Miracle-dz/UniFAR-FTUs huggingface dataset:
Developing Emotional Intelligence for Sustained Student Success

The dire educational situation in South Africa has urged researchers to investigate possible predictors of academic success. There seems to be an increasing emphasis on non–cognitive factors that might play a role in determining the academic performance of students. In this study various unique challenges first-year students face were underlined, followed by possible key psychological resources needed to overcome such challenges. These resources include self-regulatory skills (i.e. self-leadership and emotional regulation), psychological well-being and constructive self-efficacy beliefs that could all ultimately help determine an individual’s academic success. It was hypothesised that Emotional Intelligence (EI) are central to these psychological resources and play a crucial role in the adaption and performance of first-year students in higher educational institutions. In this study an EI development programme was therefore implemented in order to evaluate whether it is possible to provide students with a powerful resource reservoir (i.e. high EI capabilities) in order to empower them to acquire additional personal and psychological resource (i.e. academic self-leadership, academic self-efficacy and well-being) that are needed to attain academic success. The findings of this study revealed that the EI development programme succeeded in elevating students’ EI, which also led to moderate improvements in their psychological well-being (i.e. less perceived stress), as well as the enhancement of their academic self-leadership (ASL) and academic self-efficacy (ASE) skills and abilities. Institutes of higher education should therefore rethink the emphasis they place on cognitive abilities alone and consider the strategy of also providing opportunities to enhance noncognitive predictors of academic success. For example, by implementing EI development programmes, such as the one tested in this research, students have a greater chance of developing the necessary self-direction and self-regulation skills necessary to reach academic greatness which, most probably, will also facilitate better employability and career success. Stellenbosch University http://scholar.sun.ac.za
Analysis of Murine Hepatitis Virus Strain A59 Temperature-Sensitive Mutant TS-LA6 Suggests that nsp10 Plays a Critical Role in Polyprotein Processing

ABSTRACT Coronaviruses are the largest RNA viruses, and their genomes encode replication machinery capable of efficient replication of both positive- and negative-strand viral RNAs as well as enzymes capable of processing large viral polyproteins into putative replication intermediates and mature proteins. A model described recently by Sawicki et al. (S. G. Sawicki, D. L. Sawicki, D. Younker, Y. Meyer, V. Thiel, H. Stokes, and S. G. Siddell, PLoS Pathog. 1:e39, 2005), based upon complementation studies of known temperature-sensitive (TS) mutants of murine hepatitis virus (MHV) strain A59, proposes that an intermediate comprised of nsp4 to nsp10/11 (∼150 kDa) is involved in negative-strand synthesis. Furthermore, the mature forms of nsp4 to nsp10 are thought to serve as cofactors with other replicase proteins to assemble a larger replication complex specifically formed to transcribe positive-strand RNAs. In this study, we introduced a single-amino-acid change (nsp10:Q65E) associated with the TS-LA6 phenotype into nsp10 of the infectious clone of MHV. Growth kinetic studies demonstrated that this mutation was sufficient to generate the TS phenotype at permissive and nonpermissive temperatures. Our results demonstrate that the TS mutant variant of nsp10 inhibits the main protease, 3CLpro, blocking its function completely at the nonpermissive temperature. These results implicate nsp10 as being a critical factor in the activation of 3CLpro function. We discuss how these findings challenge the current hypothesis that nsp4 to nsp10/11 functions as a single cistron in negative-strand RNA synthesis and analyze recent complementation data in light of these new findings.
Perceived Participation and Health-Related Quality of Life in 85 Year Olds in Sweden

This study explores how 85 year olds in Sweden perceive participation and autonomy in their life situations in relation to health-related quality of life and gender. A postal questionnaire included questions on sociodemographics, social network, assistive technology, community assistance, and the EQ-5D. During a home visit, an occupational therapist evaluated perceived participation and autonomy using the Impact on Participation and Autonomy Questionnaire. Most perceived their participation as sufficient. Women had greater limitations than men in indoor and outdoor autonomy. Only a few individuals reported many or severe problems with participation, mainly in mobility and leisure. Not having friends nearby, no close contact with neighbors, and living in community housing increased the risk of perceived problems. Sufficient participation was positively associated with higher health-related quality of life, and facilitating participation is an area of interest for occupational therapists.
On maximizing welfare when utility functions are subadditive

