Miracle-dz/UniFAR-FTUs huggingface dataset:
Serotonin Transporter Gene Polymorphic Element 5-HTTLPR Increases the Risk of Sporadic Parkinson’s Disease in Italy

Parkinson’s disease (PD) is a neurodegenerative disorder causing muscular rigidity, resting tremor and bradykinesia. We conducted an association study assessing how PD risk in Italy was influenced by the serotonin transporter gene (SLC6A4) polymorphic region 5-HTTLPR, consisting of an insertion/deletion (long allele-L/short allele-S) of 43 bp in the SLC6A4 promoter region. The SLC6A4 promoter single nucleotide polymorphism rs25531(A→G) was evaluated too. We collected 837 independent subjects (393 PD, 444 controls). An association between the 5-HTTLPR polymorphism and risk of PD (S/S genotype OR [95% CI]: 1.7[1.2–2.5], p = 0.002) was found. The rs25531 and the haplotype 5-HTTLPR/rs25531 did not associate with risk of PD. Our data indicate that the 5-HTTLPR polymorphic element within the SLC6A4 promoter may govern the genetic risk of PD in Italians.
Feed resources for ruminants

Treatment with urea, feeding of multi-nutritional blocks and high-offer level feeding are the interventions most likely to increase the potential nutritive value of fibrous crop residues. The exploitation of this potential will be determined by the level of supplementation with "bypass" nutrients, especially protein. The optimum level of supplementation will depend on the cost of the supplement and the added value of the increase in production. Multi-purpose crops which provide both feed and fuel will increasingly find a role as the demand increases for renewable sources of energy and increasing emphasis is put on the need for farming systems that have positive effects on the environment, especially the content of organic matter in soils.
Critical temperature and heating time for coagulation damage: Implications for interstitial laser coagulation (ilc) of tumors

Interstitial laser coagulation (ILC) is a method of local tissue destruction for solid tumors such as irresectable hepatic metastases from colorectal cancer. With the availability of new magnetic resonance (MR) techniques, which allow real time tissue temperature mapping, it is essential to know the critical temperature and exposure times leading to cell death.
On-chip transformer design and application to RF and mm-wave front-ends

• Monolithic transformers are synthesized from transmission lines; they are not "lumped elements" but do behave that way over a limited frequency range. Component parasitics must be captured to optimize RF circuit performance. • Stacked metal windings offer wider bandwidth and higher km than planar windings in some technologies. Metal thickness, intermetal dielectric thickness and metal height above substrate affects the performance of stacked vs. planar transformers. • Interconnect performance at RF is not well-understood, modeled or captured in conventional CAD tools. • Passive devices in Si-technology are not readily scalable, and further improvements in process technology and IC-CAD models of passive devices are needed for analog RF/MMIC applications.
DESIGN A PERCEPTION BASED SEMANTICS MODEL FOR KNOWLEDGE EXTRACTION

Innovation is developing its hands in practically every zone of criticalness. Fifth era PCs prompts instatement of artificial insight. PC can shape choice without anyone else's input. Word detecting issue is basic issue that is available in current. PC is by all accounts exceptionally astute in this. In the word detecting issue, the word we entered can have numerous different means yet PC ought to accept the right importance of word which we are attempting to pass on or which we truly mean of. PC can accept the specific significance of a word by our past hunts.
Sentiment Analysis in Social Networks through Topic modeling

In this paper, we analyze the sentiments derived from the conversations that occur in social networks. Our goal is to identify the sentiments of the users in the social network through their conversations. We conduct a study to determine whether users of social networks (twitter in particular) tend to gather together according to the likeness of their sentiments. In our proposed framework, (1) we use ANEW, a lexical dictionary to identify affective emotional feelings associated to a message according to the Russell’s model of affection; (2) we design a topic modeling mechanism called Sent_LDA, based on the Latent Dirichlet Allocation (LDA) generative model, which allows us to find the topic distribution in a general conversation and we associate topics with emotions; (3) we detect communities in the network according to the density and frequency of the messages among the users; and (4) we compare the sentiments of the communities by using the Russell’s model of affect versus polarity and we measure the extent to which topic distribution strengthen likeness in the sentiments of the users of a community. This works contributes with a topic modeling methodology to analyze the sentiments in conversations that take place in social networks.
Learning Disabilities in the United States

