Miracle-dz/UniFAR-FTUs huggingface dataset:
A Developmentally Regulated Splice Variant from the Complexlola Locus Encoding Multiple Different Zinc Finger Domain Proteins Interacts with the Chromosomal Kinase JIL-1*

Using a yeast two-hybrid screen we have identified a novel isoform of the lola locus, Lola zf5, that interacts with the chromosomal kinase JIL-1. We characterized thelola locus and provide evidence that it is a complex locus from which at least 17 different splice variants are likely to be generated. Fifteen of these each have a different zinc finger domain, whereas two are without. This potential for expression of multiple gene products suggests that they serve diverse functional roles in different developmental contexts. By Northern and Western blot analyses we demonstrate that the expression of Lola zf5 is developmentally regulated and that it is restricted to early embryogenesis. Immunocytochemical labeling with a Lola zf5-specific antibody of Drosophila embryos indicates that Lola zf5 is localized to nuclei. Furthermore, by creating double-mutant flies we show that a reduction of Lola protein levels resulting from mutations in the lola locus acts as a dominant modifier of a hypomorphic JIL-1 allele leading to an increase in embryonic viability. Thus, genetic interaction assays provide direct evidence that gene products from the lola locus function within the same pathway as the chromosomal kinase JIL-1.
In/visibility of LGBTQ people in the Arab Spring

LGBTQ use of the internet is a growing area of study. However most studies focus mainly on the US and the UK, and none pays much (if any) attention to the experience of LGBTQ people in countries where it is illegal to be LGBTQ. The events of the Arab Spring, significantly, signal the possibility that change may be possible in these countries, yet there seems to be little material on what LGBTQ people in these countries are actually thinking, doing, etc, and in particular what role the internet may be playing in this. This is a research-in- progress paper introducing a project which sets out to make a contribution on these lines, by making their voices heard.
Performance analysis of aodv for wormhole attack using different mobility models

Mobile Ad-Hoc Network (MANET) is a type of temporary wireless network, in which the nodes are mobile and have dynamic network topology. Communication among nodes in these networks is accomplished via different routing protocols. But these protocols have different security flaws and using these flaws, an attacker can launch many attacks. Wormhole attack is one of the serious attacks in the context of mobile ad-hoc networks that can disrupt any routing channel completely. In this work, an attempt has been made to analyze and compare the performance of on-demand reactive routing protocol: Ad hoc On Demand Distance Vector (AODV) with two approaches: AODV without attack and AODV under wormhole attack using two mobility models viz. Random Way Point Model and Reference Point Group Mobility Model. The performance metrics evaluated for the two examined approaches are Average Throughput, Packet Delivery Ratio, Average End to End Delay and Jitter. Along with this, an approach has also been used to analyze participated malicious nodes.
SKOSYN: Simple Knowledge Organization System for synonym search on content management system

The development of Content Management System (CMS) technology undoubtedly eases website content organization. Creative writing is a common challenge in producing written content. One solution is to use synonyms, which conventionally can be found in a thesaurus. In this research, Simple Knowledge Organization System (SKOS) data model, which is suitable for organizing knowledge such as thesauri, is implemented as a plugin for searching synonyms in Bahasa Indonesia. This plugin will complement the default text editor on CMS to edit the written content in a convenient way. This plugin also provides a feature for getting definitions using the XML web service from Kateglo, so that users can understand exactly the meaning of synonyms they use. Based on experiments done in this research, SKOS data can be loaded into triplestore by ARC2 in shorter time than the regular MySQL database which uses integrity constraints. Moreover, the experiments have also shown that time stability for getting synonyms from triplestore using ARC2 can be more maintained than obtaining synonyms from XML document.
CHANGES IN SOIL MOISTURE AND PORE PRESSURE AFTER HARVESTING A FORESTED HILLSLOPE IN NORTHERN CALIFORNIA

