Miracle-dz/UniFAR-FTUs huggingface dataset:
Purpose in Life and Personal Growth: Predictors of Quality of Life in Mexican Elders

Pursue goals and dreams throughout life are important to maintain an active life and enjoy it, which turns out to be a mechanism where people adapt to the challenges of the age, also if they are able to use their resources to continue growing as people, all should contribute to a better quality of life. Therefore the aim is to test the predictive value of subjective well-being, their dimensions: purpose in life and personal growth on quality of life of older adults from different entities of Mexico. For that, 582 elderly (mean age = 70.3, SD = 7.5) were individually interviewed, also they answered with their consent informed, the questionnaire Quality of Life (QoL) (WHOQOL-OLD) and the Ryff’s Scale of Subjective Well-Being (SW) with two of its dimensions: Purpose in Life (PiL) and Personal Growth (PG). The results show statistically significant correlations between QoL and PiL (r = .565, p < .0001), QoL and PG (r = .442, p < .0001), and QoL and SW (r = .633, p < .0001). Also the resulting linear regression model with significant coefficients is: PiL (β = 0.134, p < .038), PG (β = ? 0.138, p < .025) and SW (β = 0.632, p < .0001), value F(3,423) = 99.28, p < . 0001 and coefficient R2 = . 413. It is concluded that the purpose in life, personal growth and well-being are predicting a better quality of life of older adults.
INVENTORY, TAXONOMY AND ASSESSMENT OF METHODS FOR INTERNATIONAL MARKET SELECTION

This article assesses the state‐of‐the‐art on the subject of international market selection based on a comprehensive review and synthesis of the literature. It provides an inventory, taxonomy and brief review of the normative quantitative models that have been proposed in the literature, and compares them to current business practices in selecting foreign markets. This comparison reveals a theory‐practice gap that is discussed in the context of the methodological and conceptual weaknesses of the models. Suggestions for future research are made.
The putative DNA translocase SpoIIIE is required for sporulation of the symmetrically dividing coccal species Sporosarcina ureae

The spoIIIE gene of Sporosarcina ureae encodes a 780‐residue protein, showing 58% identity to the SpoIIIE protein of Bacillus subtilis, which is thought to be a DNA translocase. Expression of the S. ureae spoIIIE gene is able to restore sporulation in a B. subtilis spoIIIE mutant. Inactivation of the S. ureae spoIIIE gene blocks sporulation of S. ureae at stage III. Within the limits of detection, the sporulation division in S. ureae shows the same symmetry, or near symmetry, as the vegetative division (in contrast to the highly asymmetric location of the sporulation division for B. subtilis), and so it is inferred that SpoIIIE facilitates chromosome partitioning during sporulation, even when the division is not grossly asymmetric. It is suggested that chromosome partitioning lags behind division during sporulation but not during vegetative growth.
Distance Educations for Computers Undeveloped Country Like in Nepal: Prospects and Challenges

Broadly, the beginning of Distance Education for Computers dates back to 18th Century due to the phenomenal advancement and innovation in transportation and communication heralded by industrial revolution. DEC as alternative model of education started when technology made it feasible to separate teacher and learner from a fixed place, at a fixed time, to meet a fixed person, in order to be trained. Started with correspondence mode, DEC is now agreed to have undergone notably four other stages namely multimedia mode, tele-learning model, flexible learning model and interactive flexible learning model. The proliferation suffices to prove why DEC has been so widely accepted in the western hemisphere and why European countries have established and recognized this method through EDEN.
MACA-a New Channel Access Method for Packet Radio

n a The existing Carrier Sense Multiple Access (CSMA) method widely used i mateur packet radio on shared simplex packet radio channels frequently suffers from l the well-known "hidden terminal problem" and the less well known but related prob em of the "exposed terminal. " This paper proposes a new scheme, Multiple Access c with Collision Avoidance (MACA), that could greatly relieve these problems. MACA an also be easily extended to provide automatic transmitter power control. This could increase the carrying capacity of a channel substantially.
Enhancing the optical lever sensitivity of microcantilevers for dynamic atomic force microscopy via integrated low frequency paddles

