Miracle-dz/UniFAR-FTUs huggingface dataset:
Measurement of Job Satisfaction in Nursing School Teachers: Confirmatory Factor Analysis of a Job Satisfaction Scale Based on the Stamps Scale

Teachers in nursing schools, unlike those in nursing faculties in universit ies, have to play mult iple roles, which causes frequent burnout and a potential turnover problem. A measure of job satisfaction is thus needed to obtain clear and subjective perceptions of the work environ ment and to develop better working conditions. We transformed the Revised Attitude Scale Items to Measure Occupational Satisfaction of Hospital Nurses (Stamps, P. L., et al., 1978; Ozaki, F. & Tadamasa, T., 1988) for clin ical nurses into a scale for nursing teachers by shortening and rewording 30 selected items. The dimensional structure of the original six-factor model was investigated by using three samples of Japanese nursing teachers of different ages (n = 303; 30s =73, 40s=152, over 50=78), wh ich resulted in the elimination of the "Task" factor fro m the hypothesized six-factor structure. The revised five-factor model was retained although its fit toa cross-validated sample was not satisfactory. However, in an exploratory analysis, we examined the non-invariance of all parameters and foundthat two itemswere not invariant across the groups. Based on the results of the analysis,we offered several suggestions to modify items in the scale for practical use.
Components of Expertise

This article discusses frameworks for studying expertise at the knowledge level and knowledge-use level. It reviews existing approaches such as inference structures, the distinction between deep and surface knowledge, problem-solving methods, and generic tasks. A new synthesis is put forward in the form of a componential framework that stresses modularity and an analysis of the pragmatic constraints on the task. The analysis of a rule from an existing expert system (the Dipmeter Advisor) is used to illustrate the framework.
Cytokinin as a mediator for regulating root system architecture in response to environmental cues

Root system architecture (RSA) is developmentally controlled by genetic pathways and their interaction with various environmental cues, in particular soil conditions. One important player in shaping RSA is the hormone cytokinin, which acts as a negative regulator of root elongation and branching. The redundant roles of cytokinin metabolism and signaling genes of Arabidopsis thaliana in regulating early stages of lateral root formation has recently been shown and it has been proposed that this redundancy reflects a role in mediating different environmental cues. Here we report that the transcript levels of cytokinin genes in the root responds to changes in nutrient availability in distinct ways. IPT3, IPT5, CYP735A2, LOG5, and CKX4 are particularly responsive cytokinin metabolism genes, genes encoding different type-A response regulators and the transcriptions factor genes ARR10 and CRF6 are among the most responsive signaling genes. This finding supports the hypothesis that environmental cues operate through fine-tuned transcriptional regulation of cytokinin genes to modulate root development.
The Complete Genome of a New Betabaculovirus from Clostera anastomosis

Clostera anastomosis (Lepidoptera: Notodontidae) is a defoliating forest insect pest. Clostera anastomosis granulovirus-B (ClasGV-B) belonging to the genus Betabaculovirus of family Baculoviridae has been used for biological control of the pest. Here we reported the full genome sequence of ClasGV-B and compared it to other previously sequenced baculoviruses. The circular double-stranded DNA genome is 107,439 bp in length, with a G+C content of 37.8% and contains 123 open reading frames (ORFs) representing 93% of the genome. ClasGV-B contains 37 baculovirus core genes, 25 lepidopteran baculovirus specific genes, 19 betabaculovirus specific genes, 39 other genes with homologues to baculoviruses and 3 ORFs unique to ClasGV-B. Hrs appear to be absent from the ClasGV-B genome, however, two non-hr repeats were found. Phylogenetic tree based on 37 core genes from 73 baculovirus genomes placed ClasGV-B in the clade b of betabaculoviruses and was most closely related to Erinnyis ello GV (ErelGV). The gene arrangement of ClasGV-B also shared the strongest collinearity with ErelGV but differed from Clostera anachoreta GV (ClanGV), Clostera anastomosis GV-A (ClasGV-A, previously also called CaLGV) and Epinotia aporema GV (EpapGV) with a 20 kb inversion. ClasGV-B genome contains three copies of polyhedron envelope protein gene (pep) and phylogenetic tree divides the PEPs of betabaculoviruses into three major clades: PEP-1, PEP-2 and PEP/P10. ClasGV-B also contains three homologues of P10 which all harbor an N-terminal coiled-coil domain and a C-terminal basic sequence. ClasGV-B encodes three fibroblast growth factor (FGF) homologues which are conserved in all sequenced betabaculoviruses. Phylogenetic analysis placed these three FGFs into different groups and suggested that the FGFs were evolved at the early stage of the betabaculovirus expansion. ClasGV-B is different from previously reported ClasGV-A and ClanGV isolated from Notodontidae in sequence and gene arrangement, indicating the virus is a new notodontid betabaculovirus.
(Z)-Ethyl 2-(2,4-dimethylbenzylidene)-7-methyl-3-oxo-5-phenyl-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate

