Miracle-dz/UniFAR-FTUs huggingface dataset:
Cochlear implant-mediated perception of music

Purpose of reviewThis paper examines and consolidates recent advances in cochlear implant sound processing from the perspective of music perception, which is increasingly viewed as one of the most difficult of all listening conditions. Recent findingsMusic is an essentially abstract, complex form of sound composed of multiple layers of sounds that vary in temporal presentation, frequency distribution, and harmonic content. As a result, music perception is perhaps the most challenging aspect of implant-mediated listening. Thus far, implant performance has shown poor performance overall during perception of musical pitches, melodies, and timbre while perception of rhythm is relatively good. Recent advances in implant sound processing strategies, particularly the use of current distribution along adjacent electrodes, have promising early results in terms of improving the number of pitch percepts available to cochlear implant listeners. SummaryMusic perception poses auditory challenges that can exceed those of language perception during cochlear implant-mediated listening. These challenges should be emphasized to patients prior to implantation. Although rhythm perception via cochlear implants is reasonably good using simple test paradigms, significant work remains to improve critically important aspects of music perception, including melody and timbre. New implant processing strategies are encouraging and should lead to improved music perception in the near future.
The Evocative Object - Introspection and Emotional Reflection Through Computer Use

Mobilizing the modernist ethos of ‘analyze and you shall know’, this article critically reconsiders the nexus of emotion, interaction and design in human–computer interaction. In particular, this article examines interactional affective computing, and it elaborates upon its underlying notion of emotion, making a case for the role of introspective reflection for emotional experience and expression. Moreover, the article offers a critical reading of two interactional affective design prototypes. On this basis, the article formulates three pairs of design concepts, all of which address the question how emotional reflection can be curated.
Particle uptake efficiency is significantly affected by type of capping agent and cell line

Surface‐functionalized silver nanoparticles (AgNPs) are the most deployed engineered nanomaterials in consumer products because of their optical, antibacterial and electrical properties. Almost all engineered nanoparticles are coated with application‐specific capping agents (i.e. organic/inorganic ligands on particle surface) to enhance their stability in suspension or increase their biocompatibility for biomedicine. The aim of this study was to investigate the contribution of the selected capping agents to their observed health impacts using realistic dose ranges. AgNPs capped with citrate, polyvinylpyrrolidone (PVP) and tannic acid were studied with human bronchoalveolar carcinoma (A549) and human colon adenocarcinoma (Caco‐2) cell lines and compared against exposures to Ag ions. Cellular uptake and cytotoxicity were evaluated up to 24 h. Tannic acid capped AgNPs induced higher cellular uptake and rate in both cell lines. Citrate‐capped and PVP‐capped AgNPs behaved similarly over 24 h. All three of the capped AgNPs penetrated more into the A549 cells than Caco‐2 cells. In contrast, the uptake rate of Ag ions in Caco‐2 cells (0.11 ± 0.0001 µg h–1) was higher than A549 cells (0.025 ± 0.00004 µg h–1). The exposure concentration of 3 mg l–1 is below the EC50 value for all of the AgNPs; therefore, little cytotoxicity was observed in any experiment conducted herein. Exposure of Ag ions, however, interrupted cell membrane integrity and cell proliferation (up to 70% lysed after 24 h). These findings indicate cellular uptake is dependent on capping agent, and when controlled to realistic exposure concentrations, cellular function is not significantly affected by AgNP exposure. Copyright © 2015 John Wiley & Sons, Ltd.
ADVANCES IN THE ASSESSMENT AND TREATMENT OF JUVENILE OFFENDERS

This paper provides an introduction to best practices in the assessment and treatment of juvenile offenders. Many of the guidelines presented in the paper derive from recent theory and research in criminology and psychology. Much of that research has been conducted in western societies, and it remains to be seen to what extent conclusions from that research can generalize beyond those settings. However, clinical experience suggests that many of the principles of best practice do have application across a broad range of cultures. This paper reflects a child welfare/rehabilitation orientation toward the treatment of the juvenile offender. As explained below, current theory and research from psychology and criminology support the position that juvenile justice systems focusing on the identification and amelioration of criminogenic deficits in the youth and their circumstances produce more positive outcomes than other approaches, including those focusing on punitive sanctions. As well, the implications of the child welfare/rehabilitation model for the treatment of the youth are fully consistent with the UNICEF Guiding Principles for Organizations and Individuals Dealing with Child Welfare and the United Nations Convention on the Right of the Child. The paper begins with a discussion of alternative approaches to the treatment of offenders within juvenile justice systems. This is followed by a brief introduction to contemporary theory and research on the causes and correlates of youth crime and the most efficacious approaches for addressing this serious problem. A discussion of best practices in the assessment of juvenile offenders is then presented. This includes an identification of some useful assessment instruments and procedures as well as practical guidelines in the conduct of assessments. The following section presents a discussion of effective strategies for case planning and management, including the identification of evidence-based treatments.
CCR5 Mutations Distinguish N-Terminal Modifications of RANTES (CCL5) with Agonist versus Antagonist Activity