A method is presented to enhance the optical lever sensitivity in dynamic atomic force microscopy (AFM) by nearly an order of magnitude over a wide frequency bandwidth. This is achieved by fabricating or releasing a paddle with a soft hinge close to the free end of the AFM microcantilever such that the paddle resonance frequency is well below the fundamental resonance frequency of the microcantilever. We show a significant increase in signal to noise ratio when cantilever motion is observed at the paddle for AFM systems that are not limited by thermal noise. Also, any effects due to the excitation of the second eigenmode were decoupled by locating the paddle at the node of the second eigenmode. We use these probes for higher harmonic imaging in amplitude modulated AFM (AM–AFM) on a standard polymer blend made of polystyrene and low density polyethylene. We demonstrate significantly improved contrast in higher harmonic images when observing cantilever motion at the paddle. Thus this microcantilever design can improve significantly conventional cantilever performance for dynamic AFM and is compatible with low-cost, high yield microfabrication processes.
Stability of the higher-order structure of chicken-erythrocyte chromatin in solution.

A detailed hydrodynamic study of chicken erythrocyte chromatin as a function of ionic strength, and comparison with results reported earlier for rat liver chromatin [Butler, P.J.G. and Thomas, J. O. (1980) J. Mol. Biol. 140, 505–529; Thomas, J. O. and Butler, P.J.G. (1980) J. Mol. Biol. 144, 89-93] shows similar behaviour in the two cases, but quantitative differences indicate a greater stability of the chicken erythrocyte chromatin. The hydrodynamic method may thus provide a general assay for the stability in solution of the higher-order structure of chromatin–a helical coiling into a solenoid. When sedimentation coefficients of nucleosome oligomers of various lengths from chicken erythrocytes are measured as a function of ionic strength, two main changes in behaviour are observed. The first is between pentamer and hexamer as in rat liver chromatin, suggesting that the solenoid has 5–6 nucleosomes per turn. The longer repeat length of chicken erythrocyte chromatin (212 base pairs compared with 200 base pairs for rat liver chromatin) is thus accommodated into the solenoid without obvious change of structure. The second change in behaviour is a jump of about 9% in the sedimentation coefficient at ionic strength 50 mM for nucleosome oligomers above a critical size, which we attribute to the relative instability of higher order structure in long oligomers at lower ionic strength. In chicken erythrocyte chromatin this critical size is about 60 nucleosomes, compared with 50 nucleosomes in rat liver chromatin. The increased axial stability in the solenoid that this indicates possibly derives from the erythrocyte-specific histone H5, and would be expected in this chromatin which is virtually inactive in transcription.
The key theorem of learning theory with samples corrupted by zero-expect noise on chance space

Statistical learning theory has been regarded as one of the best theories for solving the small-sample learning problem on probability space. But it was difficult to deal with the problems on non-probability spaces and it mainly dealt with the noise-free case. In this paper, the key theorem with samples corrupted by zero-expect noise on chance space will be given and proven.
Krox20 hindbrain regulation incorporates multiple modes of cooperation between cis-acting elements

Developmental genes can harbour multiple transcriptional enhancers that act simultaneously or in succession to achieve robust and precise spatiotemporal expression. However, the mechanisms underlying cooperation between cis-acting elements are poorly documented, notably in vertebrates. The mouse gene Krox20 encodes a transcription factor required for the specification of two segments (rhombomeres) of the developing hindbrain. In rhombomere 3, Krox20 is subject to direct positive feedback governed by an autoregulatory enhancer, element A. In contrast, a second enhancer, element C, distant by 70 kb, is active from the initiation of transcription independent of the presence of the KROX20 protein. Here, using both enhancer knock-outs and investigations of chromatin organisation, we show that element C possesses a dual activity: besides its classical enhancer function, it is also permanently required in cis to potentiate the autoregulatory activity of element A, by increasing its chromatin accessibility. This work uncovers a novel, asymmetrical, long-range mode of cooperation between cis-acting elements that might be essential to avoid promiscuous activation of positive autoregulatory elements.
Identification : A Deep Approach and Comparative Study