In the title compound, C25H24N2O3S, the dihedral angles between the thiazole ring and the phenyl and substituted benzene rings are 84.91 (11) and 11.58 (10)°, respectively. The dihydropyrimidine ring adopts a flattened boat conformation. The olefinic double bond is in a Z configuration.
Smart optical components based on liquid-liquid interface manipulation by dielectric force

Two smart optical components, which composed of two immiscible dielectric liquids, were introduced in this article. The liquid-liquid interface manipulation by dielectric force was applied to achieve the adaptive optical function, including variable focal length and variable aperture. The maximum optical power change of the experimental dielectric liquid lens was up to 91 diopter (D) while the actuation voltage was turned to 41 Vrms. Meanwhile, its maximum power consumption lowered than 0.4 mW. A variable focus dielectric liquid lens enables to change the effective focus length of a lens module. That can be used in the application of auto-focusing or zoom. A 2 megapixel compact camera module integrated with a dielectric liquid lens showed its ability to focus at variable distance. Its minimal focus distance achieves to be 1cm. A dielectric liquid iris was demonstrated its ability to control the amount of passing light. The aperture turning ratio was up to 65% and the transparent of its opening area was up to 85%.
Psychosocial Occupational Therapy Interventions for Substance-Use Disorders: A Narrative Review

ABSTRACT The review was conducted to explore psychosocial interventions for adults with substance-use disorders. A refined literature focus was placed on articles published by occupational therapists, or articles published by an allied health professional, that discussed occupational therapy performing the intervention. Ten articles met inclusion criteria, all focusing on aspects of life skills training. Study results support the professions’ ability to enhance functional independence and occupational performance for individuals recovering from substance use. Further, a more controlled investigation is warranted to further define occupational therapy’s scope within substance-use disorder treatment.
Activation of the Non-receptor Tyrosine Kinase cSrc in Macrophage-rich Atherosclerotic Plaques of Human Carotid Arteries

To determine the involvement of the non-receptor tyrosine kinase cSrc in plaque destabilization in carotid atherosclerosis (CAS), which is responsible for cerebral infarction, we performed quantitative and morphological detection of phosphorylated active cSrc (p-cSrc) and histopathological examination in CAS lesions. We examined carotid endarterectomy specimens obtained from 32 CAS patients. Each specimen was used for immunoblot and immunohistochemical analyses of p-cSrc, histopathological analysis, and image analysis of macrophage content. There was a strong positive correlation between cSrc activation on blots and macrophage content on sections. When we defined the macrophage-rich plaque (MRP) and the macrophage-poor plaque (MPP) as having macrophage content more and less than 5%, respectively, the p-cSrc density and the occurrence of plaque hemorrhage and thrombus formation were significantly increased in the MRP group (n=18) compared to the MPP group (n=14). p-cSrc immunoreactivity was localized in lesional endothelial cells, macrophages, and smooth muscle cells, which contained proinflammatory substances: the upstream oxidized low density lipoprotein, tissue factor and osteopontin, and the downstream active forms of extracellular signal-activated kinase and p38 and nuclear factor-κB. Our results suggest that cSrc activation in lesional cells contributes to plaque destabilization in CAS via persistent inflammation.
Robust clustering algorithm for high dimensional data classification based on multiple supports

