Miracle-dz/UniFAR-FTUs huggingface dataset:
Value-In-Context with Service Innovation in the Digital Age: A Service-Dominant Logic Perspective

The increasingly complex service context with the convergence of physical products, digitalization, and service offerings presents a major challenge for IS research on service innovation. This article addresses the resulting need for research on an adequate understanding of the perceived value of innovative digital services. It continues previous work that makes the first move in this regard—conceptualizing this value as the sum of direct value-in-context (S-D logic), and indirect and option value-in-context (both newly introduced). This article closes two research gaps. First, the option and indirect value-in-context components are clarified by developing propositions that link both to S-D logic’s main concepts of service innovation. Second, the value-in-context anatomy is empirically validated with two conjoint analyses. It can be shown that both newly introduced components of value-in-context indeed are decisive factors for customers’ perceptions of value with innovative digital services—implicating their conceptual separation.
Aqua[6-carboxylato-N′-(pyridin-2-ylmethylidene)pyridine-2-carbohydrazidato]copper(II) trihydrate

In the title compound, [Cu(C13H8N4O3)(H2O)]·3H2O, the complex molecule, except for the aqua ligand, is essentially planar [r.m.s. deviation = 0.034 (2) Å]. The coordination polyhedron of the Cu2+ cation is a square-pyramid, with the aqua ligand at the apex. The compound exhibits a three-dimensional structure, which is is stabilized by O—H⋯O and O—-H⋯N hydrogen bonds and π–π interactions [centroid–centroid distance = 2.987 (3) Å].
Changes in cell diameter during the division cycle of Escherichia coli

Extensive measurements of steady-state populations of several Escherichia coli strains have consistently indicated that cell diameter decreases with increasing cell length. This was observed both after electron microscopy of air-dried cells and after phase-contrast microscopy of living cells. The analysis was made by considering separately the unconstricted cells and three classes (slight, medium, and deep) of constricted cells in the population. During slow growth, cells with the average newborn length were up to 8% thicker than unconstricted cells twice as long. This decrease in diameter is less at higher growth rates. Despite the small changes and the large variation of the diameter in any particular length class, significant negative correlations between diameter and length were obtained. Cell diameter increases again at the end of the cell cycle as indicated by an increase of average diameter in the three consecutive classes of constriction.
Monocyte recruitment and neointimal hyperplasia in rabbits. Coupled inhibitory effects of heparin.

Among the many effects of heparin independent of its effects on coagulation are inhibition of vascular smooth muscle cell proliferation and regulation of leukocyte-blood vessel interactions. The potential link between these effects was examined in an animal model of vascular injury rich in inflammatory cells: the placement of endovascular metal stents in rabbit iliac arteries. Monocyte adhesion stimulated by early focal thrombus was maximal after 3 days, with infiltrating monocytes and intimal cell proliferation maximal after 7 days. Tissue monocyte number dictated cell proliferation at each time point (R2 = .92, P < .0001). Heparin reduced both early monocyte adhesion as well as monocyte infiltration within the neointima 7 and 14 days after stent placement. Reductions in adherent and tissue monocytes were commensurate with reductions in intimal cell proliferation and intimal thickening. At 14 days, heparin's inhibition of mononuclear cell adhesion was correlated with its suppression of intimal thickening (R2 = .82, P < .0001). Monocytes have been hypothesized to serve as markers, initiators, and promoters of arterial occlusive diseases. Heparin's ability to inhibit mononuclear cell adhesion and penetration and reduce neointimal size and cell proliferation after vascular injury may further implicate monocytes in the pathogenesis of neointimal hyperplasia after mechanical arterial injury.
Validity of the Active Straight Leg Raise Test for Measuring Disease Severity in Patients With Posterior Pelvic Pain After Pregnancy

