Miracle-dz/UniFAR-FTUs huggingface dataset:
A Network Traffic Prediction Model Based on Quantum Inspired Pso and Wavelet Neural Network

Network traffic flow prediction model is fundamental to the network performance evaluation and the design of network control scheme which is crucial for the success of high-speed networks. Aiming at shortcoming of the conventional network traffic time series prediction model and the problem that BP training algorithms easily plunge into local solution, a network traffic prediction model based on wavelet neural network and PSO-QI is presented in the paper. Firstly, the quantum principle obtained from Quantum PSO(QPSO)has been combined with standard PSO to form a new hybrid algorithm called PSO with Quantum Infusion(PSO-QI). Then, the parameters of wavelet neural network were optimized with PSO-QI and the time series of network traffic data was modeled and predicted based on wavelet neural network and PSO-QI. Experiments showed that PSOQI-wavelet neural network has better precision and adaptability compared with the traditional neural network.
COMPARING ADOLESCENT AND MIDDLE-AGE GROUPS ON SPATIAL TASK PERFORMANCE: A DEVELOPMENTAL-DIFFERENTIATION APPROACH

Adolescent boys and girls were compared with middle-aged men and postmenopausal women on their performance on 3-dimensional space perception test. Results indicate that sex difference was evident only for the adolescent group and not for the middle-aged. Adolescent boys performed significantly better compared to girls. Age difference on spatial task performance was obtained only for males and not for females where postmenopausal women outperformed adolescent girls. Findings are explained in terms of progressive hemispheric lateralization and psychological differentiation across the life span.
Global marine gravity from retracked Geosat and ERS‐1 altimetry: Ridge segmentation versus spreading rate

Three approaches are used to reduce the error in the satellite‐derived marine gravity anomalies. First, we have retracked the raw waveforms from the ERS‐1 and Geosat/GM missions resulting in improvements in range precision of 40% and 27%, respectively. Second, we have used the recently published EGM2008 global gravity model as a reference field to provide a seamless gravity transition from land to ocean. Third, we have used a biharmonic spline interpolation method to construct residual vertical deflection grids. Comparisons between shipboard gravity and the global gravity grid show errors ranging from 2.0 mGal in the Gulf of Mexico to 4.0 mGal in areas with rugged seafloor topography. The largest errors of up to 20 mGal occur on the crests of narrow large seamounts. The global spreading ridges are well resolved and show variations in ridge axis morphology and segmentation with spreading rate. For rates less than about 60 mm/a the typical ridge segment is 50–80 km long while it increases dramatically at higher rates (100–1000 km). This transition spreading rate of 60 mm/a also marks the transition from axial valley to axial high. We speculate that a single mechanism controls both transitions; candidates include both lithospheric and asthenospheric processes.
Keyskills for all? The key skills qualification and Curriculum 2000

It is widely recognized that the Key Skills Qualification - an important component of the Curriculum 2000 advanced level curriculum reforms - has experienced extensive problems during its first full year of implementation. This much is not in dispute. What is being keenly debated, however, are the ways in which this experience should be analysed and what lessons should be drawn. Is it a case of understandable ‘teething problems’ that will be overcome as the qualification ‘beds in’ or are there deeper and more fundamental problems of the purpose and design of the Key Skills Qualification for advanced level students? In order to address these questions, this article examines the Key Skills Qualification within its historical and policy context as well as bringing together a range of quantitative and qualitative evidence gathered as part of an Institute of Education (IOE)/Nuffield Foundation R esearch Project. The research suggests that while there is support for the concept of key skills, the Qualification has been met with considerable student and professional resistance due to its narrow skills focus and assessment regime within the context of increased study programmes at advanced level. We conclude that the Government's aim of ‘key skills for all’ at advanced level is unlikely to be achieved unless it takes a fundamentally different approach to policy in this area.
The role of citizenship performance in academic achievement and graduate employability

