Miracle-dz/UniFAR-FTUs huggingface dataset:
Evolutionary genetic relationships of clones of Salmonella serovars that cause human typhoid and other enteric fevers

Multilocus enzyme electrophoresis was employed to measure chromosomal genotypic diversity and evolutionary relationships among 761 isolates of the serovars Salmonella typhi, S. paratyphi A, S. paratyphi B, S. paratyphi C, and S. sendai, which are human-adapted agents of enteric fever, and S. miami and S. java, which are serotypically similar to S. sendai and S. paratyphi B, respectively, but cause gastroenteritis in both humans and animals. To determine the phylogenetic positions of the clones of these forms within the context of the salmonellae of subspecies I, comparative data for 22 other common serovars were utilized. Except for S. paratyphi A and S. sendai, the analysis revealed no close phylogenetic relationships among clones of different human-adapted serovars, which implies convergence in host adaptation and virulence factors. Clones of S. miami are not allied with those of S. sendai or S. paratyphi A, being, instead, closely related to strains of S. panama. Clones of S. paratyphi B and S. java belong to a large phylogenetic complex that includes clones of S. typhimurium, S. heidelberg, S. saintpaul, and S. muenchen. Most strains of S. paratyphi B belong to a globally distributed clone that is highly polymorphic in biotype, bacteriophage type, and several other characters, whereas strains of S. java represent seven diverse lineages. The flagellar monophasic forms of S. java are genotypically more similar to clones of S. typhimurium than to other clones of S. java or S. paratyphi B. Clones of S. paratyphi C are related to those of S. choleraesuis. DNA probing with a segment of the viaB region specific for the Vi capsular antigen genes indicated that the frequent failure of isolates of S. paratyphi C to express Vi antigen is almost entirely attributable to regulatory processes rather than to an absence of the structural determinant genes themselves. Two clones of S. typhisuis are related to those of S. choleraesuis and S. paratyphi C, but a third clone is not. Although the clones of S. decatur and S. choleraesuis are serologically and biochemically similar, they are genotypically very distinct. Two clones of S. typhi were distinguished, one globally distributed and another apparently confined to Africa; both clones are distantly related to those of all other serovars studied.
Possible Protective Effect of Vitamin E on The Joined Cardio-Renal Effects of Lead Toxicity and Noise Stress in Rats

Pollution is a worldwide problem and its potential to influence the physiological systems of human population is great. Many studies found that some pollutants have detrimental effects on human growth, particularly prenatal growth. Lead is one of the heavy metals commonly found in human populations. Lead toxicity was reported to be related to haemopoietic, hepatic, renal, nervous, gastrointestinal and reproductive disorders in man and animals. Recent studies have reported lead's potential for inducing oxidative stress which plays a role in the pathophysiology of lead toxicity. Noise stress from transportation sources also is related to different physiological effects on human, as well as impairment of auditory function and growth. Studies showed that combined exposure to noise and different pollutants affects heart and other organs. On the other hand, antioxidants were reported to reduce incidence to various physiological alterations accompanied by oxidative stress. Previous studies suggested that antioxidants may play an important role in abating some hazards of lead. The aim of the present work was to evaluate the possible ameliorating effect of vitamin E, as an antioxidant, on some alterations caused by lead or noise alone or in combination on kidney and heart biomarkers in adult male rats. Vitamin E was administered orally in a dose of 200 mg/kg two hours before lead dosage (15 mg/kg, i.p). Animals were exposed to horn noise of about 110 dB for 30 minutes after administration of lead and/or vitamin E. The experiment was conducted for 14 consecutive days. The evaluated parameters included assessment of serum levels of urea, creatinine, Aspartate aminotransferase (AST), creatine kinase (CK) and lactate dehydrogenase (LDH) and levels of reduced glutathione (GSH) and malondialdehyde (MDA) in kidney and heart tissues. The histolopathological changes in both kidney and heart were reported. The obtained results revealed that lead and noise either alone or in combination caused statistically changes in the examined parameters with a good potential for vitamin E to protect against these changes.
Getting Started with Quantitative Methods in Physics Education Research