This overview offers a perspective on the distinguishing characteristics, past and present, of the LD field in the United States. The discussion focuses on the complex relationships that exist among the social and political forces that have molded the field, advocacy, and research and teaching practices. It emphasizes the compelling need to establish clinical and scientific validation of LD, to preserve the hard-won achievements of advocacy.
Feedipedia Animal feed resourcesinformation system

Neem, neem tree, Indian lilac, margosa, nimtree [English]; margousier, margosier, neem [French]; nim, margosa, lila india [Spanish]; amargosa [Portuguese]; Niembaum [German]; mimba [Indonesian]; mwarobaini [Kiswahili]; sầu đâu [Vietnamese]; عئاش مين [Arabic]; [Bengali]; [Burmese]; [Gujarati]; תידוה תכרדזא [Hebrew]; [Hindi]; インドセンダン [Japanese]; [Kannada]; [Marathi]; [Mayalayam]; [Nepalese]; [Pendjabi]; من [Western punjabi]; شيرچ [Persian]; Ниим [Russian]; [Tamil]; สะเดา [Thai]
Parameter Estimation for Condition Monitoring of PMSM Stator Winding and Rotor Permanent Magnets

Winding resistance and rotor flux linkage are important to controller design and condition monitoring of a surface-mounted permanent-magnet synchronous machine (PMSM) system. In this paper, an online method for simultaneously estimating the winding resistance and rotor flux linkage of a PMSM is proposed, which is suitable for application under constant load torque. It is based on a proposed full-rank reference/variable model. Under constant load torque, a short pulse of id ≠ 0 is transiently injected into the d-axis current, and two sets of machine rotor speeds, currents, and voltages corresponding to id = 0 and id ≠ 0 are then measured for estimation. Since the torque is kept almost constant during the transient injection, owing to the moment of system inertia and negligible reluctance torque, the variation of rotor flux linkage due to injected id ≠ 0 can be taken into account by using the equation of constant torque without measuring the load torque and is then associated with the two sets of machine equations for simultaneously estimating the winding resistance and rotor flux linkage. Furthermore, the proposed method does not need the values of the dq-axis inductances, while the influence from the nonideal voltage measurement, which will cause an ill-conditioned problem in the estimation, has been taken into account and solved by error analysis. This method is finally verified on two prototype PMSMs and shows good performance.
Accessibility of the promoter sequence in the J-chain gene is regulated by chromatin changes during B-cell differentiation

The gene for the immunoglobulin M (IgM)-polymerizing protein, the J chain, is activated when the mature B cell is triggered to secrete pentamer IgM. Activation of the gene was found to be associated with chromatin changes in a 240-base-pair region at the 5' end of the gene. Analyses of lymphoid lines showed that the 5' region was resistant to nuclease digestion at the immature B-cell stage; it became slightly more accessible in mature B cells and cells at an early stage in the IgM response and then displayed an open, hypersensitive structure in IgM-secreting cells. In addition, analyses of normal, mitogen-stimulated lymphocytes showed that the open hypersensitive structure was coinducible with J-chain gene expression. These results suggest that the 5' chromatin changes precede transcription, making control sequences within the site accessible to regulatory factors.
First step towards a cost-effective lot platform for customers power consumption awareness

