Miracle-dz/UniFAR-FTUs huggingface dataset:
Isotropic Surface Remeshing Using Constrained Centroidal Delaunay Mesh

We develop a novel isotropic remeshing method based on constrained centroidal Delaunay mesh (CCDM), a generalization of centroidal patch triangulation from 2D to mesh surface. Our method starts with resampling an input mesh with a vertex distribution according to a user‐defined density function. The initial remeshing result is then progressively optimized by alternatively recovering the Delaunay mesh and moving each vertex to the centroid of its 1‐ring neighborhood. The key to making such simple iterations work is an efficient optimization framework that combines both local and global optimization methods. Our method is parameterization‐free, thus avoiding the metric distortion introduced by parameterization, and generating more well‐shaped triangles. Our method guarantees that the topology of surface is preserved without requiring geodesic information. We conduct various experiments to demonstrate the simplicity, efficacy, and robustness of the presented method.
Expression of the SM‐20 Gene Promotes Death in Nerve Growth Factor‐Dependent Sympathetic Neurons

Abstract: Sympathetic neurons undergo apoptosis when deprived of nerve growth factor (NGF). Inhibitors of RNA or protein synthesis block this death, suggesting that gene expression is important for apoptosis in this system. We have identified SM‐20 as a new gene that increases in expression in sympathetic neurons after NGF withdrawal. Expression of SM‐20 also increases during neuronal death caused by cytosine arabinoside or the phosphatidylinositol 3‐kinase inhibitor LY294002. In addition, SM‐20 protein synthesis is elevated in NGF‐deprived neurons compared with neurons maintained with NGF. Importantly, expression of SM‐20 in sympathetic neurons causes cell death in the presence of NGF. These results suggest that SM‐20 may function to regulate cell death in neurons.
Natural and synthetic oil phase transition microemulsions for ocular delivery of tropicamide: efficacy and safety

The objective of this work was to investigate the efficacy and safety of natural oils (castor oil and olive oil) based phase transition microemulsion systems for ocular delivery with reference to ethyl oleate systems. Tropicamide was used as model drug and was incorporated in the formulation at a concentration of 0.5% w/w. The phase transition systems comprised the oil, surfactant and water with the phase behavior depending on the concentration of water. The tested systems included microemulsion (ME), liquid crystalline system (LC) and coarse emulsion (EM). The efficacy of these systems was evaluated by monitoring the mydriatic response in comparison to drug solution containing polyvinylpyrrolidone (PVP). Ocular irritation was monitored by visual inspection and tear flow estimation. Drug release depended on the formulation type and viscosity. Thus LC systems produced the slowest release rates followed by the ME with the EM producing the largest release rate. The mydriatic response versus time plots showed biphasic effect with two maxima (MRmax) which verified the systemic absorption of the drug. Both ethyl oleate and olive oil based systems were more effective than the control with respect to the area under the mydriatic response profile. However, castor oil based systems were comparable to the control. With respect to ocular irritation castor oil based system were the least irritant followed by olive oil systems with ethyl oleate systems being the most irritant. The study thus introduced olive oil based phase transition systems for ocular drug delivery with lower irritation compared to the synthetic oil systems.
Adolescent girls' Anaemia Control Programme, Gujarat, India.

