Miracle-dz/UniFAR-FTUs huggingface dataset:
Certificateless public key encryption with keyword search

Public Key Encryption with Keyword Search (PEKS), an indispensable part of searchable encryption, is stock-in-trade for both protecting data and providing operability of encrypted data. So far most of PEKS schemes have been established on Identity-Based Cryptography (IBC) with key escrow problem inherently. Such problem severely restricts the promotion of IBC-based Public Key Infrastructure including PEKS component. Hence, Certifcateless Public Key Cryptography (CLPKC) is efficient to remove such problem. CLPKC is introduced into PEKS, and a general model of Certifcateless PEKS (CLPEKS) is formalized. In addition, a practical CLPEKS scheme is constructed with security and efficiency analyses. The proposal is secure channel free, and semantically secure against adaptive chosen keyword attack and keyword guessing attack. To illustrate the superiority, massive experiments are conducted on Enron Email dataset which is famous in information retrieval field. Compared with existed constructions, CLPEKS improves the efficiency in theory and removes the key escrow problem.
The ANGULATA7 gene encodes a DnaJ‐like zinc finger‐domain protein involved in chloroplast function and leaf development in Arabidopsis

The characterization of mutants with altered leaf shape and pigmentation has previously allowed the identification of nuclear genes that encode plastid-localized proteins that perform essential functions in leaf growth and development. A large-scale screen previously allowed us to isolate ethyl methanesulfonate-induced mutants with small rosettes and pale green leaves with prominent marginal teeth, which were assigned to a phenotypic class that we dubbed Angulata. The molecular characterization of the 12 genes assigned to this phenotypic class should help us to advance our understanding of the still poorly understood relationship between chloroplast biogenesis and leaf morphogenesis. In this article, we report the phenotypic and molecular characterization of the angulata7-1 (anu7-1) mutant of Arabidopsis thaliana, which we found to be a hypomorphic allele of the EMB2737 gene, which was previously known only for its embryonic-lethal mutations. ANU7 encodes a plant-specific protein that contains a domain similar to the central cysteine-rich domain of DnaJ proteins. The observed genetic interaction of anu7-1 with a loss-of-function allele of GENOMES UNCOUPLED1 suggests that the anu7-1 mutation triggers a retrograde signal that leads to changes in the expression of many genes that normally function in the chloroplasts. Many such genes are expressed at higher levels in anu7-1 rosettes, with a significant overrepresentation of those required for the expression of plastid genome genes. Like in other mutants with altered expression of plastid-encoded genes, we found that anu7-1 exhibits defects in the arrangement of thylakoidal membranes, which appear locally unappressed.
Requirement of the Pr55gag precursor for incorporation of the Vpr product into human immunodeficiency virus type 1 viral particles

The human immunodeficiency virus type 1 (HIV-1) particles consists of two molecules of genomic RNA as well as molecules originating from gag, pol, and env products, all synthesized as precursor proteins. The 96-amino-acid Vpr protein, the only virion-associated HIV-1 regulatory protein, is not part of the virus polyprotein precursors, and its incorporation into virus particles must occur by way of an interaction with a component normally found in virions. To investigate the mechanism of incorporation of Vpr into the HIV-1 virion, Vpr- proviral DNA constructs harboring mutations or deletions in specific virion-associated gene products were cotransfected with Vpr expressor plasmids in COS cells. Virus released from the transfected cells was tested for the presence of Vpr by immunoprecipitation with Vpr-specific antibodies. The results of these experiments show that Vpr is trans-incorporated into virions but at a lower efficiency than when Vpr is expressed from a proviral construct. The minimal viral genetic information necessary for Vpr incorporation was a deleted provirus encoding only the pr55gag polyprotein precursor. Incorporation of Vpr requires the expression but not the processing of gag products and is independent of pol and env expression. Direct interaction of Vpr with the Pr55gag precursor protein was demonstrated by coprecipitation experiments with gag product-specific antibodies. Overall, these results indicate that HIV-1 Vpr is incorporated into the nascent virion through an interaction with the Gag precursor polyprotein and demonstrate a novel mechanism by which viral protein can be incorporated into virus particles.
Exercise and dietary change after diagnosis and cancer‐related symptoms in long‐term survivors of breast cancer: CALGB 79804

