Miracle-dz/UniFAR-FTUs huggingface dataset:
High diversity achievement algorithm for dual carrier modulation in MB-OFDM UWB systems

In this paper, we propose a high diversity achievement algorithm for dual carrier modulation (DCM) in multiband-orthogonal frequency division multiplexing (MB-OFDM) ultrawideband (UWB) systems. The proposed algorithm uses additional precoding to the conventional DCM symbols with 25 subcarrier separation. The proposed algorithm exploits not only frequency diversity between 50 subcarrier separation by using DCM, but also frequency diversity between 25 subcarrier separation by using additional precoding, resulting in better performance than the conventional DCM. We also propose a method for detecting the proposed algorithm by sharing the modified dual carrier modulation (MDCM) detection block which is basically included MB-OFDM UWB systems. The proposed detection method prevents the increase in hardware complexity caused by additional precoding. Simulation results show that the performance of the proposed algorithm was improved by 3 dB in CM1 at an uncoded BER of 10-5, compared to DCM.
Composing Synchronization and Real-Time Constraints

There have been a number of publications illustrating the successes of object-oriented techniques in creating highly reusable software systems. Several concurrent languages have been proposed for specifying reusable synchronization specifications. Recently, a number of real-time object-oriented languages have been introduced for building object-oriented programs with real-time behavior. Composing and reusing object-oriented programs with both synchronization and real-time constraints has not been addressed adequately, although most real-time systems are concurrent. This paper analyzes the origins of the problems in composing and reusing synchronization and real-time specifications, first as separate concerns, and later as composed behavior. To overcome the so-called inheritance anomaly problems, this paper proposes modular and composable synchronization and real-time specification extensions to the object-oriented model. The applicability of the proposed mechanisms is illustrated through a number of examples.
Targeting EZH2 regulates tumor growth and apoptosis through modulating mitochondria dependent cell-death pathway in HNSCC

EZH2 is a negative prognostic factor and is overexpressed or activated in most human cancers including head and neck squamous cell carcinoma (HNSCC). Analysis of The Cancer Genome Atlas (TCGA) HNSCC data indicated that EZH2 over-expression was associated with high tumor grade and conferred poor prognosis. EZH2 inhibition triggered cell apoptosis, cell cycle arrest and decreased cell growth in vitro. MICU1 (mitochondrial calcium uptake1) was shown to be down regulated when EZH2 expression was inhibited in HNSCC. When the EZH2 and MICU1 were inhibited, HNSCC cells became susceptible to cell cycle arrest and apoptosis. Mitochondrial membrane potential and cytosolic Ca2+ concentration analysis suggested that EZH2 and MICU1 were required to maintain mitochondrial membrane potential stability. A xenograft tumor model was used to confirm that EZH2 depletion inhibited HNSCC cell growth and induced tumor cell apoptosis. In summary, EZH2 is a potential anti-tumor target in HNSCC.
Behavioral responses to a repetitive shadow stimulus express a persistent state of defensive arousal in Drosophila

William T. Gibson1,2,3, Carlos R. Gonzalez3, Conchi M. Fernandez3, Lakshmi Ramasamy4, Tanya Tabachnik4, Rebecca R. Du2, Panna E. Felsen3, Michael M. Maire3, Pietro Perona3, and David J. Anderson1,2,4 William T. Gibson: wtgibson@caltech.edu; David J. Anderson: wuwei@caltech.edu 1Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125, USA 2Division of Biology & Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA
A Mixed Reality System for Kansei-Based Co-Design of Highly-Customized Products

5 We designed a new Computer-Aided Design tool that can be easily and intuitively used by non-expert designers, like 6 users of the products being designed. The target application is the design of highly-customized products together with 7 the final users, more specifically the design of walking assistive devices with mobility-impaired people. The tool has 8 simultaneously been developed with an ad-hoc protocol for an accurate evaluation of the satisfaction of users, through 9 questionnaires and psychophysiological measurements. In fact, costly and complex technical products such as walking 10 assistance devices require ad-hoc design processes to address the specific needs of each user. The characterization of 11 user requirements in the early stage of design remains difficult due to their subjective and communication gap between 12 the user and the designer. To overcome these issues, we propose a new modular digital toolbox that allows co-design 13 between users and designers. The tool is a combination of a mixed reality hardware/software system and kansei (or 14 affective) engineering techniques. The hardware consists of modular Tangible User Interfaces (TUIs), custom-made 15 by 3D printing and powered by a 3D game engine. The interactive content is displayed in mixed reality, simultaneously 16 to the user and the designer. Kansei data of the users are collected through questionnaires and psychophysical 17 measurements, during multiple collaboration phases.
Cross-lingual Model Transfer Using Feature Representation Projection

