Miracle-dz/UniFAR-FTUs huggingface dataset:
HA-CIDS: A Hierarchical and Autonomous IDS for Cloud Systems

Cloud computing is an attractive model that provides the delivery of on-demand computing resources over the Internet and on a pay-for-use basis. However, while intruders may exploit clouds for their advantage, most IDS solutions are not suitable for cloud environments. This paper presents a hierarchical and autonomous cloud based intrusion detection system, HA-CIDS. The framework continuously monitors and analyzes system events and computes the security and risk parameters. An autonomous controller receives security parameters computed by the framework and selects the most appropriate response to protect the cloud against detected attacks, as well as recover any corrupted data or affected services. Beside autonomous response to detected attacks, HA-CIDS has several autonomous capabilities to provide self-resilience and fault tolerance. We developed a testbed to evaluate the performance and accuracy of the framework. The architecture, design, and deployment of HACIDS are given in this paper.
Differences in Circulating Non-Transferrin-Bound Iron after Oral Administration of Ferrous Sulfate, Sodium Iron EDTA, or Iron Polymaltose in Women with Marginal Iron Stores

Background The adverse interactions between iron supplements and malaria have driven the assessment of new therapeutic options for anemia prophylaxis in areas holoendemic for falciparum malaria. Objective To determine the responses of circulating non-transferrin-bound iron (NTBI) and plasma iron to three different oral iron compounds—ferrous sulfate, sodium iron ethylenediaminetetraacetate (NaFeEDTA), and iron polymaltose (IPM)—in women with marginal iron stores. Methods Serum samples from 10 Guatemalan women with marginal iron stores were collected every 90 minutes over a period of 270 minutes, after the individually randomized administration of 100 mg of iron from each of the three studied iron compounds or water alone. Serum iron concentration was quantified by the ferrozine method, and circulating NTBI concentration was determined with a fluorometric competitive binding assay. Kinetic responses and maximal cumulative changes in serum concentrations of iron and NTBI were compared between the four treatments. Comparison was made with data from the same protocol in iron-adequate men. Results The serum iron and NTBI responses to ferrous sulfate were significantly greater than those to water and the other two iron compounds. Serum iron responses to IPM did not differ from those to water alone. Conclusions The administration of the two “slow-release” iron compounds, NaFeEDTA and IPM, resulted in a highly significant suppression of the appearance of NTBI in the circulation in the postsupplement period. These two bioavailable forms of iron supplement could represent a safe option for supplementation in malarial areas. The slope of the iron—NTBI relationship is steeper in men than in women.
Guideline for the management of fever and neutropenia in children with cancer and/or undergoing hematopoietic stem-cell transplantation.

PURPOSE To develop an evidence-based guideline for the empiric management of pediatric fever and neutropenia (FN). METHODS The International Pediatric Fever and Neutropenia Guideline Panel is a multidisciplinary and multinational group composed of experts in pediatric oncology and infectious disease as well as a patient advocate. The Panel was convened for the purpose of creating this guideline. We followed previously validated procedures for creating evidence-based guidelines. Working groups focused on initial presentation, ongoing management, and empiric antifungal therapy. Each working group developed key clinical questions, conducted systematic reviews of the published literature, and compiled evidence summaries. The Grades of Recommendation Assessment, Development, and Evaluation approach was used to generate summaries, and evidence was classified as high, moderate, low, or very low based on methodologic considerations. RESULTS Recommendations were made related to initial presentation (risk stratification, initial evaluation, and treatment), ongoing management (modification and cessation of empiric antibiotics), and empiric antifungal treatment (risk stratification, evaluation, and treatment) of pediatric FN. For each recommendation, the strength of the recommendation and level of evidence are presented. CONCLUSION This guideline represents an evidence-based approach to FN specific to children with cancer. Although some recommendations are similar to adult-based guidelines, there are key distinctions in multiple areas. Implementation will require adaptation to the local context.
Comparison of successive transition states for folding reveals alternative early folding pathways of two homologous proteins

The energy landscape theory provides a general framework for describing protein folding reactions. Because a large number of studies, however, have focused on two-state proteins with single well-defined folding pathways and without detectable intermediates, the extent to which free energy landscapes are shaped up by the native topology at the early stages of the folding process has not been fully characterized experimentally. To this end, we have investigated the folding mechanisms of two homologous three-state proteins, PTP-BL PDZ2 and PSD-95 PDZ3, and compared the early and late transition states on their folding pathways. Through a combination of Φ value analysis and molecular dynamics simulations we obtained atomic-level structures of the transition states of these homologous three-state proteins and found that the late transition states are much more structurally similar than the early ones. Our findings thus reveal that, while the native state topology defines essentially in a unique way the late stages of folding, it leaves significant freedom to the early events, a result that reflects the funneling of the free energy landscape toward the native state.
Overexpression of PD-L2 is associated with shorter relapse-free survival in patients with malignant salivary gland tumors