ABSTRACT CCR5 is the major HIV-1 entry coreceptor. RANTES/CCL5 analogs are more potent inhibitors of infection than native chemokines; one class activates and internalizes CCR5, one neither activates nor internalizes, and a third partially internalizes without activation. Here we show that mutations in CCR5 transmembrane domains differentially impact the activity of these three inhibitor classes, suggesting that the transmembrane region of CCR5, a key interaction site for inhibitors, is a sensitive molecular switch, modulating receptor activity.
Genome Sequence of Lactobacillus cypricasei KCTC 13900

ABSTRACT Lactobacillus cypricasei KCTC 13900 is important in the generation of particular flavors and in other ripening processes associated with specific cheeses. Here, we announce the draft genome sequence of Lactobacillus cypricasei KCTC 13900, isolated from cheeses, and describe major findings from its annotation.
Routing and wavelength assignment for advance reservation in wavelength-routed WDM optical networks

Advance reservation is a useful network service that can not only provide guaranteed services for real-time applications but also allow networks to better plan their resource allocations. In this paper, we explore advance reservation in optical networks and focus on the design of effective routing and wavelength assignment (RWA) algorithms to support advance reservation service in wavelength-routed WDM networks. We first introduce the advance reservation concept and present an advance reservation model. Based on this reservation model, we study the design of effective RWA algorithms for different types of advance reservation and give some example algorithms. We also discuss related issues involved in supporting the coexistence of advance and immediate reservations. In addition, we briefly review some related work on advance reservation and the underlying RWA problem in wavelength-routed WDM networks.
JJP Valeton jr as godsdienshistorikus

JJP Valeton Jnr was one of the main founders of the theological current in nineteenth century Holland called 'the ethical theology'. Some of the most prominent members of this current were, like Valeton, Old Testament specialists. One of the main characteristics of the ethicals was their distinction between scientific knowledge and the knowledge of faith. This enabled them to adopt a critical approach to the Bible while at the same time remaining active in the service of the church. In this article it is shown how Valeton applied this principle in his work on the history of Israelite religion. An attempt is made to demonstrate how his insight was more penetrating than that of even the great Abraham Kuenen.
Utility of the SEER-Medicare Data to Identify Chemotherapy Use

Background. Medicare claims include codes for chemotherapy administration and specific drugs given, and researchers are increasingly using these data to measure the use of chemotherapy. However, the validity and completeness of these data as a source of information has not been established. Objectives. This analysis is intended to assess the utility of the Medicare claims to capture chemotherapy use. Methods. Persons with breast, colorectal, and ovarian cancer were identified from the linked SEER-Medicare data. Their Medicare claims were reviewed to determine if there were any bills for chemotherapy, and if so, if there were claims for specific agents. This information was compared with data on the first course of treatment obtained from hospitals and treating physicians by the SEER registries through an NCI-supported Patterns of Care Studies (POC). Agreement was measured using &kgr; statistics. The sensitivity of the Medicare claims to capture chemotherapy, as reported from the POC data, was also measured. An additional comparison assessed the agreement between the two data sources concerning which specific drugs had been given. Results. For all of the cancers, there was a high level of agreement between the Medicare claims and the POC data regarding whether or not the patient had received chemotherapy (&kgr; ≥0.73). The sensitivity of the Medicare data to determine if a person had received chemotherapy was high (≥88%). In cases where the Medicare claim included a code for a specific drug, there high agreement between Medicare and POC about the specific drug given in breast and colorectal cancers, although the agreement was lower for ovarian cancers. The sensitivity of the Medicare claims to identify specific agents varies by cancer type. Conclusions. The Medicare claims can be used to identify which persons are receiving chemotherapy. The utility of Medicare data to measure treatment with specific agents varies by cancer type and specific agent. For some cancers, it is possible to use these claims to assess use of specific drugs, while for other drugs the data are limited.
Characterization and formulation into solid dosage forms of a novel bacteriophage lytic against Klebsiella oxytoca