High dimensionality, noisy features and outliers can cause problems in cluster analysis. Many existing methods can handle one of the problems well but not the others. In this paper, we propose a new clustering algorithm to solve these problems. The basic idea is to control the support of the optimization procedure so that the effect produced by those contaminated samples and dimensions is greatly reduced. This is achieved by using multiple supports. Initially, a large support is used and then its size is reduced and eventually only a subgroup of data samples is considered for clustering. This procedure can filter out lots of contaminated information. Experiment results show that the proposed method effectively resolves all these problems. It outperforms existing ones for real world high dimensional datasets.
Sequential Non-Rigid Structure from Motion Using Physical Priors

We propose a new approach to simultaneously recover camera pose and 3D shape of non-rigid and potentially extensible surfaces from a monocular image sequence. For this purpose, we make use of the Extended Kalman Filter based Simultaneous Localization And Mapping (EKF-SLAM) formulation, a Bayesian optimization framework traditionally used in mobile robotics for estimating camera pose and reconstructing rigid scenarios. In order to extend the problem to a deformable domain we represent the object's surface mechanics by means of Navier's equations, which are solved using a Finite Element Method (FEM). With these main ingredients, we can further model the material's stretching, allowing us to go a step further than most of current techniques, typically constrained to surfaces undergoing isometric deformations. We extensively validate our approach in both real and synthetic experiments, and demonstrate its advantages with respect to competing methods. More specifically, we show that besides simultaneously retrieving camera pose and non-rigid shape, our approach is adequate for both isometric and extensible surfaces, does not require neither batch processing all the frames nor tracking points over the whole sequence and runs at several frames per second.
“The child can remember your voice”: parent–child communication about sexuality in the South African context

There is a wealth of research on parent–child communication about sexual and reproductive health and rights (SRHR) and its influence on young people’s sexual behaviours. However, most of it is from the global North. The aim of this study was to explore parent–child communication in three South African provinces: Eastern Cape, KwaZulu-Natal (KZN) and Mpumalanga. Nine, peer, focus group discussions (FGDs) were conducted with young and adult black African men and women in their spoken languages. Data were analysed thematically. Findings revealed that cultural and religious constructions of taboo silenced direct communication and restricted the discussed topics. Parents’ older age, low educational level, lack of knowledge, and discomfort in talking about sexuality matters were reported to restrict conversations with children about sex and sexuality. The influence of these factors differed for parents residing in an urban setting who were more liberal than their counterparts residing in more rural areas. The child’s age and gender were also reported to be a consideration in approaching these conversations. There is a need for interventions to assist parents on how to communicate with their children about SRHR topics beyond pregnancy and HIV/AIDS. These interventions should take into account and address factors that seem to influence parent–child communication.
SOME n-RECTANGLE NONCONFORMING ELEMENTS FOR FOURTH ORDER ELLIPTIC EQUATIONS

In this paper, three n-rectangle nonconforming elements are proposed with n � 3. They are the extensions of well-known Morley element, Adini element and Bogner-Fox-Schmit element in two spatial dimensions to any higher dimensions respectively. These elements are all proved to be convergent for a model biharmonic equation in n dimensions.
Genetic analysis of a human rotavirus that belongs to subgroup I but has an RNA pattern typical of subgroup II human rotaviruses

We have previously found (O. Nakagomi, T. Nakagomi, H. Oyamada, and T. Suto, J. Med. Virol. 17:29-34, 1985), during an epidemiological study in Japan, a novel human rotavirus that belongs to subgroup I but has a long RNA pattern typical of subgroup II human rotaviruses. From the stool specimen containing this virus, we successfully isolated in MA104 cells a rotavirus, designated AU-1, which possesses these novel characteristics. The possibility that strain AU-1 was a laboratory contaminant of an animal rotavirus previously adapted to tissue culture cells was ruled out, and the identity of the AU-1 strain was established. Genetic analysis by RNA-RNA hybridization revealed that the AU-1 strain is not a simple reassortant between subgroup I and II human rotaviruses but that it shares a high level of sequence homology only with the gene encoding VP7 (the major neutralization protein) of serotype 3 human rotaviruses. Weak homology of the genomic RNA segments was also observed between the AU-1 strain and animal rotavirus strains, including rhesus rotavirus strain RRV and bovine rotavirus strain NCDV. These results suggest that the AU-1 strain may be an animal rotavirus that infected a human.
The Stem Cell Marker CD133 Associates with Enhanced Colony Formation and Cell Motility in Colorectal Cancer