In this article we provide a brief overview of three groups of quantitative research methods commonly used in physics education research (PER): descriptive statistics, inferential statistics, and measurement instrument development and validation. These quantitative research methods are used respectively in three major types of PER, namely survey research, experimental/quasi-experimental studies, and measurement and evaluation studies. In order to highlight the importance of the close alignment between research questions and selected quantitative research methods, we review these quantitative techniques within each research type from three perspectives: data collection, data analysis, and result interpretation. We discuss the purpose, key aspects and potential issues of each quantitative technique, and where possible, specific PER studies are included as examples to illustrate how these methods fulfill specific research goals. Getting Started in PER 1 Ding and Liu Quantitative Methods in PER
Searching for Blind Geothermal Systems Utilizing Play Fairway Analysis , Western Nevada

34 GRC Bulletin l www.geothermal. org Background Geothermal play fairway analysis is a concept adopted from the oil industry aimed at improving the efficiency and success rate of geothermal exploration and drilling. It involves integration of multiple geologic and geophysical parameters indicative of geothermal activity as a means of identifying the most promising areas for new geothermal development. This includes the evaluation of the relative favorability of known, undeveloped geothermal systems, as well as assessing the probability of a particular area for hosting a relatively robust blind system (>~130C). Blind systems lack surface hot springs and steam vents and are thought to comprise the majority of geothermal systems in the Great Basin region. James E. Faulds Jason W. Craig , Mark F. Coolbaugh, Nicholas H. Hinz, Jonathan M. Glen, and Stephen Deoreo Nevada Bureau of Mines and Geology, University of Nevada, Reno, NV 89557 U.S. Geological Survey, Menlo Park, CA 94025
Board-Level Drop Test : Comparison of Two ANSYS Modeling Approaches and Correlation with Testing

Two ANSYS-based transient analysis approaches for simulating the board-level drop test of an electronic packaging assembly and correlation with measured responses are described. The procedures for the two finite element approaches, the Large Mass Method and the Direct Acceleration Input method, are discussed. Additionally, a method for including damping estimation for numerical transient analysis, based on measured data, is presented. Both modeling analysis techniques provide reasonable correlation to the test data, however, the large mass method more closely mimics the initial acceleration response as observed in the measurements and it is therefore the recommend approach within ANSYS.
The Diagnostic Predictive Value of R wave peak time in Patients with Acute Pulmonary Embolism

This study aimed to investigate the diagnostic predictive value of R wave peak time (RWPT) in patients admitted to the emergency department with a preliminary diagnosis of acute pulmonary embolism (APE). Computerized tomographic pulmonary angiography (CTPA) was performed in 74 consecutive patients with suspected APE, and of these 66 patients with appropriate electrocardiogram (ECG) and CTPA images composed the study population.By using CTPA, APE was confirmed in 27 patients. While the atrial arrhythmia, right axis deviation, complete or incomplete right bundle branch block, prominent S wave in the lead DI, S1Q3T3 pattern, and RWPT in the lead DIII (40±11 vs. 31±13 ms) were statistically different in patients with APE compared to those without APE (p<0.05, for all), the other ECG findings were similar. Multivariate analysis revealed that RWPT in the lead DIII (odds ratio: 14.959, 95% confidence interval: 1.811–123.582, p=0.012) was found to be an independent predictor of APE. A receiver operating characteristic analysis was drawn to show the best cut-off value of the RWPT in the lead DIII to predict APE was ≥40 ms with 48.1% sensitivity and 87.2 % specificity (area under curve (AUC): 0.718; 95% CI: 0.593–0.843; p=0.003). The present study demonstrated that the RWPT in the lead DIII may have diagnostic predictive value for APE. In addition, it may be useful in electrocardiographic signs for the diagnosis of APE.
Effects of Cryo-Milling and Milling Time on the Microstructures of Oxide-Dispersion Strengthened CoCrFeMnNi High-Entropy Alloy Powder

