Miracle-dz/UniFAR-FTUs huggingface dataset:
An optimized velocity selective arterial spin labeling module with reduced eddy current sensitivity for improved perfusion quantification

Velocity‐selective (VS) arterial spin labeling is a promising method for measuring perfusion in areas of slow or collateral flow by eliminating the bolus arrival delay associated with other spin labeling techniques. However, B0 and B1 inhomogeneities and eddy currents during the VS preparation hinder accurate quantification of perfusion with VS arterial spin labeling. In this study, it is demonstrated through simulations and experiments in healthy volunteers that eddy currents cause erroneous tagging of static tissue. Consequently, mean gray matter perfusion is overestimated by up to a factor of 2, depending on the VS preparation used. A novel eight‐segment B1 insensitive rotation VS preparation is proposed to reduce eddy current effects while maintaining the B0 and B1 insensitivity of previous preparations. Compared to two previous VS preparations, the eight‐segment B1 insensitive rotation is the most robust to eddy currents and should improve the quality and reliability of VS arterial spin labeling measurements in future studies. Magn Reson Med, 2013. © 2012 Wiley Periodicals, Inc.
Generating Rational Models (Poster Abstract)

My talk is on original research using past voting results of individual states for the past eleven Presidential elections to get a states power by using regression and the Shapley-Shubik Power Index. Presidential campaign resource allocation is determined after the states power has been calculated. The poster will discuss how to construct the Buckyball from PHIZZ units and show how the Buckyball can be properly three-colored using Hamiltonian circuits. Also, it will discuss how using Euler's formula you can prove that all Buckyballs contain 12 pentagons and how this relates to the number of pieces needed to construct the spheres with PHIZZ units. The poster is meant to cover the topic of God's algorithm on the edges and corners of the Rubik's Cube. Using proofs for the size of the Rubik's Cube group, along with computer programs that make use of these proofs, the poster will show/ describe/ explain God's Algorithm for the edges alone (and the corners alone) of the Rubik's Cube. The poster will demonstrate the use of generating functions to determine mathematical identities within the Fibonacci Sequence. This talk will introduce elliptic curves and magic squares and the connection between them. It will answer the question: Do points of order dividing n on elliptic curves form a magic square? Algorithms for forming these magic squares will be introduced and discussed. On a violin string, harmonics only occur at rational points; however, the probability of hitting a rational point on [0,1] is 0. In light of this, one wonders how a harmonic can be generated so easily on a real violin. We discuss this point in the context of the wave equation. (**) Biquadratic Indentity of the Cevian line subalgebra We define the Cevian Algebra on the interior points of a triangle. We will present some properties of Cevian Algebra including the Biquadratic identity. When Fibonacci numbers are represented in binary form many interesting patterns arise. In this talk we will discuss and explain some of these patterns. We hypothesize that self-avoiding walk problems serve as a sufficient model for polymers. In this study, using square lattices to depict certain subclasses of self-avoiding walks we claim to get adequate
SEPARATION OF SCALES IN AN ELASTIC INVERSE PROBLEM

Elastography is an imaging modality of Young's Modulus of a biological medium (breast, liver,.). It consists of vibrating a medium and infer from the observed wavefield the distribution of elasticity. The displacement field is observed in the all volume. It thus requires to solve an inverse problem. We present an optimization approach which solves the problem by minimizing a discrepancy functional. When we want to recover a complex inclusion in homogenous medium, we notice that the information contained in the wavefield should be decomposed into two parts, a near field close from the inclusion and a far field part away from it. As we justify theoretically and numerically, separating these scales allows us have a local and precise reconstruction. Resume. L'elastographie est une technique d'imagerie de l'´elasticite des tissus du corps humain (sein, foie,. .). Cela consistefaire vibrer un milieu etobserver dans le volume le champ de deplacement induit, afin d'en deduire la carte de module d'Young. Il faut pour cela resoudre un probleme inverse. Nous proposons une approche par optimisation qui maximise la vraisemblance entre un modele numerique et les observations experimentales. En voulant reconstruire une inclusion complexe, nous remarquons que l'information contenue dans le champ de deplacement se separe en deux termes, de champs proche au voisinage de l'inclusion, et de champ lointaingrande distance du defaut. Nous justifions theoriquement et numeriquement qu'il est profitable de separer ces deux informations pour obtenir une reconstruction locale et precise.
Glass Transition

Computer simulations of melting, crystallization, glass transition, and annealing for a model system of 864 Lennard-Jones (LJ) atoms under a periodic boundary condition are carried out using constant-pressure molec ular dynamics techniques with temperature control. When an fcc crystal of LJ atoms is heated, melting occurs; however, an LJ liquid, when quenched slowly, crystallizes into layers with stacking faults. Each layer forms a two-dimensional, close-packed structure with occasional point defects but without dislocations. When the quench rate is high enough, an LJ liquid transforms into a disordered structure without a discontinuous change in volume. The dependence of the glass transi tion on the quench rate is determined by examining macroscopically observable physical features. Several microscopic structure parameters are introduced to ana lyze, at the atomic level, the structures of glasses pro duced by different quench rates. When annealed, a glass made with a low enough quench rate is stable against crystallization. Identifying the number of atoms in the system having local icosahedral symmetry is a prom ising method of characterizing the glass's stability. The microscopic structural changes in the annealing pro cesses are presented in the companion video to this paper.
Can the patient on medication be sent to 12-step programs?

