Miracle-dz/UniFAR-FTUs huggingface dataset:
Emotional Empathic Responses to Dynamic Negative Affective Stimuli Is Gender-Dependent

Empathy entails the ability to recognize emotional states in others and feel for them. Since empathy does not take place in a static setting, paradigms utilizing more naturalistic, dynamic stimuli instead of static stimuli are perhaps more suited to grasp the origin of this highly complex social skill. The study was set up to test the effect of stimulus dynamics and gender on empathic responses. Participants were 80 healthy volunteers (N = 40 males) aged 22.5 years on average. Behavioral empathy was tested with the multifaceted empathy test, including static emotional stimuli, and the multidimensional movie empathy test (MMET), including dynamic stimuli. Findings showed emotional empathy (EE) responses were higher to negative emotional stimuli in both tasks, i.e., using static as well as dynamic stimuli. Interestingly a gender-dependent response was only seen in the MMET using dynamic stimuli. It was shown that females felt more aroused and were more concerned with people in negative affective states. It was concluded that the MMET is suited to study gender differences in EE.
cDNA-AFLP Reveals a Striking Overlap in Race-Specific Resistance and Wound Response Gene Expression Profiles

The tomato Cf-9 gene confers resistance to races of the fungal pathogen Cladosporium fulvum expressing the Avr9 gene. cDNA amplified fragment length polymorphism analysis was used to display transcripts whose expression is rapidly altered during the Avr9- and Cf-9–mediated defense response in tobacco cell cultures. Diphenyleneiodonium was used to abolish the production of active oxygen species during gene induction. Of 30,000 fragments inspected, 290 showed altered abundance, of which 263 were induced independently of active oxygen species. cDNA clones were obtained for 13 ACRE (for Avr9/Cf-9 rapidly elicited) genes. ACRE gene induction occurred in the presence of cycloheximide. Avr9 induced ACRE gene expression in leaves. Surprisingly, ACRE genes were also rapidly but transiently induced in leaves in response to other stresses. The amino acid sequences of some ACRE proteins are homologous to sequences of known proteins such as ethylene response element binding protein transcription factors, the N resistance protein, a calcium binding protein, 13-lipoxygenase, and a RING-H2 zinc finger protein. Rapid induction of ACRE genes suggests that they play a pivotal role during plant defense responses.
Performance Analysis of Various Feature Detector and Descriptor for Real-Time Video based Face Tracking

This paper presents the performance analysis of various contemporary feature detector and descriptor pair for real time face tracking. These feature detectors/descriptors are mostly used in image matching applications. Some feature detectors/descriptors like STAR, FAST, BRIEF, FREAK, and ORB can also be used for SLAM applications due to their high performance. However using only one of these feature detectors for object tracking may not provide good accuracy due to various challenges in tracking like abrupt change in object motion, non-rigid object structure, change in appearance of object, occlusions in the scene and camera motion. But it can be combined other object tracking algorithm to improve the overall tracking accuracy. In this paper we have measured the tracking speed and accuracy of these feature detectors in real time video for face tracking using parameters like average number of detected key points, average detection time of key-point, frame per second and number of matches using OpenCV. General Terms Object tracking, Image matching.
Cost-efficient residential load scheduling in smart grid

To improve the economical efficiency of the residential electricity consumption, in this paper we introduce a novel concept of cost efficiency-based residential load scheduling framework. The cost efficiency is defined as a ratio of consumer's total consumption benefit and its total electricity payment during a certain period. We develop a cost-efficient load scheduling algorithm for the demand-side's day-ahead bidding process based on a fractional programming approach. We found that the proposed scheduling algorithm can effectively reflect and affect user's consumption behavior and achieve the optimal cost-efficient energy consumption profile. For practical consideration, we also take into account the service fee in calculating the cost-efficiency in practical smart grid applications, and analyse its effect on the cost efficiency. Simulation results confirm that the proposed algorithm significantly improves consumer's cost efficiency compared with the conventional payoff maximization algorithm. It also shows that a higher service fee will considerably decrease the cost efficiency.
Warburg and Crabtree Effects in Premalignant Barrett's Esophagus Cell Lines with Active Mitochondria