Author identification has been one of the classical problem in Natural Language Processing. In this project, we tried different architectures of neural network to identify authors of the text. Each architecture has different requirements for the format of input and output data. Each architecture has its own merits and downside. The task of Author identification can be transformed into a multi-class classification problem given a vector representation of the document which contains all the information needed for author-identification. The objective is to effectively learn this vector-representation of the document.
Estimating Subglacial Water Geometry Using Radar Bed Echo Specularity: Application to Thwaites Glacier, West Antarctica

Airborne radar sounding is an established tool for observing the bed conditions and subglacial hydrology of ice sheets and glaciers. The specularity content of radar bed echoes has also been used to detect the hydrologic transition of a subglacial water system from a network of distributed canals to a network of concentrated channels beneath the Thwaites Glacier. However, the physical dimensions of the distributed water bodies in these networks have not been constrained by observations. In this letter, we use a variety of simple radar scattering, attenuation, and cross-sectional models to provide a first estimate of the subglacial water body geometries capable of producing the observed anisotropic specularity of the Thwaites Glacier catchment. This approach leads to estimates of ice/water interface root mean square roughnesses less than about 15 cm, thicknesses of more than about 5 cm, lengths of more than about 15 m, and widths between about 0.5 and 5 m.
The Capital Structure of Listed Companies in Poland

This paper examines the capital structure of listed firms in Poland, using firm-level panel data to study the determinants of leverage. Polish firms had extremely low leverage levels, suggesting a growing stock market and a potential reluctance of banks to grant loans to old and risky firms. The empirical exercise finds that large, new, foreign-owned firms, and firms with strong cash positions have higher levels of leverage. Finally, shareholder concentration has a neutral or even a beneficial influence on firm leverage. The nature of ownership may be primarily responsible for this finding.
Walking a fine line: Forensic mental health practitioners' experience of working with correctional officers

Abstract This paper explores mental health professionals' experiences working with correctional staff—ne aspect of an interdisciplinary phenomenological study of ethical practice in forensic psychiatry. Professionals describe this relationship as coexisting within the system, despite their often conflicting roles. In correctional officers' overt concern for custody and control, practitioners can perceive a “paramilitary mentality” with which they struggle to work. Conversely, practitioners can experience conflict with security personnel for appearing “too caring” or “too sympathetic” to offenders—being “con‐lovers. ” The balance practitioners establish between working with inmates and working alongside facility security is one of walking a fine line.
DNA Polymerase β Gene Expression: The Promoter Activator CREB-1 Is Upregulated in Chinese Hamster Ovary Cells by DNA Alkylating Agent-Induced Stress

Abstract The DNA alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) upregulates the level of the base excision DNA repair enzyme DNA polymerase β (β-pol) in several mammalian cell types. Previous studies suggested that β-pol expression is upregulated via a transcriptional mechanism that requires: the specific cAMP response element (CRE) in the β-pol core promoter; a phosphorylated form of CREbinding protein-1 (CREB-1); and cellular protein kinase A activity. A large family of CRE-binding proteins, i.e., the ATF/CREB factors, has been identified in various cell types. This study further examines the role of CREbinding proteins in regulating β-pol expression through study of Chinese hamster ovary (CHO) cells. In CHO cell nuclear extract, CREB-1 and ATF-1 are the predominant CRE-binding protein family members recognizing the CRE in the β-pol core promoter. The concentration of CREB-1 increases strongly in CHO cells after exposure to MNNG. In contrast, the level of ATF-1 does not change after MNNG treatment. Recombinant expression of CREB-1 in CHO cells is sufficient to increase expression of the endogenous β-pol gene, even in the absence of MNNG exposure. These results indicate that β-pol gene expression in CHO cells can be upregulated by CREB-1 and that the activation of β-pol gene expression in response to DNA alkylating agent exposure involves a strong increase in the level of CREB-1.
ORide: A Privacy-Preserving yet Accountable Ride-Hailing Service

