Miracle-dz/UniFAR-FTUs huggingface dataset:
Variation in personality and fitness in wild female baboons

Studies of personality in nonhuman primates have usually relied on assessments by humans and seldom considered the function of the resulting “trait” classifications. In contrast, we applied exploratory principal component analysis to seven behaviors among 45 wild female baboons over 7 y to determine whether the personality dimensions that emerged were associated with measures of reproductive success. We identified three relatively stable personality dimensions, each characterized by a distinct suite of behaviors that were not redundant with dominance rank or the availability of kin. Females scoring high on the “Nice” dimension were friendly to all females and often grunted to lower-ranking females to signal benign intent. “Aloof” females were aggressive, less friendly, and grunted primarily to higher-ranking females. “Loner” females were often alone, relatively unfriendly, and also grunted most often to higher-ranking females. Aloof and Loner females were rarely approached by others. Personality dimensions were correlated in different ways with three measures previously shown to be associated with fitness: stress levels and two behavioral indices reflecting the closeness of dyadic bonds formed by individuals. Females who scored high on Nice had high composite sociality indices (CSI) and stable partner preferences, whereas females who scored high on Aloof had lower CSI scores but significantly more stable partner preferences. Loner females had significantly lower CSI scores, less stable partner preferences, and significantly higher glucocorticoid levels. It remains to be determined which of the Nice or Aloof personality dimensions is more adaptive, or whether variation is maintained by contrasting effects on fitness.
A clustering-based matrix factorization method to improve the accuracy of recommendation systems

Matrix approximation is a common model-based approach to collaborative filtering in recommender systems. However, due to data sparsity, it is difficult for current approaches to accurately approximate unknown rating values, which may cause low-quality recommendations. In this paper, we proposed a modified latent factor model to predict the missing ratings and generate accurate recommendations. The proposed method is able to overcome data sparsity and also improving matrix approximation by integrating clustering and transfer learning techniques in a unified framework. The performance of the proposed method was evaluated on two real-world benchmarks and results show its superiority compare to the state-of-the-art methods.
81 WAVELET SHRINKAGE OF ITCH RESPONSE DATA

This article addresses the problem of denoising piecewise constant functions by using both an jump-tolerant moving average and Haar wavelet shrinkage. The piecewise constant functions are contaminated with Poisson-like noise and are measurements of perceived itch by human subjects in an experiment to relate perceived itch to bloodflow in response to histamine iontophoresis. We show that the translation-invariant wavelet transform with universal wavelet shrinkage provides a fast and automatic method for producing good estimates of the underlying perceived itch and that the method is superior to the jump-tolerant moving average and standard wavelet shrinkage. The article then looks in more detail at the noise structure of the signals and highlights some new wavelet techniques that might be useful.
The Handbook of Research Synthesis and Meta-Analysis

The chapter on stochastically dependent effect sizes by Gleser and Olkin (2009) in The handbook of research synthesis and meta-analysis (2nd ed.) describes. Download Here: tinyurl.com/ohnxrcn When the first edition of The Handbook of Research. In book: Handbook of research methods in social and personality psychology A meta-analysis is literally an analysis of analyses, but conventionally the term.
Glucose, lactate, and lactic dehydrogenase activity in normal interstitial fluid and that of solid mouse tumors.

Microscale assays of protein, glucose, lactate (LA), and the total lactic dehydrogenase (LDH) activity in samples of free interstitial fluid from solid unicentric tumor transplants in mice are reported. The values have been compared with those found in plasma and intraperitoneal fluid from normal and tumor-bearing mice. The tumor fluids contained greater amounts of protein, LA, and LDH than did normal interstitial fluid, even when this was obtained from the same tumor-bearing mice. Highest values were found in the central fluid of young tumors. The glucose content of tumor fluids was considerably lower than that of normal intraperitoneal fluid or plasma. It is concluded that the composition of the interstitial fluid of solid tumors is very different from that of normal interstitial fluid. The reasons for this are discussed with reference to the metabolism and permeability of tumor cells, and to the vascular supply and interstitial transport facilities in tumors.
Quality of life and criminal recidivism in forensic outpatients with personality disorders : a good lives approach.

