Miracle-dz/UniFAR-FTUs huggingface dataset:
Video Description Generation Incorporating Spatio-Temporal Features and a Soft-Attention Mechanism

Recent progress in using recurrent neural networks (RNNs) for image description has motivated us to explore the application of RNNs to video description. Recent work has also suggested that attention mechanisms may be able to increase performance. To this end, we apply a long short-term memory (LSTM) network in two configurations: with a recently introduced soft-attention mechanism, and without. Our results suggest two things. First, incorporating a soft-attention mechanism into the text generation RNN significantly improves the quality of the descriptions. Second, using a combination of still frame features and dynamic motion-based features can also help. Ultimately, our combined approach exceeds the state-of-art on both BLEU and Meteor on the Youtube2Text dataset. We also present results on a new, larger and more complex dataset of paired video and natural language descriptions based on the use of Descriptive Video Service (DVS) annotations which are now widely available as an additional audio track on many DVDs.
Gain scheduling controller of the aero-engine based on LPV model

Throughout the entire flight envelope for aero engine within its aero-thermodynamic processes will change much, aero-engine control system is designed so that it can in any change of conditions of stable, reliable work, and give full play to your engine's performance benefits. A two-spool turbofan engine nonlinear model to represents a real engine. Depending on linearize nonlinear model to get an engine LPV model, and get the controller gain coefficients of LPV model by linear matrix inequality. Finally, the application of gain scheduling controller with nonlinear model comparing the experimental data proved that the controller reduce the response time and improve steady-state accuracy of engine HP rotor speed.
Loop-Mediated Isothermal Amplification (LAMP) Assay for GMO on: Recent Progresses and Future Perspectives

As more and more genetically modified (GM) crops are approved for commercialization and planting, safety issues of GM crops have become hot topics worldwide. For both regulatory and academic purposes, development of rapid, economic and effective on-site detection methods for GM components is indispensible. Up to now, the most effective and sensitive techniques used for GMO detection are based on polymerase chain reaction (PCR). PCR method needs expensive, heavy instruments and gel electrophoresis, therefore, it is commonly used in laboratory test, and unsuitable for on-site detection. Loop-mediated isothermal amplification (LAMP), an isothermal nucleic acid amplification technique, has been extensively used in many areas such as food safety and clinic diagnosis. Advantageous characteristics of LAMP, such as high specificity and sensitivity, simple operation, low cost, eye visualization, particularly free of special equipment, renders it with high potential to be used for GMO on-site detection. In this review, we summarized current status of the application of LAMP in GMO detection, and discussed possible improvements needed for its adaptability regarding to on-site GMO detection. Hopefully, the information present here would facilitate the practical risk assessment of GMO.
Geometric quality assessment of trajectory‐generated VGI road networks based on the symmetric arc similarity

As large amounts of trajectories from a wide variety of Volunteered Geographic Information (referred to as VGI) contributors pour into the spatial database, the geometric qualities of the VGI road networks generated from these trajectories are different from the ground truth road dataset and so need to be differently assessed. To address this issue, an assessment approach based on symmetric arc similarity is proposed, and the geometric quality of a VGI road network is assessed by its conformity with the corresponding ground truth road network, the results being visualized as hierarchical thematic maps. To compute the conformity, the geometric similarity between the VGI road arc and the corresponding ground truth road arc, which is selected by the adaptive searching distance, is measured based on the symmetric arc similarity method; the geometric quality is assessed based on an assessment matrix. Also, the symmetric arc similarity method is independent of directions and with a feature of shift‐independence, which is applicable to assess the geometric qualities of different VGI road networks and makes the assessment result consistent with the actual situation of the real world. The robustness and scalability of the approach are examined using VGI road networks from different sources.
[A study of the dosage and efficacy of entecavir for treating hepatitis B virus].

