Miracle-dz/UniFAR-FTUs huggingface dataset:
Low transmission loss, simple, and broadband waveguide-to-microstrip line transducer in V-, E- and W-band

A low transmission loss, simple mechanical structure, and broadband waveguide-to-microstrip line transducer has been developed with a polytetrafluoroethylene printed circuit board. This can fully cover the V-band, E-band, and W-band, and the transmission losses are typically 0.68 dB, 0.86 dB, and 0.78 dB, respectively, at the center frequency of each band. The transducer in the W-band was already implemented in a W-band 2nd-order harmonic mixer. In this letter, we report the development of the millimeter-wave waveguide-to-microstrip line transducer.
Spatial Clustering Algorithm Based on Optimized-Division

Traditional grid-density based spatial clustering algorithms divide input data space into partitions with same width and neglect the natural distributing character of initial data space. A new robust spatial clustering algorithm based on optimized-division (OpD-Clus) is proposed in this paper. Spatial data space is divided by hyper-planes which are encertained with axis-paralleled histogram in OpD-Clus algorithm. Division of data space relies on natural distributing character of input data space to improve the accuracy and efficiency of spatial clustering. Simultaneously, the outstanding difference between density-region and spare-region makes setting of density threshold parameter easily and reduces the parameter dependence of spatial clustering algorithm. The validity, efficiency and un-sensitivity of parameters of OpD-Clus algorithm is demonstrated by experiment results.
Analysis and compensation for the joint effects of HPA nonlinearity, I/Q imbalance and crosstalk in MIMO beamforming systems

In this paper, we investigate the joint effects of high-power amplifier (HPA) nonlinearity, in-phase/quadrature-phase (I/Q) imbalance and crosstalk, on the performance of multiple-input multiple-output (MIMO) transmit beamforming (TB) systems, and propose a compensation method for the three impairments together. The performance of the MIMO TB system equipped with the proposed compensation scheme is evaluated in terms of average symbol error probability and capacity when transmissions are performed over uncorrelated Rayleigh fading channels. Numerical results are provided and show the effects on performance of several system parameters, namely, the HPA parameters, image-leakage ratio, crosstalk, numbers of antennas, length of pilot symbols and phase-shift keying modulation order.
Inflammatory macrophages in pancreatic acinar cell metaplasia and initiation of pancreatic cancer

The roles of inflammatory macrophages in pancreatic tissue and the development of pancreatic cancer have not been well characterized. Recently it was shown that inflammatory macrophages, besides their function in clearing dead cells, also initiate pancreatic acinar cell metaplasia to duct-like progenitor cells. While in pancreatitis this is a reversible process, in context of an oncogenic stimulus this process is irreversible and can lead to the formation of precancerous lesions. Recent work now indicates that acquisition of an activating Kras mutation in acinar cells initiates signaling that leads to chemoattraction of M1-poliarized macrophages. This oncogene-caused chronic microinflammation can accelerate the pathogenesis of pancreatic cancers.
A New Web Search Result Clustering based on True Common Phrase Label Discovery

Web search results clustering are navigator for users to search results. Therefore the correct cluster label is important which has been index the set of web document. Suffix tree clustering (STC) is fast automatically clustering and labeling. However, STC is inadequate since they generate interrupted cluster label due to using n-gram technique. In this paper, we propose an approach for web search results clustering and labeling based on a new suffix tree data structure, a new base cluster combining algorithm with a new partial phase join operation. The algorithm for constructing the data structure is an incremental and a linear time algorithm. Thus, the proposed approach is suitable for on-the-fly the web search results clustering and labeling cluster. The proposed approach provides more readable and true common phrase of web document cluster than conventional web search result clustering. Experimental results also show that the proposed approach has better performance than that of conventional web search result clustering.
Carbon-Nitrogen-Oxygen Line Radiation and the X-Ray Bowen Fluorescence Mechanism in Optically Thick, Highly Ionized Media