BACKGROUND & OBJECTIVE In June 2000, Adolescent Anaemia Control Programme was initiated as a pilot programme in Vadodara district of Gujarat covering over 69000 girls in over 426 schools. Programme strategy was to provide once weekly fixed day (Wednesday) supervised iron folic acid (IFA) supplements to all adolescent girls in Grade 8-12. Currently, programme covers 10 lakh schoolgirls and 2.6 lakh out of school girls with a compliance rate of over 90 per cent as reported by education department. This study was undertaken to institutionalize once a week IFA supplementation in the schools for adolescent girls with built in compliance monitoring in one district and scale up the programme from its learning to all the districts as feasible. METHODS Baseline survey for three areas of Vadodara district, tribal, rural and urban from 10 schools each was conducted to collect data for anaemia prevalence. Education Inspectors were assigned responsibility to supervise and motivate teachers to try out innovative ideas to promote the programme. Simultaneously anganwadi workers of urban Vadodara were motivated to initiate IFA supplementation for out of schoolgirls on similar strategy. After approximately 17 months of intervention, impact study was conducted in the same 30 schools in November 2001 to obtain levels of anaemia and some of the paired data from the students who were part of the baseline study. Study also included knowledge and practices of the adolescent girls with reference to their dietary habits and package of intervention included nutrition education through schools by providing information and education material prepared by the government. RESULTS Baseline study had shown around 75 per cent anaemia prevalence, which was similar in all the three areas. Level of serum ferritin was also low. Impact evaluation showed reduction in anaemia prevalence by 21.5 per cent that is, from 74.7 per cent to 53.2 per cent (P<x0.05). Further improvement in Hb was recorded among 80 per cent girls. Pre- and post-intervention also showed improvement in serum ferritin value. Programme is now scaled up to cover 10 lakh schoolgirls and 2.6 lakh out of school girls in the State. Out of schoolgirls is only small fraction of total out of schoolgirls in the state. Data on dietary and nutritional related knowledge and practices did not show significant changes among schoolgirls. Retention of messages specified in IEC material was not satisfactory. INTERPRETATION & CONCLUSION Supervised, once a week IFA supplementation to adolescent girls through institutions specially, schools was found to be an effective intervention to reduce anaemia and was scalable within the system. The experience to educate the girls on dietary behaviour has not been satisfactory and covering all out of school girls is still a challenge to the success of anaemia control.
Design of innovative therapeutics for pharmacoresistant epilepsy: Challenges and needs

Effective therapy for pharmacoresistant epilepsy is an unmet clinical need. Pharmacologically, there are two logical approaches: super‐antiictogenic drugs (SAIDs) or antiepileptogenic agents. However, can either of these agents be successfully designed and developed? Designing SAIDs or antiepileptogenics will require applying the techniques of twenty‐first century drug design to this ancient “sacred disease. ” Before this task can be effectively realized, five fundamental needs will first have to be addressed: need for antiepileptogenic drug targets, need for druggable targets for SAIDs, need for new drug molecule platforms, need for new and relevant animal models, and need for innovative funding strategies.
Emotions analysis techniques: Their application in the identification of criteria for selecting suitable Open Educational Resources (OERs)

Emotion analysis is a key variable in textual analysis, namely that which focuses on detecting, separating or extracting information related to human attitudes and feelings-such as opinions or value judgments. This research paper aims to identify through a combination of techniques the human feelings and emotions of university students when selecting suitable (Open) Educational Resources in a Systems Engineering degree course. Although this research is only currently in its developmental stage, it provides some conclusions about the state of the art as well as details of future works that will be carried out in the field of emotion analysis in an online environment.
Effects of Physical Exercise Intervention on Motor Skills and Executive Functions in Children With ADHD: A Pilot Study

Objective: This study examined the effect of a 12-week table tennis exercise on motor skills and executive functions in children with ADHD. Method: Fifteen children with ADHD received the intervention, whereas 15 children with ADHD and 30 typically developing children did not. The Test of Gross Motor Development–2, Stroop, and Wisconsin Card Sorting Test (WCST) were conducted before and after the intervention. Results: After the intervention, the ADHD training group scored significantly higher in the locomotor as well as object-control skills, Stroop Color–Word condition, and WCST total correct performance compared with the ADHD non-training group, and we noted improvements in the locomotor as well as object-control skills, Stroop Color–Word condition, and three aspects of the WCST performances of the ADHD training group over time. Conclusion: A 12-week table tennis exercise may have clinical relevance in motor skills and executive functions of children with ADHD.
Simple Power Control for Sensorless Induction Motor Drives Fed by a Matrix Converter