Alcoholism and other drug dependence treatment professionals have long been concerned about the patient on psychotropic medication who may be told by Alcoholics Anonymous (AA) members that this is incompatible with the 12-Step program . Historically, alcoholics and other drug abusers have used illegal and prescription drugs, both in conjunction with alcohol and as a substitute for alcohol, thus sidetracking their recovery. Many were able to manipulate physicians into supplying prescriptions for an ever-growing drug habit. In addition, physicians vary greatly in their sophistication about substance abuse problems and some may unwittingly offer medication that is unnecessary or even contraindicated. These and other factors have led 12-Step program members to be wary about the use of medication, and in some groups the message is conveyed that medication precludes sincere and effective participation . Unfortunately. there are many people with substance abuse problems who also have disorders that are appropriately treated with prescribed medication . These disorders include psychotic problems . major affective disorders and some anxiety disorders. Patients with these conditions are unlikely to maintain abstinence unless they are concurrent! y treated for their other problems. They arc often urged by treatment providers to deve lop meaningful 12-Step participation for the many additional resources this provides . Many such individuals beg in to establish ties with particular 12-Step groups and then find them-
Correlation of Fluconazole MICs with Clinical Outcome in Cryptococcal Infection

ABSTRACT We have correlated the in vitro results of testing the susceptibility of Cryptococcus neoformans to fluconazole with the clinical outcome after fluconazole maintenance therapy in patients with AIDS-associated cryptococcal disease. A total of 28 isolates of C. neoformans from 25 patients (24 AIDS patients) were tested. The MICs were determined by the broth microdilution technique by following the modified guidelines described in National Committee for Clinical Standards (NCCLS) document M27-A, e.g., use of yeast nitrogen base medium and a final inoculum of 104 CFU/ml. The fluconazole MIC at which 50% of isolates are inhibited (MIC50) and MIC90, obtained spectrophotometrically after 48 h of incubation, were 4 and 16 μg/ml, respectively. Of the 25 patients studied, 4 died of active cryptococcal disease and 2 died of other causes. Therapeutic failure was observed in five patients who were infected with isolates for which fluconazole MICs were ≥16 μg/ml. Four of these patients had previously had oropharyngeal candidiasis (OPC); three had previously had episodes of cryptococcal infection, and all five treatment failure patients had high cryptococcal antigen titers in either serum or cerebrospinal fluid (titers, >1:4,000). Although 14 of the 18 patients who responded to fluconazole therapy had previously had OPC infections, they each had only a single episode of cryptococcal infection. It appears that the clinical outcome after fluconazole maintenance therapy may be better when the infecting C. neoformans strain is inhibited by lower concentrations of fluconazole for eradication (MICs, <16 μg/ml) than when the patients are infected with strains that require higher fluconazole concentrations (MICs, ≥16 μg/ml). These findings also suggest that the MICs determined by the modified NCCLS microdilution method can be potential predictors of the clinical response to fluconazole therapy and may aid in the identification of patients who will not respond to fluconazole therapy.
The adoption of personalized music services - Combining qualitative and quantitative research -

In the last decade the music industry has been developing different Internet based music services. Lately personalization via recommendation is gaining popularity. In this paper we investigate the adoption of personalized music services by a combined quantitative and qualitative research approach. We first deploy an adoption study by the use of an adapted TAM survey. Our quantitative findings confirm perceived enjoyment as influential factor for intention to use, higher than perceived usefulness. Instead of broadening the quantitative study to a wider group of users we investigate deeper with qualitative interviews based on diffusion of innovation and different adoption models. Firstly three hypotheses are formulated on basis of the survey. Secondly our qualitative results give a richer explanation and show our group of respondents value the quality of the music recommendation mechanism over extra other functionalities like social networking, blogging and scrobbling. The latter result is important for music service suppliers in their highly competitive market.
A hierarchical neural network approach to the development of library of neural models for microwave design

Neural networks recently gained attention as a fast and flexible vehicle to microwave modeling simulation and optimization. This paper addresses a new challenge in this area, i.e., development of libraries of microwave neutral models. A hierarchical neural network framework is presented utilizing the knowledge of basic relationships common to all library components. The proposed method improves the reliability of neural models, while significantly reducing the cost of library development through reduced need for data collection and shortened time of training.
Retinoid signaling and activator protein-1 expression in ferrets given beta-carotene supplements and exposed to tobacco smoke.