CD133 is a membrane molecule that has been, controversially, reported as a CSC marker in colorectal cancer (CRC). In this study, we sought to clarify the expression and role of CD133 in CRC. Initially the size of the CD133−expressing (CD133+) population in eight well-described CRC cell lines was measured by flow cytometry and was found to range from 0% to >95%. The cell line HT29 has a CD133+ population of >95% and was chosen for functional evaluation of CD133 after gene knockdown by RNA interference. A time course assay showed that CD133 inhibition had no significant effect on cell proliferation or apoptosis. However, CD133 knockdown did result in greater susceptibility to staurosporine-induced apoptosis (p = 0.01) and reduction in cell motility (p<0.04). Since gene knockdown may cause “off-target” effects, the cell line SW480 (which has a CD133+ population of 40%) was sorted into pure CD133+ and CD133− populations to allow functional comparison of isogenic populations separated only by CD133 expression. In concordance with the knockdown experiments, a time course assay showed no significant proliferative differences between the CD133+/CD133− populations. Also greater resistance to staurosporine-induced apoptosis (p = 0.008), greater cell motility (p = 0.03) and greater colony forming efficiency was seen in the CD133+ population than the CD133− population in both 2D and 3D culture (p<0.0001 and p<0.003 respectively). Finally, the plasticity of CD133 expression in tumour cells was tested. Quantitative PCR analysis showed there was transcriptional repression in the CD133− population of SW480. Prolonged culture of a pure CD133− population resulted in re-emergence of CD133+ cells. We conclude that CD133 expression in CRCs is associated with some features attributable to stemness and that there is plasticity of CD133 expression. Further studies are necessary to delineate the mechanistic basis of these features.
Proteum - A Tool for the Assessment of Test Adequacy for C Programs User's guide

This technical report presents the main features of Proteum (Program Testing Using Mutants), a testing tool that supports Mutation Analysis criterion. Proteum can be configured for testing programs in many procedural programming languages. This guide reports the version 1.1-C that works with the C language on SUN workstations, under OPENWINDOWS environment. Proteum has been developed at University of São Paulo (USP), São Carlos, SP, Brazil [DEL93] and used in teaching and researching activities at USP and at SERC/Purdue University. ii Acknowledgment
Optimizing antenna configuration for MIMO systems with imperfect channel estimation

We study the optimal antenna configuration (i.e. number of transmit and receive antennas) for multiple-input multiple-output systems in pilot-symbol-assisted modulation schemes with imperfect channel estimation. We assume block flat-fading channels and focus on a practical range of high signal-to-noise ratio. An ergodic capacity lower bound is used as the objective function to be maximized. We analytically study the capacity gain from adding extra antennas to the transmitter or to the receiver in two different scenarios. Our numerical results show that the optimal antenna configuration under imperfect channel estimation can be significantly different from that under perfect channel estimation assumption. In addition, we investigate the capacity gain from optimizing antenna configuration and find that the gain can be larger than that achieved by optimizing transmit power over pilot and data symbols, particularly for large block lengths.
The Non-Canonical Wnt/PKC Pathway Regulates Mitochondrial Dynamics through Degradation of the Arm-Like Domain-Containing Protein Alex3

The regulation of mitochondrial dynamics is vital in complex cell types, such as neurons, that transport and localize mitochondria in high energy-demanding cell domains. The Armcx3 gene encodes a mitochondrial-targeted protein (Alex3) that contains several arm-like domains. In a previous study we showed that Alex3 protein regulates mitochondrial aggregation and trafficking. Here we studied the contribution of Wnt proteins to the mitochondrial aggregation and dynamics regulated by Alex3. Overexpression of Alex3 in HEK293 cells caused a marked aggregation of mitochondria, which was attenuated by treatment with several Wnts. We also found that this decrease was caused by Alex3 degradation induced by Wnts. While the Wnt canonical pathway did not alter the pattern of mitochondrial aggregation induced by Alex3, we observed that the Wnt/PKC non-canonical pathway regulated both mitochondrial aggregation and Alex3 protein levels, thereby rendering a mitochondrial phenotype and distribution similar to control patterns. Our data suggest that the Wnt pathway regulates mitochondrial distribution and dynamics through Alex3 protein degradation.
SMAA: Enhanced Subpixel Morphological Antialiasing