Background Increased glycolysis is a hallmark of cancer metabolism, yet relatively little is known about this phenotype at premalignant stages of progression. Periodic ischemia occurs in the premalignant condition Barrett's esophagus (BE) due to tissue damage from chronic acid-bile reflux and may select for early adaptations to hypoxia, including upregulation of glycolysis. Methodology/Principal Findings We compared rates of glycolysis and oxidative phosphorylation in four cell lines derived from patients with BE (CP-A, CP-B, CP-C and CP-D) in response to metabolic inhibitors and changes in glucose concentration. We report that cell lines derived from patients with more advanced genetically unstable BE have up to two-fold higher glycolysis compared to a cell line derived from a patient with early genetically stable BE; however, all cell lines preserve active mitochondria. In response to the glycolytic inhibitor 2-deoxyglucose, the most glycolytic cell lines (CP-C and CP-D) had the greatest suppression of extra-cellular acidification, but were able to compensate with upregulation of oxidative phosphorylation. In addition, these cell lines showed the lowest compensatory increases in glycolysis in response to mitochondrial uncoupling by 2,4-dinitrophenol. Finally, these cell lines also upregulated their oxidative phosphorylation in response to glucose via the Crabtree effect, and demonstrate a greater range of modulation of oxygen consumption. Conclusions/Significance Our findings suggest that cells from premalignant Barrett's esophagus tissue may adapt to an ever-changing selective microenvironment through changes in energy metabolic pathways typically associated with cancer cells.
Role of Transforming Growth Factor β in Uterine Fibroid Biology

Uterine fibroids (UFs) are benign tumors of the female genital tract made of the smooth muscle of the uterus. UF growth depends mostly on the influence of the steroid hormones and selected growth factors. Transforming growth factor β (TGF-βs) is a polypeptide that consists of three isoforms: TGF-β1, TGF-β2, and TGF-β3. At present, TGF-β is considered to be one of the key factors in the pathophysiology of UFs. It plays a major role in cellular migration within the tumor, stimulates tumor growth, and enhances tumor metabolism. As a consequence of various dependencies, the synthesis and release of TGF-β in a UF tumor is increased, which results in excessive extracellular matrix production and storage. High concentrations or overexpression of TGF-β mediators may be responsible for clinically symptomatic UFs. The aim of this review was to check the available evidence for the influence of the TGF-β family on UF biology. We conducted their search in PubMed of the National Library of Medicine with the use of the following selected keywords: “uterine fibroid”, “leiomyoma”, and “transforming growth factor β”. After reviewing the titles and abstracts, more than 115 full articles were evaluated. We focused on the TGF-β-related molecular aspects and their influence on the most common symptoms that are associated with UFs. Also, we described how the available data might implicate the current medical management of UFs.
An Approach for Online Analysis usingExpectation Maximization

Opinion rich web resources such as discussion forums, review sites and blogs which are bulky and are available in digital form. For the purpose of customer and business perspective, the task of scanning these reviews manually is computational burden. Hence, to process reviews automatically and summarizing them in suitable form is more efficient. The distinguished problem of producing opinion summary addresses is how to determine the mood, sentiment or opinion expressed in the review with respect to a numerical feature value. In this paper, the focus is on the main task of opinion mining called as opinion summarization. The extraction of product feature, technical feature value and opinion are critical for opinion summarization as they affect the performance significantly. The proposed approach consists of a software system in which mining of product feature, technical feature value and opinion is performed. The main motto of this software system is to recognize the technical feature value depending on which the reviews are summarized. This software is helpful for humans to understand the technical values expressed in the reviews.
Modulation by permeant ions of Mg2+ inhibition of NMDA‐activated whole‐cell currents in rat cortical neurons