Study Design. A cross-sectional analysis was performed with a group of women meeting strict criteria for posterior pelvic pain after pregnancy. The active straight leg raise test and common severity measurement scales of lumbopelvic pain were scored. Objective. To assess the validity of the active straight leg raise test as a disease severity scale for patients with posterior pelvic pain after pregnancy. Summary of Background Data. Various diagnostic tools are used to measure disease severity in patients with posterior pelvic pain after pregnancy, but simple tests with high reliability and validity still are needed. Methods. The investigation was performed with 200 women who had posterior pelvic pain after pregnancy. The validity of the active straight leg raise test as a severity scale was investigated by comparing the test score with the medical history, scores on self-reported disability scales, pain and tiredness, and pain provocation tests. The usefulness of the active straight leg raise test as a severity scale was compared with that of the Québec Back Pain Disability Scale. The influence of several demographic and anthropometric variables on the active straight leg raise score was investigated. Results. The active straight leg raise score ranged from 0 to 10 and correlated as expected with all severity scales. The correlation between the scores on the active straight leg raise test and the Québec Back Pain Disability Scale was 0.70. No association was found between the active straight leg raise score and age, parity, duration of the postpartum period, height, or weight. Conclusion. The active straight leg raise test can be recommended as a disease severity scale for patients with posterior pelvic pain after pregnancy.
Contrasting bacterial communities in two indigenous Chionochloa (Poaceae) grassland soils in New Zealand

The cultivation of grasslands can modify both bacterial community structure and impact on nutrient cycling as well as the productivity and diversity of plant communities. In this study, two pristine New Zealand grassland sites dominated by indigenous tall tussocks (Chionochloa pallens or C. teretifolia) were examined to investigate the extent and predictability of variation of the bacterial community. The contribution of free-living bacteria to biological nitrogen fixation is predicted to be ecologically significant in these soils; therefore, the diazotrophic community was also examined. The C. teretifolia site had N-poor and poorly-drained peaty soils, and the C. pallens had N-rich and well-drained fertile soils. These soils also differ in the proportion of organic carbon (C), Olsen phosphorus (P) and soil pH. The nutrient-rich soils showed increased relative abundances of some copiotrophic bacterial taxa (including members of the Proteobacteria, Bacteroidetes and Firmicutes phyla). Other copiotrophs, Actinobacteria and the oliogotrophic Acidobacteria showed increased relative abundance in nutrient-poor soils. Greater diversity based on 16S rRNA gene sequences and the Tax4Fun prediction of enhanced spore formation associated with nutrient-rich soils could indicate increased resilience of the bacterial community. The two sites had distinct diazotrophic communities with higher diversity in C. teretifolia soils that had less available nitrate and ammonium, potentially indicating increased resilience of the diazotroph community at this site. The C. teretifolia soils had more 16S rRNA gene and nifH copies per g soil than the nutrient rich site. However, the proportion of the bacterial community that was diazotrophic was similar in the two soils. We suggest that edaphic and vegetation factors are contributing to major differences in the composition and diversity of total bacterial and diazotrophic communities at these sites. We predict the differences in the communities at the two sites will result in different responses to environmental change.
Acute effects of tidal volume strategy on hemodynamics, fluid balance, and sedation in acute lung injury*

Objective:To examine the effects of mechanical ventilation with a tidal volume of 6 mL/kg compared with 12 mL/kg predicted body weight on hemodynamics, vasopressor use, fluid balance, diuretics, sedation, and neuromuscular blockade within 48 hrs in patients with acute lung injury and acute respiratory distress syndrome. Design:Retrospective analysis of a previously conducted randomized, clinical trial. Setting:Two adult intensive care units at a tertiary university medical center and a large county hospital. Patients:One hundred eleven patients who were enrolled in the National Institutes of Health ARDS Network trial at the University of California, San Francisco. Interventions:None. Measurements and Main Results:Compared with 12 mL/kg predicted body weight, treatment with a tidal volume of 6 mL/kg predicted body weight had no adverse effects on hemodynamics. There were also no differences in the need for supportive therapies, including vasopressors, intravenous fluids, or diuretics. In addition, there were no differences in body weight, urine output, and fluid balance. Finally, there was no difference in the need for sedation or neuromuscular blockade between the two tidal volume protocols. Conclusions:When compared with ventilation with 12 mL/kg predicted body weight, patients treated with the lung-protective 6 mL/kg predicted body weight tidal volume protocol had no difference in their supportive care requirements. Therefore, concerns regarding potential adverse effects of this protocol should not preclude its use in patients with acute lung injury or the acute respiratory distress syndrome.
Household Life Cycle Protection: Human Capital Versus Life Insurance

