Miracle-dz/UniFAR-FTUs huggingface dataset:
Validity of self-reported physical work load in epidemiologic studies on musculoskeletal disorders.

OBJECTIVES This study assessed the validity of self-reported physical work load by questionnaire and logbook against task analysis and observation. It also investigated factors (job type and low-back or neck pain) affecting the self-assessment of physical work load and compared the assessments between the questionnaire and the logbook. METHODS A self-administered questionnaire including 10 questions (ordinal scales) on physical work load and musculoskeletal symptoms was filled out by 2756 men in the forest industry. From this population, 36 men were selected for task analysis and observation. Logbooks including 10 continuous variables were analyzed for 386 men. RESULTS The Spearman rank correlation coefficients between the self-assessments and observations for the frequency of manual handling, duration of trunk flexion, neck rotation, hand above shoulder level, and squatting or kneeling ranged between 0.42 and 0.55. The correlation coefficients for the questionnaire items were higher in general, and the accuracy better, for those with no low-back pain than for those with pain. The duration of trunk flexion, neck flexion and hand above shoulder level was overestimated in the questionnaires and less so in the logbooks. CONCLUSIONS Self-administered questionnaires may help to classify groups with heterogeneous occupational tasks according to some work-load factors. The accuracy of the assessments is not good for studying quantitative exposure-effect relationships, however. The logbook method might give more valid information. The perception of musculoskeletal pain may bias the self-assessment of work load.
Persistence-based Interest Point Detection for 3D Deformable Surface

Several approaches for interest point detection on rigid shapes have been proposed, but few are available for non-rigid shapes. It is a very challenging task due to the presence of the large degrees of local deformations. This paper presents a novel method called persistence-based heat kernel signature (pHKS). It consists of two steps: Scalar field construction and interest point detection. We propose to use the heat kernel signature function at a moderately small time scale to construct the scalar field. It has the advantage of being stable under various transformations. Based on the predefined scalar field, a 0-dimensional persistence diagram is computed, and the local geometric and global structural information of the shape are captured at the same time. Points with local maxima and high persistence are selected as interest points. We perform a comprehensive evaluation on two popular datasets (i.e., PHOTOMESH and Interest Points Dataset) to show the effectiveness of our method. Compared with existing techniques, our interest point detector achieves a superior performance in terms of repeatability and distinctiveness.
Isoenzymes of Superoxide Dismutase in Nodules of Phaseolus vulgaris L., Pisum sativum L., and Vigna unguiculata (L.) Walp.

The activity and isozymic composition of superoxide dismutase (SOD; EC 1.15.1.1) were determined in nodules of Phaseolus vulgaris L. , Pisum sativum L. , and Vigna unguiculata (L.) Walp. formed by Rhizobium phaseoll 3622, R. Ieguminosarum 3855, and Bradyrhizobium sp. BR7301, respectively. A Mn-SOD was present in Rhizobium and two in Bradyrhizobium and bacteroids. Nodule mitochondria from all three legume species had a single Mn-SOD with similar relative mobility, whereas the cytosol contained several CuZn-SODs: two in Phaseolus and Pisum, and four in Vigna. In the cytoplasm of V. unguiculata nodules, a Fe-containing SOD was also present, with an electrophoretic mobility between those of CuZn- and Mn-SODs, and an estimated molecular weight of 57,000. Total SOD activity of the soluble fraction of host cells, expressed on a nodule fresh weight basis, exceeded markedly that of bacteroids. Likewise, specific SOD activities of free-living bacteria were superior or equal to those of their symbiotic forms. Soluble extracts of bacteria and bacteroids did not show peroxidase activity (EC 1.11.1.7), but the nodule cell cytoplasm contained diverse peroxidase isozymes which were readily distinguishable from leghemoglobin components by electrophoresis. Data indicated that peroxidases and leghemoglobins did not significantly interfere with SOD localization on gels. Treatment with chloroform-ethanol scarcely affected the isozymic pattern of SODs and peroxidases, and had limited success in the removal of leghemoglobin.
A compact STED microscope providing 3D nanoscale resolution