Whole‐cell N‐methyl‐d‐aspartate (NMDA)‐activated currents were recorded from cultured rat cortical neurons. We report here a powerful effect of changing permeant ion concentrations on the voltage‐dependent inhibition by external Mg2+ (Mg2+ (Mgo2+) of these currents. Internal Cs+ (Csi+) affected Mgo2+ inhibition of the NMDA‐activated currents in a voltage‐dependent manner. A decrease in Csi+ concentration ([Cs+]i) from 125 to 8 mm reduced Mgo2+ IC50 by 1.4‐fold at −105 mV and by 11.5‐fold at – 15 mV. A decrease in external Na+ (Nao+ concentration ([Na+]o) also reduced Mgo2+ IC50. This effect was voltage independent. A decrease in [Na+]o from 140 to 70 mm reduced Mgo2+ IC50 by 1.4‐fold at–105 mV and by 1.6‐fold at–15 mV. Varying external Ca2+ (Cao2+) concentrations ([Ca2+]o) from 0.1 to1 mm did not affect Mgo2+ inhibition, even though changing [Ca2+]o in the same range strongly influenced the magnitude of NMDA‐activated currents in the absence of Mgo2+. However, increasing [Ca2+]o to higher concentrations (2–20 mm) greatly increased Mgo2+ IC50 at hyperpolarized voltages. These data are consistent with a model in which Nai+ and Csi+ modulate Mgo2+ inhibition of NMDA‐activated currents by occupying external permeant ion binding sites. The Mgo2+ IC50 values reported here are similar to Mgo2+KD values calculated from previous single‐channel measurements of Mgo2+ blocking kinetics. This similarity implies that Mgo2+ does not affect gating while blocking the channel.
DLBP: A novel descriptor for depth image based face recognition

This paper presents a novel descriptor for face depth images, generalizing the well-known Local Binary Pattern (LBP), in order to enhance its discriminative power for smooth depth images. The proposed descriptor is based on detecting shape patterns from face surfaces and enables accurate and fast description of shape variation in depth images. It is in the same form as conventional LBP, so patterns can be readily combined to form joint histograms to represent depth faces. The descriptor is computationally very simple, rapid and it is totally training-free. When we associate our descriptor in a face recognition scheme based on nearest neighbor classifier, it shows its discriminative power in depth based face recognition comparing to the conventional LBP and other extensions proposed for 3D face recognition. Many experiments are conducted on different databases in order to evaluate our method.
Prevalence of and associated risk factors for fluoroquinolone-resistant Neisseria gonorrhoeae in California, 2000-2003.

BACKGROUND Rates of fluoroquinolone-resistant Neisseria gonorrhoeae (QRNG) are increasing worldwide and in California. METHODS As a supplement to established surveillance, the investigation of QRNG in California included expanded surveillance in southern California, with in-depth interviews of patients (who had QRNG during the period of January 2001-June 2002) and a cross-sectional study of patients at 4 sexually transmitted diseases clinics with gonococcal isolates that underwent susceptibility testing (for the period of July 2001-June 2002). RESULTS The rate of QRNG increased from <1% in 1999 to 20.2% in the second half of 2003. The 2001-2002 expanded surveillance demonstrated that 66 (4.9%) of 1355 isolates were resistant to fluoroquinolones; the majority of these infections occurred after August 2001. Cross-sectional analysis of 952 patients with gonorrhea revealed that the prevalence of QRNG varied geographically during 2001-2002, with the highest rate being in southern California (8.9%) and the lowest being in San Francisco (3.6%). The QRNG prevalence was 8.6% among men who have sex with men (MSM), 5.1% among heterosexual men, and 4.3% among women. Although risk factors for QRNG varied by clinic, multivariate analysis demonstrated independent associations with race/ethnicity, recent antibiotic use, and MSM. CONCLUSIONS The emergence and spread of QRNG in California appeared to evolve from sporadic importation to endemic transmission among both MSM and heterosexuals. Monitoring of both the prevalence of and risk factors for QRNG infections is critical for making treatment recommendations and for developing interventions to interrupt transmission.
ROBTIC: An On-chip Instruction Cache Design for Low Power Embedded Systems

