Miracle-dz/UniFAR-FTUs huggingface dataset:
Platelet Superoxide Dismutase in Migraine and Tension-Type Headache

Superoxide dismutase (SOD) is a radical-scavenging enzyme. We determined Cu, Zn-SOD concentrations and activities in platelets from subjects with migraine and tension-type headaches. Thirty migraine without aura (MWoA) patients, 9 migraine with aura (MWA) patients, and 53 tension-type headache patients were selected for study. Thirty healthy volunteers composed the control group. Concentrations of platelet SOD were determined using enzyme-linked immunosorbent assay techniques. The activity of platelet SOD was determined by measuring reductivity of nitroblue tetrazolium. Low concentrations of platelet SOD were found in patients with MWA and MWoA. Platelet SOD activity decreased in MWA patients but not in patients with MWoA or tension-type headaches. These findings suggest vulnerability to oxidative stress in patients with migraine. It is suggested that low platelet SOD levels may play an important role in the etiology of migraine.
The effects of an educational intervention on antipsychotic-induced weight gain.

PURPOSE To assess the effect of an educational intervention on antipsychotic-induced weight gain among patients with schizophrenia. DESIGN AND METHODS Quasi-experimental. Seventy patients with a DSM-IV diagnosis of schizophrenia or schizoaffective disorder entered this 6-month study condicted in the United States. All participants began receiving olanzapine treatment when they entered the study. The patients were then randomly assigned to an intervention group or a standard care group. Over the next 4-months, the intervention group participated in weekly psychoeducation classes focused on nutrition, exercise, and living a healthy lifestyle. Patients were followed for an additional 2 months to assess weight change. FINDINGS A statistically significant difference in weight change between the two groups was observed post-treatment and at endpoint. At endpoint, the mean weight change of the intervention group was -. 06 pounds, while the mean weight change in the standard care group was 9.57 pounds. In both groups, men gained significantly more weight than did women. CONCLUSIONS The results indicate that a structured educational intervention might have a positive effect on antipsychotic-induced weight gain among patients with schizophrenia.
Building Semantic Business Process Space for Agile and Efficient Business Processes Management: Ontology-Based Approach

Current practices of BPM suffer from the several fundamental problems, including difficulty with automatic discovery and the integration of business processes across organizations. Many studies un-covered that the main cause of these problems lies in insufficient semantics on business processes and suggested semantic business process management (SBPM) as a solution. Although building semantic business process space (SBPS) must be at the core of the SBPM approach to resolving the problems, most research on SBPM hardly deal with it seriously. Thus, this research shows how to build SBPS by incorporating semantics with business processes. The authors first illustrate the idea of building SBPS by defining a variety of generic and specific business process ontologies for the limited area of sales order process. They then explain how the SBPS satisfies the requirements for successful implementation of SBPM and demonstrate with a scenario how SBPM can be realized in the environment of SBPS for the agile and efficient BPM.
Life Goals Increase Self-regulation among Male Patients with Alcohol Use Disorder

ABSTRACT Background: Alcohol use disorder (AUD) has been conceptualized as a chronic self-regulation failure. Objectives: The aim of this study was to examine the most probable pathways related to self-regulation among patients with AUD. In this study, a hypothetical model was proposed that focused on the relationship between risk factors (extrinsic life goals, emotion dysregulation) and protective factors (intrinsic life goals, self-control, and abstinence self-efficacy). Methods: Male patients with AUD (N = 188) were recruited from alcohol centers of four psychiatric hospitals between March 2015 and September 2015. All participants completed psychological assessments, including the Future Oriented Goals Scale (FOGS), the Alcohol Abstinence Self-Efficacy Scale (AASE), the Brief Self-Control Scale (BSCS), and the Difficulties in Emotion Regulation Scale (DERS) as well as sociodemographic characteristics. Results: The final model was found to be a good fit to data. In testing indirect effects, it was shown that intrinsic life goals via emotion dysregulation, self-control, and alcohol abstinence self-efficacy decreased alcohol self-regulation failure. On the other hand, extrinsic life goals via these factors increased alcohol self-regulation failure. Conclusions/Importance: These results suggest that intrinsic goals might indirectly be the important and protective factors for AUD. Moreover, the findings implicate that self-regulation through goal setting may be necessary to alleviate symptoms and improve function among patients with AUD.
TECHNOLOGY SHOCKS AND URBAN EVOLUTIONS : DID THE COMPUTER REVOLUTION SHIFT THE FORTUNES OF U . S . CITIES ? ∗

