Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis of the decision-making process of nurse managers: a collective reflection.

OBJECTIVE to analyze the decision-making model adopted by nurses from the perspective of some decision-making process theories. METHOD qualitative approach, based on action research. Semi-structured questionnaires and seminars were conducted from April to June 2012 in order to understand the nature of decisions and the decision-making process of nine nurses in position of managers at a public hospital in Southern Brazil. Data were subjected to content analysis. RESULTS data were classified in two categories: the current situation of decision-making, which showed a lack of systematization; the construction and collective decision-making, which emphasizes the need to develop a decision-making model. CONCLUSION the decision-making model used by nurses is limited because it does not consider two important factors: the limits of human rationality, and the external and internal organizational environments that influence and determine right decisions.
The implementation of accrual basis accounting by Indonesia’s local governments

ABSTRACT To examine the implementation of accrual basis accounting by local governments in Indonesia following its mandatory introduction by Government Regulation (GR) Number 71 of 2010, we identify key actors in the process. Local governments earn either a ‘qualified opinion’ or an ‘unqualified opinion’ in audited financial report. They all state that the implementation of the accrual basis accounting in their governments is limited to the production of accrual accounting reports only. The process itself is not accrual-based, even four years after its mandatory implementation. Technical issues, such as imprecise valuations and shortages of qualified staff, plague governments regardless of their qualified or unqualified rating. Given that only 16 officials from nine local governments are interviewed and given that neither BPK auditors nor the local auditors are interviewed on the progress made by local governments in implementing the accrual basis accounting, the results of this study cannot be generalized. Indonesia joins other countries in accepting accrual basis accounting. Little or no research looks at the progress since 2015. We do that, and we compare the progress made by the governments earning unqualified opinion rating with that made by the governments earning qualified opinion.
Essential Role for Vacuolar Acidification in Candida albicans Virulence*

Background: V-ATPase is responsible for establishing electrochemical gradients through energy-dependent proton transport. Results: In Candida albicans, mutation of vph1 resulted in defective phenotypic switching and avirulence in a murine septicemia model. Conclusion: The vacuolar specific isoform Vph1 is essential for vacuolar acidification and virulence in Candida albicans. Significance: Acidification of the vacuole plays a unique role in fungal virulence and growth phenotype. Fungal infections are on the rise, with mortality above 30% in patients with septic Candida infections. Mutants lacking V-ATPase activity are avirulent and fail to acidify endomembrane compartments, exhibiting pleiotropic defects in secretory, endosomal, and vacuolar pathways. However, the individual contribution of organellar acidification to virulence and its associated traits is not known. To dissect their separate roles in Candida albicans pathogenicity we generated knock-out strains for the V0 subunit a genes VPH1 and STV1, which target the vacuole and secretory pathway, respectively. While the two subunits were redundant in many vma phenotypes, such as alkaline pH sensitivity, calcium homeostasis, respiratory defects, and cell wall integrity, we observed a unique contribution of VPH1. Specifically, vph1Δ was defective in acidification of the vacuole and its dependent functions, such as metal ion sequestration as evidenced by hypersensitivity to Zn2+ toxicity, whereas stv1Δ resembled wild type. In growth conditions that elicit morphogenic switching, vph1Δ was defective in forming hyphae whereas stv1Δ was normal or only modestly impaired. Host cell interactions were evaluated in vitro using the Caco-2 model of intestinal epithelial cells, and murine macrophages. Like wild type, stv1Δ was able to inflict cellular damage in Caco-2 and macrophage cells, as assayed by LDH release, and escape by filamentation. In contrast, vph1Δ resembled a vma7Δ mutant, with significant attenuation in host cell damage. Finally, we show that VPH1 is required for fungal virulence in a murine model of systemic infection. Our results suggest that vacuolar acidification has an essential function in the ability of C. albicans to form hyphae and establish infection.
Universiteit Leiden Opleiding Wiskunde & Informatica Predicting the Risk of Overload in Overcommitted

The Virtual Machine Placement (VMP) problem is the problem of ﬁnding an optimal assignment of virtual machines (VMs) to physical server clusters. Platform as a Service (PaaS) providers - companies that rent out server space - try to ﬁt as many VMs as possible on the available physical servers, but need to consider a risk of overload on these servers. Therefore, when an assignment is made, the (highly dynamic) utilization of VMs should be considered. This work will characterize the utilization of VMs as accurately as possible while considering the needs for real-time adjustment and assessment of current conﬁgurations, limiting the complexity of the proposed solutions. We will characterize the utilization for 1) pre-existing VMs and 2) new VMs. These characterizations will be used to implement a model for quick risk assessment for possible assignments of VMs to server clusters. The proposed method will be evaluated on real life utilization traces provided by the Dutch IT company KPN.
How Important is Industry-Specific Managerial Experience for Innovative Firm Performance?