The paper deals with the definition, implementation and performance assessment of an Internet of things (IoT) platform for measuring and monitoring power consumption in smart home or smart industry applications. Thanks to the adoption of suitable cost-effective hardware components and a proper software architecture implemented on Raspberry PI, the IoT platform can assure real-time power monitoring on electrical loads connected to domestic and industrial power plugs. Particular attention has been paid to the selection of the application layer protocol mandated to exchange data between the power measuring nodes and the Raspberry PI in order to assure reliable communication with a reduced computational and connection overhead. The availability of the measurement results on a web page that does not require any specific software but a web browser highlights the efficacy of the adopted platform to assure aware in power consumption for domestic and industrial customers.
Occurrence and Determinants of Postpartum Maternal Morbidities and Disabilities among Women in Matlab, Bangladesh

The burden of maternal ill-health includes not only the levels of maternal mortality and complications during pregnancy and around the time of delivery but also extends to the standard postpartum period of 42 days with consequences of obstetric complications and poor management at delivery. There is a dearth of reliable data on these postpartum maternal morbidities and disabilities in developing countries, and more research is warranted to investigate these and further strengthen the existing safe motherhood programmes to respond to these conditions. This study aims at identifying the consequences of pregnancy and delivery in the postpartum period, their association with acute obstetric complications, the sociodemographic characteristics of women, mode and place of delivery, nutritional status of the mother, and outcomes of birth. From among women who delivered between 2007 and 2008 in the icddr,b service area in Matlab, we prospectively recruited all women identified with complicated births (n=295); a perinatal mortality (n=182); and caesarean-section delivery without any maternal indication (n=147). A random sample of 538 women with uncomplicated births, who delivered at home or in a facility, was taken as the control. All subjects were clinically examined at 6-9 weeks for postpartum morbidities and disabilities. Postpartum women who had suffered obstetric complications during birth and delivered in a hospital were more likely to suffer from hypertension [adjusted odds ratio (AOR)=3.44; 95% confidence interval (CI)=1.14-10.36], haemorrhoids (AOR=1.73; 95% CI=1.11-3.09), and moderate to severe anaemia (AOR=7.11; 95% CI=2.03-4.88) than women with uncomplicated normal deliveries. Yet, women who had complicated births were less likely to have perineal tears (AOR=0.05; 95% CI=0.02-0.14) and genital prolapse (AOR=0.22; 95% CI=0.06-0.76) than those with uncomplicated normal deliveries. Genital infections were more common amongst women experiencing a perinatal death than those with uncomplicated normal births (AOR=1.92; 95% CI=1.18-3.14). Perineal tears were significantly higher (AOR=3.53; 95% CI=2.32-5.37) among those who had delivery at home than those giving birth in a hospital. Any woman may suffer a postpartum morbidity or disability. The increased likelihood of having hypertension, haemorrhoids, or anaemia among women with obstetric complications at birth needs specific intervention. A higher quality of maternal healthcare services generally might alleviate the suffering from perineal tears and prolapse amongst those with a normal uncomplicated delivery.
Negation of protein-protein interactions: analysis and extraction

MOTIVATION Negative information about protein-protein interactions--from uncertainty about the occurrence of an interaction to knowledge that it did not occur--is often of great use to biologists and could lead to important discoveries. Yet, to our knowledge, no proposals focusing on extracting such information have been proposed in the text mining literature. RESULTS In this work, we present an analysis of the types of negative information that is reported, and a heuristic-based system using a full dependency parser to extract such information. We performed a preliminary evaluation study that shows encouraging results of our system. Finally, we have obtained an initial corpus of negative protein-protein interactions as basis for the construction of larger ones. AVAILABILITY The corpus is available by request from the authors.
The Forgotten Driving Forces in Right Heart Failure: New Concept and Device