In this paper, we show how differential rates of adaptation to an economy-wide technology shock—the Computer Revolution of the 1980s—have altered patterns in urban development across U.S. cities. Specifically, we document that the diffusion of computer technologies has contributed to a reversal in the task content of new occupational titles: while new types of work were still associated with routine tasks in the 1970s, additions of new work have mainly appeared in cognitive occupations and industries since 1980. Cities that historically specialized in cognitive work benefited differentially by shifting workers into new occupations, experiencing simultaneous relative increases in population, human capital and wages, subsequent to the Computer Revolution. Our results suggest that the recent divergence of U.S. cities can partly be explained by the complementarity of new technologies and historical skill endowments. JEL: R11, O31, O33
Histone Code Modifications Repress Glucose Transporter 4 Expression in the Intrauterine Growth-restricted Offspring*

We examined transcriptional and epigenetic mechanism(s) behind diminished skeletal muscle GLUT4 mRNA in intrauterine growth-restricted (IUGR) female rat offspring. An increase in MEF2D (inhibitor) with a decline in MEF2A (activator) and MyoD (co-activator) binding to the glut4 promoter in IUGR versus control was observed. The functional role of MEF2/MyoD-binding sites and neighboring three CpG clusters in glut4 gene transcription was confirmed in C2C12 muscle cells. No differential methylation of these three and other CpG clusters in the glut4 promoter occurred. DNA methyltransferase 1 (DNMT1) in postnatal, DNMT3a, and DNMT3b in adult was differentially recruited with increased MeCP2 (methyl CpG-binding protein) concentrations to bind the IUGR glut4 gene. Covalent modifications of the histone (H) code consisted of H3.K14 de-acetylation by recruitment of histone deacetylase (HDAC) 1 and enhanced association of HDAC4 enzymes. This set the stage for Suv39H1 methylase-mediated di-methylation of H3.K9 and increased recruitment of heterochromatin protein 1α, which partially inactivates postnatal and adult IUGR glut4 gene transcription. Further increased interactions in the adult IUGR between DNMT3a/DNMT3b and HDAC1 and MEF2D and HDAC1/HDAC4 and decreased association between MyoD and MEF2A existed. We conclude that epigenetic mechanisms consisting of histone code modifications repress skeletal muscle glut4 transcription in the postnatal period and persist in the adult female IUGR offspring.
Relative heading estimation under constant disturbances

Relative state estimation is an important component in multi-vehicle applications in GPS-denied environments. In this paper, we consider relative heading estimation between two Unmanned Aerial Systems (UAS). We examine observability properties of relative states between the two UAS in the presence of constant disturbances. We assume that UAS 2 measures UAS 1's position in its own frame. We first present observability conditions of the relative states when UAS 1 maintains a constant heading rate and a constant airspeed under the disturbance. We next establish state observability properties when UAS 1 is tracking a stationary ground target using a feedback control. In this case, the heading rate is non-constant. We design an extended Kalman filter (EKF) and conduct simulations to demonstrate its effectiveness in estimating the relative states.
Liver Abscess Caused by Infection with Community-Acquired Klebsiella quasipneumoniae subsp. quasipneumoniae

We report a case of pyogenic liver abscess caused by community-acquired Klebsiella quasipneumoniae subsp. quasipneumoniae. The infecting isolate had 2 prominent features of hypervirulent K. pneumoniae strains: the capsular polysaccharide synthesis region for K1 serotype and the integrative and conjugative element ICEKp1, which encodes the virulence factors yersiniabactin, salmochelin, and RmpA.
Radiologic-pathologic correlation of intraosseous lipomas.