We propose a novel approach to crosslingual model transfer based on feature representation projection. First, a compact feature representation relevant for the task in question is constructed for either language independently and then the mapping between the two representations is determined using parallel data. The target instance can then be mapped into the source-side feature representation using the derived mapping and handled directly by the source-side model. This approach displays competitive performance on model transfer for semantic role labeling when compared to direct model transfer and annotation projection and suggests interesting directions for further research.
An efficient feature selection method using named entity recognition for Chinese text categorization

Feature selection is an important task for text categorization. Traditional feature selection methods are based on terms but they may lose some useful information in texts. In this paper, we present a feature selection method that considers not only general terms but also named entities. Corresponding to our feature selection method, we propose a term weighting scheme for named entities. The experiments show that our method is effective comparing with traditional methods.
Measuring the connectivity of a cognitive radio ad-hoc network

In Cognitive Radio Ad-Hoc Networks (CRAHN) the behavior of the primary users influences the secondary network connectivity and the relevant performance. The methodologies used to evaluate network connectivity have to be worked up to take into account this aspect. In this letter we propose the use of Laplacian matrix and its second smallest eigenvalue to measure the network algebraic connectivity of a CRAHN. We re-elaborate the Laplacian matrix in order to have in its second smallest eigenvalue a function of the primary users behavior expressed as an activity factor. In this way we are able to monitor the algebraic connectivity of CRAHNs. This metric can be a useful instrument for network planning, data routing and network maintenance. Performance results show how this methodology can be efficiently applied in this kind of networks.
Semi-automatic registration of videos for improved watermark detection

Virtually every video watermarking technology can benefit from comparison with the original content. For non-blind schemes it is fundamental; for others it is an improvement to increase the watermark's signal-to-noise ratio by subtracting the content that is often noise to the detector. A direct frame-by-frame comparison of the videos is not possible due to the fact that illegal copies of videos usually differ significantly from their originals caused by different spatial resolution or frame rates, geometric distortions from capturing, or targeted attacks. In this paper, we present a software tool that enables the semi-automatic temporal and spatial synchronization of frames and pixels of two similar videos. This process is called registration. We put our focus on utilizing human capabilities with the smallest possible effort, to allow a high overall performance and precision of the registration. An efficient graphical user interface supports the users and visualizes the results of all steps. In addition, we specifically distinguish digitally reproduced copies from analog (camcorded) copies in which two or more frames are blended into a new frame.
Monoclonal antibody assay for detection of double-stranded RNA and application for detection of group A and non-group A rotaviruses

Fastidious viruses are generally detected in human body fluids by means of immunoassay or nucleic acid hybridization systems. These approaches can be difficult to apply to the detection of viruses which display variations in antigenic or genetic composition. Rotaviruses are examples of viruses which can display such variations. Recently identified antigenic variants, designated as non-group A rotaviruses, cannot be detected by immunoassays or nucleic acid hybridization assays which utilize reagents directed at group A rotavirus strains. The incomplete understanding of the extent of antigenic and genetic variation has inhibited the development of assay systems for all of the non-group A rotaviruses and has limited the study of their role in human disease. While rotaviruses display genetic variation, they all contain a genome which consists of double-stranded RNA. We utilized a monoclonal antibody to devise a sensitive assay for the measurement of double-stranded RNA and applied it to the detection of a wide range of rotaviruses. We found that the assay could detect double-stranded RNA from as few as 10 PFU of standard strains of group A rotaviruses. The assay system was also capable of detecting double-stranded RNA from several strains of group B rotaviruses isolated from calves, rats, and pigs at levels below those at which viral RNA could be visualized by means of polyacrylamide gel electrophoresis. When applied to the detection of double-stranded RNA in serial stools shed by rotavirus-infected children, the assay system was capable of detecting double-stranded RNA in samples in which antigen could not be detected by immunoassay. The specific nature of the double-stranded RNA detected by this assay system could be determined by the elution of the nucleic acids from the monoclonal antibody and the reaction of the RNA with specific nucleotide probes. The measurement of double-stranded RNA offers a potential method for the sensitive detection of a wide range of rotaviruses and other members of the family Reoviridae.
Distinguishing between Topical and Non-Topical Information Diffusion Mechanisms in Social Media

A number of recent studies of information diffusion in social media, both empirical and theoretical, have been inspired by viral propagation models derived from epidemiology. These studies model the propagation of memes, i.e., pieces of information, between users in a social network similarly to the way diseases spread in human society. Importantly, one would expect a meme to spread in a social network amongst the people who are interested in the topic of that meme. Yet, the importance of topicality for information diffusion has been less explored in the literature. Here, we study empirical data about two different types of memes (hashtags and URLs) spreading through the Twitter's online social network. For every meme, we infer its topics and for every user, we infer her topical interests. To analyze the impact of such topics on the propagation of memes, we introduce a novel theoretical framework of information diffusion. Our analysis identifies two distinct mechanisms, namely topical and non-topical, of information diffusion. The non-topical information diffusion resembles disease spreading as in simple contagion. In contrast, the topical information diffusion happens between users who are topically aligned with the information and has characteristics of omplex contagion. Non-topical memes spread broadly among all users and end up being relatively popular. Topical memes spread narrowly among users who have interests topically aligned with them and are diffused more readily after multiple exposures. Our results show that the topicality of memes and users' interests are essential for understanding and predicting information diffusion.
Dealing with EBV sero‐negative recipients: copy paste the CMV recipe? *