High Entropy Alloys (HEAs) have more than 5 metallic principal elements with an equiatomic ratio or near equiatomic ratio [1]. HEAs exhibit excellent mechanical properties [3, 4] due to the following characteristics: High configurational entropy, lattice distortion, sluggish diffusion and cocktail effect [2]. Therefore HEAs appear to be a promising material for applications which require the excellent mechanical properties. Despite the excellent mechanical properties of HEAs, improving HEAs is inevitable to expand the utilization areas of HEAs. Especially, the irradiation performance of HEAs is not established clearly yet [5]. To maintain the structural and compositional stability under irradiation, dispersing the nano-sized oxide particles in HEAs has been considered [5-7]. The oxide-dispersion strengthened steels (ODSs) are usually manufactured by the complicated process. Mechanical alloying (MA) is usually using for fabricating the ODS to disperse the nano-sized oxide particles homogeneously and make the size of particles very fine [8]. The mechanically alloyed powder subsequently consolidated by hot isostatic pressing (HIP) or spark plasma sintering (SPS) to obtain fully dense material in the required shape and promote the forming of nano-sized oxide particles within the matrix. However, the MA process has some drawbacks such as the timeand cost-consuming process, contamination from milling media, oxidation due to the friction heat during the MA [9]. CoCrFeMnNi HEA, which is called as Cantor alloy, is generally known as a model HEA. It shows a single phase with a simple FCC structure and exhibits both excellent ductility and fracture toughness even at a cryogenic temperature [10]. To understand the oxide dispersion strengthening mechanism of the HEA matrix, CoCrFeMnNi FCC HEA was chosen for this study. In the present study, to clarify the milling parameters such as milling time and milling temperature, cryomilling is selected as a method of MA. Microstructural characterization is conducted to understand the forming mechanisms of the nano-sized oxide particles at the powder preparing stage.
Decision-Theoretic Planning with Fuzzy Notions in GOLOG

In this paper we present an extension of the action language Golog that allows for using fuzzy notions in non-deterministic argument choices and the reward function in decision-theoretic planning. Often, in decision-theoretic planning, it is cumbersome to specify the set of values to pick from in the non-deterministic-choice-of-argument statement. Also, even for domain experts, it is not always easy to specify a reward function. Instead of providing a finite domain for values in the non-deterministic-choice-of-argument statement in Golog, we now allow for stating the argument domain by simply providing a formula over linguistic terms and fuzzy uents. In Golog’s forward-search DT planning algorithm, these formulas are evaluated in order to find the agent’s optimal policy. We illustrate this in the Diner Domain where the agent needs to calculate the optimal serving order.
Protein Kinase C Regulates the Interaction between a GABA Transporter and Syntaxin 1A

Syntaxin 1A inhibits GABA uptake of an endogenous GABA transporter in neuronal cultures from rat hippocampus and in reconstitution systems expressing the cloned rat brain GABA transporter GAT1. Evidence of interactions between syntaxin 1A and GAT1 comes from three experimental approaches: botulinum toxin cleavage of syntaxin 1A, syntaxin 1A antisense treatments, and coimmunoprecipitation of a complex containing GAT1 and syntaxin 1A. Protein kinase C (PKC), shown previously to modulate GABA transporter function, exerts its modulatory effects by regulating the availability of syntaxin 1A to interact with the transporter, and a transporter mutant that fails to interact with syntaxin 1A is not regulated by PKC. These results suggest a new target for regulation by syntaxin 1A and a novel mechanism for controlling the machinery involved in both neurotransmitter release and reuptake.
A Packaging Solution for Optically Testing Wire-Bonded Chips