• A submitted manuscript is the version of the article upon submission and before peer-review. There can be important differences between the submitted version and the official published version of record. People interested in the research are advised to contact the author for the final version of the publication, or visit the DOI to the publisher's website. • The final author version and the galley proof are versions of the publication after peer review. • The final published version features the final layout of the paper including the volume, issue and page numbers.
Empathy, Pain and Attention: Cues that Predict Pain Stimulation to the Partner and the Self Capture Visual Attention

Empathy motivates helping and cooperative behaviors and plays an important role in social interactions and personal communication. The present research examined the hypothesis that a state of empathy guides attention towards stimuli significant to others in a similar way as to stimuli relevant to the self. Sixteen couples in romantic partnerships were examined in a pain-related empathy paradigm including an anticipation phase and a stimulation phase. Abstract visual symbols (i.e., arrows and flashes) signaled the delivery of a Pain or Nopain stimulus to the partner or the self while dense sensor event-related potentials (ERPs) were simultaneously recorded from both persons. During the anticipation phase, stimuli predicting Pain compared to Nopain stimuli to the partner elicited a larger early posterior negativity (EPN) and late positive potential (LPP), which were similar in topography and latency to the EPN and LPP modulations elicited by stimuli signaling pain for the self. Noteworthy, using abstract cue symbols to cue Pain and Nopain stimuli suggests that these effects are not driven by perceptual features. The findings demonstrate that symbolic stimuli relevant for the partner capture attention, which implies a state of empathy to the pain of the partner. From a broader perspective, states of empathy appear to regulate attention processing according to the perceived needs and goals of the partner.
Escherichia coli Cytotoxic Necrotizing Factor 1 Effaces Microvilli and Decreases Transmigration of Polymorphonuclear Leukocytes in Intestinal T84 Epithelial Cell Monolayers

ABSTRACT Cytotoxic necrotizing factor type 1 (CNF1), a 110-kDa toxin-like protein from pathogenic Escherichia coli strains, induces an actin cytoskeleton reorganization consisting of the formation of prominent stress fibers by permanent activation of the small GTP-binding protein Rho. Since p21Rho regulates tight-junction permeability and perijunctional actin reorganization in epithelial intestinal cells (A. Nusrat, M. Giry, J. R. Turner, S. P. Colgan, C. A. Parkos, E. Lemichez, P. Boquet, and J. L. Madara, Proc. Natl. Acad. Sci. USA 92:10629–10633, 1995), we used polarized T84 epithelial intestinal cell monolayers to examine whether CNF1 could affect microvillus structure, transepithelial resistance, and polymorphonuclear leukocyte (PMN) transmigration. Incubation of T84 cells with CNF1 did not influence transepithelial resistance, suggesting that barrier function and surface polarity were not affected by the toxin. However, CNF1 effaced intestinal cell microvilli and induced a strong decrease of PMN transepithelial migration in either the luminal-to-basolateral or the basolateral-to-luminal direction. CNF1 could thus be a virulence factor exhibiting a new type of combined activity consisting of effacing of microvilli and occlusion of the epithelial barrier to PMNs. Attenuated transepithelial migration of PMNs could result in the enhanced growth and protection of luminal bacteria.
Attacks and Countermeasures on 802.16: Analysis and Assessment

The IEEE 802.16 technology, commonly referred to as WiMAX, gains momentum as an option for broadband wireless communication access. So far, several research works focus on the security of the 802.16 family of standards. In this context, the contribution of this paper is twofold. First, it provides a comprehensive taxonomy of attacks and countermeasures on 802.16. Each attack is classified based on several factors, e.g. its type, likelihood of occurrence, impact upon the system etc. and its potential is reviewed with reference to the standard. Possible countermeasures and remedies proposed for each category of attacks are also discussed to assess their effectiveness. Second, a full-scale assessment study of indicative attacks that belong to broader attack classes is conducted in an effort to better comprehend their impact on the 802.16 realm. As far as we are aware of, this is the first time an exhaustive and detailed survey of this kind is attempted.
A transformational approach to generating application-specific environments

Current software development environments tend to lie at opposite ends of a spectrum: at one extreme are specialized application generators; at the other are general-purpose programming environments. The former provide strong support for system development and reuse, but are costly to build and available only for limited domains. The latter provide weak support, but are generally available and universally applicable. We describe a technique for automating the production of application-specific environments that lie between these two extremes. The key idea is that these environments can be derived from general-purpose programming environments by a process of structured transformation. We describe a tool for performing these transformations. It provides a set of formal operators for specializing a description of a general-purpose environment; as operators are applied, the system semi-automatically builds a set of transformation rules used to translate application-specific programs into those of the original general-purpose environment. The output of the tool is an application-specific environment together with a program transformer that provides execution semantics for programs written in that environment.
Children's Experiences of Separation from Parents as a Consequence of Migration

