Miracle-dz/UniFAR-FTUs huggingface dataset:
Development/plasticity/repair Camp Response Element-binding Protein Regulates Differentiation and Survival of Newborn Neurons in the Olfactory Bulb

The transcription factor cAMP response element-binding protein (CREB) is involved in multiple aspects of neuronal development and plasticity. Here, we demonstrate that CREB regulates specific phases of adult neurogenesis in the subventricular zone/olfactory bulb (SVZ/OB) system. Combining immunohistochemistry with bromodeoxyuridine treatments, cell tracer injections, cell transplants, and quantitative analyses, we show that although CREB is expressed by the SVZ neuroblasts throughout the neurogenic process, its phos-phorylation is transient and parallels neuronal differentiation, increasing during the late phase of tangential migration and decreasing after dendrite elongation and spine formation. In vitro, inhibition of CREB function impairs morphological differentiation of SVZ-derived neuroblasts. Transgenic mice lacking CREB, in a null CREM genetic background, show reduced survival of newborn neurons in the OB. This finding is further supported by peripheral afferent denervation experiments resulting in downregulation of CREB phosphor-ylation in neuroblasts, the survival of which appears heavily impaired. Together, these findings provide evidence that CREB regulates differentiation and survival of newborn neurons in the OB.
Mining Documents in a Small Enterprise Using WordStat

Text mining is growing as an essential method of knowledge discovery from general and business documents. Although, documents viz. press releases, emails, memos, contracts, government reports and news feeds, are considered to be unstructured, they are tapped for information using text analysis techniques like feature extraction, thematic indexing, clustering and summarization. For this project, 30 representative documents from a small enterprise were collected to determine the dominant features in their activities. Based on the analysis of the document profiles generated by extracting the frequencies of certain terms, clustering and filtering on the basis of both repetitive occurrence and co-occurrence, a coherent picture of the functional relationship among large and heterogeneous lists of terms were obtained. It affords investigators an extractive interface to complex text data. This paper shows how these documents were mined using text-based WordStat software as well as the potentials, features and options of the program
Inclusion of e-Assist to increase Agile Adoption

Agile methodology promises quality deliverables in frequent intervals. In Agile project development, user stories (requirements) entered in Product backlog is prioritized and according to priority few of them are selected for the current iteration (sprint). These user stories have to be implemented within that sprint. Hence the project team demands experts in the relevant domain for successful completion. Software development organizations have limited number of experts with them and hence the number of projects that follow agile methodology is restricted. This paper first discusses the risk involved if moderately skilled members are chosen for agile software development and then the methods to mitigate the risk so that more number of projects can adopt agile methodology
Mail-Order Bride Industry: The Perpetuation of Transnational Economic Inequalities and Stereotypes

Newspaper and magazine advertisements in the United States1 promise male readers potential brides who are "Gorgeous Pacific Women" and "Pearls of the Orient. "2 The mail-order bride agencies that place these advertisements also offer catalogs filled with pictures of women from Asia, South America, and Eastern Europe, complete with information on each woman's age, weight, height, and interests. ' The advertisements and catalogs are part of an expanding multi-million dollar industry that markets women from developing countries as potential brides to men in Western industrialized nations. The modern mail-order bride industry in some ways mirrors the arranged marriages of the past, where families sent "picture brides" 4 from their homelands to lonely men in foreign countries.
Stability of fractional-order linear time-invariant system with noncommensurate orders

Bounded-input bounded-output stability conditions for fractional-order linear time-invariant (LTI) system with multiple noncommensurate orders have been established in this paper. The orders become noncommensurate orders when they do not have a common divisor. Sufficient and necessary conditions of stability for this kind of fractional-order LTI system with multiple noncommensurate orders. Based on the numerical inverse Laplace transform technique, time-domain responses for a fractional-order system with double noncommensurate orders are presented to illustrate the obtained stability results.
Study of the Further Reduction of Shaft Voltage of Brushless DC Motor With Insulated Rotor Driven by PWM Inverter

The authors previously succeeded in reducing the shaft voltage of a PWM driven motor with a rotor which had an outer core and an inner core (and the shaft), electrically insulated each other by a resin (hereafter, the insulated rotor). This paper proposes a new method for further reduction of the shaft voltage of a motor with an insulated rotor by adding a capacitor between brackets and N line of the dc link of the inverter. A common-mode equivalent circuit of the system with an ungrounded motor is examined, and the effect of further reduction by the new method is verified by calculation of the shaft voltage from the equivalent circuit and measurement of the shaft voltage of the motor.
IUHM: a hypermedia-based model for integrating open services, data and metadata

