Miracle-dz/UniFAR-FTUs huggingface dataset:
Marketing Quality of Texts Posted on the Websites of Rural Tourism Facilities in Poland

Summary Subject and purpose of work: The subject of the research were texts published on the websites of rural tourism facilities in Poland, and the purpose of the work was to assess their marketing quality. Materials and methods: The evaluation of the marketing quality of the texts was carried out using the web application Audyt Hekko (Blink) on a collection of 842 websites of rural tourism facilities. Results: Texts with a low (poor) marketing utility (as assessed by the testing algorithm) were found on 362 websites, which constituted approximately 44% of the set. Approximately 46.5% of the websites contained texts whose marketing utility was sufficient. Texts posted on 10% of the analysed websites were rated as useful for marketing. Conclusions: The semantic evaluation of the texts published on most rural tourism facilities websites has shown that they have been written in the language of benefits, with the use of phrases that may arouse interest and curiosity. At the same time, however, they required optimization and a greater marketing orientation.
Selected Proteins of the Complement System as Morphological Indicators of Early Myocardial Infarction

Background: Morphological diagnosis of advanced myocardial infarction is not difficult; however its early phases usually remain indistinguishable in a macroscopic examination, and are often invisible under the microscope or hard to interpret unequivocally. The aim of this paper is to determine the usefulness of immunohistochemical staining to detect C1q, C9 and C5b-9, in the morphological diagnosis of an early myocardial infarction. Data and methodology: The experimental group consisted of tissue samples with suspected myocardial infarction unconfirmed in a routine morphological diagnosis (n=22). The control group consisted of myocardium samples without salient pathologies (n=10). Immunohistochemical reactions were conducted using a detection system based on enzymatic peroxidase reaction. The IHC reaction assessment was conducted based on halfquantitative Immunoreactive Score scale. Results: Morphological analysis of preparations based on haematoxylin and eosin staining in the experimental group did not show important changes that would denote myocardial infarction. The immunohistochemical reaction for C1q and C9 was intense, whereas in case of C5b-9 it was weak in all examined myocardium samples of the experimental group. In the control group no positive immunohistochemical reaction was observed. Conclusion: The results can indicate that immunohistochemical reactions to detect C1q and C9 can be a morphological indicator of early myocardial infarction. Reactions to detect C5b-9 are not specific to early myocardial infarction.
Implicit Emotion Communication

Today, ubiquitous digital communication systems do not have an intuitive, natural way of communicating emotion, which, in turn, affects the degree to which humans can emotionally connect and interact with one another. To address this problem, a more natural, intuitive, and implicit emotion communication system was designed and created that employs asymmetry-based EEG emotion classification for detecting the emotional state of the sender and haptic feedback (in the form of tactile gestures) for displaying emotions for a receiver. Emotions are modeled in terms of valence (positive/negative emotions) and arousal (intensity of the emotion). Performance analysis shows that the proposed EEG subject-dependent emotion classification model with Free Asymmetry features allows for more flexible feature-generation schemes than other existing algorithms and attains an average accuracy of 92.5% for valence and 96.5% for arousal, outperforming previous-generation schemes in high feature space. As for the haptic feedback, a tactile gesture authoring tool and a haptic jacket were developed to design tactile gestures that can intensify emotional reactions in terms of valence and arousal. Experimental study demonstrated that subject-independent emotion transmission through tactile gestures is effective for the arousal dimension of an emotion but is less effective for valence. Consistency in subject-dependent responses for both valence and arousal suggests that personalized tactile gestures would be more effective.
Strategies to Manage Risk and their Role in Impacting Economic Performance among Farm Households

Data from the 2015 ARMS and a multinomial probit regression model were used in an attempt to discern the impact of socio-economic factors on the likelihood of a farm household falling in a favorable income-wealth category delineated by above-median income and wealth levels. A primary determinant considered was the number of risk management strategies utilized by the farm household. Findings indicate that farmers who layer up the adoption of risk management strategies are most likely to secure an economic performance status characterized by ‘low-income, high-wealth’. Aging farm operators and those with college education and who operate larger sized farms are found more likely to be in the top economic performance category of ‘high-income, high-wealth’.
Unifying recommendation and active learning for human-algorithm interactions

