Miracle-dz/UniFAR-FTUs huggingface dataset:
Towards scalable X10 based link prediction for large scale social networks

The use of social application such as Twitter or FaceBook becomes popular in recent years. In particular, Twitter increases the number of the users rapidly from 2009 as the place that users can tweet anything in 140 characters. In the area of social network analysis, the user network of Twitter is frequently analyzed. Haewoon, et.al.,[1] analyzed the Twitter user network from various point of view in 2009, and they show that the Twitter user network has some different feature from conventional social networks. Bong- won, et.al., also made a collection of 74 millions tweets in 2010, and investigated the influence that "retweet" gives for diffusion of the information. Such analysis not only reveal the unique characteristics of Twitter user network, but also make some networking service such as finding users who are similar to someone, or the recommendation of commodities by using tweet information. There are some analysis such as clustering which needs entire data of the network. However, since social networks are increasing day by day, it becomes impossible to obtain the entire network by crawling. As a solution of this problem, there is the network analysis called link prediction. This enables to predict true network from a given part of the network. If we use link prediction, we can recover the entire network from the network data which we already obtained, and apply some analysis such as clustering to predicted net- work, then we may get the approximate result of the analysis for the entire network. In our research, we implemented one of the link prediction algorithm named Link Propagation in X10, which is a parallel programming language. And evaluated its scalability and precision with Twitter user network data.
Hypolipidemic effect of MeOH extract of Bambusae Caulis in Taeniam in hyperlipidemia induced by Triton WR-1339 and high cholesterol diet in rats

Hyperlipidemia has been implicated in atherosclerosis which is the leading cause of death among world population and resulting from lipid metabolic changes is a major cause of atherosclerosis. Bambusae Caulis in Taeniam belongs to Bambusaceae is the stem of Phyllostachys nigra (Lodd.) Munro var. henonis (Bean) Stapf of Phyllostachys bambusoides Siebold et Zuccarini, the perennial evergreen tree. The green middle layer of stem is dried in string-shape I shadow after the bark had been removed. In this study, the effects of middle layer of PN, PB, PP, and BCT on rat with hyperlipidemia, induced by Triton WR-1339 and high cholesterol diet were investigated. We measured plasma levels of triglyceride, total cholesterol, low-density lipoprotein (LDL)-cholesterol, and high-density lipoprotein (HDL)-cholesterol as measure of its hyperlipidemic effects. As a result, all of the Bambusae Caulis in Taeniam was reduced total cholesterol, LDL. Inhibition rate on LDL-oxidation, hACAT-1, and hACAT-2 was increased dose-dependently. Therefore all of the Bambusae Caulis in Taeniam is a good candidate for the treatment on Triton WR-1339 and high cholesterol diet-induced blood circulatory disorders, obesity, and hyperlipidemia.
Searching NCBI's dbSNP Database

The Single‐Nucleotide Polymorphism database (dbSNP) is a variation database at the National Center for Biotechnology Information (NCBI). It is a public repository of submitted nucleotide variations and is part of NCBI's search and retrieval system Entrez. This unit describes two basic protocols to search dbSNP effectively, one to perform a text‐based search and another to perform a sequence‐based search. The unit also describes one of the result display formats called GeneView to obtain information about all submitted SNPs in a particular gene. Curr. Protoc. Bioinform. 32:1.19. 1‐1.19. 18. © 2010 by John Wiley & Sons, Inc.
Graph-Based Manifold Frequency Analysis for Denoising

We propose a new framework for manifold denoising based on processing in the graph Fourier frequency domain, derived from the spectral decomposition of the discrete graph Laplacian. Our approach uses the Spectral Graph Wavelet transform in order to per- form non-iterative denoising directly in the graph frequency domain, an approach inspired by conventional wavelet-based signal denoising methods. We theoretically justify our approach, based on the fact that for smooth manifolds the coordinate information energy is localized in the low spectral graph wavelet sub-bands, while the noise affects all frequency bands in a similar way. Experimental results show that our proposed manifold frequency denoising (MFD) approach significantly outperforms the state of the art denoising meth- ods, and is robust to a wide range of parameter selections, e.g., the choice of k nearest neighbor connectivity of the graph.
Digital games : a context for cognitive development

