Miracle-dz/UniFAR-FTUs huggingface dataset:
Low-skilled workers in the "Knowledge Based-Economy": The Case of the Pharmaceutical Sector in France and Belgium

When social sciences study the workforce in the “knowledge economy”, they focus on the most highly skilled workers (managers and professionals). This article addresses the issue of the role and the employment conditions of low-skilled workers in the knowledge industries. How can we explain the persistence of low-skilled workers and bad jobs in high-tech sectors? And do the workers at the bottom of the hierarchy take advantage of working in a knowledge-based sector? From a collective survey conducted in the pharmaceutical sector (ethnographic surveys in production plants and drug distribution centers), we show that in this sector low-skilled workers (mainly women) are confined to low status jobs, with poor evolution prospects coupled with a growing use of temporary contracts. Although they manipulate high-tech products (drugs), low-skilled workers do not enjoy better working conditions than low-skilled workers in other industrial sectors. And we could even make the hypothesis that the situation of low skilled workers is even less enviable because they have to comply with the specific regulations of the pharmaceutical sector to guarantee the continuity of health care and safety; constraints that necessarily result in highly flexible schedules and variable work intensity.
The application of resonance frequency measurements to study the stability of titanium implants during healing in the rabbit tibia.

The aim of this investigation was to measure the resonance frequency of a number of implants placed in the rabbit tibia at insertion and at predetermined periods thereafter and to correlate the results with histomorphometric measurements made when the animals were sacrificed. Ten mature New Zealand White rabbits were used in the study. Two c.p. threaded titanium implants were placed in the right tibia of each animal. Resonance frequency measurements were made by screwing a small transducer onto a standard abutment mounted on each fixture. Measurements were repeated with the transducer oriented perpendicular and parallel to the long axis of the tibia for all proximal implants 14 and 28 days after placement and in 6 implants additionally at 42, 56, 93, 122 and 168 days after which all animals were sacrificed. Histomorphometric analysis comprised 2 parts; measurement of bone-implant contact area and height. A significant increase in resonance frequency was observed after 14 (405 Hz, +/- 234 Hz) and 28 (658 Hz, +/- 332 Hz) days. The increase in resonance frequency levelled after approximately 40 days and little further change was observed. The variation in bone-implant contact area was relatively small (1.8-4.9 mm2) and the range of bone-implant contact heights was also narrow (-1.5 (-)+ 1.5 mm). Values for resonance frequencies plotted against contact area and height were grouped around 10 kHz. In conclusion, it was shown that resonance frequency measurements can be made at placement and during healing in vivo and changes may be related to the increase in stiffness of an implant in the surrounding tissues.
Clinical Sensitivity of Cystic Fibrosis Mutation Panels in a Diverse Population

Infants are screened for cystic fibrosis (CF) in New York State (NYS) using an IRT‐DNA algorithm. The purpose of this study was to validate and assess clinical validity of the US FDA‐cleared Illumina MiSeqDx CF 139‐Variant Assay (139‐VA) in the diverse NYS CF population. The study included 439 infants with CF identified via newborn screening (NBS) from 2002 to 2012. All had been screened using the Abbott Molecular CF Genotyping Assay or the Hologic InPlex CF Molecular Test. All with CF and zero or one mutation were tested using the 139‐VA. DNA extracted from dried blood spots was reliably and accurately genotyped using the 139‐VA. Sixty‐three additional mutations were identified. Clinical sensitivity of three panels ranged from 76.2% (23 mutations recommended for screening by ACMG/ACOG) to 79.7% (current NYS 39‐mutation InPlex panel), up to 86.0% for the 139‐VA. For all, sensitivity was highest in Whites and lowest in the Black population. Although the sample size was small, there was a nearly 20% increase in sensitivity for the Black CF population using the 139‐VA (68.2%) over the ACMG/ACOG and InPlex panels (both 50.0%). Overall, the 139‐VA is more sensitive than other commercially available panels, and could be considered for NBS, clinical, or research laboratories conducting CF screening.
Robust time and phase synchronization for continuous phase modulation