This paper discusses a new hypermedia-based model known as IUHM (Information Unit Hypermedia Model). IUHM emerged as a result of the development of the OPALES system, a collaborative environment for exploring and indexing video archives in a digital library. A basic design requirement of OPALES is that it must permit and support the integration of new services throughout its life cycle. Thus, IUHM depends heavily upon the notions of extensibility and openness.Support for openness, extensibility and late binding of services is provided in the IUHM model by a single reflexive mechanism. This uniform mechanism is used for describing all relationships between arbitrary system entities, including services, data and metadata. The mechanism in question consists of a generic, computable hypertext structure with typed links, known as the Information Unit (IU), and is the minimal structural scheme to which all encapsulated entities comply.We describe and justify the design of the Information Unit, as well as the semantics of its four link types, namely role, type, owner, relative. We further describe the minimal kernel of the runtime layer responsible for the dynamic behaviour specified by the IUHM compliant hypertext network. We discuss the mechanisms involved in the dynamic binding of services and service composition. We illustrate these notions by real-world examples of the integration of metadata services within the OPALES system.
Involvement of the Reserve Material Poly-β-Hydroxybutyrate in Azospirillum brasilense Stress Endurance and Root Colonization

ABSTRACT When grown under suboptimal conditions, rhizobacteria of the genus Azospirillum produce high levels of poly-β-hydroxybutyrate (PHB). Azospirillum brasilense strain Sp7 and a phbC (PHB synthase) mutant strain in which PHB production is impaired were evaluated for metabolic versatility, for the ability to endure various stress conditions, for survival in soil inoculants, and for the potential to promote plant growth. The carbon source utilization data were similar for the wild-type and mutant strains, but the generation time of the wild-type strain was shorter than that of the mutant strain with all carbon sources tested. The ability of the wild type to endure UV irradiation, heat, osmotic pressure, osmotic shock, and desiccation and to grow in the presence of hydrogen peroxide was greater than that of the mutant strain. The motility and cell aggregation of the mutant strain were greater than the motility and cell aggregation of the wild type. However, the wild type exhibited greater chemotactic responses towards attractants than the mutant strain exhibited. The wild-type strain exhibited better survival than the mutant strain in carrier materials used for soil inoculants, but no difference in the ability to promote plant growth was detected between the strains. In soil, the two strains colonized roots to the same extent. It appears that synthesis and utilization of PHB as a carbon and energy source by A. brasilense under stress conditions favor establishment of this bacterium and its survival in competitive environments. However, in A. brasilense, PHB production does not seem to provide an advantage in root colonization under the conditions tested.
Native Learners' Perceptions of Educational Climate in a Native Employment Preparation Program.

Concerned with the problem of undereducated and unemployed Canadian Native adults, the qualitative study sought to describe the dimensions of educational climate which were influential in providing optimal learning conditions for Native adult learners in a Native Employment Preparation Program. This was a pioneering study which provided rich descriptions about educational climate from the perspectives of Native adult learners. Research questions relating to learner milieu, dimensions of the cultural, social, and instructional environments, and learner outcomes were examined. The cultural environment emerged as the most influential factor contributing to a quality learning environment; the values, cooperation and supportiveness components were found influential in providing effective learning conditions.
Gate-Recessed InAlN/GaN HEMTs on SiC Substrate With Al[subscript 2]O[subscript 3] Passivation

We studied submicrometer (LG = 0.15−0.25 μm) gate-recessed InAlN/AlN/GaN high-electron mobility transistors (HEMTs) on SiC substrates with 25-nm Al2O3 passivation. The combination of a low-damage gate-recess technology and the low sheet resistance of the InAlN/AlN/GaN structure resulted in HEMTs with a maximum dc output current density of IDS,max = 1.5 A/mm and a record peak extrinsic transconductance of gm,ext = 675 mS/mm. The thin Al2O3 passivation improved the sheet resistance and the transconductance of these devices by 15% and 25%, respectively, at the same time that it effectively suppressed current collapse.
Proficient receptive combined address generator archetypal for WiMAX and WiFi deinterleaver precinct

In this paper a combined responsive address generator archetypal for WiMAX and WiFi deinterleaver unit aimed for using in wireless broadband system is being proposed. Deinterleaver is used in conjunction with forward error correction unit for eliminating and correcting different transmission errors which occurs when signals are transmitted from base station to subscriber station. Address generator unit plays a vital role in deciding the overall performance of deinterleaver section. A novel proficient address generator supporting varying modulation schemes such as QPSK, 16-QAM and 64-QAM for both WiMAX and WiFi systems is being proposed in this paper. By combining the address generator unit we can use this design to generate deinterleaver addresses for both WiMAX and WiFi enabled scenarios with ease. The FPGA and 130 nm standard library AS IC results are studied by modelling the design in VHDL.
Conversion technique from neuroendoscopy to microsurgery in ventricular tumors: Technical note