673 ntraosseous lipomas are considered rare benign bone lesions, but with the advent of MR imaging more of these lesions are being recognized. Using Milgram’s histopathologic and radiologic classification [1], we divided intraosseous lipomas into three categories on the basis of their imaging characteristics. The appearance of these lesions on radiographs, CT scans, and MR images can vary as a result of their degree of involution and necrosis. Radiographically, these lesions may mimic other entities such as fibrous dysplasia, aneurysmal bone cysts, simple cysts, bone infarcts, and chondroid tumors. Blacksin et al. [2] showed that visualizing fat within these lesions aids in diagnosis. MR imaging and CT can be diagnostic whereas Radiologic–Pathologic Correlation of Intraosseous Lipomas
Negotiating trust: researching the practice of school business managers

Since 2002, successive governments have invested in national programmes to strengthen the potential of the school business manager (SBM) a member of the school workforce whose skills, knowledge and experience are well-placed to improve capacity and reduce the workload of headteachers in the operational, administrative and financial function of the school. Today there are thought to be approximately 13,000 SBMs across the country yet there remains a paucity of scholarly attention paid this section of the school workforce. This provided the impetus for the research discussed in this paper, a longitudinal case study that took an interpretivist perspective to explore the emergence and influence of the SBM in six schools across England.
Welfare Losses of Road Congestion

Countries around the world face a retirement crisis brought on by aging populations, declining birthrates, and fiscal shortfalls. As a result, policy makers increasingly seek to understand retirement savings patterns, a crucial component of the safety net for the elderly. Drawing on the 2014 Global Findex database, which provides individual-level data on the use of financial products in more than 140 countries, this paper examines how adults save for old age. It finds that about 25 percent of adults worldwide save for old age, with rates exceeding 35 percent in high-income Organisation for Economic Co-operation and Development economies and the East Asia and Pacific region. On average, men are slightly more likely than women to save for this purpose, but the gender gap is deeper in developing countries. Worldwide, saving for old age is more common among older adults, more educated adults, and adults who own accounts. Adults in countries with English legal origin, and with high savings rates, are also more likely to save for old age. The paper also finds that measures to increase trust in the financial system, such as the safety net/moral hazard index based on deposit insurance, lead to higher rates of saving for old age. Finally, the paper finds little evidence of substitution between pension system provisions and contribution rates with saving for old age.
Cocirculation of Two Distinct Lineages of Equine Influenza Virus Subtype H3N8

ABSTRACT Direct amplification and sequencing of the hemagglutinin (HA) genes of equine influenza virus subtype H3N8 was undertaken in order to characterize strains of this virus circulating in Sweden. The majority of viruses from outbreaks during 1997 analyzed belonged to the American lineage of H3 equine influenza, and one strain was shown to belong to the European lineage. Furthermore, it was shown that recent American-lineage strains are mutated at amino acid position 190 of the HA during serial passage in embryonated hens’ eggs. Host cell adaptation of these viruses thus takes place at antigenic region B of the HA.
Physical and Optical Properties of Atmospheric Aerosols in Summer at a Suburban Site in North China

