Miracle-dz/UniFAR-FTUs huggingface dataset:
Monetary Institutions, Partisanship, and Inflation Targeting

Since 1989, twenty-five countries have adopted a monetary policy rule known as inflation targeting (IT), in which the central bank commits to using monetary policy solely for the purpose of meeting a publicly announced numerical inflation target within a particular time frame. In contrast, many other countries continue to conduct monetary policy without a transparent nominal anchor. The emergence of IT has been almost completely ignored by political scientists, who instead have focused exclusively on central bank independence and fixed exchange rates as strategies for maintaining price stability. We construct a simple model that demonstrates that countries are more likely to adopt IT when there is a conformity of preferences for low-inflation monetary policy between the government and the central bank. More specifically, the combination of a right-leaning government and a central bank without bank regulatory authority is likely to be associated with the adoption of IT. Results from a spatial autoregressive probit model estimated on a time-series cross-sectional data set of seventy-eight countries between 1987 and 2003 provide strong statistical support for our argument. The model controls for international diffusion from neighboring countries by accounting for spatial dependence in the dependent variable, but our results indicate that domestic interests and institutions—rather than the influence of neighboring countries—drive the adoption of IT.We thank David Bearce, Bill Bernhard, Cristina Bodea, Lawrence Broz, Bill Clark, Nate Jensen, Phil Keefer, David Leblang, Eric Reinhardt, Shanker Satyanath, Jerome Vandenbussche, Robert Walker, Tom Willett, and the editors and anonymous reviewers for helpful comments and suggestions. We also thank Sergio Bejar and Jon Bischof for research assistance. Earlier versions of this article were presented at the first annual International Political Economy Society meeting, the 11th annual conference of the International Society for New Institutional Economics, and the 2007 annual meeting of the Midwest Political Science Association; we thank the conference participants for their feedback and suggestions. Mukherjee thanks the Niehaus Center for Globalization and Governance at Princeton University for research support.
Investigating the Role of F-Actin in Human Immunodeficiency Virus Assembly by Live-Cell Microscopy

ABSTRACT Human immunodeficiency virus type 1 (HIV-1) particles assemble at the plasma membrane, which is lined by a dense network of filamentous actin (F-actin). Large amounts of actin have been detected in HIV-1 virions, proposed to be incorporated by interactions with the nucleocapsid domain of the viral polyprotein Gag. Previous studies addressing the role of F-actin in HIV-1 particle formation using F-actin-interfering drugs did not yield consistent results. Filamentous structures pointing toward nascent HIV-1 budding sites, detected by cryo-electron tomography and atomic force microscopy, prompted us to revisit the role of F-actin in HIV-1 assembly by live-cell microscopy. HeLa cells coexpressing HIV-1 carrying fluorescently labeled Gag and a labeled F-actin-binding peptide were imaged by live-cell total internal reflection fluorescence microscopy (TIR-FM). Computational analysis of image series did not reveal characteristic patterns of F-actin in the vicinity of viral budding sites. Furthermore, no transient recruitment of F-actin during bud formation was detected by monitoring fluorescence intensity changes at nascent HIV-1 assembly sites. The chosen approach allowed us to measure the effect of F-actin-interfering drugs on the assembly of individual virions in parallel with monitoring changes in the F-actin network of the respective cell. Treatment of cells with latrunculin did not affect the efficiency and dynamics of Gag assembly under conditions resulting in the disruption of F-actin filaments. Normal assembly rates were also observed upon transient stabilization of F-actin by short-term treatment with jasplakinolide. Taken together, these findings indicate that actin filament dynamics are dispensable for HIV-1 Gag assembly at the plasma membrane of HeLa cells. IMPORTANCE HIV-1 particles assemble at the plasma membrane of virus-producing cells. This membrane is lined by a dense network of actin filaments that might either present a physical obstacle to the formation of virus particles or generate force promoting the assembly process. Drug-mediated interference with the actin cytoskeleton showed different results for the formation of retroviral particles in different studies, likely due to general effects on the cell upon prolonged drug treatment. Here, we characterized the effect of actin-interfering compounds on the HIV-1 assembly process by direct observation of virus formation in live cells, which allowed us to measure assembly rate constants directly upon drug addition. Virus assembly proceeded with normal rates when actin filaments were either disrupted or stabilized. Taken together with the absence of characteristic actin filament patterns at viral budding sites in our analyses, this indicates that the actin network is dispensable for HIV-1 assembly.
Trap-based positron beams

