Miracle-dz/UniFAR-FTUs huggingface dataset:
Deductive systems for BigData integration

The globalization is associated with an increased data to be processed from E-commerce transactions. The specialists are looking for different solutions, such as BigData, Hadoop, Datawarehoues, but it seems that the future is the predicative logic implemented through deductive database technology. It has to be done the swift from imperative languages, to not declaratively languages used for the application development. The deductive databases are very useful in the student teaching programs, too. Thus, the article makes a consistent literature review in the field and shows practical examples of using predicative logic in deductive systems, in order to integrate different kind of data types .
Emerging Market Bidder Returns and the Choice of Payment Method in Mergers and Acquisitions: Evidence from India

Consistent with other evidence on short-run effects of mergers and acquisitions (M&A) announcements on acquiring firm’s shareholder wealth in emerging markets, our study reveals that M&A deals in India, irrespective of the payment method, are not value destroying. Cash deals and stock deals create shareholder wealth on deal announcements. We offer ‘pseudo-cash deal hypothesis’ to explain this phenomenon. We also observe that bigger the relative size of the deal, greater is the abnormal return on deal announcements. We observe that acquirers with high promoter holdings are highly reluctant to offer stock when they acquire a majority stake. However, bigger deals, deals for listed target firms, and deals in the information technology sector, command stock offers. JEL Classification: G34, G14
Poly(l-lactide)/halloysite nanotube electrospun mats as dual-drug delivery systems and their therapeutic efficacy in infected full-thickness burns

In this study, poly(l-lactide) (PLLA)/halloysite nanotube (HNT) electrospun mats were prepared as a dual-drug delivery system. HNTs were used to encapsulate polymyxin B sulphate (a hydrophilic drug). Dexamethasone (a hydrophobic drug) was directly dissolved in the PLLA solution. The drug-loaded HNTs with optimised encapsulation efficiency were then mixed with the PLLA solution for subsequent electrospinning to form composite dual-drug-loaded fibre mats. The structure, morphology, degradability and mechanical properties of the electrospun composite mats were characterised in detail. The results showed that the HNTs were uniformly distributed in the composite PLLA mats. The HNTs content in the mats could change the morphology and average diameter of the electrospun fibres. The HNTs improved both the tensile strength of the PLLA electrospun mats and their degradation ratio. The drug-release kinetics of the electrospun mats were investigated using ultraviolet-visible spectrophotometry. The HNTs/PLLA ratio could be varied to adjust the release of polymyxin B sulphate and dexamethasone. The antibacterial activity in vitro of the mats was evaluated using agar diffusion and turbidimetry tests, which indicated the antibacterial efficacy of the dual-drug delivery system against Gram-positive and -negative bacteria. Healing in vivo of infected full-thickness burns and infected wounds was investigated by macroscopic observation, histological observation and immunohistochemical staining. The results indicated that the electrospun mats were capable of co-loading and co-delivering hydrophilic and hydrophobic drugs, and could potentially be used as novel antibacterial wound dressings.
Mother-to-child HIV transmissions in Israel, 1985–2011

SUMMARY Mother-to-child transmission (MTCT) is the leading cause of paediatric HIV-infection in Israel. This study aimed to assess MTCT rates and analyse temporal changes in relation to highly active antiretroviral therapy (HAART) introduction in 1996. This historical prospective study included all HIV-infected women who delivered in Israel between 1988 and 2011. Demographic, clinical, laboratory and therapy characteristics were compared between HIV-infected newborns with all others, and between infants born before and after 1996. Of all 796 infants born in Israel to HIV-infected women, 25 (3·1%) were infected. MTCT rates decreased significantly after HAART introduction compared with infants who were born before 1996 (16·3% vs. 1·7%). Mothers who infected vertically were more likely to be younger, Ethiopian-born, delivered trans-vaginally, not treated with HAART during pregnancy/labour and delivered before 1996 compared with mothers who did not transmit the HIV to their neonates. Newborns who did not receive antiretroviral therapy postpartum were more commonly HIV-infected and their mortality rate was higher. In conclusion, HAART during pregnancy/labour decreased MTCT significantly. Most MTCT in Israel was recorded among Ethiopian migrants, yet, in decreasing rates. Continuous efforts should be employed to encourage early HIV testing and allow effective HAART to pregnant women who belong to a key risk-group.
Merging and Simplification of Labour Legislation through Codes: The Process Needs to Draw Insights through Qualitative Research Initiatives

