Miracle-dz/UniFAR-FTUs huggingface dataset:
Aspectising honeytokens to contain the insider threat

The aim of this study is to provide a generic implementation strategy for honeytokens deployed within a database management system that leverages the aspect-oriented paradigm to contain the insider threat. This approach is tested by developing a proof-of-concept prototype in an aspect-oriented language, namely AspectJ. This study also reflects on design and implementation challenges involved in the deployment of honeytokens to contain the insider threat. Consequently, aspect-orientation is proposed as a means to resolve some of these challenges.
DSP-Based Approach to Generating Computer Model of Impulse Noise Using Kernel Data Sequence

In this paper, we present a new computer model to simulate the impulse-type noise that appears in bursts on a high- voltage (HV) power line during transient and emergency situations. The computer model is designed for investigations of the effects of impulse noise on communication channels implemented over an HV power line. The simulation process relies on an authentic record of measured noise whose modified replicas we use to compose a train of short-time impulses evenly distributed in time. The recorded noise sequence is referred to as a kernel data sequence over which we apply digital-signal-processing (DSP) techniques to randomize its length and its amplitudes. Noise impulses produced by the simulator achieve and retain the sharp front ends and spectral properties of the original noise. A variable digital filter is implemented to examine the influences of impulse noise on communication channels. Performances of simulated noise have been compared with those of measured noise published in CIGRÉ, IEEE, and IEC documents. Comparisons demonstrate a good agreement between the characteristics of measured and simulated noise.
Japanese road signs recognition using neural networks

Recently, traffic accidents are increasing because of driver's inattentiveness to the road signs. In this work, in order to assist drivers, we propose a recognition system for road signs using neural networks. We first segment road sign regions using color and shape features to get the location information. The initial sign recognition uses template matching. However, since this did not produce satisfactory results, a neural network is used to learn and recognize the signs. A variety of features are considered for training the neural network. The experimental results show that this recognition method is effective for online road sign recognition.
Long-Term Extracorporeal Photoimmunotherapy for Treatment of Chronic Cutaneous Graft-versus-Host Disease: Observations in Four Patients

Background: Chronic cutaneous graft-versus-host disease (GvHD) can arise as a late complication after allogeneic bone marrow transplantation. Patients with extensive disease to date require intensive early and long-term immunosuppression; however, treatment is often insufficient. Since the beneficial effects of phototherapy for chronic cutaneous GvHD are well known, extracorporeal photoimmunotherapy (ECP) was also tried with some success for a few single patients with this disease. Objective: The long-term effect of ECP was evaluated in 4 patients with therapy-resistant severe chronic cutaneous GvHD after allogeneic bone marrow transplantation. Methods: Four patients were treated with monthly sessions of ECP over a period of 16–40 months. Disease severity was assessed by a semiquantitative score adapted from the literature including extent of skin area involved, rigidity of the skin, involvement of joints and immunosuppressive drug consumption. Results: In all patients, a favorable response was observed after 6–12 treatment cycles. One patient had a complete response, 2 patients had a partial response, and 1 patient had a minor response after treatment. In 2 patients, immunosuppressive medication started before initiating ECP could be reduced or completely withdrawn under ECP. Peripheral blood lymphocyte immunophenotyping revealed reduction of CD3+ CD4+ T cells in 3 patients and of elevated CD3+ CD8+ and CD57+ CD8+ T cell subsets in 2 patients. Conclusion: ECP is effective in treating severe chronic cutaneous GvHD. ECP possibly exerts its effects by reducing the number of CD8+ suppressor/cytotoxic T cells, the presumptive effector cells of GvHD. ECP is well tolerated with essentially no side effects and allows reducing the dosage of immunosuppressive agents.
Visual Discrimination Task Improvement: A Multi-Step Process Occurring During Sleep