Aim To isolate and characterize bacteriophage lytic for the opportunistic pathogen Klebsiella oxytoca and their formulation into a range of solid dosage forms for in-vitro testing. Methods and results We report the isolation, genomic and functional characterization of a novel bacteriophage lytic for Klebsiella oxytoca, which does not infect the closely related Klebsiella pneumoniae. This bacteriophage was formulated into suppositories and troches and shown to be released and lyse underlying Klebsiella oxytoca bacteria in an in-vitro model. These bacteriophage formulations were stable for at least 49 days at 4°C. Conclusions The successful in-vitro assay of these formulations here suggests that they could potentially be tested in-vivo to determine whether such a therapeutic approach could modulate the gut microbiome, and control Klebsiella oxytoca overgrowth, during antibiotic therapy regimes. Significance and impact of the study This study reports a novel bacteriophage specific for Klebsiella oxytoca which can be formulated into solid dosage forms appropriate for potential delivery in testing as a therapy to modulate gut microbiome during antibiotic therapies.
Whistleblowers , Amnesty , and Managerial Fraud : An Experimental Investigation * January , 2016

We examine the effects of increasing transparency and accountability within managerial teams, as well as granting amnesty to whistleblowers, on the incentive to commit fraud. We develop a theoretical model to investigate these issues and then use it as the foundation for a controlled laboratory experiment. Theory predicts that, although whistleblowing should not occur in equilibrium, the mere threat of whistleblowing can reduce fraud if managers in the team are sufficiently heterogeneous. In contrast, amnesty provisions are predicted to have no effect on behavior. Results from the laboratory experiment support many of the model‟s predictions and also shed light on behavior not predicted by theory. For example, contrary to theory, amnesty provisions have the desirable effect of reducing unreported fraud. *We would like to thank William Neilson and Christian Vossler for helpful comments. We would also like to thank the University of Tennessee for funding assistance. ** Corresponding author.
Adherence of oral streptococci to keratinized and nonkeratinized human oral epithelial cells

The ability of Streptococcus mutans, Streptococcus sanguis, Streptococcus mitis, and Streptococcus salivarius to adhere to keratinized versus nonkeratinized human oral epithelial cells was compared. S. mitis and S. salivarius exhibited significantly greater adherence to keratinized cells than to nonkeratinized cells. S. mutans and S. sanguis adhered equally well to either epithelial cell type. It is concluded that keratinization of epithelial cells may be a significant factor in the adherence of certain oral streptococci to the oral mucosa.
Feast and famine: a history of food and nutrition in Ireland 1500–1920

local organizations and the Ministry of Health struggled to contain the epidemic without support from the central government. In the course of this epidemic, the clock turned back, and many Peruvians came to accept that the achievement of good health is an individual matter, and not the responsibility of the state. Clearly argued and accessibly written, The return of epidemics presents a vivid case for state sponsored public health systems. The book's title refers to the feedback between poverty and disease a reading understandable when seen in the twentiethcentury context, yet it might be read differently, as referring to a return of epidemic crises after a period of stability or equilibrium in Peru's disease ecology. While much of the relevant social and economic history (less of the political) appears interwoven in the text, a broader introduction, explaining something of Peru's disease history before 1900, and setting out the path of the country's social, economic and political development across the twentieth century, would have provided useful background for an international readership.
Pellet morphology , culture rheology and lovastatin production in cultures of Aspergillus terreus

Pellet growth ofAspergillus terreusATCC 20542 in submerged batch fermentations in stirred bioreactors was used to examine the effects of agitation (impeller tip speed ut of 1.01–2.71 m s −1) and aeration regimens (air or an oxygen-enriched mixture containing 80% oxygen and 20% nitrogen by volume) on the fungal pellet morphology, broth rheology and lovastatin production. The agitation speed and aeration methods used did not affect the biomass production profiles, but significantly influenced pellet morphology, broth rheology and the lovastatin titers. Pellets of ∼1200 m initial diameter were reduced to a final stable size of ∼900 m when the agitation intensity was ≥600 rpm (ut ≥ 2.03 m s−1). A stable pellet diameter of ∼2500 m could be attained i n-enriched g ductivity e f dissolved o e specific e assage of t ar thinning c ©
Graph isomorphisms in discrete Morse theory

A discrete Morse function f on a graph G induces a sequence of subgraphs of G. In [1], the authors introduce a notion of equivalence between discrete Morse functions based on a sequence of homology groups of the corresponding subgraphs of G. In this paper, we use the homology sequence to study a new notion of equivalence between discrete Morse functions. This equivalence is based on the isomorphism type of the subgraphs of G. We count the number of equivalence classes on star graphs Sn and deduce an upper bound for the number of equivalence classes for a large collection of graphs.
SenseQ : Replying questions of Social Networks users by using a Wireless Sensor Network based on sensor relationships

