Miracle-dz/UniFAR-FTUs huggingface dataset:
The Moderating Effect of Negative Affectivity in the Procedural Justice-Job Satisfaction Relation.

Abstract We examined the potential moderating effect of negativeaffectivity in the relation between perceptions of proce-dural justice and job satisfaction in two studies. In thefirst study, we conducted a cross-sectional survey of 232individuals working for a Canadian public-sector organi-zation that was being partially privatized. In the secondstudy, we conducted a two-wave panel study of 173 uni-versity students participating in a co-operative educationwork term. In both studies, we found that the relationbetween procedural justice and job satisfaction wasstronger for those who were low in negative affectivitythan for those who were high in negative affectivity.These findings support the notion that employee disposi-tions influence the manner in which organizational fac-tors are perceived. In addition, these findings suggestthat fair procedures do not uniformly result in positiveorganizational outcomes (i.e., job satisfaction). Resume Nous nous sommes livres a deux etudes en vue d’exa-miner l’effet moderateur potentiel de l’affectivite negativesur la relation entre les perceptions de justice proceduraleet la satisfaction professionnelle. La premiere etude a con-siste d'une enquete transversale menee aupres de 232personnes au service d’un organisme public canadien envoie d’etre en partie privatise. Dans le cadre de la sec-onde, nous avons tenu un panel a deux volets composede 163 etudiants d’universite qui effectuaient un stageprofessionnel comme condition d’un programme d’alter-nance travail-etudes. Les resultats des deux etudes nousont amenes a constater que le rapport entre la justiceprocedurale et la satisfaction professionnelle etait plusforte chez ceux dont l’affectivite negative etait faible. Nosconstatations tendent a confirmer que la disposition del’employe influence sa perception des facteurs organisa-tionnels. De plus, elles laissent entendre que des proce-dures equitables ne conduisent pas a tout coup a desaboutissements organisationnels positifs (comme la satis-faction professionnelle).
Early Detection of Susceptibility to Acute Lung Inflammation by Molecular Imaging in Mice Exposed to Cigarette Smoke

Matrix metalloproteinases (MMPs) are extracellular proteolytic enzymes involved in acute lung inflammation in response to cigarette smoke exposure (CSE). We present the in vivo detection of MMP activity using a specific MMP-activatable, near-infrared, polymer-based proteolytic probe in strains of mice with different susceptibility to developing smoking-induced emphysema (susceptible mice, C57BL/6j, and resistant mice, 129S2/SvHsd) to characterize the distinctive profile of CSE-induced acute inflammation. In vivo imaging of pulmonary inflammation expressing MMPs revealed a significantly different median ratio twofold higher in smoker than in nonsmoker susceptible mice (C57BL/6j) and no significant differences between the smoker and the nonsmoker group in resistant mice (129S2/SvHsd). Ex vivo imaging of the lungs of each group of mice confirmed the same in vivo experiment results obtained for both strains of mice. In the biochemical study of lung tissue, the proteolytic signal colocalized with the endogenously expressed MMP protein levels, with MMP-9 levels that are 2.2 times higher than in the nonsmoke-exposed group in C57BL/6j mice and no significant differences in the 129S2/SvHsd mice. The MMP-activatable probe provides a useful reagent for the in vivo and ex vivo detection of MMP-selective proteolytic activity. We are able to distinguish between susceptible and resistant strains of mice in terms of the profile of MMP activity in the early stages of pulmonary disease.
Enhanced Stability of Ramipril in Nanoemulsion Containing Cremophor-EL: A Technical Note

