Miracle-dz/UniFAR-FTUs huggingface dataset:
Case Report: Analytical Electron Microscopy of Lung Granulomas Associated with Exposure to Coating Materials Carried by Glass Wool Fibers

Context Man-made vitreous fibers (MMVFs) are noncrystalline inorganic fibrous material used for thermal and acoustical insulation (e.g., rock wool, glass wool, glass microfibers, and refractory ceramic fibers). Neither epidemiologic studies of human exposure nor animal studies have shown a noticeable hazardous effect of glass wools on health. However, MMVFs have been anecdotally associated with granulomatous lung disease in several case reports. Case presentation Here, we describe the case of a patient with multiple bilateral nodular opacities who was exposed to glass wool fibers and coating materials for 7 years. Bronchoalveolar lavage fluid revealed an increased total cell count (predominantly macrophages) with numerous cytoplasmic particles. Lung biopsy showed peribronchiolar infiltration of lymphoid cells and many foreign-body–type granulomas. Alveolar macrophages had numerous round and elongated platelike particles inside the cytoplasm. X-ray microanalysis of these particles detected mainly oxygen/aluminum/silicon and oxygen/magnesium/silicon, compatible with kaolinite and talc, respectively. No elemental evidence for glass fibers was found in lung biopsy. Discussion The contribution of analytical electron microscopy applied in the lung biopsy was imperative to confirm the diagnosis of pneumoconiosis associated with a complex occupational exposure that included both MMVFs and coating materials. Relevance to clinical or professional practice This case study points out the possible participation of other components (coating materials), beyond MMVFs, in the etiology of pneumoconiosis.
Extending the study of gelotophobia: On gelotophiles and katagelasticists

Abstract In Ruch and Proyer (Humor: International Journal of Humor Research 21:47–67, 2008a), the fear of being laughed at (gelotophobia) was introduced as a new individual differences phenomenon. In this article, two new laughter-related concepts are presented: gelotophilia (the joy of being laughed at) and katagelasticism (the joy of laughing at others). The main aim of the present article was an empirical verification of these three concepts. Data analyses from a construction (N = 390) and a replication sample (N = 157) led to a three factor solution for the data comprising the three concepts. Intercorrelations among the three groups suggest that there is a negative correlation between gelotophiles and gelotophobes and a positive relation between gelotophiles and katagelasticists. The correlation coefficients, however, indicate that there is a relation but that the concepts are not interchangeable. A reliable and stable standard 45-item questionnaire (PhoPhiKat-45) and an economic short form of 30 items (PhoPhiKat-30) for the assessment of the three concepts are presented. Additionally, it was shown that, contrary to what had to be expected from early literature on gelotophobia, remembered experiences of having been laughed at by parents and peers in childhood and youth cannot be considered as major contributors to the development of gelotophobic symptoms as an adult (the same is true for gelotophilia and katagelasticism). However, gelotophobes tended to remember more events of having been ridiculed by their father. Suggestions for future research and conceptual developments are given.
A Unified Subdivision Scheme for Polygonal Modeling

Subdivision rules have traditionally been designed to generate smooth surfaces from polygonal meshes. In this paper we propose to employ subdivision rules as a polygonal modeling tool, specifically to add additional level of detail to meshes. However, existing subdivision schemes have several undesirable properties making them ill suited for polygonal modeling. In this paper we propose a general set of subdivision rules which provides users with more control over the subdivision process. Most existing subdivision schemes are special cases. In particular, we provide subdivision rules which blend approximating spline based schemes with interpolatory ones. Also, we generalize subdivision to allow any number of refinements to be performed in a single step.
Manhole cover detection using a geometrical filter on very high resolution aerial and satellite images

One of the direct consequences of urban growth is the multiplication of buried utility networks. It is difficult to obtain complete and accurate maps of these networks because they have often been produced by different parties at different times. This work aims at putting forward a methodology to detect manhole covers on high resolution images, in order to reconstruct an urban drainage network. A circular detection filter is applied to high resolution orthophotos and Pléiade images to pinpoint mahole covers. The primary results are encouraging as 42% of manhole covers are detected by this method. Further work is carried out to improve the method and extend it to rectangular grates, that are not detected by the circular filter.
Digital Business Engineering: Methodological Foundations and First Experiences from the Field

Digitization is affecting almost all areas of business and society. It brings about opportunities for enterprises to design a digital business model. While a significant amount of research exist examining the conceptual foundation of business models in general, no comprehensive approach is available that helps enterprises in designing a digital business model. This paper addresses this gap and proposes Digital Business Engineering as a method for digital business model design. The activities are structured into six phases, namely End-to-End Customer Design, Business Ecosystem Design, Digital Product/Service Design, Digital Capability Design, Data Mapping, and Digital Technology Architecture Design. The method development follows principles of design-oriented research. Five case studies are used to analyse method requirements and evaluate it within is natural context.
A Synchronous Bisimulation Based Approach for Information Flow Analysis