This paper presents a new and simple method for sensorless control of matrix converter drives using a power flowing to the motor. The proposed control algorithm is based on controlling the instantaneous real and imaginary powers into the induction motor. To improve low-speed sensorless performance, the nonlinearities of a matrix converter drive such as commutation delays, turn-ON and turn-OFF times of switching devices, and on-state switching device voltage drop are modeled using a PQ power transformation and compensated using a reference power control scheme. The proposed sensorless control method is applied for the induction motor drive using a 3 kW matrix converter system. Experimental results are shown to illustrate the feasibility of the proposed strategy.
Designing TramMateña context-aware mobile system supporting use of public transportation

We describe the design of a mobile information service that provides users with a route-planning tool for the tram-based public transport system of Melbourne, Australia. The design sketches for TramMate represent early iterations of an ongoing design process based on data from field studies on the use of transportation by business employees who, during a typical workday, have to attend appointments at different physical locations. TramMate supports this activity by keeping track of contextual factors such as the userís physical location, upcoming appointments, and real-time travel information. The design is integrated with an electronic calendar and alerts the user when it is necessary to commence the journey.
Determining optimal power, location and direction of transmitters using a genetic algorithm

Electromagnetic field pollution caused by various human-made sources can pose a health hazard, especially in urban and dense populated areas. Many independent service providers install new electromagnetic sources (transmitters) usually without mutual coordination. In this paper an investigation is presented for adjustment of transmitters' parameters (e.g. location, direction, power) to minimize a health hazard caused by the electromagnetic radiation while in the same time satisfy service availability (minimal reception of electromagnetic field strength for each provider). In this research two transmitters with a different nonuniform radiation diagrams were positioned within the observed area and their parameters were adjusted (power, direction, position) taking into account electromagnetic field constraints in areas where people reside. Using here proposed GA aided method for transmitters' parameter adjustment promising results were achieved.
A 1.62/2.7/5.4Gbps clock and data recovery circuit for DisplayPort 1.2

In this paper, a clock and data recovery (CDR) circuit that supports triple data rates of 1.62, 2.7 and 5.4Gbps for DisplayPort 1.2 standard is described. The proposed CDR circuit employs a dual-loop architecture that includes a phase-locked loop and a frequency-locked loop. The circuit with a half-rate phase detector has a triple-mode voltage-controlled oscillator (VCO) which changes the operating frequency by 3bit code. The prototype chip is designed and verified using a 65nm CMOS technology. The recovered-clock jitter with the data rates of 1.62/2.7/5.4Gbps at 231-1 PRBS is measured to 7/5.6/4.7psrms, respectively, while consuming 11mW with a 1.2V supply.
Triglycerides and atherogenic dyslipidaemia: extending treatment beyond statins in the high-risk cardiovascular patient

Although statins significantly decrease the incidence of cardiovascular disease (CVD), residual CVD risk remains high. This may partly be due to uncorrected atherogenic dyslipidaemia. The driving force behind atherogenic dyslipidaemia is hypertriglyceridaemia, which results from hepatic oversecretion and/or hypocatabolism of triglyceride-rich lipoproteins, and is typical of type 2 diabetes and metabolic syndrome. Persistent atherogenic dyslipidaemia in patients treated with a statin according to low-density lipoprotein-cholesterol goals may be corrected with niacin, fibrates or n–3 fatty acids. Clinical trial evidence to inform best practice is limited, but new data support adding fenofibrate to a statin. A consistent feature of fibrate clinical trials is the specific benefit of these agents in dyslipidaemic patients and the improvement in diabetic retinopathy with fenofibrate. Ongoing clinical trials may provide good evidence for adding niacin to a statin. Low-dose n–3 fatty acids could be used routinely after a myocardial infarction, but the value of higher doses of n-3 fatty acids in reducing CVD risk remains to be demonstrated.
Transcriptional analysis of virulence‐related genes in enterococci from distinct origins