The on-chip instruction cache is a potential power hungry component in embedded systems due to its large chip area and high access-frequency. Aiming at reducing power consumption of the on-chip cache, we proposed a Reduced One-Bit Tag Instruction Cache (ROBTIC), where the cache size is judiciously reduced and the cache tag field only contains the least significant bit of the full tag. We developed a cache operational control scheme for ROBTIC so that with the one-bit cache tag, the program locality can still be efficiently exploited. For applications where most of the memory accesses are localized, our cache is able to achieve similar performance as a traditional full-tag cache; however, the power consumption of the cache can be significantly reduced due to the much smaller cache size, narrower tag array (just one bit), and tinier tag comparison circuit being used. The experiments on a set of benchmarks demonstrate that our approach can reduce up to 25.8% power consumption and 30.9% area of the traditional cache when the cache size is fixed at 32 instructions. With the cache size customization, a further 48% power saving can be achieved.
Roscovitine is a proteostasis regulator that corrects the trafficking defect of F508del‐CFTR by a CDK‐independent mechanism

The most common mutation in cystic fibrosis (CF), F508del, causes defects in trafficking, channel gating and endocytosis of the CF transmembrane conductance regulator (CFTR) protein. Because CF is an orphan disease, therapeutic strategies aimed at improving mutant CFTR functions are needed to target the root cause of CF.
Output Interference and Strength Based Mirror Effect in Recognition Memory

The strength based mirror effect (SBME) refers to higher hit rates and lower false alarm rates for strongly encoded items. The SBME has been explained by two alternative mechanisms: differentiation and criterion shift. The differentiation account posits that as the memory traces are strengthened, the memory for the items is less noisy and therefore are less confusable with the stored memory traces. The criterion shift account, on the other hand, suggests that the tendency to endorse a test item differs between strong and weak test lists. When participants receive a test after studying a strong list of items, they require more evidence to endorse an item. This account suggests that the SBME is observed due to the decision processes rather than memory. One strong piece of evidence for the criterion shift account is that the SBME is observed after studying a mixed list in which half of the items are strengthened and the other half are not. The differentiation mechanism can not account for the SBME observed after a mixed study list. However, recent findings of output interference (OI) in recognition memory have been explained by encoding at retrieval, which suggest that differentiation can also take place at retrieval. This suggests a third possible explanation for the SBME might be encoding during retrieval. In a series of experiments, we investigated the effect of strengthening items at study on OI in pure and mixed list paradigms. The results from the pure list paradigm (Experiment 1) showed both OI and the SBME as well as an interaction between OI and the SBME, as the item-noise models predicted. The results from the mixed list paradigm (Experiment 2-4) showed that the SBME was observed only when participants were informed of the strength of the list that they would be tested on. This finding adds constraints to the criterion shift account which states that participants shift their criterion to endorse a test item according to the type of the test list and that shift in the criterion causes the SBME. These results suggest that both criterion shift and differentiation account could be playing a role in the SBME after studying pure lists, and that only criterion shift account plays a role in SBME after studying a mixed list, but only when participants are explicitly aware of the testing conditions.
CABot3: A Simulated Neural Games Agent

CABot3, the third Cell Assembly roBot, is an agent implemented entirely in simulated neurons. It is situated in a virtual 3D environment and responds to commands from a user in that environment. It parses the user’s natural language commands to set goals, uses those goals to drive its planning system, views the environment, moves through it, and learns a spatial cognitive map of it. Some systems (e.g. parsing) perform perfectly, but others (e.g. planning) are not always successful. So, CABot3 acts as a proof of concept, showing a simulated neural agent can function in a 3D environment.
Acute plasma tau relates to prolonged return to play after concussion