Objective: Improving diet and exercise can reduce survivors' risk of cancer‐related fatigue, poor physical functioning, and potential recurrence. A cancer diagnosis can represent a ‘teachable moment’, leading survivors to make positive changes in diet and exercise behaviors; however, little is known about how often this occurs or about factors that enhance or limit survivors' ability to make these changes. This cross‐sectional descriptive study investigated both the prevalence and clustering of self‐reported changes in diet and exercise and how these changes related to ongoing cancer‐related symptoms, social support, and stressful life events among long‐term breast cancer survivors.
Radiotherapy and gemcitabine-docetaxel chemotherapy in children and adolescents with unresectable recurrent or refractory osteosarcoma.

OBJECTIVE Few reports have described the treatment outcome of osteosarcoma using radiotherapy. We evaluated the efficacy of radiotherapy and gemcitabine and docetaxel chemotherapy for patients with unresectable recurrent or refractory osteosarcoma. METHODS Data from six patients (five male, one female) who received radiotherapy and gemcitabine and docetaxel chemotherapy at the Korea Cancer Center Hospital were retrospectively reviewed. Tumor response was evaluated according to metabolic changes using (18)F-fluorodeoxy-D-glucose-positron emission tomography. RESULTS The median age of the patients was 15.0 years (range, 14.0-15.8 years). Two patients had single bone lesions, and four had multiple metastatic bone lesions. Patients received a median 3.5 courses of gemcitabine and docetaxel chemotherapy (range, 2-6 courses). The median dose of radiotherapy was 50.0 Gy (range, 46-84 Gy). There were two complete metabolic responses and one partial metabolic response. The objective response rate was 50.0% (3/6). Responses were maintained for 4.6, 6.1 and 13.7 months, respectively. Patients were followed up for a median of 5.8 months (range, 2.7-84.6 months), and the median progression-free survival after this treatment was 3.6 months (range, 1.1-13.7 months). At the time of analysis, two patients were alive, one was lost to follow-up and three had died. CONCLUSION Radiotherapy with gemcitabine and docetaxel chemotherapy showed some improvement in cases of refractory tumors or multiple bone metastases. Further studies are needed to investigate the efficacy of newer radiotherapy modalities, as well as to identify new radiosensitizing chemotherapy regimens.
Single-camera dedicated television control system using gesture drawing

As gesture recognition technology has improved, it has been applied to various consumer appliances to provide natural interfaces. Television is a representative system for this kind of interface because of its complex requirements for various functions. Icon-based interfaces are the general method used. However, according to the performed survey, various functions were not required for watching TV. This work found most viewers mainly tend to use some specific functions such as channel or volume. These functions should be controlled easily and quickly since they are frequently used. However, the iconbased interface has difficulty fulfilling this requirement since it is affected by Fitts' law. Hence, this paper proposes a gesturebased method for easy and quick control. User hand gestures are recognized by capturing the motion path when the user draws different symbols in the air. These gestures are used to interact with the TV. It is implemented using a single-camera dedicated hardware system. This system is based on a real time parallel processing structure. The analysis shows that subjects enjoy this TV control system.
Continuum of depressive and manic mixed states in patients with bipolar disorder: quantitative measurement and clinical features