Purpose – Employability is a major educational goal, but employability programmes emphasise skill development, while employers value performance. Education acts as a model for employment, so educational performance assessment should be aligned with employment models. Consequently, the aim of this paper is to examine the relationship between educational and workplace performance, especially the role of Citizenship Performance within educational settings.Design/methodology/approach – Students in an introductory university course rated their own personality, and weeks later assessed one another's Citizenship Performance. The relationship of these ratings to academic Task Performance was analysed with structural equation modelling.Findings – Citizenship Performance was correlated with academic Task Performance, at a similar level to that found in workplace studies. Further, Citizenship Performance mediated the prediction of Task Performance by the personality dimension Conscientiousness, a major predictor of .
Pro‐apoptotic effect of endogenous H2S on human aorta smooth muscle cells

Cystathionine gamma‐lyase (CSE) is a key enzyme in the trans‐sulfuration pathway, which uses L‐cysteine to produce hydrogen sulfide (H2S). The CSE/H2S system has been shown to play an important role in regulating cellular functions in different systems. In the present study, we overexpressed CSE in human aorta smooth muscle cells (HASMCs) using a recombinant defective adenovirus containing CSE gene (Ad‐CSE). Infection of HASMCs with Ad‐CSE resulted in a significant increase in the expression of CSE protein and H2S production. Ad‐CSE transfection inhibited cell growth and stimulated apoptosis, as evidenced by cell viability assay, Hoechst 33258 staining, TUNEL, and caspase 3 activation. CSE‐mediated apoptosis was associated with an increased ERK and p38 MAPK activation, up‐regulation of p21Cip/WAK‐1, and down‐regulation of cyclin D1 expression. After inhibiting endogenous background CSE gene expression, direct administration of H2S at 100 ? M induced apoptosis of HASMCs. The other two endproducts of CSE‐catalyzed enzymatic reaction, ammonium and pyruvate, failed to do so. These results demonstrate that overexpression of CSE stimulates SMC apoptosis due to an increased endogenous production of H2S. Adenovirus‐mediated transfer of CSE gene may provide a novel therapeutic approach in treating vascular diseases linked to abnormal cellular proliferation and vascular remodeling.
Facial Movement, Breathing, Temperature, and Affect: Implications of the Vascular Theory of Emotional Efference

The vascular theory of emotional efference (VTEE) states that facial action can alter the volume of air inhaled though the nose, which in turn in uences brain temperature and affective states. Cooling enhances positive affect, whereas warming depresses it. Three studies assessed this hypothesised series of effects. Study 1 found that when subjects engaged facial muscles in a manner analogous to a negative emotional expression, the volume of ambient air inhaled through the nose decreased, forehead temperature (a measure of brain temperature) increased, and participants reported feeling more negative affect. Study 2 established that prevention of nasal breathing generated negative affect. Study 3 indicated that forehead temperature increased when nasal breathing was prevented, without forehead muscle movement. Further, facial movement and prevention of nasal inhalation had no effects on arm temperature, showing that facial movement has only locally speci ® c temperature effects. The hypotheses generated from VTEE were thus generally supported, and suggest a means by which facial action can cause changes in affective state in the absence of cognitive appraisal. COGNITION AND EMOTION, 1997, 11 (2), 171± 195
Coffee Consumption, Newly Diagnosed Diabetes, and Other Alterations in Glucose Homeostasis: A Cross-Sectional Analysis of the Longitudinal Study of Adult Health (ELSA-Brasil)

