Miracle-dz/UniFAR-FTUs huggingface dataset:
Conception d'élements passifs magnétiques pour convertisseurs de faible puissance

Cette these se place dans le contexte d'alimentation des systemes electroniques nomades fonctionnant sous faible tension et faible courant. Dans ce cadre, de nombreuses equipes travaillent depuis plus de trente ans sur le probleme de l'integration de composants magnetiques sur silicium. L'objectif aujourd'hui est de realiser une inductance de 1µH capable de supporter 1W avec des tensions de l'ordre du volt, dans une gamme de frequence allant de 1MHz a 10MHz. L'etude des phenomenes physiques lies au caractere inductif et resistif de spirales planaires a abouti a la mise en place d'outils d'etude numerique permettant d'analyser les spirales classiques ainsi que l'association d'inductances magnetiquement couplees dans le but de diminuer leur resistance. Ensuite, les travaux ont portes sur le developpement d'un procede technologique base sur les techniques MEMS. Finalement, un banc de caracterisation impedance metrique a egalement ete concu afin de determiner les limites du fonctionnement frequentiel des composants realises.
The Urgency of Principle of Good Governance in Environmental Protection and Management: Case Study of Sepat Reservoir Surabaya

Transfer of Land Functions in Indonesia increasingly shows a graph of rapid increase even uncontrolled, mainly in the conversion of agricultural land into residential land. Increased settlement needs are based on an increase in the population of an area, as happened in the city of Surabaya, the conversion of functions becomes one of the steps to meet the primary needs of the community, namely settlements. In addition, the need for public facilities to meet the secondary needs of the community, however, land conversion is always the origin of environmental damage. Therefore this study aims to find out and analyze the consequences of the conversion of the sepat reservoir area involving the Surabaya City government with the company PT. CS became a luxury housing area and made the sepat reservoir as part of its yard, which had an impact on the closure of the sepat reservoir. This study uses empirical legal research methods and uses a case approach method. The results of this study indicate that there are legal implications of the lack of transparency in the public administration documents of the sepat reservoir, fearing that it would lead to a bad precedent for the administration of government in the city of Surabaya. Implementation of good governance principles by opening the sepat reservoir public administration document in order to provide a sense of security and foster the trust of the Surabaya City residents to the Government. The result of the study after the analysis was found there was an omission by the Surabaya city government on the sepat reservoir case, considering that there had been a civil agreement to exchange the sepat reservoir with the Gelora Bung Tomo (GBT) land which had been going on for a long time and if the government made unilateral blocking then it would civil disputes arose between Surabaya city government and PT.CS. Keywords—Good Governance; Environmental; Spatial
Linkages between Organization Climate and Work Outcomes: Perceptual Differences among Health Service Professionals as a Function of Customer Contact Intensity

The delivery of high-quality service, rendered by health service professionals who interact with customers (patients), increases the likelihood that customers will form positive evaluations of the quality of their service encounters as well as high levels of customer satisfaction. Using linkage theory to develop our conceptual framework, we identify four clusters of variables which contribute to a chain of sequential events that connect organization climate to personal and operational work outcomes. We then examine the perceptual differences of service professionals, grouped by intensity of customer contact, with respect to these variables. National data for this project were obtained from multiple sources made available by the Veterans Healthcare Administration (VHA). Cross-group differences were tested using a series of variance analyses. the results indicate that level of customer-contact intensity plays a significant role in explaining variation in perceptions of support staff, clinical practitioners, and nurses at the multivariate and univariate levels of analysis. Contact intensity appears to be a core determinant of the nature of work performed by health service professionals as well as their psychological responses to organizational and customer-related dynamics. Health service professionals are important resources because of their specialized knowledge, labor expense, and scarcity. Based on findings from our research, managers are advised to survey employees’ perceptions of their organizational environment and design practices that respond to the unique viewpoints of each of the professional groups identified in this study. Such tailoring should help executives maximize the value of investments in human resources by underwriting patient satisfaction and financial sustainability.
Nature of Contrast and Coarticulation: Evidence from Mizo Tones and Assamese Vowel Harmony