Background: Right heart failure is a frequent hemodynamic disturbance in pediatric cardiac patients. Besides inotropic and chronotropic drugs, fluid administration and inhaled nitric oxide, right ventricular mechanical assistance remains difficult to perform. A circulatory assist device adapted for the right heart biophysics and physiology might be more efficient. Materials and Methods: We are developing a prototype of a non-invasive cardiac assist device (CAD) for neonates and pediatrics. It is based on a pulsatile suit device covering and affecting all territories of the right heart circuit. It will be tested in a neonatal animal model of right ventricular (RV) failure. Experimental models will be matched and compared with control and sham groups. Expected results would be immediate hemodynamic improvement due to synchronized diastolic reduction of stagnant venous capacitance, increasing preload and contractility. On long term, increased shear stress with changing intrathoracic pressure in a phasic way would improve and remodel the pulmonary circulation. Future studies will be focused on: hemodynamic, biochemistry, endothelium function test, and angiogenesis. Comments: A non-invasive CAD guarantees better hemodynamics and endothelial function preservation with low morbidity and mortality. This is a physiological approach, cost-effective method, and particularly interesting in neonates and pediatrics with RV failure.
Citicafe: conversation-based intelligent platform for citizen engagement

Community civic engagement is a new and emerging trend in urban cities driven by the mission of developing responsible citizenship. The recognition of civic potential in every citizen goes a long way in creating sustainable societies. Technology is playing a vital role in helping this mission and over the last couple of years, there have been a plethora of social media avenues to report civic issues. Sites like Twitter, Facebook, and other online portals help citizens to report issues and register complaints. These complaints are analyzed by the public services to help understand and in-turn address these issues. However, once the complaint is registered, often no formal or informal feedback is given back from these sites to the citizens. This de-motivates citizens and may deter them from registering further complaints. In addition, these sites offer no holistic information about a neighborhood to the citizens. It is useful for people to know whether there are similar complaints posted by other people in the same area, the profile of all complaints and a know-how of how and when these complaints will be addressed. In this paper, we create a conversation-based platform CitiCafe for enhancing citizen engagement front-ended by a virtual agent with a Twitter interface. This platform back-end stores and processes information pertaining to civic complaints in a city. A Twitter based conversation service allows citizens to have a direct correspondence with CitiCafe via "tweets" and direct messages. The platform also helps citizens to (a) report problems and (b) gather information related to civic issues in different neighborhoods. This can also help, in the long run, to develop civic conversations among citizens and also between citizens and public services.
In vitro investigation of BK-218, a new oral and parenteral cephalosporin

The antibacterial activity of BK-218 was similar to that of cefamandole when it was tested against several laboratory strains. The inhibiting effect of BK-218 was greater than that of cephalexin and cefoxitin on penicillin-binding proteins of Escherichia coli HB101. This result was in close correlation with the relative inhibition of radiolabeled glucosamine incorporation (greatest with BK-218) and with the lytic effect (most intensive with BK-218). BK-218 proved to be a good inhibitor for all five of the beta-lactamases that were investigated, although two enzymes (Enterobacter cloacae P99 and Pseudomonas aeruginosa Cilote) hydrolyzed it to some extent.
Alkaline phosphatase-positive cells isolated from human hearts have mesenchymal stem cell characteristics

Tissue-specific resident cells have been identified as a promising population of progenitor cells for cell-based therapies. We describe here the isolation from adult human hearts of tissue nonspecific alkaline phosphatase-positive cells (ALPL+ cells) with mesenchymal stem cell (MSC) characteristics. Samples from 24 adult cadaveric donors were obtained from a valve bank. Mean total ischemia time was 21.5 ± 9.1 hours. The success rate for the isolation of human heart-derived cells by the explant culture technique was 70% for the right auricle (14 of 20 trials) and 33% for the right ventricle (7 of 21 trials). The total auricle-derived cell population (TAD) was used for the purification of ALPL+ cells. TAD and ALPL+ cells expressed markers for MSC and pericytes. TAD cells and ALPL+ cells differentiated into adipocytes, osteoblasts and chondroblasts, and ALPL+ cells expressed markers of these three lineages more strongly than TAD cells, as shown by RT-PCR. This population therefore has a greater potential for differentiation into mesechymal lineages than TAD cells. Both cell populations express some markers of cardiac progenitors, such as GATA4, CD117 and VEGF. ALPL+ cells expressed troponin T and ABCG2, which are also markers of the cardiac lineage. Heart samples from tissue banks could be considered as sources of MSC with putative commitment towards cardiac lineages, even after prolonged ischemia times.
Prevalence of very mild to severe dementia in Denmark