The enormous scale of the available information and products on the Internet has necessitated the development of algorithms that intermediate between options and human users. These algorithms do not select information at random, but attempt to provide the user with relevant information. In doing so, the algorithms may incur potential negative consequences related to, for example, “filter bubbles. ” Building from existing algorithms, we introduce a parametrized model that unifies and interpolates between recommending relevant information and active learning. In a concept learning paradigm, we illustrate the trade-offs of optimizing prediction and recommendation, show that there is a broad parameter region of stable performance that optimizes for both, identify a specific regime that is most robust to human variability, and identify the cause of this optimized performance. We conclude by discussing implications for the cognitive science of concept learning and the practice of machine learning in the real world.
Trade Agreements and Transnational Corporations Presence in the Developing Asia

This paper investigates the effect of trade agreements on the transnational corporation presence in the developing Asia. This hypothesis is tested on the sample of 9 Asian developing countries for twenty-one years’ time. Evidence is found that the Trade agreements had a significant impact on the FDI received by these Asian countries. Along with trade agreements other conventional FDI location pull factors also play a significant role in the attraction of FDI to the specific region. Through fixed effects panel estimation method, it is found that countries with large market size, educated labour and the low trade barriers are important aspects, which MNC’s consider while making investment in this region.
LIM Kinase 1 Modulates Opsonized Zymosan-triggered Activation of Macrophage-like U937 Cells

We have previously reported that cofilin, an actin-binding protein, plays an important role in phagocyte functions, such as respiratory burst, phagocytosis, and chemotaxis. On the other hand, it was recently found that LIM motif-containing kinase (LIMK) phosphorylates cofilin. In this work, we investigated the roles of LIMK in activated phagocytes. The results of immunostaining showed that in dormant phagocytes the endogenous LIMK1 was diffusely distributed in the cytosol of macrophage-like U937 cells, and when activated by opsonized zymosan (OZ), it was translocated to plasma membranes. Green fluorescence protein (GFP)-conjugated LIMK was expressed in the phagocytes, and the GFP-positive cells were isolated by a fluorescence-activated cell sorter. The isolated wild-type LIMK-overexpressing cells produced superoxide at a rate that was 3.2-fold higher than that of only GFP-expressing control cells, whereas the respiratory burst of dominant negative LIMK1(D460A)-expressing cells decreased to 31% of that of the control cells. Phagocytic activity monitored by using Texas Red-labeled OZ was also decreased in the D460A-expressing cells. By immunoblotting using a specific anti-phosphorylated cofilin antibody, it was revealed that in the OZ-activated wild-type LIMK1-GFP-expressing cells, the phosphorylated cofilin increased by 2.3-fold, and that in the OZ-activated D460A-GFP-expressing cells, the phosphorylated cofilin decreased to 47% of that of only GFP-expressing cells (mock control). Furthermore, in the wild-type LIMK1-expressing cells, OZ-evoked increase in filamentous actin was markedly enhanced, whereas in the dominant negative LIMK1-expressing cells, the total level of F-actin was strongly suppressed. These results suggest that LIMK1 regulates the functions of phagocytes through phosphorylation of cofilin and enhances the formation of filamentous actin.
Supervised Hashing with End-to-End Binary Deep Neural Network

Image hashing is a popular technique applied to large scale content-based visual retrieval due to its compact and efficient binary codes. Our work proposes a new end-to-end deep network architecture for supervised hashing which directly learns binary codes from input images and maintains good properties over binary codes such as similarity preservation, independence, and balancing. Furthermore, we also propose a new learning scheme that can cope with the binary constrained loss function. The proposed algorithm not only is scalable for learning over large-scale datasets but also outperforms state-of-the-art supervised hashing methods, which are illustrated throughout extensive experiments from various image retrieval benchmarks.
Mechanism of therapeutic action of abiogenic Li+ and Ga3+ ions: insights from theoretical studies