OBJECTIVE To evaluate the antiviral activity and safety of entecavir in patients with chronic HBV infection as a preliminarily step in selecting 0.1 mg or 0.5 mg as a better dosage for a further large scale clinical trial. METHODS This was a randomized, double-blinded, placebo-controlled and dose-ranging trial of entecavir usage in 212 patients with chronic HBV infection. The patients were randomly assigned to 3 groups: 0.1 mg entecavir (69), 0.5 mg entecavir (72) and, placebo (71) groups and treated for 28 days. The patients were then followed for 56 days without treatment. RESULTS The proportion of subjects who achieved the primary endpoint at day 28, with their HBV DNA level decreased >2 log or undetectable, was significantly greater in the entecavir 0.1 mg and 0.5 mg dose groups compared with the placebo group (P < 0.01 for both comparisons). The mean change from baseline in HBV DNA levels at day 28 was greater for entecavir 0.1mg and 0.5 mg groups compared with the placebo group (both P < 0.01). The mean change from baseline in HBV DNA levels at day 28 for entecavir 0.5 mg group was greater than that of the entecavir 0.1 mg group (P < 0.01). During the 56-day post-dosing follow-up phase, the entecavir 0.5 mg group was associated with greater and more sustained suppression of viral replication than the entecavir 0.1 mg group (P < 0.01). There were no clinically meaningful differences in the incidence of any adverse events between the entecavir dosing and the placebo groups. CONCLUSION Entecavir at both 0.1 mg and 0.5 mg doses demonstrated superior antiviral activity compared with a placebo. Since the entecavir 0.5 mg dose appears to have greater antiviral activity than the 0.1 mg dose and with a comparable safety and tolerability profile, the 0.5 mg entecavir dose could be used in further trials.
Predominant Mode of Human Immunodeficiency Virus Transfer between T Cells Is Mediated by Sustained Env-Dependent Neutralization-Resistant Virological Synapses

ABSTRACT Cell-free human immunodeficiency virus type 1 (HIV-1) can initiate infections, but contact between infected and uninfected T cells can enhance viral spread through intercellular structures called virological synapses (VS). The relative contribution of VS to cell-free viral transfer has not been carefully measured. Using an ultrasensitive, fluorescent virus transfer assay, we estimate that when VS between HIV-expressing Jurkat T cells and primary CD4+ T cells are formed, cell-associated transfer of virus is 18,000-fold more efficient than uptake of cell-free virus. Furthermore, in contrast to cell-free virus uptake, the VS deposits virus rapidly into focal, trypsin-resistant compartments in target T cells. This massive virus internalization requires Env-CD4 receptor interactions but is resistant to inhibition by patient-derived neutralizing antisera that inhibit homologous cell-free virus. Deleting the Env cytoplasmic tail does not abrogate VS-mediated transfer, but it renders the VS sensitive to neutralizing antibodies, suggesting that the tail limits exposure of VS-neutralizing epitopes on the surface of infected cells. Dynamic live imaging of the VS reveals that HIV-expressing cells are polarized and make sustained, Env-dependent contacts with target cells through uropod-like structures. The polarized T-cell morphology, Env-CD4 coordinated adhesion, and viral transfer from HIV-infected to uninfected cells suggest that VS allows HIV-1 to evade antibody neutralization and to disseminate efficiently. Future studies will discern to what extent this massive viral transfer contributes to productive infection or viral dissemination through the migration of virus-carrying T cells.
Virulence factors in brucellosis: implications for aetiopathogenesis and treatment

Brucella species are responsible for the global zoonotic disease brucellosis. These intracellular pathogens express a set of factors – including lipopolysaccharides, virulence regulator proteins and phosphatidylcholine – to ensure their full virulence. Some virulence factors are essential for invasion of the host cell, whereas others are crucial to avoid elimination by the host. They allow Brucella spp. to survive and proliferate within its replicative vacuole and enable the bacteria to escape detection by the host immune system. Several strategies have been used to develop animal vaccines against brucellosis, but no adequate vaccine yet exists to cure the disease in humans. This is probably due to the complicated pathophysiology of human Brucella spp. infection, which is different than in animal models. Here we review Brucella spp. virulence factors and how they control bacterial trafficking within the host cell.
Draft Genome Sequence of the Broad-Spectrum Xenobiotic Degrader Achromobacter xylosoxidans ADAF13