We consider the problem of maximizing welfare when allocating m items to n players with subadditive utility functions. Our main result is a way of rounding any fractional solution to a linear programming relaxation to this problem so as to give a feasible solution of welfare at least half that of the value of the fractional solution. This approximation ratio of 1/2 improves over an Ω(1/log m) ratio of Dobzinski, Nisan and Schapira [STOC 2005]. We also show an approximation ratio of 1 - 1/e when utility functions are fractionally subadditive. A result similar to this last result was previously obtained by Dobzinski and Schapira [Soda 2006], but via a different rounding technique that requires the use of a so called "XOS oracle". The randomized rounding techniques that we use are oblivious in the sense that they only use the primal solution to the linear program relaxation, but have no access to the actual utility functions of the players. This allows us to suggest new incentive compatible mechanisms for combinatorial auctions, extending previous work of Lavi and Swamy [FOCS 2005].
A Multipath Routing Protocol Based on Clustering and Ant Colony Optimization for Wireless Sensor Networks

For monitoring burst events in a kind of reactive wireless sensor networks (WSNs), a multipath routing protocol (MRP) based on dynamic clustering and ant colony optimization (ACO) is proposed. Such an approach can maximize the network lifetime and reduce the energy consumption. An important attribute of WSNs is their limited power supply, and therefore some metrics (such as energy consumption of communication among nodes, residual energy, path length) were considered as very important criteria while designing routing in the MRP. Firstly, a cluster head (CH) is selected among nodes located in the event area according to some parameters, such as residual energy. Secondly, an improved ACO algorithm is applied in the search for multiple paths between the CH and sink node. Finally, the CH dynamically chooses a route to transmit data with a probability that depends on many path metrics, such as energy consumption. The simulation results show that MRP can prolong the network lifetime, as well as balance of energy consumption among nodes and reduce the average energy consumption effectively.
A novel single-stage LED driver with coupled inductors and interleaved PFC

This paper proposes a novel single-stage light-emitting diode (LED) driver with coupled inductors and interleaved power-factor correction (PFC), suitable for streetlight applications. The presented LED driver integrates an interleaved boost PFC converter with coupled inductors and a half-bridge-type series-resonant converter cascaded with a full-bridge rectifier into a single-stage power-conversion circuit. Coupled inductors inside the interleaved boost PFC converter sub-circuit are designed to operate in discontinuous-conduction mode (DCM) for achieving input-current shaping, and the half-bridge-type series-resonant converter cascaded with a full-bridge rectifier is designed for obtaining zero-voltage switching (ZVS) on two power switches to reduce their switching losses. Analysis of operational modes and design equations for the presented LED driver are described and included. In addition, the proposed driver features high power factor, low total-harmonic distortion (THD) of input current and soft-switching. Finally, a prototype 165W-rated LED driver is developed and tested with a utility-line input voltage of 110V. Satisfactory outcomes from experimental results demonstrate the feasibility of the proposed circuit.
Balancing Hamiltonian and Jeffersonian Contradictions Within Organizations

This article describes how institutions get infused with competing logics and analyzes how such competing logics might aid the design of contemporary organizations. It does so by exploring the contrasting views of American founders Alexander Hamilton and Thomas Jefferson on the issues they confronted in the years leading up to and after the United States' independence from the British. Their views have had a lasting influence on the character and efficacy of the U.S. government. Although Hamilton and Jefferson contemplated issues related to the governance of the United States, the authors argue that their writings offer insights that can be useful to students of organizational design. They identify four influential ideas from the writings of Hamilton and Jefferson and discuss their implications for organizational design.
Naive + Naive = Smart Bayes ?

