Miracle-dz/UniFAR-FTUs huggingface dataset:
Mineral contents of selected marine fish and shellfish from the west coast of Peninsular Malaysia

The study was conducted to determine the mineral contents of 20 species of marine fish and 4 species of shellfish from the west coast of Peninsular Malaysia.Overall, the contents of micro minerals in all samples were below the permissible limits; except for oyster; with copper slightly higher than the limit set by FAO/WHO (1984), but below the limit set by Malaysian Food Regulations (1985); and zinc content higher than the limit set by Malaysian Food Regulations (1985), but below the limit set by FAO/WHO (1984). Meanwhile for macro minerals, most samples contained comparable sodium contents, significantly lower of potassium contents, higher calcium contents, and extremely higher of magnesium contents compared to the common ranges reported in the literatures. All samples were good sources of micro and macro minerals and could provide multi-health benefits if consumed in recommended amounts.
Band selection based on feature weighting for classification of hyperspectral data

A new feature weighting method for band selection is presented, which is based on the pairwise separability criterion and matrix coefficients analysis. Through decorrelation of each class by principal component transformation, the criterion value of any band subset is the summations of the values of individual bands of it for the transformed feature space, and thus the computation amounts of calculating criteria of each band combinations are reduced. Following it, the corresponding matrix coefficients analysis is done to assign weights to original bands. As feature weighting considers little about the spectral correlation, the redundant bands are removed by choosing those with lower correlation coefficients than a preset threshold. Hyperspectral data classification experiments show the effectiveness of the new band selection method.
Design, synthesis and antiproliferative activity of hydroxyacetamide derivatives against HeLa cervical carcinoma cell and breast cancer cell line

Purpose : To design and develop a new series of histone deacetylase inhibitors (FP1 - FP12) and evaluate their inhibitory activity against hydroxyacetamide (HDAC) enzyme mixture-derived HeLa cervical carcinoma cell and MCF-7. Methods : The designed molecules (FP1 - FP12) were docked using AUTODOCK 1.4. 6. FP3 and FP8 showed higher interaction comparable to the prototypical HDACI. The designed series of 2-[[(3- Phenyl/substituted Phenyl-[4-{(4- (substituted phenyl)ethylidine-2-Phenyl-1,3-Imidazol-5-One}](-4H- 1,2,4-triazol-5-yl)sulfanyl]-N-hydroxyacetamide derivatives (FP1-FP12) was synthesized by merging 2- [(4-amino-3-phenyl-4H- 1, 2, 4-triazol-5-yl) sulfanyl]- N-hydroxyacetamide and 2-{[4-amino-3-(2- hydroxyphenyl)-4H-1,2, 4-triazol-5-yl]sulfanyl}-N hydroxyacetamide derivatives with aromatic substituted oxazolone. The biological activity of the synthesized molecule (FP1-FP12) was evaluated against HDAC enzyme mixture-derived HeLa cervical carcinoma cell and breast cancer cell line (MCF-7). Results: HDAC inhibitory activity of FP10 showed higher IC50 (half-maximal concentration inhibitory activity) of 0.09 μM, whereas standard SAHA molecule showed IC50 of 0.057 μM. On the other hand, FP9 exhibited higher GI50 (50 % of maximal concentration that inhibited cell proliferation) of 22.8 μM against MCF-7 cell line, compared with the standard, adriamycin, with GI50 of (-) 50.2 μM. Conclusion : Synthesis, spectral characterization, and evaluation of HDAC inhibition activity and in vitro anticancer evaluation of novel hydroxyacetamide derivatives against MCF-7 cell line have been achieved. The findings indicate the emergence of potentialanticancer compounds. Keywords : Molecular docking, Hydroxyacetamide derivative, Histone deacetylase inhibition activity, MCF-7 cell line
Paeoniflorin Promotes Non-rapid Eye Movement Sleep via Adenosine A1 Receptors

