Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparative effectiveness of tepid sponging and antipyretic drug versus only antipyretic drug in the management of fever among children: a randomized controlled trial.

OBJECTIVE To compare the effectiveness of tepid sponging and antipyretic drug versus only antipyretic drug among febrile children. DESIGN Randomized controlled trial. SETTING Tertiary care hospital. PARTICIPANTS 150 children 6 mo - 12 yr age with axillary temperature 101F. INTERVENTION Tepid sponging and antipyretic drug (Paracetamol) (n=73) or only antipyretic drug (Paracetamol) (n=77). MAIN OUTCOME MEASURES Reduction of body temperature and level of comfort. RESULTS The reduction of body temperature in the tepid sponging and antipyretic drug group was significantly faster than only antipyretic group; however, by the end of 2 hours both groups had reached the same degree of temperature. The children in tepid sponging and antipyretic drug had significantly higher discomfort than only antipyretic group, but the discomfort was mostly mild. CONCLUSION Apart from the initial rapid temperature reduction, addition of tepid sponging to antipyretic administration does not offer any advantage in ultimate reduction of temperature; moreover it may result in additional discomfort.
Positron annihilation spectrum from the Galactic Centre region observed by SPI/INTEGRAL

The electron-positron annihilation spectrum observed by SPI/INTEGRAL during deep Galactic Centre region exposure is reported. The line energy (510.954±0.075 keV) is consistent with the unshifted annihilation line. The width of the annihilation line is 2.37 ± 0.25 keV (full width at half-maximum), while the strength of the ortho-positronium continuum suggests that the dominant fraction of positrons (94 ± 6 per cent) form positronium before annihilation. Compared to the previous missions, these deep INTEGRAL observations provide the most stringent constraints on the line energy and width. Under the assumption of an annihilation in a single-phase medium, these spectral parameters can be explained by a warm T e ∼ 7000 to 4 x 10 4 K gas with degree of ionization larger than a few 10 -2 . One of the widespread phases of the interstellar medium (ISM) - warm (T e ∼ 8000 K) and weakly ionized (degree of ionization ∼0.1) - satisfies these criteria. Other single-phase solutions are also formally allowed by the data (e.g. cold, but substantially ionized ISM), but such solutions are believed to be astrophysically unimportant. The observed spectrum can also be explained by annihilation in a multiphase ISM. The fraction of positrons annihilating in a very hot (T e ≥ 10 6 K) phase is constrained to be less than ∼8 per cent. Neither a moderately hot (T e ≥ 10 5 K) ionized medium nor a very cold (T e ≥ 10 3 K) neutral medium can make a dominant contribution to the observed annihilation spectrum. However, a combination of cold/neutral, warm/neutral and warm/ionized phases in comparable proportions could also be consistent with the data.
Under-frequency load shedding for power systems with high variability and uncertainty

Emergency load shedding for preventing frequency degradation is an established practice all over the world. The objective of load shedding is to balance load and generation. This paper presents a methodology to develop a reliable load shedding scheme, to prevent black-outs while maintaining stability in power systems with high variability and uncertainty under any abnormal condition. The technique proposes the sequence and conditions of applications of different load shedding schemes and islanding strategies. The effectiveness of the developed scheme was investigated by simulating different abnormal conditions in the power system of Sri Lanka.
A Qualitative Analysis of a Corporate Adventure Program

A Qualitative Analysis of a Corporate Adventure Learning Program Kim Molyneux Department of Recreation Management & Youth Leadership, BYU Master of Science Outdoor adventure learning (OAL) provides a unique environment to teach organizational change. Therefore, there is an implication these programs can be used to foster necessary specific skills such as leading change, innovation, and thriving in hostile environments to lead in the ever-changing corporate world. Little research, however, supports the efficacy of adventure learning in achieving specific outcomes. Skeptics suggested the benefits of OAL programs do not always generalize effectively from the outdoor experience to the workplace. This paper outlines how utilizing strategic skills and theory to conduct OAL programs are effective and impactful in the corporate world. The purpose of this study was to examine the perceptions and meaning of a based outdoor adventure learning program among corporate executives using qualitative data analysis (QDA).
Estimating Realized Heritability in Panmictic Populations