Large numbers of positrons can be accumulated and cooled in a Penning-type trap. These positron clouds can be manipulated and conditioned using plasma physics techniques, before being released from the trap to form high quality positron beams. These techniques offer a qualitatively new method for positron beam formation and manipulation that has significant advantages in efficiency, flexibility, and cost over current beam conditioning techniques. Unique capabilities include the production of ultracold beams, brightness enhancement by radial compression of the plasma prior to extraction, and simple implementation of harmonic potential bunching. # 2002 Elsevier Science B.V. All rights reserved.
A Randomized, Head-to-Head Study of Virtual Reality Exposure Therapy for Posttraumatic Stress Disorder

Virtual reality exposure therapy (VRET) is one of the few interventions supported by randomized controlled trials for the treatment of combat-related posttraumatic stress disorder (PTSD) in active duty service members. A comparative effectiveness study was conducted to determine if virtual reality technology itself improved outcomes, or if similar results could be achieved with a control exposure therapy (CET) condition. Service members with combat-related PTSD were randomly selected to receive nine weeks of VRET or CET. Assessors, but not therapists, were blinded. PTSD symptom improvement was assessed one week and 3 months after the conclusion of treatment using the clinician-administered PTSD scale (CAPS). A small crossover component was included. Results demonstrated that PTSD symptoms improved with both treatments, but there were no statistically significant differences between groups. Dropout rates were higher in VRET. Of those who received VRET, 13/42 (31%) showed >30% improvement on the CAPS, versus 16/43 (37%) who received CET. Three months after treatment, >30% improvement was seen in 10/33 (30%) of VRET participants and 12/33 (36%) in CET. Participants who crossed over (n = 11) showed no statistically significant improvements in a second round of treatment, regardless of condition. This study supported the utility of exposure therapy for PTSD, but did not support additional benefit by the inclusion of virtual reality.
Acitretin systemic and retinoic acid 0.1% cream supression of basal cell carcinoma

Retinoids have been used for years as monotherapy and/or in combination for treatment and suppression of cutaneous malignancies in patients with basal cell nevus syndrome, xeroderma pigmentosum, or cutaneous T-cell lymphoma (CTCL) basal cell carcinoma (BCC). We report 4 cases with BCC confirmed by histopathology who were treated by short-term systemic acitretin combined with retinoic acid 0.1% cream. The 4 cases with BCC showed good response to the treatment without severe adverse effects during treatment and follow-up. The finding suggests that acitretin may be an appropriate treatment option for elderly patients who require less invasive treatment for BCC.
N-[2-(2-Chlorophenyl)-2-hydroxyethyl]propan-2-aminium benzoate

In the title compound, C11H17ClNO+·C7H5O2 −, obtained by the reaction of chlorprenaline {or 1-(2-chlorophenyl)-2-[(1-methylethyl)amino]ethanol} and benzoic acid, the chlorprenaline is twisted moderately [C—C—C—C torsion angle = −76.00 (17)°] compared with related compounds. The molecules as usual form dimers. In the crystal structure, the two components are connected by classical O—H⋯O and N—H⋯O hydrogen bonds.
Morphological response contributes to patient selection for rescue liver resection in chemotherapy patients with initially un-resectable colorectal liver metastasis

Morphological response is considered an improved surrogate to the Response Evaluation Criteria in Solid Tumors (RECIST) model with regard to predicting the prognosis for patients with colorectal liver metastases. However, its use as a decision-making tool for surgical intervention has not been examined. The present study assessed the morphological response in 50 patients who underwent chemotherapy with or without bevacizumab for initially un-resectable colorectal liver metastases. Changes in tumor morphology between heterogeneous with uncertain borders and homogeneous with clear borders were defined as an optimal response (OR). Patients were also assessed as having an incomplete response (IR), and an absence of marked changes was assessed as no response (NR). No significant difference was observed in progression-free survival (PFS) between complete response/partial response (CR/PR) and stable disease/progressive disease (SD/PD), according to RECIST. By contrast, PFS for OR/IR patients was significantly improved compared with that for NR patients (13.2 vs. 8.7 months; P=0.0426). Exclusion of PD enhanced the difference in PFS between OR/IR and NR patients (15.1 vs. 9.3 months; P<0.0001), whereas no difference was observed between CR/PR and SD. The rate of OR and IR in patients treated with bevacizumab was 47.4% (9/19), but only 19.4% (6/31) for patients that were not administered bevacizumab. Comparison of the survival curves between OR/IR and NR patients revealed similar survival rates at 6 months after chemotherapy, but the groups exhibited different survival rates subsequent to this period of time. Patients showing OR/IR within 6 months appeared to be oncologically stable and could be considered as candidates for surgical intervention, including rescue liver resection. Comparing the pathological and morphological features of the tumor with representative optimal response, living tumor cells were revealed to be distributed within the area of vascular reconstruction induced by bevacizumab, resulting in a predictive value for prognosis in the patients treated with bevacizumab. The present findings provided the evidence for physicians to consider patients with previously un-resectable metastatic colorectal cancer as candidates for surgical treatment. Morphological response is a useful decision-making tool for evaluating these patients for rescue liver resection following chemotherapy.
Short-term effects of a non-dieting lifestyle intervention program on weight management, fitness, metabolic risk, and psychological well-being in obese premenopausal females with the metabolic syndrome.