Nanoemulsions are thermodynamically stable, transparent (or translucent) dispersions of oil and water stabilized by an interfacial film of surfactant and co-surfactant molecules having the droplet size less than 100 nm (1–3). Thermodynamic stability of nanoemulsions offer advantages over unstable dispersions, such as emulsions and suspensions, because they can be manufactured with little energy input (heat or mixing) and have a long shelf life (4). Ramipril, a potent antihypertensive drug, is almost completely converted to its active metabolite ramiprilat by hydrolytic cleavage of the ester group in the liver which has about six times angiotensin-converting enzyme (ACE) inhibitor activity of ramipril (1). Ramipril and ramiprilat inhibit ACE and lowers blood pressure effectively (5,6). Formulation of ramipril dosage form leads to a decrease in the assay of ramipril due to mechanical stress, compression, manufacturing processes, excipients, storage conditions, heat, moisture, and alkaline pH (7–9). Since the drug is highly lipophilic (log p 3.32), it was presumed that keeping it in lipophilic environment might increase its stability. In our experiments, when nanoemulsion formulation of ramipril was prepared using distilled water as an aqueous phase, ramipril was found to be degraded as its concentration decreased rapidly. A stable formulation of ramipril was claimed by a patent in which the drug was mixed with a physiologically tolerated buffer that ensures that a pH in the weakly acidic to weakly alkaline range is set up in a pharmaceutical formulation in the presence of moisture (10). Therefore, the aim of the present study was to perform pH degradation studies using different standard buffer solutions official in Indian Pharmacopoeia (I.P. 1996) as an aqueous phase in order to improve stability of ramipril in nanoemulsion formulation. The dose of ramipril varies between 2.5 and 20 mg, and the frequently prescribed dose is 5 mg for the adult. Therefore, for the present study, 5 mg/ml dose was selected for the development of nanoemulsion formulation.
Proposta de tipologia sobre alianças estratégicas

This article assumes that strategic alliances are a particular form of co-operation between firms, recognises the need to clarify the concept, and suggests elements of distinction with other forms of co-operation and inter-organizational relationships. Contributing for this effort of clarification, the article discusses and recognises some limitations in the literature on types of strategic alliances, and proposes a new typology of strategic alliances. The typology is based on three domains of cooperation which, in turn, are based on different activities. The empirical study was based on a survey to which replied 133 Portuguese industrial firms which participated in the European Union's Europartenariat programme. The main results of this study suggest that: (1) the studied firms have very positive indicators of co-operation; (2) the intensity of strategic alliances is associated with the firms' size; (3) the global intensity of strategic alliances varies according to each industry; (4) the importance of each type of strategic alliance varies according to each industry; (5) the importance of each type of strategic alliance varies according to the type of partner involved in the other side of the relationship.
Effects of nadir CD4 count and duration of human immunodeficiency virus infection on brain volumes in the highly active antiretroviral therapy era

Cerebral atrophy is a well-described, but poorly understood complication of human immunodeficiency virus (HIV) infection. Despite reduced prevalence of HIV-associated dementia in the highly active antiretroviral therapy (HAART) era, HIV continues to affect the brains of patients with chronic infection. In this study we examine patterns of brain volume loss in HIV-infected patients on HAART, and demographic and clinical factors contributing to brain volume loss. We hypothesized that nadir CD4+ lymphocyte count, duration of HIV infection, and age would be associated with reduced cortical volumes. Volumes of cortical and subcortical regions in 69 HIV-infected neuroasymptomatic (NA) individuals and 13 with at least mild acquired immunodeficiency syndrome (AIDS) dementia complex (ADC) were measured using voxel-based morphometry. Demographic and clinical factors (age, plasma HIV RNA level, current and nadir CD4 counts, duration of infection, central nervous system [CNS] penetration of antiretroviral regimen) along with their interactions were entered into a regression model selection algorithm to determine the final models that best described regional brain volumes. Relative to NA, individuals with ADC exhibited decreased total gray matter and parietal cortex volumes and increased total ventricular volumes. Final regression models showed overall cerebral volume, including gray and white matter volume and volumes of the parietal, temporal, and frontal lobes and the hippocampus, were most strongly associated with disease history factors (nadir CD4 and duration of infection). In contrast, basal ganglia volumes were related most strongly to current disease factors, most notably plasma HIV RNA. These findings indicate that individuals with a history of chronic HIV infection with previous episodes of severely impaired immune function, as reflected by reduced nadir CD4+ lymphocyte count, may be at greatest risk for cerebral atrophy. The pattern of HIV-associated brain loss may be changing from a subcortical to a cortical disease among patients who are largely asymptomatic on HAART.
On generating coherent multilingual descriptions of museum objects from Semantic Web ontologies