Narrow sense heritability (h2) is a key concept in quantitative genetics, as it expresses the proportion of the observed phenotypic variation that is transmissible from parents to offspring. h2 determines the resemblance among relatives, and the rate of response to artificial and natural selection. Classical methods for estimating h2 use random samples of individuals with known relatedness, as well as response to artificial selection, when it is called realized heritability. Here, we present a method for estimating realized h2 based on a simple assessment of a random-mating population with no artificial manipulation of the population structure, and derive SE of the estimates. This method can be applied to arbitrary phenotypic segments of the population (for example, the top-ranking p parents and offspring), rather than random samples. It can thus be applied to nonpedigreed random mating populations, where relatedness is determined from molecular markers in the p selected parents and offspring, thus substantially saving on genotyping costs. Further, we assessed the method by stochastic simulations, and, as expected from the mathematical derivation, it provides unbiased estimates of h2. We compared our approach to the regression and maximum-likelihood approaches utilizing Galton’s dataset on human heights, and all three methods provided identical results.
Eine Kurzskala zur Messung von Kontrollüberzeugung: Die Skala Internale-Externale-Kontrollüberzeugung-4 (IE-4)

Erhebungsinstrumente zur Erfassung von psychologischen Merkmalen wie beispielsweise Personlichkeit, Risikobereitschaft, Werte, Lebenszufriedenheit, Attraktivitat, Optimismus oder Intelligenz, werden immer haufiger in der Forschung eingesetzt. Neben der psychologischen Forschung, in der psychologische Merkmale traditionell im Zentrum des Interesses stehen, werden psychologische Merkmale ver-mehrt auch in anderen Forschungsbereichen erhoben, zum Beispiel in den Sozialwissenschaften, den Wirtschaftwissenschaften, den Ingenieurswissenschaften und den Gesundheitswissenschaften. Die Forscherinnen und Forscher der verschiedenen Disziplinen erwarten von der Erfassung dieser Merkmale in Umfragen, Studien und Experimenten sowie deren Implementierung in ihre Modelle eine bessere Deskription und Pradiktion wissenschaftlich und gesellschaftlich relevanter Prozesse und Phanomene.
Transition towards Sustainable Mobility: The Role of Instruments, Individuals and Institutions

Contents: Preface The complex challenge of transitions towards sustainable mobility - an introduction, Harry Geerlings, Yoram Shiftan and Dominic Stead Part I Concepts and Challenges: Transition management: a new opportunity for introducing more sustainable transport policies? , Harry Geerlings, Jasper Lohuis and Yoram Shiftan Transition management as a new policy making for sustainable mobility, Flor Avelino, Nanny Bressers and Rene Kemp Reflection on transition management: mobility policy between integration and differentiation, Bonno Pel Applying transition management in ongoing programmes and projects in the Netherlands: the case of Transumo and rush hour avoidance, Teije Gorris and Suzanne van den Bosch Short-term versus long-term dichotomies: applying transition management in the A-15 project, Nanny Bressers, Flor Avelino and Harry Geerlings. Part II Climate Change, Transport Energy Use and Emissions: Characterizing the impacts of uncertainty in the policy process: climate science, policy construction, and local governance decisions, Deb Niemeier, Thomas D. Beamish, Alissa Kendall, Ryken Grattet, Jonathan London, Carolyn de la Pena and Julie Sze Public acceptance of hydrogen technologies in transport: a review and reflection on empirical studies, Nicole Huijts, Eric Molin, Caspar Chorus and Bert van Wee Transport related CO2 emissions - deconstructing the trends, Yusak Susilo and Dominic Stead Modelling the potential transport CO2 mitigation impacts of available policy interventions, Robin Hickman, David Banister and Olu Ashiru. Part III The Role of Information in Policy-Making: The role of information contestability in evidence-based policy in planning and transport, Marcus Wigan Encouraging changes in travel behaviour towards more sustainable mobility patterns: the role of information, Anais Rocci Land use and transport information that matters, Marco te Brommelstroet and Luca Bertolini. Part IV Policy Evaluation: Modelling responses to congestion pricing in Tel-Aviv: an activity-based approach, Yoram Shiftan and Issa Zananiri Evaluation of transport external cost regulation of atmospheric pollution: an investigation using global sensitivity analysis, Hana Bruhova-Foltynova and Jan Bruha Modelling the influence of temporal and monetary constraints on activity participation, travel, consumption of goods, residential location, and work status: application in a land use interaction (LUTI) model, Dick Ettema, Theo Arentze and Harry Timmermans The policy implementation process for road pricing in the Netherlands, Diana Vonk Noordegraaf, Jan Anne Annema and Odette van de Riet. Epilogue: The role of instruments, individuals and institutions in promoting sustainable transport: concluding remarks, Dominic Stead, Harry Geerlings and Yoram Shiftan Bibliography Index.
Event Representations with Tensor-based Compositions