Paeoniflorin (PF, C23H28O11), one of the principal active ingredients of Paeonia Radix, exerts depressant effects on the central nervous system. We determined whether PF could modulate sleep behaviors and the mechanisms involved. Electroencephalogram and electromyogram recordings in mice showed that intraperitoneal PF administered at a dose of 25 or 50 mg/kg significantly shortened the sleep latency and increased the amount of non-rapid eye movement (NREM). Immunohistochemical study revealed that PF decreased c-fos expression in the histaminergic tuberomammillary nucleus (TMN). The sleep-promoting effects and changes in c-fos induced by PF were reversed by 8-cyclopentyl-1,3-dimethylxanthine (CPT), an adenosine A1 receptor antagonist, and PF-induced sleep was not observed in adenosine A1 receptor knockout mice. Whole-cell patch clamping in mouse brain slices showed that PF significantly decreased the firing frequency of histaminergic neurons in TMN, which could be completely blocked by CPT. These results indicate that PF increased NREM sleep by inhibiting the histaminergic system via A1 receptors.
The influence of masculine, feminine, and neutral tasks on children's achievement behavior, expectancies of success, and attainment values.

STEIN, ALETHA HUSTON; POHLY, SHEILA RIMLAND; and MVELLER, EDWARD. The Influence of Masculine, Feminine, and Neutral Tasks on Children's Achievement Behavior, Expectancies of Success, and Attainment Values. CHILD DEVELOPMENT, 1971, 42, 195-207. The study tested the hypothesis that children's attainment values (AV), expectancies of success (Exp), and achievement behavior (time spent on a task) would be greatest on a sex-appropriate test, intermediate on a neutral test, and least on a sex-inappropriate test. 96 sixth-grade boys and girls were given 3 tests introduced as measures of masculine, feminine, and neutral skills. For boys, the hypothesis was strongly supported on all measures. For girls, A V and Exp scores were approximately equal on the feminine and neutral tests, but significantly lower on the masculine test; girls' time scores on the 3 tests
LIMSI-CNRS@CLEF 2015: Tree Edit Beam Search for Multiple Choice Question Answering

This paper describes our participation to the Entrance Ex- ams Task of CLEF 2015's Question Answering Track. The goal is to an- swer multiple-choice questions on short texts. Our system rst retrieves passages relevant to the question, through lexical expansion involving WordNet and word vectors. Then a tree edit model is used on graph representations of the passages and answer choices to extract edit se- quences. Finally, features are computed from those edit sequences and used in various machine-learned models to take the nal decision. We submitted several runs in the task, one of which yielding a c@1 of 0.36, which makes our team the second best on the task.
Task Scheduling Algorithm for Sporadic Tasks in Single-ISA Heterogeneous Multi-Core Architectures *

Single-ISA Heterogeneous Multi-Core Architectures Yen-Ting Huang, Yi-Jung Chen, and Dyi-Rong Duh Department of Computer Science and Information Engineering National Chi Nan University Puli, Nantou Hsien 54561, Taiwan {s98321504, yjchen}@ncnu.edu.tw Department of Computer Science and Information Engineering Hwa Hsia Institute of Technology 111, Gong Jhuan Rd., New Taipei City 23568, Taiwan drduh@cc.hwh. edu.tw
The Activity of Immunoglobulin Y Anti-Mycobacterium tuberculosis on Proliferation and Cytokine Expression of Rat Peripheral Blood Mononuclear Cells

Objective: It has long been known that chickens, like mammals, are capable of producing antigen-specific immunoglobulin Y (IgY), which functions similar to IgG. The present study was performed to investigate the activity of IgY anti-Mycobacterium tuberculosis on proliferation, interleukin (IL)-2, and interferon (IFN)-γ expression of rat peripheral blood mononuclear cells (PBMCs). Materials and Methods: The activity of IgY anti-M. tuberculosis in different doses (25, 50, and 100 μg/ml) on rat PBMCs proliferation was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay. The production of IL-2 and IFN-γ in the PBMC supernatant was determined using enzyme-linked immunosorbent assay. Investigation was performed on mRNA expression of IL-2 and IFN-γ by reverse transcription-polymerase chain reaction (RT-PCR). Results: IgY anti-M. tuberculosis significantly increased the proliferation of rat PBMC. Furthermore, IgY anti-M. tuberculosis dose dependently increased IL-2 and IFN-γ production in PBMC, suggesting that pharmacological activities of IgY anti-M. tuberculosis in PBMC may be mediated by regulating the production of cytokines. In the RT-PCR, expression of cytokines such as IL-2 and IFN-γ in PBMC cultures was increased by IgY anti-M. tuberculosis. Conclusions: We concluded that increasing IL-2 and IFN-γ productions in PBMC was related to IgY anti-M. tuberculosis, stimulating the mRNA transcription (gene expression) of these cytokines which can induce proliferation of PBMC.
A Controlled Trial of Cognitive–Behavioural Treatment of Hypochondriasis