We present a new image‐based, post‐processing antialiasing technique, which offers practical solutions to the common, open problems of existing filter‐based real‐time antialiasing algorithms. Some of the new features include local contrast analysis for more reliable edge detection, and a simple and effective way to handle sharp geometric features and diagonal lines. This, along with our accelerated and accurate pattern classification allows for a better reconstruction of silhouettes. Our method shows for the first time how to combine morphological antialiasing (MLAA) with additional multi/supersampling strategies (MSAA, SSAA) for accurate subpixel features, and how to couple it with temporal reprojection; always preserving the sharpness of the image. All these solutions combine synergies making for a very robust technique, yielding results of better overall quality than previous approaches while more closely converging to MSAA/SSAA references but maintaining extremely fast execution times. Additionally, we propose different presets to better fit the available resources or particular needs of each scenario.
A Fatal Combination: A Thymidylate Synthase Inhibitor with DNA Damaging Activity

2′-deoxy-5-ethynyluridine (EdU) has been previously shown to be a cell poison whose toxicity depends on the particular cell line. The reason is not known. Our data indicates that different efficiency of EdU incorporation plays an important role. The EdU-mediated toxicity was elevated by the inhibition of 2′-deoxythymidine 5′-monophosphate synthesis. EdU incorporation resulted in abnormalities of the cell cycle including the slowdown of the S phase and a decrease in DNA synthesis. The slowdown but not the cessation of the first cell division after EdU administration was observed in all of the tested cell lines. In HeLa cells, a 10 μM EdU concentration led to the cell death in the 100% of cells probably due to the activation of an intra S phase checkpoint in the subsequent S phase. Our data also indicates that this EdU concentration induces interstrand DNA crosslinks in HeLa cells. We suppose that these crosslinks are the primary DNA damage resulting in cell death. According to our results, the EdU-mediated toxicity is further increased by the inhibition of thymidylate synthase by EdU itself at its higher concentrations.
Selectable retrovirus vectors encoding Friend virus gp55 or erythropoietin induce polycythemia with different phenotypic expression and disease progression

The Friend spleen focus-forming virus induces a massive expansion of erythroid progenitor cells resulting in polycythemia and splenomegaly. The pathogenic agent is the membrane glycoprotein gp55, encoded by the env gene. Recent evidence indicates that gp55 binds to and activates the erythropoietin (Epo) receptor. It is not clear, however, whether gp55 completely mimics the natural receptor ligand (Epo). To directly compare both effectors, we constructed selectable retroviral vectors which carry either the env or the Epo gene. The selection marker allowed for clonal analysis of infected cells. After infection of DBA/2J mice, the spleen weight, hematological indices, and Epo titer of peripheral blood were monitored. Although both viruses induced an acute erythrocytosis, there were significant differences in disease phenotype and progression. The Epo virus caused an enhanced increase of hematocrit and erythrocytes, whereas with the env virus the pool of late progenitors (CFU-erythroid) was dramatically expanded, resulting in a more severe splenomegaly. The distribution of cytologically recognizable erythroid precursors was shifted towards immature cell types by the env vector compared with Epo. These data suggest that Epo and gp55 differentially affect proliferation and differentiation. Gp55 appears to promote proliferation over differentiation, whereas Epo preferentially drives differentiation.
What is the Kalman Filter and How can it be used for Data Fusion ?

Just to explain a little about the motivation for this topic, the project I was working on was called “PROSPECT: Wide Area Prospecting Using Supervised Autonomous Robots. ” Our goal was to develop a semi-autonomous mutli-robot supervision architecture. One of the major issues for rover navigation is knowing attitude and position. Our initial idea was to use a combination of IMU, GPS and odometry (encoders and visual) to solve this issue. So for my math project, I wanted to explore using the Kalman Filter for attitude tracking using IMU and odometry data.