Miracle-dz/UniFAR-FTUs huggingface dataset:
Voltage-mode universal filters employing single modified current feedback operational amplifier (MCFOA)

This paper deals with the modified current-feedback operational amplifier (MCFOA) that is used in two voltage-mode (VM) frequency filters. Both structures presented employ single active and five passive elements. Circuits enable realizing a low- (LP), band- (BP), and high-pass (HP) filter responses without changing the circuit topology. There is no requirement for additional component or rotation of component to realize band-stop (BS) and all-pass (AP) filter function. Moreover, the independent adjustment of the quality factor Q by varying the value of single passive element without affecting of the natural frequency ¿0 is allowed. All the passive and active sensitivities are low. In the PSPICE simulations the BJT simulation model of the MCFOA and its possible realization using the UCC-N1B 0520 integrated circuit are used to confirm the workability of the proposed circuits.
The Reproductive Tissue Specific Cystatin Subgroup of Genes: Expression during Gonadal Development in Wildtype and Testatin Knockout Animals

Testatin has been implicated in fetal testis development due to its restricted expression in pre-Sertoli cells immediately after the onset of Sry gene expression. However, testatin knockout mice showed normal testis development and fertility. We investigated the spatial and temporal expression pattern of the Cres/testatin subgroup of genes, including the novel gene Cstl1/Cres4, in fetal mouse gonads and in adult testis, epididymis and ovary. The genes are related to the family 2 cystatins of protease inhibitors. Using real-time PCR and in situ hybridization we could show that 4 subgroup genes, testatin, CstSC, CstTE-1/Cres3 and Cres are expressed in fetal testis. We also confirmed the expression of testatin, CstE2, CstSC, CstTE-1/Cres3, Cres, CstT and Cstl1/Cres4 in adult testis and CstE2, CstTE-1/Cres3, Cres and CstE1/Cres2 in adult epididymis. In testatin knockout animals, the expression of CstE2 was heavily downregulated in adult testis, but not in adult epididymis, compared to wildtype controls. In conclusion, an explanation for the lack of phenotype in testatin knockout mice could be functional redundancy with another member of the Cres/testatin subgroup. The most likely candidate/s would be CstSC, CstTE-1/Cres3 or Cres as they are expressed in the fetal testicular tubules in early testis differentiation together with testatin.
Synthesis, Docking Study & Anticancer Evaluation of Novel 3-Phenyl- 2-(3-aryl-1-phenyl-1H-pyrazol-4-yl)thiazolidin-4-ones

On account of the reported anticancer activity of pyrazoles and thiazolidin-4-ones, we have designed and synthesized a series of novel 3-phenyl-2-(3-aryl-1-phenyl-1H-pyrazol-4-yl)thiazolidin-4-ones and investigated their COX-1 and COX-2 inhibition potential and also their in vitro cytotoxic activity by MTT assay. Amongst the tested compounds, the compound 3e was found to be most potent COX-2 inhibitor with IC50 value of 4.4 μM and showed promising anticancer potential with IC50 values of 14.78 μg/ml and 12.45 μg/ml against HT-29 and COLO-205 cancer cells, respectively, compared to 5-FU as a standard drug. The newly synthesized compounds were characterized by melting point, IR, 1H NMR, and MS analysis. Docking studies were performed on the active site of COX-1 and COX-2 enzymes.
Experimental psychology and the courtroom

Experimental social and cognitive psychology cover a range of topics such as attitudes, attribution, decision making, perception, memory, comprehension, and reasoning. The relevance of these topics to the law is apparent in such domains as jury selection, jury behavior, plea bargaining, eyewitness testimony, sentencing, and police investigation strategies. Despite early attempts to apply experimental psychology to law (circa 1900–1920), it was not until the mid 1970s that a robust law-relevant literature in experimental psychology began to unfold. The experimental psychology/law interface continues to experience some problems in (1) generalizing from specific research experiments to real-world conditions, and (2) identifying solutions rather than just problems.
Space vs. Networks in the Geography of Innovation: A European Analysis

In the last fifteen years, income differences among European Member States have been strongly narrowing while the process has been matched with a widening of the inter-regional variance within single countries. Traditionally, regional economic disparities in Europe have been ascribed to peripherality and/or to a high level of dependence on declining sectors. Nowadays regional disparities can be no longer defined only in terms of statistical differences in the values of standard macroeconomic indicators, but also according to innovative capacities and knowledge endowment. This paper provides an original framework for the interpretation of the existing relationships between innovation process and research activity in Europe and the structural and geographical features shaping the European scientific and technological map. In order to do so, we focus on two knowledge-based relational phenomena: participation in the same research networks (funded by the EU Fifth Framework Programme) and EPO co-patent applications. Using two complementary econometric techniques we try to assess those factors that determine patenting activity, distinguishing structural features, geographical and relational spillovers. Through these variables we measure the intrinsic relational structure of knowledge flows which directly connects people, institutions and, indirectly, regions, across European countries in order to test whether hierarchical relationships based on a-spatial networks between geographically distant excellence centres prevail over diffusive patterns based on spatial contiguity.
Caveolae and sorting in the trans‐Golgi network of epithelial cells.