The advent of supercontinuum laser sources has enabled the implementation of compact and tunable stimulated emission depletion fluorescence microscopes for imaging far below the diffraction barrier. Here we report on an enhanced version of this approach displaying an all‐physics based resolution down to (19 ± 3) nm in the focal plane. Alternatively, this single objective lens system can be configured for 3D imaging with resolution down to 45 × 45 × 108 nm in a cell. The obtained results can be further improved by mathematical restoration algorithms. The far‐field optical nanoscale resolution is attained in a variety of biological samples featuring strong variations in the local density of features.
On-Scene Determination of Driver Crash Causation and Avoidance Maneuvers in Rear-end Collisions

Rear-end collisions are one of the most frequent crash types in the United States (U.S.) Pre-Collision System (PCS) have been developed to mitigate the frequency and severity of rear-end collisions. The potential effectiveness of these systems, however, depends on the driver’s state and their attempted avoidance maneuvers. This study utilized the National Motor Vehicle Crash Causation Survey (NMVCCS), a unique nationally representative dataset focused on crash causation, to quantify contributing factors in rear-end collisions and the avoidance maneuvers attempted by drivers of the striking vehicle. For a case to be included in NMVCSS, the crash site had to be visited by an investigator prior to the scene being cleared. Rear-end collisions were more likely to involve a driver that was following too closely, inattentive, distracted by a non-driving activity, focusing on external factors, exhibiting inadequate surveillance, and making false assumptions of other drivers’ actions compared to other frontal collisions. Compared to other frontal collisions, rear-end collisions were more likely to have occurred on roadways with traffic flow restrictions, speed limits at highway speeds, multiple lanes, and relation to a junction (e.g. intersections, on-ramps, merging zones). In 72% of rear-end collision the driver attempted an avoidance maneuver. Of those drivers attempting an avoidance maneuver, 67% only applied the brakes, 27% applied the brakes with steering, and 6% only steered. Conversing and non-driving activities were found to be significant factors indicating the lack of an avoidance maneuver in rear-end collisions. In all rear-end collisions, Forward Collision Warning and Pre-Crash Brake Assist could be potentially effective in 84% of crashes, while Autonomous Braking could be effective in 90% of crashes.
Declining Estrogen Receptor-&bgr; Expression Defines Malignant Progression of Human Breast Neoplasia

It has been shown that the risk of breast cancer developing in certain morphologically identifiable benign breast lesions correlates with expression of estrogen receptor alpha (ER-&agr;). Although ER-&agr; and ER-&bgr; genes share a large degree of homology, it is generally thought that their distribution and functions are substantially different in many tissues. Recent development of reliable antibodies to ER-&bgr; has provided this first opportunity to test the hypothesis that the likelihood of malignant transformation in morphologically benign breast lesions can be accurately defined by the distribution and level of ER-&bgr; expression relative to that of ER-&agr;. Using a monoclonal antibody, ER-&bgr; protein expression has been analyzed in 53 normal breasts and compared with a cohort of histologically distinct breast lesions of different prognostic risk (54 hyperplasia of usual type, 35 ductal carcinoma in situ, and 141 invasive cancers). All of these tissues were also assessed for ER-&agr;. Expression of ER-&bgr; protein was also analyzed in an additional spectrum of benign breast lesions with low or negligible risk of progression to malignancy. The median proportion of cells expressing ER-&bgr; was highest in normal breast lobules (median 94.33%, interquartile range 78.25–99.00) but declined significantly through usual ductal hyperplasia (median 76.67, interquartile range 49.17–95.00, P = 0.002) and ductal carcinoma in situ (median 70.00, interquartile range 59.00–85.00, P = 0.009) to invasive cancer (median 60.00, interquartile range 50.00–80.00, P < 0.001). An appreciable proportion (33.81%) of ER-&agr;-negative invasive cancers expressed ER-&bgr;. A high but variable level of ER-&bgr; expression occurred in the benign lesions. The data from the intact histologic tissues were evaluated with respect to the relative expression of ER-&agr; and ER-&bgr; in five mammary cell lines of different behavioral phenotype (MCF7, ZR-75, T47D, MDAMB231, HUMA121). The highly significant differences in expression and distinct tissue distributions of ER-&agr; and ER-&bgr; within the histologic lesions of defined risk, together with the data from the cell lines, support the original hypothesis that the tissue concentration, relative occurrence, and/or interaction of these two types of estrogen receptor may play an important role in modulating mammary tumorigenesis.
Interactions among elk, aspen, galling sawflies and insectivorous birds