A process algebra is defined where parallel composition is structured around synchronous communication. Its essential difference with CCS is the hypothesis that internal actions must be observable for the clock; consequently, in our formalism (strong) bisimulation will be the basis for information flow analysis, instead of equivalences based on trace or weak bisimulation. Bisimulation reduces in our formalism to equality modulo an ACUID equational theory extended with prefixes. We show that information flow analysis based on our formalism is finer than analyzes based on trace or weak bisimulation.
Facial Emotion Recognition Using PHOG and a Hierarchical Expression Model

In this paper, we propose a fast approach to detecting human facial emotions, using a hierarchical multiple stage scheme and only the PHOG feature descriptors basing on frontal images of human faces. In this model, the facial expression is the composition of a set of expressive facial regions which can be evaluated with the trained emotional templates. Within this framework, the proposed algorithm is able to achieve acceptable detection accuracy for Cohn-Kanade dataset, with less time and space complexities compared with the approaches in other research literature, making it applicable to low cost hardware such as mobile device. In addition, the experiments illustrated that the approach presented in this paper has good robustness and extendibility.
The role of neutrophil membrane glycoprotein GP-150 in neutrophil adherence to endothelium in vitro.

We have previously described two patients with a congenital defect in neutrophil function characterized by an inability to form pus. The patients' neutrophils lack a membrane glycoprotein of mol wt 150,000 daltons (GP-150) on analysis by SDS-PAGE. This glycoprotein is part of a membrane antigen complex recognized by the murine monoclonal antibody (MoAb) 60.3. Addition of MoAb 60.3 to normal neutrophils produces defects in chemotaxis and phagocytosis in vitro similar to those observed in the patients. Since neutrophil adherence to vascular endothelium is prerequisite to neutrophil emigration in vivo, we examined the interaction of the patients' neutrophils and normal neutrophils treated with MoAb 60.3 with cultured endothelium. Adherence was determined as the percentage of 51Cr-labeled purified peripheral blood neutrophils which remained adherent to plastic wells or endothelial monolayers after a 45-minute incubation at 37 degrees C. The percentage of neutrophils from patient 1 remaining adherent to uncoated, fibronectin-coated, or laminin-coated plastic was similar to that observed in normal neutrophils (55% to 84% adherence with normal neutrophils v 73% to 78% adherence with the patient's neutrophils and 63% to 82% adherence with MoAb 60.3-treated normal neutrophils). The adherence of the neutrophils from patient 1 and MoAb 60.3-treated normal neutrophils to human or bovine endothelium in serum-free medium was also not significantly different from that observed in normal neutrophils (less than 10% adherence with normal, MoAb 60.3-treated, and patient neutrophils). In medium containing 10% autologous or heterologous human plasma, however, the adherence of neutrophils from patient 1 or MoAb 60.3-treated normal neutrophils to endothelial monolayers was significantly reduced (35% +/- 7% of normal neutrophils in seven experiments). Although phorbol myristate acetate (PMA) (10 ng/mL) and calcium ionophore A23187 (10(-5) mol/L) markedly increased the adherence of normal neutrophils to endothelial monolayers in serum-free medium (40% to 85% adherence), neither agent increased the adherence of the neutrophils from patient 1 or normal neutrophils treated with MoAb 60.3 (less than 5% adherence). The adherence of PMA-activated neutrophils from patient 2 to endothelial monolayers was also markedly decreased when compared with that of normal neutrophils. Postsecretory cell-free supernatants from PMA-activated normal neutrophils failed to augment adherence of neutrophils from patient 1 (less than 5% adherence). (ABSTRACT TRUNCATED AT 400 WORDS)
Essay Review: Popper's Mystification of Objective Knowledge

I will first make some preliminary points about the word ’objective’. This will give substance to issues which are in danger of becoming too rarefied. Second, I will outline Popper’s account of objectivity. Third, I will argue that despite the value of what he says, his approach is seriously misleading. I will propose a formula for systematically transforming Popper’s theses and exposing what is important in them. This ’transformative method’ points the way towards an entirely different conception of what makes knowledge objective.
Saikosaponin-d Increases the Radiosensitivity of Hepatocellular Carcinoma Cell line SMMC-7721 by Adjusting the G 0 / G 1 and G 2 / M Checkpoints of Cell Cycle

