, Portugal Biophysics and Biomathematics Institute, IBILI-Faculty of Medicine, University of Coimbra, Coimbra, Portugal Department of Mechanical Engineering, ESTG, Polytechnic Institute of Leiria, Leiria, Portugal CEMUC, University of Coimbra, Coimbra, Portugal Centre for Rapid and Sustainable Product Development, Polytechnic Institute of Leiria (IPL), Marinha Grande, Portugal