Radiative transfer effects due to overlapping X-ray lines in a high-temperature, optically thick, highly ionized medium are investigated. One particular example, in which the O VIII Lyα doublet (2 2P1/2,3/2-1 2S1/2) coincides in frequency with the N VII Lyζ lines (7 2P1/2,3/2-1 2S1/2), is studied in detail to illustrate the effects on the properties of the emergent line spectrum. We solve the radiative transfer equation to study the energy transport of resonance-line radiation in a static, infinite, plane-parallel geometry, which is used to compute the destruction/escape probabilities for each of the lines for various total optical thicknesses of the medium, as well as destruction probabilities by sources of underlying photoelectric opacity. It is found that a large fraction of the O VIII Lyα line radiation can be destroyed by N VII, which can result in a reversal of the O VIII Lyα/N VII Lyα line intensity ratio similar to what may be seen under nonsolar abundances. Photoelectric absorption by ionized carbon and nitrogen can also subsequently increase the emission-line intensities of these ions. We show that line ratios, which are directly proportional to the abundance ratios in optically thin plasmas, are not good indicators of the true CNO abundances. Conversely, global spectral modeling that assumes optically thin conditions may yield incorrect abundance estimates when compared with observations, especially if the optical depth is large. Other potentially important overlapping lines and continua in the X-ray band are also identified, and their possible relevance to recent high-resolution spectroscopic observations with Chandra and XMM-Newton are briefly discussed.
New Distance Measure for Microarray Gene Expressions Using Linear Dynamic Range of Photo Multiplier Tube

This paper deals with a new distance measure for genes using their microarray expressions. The distance measure is called, "maxrange distance ", where an experiment specific normalization factor is incorporated in the computation of the distance. The normalization factor is dependent on the linear dynamic range of the photo multiplier tube (PMT) for scanning fluorescence intensities of the gene expression values. Superiority of this distance measure in the microarray gene ordering problem has been extensively established on widely studied microarray data sets by performing statistical tests
Non-volatile FPGAs based on spintronic devices

This paper presents an innovative architecture for radiation-hardened FPGA (Field Programmable Gate Array). This architecture is based on the use of MTJs (Magnetic Tunnel Junctions), magnetic nanostructures used as basic elements of MRAM (Magnetic Random Access Memory). These devices are totally immune to radiations and can be used as a reference memory to perform “scrubbing” techniques, which consist in regularly reloading the configuration of the FPGA to fix the radiation induced errors that may have occured. This approach allows hardening the circuits at low cost in terms of area, while reducing the standby power consumption and offering new functionalities, like dynamic reconfiguration. A silicon demonstrator was implemented, including a 2-inputs LUT (Look Up Table) and tested using a digital tester, giving encouraging results.
Amygdala Functional Connectivity Predicts Pharmacotherapy Outcome in Pediatric Bipolar Disorder

The aim of this study was to determine functional connectivity among patients with pediatric bipolar disorder (PBD) who are responders to pharmacotherapy and those who are nonresponders, and learn how they differ from healthy controls (HC) while performing a task that engages affective and cognitive neural systems. PBD participants (n = 34; 13.4 ± 2.3 years) were defined as responders if there was ≥ 50% improvement in Young Mania Rating Scale (YMRS) scores (n = 22) versus nonresponders with < 50% improvement (n = 12) with one of three mood stabilizing medications (divalproex, risperidone, or lamotrigine). HC (n = 14; 14.2 ± 3.1 years) participants also were scanned at baseline and follow-up. During functional magnetic resonance imaging, participants performed a color-matching task in which they had to match the color of positive, negative, or neutral words with colored dots. Independent component analysis was used to identify functionally connected networks across the whole brain, which were subsequently interrogated using region-of-interest analyses to test for group differences. A frontolimbic network was identified that showed impaired functional integration in PBD relative to HC when participants viewed negatively valenced words. PBD medication responders showed greater connectivity of the amygdala into the network before and after treatment compared with nonresponders, with responders showing a pattern more similar to HC than to nonresponders. Regardless of medication type, the degree of amygdala functional connectivity predicted medication response as well as the improvement in YMRS scores across responders and nonresponders. These findings suggest that increased functional integration of the amygdala within the frontolimbic network might be a biomarker of general mood stabilizer medication responsivity in bipolar disorder.
Brillouin and raman scattering in silicon and silicon nitride photonic integrated circuits (invited paper)