During the last decade, there has been a shift from developing natural language generation systems to developing generic systems that are capable of producing natural language descriptions directly from Web ontologies. To make these descriptions coherent and accessible in different languages, a methodology is needed for identifying the general principles that would determine the distribution of referential forms. Previous work has proved through cross-linguistic investigations that strategies for building coreference are language dependent. However, to our knowledge, there is no language generation methodology that makes a distinction between languages about the generation of referential chains. To determine the principles governing referential chains, we gathered data from three languages: English, Swedish and Hebrew, and studied how coreference is expressed in a discourse. As a result of the study, a set of language specific coreference strategies were identified. Using these strategies, an ontology-based multilingual grammar for generating written natural language descriptions about paintings was implemented in the Grammatical Framework. A preliminary evaluation of our method shows language-dependent coreference strategies lead to better generation results.
Signal recovery from incomplete and inaccurate measurements via ROMP

We demonstrate a simple greedy algorithm that can reliably recover a vector v ∈ R from incomplete and inaccurate measurements x = Φv + e. HereΦ is a N × d measurement matrix with N ≪ d, ande is an error vector. Our algorithm, Regularized Orthogonal Matching Pursuit (ROMP), seeks to close the gap between two major approaches to sparse recovery. It combines the speed and ease of implementation of the greedy methods with the strong guarantees of the convex programming methods. For any measurement matrix Φ that satisfies a Uniform Uncertainty Principle, ROMP recovers a signal v with O(n) nonzeros from its inaccurate measurements x in at mostn iterations, where each iteration amounts to solving a Least Squares Problem. The noise level of the recovery is proportional to √ log n‖e‖2. In particular, if the error terme vanishes the reconstruction is exact. This stability result extends naturally to the very accurat e recovery of approximately sparse signals.
Assessing the Impacts of Management Skill Training in Ghana and Kenya February 2010

In Sub-Saharan Africa, manufacturers operating in industrial clusters tend to lack basic business skills, and are very small in size and stagnant except when they are young. In the experience of East Asia, a number of industrial clusters have successfully overcome such difficulty by upgrading management and marketing as well as their products. We hypothesize that imparting basic skills in management and marketing to entrepreneurs in Sub-Saharan Africa will help them achieve such upgrading. In order to substantiate this hypothesis, this joint study with the World Bank carries out a randomized experiment in which entrepreneurs in our study sites in Kumasi, Ghana, and Nairobi, Kenya receive managerial training, and the improvements in their behaviors and business results are measured. The econometric analysis finds strong evidence of positive training impacts on business practices and performances.
Phosphoinositide-specific Inositol Polyphosphate 5-Phosphatase IV Inhibits Akt/Protein Kinase B Phosphorylation and Leads to Apoptotic Cell Death*

Phosphoinositide-specific inositol polyphosphate 5- phosphatase IV has the affinity for PI(3,4,5)P3 (K m = 0.65 μM) that is approximately 10-fold greater than the other inositol polyphosphate 5-phosphatases, which use this substrate including SHIP, OCRL, and 5ptase II, suggesting that it may be important in controlling intracellular levels of this metabolite. We created cell lines stably expressing the enzyme to study its effect on cell function. We found that overexpression of 5ptase IV in 293 cells caused the rapid depletion of both PI(4,5)P2 and PI(3,4,5)P3 in cells with corresponding increases in the products, PI(4)P and PI(3,4)P2, changing the balance of two phosphoinositol products of phosphoinositide 3-kinase, PI(3,4)P2 and PI(3,4,5)P3, in the cell. One of the targets of these phosphoinositides is the serine/threonine kinase Akt, which plays an important role in the control of apoptosis. We were able to address the relative roles of PI(3,4)P2 and PI(3,4,5)P3 in the activation of Akt by selective depletion of these phosphoinositides in cells stably transfected with 5ptase IV and inositol polyphosphate 4-phosphatase (4ptase I). In cells transfected with 4ptase I, the level of PI(3,4)P2 was reduced, and PI(3,4,5)P3 was increased. Expression of the two enzymes had the opposite effect on the phosphorylation of Akt in response to stimulation with growth factors or heat shock. Akt phosphorylation was inhibited in cells expressing 5ptase IV but increased in 4ptase I cells and correlated with the intracellular level of PI(3,4,5)P3 and not that of PI(3,4)P2. The inhibition of Akt phosphorylation in cells expressing 5ptase IV makes them highly susceptible to FAS-induced apoptosis, whereas overexpressing of the 4ptase I protects cells from apoptosis. Our results place 5ptase IV as a relevant biological regulator of PI3K/Akt pathway in cells.
Perceptual learning beyond retinotopic reference frame