Lithium and gallium (Li+ and Ga3+) exhibit no known biological functions and are categorized as abiogenic ions. However, they are used in medicine (in the form of soluble salts) as a first-line drugs for treatment of bipolar disorder (Li+) or cancer-related hypercalcemia (Ga3+) as well as a drug with antiproliferative action in clinical trials (Ga3+). Even though their therapeutic effects are well known, there are many unanswered questions concerning their mechanism of action. The main hypotheses posit competition between Li+ and the native Mg2+, and between Ga3+ and the cognate Fe3+ ions for binding to some metalloenzymes involved in cell signaling and cell proliferation, respectively. The conducted theoretical research explains some of the most accepted hypotheses about the therapeutic action of the two alien cations. The factors governing the competition between biogenic and abiogenic cations in protein binding sites are also revealed. The theoretical results are in line with experimental data.
PROOF COPY ONLY Anomalous fading parameters and activation energies of feldspars

Anomalous fading parameters and activation energies are reported for a variety of feldspars and K-feldspars separated from sediments. While some interesting patterns emerge, prediction of the fading parameter from a measurement of the activation energy would appear to be unwise. There was a tendency for the activation energy to increase from 0.04 to 0.2 eV as the K content increases from 0 to 15 %.
Insight into Pulmonary Gas Trapping as an Index of Airway Responses in Small Laboratory Animals

The majority of methods for measuring airway mechanics or pulmonary function in small laboratory animals are labor intensive, require specialized equipment and training, and have a low throughput. Hence, there is a need for a more rapid, simpler, userfriendly approach for assessing airway responses in rodent models of human lung diseases. One such method is pulmonary gas trapping or the excised lung gas volume (ELGV) measurement [1,2], a wellrecognized technique for assessing airway mechanics in small laboratory animals [3]. Thus, a brief overview of the history of pulmonary gas trapping or hyperinflation will be discussed examining history of both qualitative and quantitative approaches and use in rodent models of human lung diseases.
Progress in and deterrents to orthotopic liver transplantation, with special reference to survival, resistance to hyperacute rejection, and biliary duct reconstruction.

There is almost no aspect of clinical organ transplantation into which Dave Hume did not breathe life. Liver transplantation was no exception. It will surprise no one that his contributions were important and concisely stated, although never published. He gave his observations to one of us (T.E.S.) as personal communications throughout the years and granted permission for their use in a book published 5 years ago.1 They should be listed briefly. Hume performed one of the earliest auxiliary hepatic transplantations, to the splenic fossa of a recipient whose abdomen could not accommodate the extra organ plus the host liver. Undaunted, he proceeded to remove the total native liver. In another trial, this time with orthotopic transplantation, Hume described hyperacute rejection, which if it was a valid diagnosis was the first and only documented example of this complication destroying a liver homograft. Finally, one of Hume’s recipients who had a hepatoma plus cirrhosis lived for about a year postoperatively after liver replacement, eventually dying with widespread metastases similar to those we have recorded after hepatic transplantation for the indication of malignancy.1 There is no point in saying more about these experiences of Hume, since, important as they were, they were really peripheral to his main interests. Instead, I would like to discuss three aspects of orthotopic liver transplantation that might introduce either new data or new ideas. These concern our survival statistics, hyperacute rejection in livers, and the problem of biliary duct reconstruction.
A dual planar reflectarray with synthesized phase and amplitude distribution

A quasi-planar reflector arrangement for generating an arbitrary phase and amplitude distribution in the antenna aperture and thus a wide range of far field patterns is presented. A parallel pair of reflectarrays is used. One is implemented as a standard reflectarray using rectangular patches on a microwave substrate with metallized backside. The other reflectarray is provided with a polarizing grid, which acts as a ground plane for one polarization and is transparent for the orthogonal polarization. An offset rectangular feed horn is embedded in the lower reflectarray to illuminate the upper reflector. A design procedure for a linear polarized antenna with a sector beam in the azimuth and a narrow beam width in the elevation is presented and is verified with measurement results.
Cellular Dynamics of Mouse Trophoblast Stem Cells: Identification of a Persistent Stem Cell Type1