Tonal coarticulation is universally found to be greater in extent in the carryover direction compared to the anticipatory direction ([1], [2], [3], [4], [5]) leading to assimilatory processes. In general, carryover coarticulation has been understood to be due to intertio-mechanical forces, and, anticipatory effects are seen to be a consequence of parallel activation of articulatory plans ([6]). In this paper, we report on results from a set of Artificial Neural Networks (ANN) trained to predict adjacent tones in disyllabic sequences. Our results confirm the universal pattern of greater carryover effects in Mizo leading to tonal assimilation. In addition, we report on results from single-layered ANNmodels and Support VectorMachines (SVM) that predict the identity of V2 from V1 (anticipatory) consistently better than V1 from V2 (carryover) in Assamese non-harmonic #. V1CV2. # sequences. The directionality in the performance of the V1 and V2 models, help us conclude that the directionality effect of coarticulation in Assamese non-harmonic sequences is greater in the anticipatory direction, which is the same direction as in the harmonic sequences. We argue that coarticulatory propensity exhibits a great deal of sensitivity to the nature of contrast in a language.
Replication-Competent Recombinant Vesicular Stomatitis Virus Encoding Hepatitis C Virus Envelope Proteins

ABSTRACT Although in vitro replication of the hepatitis C virus (HCV) JFH1 clone of genotype 2a (HCVcc) has been developed, a robust cell culture system for the 1a and 1b genotypes, which are the most prevalent viruses in the world and resistant to interferon therapy, has not yet been established. As a surrogate virus system, pseudotype viruses transiently bearing HCV envelope proteins based on the vesicular stomatitis virus (VSV) and retrovirus have been developed. Here, we have developed a replication-competent recombinant VSV with a genome encoding unmodified HCV E1 and E2 proteins in place of the VSV envelope protein (HCVrv) in human cell lines. HCVrv and a pseudotype VSV bearing the unmodified HCV envelope proteins (HCVpv) generated in 293T or Huh7 cells exhibited high infectivity in Huh7 cells. Generation of infectious HCVrv was limited in some cell lines examined. Furthermore, HCVrv but not HCVpv was able to propagate and form foci in Huh7 cells. The infection of Huh7 cells with HCVpv and HCVrv was neutralized by anti-hCD81 and anti-E2 antibodies and by sera from chronic HCV patients. The infectivity of HCVrv was inhibited by an endoplasmic reticulum α-glucosidase inhibitor, N-(n-nonyl) deoxynojirimycin (Nn-DNJ), but not by a Golgi mannosidase inhibitor, deoxymannojirimycin. Focus formation of HCVrv in Huh7 cells was impaired by Nn-DNJ treatment. These results indicate that the HCVrv developed in this study can be used to study HCV envelope proteins with respect to not only the biological functions in the entry process but also their maturation step.
The cost effectiveness of combination antiretroviral therapy for HIV disease.

BACKGROUND Combination antiretroviral therapy with a combination of three or more drugs has become the standard of care for patients with human immunodeficiency virus (HIV) infection in the United States. We estimated the clinical benefits and cost effectiveness of three-drug antiretroviral regimens. METHODS We developed a mathematical simulation model of HIV disease, using the CD4 cell count and HIV RNA level as predictors of the progression of disease. Outcome measures included life expectancy, life expectancy adjusted for the quality of life, lifetime direct medical costs, and cost effectiveness in dollars per quality-adjusted year of life gained. Clinical data were derived from major clinical trials, including the AIDS Clinical Trials Group 320 Study. Data on costs were based on the national AIDS Cost and Services Utilization Survey, with drug costs obtained from the Red Book. RESULTS For patients similar to those in the AIDS Clinical Trials Group 320 Study (mean CD4 cell count, 87 per cubic millimeter), life expectancy adjusted for the quality of life increased from 1.53 to 2.91 years, and per-person lifetime costs increased from $45,460 to $77,300 with three-drug therapy as compared with no therapy. The incremental cost per quality-adjusted year of life gained, as compared with no therapy, was $23,000. On the basis of additional data from other major studies, the cost-effectiveness ratio for three-drug therapy ranged from $13,000 to $23,000 per quality-adjusted year of life gained. The initial CD4 cell count and drug costs were the most important determinants of costs, clinical benefits, and cost effectiveness. CONCLUSIONS Treatment of HIV infection with a combination of three antiretroviral drugs is a cost-effective use of resources.
Experiment on automatic functional requirements analysis with the EFRF's semantic cases