Repetitive experience with the same visual stimulus and task can remarkably improve behavioral performance on the task. This well-known perceptual-learning phenomenon is usually specific to the trained retinal- or visual-field location, which is taken as an indication of plastic changes in retinotopic visual areas. In previous studies of perceptual learning, however, a change in stimulus location on the retina is accompanied by positional changes of the stimulus in nonretinotopic frames of reference, such as relative to the head and other objects. It is unclear, therefore, whether the putative location specificity is exclusively retinotopic or if it could also depend on nonretinotopic representation of the stimulus, which is particularly important for multisensory and sensorimotor integration as well as for maintenance of stable visual percepts. Here, by manipulating subjects’ gaze direction to control spatial and retinal locations of stimuli independently, we found that, when the stimulated retinal regions were held constant, the improvement with training in motion-direction discrimination of two successively displayed stimuli was restricted to the relative spatial position of the stimuli but independent of their absolute locations in head- and world-centered frame. These findings indicate location specificity of perceptual learning beyond retinotopic frame of reference, suggesting a pliable spatiotopic mechanism that can be specifically shaped by experience for better spatiotemporal integration of the learned stimuli.
A Social Recommendation Mechanism for Enhancing O2O E-Commerce

O2O business model synergize the efficiency improved from online retailing and value created from physical customer experience. Nowadays, while many O2O apps and services have been proposed, the study of the accuracy of customer targeting and the effectiveness of advertising in a dynamic environment are big challenges currently faced by O2O e-commerce. In this paper, we proposed a novel social recommendation mechanism for enhancing O2O e-commerce, by incorporating the techniques of context-awareness and social referral. The proposed mechanism could identify the most suitable ads for targeted users in a changing environment, and could significantly improve the effectiveness of advertising by taking the influence of friends into consideration.
3-D heart image reconstructed from MRI data

An outline of 3-D image reconstruction techniques for the left ventricle and the whole heart from MRI (magnetic resonance imaging) data is discussed. A method is proposed to reconstruct 3-D shapes of each part of the heart, i.e. left ventricle, left atrium, right ventricle, right atrium, aorta and pulmonary artery, in a voxel space using the cross-sectional images obtained by gated MRI of the heart on the transverse, coronal, and sagittal planes. The heart composed by putting together these six parts is superimposed on the original cross-sectional images. <<ETX>>
Association Study between Novel CYP26 Polymorphisms and the Risk of Betel Quid-Related Malignant Oral Disorders

BQ chewing may produce significant amounts of reactive oxygen species (ROS), resulting in oral mucosa damage, and ROS may be metabolized by CYP26 families. Because the CYP26 polymorphisms associated with malignant oral disorders are not well known, we conducted an association study on the associations between the single nucleotide polymorphisms (SNP) of CYP26 families and the risks of malignant oral disorders. BQ chewers with the CYP26A1 rs4411227 C/C+C/G genotype and C allele showed an increased risk of oral and pharyngeal cancer (adjusted odds ratio (aOR) = 2.30 and 1.93, respectively). The CYP26B1 rs3768647 G allele may be associated with oral and pharyngeal cancer (aOR = 3.12) and OPMDs (aOR = 2.23). Subjects with the rs9309462 CT genotype and C allele had an increased risk of oral and pharyngeal cancer (aOR = 9.24 and 8.86, respectively) and OPMDs (aOR = 8.17 and 7.87, respectively). The analysis of joint effects between the CYP26A1 rs4411227 and CYP26B1 rs3768647/rs9309462 polymorphisms revealed statistical significance (aOR = 29.91 and 10.03, respectively). Additionally, we observed a significant mRNA expression of CY26A1 and CYP26B1 in cancerous tissues compared with adjacent noncancerous tissues. Our findings suggest that novel CYP26 polymorphisms are associated with an increased risk of malignant oral disorders, particularly among BQ chewers.
Crystal structure of the ApbE protein (TM1553) from Thermotoga maritima at 1.58 Å resolution