Naive Bayes is a well-known and studied algorithm both in statistics and machine learning. Bayesian learning algorithms represent each concept with a single probabilistic summary. This paper presents a novel method to construct a hierarchy of Naive Bayes classifiers, in which two levels of Naive Bayes classifiers are applied. The underlying motivation is to try to correct the mistakes made by a single Naive Bayes classifier applying Naive Bayes again over its output. We have tested this algorithm over 20 UCI datasets. The results suggest that the chance of obtaining a better performance than with the original Naive Bayes approach are much greater than the opposite.
Characterization of a eukaryotic type serine/threonine protein kinase and protein phosphatase of Streptococcus pneumoniae and identification of kinase substrates

Searching the genome sequence of Streptococcus pneumoniae revealed the presence of a single Ser/Thr protein kinase gene stkP linked to protein phosphatase phpP. Biochemical studies performed with recombinant StkP suggest that this protein is a functional eukaryotic‐type Ser/Thr protein kinase. In vitro kinase assays and Western blots of S. pneumoniae subcellular fractions revealed that StkP is a membrane protein. PhpP is a soluble protein with manganese‐dependent phosphatase activity in vitro against a synthetic substrate RRA(pT)VA. Mutations in the invariant aspartate residues implicated in the metal binding completely abolished PhpP activity. Autophosphorylated form of StkP was shown to be a substrate for PhpP. These results suggest that StkP and PhpP could operate as a functional pair in vivo. Analysis of phosphoproteome maps of both wild‐type and stkP null mutant strains labeled in vivo and subsequent phosphoprotein identification by peptide mass fingerprinting revealed two possible substrates for StkP. The evidence is presented that StkP can phosphorylate in vitro phosphoglucosamine mutase GlmM which catalyzes the first step in the biosynthetic pathway leading to the formation of UDP‐N‐acetylglucosamine, an essential common precursor to cell envelope components.
Child Care, Work, and Depressive Symptoms Among Low-Income Mothers

Focusing on social factors associated with increased depressive symptoms among working mothers living in poor urban neighborhoods, this study investigates the effects of welfare participation, employment conditions, and child care on women's emotional well-being. The authors use new data from the Philadelphia Survey of Child Care and Work. Hierarchical regression analyses reveal minimal effects of welfare participation on depressive symptoms. However, women's employment characteristics and child care problems were significantly related to emotional well-being. Interaction effects between child care and employment were also explored. Mothers who had concerns about child care were more likely to report depressive symptoms when they had good-quality jobs (higher wages) or when they had only one job or were not unemployed.
Immunoisolation of Hybrid Liver Support Systems by Semipermeable Membranes

Immunoisolation of hybrid liver support systems (LSS) utilizing suitable semipermeable membranes as an immune barrier enables neither immunocompetent cytotoxic factors to cause damage to the hepatocytes in the bioreactor nor xenogenic hepatocyte products to cause immunological side effects in patients. To determine the capability of membranes as an immune barrier, 6 flat membranes were investigated: Cuprophan (C-100), cut-off MW 1000, Cuprophan (C-240), cut-off MW 10,000, Polypropylen hydrophilic and hydrophobic (PPhi, PPho), cut-off MW 500,000-1,000,000, Polysulfon (PS), cut-off MW 1,000,000, Polyamid (PA), cut-off beyond MW 1,000,000. The permeability of the membranes to plasma factors and liver protein fractions (LP) was studied by routine biochemical methods and gel electrophoresis. In a second study, pigs (n=7) were immunised by LP after membrane passage. The results showed PA, PS, and PPhi to be completely permeable for plasma factors and LP, C-100 and C-240 for urophanic substances, and C-240 again for LP under MW 14.000. All 7 pig sera studied by Western blot discovered pre-formed xenoreactive natural IgG-antibodies (NAB) against human liver antigen (AG) with MW 26.000. AB de-novo-synthesis was demonstrated for AG with MW 45.000. No AB-synthesis was induced for epitopes under MW 26,000. These results suggest that limiting the cut-off of bioreactor outflow membranes to MW < 26,000 could avoid immunological side effects to patients.
Magnitude of Morning Surge in Blood Pressure Is Associated with Sympathetic but Not Cardiac Baroreflex Sensitivity