Background: Ventricular tumors represent a major neurosurgical challenge, making endoscopic approach an invaluable tool as it gained importance due to technological advances. Nevertheless, the method is not exempt of risk and limitations, sometimes requiring an open surgery. Thus, initial measurements must be adopted in order to simplify an eventual need for conversion to open craniotomy. Methods: Here, we describe a series of 6 patients with ventricular tumors approached by neuroendoscopy where the conversion to microsurgery turned out to be necessary. Patients’ average age was 59.5 years (39–75 years). Average tumoral size was 17.8 mm (15–21 mm). There were 2 cases of lateral ventricle subependymoma and 4 cases of third ventricle colloid cysts. A standard surgical incision was performed in the coronal direction, allowing lateral expansion to 10 cm. Moreover, the endoscopic burr hole was enlarged to a 5 cm craniotomy. A small enlargement of the endoscopic cortical access was performed to gain a transcortical microsurgical corridor to the ventricular cavity. The need for conversion arose due to high consistency of the tumor (3 cases), technical problems (2 cases), and cortical collapse (1 case). Results: There was one case of cerebrospinal fluid fistula and infection and one case of transitory memory disturbance. In both the cases, we obtained a complete functional recovery. Clinical and radiological follow-up showed total tumor removal with no recurrences. Conclusions: The technique herein described was easy to perform, promptly bypassed the endoscopic limitations, and gathered excellent surgical results. The possibility of adapting the method to other tumor locations may be considered.
Towards Highly Automated Driving: Intermediate report on the HAVEit-Joint System

This overview article describes the goals, concepts and very preliminary results of the subproject Joint System within the EU-project HAVEit. The goal of HAVEit is to develop and investigate vehicle automation beyond ADAS systems, especially highly automated driving, where the automation is doing a high percentage of the driving, while the driver is still meaningfully involved in the driving task. In HAVEit, an overarching architecture and several prototypes will be built up over time by manufacturers and suppliers. As a trail blazer, a Joint System prototype is under development by an interdisciplinary team of several European research institutes in order to investigate and demonstrate the basic principles of highly automated driving, which will then be gradually applied to vehicles closer to serial production. Starting with sensor data fusion, the Co-System part of the Joint Systems plans manoeuvres and trajectories, which are then used to control active interfaces and, taking into account the results of an online driver assessment, joined with the actions of the driver. While many aspects of this research undertaking are still under investigation, the concept, a first prototype and first results from a simulator evaluation will be sketched.
The Prevalence and Risk Factors for Depression Symptoms in a Rural Chinese Sample Population

Background It is essential to understand how we can prevent and treat the epidemic of depression. Several studies have reported the prevalence of depressive symptoms in the urban population in China, but there is a lack of information regarding the prevalence of depression in rural populations. Objective To understand the prevalence of depression in a rural Chinese population and to analyze the risk factors for depression. Methods This study used a cross-sectional approach. A total of 11,473 subjects were surveyed and completed the Patient Health Questionnaire-9 (PHQ-9) and the World Health Organization Quality of Life Brief scales. Living conditions, per capita income, marital status, and information about dietary health and chronic disease status were assessed. Results The prevalence of depressive symptoms in the population was 5.9%. The prevalence in women (8.1%) was higher compared with men (3.5%) and also increased with age. The per capita income level, amount of sleep obtained per day, education level, weekly consumption of meat and beans or bean products, salt intake, and chronic disease status were associated with depressive symptoms. The quality of life of individuals with a score less than 10 points on the PHQ-9 was significantly better compared with individuals with a score greater than 10. Conclusion The prevalence of depressive symptoms among rural population is higher than some southern cities in China. Dietary patterns may be an important risk factor linked to this disorder in the Chinese rural population.
Essay Assessment 1 Running Head: Essay Assessment Essay Assessment with Latent Semantic Analysis Essay Assessment with Latent Semantic Analysis Essay Assessment with Latent Semantic Analysis