Social Networks are a way of establishing communications with friends or family and a way of knowing what happens around us. However, there are not machines that provide users with information about their worries. What happens if a user wants to know if it is raining in a specific place at that moment? He needs to ask a person who is in that place at that moment. Why not take advantage of the Internet of Things to collect information in real time and answer users questions? The Internet of Things is a field that tries to measure everything by gathering data from sensors and interconnect different objects. Why not combine Social Networks and the Internet of Things? In this paper, we propose the development of a new system that will allow users to ask for information to a network of sensors through Social Networks, concretely in this case through Twitter. The system will have sensors registered by different users and this system that will be used to answer questions of other users. The system will be able to collect information of users sensors, process it, and use it to answer users questions through Social Networks. In order to gather the data from sensors and combine them, we propose three different types of relationships between sensors: neighboring relationship, familiar relationship and working relationship. Besides, we propose an architecture based on three layers: social layer, backend layer and object layer.
A Novel Hypothesis-Margin Based Method Incorporating Minimal-Redundancy Criterion for Feature Selection

Simba is a recently proposed algorithm based on hypothesis-margin for feature selection, it uses maximizing hypothesis-margin as a criterion for evaluating the effectiveness of a feature subset, in this way an effective feature subset can be efficiently obtained by employing the stochastic gradient ascent strategy. However, this algorithm still can not eliminate completely those redundant features. To overcome this drawback, in this paper, we propose a novel hypothesis-margin based method for feature selection incorporating minimal-redundant criterion (Rsimba). In Rsimba, after getting the weights of features by employing hypothesis-margin strategy, the mutual information criterion induced by clustering is introduced for removing those redundant features, in this way an effectively relevant feature subset can be efficiently obtained. Experiments show that the classification performance induced by Rsimba is better than that induced by Simba on all benchmark data sets.
A survey of UDP packet loss characteristics

Real time audio and video applications, though sensitive to packet loss and delay, do not require absolute reliability for transmission. Thus, understanding packet loss characteristics in the Internet, as well as in the MBone, can provide network researchers with an ability to design improved protocols for error control/concealment. This paper presents an analysis of real traffic measurements from the Internet/MBone, giving details of loss rates and packet loss characteristics of different receivers from different geographical regions. The analysis reveals that some receivers experience very high loss rate, of above 25%, and that a high percentage of these packet losses are burst losses of several consecutive packets.
Use of frequency‐modulated radiofrequency pulses in MR imaging experiments

With increasing field strength for whole‐body MR scanners there is a need for rf pulses of higher bandwidth to perform selective excitation or inversion. AM pulses will have to become shorter thus leading to an enormous requirement for the peak power of the power amplifier. To reduce these requirements the use of frequency modulation is investigated. The effect of pulses based on a linear frequency sweep on the spin system is analyzed by calculation and computer simulation. It turns out that the nonlinear phases induced by those pulses may compensate each other, that therefore spin‐echo experiments as usual in MR imaging may be performed, and that the required peak power may be reduced by up to a factor of 50. © 1986 Academic Press, Inc.
An empirical study of the antecedents and consequence of calculative commitment in B2B services

This research proposes and empirically analyses a model that considers switching costs and attractiveness of alternative service providers as antecedents to calculative commitment, and repurchase intentions as one of its consequences. Given that calculatively committed customers are important in fading relationships, we test these constructs amongst dissatisfied business services customers because research on the continuation of troubled business relationships is scarce. Data was collected online from 416 businesses using a key informant approach. Results support the contention that the antecedents of calculative commitment are attractiveness of alternative service providers and switching costs, specifically, benefit-loss costs, customer-service provider relationships costs and post-switching costs. Repurchase intentions was found to be a consequence of calculative commitment.
Empirical tight-binding force model for molecular-dynamics simulation of Si.

A scheme of molecular-dynamics simulation using the empirical tight-binding force model is proposed. The scheme allows the interatomic interactions involved in the molecular dynamics to be determined by first-principles total-energy and electronic-structure calculations without resorting to fitting experimental data. For a first application of the scheme we show that a very simple nearest-neighbor two-center empirical tight-binding force model is able to stabilize the diamond structure of Si within a reasonable temperature range. We also show that the scheme makes possible the quantitative calculation of the temperature dependence of various anharmonic effects such as lattice thermal expansion, temperature-dependent phonon linewidths, and phonon frequency shifts.
A System for Crowdsourcing Passive Mobile Network Measurements

In this poster, we build on top of the AntMonitor system and we extend it to add a new module for passive monitoring network performance on mobile devices (w/o middle server). We show that this design is efﬁ-cient yet powerful, in terms of the performance achieved (compared to alternatives today), realistic measurements (passive monitoring of actual trafﬁc on devices of real end-users), richness of information (ﬁne-grained measurements and rich contextual information available on the devices). We present the system design, a prelimi-nary evaluation, and example applications.