Performance on a visual discrimination task shows longterm improvement after a single training session. When tested within 24 hr of training, improvement, was not observed unless subjects obtained at least 6 hr of postraining sleep prior to retesting, in which case improvement was proportional to the amount of sleep in excess of 6 hr. For subjects averaging 8 hr of sleep, overnight improvement was proportional to the amount of slow wave sleep (SWS) in the first quarter of the night, as well as the amount of rapid eye movement sleep (REM) in the last quarter. REM during the intervening 4 hr did not appear to contribute to improvement. A two-step process, modeling throughput as the product of the amount of early SWS and late REM, accounts for 80 percent of intersubject variance. These results suggest that, in the case of this visual discrimination task, both SWS and REM are required to consolidate experience-dependent neuronal changes into a form that supports improved task performance.
An Approach for Online Assessment of Rooftop Solar PV Impacts on Low-Voltage Distribution Networks

Assumption-based offline analysis tools may not be able to provide sufficient and accurate information for the corrective decision making to mitigate solar photovoltaic (PV) impacts in the future distribution grids. This is mainly due to the increasing penetration level of intermittent power generation resources and also the fluctuating behavior of consumer demand. Online assessment tools can assist to manage PV impacts and aid to mitigate those on a real-time basis. This paper proposes an approach for online assessment of rooftop PV impacts on low-voltage (LV) networks using real-time network data. A variable-width sliding window will be used to provide the analysis an outcome-based online data. The width of the sliding window can be varied according to user input so that the changes in network behavior caused by PV integration can be investigated conveniently. Several numerical indices are proposed in this paper to assess solar PV impacts on the LV networks. This approach also uses the online data to develop real-time distribution network models for a dynamic “what-if” analysis. The usefulness of the proposed online assessment approach is verified using an Australian LV distribution feeder.
Fast speech recognition to access a very large list of items on embedded devices

In this paper, we propose a fast decoding algorithm to recognize a very large number of item names on a resource-limited embedded device. The proposed algorithm is based on a multi-pass search scheme. The algorithm is composed of a two-stage HMM-based coarse match and a detailed match. The two-stage HMM-based coarse match is aimed at rapidly selecting a small set of candidates that are assumed to contain a correct hypothesis with high probability, and the detailed match re-ranks the candidates by performing acoustic rescoring. The proposed algorithm is implemented on an in-car navigation system with a 32-bit fixed-point processor operating at 620 MHz. The experimental result shows that the proposed method runs at maximum speed 1. 74 times real-time on the embedded device while minimizing the degradation of the recognition accuracy for a 220 K Korean Point-of-Interest (POI) recognition domain.
Melanoma differentiation associated gene-7/interleukin-24 reverses multidrug resistance in human colorectal cancer cells

Overexpression of the multidrug resistance 1 (MDR1) gene, encoding P-glycoprotein (P-gp), facilitates resistance to diverse chemotherapeutic drugs and current P-gp inhibitors display high toxicity. We studied the effects of melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24), which exhibits cancer-specific apoptosis-inducing properties, in drug-sensitive (SW620) and drug-resistant (SW620/Dox) colorectal carcinoma cells. Adenovirus administered mda-7/IL-24, Ad.mda-7, effectively reversed resistance to doxorubicin-induced apoptosis in SW620/Dox cells by increased intracellular accumulation and decreased efflux of doxorubicin. Unexpectedly, P-gp–overexpressing cells (SW620/Dox) displayed increased apoptosis following Ad.mda-7 infection compared with parental SW620 cells, which correlated with more MDA-7/IL-24 protein in SW620/Dox than SW620 cell and potentially explains the increased sensitivity of P-gp–overexpressing cells to mda-7/IL-24. Transient overexpression of MDR1 in SW620 cells significantly increased apoptosis, decreased anchorage-independent growth, and increased MDA-7/IL-24 protein following Ad.mda-7 infection, whereas down-modulation of MDR1 in SW620/Dox cells by small interfering RNA decreased apoptosis following Ad.mda-7 infection. The increased mda-7/IL-24 sensitivity observed in SW620/Dox cells was partly due to increased reactive oxygen species generation and lower mitochondrial membrane potential. These findings confirm that mda-7/IL-24 is a potent MDR reversal agent, preferentially causing apoptosis in P-gp–overexpressing MDR cells, suggesting significant expanded clinical implications for the use of mda-7/IL-24 in treating neoplasms that have failed chemotherapy mediated by the P-gp MDR mechanism. [Mol Cancer Ther 2007;6(11):2985–94]
Improved differential evolution algorithm with decentralisation of population