A novel joint timing and phase-recovery technique is proposed for continuous phase modulation (CPM) systems based on Kalman filtering and an approximate representation of CPM signals with nonorthogonal exponential expansions (nOEE). Compared with existing techniques, the proposed synchronizer requires a less complex front-end processor, and can achieve reliable acquisition performance with a shorter preamble. The asymptotic stability and convergence of the proposed synchronizer is analyzed, including the effect of statistical channel-modeling errors on the convergence characteristics. The selection of suboptimal nOEEs and the design of triple-initialized Kalman filters are also discussed. Both theoretical and simulation results show that the proposed synchronizer is robust in acquiring and tracking both the time shift and the phase offset on either time-invariant or time-variant channels
Human Antigen R Binding and Regulation of SOX2 mRNA in Human Mesenchymal Stem Cells

Since 2005, sex determining region y–box 2 (SOX2) has drawn the attention of the scientific community for being one of the key transcription factors responsible for pluripotency induction in somatic stem cells. Our research investigated the turnover regulation of SOX2 mRNA in human adipose-derived stem cells, considered one of the most valuable sources of somatic stem cells in regenerative medicine. Mitoxantrone is a drug that acts on nucleic acids primarily used to treat certain types of cancer and was recently shown to ameliorate the outcome of autoimmune diseases such as multiple sclerosis. In addition, mitoxantrone has been shown to inhibit the binding of human antigen R (HuR) RNA-binding protein to tumor necrosis factor-α mRNA. Our results show that HuR binds to the 3′-untranslated region of SOX2 mRNA together with the RNA-induced silencing complex miR145. The HuR binding works by stabilizing the interaction between the 3′-untranslated region and the RNA-induced silencing complex. Cell exposure to mitoxantrone leads to HuR detachment and the subsequent prolongation of the SOX2 mRNA half-life. The prolonged SOX2 half-life allows improvement of the spheroid-forming capability of the adipose-derived stem cells. The silencing of HuR confirmed the above observations and illustrates how the RNA-binding protein HuR may be a required molecule for regulation of SOX2 mRNA decay.
The impact of Quality Maintenance Pillar of TPM on manufacturing performance

The purpose of this paper is to demonstrate the contributions of Quality Maintenance (QM) Pillar of TPM approach in improving the product quality in a food industry manufacturing potato chips. QM Pillar is an important initiative of TPM methodology which aims to give customer delight through defect free manufacturing. The effective TPM implementation enhances production efficiency with an ultimate aim of attaining zero breakdowns, zero losses and zero defects. The focus of QM Pillar is on eliminating non-conformances in a systematic manner and maintaining equipment to produce high quality products. The QM pillar activities in the industry remained successful in reducing the customer complaints and regulatory complaints to zero. Also, considerable reduction in number of major defects occurred and leakage problems reduced from 1.20% to 0.27%. The QM pillar targets are achieved successfully by the industry such as sustaining customer complaints at zero, reduce in-process defects by 83% and reduce cost of quality by 46%.
Transcutaneous oxygen pressure measurements in type I diabetic patients for early detection of functional diabetic microangiopathy

Abstract Seventy‐six type I diabetic patients free of peripheral artery disease and 82 age‐matched healthy volunteers were studied by means of transcutaneous oxygen pressure measurements. Two transcutaneous probes were attached to the skin at the subclavian region and at the supramalleolar region. Basal transcutaneous oxygen pressure values and values during breathing of 5 and 10 1 O2 min‐1, the rate of rise of oxygen pressure and the time required from the beginning of the oxygen pressure increase to the achievement of its maximum were recorded, and a regional perfusion index was calculated.
Semi-Automatic Road Extraction Algorithm from IKONOS Images Using Template Matching