Using two years of observational and experimental data, we examined the hypothesis that browsing by elk on aspen indirectly affects the distribution of a leaf-galling sawfly, which in turn affects insect diversity and foraging patterns of insectivorous birds. We found that: i) in an analyses of 33 arthropod species, the presence of sawflies significantly increased arthropod richness and abundance by 2 X and 2.5 X, respectively. ii) browsing by elk reduced sawfly gall abundance such that 90% of the galls were found on unbrowsed aspen ramets. iii) insectivorous birds attacked 60‐74% of the galls on unbrowsed shoots compared to 11% on browsed shoots. When leaf-galler abundance was experimentally held constant on browsed and unbrowsed shoots, predation by insectivorous birds did not differ significantly. This result suggests that browsing affects the patterns of avian predation by altering the distribution of a galling insect. These data argue that bottom-up, top-down, and lateral factors can act in concert to affect the distribution of a galler, structure arthropod communities and affect predation by insectivorous birds.
Semantic Similarity based Clustering of License Excerpts for Improved End-User Interpretation

With the omnipresent availability and use of cloud services, software tools, Web portals or services, legal contracts in the form of End-User License Agreements (EULA) regulating their use are of paramount importance. Often the textual documents describing these regulations comprise many pages and can not be reasonably assumed to be read and understood by humans. In this work, we describe a method for extracting and clustering relevant parts of such documents, including permissions, obligations, and prohibitions. The clustering is based on semantic similarity employing a distributional semantics approach on large word embeddings database. An evaluation shows that it can significantly improve human comprehension and that improved feature-based clustering has a potential to further reduce the time required for EULA digestion. Our implementation is available as a web service, which can directly be used to process and prepare legal usage contracts.
Sleep duration and health-related quality of life among older adults: a population-based cohort in Spain.

STUDY OBJECTIVES The few studies that have addressed the association between sleep duration and health-related quality of life (HRQL) were cross-sectional and small-sized, targeted young and middle-aged persons, and did not adjust for the main confounders. This study sought to examine the cross-sectional and longitudinal relationship between habitual sleep duration and HRQL in older adults. DESIGN Prospective study conducted from 2001 through 2003. Sleep duration was self-reported in 2001, and HRQL was measured using the SF-36 questionnaire in 2001 and 2003. Analyses were adjusted for the main confounders. SETTING Community-based study. PARTICIPANTS A cohort of 3834 persons representative of the non-institutionalized Spanish population aged 60 years and over. INTERVENTION None. MEASUREMENT AND RESULTS In comparison with women who slept 7 hours, those with extreme sleep durations (< or = 5 or > or = 10 h) reported worse scores on the SF-36 physical and mental scales in 2001. Among men, sleeping < or = 5 h was associated with a worse score in the role-physical scale in 2001. The magnitude of most of these associations was comparable with the reduction in HRQL associated with aging 10 years. Sleep duration in 2001 failed to predict changes in HRQL between 2001 and 2003. CONCLUSION Extreme sleep durations are a marker of worse HRQL in the elderly.
A method for the synthesis of liveness enforcing supervisors in Petri nets

Given an arbitrary Petri net structure, which may have uncontrollable and unobservable transitions and may be unbounded, the procedure described in this paper generates a supervisor for liveness enforcement. The supervisor is specified as a conjunction of linear marking inequalities. For all initial markings satisfying the linear marking inequalities, the supervised Petri net is live. Moreover, the supervision is least restrictive in the fully controllable and observable case.
NUTRITIONAL AND ORGANOLEPTIC EVALUATION OF COOKIES FROM PIGEON PEA ( Cajanus cajan ) AND COCOYAM ( Xanthosoma sp ) FLOUR BLENDS