It may be difficult for the small and medium enterprises to deal with a large number of labour legislation but it is not adequately known as to what extent that affects large organisations, including MNCs. The multiplicity of labour legislation and overlapping of different legal provisions may create bottlenecks for both, the smooth industrial operations and harmonious relationship between the employers and employees. Also, it is predictable that merging of multiple labour laws into four codes may improve operational efficiency and relations in the industries across sectors. However, how far such codification will correlate with issues like jobless growth, employment generation, reviving manufacturing, contract labour conundrum, the creation of more salaried jobs etc.? There is very little empirical evidence or acceptable rationale to answer this question. Every major problem or issue in society and industry may not be resolved only through political and judiciary interventions. It requires insights through multidisciplinary studies, not primarily through analytics but with the help of grounded theory, ethnography, phenomenological study etc. If our efforts, especially initiatives for the codification of laws, fail to make the entire process inclusive, we may later experience disintegrative and adverse outcomes. This article aims to initiate a thought process to understand if qualitative research can substantially contribute to the process.
OS 21-02 CONNECTING TUBULE-GLOMERULAR FEEDBACK (CTGF) IN RENAL HEMODYNAMICS AND BLOOD PRESSURE REGULATION AFTER UNILATERAL NEPHRECTOMY (UNx)

Objective: Renal hemodynamics is critical for regulation of glomerular filtration (GFR), sodium excretion and blood pressure (BP), and it depends on myogenic response, tubuloglomerular feedback (TGF) and connecting tubule-glomerular feedback (CTGF). CTGF dilates afferent arteriole in response to high sodium in connecting tubule (CNT), counteracting and resetting TGF; and increasing the plasma flow and glomerular pressure favoring sodium excretion. CTGF is initiated by epithelial sodium channel (ENaC) activation in CNT and inhibited by ENaC blocker Benzamil. Unilateral nephrectomy (UNx) is accompanied by TGF resetting, increase in renal blood flow (RBF) and single nephron GFR in the remnant kidney, without any changes in systemic BP. We evaluated CTGF role in BP regulation and TGF resetting after UNx. Design and Method: UNx was performed on Sprague-Dawley rats and 24 h later TGF was evaluated in vivo by renal micropuncture using stop flow pressure (Psf) techniques. CTGF was evaluated by intratubularly adding Benzamil during the TGF response. Another set of animals received chronic kidney infusion of Benzamil that started 1 week before UNx. Renal blood flow (RBF) was measured by arterial spin labeling-MRI 24 h before and 24 h after the UNx. Direct BP measurement was performed before and 3 weeks after the UNx. Results: After UNx, TGF resetting was observed (delta-Psf 8 ± 1 vs. 1 ± 1 mmHg p < 0.05, Sham vs. Unx) and that was inhibited by Benzamil. RBF increased after the UNx in comparison to sham and this increase was inhibited by chronic infusion of Benzamil (Sham: 305 ± 59; UNx: 456 ± 34; UNx + Benzamil 346 ± 64 ml/min/100 g tissue p < 0.002). Mean BP values were not different between the vehicle or Benzamil infused rats before the UNx, however 3 weeks after the UNx, Benzamil infused rats showed higher mean BP values than vehicle (88 ± 0.3 vs. 97 ± 4 mmHg, p < 0.01). Conclusions: CTGF participates in TGF resetting and BP regulation after UNx. CTGF impairment could be a potential cause of hypertension.
[Short form of the WAIS-III for use with patients with schizophrenia].