The main risk is the subsequent development of EBVrelated post-transplant lymphoproliferative disorder (PTLD). This association is well known but was recently re-examined by the Registry of Transplant Recipients in the United States. The analysis confirmed the higher risk of PTLD for D+/R) with adjusted hazard ratios up to 3.58 for kidney transplants [2]. In transplantation settings the lytic replication phase of EBV in epithelial cells is usually not the matter of concern but the latent infection of B cells. If the latent B cell infection takes place under immunosuppression, the development of a controlling immune response is impaired. It may lead to inadequate production of EBVspecific CD4 and CD8 T cells and open the way to uncontrolled B-cell replication. The latent EBV infection is characterized by the persistence of the viral genome in B cells and the expression of restricted latent gene products which can drive cell proliferation. The latent infected cells are furthermore protected
Kinetics of substrate recognition and cleavage by human 8-oxoguanine-DNA glycosylase

Human 8-oxoguanine-DNA glycosylase (hOgg1) excises 8-oxo-7,8-dihydroguanine (8-oxoG) from damaged DNA. We report a pre-steady-state kinetic analysis of hOgg1 mechanism using stopped-flow and enzyme fluorescence monitoring. The kinetic scheme for hOgg1 processing an 8-oxoG:C-containing substrate was found to include at least three fast equilibrium steps followed by two slow, irreversible steps and another equilibrium step. The second irreversible step was rate-limiting overall. By comparing data from Ogg1 intrinsic fluorescence traces and from accumulation of products of different types, the irreversible steps were attributed to two main chemical steps of the Ogg1-catalyzed reaction: cleavage of the N-glycosidic bond of the damaged nucleotide and β-elimination of its 3′-phosphate. The fast equilibrium steps were attributed to enzyme conformational changes during the recognition of 8-oxoG, and the final equilibrium, to binding of the reaction product by the enzyme. hOgg1 interacted with a substrate containing an aldehydic AP site very slowly, but the addition of 8-bromoguanine (8-BrG) greatly accelerated the reaction, which was best described by two initial equilibrium steps followed by one irreversible chemical step and a final product release equilibrium step. The irreversible step may correspond to β-elimination since it is the very step facilitated by 8-BrG.
IntroClassJava: A Benchmark of 297 Small and Buggy Java Programs

Reproducible and comparative research requires well-designed and publicly available benchmarks. We present IntroClassJava, a benchmark of 297 small Java programs, specified by Junit test cases, and usable by any fault localization or repair system for Java. The dataset is based on the IntroClass benchmark and is publicly available on Github.
Neural Embedding Language Models in Semantic Clustering of Web Search Results

In this paper, a new approach towards semantic clustering of the results of ambiguous search queries is presented. We propose using distributed vector representations of words trained with the help of prediction-based neural embedding models to detect senses of search queries and to cluster search engine results page according to these senses. The words from titles and snippets together with semantic relationships between them form a graph, which is further partitioned into components related to different query senses. This approach to search engine results clustering is evaluated against a new manually annotated evaluation data set of Russian search queries. We show that in the task of semantically clustering search results, prediction-based models slightly but stably outperform traditional count-based ones, with the same training corpora.
Characterization of the Relative Abundance of the Citrus Pathogen Ca. Liberibacter Asiaticus in the Microbiome of Its Insect Vector, Diaphorina citri, using High Throughput 16S rRNA Sequencing

The relationship between the causal agent of Huanglongbing (HLB), Ca. Liberibacter asiaticus(Las), and the naturally occurring endosymbiotic community of its insect vector, the Asian citrus psyllid (ACP), Diaphorina citri, was studied. Variation was observed in the titer of Las within an ACP population feeding on the same material. The cause of this disparity is unknown, and has implications for Las transmission and the spread of HLB. This study utilizes culture independent methods to establish the relationship between the ACP’s microbial community and Las acquisition. DNA from 21 psyllids was amplified using universal 16S rRNA primers with Illumina adaptor regions and a sample-specific 7- base identifier. These amplicons were then batch-sequenced on the Illumina platform. The resulting sequences were separated by the identifier, and compared to known sequences in a 16S rRNA database. The microbial communities of each psyllid were compared to determine whether a correlation exists between the ACP’s endosymbionts and level of Las acquisition. ACPs were dominated by the same four bacterialgenera regardless of the abundance of Ca.Liberibacter. A combination of qPCR and Illumina sequencing was used to establish an infection gradient among the sampled ACPs. The Ca. Liberibacter titer within the insect was found to have a strong negative relationship with an endosymbiont residing in the syncytium of the mycetocyte and a positive relationship with Wolbachia. These correlations have implications in the acquisition of Las by the ACP as well as the activities of Las within this vector.
Beyond-the-Desktop Interactive Visualizations

