Miracle-dz/UniFAR-FTUs huggingface dataset:
The Mouse Median Nerve Experimental Model in Regenerative Research

Sciatic nerve crush injury in rat animal model is one of the most common experimental models used in regenerative research. However, the availability of transgenic mouse for nerve regeneration studies is constantly increasing and, therefore, the shift from rat model to mouse model is, in some cases, necessary. Moreover, since most of the human nerve lesions occur in the upper limb, it is also advantageous to shift from sciatic nerve to median nerve. In this study we described an experimental model which involves lesions of the median nerve in the mouse. Data showed that the finger flexor muscle contraction strength, assessed to evaluate the motor function recovery, and reached values not different from the control already 20 days after injury. The degree of nerve regeneration evaluated with stereological methods in light microscopy showed that, 25 days after injury, the number of regenerated myelinated fibers was comparable to the control, but they were smaller with a thinner myelin thickness. Stereological analysis made in electron microscopy confirmed these results, although the total number of fibers quantified was significantly higher compared to light microscopy analysis, due to the very small size of some fibers that can be detected only in electron microscopy.
Low Overhead Ethernet Communication for Open MPI on Linux Clusters

This paper describes the basic concepts of our solution to improve the performance of Ethernet Communication on a Linux Cluster environment by introducing Reliable Low Latency Ethernet Sockets. We show that about 25% of the socket latency can be saved by using our simplified protocol. Especially, we put emphasis on demonstrating that this performance benefit is able to speed up the MPI level communication. Therefore we have developed a new BTL component for Open MPI, an open source MPI-2 implementation which offers with its Modular Component Architecture a nearly ideal environment to implement our changes. Microbenchmarks of MPI collective and Point-to-Point operations were performed. We see a performance improvement of 8% to 16% for LU and SP implementations of the NAS parallel benchmark suite which spends a significant amount of time in the MPI. Practical application tests with Abinit, an electronic structure calculation program, show that the runtime of be nearly halved on a 4 node system. Thus we show evidence that our new Ethernet communication protocol is able to increase the speedup of parallel applications considerably.
Experimental Analysis of Human Touch Activated Self-healing Body Energy: Gyoki Body Resonancing

Vidan Damljanovic erhielt sein Diplom als Physiotherapeut 1981 in Belgrad, Serbien, sein Diplom als Shiatsuterapeut 2007 am Kaiko Institut in Zürich, Schweiz und arbeitet und unterrichtet bis heute auf diesem Gebiet. Von 1983 bis 1988 arbeitete er an der Poliklinik Belgrad und von 1988 bis 1995 als Physiotherapeut am Krankenhaus Heiden, Heiden, Schweiz. Seit 1995 und bis heute leitet er eine Physiotherapiepraxis in Au, Schweiz. Er hat kontinuierlich verschiedene Fortbildungskurse zur Manuellen Therapie und MTT (Medizinische Trainingstherapie) in Europa und Japan besucht: u.a. Maitland, Cyriax, Mc Kenzie, Manuelle Therapiemethoden von Brian Mulligan, Propriozeptive Neuromuskuläre Facilitation (PNF) und Osteopathie. Dieser Spur folgend, hatte er einen starken Fokus auf Seiki und konzentriert sich dabei auf die Shiatsu-Physiotherapie. Er wendet Seiki täglich in seiner Praxis an und unterrichtet dieses Thema in verschiedenen Workshops in ganz Europa; begleitet von regelmäßigen Schulungen in Shiatsu und vor allem in Seiki bei Akinobu und Kyoko Kishi. Seit 2013 leitet Vidan Seiki Seminare. Außerdem unterrichtet und trainiert er seit mehr als 33 Jahren Kendo und leitet seit 1999 den Bushikan Kendo Club, Au, Schweiz, und nahm an mehreren Europaund Weltmeisterschaften teil.
Loneliness and Emotional Support Predict Physical and Psychological Distress in Latinas with Breast Cancer and Their Supportive Partners