The aim of this study is to obtain a sufficiently guaranteed, abridged, Spanish version of the WAIS-III and thereby reduce the time needed to administer the complete scale. Although the samples used were based both on normal individuals (41 participants with no known history of mental illness) as well as individuals diagnosed with schizophrenia (41 participants), the real focus of the study was the clinical group because this is where the greatest advantages can be obtained by shortening the time to administer the scale. The data demonstrates that the best combination of tests was: Similarities, Picture Completion, Digit Span and Digit Symbol-coding because, with this reduced form, it was possible to obtain a linear correlation between the IQ of the complete scale and that of the abridged form of . 91 in the clinical and . 86 in the control group. For both groups, the differences between the real IQ averages and the estimated ones were nonsignificant.
Cardiovascular and metabolic costs of forward, backward, and lateral motion.

PURPOSE The purpose of this study was to compare the metabolic and cardiovascular responses of movement in forward (FM), backward (BM), and lateral (LM) directions. METHODS Thirteen athletes with the following characteristics (mean +/- SD) were evaluated: age 21+/-3 yr, height 172.0+/-9.0 cm, weight 62.92+/-9.05 kg, and VO2max 54.13+/-7.42 mL x kg(-1) x min(-1). Subjects were evaluated at 80.45 and 134.08 m x min(-1). A repeated measures ANOVA was used for statistical analysis (P < 0.05). RESULTS At 80.45 m x min(-1), the following respective VO2 mL x kg(-1) x min(-1) and heart rate (HR) beats x min(-1) responses were: FM = 12.42+/-2.29, 113+/-10; BM = 15.95+/-2.45, 132+/-16; and LM = 22.10+/-4.76, 140+/-15. Both VO2 and HR were significantly different between conditions: LM > BM > FM. At 134.08 m x min(-1), the following respective VO2 and HR responses were: FM = 27.15+/-2.51, 146+/-7; BM = 31.33+/-5.77, 168+/-11; and LM = 32.58+/-5.74, 169+/-10. At 134.08 m x min(-1) neither HR or VO2 were significantly different between LM or BM (LM, BM, > FM). Stride length and stride frequency were also significantly different between conditions. These results indicate the variation in the energy cost of FM, BM, and LM.
Nuclear Matrix Attachment Regions and Transgene Expression in Plants

DNA sequences called matrix attachment regions (MARs) or scaffold attachment regions (SARs) have recently attracted much attention because of their perceived capacity to increase levels of transgene expression and reduce transformant-to-transformant variation of transgene expression in both plants and animals. Work with these sequences is in its early stages and data that seem to be contradictory have been presented. We do not intend to resolve these controversies here (this will be accomplished by further research). Rather, we will discuss the hypothesized role of MARs in chromatin structure, how MARs are isolated and characterized, what effects MARs have had on the expression of transgenes and the models that have been evoked to explain those effects.
Suppression of root nodule formation by artificial expression of the TrEnodDR1 (coat protein of White clover cryptic virus 1) gene in Lotus japonicus.

TrEnodDR1 (Trifolium repens early nodulin downregulation 1) encodes a coat protein of White clover cryptic virus 1. Its expression in white clover was down-regulated at the time when root nodules formed. We surmised that its artificial expression would interfere with root nodulation. Therefore, we investigated the effects of its artificial expression on the growth and root nodulation of Lotus japonicus (a model legume). Transformants were prepared by Agrobacterium spp. -mediated transformation. The growth of transformants was reduced and the number of root nodules per unit root length was greatly decreased relative to control. The concentration of endogenous abscisic acid (ABA), which controls nodulation, increased in plants containing TrEnodDR1. These phenotypes clearly were canceled by treatment with abamine, a specific inhibitor of ABA biosynthesis. The increase in endogenous ABA concentration explained the reduced stomatal aperture and the deformation of root hairs in response to inoculation of transgenic L. japonicus with Mesorhizobium loti. Transcriptome comparison between TrEnodDR1 transformants and control plants showed clearly enhanced expression levels of various defense response genes in transformants. These findings suggest that TrEnodDR1 suppresses nodulation by increasing the endogenous ABA concentration, perhaps by activating the plant's innate immune response. This is the first report of the suppression of nodulation by the artificial expression of a virus coat protein gene.
Interactions between macrophages and oxidized low density lipoprotein in the presence of type I collagen

