Miracle-dz/UniFAR-FTUs huggingface dataset:
Job stress dimension and work-related musculoskeletal disorders among southeast Nigerian physiotherapists

Background. Although publications describe physical demands of the job in the physiotherapy profession, there is a dearth of literature on job stress dimensions (JSDs), and their relationship to work-related musculoskeletal disorders (WMSDs). Objective. To investigate JSDs and their relationship to WMSDs among physiotherapists currently practicing in southeast Nigeria. Method. A cross-sectional study using items related to the Job Content Questionnaire and the Nordic musculoskeletal questionnaire. Data were summarized with descriptive statistics, and the relationship between WMSDs and JSDs was analyzed with the Mann–Whitney U test. Results. A total of 126 physiotherapists responded. There were high levels of stress in most of the job dimensions investigated: 82.1% and 22.8% of the physiotherapists had WMSDs in at least one body region in the last 12 months and the last 7 days respectively. The lower back was the most commonly affected in both periods. No specific domain was related to development of WMSDs. Conclusion. Over 80% of physiotherapists in southeast Nigeria have WMSDs. However, despite high levels of physical demands on the job, physiotherapists have job control and good social support. Intervention programs aimed at reducing WMSDs in physiotherapists should focus on risk factors that target the physical demands of the job.
Re-Ranking Web Images

: Image Search engines mostly use keywords and they rely on text for searching images. The search based on only keywords fire by the users is not efficient and may results in imprecise output. The major bottleneck is likely mismatch between the image content and the given text. Image search reranking attempts to resolve this bottleneck by relying on both the text information and visual information during the image search process. This paper reviews the trends in image search reranking, discusses the problems found along the way, and identifies the ideas that should guide future activities in this research. According to the paper by Xiaogang Wang, Shi Qiu, Ke Liu, and Xiaoou Tang, images are re-ranked by comparing their semantic signatures and the query keyword [1]. The query-specific semantic signatures, in the reviewed paper, improve both the accuracy and efficiency of the re-ranking process. In literature, experimental result shows that by using the re-ranking technique they can improve the web image search. In this reviewed paper, different types of web image search re-ranking techniques are explained.
A novel saliency detection method via manifold ranking and compactness prior

For improving the performance of saliency detection, several algorithms used graph construction have achieved excellent results. This paper proposes a novel bottom-up approach of saliency detection, which takes the advantages of both prior background and compactness. At first, we optimize the image boundary selections, by removing erroneous sections with a fixed threshold, to achieve more accurate saliency estimation results. The saliency map obtained by ranking with background queries can be optimized with compactness prior. The objects of salient are connected regions which are group together, with a compact form which are spatial distributed. Compared to the 8 state-of-the-art saliency detection approaches, our experimental results which test on the three public datasets show that the proposed algorithm improves accuracy and robustness significantly. This algorithm can find its potential applications in many different areas, but it is best suit for medical science and technologies because of high accuracy requirements. It can be used in the medical imaging processing to accurately differentiate tumor from bones, muscles and fats.
Server Initiated Model Using Location Based Service

In current scenario everyone using the internet for effectuating their work uncomplicated. Location Based Service is one of the constituents of this internet world. With the comfort of location based service people chase location uncomplicatedly. But extant Location Based Service systems apply pull model or user initiated model. In the pull model, user chases their location then the user will access response but now I apply push model or server initiated model in which users will access clamant response. In the push, model server conveys to the user according to the extant location of a user. Many researchers applied many algorithms in LBS systems like RT tree algorithm but I will apply Binary search tree algorithm on the location-based service application which is convenient for the quick retort. In research work, I compare that Binary Search Tree gives us retort in less time more than other comparing technique.
Benefit-Cost Analysis of a Cleft Lip and Palate Surgical Subspecialty Hospital in India

1. Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts, United States of America 2. Program in Global Surgery and Social Change, Department of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, United States of America 3. Nicholas School of the Environment and Sanford School of Public Policy, Duke University, Durham, North Carolina, United States of America 4. Department of Plastic and Oral Surgery, Boston Children's Hospital, Boston, Massachusetts, United States of America
STATUS QUO IN FLOW-THROUGH CYTOMETRY

Flow-through systems of single cell analysis and sorting have been under development for several years. Fluorescence and volume sensors are well developed but light scatter sensors can be expected to improve. Cell sorters are in use in several laboratories and commercial versions are under development. The most serious problems in flow-through cytometry are in cell preparation and the greatest potential for advancement lies in development of new, specific stains and markers.
2D TR-NOESY experiments interrogate and rank ligand-receptor interactions in living human cancer cells.

