Miracle-dz/UniFAR-FTUs huggingface dataset:
Potentiality and Boundaries of Use of Sorafenib in Patients with Hepatocellular Carcinoma: Awaiting the Results of Ongoing Clinical Trials

No systemic therapy had been proven effective in patients with advanced hepatocellular carcinoma (HCC) until 2007, when a large randomized trial with sorafenib demonstrated a clinically relevant prolongation of survival. Currently, sorafenib represents standard treatment for patients with advanced HCC and well-preserved liver function, whilst the evidence about its effectiveness in patients with more severe liver impairment is less robust. A randomized trial to demonstrate the efficacy of sorafenib in Child-Pugh B patients with advanced HCC is currently ongoing. In the meantime, several trials are testing the role of sorafenib in early HCC (as adjuvant treatment after potentially curative loco-regional therapies) and in intermediate stage (exploring different modalities of integration of sorafenib with trans-arterial chemo-embolization). The results of all these trials will better define the potentiality and the boundaries of use of sorafenib in HCC patients.
Trends in the Development of Machinery and Associated Technology ” TMT 2011 , Prague , Czech Republic , 12-18 September 2011 PRODUCTION OF Fe-CCu POWDER COATINGS BY PULSE MAGNETIC PRESSING AND INFILTRATION

The present paper describes an application magnetic pulsed compaction of powders (MPCP) for laying coatings made of Fe-C-Cu powder. It is shown that MPCP process can be used for joining metallic parts with coatings made of Fe-C-Cu powder, where powder coating may act as an antifriction material on the surface of solid metallic part. Some perspective applications of MPCP process have been reported.
Paternal involvement as related to maternal employment and attachment behavior directed to the father by the one-year-old infant /

3. When a map, drawing or chart, etc., was part of the material being photographed the photographer followed a definite method in "sectioning" the material. It is customary to begin photoing at the upper left hand corner of a large sheet and to continue photoing from left to right in equal sections with a small overlap. If necessary, sectioning is continued again beginning below the first row and continuing on until complete.
A new ECG-based Automated External Defibrillator system

Automated External Defibrillators (AED) are basic portable defibrillators that are designed for minimally-trained or untrained non-medical personnel. A microprocessor inside the defibrillation automatically analyzes the patient's heart rhythm and advises the operator whether a shock is needed. Audible and visual prompts will guide the user through the process. AED would advise a shock only to ventricular fibrillation. In this paper, we will present a framework of AED system. There are two crucial components should be elaborately designed, the hardware system and the algorithm of detecting ventricular fibrillation. In this paper, we will present the design of hardware system and a new algorithm which could discriminate ventricular fibrillation (VF) from other unshockable rhythm through the measurement of Sample Entropy (SampEn). We compared the sensitivity, specificity, positive prediction, accuracy of the new algorithm with several earlier VF detection algorithms. The experimental results prove that the new algorithm can be well suited for short data sequences analysis, and reaches an elegant balance between detection time and accuracy.
Flow during Individual and Co-operative Gameplay

This study aims to further research in the field of video games by examining flow during individual and co-operative gameplay. Using a puzzle game called Droppit, we examined differences in flow based on two modes of play: single player vs. co-operative gameplay. Co-operative gameplay was found to induce greater flow in participants than single player gameplay. Additionally, co-operative gameplay participants had increased feelings of Challenge-Skill Balance, Unambiguous Feedback, Transformation of Time and Autotelic Experience. Our findings suggest that co-operative gameplay, involving puzzle-based problems, may result in increased flow during video game play.
The study of validity and reliability of the perceived value scale of prospective teachers in terms of teaching profession