Introduction Observational studies have reported fairly consistent inverse associations between coffee consumption and risk of type 2 diabetes, but this association has been little investigated with regard to lesser degrees of hyperglycemia and other alterations in glucose homeostasis. Additionally, the association between coffee consumption and diabetes has been rarely investigated in South American populations. We examined the cross-sectional relationships of coffee intake with newly diagnosed diabetes and measures of glucose homeostasis, insulin sensitivity, and insulin secretion, in a large Brazilian cohort of middle-aged and elderly individuals. Methods We used baseline data from 12,586 participants of the Longitudinal Study of Adult Health (ELSA-Brasil). Logistic regression analyses were performed to examine associations between coffee consumption and newly diagnosed diabetes. Analysis of covariance was used to assess coffee intake in relation to two-hour glucose from an oral glucose tolerance test, fasting glucose, glycated hemoglobin, fasting and –2-hour postload insulin and measures of insulin sensitivity. Results We found an inverse association between coffee consumption and newly diagnosed diabetes, after adjusting for multiple covariates [23% and 26% lower odds of diabetes for those consuming coffee 2–3 and >3 times per day, respectively, compared to those reporting never or almost never consuming coffee, (p = .02)]. An inverse association was also found for 2-hour postload glucose [Never/almost never: 7.57 mmol/L, ≤1 time/day: 7.48 mmol/L, 2-3 times/day: 7.22 mmol/L, >3 times/day: 7.12 mol/L, p<0.0001] but not with fasting glucose concentrations (p = 0.07). Coffee was additionally associated with 2-hour postload insulin [Never/almost never: 287.2 pmol/L, ≤1 time/day: 280.1 pmol/L, 2–3 times/day: 275.3 pmol/L, >3 times/day: 262.2 pmol/L, p = 0.0005) but not with fasting insulin concentrations (p = .58). Conclusion Our present study provides further evidence of a protective effect of coffee on risk of adult-onset diabetes. This effect appears to act primarily, if not exclusively, through postprandial, as opposed to fasting, glucose homeostasis.
Sex differences in distress: Real or artifact?

Women report greater distress than men, but do women genuinely experience greater distress, suggesting a heavier burden of hardship and constraint? Or do they merely report the feelings in standard indexes more frequently? Perhaps women discuss their emotions more freely. Or perhaps the indexes tap "feminine" emotions such as depression rather than "masculine" ones such as anger. This study analyzes data from a 1990 U.S. sample of 1,282 women and 749 men. Results show that men keep emotions to themselves more than women, and that women express emotions more freely than men. However, these factors do not explain the effect of sex on reported levels of distressan effect that remains significant with adjustment for these factors. Our results also contradict the idea that the sex difference in distress would diminish if the indexes of distress contained more items that tap anger Adjusting for emotional reserve and expressiveness, women experience anger more often than men, as they do sadness, anxiety, malaise, and aches. In fact, being female has twice the effect on the frequency of anger that it has on the frequency of sadness. Women report feeling happy as often as men, but adjusting for emotional expressiveness reveals a negative effect of being female on happiness. Overall, women experience distress about 30 percent more often than men. We discuss the possibility that drug abuse and heavy drinking mask male distress, but find little evidence that those behaviors ameliorate distress. We conclude that women genuinely suffer more distress than men.
Development of models and detection methods for different forms of cytomegalovirus for the evaluation of viral inactivation agents

BACKGROUND: Cytomegalovirus (CMV) is transmitted by transfusion of infected blood products and can cause serious diseases in specific risk groups. CMV can be present in infected blood as cell‐free virus (CFV), cell‐associated actively replicating virus (CAV), and cell‐associated latent virus (LV).
Interorganizational Relations: A Review of the Field.

the need for coordinated action in a society. As a consequence, improving relations between organizations has been a common concern of researchers and practitioners for decades. As the emphasis in organizational theory and research shifted in the 1960s from controlling internal activities to managing external constraints, discussions of resource control became prominent [47, 33]. The emphasis placed on the organization/environment interface during this period drew attention to the options available to organizations for increasing their control over the uncertainty of environmental exigencies. Chief among these options is collaborative agreements between organizations. The purpose of this article is to review the research conducted on these agreements. In the first half of the article we will review the different research traditions that have emerged in the field of interorganizational relations (IOR) and briefly discuss key studies conducted on different forms of IOR. In the second half of the article we will review one aspect of interorganizational relations, improving coordination, in greater detail because of its practical significance. In this section we will discuss the structural forms of coordination, antecedents of coordination, one specific model for improving coordination, and some of the unintended side effects of coordination.
Beyond the text: Illusions of recollection caused by script-based inferences

