Miracle-dz/UniFAR-FTUs huggingface dataset:
Diaqua(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-3-ide-4-carboxylato-κ2 N 3,O 4)(1,10-phenanthroline-κ2 N,N′)manganese(II)

The title compound, [Mn(C5H2N2O4)(C12H8N2)(H2O)2], was synthesized by the reaction of manganese(II) acetate and orotic acid in the presence of 1,10-phenanthroline. The crystal structure exhibits intermolecular N—H⋯O and O—H⋯O hydrogen bonds . The Mn coordination environment consists of an N3O3 donor set in an octahedral geometry.
Energy Efficient Zonal Stable Election Protocol for WSNs

-In this project work for wireless sensor networks (WSNs), we propose a energy efficient routing protocol Zonal Stable Election Protocol (ZSEP). By using this protocol we divide the network into 3 zones the total nodes into normal nodes, advanced nodes one zone consists of normal nodes and two zones consists of advanced nodes on the basis of their energy levels. In this network we install a Base Station (BS) in the center of the sensing area. If the nodes are in normal region they use direct communication, if the nodes are in advanced nodes they form a Cluster Head (CH) and transmit the data through the CH. This protocol showed improved energy parameters when compared with previous protocol
The quality of therapeutic alliance between patient and provider predicts general satisfaction.

OBJECTIVES Therapeutic alliance has been proposed as an ideal patient-provider relationship. The Kim Alliance Scale (KAS) measures the quality of therapeutic alliance, including patient empowerment. The objectives were to refine KAS and to measure the relationship between therapeutic alliance and patients' general satisfaction. METHODS A total of 601 evaluable patients was recruited, 304 patients in exploratory series and 297 patients in validation series. Patients completed a demographics questionnaire, the KAS, and Patient Satisfaction with Health Care Provider Scale. RESULTS Using the exploratory series, KAS was refined into a 16-item KAS-R consisting of collaboration, integration, empowerment, and communication subscales. Internal consistency reliability of KAS-R was 0.89. Hierarchical multiple regression analyses of the two series showed that KAS-R accounts for 35% to 36% of the variance in general satisfaction scores. CONCLUSIONS Therapeutic alliance, as measured by KAS-R, predicted approximately one-third of patients' general satisfaction and empowerment was a significant predictor variable.
Neonatal BCG Immunization Followed by DNAhsp65 Boosters: Highly Immunogenic but not Protective Against Tuberculosis – a Paradoxical Effect of the Vector?

A new tuberculosis vaccine is urgently needed. Prime‐boost strategies are considered very promising and the inclusion of BCG is highly desirable. In this investigation, we tested the protective efficacy of BCG delivered in the neonatal period followed by boosters in the adult phase with a DNA vaccine containing the hsp65 gene from Mycobacterium leprae (pVAXhsp65). Immune responses were characterized by serum anti‐hsp65 antibody levels and IFN‐γ and IL‐5 production by the spleen. Amounts of these cytokines were also determined in lung homogenates. Protective efficacy was established by the number of colony‐forming units (CFU) and histopathological analysis of the lungs after challenge with Mycobacterium tuberculosis. Immunization with BCG alone triggered a significant reduction of CFU in the lungs and also clearly preserved the pulmonary parenchyma. BCG priming also increased the immunogenicity of pVAXhsp65. However, boosters with pVAXhsp65 or the empty vector abolished the protective efficacy of BCG. Also, higher IL‐5 levels were produced by spleen and lungs after DNA boosters. These results demonstrated that neonatal BCG immunization followed by DNAhsp65 boosters is highly immunogenic but is not protective against tuberculosis.
The “Coping” Capacity Management Strategy in Services and the Influence on Quality Performance