ABSTRACT: In 1987, a 0.83-ha zero-order swale was instrumented with 58 pierometersand 25 tensiometers along several hillslope transects. Through 1993, soil moistureconditions were measured by pressure transducers connected to a digital data loggerrecording at 15-minute intervals.In August 1989, the 100-year-old second-growth forestin the swale was felled. Logs were removed by cable yarding and heavy logging equipmentwas excluded from the hillslopes. Increases in peak piezometric levels and soil moisturewere observed following logging.In the shallower, unsaturated portion of the soil profile,the increase was short-lived due to the rapid resprouting of redwood stumps. At thesoil-bedrock interface, increased pore pressures persisted during winter periods throughoutthe 4-yr post-harvest period.In addition to changes in evapotranspiration, pore pressureincreases may be explained by reduced canopy interception, compaction, or the collapse ofsoil pipes.At the base of the swale, pipeflow accounted for virtually all of the stormflow.After logging, soil pipes continued to efficiently route surplus stormflows through an existingpiping network and no slope instabilities were observed.KEY TERMS: hillslope hydrology, piezometer, soil moisture, timber harvest, soil piping.INTRODUCTIONThe impacts of timber harvesting on hydrologic processes are of great concern to landmanagers and the public in the Pacific Northwest. Many scientists have evaluated theeffects of logging on streamflow and sedimentation but much less work has been done onsubsurface flow processes.Slope stability problems arise on steep slopes where subsurfacedrainage is inefficient. The resultant mass erosion events are the major source ofsedimentation in this region.It is now known that logging roads can alter subsurface flowconditions and aggravate slope stability hazards (Megahan, 1972). It is not clear if timberfelling and skyline yarding alone can significantly affect the physical properties that governhillslope drainage processes.This study addresses this issue by comparing pre- and post-harvest pore pressure levels and soil moisture conditions on a steep hillslope within a zero-order basin in coastal northwestern California.
Integrating What and When Across the Primate Medial Temporal Lobe

Structures of the medial temporal lobe provide distinct but complementary signals to encode temporal-order information. Episodic memory or memory for the detailed events in our lives is critically dependent on structures of the medial temporal lobe (MTL). A fundamental component of episodic memory is memory for the temporal order of items within an episode. To understand the contribution of individual MTL structures to temporal-order memory, we recorded single-unit activity and local field potential from three MTL areas (hippocampus and entorhinal and perirhinal cortex) and visual area TE as monkeys performed a temporal-order memory task. Hippocampus provided incremental timing signals from one item presentation to the next, whereas perirhinal cortex signaled the conjunction of items and their relative temporal order. Thus, perirhinal cortex appeared to integrate timing information from hippocampus with item information from visual sensory area TE.
Drawing Area-Proportional Euler Diagrams Representing Up To Three Sets

Area-proportional Euler diagrams representing three sets are commonly used to visualize the results of medical experiments, business data, and information from other applications where statistical results are best shown using interlinking curves. Currently, there is no tool that will reliably visualize exact area-proportional diagrams for up to three sets. Limited success, in terms of diagram accuracy, has been achieved for a small number of cases, such as Venn-2 and Venn-3 where all intersections between the sets must be represented. Euler diagrams do not have to include all intersections and so permit the visualization of cases where some intersections have a zero value. This paper describes a general, implemented, method for visualizing all 40 Euler-3 diagrams in an area-proportional manner. We provide techniques for generating the curves with circles and convex polygons, analyze the drawability of data with these shapes, and give a mechanism for deciding whether such data can be drawn with circles. For the cases where non-convex curves are necessary, our method draws an appropriate diagram using non-convex polygons. Thus, we are now always able to automatically visualize data for up to three sets.
Rhetorical strategies of legitimation: the 9/11 Commission's public inquiry process

This research project seeks to explore aspects of the post-reporting phase of the public inquiry process. Central to the public inquiry process is the concept of legitimacy and the idea that a public inquiry provides and opportunity to re-legitimate the credibility of failed public institutions. The current literature asserts that public inquiries relegitimise through the production of authoritative narratives. As such, most of this scholarship has focused on the production of inquiry reports and, more recently, the reports themselves. However, in an era of accountability, and in the aftermath of such a poignant attack upon society, the production of a report may represent an apogee, but by no means an end, of the re-legitimation process. Appropriately, this thesis examines the post-reporting phase of the 9/11 Commission’s public inquiry process. The 9/11 Commission provides a useful research vehicle due to the bounded, and relatively linear, implementation process of the Commission’s recommendations. In little more than four months a majority of the Commission’s recommendations were passed into law. Within this implementation phase the dominant discursive process took place in the United States Congress. It is the legislative reform debates in the House of Representatives and the Senate that is the focus of this research project. The central research question is: what rhetorical legitimation strategies were employed in the legislative reform debates of the post-reporting phase of the 9/11 Commission’s public inquiry process? This study uses a grounded theory approach to the analysis of the legislative transcripts of the Congressional reform debates. This analysis revealed that proponents employed rhetorical strategies to legitimise a legislative ‘Call to Action’ narrative. Also, they employed rhetorical legitimation strategies that emphasised themes of bipartisanship, hard work and expertise in order to strengthen the standing of the legislation. Opponents of the legislation focused rhetorical de-legitimation strategies on the theme of ‘flawed process’. Finally, nearly all legislators, regardless of their view of the legislation, sought to appropriate the authoritative legitimacy of the Commission, by employing rhetorical strategies that presented their interests and motives as in line with the actions and wishes of the Commission.
Nutrient dynamics in the western Canadian Arctic. I. New production in spring inferred from nutrient draw-down in the Cape Bathurst Polynya