Recent advances in cancer therapy include the design ofmolecules that interfer with tumor angiogenesis and moietiesthat recognize specific receptors expressed onto the tumorendothelium and/or onto tumor cells, thus allowing theligand-directed targeted delivery of various drugs and par-ticles to tumors. In this context, integrin avb3 and themembrane-spanning surface protein aminopeptidase N(CD13) play a pivotal role in tumor growth and metastaticspread, as they are important membrane-bound receptorshighly expressed during angiogenesis.
Rodent Models of Focal Cerebral Ischemia

This unit presents models that are both used to study ischemic mechanisms and to test for neuroprotective agents or agents that enhance recovery from stroke. The Tamura model is one of the best characterized focal ischemia models in which the middle cerebral artery is occluded by electrocoagulation. Also described is the intraluminal monofilament model, the spontaneously hypertensive rat (SHR), and the newer endothelin‐1 model. The rationale behind the use of animal models, the various types of models and advantage and disadvantages of each model are presented.
Interactions between temperature and drought in global and regional crop yield variability during 1961-2014

Inter-annual crop yield variation is driven in large parts by climate variability, wherein the climate components of temperature and precipitation often play the biggest role. Nonlinear effects of temperature on yield as well as interactions among the climate variables have to be considered. Links between climate and crop yield variability have been previously studied, both globally and at regional scales, but typically with additive models with no interactions, or when interactions were included, with implications not fully explained. In this study yearly country level yields of maize, rice, soybeans, and wheat of the top producing countries were combined with growing season temperature and SPEI (standardized precipitation evapotranspiration index) to determine interaction and intensification effects of climate variability on crop yield variability during 1961–2014. For maize, soybeans, and wheat, heat and dryness significantly reduced yields globally, while global effects for rice were not significant. But because of interactions, heat was more damaging in dry than in normal conditions for maize and wheat, and temperature effects were not significant in wet conditions for maize, soybeans, and wheat. Country yield responses to climate variability naturally differed between the top producing countries, but an accurate description of interaction effects at the country scale required sub-national data (shown only for the USA). Climate intensification, that is consecutive dry or warm years, reduced yields additionally in some cases, however, this might be linked to spillover effects of multiple growing seasons. Consequently, the effect of temperature on yields might be underestimated in dry conditions: While there were no significant global effects of temperature for maize and soybeans yields for average SPEI, the combined effects of high temperatures and drought significantly decreased yields of maize, soybeans, and wheat by 11.6, 12.4, and 9.2%, respectively.
A buried polar interaction imparts structural uniqueness in a designed heterodimeric coiled coil.

Buried polar residues are a common feature of natural proteins. ACID-p1 and BASE-p1 are two designed peptides that form a parallel, heterodimeric coiled coil with a fixed tertiary structure [O'Shea, E. K. , Lumb, K. J., & Kim, P. S. (1993) Curr. Biol. 3, 658-667]. The interface between the ACID-p1 and BASE-p1 helices consists of hydrophobic Leu residues, with the exception of a single polar residue, Asn 14. In the crystal structure of the GCN4 leucine zipper coiled coil, an analogous Asn is hydrogen bonded to the corresponding Asn of the opposing helix, thereby forming a buried polar interaction in an otherwise hydrophobic interface between the helices [O'Shea, E. K. , Klemm, J. D. , Kim, P. S. , & Alber, T. (1991) Science 254, 539-544]. This buried polar interaction in the ACID-p1/BASE-p1 heterodimer was removed by substituting Asn 14 with Leu. The Asn 14-->Leu variants are significantly more stable than the p1 peptides and preferentially form a heterotetramer instead of a heterodimer. Strikingly, the heterotetramer does not fold into a unique structure; in particular, the helices lack a unique orientation. Thus, the Asn 14 residue imparts specificity for formation of a two-stranded, parallel coiled coil at the expense of stability. The results suggest that, whereas nonspecific hydrophobic interactions contribute to protein stability, the requirement to satisfy the hydrogen bonding potential of buried polar residues in the generally hydrophobic environment of the protein interior can impart specificity (structural uniqueness) to protein folding and design.
Adaptive Transit Routing in Stochastic Time-Dependent Networks

We define an adaptive routing problem in a stochastic time-dependent transit network in which transit arc travel times are discrete random variables with known probability distributions. We formulate it as a finite horizon Markov decision process. Routing strategies are conditioned on the arrival time of the traveler at intermediate nodes and real-time information on arrival times of buses at stops along their routes. The objective is to find a strategy that minimizes the expected travel time, subject to a constraint that guarantees that the destination is reached within a certain threshold. Although this framework proves to be advantageous over a priori routing, it inherits the curse of dimensionality, and state space reduction through preprocessing is achieved by solving variants of the time-dependent shortest path problem. Numerical results on a network representing a part of the Austin, Texas, transit system indicate a promising reduction in the state space size and improved tractability of the dynamic program.
Travel writing and gender