Background: Saikosaponin-d (SSd) is a monomer terpenoid, purified from Chinese herbal drug Radix bupleuri, with multiple effects including anticancer. But the effect of SSd on the tumor exposed to radiation is largely unknown. To investigate he radiosensitive effect of SSd and its possible mechanism, we combined SS d with radiation therapy to treat hepatocarcinoma cell SMMC-7721 under oxia and hypoxia. Methods: The cell growth, cell apoptosis and cell cycle distribution were examined after treatment with SSd or radiation alone and their combinations in oxia and hypoxia. The protein and mRNA levels of p53, Bcl2 and BAX were measured by West ern blot and RT-PCR respectively. Results: In either oxia or hypoxia, SSd and radiation alone exposure resulted i n a cell growth inhibition and increased apoptosis rate at the concentration use d. And when treated with the combination of SSd and radiation, these effects were enhanced. More over, SSd not only potentiated the effects of radiation to induce Go/G1 arre st in SMMC-7721 cells, but also reduced the G2/M-phase population in hypoxia. However, in o xia, SSd only potentiated the effects of radiation to induce Go/G1 arrest ,bu not in G2/M-phase. In addition, these effects resulting from SSd or radiation and their combinations were companied with up-regulated expression of p53 and BAX, a down-regulation of Bcl2 in either oxia or hypoxia. Conclusion: It is demonstrated unambiguously that SSd potentiated the effect of ra diation in this cell line and would be a promising radiosensitizer. Radiosensi tizi g effect of SSd may contribute to its function to affect Go/G1 and G2/M checkpoints of cell cycle
A static characteristic analysis of proposed bi-directional dual active bridge DC-DC converter

Recently, the power supply network with energy storage devices such as battery has been focused. This network topology uses bi-directional isolated DC-DC converter of low or medium capacity is required for the diversification of power supply network. The dual active bridge (DAB) DC-DC converter is one of the effective bi-directional isolated DC-DC converters. However, the circuit has some instinct problems such as degradation of power efficiency and the occurrence of the surge in light-load operation. In this paper, we have been done a static characteristic analysis and highly power-efficient technique for DAB DC-DC Converter at light load. Also the analysis results and the proposed technique are verified with some experimental results.
Workplace bullying and interpersonal conflicts: the moderation effect of supervisor’s power / Acoso laboral y conflictos interpersonales: el papel moderador de las bases de poder del supervisor

Abstract Workplace bullying is considered the final stage of a prolonged conflict where there is a power imbalance between the affected parties and where emotional and relational problems exist. Thus, this study aims to explore the role of employee perceptions about the supervisor’s power bases on the relationship of conflict (i.e., task and relationship conflicts) and bullying at work. A cross-sectional survey study was conducted (N = 211). Results support a moderated-mediation model in which relationship conflict mediates the association between task conflict and workplace bullying, suggesting a conflict escalation process in bullying situations. In addition, establishing personal power bases seems to reduce the intensity of the link between task conflict and relationship conflict and, in turn, workplace bullying, whereas establishing positional power bases was not related to this association. Practical implications for bullying prevention are discussed.
The role of working memory components and visuospatial abilities in route learning within a virtual environment

An experiment was run to complete our understanding of the involvement of working memory (WM) components in the construction of a spatial model from visual input, considering some of the visuospatial abilities known to modulate performance. In addition, to allow for consideration of the flexibility of the spatial representation, routes in a virtual environment were presented with a route perspective, and tests were presented with route and survey perspectives. The results indicate that the verbal and spatial WM are only involved in the memorisation of certain types of information, and that their involvement depends on the change of perspective necessitated by the task. Thus, even when the learning material and the tests used to assess performance are only visual, a verbal recoding of some information is necessary. Moreover, individual differences modulate the involvement of WM; an individual with higher visuospatial capacities uses more spatial WM than an individual with lower spatial capacities.
Social Cues Modulate Cognitive Status of Discourse Referents

We use visual world eye-tracking to test if a speaker’s eye gaze to a potential antecedent modulates the listener’s interpretation of an ambiguous pronoun. Participants listened to stories that included an ambiguous pronoun, such as “The dolphin kisses the goldfish. He. ” During the prepronominal context, an onscreen narrator gazed at one of the two characters. As expected, participants looked more at the subject character overall. However, this was modulated by the narrator’s eye gaze and the amount of time the participant spent looking at the gaze cue. For trials in which participants attended to the narrator’s eye gaze for > 500ms, participants were significantly more likely to interpret the pronoun as referring to the object if the narrator had previously looked at the object. Results suggest that eye gaze – a social cue – can temper even strong linguistic/cognitive biases in pronoun resolution, such as the subject/first-mention bias.
Loop detection and automated route aggregation in distance vector routing