Objectives PD-1/PD-L1 and CTLA-4 have been investigated and are thought to play an important role in tumor evasion. This study aimed to investigate expression patterns of immune-related molecules, and their clinical impacts in malignant salivary gland tumors. Patients and methods We performed immunohistochemical staining for PD-L1, PD-L2, CTLA-4, PD-1, and CD8+ tumor-infiltrating lymphocytes in 70 malignant salivary gland tumors. Protein expression was assessed by H-score by multiplying the staining intensity by the percentage of cells with positive staining. Results The tumors comprised mucoepidermoid carcinomas (38.6%), adenoid cystic carcinomas (21.4%), salivary duct carcinomas (15.7%), and others. In malignant salivary gland tumors, PD-L2 expression was high, while expression of PD-L1 was relatively low in terms of the percentage of positively stained cells and the staining intensity. In univariate analysis, PD-L2 expression (H-score <1 vs ≥1), PD-1 (H-score <1 vs ≥1), and CD8+ tumor-infiltrating lymphocytes (H-score <1 vs ≥1) were significant prognostic factors. In multivariate analysis, low PD-L2 expression (H-score <1) was independently associated with shorter relapse-free survival (hazard ratio =6.514; 95% confidence interval, 1.2–36.2; P=0.032). Conclusion In summary, PD-L2 is potentially an important biomarker in malignant salivary gland tumors, especially in regard to relapse.
Do Distributed Semantic Models Dream of Electric Sheep? Visualizing Word Representations through Image Synthesis

We introduce the task of visualizing distributed semantic representations by generating images from word vectors. Given the corpus-based vector encoding the word broccoli, we convert it to a visual representation by means of a cross-modal mapping function, and then use the mapped representation to generate an image of broccoli as “dreamed” by the distributed model. We propose a baseline dream synthesis method based on averaging pictures whose visual representations are topologically close to the mapped vector. Two experiments show that we generate dreams that generally belong to the the right semantic category, and are sometimes accurate enough for subjects to distinguish the intended concept from a related one.
Effects of Previous Crop Management, Fertilization Regime and Water Supply on Potato Tuber Proteome and Yield

There is increasing concern about the sustainability and environmental impacts of mineral fertilizer use in agriculture. Increased recycling of nutrients via the use of animal and green manures and fertilizers made from domestic organic waste may reduce reliance on mineral fertilizers. However, the relative availability of nutrients (especially nitrogen) is lower in organic compared to mineral fertilizers, which can result in significantly lower yields in nutrient demanding crops such as potato. It is therefore important to gain a better understanding of the factors affecting nutrient use efficiency (yield per unit fertilizer input) from organic fertilizers. Here we show that (a) previous crop management (organic vs. conventional fertilization and crop protection regimes), (b) organic fertilizer type and rate (composted cattle manure vs. composted chicken manure pellets) and (c) watering regimes (optimized and restricted) significantly affected leaf chlorophyll content, potato tuber N-concentration, proteome and yield. Protein inference by gel matching indicated several functional groups significantly affected by previous crop management and organic fertilizer type and rate, including stress/defense response, glycolysis and protein destination and storage. These results indicate genomic pathways controlling crop responses (nutrient use efficiency and yield) according to contrasting types and rates of organic fertilizers that can be linked to the respective encoding genes.
Vac8p, an Armadillo Repeat Protein, Coordinates Vacuole Inheritance With Multiple Vacuolar Processes

Vac8p, an armadillo (ARM) repeat protein, is required for multiple vacuolar processes. It functions in vacuole inheritance, cytoplasm‐to‐vacuole protein targeting pathway, formation of the nucleus–vacuole junction and vacuole–vacuole fusion. These functions each utilize a distinct Vac8p‐binding partner. Here, we report an additional Vac8p function: caffeine resistance. We show that Vac8p function in caffeine resistance is mediated via a newly identified Vac8p‐binding partner, Tco89p. The interaction between Vac8p and each binding partner requires an overlapping subset of Vac8p ARM repeats. Moreover, these partners can compete with each other for access to Vac8p. Furthermore, Vac8p is enriched in three separate subdomains on the vacuole, each with a unique binding partner dedicated to a different vacuolar function. These findings suggest that a major role of Vac8p is to spatially separate multiple functions thereby enabling vacuole inheritance to occur concurrently with other vacuolar processes.
Pattern of Pediatric Seizures at Al-Arish Central Hospital - North Sinai