VIP21 is a 21 kDa membrane protein present in TGN‐derived transport vesicles isolated from the epithelial MDCK cell line. The membrane topology and subcellular localization of VIP21 were studied using antibodies against the N‐ and C‐terminal domains. The protein was found to have a structure with little or no exposure to the exoplasmic side of the membrane. VIP21 was localized to the TGN, consistent with its presence in TGN‐derived transport vesicles. Unexpectedly, it was also very abundant in the non‐clathrin‐coated plasma membrane invaginations called caveolae. We have previously proposed that VIP21 is associated with glycosphingolipid‐enriched membrane domains in the TGN which may be involved in the sorting of proteins into vesicles directed to the apical plasma membrane. Caveolae are specialized lipid structures with similarities to the glycolipid microdomains in the TGN. The presence of VIP21 in both locations suggests that the mechanisms governing inclusion of proteins into caveolar plasma membrane domains are related to the processes of protein and lipid sorting at the TGN. This connection is confirmed by the recent finding that the amino acid sequence of VIP21 is almost identical to that of caveolin, a protein previously localized to caveolae.
Cooperative communication MAC (CMAC) - a new MAC protocol for next generation wireless LANs

Reliability is a big challenge to any wireless transmission as wireless networks tend to drop a large proportion of frames due to channel errors. To improve reliability over the noisy wireless channels, forward error correction (FEC) schemes can be employed for wireless networks. Static and adaptable FEC algorithms can improve or degrade the performance of the wireless networks if their overheads are not matched properly to the underlying channel error, especially when the path loss fluctuates widely. This paper provides a new approach of alleviating the problem from a pure medium access control (MAC) centric perspective. The new MAC protocol, called cooperative MAC (CMAC) enhances the existing IEEE 802.11e wireless local area network (WLAN) MAC protocol by introducing spatial diversity which is provided via user cooperation. We prove that this protocol greatly enhances the robustness of the WLAN operation. Additionally we compare the performance of CMAC protocol with the direct and multi-hop transmissions.
Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome

Maturation of wild‐type CFTR nascent chains at the endoplasmic reticulum (ER) occurs inefficiently; many disease‐associated mutant forms do not mature but instead are eliminated by proteolysis involving the cytosolic proteasome. Although calnexin binds nascent CFTR via its oligosaccharide chains in the ER lumen and Hsp70 binds CFTR cytoplasmic domains, perturbation of these interactions alone is without major influence on maturation or degradation. We show that the ansamysin drugs, geldanamycin and herbimycin A, which inhibit the assembly of some signaling molecules by binding to specific sites on Hsp90 in the cytosol or Grp94 in the ER lumen, block the maturation of nascent CFTR and accelerate its degradation. The immature CFTR molecule was detected in association with Hsp90 but not with Grp94, and geldanamycin prevented the Hsp90 association. The drug‐enhanced degradation was decreased by lactacystin and other proteasome inhibitors. Therefore, consistent with other examples of countervailing effects of Hsp90 and the proteasome, it would seem that this chaperone may normally contribute to CFTR folding and, when this function is interfered with by an ansamycin, there is a further shift to proteolytic degradation. This is the first direct evidence of a role for Hsp90 in the maturation of a newly synthesized integral membrane protein by interaction with its cytoplasmic domains on the ER surface.
Feminist Issues in Qualitative Research With Formerly Homeless Mothers

This article describes the author's attempts to incorporate feminist principles into a qualitative study of the process of successful restabilization among formerly homeless mother-headed families. It discusses methods for dealing with such issues as the research agenda, epistemology, and ethics, so the credibility and agenda of feminist qualitative research is not compromised, and presents case examples from the author's field journals and transcripts of interviews.
Lactate isotopomer analysis by 1H NMR spectroscopy: Consideration of long‐range nuclear spin–spin interactions

Lactate is a key metabolite and its rates of cellular uptake and release, its production rates from glucose and glycogen, and its interconversion rate with pyruvate are important determinants of cellular energy production. If lactate precursors such as pyruvate and glucose are labeled appropriately with 13C, 1H NMR spectroscopy provides a means of quantifying lactate production from each source and allows measurement of all these rates within a single experiment. However, due to the multiplicities of the resonance lines (from nuclear spin–spin couplings) in lactate 13C isotopomers, the 1H NMR spectra were found to be more complex than expected, requiring determination of all spin–spin interactions in this anion. All such values were determined for lactate and its precursor pyruvate. The method was then applied to simultaneously measure the rates of exogenous lactate uptake and rates of release of glucose‐, glycogen‐, and pyruvate‐derived lactate in the isolated perfused rat heart. Magn Reson Med 51:1279–1282, 2004. © 2004 Wiley‐Liss, Inc.
Robust spectral representation using group delay function and stabilized weighted linear prediction for additive noise degradations