Software requirements analysis is crucial for any software project and it is the basis of requirements reuse within Software Product Line engineering. Software requirements specifications are usually expressed in natural language, which are informal, imprecise and ambiguous, thus analyzing them automatically is a challenging task. Although methods towards automatic analysis of software requirements have been studied before, many of them have limitations and effective researches in this area are still lacking. Therefore, in this paper a new approach was proposed to automatically extract structured information of functional requirements from Software Requirements Specifications in natural language. The methods of machine learning, natural language processing and semantic analysis were employed and combined in this approach. With a 10-fold cross validation setting, the method was evaluated on a manually annotated corpus. The experiments show that this approach achieves a good performance. Moreover, it was found that the model trained on the requirements dataset of the E-commerce systems, can be used to extract semantic information from the requirements of auto-maker systems. The cross-domain extraction results show that the method of this paper is domain independent and robust to some extent.
Assignment1 of the NR2E3 gene to mouse chromosome 9 and to human chromosome 15q22.33→q23

Supported by grants from the Danish Biotechnological Research and Development Program 1996–1998, the Danish Cancer Society, the Danish Research Center for Growth and Regeneration, the Danish Research Council, Novo Nordisk Foundation, Åge Bangs Foundation, the German Genome Program/Deutsche Forschungsanstalt für Luftund Raumfahrt e. V. (Grant No. 4763), the EU-Commission (BMH4-CT97-2268), and the Danish Environmental Research Program.
Intelligent fuzzy controller for lateral control of aircraft models

In this paper an intelligent control design methodology is presented for the design of controller for commercial aircrafts operating under abnormal flight conditions. The intelligent methodology is fuzzy logic based reference model control. Therefore, an intelligent fuzzy controller is designed and used as control system to meet transient requirements determined by a desired reference model. A generic transport model (GTM) of commercial aircrafts was used to extract a linearized latitudinal dynamic model and it was utilized for testing the effectiveness of the developed intelligent fuzzy controller. A baseline reference controller is used for performance comparison of the intelligent fuzzy controller. First, a fuzzy based controller was developed to track and control a specified state(s) of the aircraft and then its performance is compared with a baseline nominal reference controller. The testing was conducted under two scenarios: 1) Nominal flight conditions to control the yaw movement of the aircraft and 2) A stall failure on the rudder flight surface. The fuzzy controller was designed and interfaced with the aircraft's aileron and rudder to observe its effectiveness in controlling the lateral movement of the aircraft. The controller was designed based off linearized model of the aircraft to simplify the design process and track the stability of the developed controller. The results obtained from testing of the intelligent fuzzy controller produced desirable performance. The performance of the intelligent fuzzy controller was superior to that produced by the baseline controller. However, the time needed to completely identify and maintain the abnormal state was less than the desired time. Overall, the performance of the intelligent fuzzy controller was superior to that produced by the baseline controller. Details of the design process and the test results of the developed intelligent fuzzy control are report in this paper.
A simple score for estimating the long-term risk of fracture in patients using oral glucocorticoids.