In this paper, we describe the design and the experimental characterization of a packaging technique for backside optical testing of chips requiring wirebonding. Optical testing methods, based either on the collection of spontaneous hot-carrier photoemission or on laser stimulation, require an optical access to the active area of the circuit through the backside of the chip, while still providing mechanical support to the thinned die (very fragile), heat sinking capability, power and electrical signals. The proposed package fulfils all these requirements and it can hence be used for picosecond imaging for circuit analysis/time resolved emission measurements, emission microscopy investigations, laser voltage probe, thermal laser stimulation, photoelectric laser stimulation, and other failure analysis methods that require optical access to the transistor level through the silicon backside. The advantages of the new package are its versatility (it can fit different chip sizes), easy handling, low cost, and the fact that it is designed for optical testing and not just for electrical testing. We successfully used the proposed package for optically test chips in advanced complementary metal-oxide-semiconductor technologies (65 nm): measurements at low voltage are possible thanks to the proposed package.
How did the implementation of the innovation processes to influence the business environment guarantee the success of the internationalization process : Cases of Moroccan mining companies .

The business environment is becoming increasingly globalized and complex. Our study relates to: how can a company install environment effect processes to support its in-house built innovation capability. Instances of SME in the Moroccan mining sector were studied to work out a model of integrated approach of business environment effect to support the company’s innovation capability.
Removing Bottlenecks in Big Data Processing Platforms

Emerging Big Data analytics applications require a significant amount of computational power. As the demand for computational resources continues to grow, analytical needs for Big Data can be satisfied with high performance computing models. Additionally, High Performance Computing (HPC) has evolved over the years to meet the ever-increasing demands for processing speed. While some data-intensive applications are intended to be executed on commodity hardware in a “scale out” architecture, there are certain situations in which ultra-fast, highcapacity HPC “scale up” approaches are preferred. Current Big Data processing platforms like Hadoop and Spark which use the Java Virtual Machine (JVM) as an execution environment are abstracting away the architecture and lowlevel properties of modern systems. This can become a potential bottleneck in large-scale applications and prevent many systemand network-related optimizations. Therefore, the aim of my research is to investigate the performance liabilities of existing large scale data processing frameworks compared to HPC and offer system-aware and efficient solutions.
A G ] 2 5 A pr 2 01 9 Tropical Combinatorial Nullstellensatz and Sparse Polynomials ∗

Tropical algebra emerges in many fields of mathematics such as algebraic geometry, mathematical physics and combinatorial optimization. In part, its importance is related to the fact that it makes various parameters of mathematical objects computationally accessible. Tropical polynomials play a fundamental role in this, especially for the case of algebraic geometry. On the other hand, many algebraic questions behind tropical polynomials remain open. In this paper we address four basic questions on tropical polynomials closely related to their computational properties: 1. Given a polynomial with a certain support (set of monomials) and a (finite) set of inputs, when is it possible for the polynomial to vanish on all these inputs? 2. A more precise question, given a polynomial with a certain support and a (finite) set of inputs, how many roots can this polynomial have on this set of inputs? 3. Given an integer k, for which s there is a set of s inputs such that any non-zero polynomial with at most k monomials has a non-root among these inputs? ∗An extended abstract of a preliminary version [17] appeared in the proceedings of the 21st International Symposium on Fundamentals of Computation Theory (FCT 2017). The results of Sections 4 and 6 were obtained by the first author at MCCME and supported by the Russian Science Foundation (project 16-11-10075). The results of Sections 3 and 5 were obtained by the second author and were supported by grant MK-5379.2018. 1, by the Russian Academic Excellence Project ‘5-100’ and by RFBR grant 17-51-10005-KO_a.
Load Balancing Via Inter-Frequency Handovers In LTE Networks

The main scope of this work was to develop and study the performance of a load balancing mechanism using interfrequency handovers in LTE networks that contemplate the deployment of different co-located frequency bands, specifically the 800, 1800 and 2600 MHz frequency bands, in an urban scenario. Three different situations were taken into account by pairing the three frequency bands and assigning a higher priority to the higher carrier frequencies. The main parameters under study were network load, number of active users and their respective received power, number of allocated resources and throughput. Generated users requested typical data or Voice over LTE (VoLTE) services and they were associated to a sector according to their received power to better represent a real network. Studies were made considering a high and a low load scenarios and measurements were performed over the city of Lisbon, also for analysis. The algorithm was implemented under the form of a simulator and it is found that it is more efficient in scenarios with higher user density, seeing as an average of 520 users are served with throughputs that achieve 2.5 Mbps and 1.5 Mbps using the combination of the 1800 MHz band with the 2600 or with the 800 MHz band respectively, while maintaining network load stabilised on 90%. KeywordsLTE, load balancing, inter-frequency handovers, colocated frequency band, Lisbon
PELVIC URINE CULTURE AND SENSITIVITY ARE BETTER THAN BLADDER URINE AS PREDICTORS OF UROSEPSIS FOLLOWING PERCUTANEOUS NEPHROLITHOTOMY : A PROSPECTIVE CLINICAL STUDY