Background Hypochondriasis is a distressing disorder for which there is no adequate established treatment. This study evaluates the effect of cognitive–behavioural treatment of hypochondriasis, compared with a waiting list control. Method Thirty-two patients were randomly assigned to either cognitive–behavioural therapy or a no treatment waiting list control. Cognitive–behavioural treatment consisted of 16 individual treatment sessions over a four-month period. The waiting list control lasted for four months and was followed by 16 sessions of cognitive–behavioural treatment. Assessments were made before allocation and after treatment or waiting list control. Patients who had cognitive–behavioural treatment were reassessed three months after completion of treatment. Results Paired comparisons on post-treatment/wait scores indicated that the cognitive–behavioural group showed significantly greater improvements than the waiting list on all but one patient rating, all therapist ratings and all assessor ratings. After three months the benefits of therapy were maintained. Conclusions Cognitive–behavioural treatment is an effective therapy for hypochondriasis. Implications of the study are discussed.
Wideband Dual-Polarized Crossed-Dipole Antenna with Parasitical Crossed-Strip for Base Station Applications

A wideband dual-polarized crossed-dipole antenna with parasitical crossed-strip for base- station applications is presented. By using a pair of orthogonal crossed-dipoles, two linear polarizations (§45 - ) are obtained. A parasitical crossed-strip is introduced to improve the impendence bandwidth and enhance the isolation (S12) between the two orthogonal polarizations of the upper band. The antenna shows a wideband impedance characteristic about 34.9% for S11 • i10dB (+45 - polarization) and S22 • i10dB (i45 - polarization). High isolation (S12 • i32dB) between the two polarizations in the required band are obtained. The stable peak gain, unidirectional radiation patterns and low cross- polarization over the whole operating band are also achieved. Due to its good performance, simple fabrication technique and low cost, the antenna is very suitable for potential base station applications in mobile communication such as DCS, PCS and UMTS.
A 170 GHz 45$^{\circ}$  Hybrid for Submillimeter Wave Sideband Separating Subharmonic Mixers

We present a 135deg/45deg phase shifter hybrid intended to be used in subharmonic sideband separation mixer schemes at submillimeter-wave frequencies. The design consists of an increased height 90deg 6-arm branch guide coupler with a three stub loaded differential line 45deg phase shifter at the output. The device has been implemented at G-band in an E-plane WR-05 splitblock design with a center frequency of 170 GHz and 15 % bandwidth. Measured S-parameter are in good agreement with simulations showing an isolation and return loss better than 20 dB and an amplitude and phase imbalance within 0.4 dB and 2deg, respectively.
Structure and Function of Papiliocin with Antimicrobial and Anti-inflammatory Activities Isolated from the Swallowtail

Jin-Kyoung Kim, Eunjung Lee, Soyoung Shin, Ki-woong Jeong, Jee-Young Lee, Su-Young Bae, Soo-Hyun Kim, Juneyoung Lee, Seong Ryul Kim , Dong Gun Lee, Jae-Sam Hwang , and Yangmee Kim From the Department of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul 143-701, the Laboratory of Cytokine Immunology, Institute of Biomedical Science and Technology, College of Medicine, Konkuk University, Seoul 143-701, the School of Life Sciences and Biotechnology, College of Natural Sciences, Kyungpook National University, Daegu 702-701, and the National Academy of Agricultural Science, Rural Development Administration, Suwon 441-100, South Korea
Firing Properties of Identified Interneuron Populations in the Mammalian Hindlimb Central Pattern Generator