Silicon photonics has gained considerable momentum as a platform for the on-chip integration of advanced photonic functions on the basis of CMOS-technology, especially in the fields of telecom and datacom. Here we report on the use of this platform for photon-phonon interaction in nanophotonic silicon or silicon nitride waveguides. We discuss the first demonstration of Brillouin gain in silicon waveguides as well as Raman spectroscopy taking advantage of silicon nitride photonic circuits.
Multicast for small conferences

This paper describes a concept to support scalable multicast communications for small audio/video conferencing groups on the Internet. The solution presented in this paper is based on extensions of IPv6 and the session description protocol (SDP). A goal of the concept called multicast for small conferences (MSC) is the smooth deployment in the Internet.
Partial Replication of Metadata to Achieve High Metadata Availability in Parallel File Systems

This paper presents PARTE, a prototype parallel file system with active/standby configured metadata servers (MDSs). PARTE replicates and distributes a part of files' metadata to the corresponding metadata stripes on the storage servers (OSTs) with a per-file granularity, meanwhile the client file system (client) keeps certain sent metadata requests. If the active MDS has crashed for some reason, these client backup requests will be replayed by the standby MDS to restore the lost metadata. In case one or more backup requests are lost due to network problems or dead clients, the latest metadata saved in the associated metadata stripes will be used to construct consistent and up-to-date metadata on the standby MDS. Moreover, the clients and OSTs can work in both normal mode and recovery mode in the PARTE file system. This differs from conventional active/standby configured MDSs parallel file systems, which hang all I/O requests and metadata requests during restoration of the lost metadata. In the PARTE file system, previously connected clients can continue to perform I/O operations and relevant metadata operations, because OSTs work as temporary MDSs during that period by using the replicated metadata in the relevant metadata stripes. Through examination of experimental results, we show the feasibility of the main ideas presented in this paper for providing high availability metadata service with only a slight overhead effect on I/O performance. Furthermore, since previously connected clients are never hanged during metadata recovery, in contrast to conventional systems, a better overall I/O data throughput can be achieved with PARTE.
Real-world application of new sensor technologies for air quality monitoring

The European Topic Centre on Air Pollution and Climate Change Mitigation (ETC/ACM) is a consortium of European institutes under contract of the European Environment Agency RIVM UBA-V ÖKO AEAT EMISIA CHMI NILU VITO INERIS 4Sfera PBL CSIC 2 Front page picture: Picture recreating citizens' participation in air quality monitoring by using low-cost sensors during their daily life, such as when commuting by bike. The picture was created by ESN for the EU FP7 project CITI-SENSE. This ETC/ACM Technical Paper has not been subjected to European Environment Agency (EEA) member country review. It does not represent the formal views of the EEA.
Towards a Top-K SPARQL Query Benchmark

The research on optimization of top-k SPARQL query would largely benefit from the establishment of a benchmark that allows comparing different approaches. For such a benchmark to be meaningful, at least two requirements should hold: 1) the benchmark should resemble reality as much as possible, and 2) it should stress the features of the top-k SPARQL queries both from a syntactic and performance perspective. In this paper we propose Top-k DBPSB: an extension of the DBpedia SPARQL benchmark (DBPSB), a benchmark known to resemble reality, with the capabilities required to compare SPARQL engines on top-k queries.
Prospective study on long-term dietary patterns and incident depression in middle-aged and older women.