Following predictions from the stress process model, associations between loneliness, emotional support, physical health, and psychological distress were tested in 115 Latinas with breast cancer and their supportive partners. Results showed that loneliness and emotional support were predictive of psychological distress and physical symptoms. Additionally, emotional support minimized the association between physical symptoms and psychological distress. There were strong individual-level effects for loneliness and emotional support on physical health and psychological distress, and evidence that a partner's loneliness also worsened psychological distress in the participants.
PREDICTION FOR CONDITION MONITORING OF WEAR AND FILM THICKNESS IN A GEAR BOX

Gears are used to transmit power and motion in mechanical, electrical and chemical process industries. Influenced by vibration, torque, temperature, lubrication & specific film thickness, the gear teeth contacts may experience change leading to unexpected failures such as wear, scuffing, pitting and micro-pitting on teeth surface. In order to avoid these damages, continuous monitoring is essential using knowledge based systems. Generic capability of artificial neural network (ANN) is exploited to formulate prediction and classification based on heuristic models of condition of lubricating oil in spur gears. Based on the loading conditions such as vibration, temperature and torque, the algorithm predicts film thickness to classify oil conditions as elastohydrodynamic (EHD), mixed wear and severe wear that helps in detecting faults in gear operation.
Feminist supervision and supervisee nondisclosure: The mediating role of the supervisory relationship

ABSTRACT In this study, the authors investigated the predictive relationship between a feminist supervisory approach and supervisee nondisclosure, along with the potential mediating effect of the supervisory relationship. Among a sample of master’s-level counseling interns (N = 111), supervisees who perceived more feminist behaviors from their supervisor were more likely to rank the supervisory relationship as stronger and were less likely to report withholding information from their supervisor. Furthermore, the supervisory relationship partially mediated the link between feminist supervision and supervisee nondisclosure. Implications for supervisors and researchers are discussed.
The Role of the Noradrenergic System in the Exploration–Exploitation Trade-Off: A Psychopharmacological Study

Animal research and computational modeling have indicated an important role for the neuromodulatory locus coeruleus–norepinephrine (LC–NE) system in the control of behavior. According to the adaptive gain theory, the LC–NE system is critical for optimizing behavioral performance by regulating the balance between exploitative and exploratory control states. However, crucial direct empirical tests of this theory in human subjects have been lacking. We used a pharmacological manipulation of the LC–NE system to test predictions of this theory in humans. In a double-blind parallel-groups design (N = 52), participants received 4 mg reboxetine (a selective norepinephrine reuptake inhibitor), 30 mg citalopram (a selective serotonin reuptake inhibitor), or placebo. The adaptive gain theory predicted that the increased tonic NE levels induced by reboxetine would promote task disengagement and exploratory behavior. We assessed the effects of reboxetine on performance in two cognitive tasks designed to examine task (dis)engagement and exploitative versus exploratory behavior: a diminishing-utility task and a gambling task with a non-stationary pay-off structure. In contrast to predictions of the adaptive gain theory, we did not find differences in task (dis)engagement or exploratory behavior between the three experimental groups, despite demonstrable effects of the two drugs on non-specific central and autonomic nervous system parameters. Our findings suggest that the LC–NE system may not be involved in the regulation of the exploration–exploitation trade-off in humans, at least not within the context of a single task. It remains to be examined whether the LC–NE system is involved in random exploration exceeding the current task context.
A Model for Automating Persistent Identity Clone in Online Social Network

Online Social Network (OSN), such as Face book, Linked In, Twitter, is today's one of the most popular platform on the internet where millions of users sign on daily to share personal information with friends and colleagues. On many of these services, users are able to share photos, videos, stories, send and receive messages, locations and play games. However, many OSNs have weak user to user authentication mechanism, mostly based on information such as displayed name, photo, and a set of common social links. This result in easy to exploit identity cloning attack to establish fake social link. In this paper, we develop a model to exploit OSN weak trust model and maintain authenticity of the fake online identity established by identity cloning attack to harvest more private information, and discuss how the attack can be thwarted and avoided by the users and developers of OSN. We develop an attack methodology to take advantage of a cloned fake profiles and carry authentic conversation between the exploited users. We also experiment with injecting various fake messages to harvest more information. Our experimental results show that the attack is feasible.
Intrapulmonary penetration of ceftolozane/tazobactam and piperacillin/tazobactam in healthy adult subjects.

