Miracle-dz/UniFAR-FTUs huggingface dataset:
Parental Bonding in Adolescents With and Without Chronic Pain

Objective Parental responses influence children's pain; however, the specific role of parental bonding in pediatric pain has not been examined. Depressive symptomology is frequently reported in children with chronic pain (CP) and may play a role in the relationship between parental bonding and pain. This study examined the connections between maternal/paternal bonding (perceived care and control) and symptoms of pain and depression in adolescents with CP and in healthy adolescents. Method Participants included 116 adolescents (aged 12-17) with CP (n = 55) and without (n = 61). Adolescents completed the Parental Bonding Instrument separately for their mother and father, as well as measures of depression and pain. Results Significant associations between parental bonding and adolescent pain and depression emerged in the pain group, but not in the healthy group. There were no differences in the impact of maternal versus paternal bonding on adolescent pain and depression. Mediation analyses revealed adolescent depression was a mediator of the relationship between maternal care and adolescent pain, and paternal control and adolescent pain in the group with CP. Conclusions This study highlights the importance of considering parental bonding and adolescent depression in pediatric CP, suggesting that high paternal control and low maternal care contribute to increased pain in adolescents through heightened adolescent depressive symptoms. The findings emphasize the need for family-based treatment for CP that addresses parent behaviors and adolescent mental health.
Ecological risk assessment for aquatic invertebrate communities exposed to imidacloprid as a result of labeled agricultural and nonagricultural uses in the United States

A probabilistic ecological risk assessment (ERA) was conducted to determine the potential effects of acute and chronic exposure of aquatic invertebrate communities to imidacloprid arising from labeled agricultural and nonagricultural uses in the United States. Aquatic exposure estimates were derived using a higher‐tier refined modeling approach that accounts for realistic variability in environmental and agronomic factors. Toxicity was assessed using refined acute and chronic community‐level effect metrics for aquatic invertebrates (i.e., species or taxon sensitivity distributions) developed using the best available data. Acute and chronic probabilistic risk estimates were derived by integrating the exposure distributions for different use patterns with the applicable species or taxon sensitivity distributions to generate risk curves, which plot cumulative probability of exceedance versus the magnitude of effect. Overall, the results of this assessment indicated that the aquatic invertebrate community is unlikely to be adversely affected by acute or chronic exposure to imidacloprid resulting from currently registered uses of imidacloprid in the United States. Environ Toxicol Chem 2017;36:1375–1388. © 2016 SETAC
Building Coordinate System of Sensor Nodes Using Self-configurable Grid-based Approach

Establishing relative coordinate system is essential for many applications of sensor networks. This paper proposes a computation scalable scheme for establishing relative coordinate system of sensor networks using distance measurements between sensors. A distributed selection algorithm is proposed to select a small number of nodes from all sensors to serve as virtual grid point and establish the grid relative coordinate system. The grid coordinate system forms the backbone of localization for static and mobile nodes, whereby the non-grid nodes can compute their positions via message exchange with their neighboring grid nodes. This paper shows by both mathematical analysis and simulations that the localization error of the scalable grid approach is upper bounded by half the grid width (i.e., the length of two adjacent grid points). The results also indicate that the precision of grid coordinate system can be adaptively adjusted by the grid width and the density of grid nodes to meet target applications. For those non-grid nodes, the results show that the localization precision of non-grid nodes would be bounded by one grid-cell error.
Chemical Vapour Deposition An Integrated Engineering Design For Advanced Materials