Robust and flexible event representations are important to many core areas in language understanding. Scripts were proposed early on as a way of representing sequences of events for such understanding, and has recently attracted renewed attention. However, obtaining effective representations for modeling script-like event sequences is challenging. It requires representations that can capture event-level and scenario-level semantics. We propose a new tensor-based composition method for creating event representations. The method captures more subtle semantic interactions between an event and its entities and yields representations that are effective at multiple event-related tasks. With the continuous representations, we also devise a simple schema generation method which produces better schemas compared to a prior discrete representation based method. Our analysis shows that the tensors capture distinct usages of a predicate even when there are only subtle differences in their surface realizations.
The University of Amsterdam at INEX 2006

We describe the University of Amsterdam's participation in the INEX 2006 Adhoc Track. We participated in all four Adhoc Track tasks, and report initial findings based on a single set of measure for all four tasks. Our main findings are the following. First, a complete element index outperforms a restricted index based on section-structure, albeit the dierences are small. Second, grouping elements per article does not lead to performance degradation, but may improve scores. Third, all restrictions of the "pure" element runs (by removing overlap, by grouping elements per article, or by selecting a single element per article) lead to some but only moderate loss of precision.
Automatic processing of broadcast audio in multiple languages

This paper addresses recent progress in LVCSR in multiple languages which has enabled the processing of broadcast audio for information access. At LIMSI, broadcast news transcription systems have been developed for seven languages. Automatic processing to access the content must take into account the specificities of audio data, such as needing to deal with the continuous data stream and an imperfect word transcription, and specificities of the language. Some near-term applications are audio data mining, structurization of audiovisual archives, selective dissemination of information and media monitoring.
A new time-projecting controller based on 3LP model to recover intermittent pushes

In this paper, we present a new walking controller based on 3LP model. Taking advantage of linear equations and closed-form solutions of 3LP, the proposed controller can project the state of the robot at any time during the phase back to a certain event for which, a discrete LQR controller is designed. After the projection, a proper control policy is generated by the expert discrete controller and used online. This projecting architecture reacts to disturbances with minimal delay and compared to discrete controllers, it provides superior performance in recovering intermittent external pushes. Further analysis of closed-loop eigenvalues and disturbance rejection shows that the proposed time-projecting controller has strong stabilization properties. Controllable regions also show that the projecting architecture covers most of the maximal controllable set of states. It is computationally much faster than model predictive controllers, but still optimal.
A lightweight dependency analyzer for partial parsing