This paper describes the development of a semi-automatic road extraction algorithm. The algorithm works as follows: First, a user provides an initial road seed per each road segment in the image. Next, orientation of the road seed is calculated automatically by applying Burns line extraction algorithm. A road template is then formed around the road seed and a road segment is extracted automatically through template matching. For template matching, an adaptive least square matching algorithm was used. This algorithm puts weights on road central line parts and postulates that the relationship between template and target windows can be modeled by similarity transformation. This algorithm also assumes that template and target windows have only small differences in brightness values. A 1m resolution IKONOS image over Seoul area was used for this algorithm test. The algorithm extracted road central lines in any orientation and with moderate curvature successfully, after road seeds were given from a user. Current limitations are that the algorithm may not work on the road cast by shadow and that a user must select valid road seeds on road central lines since the algorithm itself can not judge the validity of input seeds. These limitations are currently being examined. The contribution of this paper is that it showed template matching, instead of the well known “snake”, could be used for road extraction.
Impact of Load Shifting on the Profit of Electricity Retailer based on Demand Response and Risk Management

This paper aims to describe the role of electricity retailer in power market for persuading consumer to shift their loads. It presents the influence of load shifting on retailer profit and risk management in market environment. In this problem, retailer participates in bilateral contract, also stochastic programming is used to manage the uncertainties of pool prices and elasticity of consumer. It shows that by participating retailer in market contract, the retailer profit will be changed. This paper also analyzes the consumer behavior when the load is shifted from the time with high price to the time with low price. The tariff of demand response program used in this paper is Time of use pricing for the periods of week. Risk Measuring is done by Value at Risk (VaR) and Conditional Value at Risk (CVaR) in this study.
Cyber Public Relations (E-PR) dalam Brand Image Wardah Kosmetik dengan Pedekatan Mixed Method

Di tengah pesatnya perkembangan teknologi informasi dan komunikasi saat ini, praktisi public relations dituntut mampu memanfaatkan media internet (cyber public relations) dalam rangka mempromosikan produk dan sekaligus membangun brand image perusahaan. Sebagai produk kosmetik, Wardah telah melakukan aktivitas cyber public relations sebagai sarana pemasaran bagi produk-produk kosmetiknya. Selain itu, aktivitas cyber public relations juga bertujuan agar brand image Wardah semakin melekat dalam benak konsumen dan bisa dikenal lebih luas lagi. Penelitian ini bertujuan guna mengetahui bagaimana pengaruh cyber public relations terhadap brand image Wardah dalam benak para konsumennya. Penelitian ini menggunakan pendekatan mixed method. Penelitian diawali dengan pengumpulan data dan analisis kuantitatif, kemudian dilanjutkan dengan pengumpulan data dan analisis kualitatif. Hasil penelitian kualitatif tersebut digunakan untuk memberi penjelasan lebih lanjut mengenai fenomena yang belum dijelaskan berdasarkan hasil penelitian kuantitatif. Hasil penelitian ini menunjukkan bahwa aktivitas cyber public relations yang dilakukan oleh Wardah kosmetik berpengaruh secara signifikan terhadap brand image Wardah. Sementara hasil penelitian kualitatif menunjukkan bahwa hanya variabel situs pencari online dan media sosial yang berhubungan dengan aktivitas cyber public relations Wardah. Kata Kunci: Cyber public relations, brand image, wardah kosmetik, In the midst of rapid development of information and communication technology, public relations practitioners are required to take advantage of internet media (cyber public relations) in order to promote products and simultaneously build the company's brand image. As a cosmetic product, Wardah has been doing cyber public relations activities as a marketing tool for its cosmetic products. In addition, Wardah cyber public relations activities are also aims to make Wardah brand image more embedded in the minds of consumers and can be known more widely. This study aims to determine how the influence of cyber public relations toward Wardah’s brand image in the minds of its customers. This research uses mixed method approach. The research begins with data collection and quantitative analysis, followed by data collection and qualitative analysis. The results of qualitative research are used to provide further explanation of the phenomena that have not been described based on the results of quantitative research. The results of this study indicate that cyber public relations activities conducted by Wardah cosmetics significantly influence Wardah’s brand image. Meanwhile, the results of qualitative research indicate that only the variables of online search engine and social media related to Wardah’s cyber public relations activities. Keywords : Cyber public relations, brand image, wardah cosmetics,
Retailers' Use of Shipping Cost Strategies: Free Shipping or Partitioned Prices?