Three experiments investigated memory distortions produced by scripts activated when hearing a story. In Experiment 1, participants heard a story with one of two alternative titles. At test, the words that were falsely recognised varied according to the title of the story, though the story itself was the same for all participants. Experiment 2 replicated this effect and found that words rated as central to a script were more likely to be falsely recognised than words rated as peripheral. Participants in Experiment 3 heard a cryptic story with a disambiguating title presented either before, after, or not at all. Script-based errors were observed only in participants given the title before the story. In all three experiments, falsely recognised words were frequently categorised as “remember” responses, based on illusory conscious recollection. These findings show that inferences produce a powerful illusion of memory that is not simply due to verbal associations.
Fondaparinux vs. enoxaparin for the prevention of venous thromboembolism after total hip replacement: A meta-analysis

The aim of the study was to compare the efficacy and safety profiles of fondaparinux and enoxaparin in preventing the venous thromboembolism (VTE) after total hip replacement. A systematic literature search in the PubMed, EMBASE and Cochrane library databases was performed to identify relevant articles published in English since inception up to November 16, 2014. The efficacy outcomes were all VTE, total deep vein thrombosis (DVT) and symptomatic VTE, while the safety outcome was major bleeding. Four eligible studies were included in the meta-analysis. The incidences of total VTEs and DVTs were significantly decreased with the use of fondaparinux when compared to enoxaparin [total VTE: risk ratio (RR)=0.59, 95% confidence interval (CI): 0.46–0.74, P<0.01; total DVT: RR=0.58, 95% CI: 0.46–0.74, P<0.01]. Significantly fewer symptomatic VTEs and major bleeding cases were observed for the enoxaparin group (symptomatic VTE: RR=2.62, 95% CI: 1.07–6.45, P=0.04; major bleeding: RR=1.75, 95% CI: 1.20–2.53, P<0.01). In conclusion, the pooled analysis revealed that, compared to enoxaparin, fondaparinux was significantly more effective in preventing VTE after total hip replacements in terms of total VTEs and DVTs, although this was accompanied with an increased risk of major bleeding. However, the pooled analysis of two small sample trials from Japan failed to demonstrate any significant advantage for fondaparinux compared to enoxaparin.
Two families with phenotypically different hereditary low frequency hearing impairment: longitudinal data and linkage analysis

Two families with low frequency hearing impairment have been described previously. Family A (Danish) presented a sensorineural hearing impairment most pronounced for frequencies below 2 kHz and a pedigree typical for an autosomal dominant trait with complete penetrance (Königsmark type). Family B, originating from the Faroe Islands, showed conflicting audiological test results, making a valid classification impossible. The pedigree suggested autosomal dominant inheritance with incomplete penetrance. The objectives of the present study are to acquire longitudinal audiometric data, to clarify the mode of transmission, and to localize the mutant gene by re-evaluation of the two families. The methods used are evaluation of the family history, audiological examination and linkage analysis. In family A, update of the pedigree fitted the assumption of an autosomal dominant mode of transmission. In six examined subjects audiological data were available from the previous study. The median progression over a 13-21-year period was 13.8 dB HL for the thresholds, averaged across 0.5, 1, 2 and 4 kHz and 17.5 dB HL for the thresholds, averaged across 2 and 4kHz. In family B, the probable mode of transmission is autosomal dominant with reduced penetrance. In this family no progression of the hearing impairment was found. Linkage analysis of family A showed a lod score of 3.53, indicating significant linkage to the loci DFNA6 and DFNA14 on chromosome 4, previously found to be involved in low frequency hearing impairment. Family B was not linked to the region on chromosome 4, further adding to the genetic heterogeneity in low frequency sensorineural hearing impairment.
Comparison of fondaparinux and enoxaparin in acute coronary syndromes.