The ability of the arterial baroreflex to regulate blood pressure may influence the magnitude of the morning surge in blood pressure (MSBP). The aim was to investigate the relationships between sympathetic and cardiac baroreflex sensitivity (BRS) and the morning surge. Twenty-four hour ambulatory blood pressure was recorded in 14 young individuals. The morning surge was defined via the pre-awakening method, which is calculated as the difference between mean blood pressure values 2 h before and 2 h after rising from sleep. The mean systolic morning surge, diastolic morning surge, and morning surge in mean arterial pressures were 15 ± 2, 13 ± 1, and 11 ± 1 mmHg, respectively. During the laboratory protocol, continuous measurements of blood pressure, heart rate, and muscle sympathetic nerve activity (MSNA) were made over a 10-min period of rest. Sympathetic BRS was quantified by plotting MSNA burst incidence against diastolic pressure (sympathetic BRSinc), and by plotting total MSNA against diastolic pressure (sympathetic BRStotal). Cardiac BRS was quantified using the sequence method. The mean values for sympathetic BRSinc, sympathetic BRStotal and cardiac BRS were −1.26 ± 0.26 bursts/100 hb/mmHg, −1.60 ± 0.37 AU/beat/mmHg, and 13.1 ± 1.5 ms/mmHg respectively. Significant relationships were identified between sympathetic BRSinc and the diastolic morning surge (r = 0.62, p = 0.02) and the morning surge in mean arterial pressure (r = 0.57, p = 0.03). Low sympathetic BRS was associated with a larger morning surge in mean arterial and diastolic blood pressure. Trends for relationships were identified between sympathetic BRStotal and the diastolic morning surge (r = 0.52, p = 0.066) and the morning surge in mean arterial pressure (r = 0.48, p = 0.095) but these did not reach significance. There were no significant relationships between cardiac BRS and the morning surge. These findings indicate that the ability of the baroreflex to buffer increases in blood pressure via reflexive changes in MSNA may play a role in determining the magnitude of the MSBP.
Iodide accumulation provides kelp with an inorganic antioxidant impacting atmospheric chemistry

Brown algae of the Laminariales (kelps) are the strongest accumulators of iodine among living organisms. They represent a major pump in the global biogeochemical cycle of iodine and, in particular, the major source of iodocarbons in the coastal atmosphere. Nevertheless, the chemical state and biological significance of accumulated iodine have remained unknown to this date. Using x-ray absorption spectroscopy, we show that the accumulated form is iodide, which readily scavenges a variety of reactive oxygen species (ROS). We propose here that its biological role is that of an inorganic antioxidant, the first to be described in a living system. Upon oxidative stress, iodide is effluxed. On the thallus surface and in the apoplast, iodide detoxifies both aqueous oxidants and ozone, the latter resulting in the release of high levels of molecular iodine and the consequent formation of hygroscopic iodine oxides leading to particles, which are precursors to cloud condensation nuclei. In a complementary set of experiments using a heterologous system, iodide was found to effectively scavenge ROS in human blood cells.
Research-Informed Learning in the Psychology Curriculum: An Initial Evaluation

Research-informed teaching and learning have become an important area for development in psychology departments. There is an assumption that staff research can enhance the curriculum and the student experience. The methods of research and statistical awareness are also deemed important skills for a student in professional psychology to develop. This article reports an evaluation of the degree to which research informs staff teaching and the impact of research methods teaching on student employability. Undergraduate students and recent graduates were surveyed in a mixed qualitative and quantitative research design involving questionnaires, focus groups and a job analysis. A discrepancy was found between lecturers' and students' views of the extent to which staff's research informed their teaching. While lecturers regarded themselves as researchers as well as teachers, students regarded them as mainly teachers and ‘entertainers’. Where staff did refer to their own research to illustrate their teaching they were regarded as enthusiastic and authoritative. Staff-led projects in particular had a positive impact on both students and staff as they appeared to enhance group identity among the students involved and to improve students' understanding of research design. The focus on research, research methods, statistics and research ethics appears to have led some students to develop a critical attitude to events and information in the media and everyday life.
A magnetoencephalography study of functional brain connectivity in childhood, adolescence and adulthood