In order to investigate the influence of collagen on the interactions between macrophages and oxidatively modified low density lipoprotein (ox‐LDL), type I collagen was isolated from rat tail tendon and prepared as a gel. The binding of 125I‐ox‐LDL, 125I‐malondialdehyde (MDA)‐LDL and 125I‐acetyl‐LDL to collagen was higher but the binding of 125I‐4‐hydroxynonenal (HNE)‐LDL was lower than that of native 125I‐LDL. When mouse peritoneal macrophages were cultivated on this collagen gel, most of the modified LDL was bound to the collagen gel rather than taken up by macrophages. The amount of modified 125I‐LDL degraded by the macrophages decreased in the presence of the collagen gel. In the absence of gel a similar degree of reduction in degradation of modified 125I‐LDL by macrophages was obtained when the cells were treated with cytochalasin D, an inhibitor of non‐specific phagocytosis. However, the treatment of the macrophages cultivated on the collagen gel with cytochalasin D did not influence the degradation of 125I‐ox‐LDL and 125I‐HNE‐LDL. These results suggest that the uptake of ox‐LDL by macrophages grown on collagen gels is primarily mediated via the scavenger receptors pathway, whereas in the absence of collagen also other mechanisms of uptake are operating.
Community Custodians of Popular Music's Past: A DIY Approach to Heritage

This book examines do-it-yourself (DIY) approaches to the collection, preservation, and display of popular music heritage being undertaken by volunteers in community archives, museums and halls of fame globally. DIY institutions of popular music heritage are much more than ‘unofficial’ versions of ‘official’ institutions; rather, they invoke a complex network of affect and sociality, and are sites where interested people – often enthusiasts – are able to assemble around shared goals related to the preservation of and ownership over the material histories of popular music culture. Drawing on interviews and observations with founders, volunteers and heritage workers in 23 DIY institutions in Australasia, Europe and North America, the book highlights the potentialities of bottom-up, community-based interventions into the archiving and preservation of popular music’s material history. It reveals the kinds of collections being housed in these archives, how they are managed and maintained, and explores their relationship to mainstream heritage institutions. The study also considers the cultural labor of volunteers in the DIY institution, arguing that while these are places concerned with heritage management and the preservation of artefacts, they are also extensions of musical communities in the present in which activities around popular music preservation have personal, cultural, community and heritage benefits. By looking at volunteers’ everyday interventions in the archiving and curating of popular music’s material past, the book highlights how DIY institutions build upon national heritage strategies at the community level and have the capacity to contribute to the democratization of popular music heritage. This book will have a broad appeal to a range of scholars in the fields of popular music studies, musicology, ethnomusicology, archive studies and archival science, museum studies, critical heritage studies, cultural studies, cultural sociology and media studies.
Ragged Red Fibers in Normal Aging and Inflammatory Myopathy

Ragged red fibers are an important marker for mitochondrial disease. To evaluate the hypothesis that mitochondrial dysfunction may play a role in the pathogensis of aging and inclusion body myositis, we studied the frequency of ragged red fibers in muscle biopsy specimens from 15 young and 13 old normal adults, and from 27 patients with inclusion body myositis, polymyositis, or dermatomyositis. Serial transverse cryostat sections were stained with modified Gomori trichrome, modified succinic dehydrogenase, and cytochrome c oxidase. The frequency of ragged red fibers, determined by measuring the percent number of succinic dehydrogenase–positive ragged red fiber equivalents, was significantly higher in old compared to young normal subjects (0.33 vs. 0.02%, p < 0.0001). With the exception of a single polymyositis biopsy specimen showing a large number of ragged red fibers, the frequency of ragged red fibers in patients with polymyositis or dermatomyositis was similar to that of age‐matched normal control subjects. The frequency of ragged red fibers was more than 1% in 7 of 8 patients with inclusion body myositis (maximum, 15%). The modified succinic dehydrogenase stain was more sensitive than the modified Gomori trichrome in detecting accumulation of mitochondria in muscle fibers. Cytochrome c oxidase activity was deficient in most ragged red fibers. We conclude that the number of ragged red fibers increases with normal aging and may reflect an age‐related decline in muscle mitochondrial oxidative metabolism. The frequent occurrence of ragged red fibers in inclusion body myositis suggests that mitochondrial function may be impaired in this disease.
Beyond Copenhagen: The Political Economy of Securitising “Outside Influences” in Bali