BACKGROUND The combined use of anticoagulants, antiplatelet agents, and invasive coronary procedures reduces ischemic coronary events but also increases bleeding in patients with acute coronary syndromes. We therefore assessed whether fondaparinux would preserve the anti-ischemic benefits of enoxaparin while reducing bleeding. METHODS We randomly assigned 20,078 patients with acute coronary syndromes to receive either fondaparinux (2.5 mg daily) or enoxaparin (1 mg per kilogram of body weight twice daily) for a mean of six days and evaluated death, myocardial infarction, or refractory ischemia at nine days (the primary outcome); major bleeding; and their combination. Patients were followed for up to six months. RESULTS The number of patients with primary-outcome events was similar in the two groups (579 with fondaparinux [5.8 percent] vs. 573 with enoxaparin [5.7 percent]; hazard ratio in the fondaparinux group, 1.01; 95 percent confidence interval, 0.90 to 1.13), satisfying the noninferiority criteria. The number of events meeting this combined outcome showed a nonsignificant trend toward a lower value in the fondaparinux group at 30 days (805 vs. 864, P=0.13) and at the end of the study (1222 vs. 1308, P=0.06). The rate of major bleeding at nine days was markedly lower with fondaparinux than with enoxaparin (217 events [2.2 percent] vs. 412 events [4.1 percent]; hazard ratio, 0.52; P<0.001). The composite of the primary outcome and major bleeding at nine days favored fondaparinux (737 events [7.3 percent] vs. 905 events [9.0 percent]; hazard ratio, 0.81; P<0.001). Fondaparinux was associated with a significantly reduced number of deaths at 30 days (295 vs. 352, P=0.02) and at 180 days (574 vs. 638, P=0.05). CONCLUSIONS Fondaparinux is similar to enoxaparin in reducing the risk of ischemic events at nine days, but it substantially reduces major bleeding and improves long term mortality and morbidity. (ClinicalTrials.gov number, NCT00139815.).
Pemphigus and dyslipidaemia: a case–control study

1976; 104:652–6. 6 Bessen DE, Sotir CM, Readdy TL et al. Genetic correlates of throat and skin isolates of group A streptococci. J Infect Dis 1996; 173:896– 900. 7 Lizano S, Luo F, Bessen DE. Role of streptococcal T antigens in superficial skin infection. J Bacteriol 2007; 189:1426–34. 8 Fiorentino TR, Beall B, Mshar P et al. A genetic-based evaluation of the principal tissue reservoir for group A streptococci isolated from normally sterile sites. J Infect Dis 1997; 176:177–82.
Phase I randomized double-blind placebo-controlled single-dose safety studies of Bowman-Birk inhibitor concentrate

In previously performed animal studies and Phase I–II human trials, Bowman-Birk inhibitor concentrate (BBIC) appeared to be a promising cancer chemopreventive agent. The present study describes the results of two phase I randomized double-blind placebo-controlled trials performed in male subjects to assess the safety and toxicity of the original and new formulations of BBIC administered in a single dose as a suspension in orange juice. The dose of BBIC varied from 800–2,000 chymotrypsin inhibitor (CI) units. The BBI concentration in the serum samples collected from the subjects was analyzed by a dot-blot analysis procedure using the 5G2 monoclonal antibody, which is specific for reduced BBI. A total of 41 subjects were enrolled, 20 in the initial BBIC study and 21 in the second BBIC study. In these human trials, no clinically relevant changes in hematological or biochemical parameters were observed. Overall, BBIC was found to be well-tolerated. For these BBIC single-dose phase I trials, there was no dose-limiting toxicity for BBIC, even at the highest dose evaluated, and there were no apparent differences between the clinical trial results for the two formulations of BBIC. The bioavailability of BBI in the second clinical trial, which used the new BBIC formulation, was approximately 40 to 43% of the BBI bioavailability reached in the first clinical trial, which used the original BBIC formulation. The observed bioavailability difference was attributed to the different BBIC formulations used in these two clinical trials. These trials demonstrated that BBIC is safe when administered in a single dose of up to 2,000 CI units. Therefore, the results from the two trials indicate that a multi-dose trial of BBIC may be safely performed with doses of up to 2,000 CI units per day.