ABSTRACT Mouse trophoblast stem cells (TSCs) proliferate indefinitely in vitro, despite their highly heterogeneous nature. In this study, we sought to characterize TSC colony types by using methods based on cell biology and biochemistry for a better understanding of how TSCs are maintained over multiple passages. Colonies of TSCs could be classified into four major types: type 1 is compact and dome-shaped, type 4 is flattened but with a large multilayered cell cluster, and types 2 and 3 are their intermediates. A time-lapse analysis indicated that type 1 colonies predominantly appeared after passaging, and a single type 1 colony gave rise to all other types. These colony transitions were irreversible, but at least some type 1 colonies persisted throughout culture. The typical cells comprising type 1 colonies were small and highly motile, and they aggregated together to form primary colonies. A hierarchical clustering based on global gene expression profiles suggested that a TSC line containing more type 1 colony cells was similar to in vivo extraembryonic tissues. Among the known TSC genes examined, Elf5 showed a differential expression pattern according to colony type, indicating that this gene might be a reliable marker of undifferentiated TSCs. When aggregated with fertilized embryos, cells from types 1 and 2, but not from type 4, distributed to the polar trophectoderm in blastocysts. These findings indicate that cells typically found in type 1 colonies can persist indefinitely as stem cells and are responsible for the maintenance of TSC lines. They may provide key information for future improvements in the quality of TSC lines.
Two Cases of Infections Due to Multidrug-Resistant Bacteroides fragilis Group Strains

ABSTRACT Bacteroides fragilis group strains are still considered susceptible to most antimicrobial agents used for the treatment of infections caused by anaerobic organisms. We describe two cases of infections due to isolates simultaneously resistant to clindamycin, tetracycline, cefoxitin, piperacillin-tazobactam, and imipenem and, in one of the two cases, to metronidazole. Such infections, although still rare, do exist and tend to complicate treatment.
Hypothalamic modulation of the arterial chemoreceptor reflex in the anaesthetized cat: role of the nucleus tractus solitarii.

1. There is evidence in the literature of a mutual facilitatory interaction between the arterial chemoreceptor reflex and the alerting stage of the defence reaction, particularly in relation to the patterning of cardiorespiratory activity. The present study has been designed to test the hypothesis that a portion of this interaction involves synaptic interactions within the nucleus tractus solitarii (NTS). 2. The study has involved an analysis of the effective interactions between the stimulation of the arterial chemoreceptors and the hypothalamic defence area (HDA) on the activity of NTS neurones recorded in anaesthetized, paralysed and artificially ventilated cats. 3. A group of eighteen NTS neurones was classified as chemosensitive, on the basis of displaying EPSPs on sinus nerve stimulation (SN) and their failure to show an excitatory response to baroreceptor stimulation. Thirteen of these neurones displayed pronounced excitatory responses to chemoreceptor stimulation. In sixteen of these neurones HDA stimulation elicited an EPSP; in four of these sixteen neurones this early EPSP was followed by an IPSP. In the remaining two (of 18) neurones HDA stimulation provoked no obvious synaptic response but facilitated the efficacy of both chemoreceptor inputs and SN stimulation. 4. Neurones shown to receive convergent inputs from the arterial chemoreceptors (and SN stimulation) and HDA, often displayed excitatory responses to stimulation of other peripheral inputs. Vagally evoked EPSPs were observed in nine neurones, SLN‐evoked responses in seven neurones and aortic nerve‐evoked EPSPs in three neurones. 5. The organization of these synaptic interactions is discussed and these data are used to explain the pattern of interaction between chemoreceptor, baroreceptor and HDA inputs within the NTS. Conclusions are drawn regarding the functional role of different classes of NTS neurone, based on the findings in this and the accompanying two papers.
Interaction of the Wiskott–Aldrich syndrome protein with sorting nexin 9 is required for CD28 endocytosis and cosignaling in T cells