OBJECTIVES Appropriate antibiotic exposure at the site of infection is important for clinically effective therapy. This study compared the epithelial lining fluid (ELF) penetration of ceftolozane/tazobactam, which has potent in vitro activity against many Gram-negative pathogens causing nosocomial pneumonia, with that of piperacillin/tazobactam in healthy adult volunteers. METHODS In this Phase 1, open-label trial, 51 healthy adult subjects were randomized to receive three doses of either ceftolozane/tazobactam 1.5 g administered every 8 h via a 60 min infusion or piperacillin/tazobactam 4.5 g administered every 6 h via a 30 min infusion. Serial blood samples were obtained for determination of plasma drug concentrations. Bronchoscopy and bronchoalveolar lavage were performed at pre-specified timepoints in five subjects per timepoint in each treatment group to determine the ELF drug concentration. The penetration of individual analytes into the ELF was determined from the ratio of the area under the plasma concentration-time curve in ELF to that in plasma (AUC(ELF)/AUC(plasma)). RESULTS Plasma and ELF concentrations of ceftolozane, piperacillin and tazobactam increased rapidly, reaching maximal concentrations at the end of the infusion. Mean maximum concentration and AUC from time 0 to the end of the dosing interval (AUC(0-τ)) for ceftolozane in ELF were 21.8 mg/L and 75.1 mg·h/L, respectively. Corresponding values for piperacillin were 58.8 mg/L and 94.5 mg·h/L. The ELF/plasma AUC ratio for ceftolozane was 0.48 compared with 0.26 for piperacillin. CONCLUSION This study demonstrated that ceftolozane penetrated well into the ELF following parenteral administration of ceftolozane/tazobactam.
The socio-economic boundaries shaping young people’s lunchtime food practices on a school day

This is the peer reviewed version of the following article: Wendy J. Wills, Giada Danesi, Ariadne B. Kapetanaki, and Laura K. Hamilton, ‘The Socio‐Economic Boundaries Shaping Young People's Lunchtime Food Practices on a School Day’, Children & Society, Vol. 32 (3): 195-206, May 2018, which has been published in final form at https://doi.org/10.1111/chso.12261. Under embargo until 6 April 2019. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
ACTIVE APPEARANCE MODEL SEARCH WITH MOTION COMPENSATION FOR 3D FACE TRACKING

In this paper, we propose a reliable active appearance model search for face and facial feature tracking. More precisely, two different feature-based schemes for global motion compensation have been proposed and integrated into the search algorithm. Tracking experiments show that the robustness and stability of the active appearance model search can be considerably improved with the inclusion of the proposed motion compensation schemes. The resulting 3D face tracking can find applications in many fields especially in the fields of human-computer interaction and model-based image coding.
Monitoring Costs and Offshoring with Heterogeneous Firms

We present a model in which monitoring costs determine firms’ outsourcing and offshoring decisions. We predict that the most productive firms outsource in the South, while the least productive produce in-house in the North. Within the range of intermediate productivities, firms with lower productivity outsource in the North, and those with higher productivity perform in-house production in the South. Offshoring gives rise to higher average world productivity, but an overall loss of variety. Exit of Southern firms following offshoring is sufficient to offset any change in the number of Northern firms producing ex post. Inequality between Northern entrepreneurs and Northern workers rises, while that between Northern workers and Southern workers falls. Inequality between Northern entrepreneurs and everyone else rises.
A Novel Integration Model for the Simulation of Kiln Landscape in Ancient Fu Liang Area