Matching supply and demand in services by capacity management has a direct influence on the ability of the service delivery system to achieve service quality and resource productivity targets. Examines some propositions for the influences of capacity management on quality and resource productivity and for managing capacity. In addition to the chase and level strategies for managing capacity in services suggested by Sasser a coping strategy for capacity management is described which aims to improve the overall delivery of service quality while achieving resource productivity targets. Coping is necessary for all organizations at some time. Some research results derived from the experience of a range of service organizations indicate a less than satisfactory handling of the coping situation.
Timing-accurate storage emulation: evaluating hypothetical storage components in real computer systems

Timing-accurate storage emulation offers a unique performance evaluation capability: the flexibility of simulation with the reality of experimental measurements. This allows a researcher to experiment with not-yet-existing storage components in the context of real systems executing real applications. As its name suggests, a timing-accurate storage emulator appears to the system to be a real storage component with service times matching a simulation model (or other computational model) of that component. This allows simulated storage components to be plugged into real systems, which can then be used for complete, application-based experimentation. Additionally, timing-accurate storage emulation offers the opportunity to investigate more expressive interfaces between storage and computer systems, permitting forays into the space of hypothetical device functionalities without the difficulties of developing and supporting extensively nonstandard or novel interface actions in prototype or production systems. This dissertation identifies that there is a current and pressing need for a new storage evaluation technique, discusses design issues for achieving accurate per-request service times in a timing-accurate storage emulator, and demonstrates that it is feasible to construct and use such an emulator for interesting system-level experimentation. We built a functional timing-accurate storage emulator and explored its use in experiments involving models of existing storage products, experiments evaluating the potential of nonexistent storage components, and experiments evaluating interactions between modified computer systems and expanded storage device functionality. To experiment with existing and hypothetical storage components in computer systems, we configured our emulator with device models representing a currently-available production disk drive, a hypothetical 50,000 RPM disk drive, and a hypothetical MEMS-based storage device, and executed three application-level workloads against these emulated models. To explore system architectures with expanded device functionality, we applied the principles of timing-accurate storage emulation in an investigation into storage-based intrusion detection systems. This experimentation demonstrates that our emulator accurately reflects the performance of modeled devices, demonstrates the feasibility of including intrusion detection capabilities into a standalone processing-enhanced disk drive, and demonstrates that extensions to existing storage communications paths may be used to transmit and receive information regarding the configuration and operational status of such an enhanced device.
In‐group preference as opportunism governance in a collectivist culture: evidence from Korean retail buyer‐supplier relationships

Purpose – The purpose of this paper is to examine whether preference toward in‐group members can serve as opportunism governance in channel relationships in a collectivist culture. This study proposes a model of opportunism incorporating in‐group preference and trust as antecedents of opportunism. Based on Transaction Cost Economics and Social Exchange Theory, transaction‐specific investment and relationship length are employed in the model as confounding variables of in‐group preference for opportunism and trust.Design/methodology/approach – Data were collected from 109 Korean department store buyers and analyzed using Structural Equation Modeling (EQS 6.0). Findings – The results showed that buyers' in‐group preference increased buyers' trust toward suppliers and decreased suppliers' opportunistic behavior. Buyers' increased trust toward suppliers was found to reduce suppliers' opportunistic behavior. Further, Trust was significantly influenced by supplier TSI, but not by length of relationship. On the o.
Governance Issues for SMEs

This paper draws on research into the corporate governance practices of small and medium enterprises (SMEs) listed on the Australian Securities Exchange. Interviews were conducted with the directors and/or company secretaries of 19 SMEs. The aim of the research was to explore not only SME corporate governance structures and processes but how SMEs had chosen to implement the Principles and the reasons for their choices. The paper addresses the issue of whether the ASX Corporate Governance Principles and Recommendations were appropriate for SMEs. It describes the SME responses to the requirements, how these differ from those of larger companies, and how these differences impact on small companies.
The Effect of Consumption Value on Attitude and Repurchase Intention of Secondhand Fashion Goods -The Moderating Role of Self-confidence in Fashion Coordination-