This paper investigates whether households substitute the wife's human capital (education) for "pure'" insurance on the husband. In particular, a highly educated wife possesses valuable marketable skills which may fulfill the primary roles of insurance. The results suggest that households with a more educated wife, ceteris paribus, have a lower likelihood of purchasing term insurance on the husband. They also suggest that uncertainty, household wealth, current household income, existing coverage, current non-term insurance purchases, household characteristics, and the decision-making environment are important determinants of a household's insurance purchasing behavior.
A pilot trial of doxorubicin containing phosphatidyldiglycerol based thermosensitive liposomes in spontaneous feline soft tissue sarcoma

Abstract Purpose: Doxorubicin (DOX)-loaded phosphatidyldiglycerol-based thermosensitive liposomes (DPPG2-TSL-DOX) combined with local hyperthermia (HT) was evaluated in cats with locally advanced spontaneous fibrosarcomas (soft tissue sarcoma [STS]). The study was designed to evaluate the safety and pharmacokinetic profile of the drug. Results from four dose-levels are reported. Methods: Eleven client-owned cats with advanced STS were enrolled. Five cats received escalating doses of 0.1–0.4 mg/kg DOX (group I), three received 0.4 mg/kg constantly (group II) and three 0.6 mg/kg (group III) IV over 15 min. HT with a target temperature of 41.5 °C was started 15 min before drug application and continued for a total of 60 min. Six HT treatments were applied every other week using a radiofrequency applicator. Tumour growth was monitored by magnetic resonance imaging (MRI) and for dose level III also with 18F-FDG PET. Results: Treatment was generally well tolerated and reasons for premature study termination in four cats were not associated with drug-induced toxicity. No DPPG2-TSL-DOX based hypersensitivity reaction was observed. One cat showed simultaneous partial response (PR) in MRI and positron emission tomography (PET) whereas one cat showed stable disease in MRI and PR in PET (both cats in dose level III). Pharmacokinetic measurements demonstrated DOX release triggered by HT. Conclusion: DPPG2-TSL-DOX + HT is a promising treatment option for advanced feline STS by means of targeted drug delivery. As MTD was not reached further investigation is warranted to determine if higher doses would result in even better tumour responses.
The Causal Impact of Attending High Tech High’s High Schools on Postsecondary Enrollment

In recent years, a small but growing number of empirical studies have examined the causal impact of attending charter schools on academic achievement (Betts and Tang, 2011). In assessing achievement, researchers have focused on short-term, educational outcomes such as student results on state-mandated exams. To date, little research has examined how charter schools impact educational outcomes over the mediumand longterm. I examine the causal impact of attending High Tech High (HTH), a wellestablished charter school network of 12 schools based in San Diego, California, on postsecondary enrollment. I find that attending HTH in high school increases the likelihood of enrollment in a four-year college by 10.9 percentage points and decreases the likelihood of enrollment in a two-year college by 11.2 percentage points. This observed shift suggests that HTH effectively prepares its students to apply, gain admission, and/or ultimately attend four-year colleges over two-year colleges. My study also speaks to the question of who applies to charter schools. I find that the postsecondary enrollment rate among those who apply but are not admitted to HTH is roughly 12 percentage points higher than the overall rate among graduates of high schools managed by the San Diego Unified School District (SDUSD). This observation suggests that the composition of students and families who apply to HTH in high school
Exciton-exciton and exciton-phonon interactions in an interfacial GaAs quantum dot ensemble