Purpose: Urosepsis due to manipulation during percutaneous nephrolithotomy (PCNL) can be catastrophic despite prophylactic antibiotic coverage, and negative midstream urine culture and sensitivity testing (C&S). It has been postulated that bacteria in the stone may be responsible for systemic infection. In this prospective study we determined the correlation between different sites of urine sampling, including stones, and also ascertained which is more predictive of urosepsis. Material and Methods: All patients undergoing PCNL who fulfilled our selection criteria were recruited. The samples collected were 1) midstream urine and bladder urine at cystoscopy, 2) renal pelvic urine collected at percutaneous puncture of the pelvicaliceal system and 3) extracted and later fragmented stones. They were sent immediately for C&S. Patients were monitored for systemic inflammatory response syndrome (SIRS). Results: A total of 54 procedures were suitable for analysis. Midstream urine C&S was positive in 11.1% of cases, stone C&S was positive in 35.2% and pelvic C&S was positive in 20.4% (p 0.009). Pelvic urine C&S predicted infected stones better than bladder urine C&S. Of the patients 37% had SIRS and 3 experienced septic shock. Patients with infected stones or pelvic urine were found to be at a relative risk for urosepsis that was at least 4 times greater (p 0.0009). Bladder urine did not predict SIRS. Stone C&S had the highest positive predictive value of 0.7. Preoperative hydronephrosis correlated with infected pelvic urine. No patients with urosepsis had positive blood C&S. Conclusions: The results of this study suggest that positive stone C&S and pelvic urine C&S are better predictors of potential urosepsis than bladder urine. Therefore, routine collection of these specimens is recommended.
Accounting for the future : Psychological aspects of effectual entrepreneurship

Recent attempts to study entrepreneurship as a form of expertise, rather than a collection of traits and abilities have led to the development of the theory of effectuation. Effectuation is a sequence of non-predictive strategies in dynamic problem-solving that is primarily meansdriven, where goals emerge as a consequence of stakeholder commitments rather than vice versa. Most important, effectuation isolates, identifies, and exploits techniques that seek to control the future without having to predict it. In this paper we (1) bring effectuation to psychology; (2) develop it further by examining key behavioral constructs that make effectual action possible; and, (3) derive possible implications for future research in psychology, particularly in relation to a more pluralistic understanding of human rationality.
Synergistic High-performance Work System and Perceived Organizational performance of Small and Medium-Sized Enterprises : A Review of Literature and Proposed Research Model

High performance work systems (HPWS) are found as an effective driver of organizational performance in several studies. Nevertheless, most of previous studies of HPWS were conducted with a simple set of HR practices and there is a lack of strategic approach for HPWS as a truly synergistic system (Banks & Kepes, 2015; Lengnick-Hall, Lengnick-Hall, Andrade, & Drake, 2009). Especially, the previous studies were mainly addressed in the context of large business and it is far from clearance in SME context. Thus, this paper attempts to bridge the gaps by exploring the nature of HPWS from strategic and systematic approach as well as identifying the the potential effect of synergistic HPWS on perceived organizational performance. Under the light of strategic management, HPWS is explored with necessary dimensions to sustain the nature as well as effectiveness of a system. Hence, this study enriches the cross-field literature of strategic management and HRM. The proposed research model and proposition of the relationship between synergistic HPWS and organizational performance contribute to development of strategic HRM literature and the theoretical groundwork for further empirical studies of HPWS.