ABSTRACTThe physical and optical properties of atmospheric aerosols at a suburban site in North China were continuously measured from July 20, 2014 to August 30, 2014. The particle number concentration (Na), mass concentration (Ma), geometric mean diameter (GMD), scattering coefficient (σsc), and Angstrom exponent (α) were calculated. The potential source contribution was also analyzed. The results revealed that the average Na, Ma, GMD, σsc, and α values reached 19653.2 cm–3, 17.7 µg m–3, 44.38 nm, 186.7 Mm–1, and 1.77, respectively, in non-rainy days and 14323.1 cm–3, 15.3 µg m–3, 44.98 nm, 226.9 Mm–1, and 1.87, respectively, in rainy days. Small-sized aerosols (< 100 nm) dominated the total aerosol numbers under clear conditions. The diurnal variation of Na showed one peak, usually appearing at 12:00, which could be correlated with new particle formation (NPF) events. Most NPF events began at 08:00–10:00 and continued until 12:00–14:00. The average particle formation rate (FR) and particle growth rate (GR) were 1.93 cm–3 s–1 and 7.24 nm h–1, respectively. The diurnal variation of Ma showed two peaks, at 7:00 and 21:00, which were caused by local or regional transport of urban plumes. A potential source contribution function (PSCF) analysis indicated that aerosol potential sources in Xinzhou were mainly concentrated in the relatively developed, densely populated areas, particularly in some areas to the east and southeast of Shanxi, and the PSCF values of these areas were higher than 0.6.
Purchase Decision Type Influences on Consumers’ Reliance: Brand-Related User-Generated Content

Consumers use brand-related user-generated content (UGC), such as online consumer reviews, for their pre-purchase information seeking. However, previous research on consumer information seeking has scarcely explored how purchase situations and product type influence consumers’ use of brand-related UGC. The purpose of this dissertation is to shed light on this area of research. In the first part of the study, Vaughn’s (1980; 1986) Foote, Cone, and Belding (FCB) grid, a popular product classification theory in advertising and consumer research, was updated based on a set of online surveys (N=1,104) that measured three purchase dimensions [i.e., purchase decision involvement (PDI), think/feel purchase, online/offline purchase context]. Multiple research hypotheses relevant to how purchase type influences one’s brandrelated UGC seeking were explored, based on another set of online surveys (N=391) in the second part of the study. A Cronbach’s alpha test revealed that the think/feel purchase dimension of the FCB grid measured two purchase constructs, rather than measuring a single construct. The grid model now consists of 118 up-to-date product examples and 35 categories, and has improved usability for research in other fields, because the study altered the theory’s dichotomous-looking dimensions into non-dichotomous variables. To examine the hypotheses, a linear mixed effect model was utilized for analysis, and the results indicated that the four dimensions (PDI, think purchase, feel purchase, online/offline purchase context) are all positively associated with one’s reliance on brand-related UGC. Furthermore, the study found several more associations between demographic factors and consumers’ reliance on brand-related UGC. Age, gender,
Packet Classification in Presence of Wildcard Expressions EE 384 X Course Project

Most conventional packet classifiers fail to work when both rules and keys contain wildcard expressions. Moreover, usually they find only the highest priority filter that matches the incoming packet. However, new networking applications such as network analyzers, intrusion detection systems, and load balancers, depend on generalized expressions for rules and keys using wildcards, and require all (or the first few) matching filters during classification. The most commonly proposed hardware based solutions to multi-match classification are TCAM based and, as a result, suffer from several disadvantages such as higher cost, power consumption, and inflexibility. This paper introduces a software based algorithm which is memory efficient, does not need expansion for rules and keys containing wildcards, is scalable, and provides multi-match results.
Do Credit Ratings Incorporate Business Linkages Along the Supply Chain?

This paper investigates whether credit ratings incorporate business linkages along the supply chain. We first document that a supplier’s bankruptcy risk is significantly associated with its major customer’s bankruptcy risk, thereby leading to a positive association between the credit ratings of the supplier and its major customer. However, the association between a supplier’s and its major customer’s credit rating changes is asymmetric. A supplier’s credit rating change is only positively associated with its major customer’s credit rating change when the customer has experienced a credit rating downgrade, but not when the customer has undergone an upgrade. This asymmetric effect is stronger when the customer-supplier relation lasts for a long time and when the customer is the largest customer of the supplier. We attribute this effect to the asymmetric payoff functions of the creditors, who focus on protecting downside risk rather than generating upside returns. Overall, our paper provides evidence that the customer’s credit worthiness influences the supplier’s credit ratings, suggesting that the debt market can be affected by the product market through the customer-supplier relations.
Metamodeling the Enhanced Entity-Relationship Model