Re-creation of the land use transformation at different periods in time is valuable for revealing how policy change influence ancient Fu Liang kiln. To date, there has been little focused on the model of historical Fu Liang kiln change. On the contrary, current research has emphasized that the transformation process of kiln has been described by literal presentation. However, Dynamical and visual model can provide insights into kiln change processes and are valuable for land use transformation. For this reason, we create virtual maps of ancient Fu Liang area and propose such constructs to unambiguously denote a novel integration model. In this model, ancient virtual maps are created by ARCGIS10.0 software and PCI9.0 software, land use changes are performed through cellular automata, decision processes are controlled beyond the multi-agent, spatial optimization is represented by particle swarm optimization. We use the simulation approach to recreate the kiln transformation of Fu Liang, Jiang Xi, annually from 1271 to 1554. The simulation of the model is of richer changing hierarchy and can better reflect the whole process from the first to the last firing, and can be used to preferable create dynamic model and theory. Additionally, the model can better reflect the interaction of the political situation, institutions and the natural environment.
A Network Analysis of Stakeholders in Tool Visioning Process for Story Test Driven Development

Participation from all stakeholders is important in a successful software development project, especially if the development project is complex and has many stakeholders. Identifying the key stakeholders is very difficult in a large community-based open source development project, because a lot of conflicting ideas exist in the community and not all of the necessary stakeholders are represented in the discussions. We analyzed the homogeneity of the stakeholders in the story-test driven development tool community and the diversity of the opinions represented by the stakeholders. We gathered opinions from the agile software engineering community on a list of desired features in a story testing tool. Then we categorize the community using a social network analysis to analyze the consensus building process. The network analysis reveals that the community has several key people with dominant degree centrality in the social network and the tool development community is remarkably homogeneous. Our research shows that a social network analysis is a good way to analyze the characteristics of consensus reached during a product visioning process.
Inhibition of Zika Virus Replication by Synthetic Bis-Naphthoquinones

Zika virus (ZIKV) is a mosquito-borne pathogen which is a current global public health concern. There are currently no approved vaccines or antivirals against ZIKV infection. Taking into account that naphthoquinones have shown promising antiviral activity, the aim of this study was to describe the screening of two bis-naphthoquinones series against ZIKV. Twenty seven compounds were evaluated against ZIKV using Vero cells. The findings showed that among the compounds analyzed four were promising. Compound 3,3’-((2-nitrophenyl)methylene)bis(2-hydroxynaphthalene1,4-dione) containing the nitro group at the ortho position showed the best selectivity index, followed by compound 3,3’-(4-chlorophenylmethylene)bis(naphthalene-1,2,4-triyl triacetate) with the chlorophenylmethylene radical. These results demonstrate that these bis-naphthoquinones are largely effective in inhibiting the replication of ZIKV.
The Contours of Positive Human Health

The primary objectives of this article are (a) to put forth an explicit operational formulation of positive human health that goes beyond prevailing "absence of illness" criteria; (b) to clarify that positive human health does not derive from extant medical considerations, which are not about wellness, but necessarily require a base in philosophical accounts of the "goods" in life; (c) to provoke a change of emphasis from strong tendencies to construe human health as exclusively about the mind or the body toward an integrated and positive spiral of mind-body influences; (d) to delineate possible physiological substrates of human flourishing and offer future directions for understanding the biology of positive health; and (e) to discuss implications of positive health for diverse scientific agendas (e.g., stress, class and health, work and family life) and for practice in health fields (e.g., training, health examinations, psychotherapy, and wellness intervention programs).
"Sub is a weird drug:" A web-based study of lay attitudes about use of buprenorphine to self-treat opioid withdrawal symptoms.