1. Introduction: Digital Games as a Context for Cognitive 1 Development, Learning, and Developmental Research Fran C. Blumberg, Shalom M. Fisch This introductory chapter outlines reasons why developmental psychologists should care about children s and adolescents learning in the context of digital games and previews each of the chapters composing the volume. 2. The Challenge of Audience Reception: A Developmental 11 Model for Educational Game Engagement John L. Sherry The author presents a model for research and development of educational games based on uses and gratifications theory from communication science and on developmental science and cognitive science findings. 3. Engagement States and Learning from Educational Games 21 Kirby Deater-Deckard, Mido Chang, Michael E. Evans The authors present an innovative and comprehensive model of engagement states experienced during learning and apply that model to research on educational game development. 4. Applying Developmental Theory and Research to the 31 Creation of Educational Games Glenda Revelle An overview is presented of key theoretical observations and research based insight regarding children s development, including discussion of practical implications for game design. 5 . The Impact of Recreational Video Game Play on Children s 41 and Adolescents Cognition Fran C. Blumberg, Elizabeth A. Altschuler, Debby E. Almonte, Maxwell I. Mileaf This chapter reviews research concerning the cognitive benefits of video game play among children and adolescents and their impressions of video games as learning tools. 6. Electronic Gaming and the Obesity Crisis 51 Sandra L. Calvert, Amanda E. Staiano, Bradley J. Bond The authors examine the positive contributions of digital game play to combating the current pediatric obesity crisis. 7. Cross-Platform Learning: On the Nature of Children s 59 Learning from Multiple Media Platforms Shalom M. Fisch This author surveys recent studies examining cross-platform learning (i.e., learning from combined use of several media platforms) and how such learning compares to learning from one medium. 8. Commentary Games for Learning: Vast Wasteland or a 71 Digital Promise? Michael H. Levine, Sarah E. Vaala This chapter reviews benefi ts of digital game play research and development for improving educational attainment among the nation s youth, and identifies some directions for future research. INDEX 83
Cortico-striatal Function in Individuals at Genetic Risk for Schizophrenia

Evidence demonstrates that individuals with schizophrenia have impaired corticostriatal functioning. Non-psychotic relatives of patients with schizophrenia exhibit a subset of the deficits present in schizophrenia patients, suggesting that there are cognitive endophenotypes of this disorder and that these deficits appear to be associated with genetic liability for schizophrenia. In order to determine if a deficit in corticostriatal functioning is an endophenotype for schizophrenia, it is important to investigate the idea that genetic risk for schizophrenia is associated with impairment in striatal dependent tasks. Therefore, we will use both behavioral measures and fMRI to assess differences in performance level and pattern of brain activation associated with different striatal-dependent tasks to investigate the corticostriatal function of relatives of patients with schizophrenia. Both behavioral and fMRI studies will be conducted in healthy adolescent and adult relatives schizophrenic individuals and controls using cognitive and motor skill learning tasks. The behavioral studies will measure performance and function of two different corticostriatal loops and will investigate the developmental course for the behavior pattern of relatives of schizophrenia patients. The fMRI studies will expand the results of the behavioral studies and determine whether there is a difference in the pattern of brain activation between the adolescent relatives, adolescent controls, adult relatives, and adult controls. This research makes a novel contribution in that it demonstrates that individuals with genetic liability for schizophrenia exhibit deficits in corticostriatal function. Because these individuals do not have the disease, their performance gives insights into whether corticostriatal function is an endophonotype of schizophrenia, independent of the effects of medication and the illness itself and also leads to an increased understanding of the neural mechanisms of schizophrenia and advances the search for the treatment of this severe disorder.
The Scottish Emergency Care Summary--an evaluation of a national shared record system aiming to improve patient care: technology report.