ABSTRACT Securitisation theory has contributed greatly to critical security studies. However, the Copenhagen School’s focus on discursive analysis fails to answer the “so what” question of why issues are securitised and for whose benefit. This article contends that more nuanced explanations can be provided by taking seriously the political economy context within which the process of securitisation is embedded. The article has two aims. First, it contributes to further refining securitisation theory by embedding Balzacq’s pragmatic act – which implies that securitising actors gain the assent of an audience based on a shared view of vulnerabilities – within a broad social conflict analysis. This latter can explain the socio-political struggles that create popular support for securitisation, and what social groups benefit from it. Second, it contributes to explanations of Bali’s contemporary political economy by operationalising the refined approach to explain how struggles over the spoils of tourism have created a receptive audience among a cross-class section of Balinese for the securitisation of “outside influences” – a euphemism for migrants, non-local investors and Western cultural influences. Securitisation has resulted in conservative elite groups marginalising progressive voices; “traditional” institutions being favoured in accessing state resources; and in a policing landscape in which migrants are harassed and exploited.
Subsidiary initiative effect in enterprise groups network: How initiatives drive network embeddedness dynamic changes?

This paper researches on subsidiary initiatives' network effect, and mainly analyzes the dynamic relationships of both internal and external subsidiary initiative and subsidiary network embeddedness. On the view that enterprise groups are embedded in informal network structures, this paper laid a theoretical foundation for the research on subsidiary initiative mechanism and its inherent law. This paper put forward three key proposition: (1) internal network embeddedness create conditions for subsidiary implementing internal initiatives; and consider the network marginal effect, we have (2) Based on rational principles, subsidiaries which implement external initiatives will reduce its network embeddedness, and (3) Subsidiaries who obey rational principles of the subsidiary wouldn't infinitely increase its network embeddedness in enterprise groups. Finally, this study is based on a case study analyse of Hisense Group, through annual reports data of public companies and questionnaire surveys with key initiative and embeddedness information, and the result provides preliminary support for the hypothesized effect of subsidiary initiatives.
Genetic structure and assignment tests demonstrate illegal translocation of red deer (Cervus elaphus) into a continuous population

Molecular forensic methods are being increasingly used to help enforce wildlife conservation laws. Using multilocus genotyping, illegal translocation of an animal can be demonstrated by excluding all potential source populations as an individual's population of origin. Here, we illustrate how this approach can be applied to a large continuous population by defining the population genetic structure and excluding suspect animals from each identified cluster. We aimed to test the hypothesis that recreational hunters had illegally introduced a group of red deer into a hunting area in Luxembourg. Reference samples were collected over a large area in order to test the possibility that the suspect individuals might be recent immigrants. Due to isolation‐by‐distance relationships in the data set, inferring the number of genetic clusters using Bayesian methods was not straightforward. Biologically meaningful clusters were only obtained by simultaneously analysing spatial and genetic information using the program baps 4.1. We inferred the presence of three genetic clusters in the study region. Using partial Mantel tests, we detected barriers to gene flow other than distance, probably created by a combination of urban areas, motorways and a river valley used for viticulture. The four focal animals could be excluded with a high certainty from the three genetic subpopulations and it was therefore likely that they had been released illegally.