The aim of this study was to develop "Perceived Value Scale in regard to Teaching Profession of Prospective Teachers ". The validity and reliability analysis of the scale, developed for prospective elementary school teachers, was performed. In order to determine the values of the teaching profession, first of all, the related literature was scanned and an essay about the values related to the profession was written by the elementary school teachers and prospective teachers. In this way, 75 values in regard to teaching profession were determined. The obtained values were asked to be ranked according to their significance by primary school teachers and prospective teachers and a likert scale consisting of 64 items was prepared for 10 values that are most significant. After receiving expert opinions on scale items, 491 prospective teachers were applied and analysis was performed with findings . According to the analysis results, the Kaiser-Meyer Olkin (KMO) sample suitability was found as 0.847. In order to determine the reliability of the scale, Cronbach Alpha internal consistency indexes were calculated. The internal consistency index (Cronbach Alpha) of the scale was found as 0.899. Varimax vertical rotation method was used to determine independent sub factors of the scale. The lower cut-off point of the factor loads is taken as 0.45. It was found that the scale consisting of 8 factors and 40 items, explained 58,674% of the total variance. Findings suggest that the "Perceived Value Scale in regard to Teaching Profession of Prospective Teachers” is a valid and reliable measurement tool that can be used to determine the perceived value of the teaching profession of primary school prospective teachers. Key words: Professional value, prospective teachers, teaching profession, teacher training.
Hazardous Rated Electrical Equipment and the Arc Flash Hazard

This paper evaluates the relationship between Hazardous Rated Electrical Equipment; equipment which is suitable for installation in Class I, Division 1 (Zone 1) or Division 2 (Zone 2) locations, and Arc Rated Switchgear; equipment designed to withstand the effects of an internal arcing fault. Using UL 1203 (Explosion-Proof and Dust-Ignition-Proof Electrical Equipment for use in Hazardous (Classified) Locations), IEEE C37.20. 7 (IEEE Guide for Testing Metal Enclosed Switchgear Rated Up to 38 kV for Internal Arcing Faults), and the Ralph H. Lee paper titled “Pressure Developed by Arcs”, this paper will explore the applicability of Hazardous Rated Equipment in the protection of personnel from an Arc Flash Hazard.
Enterprise resource planning: business needs and technologies

Presents briefly ERP as a software solution integrating various functional spheres in an organization. Highlights its role in building a customer process, ERP technologies, available systems, viz. database systems, communication protocols and user interface framework. Details organizational preparedness for embarking and evaluating the investment on ERP. Discusses its application, selection criteria for small and medium organizations and a case study in Indian context. Concludes that ERP is the tool for an integrated information system to stay competitive and customer‐oriented for all organizations.
VERI CATION OF A HUMAN IN THE LOOP OR IDENTI CATION VIA THE TURING TEST

We propose using a \Turing Test" in order to verify that a human is the one making a query to a service over the web. Thus, before a request is processed the user should answer as a challenge an instance of a problem chosen so that it is easy for humans to solve but the best known programs fail on a non-negligible fraction of the instances. We discuss several scenarios where such tests are desired and several potential sources for problems instances. We also dicuss the application of this idea for combatting junk mail.
Antihyperalgesic and Side Effects of Intrathecal Clonidine and Tizanidine in a Rat Model of Neuropathic Pain

Background Although intrathecal clonidine produces pronounced analgesia, antinociceptive doses of intrathecal clonidine produce several side effects, including hypotension, bradycardia, and sedation. Intrathecal tizanidine, another &agr;2-adrenergic agonist, has provided antinociception without producing pronounced hemodynamic changes in animal studies. However, it has been unclear whether antihyperalgesic doses of intrathecal clonidine and tizanidine produce hypotension and bradycardia in a neuropathic pain state. This study was designed to evaluate the antihyperalgesic effects and side effects of intrathecal clonidine and tizanidine in a rat model of neuropathic pain. Methods Male Sprague-Dawley rats were chronically implanted with lumbar intrathecal catheters, and the sciatic nerve was loosely ligated. After 21–28 days after surgery, the rats received intrathecal clonidine (0.3, 1.0, and 3.0 &mgr;g) and tizanidine (1.0, 2.0, and 5.0 &mgr;g), and the antihyperalgesic effects of thermal and mechanical stimuli were examined. In addition, the changes in blood pressure and heart rate, sedation level, and other side effects after intrathecal administration of drugs were recorded. Results The administration of 3.0 &mgr;g intrathecal clonidine or 5.0 &mgr;g tizanidine significantly reversed both thermal and mechanical hyperalgesia. The administration of 3.0 &mgr;g intrathecal clonidine, but not 5.0 &mgr;g tizanidine, significantly decreased mean blood pressure and heart rate and produced urinary voiding. A greater sedative effect was produced by 3.0 &mgr;g intrathecal clonidine than by 5.0 &mgr;g tizanidine. Conclusion The antihyperalgesic dose of intrathecal clonidine and the antinociceptive doses produced several side effects. Intrathecal tizanidine at the dose that reversed hyperalgesia would be preferable for neuropathic pain management because of absence of hypotension and bradycardia and lower incidence of sedation.
An analysis of regularization by diffusion for ill-posed Poisson likelihood estimations