BACKGROUND In Scotland, out-of-hours calls are all triaged by the National Health Service emergency service (NHS24) but the clinicians receiving calls have no direct access to patient records. OBJECTIVE To improve the safety of patient care in unscheduled consultations when the usual primary care record is not available. TECHNOLOGY The Emergency Care Summary (ECS) is a record system offering controlled access to medication and adverse reactions details for nearly every person registered with a general practice in Scotland. It holds a secure central copy of these parts of the general practitioner (GP) practice record and is updated automatically twice daily. It is accessible under specified unplanned clinical circumstances by clinicians working in out-of-hours organisations, NHS24 and accident and emergency departments if they have consent from the patient and a current legitimate relationship for that patient's care. APPLICATION We describe the design of the security model, management of data quality, deployment, costs and clinical benefits of the ECS over four years nationwide in Scotland, to inform the debate on the safe and effective sharing of health data in other nations. EVALUATION Forms were emailed to 300 NHS24 clinicians and 81% of the 113 respondents said that the ECS was helpful or very helpful and felt that it changed their clinical management in 20% of cases. CONCLUSION The ECS is acceptable to patients and helpful for clinicians and is used routinely for unscheduled care when normal medical records are unavailable. Benefits include more efficient assessment and reduced drug interaction, adverse reaction and duplicate prescribing.
Tyrosine phosphorylation of WW proteins

A number of key regulatory proteins contain one or two copies of the WW domain known to mediate protein–protein interaction via proline-rich motifs, such as PPxY. The Hippo pathway components take advantage of this module to transduce tumor suppressor signaling. It is becoming evident that tyrosine phosphorylation is a critical regulator of the WW proteins. Here, we review the current knowledge on the involved tyrosine kinases and their roles in regulating the WW proteins.
Transmission of correlated sources over a fading multiple access channel

In this paper we address the problem of transmission of correlated sources over a fading multiple access channel (MAC). We provide sufficient conditions for transmission with given distortions. Next these conditions are specialized to a Gaussian MAC (GMAC). Transmission schemes for discrete and Gaussian sources over a fading GMAC are considered. Various power allocation strategies are also compared.
Monitoring of rice crop growth from space using the ERS-1 C-band SAR

This communication presents preliminary results of the first attempt to monitor rice crop growth from space from transplanting to harvesting with an active microwave instrument using ERS-1 C-band SAR. The variation of /spl sigma//sup 0/ for a test rice field in the Akita Prefectural College of Agriculture obtained from multitemporal SAR data is evaluated by comparing with ground truth data of the rice crop condition. The feasibility is shown of estimating the number of days after transplanting and hence the rice crop growth stage from the /spl sigma//sup 0/ measurement. Correlation analysis suggests a close relationship between /spl sigma//sup 0/ and the two dimensional extent of the rice crops. >
Notch1 and Notch2 Have Opposite Effects on Embryonal Brain Tumor Growth

The role of Notch signaling in tumorigenesis can vary; Notch1 acts as an oncogene in some neoplasms, and a tumor suppressor in others. Here, we show that different Notch receptors can have opposite effects in a single tumor type. Expression of truncated, constitutively active Notch1 or Notch2 in embryonal brain tumor cell lines caused antagonistic effects on tumor growth. Cell proliferation, soft agar colony formation, and xenograft growth were all promoted by Notch2 and inhibited by Notch1. We also found that Notch2 receptor transcripts are highly expressed in progenitor cell-derived brain tumors such as medulloblastomas, whereas Notch1 is scarce or undetectable. This parallels normal cerebellar development, during which Notch2 is predominantly expressed in proliferating progenitors and Notch1 in postmitotic differentiating cells. Given the oncogenic effects of Notch2, we analyzed its gene dosage in 40 embryonal brain tumors, detecting an increased copy number in 15% of cases. Notch2 gene amplification was confirmed by fluorescence in situ hybridization in one case with extremely high Notch2 mRNA levels. In addition, expression of the Notch pathway target gene Hes1 in medulloblastomas was associated with significantly shorter patient survival (P = 0.01). Finally, pharmacological inhibition of Notch signaling suppresses growth of medulloblastoma cells. Our data indicate that Notch1 and Notch2 can have opposite effects on the growth of a single tumor type, and show that Notch2 can be overexpressed after gene amplification in human tumors.
Reduction of acquisition time through optimal component presentation at an assembly workstation