Differential evolution (DE) is a reliable and versatile function optimiser especially suited for continuous optimisation problems. Practical experience, however, shows that DE easily looses diversity and is susceptible to premature and/or slow convergence. This paper proposes a modified variant of DE algorithm called improved differential evolution (IDE). It works in three phases: decentralisation, evolution and centralisation of the population. Initially, the individuals of the population are partitioned into several groups of subpopulations (decentralisation phase) through a process of shuffling. Each subpopulation is allowed to evolve independently from each other with the help of DE (evolution phase). Periodically, the subpopulations are merged together (centralisation phase) and again new subpopulations are reassigned to different groups. These three phases helps in searching all the potential regions of the search domain effectively, thereby, maintaining the diversity. The promising nature of IDE is demonstrated on a testbed of 16 benchmark problems having box constraints. Comparison of numerical results shows that IDE is either better or at par with other contemporary algorithms.
Mechanism design of a new multifingered robot hand

A new five-finger robot hand (NTU hand) with seventeen degrees of freedom (DOF) is developed in this paper. In contrast to traditional tendon-driven robot, the NTU hand has an uncoupled configuration such that each finger and joint are all individually driven. While all actuators, mechanical parts and sensors are packed on the hand, the size of NTU hand is almost the same as a human hand. Such compact design makes the hand easily adapt to industrial robot arms and prosthetic applications. According to the mechanical structure of the NTU hand, the direct and inverse kinematics are also developed in this paper.
Analysis of the frequency of microsatellite instability and p53 gene mutation in splenic marginal zone and MALT lymphomas.

AIMS: Studies of the genetic characteristics of splenic marginal zone lymphoma (SMZL) have failed to identify genetic changes specific to this tumour. Microsatellite instability is a type of genomic instability associated with different types of human cancer. Although microsatellite instability is rare in B cell non-Hodgkin's lymphomas, it has been found in some specific subsets, such as marginal zone lymphomas arising in mucosa associated lymphoid tissue (MALT), where an association with p53 mutation has been described. Because it has been proposed that SMZL and MALT are close in histogenetic terms, this study investigated the comparative frequency of microsatellite instability and p53 mutation in patients with SMZL and MALT lymphomas. METHODS: Microsatellite instability was investigated using seven microsatellite marker loci in 14 patients with SMZL and 20 patients with MALT lymphomas. In an attempt to clarify the role of p53 gene mutation in the pathogenesis of SMZL, exons 5-8 were also investigated by polymerase chain reaction single strand conformation polymorphism (PCR-SSCP) and direct sequencing in a total of 20 patients with SMZL and 22 patients with MALT lymphomas. RESULTS: Microsatellite instability was not detected in patients with SMZL, although five of 20 patients with MALT lymphomas had microsatellite instability. The frequency of p53 mutation was low in both series (two of 20 patients with SMZL and one of 22 patients with MALT lymphomas). No significant association was found between p53 mutation and microsatellite instability. CONCLUSIONS: These results indicate that microsatellite instability is not associated with the molecular pathogenesis of SMZL, confirming the relatively increased frequency of microsatellite instability in MALT lymphomas, and perhaps suggesting that MALT and SMZL have different mechanisms of tumorigenesis.
Body temperature and thermoregulation during submaximal exercise after 115-day spaceflight.

BACKGROUND Altered thermoregulation has been reported following spaceflight simulations (bed rest and water immersion) but has never been examined after actual spaceflight. HYPOTHESIS We tested the null hypothesis that body temperatures and heat loss responses during exercise would be similar before and after spaceflight. METHODS Two male crewmembers of the 115-d Mir 18 mission performed supine submaximal cycle exercise (20 min at 40% and 20 min at 65% of preflight VO2peak) once at 145-146 d preflight and once at 5 d postflight (R + 5). RESULTS After flight neither crewmember could complete the exercise protocol, stopping after 28-29 min. The core temperature (Tin, ingestible telemetry pill) at test termination was similar (37.8 degrees C for both subjects) pre- and postflight despite shorter postflight test duration. The slopes of the skin blood flow (laser Doppler)/Tin relationship (subject 1: 396 vs. 214; subject 2: 704 vs. 143% change Perfusion Unit/degree C), and the sweating rate (dew point hygrometry)/Tin relationship (subject 1: 6.3 vs. 2.0; subject 2: 4.6 vs. 0.7 mg.min-1.cm-2.degree C-1), were both reduced postflight without appreciable change in the Tin thresholds for sweating or skin blood flow. CONCLUSION In this preliminary report for two crewmembers, the sensitivity of the heat loss responses were reduced after long-duration spaceflight, resulting in a faster rate of rise in core temperature.
Clinical and socio‐cultural parameters in Nigerian psychiatric patients