Latent semantic analysis (LSA) is an automated, statistical technique for comparing the semantic similarity of words or documents. In this paper, I examine the application of LSA to automated essay scoring. I compare LSA methods to earlier statistical methods for assessing essay quality, and critically review contemporary essay-scoring systems built on LSA, including the Intelligent Essay Finally, I discuss current avenues of research, including LSA's application to computer-measured readability assessment and to automatic summarization of student essays. Few would deny the importance of practice in the development of good writing skills. Like playing a musical instrument, writing is something that cannot be taught by directions or example alone. Practicing writing, and receiving constructive criticism on these attempts, is an integral part of the learning process. Furthermore, the quality of an essay is regarded as one of the best measures of the author's knowledge of the topic. Writing essays requires more thought than many other forms of testing, such as multiple-choice exams, since the students must construct their own coherent answers and justifications therefor. Well-developed and appropriately scored writing assessments can test not only students' prowess with language, but also their ability to synthesize and analyze information; to find new connections between ideas and to explain their significance. (Bereiter & Scardamalia, 1987) Unfortunately, assessing student writing and providing thoughtful feedback is extremely labour-intensive and time-consuming. Instructors are often faced with the difficult decision of assigning fewer writing assignments or marking them less thoroughly. Until recently, little thought was given to the idea of automating the essay-scoring process. Early computerized writing assessors focused on mechanical properties—grammar, spelling, punctuation—and on simple stylistic features, such as wordiness and overuse of the passive voice. However, syntax and style alone are not sufficient to judge the merits of an essay. Enter latent semantic analysis (LSA), a relatively new statistically based ESSAY ASSESSMENT 4 technique for comparing the semantic similarity of texts. In this report, I survey the use of LSA as a tool for measuring the comprehensibility, coherence, and comprehensiveness of student essays. The next section examines the feasibility of previous computer-based techniques for scoring essays. Following this is a description of how LSA is used to assess essays, and a discussion of some current LSA-based systems. In the final section, I discuss how LSA-based essay scoring is being used in related applications such as readability assessment. I also touch on some future areas of research …
Spectral Methods Cluster Words of the Same Class in a Syntactic Dependency Network

We analyze here a particular kind of linguistic network where vertices represent words and edges stand for syntactic relationships between words. The statistical properties of these networks have been recently studied and various features such as the small-world phenomenon and a scale-free distribution of degrees have been found. Our work focuses on four classes of words: verbs, nouns, adverbs and adjectives. Here, we use spectral methods sorting vertices. We show that the ordering clusters words of the same class. For nouns and verbs, the cluster size distribution clearly follows a power-law distribution that cannot be explained by a null hypothesis. Long-range correlations are found between vertices in the ordering provided by the spectral method. The findings support the use of spectral methods for detecting community structure.
Examining Novice Teacher Development through the Clinical Supervision Process: A Participatory Action Research

The first clinical supervision experience can significantly impact a novice teacher‟s overall success during the early years of their teaching career (Robinson, 1998). It is a very stressful, challenging time, and for many, it is the first time he/she is asked to take on multiple roles aside from direct instruction and professional responsibilities (Sykes, 1996). As districts work to better align policies and induction programs with the changing needs of novice teachers, they must face the fact that they serve powerful roles as teacher educators, mentors, and retainers. It is important for administrators to self-assess how districts are meeting or failing to meet these needs (Grossman & Thompson, 2004). Prescriptive mentoring programs cited by Smith & Ingersoll (2004) have failed to meet the mark. This study will attempt to provide thick description of the clinical supervision process through the lens of novice teachers. 1. Statement of the research question(s)
Exploring term temporality for pseudo-relevance feedback

As digital collections expand, the importance of the temporal aspect of information has become increasingly apparent. The aim of this paper is to investigate the effect of using long-term temporal profiles of terms in information retrieval by enhancing the term selection process of pseudo-relevance feedback (PRF). For this purpose, two temporal PRF approaches were introduced considering only temporal aspect and temporal along with textual aspect. Experiments used the AP88-89 and WSJ87-92 test collections with TREC Ad-Hoc Topics 51-100. Term temporal profiles are extracted from the Google Books n-grams dataset. The results show that the long-term temporal aspects of terms are capable of enhancing retrieval effectiveness.
Dissociated Neurons and Glial Cells Derived from Rat Inferior Colliculi after Digestion with Papain

The formation of gliosis around implant electrodes for deep brain stimulation impairs electrode–tissue interaction. Unspecific growth of glial tissue around the electrodes can be hindered by altering physicochemical material properties. However, in vitro screening of neural tissue–material interaction requires an adequate cell culture system. No adequate model for cells dissociated from the inferior colliculus (IC) has been described and was thus the aim of this study. Therefore, IC were isolated from neonatal rats (P3_5) and a dissociated cell culture was established. In screening experiments using four dissociation methods (Neural Tissue Dissociation Kit [NTDK] T, NTDK P; NTDK PN, and a validated protocol for the dissociation of spiral ganglion neurons [SGN]), the optimal media, and seeding densities were identified. Thereafter, a dissociation protocol containing only the proteolytic enzymes of interest (trypsin or papain) was tested. For analysis, cells were fixed and immunolabeled using glial- and neuron-specific antibodies. Adhesion and survival of dissociated neurons and glial cells isolated from the IC were demonstrated in all experimental settings. Hence, preservation of type-specific cytoarchitecture with sufficient neuronal networks only occurred in cultures dissociated with NTDK P, NTDK PN, and fresh prepared papain solution. However, cultures obtained after dissociation with papain, seeded at a density of 2×104 cells/well and cultivated with Neuro Medium for 6 days reliably revealed the highest neuronal yield with excellent cytoarchitecture of neurons and glial cells. The herein described dissociated culture can be utilized as in vitro model to screen interactions between cells of the IC and surface modifications of the electrode.