Thank you very much for reading chemical vapour deposition an integrated engineering design for advanced materials. Maybe you have knowledge that, people have search hundreds times for their chosen books like this chemical vapour deposition an integrated engineering design for advanced materials, but end up in harmful downloads. Rather than enjoying a good book with a cup of coffee in the afternoon, instead they are facing with some harmful virus inside their laptop.
Beauty Is in the Eye of the Beholder

in this monthly column, ric peri of the AeA's Washington, d.c. office, informs members of the latest regulatory updates. Beauty is in the Eye of the Beholder W hile this proverb dates back to the third century B.C., it is most recently cited by Benja-min Franklin in his 1741 Poor Richard's Almanac. In it he wrote, " Beauty, like supreme domination, is but supported by opinion. " In Washington, one cannot attend a meeting without someone talking about " raising the bar. " The question that must be asked is: " Why? " Is it because safety has been compromised, or is it that the industry norm is so far above the bar, and the regulations lag behind? There are ongoing attempts to " raise the bar " for aircraft technicians, and the question has to be asked, Why? Is the aircraft technician " un-safe? " No, of course not. The regulations assure safety and airworthiness have not been compromised. It just feels good, so it must be right to raise the bar. 14 CFR Part 65 is quite adequate to assure that technicians only accomplish those tasks that they are authorized to perform, with the proper equipment and the appropriate data. Part 147 contains a curriculum that is acceptable as a minimum standard for an apprentice technician. But, employers want more. Employers want apprentices with more advanced skills, better training and exposure to more advanced equipment. Employers want the bar raised. Now the question to be asked is: Are we " raising the bar " as a matter of safety, or is it to improve productivity? Advancing the aircraft maintenance profession requires raising the bar. Each new generation should be better educated , better trained and capable of higher productivity. Simply because the minimum standard is regulated by the Federal Aviation Administration doesn't support the argument that the FAA is the only entity capable of raising the bar. Why is it that aircraft maintenance should be different than non-aviation trades? It is our industry, let us raise the bar. The FAA has a role in assuring the highest standard of aviation safety. But its role is specific: regulatory oversight of aviation law. They provide for a minimum level of safety through the development , maintenance and enforcement of aviation regulations. With few exceptions , the FAA does this well. But what about bringing the aviation industry to the next …
Gradient Algorithms for Complex Non-Gaussian Independent Component/Vector Extraction, Question of Convergence

We revise the problem of extracting one independent component from an instantaneous linear mixture of signals. The mixing matrix is parameterized by two vectors: one column of the mixing matrix, and one row of the demixing matrix. The separation is based on the non-Gaussianity of the source of interest, while the remaining background signals are assumed to be Gaussian. Three gradient-based estimation algorithms are derived using the maximum likelihood principle and are compared with the Natural Gradient algorithm for Independent Component Analysis and with One-Unit FastICA based on negentropy maximization. The ideas and algorithms are also generalized to the extraction of a vector component when the extraction proceeds jointly from a set of instantaneous mixtures. Throughout this paper, we address the problem concerning the size of the region of convergence for which the algorithms guarantee the extraction of the desired source. We show that the size is influenced by the signal-to-interference ratio on the input channels. Simulations comparing several algorithms confirm this observation. They show a different size of the region of convergence under a scenario in which the source of interest is dominant or weak. Here, our proposed modifications of the gradient methods, taking into account the dominance/weakness of the source, show improved global convergence.
Not all that glitters is gold—Electron microscopy study on uptake of gold nanoparticles in Daphnia magna and related artifacts

Increasing use of engineered nanoparticles has led to extensive research into their potential hazards to the environment and human health. Cellular uptake from the gut is sparsely investigated, and microscopy techniques applied for uptake studies can result in misinterpretations. Various microscopy techniques were used to investigate internalization of 10‐nm gold nanoparticles in Daphnia magna gut lumen and gut epithelial cells following 24‐h exposure and outline potential artifacts (i.e., high‐contrast precipitates from sample preparation related to these techniques). Light sheet microscopy confirmed accumulation of gold nanoparticles in the gut lumen. Scanning transmission electron microscopy and elemental analysis revealed gold nanoparticles attached to the microvilli of gut cells. Interestingly, the peritrophic membrane appeared to act as a semipermeable barrier between the lumen and the gut epithelium, permitting only single particles through. Structures resembling nanoparticles were also observed inside gut cells. Elemental analysis could not verify these to be gold, and they were likely artifacts from the preparation, such as osmium and iron. Importantly, gold nanoparticles were found inside holocrine cells with disrupted membranes. Thus, false‐positive observations of nanoparticle internalization may result from either preparation artifacts or mistaking disrupted cells for intact cells. These findings emphasize the importance of cell integrity and combining elemental analysis with the localization of internalized nanoparticles using transmission electron microscopy. Environ Toxicol Chem 2017;36:1503–1509. © 2016 SETAC
Using social norms theory for health promotion in low-income countries