ABSTRACT Achromobacter xylosoxidans ADAF13, isolated from farmland soil, possesses a large number of putative degradation genes and pathways that break down a wide variety of aromatic hydrocarbons, pesticides, endocrine disruptors, and other high-impact xenobiotics. These properties make this strain an excellent candidate for further development as a broad-spectrum bioremediation agent.
EMI modeling and experiment of a GaN based LLC half-bridge converter

This paper focuses on the electromagnetic interference (EMI) research and analysis of the MHz switching frequency GaN MOSFET based on the LLC resonant DC-DC converter. In this paper, first, the CM coupling paths are studied to get simplified models. Then the impact of the parasitic capacitors (both the capacitors to the ground and the capacitors in the devices) on the CM current are analyzed. Finally the high frequency model is derived from the work above. Moreover this paper makes the comparison between normal Si MOSFET and GaN-based MOSFET behavior in EMI. The modeling result proves that GaN MOSFET has a worse behavior on EMI test. An experiment layout which is aimed at minimizing the irrelevant factors is designed and the experiment result proves the accuracy of the modeling.
[Validation of the INFLESZ scale to evaluate readability of texts aimed at the patient].

BACKGROUND The readability of written texts aimed at patients is an indicator of quality. Szigriszt made an adaptation of the RES Flesch Score, calling it "Escala de Nivel de Perspicuidad" (Clarity Level Scale), to measure the difficulty in reading a text. But Szigriszt used a text sample that was neither representative nor random, which is why the conclusions are not sufficiently consistent. The aim of this article is to complete the process begun by Szigriszt, review the Szigriszt Scale, comparing it with Flesch's scale, and propose a scale according to Spanish reading habits. METHODS Descriptive study. Two hundred and ten documents of 3 types were selected at random: Stationary magazines, school textbooks and scientific magazines. Three fragments of at least 500 words were chosen at random from each one, from the beginning, middle and end. The Flesch-Szigriszt Index (Indice de Legibilidad de Flesch-Szigriszt [IFSZ]), available on the INFLESZ program, was calculated. The scores were classified according to the Flesch and Szigriszt scales. RESULTS The readability of the stationary magazines is 60, of scientific magazines 37.9, and school textbooks 67.39. CONCLUSIONS Only the scientific magazines are situated between 0 and 50. There are no publications with scores lower than 15. Szigrsizt locates "Normal" from 50; Flesch from 60. An intermediate position is adopted and a new scale is proposed: the INFLESZ Scale, which establishes 5 sections: "Very difficult" (<80), "Somewhat difficult" (40-55), "Normal" (55-65), "Quite easy" (65-80) and "Very easy" (>80). Neither the Clarity Level Scale of Szigriszt nor the RES Flesch Score are adapted to Spanish reading habits. In the case of texts on health, there is a greater probability of their being read and understood if they exceed 55.
The extracellular matrix is a novel attribute of endothelial progenitors and of hypoxic mature endothelial cells

Extracellular matrix (ECM) production is critical to preserve the function and integrity of mature blood vessels. Toward the engineering of blood vessels, studies have centered on ECM production by supporting cells, whereas few studies implicate endothelial cells (ECs) with ECM synthesis. Here, we elucidate variations between cultured human arterial, venous, and progenitor ECs with respect to ECM deposition assembly, composition, and response to biomolecular and physiological factors. Our studies reveal that progenitor ECs, endothelial colony‐forming cells (ECFCs), deposit collagen IV, fibronectin, and laminin that assemble to an organized weblike structure, as confirmed by decellularized cultures. Mature ECs only express these ECM proteins intracellularly. ECFC‐derived ECM is abrogated in response to TGFβ signaling inhibition and actin cytoskeleton disruption. Hypoxic (1%) and physiological (5%) O2 tension stimulate ECM deposition from mature ECs. Interestingly, deposition of collagen I is observed only under 5% O2 tension. ECM production from all ECs is found to be regulated by hypoxia‐inducible factors 1α and 2α but differentially in the different cell lines. Collectively, we suggest that ECM deposition and assembly by ECs is dependent on maturation stage and oxygen supply and that these findings can be harnessed to advance engineered vascular therapeutics. —Kusuma, S. , Zhao, S. , Gerecht, S. The extracellular matrix is a novel attribute of endothelial progenitors and of hypoxic mature endothelial cells. FASEB J. 26, 4925–4936 (2012). www.fasebj. org
Does Measuring Body Weight Impact Subsequent Response to Eating Behavior Questions?