Bipolar mixed states combine depressive and manic features, presenting diagnostic and treatment challenges and reflecting a severe form of the illness. DSM-IV criteria for a mixed state require combined depressive and manic syndromes, but a range of mixed states has been described clinically. A unified definition of mixed states would be valuable in understanding their diagnosis, mechanism and treatment implications. We investigated the manner in which depressive and manic features combine to produce a continuum of mixed states. In 88 subjects with bipolar disorder (DSM-IV), we evaluated symptoms and clinical characteristics, and compared depression-based, mania-based, and other published definitions of mixed states. We developed an index of the extent to which symptoms were mixed (Mixed State Index, MSI) and characterized its relationship to clinical state. Predominately manic and depressive mixed states using criteria from recent literature, as well as Kraepelinian mixed states, had similar symptoms and MSI scores. Anxiety correlated significantly with depression scores in manic subjects and with mania scores in depressed subjects. Discriminant function analysis associated mixed states with symptoms of hyperactivity and negative cognitions, but not subjective depressive or elevated mood. High MSI scores were associated with severe course of illness. For depressive or manic episodes, characteristics of mixed states emerged with two symptoms of the opposite polarity. This was a cross-sectional study. Mixed states appear to be a continuum. An index of the degree to which depressive and manic symptoms combine appears useful in identifying and characterizing mixed states. We propose a depressive or manic episode with three or more symptoms of the opposite polarity as a parsimonious definition of a mixed state.
Fractional order calculus-based filters for biomedical signal processing

The goal of this paper is to give a review of some applications of fractional order calculus to biomedical signal processing with emphasis on the ability of this mathematical tool to remove noise, enhance useful information, and generate fractal signals. Three types of digital filters are considered, namely, lowpass differentiation filter, smoothing filter, and 1/fβ-noise generation filter. The filter impulse responses are function of the fractional order and the sampling period only, and thus can be computed easily. Application examples are presented for illustrations.
Is there a conflict between minimizing effort and energy expenditure with increasing velocities of muscle contraction in humans?

1 The present study examined the possibility that minimizing effort conflicts with minimizing energy expenditure at different velocities of muscle contraction during cycling. 2 Six normal subjects underwent incremental exercise on an electrically stabilized cycle ergometer. Power output increased by 45 W every 3 min to exhaustion at pedalling frequencies of 40, 60, 80 and 100 r.p.m. on separate days. Energy expenditure (oxygen uptake), leg effort and dyspnoea (Borg 0‐10 scale) were measured in parallel at the end of each minute. 3 All six subjects completed 10 min of exercise achieving 180 W for all four pedalling frequencies. Two‐way analysis of variance indicated that oxygen uptake (P < 0.0001), leg effort (P < 0.0001) and dyspnoea (P < 0.0001) increased with duration of exercise and power output; oxygen uptake (P < 0.0001) and leg effort (P < 0.05) were significantly different between pedalling frequencies; the interactions were not significant. Oxygen uptake was minimal at 60 r.p.m. , and increased at both higher and lower pedalling frequencies. Both leg effort and dyspnoea were minimal at 80 r.p.m. ; leg effort intensified at higher and lower pedalling frequencies; and dyspnoea was most intense at 100 r.p.m. 4 There was a conflict between minimization of energy expenditure and leg effort at power outputs less than 180 W. Minimizing effort occurred at the expense of an increase in energy expenditure.
Automatic Extraction of Urban Vegetation Structures from High Resolution Imagery and Digital Elevation Model

This paper presents a method for automatic extraction and characterisation of vegetation structures (such as trees, shrubs, hedges or lawns) in high density urban areas. We present a hierarchical strategy to extract, analyze and delineate vegetation areas according to their height. Spectral indices are used to detect urban vegetation areas. We differentiate lawns from treed areas by computing a texture operator on the digital elevation model (DEM) corresponding to the vegetation areas previously detected. A robust region growing method based on the DEM is developed for an accurate delineation of tree crowns. We evaluate the accuracy of the tree crown delineation results to a reference manual delineation. Results obtained are discussed and the influential factors are put forward.
Psychometric character of purpose in life test-short form in college students