There are many established information visualizations on desktop computers that rely on a regular screen and the combination of mouse and keyboard as input devices. Mobile devices, however, are becoming more and more widespread. Also, tabletop computers may soon find their way into everyday life. Existing visualizations cannot be ported to these devices due to different screen sizes and input modalities. In this paper, nine exemplary interactive visualizations across different devices are discussed, covering three different areas: photo collections, maps and scatterplots. Then, four different criteria are applied to them. The examples are categorized by data type, screen size, input bandwidth and supported tasks and techniques to reduce screen clutter. The resulting classification leads to some discoveries concerning how the examples deal with the limitations and opportunities of new devices. Photo collection tools, for example, are forced to abandon their typical file browser interface on mobile devices. Maps, on the other hand, profit from innovative methods of input. Altogether, interactive visualizations on devices beyond the desktop have the potential to develop new input and output concepts that increase usability.
Eight Domains of Pet-Owner Wellness: Valuing the Owner-Pet Relationship in the Counseling Process

The purpose of the study was to explore the impact of pet ownership in order to identify domains of pet-owner wellness and to inform counselors of the value of exploring the owner-pet relationship with clients. A qualitative study was conducted using open-ended, semi-structured interviews. A consensual qualitative research approach was taken to analyze the data. Findings were organized into eight domains of pet-owner wellness impact: emotional and physical nurturance, sense of family, sense of responsibility and purpose, friendship or companionship, social interaction and connections, personal values and spiritual meaning, fun and play, and physical health. Although participants tended to discuss most pet-ownership impacts positively, some also cited negative impacts. Given the number of wellness areas that pet ownership can impact, counselors are encouraged to explore owner-pet relationships in the counseling process.
Distinct and Conserved Prominin-1/CD133–Positive Retinal Cell Populations Identified across Species

Besides being a marker of various somatic stem cells in mammals, prominin-1 (CD133) plays a role in maintaining the photoreceptor integrity since mutations in the PROM1 gene are linked with retinal degeneration. In spite of that, little information is available regarding its distribution in eyes of non-mammalian vertebrates endowed with high regenerative abilities. To address this subject, prominin-1 cognates were isolated from axolotl, zebrafish and chicken, and their retinal compartmentalization was investigated and compared to that of their mammalian orthologue. Interestingly, prominin-1 transcripts—except for the axolotl—were not strictly restricted to the outer nuclear layer (i.e., photoreceptor cells), but they also marked distinct subdivisions of the inner nuclear layer (INL). In zebrafish, where the prominin-1 gene is duplicated (i.e., prominin-1a and prominin-1b), a differential expression was noted for both paralogues within the INL being localized either to its vitreal or scleral subdivision, respectively. Interestingly, expression of prominin-1a within the former domain coincided with Pax-6–positive cells that are known to act as progenitors upon injury-induced retino-neurogenesis. A similar, but minute population of prominin-1–positive cells located at the vitreal side of the INL was also detected in developing and adult mice. In chicken, however, prominin-1–positive cells appeared to be aligned along the scleral side of the INL reminiscent of zebrafish prominin-1b. Taken together our data indicate that in addition to conserved expression of prominin-1 in photoreceptors, significant prominin-1–expressing non-photoreceptor retinal cell populations are present in the vertebrate eye that might represent potential sources of stem/progenitor cells for regenerative therapies.
Persuasive messages : the process of influence

List of Figures. List of Boxes. List of Tables. Preface. Part I: Attitudes and Persuasion: . 1. The Importance of Persuasion. 2. The Cognitive Approach to Persuasion. 3. The Source of Persuasive Messages: Credibility. 4. Ethical Concerns. Part II: Preparing Persuasive Communication: . 5. Purpose and Audience. 6. Organization: Structuring the Message. 7. Substance: Support for Your Ideas. 8. Symbols and Style. 9. Hostile, Apathetic, Motivated, and Multiple Audiences. Part III: Theories of Persuasion: . 10. Consistency Theories of Attitude Change. 11. Social Judgment/Involvement Theory. 12. Theory of Reasoned Action. Part IV: Critical Consumers of Persuasive Messages: . 13. Persuasion in Advertising. 14. Persuasion in Political Campaigns. References. Index