Summary Social norms can greatly influence people’s health-related choices and behaviours. In the last few years, scholars and practitioners working in low- and mid-income countries (LMIC) have increasingly been trying to harness the influence of social norms to improve people’s health globally. However, the literature informing social norm interventions in LMIC lacks a framework to understand how norms interact with other factors that sustain harmful practices and behaviours. This gap has led to short-sighted interventions that target social norms exclusively without a wider awareness of how other institutional, material, individual and social factors affect the harmful practice. Emphasizing norms to the exclusion of other factors might ultimately discredit norms-based strategies, not because they are flawed but because they alone are not sufficient to shift behaviour. In this paper, we share a framework (already adopted by some practitioners) that locates norm-based strategies within the wider array of factors that must be considered when designing prevention programmes in LMIC.
Chaos-based communications at high bit rates using commercial fibre-optic links

Chaotic signals have been proposed as broadband information carriers with the potential of providing a high level of robustness and privacy in data transmission. Laboratory demonstrations of chaos-based optical communications have already shown the potential of this technology, but a field experiment using commercial optical networks has not been undertaken so far. Here we demonstrate high-speed long-distance communication based on chaos synchronization over a commercial fibre-optic channel. An optical carrier wave generated by a chaotic laser is used to encode a message for transmission over 120 km of optical fibre in the metropolitan area network of Athens, Greece. The message is decoded using an appropriate second laser which, by synchronizing with the chaotic carrier, allows for the separation of the carrier and the message. Transmission rates in the gigabit per second range are achieved, with corresponding bit-error rates below 10-7. The system uses matched pairs of semiconductor lasers as chaotic emitters and receivers, and off-the-shelf fibre-optic telecommunication components. Our results show that information can be transmitted at high bit rates using deterministic chaos in a manner that is robust to perturbations and channel disturbances unavoidable under real-world conditions.
Using WordNet into UKB in a Question Answering System for Basque

This paper presents the use of semantic information at chunk level in a Question Answering system called Ihardetsi. The semantic information has been added through a tool called UKB. For this experiment, UKB uses the Basque WordNet to compute the similarity between the chunks. We use this added information to help Ihardetsi to choose the correct answer among all the extracted candidates. Along with the description of the system, we outline its performance presenting an experiment and the obtained results.
Evaluation of the Effects of Physical Activity, Cardiorespiratory Condition, and Neuromuscular Fitness on Direct Healthcare Costs and Sickness-Related Absence Among Nursing Personnel With Recurrent Nonspecific Low Back Pain

Study Design. A cross-sectional study, part of a randomized controlled trial. Objective. To evaluate the association of physical activity, cardiorespiratory fitness, and neuromuscular fitness with direct healthcare costs and sickness-related absence among nursing personnel with nonspecific low back pain. Summary of Background Data. Low back pain creates a huge economic burden due to increased sick leave and use of healthcare services. Methods. Female nursing personnel with nonspecific low back pain were included (n = 219). Physical activity was assessed with accelerometry and a questionnaire. In addition, measurements of cardiorespiratory and muscular fitness were conducted. Direct costs and sickness-related absence for a 6-month period were collected retrospectively by questionnaire. Health care utilization and absence from work were analyzed with a general linear model. Results. The mean total costs were 80.5% lower among women who met physical activity recommendations than inactive women. Those with a higher mean daily intensity level of 10-minute activity sessions showed lower total costs than women in the lowest tertile (middle: 64.0% of the lowest; highest: 54.3% of the lowest). Women with good cardiorespiratory fitness (the highest tertile) as measured with the 6-minute-walk test (based on walking distance) had 77.0% lower total costs when compared with the lowest tertile. Women in the highest third for the modified push-up test had 84.0% lower total costs than those with the poorest results (the bottom tertile). Conclusion. High cardiorespiratory and muscular fitness and meeting physical activity recommendations for aerobic and muscular fitness were strongly associated with lower total costs among nursing personnel with pain-related disorders of recurrent nonspecific low back pain. Actions to increase physical activity and muscle conditioning may significantly save on healthcare costs and decrease sick-leave costs due to low back pain. Level of Evidence: 3
Concept Similarity under the Agent's Preferences for the Description Logic FL0 with Unfoldable TBox