This study examines how industry-specific managerial experience affects firms’ innovation performance in the context of different institutional environments. Based on firm-level data from 27 Central and Eastern European countries we identify a robust positive relationship between industry-specific experience of the top-manager and the decision to innovate as well as the share of new product-related sales. These effects are particularly pronounced for small firms operating outside the European Union or, more generally, in institutionally less developed countries. The results suggest that managerial experience affects firm innovations largely indirectly, for example, by reducing uncertainty about future returns on innovations or by providing knowledge about how to cope with institutional shortfalls potentially hampering the commercial success of new products.
Blasts in transient leukaemia in neonates with Down syndrome differentiate into basophil/mast‐cell and megakaryocyte lineages in vitro in association with down‐regulation of truncated form of GATA1

Mutations of GATA1, leading to aberrant expression of a truncated form of GATA1 (called GATA1s), are present in transient leukaemia (TL) in neonates with Down syndrome. Using these molecular markers of TL, we investigated the growth and differentiation potential of TL blasts in the presence of hematopoietic growth factors (HGFs). Interleukin‐3, stem cell factor and granulocyte‐macrophage colony‐stimulating factor potently stimulated the growth of TL blast progenitors and induced differentiation towards basophil/mast cell lineages, whereas thrombopoietin induced differentiation towards megakaryocytes. GATA1s was expressed in TL blasts in all five patients examined but was down‐regulated during differentiation induced by these HGFs, while full‐length GATA1 was not expressed throughout the culture. GATA1 mutations were detected in TL blasts in four patients, including one patient with two distinct mutations. The cells of this patient exhibited identical and only mutated sequences both before and after culture with HGFs, confirming the leukemic cell origin of these differentiated cells. Erythroid differentiation of TL blasts was not evident with any HGFs. These data indicate that TL blasts have the potential to grow and differentiate towards particular hematopoietic lineages in the presence of specific HGFs and that the down‐regulation of GATA1s might be involved in blast cell differentiation.
Power spectrum-based fingerprint vitality detection

Despite its importance, a few works have been proposed for fingerprint vitality detection. In this paper, we propose a novel feature for detecting the "liveness" of fingerprint images. This feature is derived from the image power spectrum, and point out the difference between "live " and "fake" images in terms of high frequency information loss. Preliminary results on a large data set show the effectiveness of the proposed measure.
Spinal lesion level, shunt status, family relationships, and psychosocial adjustment in children and adolescents with spina bifida myelomeningocele.

Investigated whether family functioning and child psychosocial adjustment were associated with spinal lesion level and shunt status in 65 children and adolescents with spina bifida myelomeningocele (age range = 8-16). Mothers of children with higher lesion levels (i.e., thoracic level) reported more attachment to their children, less family conflict, and a greater willingness to grant autonomy to their offspring. Such findings support a "marginality" interpretation of the data, insofar as the least physically impaired children with spina bifida exhibited the greatest family difficulties. Based on maternal report, children with shunts performed more poorly in school and exhibited lower levels of cognitive competence than children without shunts. Findings are discussed in relation to literatures on neuropsychological functioning and psychosocial adjustment in children with spina bifida.
A Controller Design for an Axial Flow Blood Pump Based on Back-EMF without Delay

The article mainly focused on the design of the control system based on C8051F330 to control the speed of an axial flow blood pump. On one hand the terminal voltage comparison was used to recognize the rotor position; on the other hand in order to capture the edge of position signal, the external interrupt0 of the MCU was used that can reduce the interference that came from the axial flow blood pump. The results of the experiment showed that the phase differences of the position signals were 60 electrical degrees, which coincide with the classical theory, Back-EMF crossing-zero sensing method. And the periodic time of the position signal was about 6.7 ms, the corresponding speed was 8,955 RPM that nearly equal to the reference speed 9,000 RPM. Therefore the result demonstrated that by utilizing this control system the blood pump could be driven steplessly without bounce or losing step. The control system had the following advantages: small volume, simple structure, high reliability, favorable speed performance, and low power consumption. Hence, this control system was qualified for the axial flow blood pump.
Protein secretion in Escherichia coli.