BACKGROUND Epidemiologic studies have demonstrated that individuals who eat more fruits and vegetables and/or have high levels of serum beta-carotene have a lower risk of cancer, especially lung cancer. However, recent human intervention studies using beta-carotene supplements have shown an increase in the risk of lung cancer among smokers and asbestos workers. In this study, we used an animal model system to evaluate the hazard associated with a combination of high-dose beta-carotene supplementation and tobacco smoking. METHODS Ferrets were given a beta-carotene supplement, exposed to cigarette smoke, or both for 6 months. Cell proliferation and squamous metaplasia in lung tissue were assessed by examination of proliferating-cell nuclear antigen expression and histopathologic examination, respectively. beta-Carotene and retinoid concentrations in lung tissue and plasma samples were analyzed by high-performance liquid chromatography. Expression of genes for retinoic acid receptors (RARs) and activator protein-1 (encoded by the c-Jun and c-Fos genes) in lung tissue specimens was examined by western blotting. RESULTS A strong proliferative response in lung tissue and squamous metaplasia was observed in all beta-carotene-supplemented animals, and this response was enhanced by exposure to tobacco smoke. When compared with control groups, all three treatment groups had statistically significantly lower concentrations of retinoic acid in lung tissue, and they exhibited 18%-73% reductions in RARbeta gene expression; however, RARalpha and RARgamma gene expression was not reduced. Ferrets given a beta-carotene supplement and exposed to tobacco smoke had threefold to fourfold elevated expression of the c-Jun and c-Fos genes. CONCLUSIONS Diminished retinoid signaling, resulting from the suppression of RARbeta gene expression and overexpression of activator protein-1, could be a mechanism to enhance lung tumorigenesis after high-dose beta-carotene supplementation and exposure to tobacco smoke.
Combined use of free light chain and heavy/light chain ratios allow diagnosis and monitoring of patients with monoclonal gammopathies: Experience of a single institute, with three exemplar case reports

Monoclonal gammopathies are characterized by serum monoclonal component (MC) plus an intact immunoglobulin and a free light chain (FLC), or a combination of both. The measurement of FLC with Freelite® is the standard practice recommended by International Myeloma Working Group guidelines. Recently, Hevylite® heavy/light chains (HLC) assays were introduced to specifically target junctional epitopes between the heavy and light chains of intact immunoglobulins, allowing the independent quantification of the involved (MC) and uninvolved (polyclonal immunoglobulin background) HLC isotype. Between January 2012 and March 2014, 90 patients were examined: 49 multiple myeloma (MM), 6 smoldering MM (SMM) and 35 monoclonal gammopathy of undetermined significance (MGUS). Of these 90 patients, 300 samples were collected at different times. The diagnostic and monitoring contribution of Hevylite A and G assays was assessed in all 90 patients examined. Additionally, 3 representative cases were selected. The Hevylite absolute values and ratio demonstrated high sensitivity and specificity with respect to serum protein electrophoresis and serum immunofixation. The combined use of Hevylite A and G with Freelite was particularly useful in dubious cases with more than one MC or with co-migrating components, as well as in the course of monitoring to assess the independent change of FLC and HLC, possibly reflecting the presence of clonal heterogeneity in the cohort. From this study, it can be concluded that FLC and HLC are independent, useful markers to monitor the MC and to assess with greater specificity and sensitivity the effect of therapy, thereby providing clinical support. Further studies are required to assess the prognostic potential of Hevylite in MGUS and SMM.
Global finite amplitude perturbations in medium aspect ratio pipe flow

Results of a numerical study on the finite amplitude global perturbations inducing transition to turbulence in pipe flow are reported. The aim of this analysis is to characterise the basin of attraction of the basic Hagen-Poiseuille flow (which is believed to be lineary stable for all Reynolds numbers Re) by means of the minimal amplitude of an initial global perturbation triggering transition. Subcritical transition in pipe flow is extremely sensitive to the shape of the initial perturbation. The analysis is focused on the streak breakdown transition scenario, by which the basic flow, perturbed with streamwise-independent disturbances of azimuthal wave number n = 1, develops transient streaks that are susceptible of being destabilised by much smaller streamwise-dependent perturbations. The numerical simulations cover a wide range of Reynolds numbers Re ∊ [2500, 104] and the transition dynamics are spectrally resolved by the numerical method. The threshold amplitude of perturbations seems to decrease with Re−3/2 within the studied range.
A Visual System for Mining Crime Mining across College Campuses