Lifestyle modification has been widely acknowledged as the primary treatment for the metabolic syndrome (MetS). We examined the short-term effects of a non-dieting lifestyle intervention program, within the theoretical psychological framework of self-determination theory (SDT), on metabolic fitness and psychological well-being among premenopausal, clinically obese women. A secondary analysis of a randomized, controlled, 3 month, intensive, community-based lifestyle intervention study was performed on 31 pre-menopausal obese women with the MetS (56.4% of original study sample). These participants had been randomly allocated to a non-dieting lifestyle intervention group (n = 17) or waiting list control (n = 14). Among participants who completed repeat anthropometric and cardiorespiratory fitness measurements after 3 months intervention, the lifestyle intervention group showed a significant improvement in VO2 (mL.kg(-1). min(-1)) compared with control (test for interaction, p = 0.003). No significant difference was found for body mass. Metabolic improvements were evident for diastolic blood pressure and high-density lipoprotein cholesterol in both groups. The lifestyle intervention group also showed significantly improved general psychological well-being compared with the control group (test for interaction, p = 0.0005). All of the psychological well-being subscales showed significant favourable changes in the intervention group as compared with controls. This short-term, non-dieting lifestyle intervention, consistent with the "Health at Every Size" (HAES) obesity treatment paradigm, significantly improved cardiorespiratory fitness and psychological well-being. Metabolic risk tended to improve after 3 months intervention with no significant difference in the resolution of the MetS between intervention and control participants.
Hartsfield syndrome associated with a novel heterozygous missense mutation in FGFR1 and incorporating tumoral calcinosis

Hartsfield Syndrome Associated with a Novel Heterozygous Missense Mutation in FGFR1 and Incorporating Tumoral Calcinosis Rathi Prasad, Carole Brewer, and Christine P. Burren* Department of Paediatric Endocrinology, Bristol Royal Hospital for Children, University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom Department of Clinical Genetics, Royal Devon & Exeter Hospital, Exeter, United Kingdom
A Comparison of Earnings Management between Kse Firms and Kosdaq Firms

This study investigates differences in earnings management practices of Korea Stock Exchange (KSE) firms and KOSDAQ (a Korean version of the NASDAQ market) firms during the period of 1996-1997. A sample of 1,256 KSE and 577 KOSDAQ firm-year observations is used to compare earnings management practices of firms listed in the two different stock exchanges. The results of the study reveal that KOSDAQ firms tend to more actively manipulate earnings to avoid losses than KSE firms. KOSDAQ firms generally tend to increase reported earnings more aggressively than KSE firms when their operating cash flows are poor, and play down their reported earnings more when their operating cash flows are exceptionally good. The results of the study are quite robust in the sense that more aggressive earnings management practices of KOSDAQ firms persist even when operating cash flows are controlled. Copyright Blackwell Publishers Ltd, 2005.
Heimlich's maneuver-assisted bronchoscopic removal of airway foreign body

Aspiration of foreign bodies (FBs) by children can lead to serious illness and sometimes even death. Bronchoscopic removal of the FB is necessary to prevent from any catastrophic event. Sometimes bronchoscopic removal is not possible due to the larger size of the FB, sharp FB, or long duration FB. Tracheostomy is normally used for the removal of such FBs. The aim of this case report is to highlight the use of Heimlich maneuver for the removal of such FBs before opting invasive procedures. In the present case, a 5-year-old child was presented with history of FB aspiration 5 h back. After multiple failed bronchoscopic attempts to remove the FB it was decided to use Heimlich maneuver in the supine position. A single attempt of Heimlich maneuver expelled the FB into the oral cavity, which was removed by Magill's forceps. On repeated bronchoscope check, there was no remnant of FB. Child's further course of stay in hospital was uneventful. In conclusion, Heimlich maneuver may be useful in patient with failed bronchoscope removal of airway FBs before proceeding for tracheotomy or other invasive procedures.
An Intercountry Comparison of Agricultural Production Efficiency