Objective To research the psychometric properties and usability of the Purpose in Life Test-Short Form(PIL-SF) for Chinese University students. Methods 997 college students were measured by Purpose in Life (PIL), Meaningful Life Measure (MLM) and the Satisfaction with Life Scale (SWLS), and 120 college students were twice measured by the same questionnaire after four weeks. Results The item discrimination index were all above 0.7(r=0.753~0.838, P<0.01). The internal consistency reliability of PIL-SF was 0.811, the split-half reliability was 0.774 and the test-retest reliability was 0.786. The criterion correlations of PIL-SF with PIL, MLM and SWLS was 0.83, 0.67 and 0.46 respectively (P<0.01). The PIL-SF average scores of these students was 5.18±1.09. Most of the college students' meaning of life were at a relatively higher level. There were 10.9% of students lack goals and poor meaning of life, 23.5% of them do not have clear purpose, relatively lower meaning of life, 37.5% of them had relatively higher meaning of life and 28.1% of them hold explicit purpose. Conclusion The reliability and validity of PIL-SF are favorable, and it is a useful tool to be used in the mental health screening and evaluation the people’s meaning in life quickly. Key words: Meaning in life; Purpose in life; Purpose in life test; Reliability; Validity
High-Resistance Faults on Two Terminal Parallel Transmission Line: Analysis, Simulation Studies, and an Adaptive Distance Relaying Scheme

Performance of conventional nonpilot distance relay is affected by ground fault resistance, prefault system conditions, mutual effects of parallel lines and shunt capacitance influences. The work presented in this paper addresses the problems encountered by conventional non pilot distance relay when protecting two terminal parallel transmission lines. One of the key points of this paper is the detailed analysis of the apparent impedance as seen from the relaying point taking into account the effects of transmission line parameter uncertainties, mutual effects of parallel lines for simple and more complex configuration, shunt capacitance influences and variations in the system external to the protected line. Based on extensive computer simulations of the infeed/outfeed, fault resistance, mutual coupling and shunt capacitance effects on the relay characteristics, an adaptive digital distance relaying scheme is proposed using radial basis function neural network which provides more efficient approach for training, computation, adaptation and tripping than the conventional feed forward network using back propagation algorithm. In addition, the proposed adaptive scheme improves the performance of distance relay for double-circuit lines using modified compensation factor. Moreover, the scheme does not require separate communication channel for data transmission. The results of computer simulation show the improvement of sensitivity and selectivity of the relay
Low cost fault tolerant techniques for nano/pico-satellite applications

Space is a hazardous environment for electronic equipment due to various high energy particles, also referred to as radiation, which adversely affect electronic components. The most notable of these radiation effects are single event latchups and single event upsets. In large and expensive satellites the use of radiation hardened components and redundancy mitigates the effects of radiation on the satellite. These techniques are not feasible on small satellites, especially in the nano to pico range, due to their limited power, size and financial budgets. However, by using fault tolerant design techniques (watchdogs, anti-latchup circuitry, error correction code) and implementing a robust bootloader for in-flight reprogramming, it is possible to achieve an acceptable fault tolerance level for short duration missions within low earth orbit with minimal overhead on the design. These low cost mitigation techniques have been implemented on a CubeSat onboard computer, to be used in the upcoming ZACube2 mission. The evaluation and implementation of these techniques and their impact on the onboard computer in terms of power, size and cost are discussed in this paper.
Curative treatment of atrial fibrillation with intraoperative radiofrequency ablation: short-term and midterm results.