In this paper, a distance vector routing algorithm for IP computer networks is presented which is able to aggregate routes automatically and detect and prevent routing loops even on the aggregated routes. Route aggregation is the method of summarizing two or more routes to the corresponding destination IP subnetwork addresses into one common IP prefix address. Thus, it enables non-hierarchical network scalability by keeping the volume of routing and forwarding information within a reasonable size. Nevertheless, under certain circumstances route aggregation can cause network anomalies, e.g., routing and forwarding loops, which can seriously impact the performance and failure safety of the whole computer network. We describe an approach based on well-known Routing Information Protocol (RIPv2) that allows for the automation of route aggregation without manual intervention and still ensures loop-free forwarding paths and, therefore, short convergence times.
Phylogenetic Analysis Indicates Evolutionary Diversity and Environmental Segregation of Marine Podovirus DNA Polymerase Gene Sequences

ABSTRACT The distribution of viral genotypes in the ocean and their evolutionary relatedness remain poorly constrained. This paper presents data on the genetic diversity and evolutionary relationships of 1.2-kb DNA polymerase (pol) gene fragments from podoviruses. A newly designed set of PCR primers was used to amplify DNA directly from coastal sediment and water samples collected from inlets adjacent to the Strait of Georgia, British Columbia, Canada, and from the northeastern Gulf of Mexico. Restriction fragment length polymorphism analysis of 160 cloned PCR products revealed 29 distinct operational taxonomic units (OTUs), with OTUs within a site typically being more similar than those among sites. Phylogenetic analysis of the DNA pol gene fragments demonstrated high similarity between some environmental sequences and sequences from the marine podoviruses roseophage SIO1 and cyanophage P60, while others were not closely related to sequences from cultured phages. Interrogation of the CAMERA database for sequences from metagenomics data demonstrated that the amplified sequences were representative of the diversity of podovirus pol sequences found in marine samples. Our results indicate high genetic diversity within marine podovirus communities within a small geographic region and demonstrate that the diversity of environmental polymerase gene sequences for podoviruses is far more extensive than previously recognized.
Organisational and procedural justice: a review of the literature and its implications for policing

Organisational justice and procedural justice are complementary concepts that relate to the way individuals make judgments about fairness and outcomes when considering their interactions with others. Organisational justice and procedural justice comprise largely the same concepts, although their foci are different. Inwardly facing organisational justice is particularly concerned with the implications of justice judgments on staff attitudes, staff retention, workplace relations, productivity and performance. Outwardly facing procedural justice is—in the context of this paper—concerned with the interactions between police organisations and the public. This paper reports on the findings of a systematic review of the literature examining organisational and procedural justice in policing. We searched three comprehensive databases for literature on these themes. Fifty-seven empirical items were returned; five relating to organisational justice and police organisations, and 52 exploring procedural justice and police–public interactions. We explore this literature, and consider the implications for policing. We do so to set the scene for the other papers in this special edition. We conclude by noting that the extant literature has much to help police organisations better manage their internal and external relations, but that further effort should be made to turn empirically sound and theoretically interesting research into easily digestible and practically applicable models for police practitioners at all levels of the organisation.
Playback Latency Reduction for Internet Live Video Services in CDN-P2P Hybrid Architecture

Since Internet live video services provide media streaming over unmanaged networks, service cost and QoS (Quality-of-Service) are important factors for commercial deployment. For this open Internet content delivery, the CDN-P2P (Content Delivery Network-Peer-to-Peer) hybrid architecture can be an appropriate solution in terms of scalability and cost. In this live streaming system, lots of P2P (Peer-to-Peer) keeps the random unstructured graph for data delivery resilience even with node join and leave dynamics. However, since a node pulls required data from nearby peers in the unstructured overlay due to delivery graph elasticity, pull-based unstructured P2P live streaming services experience significant playback latency. In this paper, we propose a playback latency reduction method by limiting the radius of unstructured P2P in CDN-P2P hybrid architecture. Especially, we formulate this architecture as a BDMRST (Bounded-degree Minimum-radius Spanning Tree) problem and propose a distributed solution with slight modification of the gossip-based membership protocol. We also evaluate our proposed method with simulations.
Five design challenges for human computation

Human computation systems, which draw upon human competencies in order to solve hard computational problems, represent a growing interest within HCI. Despite the numerous technical demonstrations of human computation systems, however, there are few design guidelines or frameworks for researchers or practitioners to draw upon when constructing such a system. Based upon findings from our own human computation system, and drawing upon those published within HCI, and from other scientific and engineering literatures, as well as systems deployed commercially, we offer a framework of five challenging issues of relevance to designers of systems with human computation elements: designing the motivation of participants in the human computation system and sustaining their engagement; orienting participants, framing and orienting participants; using situatedness as a driver for content generation; considering the organisation of human and machine roles in human computation systems; and reconsidering the way in which computational analogies are applied to the design space of human computation.