In this paper, we propose a robust spectral representation using the group delay (GD) function computed from the stabilized weighted linear prediction (SWLP) coefficients. Temporal weighting of the cost function in linear prediction (LP) analysis with the short-term energy of the speech signal improves the robustness of the resultant spectrum. The additive property of the group delay function provides for better representation of weaker resonances in the spectrum, and thereby improving the robustness of the representation. The SWLP provides robustness in the temporal domain, whereas the GD function provides robustness in the frequency domain. The proposed SWLP-GD representation is shown to be robust against different types of additive noise degradations, compared to the popularly used discrete Fourier transform (DFT) or LP based representations. In a small-scale closed-set speaker recognition experiment, the cepstral features derived from the proposed SWLP-GD spectrum perform better than the traditional mel-cepstral features computed from the discrete Fourier transform (DFT) spectrum under conditions of mismatched degradations.
Paraphrase Identification Using Weighted Dependencies and Word Semantics

In this paper we propose a novel approach to the task of paraphrase identification. The proposed approach quantifies both the similarity and dissimilarity between two sentences. The similarity and dissimilarity is assessed based on lexico-semantic information, i.e., word semantics, and syntactic information in the form of dependencies, which are explicit syntactic relations between words in a sentence. Word semantics requires mapping words onto concepts in a taxonomy and then using word-to-word similarity metrics to compute their semantic relatedness. Dependencies are obtained using state-of-the-art dependency parsers. One important aspect of our approach is the weighting of missing dependencies, i.e., syntactic relations present in one sentence but not the other. We report experimental results on the Microsoft Paraphrase Corpus, a standard data set for evaluating approaches to paraphrase identification. The experiments showed that the proposed approach offers state-of-the-art results. In particular, our approach offers better precision when compared to other state-of-the-art systems.
What Is Research in Mathematics Education, and What Are Its Results?.

scientific research (if not as a scientific discipline), exactly what this research is and what its results are have become less clear. The history of the past three International Congresses on Mathematical Education demonstrates the need for greater clarity. At the Budapest congress in 1988, in particular, there was a general feeling that mathematics educators from different parts of the world, countries, or even areas of the same country often talk past one another. There seems to be a lack of consensus on what it means to be a mathematics educator. Standards of scientific quality and the criteria for accepting a paper vary considerably among the more than 250 journals on mathematics education published throughout the world. The community of people concerned with research in mathematics education is increasingly divided into specialized groups and cliques that are not always tolerant of each other. Besides mutual understanding within the community, however, there is also a need to explain the domain to representatives of other scientific communities, among which the community of mathematicians seems to be the most important. Many people want to develop research in mathematics education within the academic community of mathematicians. This implies both the explanation of the research's purpose on a social ground (Is there any need to develop such research? ) and its relevance within the narrow academic world. Questions arise as to scientific standards, dissertations, publications, congresses, the employment of young academics in the field, and the connection between this research and the research done in other fields. Thus we
Basic Physical Capability Scale

The purpose of this study was to evaluate the reliability and validity of the Basic Physical Capability Scale when used with older adults having moderate to severe cognitive impairment and consider the utility of the measure in establishing function-focused care (FFC) goals for these individuals. The study was a secondary data analysis using data from 2 intervention studies testing FFC interventions in older adults with moderate to severe cognitive impairment in nursing homes and assisted living settings. Participants included 96 recruited from 4 assisted living facilities and 103 older adults from 4 nursing homes. There was support for validity of the measure based on construct validity and hypothesis testing, internal consistency (Cronbach's α of .79), and utility of the measure. Recommendations are provided for additional items that might help better differentiate individuals with moderate to severe cognitive impairment who are particularly high or low in basic physical capability.
Exploring the Psychological Rewards of a Familiar Semirural Landscape: Connecting to Local Nature through a Mindful Approach

This study analyses a 53,000-word diary of a year engaging with nature through over 200 trips to a semirural landscape. Thematic analysis revealed two themes: the transition from observer to nature connectedness and the ways in which the natural environment was experienced once a connection was made. These themes are discussed in relation to theories that seek to explain the positive effect of nature and nature connectedness. The findings are important as they suggest that repeated engagement with local semirural countryside can lead to a mindful approach and psychological rewards that do not require travel into the wilderness. The work informs further research into outcomes and processes of nature-based interventions, such as trip frequency, duration, and diary keeping.
Face Recognition using 2.5D Shape Information