This paper discusses the findings of a study highlighting the impact of parental migration on children in Trinidad & Tobago. Both qualitative & quantitative methods were used to measure depression indicators with a population of 146 children aged 12-16 years. In-depth structured interviews were also conducted with 24 children & their caregivers. The study demonstrated that children separated from parents because of migration were more than twice as likely as other children to have emotional problems although their economic status was improved. One-third had serious levels of depression or interpersonal difficulties affecting schooling & leading in some cases to suicidal ideation. Differences were found in relation to gender & ethnicity. In addition to separation through migration, several children had experienced serial losses, e.g. bereavement, parental divorce, parental imprisonment, or change of caregiver. Resiliency factors included school performance & belief in family reunification. This investigation identifies the implications for Social Work Education & Policy Reform. It points to the discursive possibilities of child-centred approaches to the construction of knowledge & argues for the inclusion of such approaches within a theory & practice framework based on empowerment. 2 Charts, 18 References. Adapted from the source document.
A fully-autonomous aerial robotic solution for the 2016 International Micro Air Vehicle competition

In this paper, a fully-autonomous quadrotor aerial robot for solving the different missions proposed in the 2016 International Micro Air Vehicle (IMAV) Indoor Competition is presented. The missions proposed in the IMAV 2016 competition involve the execution of high-level missions such as entering and exiting a building, exploring an unknown indoor environment, recognizing and interacting with objects, landing autonomously on a moving platform, etc. For solving the aforementioned missions, a fully-autonomous quadrotor aerial robot has been designed, based on a complete hardware configuration and a versatile software architecture, which allows the aerial robot to complete all the missions in a fully autonomous and consecutive manner. A thorough evaluation of the proposed system has been carried out in both simulated flights, using the Gazebo simulator in combination with PX4 Software-In-The-Loop, and real flights, demonstrating the appropriate capabilities of the proposed system for performing high-level missions and its flexibility for being adapted to a wide variety of applications.
Audio retrieval based on perceptual similarity

Given a short query audio clip, the goal of audio retrieval is to automatically fetch all similar clips from a given audio database. Different from traditional audio similarity which is mainly based on priori knowledge of objective reality, this paper proposes to use a more subjective method to measure the perceptual similarity between audio clips. These perceptual features focus on users' personal experience, which can be very helpful for audio retrieval across different databases. In addition, indexing and audio matching methods are introduced to speed up the retrieval process. Experimental results on four different datasets are conducted to evaluate the effectiveness and efficiency of our proposed approaches.
Motive Edici Faktörlerin Çalışanların İş Performansına ve İşten Ayrılma Niyetine Etkisi

The purpose of research is to analyse the effect of motivational factors on job performance and turnover intention. The research type is empirical, design is causal, method of data collection is questionnaire.The research is conducted on 130 personnel of a government organization privatized in Turkey. As first result, wage, physical conditions and cooperation between personnel are negatively effecting turnover intention. As second result, job itself, wage and physical conditions of the motivation factors effect job performance positively. Besides, it is revealed that factors motivating personnel are, respectively, job itself, cooperation, wages and labour conditions, relation with chief, career possibility and rewarding.
A Study of Replacement Algorithms for Virtual-Storage Computer

One of the basic limitations of a digital computer is the size of its available memory. 1 In most cases, it is neither feasible nor economical for a user to insist that every problem program fit into memory. The number of words of information in a program often exceeds the number of cells (i.e., word locations) in memory. The only way to solve this problem is to assign more than one program word to a cell. Since a cell can hold only one word at a time, extra words assigned to the cell must be held in external storage. Conventionally, overlay techniques are employed to exchange memory words and external-storage words whenever needed; this, of course, places an additional planning and coding burden on the programmer. For several reasons, it would be advantageous to rid the programmer of this function by providing him with a “virtual” memory larger than his program. An approach that permits him to use a sufficiently large address range can accomplish this objective, assuming that means are provided for automatic execution of the memory-overlay functions.
Direct Binding of C-terminal Region of p130 to SH2 and SH3 Domains of Src Kinase (*)

p130 is a major tyrosine-phosphorylated protein that tightly binds v-Crk in v-crk-transformed cells and v-Src in v-src-transformed cells. The “substrate domain” of p130 contains 15 possible Src homology (SH) 2-binding motifs, most of which conform to the binding motif for the Crk SH2 domain. Another region near its C terminus contains possible binding motifs for the Src SH2 domain and proline-rich sequences that are candidates for SH3-binding sites. Using GST fusion proteins, we revealed that both SH2 and SH3 domains of Src bind p130, whereas v-Crk binds p130 through its SH2 domain. We located the binding site of p130 for the Src SH3 domain at the sequence RPLPSPP in the region near its C terminus. Mutations within this sequence or at Tyr of p130 caused a significant reduction in the association of p130 with Src, and no association was detected when both of them were deleted. The kinase activity in v-Crk-transformed cells was also associated with p130 through this region. On the other hand, the deletion of the substrate domain abolished the binding with v-Crk. The association through the C-terminal region of p130 with Src kinase may facilitate effective hyperphosphorylation of tyrosine residues in the substrate domain of p130, resulting in the binding of SH2-containing molecules to p130.
Osteopontin Is a Novel Downstream Target of SOX9 With Diagnostic Implications for Progression of Liver Fibrosis in Humans