This study investigates the influence of consumption value on attitude and the repurchase intention of secondhand fashion goods. In addition, this study examines the effect of consumption value on attitudes according to self-confidence in fashion coordination. Questionnaire data from 220 university students who made purchases of secondhand fashion goods were analyzed. The results were as follows. First, there were 5 factor solutions for the consumption value of secondhand fashion good: rare value, emotional value, functional value, social contribution value, and economic value. Second, rare value, social contribution value and economic value had a positive impact on the attitude toward secondhand fashion goods. Third, attitude had positive impact on the repurchase intention of secondhand fashion goods. Fourth, there was a significant difference in the magnitude of the effect of consumption value on attitude according to self- confidence in fashion coordination. The results of this study provide various guidelines for marketers or retailers who are interested in secondhand fashion goods.
Differential expression of sphingolipids in MRP1 overexpressing HT29 cells

We have obtained a novel multidrug resistant cell line, derived from HT29 G+ human colon carcinoma cells, by selection with gradually increasing concentrations of the anti‐mitotic, microtubule‐disrupting agent colchicine. This HT29col cell line displayed a 25‐fold increase in colchicine resistance and exhibited cross‐resistance to doxorubicin, VP16, vincristine and taxol. Immunoblotting, combined with RT‐PCR showed that the multidrug resistance phenotype was conferred by specific overexpression of the multidrug resistance protein 1. Confocal scanning laser microscopy revealed that multidrug resistance protein 1 specifically localized in the plasma membrane of HT29col cells. In a functional assay, using the fluorescent multidrug resistance protein 1 substrate 5‐carboxyfluorescein, an increased efflux activity of HT29col cells was measured, as compared to the wild‐type HT29 G+ cells. MK571, a specific inhibitor of multidrug resistance protein 1, blocked the 5‐carboxyfluorescein efflux, but only partially reversed resistance to colchicine, indicating that additional multidrug resistance mechanisms operate in HT29col cells. In conclusion, these results show for the first time overexpression of a functional multidrug resistance protein 1 under colchicine pressure, indicating that colchicine is not a P‐glycoprotein‐specific substrate. Colchicine‐induced overexpression of multidrug resistance protein 1 is accompanied by a changed sphingolipid composition, i.e., enhanced levels of glucosylceramide and galactosylceramide. In addition, ceramide, a lipid messenger molecule involved in apoptosis‐related signal transduction processes, was much more abundant in HT29col cells, which is indicative of a stress response. Int. J. Cancer 87:172–178, 2000. © 2000 Wiley‐Liss, Inc.
Marketing, Scientific Progress, and Scientific Method

It is argued that the long debate concerning the scientific credentials of marketing has been couched in terms of an idealized notion of science as the ultimate source of objectively certified knowledge. A review of contemporary literature in the philosophy, sociology, and history of science reveals that this canonical conception of science cannot be supported. The implications of this literature for the marketing–as–science debate are developed, and practical measures for the enhancement of scientific practice in marketing are discussed.
Characterization of Binding of Streptococcus oralis Glyceraldehyde-3-Phosphate Dehydrogenase to Porphyromonas gingivalis Major Fimbriae

ABSTRACT Binding of Streptococcus oralis glyceraldehyde-3-phosphate dehydrogenase (GAPDH) to Porphyromonas gingivalis fimbriae was characterized via a biomolecular interaction analysis system. The interaction was specific, and the association constant value was 4.34 × 107 M−1, suggesting that S. oralis GAPDH functions as a dominant receptor for P. gingivalis and contributes to P. gingivalis colonization.
Trisomy 3q25.1‐qter and monosomy 8p23.1‐pter in a patient: Cytogenetic and molecular analysis with delineation of the phenotype

We describe a 4‐year‐old boy with partial 3q trisomy and distal 8p monosomy. The patient presented with mental retardation, dysmorphic face, congenital heart defect, brain and genital anomalies, and behavioral problems. The conventional cytogenetic analysis showed a 46,XY,add(8p) karyotype. Reverse painting and microsatellite analysis demonstrated a partial monosomy of 8p23.1 → pter and a partial trisomy of 3q25.1 → qter. The data suggest that the chromosomal rearrangement originated from a de novo translocation in a paternal germinal cell. The phenotype observed in our patient resulted from the combination of those defects described in the isolated dup(3q) and distal del(8p) syndromes. © 2005 Wiley‐Liss, Inc.
Recreating the Workplace: Leisure, Lifestyle and Work-Life Balance for Micro-business Tourist Accommodation Operators