The safety of college campuses is neither an unexpected nor new phenomenon. High school students and their parents consider a variety of factors, like academic quality, cost of attendance, campus appearance, and campus safety, before making the final decision of their choice of college [2]. “Campus safety” has been the factor with the steadiest increase across generations. In a 1997 conducted poll by the Art & Science Group [1], 64% of parents and 57% of students rated having a safe campus as “very important” in their choice of college. This rating paralleled the rating for academic reputation and prestige. The study was repeated over the years, and in 2016, 72% of students indicated that campus safety was very important to them in college consideration and choice, and 86% of them reported that it was very important to their parents [2]. In this project, we have two main goals: (1) collect data in real-time from the web sites of these institutions and (2) create a visual and intuitive tool that projects crimes within and around a college campus area. Campus crime data is publicly available at most U.S. postsecondary institutions. While there are such tools available, they present static pictures or graphs. Our goal is to give animated temporalspatial heat maps that show animations of the evolution of crime density in and around a college campus. Figure 1 illustrates one of the heat maps produced with our tool. Such a tool can: • help students and parents make informed decisions (often, decisions are made based on word-of-mouth or“onceupon-a-time”stories instead of up-to-date factual data), • help various university and city departments coordinate and devise common safety programs, • protect students, faculty, and administration by pinpointing areas and times to exercise caution.
Technical innovation success in China: The use of innovation mechanisms in Chinese SOEs

Climate for technical innovation has been improving in the past few years in China. This Paper describes a case research related to technical innovation in three Chinese state-owned enterprises (SOEs) in the manufacturing industry, by applying a Western technical audit tool. The data and findings reveal that the investigated Chinese SOEs have already some mechanisms for innovation in place but there is room for improvement and enhancement with respect to the effect on innovation success. It is also concluded that benchmarking (through the application of the audit tool) may not guarantee improved innovation performance, but it does guide management toward deciding which innovation mechanisms to adopt so as to provide the basics for innovation success. Last but not least we draw the interesting conclusion that in the economy in transition in China, companies with less openness to the market (i.e. with high government involvement), there was a more widespread use of innovation mechanisms. This finding seems to contradict the positive relationship between market focus and innovativeness as suggested in ‘Western’ innovation management theories, and it enriches to a certain extent the theory of transition.
Magnetic Field during Wireless Charging in an Electric Vehicle According to Standard SAE J2954

The Society of Automotive Engineers (SAE) Recommended Practice (RP) J2954 (November 2017) was recently published to standardize the wireless power transfer (WPT) technology to recharge the battery of an electric vehicle (EV). The SAE J2954 RP establishes criteria for interoperability, electromagnetic compatibility (EMC), electromagnetic field (EMF) safety, etc. The aim of this study was to predict the magnetic field behavior inside and outside an EV during wireless charging using the design criteria of SAE RP J2954. Analyzing the worst case configurations of WPT coils and EV bodyshell by a sophisticated software tool based on the finite element method (FEM) that takes into account the field reflection and refraction of the metal EV bodyshell, it is possible to numerically assess the magnetic field levels in the environment. The investigation was performed considering the worst case configuration—a small city car with a Class 2 WPT system of 7.7 kVA with WPT coils with maximum admissible ground clearance and offset. The results showed that the reference level (RL) of the International Commission on Non-Ionizing Radiation Protection (ICNIRP) guidelines in terms of magnetic flux density was exceeded under and beside the EV. To mitigate the magnetic field, the currents flowing through the WPT coils were varied using the inductor-capacitor-capacitor (LCC) compensation instead of the traditional series-series (SS) compensation. The corresponding calculated field was compliant with the 2010 ICNIRP RL and presented a limited exceedance of the 1998 ICNIRP RL. Finally, the influence of the body width on the magnetic field behavior adopting maximum offset was investigated, demonstrating that the magnetic field emission in the environment increased as the ground clearance increased and as the body width decreased.
RN Workgroup Job Satisfaction and Patient Falls in Acute Care Hospital Units

OBJECTIVE: The aim of this study was to examine the relationship between registered nurse (RN) workgroup job satisfaction and patient falls on 4 types of acute care hospital units. BACKGROUND: Although a link has been found between nurse job satisfaction and quality of patient care, little research has been conducted to examine the effect of RN job satisfaction on patient clinical outcomes in acute care hospitals. METHODS: Random-intercept negative binomial regression analyses were performed using 2009 unit-level data from 2,763 units in 576 National Database of Nursing Quality Indicators hospitals. RESULTS: Controlling for unit (nurse staffing, RN education, and RN unit tenure) and hospital (Magnet® status, hospital size, and teaching status) characteristics, RN workgroup job satisfaction was inversely associated with patient falls (incident rate ratio, 0.941, 95% confidence interval, 0.911-0.972). CONCLUSIONS: Higher RN workgroup job satisfaction is significantly related to fewer patient falls on acute care hospital units.