BACKGROUND Previous analyses of risk factors for glucocorticoid (GC)-induced osteoporosis have focused on the estimation of relative rather than absolute fracture probability. AIM To estimate risk scores for the individual probability of fracture in GC users. DESIGN Retrospective data analysis. METHODS We evaluated all patients aged 40 years or older with a prescription for oral GCs in the General Practice Research Database (GPRD), which comprises the computerized medical records of around 7 million UK subjects. Individual risk factors for osteoporotic fractures were identified, and combined in a predictive model for 10-year absolute fracture risk. RESULTS Of 191 752 oral GC users aged > or =40 years, 7412 experienced an osteoporotic fracture. Several characteristics independently contributed to the fracture risk score (GC therapy, age, gender, fall history, fracture history, body mass index, smoking, previous diagnoses, use of medication, recent hospitalization and indication for GC treatment). Scores of 30, 40 and 50 corresponded to absolute 5-year fracture risks of 6.2%, 15.3% and 35.2%, respectively. A woman aged 65 years with RA, low BMI, and a previous history of fracture and falls, who used 15 mg GC daily (total risk score 54) would have a 5-year fracture risk of 47% (a man with similar history, 30.1%). Short-term use of high-dose GC therapy (> or =30 mg) was associated with only a small increased risk of osteoporotic fracture (RR 1.21, 95%CI 1.04-1.42) in patients with a history of GC use. DISCUSSION This risk score helps to predict an individual's risk of fracture during GC use. Decisions about bone protection treatment could be based on long-term risks of fracture.
Twin heart with a fused atria and separate ventricles in conjoined twins

One of the most interesting congenital malformations is that of conjoined twins. We report echocardiographic features of twin heart in dicephalus, tribrachius, dispinous, thoracoomphalopagus twin. It showed two hearts fused at atrial level. Right-sided heart had single atrial chamber with a single ventricle. A single great vessel, aorta, originated from it. Left-sided heart was well developed with two atria and two ventricles. There was a small mid muscular ventricular septal defect and a small patent ductus arteriosus. Great arteries had normal origins.
Task‐dependent modulation of 15‐30 Hz coherence between rectified EMGs from human hand and forearm muscles

1 Recent reports have shown task‐related changes in oscillatory activity in the 15‐30 Hz range in the sensorimotor cortex of human subjects and monkeys during skilled hand movements. In the monkey these oscillations have been shown to be coherent with oscillatory activity in the electromyographic activity of hand and forearm muscles. 2 In this study we investigated the modulation of oscillations in the electromyogram (EMG) of human volunteers during tasks requiring precision grip of two spring‐loaded levers. 3 Two tasks were investigated: in the ‘hold’ task, subjects were required to maintain a steady grip force (ca 2·1 N or 2·6 N) for 8 s. In the ‘ramp’ task, there was an initial hold period for 3 s (force ca 2·1 N) followed by a linear increase in grip force over a 2 s period. The task ended with a further steady hold for 3 s at the higher force level (ca 2·6 N). 4 Surface EMGs were recorded from five hand and forearm muscles in 12 subjects. The coherence of oscillatory activity was calculated between each muscle pair. Frequencies between 1 and 100 Hz were analysed. 5 Each subject showed a peak in the coherence spectra in the 15‐30 Hz bandwidth during the hold task. This coherence was absent during the initial movement of the levers. During the ramp task the coherence in the 15‐30 Hz range was also significantly reduced during the movement phase, and significantly increased during the second hold period, relative to the initial hold. 6 There was coherence between the simultaneously recorded magnetoencephalogram (MEG) and EMG during steady grip in the hold task; this coherence disappeared during the initial lever movement. Using a single equivalent current dipole source model, the coherent cortical activity was localized to the hand region of the contralateral motor cortex. This suggests that the EMG‐EMG coherence was, therefore, at least in part, of cortical origin. 7 The results are discussed in terms of a possible role for synchrony in the efficient recruitment of motor units during maintained grip.
Induction of Experimental Arthritis in Balb/C Mice by Inclusion of a Foreign Protein in the Collagen Inoculum