Abstract This paper explores leisure, lifestyle and work-life balance for a group of business people working in the tourism industry through a qualitative study of the experiences of microbusiness accommodation operators. Thematic analysis was used to investigate the nature of leisure, lifestyle and work-life balance in the context of involvement, commercial success and sustainability. Results indicate that lifestyle is a key factor in decisionmaking,being constructed around the four themes of: people; way of life; work-life; and control. In the construction of lifestyle, leisure plays a role, but this is never defined and is interwoven throughout the everyday. This study suggests that combining work and leisure can be a dangerous activity, and that leisure needs to be nurtured if burnout is to be avoided. The study also suggests that leisure and work cannot truly be separated in such workplaces, and have a highly complex and interconnected relationship that deserves further study.
Proteomic analysis of outer membrane vesicles from the probiotic strain Escherichia coli Nissle 1917

Escherichia coli Nissle 1917 (EcN) is a probiotic used for the treatment of intestinal disorders. EcN improves gastrointestinal homeostasis and microbiota balance; however, little is known about how this probiotic delivers effector molecules to the host. Outer membrane vesicles (OMVs) are constitutively produced by Gram‐negative bacteria and have a relevant role in bacteria–host interactions. Using 1D SDS–PAGE and highly sensitive LC–MS/MS analysis we identified in this study 192 EcN vesicular proteins with high confidence in three independent biological replicates. Of these proteins, 18 were encoded by strain‐linked genes and 57 were common to pathogen‐derived OMVs. These proteins may contribute to the ability of this probiotic to colonize the human gut as they fulfil functions related to adhesion, immune modulation or bacterial survival in host niches. This study describes the first global OMV proteome of a probiotic strain and provides evidence that probiotic‐derived OMVs contain proteins that can target these vesicles to the host and mediate their beneficial effects on intestinal function. All MS data have been deposited in the ProteomeXchange with identifier PXD000367 (http://proteomecentral.proteomexchange.org/dataset/PXD000367).
Stochastic Parameterization: Towards a new view of Weather and Climate Models

AbstractThe last decade has seen the success of stochastic parameterizations in short-term, medium-range, and seasonal forecasts: operational weather centers now routinely use stochastic parameterization schemes to represent model inadequacy better and to improve the quantification of forecast uncertainty. Developed initially for numerical weather prediction, the inclusion of stochastic parameterizations not only provides better estimates of uncertainty, but it is also extremely promising for reducing long-standing climate biases and is relevant for determining the climate response to external forcing. This article highlights recent developments from different research groups that show that the stochastic representation of unresolved processes in the atmosphere, oceans, land surface, and cryosphere of comprehensive weather and climate models 1) gives rise to more reliable probabilistic forecasts of weather and climate and 2) reduces systematic model bias. We make a case that the use of mathematically stri.
A novel direct power control strategy based on energy interface concept for three-level PWM rectifier

This paper investigates the energy interfaces in three-level pulse width modulation (PWM) rectifier and proposes a novel direct power control (DPC) strategy. An optimized three-level switching table with high power regulation intensities is constructed in order to improve the tracking capabilities of power loops. An energy regulator is designed based on the power equations of the energy interfaces to control the energy stored in the dc-link capacitors and to maintain the required output voltage. Compared with the conventional three-level DPC, the novel strategy achieves better performances. Simulation and experimental results have verified the validity and feasibility of the proposed method.
Accounting Issues in Electronic Commerce: An USA Perspective Regarding Valuations and Implications for Corporate Governance