BACKGROUND Although individual nutrients have been investigated in relation to depression risk, little is known about the overall role of diet in depression. OBJECTIVE We examined whether long-term dietary patterns derived from a food-frequency questionnaire (FFQ) predict the development of depression in middle-aged and older women. DESIGN We conducted a prospective study in 50,605 participants (age range: 50-77 y) without depression in the Nurses' Health Study at baseline (1996) who were followed until 2008. Long-term diet was assessed by using FFQs every 4 y since 1986. Prudent (high in vegetables) and Western (high in meats) patterns were identified by using a principal component analysis. We used 2 definitions for clinical depression as follows: a strict definition that required both a reported clinical diagnosis and use of antidepressants (3002 incident cases) and a broad definition that further included women who reported either a clinical diagnosis or antidepressant use (7413 incident cases). RESULTS After adjustment for age, body mass index, and other potential confounders, no significant association was shown between the diet patterns and depression risk under the strict definition. Under the broad definition, women with the highest scores for the Western pattern had 15% higher risk of depression (95% CI: 1.04, 1.27; P-trend = 0.01) than did women with the lowest scores, but after additional adjustment for psychological scores at baseline, results were no longer significant (RR: 1.09; 95% CI: 0.99, 1.21; P-trend = 0.08). CONCLUSION Overall, results of this large prospective study do not support a clear association between dietary patterns from factor analysis and depression risk.
Second-tier cache management using write hints

Storage servers, as well as storage clients, typically have large memories in which they cache data blocks. This creates a two-tier cache hierarchy in which the presence of a first-tier cache (at the storage client) makes it more difficult to manage the second-tier cache (at the storage server). Many techniques have been proposed for improving the management of second-tier caches, but none of these techniques use the information that is provided by writes of data blocks from the first tier to help manage the second-tier cache. In this paper, we illustrate how the information contained in writes from the first tier can be used to improve the performance of the second-tier cache. In particular, we argue that there are very different reasons why storage clients write data blocks to storage servers (e.g., cleaning dirty blocks vs. limiting the time to recover from failure). These different types of writes can provide strong indications about the current state and future access patterns of a first-tier cache, which can help in managing the second-tier cache. We propose that storage clients inform the storage servers about the types of writes that they perform by passing write hints. These write hints can then be used by the server to manage the second-tier cache. We focus on the common and important case in which the storage client is a database system running a transactional (OLTP) workload. We describe, for this case, the different types of write hints that can be passed to the storage server, and we present several cache management policies that rely on these write hints. We demonstrate using trace driven simulations that these simple and inexpensive write hints can significantly improve the performance of the second-tier cache.
Perceptual Biases in Font Size as a Data Encoding

Many visualizations, including word clouds, cartographic labels, and word trees, encode data within the sizes of fonts. While font size can be an intuitive dimension for the viewer, using it as an encoding can introduce factors that may bias the perception of the underlying values. Viewers might conflate the size of a word's font with a word's length, the number of letters it contains, or with the larger or smaller heights of particular characters (‘o’ versus ‘p’ versus ‘b’). We present a collection of empirical studies showing that such factors—which are irrelevant to the encoded values—can indeed influence comparative judgements of font size, though less than conventional wisdom might suggest. We highlight the largest potential biases, and describe a strategy to mitigate them.
Dynamics of the Cytotoxic T Cell Response to a Model of Acute Viral Infection