Background: Seizures represent a prevalent etiology for pediatric hospitalization, resulting in notable morbidity and mortality. Seizures are temporary manifestations arising from an atypical, heightened, or synchronized neural activity within the cerebral cortex. Approximately 2% of emergency department visits are attributed to them. Aim of the Study : This study was to delineate the seizure presentation among patients admitted to the Pediatric department at Al-Arish Central Hospital in North Sinai and to contrast the findings with those of comparable studies conducted nationally and internationally. Furthermore, it provides descriptive information essential for planning future research. Patients and Methods: The present study comprised a cohort of 125 pediatric patients diagnosed with seizures who were admitted to the Pediatric department at Al-Arish Central Hospital in North Sinai for one year, from June 2019 to May 2020. The age range of the individuals was from two months to eighteen years. Results: The etiological analysis conducted indicated that epilepsy was the most prevalent cause of seizures in children, accounting for 45 cases (36.0%). Febrile convulsion was identified as the second most common cause, with 39 cases (31.2%) observed. Valproic acid (62.5%) and Levetiracetam (45.0%) were the prevalent antiepileptic drugs employed. Conclusions: Seizure is a prevalent reason for hospitalization among children, particularly those under the age of five, at the pediatric department of Al Arish Central Hospital in North Sinai. Generalized tonic-clonic seizures are more frequent and have diverse etiologies. Epilepsy was identified as the predominant etiology for seizures, with febrile seizures following as the subsequent cause. The most prevalent types of symptomatic seizures associated with infectious causes of the central nervous system were those attributed to viral encephalitis.
What's Changed?

The authors outline cross-sectional studies (across time and age) of the effects of the political changes in South Africa on the intergroup orientations of adolescents, as well as their orientations to the new democracy. The study was undertaken between 1992 (before the end of apartheid) and 1996 (after apartheid), with 14-year-old and 17-year-old high school students from formerly designated Black, Coloured, White and Indian population groups. Participants completed Duckitt's Subtle Racism Anti-Black Scale, a Repertory Grid following Kelly and measures of adjustment to political change. The results indicate that levels of anti-Black African racism, particularly among Whites previously advantaged under apartheid, were high in both years, and have increased with the emergence of the new state. The study found in addition, that orientations towards the new political dispensation were related to levels of racism. Some evidence of outgroup preference for Whites was evident among Black participants, while a degree of outgroup rejection of other Black groups was also evident among these groups in 1996.
Using a Productivity‐based Physician Compensation Program at an Academic Health Center: A Case Study

Purpose With increased budget constraints, academic health centers (AHCs) have turned their focus on physician compensation. While many AHCs are concerned that compensation programs driven primarily by revenue generation will have a negative impact on their academic mission, little information is available to support this. The authors examined the effects on teaching and clinical productivity of an innovative compensation program for pediatrics primary care faculty at an AHC and related those effects to national standards for productivity. Method A baseline productivity and compensation assessment was conducted for a group of 35 academic general pediatricians. The data were compared with Medical Group Management Association (MGMA) figures for general pediatricians. A productivity-based faculty compensation program using the work component of the relative-value unit (RVU) as the measure of productivity was designed and implemented. Productivity and compensation were measured after the first year of the program and compared with the baseline assessment. The numbers of hours precepting students and residents and the students' evaluations of their clinical experiences before and after implementation of the program were compared. Results The baseline assessment showed that over half of the faculty had productivity that fell below the MGMA 25th percentile, while the majority had compensation that exceeded this percentile. After implementation of the compensation program, 89% of the faculty increased their clinical productivity. The times faculty spent precepting and students' evaluations before and after program implementation were unchanged. Conclusions Successful productivity-based physician compensation programs can be developed for AHCs.
Cultural Relational Leaders: Unraveling, Understanding, and Utilizing Narratives in Leadership Practice

The arguments for using narratives to organize one's leadership practice are helpful in that they justify and organize many of the activities that go into the leader's professional and personal life. This paper explores the complex nature of narratives in a professional setting and the manner in which leaders can use the therapeutic methodology of cultural relational psychology to address multiple meanings embedded in narratives. People narrate their own subjective and embodied realities and reveal themselves metaphorically and symbolically through the stories they tell. The author outlines methods that leaders can use in the context of giving and sharing narratives; including empathic attunement, contextualization, relationship authenticity, using conflicts and tensions to make relationships stronger, understanding why people feel disconnected or disempowered, and honoring individual differences.
Large-Scale Semantic Indexing of Biomedical Publications

Automated annotation of scientiﬁc publications in real-world digital libraries requires dealing with challenges such as large number of concepts and training examples, multi-label training examples and hierarchical structure of concepts. BioASQ is a European project that contributes a large-scale biomedical publications corpus for working on these challenges. This paper documents the participation of our team to the large-scale biomedical semantic indexing task of BioASQ.
The Basis of Social Conflict