A metamodel provides an abstract syntax to distinguish between valid and invalid models. That is, a metamodel is as useful for a modeling language as a grammar is for a programming language. In this context, although the Enhanced Entity-Relationship (EER) Model is the ”de facto” standard modeling language for database conceptual design, to the best of our knowledge, there are only two proposals of EER metamodels, which do not provide a full support to Chen’s notation. Furthermore, neither a discussion about the engineering used for specifying these metamodels is presented nor a comparative analysis among them is made. With the aim at overcoming these drawbacks, we show a detailed and practical view of how to formalize the EER Model by means of a metamodel that (i) covers all elements of the Chen’s notation, (ii) defines well-formedness rules needed for creating syntactically correct EER schemas, and (iii) can be used as a starting point to create Computer Aided Software Engineering (CASE) tools for EER modeling, interchange metadata among these tools, perform automatic SQL/DDL code generation, and/or extend (or reuse part of) the EER Model. In order to show the feasibility, expressiveness, and usefulness of our metamodel (named EERMM), we have developed a CASE tool (named EERCASE), which has been tested with a practical example that covers all EER constructors, confirming that our metamodel is feasible, useful, more expressive than related ones and correctly defined. Moreover, we analyze our work against the related ones and present our final remarks.
A qualitative meta‐synthesis: public health nurses role in the identification and management of perinatal mental health problems

AIM To report findings of a systematic review and meta-synthesis of qualitative studies exploring public health nurses' perceptions and experiences of identifying and managing women with perinatal mental health (PMH) problems. BACKGROUND Public health nurses play a key role in supporting women who experience PMH problems and several qualitative studies have explored their role. DESIGN Systematic review and meta-synthesis DATA SOURCES: A comprehensive search was developed and multiple databases were searched from 2000-2015. REVIEW METHODS Studies that employed qualitative methods to explore experiences of public health nurses in identifying and managing women with PMH problems were included. Two reviewers independently assessed the methodological quality of studies. Themes, concepts and interpretations were extracted and synthesized using the process of thematic analysis. RESULTS Fifteen papers including 14 unique qualitative studies were included. Two overarching themes were identified: 'conceptualization and detection of PMH problems' and 'barriers and facilitators to management'. The former of these comprised several subthemes including the use of formal screening tools vs. clinical intuition and challenges encountered in detection. The latter theme, barriers to management included availability of referral pathways and time. In terms of facilitators, training, public health nursing interventions, support groups and referral pathways were identified as factors that optimize management. CONCLUSIONS Public health nurses use a variety of methods to identify women with PMH problems. However, several support structures are needed to optimize management including access to appropriate referral pathways, support groups and relationship continuity.
The Drivers of Consumer Complaint Behaviors in the Service Industry

This study examines the determinants of consumer complaint behaviors (CCB) in the service industry. The taxonomy of CCB is reviewed and confirmed; the main effect and interaction effect of predictors of CCB are defined and checked. This study postulates that the types of service failure, namely, failure in procedure and failure in outcome, have a significant main effect and interaction effect on the Voice response of CCB. The hypotheses are tested and the results are discussed.
Genetic drift in univariate marginal distribution algorithm

Like Darwinian-type genetic algorithms, there also exists genetic drift in Univariate Marginal Distribution Algorithm (UMDA). Since the universal analysis of genetic drift in UMDA is very difficult, in this paper, we just approach a certain kind of problem (WOneMax Problem). For WOneMax Problem, The individual space in UMDA can be denoted as a full binary tree, and the selecting process in UMDA can be considered as a process of cutting branch. We employ this binary tree to calculate the probability change of each variable between two adjacent generations. Comparing this change with our experimental data, we find that when the population size is limited, there exists genetic drift in UMDA. In order to avoid genetic drift, we model the probability of each variable as a signal with noise, and then use smoothing filter to eliminate genetic drift. Numerical results show this method is effective.