In recent years, ride-hailing services (RHSs) have be- come increasingly popular, serving millions of users per day. Such systems, however, raise significant privacy concerns, because service providers are able to track the precise mobility patterns of all riders and drivers. In this paper, we propose ORide (Oblivious Ride), a privacy- preserving RHS based on somewhat-homomorphic en- cryption with optimizations such as ciphertext packing and transformed processing. With ORide, a service provider can match riders and drivers without learning their identities or location information. ORide offers rid- ers with fairly large anonymity sets (e.g., several thou- sands), even in sparsely populated areas. In addition, ORide supports key RHS features such as easy payment, reputation scores, accountability, and retrieval of lost items. Using real data-sets that consist of millions of rides, we show that the computational and network over- head introduced by ORide is acceptable. For example, ORide adds only several milliseconds to ride-hailing op- erations, and the extra driving distance for a driver is less than 0.5 km in more than 75% of the cases evaluated. In short, we show that a RHS can offer strong privacy guar- antees to both riders and drivers while maintaining the convenience of its services.
Direct reconstruction of cardiac PET kinetic parametric images using a preconditioned conjugate gradient approach.

PURPOSE Our research goal is to develop an algorithm to reconstruct cardiac positron emission tomography (PET) kinetic parametric images directly from sinograms and compare its performance with the conventional indirect approach. METHODS Time activity curves of a NCAT phantom were computed according to a one-tissue compartmental kinetic model with realistic kinetic parameters. The sinograms at each time frame were simulated using the activity distribution for the time frame. The authors reconstructed the parametric images directly from the sinograms by optimizing a cost function, which included the Poisson log-likelihood and a spatial regularization terms, using the preconditioned conjugate gradient (PCG) algorithm with the proposed preconditioner. The proposed preconditioner is a diagonal matrix whose diagonal entries are the ratio of the parameter and the sensitivity of the radioactivity associated with parameter. The authors compared the reconstructed parametric images using the direct approach with those reconstructed using the conventional indirect approach. RESULTS At the same bias, the direct approach yielded significant relative reduction in standard deviation by 12%-29% and 32%-70% for 50 × 10(6) and 10 × 10(6) detected coincidences counts, respectively. Also, the PCG method effectively reached a constant value after only 10 iterations (with numerical convergence achieved after 40-50 iterations), while more than 500 iterations were needed for CG. CONCLUSIONS The authors have developed a novel approach based on the PCG algorithm to directly reconstruct cardiac PET parametric images from sinograms, and yield better estimation of kinetic parameters than the conventional indirect approach, i.e., curve fitting of reconstructed images. The PCG method increases the convergence rate of reconstruction significantly as compared to the conventional CG method.
High expression of heat shock proteins and heat shock factor‐1 distinguishes an aggressive subset of clear cell renal cell carcinoma

Heat shock proteins (HSPs) are a group of molecules induced by a variety of environmental and pathophysiological stresses, including cancer. HSPs are implicated in the regulation of apoptosis and immunity in neoplasm. Transcription factor heat shock factor 1 (HSF1) acts as the master regulator to control HSP expression, and is therefore involved in tumorigenesis. The purpose of this study was to evaluate the expression and clinicopathological relevance of HSPs and HSF1 in clear cell renal cell carcinoma (ccRCC).
Managing the reputation of the banking industry after the global financial crisis: Implications of public anger, processing depth and retroactive memory interference for public recall of events

The global financial crisis of 2007/2008 devastated the reputation of the UK banking industry. This paper examines possible connections between the depth of an individual's cognitive processing of information about the banking industry's role in the onset of the crisis obtained from UK media (and elsewhere) and the subsequent extent and accuracy of the person's memory of events. Depth of processing was posited to depend on the level of an individual's feelings of anger at the banks' reported behaviour before and during the crisis and on the degree to which a person had suffered financially as a consequence of the crisis. A number of hypotheses were developed on the basis of Nabi's (1999) cognitive functional model and were tested via a survey of 413 members of the public in Greater London. It was further hypothesised that, because media coverage of the banks' involvement in the crisis was largely hostile, many members of the public attributed blame for the crisis mainly to the banks, resulting in extensive feelings of anger and hence deeper cognitive processing.
Effects of Probiotics on Acquisition and Spread of Multi-resistant Enterococci 1 2