Concept similarity refers to human judgment of a degree to which a pair of concepts is similar. Computational techniques attempting to imitate such judgment are called concept similarity measures. In Description Logics (DLs), we could regard them as a generalization of the classical reasoning problem of equivalence. That is, any two concepts are equivalent if and only if their similarity degree is one. When two concepts are not equivalent, the level of similarity varies depending not only on the objective factors (e.g. the structure of concept descriptions) but also on the subjective factors (i.e. the agent’s preferences). The recently introduced notion called preference profile identified a collection of preferential elements in which any developments for concept similarity measure should consider. In this paper, we briefly review approaches of identifying the subsumption degree between FL0 concept descriptions and exemplify how one can adopt the viewpoint of preference profile toward the development of concept similarity measure under the agent’s preferences in FL0. Finally, we investigate several properties of the developed measure and discuss future directions.
HDAC Inhibitors Disrupt Programmed Resistance to Apoptosis During Drosophila Development

We have previously shown that the ability to respond to apoptotic triggers is regulated during Drosophila development, effectively dividing the fly life cycle into stages that are either sensitive or resistant to apoptosis. Here, we show that the developmentally programmed resistance to apoptosis involves transcriptional repression of critical proapoptotic genes by histone deacetylases (HDACs). Administration of HDAC inhibitors (HDACi), like trichostatin A or suberoylanilide hydroxamic acid, increases expression of proapoptotic genes and is sufficient to sensitize otherwise resistant stages. Conversely, reducing levels of proapoptotic genes confers resistance to otherwise sensitive stages. Given that resistance to apoptosis is a hallmark of cancer cells, and that HDACi have been recently added to the repertoire of FDA-approved agents for cancer therapy, our results provide new insights for how HDACi help kill malignant cells and also raise concerns for their potential unintended effects on healthy cells.
Performance Analysis of QoS-Differentiated Pricing in Cloud Computing: An Analytical Approach

A fundamental goal in the design of IaaS service is to enable both user-friendly and cost-effective service access, while attaining high resource efficiency for revenue maximization. QoS differentiation is an important lens to achieve this design goal. In this paper, we propose the first analytical QoS-differentiated resource management and pricing architecture in the cloud computing context; here, a cloud service provider (CSP) offers a portfolio of SLAs. In order to maximize the CSP's revenue, we address two technical questions: (1) how to set the SLA prices so as to direct users to the SLAs best fitting their needs, and, (2) determining how many servers should be assigned to each SLA, and which users and how many of their jobs are admitted to be served. We propose optimal schemes to jointly determine SLA-based prices and perform capacity planning in polynomial time. Our pricing model retains high usability at the customer's end. Compared with standard usage-based pricing schemes, numerical results show that the proposed scheme can improve the revenue by up to a five-fold increase.
Paper No P26: Design of Structured Surfaces and Anisotropic Materials for Display and Photonic Applications

In this article, we show how inorganic and organic structured surfaces, anisotropic materials can be prepared and used for display and photonic applications. The presented results demonstrate that the design of anisotropic materials, the electrochemical formation of structured surfaces, and their combination can provide desirable variations in the anisotropic material properties; in the parameters of structured surfaces for improved satisfaction of the requirements for using them as the components for display and photonic applications.
A rare case of unprovoked venous thromboembolism manifestation in a young patient with antithrombin Type IIB deficiency combined with inferior vena cava anomaly from Lithuania