OBJECTIVE This report describes the early and midterm results after intraoperative radiofrequency ablation of atrial fibrillation for patients with isolated chronic atrial fibrillation or atrial fibrillation in combination with additional valvular and nonvalvular cardiac diseases. METHODS From August 1998 to March 2001, a total of 234 patients with chronic atrial fibrillation underwent isolated intraoperative radiofrequency ablation alone (n = 74, 31.6%) or in combination with other cardiac procedures, such as mitral valve reconstruction (n = 57, 24.4%), mitral valve replacement (n = 38, 16.2%), aortic valve replacement (n = 11, 5.1%), coronary artery bypass grafting (n = 8, 5.0%), or a combination of the last with other cardiac procedures (n = 46, 19.7%). In all cases anatomic reentrant circuits confined within the left atrium were eliminated by placing contiguous lesion lines involving the mitral anulus and the orifices of the pulmonary veins through the use of radiofrequency energy application (exposure time, 20 seconds). A median sternotomy was used in 101 cases (43.2%), and video assistance through a right lateral minithoracotomy was used in 133 cases (56.8%). RESULTS A total of 188 patients (83.9%) were discharged in sinus rhythm, 17 patients (7.6%) had atrial fibrillation, and 19 patients (8.5%) had atypical flutter. Pacemakers were implanted in 23 patients (9.8%). There were 10 in-hospital deaths (4.2%), and 30-day mortality was 5 patients (2.1%). In 3 cases (1.3%) an atrioesophageal fistula developed, necessitating surgical repair. Six months' follow-up was complete for 122 (61.0%) of 200 patients, with 99 patients still in stable sinus rhythm (81.1%, 95% confidence interval 73.1%-89.9%). Twelve months' follow-up was complete for 80 (90.9%) of 88 patients, with 58 patients still in sinus rhythm (72.5%, 95% confidence interval 61.3%-83.2%). CONCLUSIONS Intraoperative radiofrequency ablation is a curative procedure for chronic atrial fibrillation. It is technically less challenging than the maze procedure and can be applied through a minimally invasive approach. Protection of the esophagus seems mandatory to avoid the deleterious complication of a left atrioesophageal fistula, such as was observed in 3 cases.
Carbon Isotope Fractionation of 11 Acetogenic Strains Grown on H2 and CO2

ABSTRACT Acetogenic bacteria are able to grow autotrophically on hydrogen and carbon dioxide by using the acetyl coenzyme A (acetyl-CoA) pathway. Acetate is the end product of this reaction. In contrast to the fermentative route of acetate production, which shows almost no fractionation of carbon isotopes, the acetyl-CoA pathway has been reported to exhibit a preference for light carbon. In Acetobacterium woodii the isotope fractionation factor (ε) for 13C and 12C has previously been reported to be ε = −58.6‰. To investigate whether such a strong fractionation is a general feature of acetogenic bacteria, we measured the stable carbon isotope fractionation factor of 10 acetogenic strains grown on H2 and CO2. The average fractionation factor was εTIC = −57.2‰ for utilization of total inorganic carbon and εacetate = −54.6‰ for the production of acetate. The strongest fractionation was found for Sporomusa sphaeroides (εTIC = −68.3‰), the lowest fractionation for Morella thermoacetica (εTIC = −38.2‰). To investigate the reproducibility of our measurements, we determined the fractionation factor of 21 biological replicates of Thermoanaerobacter kivui. In general, our study confirmed the strong fractionation of stable carbon during chemolithotrophic acetate formation in acetogenic bacteria. However, the specific characteristics of the bacterial strain, as well as the cultural conditions, may have a moderate influence on the overall fractionation.
Susceptibility of Actinobacillus actinomycetemcomitans to six antibiotics decreases as biofilm matures.

OBJECTIVES Actinobacillus actinomycetemcomitans is a major causative agent of chronic and aggressive periodontitis. Freshly isolated strains of A. actinomycetemcomitans display rough-type colonies and initiate biofilm formation on glass surfaces. The purpose of this study was to determine the antibiotic susceptibility of A. actinomycetemcomitans biofilm during different phases of maturation. METHODS Using 96-well microtitre plates, we determined the antibiotic susceptibility of rough-type strain 310a to concentrations from 0.1 to 10 mg/L each of erythromycin, ofloxacin, ampicillin, cefalexin, tetracycline and minocycline during biofilm formation. Antibiotics were added at the start of the culture (early phase) and after 24 h of cultivation (mature phase). RESULTS Adding 10 mg/L of ampicillin, 10 mg/L of cefalexin, 0.1 or 1 mg/L of tetracycline, or 0.1 mg/L of minocycline significantly inhibited 310a biofilm formation in the early phase, but not in the mature phase. Although adding 10 mg/L of erythromycin, tetracycline or minocycline reduced biofilm development in the early phase, it enhanced 310a biofilm development in the mature phase. Ofloxacin exerted a strong inhibitory effect in both the early and mature phases of biofilm formation throughout all experiments. CONCLUSIONS The present study demonstrated that the susceptibility of A. actinomycetemcomitans to many antibiotics decreased after biofilm maturation.