16 17 Background 18 Ampicillin-resistant Enterococcus faecium (ARE) and vancomycin-resistant E. faecium (VRE) 19 are important nosocomial pathogens. We quantified effects of probiotics and antibiotics on 20 intestinal acquisition of ARE-colonization in patients hospitalized in two non-ICU wards with 21 high ARE prevalence. 22 Methods 23 In a prospective cohort study with cross-over design, all patients with a length of stay of >48h 24 were offered a multi-species probiotic product twice daily until discharge (4.5 months, 25 intervention period) or not (4.5 months, control period). Perianal ARE-carriage was determined 26 <48h after admission, twice weekly and <48h before discharge. First isolates were genotyped by 27 Multiple-Locus Variable-Number Tandem Repeat Analysis (MLVA). Risk factors for 28 acquisition were determined by Cox proportional hazards modelling, with special emphasis on 29 ecological post-antibiotic effects and delays between actual acquisition and culture positivity. 30 Results 31 Of 530 patients included, 94 (18%) were ARE-colonized on admission. Of the remaining 436 32 noncolonized patients, 92 acquired ARE-colonization: 28 (25%) of 110 probiotic users and 64 33 (20%) of 326 control patients (Χ 2 -test: p=0.325). In all, 661 ARE strains were isolated from 186 34 patients, of which 186 were genotyped. In both wards two MLVA-types (MT1 and MT159) were 35 responsible for >80% of acquisitions. Both MTs were genetically different from the probiotic E. 36 faecium strain. Antibiotics to which ARE is resistant (Hazard ratio (HR):7.73 [95%CI 4.5237 13.22], an ecological post-antibiotic effect (HR:7.11 [95%CI 3.10-16.30]) and age (HR:1.01 38 on N ovem er 3, 2017 by gest httpaac.asm .rg/ D ow nladed fom [95%CI 0.99-1.02]) were associated with ARE-acquisition. The HR of probiotics was 1.43 39 [95%CI: 0.88-2.34]. 40 Conclusion 41 In a setting with high selective antibiotic pressure, probiotics failed to prevent acquisition of 42 multi-resistant enterococci. 43 on N ovem er 3, 2017 by gest httpaac.asm . rg/ D ow nladed fom
Optimizing a Text Message Intervention to Reduce Heavy Drinking in Young Adults: Focus Group Findings

Background Recent trial results show that an interactive short message service (SMS) text message intervention, Texting to Reduce Alcohol Consumption (TRAC), is effective in reducing heavy drinking in non-treatment-seeking young adults, but may not be optimized. Objective To assess the usability of the TRAC intervention among young adults in an effort to optimize future intervention design. Methods We conducted five focus groups with 18 young adults, aged 18-25 years, who had a history of heavy drinking and had been randomized to 12 weeks of the TRAC intervention as part of a clinical trial. A trained moderator followed a semistructured interview guide. Focus groups were audiotaped, transcribed, and analyzed to identify themes. Results We identified four themes regarding user experiences with the TRAC intervention: (1) ease of use, (2) comfort and confidentiality, (3) increased awareness of drinking behavior, and (4) accountability for drinking behavior. Participants’ comments supported the existing features of the TRAC intervention, as well as the addition of other features to increase personalization and continuing engagement with the intervention. Conclusions Young adults perceived the TRAC intervention as a useful way to help them reduce heavy drinking on weekends. Components that promote ease of use, ensure confidentiality, increase awareness of alcohol consumption, and increase accountability were seen as important.
Resolving Pattern Ambiguity for English to Hindi Machine Translation Using WordNet

A common belief about natural language translation is that sentences of similar structure in the source language have translations that are similar in structure in the target language too. However, with respect to English to Hindi translation, this assumption does not hold well always. At least eleven different patterns can be found in the Hindi translation of English sentences in which the main verb is “have” or any of its declensions. This poses a serious problem for designing any English to Hindi translation system. Traditionally such variations are termed as “translation divergence”. Typically a study of divergence considers some standard translation pattern for a given input sentence structure. A translation is said to be a divergence if it deviates from this standard pattern. However, this is not the case with the abovementioned sentence structures. We term this ambiguity as “pattern ambiguity”. In this ongoing work we propose a rule-based scheme to resolve the ambiguity using word senses given by WordNet.