In this paper, we present a novel approach to partial parsing that produces dependency links between words of a sentence. The partial parser called a lightweight dependency analyzer uses information encoded in supertags and hence can produce constituency-based as well as dependency-based analyses. The lightweight dependency analyzer has been used for text chunking, including noun and verb group chunking. We also present a proposal for a general framework for parser evaluation that is applicable for evaluating both constituency-based and dependency-based, partial and complete parsers. The performance results of the lightweight dependency analyzer on Wall Street Journal and Brown corpus using the proposed evaluation metrics are discussed.
Evaluation of Berlin Questionnaire Validity for Sleep Apnea Risk in Sleep Clinic Populations

Introduction: The Berlin questionnaire (BQ) is a common tool to screen for Obstructive Sleep Apnea (OSA) in the general population, but its application in the clinical sleep setting is still challenging. The aim of this study was to determine the specificity and sensitivity of the BQ compared to the apnea-hypopnea index obtained from polysomnography recordings obtained from a sleep clinic in Iran. Methods: We recruited 100 patients who were referred to the Sleep Disorders Research Center of Kermanshah University of Medical Sciences for the evaluation of suspected sleep-disorder breathing difficulties. Patients completed a Persian version of BQ and underwent one night of PSG. For each patient, Apnea-Hypopnea Index (AHI) was calculated to assess the diagnosis and severity of OSA. Severity of OSA was categorized as mild when AHI was between 5 and 15, moderate when it was between 15 and 30, and severe when it was more than 30. Results: BQ results categorized 65% of our patients as high risk and 35% as low risk for OSA. The sensitivity and the specificity of BQ for OSA diagnosis with AHI>5 were 77.3% and 23.1%, respectively. Positive predictive value was 68.0% and negative predictive value was 22.0%. Moreover, the area under curve was 0.53 (95% CI: 0.49 – 0.67, P=0.38). Discussion: Our findings suggested that BQ, despite its advantages in the general population, is not a precise tool to determine the risk of sleep apnea in the clinical setting, particularly in the sleep clinic population.
The Hypothesis of NMDA Receptor Hypofunction for Schizophrenia

Schizophrenia, a multifactorial mental disorder with polygenic inheritance as well as environmental influences, encompasses a characteristic group of symptoms and neurocognitive deficits. Cognitive function, a major determinant of quality of life and overall function in schizophrenia, contributes more to the prognosis of the disease than positive symptoms, such as delusions or hallucinations. Although its exact etiological mechanisms remain relatively unknown, extensive studies are ongoing to explore. Among them, one of the primary causal factors is dysfunction of the N-methyl-D-aspartate (NMDA)-type glutamate receptors. This article reviews the clinical limitations of current antipsychotics in treating the core symptoms of schizophrenia and the trend in the reconceptualization of the disease nature and treatment modalities. The NMDA receptor model plays a critical role in the revolution of pharmaceutical industry as a new set of drug targets in addition to those based on the traditional monoaminergic models is proposed. The evidence of NMDA receptor hypofunction in schizophrenia is accumulating from the investigations on the modulation of glutamatergic system, particularly the intrinsic NMDA/glycine site, through genetic research and various clinical trials. A group of ”NMDA-enhancing agents,” being used either as adjuncts to typical/atypical antipsychotics or as monotherapy, in schizophrenic patients, particularly those with refractory negative and cognitive symptoms, offer efficacy in preclinical and early clinical trials. Novel therapeutic agents acting as NMDA enhancers show promise as the next wave of drug development for schizophrenia.
An Example-Based Approach to Difficult Pronoun Resolution

A Winograd schema is a pair of twin sentences containing a referential ambiguity that is easy for a human to resolve but difficult for a computer. This paper explores the characteristics of world knowledge necessary for resolving such a schema. We observe that people tend to avoid ambiguous antecedents when using pronouns in writing. We present a method for automatically acquiring examples that are similar to Winograd schemas but have less ambiguity. We generate a concise search query that captures the essential parts of a given source sentence and then find the alignments of the source sentence and its retrieved examples. Our experimental results show that the existing sentences on the Web indeed contain instances of world knowledge useful for difficult pronoun resolution.
Amount-dependent isotopic fractionation during compound-specific isotope analysis.