Intercountry cross-section comparison of total productivity in agriculture showed that differences in production efficiency were small relative to differences in labor productivity among countries at a same stage of economic development but very large among different stages of development. Moreover, the large differences in total productivity between the developed and the less developed countries widened further during the past two decades. The results suggest a hypothesis that agriculture in the less developed countries as a whole has not yet entered the phase of "modern economic growth" a la Kuznets.
Economic Restructuring and Total Factor Productivity Growth: Tunisia Over the Period 1983-2001

In this paper we aim to measure and decompose the growth of frontier total factor productivity (TFP) in Tunisia over the period 1983-2001. We define frontier TFP growth as the shift of the economy’s production frontier, which we obtain by solving for each year a linear program, a sort of aggregate DEA analysis. We then decompose this aggregate frontier TFP growth into changes in technology, terms of trade, efficiency and resource utilization. We can also attribute frontier TFP growth to its main beneficiaries: labor, decomposed into five types, capital, decomposed into two types, and the allowable trade deficit.We find that frontier TFP grew by about 1% a year after the introduction of the structural adjustment program of 1987. Labor, in particular unskilled labor, was the main beneficiary of frontier TFP growth. The Solow residual reflecting technological change was the main driver of frontier TFP growth. The terms of trade were not favorable to Tunisia. After 1992, while the Tunisian efficiency frontier moved outwards, the country moved away from its efficiency frontier.
The Economic Position of Women in Asia

This article surveys the literature on the economic position of women in Asian countries. Statistics show that the relative position of women improves with economic development. A negative income effect on women's economic participation in the paid workforce results in an inverse U‐shaped relationship between female participation rate and economic development. Cultural influences affect the degree of discrimination against women, and these vary between countries. China and Australia illustrate the potentially moderating role of government policy on gender discrimination.
Youth leadership training in Hong Kong: current developments and the way ahead

This study explicates the intervention goals, domains and strategies of youth leadership training programmes in Hong Kong using data collected on the Internet. The results show that youth leadership training programmes in Hong Kong are designed and organised to achieve five goals: (1) helping young people to achieve positive development and cultivate their leadership potential, (2) enhancing the ability of young people to form interpersonal relationships and engage in team-building, (3) encouraging young people to participate in community affairs and social services, (4) fostering a national identity and a deeper understanding of the mother country and (5) equipping young people with an international outlook. These goals are achieved through five inter-related training domains, including the personal, interpersonal, community, national and international domains. The intervention strategies currently used in these programmes comprise experiential learning, adventure-based training, service learning, non-local exposure and project-based competition strategies. The characteristics of the leadership training programmes and their implications for the future development of policy and practice in Hong Kong are also discussed.
4Pi-confocal microscopy provides three-dimensional images of the microtubule network with 100- to 150-nm resolution.

We show the applicability of 4Pi-confocal microscopy to three-dimensional imaging of the microtubule network in a fixed mouse fibroblast cell. Comparison with two-photon confocal resolution reveals a fourfold better axial resolution in the 4Pi-confocal case. By combining 4Pi-confocal microscopy with Richardson-Lucy image restoration a further resolution increase is achieved. Featuring a three-dimensional resolution in the range 100-150 nm, the 4Pi-confocal (restored) images are intrinsically more detailed than their confocal counterparts. Our images constitute what to our knowledge are the best-resolved three-dimensional images of entangled cellular microtubules obtained with light to date.
Impact assessment: Seeing the wood and the trees

This paper summarises the results of a joint action-research project undertaken by a number of international and local NGOs, which involved case studies in four countries in Africa, three in South Asia, one in Latin America, and one in the UK. The paper seeks to situate the discussion of impact assessment in the context of a growing critique of international NGOs. Overall, it is suggested that simple models of cause and effect which link project inputs to outputs and impact, although important, are usually inadequate for assessing the impact of what NGOs do. Instead, the author recommends the need to develop models that embrace the wider context of influences and change processes that surrounds projects and programmes, and the broad-ranging impacts that result. A major conclusion to emerge from the case studies is that the ability to select a judicious mix, and sequence, of tools and methods for impact assessment is vital. The paper concludes by looking at the broader policy implications of the studies notably in relation to: dealing with the problems of attribution and aggregation; exploring the issue of poverty reach and gender relations; warning against simplistic use of impact assessment to allocate resources; and in suggesting how impact assessment can be part of a 'virtuous circle' of change that can help promote greater accountability and learning among international NGOs.