Aims: The role of enterococci in food fermentation and as probiotics counteracts with their increasing importance as human pathogens. Over the years, several virulence factors have been described, mainly in clinical strains but also in food isolates. However, differential expression of such traits may modulate the pathogenic potential of the harbouring enterococci. To further unravel such differential response, this study aims to identify environmental cues responsible for triggering the expression of virulence‐related genes.
Using Designed Structure of Visual Content to Understand Content-Browsing Behavior

Studies on gaze analysis have revealed some of the relationships between viewers’ gaze and their internal states (e.g., interests and intentions). However, understanding content browsing behavior in uncontrolled environments is still challenging because human gaze can be very complex; it is affected not only by viewers’ states but also by the spatiosemantic structures of visual content. This study proposes a novel gaze analysis framework which introduces the content creators’ point of view to understand the meaning of browsing behavior. Visual content such as web pages, digital articles and catalogs are comprised of structures intentionally designed by content creators, which we refer to as designed structure. This paper focuses on two design factors of designed structure: spatial structure of content elements (content layout), and their relationships such as “being in the same group”. The framework was evaluated with an experiment involving 12 participants, wherein the participant’s state was estimated from their gaze behavior. The results from the experiment show that the use of design structure improved estimation accuracies of user states compared to other baseline methods. key words: eye tracking, catalog browsing, user states, content design
Encoding of correlated observations

An important class of engineering problems involves sensing an environment and making estimates based on the phenomena sensed. In the traditional model of this problem, the sensors' observations are available to the estimator without alteration. There is . growing interest in {\em distributed} sensing systems in which several observations are communicated to the estimator over channels of limited capacity. The observations must be separately encoded so that the target can be estimated with minimum distortion. Two questions are addressed for a special case of this problem wherein there are two sensors which observe noisy data and communicate with a single estimator: 1) if the encoder is unlimited in complexity, what communication rates and distortions can be achieved, 2) if the encoder must be a quantizer (a mapping of a single observation sample into a digital output), how can it be designed for good performance? The first question is treated by the techniques of information theory. It is proved that a given combination of rates and distortion is achievable if there exist degraded versions of the observations that satisfy certain formulas. The second question is treated by two approaches. In the first, the outputs of the quantizers undergo a second stage of encoding which exploits their correlation to reduce the output rate. Algorithms which design the second stage are presented and tested. The second approach is based on the {\em distributional distance}, a measure of dissimilarity between two probability distributions. An algorithm to modify a quantizer for increased distributional distance is derived and tested.
Cognitive aspects of prejudice

Summary The aim of this paper was to stress the importance of the adaptive cognitive functioning of man in the causation of prejudice. It was felt that this approach has the merits of economy, credibility and testability of explanation which are not always shared by views seeking the psychological causes of intergroup tensions in the evolutionary past of the species or in unconscious motivation. Three cognitive processes were considered from the point of view of their relevance to the genesis of prejudice in an individual: categorization, assimilation, and search for conceptual coherence. Though the paper was not concerned either with discussing ways to reduce prejudice or with outlining in any detail designs for future research, it is my belief that the general approach adopted here has implications, both for social action and for research, which have not been as yet consistently and fully taken into account.
Circulating chemokine (C‐X‐C Motif) receptor 5+CD4+ T cells benefit hepatitis B e antigen seroconversion through IL‐21 in patients with chronic hepatitis B virus infection