Objectives ‐ The prevalence of dementia has been estimated in several countries and a meta‐analysis has shown moderate and severe dementia in people aged 65 years and older to be between 4% and 6%. The Odense study is aiming to estimate the prevalence and incidence of dementia and to identify risk factors. Material and methods ‐ A total of 3346 persons, equivalent to 64.5% of a random sample of 5237 persons aged 65–84 years living in the municipality of Odense, Denmark, underwent a two phase diagnostic procedure including a screening with CAMCOG, the cognitive section of The Cambridge Examination for Mental Disorders of the Elderly, seven neuropsychological tests, medical examination, and CT scan. The severity of dementia was assessed by the CDR (Clinical Dementia Rating). Results ‐ The prevalence rate was 7.1%, including the very mildly demented, defined as persons rated questionably demented according to the CDR scale. The prevalence rate of very mild dementia was 2.8%. The proportion of cases with very mild dementia decreased with increasing age while the prevalence rate increased. Conclusion ‐ Inclusion of very mild cases of dementia resulted in a higher prevalence rate than generally reported, and the prevalence rate increased exponentially with age which was mainly due to Alzheimer's disease.
Caracterisation des detecteurs du spectrometre infrarouge omega embarque sur la mission spatiale mars '96. Implications sur l'etude de la planete mars

Le spectrometre infrarouge omega embarque sur la mission spatiale mars '96 va permettre de caracteriser pour la premiere fois les regions polaires et les regions equatoriales de la planete mars a haute resolution spatiale et a moyenne resolution spectrale dans le domaine de longueur d'ondes de 0,3 m a 5 m. Cet instrument utilise un type de detecteurs qui n'a jamais ete utilise dans une experience planetaire: des barrettes d'antimoniure d'indium refroidies a moins de 80 k, couplees a un dispositif a transfert de charges. L'objectif principal des travaux presentes a ete de definir les caracteristiques de fonctionnement de ce type de detecteur (courants d'obscurite et bruit total). L'un des aspects les plus importants etait l'evolution du bruit total en fonction de la temperature de fonctionnement, du temps d'integration et du nombre de charges transferees. Une augmentation significative a ete observee a basse temperature, qui a pu etre interpretee sur la base d'un bruit de piegeage des charges dans le dispositif a transfert de charges. Le fonctionnement de l'ensemble de detection a ainsi pu etre optimise. En conclusion, les consequences de ces resultats sur les modes d'utilisation et l'exploitation scientifique de l'experience omega sont presentees
Health Benefits of Cobblestone-Mat Walking: Preliminary Findings

This study examined the effect of cobblestone-mat walking on health-related outcomes in older adults. Participants (mean age 72.6, N=40) were randomized into either an 8-week cobblestone-mat walking activity (n = 22) or a control group (n = 18). Cobblestone-mat walking entailed three 45-min sessions per week. Primary outcomes included SF-12 (mental, physical), instrumental activities of daily living (IADLs), psychophysical well-being, daytime sleepiness, and pain. Secondary outcomes included resting blood pressure and perceived control of falls. The walkers experienced significantly improved SF-12 scores, IADLs, and psychophysical well-being and significantly reduced daytime sleepiness and pain. They also reported significantly improved perceptions of control over falls. A significant between-groups difference in resting diastolic blood pressure was observed, with reductions in the walkers. A significant within-group reduction in systolic blood pressure was observed in the walkers only. The data indicate .