The essence of adventure lies in taking risks and exploring the unknown, so it is hardly surprising to find that early travel accounts tended for the most part to be written by men, who moved more freely in the public sphere. The great European sagas of knightly questing (such as The Norse Sagas and The Arthurian Cycle ) or seafaring exploration (such as The Odyssey and The Lusiads ) are also male narratives with women the objects of desire or destination points rather than active co-travellers, though the figure of the warrior-princess roaming the world in search of adventure was popular in Renaissance epics like Orlando furioso and Gerusalemme liberata . The adventure quest in the sixteenth and seventeenth centuries, when men journeyed in search of fortune and renown to the new worlds that were opening up beyond the frontiers of Europe, was explicitly gendered, since the idea of man as heroic risk-taking traveller underpinned not only the great travel narratives of the next centuries, but much of the travel writing of the twentieth century also. Alongside the myths of the heroic explorer, however, are other kinds of narrative, some of which have been produced by women. The travel text as ethnography or social commentary transcends gender boundaries and, increasingly in the twentieth century, male and female travellers have written self-reflexive texts that defy easy categorisation as autobiography, memoir, or travel account. There is also, in British travel writing, a tendency to self-deprecation and irony, a style of writing that has both Henry Fielding and Jane Austen as its antecedents, despite the fact that the latter did not move beyond the confines of southern England. Contemporary writers like Redmond O’Hanlon and Eric Newby subvert or satirise the image of the explorer-hero, turning themselves into anti-heroes in their narratives, a comic reversal of the dominant image of the male traveller who seeks to boldly go where no man has gone before.
Modulation of gene expression by antisense and antigene oligodeoxynucleotides and small interfering RNA

Antisense oligodeoxynucleotides, triplex-forming oligodeoxynucleotides and double-stranded small interfering RNAs have great potential for the treatment of many severe and debilitating diseases. Concerted efforts from both industry and academia have made significant progress in turning these nucleic acid drugs into therapeutics, and there is already one FDA-approved antisense drug in the clinic. Despite the success of one product and several other ongoing clinical trials, challenges still exist in their stability, cellular uptake, disposition, site-specific delivery and therapeutic efficacy. The principles, strategies and delivery consideration of these nucleic acids are reviewed. Furthermore, the ways to overcome the biological barriers are also discussed so that therapeutic concentrations at their target sites can be maintained for a desired period.
Designing discriminative spatial filter vectors in motor imagery brain–computer interface

The problem of a volume conduction effect in electroencephalography is considered one of the challenging issues in brain–computer interface (BCI) community. In this article, we propose a novel method of designing a class‐discriminative spatial filter assuming that a combination of spatial pattern vectors, irrespective of the eigenvalues of the common spatial pattern (CSP), can produce better performance in terms of classification accuracy. We select discriminative spatial filter vectors that determine features in a pairwise manner, that is, eigenvectors of the K largest eigenvalue and the K smallest eigenvalue. Although the pair of the eigenvectors of the K largest and the K smallest eigenvalues helps extract discriminative features, we believe that a different set of eigenvector pairs is more appropriate to extract class‐discriminative features. In our experimental results using the publicly available dataset of BCI Competition IV, we show that the proposed method outperformed the conventional CSP methods and a filter‐bank CSP. © 2013 Wiley Periodicals, Inc. Int J Imaging Syst Technol, 23, 147–151, 2013
Effect of Tai-chi exercise on lower limb muscle strength, bone mineral density and balance function of elderly women.

UNLABELLED To study the effect of Tai-chi exercise on lower limb muscle strength, bone mineral density and balance function of elderly female, 105 urban elderly women, who do insufficient exercise in daily life, are selected as the subject and randomly divided into an observation group (Tai Chi Group), a control group I (Dance Group) and a control group II (Walking Group). Each group is consists of 35 women. Among them, the women in the observation group do Tai-chi exercise once a day, while the women in the control group I dance once a day and in the control group II stick to brisk walking once a day. All women in the three groups do the above said exercises for 40 minutes and the exercise intensity is controlled to be medium. At the time of selection and after 4, 8 and 12 months upon their exercises, respectively detect and compare the lower limb skeletal muscle mass, lower limb muscle strength, bone mineral density and balance function of the subject. RESULTS At the time of selection, the general information of the subjects in the three groups show no significant difference (P > 0.05); however, after 4 months' exercise, most of the study indexes in the control group I and group II are improved significantly (P < 0.05), while most of the study indexes in the observation group show no significant difference (P > 0.05) in comparison with those at the time of selection and their general improvement effect is slightly lower than that in the control group; after 8 months, relevant study indexes of the subjects in the three groups are significantly improved (P < 0.05) in comparison with those at the time of selection, especially, the effect in the observation group is more obvious and is better than that of the control group II (P < 0.05). 12 months later, the effect of the observation group is improved significantly from day to day when comparing to theose in the control group I and group II (P < 0.05 or P < 0.01). CONCLUSION Compared with the senile dance and walking exercises, the short-term Tai-chi exercise effect is not obvious, however, once the exercise period is extended, that is, continuous exercise for 8 months or even above 12 months, the advantage of Tai Chi is more and more significant. The study suggests that as a fitness measure, Tai Chi is more suitable for long-term exercise and its short-term effect is not obvious.
ChARMin: The First Actuated Exoskeleton Robot for Pediatric Arm Rehabilitation