Cookies were made from pigeon pea (Cajanus cajan) and cocoyam (Xanthosoma sagittifolium) flour blends. Pigeon pea flour (PPF) was mixed with cocoyam flour (CF) at ratios of 20:80, 30:70, 40:60, 50:50 and 60:40 respectively. The cookies were evaluated for proximate composition, saponins, oxalate, trypsin inhibitors, in-vitro protein digestibility, in-vitro carbohydrate digestibility, physical and sensory qualities. Standard experimental protocols were employed in the estimation of all indices. The protein contents of the cookies were significantly different (p<0.05) from each other and ranged from 10.89 to 11.60% with cookies from 60:40 PPF to CF having the highest value of 11.60% and cookies 20:80 PPF to CF having the least value of 10.89%. The levels of antinutrients analyzed were low with saponin content ranging from 0.05 to 0.08mg/100g; trypsin inhibitors ranging from 0.08 to 0.11mg/100g and oxalate content between 0.06 to 0.68mg/100g. There were significant differences (p<0.05) observed in the in-vitro digestibility (protein and carbohydrate) with cookies made from 20:80 PPF to CF having the highest protein and carbohydrate in-vitro digestibilities of 64.81% and 67.35%, respectively. Results from the physical evaluation of the cookies revealed that the diameter and spread ratio of the cookies were significantly different (p<0.05) from each other and decreased with increasing levels of pigeon pea flour. Data obtained from the sensory evaluation indicated that the mean scores for taste, colour, general acceptability and texture were generally high for cookies containing at least 50% cocoyam flour. However, cookies made from 20:80 PPF to CF had the highest mean scores for all the parameters assessed and were not significantly (p>0.05)different from the control (100% wheat). It may, therefore be concluded from the strength of this work that cookies produced from 20% pigeon pea flour and 80% cocoyam flour have great potential as they compared favourably with cookies produced from wheat. The use of this composite flour would go a long way in reducing dependency on wheat flour in countries that import wheat.
Cost-effectiveness of a specialized atrial fibrillation clinic vs. usual care in patients with atrial fibrillation.

AIMS A recent randomized controlled trial demonstrated significant reductions in cardiovascular hospitalizations and deaths with a nurse-led integrated chronic care approach in patients with atrial fibrillation (AF) compared with usual care. The aim of the present study is to assess cost-effectiveness of this nurse-led care programme vs. usual care. METHODS AND RESULTS A cost-effectiveness analysis was undertaken alongside the randomized controlled trial in which 712 patients were included at the Maastricht University Medical Centre, The Netherlands, and allocated to nurse-led care or usual care. Nurse-led care implied guideline-adherent management, steered by dedicated software, supervised by cardiologists. Usual care was regular outpatient care performed by cardiologists. A cost per life-year and a cost per quality-adjusted life-year (QALY) analysis was performed, both from a hospital perspective. The nurse-led care programme was associated with slightly more life-years and QALYs at a lower cost. Specifically, the nurse-led programme contributed to 0.009 QALY gains with a reduced cost of €1109 per patient and a gain of 0.02 life-years with a reduced cost of €735 per patient. Therefore, the nurse-led programme would be considered dominant. In fact, for all the possible values of willingness to pay for a QALY the nurse-led programme is considered to be more likely cost-effective than the care as usual. CONCLUSION The cost-effectiveness analysis in the present study demonstrated that a nurse-led integrated care approach will save costs and improve survival and quality of life, and is therefore a cost-effective management strategy for patients with AF.
BLOOD PRESSURE IN DANISH CHILDREN and ADOLESCENTS