In this paper we investigate whether the 2.5D shape information delivered by a novel shape-from-shading algorithm can be used for illumination insensitive face recognition. We present a robust and efficient facial shape-fromshading algorithm which uses principal geodesic analysis to model the variation in surface orientation across a face. We show how this algorithm can be used to recover accurate facial shape and albedo from real world images. Our second contribution is to use the recovered 2.5D shape information in a variety of recognition methods. We present a novel recognition strategy in which similarity is measured in the space of the principal geodesic parameters. We also use the recovered shape information to generate illumination normalised prototype images on which recognition can be performed. Finally we show that, from a single input image, we are able to generate the basis images employed by a number of well known illumination-insensitive recognition algorithms. We also demonstrate that the principal geodesics provide an efficient parameterisation of the space of harmonic basis images.
Optimal Translation Boundaries for BTG-Based Decoding

This paper proposes a method for inducing translation boundaries as soft constraints for Bracketing Transduction Grammar based (BTG-based) decoding. Translation boundaries used in previous research are extracted from left-most synchronous trees generated by a deterministic algorithm. Translation boundaries in this research are extracted from induced synchronous trees, which are statistically optimal and more balanced than the left-most synchronous trees. Experiments show that induced translation boundaries are more consistent than those extracted from left-most synchronous trees, resulting in significantly better performances over the strong baseline.
Coding the Environment in Tactile Maps for Real-Time Guidance of the Visually Impaired

This paper explores an application of computer vision and touch stimulating interfaces for developing a novel electronic travel aid (ETA): the Intelligent Glasses (IG). The IG is a new sensory substitution/supplementation supportive system that provides tactile maps of visual spaces and possible paths for navigating these spaces so that the visually impaired can easily perform independent, safe and efficient mobility tasks. A technical overview of the system is presented as well as preliminary results that strongly suggest that environmental information presented to the sense of touch is feasible for realtime guidance of the visually impaired
Aschoff Bodies in Operatively Excised Atrial Appendages and in Papillary Muscles: Frequency and Clinical Significance

Among 481 patients undergoing various mitral valve operations, Aschoff bodies were found in 40 (21%) of 191 operatively excised left atrial appendages, in four (2%) of 273 operatively excised left ventricular papillary muscles (1 per patient), and in one (6%) of 17 patients with both left atrial appendage and papillary muscle operatively excised. Of the total of 45 patients with Aschoff bodies, 44 preoperatively had mitral stenosis, and only one, a 10-year-old boy, had pure mitral regurgitation. Sinus rhythm was present in 38 (84%), and atrial fibrillation in seven (16%). Perioperatively, only one of the 45 patients with Aschoff bodies had clinical or laboratory stigmata compatible with acute rheumatic fever, and 58% had an illness compatible with acute rheumatic fever at any time.
Sexuality and the Suburban Dream

It is now generally accepted that Australian society is neither classless nor egalitarian. But, while the ’embourgeoisment’ hypothesis has been firmly rejected (Connell, 1977; Wild, 1978), we need to examine the ways in which the ideology of embourgeoisment is generated and lived. This paper concentrates on the development of new consumption patterns, the increasing uniformity of family form and the extension of the suburban dream, in relation to a continuing reorganisation of the dominant structure of sexuality. In particular we argue that some men were able to experience a measure of equality, but only through the labour of women as full time housewives and low paid super-exploited workers in factories, shops and offices. The boom conditions following World War Two enabled a sizeable proportion of the working class to achieve the ideal of homeownership and a privatised family life in the suburbs. The suburban dream centred on women’s role in the home as full-time wives and mothers; but its achievement depended on their contribution as domestic and wage labourers. It was based on a clearcut gender division and unequal power relations between men and women. Along with the sexual division of labour went a construction of sexuality which emphasised the polarity between male and female. Being appropriately ’masculine’ or ’feminine’ became the key to personal fulfilment. There was a ’sexualisation’ of everyday life through the invocation of sexual desire that could not be fulfilled. This explains how at the personal level people found consumerism so attractive and meaningful. Commodities themselves took on an erotic significance, since they offered to fulfil the ideals of masculinity and femininity. This new pattern of consumption was a central part of the suburban dream.
Principals' Knowledge of Fundamental and Current Issues in Special Education

The purpose of the study is to determine the comprehensive knowledge base of national secondary principals related to special education issues. Using a survey developed from the empirical and conceptual literature for assessing fundamental and current issues in special education, data were collected from a national sample of secondary school principals. Overall, principals report being well informed in fundamental issues. Although the relationship between demographics and knowledge produced mixed results, principal practices have a positive relationship with knowledge of special education issues.