Objectives: If being weighed impacts perceptions of eating behavior, it is important that the order of questionnaires and weighing be considered in research and practice. A quasi-experimental study was performed to examine whether being weighed immediately prior to completing a questionnaire affects responses to eating behavior questions. It was hypothesized that being weighed would serve as a priming stimulus and increase measures of dietary restraint, disinhibition, and hunger. Methods: Trained researchers collected a sample of volunteers (n = 355) in 8 locations in the United States on two Saturdays in the summer of 2011. Half of the participants were weighed immediately prior to completing the Three Factor Eating Questionnaire (TFEQ), with the remaining half weighed immediately after TFEQ completion. Results: A priori hypotheses were not supported despite replicating known relationships between weight, dietary restraint and disinhibition. Results indicated that being weighed first produced a difference in differences on disinhibition scores between low restraint score (95% CI = 4.65–6.02) and high restraint score (95% CI = 6.11–7.57) compared to being weighed after questionnaire completion (p = 0.003). However, this relationship was not significant when modeling restraint as a continuous variable, questioning the use of dichotomization. Conclusions: Being weighed is unlikely to be a strong enough prime to significantly change scores on eating behavior questionnaires for everyone, but may allow differences in restraint status to become more evident. Researchers assessing dietary restraint should be wary of the possibility of producing different results when treating restraint as continuous or dichotomous, which could lead to different interpretations.
The Holistic Worldview in Action

The American Holistic Nurses Credentialing Corporation (AHNCC), the only national credentialing body for holistic nurses, has a responsibility to offer valid, reliable, and rigorous certification examinations and to grow and evolve as indicated by social and professional changes. This article describes four major changes in the work of AHNCC since 2004: a detection of an evolution in the domain of holistic nursing through review of the literature; clarification and specification of levels of practice by educational level; development of the nurse coach role in nursing, designed within the precepts of holistic nursing; and AHNCC’s response to the social paradigm shift for health care, and nursing’s advanced practice registered nurse consensus model. Each of these is discussed in detail describing the circumstances that perpetuated AHNCC’s consideration and the actions taken by AHNCC.
Underwater Sonar Signals Recognition by Incremental Data Stream Mining with Conflict Analysis

Sonar signals recognition is an important task in detecting the presence of some significant objects under the sea. In military, sonar signals are used in lieu of visuals to navigate underwater and/or locate enemy submarines in proximity. In particular, classification algorithm in data mining has been applied in sonar signal recognition for recognizing the type of surfaces from which the sonar waves are bounced. Classification algorithms in traditional data mining approach offer fair accuracy by training a classification model with the full dataset, in batches. It is well known that sonar signals are continuous and they are collected as data streams. Although the earlier classification algorithms are effective in traditional batch training, it may not be practical for incremental classifier learning. Since sonar signal data streams can amount to infinity, the data preprocessing time must be kept to a minimum to fulfill the need for high speed. This paper presents an alternative data mining strategy suitable for the progressive purging of noisy data via fast conflict analysis from the data stream without the need to learn from the whole dataset at one time. Simulation experiments are conducted and superior results are observed in supporting the efficacy of the methodology.
Mutual authentication protocol using identity-based shared secret key in cloud environments