The susceptibility of mice to collagen‐induced arthritis (CIA) has, among other things, been linked to the major histocompatibility complex class II genes as well as other genes. This study was designed to examine the possibilities to establish CIA in low susceptible I‐Ad (Balb/C) mice. Balb/C mice were immunized twice with bovine type II collagen (BCII) in complete Freund’s adjuvant (CFA) containing the amount of Mycobacterium tuberculosis needed to induce CIA in low susceptible I‐Ab (C57BL/6) mice. Some mice received the conceivable arthritogenic inoculum mixed with ovalbumin (OVA). Clinical arthritis was monitored. Antibody activity and T‐cell reactivity to BCII were determined. Unexpectedly, only mice that were immunized with the BCII–OVA mixture developed arthritis. Combining BCII with another foreign protein, keyhole limpet hemocyanin, but not the self‐protein mouse serum albumin, also triggered arthritis. Prior to the appearance of arthritis the serum levels of IgG autoantibodies to BCII were higher in the coimmunized mice than in the mice that were immunized with BCII alone. Yet, splenocytes stimulated in vitro with BCII did not proliferate or produce interferon‐γ. Immunization of Balb/c mice with an emulsion‐containing CFA and BCII mixed with a foreign body, but not a self‐protein, elevates the level of circulating autoantibodies to CII and subsequently induces arthritis.
Boundary conditions for the emergence of relational trust among exporters and importers

Purpose This study looks to the answer of whether importers and exporters can develop relational trust and minimize the monitoring and control costs used to prevent opportunistic behavior in a trust relationship. Despite increasing scholarly interest in calculative and relational trust, the boundary conditions affecting the transformation of calculative trust into relational trust remain unaddressed. In response, this study aims to investigate the boundary conditions for the emergence of relational trust in inter-organizational relationships between Chinese exporters and Turkish importers. Design/methodology/approach Data were collected from Turkish SMEs that import from China. To measure trust between parties, semi-structured interviews with top managers and/or decision-making company owners were conducted. Interview questions covered three categories: antecedents of trust, ways of developing trust and outcomes of trust. Findings Results indicated that inter-organizational relationships between Chinese and Turkish firms lack relational-based trust. Most trade transactions between two parties are based on calculations of profit/loss, and Turkish firms use intermediary mechanisms to overcome lack of trust in this environment. The most important boundary conditions for the emergence of relational trust are behavioral uncertainty, the opportunistic behavior of Chinese suppliers and language and cultural barriers. Originality/value This study contributes to the existing literature by addressing the hitherto unaddressed question of what the boundary conditions are for the transformation of calculative trust into relational trust.
Comparison of the efficacy of local therapies for localized prostate cancer in the prostate-specific antigen era: a large single-institution experience with radical prostatectomy and external-beam radiotherapy.

PURPOSE To review biochemical relapse-free survival (bRFS) rates after either external-beam radiotherapy (RT) or radical prostatectomy (RP) for localized prostate cancer. PATIENTS AND METHODS All 1,682 patients had pretreatment prostate-specific antigen (PSA) levels and biopsy Gleason scores (bGS) assigned. No adjuvant therapy was administered after local treatment. RP was the treatment in 1,054 patients (63%) and RT in 628 patients (37%). Median follow-up was 51 months (range, 1 to 134). The median follow-up for RP versus RT patients was 50.5 v 51.0 months. Biochemical relapse was considered detectable PSA levels (> 0.2 ng/mL) in RP patients and three consecutive rising PSA levels in RT patients. The analysis was repeated with a more stringent definition of biochemical control after either RP or RT-namely, reaching and maintaining a PSA level < or = 0.5 ng/mL-and excluding patients receiving any androgen deprivation (AD). RESULTS Eight-year bRFS rates for RP versus RT were 72% and 70%, respectively (P =.010). Multivariate analysis indicated T stage (P <.001), pretreatment PSA (P <.001), bGS (P <.001), year of therapy (P <.001), and neoadjuvant AD (P =.019) to be the only independent predictors of relapse. Age (P =.78), race (P =.29), prior transurethral resection of prostate (P =.81), and treatment modality (P =.96) were not independent predictors of treatment failure. Fifty-one percent of RP patients had favorable tumors (T1 to T2A, pretreatment PSA < or = 10 ng/mL, bGS < or = 7), compared with only 34% of RT patients (P <.001). Repeat analysis with a stringent definition of biochemical failure and excluding patients receiving AD indicated no impact of treatment modality on outcome. CONCLUSION Eight-year biochemical failure rates were identical between RT and RP in any subgroup. Outcome is determined mainly by pretreatment PSA levels, bGS, clinical T stage, and, for RT patients, radiation dose.