Ice-retreat from the Cape Bathurst Polynya occurred in late May and early June 2004, and was quickly followed by a decrease in dissolved nutrient concentration at the sea sur- face. Concentration plots of NO3 � versus PO4 3� , and Si(OH)4 versus NO3 � showed the ratios of nutrient uptake in the surface layer were in proportions expected for diatom growth (N:P 13.1:1; Si:N 1.8:1) and that water-column NO3 � was depleted before PO4 3� and Si(OH)4. The temporal changes in integrated nitrate, phosphate and silicate concentrations were well described by logis- tic models that showed maximum consumption rates of 11.8, 0.82, and 17.8 mmol m �2 d �1 , respec- tively, and a total seasonal draw-down of 210 ± 19 mmol NO3 � m �2 . If we include estimates of NO3 � supply by advection, nitrification and freshwater dilution, then the amount of NO3 � consumed could be 25�33% higher. Uptake of NO3 � above the 1% isolume was balanced by an equivalent (94%) increase in particulate N over a 15 d period beginning at ice break-up. Thus, the amount of particulate spring new production associated with NO3 � disappearance was estimated to be 16.1 ± 1.5 g C m �2 .
Development of New Modular Genetic Tools for Engineering the Halophilic Archaeon Halobacterium salinarum

Our ability to genetically manipulate living organisms is usually constrained by the efficiency of the genetic tools available for the system of interest. In this report, we present the design, construction and characterization of a set of four new modular vectors, the pHsal series, for engineering Halobacterium salinarum, a model halophilic archaeon widely used in systems biology studies. The pHsal shuttle vectors are organized in four modules: (i) the E. coli’s specific part, containing a ColE1 origin of replication and an ampicillin resistance marker, (ii) the resistance marker and (iii) the replication origin, which are specific to H. salinarum and (iv) the cargo, which will carry a sequence of interest cloned in a multiple cloning site, flanked by universal M13 primers. Each module was constructed using only minimal functional elements that were sequence edited to eliminate redundant restriction sites useful for cloning. This optimization process allowed the construction of vectors with reduced sizes compared to currently available platforms and expanded multiple cloning sites. Additionally, the strong constitutive promoter of the fer2 gene was sequence optimized and incorporated into the platform to allow high-level expression of heterologous genes in H. salinarum. The system also includes a new minimal suicide vector for the generation of knockouts and/or the incorporation of chromosomal tags, as well as a vector for promoter probing using a GFP gene as reporter. This new set of optimized vectors should strongly facilitate the engineering of H. salinarum and similar strategies could be implemented for other archaea.
Robust Stereo-Based Person Detection and Tracking for a Person Following Robot

This paper describes a stereo-based person detec- tion and tracking method for a mobile robot that can follow a specific person in dynamic environments. Many previous works on person detection use laser range finders which can provide very accurate range measurements. Stereo-based systems have also been popular, but most of them have not been used for controlling a real robot. We propose a detection method using depth templates of person shape applied to a dense depth image. We also develop an SVM-based verifier for eliminating false positive. For person tracking by a mobile platform, we formulate the tracking problem using the Extended Kalman filter. The robot continuously estimates the position and the velocity of persons in the robot local coordinates, which are then used for appropriately controlling the robot motion. Although our approach is relatively simple, our robot can robustly follow a specific person while recognizing the target and other persons with occasional occlusions. Index Terms— Person detection and tracking, Mobile robot, Stereo.
UMAN WAYFINDING IN UNFAMILIAR BUILDINGS : A SIMULATION WITH A COGNIZING AGENT

Existing cognitively based computational models for wayfinding focus primarily on the exploration of mental representations rather than the information needs for wayfinding. It is important to consider information needs because people trying to find their ways in unfamiliar environments do not have a previously acquired mental representation but depend on external information. The fundamental tenet of this work is that all information must be presented to the wayfinder at each decision point as “knowledge in the world. ” Simulating people’s wayfinding behavior in a cognitively plausible way requires the integration of structures for information perception and cognition in the underlying model. In this work we use a cognizing agent to simulate people’s wayfinding processes in unfamiliar buildings. The agent-based model consists of two tiers: simulated states of the environment and simulated beliefs of the agent. The agent is modeled with state, an observation schema, a specific wayfinding strategy, and commonsense knowledge. The environment is modeled as a graph, where nodes represent decision points and edges represent lines of movement. The perceptual wayfinding model integrates the agent and its environment within a “Sense-Plan-Act” framework. It focuses on knowledge in the world to explain actions of the agent. The concepts of affordance and information are used to describe the kinds of knowledge the agent derives from the world by means of visual perception. Affordances are possibilities for action with reference to the agent. Information is necessary for the agent to decide which affordances to utilize. During the navigation process the agent accumulates beliefs about the environment by observing task-relevant affordances and information at decision points. The utilization of a “go-to” affordance leads the agent from one node to another where it is again provided with percepts. A successful navigation corresponds to the agent’s traversal from a start to a goal node. The proposed formal specifications of the agent-based model can be used to simulate people’s wayfinding behavior in spatial information and design systems in a cognitively plausible way. Such simulation helps to determine where and why people face wayfinding difficulties and what needs to be done to avoid them. The case of wayfinding in an airport, in which the signage in the airport is tested, is employed to demonstrate the perceptual wayfinding model.
Activation of TRPV1 Contributes to Morphine Tolerance: Involvement of the Mitogen-Activated Protein Kinase Signaling Pathway