In this era of technology, cloud computing is a rapidly developing technology. Which will widely use as Everything-as-a-service to provide various services like SaaS, PaaS, DaaS, and IaaS etc. In infrastructure as a service when two or more system communicate between them, then their need of mutual authentication is required for secure and safe communication in same infrastructure. In this we are used Identity-based techniques for mutual authentication in same network or infrastructure called private clouds. We proposed an algorithm for mutual authentication in which we generate a shared key or group key for mutual Authentication and secure communication. In algorithm is much secure and safe then other general mutual authentication algorithm.
Six-qubit permutation-based decoherence-free orthogonal basis

There is a natural orthogonal basis of the 6-qubit decoherence-free (DF) space robust against collective noise. Interestingly, most of the basis states can be obtained from one another just permuting qubits. This property (a) is useful for encoding qubits in DF subspaces, (b) allows the implementation of the Bennett-Brassard 1984 (BB84) protocol in DF subspaces just permuting qubits, which completes the method for quantum key distribution using DF states proposed by Boileau et al. [Phys. Rev. Lett. 92, 017901 (2004)], and (c) points out that there is only one 6-qubit DF state which is essentially new (not obtained by permutations) and therefore constitutes an interesting experimental challenge.
Improved phase-locked loop under heavily distorted grid condition

This paper proposes a novel phase-locked loop (PLL) for grid synchronization based on the moving average filter (MAF) and the weighted least squares estimation (WLSE) scheme, namely WLSE-PLL. The MAF can eliminate all the odd-order harmonics and the fundamental negative-sequence component. The WLSE is employed to estimate the fundamental positive-sequence component (FPS). Combining the zero crossing detection (ZCD) and the frequency locked-loop (FLL), the WLSE-PLL is also adaptive to frequency deviation. Through analysis and simulation, the WLSE-PLL is proved to have a fast response and a satisfactory performance even under heavily distorted grid conditions including three-phase unbalance, dc offset and harmonics.
The Implicit Structure of Positive Characteristics

The implicit structure of positive character traits was examined in two studies of 190 and 100 undergraduates. Participants judged the pairwise covariation or semantic similarity of 42 positive characteristics using a sorting or a rating task. Characteristics were drawn from a new classification of strengths and virtues, the Five-Factor Model, and a taxonomy of values. Participants showed consistent patterns of perceived association among the characteristics across the study conditions. Multidimensional scaling yielded three consistent dimensions underlying these judgments (“warmth vs. self-control,” “vivacity vs. decency,” and “wisdom vs. power”). Cluster analyses yielded six consistent groupings—“self-control,” “love,” “wisdom,” “drive,” “vivacity,” and “collaboration”—that corresponded only moderately to the virtue classification. All three taxonomies were systematically related to this implicit structure, but none captured it satisfactorily on its own. Revisions to positive psychology’s classification of strengths are proposed.
A Purified Agonist-Activated G-Protein Coupled Receptor: Truncated Octopus Acid Metarhodopsin

Abstract G-protein coupled receptors (GPCRs) mediate responses to many types of extracellular signals. So far, bovine rhodopsin, the inactive form of a GPCR, is the only member of the family whose three dimensional structure has been determined. It would be desirable to determine the structure of the active form of a GPCR. In this paper, we report the large scale preparation of a stable, homogenous species, truncated octopus rhodopsin (t-rhodopsin) in which proteolysis has removed the proline-rich C-terminal; this species retains the spectral properties and the ability for light-induced G-protein activation of unproteolyzed octopus rhodopsin. Moreover, starting from this species we can prepare a pure, active form of pigment, octopus t-Acid Metarhodopsin which has an all-trans-retinal as its agonist. Photoisomerization of t-Acid Metarhodopsin leads back to the inactive form, t-rhodopsin with the inverse agonist 11-cis-retinal. Octopus t-Acid Metarhodopsin can activate an endogenous octopus G-protein in the dark and this activity is reduced by irradiation with orange light which photoregenerates t-Acid Metarhodopsin back to the initial species, t-rhodopsin.