Given the clinical significance of hepatitis B e antigen (HBeAg) seroconversion in chronic hepatitis B virus (HBV) infection, it is critical to elucidate the mechanisms regulating this process. In the present study, we found that the frequency of circulating chemokine (C‐X‐C motif) receptor 5 (CXCR5)+CD4+ T cells was higher in patients who had achieved HBeAg seroconversion in both cross‐sectional (P < 0.001) and longitudinal (P = 0.009) studies. These cells were able to produce a significantly higher level of intracellular interleukin 21 (IL‐21) after stimulation with HBV peptides in patients with telbivudine‐induced HBeAg seroconversion (P = 0.007). Furthermore, sorted CXCR5+CD4+ T cells from HBeAg seroconverters boosted a higher frequency of antibody against hepatitis B e antigen (anti‐HBe)‐secreting B cells in coculture assay (P = 0.011). Of note, the increase in frequency of anti‐HBe‐secreting B cells was abrogated by soluble recombinant IL‐21 receptor‐Fc chimera (P = 0.027), whereas exogenous recombinant IL‐21 enhanced this effect (P = 0.043). Additionally, circulating CXCR5+CD4+ T cells shared similar phenotypic markers, and were positively correlated in frequency with, splenic follicular T helper cells. Conclusion: Circulating CXCR5+CD4+ T cells, by producing IL‐21, may have a significant role in facilitating HBeAg seroconversion in patients with chronic HBV infection. (Hepatology 2013;58:1277–1286)
Resampling of scanned imagery for rectification and registration

Spacecraft, aircraft, and seacraft are common free-moving platforms for the scanning of visible-light, radar, and sonar imagery. The motion of these platforms during scanning dictates image interior geometry. Hence such imagery is significantly different to that of the conventional frame-camera. It is explained why knowledge of platform motion is essential in scanned image resampling for rectification of geometric distortion. An unusual parameterization of motion is used to model scanner trajectory efficiently as a kinematic chain. Using this parameterisation, a new technique is proposed for determining whether a 3-D scene point lies within the frustum of a geometrically distorted image pixel. This inclusion test is important if the inverse mapping approach to image transformation is used for rectification. <<ETX>>
Renewable energy micro-grid power system for isolated communities

Technological advancement in the renewable energy industry is increasing the feasibility of incorporating renewable energy sources into the power systems of isolated communities. Previous studies have demonstrated how renewable energy resources can be incorporated into remote area power systems, in order to reduce operating costs and harmful emissions. The variable nature of renewable resources, however, is still an obstacle that needs be overcome in order to provide a robust power system using solely renewable energy technology. Research on optimising power systems reliability, has led to multiple methods for improving the design of robust renewable energy systems. This paper proposes a stand-alone power system that uses wind and solar energy, as well as a hydrogen fuel cell back up supply. The energy sources are combined with specific control techniques in order to totally eliminate the need for a diesel generator. A requirement of this proposal is that all major elements be commercially available.
Hof1 and Rvs167 Have Redundant Roles in Actomyosin Ring Function during Cytokinesis in Budding Yeast

The Hof1 protein (Homologue of Fifteen) regulates formation of the primary septum during cytokinesis in the budding yeast Saccharomyces cerevisiae, whereas the orthologous Cdc15 protein in fission yeast regulates the actomyosin ring by using its F-BAR domain to recruit actin nucleators to the cleavage site. Here we show that budding yeast Hof1 also contributes to actin ring assembly in parallel with the Rvs167 protein. Simultaneous deletion of the HOF1 and RVS167 genes is lethal, and cells fail to assemble the actomyosin ring as they progress through mitosis. Although Hof1 and Rvs167 are not orthologues, they both share an analogous structure, with an F-BAR or BAR domain at the amino terminus, capable of inducing membrane curvature, and SH3 domains at the carboxyl terminus that bind to specific proline-rich targets. The SH3 domain of Rvs167 becomes essential for assembly of the actomyosin ring in cells lacking Hof1, suggesting that it helps to recruit a regulator of the actin cytoskeleton. This new function of Rvs167 appears to be independent of its known role as a regulator of the Arp2/3 actin nucleator, as actin ring assembly is not abolished by the simultaneous inactivation of Hof1 and Arp2/3. Instead we find that recruitment to the bud-neck of the Iqg1 actin regulator is defective in cells lacking Hof1 and Rvs167, though future studies will be needed to determine if this reflects a direct interaction between these factors. The redundant role of Hof1 in actin ring assembly suggests that the mechanism of actin ring assembly has been conserved to a greater extent across evolution than anticipated previously.