ABSTRACT A detailed characterization of the dynamics and breadth of the immune response to an acute viral infection, as well as the determinants of recruitment to immunological memory, can greatly contribute to our basic understanding of the mechanics of the human immune system and can ultimately guide the design of effective vaccines. In addition to neutralizing antibodies, T cells have been shown to be critical for the effective resolution of acute viral infections. We report the first in-depth analysis of the dynamics of the CD8+ T cell repertoire at the level of individual T cell clonal lineages upon vaccination of human volunteers with a single dose of YF-17D. This live attenuated yellow fever virus vaccine yields sterile, long-term immunity and has been previously used as a model to understand the immune response to a controlled acute viral infection. We identified and enumerated unique CD8+ T cell clones specifically induced by this vaccine through a combined experimental and statistical approach that included high-throughput sequencing of the CDR3 variable region of the T cell receptor β-chain and an algorithm that detected significantly expanded T cell clones. This allowed us to establish that (i) on average, ∼2,000 CD8+ T cell clones were induced by YF-17D, (ii) 5 to 6% of the responding clones were recruited to long-term memory 3 months postvaccination, (iii) the most highly expanded effector clones were preferentially recruited to the memory compartment, and (iv) a fraction of the YF-17D-induced clones could be identified from peripheral blood lymphocytes solely by measuring clonal expansion. IMPORTANCE The exhaustive investigation of pathogen-induced effector T cells is essential to accurately quantify the dynamics of the human immune response. The yellow fever vaccine (YFV) has been broadly used as a model to understand how a controlled, self-resolving acute viral infection induces an effective and long-term protective immune response. Here, we extend this previous work by reporting the identity of activated effector T cell clones that expand in response to the YFV 2 weeks postvaccination (as defined by their unique T cell receptor gene sequence) and by tracking clones that enter the memory compartment 3 months postvaccination. This is the first study to use high-throughput sequencing of immune cells to characterize the breadth of the antiviral effector cell response and to determine the contribution of unique virus-induced clones to the long-lived memory T cell repertoire. Thus, this study establishes a benchmark against which future vaccines can be compared to predict their efficacy.
Identification of Cdc37 as a Novel Regulator of the Stress-Responsive Mitogen-Activated Protein Kinase

ABSTRACT Eukaryotic cells utilize multiple mitogen-activated protein kinases (MAPKs) to transmit various extracellular stimuli to the nucleus. A subfamily of MAPKs that mediates environmental stress stimuli is also called stress-activated protein kinase (SAPK), which has crucial roles in cellular survival under stress conditions as well as inflammatory responses. Here we report that Cdc37, an evolutionarily conserved kinase-specific chaperone, is a positive regulator of Spc1 SAPK in the fission yeast Schizosaccharomyces pombe. Through a genetic screen, we have identified cdc37 as a mutation that compromises signaling through Spc1 SAPK. The Cdc37 protein physically interacts with Spc1, and the cdc37 mutation affects both the cellular level of the Spc1 protein and stress-induced Spc1 phosphorylation by Wis1 MAPK kinase (MAPKK). Consistently, expression of the stress response genes regulated by the Spc1 pathway is compromised in cdc37 mutant cells. On the other hand, a mutation in Hsp90, which often cooperates with Cdc37 in chaperoning protein kinases, does not affect Spc1 SAPK. These results suggest that Spc1 SAPK is a novel client protein for the Cdc37 chaperone, and the Cdc37 function is important to maintain the stability of the Spc1 protein and to facilitate stress signaling from Wis1 MAPKK to Spc1 SAPK.
RF-MEMS switched varactors for medium power applications

In RF (radio frequency) domain, one of the limitations of using MEMS (micro electromechanical systems) switching devices for medium power applications is RF power. Failure phenomena appear even for 500 mW. A design of MEMS switched capacitors with an enhanced topology is presented in this paper to prevent it. This kind of device and its promising performances will serve to fabricate a MEMS based phase shifter able to work under several watts.
Neutron Diffraction Study of Elastoplastic Behaviour of Al/SiCp Metal Matrix Composite

The TOF neutron diffraction measurements were done for Al/SiCp metal–matrix composite (17% of SiC) subjected to T6 thermal treatment. Using three separated diffraction peaks of SiC phase and four peaks of Al phase, the lattice strains were measured for both phases independently during in situ tensile test. The experimental results were presented in comparison with elastoplastic model, which allows to find the values of parameters determining plastic deformation of Al matrix (critical resolved shear stress and hardening parameter). Additionally, the results of TOF method were compared with those which were obtained with monochromatic neutron radiation (LLB, Saclay). In the latter experiment Al/SiCp composite containing 25% of SiC was measured. It was shown that after elastoplastic deformation the mismatch stresses determined for both phases relax during tensile deformation.