Tolerance to the analgesic effects of opioids occurs after their chronic administration, a pharmacological phenomenon that has been associated with the development of abnormal pain sensitivity such as hyperalgesia. In the present study, we investigated the role of TRPV1, which is crucial for the transduction of noxious chemical and thermal stimuli, in morphine tolerance and tolerance-associated thermal hyperalgesia. After chronic morphine treatment, a marked increase in TRPV1 immunoreactivity (IR) was detected in L4 dorsal root ganglion (DRG) neurons, spinal cord dorsal horn, and sciatic nerve. Real-time reverse transcription (RT)-PCR demonstrated that TRPV1 mRNA was upregulated in spinal cord and sciatic nerve but not in the DRG. Intrathecal pretreatment with SB366791 [N-(3-methoxyphenyl)-4-chlorocinnamide], a selective antagonist of TRPV1, attenuated both morphine tolerance and associated thermal hyperalgesia. Chronic morphine exposure induced increases in phosphorylation of mitogen-activated protein kinases (MAPKs), including p38 MAPK-IR, extracellular signal-regulated protein kinase (ERK)-IR, and c-Jun N-terminal kinase (JNK)-IR, in L4 DRG neurons. Intrathecal administration of the selective p38, ERK, or JNK inhibitors not only reduced morphine tolerance and associated thermal hyperalgesia but also suppressed the morphine-induced increase of TRPV1-IR in DRG neurons, spinal cord, and sciatic nerve and of mRNA levels in spinal cord and sciatic nerve. Together, we have identified a novel mechanism by which sustained morphine treatment results in tolerance and tolerance-associated thermal hyperalgesia, by regulating TRPV1 expression, in a MAPK-dependent manner. Thus, blocking TRPV1 might be a way to reduce morphine tolerance.
Leadership Style And Employee Attitudes In Turkish Management Culture

Leaders take on many different roles in organizational life and aim to reach the goals of the organization, provide coordination in the process of achieving success, balance with the environment and organize the internal dynamics of the organization. For the companies and the organizations operating in Turkey; social structures, values, beliefs, organizational culture has an influence on leadership styles, and it is important to examine leadership styles effects on determining the role stress and job performance of individuals in terms of the achieving the goals of the organization. In this study, in the context of behavioral leadership, in the Turkish management culture, the task and people-oriented leadership style's effects on job performance, role ambiguity, and role conflict are examined in a broader perspective. This study has been carried out in five medium and large sized enterprises operating in Kocaeli. The results suggest that people-oriented leadership style plays a significant role in reducing the role stress and increasing job performance in Turkish management culture. The findings of the study could provide a significant contribution to the managerial applications with the reduction of the role stress and the increase of the job performance of the employees. the internal consistency reliabilities of all variables measured in this study were quite respectable. The findings indicated that all the independent variables investigated were significantly related to job performance.
Research and implementation of social hot topic detection system based on mirco-blog

Micro-blog as an important part of the network media has become an important access to information for Netizens. Some hot topics have an immeasurable impact on the public opinion formation and dissemination, and also potential security risks are absolutely not underestimated. Collecting the relevant data in the micro-blog can provide data base for public opinion analysis. The study, social topic detection system based on micro-blog is mainly centered on the key technologies in the information capture and the Chinese handling of micro-blog. This study invokes the API of Sina micro-blog through three kinds of capture strategy, and then uses RMM reverse maximum matching algorithm to capture the information of microblog, after this using classification of self-build public opinion to do information classification of micro-blog for structured storage. At last this study finishes the research and implement of the system based on microblog. The system has realized the hot topics of timely capture, collection, classification, storage and retrieval which lay the foundation for further public opinion analysis.
An Algorithm of Generalization in Positive Supercompilation

This paper presents a termination technique for positive supercompilation, based on notions from term algebra. The technique is not particularily biased towards positive supercompilation, but also works for deforestation and partial evaluation. It appears to be well suited for partial deduction too. The technique guarantees termination, yet it is not overly conservative. Our technique can be viewed as an instance of Martens' and Gallagher's recent framework for global termination of partial deduction, but it is more general in some important respects, e.g. it uses well-quasi orderings rather than well-founded orderings. Its merits are illustrated on several examples.