BACKGROUND Illicit use of buprenorphine has increased in the U.S., but our understanding of its use remains limited. This study aims to explore Web-forum discussions about the use of buprenorphine to self-treat opioid withdrawal symptoms. METHODS PREDOSE, a novel Semantic Web platform, was used to extract relevant posts from a Web-forum that allows free discussions on illicit drugs. First, we extract information about the total number of buprenorphine-related posts per year between 2005 and 2013. Second, PREDOSE was used to identify all posts that potentially contained discussions about buprenorphine and opioid withdrawal. A total number of 1,217 posts that contained these terms were extracted and entered into NVivo data base. A random sample of 404 (33%) posts was selected and content analyzed. RESULTS Buprenorphine-related posts increased over time, peaking in 2011. The posts were about equally divided between those that expressed positive and negative views about the effectiveness of buprenorphine in relieving withdrawal symptoms. Web-forum participants emphasized that buprenorphine's effectiveness may become compromised because of the "size of a person habit," and/or when users repeatedly switch back and forth between buprenorphine and other illicit opioids. Most posts reported use of significantly lower amounts of buprenorphine (≤2 mg) than doses used in standard treatment. Concomitant use of other psychoactive substances was also commonly reported, which may present significant health risks. CONCLUSIONS Our findings highlight the usefulness of Web-based data in drug abuse research and add new information about lay beliefs about buprenorphine that may help inform prevention and policy measures.
Locally-Adaptive Texture Compression

Current schemes for texture compression fail to exploit spatial coherence in an adaptive manner due to the strict efﬁciency constraints imposed by GPU-based, fragment-level decompression. In this paper we present a texture compression framework for quasi-lossless, locally-adaptive compression of graphics data. Key elements include a Hilbert scan to maximize spatial coherence, efﬁcient encoding of homogeneous image regions through arbitrarily-sized texel runs, a cumulative run-length encoding supporting fast random-access, and a compression algorithm suitable for ﬁxed-rate and variable-rate encoding. Our scheme can be easily integrated into the rasterization pipeline of current programmable graphics hardware allowing real-time GPU decompression. We show that our scheme clearly outperforms competing approaches such as S3TC DXT1 on a large class of images with some degree of spatial coherence. Unlike other proprietary formats, our scheme is suitable for compression of any graphics data including color maps, shadow maps and relief maps. We have observed compression rates of up to 12:1, with minimal or no loss in visual quality and a small impact on rendering time.
Modelling of highly birefringent dispersion compensating circular Photonic Crystal Fiber

This paper represents a highly birefringence circular-lattice Photonic Crystal Fiber (PCF) which compensates polarization and chromatic dispersion covering the E to U communication bands (1310-1640 nm). The finite element method (FEM) with perfectly matched layers is applied to investigate the guiding properties of the proposed PCF. From simulation, it is observed that the proposed PCF has dispersion coefficient about -220.9032 to -792.7265 (ps/nm-km) for E to U band. Particularly at the wavelength of 1550 nm the value of dispersion coefficient is found to be -678.1918 (ps/nm-km) and nonlinear coefficient is 56.41 (W-1Km-1). Besides that at that particular wavelength (1550 nm), the proposed PCF offers high birefringence which is about 0.0108 with the confinement loss of 0.0542 dB/m.
AB-Chord: An Improved Chord Based on Ant Colony Optimizationand Bi-Directional Lookup Routing

Chord is a popular and successful topology for P2P data sharing. However, the conventional chord has an obvious drawback -- it fails to consider the physical topology of the P2P network for designing the lookup solution, which may bring tremendous delay to network routing. In order to address the drawback and further speeds up searching for local resources, we propose an improved chord based on the Ant Colony Optimization Algorithm and Bi-directional lookup routing method in this paper. We first apply the Ant Colony Optimization Algorithm for building the chord ring to match the topology between the overlay network and physical network. We then develop a bi-directional lookup routing mechanism to further speed up searching for local resources. Simulation results show that our improved chord scheme is significantly more efficient than the conventional chord method.