An effective presentation of components at the workstation can have a significant impact in reducing assembly time. Our goal is to develop optimal presentation plans based on design for assembly theory. The assembly factors recognized as relevant to both parts acquisition and assembly workstation layout are recognition, orientation, weight, and handling distance. This study considers a single manual operator at an assembly station, with the components in rectangular bins of differing sizes and aspect ratios. Ninety degree rotations of the bins are allowed for minimizing potential handling distance. The assembly task is modeled with multiple assembly points representing the final location of the components. Components may or may not be preoriented in the bins, with preorientation removing the recognition and orientation time penalties. The problem formulation employs Mixed Integer NonLinear Programming (M1NLP), and numerical evidence suggests an NP-hard problem. Heuristic methods reduce computational effort to practical levels for realistic assembly tasks. Our results show that numerical optimization of assembly workstation layout can reduce the expected level of difficulty over random or manual workstation design methods.
Allergen and endotoxin exposure in a companion animal hospital

Background Exposure to allergens, both in general and occupational environments, is known to result in sensitisation and exacerbation of allergic diseases, while endotoxin exposure might protect against allergic diseases. This may be important for veterinarians and co-workers. However, exposure levels are mostly unknown. Objective We investigated the allergen and endotoxin exposure levels of veterinary medicine students and workers in a companion animal hospital. Methods Airborne and surface dust was collected using various sampling methods at different locations. Allergen levels in extracts were measured with sandwich ELISAs and/or the multiplex array for indoor allergens (MARIA). Endotoxin was determined by limulus amebocyte lysate (LAL) assay. Results Fel d 1 (Felis domesticus), Can f 1 (Canus familiaris) and endotoxin were detected in all except stationary samples. The geometric mean (GM) level of personal inhalable dust samples for Fel d 1 was 0.3 ng/m3 (range: below lower limit of detection (<LOD) to 9.4), for Can f 1 3.6 ng/m3 (<LOD to 73.3) and for endotoxin 4.4 EU/m3 (<LOD to 75). Exposure levels differed significantly between job titles, with highest allergen exposure for student assistants in the intensive care unit (Fel d 1, GM 1.5 ng/m3; Can f 1, GM 18.5 ng/m3), and highest endotoxin exposure for students (GM 10.1 EU/m3). Exposure levels in dust captured by diverse sampling methods correlated with each other (p<0.05). Conclusion Allergen exposure likely occurs during veterinary practice, with relatively low endotoxin levels. Future research should investigate dose–response relationship between airborne allergen exposure and health effects.
Can groups solve the problem of over-bidding in contests?

This study reports an experiment that examines whether groups can better comply with theoretical predictions than individuals in contests. Our experiment replicates previous findings that individual players significantly overbid relative to theoretical predictions, incurring substantial losses. There is high variance in individual bids and strong heterogeneity across individual players. The new findings of our experiment are that groups make 25% lower bids, their bids have lower variance, and group bids are less heterogeneous than individual bids. Therefore, groups receive significantly higher and more homogeneous payoffs than individuals. We elicit individual and group preferences toward risk using simple lotteries. The results indicate that groups make less risky decisions, which are possible explanations for lower bids in contests. Most importantly, we find that groups learn to make lower bids from communication and negotiation between group members.
ISAR imaging based on divariate empirical mode decomposition and Wigner-Ville Distribution

An Inverse Synthetic Aperture Radar (ISAR) imaging method based on Bivariate Empirical Mode Decomposition (BEMD) and Wigner-Ville Distribution (WVD) is proposed in this paper. This method effectively reduces the cross-term interference and has less false frequency, leading to better quality of reconstructed image. Simulation results verify the better performance of proposed BEMD-WVD method compared with WVD method and Complex Empirical Mode Decomposition (CEMD) with WVD (CEMD-WVD) method.
Diets high in fermentable protein and fibre alter tight junction protein composition with minor effects on barrier function in piglet colon