The noise contained in images collected by a charge coupled device (CCD) camera is predominantly of Poisson type. This motivates the use of the negative-log Poisson likelihood function in place of the least-squares fit-to-data function. However, if the underlying mathematical model is assumed to have the form z = Au + γ, where z is the data and A is a compact operator and γ is the background light intensity, minimizing the negative-log Poisson likelihood function is an ill-posed problem, and hence some form of regularization is required. In previous work, the authors have performed theoretical analyses of two approaches for regularization in this setting: standard Tikhonov and total variation regularization. In this article, we consider a class of regularization functionals defined by differential operators of diffusion type, and our main results constitute a theoretical justification of this approach. However, in order to demonstrate that the approach is effective in practice, we follow our theoretical analysis with a numerical experiment.
Shift-map Image Registration

Shift-map image processing is a new framework based on energy minimization over a large space of labels. The optimization utilizes alpha-expansion moves and iterative refinement over a Gaussian pyramid. In this paper we extend the range of applications to image registration. To do this, new data and smoothness terms have to be constructed. We note a great improvement when we measure pixel similarities with the dense DAISY descriptor. The main contributions of this paper are: * The extension of the shift-map framework to include image registration. We register images for which SIFT only provides 3 correct matches. * A publicly available implementation of shift-map image processing (e.g. in painting, registration). We conclude by comparing shift-map registration to a recent method for optical flow with favorable results.
Parallel distributed compensation for Takagi-Sugeno fuzzy models: multiobjective controller design

Discusses multiobjective controller synthesis for the fuzzy Takagi-Sugeno model. Various performance specifications are included. Both the state-feedback controller and the dynamic feedback controller are presented. They are in the format of a parallel distributed compensation controller which is essentially a nonlinear controller. The controller synthesis is formulated as an LMI problem. The approach in the paper can also be applied to hybrid or switching systems.
An AI Planning-based Tool for Scheduling Satellite Nominal Operations

Satellite domains are becoming a fashionable area of research within the AI community due to the complexity of the problems that satellite domains need to solve. With the current U.S. and European focus on launching satellites for communication, broadcasting, or localization tasks, among others, the automatic control of these machines becomes an important problem. Many new techniques in both the planning and scheduling fields have been applied successfully, but still much work is left to be done for reliable autonomous architectures. The purpose of this article is to present CONSAT, a real application that plans and schedules the performance of nominal operations in four satellites during the course of a year for a commercial Spanish satellite company, HISPASAT. For this task, we have used an AI domain-independent planner that solves the planning and scheduling problems in the HISPASAT domain thanks to its capability of representing and handling continuous variables, coding functions to obtain the operators' variable values, and the use of control rules to prune the search. We also abstract the approach in order to generalize it to other domains that need an integrated approach to planning and scheduling.
Discovering task-oriented usage pattern for web recommendation