The Wiskott–Aldrich syndrome protein (WASp) plays a major role in coupling T cell antigen receptor (TCR) stimulation to induction of actin cytoskeletal changes required for T cell activation. Here, we report that WASp inducibly binds the sorting nexin 9 (SNX9) in T cells and that WASp, SNX9, p85, and CD28 colocalize within clathrin-containing endocytic vesicles after TCR/CD28 costimulation. SNX9, implicated in clathrin-mediated endocytosis, binds WASp via its SH3 domain and uses its PX domain to interact with the phosphoinositol 3-kinase regulatory subunit p85 and product, phosphoinositol (3,4,5)P3. The data reveal ligation-induced CD28 endocytosis to be clathrin- and phosphoinositol 3-kinase-dependent and TCR/CD28-evoked CD28 internalization and NFAT activation to be markedly enhanced by SNX9 overexpression, but severely impaired by expression of an SNX9 mutant (SNX9ΔPX) lacking p85-binding capacity. CD28 endocytosis and CD28-evoked actin polymerization also are impaired in WASp-deficient T cells. These findings suggest that SNX9 couples WASp to p85 and CD28 so as to link CD28 engagement to its internalization and to WASp-mediated actin remodeling required for CD28 cosignaling. Thus, the WASp/SNX9/p85/CD28 complex enables a unique interface of endocytic, actin polymerizing, and signal transduction pathways required for CD28-mediated T cell costimulation.
Investigation of fabricated Through Glass Via (TGV) process by inductively coupled plasma reactive ion etching of quartz glass

In this paper, we report the fabrication process of Through Glass Via (TGV) structure and basic design rules for glass based Three-Dimensional Integrated Circuit (3D-IC) packaging as well as a process flow for glass interposer applications. Quartz glass materials have been widely used in many packaging applications for micro electromechanical systems (MEMS), optical devices, and biomedical chips. Our work focuses on a 3D-IC package approach based on the use of thin glass as a substrate material. For through-glass-vias, holes were etched in glass wafers by photolithography and inductively coupled plasma-reactive ion etching (ICP-RIE) technologies and evaluated. The results of fabrication of TGV morphology showed a very good compromise between wafer thickness, TGV shape and via diameter for vertical interposer with 50 μm diameters in 150 μm thin quartz glass wafer still very stable for thin wafer processing without complicated processes.
The kinetics and mechanism of iron (3) exchange between chelates and transferrin. I. The complexes of citrate and nitrilotriacetic acid.

Abstract The rate at which iron(III) is transferred from various chelating agents to the metal-binding sites in human transferrin is a function of the chemical nature of the complexing agent. Although equilibrium concentrations are related to the magnitude of the relative stability constants, the kinetics of transfer appears to be regulated by steric factors. The time required for equimolar concentrations of three typical chelates to half-saturate the sites is nitrilotriacetate, 3 sec; citrate, 8 hours; ethylenediaminetetraacetate, about 4 days. The kinetics of ferric citrate transfer is complicated by the polynuclear behavior of this chelate. At a citrate to iron ratio of 1:1, the rate-limiting step of the metal binding is depolymerization to a low molecular weight, reactive complex. At ratios above 20:1, polymerization is suppressed by the formation of ferric dicitrate, which reacts rapidly with the protein to release the metal via the formation of a reactive ferric citrate complex. A reaction sequence is proposed involving the formation of a ternary complex of chelate-iron-transferrin as an intermediate. Ionic Fe(III) does not appear to be involved in the transfer.
Control-enhanced power-SIMD

: When applications exhibit more complex control ﬂow behaviors, wide single-instruction multiple-data (SIMD) architecture is ineﬃcient, which mainly due to two aspects, vector condition branch and nested loop. To solve this problem, this paper proposes two independent ideas: the data-aware thread-level parallelism (DATLP) and hardware-supported software pipeline scheduling policy (HSSP). They share the same hardware which is the instruction buﬀer queue (IBQ), to improve the eﬃciency by increasing Instruction-Level Parallelism (ILP) and Thread-Level Parallelism (TLP). Compared with the traditional SIMD-architecture, the proposed control-enhanced power SIMD, will get an average performance improvement by 84% for a wide variety of media and 4G wireless communication applications, while the area overhead only increases by 2.97%.