G. Moody,1,2 M. E. Siemens,1,* A. D. Bristow,1,† X. Dai,1,‡ D. Karaiskaj,1,§ A. S. Bracker,3 D. Gammon,3 and S. T. Cundiff1,2,‖ 1JILA, University of Colorado & National Institute of Standards and Technology, Boulder, Colorado 80309-0440, USA 2Department of Physics, University of Colorado, Boulder, Colorado 80309-0390, USA 3Naval Research Laboratory, Washington, DC 20375, USA (Received 2 August 2010; revised manuscript received 16 December 2010; published 23 March 2011)
A study of supervised intrinsic spectral analysis for TIMIT phone classification

Intrinsic Spectral Analysis (ISA) has been formulated within a manifold learning setting allowing natural extensions to out-of-sample data together with feature reduction in a learning framework. In this paper, we propose two approaches to improve the performance of supervised ISA, and then we examine the effect of applying Linear Discriminant technique in the intrinsic subspace compared with the extrinsic one. In the interest of reducing complexity, we propose a preprocessing operation to find a small subset of data points being well representative of the manifold structure; this is accomplished by maximizing the quadratic Renyi entropy. Furthermore, we use class based graphs which not only simplify our problem but also can be helpful in a classification task. Experimental results for phone classification task on TIMIT dataset showed that ISA features improve the performance compared with traditional features, and supervised discriminant techniques outperform in the ISA subspace compared to conventional feature spaces.
Phoneme-based English-Amharic Statistical Machine Translation

This research considers the application of Statistical method to automatic Machine Translation (MT) from English to Amharic. The research focuses on improving the translation quality by applying phonemic transcription on the target side, which is Amharic. Accordingly, the BLEU score results for the phoneme-based EASMT system is 37.53% a gain of 2.21 BLEU point from another baseline phrase-based EASMT with a BLEU score result of 35.32%. This clearly shows that phoneme-based translation outperforms the baseline system.
β-Masking MMSE speech enhancement for speech recognition

Speech recognition performance deteriorates drastically when they are deployed in practical situation where the speech is corrupted by additive noise. One way to improve the robustness of the speech recognition system is to enhance the speech prior to its recognition. This paper focuses on developing a masking-based ß-order minimum mean square error (ß-masking MMSE) speech enhancement for speech recognition under noise condition. Addressing the artifacts introduced by enhancement algorithm and the remaining noise after denoising, we modified the estimation algorithm of spectral parameters for the ß-masking MMSE by controlling the power of processing noise, strengthening the weak signal processing, oversuppressing the residual noise and reestimating a priori SNR. The evaluation shows the proposed enhancement scheme is significantly effective to improve the performance of state-of-the-art speech recognition.
The Impact of Green Innovation on Employment Growth in Europe

This paper studies the impact of environmental innovation on employment growth using firmlevel data for 16 European countries and the period 2006-2008. It extends the model by Harrison et al (2008) in order to distinguish between employment effects of environmental and non-environmental product as well as process innovation. By looking at country and sector level differences, it also generates new insights into the heterogeneity of the environmental innovation-employment growth link along different dimensions. The results demonstrate that both environmental and non-environmental product innovations are conducive to employment growth in European firms. We estimate a gross employment effect of product innovation for both types of product innovators that is very similar in nearly all countries and sectors. That is, in most cases a one-percent increase in the sales due to new products for environmental product innovators also increases gross employment by one percent. This implies that there is no evidence that environmentally-friendly new products are produced with higher or lower efficiency than old products. Yet, we observe differences in the contribution of environmental and non-environmental product innovation to employment growth across countries or sectors that are the result of differences in the average innovation engagement and innovation success across countries or sectors. The absolute contribution to employment growth is positive for both types of new products. However, we find mixed evidence for the relative importance. In manufacturing the contribution of environmental product innovators was larger than that of non-environmental product innovators in half of the countries. In services, however, non-environmental product innovators matters more for growth in the vast majority of countries. In contrast, environmental and non-environmental process innovation plays only a little role for employment growth.
Probiotic yogurt in the elderly with intestinal bacterial overgrowth: endotoxaemia and innate immune functions