ABSTRACT– Three hundred and eighteen consecutive new patients presenting at a psychiatric unit in Yorubaland were prospectively studied. The majority were young, and the sexes were equally represented. Most patients came from within 50 km of the unit. Most were brought by their blood‐relatives. Significant delay before presentation was observed in most cases. Previous treatment by religious and/or traditional healers was common. According to the DSM‐III classification, the majority suffered from functional psychoses, most commonly schizophrenia. Three quarters received neuroleptic medication. The immediate clinical outcome was good in the majority of cases; however, within 6 months of presentation almost half defaulted from treatment. Variables which appeared to be related to delay in presentation, prior treatment by religious or traditional healers and defaulting are presented.
Eighth-Mode Substrate Integrated Resonator Antenna at 2.4 GHz

In this letter, a linearly polarized eighth-mode substrate integrated waveguide (EMSIW) resonator antenna that operates at 2.42 GHz and can be used for commercial wireless LAN applications has been proposed. In comparison to its SIW resonator counterpart, this structure is reduced to 1/8 of its size, while still retaining competent performance characteristics and simple design. The proposed structure has been simulated using CST MWS to obtain the frequency response and radiation characteristics. This EMSIW antenna has dominant resonant frequency at 2.42 GHz and radiates with a gain around 5 dBi. The effect of variation of ground plane width has been studied. The structure has been implemented on FR-4 substrate, and the simulated and measured results are in good agreement.
Tracking the dynamics of secondary degeneration after stroke

Further evidence of diffusion tensor imaging contribution in the characterisation of retrograde and anterograde degeneration after stroke The advent of diffusion tensor imaging (DTI)–MRI allows direct in vivo visualisation of white matter fibre tracts, opening a window on the important issue of functional connectivity in normal human brain. Furthermore, it provides a tool for measurement of fibre tract integrity in diseases of the central nervous system. Thus it is becoming possible to assess in a single patient whether specific fibre tracts will escape damage and also to relate these changes to clinical outcome. In particular, the application of DTI to the study of retrograde/anterograde degeneration of white matter pathways secondary to focal ischaemia may provide new insights into the mechanisms implicated in loss as well as recovery of function after stroke. In this issue, two articles have applied DTI to investigate the time course and clinical correlates of secondary degeneration after subcortical stroke involving the motor pathway in patients who were prospectively studied over 3 months (within 1 week, 4 weeks and 12 weeks after stroke). To date, few data were available …
Construction d'une loi de comportement isotrope transverse pour la simulation du thermoformage de thermoplastiques chargées de fibres

Cet article traite de la construction d'un modele de comportement hyperelastique isotrope transverse et de son application a la simulation par elements finis du procede de thermoformage de materiaux charges de fibres. Dans un premier temps, nous developpons l'expression generale de l'energie de deformation en terme d'invariants tensoriels prenant en compte l'anisotropie induite par les fibres. Puis, pour illustrer notre approche, nous presentons la simulation par elements finis d'un cas de thermoformage simple, mettant en evidence la perte de symetrie due aux fibres.
Full-dimensional MIMO for future cellular networks