ChARMin is the first actuated exoskeleton robot for pediatric arm rehabilitation. The device was specifically designed to provide intensive rehabilitative training for children with affected arm motor function, e.g., due to cerebral palsy; therewith complementing conventional therapies. This paper gives a comprehensive overview of the ChARMin robot, which provides six actuated degrees of freedom, and is designed to cover the complete target group of children and adolescents aged 5-18 years. Moreover, the new audiovisual game-like interface is presented, which motivates active participation of the child. To support the child's arm movements with the exoskeleton, a patient-cooperative control strategy was implemented. The controller enables free arm movements, assistance-as-needed, and complete guidance of the arm. Five children aged 5-17 years with impaired arm motor function due to cerebral palsy, stroke, and traumatic brain injury tested the various training scenarios with different amounts of support, and robot settings depending on the therapeutic goals and the children's movement capabilities and preferences. These preliminary tests suggest that the ChARMin setup can be used as an advanced exercise tool for arm neurorehabilitation that optimally challenges children and adolescents with severely to moderately affected arm motor functions.
Association of Activated T Cells and Dendritic Cells in Atherosclerotic Lesions in Apo E-Deficient Mice

Background: Antigen-specific T cell activation plays an important role in the initiation and progression of atherosclerosis. T cell activation can occur only if antigen is presented to T cells by antigenpresenting cells expressing co-stimulatory signal molecules. Apo E-deficient mice are widely used for investigating the role of antigen-presenting dendritic cells in atherosclerosis. Although the accumulation of dendritic cells in developing atherosclerotic lesions in apo E-deficient mice has been shown, it is still unknown whether dendritic cells might activate T cells directly within atherosclerotic lesions. Aims: The present study was undertaken to examine this question. We investigated whether the marker T cell activation IL-2 receptor beta chain and the dendritic cell co-stimulatory molecules CD80 and CD86 were co-expressed in atherosclerotic lesion areas that contained co-localized T cells and dendritic cells. Methods: Aortic atherosclerotic plaques obtained from apo E knockout mice were studied using an immunohistochemical approach. Results: We found a co-localized expression of CD3, CD11c, CD80, CD86 and IL-2 receptor beta chain in all analyzed tissue specimens. This observation suggests that primary activation of T cells might occur directly within atherosclerotic lesions in apo E-deficient mice.
Occupational performance and strategies for managing daily life among the elderly with heart failure

Abstract Aim: The aim of this study was to describe experiences of limitations in occupational performance and strategies for managing daily activities among the elderly with chronic heart failure (CHF). Methods: Ten participants from primary healthcare with a confirmed diagnosis of CHF were interviewed. The interviews were analysed using qualitative content analysis. Results: The first theme, “Redefining an active life, aware of one’s impaired body”, was based on four sub-themes: realizing one’s limited activity ability; striving to preserve an active life; focusing on meaningful activities; and changing vs. not changing habits and roles. The second theme, “Planning activities and balancing the degree of effort”, was based on three sub-themes: limiting, organizing, and rationalizing activities; adjusting activities to today’s ability; and using technology and adapting the environment. Conclusions: Elderly people with CHF are struggling with an ongoing process of occupational adaptation due to periodical physical decline and fluctuating day-to-day ability. This highlights a need for information on strategies from a holistic perspective and client-centred occupational therapy interventions.
IDDM Is a Risk Factor for Adolescent Psychiatric Disorders

OBJECTIVE To determine whether the rate of psychiatric disorders increases in children and adolescents with IDDM. RESEARCH DESIGN AND METHODS The rate of psychiatric disorders was assessed by highly structured interviews in a group of 93 IDDM adolescents 17–19 yr of age and compared with a healthy (nondiabetic) age-, sex-, and socioeconomic status-matched control group. RESULTS The rate of psychiatric disorders was 33.3% in the diabetic group, more than threefold higher than in the control group (9.7%). With regard to the ratepsychiatric disorders, no sex-specific differences between the two groups were found. The diabetic adolescents suffered from significantly more introversive symptoms than their healthy counterparts, especially somatic symptoms, sleeping disturbances, compulsions, and depressive moods. In spite of the elevated rate of psychiatric disorders, the rates of life events and familial adversities did not increase in the diabetic group. CONCLUSIONS The results support the notion that IDDM adolescents should be seen as a high-risk group for psychiatric disorders.