The performance of a gas chromatography-combustion-isotope ratio mass spectrometry system (GC-C-IRMS) with respect to the dependence of delta(13)C values on the amount of sample is presented. Particular attention is paid to the localization of the amount-dependent isotopic fractionation within the system. Injection experiments with varying amounts of gases (CO(2), n-hexane, and toluene) revealed that neither the detector unit nor the combustion reactor, but rather the conditions in the split/splitless injector, contributed to this effect. Although optimization of injector parameters was performed and a reduction of this adverse effect from 3 to 1 per thousand was achieved, it was not possible to eliminate isotopic fractionation completely. Consequently, additional injector parameters have to be considered and adjusted to achieve injection conditions free of fractionation. For routine analysis of the compound-specific delta(13)C analysis of different biomarkers in many environmental samples, perfect optimization may not always be reached. Therefore, in order to prevent systematic errors in the measured delta(13)C values due to different sample concentrations, it is suggested that correction for the remaining unknown amount-dependent fractionation can be made by means of co-analyzing standards of varying analyte concentrations and known delta(13)C values. Residual overall amount-dependent isotope-fractionation can thus be corrected mathematically.
Temporal Dimensions in Rules Modelling

Typically legal reasoning involves multiple temporal dimensions. The contribution of this work is to extend LKIF-rules (LKIF is a proposed mark-up language designed for legal documents and legal knowledge in ESTRELLA Project [3]) with temporal dimensions. We propose an XML-schema to model the various aspects of the temporal dimensions in legal domain, and we discuss the design choices. We illustrate the use of the temporal dimensions in rules with the help of real life examples.
Cancer Therapy : Preclinical NEMO-Binding Domain Peptide Inhibits Constitutive NFk B Activity and Reduces Tumor Burden in a Canine Model of Relapsed , Refractory Diffuse Large B-Cell Lymphoma

Purpose: Activated B-cell diffuse large B-cell lymphoma (ABC-DLBCL) is an aggressive, poorly chemoresponsive lymphoid malignancy characterized by constitutive canonical NF-kB activity that promotes lymphomagenesis and chemotherapy resistance via overexpression of antiapoptotic NF-kB target genes. Inhibition of the canonical NF-kB pathway may therefore have therapeutic relevance in ABCDLBCL. Here, we set out to determine whether dogs with spontaneous DLBCL have comparative aberrant constitutive NF-kB activity and to determine the therapeutic relevance of NF-kB inhibition in dogs with relapsed, resistant DLBCL. Experimental Design: Canonical NF-kB activity was evaluated by electrophoretic mobility shift assays and immunoblot analyses, and NF-kB target gene expression was measured by quantitative real time PCR. Primary malignant canine B lymphocytes were treated with the selective IKK complex inhibitor NF-kB essential modulator-binding domain (NBD) peptide and evaluated for NF-kB activity and apoptosis. NBD peptide was administered intranodally to dogs with relapsed B-cell lymphoma and NF-kB target gene expression and tumor burden were evaluated preand post-treatment. Results:Constitutive canonical NF-kB activity and increased NF-kB target gene expression were detected in primary DLBCL tissue. NBD peptide inhibited this activity and induced apoptosis of primary malignant B cells in vitro. Intratumoral injections of NBD peptide to dogs with relapsed DLBCL inhibited NF-kB target gene expression and reduced tumor burden. Conclusions: This work shows that dogs with spontaneous DLBCL represent a clinically relevant, spontaneous, large animal model for human ABC-DLBCL and shows the therapeutic relevance of NF-kB inhibition in the treatment of ABC-DLBCL. These results have important translational relevance for ABCDLBCL treatment in human patients. Clin Cancer Res; 17(14); 4661–71. ’2011 AACR.
Foucault – en introduktion

Michel Foucault (1926–1984) var en av 1900-talets mest inflytelserika samhallsteoretiker. Hans tankande kring galenskap, makt, diskurs, kriminalitet, sanning, disciplin, styrning och sexualitet och .