Abstract. Ibsen, K. Kaas (University Paediatric Clinic, Children's Hospital, Fugle‐bakken, Copenhagen, Denmark). Blood pressure in Danish children and adolescents. Acta Paediatr Scand, 70:27, 1981. –Blood pressure was measured in 946 Danish schoolchildren aged 7 to 18 years. The children had been randomly selected and serve as an urban reference population. Blood pressure was measured in 52 different schools, with the same Random‐Zero‐Sphygmomanometer, and all pressures were measured by the same person, under standardized conditions, to eliminate as many sources of error and uncertainties as possible. For both sexes an age‐dependent significant increase in both systolic and diastolic blood pressure was observed. For both the systolic and the diastolic pressures, significant differences in blood presure measured before and after blood testing were observed.
Supporting Climate Impact Research by a Smart View Management

Climate impact research investigates the consequences of climate change to varying systems, like ecological systems. For this purpose a lot of different models and parameter settings simulating the future development of these systems are specified and explored. Typically, desktop systems are applied which limit the number of simultaneously displayable views. On the other hand, multi-display environments allow the presentation of multiple views at the same time. In particular, Smart Meeting Rooms support different users bringing in their own personal devices and systems working in such multi-display environment. This paper discusses the use of the Vegetation Visualizer, a system supporting the visual presentation of varying attributes of climate impact models, within a Smart Meeting Room. On this example we show that the Smart View Management can be easily used as a software base to integrate different applications into a Smart Meeting Room.
CRINet: A secure and fault-tolerant data collection scheme using 3-way forwarding and group key management in wireless sensor networks

A critical security threat in a WSN is the compromising of sensor nodes. Not only can attackers use such vulnerability to eavesdrop on the dataflow, but could also inject bogus information into the network. However, most current secure data collection methods trade fault-tolerant ability for end-to-end protection, thus with poor performance. This work proposes CRINet, a secure and fault-tolerant data collection scheme with group key management mechanism. To achieve high reliability, sensing data would be transferred to the sink through multi-path. EBS is applied in CRINet for group key management in order to reduce re-key efforts. Simulation results demonstrate that CRINet scheme is superior in terms of data confidentiality and availability.
Binary Matrix Factorization and Consensus Algorithms

In data mining, SVD is a popular method that has been used for compressing high dimensional data. Binary matrix factorization (BMF) is a variant of SVD. There are two methods for binary factorization compression: the iterative heuristic and greedy algorithms. However, both of them are not perfect in applications. The iterative heuristic does not guarantee the convergence in most cases and greedy algorithms can't fit the need of large-scale matrices factorization. In this paper a new method is used for BMF: consensus algorithms. Consensus algorithms are a brand-new approach to enumerating all the maximal bicliques for a given graph, which is proved to be an NP-complete problem and can give the solution in incremental polynomial time. For some bipartite graphs, the time complexity is polynomial. Experiments show that when the iterative heuristic does not work, consensus algorithm improves far more badly the efficiency than greedy algorithms, and ensures the stability.
Mining of Association Rules in Distributed Databases

: Data mining is the most fast growing area today which is used to extract important knowledge from large data collections but often these collections are divided among several parties . Association rule mining is one of the techniques in data mining. Here , we propose a protocol for mining of association rules in horizontally distributed databases and protocol is based on the Fast Distributed Mining (FDM) algorithm which is an unsecured distributed version of the Apriori algorithm. The main ingredients in protocol are two novel secure multi-party algorithms — one that computes the union of private subsets that each of the interacting players hold, and another that tests the inclusion of an element held by one player in a subset held by another. Our protocol offers enhanced privacy with respect to the protocol. In addition, it is simpler and is signiﬁcantly more efficient in terms of communication rounds, communication cost and computational cost.
N-(2,5-Dimethylphenyl)succinamic acid monohydrate

In the title compound, C12H15NO3·H2O, the conformation of the N—H bond in the amide segment is syn to the ortho-methyl group and anti to the meta-methyl group in the benzene ring. Further, the conformations of the amide O and the carbonyl O atom of the acid segment are anti to the adjacent methylene H atoms. The C=O and O—H bonds of the acid group are syn to one another. The structure shows an interesting hydrogen-bonding pattern with the water molecule forming hydrogen bonds with three different molecules of the compound. In the crystal, molecules are packed into infinite chains through intermolecular O—H⋯O and N—H⋯O hydrogen bonds.