Objective: To determine whether tau changes after sport-related concussion (SRC) relate to return to play (RTP). Methods: Collegiate athletes underwent preseason plasma sampling and cognitive testing and were followed. After a SRC (n = 46), athletes and controls (n = 37) had sampling at 6 hours, and at 24 hours, 72 hours, and 7 days after SRC. A sample of 21 nonathlete controls were compared at baseline. SRC athletes were grouped by long (>10 days, n = 23) and short (≤10 days, n = 18) RTP. Total tau was measured using an ultrasensitive immunoassay. Results: Both SRC and athlete controls had significantly higher mean tau at baseline compared to nonathlete healthy controls (F101,3 = 19.644, p < 0.01). Compared to SRC athletes with short RTP, those with long RTP had higher tau concentrations overall, after controlling for sex (F39,1 = 3.59, p = 0.022), compared to long RTP athletes, at 6 (p < 0.01), 24 (p < 0.01), and 72 hours (p = 0.02). Receiver operator characteristic analyses showed that higher plasma tau 6 hours post-SRC was a significant predictor of RTP >10 days (area under the curve 0.81; 95% confidence interval 0.62–0.97, p = 0.01). Conclusions: Elevated plasma tau concentration within 6 hours following a SRC was related to having a prolonged RTP, suggesting that tau levels may help inform RTP.
Energy Characterization of a Security Module in ARM Processor

This article shows the results obtained during simulations that measured runtime and energy consumption of a security module (SEMO) when it executes in ARM processor. For the simulations, we considered the impacts of four algorithms (i.e. RSA, SHA-1, Random Numbers Generator and AES). We have used the Sim-Panalyzer simulator and obtained an average energy consumption (x2 Joules) and runtime (x26000 cycles). We also show the impact of some compiler optimizations in the energy consumption of the AES algorithm.
Identification of a novel herpesvirus associated with cutaneous ulcers in a fisher (Martes pennanti)

On December 8, 2008, a male fisher (Martes pennanti) housed in a quarantine enclosure at the St-Félicien Zoo was found dead with multiple skin ulcers on the muzzle and plantar pads. At necropsy, no major findings were found, and a specific cause of death was not determined microscopically. However, at the borders of ulcerated sites, there were increased numbers of koilocytes, with perinuclear vacuolation and nuclear enlargement. A pan-herpesvirus nested polymerase chain reaction (PCR) assay was conducted, and an expected PCR product of 230 nucleotides was obtained within tissues collected from around the skin ulcers. Other tissues, including intestines and pool of lung, liver, and kidney, tested negative. The obtained PCR amplicon was sequenced and was highly related to the partial viral DNA polymerase (DPOL) gene of Mustelid herpesvirus 1. Virus isolation was negative, and no virion was detected by electron microscopy. The pathogenic potential of this novel herpesvirus and its role in the death of the fisher are unknown.
STUDIES ON THE PATHOGENESIS OF FEVER WITH INFLUENZAL VIRUSES

A substance with pyrogenic properties appears in the blood streams of rabbits made febrile by the intravenous inoculation of the PR8 strain of influenza A and Newcastle disease viruses (NDV). By means of a technique involving passive transfer of sera from animals given virus to recipient rabbits, the titer of circulating pyrogen was found to be closely correlated with the course of fever produced by virus. Certain properties of the pyrogen are described which differentiate it from the originally injected virus and suggest that the induced pyrogen is of endogenous origin. These properties resemble those of endogenous pyrogens occurring in other forms of experimental fever. The source of virus-induced pyrogen is unknown. In vitro incubation of virus with various constituents of the circulation did not result in the appearance of endogenous pyrogen. Granulocytopenia induced by HN2 failed to influence either fever or the production of endogenous pyrogen in rabbits injected with NDV. Similarly, the intraperitoneal inoculation of NDV into prepared exudates did not modify the febrile response. These findings do not lend support to the possibility that the polymorphonuclear leukocyte is a significant source of endogenous pyrogen in virus-induced fever. It is concluded that the liberation of an endogenous pyrogen from some as yet undefined source is an essential step in the pathogenesis of fever caused by the influenza group of viruses.
Where and How Duplicates Occur in the Web

In this paper we study duplicates on the Web, using collections containing documents of all sites under the . cl domain that represent accurate and representative subsets of the Web. We identify duplicate and near-duplicate documents in our collections, studying the distribution of documents in clusters of duplicates. We also study the occurrence of duplicates in both parts of our Web graphs - connected and disconnected component - aiming to identify where duplicates occur more frequently. We originally show that the number of duplicates in the Web is expressively greater than the number of duplicates in the connected component of the Web graph. Works that previously estimated the number of duplicates in the Web used collections of connected components of the Web. In those cases the sample of the Web was biased