Web transaction data usually convey user task-oriented behaviour pattern. Web usage mining technique is able to capture such informative knowledge about user task pattern from usage data. With the discovered usage pattern information, it is possible to recommend Web user more preferred content or customized presentation according to the derived task preference. In this paper, we propose a Web recommendation framework based on discovering task-oriented usage pattern with Probabilistic Latent Semantic Analysis (PLSA) model. The user intended tasks are characterized by the latent factors through probabilistic inference, to represent the user navigational interests. Moreover, the active user's intuitive task-oriented preference is quantized by the probabilities, by which pages visited in current user session are associated with various tasks as well. Combining the identified task preference of current user with the discovered usage-based Web page categories, we can present user more potentially interested or preferred Web content. The preliminary experiments performed on real world data sets demonstrate the usability and effectiveness of the proposed approach.
Towards an understanding of mothers’ dream, design and destiny processes in their relationship with their children in a low socio-economic environment: an appreciative inquiry

This qualitative paper promotes the phenomenological understanding of how mothers from a low socio economic environment (LSEE) envision, design and implement their future perspective of their relationship with their children. In this single instrumental case study ddata were collected through two consecutive focus group discussions with twelve purposefully selected participants, utilising the World Cafe Method and Appreciative Inquiry: 1) to collect data; 2) as a research method that also facilitates change. Findings revealed difficulties envisioning a future and verbalising concepts such as dream, design and destiny. Findings reveal that boundaries are over or under realistic; dreams are clouded by parenting issues, however strong emotional interactions in relationships and wishes to fulfil children’s needs through open respectful communication and friendship exists. Insight is gained that togetherness influences relationships; the present influences the future, especially relating to how discipline is executed. Mothers shared future plans for support. Support needed for possible interventions in building on strengths to promote closeness in their relationships with their children is highlighted.
Location based clustering scheme considering node mobility in wireless sensor networks

In wireless sensor networks, one of key techniques to save power consumption is a clustering. There are several location based clustering schemes. In these methods, a network area is divided into cells, and one node is selected as a cluster head in each cell. Making all nodes except cluster heads sleep, these methods can save power consumption. However, they can be applied to the static network topology. Therefore, we propose a new location based clustering scheme. Our proposed scheme selects a cluster head on the basis of not only residual power but also estimated staying time in a cell. By computer simulations, we show the effectiveness of the proposed scheme with respect to the packet delivery ratio.
Brief survey on image semantic analysis and understanding

Semantic issues are highly concerned with high-level interpretation in image understanding, which include text-image gap and its own affinity. Concentrating on text-formatting with entities in images, three sophisticated methodologies are roundly reviewed as generative, discriminative and descriptive grammar on the basis of contextual features. The following objective benchmark for visual words is also directly presented for semantic coherency. Finally, the summarized directions on semantics in image understanding are discussed intensively for further researches.
The role of arm position during finger flexor strength measurement in sport climbers

The aim of the study was to evaluate the validity and reliability of different arm positions for finger flexor strength measurement in sport climbers. Forty six climbers completed finger flexor strength measurement on a climbing specific device with four different arm positions: 1 - handgrip, shoulder flexed at 0°, elbow fully extended; 2 - shoulder flexed at 90° and externally rotated, elbow flexed at 90° (position 90/90); 3 - shoulder abducted at 130°, elbow flexed at 50° (position 130/50), 4 - shoulder flexed at 180°, elbow fully extended (position 180/0). Intra-session reliability from 3 trials was assessed by an intra-class correlation coefficient (ICC). To assess the criterion related validity repeated analysis of covariance was used (4 x 2 x 2) with the arm position as a within subject factor, sex and climbing ability as between subject factors, and body mass as a covariate. The criterion was represented by self-reported climbing ability. A high ICC was found for all arm positions ranging from 0.95 to 0.98. The highest variability explained by climbing ability in finger strength was found in the 180/0 position (ηp2 = 0.25) and 130/50 position (ηp2 = 0.25). The handgrip test had the lowest validity to the reported climbing ability (ηp2 = 0.05). It was concluded that the positions 180/0 and 130/50 are most suitable to assess finger flexor strength in climbers.
Dendrochronological responses to the 24 October 1992 tornado at Sunset Crater, northern Arizona