Protein fermentation end products may damage the colonic mucosa, which could be counteracted by dietary inclusion of fermentable carbohydrates (fCHO). Although fermentable crude protein (fCP) and fCHO are known to affect microbial ecology, their interactive effects on epithelial barrier function are unknown. In the present study, in a 2 × 2 factorial experiment, thirty-two weaned piglets were fed low-fCP/low-fCHO (14·5 % crude protein (CP)/14·5 % total dietary fibre (TDF)), low-fCP/high-fCHO (14·8 % CP/16·6 % TDF), high-fCP/low-fCHO (19·8 % CP/14·5 % TDF) and high-fCP/high-fCHO (20·1 % CP/18·0 % TDF) diets. After 21–23 d, samples of proximal and distal colonic mucosae were investigated in Ussing chambers with respect to the paracellular and transcytotic passages of macromolecules and epithelial ion transport. The high-fCHO diets were found to reduce the permeability of the distal colon to the transcytotic marker horseradish peroxidase (HRP, 44 kDa; P <0·05) and also reduce the paracellular permeation of N-hydroxysuccinimide-biotin into the submucosa (443 Da; P <0·05), whereas that of HRP was decreased by the high-fCP diets (P <0·01). Short-circuit current (active ion transport), transepithelial resistance (barrier function) and charge selectivity were largely unaffected in both the segments. However, the high-fCP diets were found to suppress the aldosterone-induced epithelial Na channel activity (P <0·01) irrespective of fCHO inclusion. The high-fCP diets generally reduced the expression of colonic claudin-1, claudin-2 and claudin-3 (P <0·01), while that of claudin-4 was increased by the high-fCHO diets (P <0·01). The high-fCHO diets also altered the ratio between occludin forms (P <0·05) and increased the expression of tricellulin in the proximal colon, which was not observed with high-fCP diets. In conclusion, dietary fCHO and fCP exerted few and largely independent effects on functional measurements, but altered tight junction protein composition in a compensatory way, so that colonic transport and barrier properties were only marginally affected.
Efficient Architectures for Streaming DSP Applications

— In this paper we focus on algorithms and reconfigurable tiled architectures for streaming DSP applications. The tile concept has a number of advantages: (1) depending on the requirements more or less tiles can be switched on/off, (2) the tile structure fits well to future IC process technologies, more tiles will be available in advanced process technologies, but the complexity per tile stays the same, (3) the tile concept is fault tolerant, faulty tiles can be discarded and (4) tiles can be configured in parallel. Because processing and memory is combined in the tiles, tasks can be executed efficiently (locality of reference). There are a number of application domains that can be considered as streaming DSP applications, for example wireless baseband processing and phased array radar systems. In this paper the key characteristics of streaming DSP applications are highlighted, and the characteristics of the processing architectures to efficiently support these types of applications are addressed.
Traffic Signal Timings Optimization Using Fuzzy Logic Controller

-In our day to day life, increasing the number of vehicles like motorcycle, car, bus, van and truck etc. very rapidly. As a result outcome of traffic blocking and enormous problems in metro cities. Due to traffic jamming problem some large issues are found such as pollution, wastage of time, fuel, and accidents. Traffic jamming arises terribly often time switch in the contemporary world that has an effect on the means of life and introduces such a large amount of issues and challenge. To resolve this problem by using traffic signal timing optimization is the better solution. In this research work proposed a fuzzy logic controller for multiple intersection model. The issues in traffic trade are mostly characterize by the worldwide, uncertain and unsure parameters. Such kind of parameters fuzzy logic technique is suitable advance for traffic control problem. A fuzzy logic traffic control simulation model is developed and tested using MATLAB software. The Performance of fuzzy logic based on traffic signal timing optimization compared with fixed time controller rising the research field. The performance of Fuzzy Logic Controller is found to be similar to that of the fixed controller in normal traffic conditions. However, in heavy traffic conditions, Fuzzy Logic Controller results shows 30% decrease on average delay of cars waiting at the intersection and 10% improvement on total number of cars served at the intersection over the same simulation period compared to the fixed time controller. The results show that there is a huge improvement that can be realized by using Fuzzy Logic Controller in controlling traffic flow at multiple intersections. Fuzzy logic is very useful method for transportation in future use.