Little is known about the network structure of the central pattern generator (CPG) controlling locomotor movements in mammals. The present experiments aim at providing such knowledge by focusing on commissural interneurons (CINs) involved in left–right coordination. During NMDA and 5-HT-initiated locomotor-like activity, we recorded intracellularly from caudally or descending projecting L2 and L3 CINs (dCINs) located in the ventromedial area of the lumbar spinal cord in newborn rats. This region is crucial for rhythmic motor output and left–right coordination. The overall sample of dCINs represented a heterogenous population with neurons that fired in all phases of the locomotor cycle and exhibited varying degrees of rhythmicity, from strongly rhythmic to nonrhythmic. Among the rhythmic, putative CPG dCINs were populations that fired in-phase with the ipsilateral or with the contralateral L2 locomotor-like activity. There was a high degree of organization in the dorsoventral location of rhythmic dCINs, with neurons in-phase with the ipsilateral L2 activity located more ventrally. Spikes of rhythmically active dCINs were superimposed on membrane oscillations that were generated predominantly by synaptic input, with little direct contribution from the intrinsic pacemaker hyperpolarization-activated inward current. For both ipsilaterally and contralaterally firing dCINs the dominant synaptic drive was in-phase with the ipsilateral L2 motor activity. This study provides the first characterization of putative CPG interneurons in the mammalian spinal cord. Our results suggest an anatomical and physiological separation of CPG commissural interneurons in the ventral horn and demonstrate that it is possible to target specific interneuron subpopulations in the mammalian locomotor network.
Effects of Velocity-Based Resistance Training on Young Soccer Players of Different Ages

Abstract González-Badillo, JJ, Pareja-Blanco, F, Rodríguez-Rosell, D, Abad-Herencia, JL, del Ojo-López, JJ, and Sánchez-Medina, L. Effects of velocity-based resistance training on young soccer players of different ages. J Strength Cond Res 29(5): 1329–1338, 2015—This study aimed to analyze the effect of velocity-based resistance training (RT) with moderate loads and few repetitions per set combined with jumps and sprints on physical performance in young soccer players of different ages. A total of 44 elite youth soccer players belonging to 3 teams participated in this study: an under-16 team (U16, n = 17) and an under-18 team (U18, n = 16) performed maximal velocity RT program for 26 weeks in addition to typical soccer training, whereas an under-21 team (U21, n = 11) did not perform RT. Before and after the training program, all players performed 20-m running sprint (T20), countermovement jump (CMJ), a progressive isoinertial loading test in squat to determine the load that elicited a ∼1 m·s−1 velocity (V1LOAD) and an incremental field test to determine maximal aerobic speed (MAS). U16 showed significantly (p = 0.000) greater gains in V1LOAD than U18 and U21 (100/0/0%). Only U16 showed significantly (p = 0.01) greater gains than U21 (99/1/0%) in CMJ height. U18 obtained a likely better effect on CMJ performance than U21 (89/10/1%). The beneficial effects on T20 between groups were unclear. U16 showed a likely better effect on MAS than U21 (80/17/3%), whereas the rest of comparisons were unclear. The changes in CMJ correlated with the changes in T20 (r = −0.49) and V1LOAD (r = 0.40). In conclusion, velocity-based RT with moderate load and few repetitions per set seems to be an adequate method to improve physical performance in young soccer players.
QSPR Treatment of the Soil Sorption Coefficients of Organic Pollutants

In this study, general and class-specific QSPR models for soil sorption, logK(OC), of 344 organic pollutants (0 < logK(OC) < 4.94) were developed using a large variety of theoretical molecular descriptors based only on molecular structure. Two general models were obtained. The first model was derived for a structurally representative set of 68 chemicals (R2=0.76, s=0.44), whereas the second involved a total of 344 compounds (R2=0.76, s=0.41). The first was validated using the data for the remaining 276 pollutants (R2=0.70, s=0.45). An additional validation of both models was performed using an independent set of 48 pollutants. Both models predict the logK(OC) at the level of experimental precision, while the theoretical molecular descriptors appearing in the QSPR models give further insight into the mechanisms of soil sorption. The analysis of the distribution of the residuals of the logK(OC) values calculated by both general models indicated the need and possible advantages of modeling soil sorption for smaller data sets related to individual classes of chemicals. Accordingly, QSPR models were also developed for 14 chemical classes. The descriptors appearing in these models were discussed as related to the possible interaction mechanisms in soil sorption.
Ready-set-transfer! Technology transfer in the requirements engineering domain (panel)