Full-dimensional multiple input multiple output (FD-MIMO) is a practical implementation of massive MIMO in cellular communication systems. FD-MIMO relies on an active two-dimensional antenna grid at the base stations and harvests the benefits of both azimuth and elevation beamforming. This paper briefly introduces the concept of FD-MIMO, and surveys the recent research results and applications of active antenna systems (AAS) technology. The key concepts discussed range from antenna patterns and channel modeling to vertical sectorization and heterogeneous networks deployment. The paper focuses on the benefits of FD-MIMO in an urban environment with high rises and three-dimensional user deployment. It demonstrates the importance of FD-MIMO in enhancing the performance of cellular networks.
Faktor-Faktor yang Mempengaruhi Pengintegrasian Teknologi Pengajaran Berdasarkan Model TPACK dalam Kalangan Guru Matematik

Kajian ini secara umumnya mengkaji faktor-faktor yang mempengaruhi pengintegrasian teknologi pengajaran berdasarkan model TPACK dalam kalangan guru matematik. TPACK adalah singkatan bagi “Technology Pedagogy Content Knowledge” . Fokus kajian ini tertumpu kepada pengetahuan teknologi, pengetahuan pedagogi dan pengetahuan kandungan dalam kalangan guru matematik. Bagi mencapai objektif ini, penyelidik telah memilih seramai 120 orang responden dari kalangan guru matematik sekolah menengah di Daerah Kubang Pasu sebagai sampel kajian. Kajian ini berbentuk tinjauan keratan rentas yang bersifat kuantitatif dengan menggunakan soal selidik sebagai instumen kajian bagi tujuan mengenal pasti faktor-faktor yang mempengaruhi pengintegrasian teknologi pengajaran berdasarkan model TPACK. Dapatan kajian telah menunjukkan bahawa guru-guru di sekolah menengah di Daerah Kubang Pasu, mempunyai min pengetahuan pedagogi dan min pengetahuan kandungan pada tahap yang tinggi tetapi min pengetahuan teknologi berada pada tahap yang sederhana. Secara keseluruhannya keputusan kajian menunjukkan bahawa faktor-faktor yang mempengaruhi pengintegrasian teknologi pengajaran berdasarkan model TPACK berada pada tahap yang sederhana. Sehubungan dengan itu, penyelidik mencadangkan agar guru-guru matematik di daerah Kubang Pasu diberikan latihan tentang penggunaan teknologi supaya kemahiran teknologi dapat dipertingkatkan dan seterusnya dapat menjayakan proses pengintegrasian teknologi pengajaran berdasarkan model TPACK. Semoga dengan ini, proses pengajaran dan pembelajaran matematik menjadi lebih bermakna dan mampu menarik minat seterusnya memberi motivasi kepada pelajar meningkatkan prestasi disamping menggalakkan guru-guru matematik memperluaskan lagi penggunaan ICT di sekolah.
Temperature effects on haemostasis in whole blood from ticagrelor- and aspirin-treated patients with acute coronary syndrome

Abstract Background. Comatose survivors after cardiac arrest are treated with mild induced hypothermia and potent platelet- inhibiting drugs after coronary stenting. Previous studies have shown an increased incidence of stent thrombosis during clopidogrel and aspirin treatment in conjunction with induced hypothermia. The aim of this study was to investigate the in vitro effect of induced hypo- and hyperthermia on blood from patients undergoing ticagrelor- and aspirin-mediated platelet inhibition. Methods. Whole blood from 15 patients with acute coronary syndrome who were treated with ticagrelor and aspirin and from eight healthy volunteers was incubated for 1 hour at 28, 33, 37, and 39°C. Results. In blood from patients with acute coronary syndrome, the activated clotting time (Sonoclot) was prolonged in mild hypothermic (33°C) compared to normothermic (37°C) samples. Sonoclot, clotting rate and platelet function were decreased in hypothermic compared to normothermic samples. Platelet-induced activation and aggregation (Multiplate®) was unchanged in mild hypothermic compared to normothermic samples. In contrast, mild hypothermia supported increased platelet activation as measured with flow cytometry with up-regulation of PAC-1 and P-selectin on the platelet surface. Conclusion. In acute coronary syndrome patients treated with ticagrelor and aspirin, in vitro hypothermia to 33°C markedly increased platelet activity measured with flow cytometry, whereas viscoelastic coagulation test (Sonoclot) revealed a hypocoagulative response. Prospective clinical trials studying platelet inhibition at different temperatures and correlating changes in platelet function to bleeding or stent occlusion are needed.