A study was conducted in healthy elderly living independently in senior housing to assess the impact of a probiotic yoghurt supplement on small intestinal bacterial overgrowth. Twenty-three participants with positive and thirteen participants with negative hydrogen breath test were studied before and after a period of 4 weeks of probiotic yoghurt administration. Intestinal permeability, plasma endotoxin levels, phagocytic activity of leucocytes, cytokine production by monocytes and free radical response of neutrophils were determined. Intestinal permeability was similar for the two groups and was unaffected by probiotic treatment. Both plasma endotoxin levels and the basal phagocytic activity of leucocytes decreased after yoghurt intake in the two groups. Exposure of monocytes and neutrophils ex vivo led to an increased cytokine response and free radical response, respectively. The normalisation of the various cytokine responses was more apparent in the group with positive breath test. In addition, the plasma levels of lipoplysaccharide binding protein and soluble CD14, lipoplysaccharide pattern recognition receptors and surrogate markers of lipoplysaccharide permeability were diminished by the end of the study. In conclusion, probiotic administration in the elderly normalises the response to endotoxin, and modulates activation markers in blood phagocytes, and therefore may help reduce low-grade chronic inflammation.
Anal Condyloma Treatment and Recurrence in HIV-negative Men Who Have Sex With Men

BACKGROUND: Men who have sex with men have increased prevalence of both human papillomavirus and anogenital condyloma. OBJECTIVE: Risk factors for multiple treatment and recurrence of anal condyloma were examined. DESIGN: This is a retrospective study of HIV-negative men who have sex with men who were treated for anal condyloma. SETTINGS: This study was conducted in a private surgical practice. PATIENTS: The patients were HIV-negative men who have sex with men, aged 18 years or older. INTERVENTION(S): Ablation with electrocautery or CO2 laser was performed, as well as excision and topical imiquimod condyloma treatment adjuvant. MAIN OUTCOME MEASURES: Primary clearance, defined as 4 months of condyloma-free survival posttreatment, and recurrence, defined as any anal condyloma diagnosis after primary clearance. RESULTS: Of 231 participants, 207 achieved primary clearance (median age, 32.0 years) and were followed (median, 18.2 months) after primary treatment. Most had intra-anal and perianal condyloma (56%), were treated with electrocautery ablation (79.2%), and required 1 treatment (range, 1–6) for clearance. There were 57 recurrences (median, 12 months). One-third each had minimal, moderate, or extensive disease. Forty-six percent of patients received imiquimod posttreatment adjuvant. High-grade dysplasia was found in 31% at presentation and 43% during follow-up. Factors associated with requiring multiple treatments for clearance were participants having moderate disease (adjusted odds ratio, 6.0 (1.7–21.4)) and receiving imiquimod adjuvant (adjusted odds ratio, 4.7 (2.0–10.6)). No single factor predicted recurrence, but those with moderate disease experienced recurrences significantly sooner (median, 25 months of follow-up). LIMITATIONS: This was a retrospective chart review, it was limited to a single practice, and it excluded those who did not achieve primary clearance. CONCLUSIONS: Most men who have sex with men have intra-anal and perianal condyloma and concomitant high-grade dysplasia is common. Most achieved clearance with 1 treatment. Having both intra-anal and perianal condyloma, increased severity of disease, and imiquimod adjuvant were significant predictors of requiring multiple treatments for clearance. No identified risk factors proved a significant predictor of recurrence.
Dynamic reputation-based trust computation in private networks

The use of collaborative networks services in general, and web based social networks (WBSN) services in particular, is today increasing and, therefore, the protection of the resources shared by network participants is becoming a crucial need. In a collaborative network, one of the main parameters on which access control relies is represented by trust and reputation, since access to a resource may or may not be granted on the basis of the trust/reputation of the requesting node. Therefore, the calculation of the trust of the nodes becomes a very important issue, mainly in business to business (BtoB) social networks, where trustworthy nodes can increase their benefits taking profit of their good reputation in the network. In order to address this point, in this paper we propose a mechanism to dynamically compute nodes trust, based on their past behavior. The key characteristic of our proposal is that trust is computed in a private way. This is obtained by anonymizing the local log files storing information about nodes actions.