Gye Won Han, S. Sri Krishna, Robert Schwarzenbacher, Daniel McMullan, Krzysztof Ginalski, Marc-André Elsliger, Scott M. Brittain, Polat Abdubek, Sanjay Agarwalla, Eileen Ambing, Tamara Astakhova, Herbert Axelrod, Jaume M. Canaves, Hsiu-Ju Chiu, Michael DiDonato, Slawomir K. Grzechnik, Joanna Hale, Eric Hampton, Justin Haugen, Lukasz Jaroszewski, Kevin K. Jin, Heath E. Klock, Mark W. Knuth, Eric Koesema, Andreas Kreusch, Peter Kuhn, Mitchell D. Miller, Andrew T. Morse, Kin Moy, Edward Nigoghossian, Sylvia Oommachen, Jie Ouyang, Jessica Paulsen, Kevin Quijano, Ron Reyes, Chris Rife, Glen Spraggon, Raymond C. Stevens, Henry van den Bedem, Jeff Velasquez, Xianhong Wang, Bill West, Aprilfawn White, Guenter Wolf, Qingping Xu, Keith O. Hodgson, John Wooley, Ashley M. Deacon, Adam Godzik, Scott A. Lesley, and Ian A. Wilson* Joint Center for Structural Genomics Stanford Synchrotron Radiation Laboratory, Stanford University, Menlo Park, California University of California, San Diego, La Jolla, California Genomics Institute of the Novartis Research Foundation, San Diego, California The Scripps Research Institute, La Jolla, California Interdisciplinary Centre for Mathematical and Computational Modelling, Warsaw University, Warsaw, Poland
Defecting or Not Defecting: How to “Read” Human Behavior during Cooperative Games by EEG Measurements

Understanding the neural mechanisms responsible for human social interactions is difficult, since the brain activities of two or more individuals have to be examined simultaneously and correlated with the observed social patterns. We introduce the concept of hyper-brain network, a connectivity pattern representing at once the information flow among the cortical regions of a single brain as well as the relations among the areas of two distinct brains. Graph analysis of hyper-brain networks constructed from the EEG scanning of 26 couples of individuals playing the Iterated Prisoner's Dilemma reveals the possibility to predict non-cooperative interactions during the decision-making phase. The hyper-brain networks of two-defector couples have significantly less inter-brain links and overall higher modularity—i.e., the tendency to form two separate subgraphs—than couples playing cooperative or tit-for-tat strategies. The decision to defect can be “read” in advance by evaluating the changes of connectivity pattern in the hyper-brain network.
Shared Entrepreneurship: Toward an Empowering, Ethical, Dynamic, and Freedom-Based Process of Collaborative Innovation

Shared entrepreneurship1 (SE) is becoming recognized as an organizational model that can succeed in a rapidly changing global marketplace where the hierarchical commandand-control model seems less apt in today’s environment (Alperovitz, 2013; Hamel, 2007; Kinicki, 2008; Kruse, Freeman, & Blasi, 2010). Hierarchical command-and-control stifles innovation and often fails to reward those who are responsible for an innovation (Shipper & Manz; 1993). Innovation— whether product, process, market or organizational—is the driver of success (Avermaete, Viaene, Morgan, & Crawford, 2003). That has always been true, but it is more critical today than ever before because of rapidly changing technological advances and consumer preferences. The academic evidence is sketchy because shared entrepreneurship is an emerging and growing practice, although a limited number of organizations have been using it for 50 or more years. Those that do practice it appear to have a better chance of survival than those that don’t (e.g., Olson, 2013). How shared entrepreneurship and related concepts such as shared ownership, shared governance, and shared leadership are associated with the success of organizations has not become a significant part of the academic literature (Shipper et al., 2013). Thus, this White Paper was derived primarily from hundreds of hours of formal interviews, conversations, and observations that were conducted in 13 organizations that practice shared entrepreneurship. The sample was quite diverse, from highto low-technology industries, from local to international firms, from small (fewer than 100 employees) to large (more than 6000) firms, and from production to service firms. They were selected initially because they practiced shared ownership. Over
Hua-type integrals over unitary groups and over projective limits of unitary groups

We discuss some natural maps from a unitary group U(n) to a smaller group U(n-m) (these maps are versions of the Livshic characteristic function). We calculate explicitly the direct images of the Haar measure under some maps. We evaluate some matrix integrals over classical groups and some symmetric spaces (values of the integrals are products of Gamma-functions). These integrals generalize Hua Loo Keng integrals. We construct inverse limits of unitary groups equipped with analogues of the Haar measure and evaluate some integrals over these inverse limits.