Summary Hereditary antithrombin (AT) deficiency is an autosomal-dominant disorder predisposing to venous and arterial thrombosis. Homozygosity resulting in severe AT deficiency is not compatible with life, apart from homozygous mutations affecting the heparin-binding site representing the most severe thrombophilia. Patients and methods: A 12-year-old previously healthy boy of Romani origin presented with a swollen, painful left leg and fever. Imaging revealed signs of inferior vena cava (IVC) thrombosis, the presence of interrupted intrahepatic IVC with azygos continuation and bilateral iliofemoral thrombosis with enlargement of the azygous and hemiazygos venous system. In addition, right pleural effusion and signs of bilateral renal pericortical cysts, possibly caused by retroperitoneal lymphangiectasia, were disclosed. Thrombophilia screening involving protein C, Protein S, Antithrombin (chromogenic assays based on the inhibition of FIIa and FXa, antigen concentration), APC resistance, prothrombin mutation and Lupus anticoagulants was performed using standard laboratory methods. Genetic analysis of the SERPINC1 gene was done by direct sequencing. Results: Thrombophilia screening showed isolated decreased AT activity at 21% (RR 80–120%). AT levels were retested and remained decreased (33–36%) on two consecutive occasions. SERPINC1 gene analysis revealed a previously described homozygous mutation (Budapest III) causing type IIB deficiency (c.391C>T; p.Leu131Phe). A family study confirmed the same mutation in both parents and three siblings. The patient improved significantly following warfarin therapy and over the past 2.5 years did not experience new thromboembolism. Conclusions: This case represents a rare combination of two risk factors provoking manifestation of spontaneous venous thromboembolism at a young age requiring permanent anticoagulant therapy.
Non-NMDA and NMDA receptors in the synaptic pathway between area postrema and nucleus tractus solitarius.

Area postrema (AP) modulates cardiovascular function through excitatory projections to neurons in nucleus tractus solitarius (NTS), which also process primary sensory (including cardiovascular-related) input via the solitary tract (TS). The neurotransmitter(s) and their receptors in the AP-NTS pathway have not been fully characterized. We used whole cell recordings in voltage- and current-clamp modes in the rat brain stem slice to examine the role of ionotropic glutamatergic receptors and α2-adrenergic receptors in the pathway from AP to NTS neurons receiving visceral afferent information via the TS. In neurons voltage clamped at potentials from -100 to +80 mV, AP stimulation (0.2 Hz) evoked excitatory postsynaptic currents having a fast component blocked by the non- N-methyl-d-aspartate (NMDA) receptor antagonist 1,2,3,4-tetrahydro-6-nitro-2,3-dioxobenzoquinoxaline-7-sulfonamide (NBQX; 3 μM, n = 7) and a slow component blocked by the NMDA receptor antagonistdl-2-amino-5-phosphonovaleric acid (APV; 50 μM, n = 8). Although NBQX (3 μM, n = 14) abolished AP-evoked action potentials, APV (50 μM, n = 9 or 500 μM, n = 6) or yohimbine, (200 nM, n = 5 or 2 μM, n = 10) did not. Thus, although AP stimulation activates both non-NMDA and NMDA receptors on NTS neurons receiving TS input, only non-NMDA receptors are required for synaptic transmission.
Efficient Pitch Estimation on Natural Opera-Singing by a Spectral Correlation based Strategy

We present in this work a study for robust pitch estimation on signals presenting wide-range pitch content, as is the case of opera singing. Aiming to perform automatic features extraction for the further development of parametric opera singing synthesis technology we evaluate four state-of-the-art pitch estimators, reporting in particular technical details of one introduced in previous work, based in a technique called Spectral Amplitude Autocorrelation (SAC). The results issued from subjective and objetive evaluations show clear performance trends, denoting robust estimation performance for SAC without observing significant sensitivity to the pitch height.