Functional brain networks are interconnected brain regions that flexibly coordinate their activity to support cognitive demands (Fair et al., 2009). Functional brain connectivity describes a statistical dependency between the activities recorded at spatially distinct brain regions (Friston, 2009). Changes in the pattern of connections and level of activation in functional brain networks are thought to occur across development (Taylor, Donner, & Pang, 2012) but the nature of these changes and their relationship to cognitive development have yet to be delineated clearly. This thesis seeks to deepen our understanding of the development of functional brain connectivity across the age range 9-25 years. We used magnetoencephalography in conjunction with canonical correlation analysis to explore functional connectivity via amplitude-amplitude envelope correlations in 110 datasets (39 working memory, 33 relevance modulation (attention processing) and 38 resting state). At the core of this thesis, we have presented novel findings that show non-linear functional connectivity changes across development, with an increase from childhood (age 9-12) to late adolescence (age 17-20) followed by a reduction into young adulthood (age 21-25), resembling an inverted-U-shaped trajectory at least in the females included in this study. Whilst there are subtle yet statistically significant differences in how the functional connectivity profile from 1-100 Hz is modulated by different factors, the overall pattern of functional connectivity development appears to be remarkably consistent across cognitive demands and networks. Critically, this work is the first example of such findings and suggests that functional brain networks supporting higher order cognitive function are not alone in undergoing functional development; sensory networks that reach structural maturity early on in life also undergo functional development from age 9 to 25.
A Method for Gene Disruption That Allows Repeated Use of URA3 Selection in the Construction of Multiply Disrupted Yeast Strains

In this paper, we describe a 3.8-kb molecular construct that we have used to disrupt yeast genes. The construct consists of a functional yeast URA3 gene flanked by 1.1-kb direct repeats of a bacterial sequence. It is straightforward to insert the 3.8-kb segment into a cloned target gene of interest and then introduce the resulting disruption into the yeast genome by integrative transformation. An appropriate DNA fragment containing the disruption plus flanking homology can be obtained by restriction enzyme digestion. After introducing such fragments into yeast by transformation, stable integrants can be isolated by selection for Ura+. The important feature of this construct that makes it especially useful is that recombination between the flanking direct repeats occurs at a high frequency (10-4) in vegetatively grown cultures. After excision, only one copy of the repeat sequence remains behind. Thus in the resulting strain, the Ura+ selection can be used again, either to disrupt a second gene in similar fashion or for another purpose.
A 12b 180MS/s 0.068mm2 pipelined-SAR ADC with merged-residue DAC for noise reduction

This paper presents a 12b 180 MS/s partial-interleaving Pipelined-SAR analog-to-digital converter (ADC). The 1st-stage is implemented with a 2b/cycle SAR ADC for high speed, where we propose a merged-residue-DAC technique to improve the noise performance. The capacitor pre-charging in conventional 2b/cycle operation wastes settling time and switching energy, while with this design approach the switching procedure is optimized to avoid the pre-charging for tri-level reference generation. The prototype ADC fabricated in 65nm CMOS achieves a SNDR of 63.8dB @DC input with 6mW power dissipation from a 1.2V supply, leading to a FoM @DC of 26.3 fJ/conv. -step.
Evidence for a Cluster-Based Structure of AIPdMn Single Quasicrystals.

For the first time quasicrystal surfaces produced by in situ cleavage in ultrahigh vacuum have been investigated by scanning tunneling microscopy. Twofold and fivefold surfaces of icosahedral AlPdMn single quasicrystals have been studied. The surfaces were found to be rough. Their structure is determined by cluster aggregates formed on the basis of an elementary cluster whose contrast behavior and diameter of about 1 nm point to the Mackay-type cluster. Crack propagation occurs along zones of lower strength between clusters. This supports the cluster approach to quasicrystal structure.