INTRO DUCT I ON . 615 MODELS OF PROTEIN E XPORT . 6 1 7 STR UCT URE AND FUN CTION O F THE SIGNAL SE QUEN CES . 620 The Basic Amino-Terminus 624 The Hydrophobic Core . 624 The Processing Site . 628 ROLE OF MATURE PROTEIN SEQUENCES IN EXPORT . 629 Periplasmic Proteins. 629 Outer Membrane Proteins . 630 Inner Membrane Proteins . 632 CELL ULAR E XPORT MA CHINERY . 633 Biochemical Studies . 633 Genetic Studies . 637 CON CL UDI NG REMARKS . 643
Practical approach for estimation of subcutaneous and visceral adipose tissue

Objectives: The first objective was to investigate the correlations between anthropometrical measurements and visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) in two cohorts differing in age using magnetic resonance imaging (MRI) as reference. A second objective was to investigate the potential usage of abdominal diameters in practical estimation of adipose tissue compartments using these cohorts.
Different intracellular mechanisms underlie testosterone's suppression of basal and stimulation of cyclic luteinizing hormone release in male and female rats.

The aromatase inhibitor 1,4,6-androstatriene- 3,17-dione (ATD), a nonsteroidal antiandrogen (flutamide), testosterone and estradiol were administered by Silastic capsule or injection to ovariectomized female and castrate and intact male rats. The treatments were given separately or in combination to investigate the relative importance of elevations in nuclear estrogen receptor levels in hypothalamic and preoptic area target neurons for the expression of several of testosterone's neuroendocrine actions. These actions include the suppression of basal LH secretion, the stimulation of cyclic LH release, the induction of lordosis behavior, and the regulation of progestin receptor levels. Estrogen receptor levels were measured in purified nuclear pellets from the hypothalamus, preoptic area, and adenohypophysis with an in vitro [3H]estradiol exchange assay. Progestin receptors were quantified in cytosol preparations of these tissues using the synthetic progestin [3H]R5020. When exposed to t stosterone levels of.
Characterization of Pseudomonas aeruginosa phage K5 genome and identification of its receptor related genes

Phage genomic information and the nature of host‐phage interactions are important for phage applications. In this study, Pseudomonas aeruginosa phage K5 is characterized as a linear double‐stranded genomic DNA molecule of 93,754 bp with identical 1182‐bp direct terminal repeats. Comparative genomic analysis reveals that phage K5 is highly homologous to the “PaP1‐like” phages. Thirteen mutants resistant to phage K5 are screened in a transposon mutant library. The disrupted genetic loci are identified as gene Y880_RS05480 encoding a putative O‐antigen polymerase Wzy and gene wapH encoding a glycosyltransferase. The mutants are confirmed by the complementation experiment. The production of biofilm and the profile of lipopolysaccharide (LPS) are further analyzed in the Y880_RS05480 mutant. Our data indicate that LPS is the receptor of phage K5.
Fuzzy compensation for nonlinear friction in a hard drive

This paper presents the fuzzy control approach to compensate for nonlinear friction in a hard-disk drive. The dynamic of the read/write head at low-frequency is significantly affected by the nonlinearity and friction caused by the nonlinear damping characteristic of the data flex and the pivot bearing of the voice-coilmotor. Nonlinear dynamic models of the head are given. Design of the fuzzy controller as well as simulation results are presented. The step response of the closed-loop fuzzy control exhibits no overshoot, and settles within 1.6 msec. Key-Words: fuzzy control, read/write head, nonlinear friction
The ‘healthy immigrant’ effect: initial evidence for Ireland

Abstract The period from 1996 to 2008 was one of rapid economic and social change in Ireland, with one of the most significant changes being the transition from a situation of net emigration to one of substantial net immigration. Although research on the impact of immigration on Irish society, as well as the labour market characteristics and experiences of immigrants in Ireland has increased in recent years, comparatively little is known about the health status of immigrants to Ireland. An extensive international literature has documented a ‘healthy immigrant’ effect for large immigrant-receiving countries such as the United States, Canada and Australia, whereby the health status of immigrants is better than comparable native-born individuals. There is also evidence to suggest that immigrants’ health status deteriorates with time spent in the host country. However, the Irish immigration experience differs considerably from that of countries that have been the focus of research on the ‘healthy immigrant’ effect. Using microdata from a nationally representative survey of the population in 2007, this paper finds only limited evidence in favour of a ‘healthy immigrant’ effect for Ireland, although the distinctive features of the Irish immigrant population, and the nature of the data available, may partly explain the results.
Recent divergence between two morphologically differentiated subspecies of bluethroat (Aves: Muscicapidae: Luscinia svecica) inferred from mitochondrial DNA sequence variation