The proliferation of dot-coms in the mid-tolate 1990s and the rapid deployment of ecommerce created both challenges and opportunities for the accounting profession. The failure of the profession to adequately react may have been the precursor to the Sarbanes-Oxley Act, which addressed valuation and corporate governance issues. This paper addresses issues that affected the areas of accounting and reporting, dubious and misleading practices by some firms, and consulting practice in ecommerce and operations. The nature of dot-com firms presents the need for new approaches to valuation, a review of questionable practices, new metrics to provide information, an examination of the subjective aspects of valuation and the integration of valuation with strategy formation.
Understanding attributional biases, emotions and self-esteem in 'poor me' paranoia: findings from an early psychosis sample.

OBJECTIVES Trower and Chadwick's (1995) theory of two types of paranoia ('poor me' and 'bad me') provides a framework for understanding the seemingly contradictory evidence on persecutory delusions. Paranoia has been argued to defend against low self-esteem, but people with persecutory delusions report high levels of emotional distress and, in some instances, low self-worth. The current study investigates attributions and emotions in a sample of people with early psychosis who have persecutory delusions. 'Poor me' paranoia has been found to be more frequent than 'bad me' paranoia in the early stages of psychosis. Anger and a tendency to blame other people are hypothesized to characterize 'poor me' paranoia. DESIGN AND METHODS The study had a cross-sectional design. Twenty individuals with early psychosis, 21 clinical controls with depression and 32 healthy volunteers completed a thorough assessment of emotions and attributions. RESULTS The 'poor me' paranoia group showed higher levels of anger, anxiety and depression than the non-clinical control group. Self-esteem and guilt were however preserved. A tendency to blame others but not themselves was characteristic of the 'poor me' paranoia group whereas people in the clinical control group tended to self-blame for failures. Anger, but not self-esteem, was associated with an attributional bias characterized by blaming other people instead of oneself. CONCLUSIONS In conclusion, anger, a previously overlooked emotion in the study of persecutory delusions, warrants further attention. The other-directed nature of this emotion highlights the potential role of interpersonal schemas in understanding paranoia.
A modified AdaBoost method for one-class SVM and its application to novelty detection

One-Class Support Vector Machine (OCSVM) is a general approach for novelty detection in the fields of machine learning and pattern classification. At the same time, AdaBoost is a famous ensemble method which can improve the performance of its base classifiers. However, the base classifiers in the AdaBoost method prefer to be weak classifiers. Since OCSVM is regarded as a strong classifier, the traditional AdaBoost method may not improve the classification performance of OCSVM. Therefore, to construct the AdaBoost method for OCSVM, we modify the traditional AdaBoost method to make it fit for OCSVM. Experimental results on three synthetic data sets and eight UCI benchmark data sets demonstrate that the proposed method is superior to its related methods.
Cytokine gene polymorphism in recurrent acute otitis media.

BACKGROUND There is increasing evidence that a strong genetic component is involved in the predisposition to recurrent acute otitis media (rAOM). Cytokines play a key role in the pathogenesis of otitis media. Constitutional polymorphisms in cytokine genes may lead to individual variations in cytokine secretion. OBJECTIVE To elucidate the role of cytokine gene polymorphisms in rAOM. SETTING University hospital. PARTICIPANTS AND METHODS Blood samples for genetic analysis were obtained from 63 individuals with rAOM from 20 different families and from 400 healthy blood donors. The medical history of the rAOM group was based on medical records and interview data. We studied the polymorphisms of tumor necrosis factor alpha, interleukin (IL) 1 alpha, IL-1 beta, and IL-1 receptor antagonist genes. RESULTS The distribution of cytokine alleles in the rAOM group did not differ significantly from that of the control group. However, in patients with rAOM without a history of allergic disorders, allele frequencies of IL-1 alpha-889 differed significantly from those of controls (P =.03). CONCLUSIONS There is no clear association between the polymorphism of studied cytokine genes and rAOM. However, the IL-1 alpha gene polymorphism may be associated with recurrent middle ear infections in a subgroup of patients without allergic disorders.