The Internet has radically reduced the cost of collecting and distributing information. Consequently, researchers initially predicted that the resulting price transparency would drive prices toward a single market price. However, this has largely not happened, partly because retailers use shipping costs to make prices less comparable. Using data on 517,048 offers of 895 retailers from a leading European price comparison site, we show that retailers pursue two different shipping cost strategies. Both strategies lead to higher gross product prices, which are the sum of net product price and shipping costs and thus try to capture consumer surplus. These strategies are conflicting, however, and target different consumer segments: Some retailers charge high shipping costs and thereby try to exploit consumers' biased perceptions of partitioned prices, while other retailers offer "free shipping" to attract consumers and exploit their so-called zero-risk bias. Consumers realize the lowest gross product prices by ordering at retailers that charge moderate shipping costs.
Power to the People!: European Perspectives on the Future of Electric Distribution

Implementing smart grids is central to the transition to a low-carbon economy, and DSOs are key players in this transition. A far-reaching change-one could say a revolution-in power systems is indeed ongoing; designing and implementing smart grids is not an option but an absolute necessity. If we do not do it, or if we do it too slowly, we will face major problems. To prepare, European DSOs are massively investing in R&D and demonstration projects in cooperation with the information communications technology (ICT) industry, acquiring the knowledge and skills needed to adapt and lead. Smart grids have the potential to benefit the whole value chain, but the market model must be defined. Whatever the preferred model, DSOs will have a key role to play as market enablers. DSOs will be responsible for setting up the playing field for retailers and aggregators so that it works for the benefit of customers. DSOs will increasingly act as local system operators. Well-organized active distribution system management will make it possible to reduce the investments needed to host renewable energy sources and electric vehicle charging stations and will guarantee security and quality of supply. Enhancing the “smartness” of distribution grids is not free of charge. It will require significant capex on the DSO side, while the benefits from those investments will accrue throughout the entire value chain. The development of business models, with the strong support of policy makers and regulators, is necessary to ensure that all parties share the risks, costs, and benefits of smart grids. Bringing smart grids from vision to reality will only happen if smart regulation is introduced. Last but not least, a key objective of European DSOs is to make sure that the new solutions that will be implemented are designed to benefit all customers.
Broad span of supply chain integration: theory development

PurposeThe purpose of this paper is to understand how theoretical lenses have been used to analyze the supply chain integration (SCI) theory. Furthermore, this paper elaborates theories derived from SCI research, in the form of propositions and a framework to explain the concept of the broader span of SCI.Design/methodology/approachThis paper is based on a systematic review of 194 research articles from Q1 to Q4 international journals over the period 1980–2017. Issues are explored under the integration keywords: “supply chain integration,” “internal integration,” “supplier integration,” “customer integration,” “third party logistics integration” and “logistics service provider integration. ”FindingsConceptually, SCI can be interpreted as a span that illustrates the internal integration of the focal organization, and the integration of the focal organization with suppliers, logistics service providers (LSPs) and customers. However, the result from the systematic literature review shows the SCI’s span still neglects LSPs. Based on that gap, a resource-based view (RBV) integrated with the resource dependence theory (RDT) is used to propose a broader SCI span that consists of internal, supplier, LSP and customer. Using both theories, this paper conceptualizes resources, dependence and uncertainty as the antecedents of the broader span of SCI.Originality/valueThis paper provides a theoretical contribution that integrates the RBV and RDT as a basis for developing the broader span of SCI.
Qualitative Review of Object Recognition Techniques for Tabletop Manipulation