Osteopontin (OPN) is an important component of the extracellular matrix (ECM), which promotes liver fibrosis and has been described as a biomarker for its severity. Previously, we have demonstrated that Sex‐determining region Y‐box 9 (SOX9) is ectopically expressed during activation of hepatic stellate cells (HSC) when it is responsible for the production of type 1 collagen, which causes scar formation in liver fibrosis. Here, we demonstrate that SOX9 regulates OPN. During normal development and in the mature liver, SOX9 and OPN are coexpressed in the biliary duct. In rodent and human models of fibrosis, both proteins were increased and colocalized to fibrotic regions in vivo and in culture‐activated HSCs. SOX9 bound a conserved upstream region of the OPN gene, and abrogation of Sox9 in HSCs significantly decreased OPN production. Hedgehog (Hh) signaling has previously been shown to regulate OPN expression directly by glioblastoma (GLI) 1. Our data indicate that in models of liver fibrosis, Hh signaling more likely acts through SOX9 to modulate OPN. In contrast to Gli2 and Gli3, Gli1 is sparse in HSCs and is not increased upon activation. Furthermore, reduction of GLI2, but not GLI3, decreased the expression of both SOX9 and OPN, whereas overexpressing SOX9 or constitutively active GLI2 could rescue the antagonistic effects of cyclopamine on OPN expression. Conclusion: These data reinforce SOX9, downstream of Hh signaling, as a core factor mediating the expression of ECM components involved in liver fibrosis. Understanding the role and regulation of SOX9 during liver fibrosis will provide insight into its potential modulation as an antifibrotic therapy or as a means of identifying potential ECM targets, similar to OPN, as biomarkers of fibrosis. (HEPATOLOGY 2012;56:1108–1116)
Motive Structures and Violence among Young Globalization Critics: A Statistical Typology of the Motives for Protest at the 2007 G8 Summit

The results of a questionnaire survey of 3,578 young protesters aged 15 to 24 were used to create a typology of the motive structures of the young globalization critics who participated in protests against the G8 summit in Heiligendamm in June 2007. Eight groups with different motive structures identified using cluster analysis reveal the spectrum of motives of the young demonstrators, ranging from social and political idealism to hedonistic fun-seeking and nationalist motives. Despite the diversity of motives, two cross-cluster motives can be identified: the results clearly show that the majority of respondents were motivated by political idealism and rejected violence. Two overlapping minorities were found: one where political idealism was largely lacking, and another where violence was a prominent motive.
Ionising Radiation Immediately Impairs Synaptic Plasticity-Associated Cytoskeletal Signalling Pathways in HT22 Cells and in Mouse Brain: An In Vitro/In Vivo Comparison Study

Patients suffering from brain malignancies are treated with high-dose ionising radiation. However, this may lead to severe learning and memory impairment. Preventive treatments to minimise these side effects have not been possible due to the lack of knowledge of the involved signalling pathways and molecular targets. Mouse hippocampal neuronal HT22 cells were irradiated with acute gamma doses of 0.5 Gy, 1.0 Gy and 4.0 Gy. Changes in the cellular proteome were investigated by isotope-coded protein label technology and tandem mass spectrometry after 4 and 24 hours. To compare the findings with the in vivo response, male NMRI mice were irradiated on postnatal day 10 with a gamma dose of 1.0 Gy, followed by evaluation of the cellular proteome of hippocampus and cortex 24 hours post-irradiation. Analysis of the in vitro proteome showed that signalling pathways related to synaptic actin-remodelling were significantly affected at 1.0 Gy and 4.0 Gy but not at 0.5 Gy after 4 and 24 hours. We observed radiation-induced reduction of the miR-132 and Rac1 levels; miR-132 is known to regulate Rac1 activity by blocking the GTPase-activating protein p250GAP. In the irradiated hippocampus and cortex we observed alterations in the signalling pathways similar to those in vitro. The decreased expression of miR-132 and Rac1 was associated with an increase in hippocampal cofilin and phospho-cofilin. The Rac1-Cofilin pathway is involved in the modulation of synaptic actin filament formation that is necessary for correct spine and synapse morphology to enable processes of learning and memory. We suggest that acute radiation exposure leads to rapid dendritic spine and synapse morphology alterations via aberrant cytoskeletal signalling and processing and that this is associated with the immediate neurocognitive side effects observed in patients treated with ionising radiation.