This paper documents tree-ring responses to a historic tornado and reevaluates prehistoric tree-ring changes seen in archaeological wood of Wupatki Ruin used to date the 11th-century eruption of Sunset Crater. The historic tor- nado occurred at Sunset Crater, northern Arizona, on 24 October 1992, and trees within areas damaged by the tornado survived the event and continue living today. The objectives of this research were to document their ring-growth changes and to consider the possibility of tornadoes as a candidate disturbance for the prehistoric ring-growth changes of Wupatki. About half of the trees sampled within areas damaged by the tornado show one or more dendrochronological responses to that event, including ring-width release, reaction wood, ring-width suppression, and (or) reduced latewood. Tornado damage is not a likely candidate for having caused the abrupt ring-width changes at AD 1064-1065 seen at Wupatki. However, five living ponderosa pines (Pinus ponderosa Dougl. ex P. & C. Laws.) at Sunset Crater experienced abrupt and severe suppressions in ring growth beginning decades ago and continuing today. No single disturbance seems obvi- ous for causing these growth suppressions, but further research is merited to find the cause of these modern suppres- sions to propose a new candidate explanation for the AD 1064 suppression. Resume : Cet article decrit la reaction des cernes annuels de croissance a une tornade passee et reevalue les changements observes dans les cernes prehistoriques du bois archeologique de Wupatki Ruin qui a ete utilise pour dater les eruptions du Sunset Crater survenus au 11 e siecle. La tornade passee est survenue a Sunset Crater, dans le nord de l'Arizona, le 24 octobre 1992 et des arbres dans la region affectee par la tornade ont survecu et sont toujours vivants aujourd'hui. Les objectifs de cette recherche consistaient a decrire les variations de leur croissance annuelle et a examiner la possi- bilite qu'une tornade soit la perturbation responsable des variations dans les cernes annuels prehistoriques de Wupatki. Environ la moitie des arbres echantillonnes dans la region touchee par la tornade montrent une ou deux reactions den- drochronologiques a cet evenement incluant : des cernes plus larges, du bois de reaction, des cernes plus minces ou moins de bois final. Il y a peu de chances que des dommages dus a une tornade aient cause les changements abrupts
Scheduling of Dynamic In-Game Advertising

Dynamic in-game advertising is a new form of advertising in which ads are served to video game consoles in real time over the Internet. We present a model for the in-game ad-scheduling problem faced by Massive Inc., a wholly owned subsidiary of Microsoft, and a leading global network provider of in-game ad space. Our model has two components: (1) a linear program (solved periodically) establishes target service rates, and (2) a real-time packing heuristic (run whenever a player enters a new level) tracks these service rates. We benchmark our model against Massive’s legacy algorithm: When tested on historical data, we observe (1) an 80%–87% reduction in make-good costs (depending on forecast accuracy), and (2) a shift in the age distribution of served ad space, leaving more premium inventory open for future sales. As a result of our work, Massive has increased the number of unique individuals that see each campaign by, on average, 26% per week and achieved 33% smoother campaign delivery as measured by standard deviation of hourly impressions served.
Monitoring and WCET analysis in COTS multi-core-SoC-based mixed-criticality systems

The performance and power efficiency of multi-core processors are attractive features for safety-critical applications, for example in avionics. But the inherent use of shared resources complicates timing analysability. In this paper we discuss a novel approach to compute the Worst-Case Execution Time (WCET) of multiple hard real-time applications scheduled on a Commercial Off-The-Shelf (COTS) multi-core processor. The analysis is closely coupled with mechanisms for temporal partitioning as, for instance, required in ARINC 653-based systems. Based on a discussion of the challenges for temporal partitioning and timing analysis in multi-core systems, we deduce a generic architecture model. Considering the requirements for re-usability and incremental development and certification, we use this model to describe our integrated analysis approach.