Though the primary goal of requirements engineering research is to propose, develop, and validate effective solutions for important practical problems, practice has shown that successful projects take from 20-25 years to reach full industry adoption, while many projects fade and never advance beyond the initial research phase. In this interactive panel, teams of researchers, representing different requirements engineering research areas, bring ideas for technology transfer to a panel of industrial and government practitioners. The teams make interactive presentations and receive feedback from panelists. Beneath the game-show genre of the panel is the serious goal to foster conversation between practitioners and researchers to improve the effectiveness of technology transfer in the requirements engineering community.
Uneven illumination removal based on fully convolutional network for dermoscopy images

For the dermoscopy image, uneven illumination will influence segmentation accuracy and lead to wrong aided diagnosis result. In this paper, an uneven illumination removal method based on deep learning is proposed for dermoscopy images. Different from the traditional Retinex based methods, which estimate the illumination component using statistical methods to obtain the reflectance component of the image (uneven illumination removal result), in this paper, the illumination component is regarded as a black box to be learned by a designed fully convolutional neural network(FCN) model. The designed FCN model has more scales and can mine more effective features to obtain good illumination correction results. Experiment results show that, compared with 7 other state-of-art algorithms, our method can remove uneven illumination more effectively, and with our method, the segmentation performance is improved greatly.
Unsupervised splitting rules for neural tree classifiers

The authors present two unsupervised neural network splitting rules for use with CART-like neural tree algorithms in high-dimensional data space. These splitting rules use an adaptive variance estimate to avoid some possible local minima which arise in unsupervised methods. They explain when the unsupervised splitting rules outperform supervised neural network splitting rules and when the unsupervised splitting rules outperform the standard node impurity splitting rules of CART. Using these unsupervised splitting rules leads to a nonparametric classifier for high-dimensional space that extracts local features in an optimized way. <<ETX>>
Ethanolic extract of Piper betle Linn. leaves reduces nociception via modulation of arachidonic acid pathway

Objectives: The objective of this study was to evaluate the peripheral analgesic effect of Piper betle leaf extract (PBE) along with establishing its putative mechanism of action. Materials and Methods: Male Swiss albino mice after pre-treatment (1 h) with different doses of PBE were injected 0.8% (v/v) acetic acid i.p.; the onset and number of writhes were noted up to 15 min. To evaluate the mechanism of action, the murine peritoneal exudate was incubated with PBE for 1 h, followed by exposure to arachidonic acid (AA) and generation of reactive oxygen species (ROS) was measured by flow cytometry using 2’,7’-dichlorodihydrofluorescein diacetate. Results: PBE in a dose dependent manner significantly reduced acetic acid induced writhing response in mice (P < 0.001). In peritoneal exudates, PBE significantly inhibited AA induced generation of ROS, P < 0.01. Conclusions: The present study indicates that PBE has promising analgesic activity, worthy of future pharmacological consideration.
Searching for Head and Shoulders Bottom Patterns under Directional Changes

Head and Shoulder pattern is a well-known technical trading strategy. However, what exactly constitutes a Head and Shoulder pattern under time series is sometimes ambiguous. In this thesis, we show how this pattern can be rigorously defined by using Directional Change. Directional Change is a new way to summarise price changes in the market. It records a transaction price only when the market has moved in to an opposing direction by a significant degree , and where that margin of significant movement is defined by the observer. Unlike time series, Directional Change records data at irregular points. This thesis also shows how Head and Shoulder Bottom Patterns can be recognised by using Directional Change. Presenting a precise definition of Head and Shoulder pattern, therefore allows us to rigorously examine the effectiveness of a Head and Shoulder based trading strategy.
A High-Resolution Shape-Fragment MEDLA Database for Toxicological Shape Analysis of PAHs

A new, high-resolution shape-fragment database has been developed for computing ab initio quality molecular electron densities for polyaromatic hydrocarbons (PAHs) which play a significant role as toxicants in the environment. Using the new PAH electron density fragment database and the Molecular Electron Density Lego Assembler (MEDLA) method, one can generate detailed and reliable electron densities for virtually any of the PAH molecules. Accurate electron density shape representations for these molecules is essential in the study of detailed shape-toxicity correlations. One of our goals is to investigate the potential of detailed molecular shape analysis as a predictive tool in toxicological risk assessment. In this study we report the results of the first phase of the study: the construction and testing of a high quality shape-fragment database for PAHs.