We assessed the mitochondrial DNA sequence divergence of a 718 bp fragment of the control region and 1007 bp of the cytochrome b gene between two allopatric morphologically different subspecies of bluethroat (Luscinia svecica). None of the 17 total haplotypes was shared between L. s. namnetum and L. s. svecica. However, the mean distances between subspecies were very low for both fragments (0.00168 ± 0.00001 (mean ± SE) for the control region; 0.00306 ± 0.00016 for the cytochrome b gene). Only one substitution made the two subspecies genetically differentiated, highlighting their recent divergence. Interestingly, the control region was not more variable than the cytochrome b gene.
“Hoilet System”— A Way to Improve Experience in High Traffic Female Public Restrooms in the U.S

This paper focuses on improving the experience of women using high traffic public restrooms in the U.S. By looking into the past studies on the insufficient numbers of ladies’ rooms provided under building codes and the lack of accommodations for multi-tasking, with further research on public restroom cleanliness and personal privacy, this paper proposes that all four of those contribute to an unpleasant experience. At the same time, little has been done to address these problems nationwide and most of the relevant research is out of date. To further understand the overall experience women go through, a survey was conducted and analyzed. The results highlight concerns on cleanliness and skin contact, the need for accommodation on tasks other than elimination, and the compromise of privacy in a public environment. These unmet need also are related to the delays in use and waiting time. By concluding these findings, this paper argues that it is the lack of research and investigation which impedes the progress of both design and legislation. Therefore, this paper poses that: first, further study is needed on what contributes to these factors in public restrooms and how it could be applied to the redesign of the public restrooms, thus a fundamental research base could be provided for legislators, designers, and architects; second, a clean and convenient public toilet design, “Hoilet System”, could be applied in public restrooms to address these problems.
Rational Versus Intuitive Gatekeeping: Escalation of Commitment in the Front End of NPD

The unwillingness of a gatekeeper to let go of a fruitless new product development (NPD) project wastes valuable resources and hampers NPD performance. The onset of such escalation of commitment is likely to occur already in the front end of NPD, where high ambiguity and complexity make it hard to distinguish fruitless from potentially successful projects. This study investigates if a gatekeeper's thinking style-whether they think rationally or whether they follow their intuition-can prevent escalation of commitment in the front end. Theory on cognition provides arguments for and against either thinking style's influence on escalation of commitment, but empirical evidence on this matter is lacking. Our study demonstrates that gatekeepers who think rationally are less likely to escalate their commitment than those who follow their intuition. This result holds both in a correlational study of dispositional thinking styles, as well as in an individual-level randomized experiment in which the thinking style of experienced practitioners before they take gate decisions is induced. Our findings provide ample opportunities for improving existing front end gate review practices, such as allocating candidates for gatekeeper positions based on their thinking style, training gatekeepers to think rationally, and increasing the use of gate-decision rules and templates.
The organization of the rating system for assessing the quality of university students training

In spite the universities use the rating system of assessing for a quite long time, this issue is still not fully considered. The article is based on the position of insufficient state of knowledge of the multifunctionality of the students rating. The rating helps to reveal the potential of students. It is mentioned that the rating system of assessment is a tool that will improve the quality of training and provide the required level of motivation. During the research, the following methods were used: analysis, synthesis, induction, deduction. As a result, the principles of the rating assessment system were revealed, a definition of the term "Rating" was given, its goals were indicated. As an example of the organization of the rating system of assessment, the Nyzhnii Novhorod State Pedagogical University and its "Regulations on the rating system for assessing the quality of student training" were used. It is noted that the rating includes: current check, midterm and final examinations. Further, all possible conditions under which the student receives points were identified and considered. On the example of the NSPU named after Kozma Minin transferring of the rating points into a five-point grading rating system is presented. Also, the types of violations for which points are discarded, are considered. As the study showed, comprehensive planned system yields productive results for students and the university.
Can I leave this one out?: the effect of dropping an item from the SUS

There are times when user experience practitioners might consider using the System Usability Scale (SUS), but there is an item that just doesn't work in their context of measurement. For example, the first item is "I think I would like to use this system frequently. " If the system under study is one that would only be used infrequently, then there is a concern that including this item would distort the scores, or at best, distract the participant. The results of the current research show that the mean scores of all 10 possible nine-item variants of the SUS are within one point (out of a hundred) of the mean of the standard SUS. Thus, practitioners can leave out any one of the SUS items without having a practically significant effect on the resulting scores, as long as an appropriate adjustment is made to the multiplier (specifically, multiply the sum of the adjusted item scores by 100/36 instead of the standard 100/40, or 2.5, to compensate for the dropped item).