Inasmuch as economics is commonly defined as the science of wealth, and wealth as the sum of things which have value, it would seem that value is the central concept of the science. But value, as the economist uses the term, depends upon scarcity and never exists without it. Moreover, assuming only that it is appropriable, everything which is scarce has value. That is, with the qualification already named, value and scarcity are always found together and never separated. Therefore, one might define wealth as the sum of appropriable things which are scarce. Scarcity means insufficiency to satisfy wants. However abundant a thing may be, speaking absolutely, if there is not as much as is wanted, it is scarce; and however rare it may be, speaking absolutely, if there is as much as, or more than, is Wanted, it is not scarce. So much by way of definition. The fact of scarcity implies a lack of harmony, or a conflict, between man and nature. The fact that man has wants which nature does not completely satisfy means nothing if not that man is out of harmony, to that extent at least, with his material environment. Productive labor is merely man's way of trying to improve these imperfect relations. But he not only labors to increase the supply of things which are scarce, he must also economize in their use, that is, he must try to make them go as far as possible. That is what it means to economize. Things which are scarce, therefore, make up the category of economic goods, or wealth-to return to the point from which we started. These are the only things toward which our habitual attitude is an economic one. That there is a deeper harmony lying hidden somewhere beneath this glaring disharmony between man and nature is quite possible. At least no one can positively assert that it is not so.
Latino Bilingual Teachers: The Struggle to Sustain an Emancipatory Pedagogy in Public Schools.

This study examines how socially conscious bilingual Latino educators, specifically prepared to teach underserved children, resist multiple layers of hegemonic structures. The participants are five beginning Spanish bilingual teachers who teach in urban and semi-rural elementary schools. The study explores how their resistance unfolds as they develop and become critical educators and how their presence in schools provides children with the potential to develop social consciousness. This participatory research design uses dialogue as a tool to identify the problem, to facilitate the emergence of voice, to construct new knowledge, and to take action. Several themes surface: (1) the isolation of bilingual teachers, (2) the manifestations of power relations among students, (3) the use of a culturally bound pedagogy, (4) the countering of hidden curriculum through critical pedagogy, and (5) development of identity and voice for both students and teachers. The participating Latino teachers linked their social c.
Concurrent validity of a WAIS-R seven-subtest short form in patients with brain impairment

The concurrent validity of a Wechsler Adult Intelligence Scale-Revised (WAIS-R) seven-subtest short form was examined in 138 patients with closed-head injuries and 49 patients with presumed dementia. In patients with closed-head injuries, the average short form IQ score was within 1 point of the actual Verbal, Performance, and Full Scale IQ (VIQ, PIQ, and FSIQ) scores. The validity coefficients for these patients ranged from.90 to.95. In patients with presumed dementia, the short form underestimated the average VIQ by nearly 5 points and the average FSIQ by 3.5 points. However, the validity coefficients for these patients were uniformly high (.91 to to.95 ). Examination of the frequency distributions revealed that there was a percentage of patients whose short form IQs and actual IQs were highly discrepant. Research designed to determine the variables that reduce the accuracy of the short form in clinical populations is needed.
Network covert channel analysis based on the density multilevel two segment clustering

On the problem of covert channel detection, the traditional detection algorithms exist specific covert channel blind area, or it is useful for some kind of covert channel detection but ignore other covert channels. In order to solve this problem, in this paper proposes network covert channel analysis method based on the density multilevel two segment clustering. Firstly, the problem of covert channel in complex network is studied, and its mathematical model and data feature extraction are presented; Secondly, based on hierarchical clustering and design its multilevel aggregation improved form using the given complex network channel coarsening clustering results, at the same time in each layer of coarse channel and the results of detection, using density clustering algorithm to implement complex network covert channel detection and thinning and improve the prediction accuracy. Finally, the proposed algorithm can detect the complex network covert channel quickly and accurately when the noise is no higher than 20%.
High Educational Expectations and Low Achievement: Stability of Educational Goals Across Adolescence

Abstract Data from the National Education Longitudinal Study of 1988 were used to investigate variables that predicted stability of adolescents' postsecondary educational expectations from Grade 8 to 2 years after high school. The study included students who had early expectations for at least a bachelor's degree as well as 8th-grade reading or mathematics test scores that were below the median. All participants had high early expectations and comparatively low early achievement. Six years later, approximately 76% of the participants still had high expectations, whereas 24% of them no longer expected to earn a bachelor's degree. Results provide support for the addition of variables to the social cognitive model of educational achievement when predicting long-term educational expectations and attainment.