This paper provides a qualitative review of different object recognition techniques relevant for near-proximity Human-Robot Interaction. These techniques are divided into three categories:2D correspondence, 3D correspondence and non-vision based methods. For each technique an implementation is chosen that is representative of the existing technology to provide a broad review to assist in selecting an appropriate method for tabletop object recognition manipulation. For each of these techniques we give their strengths and weaknesses based on defined criteria. We then discuss and provide recommendations for each of them.
Semantic Recommendation of Information Sources for Lifelong Learning

Lifelong learning LLL has been debated in educational environments for more than a decade, but with the proliferation of mobile and wireless communication technologies and pervasiveness of educational environments, it has penetrated into our everyday lives and changed our perception on formal education. If we accept that LLL will have a bigger role in traditional education, and remove barriers between formal and informal learning, then we may open a range of new possibilities for modern learners, who decide what, when, why and how they wish to learn. In this paper we address the problem of choosing suitable learning sources in various situations we may encounter in LLL. We propose a semantic recommendation of learning sources, based on OWL/SWRL enabled computations for the purpose of supporting learners in lifelong learning environments. We use the example of learners in the healthcare domain in order to demonstrate both: the availability of online information and learning sources which support lifelong learning in healthcare, and the way we can address the needs of individual learners who are in a situation to learn informally. We focus on OWL/SWRL enabled computations because they a secure semantic interpretation of environments where lifelong learning takes place and b guarantee reasoning which results in recommendations of suitable learning sources in a particular situation in LLL.
Pengaruh Celebrity Endorser Hamidah Rachmayanti Terhadap Keputusan Pembelian Produk Online Shop MAYOUTFIT Di Kota Bandung

Utilization of internet among modern society today is the use of social media. Of the many social media that are present to be consumed by modern society and one of them is Instagram useful benefits for the delivery of new information including one that is also used dalah things do business. The emergence of the phenomenon of online shopping in social media Instagram for the vigorous business conduct marketing using supporting figures or celebrities endorser as a supporter to market their products. Seeing this phenomenon, it is necessary to do a research that. Â Hamidah Rachmayanti is a celebrity endorser used by Online Shop Mayoutfit has several purposes in this research is to determine the effect of Visibility, Credibility, Attractiveness and Celebrity Endorser Effectiveness to the Decision Purchase Online Shop Mayoutfit products. This research uses quantitative method with questionnaire distribution and using multiple linear regression. Â This study concludes that the influence of Celebrity Endorser on @hamidahrachmayanti account of 52.1% can be explained by variables consisting of Visibility, Credibility, Attractiveness, and Power. Â
Vacuum-packed ripened sausages: evolution of volatile compounds during storage.

BACKGROUND Various studies have shown the ability of volatile compounds to influence the quality of charcuterie products because of their effect on sensorial properties. To the best of our knowledge, there are no data in the scientific literature concerning the evolution of volatile compounds of vacuum-packed ripened sausages over time. The aim of this work was to evaluate the evolution of volatile compounds in vacuum-packed ripened sausages over time, considering that this kind of packaging is the most commonly used to prolong the shelf-life of these products. RESULTS Sixty-nine volatile compounds were identified. Those derived from spices represented the prevailing compounds at the beginning of storage and significantly decreased (P<0.001) during 5 months of storage, as a result of the well-known antioxidant activity. Conversely, compounds derived from the autoxidation of lipids, which are among those chiefly responsible of sensorial properties of meat products, significantly increased (P<0.001). CONCLUSION The research demonstrated that vacuum packaging influenced the evolution of volatile compounds during storage of ripened sausages. In particular, the increase of volatile compounds derived from autoxidation of the lipid fraction indicated that oxidative processes involved the fatty fraction of ripened sausages also in the scarcity of oxygen.